Guide to the Human Genome
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Search of human proteins with 113421234

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|113421234 PREDICTED: similar to NG5 protein [Homo sapiens]
         (288 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|113421234 PREDICTED: similar to NG5 protein [Homo sapiens]         599   e-172
gi|113420954 PREDICTED: similar to NG5 protein [Homo sapiens]         599   e-172
gi|169178462 PREDICTED: similar to NG5 protein [Homo sapiens]         184   6e-47
gi|77681565 NG5 protein [Homo sapiens]                                 89   4e-18
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    76   4e-14
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    74   1e-13
gi|163965366 nascent polypeptide-associated complex alpha subuni...    73   3e-13
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    71   1e-12
gi|21389357 MAPK-interacting and spindle-stabilizing protein [Ho...    70   3e-12
gi|210032580 SET domain containing 1B [Homo sapiens]                   67   2e-11
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...    65   7e-11
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...    65   7e-11
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...    65   7e-11
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]               64   1e-10
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    64   2e-10
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    64   2e-10
gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho...    62   8e-10
gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Ho...    62   8e-10
gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Ho...    62   8e-10
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       61   1e-09
gi|47132519 Ras association and pleckstrin homology domains 1 is...    61   1e-09
gi|165905613 ring finger and KH domain containing 1 [Homo sapiens]     60   2e-09
gi|119508426 alpha 3 type IX collagen [Homo sapiens]                   60   2e-09
gi|57863314 vacuolar protein sorting 37C [Homo sapiens]                60   2e-09
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  59   6e-09
gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo s...    58   8e-09
gi|18959210 WIRE protein [Homo sapiens]                                58   8e-09
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    58   1e-08
gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]        57   2e-08
gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]        57   2e-08

>gi|113421234 PREDICTED: similar to NG5 protein [Homo sapiens]
          Length = 288

 Score =  599 bits (1545), Expect = e-172
 Identities = 288/288 (100%), Positives = 288/288 (100%)

Query: 1   MGRTSPICKQLREMLERWPLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKG 60
           MGRTSPICKQLREMLERWPLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKG
Sbjct: 1   MGRTSPICKQLREMLERWPLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKG 60

Query: 61  GGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGA 120
           GGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGA
Sbjct: 61  GGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGA 120

Query: 121 PHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFS 180
           PHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFS
Sbjct: 121 PHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFS 180

Query: 181 PPAGAAFPFPVYNGPMAGVPGPATVEHRPLPKDYMMESVLVTLFCCLLTGLIAIVYSHEA 240
           PPAGAAFPFPVYNGPMAGVPGPATVEHRPLPKDYMMESVLVTLFCCLLTGLIAIVYSHEA
Sbjct: 181 PPAGAAFPFPVYNGPMAGVPGPATVEHRPLPKDYMMESVLVTLFCCLLTGLIAIVYSHEA 240

Query: 241 RAALGRGDLAQAEEASRKARSLVLFSLLFGVFVSTSWVIYVVVALYLP 288
           RAALGRGDLAQAEEASRKARSLVLFSLLFGVFVSTSWVIYVVVALYLP
Sbjct: 241 RAALGRGDLAQAEEASRKARSLVLFSLLFGVFVSTSWVIYVVVALYLP 288


>gi|113420954 PREDICTED: similar to NG5 protein [Homo sapiens]
          Length = 288

 Score =  599 bits (1545), Expect = e-172
 Identities = 288/288 (100%), Positives = 288/288 (100%)

Query: 1   MGRTSPICKQLREMLERWPLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKG 60
           MGRTSPICKQLREMLERWPLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKG
Sbjct: 1   MGRTSPICKQLREMLERWPLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKG 60

Query: 61  GGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGA 120
           GGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGA
Sbjct: 61  GGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGA 120

Query: 121 PHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFS 180
           PHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFS
Sbjct: 121 PHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFS 180

Query: 181 PPAGAAFPFPVYNGPMAGVPGPATVEHRPLPKDYMMESVLVTLFCCLLTGLIAIVYSHEA 240
           PPAGAAFPFPVYNGPMAGVPGPATVEHRPLPKDYMMESVLVTLFCCLLTGLIAIVYSHEA
Sbjct: 181 PPAGAAFPFPVYNGPMAGVPGPATVEHRPLPKDYMMESVLVTLFCCLLTGLIAIVYSHEA 240

Query: 241 RAALGRGDLAQAEEASRKARSLVLFSLLFGVFVSTSWVIYVVVALYLP 288
           RAALGRGDLAQAEEASRKARSLVLFSLLFGVFVSTSWVIYVVVALYLP
Sbjct: 241 RAALGRGDLAQAEEASRKARSLVLFSLLFGVFVSTSWVIYVVVALYLP 288


>gi|169178462 PREDICTED: similar to NG5 protein [Homo sapiens]
          Length = 93

 Score =  184 bits (468), Expect = 6e-47
 Identities = 93/93 (100%), Positives = 93/93 (100%)

Query: 196 MAGVPGPATVEHRPLPKDYMMESVLVTLFCCLLTGLIAIVYSHEARAALGRGDLAQAEEA 255
           MAGVPGPATVEHRPLPKDYMMESVLVTLFCCLLTGLIAIVYSHEARAALGRGDLAQAEEA
Sbjct: 1   MAGVPGPATVEHRPLPKDYMMESVLVTLFCCLLTGLIAIVYSHEARAALGRGDLAQAEEA 60

Query: 256 SRKARSLVLFSLLFGVFVSTSWVIYVVVALYLP 288
           SRKARSLVLFSLLFGVFVSTSWVIYVVVALYLP
Sbjct: 61  SRKARSLVLFSLLFGVFVSTSWVIYVVVALYLP 93


>gi|77681565 NG5 protein [Homo sapiens]
          Length = 306

 Score = 89.0 bits (219), Expect = 4e-18
 Identities = 91/288 (31%), Positives = 110/288 (38%), Gaps = 37/288 (12%)

Query: 19  PLPAAPPSRTPPQTLK----------HLPSGEPGPPFPAGMPGGGSGSDTKGGGSPAT-P 67
           P P A P   PPQ             H       P   AG     + +  +G  S AT P
Sbjct: 23  PQPPAEPPAPPPQAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSAATAQRGPSSSATLP 82

Query: 68  EDPR-SPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFV 126
             P  +P  PAA   P  P    LP++P  P  L E    G   P   AAA         
Sbjct: 83  RPPHHAPPGPAAGAPP--PGCATLPRMPPDPY-LQETRFEGPLPPPPPAAAA-------- 131

Query: 127 GEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPP-PAQLYPAAPTPPALFSPPAGA 185
             PPP AP     AP    P     V   P    + P  P QL P     P     P G 
Sbjct: 132 --PPPPAPAQTAQAPGFVVPTHAGTVGTLPLGGYVAPGYPLQLQPCTAYVPVY---PVGT 186

Query: 186 AFPFPVYNG--------PMAGVPGPATVEHRPLPKDYMMESVLVTLFCCLLTGLIAIVYS 237
            +      G        P    PG A +E R  P DYM  +VL T+ C   TG+IAI  +
Sbjct: 187 PYAGGTPGGTGVTSTLPPPPQGPGLALLEPRRPPHDYMPIAVLTTICCFWPTGIIAIFKA 246

Query: 238 HEARAALGRGDLAQAEEASRKARSLVLFSLLFGVFVSTSWVIYVVVAL 285
            + R AL RGD+  AE ASR+AR+    SL  G+       I  VV +
Sbjct: 247 VQVRTALARGDMVSAEIASREARNFSFISLAVGIAAMVLCTILTVVII 294



 Score = 34.7 bits (78), Expect = 0.100
 Identities = 34/109 (31%), Positives = 41/109 (37%), Gaps = 28/109 (25%)

Query: 129 PPPYAPPDPKAAPLLYPPFPQVPVVLQPAPS--------------ALFPPPAQLYPAAPT 174
           PPPY  P P A P   PP        Q APS              A  P       A+  
Sbjct: 17  PPPYNAPQPPAEPPAPPP--------QAAPSSHHHHHHHYHQSGTATLPRLGAGGLASSA 68

Query: 175 PPALFSPPAGAAFPFPVYN---GPMAGVPGP--ATVEHRPLPKDYMMES 218
             A   P + A  P P ++   GP AG P P  AT+   P P  Y+ E+
Sbjct: 69  ATAQRGPSSSATLPRPPHHAPPGPAAGAPPPGCATLPRMP-PDPYLQET 116


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 65/215 (30%), Positives = 80/215 (37%), Gaps = 33/215 (15%)

Query: 19  PLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAA 78
           PLP APPS + P +L+ LPS    PP  A    G           P+ P  P +   P A
Sbjct: 337 PLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 396

Query: 79  P---------EDPQMPAQPALPQL----PRRPRTL-----------------DEDGAAGE 108
           P           P  PA P L  L    P+ P  L                     +   
Sbjct: 397 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 456

Query: 109 AGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYP---PFPQVPVVLQPAPSALFPPP 165
           + PVS +A   +     +  PP   PP P A+P + P   P PQ P  L   P  L  PP
Sbjct: 457 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 516

Query: 166 AQLYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVP 200
            Q  PA  TPP    P   A+FP      P A +P
Sbjct: 517 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 551



 Score = 58.5 bits (140), Expect = 6e-09
 Identities = 69/230 (30%), Positives = 86/230 (37%), Gaps = 53/230 (23%)

Query: 19  PLPAAPPS-RTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPA 77
           P P APP+  TPP  L+ LPS  P   FP   P   S S      +   P+ P   A P 
Sbjct: 515 PPPQAPPALATPP--LQALPS--PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 570

Query: 78  APEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGP-VSKAAAGGAPHIGFVGEPPPYAPPD 136
               P  PA P L Q PRRP T   D +   +GP ++ A A G P       PP  +P  
Sbjct: 571 LQVPPSPPASPTL-QAPRRPPTPGPDTSV--SGPRLTLALAPGPP------PPPSRSPSS 621

Query: 137 PKAAPLL----------------YPPFPQVPVVLQPAPSALFPPPAQLYPAA----PTPP 176
             + P L                Y   P+      P P A     A  +PAA    P PP
Sbjct: 622 TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL---AACHPAAWSRGPAPP 678

Query: 177 ALFSPPAGAAFPFP-------------VY--NGPMAGVPGPATVEHRPLP 211
             F    GA  P+P             +Y   GP +  P P  ++  P P
Sbjct: 679 LAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 728



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 64/227 (28%), Positives = 85/227 (37%), Gaps = 47/227 (20%)

Query: 19  PLPAA---PPSRTPPQTLKHLPSGEPGPPFPAGM--PGGGSGSD---TKGGGSPATPEDP 70
           P P+A   PP+  P +++          P PA    P  G G     ++   S ATP   
Sbjct: 192 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 251

Query: 71  RSPAKPAAPEDPQMPAQPALP-----QLPRRPR-TLDEDGAAGEAGPVSKA-AAGGAPHI 123
            + + P+A   P+ PA P+ P     Q  R P+ T     AA   GP+S +  A  +P  
Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA 311

Query: 124 GFVGEPPPYAPPDPKAAPL---------LYPPFPQVPVVLQPAPSALFPPPAQ------- 167
               + PP  P  P ++ L         L PP P  P  LQ  PS    PP+Q       
Sbjct: 312 ALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGS 371

Query: 168 --------------LYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVP 200
                         L P A  PP   +PPA A  P      P A  P
Sbjct: 372 PTLQATHSFLPSPPLSPLATPPPQ--APPALALPPLQAPPSPPASPP 416



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 58/209 (27%), Positives = 72/209 (34%), Gaps = 38/209 (18%)

Query: 21  PAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPA-KPAAP 79
           P +PP  +PP      P   P P  P+  P   +            P  P SP   P+A 
Sbjct: 439 PFSPPP-SPPVQAPFSPPASP-PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 496

Query: 80  EDPQMPAQPALPQL------PRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPP--- 130
             PQ P   A P L      P+ P  L        A P  +A    +P   F G+ P   
Sbjct: 497 PPPQAPPPLAAPPLQLAKPPPQAPPAL--------ATPPLQALP--SPPASFPGQAPFSP 546

Query: 131 -------PYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPP- 182
                  P A P P+A P+L  P  QVP    P+P A     A   P  P P    S P 
Sbjct: 547 SASLPMSPLATPPPQAPPVLAAPLLQVP----PSPPASPTLQAPRRPPTPGPDTSVSGPR 602

Query: 183 ----AGAAFPFPVYNGPMAGVPGPATVEH 207
                    P P    P + + GP    H
Sbjct: 603 LTLALAPGPPPPPSRSPSSTLSGPDLAGH 631



 Score = 36.2 bits (82), Expect = 0.034
 Identities = 53/189 (28%), Positives = 66/189 (34%), Gaps = 19/189 (10%)

Query: 5   SPICKQLREMLERWPLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGG-SGSDTKGGGS 63
           SP      +   R P P    S + P+    L  G P P  P+  P    SG D  G  S
Sbjct: 576 SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP--PSRSPSSTLSGPDLAGHSS 633

Query: 64  PATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHI 123
            AT          + PE     + P   +L           AA   GP    A  GAP  
Sbjct: 634 SATSTPEELRGYDSGPEGGAAASPPPDAELAAC------HPAAWSRGPAPPLAFRGAP-- 685

Query: 124 GFVGEPPPYAP-PDPKAAPLLYPPF-PQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSP 181
              G P P+ P   P +A  L   +  + P    PAP AL P P+   P      A    
Sbjct: 686 ---GAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPS---PGTSGGKAAAGA 739

Query: 182 PAGAAFPFP 190
            AGA+   P
Sbjct: 740 GAGASSRSP 748



 Score = 30.4 bits (67), Expect = 1.9
 Identities = 32/109 (29%), Positives = 40/109 (36%), Gaps = 10/109 (9%)

Query: 18  WPLPAAPPSRTPPQTLKHLPSGE-----PGPPFPAGMPGGGSGSDTKGGGSPATPEDPRS 72
           WP    P S     T+      E     PG   P   PG   G    G G+ A+    RS
Sbjct: 691 WPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGAS---SRS 747

Query: 73  PAKPAAPEDPQMPAQPALPQ--LPRRPRTLDEDGAAGEAGPVSKAAAGG 119
           P +    E P    Q ++ Q  L R       +GAAG +G     A GG
Sbjct: 748 PKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGG 796


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 74.3 bits (181), Expect = 1e-13
 Identities = 64/215 (29%), Positives = 80/215 (37%), Gaps = 33/215 (15%)

Query: 19  PLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAA 78
           P P+APPS + P +L+ LPS    PP  A    G           P+ P  P +   P A
Sbjct: 298 PSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 357

Query: 79  P---------EDPQMPAQPALPQL----PRRPRTL-----------------DEDGAAGE 108
           P           P  PA P L  L    P+ P  L                     +   
Sbjct: 358 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 417

Query: 109 AGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYP---PFPQVPVVLQPAPSALFPPP 165
           + PVS +A   +     +  PP   PP P A+P + P   P PQ P  L   P  L  PP
Sbjct: 418 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 477

Query: 166 AQLYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVP 200
            Q  PA  TPP    P   A+FP      P A +P
Sbjct: 478 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 512



 Score = 58.5 bits (140), Expect = 6e-09
 Identities = 69/230 (30%), Positives = 86/230 (37%), Gaps = 53/230 (23%)

Query: 19  PLPAAPPS-RTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPA 77
           P P APP+  TPP  L+ LPS  P   FP   P   S S      +   P+ P   A P 
Sbjct: 476 PPPQAPPALATPP--LQALPS--PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 531

Query: 78  APEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGP-VSKAAAGGAPHIGFVGEPPPYAPPD 136
               P  PA P L Q PRRP T   D +   +GP ++ A A G P       PP  +P  
Sbjct: 532 LQVPPSPPASPTL-QAPRRPPTPGPDTSV--SGPRLTLALAPGPP------PPPSRSPSS 582

Query: 137 PKAAPLL----------------YPPFPQVPVVLQPAPSALFPPPAQLYPAA----PTPP 176
             + P L                Y   P+      P P A     A  +PAA    P PP
Sbjct: 583 TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL---AACHPAAWSRGPAPP 639

Query: 177 ALFSPPAGAAFPFP-------------VY--NGPMAGVPGPATVEHRPLP 211
             F    GA  P+P             +Y   GP +  P P  ++  P P
Sbjct: 640 LAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 689



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 62/213 (29%), Positives = 83/213 (38%), Gaps = 38/213 (17%)

Query: 19  PLPAA---PPSRTPPQTLKHLPSGEPGPPFPAGM--PGGGSGSD---TKGGGSPATPEDP 70
           P P+A   PP+  P +++          P PA    P  G G     ++   S ATP   
Sbjct: 183 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 242

Query: 71  RSPAKPAAPEDPQMPAQPALP-----QLPRRPR-TLDEDGAAGEAGPVSKAAAGGAPHIG 124
            + + P+A   P+ PA P+ P     Q  R P+ T     AA   GP+S +         
Sbjct: 243 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP-------- 294

Query: 125 FVGEPPPYAPPDPKAAPLL--YPPFPQVP----------VVLQPAPSALFPPPAQ--LYP 170
            +  P P APP P A P L   P  P  P            LQ   S L  PP      P
Sbjct: 295 -LATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP 353

Query: 171 AAPTPPALFSPPAGAAFPFPVYNGPMAGVPGPA 203
               PPAL  PP  A  P P  + P++ +  P+
Sbjct: 354 PPQAPPALALPPLQAP-PSPPASPPLSPLATPS 385



 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 55/190 (28%), Positives = 68/190 (35%), Gaps = 42/190 (22%)

Query: 19  PLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAA 78
           P   A PS+  P+ L+ L   +  PP     P  G  S      SP     P +P  P+A
Sbjct: 254 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS-----SPLATPSPSAPPSPSA 308

Query: 79  PEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAG-GAPHIGFVGEPPPYAPPDP 137
           P        P+L  LP  P T           P S+A    G+P +       P  P  P
Sbjct: 309 P--------PSLQTLPSPPAT-----------PPSQATTSLGSPTLQATHSFLPSPPLSP 349

Query: 138 KAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALF-----SPPAGAAFPFPVY 192
            A P   PP          AP AL  PP Q  P+ P  P L      SP A  A    + 
Sbjct: 350 LATP---PP---------QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL 397

Query: 193 NGPMAGVPGP 202
             P +  P P
Sbjct: 398 QAPFSPPPSP 407



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 58/209 (27%), Positives = 72/209 (34%), Gaps = 38/209 (18%)

Query: 21  PAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPA-KPAAP 79
           P +PP  +PP      P   P P  P+  P   +            P  P SP   P+A 
Sbjct: 400 PFSPPP-SPPVQAPFSPPASP-PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 457

Query: 80  EDPQMPAQPALPQL------PRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPP--- 130
             PQ P   A P L      P+ P  L        A P  +A    +P   F G+ P   
Sbjct: 458 PPPQAPPPLAAPPLQLAKPPPQAPPAL--------ATPPLQALP--SPPASFPGQAPFSP 507

Query: 131 -------PYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPP- 182
                  P A P P+A P+L  P  QVP    P+P A     A   P  P P    S P 
Sbjct: 508 SASLPMSPLATPPPQAPPVLAAPLLQVP----PSPPASPTLQAPRRPPTPGPDTSVSGPR 563

Query: 183 ----AGAAFPFPVYNGPMAGVPGPATVEH 207
                    P P    P + + GP    H
Sbjct: 564 LTLALAPGPPPPPSRSPSSTLSGPDLAGH 592



 Score = 36.2 bits (82), Expect = 0.034
 Identities = 53/189 (28%), Positives = 66/189 (34%), Gaps = 19/189 (10%)

Query: 5   SPICKQLREMLERWPLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGG-SGSDTKGGGS 63
           SP      +   R P P    S + P+    L  G P P  P+  P    SG D  G  S
Sbjct: 537 SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP--PSRSPSSTLSGPDLAGHSS 594

Query: 64  PATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHI 123
            AT          + PE     + P   +L           AA   GP    A  GAP  
Sbjct: 595 SATSTPEELRGYDSGPEGGAAASPPPDAELAAC------HPAAWSRGPAPPLAFRGAP-- 646

Query: 124 GFVGEPPPYAP-PDPKAAPLLYPPF-PQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSP 181
              G P P+ P   P +A  L   +  + P    PAP AL P P+   P      A    
Sbjct: 647 ---GAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPS---PGTSGGKAAAGA 700

Query: 182 PAGAAFPFP 190
            AGA+   P
Sbjct: 701 GAGASSRSP 709



 Score = 30.4 bits (67), Expect = 1.9
 Identities = 32/109 (29%), Positives = 40/109 (36%), Gaps = 10/109 (9%)

Query: 18  WPLPAAPPSRTPPQTLKHLPSGE-----PGPPFPAGMPGGGSGSDTKGGGSPATPEDPRS 72
           WP    P S     T+      E     PG   P   PG   G    G G+ A+    RS
Sbjct: 652 WPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGAS---SRS 708

Query: 73  PAKPAAPEDPQMPAQPALPQ--LPRRPRTLDEDGAAGEAGPVSKAAAGG 119
           P +    E P    Q ++ Q  L R       +GAAG +G     A GG
Sbjct: 709 PKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGG 757



 Score = 28.9 bits (63), Expect = 5.5
 Identities = 65/255 (25%), Positives = 82/255 (32%), Gaps = 66/255 (25%)

Query: 22  AAPPSRTPPQTLKHLPSGEPGPPFP-----------AGMPGGGSGSDTKGG-GSPATPED 69
           A  P+   P  L   P G P PP P           AG  G    ++  GG G    PE 
Sbjct: 14  ARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73

Query: 70  -PRS---------------PAKPAAPEDPQMPAQPALPQLPRRPRTLDEDG--------- 104
            PR+                A PA    P   + P       RP  L + G         
Sbjct: 74  APRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 133

Query: 105 AAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPP 164
           A G+A    K +A  A        P P   P P  A        +V +  +PAPSA   P
Sbjct: 134 ARGKATEAPKRSALSAGARRDTSGPTP-GTPSPAMARRSRAAGTEVGLP-RPAPSARPRP 191

Query: 165 P-----------AQLYPAAPTPPALFSPPAG-------------AAFPF--PVYNGPMA- 197
           P           ++     P+P A   P AG             +A P   P  +GP A 
Sbjct: 192 PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSAR 251

Query: 198 GVPGPATVEHRPLPK 212
           G P       +P PK
Sbjct: 252 GTPRAPAHPSQPKPK 266


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 72.8 bits (177), Expect = 3e-13
 Identities = 62/196 (31%), Positives = 72/196 (36%), Gaps = 21/196 (10%)

Query: 24   PPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQ 83
            PP+ TPP      P G P  P P G P   + +     GSPA    P+  + P A   P 
Sbjct: 988  PPAATPPS-----PKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPS 1042

Query: 84   MPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLL 143
                PA   LP+   T          G  +  +  GAP       PP   PP PK  P  
Sbjct: 1043 PKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAP------TPPAATPPSPKGGPAT 1096

Query: 144  YPP--FPQVPVVLQPAP-SALFPPPAQLYPAAP--TPPALFSPPAGAAFPFP--VYNGPM 196
              P   P  P    P+P   L  PP +  P  P  TPP   SP  G A P P      P 
Sbjct: 1097 PSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPP---SPKGGLATPPPKGAPTTPA 1153

Query: 197  AGVPGPATVEHRPLPK 212
            A  P P      P PK
Sbjct: 1154 ATPPSPKGGLATPPPK 1169



 Score = 71.6 bits (174), Expect = 7e-13
 Identities = 67/227 (29%), Positives = 80/227 (35%), Gaps = 27/227 (11%)

Query: 1    MGRTSPICKQLREMLERWPLPAAPPSR---TPPQTLKHLPSGEPGPPFPAGMPGGGSGSD 57
            +  TS   K+ R       +PA+P  +   TPP      P G P  P P   P   + + 
Sbjct: 911  LSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATP 970

Query: 58   TKGGGSPATPEDPRSPAKPAA--PEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKA 115
                G PATP    +P  PAA  P     PA P+    P  P             P  K 
Sbjct: 971  PSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAV---------TPPSPKG 1021

Query: 116  AAGGAPHIGFVGEPPPYAPPDPKAAPLLYP---PFPQVPVVLQPAPSALFPPPAQLYPAA 172
            +    P       PP   PP PK +P   P     P  P    P+P     P       A
Sbjct: 1022 SPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKG--GPATPSLKGA 1079

Query: 173  PTPPALF--SPPAGAAFPFP--VYNGPMAGVPGP----ATVEHRPLP 211
            PTPPA    SP  G A P P      P A  P P    AT  H+  P
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAP 1126



 Score = 69.7 bits (169), Expect = 3e-12
 Identities = 66/211 (31%), Positives = 78/211 (36%), Gaps = 34/211 (16%)

Query: 24   PPSRTPPQTLKHLPSGEPGPPFPAGMPGGG----SGSDTKGGGSPATPEDPRSPAKPAAP 79
            PP  TP  ++ +LP  + GP  PA          S S  K   +PA    P SP+   AP
Sbjct: 881  PPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAP 940

Query: 80   EDPQM--------PAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPP 131
              P          PA P+    P  P         G A P  K    GAP       PP 
Sbjct: 941  TPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPK----GAP------TPPA 990

Query: 132  YAPPDPKAAPLLYPP--FPQVPVVLQPAP-----SALFPPPAQLYPAAPTPPALFSPPAG 184
              PP PK  P    P   P  P V  P+P     +  FP  A   PAA TPP+    PA 
Sbjct: 991  ATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAA-TPPSPKGSPAA 1049

Query: 185  AAFPFPVYNGPMAGVP----GPATVEHRPLP 211
               P      P A +P    GPAT   +  P
Sbjct: 1050 TPLPKGAPTTPAATLPSPKGGPATPSLKGAP 1080



 Score = 64.7 bits (156), Expect = 9e-11
 Identities = 59/193 (30%), Positives = 68/193 (35%), Gaps = 25/193 (12%)

Query: 25   PSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAA--PEDP 82
            P+ TPP      P G    P P G P   + +     G  ATP    +P  PAA  P   
Sbjct: 1198 PAATPPS-----PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1252

Query: 83   QMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPL 142
              PA P     P  P         G A P  K    GAP+      P    PP PK  P 
Sbjct: 1253 GGPATPPPKGAPTPPAATPPSLKGGLATPPHK----GAPN------PAVVTPPSPKGGPA 1302

Query: 143  LYPP--FPQVPVVLQPAP--SALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGPMAG 198
              PP   P  P    P+P  S   PPP      APTPPA+  P        P       G
Sbjct: 1303 TSPPKGAPTPPAATPPSPKGSPGTPPP----KGAPTPPAVTPPSPKGTPTLPATTPSSKG 1358

Query: 199  VPGPATVEHRPLP 211
             P   + +  P P
Sbjct: 1359 GPTTPSSKEGPTP 1371



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 66/196 (33%), Positives = 71/196 (36%), Gaps = 23/196 (11%)

Query: 24   PPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAA-PEDP 82
            PP+ TPP      P G P  P P G P   + +     G  ATP    +P  PAA P  P
Sbjct: 1082 PPAATPPS-----PKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSP 1136

Query: 83   QMP-AQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPP---YAPPDPK 138
            +   A P     P  P         G A P  K    GAP       P P    A P PK
Sbjct: 1137 KGGLATPPPKGAPTTPAATPPSPKGGLATPPPK----GAPTTPAATPPSPKGGLATPSPK 1192

Query: 139  AAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFP--VYNGPM 196
             AP      P  P      PS   P  A   PAA TPP   SP  G A P P      P 
Sbjct: 1193 GAPTTPAATPPSPKGGLATPS---PKGAPTTPAA-TPP---SPKGGLATPSPKGAPTTPA 1245

Query: 197  AGVPGPATVEHRPLPK 212
            A  P P      P PK
Sbjct: 1246 ATPPSPKGGPATPPPK 1261



 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 61/204 (29%), Positives = 74/204 (36%), Gaps = 27/204 (13%)

Query: 19   PLPAAP--PSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKP 76
            P   AP  P+ TPP      P G    P P G P   + +     G  ATP    +P  P
Sbjct: 1144 PPKGAPTTPAATPPS-----PKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198

Query: 77   AA-PEDPQ----MPAQPALPQLPRRPRTLDEDGAA---GEAGPVSKAAAGGAPHIGFVGE 128
            AA P  P+     P+    P  P       + G A    +  P + AA   +P  G    
Sbjct: 1199 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATP 1258

Query: 129  PPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFP 188
            PP  AP  P A P      P +   L   P    P PA + P +P      SPP GA  P
Sbjct: 1259 PPKGAPTPPAATP------PSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTP 1312

Query: 189  FPVYNGPMAGVPGPATVEHRPLPK 212
                  P A  P P      P PK
Sbjct: 1313 ------PAATPPSPKGSPGTPPPK 1330



 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 60/232 (25%), Positives = 81/232 (34%), Gaps = 46/232 (19%)

Query: 24   PPSRTPPQ------TLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPA 77
            PP+ TPP       T  H  +  P    P    GG + S  KG  +P     P     P 
Sbjct: 1266 PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPG 1325

Query: 78   APEDPQMPAQPAL-PQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPD 136
             P     P  PA+ P  P+   TL     + + GP + ++          G  PP A P 
Sbjct: 1326 TPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSK--------EGPTPPAATPS 1377

Query: 137  PKAAPLLYPPFPQ-----------------VPVVLQPAPS-------ALFPPPAQLYPAA 172
             K  P + PP P+                 +P+  + AP+       A  P    L P A
Sbjct: 1378 HKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPA 1437

Query: 173  PTP------PALFSPPAGAAFPFPVYNGPMAGVPGPATVEHRPLPKDYMMES 218
             TP      PA  +P  G A P    +  +  V  P+  E  P PK     S
Sbjct: 1438 VTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE-PPAPKQVATSS 1488



 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 55/192 (28%), Positives = 68/192 (35%), Gaps = 17/192 (8%)

Query: 25   PSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQM 84
            P+ TPP      P G    P P G P   + +     G PATP    +P  PAA   P +
Sbjct: 1221 PAATPPS-----PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAA-TPPSL 1274

Query: 85   PAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLY 144
                A P     P        + + GP + +   GAP       PP   PP PK +P   
Sbjct: 1275 KGGLATPPHKGAPNPAVVTPPSPKGGPAT-SPPKGAP------TPPAATPPSPKGSPGTP 1327

Query: 145  PP--FPQVPVVLQPAP--SALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVP 200
            PP   P  P V  P+P  +   P         PT P+    P   A       GP    P
Sbjct: 1328 PPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPP 1387

Query: 201  GPATVEHRPLPK 212
             P      P PK
Sbjct: 1388 SPKRGPAIPSPK 1399



 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 65/232 (28%), Positives = 83/232 (35%), Gaps = 49/232 (21%)

Query: 20   LPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAP 79
            LPA  PS     T    PS + GP  PA  P        KGG +   P   R PA P+  
Sbjct: 1349 LPATTPSSKGGPTT---PSSKEGPTPPAATPSH------KGGPAMTPPSPKRGPAIPSPK 1399

Query: 80   EDPQMPAQPALPQLPRR-PRT-LDEDGAAG----------------EAGPVSKAAAGGA- 120
             DP  PA   +P  P++ P T +  +GAA                 +  P + A  GG  
Sbjct: 1400 GDPTSPA--VIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPA 1457

Query: 121  -------PHIGFVGEPPPYAPP---------DPKAAPLLYPPF--PQVPVVLQPAPSAL- 161
                   P +  V  P P  PP          PK AP    P   P +P V+  +P  + 
Sbjct: 1458 TPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVP 1517

Query: 162  FPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVPGPATVEHRPLPKD 213
              P ++  P APT   L         P      P   VP P      P PK+
Sbjct: 1518 ATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE 1569



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 56/199 (28%), Positives = 71/199 (35%), Gaps = 27/199 (13%)

Query: 41   PGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPA---------KPAAPEDPQMPAQPALP 91
            P PP P G P   + +     G    P++  +P+          PA P   Q PA     
Sbjct: 856  PTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTS 915

Query: 92   QLPRRPRTLDED-----GAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYPP 146
              P++ R            + +  P   AA   +P  G     P +AP  P A P     
Sbjct: 916  SSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKG 975

Query: 147  FPQVPVVL-QPAPSALFPPPAQLYPA------APTPPALFSP-----PAGAAFPFPVYNG 194
             P  P     P P A  PP  +  PA      APTPPA+  P     PA   FP      
Sbjct: 976  GPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTP 1035

Query: 195  PMAGVPGP-ATVEHRPLPK 212
            P A  P P  +    PLPK
Sbjct: 1036 PAATPPSPKGSPAATPLPK 1054



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 60/247 (24%), Positives = 91/247 (36%), Gaps = 36/247 (14%)

Query: 2    GRTSPICKQLREMLERWPLPAAPPSRTPPQTLKH--LPSGEPGPPFPAGMPGG------- 52
            G T+P  K+        P     P+ TPP   +   +PS +  P  PA +P         
Sbjct: 1359 GPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT 1418

Query: 53   -----GSGSDTKGG------------GSPATPEDPRSPAKPAAPEDPQMPA-QPALPQLP 94
                 G+ + +KG              +PAT      PA P++  DP +PA  P  P+ P
Sbjct: 1419 PVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEP 1478

Query: 95   RRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKA-----APLLYPPFPQ 149
              P+ +    +  +A P + A  G       +   P   P  P +     AP       +
Sbjct: 1479 PAPKQVATSSSPKKA-PATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKK 1537

Query: 150  VPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVPGPATVEHRP 209
             P  L  AP     PPA   P+    PA+ +P    A P          V  P+T +  P
Sbjct: 1538 TPATL--APKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVT-PSTYKGAP 1594

Query: 210  LPKDYMM 216
             PK+ ++
Sbjct: 1595 SPKELLI 1601



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 59/209 (28%), Positives = 73/209 (34%), Gaps = 41/209 (19%)

Query: 20   LPAA-PPSRTPPQTLKHL-----PSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSP 73
            LPA  PPS   P   K +     P   P  P P G P   +   +     PATP   R P
Sbjct: 1467 LPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDP 1526

Query: 74   AKPAA------------PEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAP 121
              P A            P++  +P    +P   + P       A   A P SK A+    
Sbjct: 1527 IAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAP--ATPSSKEASS--- 1581

Query: 122  HIGFVGEPPPYAPPDPKAAP----LLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPA 177
                   PP   P   K AP    LL PP      V  P+P     PPA   P+    PA
Sbjct: 1582 -------PPAVTPSTYKGAPSPKELLIPP-----AVTSPSPKEAPTPPAVTPPSPEKGPA 1629

Query: 178  LFSPPAGAAFPFPVYNGPMAGVP-GPATV 205
              +P      P PV    +   P  PA+V
Sbjct: 1630 TPAPKGTPTSP-PVTPSSLKDSPTSPASV 1657



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 60/226 (26%), Positives = 76/226 (33%), Gaps = 51/226 (22%)

Query: 19  PLPAAPPSRTPPQTLK-----HLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSP 73
           P P+ PP+ TPP T K     H  +  P    P   P   SG+               SP
Sbjct: 735 PSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSP 794

Query: 74  AKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGE-------AGPVSKAAAGGAPH--IG 124
           +       PQ           +RP T  + G+AG        + PVS   A   P   + 
Sbjct: 795 SPLGVSVSPQ----------TKRPPT--KKGSAGPDTPIGNLSSPVSPVEASFLPENSLS 842

Query: 125 FVGE------------PPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAA 172
           F G             P P   P P A   L P    +P    P PS +  P  +  PA 
Sbjct: 843 FQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPAT 902

Query: 173 PTP---PAL----FSPPAGAAFPFPVYNGPMAGVPGPATVEHRPLP 211
           P P   PAL     SP    A P P       G+P   + +  P P
Sbjct: 903 PAPKQAPALSMTSSSPKKARATPAP------KGIPASPSPKGAPTP 942



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 50/216 (23%), Positives = 78/216 (36%), Gaps = 31/216 (14%)

Query: 25   PSRTPPQTLKHL---PSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPED 81
            P++  P  LK +   P+ E  P   A    G     +     P  P DP +      P  
Sbjct: 1673 PAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICP-DPSAKNGSKGPLS 1731

Query: 82   PQMPAQPALPQLPRRPRTLD-EDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAA 140
               PA P LP      +T   +D +    GP++   +  +  +           P P++A
Sbjct: 1732 TVAPA-PLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVL--PKPESA 1788

Query: 141  PLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAP-----TPPALFSP-------------P 182
             +   P P V + L P+P    PP  Q  P++P     +P    +P             P
Sbjct: 1789 SVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEP 1848

Query: 183  AGAAFPFP--VYNGP---MAGVPGPATVEHRPLPKD 213
                 PF   + N P    AG+P P     +P+ K+
Sbjct: 1849 ISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKN 1884


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 71.2 bits (173), Expect = 1e-12
 Identities = 66/207 (31%), Positives = 72/207 (34%), Gaps = 39/207 (18%)

Query: 16  ERWPLPAAPPSRTPP----QTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPR 71
           +R+P PA P    PP    QT    P G PGPP P G P  G        G P   + P 
Sbjct: 215 DRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPP 274

Query: 72  SPAK-PAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPP 130
            P   P  P       QP L  LP               GP       G P     G PP
Sbjct: 275 PPVLFPGQPF-----GQPPLGPLP--------------PGPPPPVPGYGPPP----GPPP 311

Query: 131 PYAPPDPKAAPLLYPPFPQ----VPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAA 186
           P   P P   P  +PP P      P+ L P P    PPP    PA    PA F PP  + 
Sbjct: 312 PQQGPPPPPGP--FPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSG 369

Query: 187 FPFPVYNGPMAGVPGPATVEHRPLPKD 213
            P     G     P P     RP P D
Sbjct: 370 MPTSDSRG-----PPPTDPYGRPPPYD 391



 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 73/224 (32%), Positives = 82/224 (36%), Gaps = 36/224 (16%)

Query: 9   KQLREMLERWPLPAAPPSRTP----------PQTLKHLPSGEPGPPFPAGMPGGGS---- 54
           K+L ++L +  L    P  TP           Q+ K   SG+      AG PGG S    
Sbjct: 138 KKLMDLLPKRELHGQNPVVTPCNKQFLSQFEMQSRKTTQSGQMSGEGKAGPPGGSSRAAF 197

Query: 55  --GSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGP- 111
             G   +G    A P   R P  PA P  P  P  PA    PR P  L   G  G  GP 
Sbjct: 198 PQGGRGRGRFPGAVPGGDRFPG-PAGPGGPP-PPFPAGQTPPRPP--LGPPGPPGPPGPP 253

Query: 112 ----VSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLL--YPPFPQVPV------VLQPAPS 159
               V      G P+ G    PP   P  P   P L   PP P  PV         P P 
Sbjct: 254 PPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQ 313

Query: 160 ALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVPGPA 203
              PPP   +P  P PP    PP   A P P   GP  G P PA
Sbjct: 314 QGPPPPPGPFP--PRPPGPLGPPLTLA-PPPHLPGPPPGAPPPA 354


>gi|21389357 MAPK-interacting and spindle-stabilizing protein [Homo
           sapiens]
          Length = 245

 Score = 69.7 bits (169), Expect = 3e-12
 Identities = 68/195 (34%), Positives = 78/195 (40%), Gaps = 24/195 (12%)

Query: 21  PAAPPSRTP--PQTLKHLPSGEP-GPPF--PAGMPGGGSGSDTKGGGSPATPEDPRSPAK 75
           P+A PS  P  P      PS  P GPP   PA  P  G      GG  PA       P  
Sbjct: 55  PSATPSTVPFGPAPTGMYPSVPPTGPPPGPPAPFPPSGPSCPPPGGPYPAPTVPGPGPTG 114

Query: 76  PAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGG-APHIGFVGEPPPYAP 134
           P     P MP     P+LPR      +  AAG  GP    ++G  AP +G  G+ P    
Sbjct: 115 PYPT--PNMP----FPELPRPYGAPTDPAAAGPLGPWGSMSSGPWAPGMG--GQYPTPNM 166

Query: 135 PDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPA---APT----PPALFSPPAGAAF 187
           P P   P   PP PQ P    P P    PP A   PA   APT     P L+  P+    
Sbjct: 167 PYPSPGPYPAPPPPQAPGAAPPVPWGTVPPGAWGPPAPYPAPTGSYPTPGLYPTPSN--- 223

Query: 188 PFPVYNGPMAGVPGP 202
           PF V +GP    P P
Sbjct: 224 PFQVPSGPSGAPPMP 238



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 53/205 (25%), Positives = 76/205 (37%), Gaps = 43/205 (20%)

Query: 14  MLERWPLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSP 73
           M + + L  A P  +P +T   + + +PG P P G PG    ++      P+ P    S 
Sbjct: 1   MSDEFSLADALPEHSPAKT-SAVSNTKPGQP-PQGWPGSNPWNN------PSAPSSVPSG 52

Query: 74  AKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYA 133
             P+A                  P T+          P   A  G  P +   G PP   
Sbjct: 53  LPPSAT-----------------PSTV----------PFGPAPTGMYPSVPPTGPPPGPP 85

Query: 134 PPDPKAAPLLYP---PFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFP 190
            P P + P   P   P+P  P V  P P+  +P P   +P  P P    + PA A    P
Sbjct: 86  APFPPSGPSCPPPGGPYP-APTVPGPGPTGPYPTPNMPFPELPRPYGAPTDPAAAGPLGP 144

Query: 191 ---VYNGPMA-GVPGPATVEHRPLP 211
              + +GP A G+ G     + P P
Sbjct: 145 WGSMSSGPWAPGMGGQYPTPNMPYP 169



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 35/103 (33%), Positives = 44/103 (42%), Gaps = 14/103 (13%)

Query: 119 GAPHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVV-LQPAPSALFP-------PPAQLYP 170
           G P  G+ G  P   P  P + P   PP      V   PAP+ ++P       PP    P
Sbjct: 28  GQPPQGWPGSNPWNNPSAPSSVPSGLPPSATPSTVPFGPAPTGMYPSVPPTGPPPG---P 84

Query: 171 AAPTPPALFS-PPAGAAFPFPVYNGPMAGVPGPATVEHRPLPK 212
            AP PP+  S PP G  +P P   GP  G  GP    + P P+
Sbjct: 85  PAPFPPSGPSCPPPGGPYPAPTVPGP--GPTGPYPTPNMPFPE 125



 Score = 31.6 bits (70), Expect = 0.84
 Identities = 25/75 (33%), Positives = 32/75 (42%), Gaps = 11/75 (14%)

Query: 19  PLPAAPPSRTP----PQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDP-RSP 73
           P PA PP + P    P     +P G  GPP P   P G   +     G   TP +P + P
Sbjct: 173 PYPAPPPPQAPGAAPPVPWGTVPPGAWGPPAPYPAPTGSYPTP----GLYPTPSNPFQVP 228

Query: 74  AKPAAPEDPQMPAQP 88
           + P+    P MP  P
Sbjct: 229 SGPSGA--PPMPGGP 241


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 65/225 (28%), Positives = 89/225 (39%), Gaps = 13/225 (5%)

Query: 19  PLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGS--GSDTKGGGSPATP---EDPRSP 73
           PLP +         L   P  EPGPP PAG+    +    D  G  +P +    E  +S 
Sbjct: 576 PLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSS 635

Query: 74  AKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYA 133
            +     D +MP+ P       +P  +    AA  A  V        P  GF   PPP  
Sbjct: 636 GEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPP 695

Query: 134 PPDPKAAPLLYPPFPQVPVVLQPAPSALF--PPPAQLYPAAPTPPALFSPPAGAAFPFPV 191
           PP P+    + PP P  P    PA  A+   PPP    P  P PP L   P      FPV
Sbjct: 696 PPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPV 755

Query: 192 YNGPMAGVPGPATVEHRPLPKDYMMESVLVTLFCCLLTGLIAIVY 236
               M+ V G    +   +P  + M++ +++    L+TG  A  Y
Sbjct: 756 MQVDMSHVLGG---QWGGMPMSFQMQTQVLSR---LMTGQGACPY 794



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 60/206 (29%), Positives = 74/206 (35%), Gaps = 53/206 (25%)

Query: 19   PLPAAPPSRTPPQ--TLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRS-PAK 75
            PL    P  TP    +L    S E  P  P G P    GS      SP  P  P S PA 
Sbjct: 1311 PLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAP 1370

Query: 76   PAAPEDPQMPAQPA-----------------LPQLPRRPRTLDEDGAAGEAGPVSKAAAG 118
              +     +P  P                  LP  P      DE      +GP++     
Sbjct: 1371 SPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDE-----RSGPLA----- 1420

Query: 119  GAPHIGFVGEPPPYAPPDPKAAPLLYP---------PFPQVPVVLQPAPSALFPPPAQLY 169
             +P +   G P P   P P   PL  P         P P  P++  PAP A  PPP +  
Sbjct: 1421 -SPVLLETGLPLPL--PLPLPLPLALPAVLRAQARAPTPLPPLL--PAPLASCPPPMKRK 1475

Query: 170  PAAP--TPPALFS-------PPAGAA 186
            P  P  +PP++ S       PPAGAA
Sbjct: 1476 PGRPRRSPPSMLSLDGPLVRPPAGAA 1501



 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 52/192 (27%), Positives = 67/192 (34%), Gaps = 35/192 (18%)

Query: 21  PAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSP---AKPA 77
           PA PP        K  P   PGPP P        G     G SP   + P +P   + PA
Sbjct: 432 PAPPPLPPAEPLAKEKPGTPPGPP-PPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPA 490

Query: 78  APEDPQMPAQPALPQLPRRPRTL-------DEDGAAG-EAGPVSKAAAGGAP-------- 121
            PE P       +  L +  RT        D D     E  P+S +++  +P        
Sbjct: 491 GPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNS 550

Query: 122 HIGFVGEPPPYAPPDPKAAPLLYP-PFP------QVPVVLQPAPSALFPPPAQLYPAAPT 174
             GF G  PP + P       + P P P      ++ + L P P    PP     P  P 
Sbjct: 551 QPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRP----PPE----PGPPD 602

Query: 175 PPALFSPPAGAA 186
           P  L S  A  A
Sbjct: 603 PAGLLSQTAEVA 614



 Score = 37.0 bits (84), Expect = 0.020
 Identities = 54/220 (24%), Positives = 78/220 (35%), Gaps = 44/220 (20%)

Query: 23   APPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPED- 81
            A P  +P +  +H    EP PP    +P        +    P  P  PR P+ P  PE  
Sbjct: 1250 ARPPLSPERAPEHDLEVEPEPPMMLPLP-------LQPPLPP--PRPPRPPSPPPEPETT 1300

Query: 82   ----PQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDP 137
                P +P +P     P     L    A  ++     A  GG P +         + P  
Sbjct: 1301 DASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQV 1360

Query: 138  KAAPLLYP-PFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAF----PFPV- 191
              +P  YP P P +      +   L   P + +   PT    FS P+G       P P  
Sbjct: 1361 PGSPFSYPAPSPSL------SSGGLPRTPGRDFSFTPT----FSEPSGPLLLPVCPLPTG 1410

Query: 192  ----YNGPMA-------GVPGPATVEHRPLPKDYMMESVL 220
                 +GP+A       G+P P  +   PLP    + +VL
Sbjct: 1411 RRDERSGPLASPVLLETGLPLPLPL---PLPLPLALPAVL 1447



 Score = 32.3 bits (72), Expect = 0.50
 Identities = 49/208 (23%), Positives = 67/208 (32%), Gaps = 33/208 (15%)

Query: 19  PLPAAPPSRTPPQT-LKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPA 77
           P P    + +P QT + H P   P P  P      G+    +   +PA P  P  PA+P 
Sbjct: 389 PAPGFKSAFSPYQTPVAHFP---PPPEEPTATAAFGARDSGEFRRAPAPP--PLPPAEPL 443

Query: 78  APEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDP 137
           A E P  P  P  P       +++  G            + G P +    E  P  P  P
Sbjct: 444 AKEKPGTPPGPPPPD----TNSMELGGRPTFGWSPEPCDSPGTPTL----ESSPAGPEKP 495

Query: 138 --------------KAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPA 183
                         +   LL+   P     LQ   S +    +QL P AP     F   +
Sbjct: 496 HDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAP-----FGTNS 550

Query: 184 GAAFPFPVYNGPMAGVPGPATVEHRPLP 211
              F  P          G   +   PLP
Sbjct: 551 QPGFRGPTPPSSRPSSTGLEDISPTPLP 578



 Score = 30.4 bits (67), Expect = 1.9
 Identities = 37/128 (28%), Positives = 51/128 (39%), Gaps = 18/128 (14%)

Query: 62   GSPATP-----EDPRSPAKPAAPED-PQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKA 115
            G+PA       E+     +  APE+ P M  +P LP     P   D      E G   + 
Sbjct: 1178 GAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPA--DSREPPEEPGLSQEG 1235

Query: 116  AAGGAPHIGFVGEPPPYAPPDPKAAPLLYPP-FPQVPVVLQPAPSALFPPPAQLYPAAPT 174
            A   +P      EPP     + +A P L P   P+  + ++P P  + P P Q     P 
Sbjct: 1236 AMLLSP------EPPA---KEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPR 1286

Query: 175  PPALFSPP 182
            PP   SPP
Sbjct: 1287 PPRPPSPP 1294



 Score = 29.6 bits (65), Expect = 3.2
 Identities = 37/132 (28%), Positives = 48/132 (36%), Gaps = 30/132 (22%)

Query: 65   ATPEDPRSPAKPAAPEDPQMPAQ-----PALPQLPRRPRTLDEDGAAGEAGPVSKAAAGG 119
            A P   R+ A+   P  P +PA      P + + P RPR       + + GP+ +  AG 
Sbjct: 1442 ALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLD-GPLVRPPAGA 1500

Query: 120  APHIGFVGEPPPYAPPDPKAAPLLYPPFPQV----PVVLQ------PAPSALFPPPAQLY 169
            A     +G      P  P+      P FP       V L       PAP    PPP    
Sbjct: 1501 A-----LGRELLLLPGQPQT-----PVFPSTHDPRTVTLDFRNAGIPAP----PPPLPPQ 1546

Query: 170  PAAPTPPALFSP 181
            P  P PP    P
Sbjct: 1547 PPPPPPPPPVEP 1558



 Score = 28.1 bits (61), Expect = 9.3
 Identities = 38/160 (23%), Positives = 50/160 (31%), Gaps = 46/160 (28%)

Query: 18  WPLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPA 77
           +P+P   P   PP    H     P PP PA                P  P  P  P  P 
Sbjct: 703 FPMPPPLPPPPPPPPPAHPAVTVPPPPLPA---------------PPGVPPPPILPPLPP 747

Query: 78  APE--------------DPQMPAQPALPQLPRR--PRTLDEDGAAGEAGPVSKAAAGGAP 121
            P                 Q    P   Q+  +   R +   GA      ++ AAA  + 
Sbjct: 748 FPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQGACPYPPFMAAAAAAASA 807

Query: 122 HIGFVGEPP---PYA------------PPDPKAAPLLYPP 146
            + FV  PP   P++            PP PK  P + PP
Sbjct: 808 GLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKFDPSVPPP 847



 Score = 28.1 bits (61), Expect = 9.3
 Identities = 26/92 (28%), Positives = 34/92 (36%), Gaps = 3/92 (3%)

Query: 128  EPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAF 187
            EPP       + A LL P  P   V  +P  S    P   L    P PP +   P     
Sbjct: 1224 EPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDL-EVEPEPPMMLPLPLQPPL 1282

Query: 188  PFPVYNGPMAGVPGPATVE--HRPLPKDYMME 217
            P P    P +  P P T +  H  +P + + E
Sbjct: 1283 PPPRPPRPPSPPPEPETTDASHPSVPPEPLAE 1314


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 1691

 Score = 65.1 bits (157), Expect = 7e-11
 Identities = 63/208 (30%), Positives = 73/208 (35%), Gaps = 29/208 (13%)

Query: 21  PAAPPSRTPPQTLKHLP----SGEPGPPFPAGMPG--GGSGSDTKGGGSPATPEDPRSPA 74
           P  PP   PP  +        +G PG P   G+PG  G  G      G P  P +P    
Sbjct: 619 PMGPPGFGPPGPVGEKGIQGVAGNPGQP---GIPGPKGDPGQTITQPGKPGLPGNPGRDG 675

Query: 75  KPAAPEDPQMPAQPALPQLP--RRPRTLDEDGAAGEAGPVSKAAAGGAP-------HIGF 125
               P DP +P QP LP +P  +    +   G  G  GP       G P        IG 
Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735

Query: 126 VGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPP------ALF 179
            G P P   P PK  P    P P  P  L     AL P   + +P  P PP       L 
Sbjct: 736 EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP 795

Query: 180 SP-----PAGAAFPFPVYNGPMAGVPGP 202
            P     P G   P      P  GV GP
Sbjct: 796 GPKGDVGPNGQPGPMGPPGLPGIGVQGP 823



 Score = 55.1 bits (131), Expect = 7e-08
 Identities = 58/194 (29%), Positives = 68/194 (35%), Gaps = 22/194 (11%)

Query: 37   PSGEPGPPFPAGMPG-GGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMP---------A 86
            P GEPG P   G PG  GS  D    G P  P  P +  +P  P  P  P          
Sbjct: 1081 PKGEPGLPGYPGNPGIKGSVGDP---GLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISG 1137

Query: 87   QPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHI----GFVGEP--PPYAPPDPKAA 140
             P  P LP  P  +   G  G+ GP  +    G   I    G  GEP  P +  P P   
Sbjct: 1138 PPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGL 1197

Query: 141  PLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVP 200
            P L        +   P    L  P  +  P     P +  PP     P P   GP  G P
Sbjct: 1198 PGLSGQKGDGGLPGIPGNPGLPGPKGE--PGFHGFPGVQGPPGPPGSPGPALEGP-KGNP 1254

Query: 201  GPATVEHRPLPKDY 214
            GP     RP P  +
Sbjct: 1255 GPQGPPGRPGPTGF 1268



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 42/135 (31%), Positives = 48/135 (35%), Gaps = 22/135 (16%)

Query: 19   PLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGG-GSPATP---------E 68
            P P  PP R  P   +    G PGP  P G+PG G     KG  G P  P          
Sbjct: 1254 PGPQGPPGRPGPTGFQ----GLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQG 1309

Query: 69   DPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGE 128
             P     P  P    M   P LP +P  P      G  G AGP       G P  G +G 
Sbjct: 1310 PPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGP------EGEP--GLIGP 1361

Query: 129  PPPYAPPDPKAAPLL 143
            P P   P P    ++
Sbjct: 1362 PGPPGLPGPSGQSII 1376



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 60/201 (29%), Positives = 67/201 (33%), Gaps = 34/201 (16%)

Query: 37   PSGEPGPPFPAGMPG-----GGSGSDTKG-------GGSPATPEDPRSPAKPAAPEDPQM 84
            PSG PG P   G+PG     G  G  + G        G P  P  P +P    +  DP +
Sbjct: 1046 PSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGL 1105

Query: 85   PAQPAL------PQLPRRPRTLDEDGAAGEAGPVSKAAAGGAP-HIGFVGEPPPYAPPDP 137
            P  P        P LP  P T    G  G +GP       G P  +G  G P    PP  
Sbjct: 1106 PGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGE 1165

Query: 138  KA--------APLLYPPFPQVPVVLQPAPSALFPPPAQL----YPAAPTPPALFSPPAGA 185
            K          P      P  P    P P  L     Q      P  P  P L  P    
Sbjct: 1166 KGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEP 1225

Query: 186  AF-PFPVYNGPMA--GVPGPA 203
             F  FP   GP    G PGPA
Sbjct: 1226 GFHGFPGVQGPPGPPGSPGPA 1246



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 59/214 (27%), Positives = 69/214 (32%), Gaps = 33/214 (15%)

Query: 19   PLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPG-----------GGSGSDTKG-GGSPAT 66
            P P  PP    P      P G PG P P G PG           G  G D  G  G   +
Sbjct: 807  PGPMGPPGL--PGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGS 864

Query: 67   PEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHI--- 123
            P  P +P     P  P +P +      P     +   G  G  GP+      G P +   
Sbjct: 865  PGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924

Query: 124  ----GFVGEPPPYAPPDPKAAP-LLYPPFPQVPVVL-------QPA----PSALFPPPAQ 167
                G  G P P      K  P L  PP P  P +L       +P     P    P   Q
Sbjct: 925  DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQ 984

Query: 168  LYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVPG 201
              P  P  P L   P     P P  N  + G PG
Sbjct: 985  GLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPG 1018



 Score = 52.0 bits (123), Expect = 6e-07
 Identities = 50/178 (28%), Positives = 58/178 (32%), Gaps = 20/178 (11%)

Query: 39  GEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPR 98
           G PG P P G PG        G   P  P+  R P     P  P  P  P LP +P    
Sbjct: 60  GLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGP-----PGLPGFPGTPGLPGMP---- 110

Query: 99  TLDEDGAAGEAG-PVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPA 157
               DGA G  G P      G     G  G P    PP P   P +      + +   P 
Sbjct: 111 --GHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPG 168

Query: 158 PSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVPGPATVEHRPLPKDYM 215
           P           P  P PP +   P     P P+      G+ GP      P PK  M
Sbjct: 169 PKG--------NPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNM 218



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 57/185 (30%), Positives = 69/185 (37%), Gaps = 27/185 (14%)

Query: 18  WPLPAAPPSRTPPQTLKHL-----PSGEPGPPFPAGMPG-GGSGSDTKGG-----GSPAT 66
           +P P  PP RT    L        P+G+PGP  P G+PG G  G     G     G P  
Sbjct: 779 FPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGL 838

Query: 67  PEDPRSPAKPAAP--EDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIG 124
              P     P  P  + P  P +   P +P  P  +   G+ G  G   KA A G P  G
Sbjct: 839 HGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPG---KAGASGFP--G 893

Query: 125 FVGEPPPYAPPDPKAAPLLYPPFPQVPVV-----LQPAPSALFP---PPAQLYPAAPTPP 176
             GE     PP P   PL  P    VP +     LQ  P    P     ++  P  P PP
Sbjct: 894 TKGEMGMMGPPGP-PGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPP 952

Query: 177 ALFSP 181
               P
Sbjct: 953 GPMDP 957



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 62/227 (27%), Positives = 74/227 (32%), Gaps = 60/227 (26%)

Query: 39   GEPGPPFP--------------AGMPGGGSGSDTKG-------GGSPATPEDPRSPAKPA 77
            G PGPP P               G+PG    S  KG        G P     P  P  P 
Sbjct: 947  GLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPG 1006

Query: 78   APEDPQMPAQPALPQLPRRPRTLDEDGAAGEAG-------------PVSKAAAG-----G 119
               +P +P QP L   P    T+ + G  G  G             P S    G     G
Sbjct: 1007 PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG 1066

Query: 120  APHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVV-----------LQPAPSALFPPPAQL 168
             P I  +G P     P PK  P L P +P  P +           L   P A   P    
Sbjct: 1067 DPGISSIGLP---GLPGPKGEPGL-PGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPG 1122

Query: 169  YPAAPTPP---ALFSPPAGAAF---PFPVYNGPMAGVPGPATVEHRP 209
            +P  P PP    +  PP        P PV  G   G PGP   + +P
Sbjct: 1123 FPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKP 1169



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 55/199 (27%), Positives = 65/199 (32%), Gaps = 42/199 (21%)

Query: 39  GEPGPPFPAGMPG--GGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRR 96
           G PGPP   G PG  GG   +    G P     P    +   P  P +P  P  P  P R
Sbjct: 267 GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326

Query: 97  PRTLDEDGAAGEAGP----VSKAAAG---------GAPHI-------GFVGEPPPYAPPD 136
                + G  G  GP    + +   G         G P +       GF G   P   P 
Sbjct: 327 DGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPG 386

Query: 137 PKAAPLLYPPFPQ-------------VPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPA 183
           P  A ++ PP P               P +  P P  L   P    P  P PP     PA
Sbjct: 387 PPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGA--PGLPGPPG----PA 440

Query: 184 GAAFPFPVYNGPMAGVPGP 202
           G   P P       G PGP
Sbjct: 441 GPHIP-PSDEICEPGPPGP 458



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 52/199 (26%), Positives = 63/199 (31%), Gaps = 42/199 (21%)

Query: 39  GEPGPPFPAGM----PGGGSGSDTKGG-GSPATPEDPRSPAKPAAPEDPQMPAQPALPQL 93
           G+ GPP P G+    PG G     KG  G P  P +      P     P +P  P    +
Sbjct: 334 GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM 393

Query: 94  --PRRPRTLDEDGAAGEAGPVSKAAAG--------GAPHIGFVGEPPPYAPPDPKAAPLL 143
             P  P    E G  G+ GP   +  G        GAP  G  G P P  P  P +  + 
Sbjct: 394 GPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAP--GLPGPPGPAGPHIPPSDEIC 451

Query: 144 YPPFPQVP--------------------VVLQPAPSALFPPPAQLYPAAPTPPALFSPPA 183
            P  P  P                           + +  PP Q     P  P L  PP 
Sbjct: 452 EPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ-----PGLPGLPGPPG 506

Query: 184 GAAFPFPVYNGPMAGVPGP 202
              FP        AG  GP
Sbjct: 507 SLGFPGQKGEKGQAGATGP 525



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 62/200 (31%), Positives = 68/200 (34%), Gaps = 31/200 (15%)

Query: 21  PAAPPSRTPPQTL-KHLPSG----EPGPPFPAGMPG--GGSGSDTKGGGSPATPEDPRSP 73
           P AP    PP     H+P      EPGPP P G PG  G  G      G      D    
Sbjct: 428 PGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQ----GVKGDKGDTCFN 483

Query: 74  AKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYA 133
                   P  P QP LP LP  P +L   G  GE G        G P  G  G P    
Sbjct: 484 CIGTGISGP--PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP--GIPGAPGAPG 539

Query: 134 PPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAP-TP-----PALFSP---PAG 184
            P  K  P     FP     ++     L  P A   P  P TP     P L  P   P G
Sbjct: 540 FPGSKGEPGDILTFPG----MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGG 595

Query: 185 AAFP---FPVYNGPMAGVPG 201
             F     P  N  + G+PG
Sbjct: 596 ITFKGERGPPGNPGLPGLPG 615



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 63/209 (30%), Positives = 70/209 (33%), Gaps = 33/209 (15%)

Query: 25   PSRTPPQTLKHLPS--GEPGPPFPAGMPG----GGSG-------SDTKG-GGSPATPEDP 70
            P +  P   K  P   G PGP    G PG    G  G       S  KG GG P  P +P
Sbjct: 1157 PGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNP 1216

Query: 71   RSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPP 130
              P     P     P     P  P  P    E G  G  GP  +   G     GF G P 
Sbjct: 1217 GLPGPKGEPGFHGFPGVQGPPGPPGSPGPALE-GPKGNPGP--QGPPGRPGPTGFQGLPG 1273

Query: 131  PYAPP---------DPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSP 181
            P  PP           K  P   P  P +P +         PP  Q  P  P    +   
Sbjct: 1274 PEGPPGLPGNGGIKGEKGNP-GQPGLPGLPGL----KGDQGPPGLQGNPGRPGLNGMKGD 1328

Query: 182  PAGAAFP-FPVYNGPMAGVPGPATVEHRP 209
            P     P FP   GP +GVPG A  E  P
Sbjct: 1329 PGLPGVPGFPGMKGP-SGVPGSAGPEGEP 1356



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 39/110 (35%), Positives = 42/110 (38%), Gaps = 12/110 (10%)

Query: 37   PSGEPG---PPFPAGMPG-GGSGSDTKG-GGSPATPEDPRSPAKPAAPEDPQ-MPAQPAL 90
            P GEPG   PP P G+PG  G     KG  G P  P  P     P  P+ PQ +P     
Sbjct: 1352 PEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLP-GPQGPQGLPGPTGP 1410

Query: 91   PQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPP---YAPPDP 137
            P  P R      DGA G  G        G    G  G P P     PP P
Sbjct: 1411 PGDPGRNGLPGFDGAGGRKGDPGLPGQPGTR--GLDGPPGPDGLQGPPGP 1458



 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 54/195 (27%), Positives = 63/195 (32%), Gaps = 22/195 (11%)

Query: 21  PAAPPSRTPPQTLKHLPS-----GEPGPPFPAGMPG--GGSGSDTKGGGSPATPEDPRSP 73
           P  P S+  P  +   P      GE G P   G+PG  G  G D    G P  P     P
Sbjct: 538 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQD----GLPGLPGPKGEP 593

Query: 74  AKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPV-SKAAAGGAPHIGFVGEPPPY 132
                  +   P  P LP LP     +   G  G  GPV  K   G A + G  G P P 
Sbjct: 594 GGITFKGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGPVGEKGIQGVAGNPGQPGIPGPK 652

Query: 133 APPDPKAAPLLYPPFPQVP-----VVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAF 187
             P         P  P  P     V L   P     P     P +   P +     G   
Sbjct: 653 GDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGI----PGIGL 708

Query: 188 PFPVYNGPMAGVPGP 202
           P P       G+PGP
Sbjct: 709 PGPPGPKGFPGIPGP 723



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 36/119 (30%), Positives = 44/119 (36%), Gaps = 11/119 (9%)

Query: 37  PSGEPGPPFPAGMPG--GGSGSDTKGG--GSPATPEDPRSPAKPAAPEDPQMPAQPALPQ 92
           P G PG P   G+PG  G  G+    G  G   T  +   P  P  P     P  P +P 
Sbjct: 94  PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPG 153

Query: 93  LPRRPRTL---DEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYPPFP 148
           +   P ++      G  G  G        G P  G  G P P  PP P    L+ PP P
Sbjct: 154 MKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLP--GPTGIPGPIGPPGPPG--LMGPPGP 208



 Score = 37.0 bits (84), Expect = 0.020
 Identities = 50/175 (28%), Positives = 58/175 (33%), Gaps = 50/175 (28%)

Query: 37  PSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRR 96
           P G+ G P P G P G +G D   G        P+    P     P  P  P LP +   
Sbjct: 773 PKGDRGFPGPPG-PPGRTGLDGLPG--------PKGDVGPNGQPGPMGP--PGLPGI--- 818

Query: 97  PRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQP 156
                  G  G  GP       G P  G +G+P  +  P  K  P   PP   VP     
Sbjct: 819 -------GVQGPPGP------PGIP--GPIGQPGLHGIPGEKGDP--GPPGLDVP----- 856

Query: 157 APSALFPPPAQLYPAAPTPPALFSPPAGAAFP-------FPVYNGPMA--GVPGP 202
                 PP  +  P  P  P    PP     P       FP   G M   G PGP
Sbjct: 857 -----GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGP 906



 Score = 32.0 bits (71), Expect = 0.65
 Identities = 39/149 (26%), Positives = 48/149 (32%), Gaps = 16/149 (10%)

Query: 39  GEPGPPFPAGMPG--GGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQL--- 93
           G  GPP P G+PG  G  GS        + P    +P  P  P    +P    +P     
Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMS----SLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGP 196

Query: 94  PRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVV 153
           P  P  +   G  G  GP            G  GE     PP P     +      + V 
Sbjct: 197 PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQ--ISEQKRPIDVE 254

Query: 154 LQPAPSALFPPPAQLYPAAPTPPALFSPP 182
            Q     L   P    P  P PP +  PP
Sbjct: 255 FQKGDQGL---PGDRGP--PGPPGIRGPP 278



 Score = 30.0 bits (66), Expect = 2.5
 Identities = 23/66 (34%), Positives = 26/66 (39%), Gaps = 5/66 (7%)

Query: 25   PSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDP--RSPAKPAAPEDP 82
            P    PQ L   P+G PG P   G+PG       K  G P  P  P  R    P  P+  
Sbjct: 1396 PGPQGPQGLPG-PTGPPGDPGRNGLPGFDGAGGRK--GDPGLPGQPGTRGLDGPPGPDGL 1452

Query: 83   QMPAQP 88
            Q P  P
Sbjct: 1453 QGPPGP 1458



 Score = 28.9 bits (63), Expect = 5.5
 Identities = 35/140 (25%), Positives = 42/140 (30%), Gaps = 36/140 (25%)

Query: 101 DEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKA-----------------APLL 143
           D  G  GE G   +   G   H G  G P P  PP P+                   P  
Sbjct: 39  DCSGIKGEKG--ERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPG 96

Query: 144 YPPFPQVPVV-----------LQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVY 192
            P FP  P +            Q  P        + +P +P  P L  PP     P    
Sbjct: 97  LPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIP---- 152

Query: 193 NGPMAGVPGPATVEHRPLPK 212
              M G PG   +   P PK
Sbjct: 153 --GMKGEPGSIIMSSLPGPK 170



 Score = 28.5 bits (62), Expect = 7.2
 Identities = 24/85 (28%), Positives = 28/85 (32%), Gaps = 12/85 (14%)

Query: 37  PSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRR 96
           P G PG P P G+ G    +   G   P  P     P           P  P LP  P+ 
Sbjct: 169 PKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGP-----------PGPPGLPG-PKG 216

Query: 97  PRTLDEDGAAGEAGPVSKAAAGGAP 121
              L+  G  GE G        G P
Sbjct: 217 NMGLNFQGPKGEKGEQGLQGPPGPP 241


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
           sapiens]
          Length = 1685

 Score = 65.1 bits (157), Expect = 7e-11
 Identities = 63/208 (30%), Positives = 73/208 (35%), Gaps = 29/208 (13%)

Query: 21  PAAPPSRTPPQTLKHLP----SGEPGPPFPAGMPG--GGSGSDTKGGGSPATPEDPRSPA 74
           P  PP   PP  +        +G PG P   G+PG  G  G      G P  P +P    
Sbjct: 619 PMGPPGFGPPGPVGEKGIQGVAGNPGQP---GIPGPKGDPGQTITQPGKPGLPGNPGRDG 675

Query: 75  KPAAPEDPQMPAQPALPQLP--RRPRTLDEDGAAGEAGPVSKAAAGGAP-------HIGF 125
               P DP +P QP LP +P  +    +   G  G  GP       G P        IG 
Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735

Query: 126 VGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPP------ALF 179
            G P P   P PK  P    P P  P  L     AL P   + +P  P PP       L 
Sbjct: 736 EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP 795

Query: 180 SP-----PAGAAFPFPVYNGPMAGVPGP 202
            P     P G   P      P  GV GP
Sbjct: 796 GPKGDVGPNGQPGPMGPPGLPGIGVQGP 823



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 57/189 (30%), Positives = 66/189 (34%), Gaps = 22/189 (11%)

Query: 37   PSGEPGPPFPAGMPG-GGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMP---------A 86
            P GEPG P   G PG  GS  D    G P  P  P +  +P  P  P  P          
Sbjct: 1081 PKGEPGLPGYPGNPGIKGSVGDP---GLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISG 1137

Query: 87   QPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHI----GFVGEP--PPYAPPDPKAA 140
             P  P LP  P  +   G  G+ GP  +    G   I    G  GEP  P +  P P   
Sbjct: 1138 PPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGL 1197

Query: 141  PLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVP 200
            P L        +   P    L  P  +  P     P +  PP     P P   GP  G P
Sbjct: 1198 PGLSGQKGDGGLPGIPGNPGLPGPKGE--PGFHGFPGVQGPPGPPGSPGPALEGP-KGNP 1254

Query: 201  GPATVEHRP 209
            GP     RP
Sbjct: 1255 GPQGPPGRP 1263



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 60/201 (29%), Positives = 67/201 (33%), Gaps = 34/201 (16%)

Query: 37   PSGEPGPPFPAGMPG-----GGSGSDTKG-------GGSPATPEDPRSPAKPAAPEDPQM 84
            PSG PG P   G+PG     G  G  + G        G P  P  P +P    +  DP +
Sbjct: 1046 PSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGL 1105

Query: 85   PAQPAL------PQLPRRPRTLDEDGAAGEAGPVSKAAAGGAP-HIGFVGEPPPYAPPDP 137
            P  P        P LP  P T    G  G +GP       G P  +G  G P    PP  
Sbjct: 1106 PGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGE 1165

Query: 138  KA--------APLLYPPFPQVPVVLQPAPSALFPPPAQL----YPAAPTPPALFSPPAGA 185
            K          P      P  P    P P  L     Q      P  P  P L  P    
Sbjct: 1166 KGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEP 1225

Query: 186  AF-PFPVYNGPMA--GVPGPA 203
             F  FP   GP    G PGPA
Sbjct: 1226 GFHGFPGVQGPPGPPGSPGPA 1246



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 59/214 (27%), Positives = 69/214 (32%), Gaps = 33/214 (15%)

Query: 19   PLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPG-----------GGSGSDTKG-GGSPAT 66
            P P  PP    P      P G PG P P G PG           G  G D  G  G   +
Sbjct: 807  PGPMGPPGL--PGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGS 864

Query: 67   PEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHI--- 123
            P  P +P     P  P +P +      P     +   G  G  GP+      G P +   
Sbjct: 865  PGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924

Query: 124  ----GFVGEPPPYAPPDPKAAP-LLYPPFPQVPVVL-------QPA----PSALFPPPAQ 167
                G  G P P      K  P L  PP P  P +L       +P     P    P   Q
Sbjct: 925  DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQ 984

Query: 168  LYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVPG 201
              P  P  P L   P     P P  N  + G PG
Sbjct: 985  GLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPG 1018



 Score = 52.0 bits (123), Expect = 6e-07
 Identities = 50/178 (28%), Positives = 58/178 (32%), Gaps = 20/178 (11%)

Query: 39  GEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPR 98
           G PG P P G PG        G   P  P+  R P     P  P  P  P LP +P    
Sbjct: 60  GLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGP-----PGLPGFPGTPGLPGMP---- 110

Query: 99  TLDEDGAAGEAG-PVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPA 157
               DGA G  G P      G     G  G P    PP P   P +      + +   P 
Sbjct: 111 --GHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPG 168

Query: 158 PSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVPGPATVEHRPLPKDYM 215
           P           P  P PP +   P     P P+      G+ GP      P PK  M
Sbjct: 169 PKG--------NPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNM 218



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 57/185 (30%), Positives = 69/185 (37%), Gaps = 27/185 (14%)

Query: 18  WPLPAAPPSRTPPQTLKHL-----PSGEPGPPFPAGMPG-GGSGSDTKGG-----GSPAT 66
           +P P  PP RT    L        P+G+PGP  P G+PG G  G     G     G P  
Sbjct: 779 FPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGL 838

Query: 67  PEDPRSPAKPAAP--EDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIG 124
              P     P  P  + P  P +   P +P  P  +   G+ G  G   KA A G P  G
Sbjct: 839 HGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPG---KAGASGFP--G 893

Query: 125 FVGEPPPYAPPDPKAAPLLYPPFPQVPVV-----LQPAPSALFP---PPAQLYPAAPTPP 176
             GE     PP P   PL  P    VP +     LQ  P    P     ++  P  P PP
Sbjct: 894 TKGEMGMMGPPGP-PGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPP 952

Query: 177 ALFSP 181
               P
Sbjct: 953 GPMDP 957



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 62/227 (27%), Positives = 74/227 (32%), Gaps = 60/227 (26%)

Query: 39   GEPGPPFP--------------AGMPGGGSGSDTKG-------GGSPATPEDPRSPAKPA 77
            G PGPP P               G+PG    S  KG        G P     P  P  P 
Sbjct: 947  GLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPG 1006

Query: 78   APEDPQMPAQPALPQLPRRPRTLDEDGAAGEAG-------------PVSKAAAG-----G 119
               +P +P QP L   P    T+ + G  G  G             P S    G     G
Sbjct: 1007 PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG 1066

Query: 120  APHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVV-----------LQPAPSALFPPPAQL 168
             P I  +G P     P PK  P L P +P  P +           L   P A   P    
Sbjct: 1067 DPGISSIGLP---GLPGPKGEPGL-PGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPG 1122

Query: 169  YPAAPTPP---ALFSPPAGAAF---PFPVYNGPMAGVPGPATVEHRP 209
            +P  P PP    +  PP        P PV  G   G PGP   + +P
Sbjct: 1123 FPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKP 1169



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 55/199 (27%), Positives = 65/199 (32%), Gaps = 42/199 (21%)

Query: 39  GEPGPPFPAGMPG--GGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRR 96
           G PGPP   G PG  GG   +    G P     P    +   P  P +P  P  P  P R
Sbjct: 267 GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326

Query: 97  PRTLDEDGAAGEAGP----VSKAAAG---------GAPHI-------GFVGEPPPYAPPD 136
                + G  G  GP    + +   G         G P +       GF G   P   P 
Sbjct: 327 DGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPG 386

Query: 137 PKAAPLLYPPFPQ-------------VPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPA 183
           P  A ++ PP P               P +  P P  L   P    P  P PP     PA
Sbjct: 387 PPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGA--PGLPGPPG----PA 440

Query: 184 GAAFPFPVYNGPMAGVPGP 202
           G   P P       G PGP
Sbjct: 441 GPHIP-PSDEICEPGPPGP 458



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 41/135 (30%), Positives = 46/135 (34%), Gaps = 28/135 (20%)

Query: 19   PLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGG-GSPATPE--------- 68
            P P  PP R           G PGP  P G+PG G     KG  G P  P          
Sbjct: 1254 PGPQGPPGRP----------GLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQG 1303

Query: 69   DPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGE 128
             P     P  P    M   P LP +P  P      G  G AGP       G P  G +G 
Sbjct: 1304 PPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGP------EGEP--GLIGP 1355

Query: 129  PPPYAPPDPKAAPLL 143
            P P   P P    ++
Sbjct: 1356 PGPPGLPGPSGQSII 1370



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 52/199 (26%), Positives = 63/199 (31%), Gaps = 42/199 (21%)

Query: 39  GEPGPPFPAGM----PGGGSGSDTKGG-GSPATPEDPRSPAKPAAPEDPQMPAQPALPQL 93
           G+ GPP P G+    PG G     KG  G P  P +      P     P +P  P    +
Sbjct: 334 GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM 393

Query: 94  --PRRPRTLDEDGAAGEAGPVSKAAAG--------GAPHIGFVGEPPPYAPPDPKAAPLL 143
             P  P    E G  G+ GP   +  G        GAP  G  G P P  P  P +  + 
Sbjct: 394 GPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAP--GLPGPPGPAGPHIPPSDEIC 451

Query: 144 YPPFPQVP--------------------VVLQPAPSALFPPPAQLYPAAPTPPALFSPPA 183
            P  P  P                           + +  PP Q     P  P L  PP 
Sbjct: 452 EPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ-----PGLPGLPGPPG 506

Query: 184 GAAFPFPVYNGPMAGVPGP 202
              FP        AG  GP
Sbjct: 507 SLGFPGQKGEKGQAGATGP 525



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 62/200 (31%), Positives = 68/200 (34%), Gaps = 31/200 (15%)

Query: 21  PAAPPSRTPPQTL-KHLPSG----EPGPPFPAGMPG--GGSGSDTKGGGSPATPEDPRSP 73
           P AP    PP     H+P      EPGPP P G PG  G  G      G      D    
Sbjct: 428 PGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQ----GVKGDKGDTCFN 483

Query: 74  AKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYA 133
                   P  P QP LP LP  P +L   G  GE G        G P  G  G P    
Sbjct: 484 CIGTGISGP--PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP--GIPGAPGAPG 539

Query: 134 PPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAP-TP-----PALFSP---PAG 184
            P  K  P     FP     ++     L  P A   P  P TP     P L  P   P G
Sbjct: 540 FPGSKGEPGDILTFPG----MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGG 595

Query: 185 AAFP---FPVYNGPMAGVPG 201
             F     P  N  + G+PG
Sbjct: 596 ITFKGERGPPGNPGLPGLPG 615



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 52/196 (26%), Positives = 60/196 (30%), Gaps = 13/196 (6%)

Query: 25   PSRTPPQTLKHLPS--GEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDP 82
            P +  P   K  P   G PGP    G PG     +    G P           P  P +P
Sbjct: 1157 PGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNP 1216

Query: 83   QMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAP- 141
             +P     P     P      G  G  GP  +   G     G  G P    P  P   P 
Sbjct: 1217 GLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPG 1276

Query: 142  -------LLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFP-FPVYN 193
                      P  P +P  L        PP  Q  P  P    +   P     P FP   
Sbjct: 1277 NGGIKGEKGNPGQPGLP-GLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMK 1335

Query: 194  GPMAGVPGPATVEHRP 209
            GP +GVPG A  E  P
Sbjct: 1336 GP-SGVPGSAGPEGEP 1350



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 39/110 (35%), Positives = 42/110 (38%), Gaps = 12/110 (10%)

Query: 37   PSGEPG---PPFPAGMPG-GGSGSDTKG-GGSPATPEDPRSPAKPAAPEDPQ-MPAQPAL 90
            P GEPG   PP P G+PG  G     KG  G P  P  P     P  P+ PQ +P     
Sbjct: 1346 PEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLP-GPQGPQGLPGPTGP 1404

Query: 91   PQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPP---YAPPDP 137
            P  P R      DGA G  G        G    G  G P P     PP P
Sbjct: 1405 PGDPGRNGLPGFDGAGGRKGDPGLPGQPGTR--GLDGPPGPDGLQGPPGP 1452



 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 54/195 (27%), Positives = 63/195 (32%), Gaps = 22/195 (11%)

Query: 21  PAAPPSRTPPQTLKHLPS-----GEPGPPFPAGMPG--GGSGSDTKGGGSPATPEDPRSP 73
           P  P S+  P  +   P      GE G P   G+PG  G  G D    G P  P     P
Sbjct: 538 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQD----GLPGLPGPKGEP 593

Query: 74  AKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPV-SKAAAGGAPHIGFVGEPPPY 132
                  +   P  P LP LP     +   G  G  GPV  K   G A + G  G P P 
Sbjct: 594 GGITFKGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGPVGEKGIQGVAGNPGQPGIPGPK 652

Query: 133 APPDPKAAPLLYPPFPQVP-----VVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAF 187
             P         P  P  P     V L   P     P     P +   P +     G   
Sbjct: 653 GDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGI----PGIGL 708

Query: 188 PFPVYNGPMAGVPGP 202
           P P       G+PGP
Sbjct: 709 PGPPGPKGFPGIPGP 723



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 36/119 (30%), Positives = 44/119 (36%), Gaps = 11/119 (9%)

Query: 37  PSGEPGPPFPAGMPG--GGSGSDTKGG--GSPATPEDPRSPAKPAAPEDPQMPAQPALPQ 92
           P G PG P   G+PG  G  G+    G  G   T  +   P  P  P     P  P +P 
Sbjct: 94  PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPG 153

Query: 93  LPRRPRTL---DEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYPPFP 148
           +   P ++      G  G  G        G P  G  G P P  PP P    L+ PP P
Sbjct: 154 MKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLP--GPTGIPGPIGPPGPPG--LMGPPGP 208



 Score = 37.0 bits (84), Expect = 0.020
 Identities = 50/175 (28%), Positives = 58/175 (33%), Gaps = 50/175 (28%)

Query: 37  PSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRR 96
           P G+ G P P G P G +G D   G        P+    P     P  P  P LP +   
Sbjct: 773 PKGDRGFPGPPG-PPGRTGLDGLPG--------PKGDVGPNGQPGPMGP--PGLPGI--- 818

Query: 97  PRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQP 156
                  G  G  GP       G P  G +G+P  +  P  K  P   PP   VP     
Sbjct: 819 -------GVQGPPGP------PGIP--GPIGQPGLHGIPGEKGDP--GPPGLDVP----- 856

Query: 157 APSALFPPPAQLYPAAPTPPALFSPPAGAAFP-------FPVYNGPMA--GVPGP 202
                 PP  +  P  P  P    PP     P       FP   G M   G PGP
Sbjct: 857 -----GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGP 906



 Score = 32.0 bits (71), Expect = 0.65
 Identities = 39/149 (26%), Positives = 48/149 (32%), Gaps = 16/149 (10%)

Query: 39  GEPGPPFPAGMPG--GGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQL--- 93
           G  GPP P G+PG  G  GS        + P    +P  P  P    +P    +P     
Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMS----SLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGP 196

Query: 94  PRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVV 153
           P  P  +   G  G  GP            G  GE     PP P     +      + V 
Sbjct: 197 PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQ--ISEQKRPIDVE 254

Query: 154 LQPAPSALFPPPAQLYPAAPTPPALFSPP 182
            Q     L   P    P  P PP +  PP
Sbjct: 255 FQKGDQGL---PGDRGP--PGPPGIRGPP 278



 Score = 30.0 bits (66), Expect = 2.5
 Identities = 23/66 (34%), Positives = 26/66 (39%), Gaps = 5/66 (7%)

Query: 25   PSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDP--RSPAKPAAPEDP 82
            P    PQ L   P+G PG P   G+PG       K  G P  P  P  R    P  P+  
Sbjct: 1390 PGPQGPQGLPG-PTGPPGDPGRNGLPGFDGAGGRK--GDPGLPGQPGTRGLDGPPGPDGL 1446

Query: 83   QMPAQP 88
            Q P  P
Sbjct: 1447 QGPPGP 1452



 Score = 28.9 bits (63), Expect = 5.5
 Identities = 35/140 (25%), Positives = 42/140 (30%), Gaps = 36/140 (25%)

Query: 101 DEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKA-----------------APLL 143
           D  G  GE G   +   G   H G  G P P  PP P+                   P  
Sbjct: 39  DCSGIKGEKG--ERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPG 96

Query: 144 YPPFPQVPVV-----------LQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVY 192
            P FP  P +            Q  P        + +P +P  P L  PP     P    
Sbjct: 97  LPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIP---- 152

Query: 193 NGPMAGVPGPATVEHRPLPK 212
              M G PG   +   P PK
Sbjct: 153 --GMKGEPGSIIMSSLPGPK 170



 Score = 28.5 bits (62), Expect = 7.2
 Identities = 24/85 (28%), Positives = 28/85 (32%), Gaps = 12/85 (14%)

Query: 37  PSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRR 96
           P G PG P P G+ G    +   G   P  P     P           P  P LP  P+ 
Sbjct: 169 PKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGP-----------PGPPGLPG-PKG 216

Query: 97  PRTLDEDGAAGEAGPVSKAAAGGAP 121
              L+  G  GE G        G P
Sbjct: 217 NMGLNFQGPKGEKGEQGLQGPPGPP 241


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
           sapiens]
          Length = 1688

 Score = 65.1 bits (157), Expect = 7e-11
 Identities = 63/208 (30%), Positives = 73/208 (35%), Gaps = 29/208 (13%)

Query: 21  PAAPPSRTPPQTLKHLP----SGEPGPPFPAGMPG--GGSGSDTKGGGSPATPEDPRSPA 74
           P  PP   PP  +        +G PG P   G+PG  G  G      G P  P +P    
Sbjct: 619 PMGPPGFGPPGPVGEKGIQGVAGNPGQP---GIPGPKGDPGQTITQPGKPGLPGNPGRDG 675

Query: 75  KPAAPEDPQMPAQPALPQLP--RRPRTLDEDGAAGEAGPVSKAAAGGAP-------HIGF 125
               P DP +P QP LP +P  +    +   G  G  GP       G P        IG 
Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735

Query: 126 VGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPP------ALF 179
            G P P   P PK  P    P P  P  L     AL P   + +P  P PP       L 
Sbjct: 736 EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLP 795

Query: 180 SP-----PAGAAFPFPVYNGPMAGVPGP 202
            P     P G   P      P  GV GP
Sbjct: 796 GPKGDVGPNGQPGPMGPPGLPGIGVQGP 823



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 57/189 (30%), Positives = 66/189 (34%), Gaps = 22/189 (11%)

Query: 37   PSGEPGPPFPAGMPG-GGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMP---------A 86
            P GEPG P   G PG  GS  D    G P  P  P +  +P  P  P  P          
Sbjct: 1081 PKGEPGLPGYPGNPGIKGSVGDP---GLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISG 1137

Query: 87   QPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHI----GFVGEP--PPYAPPDPKAA 140
             P  P LP  P  +   G  G+ GP  +    G   I    G  GEP  P +  P P   
Sbjct: 1138 PPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGL 1197

Query: 141  PLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVP 200
            P L        +   P    L  P  +  P     P +  PP     P P   GP  G P
Sbjct: 1198 PGLSGQKGDGGLPGIPGNPGLPGPKGE--PGFHGFPGVQGPPGPPGSPGPALEGP-KGNP 1254

Query: 201  GPATVEHRP 209
            GP     RP
Sbjct: 1255 GPQGPPGRP 1263



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 60/201 (29%), Positives = 67/201 (33%), Gaps = 34/201 (16%)

Query: 37   PSGEPGPPFPAGMPG-----GGSGSDTKG-------GGSPATPEDPRSPAKPAAPEDPQM 84
            PSG PG P   G+PG     G  G  + G        G P  P  P +P    +  DP +
Sbjct: 1046 PSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGL 1105

Query: 85   PAQPAL------PQLPRRPRTLDEDGAAGEAGPVSKAAAGGAP-HIGFVGEPPPYAPPDP 137
            P  P        P LP  P T    G  G +GP       G P  +G  G P    PP  
Sbjct: 1106 PGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGE 1165

Query: 138  KA--------APLLYPPFPQVPVVLQPAPSALFPPPAQL----YPAAPTPPALFSPPAGA 185
            K          P      P  P    P P  L     Q      P  P  P L  P    
Sbjct: 1166 KGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEP 1225

Query: 186  AF-PFPVYNGPMA--GVPGPA 203
             F  FP   GP    G PGPA
Sbjct: 1226 GFHGFPGVQGPPGPPGSPGPA 1246



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 59/214 (27%), Positives = 69/214 (32%), Gaps = 33/214 (15%)

Query: 19   PLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPG-----------GGSGSDTKG-GGSPAT 66
            P P  PP    P      P G PG P P G PG           G  G D  G  G   +
Sbjct: 807  PGPMGPPGL--PGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGS 864

Query: 67   PEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHI--- 123
            P  P +P     P  P +P +      P     +   G  G  GP+      G P +   
Sbjct: 865  PGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924

Query: 124  ----GFVGEPPPYAPPDPKAAP-LLYPPFPQVPVVL-------QPA----PSALFPPPAQ 167
                G  G P P      K  P L  PP P  P +L       +P     P    P   Q
Sbjct: 925  DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQ 984

Query: 168  LYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVPG 201
              P  P  P L   P     P P  N  + G PG
Sbjct: 985  GLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPG 1018



 Score = 52.0 bits (123), Expect = 6e-07
 Identities = 50/178 (28%), Positives = 58/178 (32%), Gaps = 20/178 (11%)

Query: 39  GEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPR 98
           G PG P P G PG        G   P  P+  R P     P  P  P  P LP +P    
Sbjct: 60  GLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGP-----PGLPGFPGTPGLPGMP---- 110

Query: 99  TLDEDGAAGEAG-PVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPA 157
               DGA G  G P      G     G  G P    PP P   P +      + +   P 
Sbjct: 111 --GHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPG 168

Query: 158 PSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVPGPATVEHRPLPKDYM 215
           P           P  P PP +   P     P P+      G+ GP      P PK  M
Sbjct: 169 PKG--------NPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNM 218



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 42/135 (31%), Positives = 47/135 (34%), Gaps = 25/135 (18%)

Query: 19   PLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGG-GSPATPE--------- 68
            P P  PP R   Q       G PGP  P G+PG G     KG  G P  P          
Sbjct: 1254 PGPQGPPGRPGFQ-------GLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQG 1306

Query: 69   DPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGE 128
             P     P  P    M   P LP +P  P      G  G AGP       G P  G +G 
Sbjct: 1307 PPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGP------EGEP--GLIGP 1358

Query: 129  PPPYAPPDPKAAPLL 143
            P P   P P    ++
Sbjct: 1359 PGPPGLPGPSGQSII 1373



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 57/185 (30%), Positives = 69/185 (37%), Gaps = 27/185 (14%)

Query: 18  WPLPAAPPSRTPPQTLKHL-----PSGEPGPPFPAGMPG-GGSGSDTKGG-----GSPAT 66
           +P P  PP RT    L        P+G+PGP  P G+PG G  G     G     G P  
Sbjct: 779 FPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGL 838

Query: 67  PEDPRSPAKPAAP--EDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIG 124
              P     P  P  + P  P +   P +P  P  +   G+ G  G   KA A G P  G
Sbjct: 839 HGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPG---KAGASGFP--G 893

Query: 125 FVGEPPPYAPPDPKAAPLLYPPFPQVPVV-----LQPAPSALFP---PPAQLYPAAPTPP 176
             GE     PP P   PL  P    VP +     LQ  P    P     ++  P  P PP
Sbjct: 894 TKGEMGMMGPPGP-PGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPP 952

Query: 177 ALFSP 181
               P
Sbjct: 953 GPMDP 957



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 62/227 (27%), Positives = 74/227 (32%), Gaps = 60/227 (26%)

Query: 39   GEPGPPFP--------------AGMPGGGSGSDTKG-------GGSPATPEDPRSPAKPA 77
            G PGPP P               G+PG    S  KG        G P     P  P  P 
Sbjct: 947  GLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPG 1006

Query: 78   APEDPQMPAQPALPQLPRRPRTLDEDGAAGEAG-------------PVSKAAAG-----G 119
               +P +P QP L   P    T+ + G  G  G             P S    G     G
Sbjct: 1007 PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG 1066

Query: 120  APHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVV-----------LQPAPSALFPPPAQL 168
             P I  +G P     P PK  P L P +P  P +           L   P A   P    
Sbjct: 1067 DPGISSIGLP---GLPGPKGEPGL-PGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPG 1122

Query: 169  YPAAPTPP---ALFSPPAGAAF---PFPVYNGPMAGVPGPATVEHRP 209
            +P  P PP    +  PP        P PV  G   G PGP   + +P
Sbjct: 1123 FPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKP 1169



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 55/199 (27%), Positives = 65/199 (32%), Gaps = 42/199 (21%)

Query: 39  GEPGPPFPAGMPG--GGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRR 96
           G PGPP   G PG  GG   +    G P     P    +   P  P +P  P  P  P R
Sbjct: 267 GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326

Query: 97  PRTLDEDGAAGEAGP----VSKAAAG---------GAPHI-------GFVGEPPPYAPPD 136
                + G  G  GP    + +   G         G P +       GF G   P   P 
Sbjct: 327 DGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPG 386

Query: 137 PKAAPLLYPPFPQ-------------VPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPA 183
           P  A ++ PP P               P +  P P  L   P    P  P PP     PA
Sbjct: 387 PPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGA--PGLPGPPG----PA 440

Query: 184 GAAFPFPVYNGPMAGVPGP 202
           G   P P       G PGP
Sbjct: 441 GPHIP-PSDEICEPGPPGP 458



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 52/199 (26%), Positives = 63/199 (31%), Gaps = 42/199 (21%)

Query: 39  GEPGPPFPAGM----PGGGSGSDTKGG-GSPATPEDPRSPAKPAAPEDPQMPAQPALPQL 93
           G+ GPP P G+    PG G     KG  G P  P +      P     P +P  P    +
Sbjct: 334 GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVM 393

Query: 94  --PRRPRTLDEDGAAGEAGPVSKAAAG--------GAPHIGFVGEPPPYAPPDPKAAPLL 143
             P  P    E G  G+ GP   +  G        GAP  G  G P P  P  P +  + 
Sbjct: 394 GPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAP--GLPGPPGPAGPHIPPSDEIC 451

Query: 144 YPPFPQVP--------------------VVLQPAPSALFPPPAQLYPAAPTPPALFSPPA 183
            P  P  P                           + +  PP Q     P  P L  PP 
Sbjct: 452 EPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ-----PGLPGLPGPPG 506

Query: 184 GAAFPFPVYNGPMAGVPGP 202
              FP        AG  GP
Sbjct: 507 SLGFPGQKGEKGQAGATGP 525



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 62/200 (31%), Positives = 68/200 (34%), Gaps = 31/200 (15%)

Query: 21  PAAPPSRTPPQTL-KHLPSG----EPGPPFPAGMPG--GGSGSDTKGGGSPATPEDPRSP 73
           P AP    PP     H+P      EPGPP P G PG  G  G      G      D    
Sbjct: 428 PGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQ----GVKGDKGDTCFN 483

Query: 74  AKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYA 133
                   P  P QP LP LP  P +L   G  GE G        G P  G  G P    
Sbjct: 484 CIGTGISGP--PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP--GIPGAPGAPG 539

Query: 134 PPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAP-TP-----PALFSP---PAG 184
            P  K  P     FP     ++     L  P A   P  P TP     P L  P   P G
Sbjct: 540 FPGSKGEPGDILTFPG----MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGG 595

Query: 185 AAFP---FPVYNGPMAGVPG 201
             F     P  N  + G+PG
Sbjct: 596 ITFKGERGPPGNPGLPGLPG 615



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 53/199 (26%), Positives = 62/199 (31%), Gaps = 16/199 (8%)

Query: 25   PSRTPPQTLKHLPS--GEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDP 82
            P +  P   K  P   G PGP    G PG     +    G P           P  P +P
Sbjct: 1157 PGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNP 1216

Query: 83   QMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPL 142
             +P     P     P      G  G  GP  +   G     G  G P     P P+  P 
Sbjct: 1217 GLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPG 1276

Query: 143  L-----------YPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFP-FP 190
            L            P  P +P  L        PP  Q  P  P    +   P     P FP
Sbjct: 1277 LPGNGGIKGEKGNPGQPGLP-GLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFP 1335

Query: 191  VYNGPMAGVPGPATVEHRP 209
               GP +GVPG A  E  P
Sbjct: 1336 GMKGP-SGVPGSAGPEGEP 1353



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 39/110 (35%), Positives = 42/110 (38%), Gaps = 12/110 (10%)

Query: 37   PSGEPG---PPFPAGMPG-GGSGSDTKG-GGSPATPEDPRSPAKPAAPEDPQ-MPAQPAL 90
            P GEPG   PP P G+PG  G     KG  G P  P  P     P  P+ PQ +P     
Sbjct: 1349 PEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLP-GPQGPQGLPGPTGP 1407

Query: 91   PQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPP---YAPPDP 137
            P  P R      DGA G  G        G    G  G P P     PP P
Sbjct: 1408 PGDPGRNGLPGFDGAGGRKGDPGLPGQPGTR--GLDGPPGPDGLQGPPGP 1455



 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 54/195 (27%), Positives = 63/195 (32%), Gaps = 22/195 (11%)

Query: 21  PAAPPSRTPPQTLKHLPS-----GEPGPPFPAGMPG--GGSGSDTKGGGSPATPEDPRSP 73
           P  P S+  P  +   P      GE G P   G+PG  G  G D    G P  P     P
Sbjct: 538 PGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQD----GLPGLPGPKGEP 593

Query: 74  AKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPV-SKAAAGGAPHIGFVGEPPPY 132
                  +   P  P LP LP     +   G  G  GPV  K   G A + G  G P P 
Sbjct: 594 GGITFKGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGPVGEKGIQGVAGNPGQPGIPGPK 652

Query: 133 APPDPKAAPLLYPPFPQVP-----VVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAF 187
             P         P  P  P     V L   P     P     P +   P +     G   
Sbjct: 653 GDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGI----PGIGL 708

Query: 188 PFPVYNGPMAGVPGP 202
           P P       G+PGP
Sbjct: 709 PGPPGPKGFPGIPGP 723



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 36/119 (30%), Positives = 44/119 (36%), Gaps = 11/119 (9%)

Query: 37  PSGEPGPPFPAGMPG--GGSGSDTKGG--GSPATPEDPRSPAKPAAPEDPQMPAQPALPQ 92
           P G PG P   G+PG  G  G+    G  G   T  +   P  P  P     P  P +P 
Sbjct: 94  PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPG 153

Query: 93  LPRRPRTL---DEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYPPFP 148
           +   P ++      G  G  G        G P  G  G P P  PP P    L+ PP P
Sbjct: 154 MKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLP--GPTGIPGPIGPPGPPG--LMGPPGP 208



 Score = 37.0 bits (84), Expect = 0.020
 Identities = 50/175 (28%), Positives = 58/175 (33%), Gaps = 50/175 (28%)

Query: 37  PSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRR 96
           P G+ G P P G P G +G D   G        P+    P     P  P  P LP +   
Sbjct: 773 PKGDRGFPGPPG-PPGRTGLDGLPG--------PKGDVGPNGQPGPMGP--PGLPGI--- 818

Query: 97  PRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQP 156
                  G  G  GP       G P  G +G+P  +  P  K  P   PP   VP     
Sbjct: 819 -------GVQGPPGP------PGIP--GPIGQPGLHGIPGEKGDP--GPPGLDVP----- 856

Query: 157 APSALFPPPAQLYPAAPTPPALFSPPAGAAFP-------FPVYNGPMA--GVPGP 202
                 PP  +  P  P  P    PP     P       FP   G M   G PGP
Sbjct: 857 -----GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGP 906



 Score = 32.0 bits (71), Expect = 0.65
 Identities = 39/149 (26%), Positives = 48/149 (32%), Gaps = 16/149 (10%)

Query: 39  GEPGPPFPAGMPG--GGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQL--- 93
           G  GPP P G+PG  G  GS        + P    +P  P  P    +P    +P     
Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMS----SLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGP 196

Query: 94  PRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVV 153
           P  P  +   G  G  GP            G  GE     PP P     +      + V 
Sbjct: 197 PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQ--ISEQKRPIDVE 254

Query: 154 LQPAPSALFPPPAQLYPAAPTPPALFSPP 182
            Q     L   P    P  P PP +  PP
Sbjct: 255 FQKGDQGL---PGDRGP--PGPPGIRGPP 278



 Score = 30.0 bits (66), Expect = 2.5
 Identities = 23/66 (34%), Positives = 26/66 (39%), Gaps = 5/66 (7%)

Query: 25   PSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDP--RSPAKPAAPEDP 82
            P    PQ L   P+G PG P   G+PG       K  G P  P  P  R    P  P+  
Sbjct: 1393 PGPQGPQGLPG-PTGPPGDPGRNGLPGFDGAGGRK--GDPGLPGQPGTRGLDGPPGPDGL 1449

Query: 83   QMPAQP 88
            Q P  P
Sbjct: 1450 QGPPGP 1455



 Score = 28.9 bits (63), Expect = 5.5
 Identities = 35/140 (25%), Positives = 42/140 (30%), Gaps = 36/140 (25%)

Query: 101 DEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKA-----------------APLL 143
           D  G  GE G   +   G   H G  G P P  PP P+                   P  
Sbjct: 39  DCSGIKGEKG--ERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPG 96

Query: 144 YPPFPQVPVV-----------LQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVY 192
            P FP  P +            Q  P        + +P +P  P L  PP     P    
Sbjct: 97  LPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIP---- 152

Query: 193 NGPMAGVPGPATVEHRPLPK 212
              M G PG   +   P PK
Sbjct: 153 --GMKGEPGSIIMSSLPGPK 170



 Score = 28.5 bits (62), Expect = 7.2
 Identities = 24/85 (28%), Positives = 28/85 (32%), Gaps = 12/85 (14%)

Query: 37  PSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRR 96
           P G PG P P G+ G    +   G   P  P     P           P  P LP  P+ 
Sbjct: 169 PKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGP-----------PGPPGLPG-PKG 216

Query: 97  PRTLDEDGAAGEAGPVSKAAAGGAP 121
              L+  G  GE G        G P
Sbjct: 217 NMGLNFQGPKGEKGEQGLQGPPGPP 241


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 68/204 (33%), Positives = 80/204 (39%), Gaps = 30/204 (14%)

Query: 20  LPAAPPS--RTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPA 77
           LPA PP   R PP  +  LP   P PP P  +P          GG P  P  P  PA   
Sbjct: 223 LPAGPPGVKRPPPPLMNGLP---PRPPLPESLP------PPPPGGLPLPPMPPTGPAPSG 273

Query: 78  APEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGP---VSKAAAGGAPHIGFVGEPP---- 130
            P  PQ+P  P  P +   P  +    A+G   P   V   A G  P    V  P     
Sbjct: 274 PPGPPQLP--PPAPGV-HPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVH 330

Query: 131 PYAPPDPKAAPLLYPPFPQV----PVVLQPAPSALFPPPAQLYPAA----PTPPALFSPP 182
           P AP     AP ++PP P V    P V  PAP    PP A ++P A    P  PA+    
Sbjct: 331 PPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQA 390

Query: 183 AGAAFPFPVYNGPMAGV-PGPATV 205
            G   P P  +    GV P P  V
Sbjct: 391 PGVHPPAPGMHPQAPGVHPQPPGV 414



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 48/149 (32%), Positives = 59/149 (39%), Gaps = 15/149 (10%)

Query: 67  PEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFV 126
           P  P  PA P   + P  P    LP  P  P +L      G   P         P  G  
Sbjct: 218 PAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPM-------PPTGPA 270

Query: 127 GEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPT--PPA--LFSPP 182
              PP  P  P  AP ++PP P    V+ P  S + PP   ++P AP   PPA  +  P 
Sbjct: 271 PSGPPGPPQLPPPAPGVHPPAP----VVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPT 326

Query: 183 AGAAFPFPVYNGPMAGVPGPATVEHRPLP 211
           +G   P P  + P  GV  PA   H P P
Sbjct: 327 SGVHPPAPGVHPPAPGVHPPAPGVHPPAP 355



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 61/203 (30%), Positives = 72/203 (35%), Gaps = 38/203 (18%)

Query: 19  PLPAAPPSRTPPQTLKHLPSGEPG--PPFP-AGMPGGGSGSDTKGGGSPATPEDPRSPAK 75
           P P+ PP   PPQ    LP   PG  PP P    P  G      G   PA    P +P  
Sbjct: 269 PAPSGPPG--PPQ----LPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGV 322

Query: 76  PAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPP----- 130
                    PA    P  P         G    A  V   A G  P    V  PP     
Sbjct: 323 HPPTSGVHPPAPGVHPPAP---------GVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVH 373

Query: 131 PYAPPDPKAAPLLYPPFPQVPVVLQPAPS------ALFPPPAQLYPAA----PTPPALFS 180
           P AP    AAP ++   PQ P V  PAP        + P P  ++P+A    P PP +  
Sbjct: 374 PQAPGVHPAAPAVH---PQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHP 430

Query: 181 PPAGAAFPFPVYNGPMAGVPGPA 203
              G   P P+   PM   P P+
Sbjct: 431 SNPGVHPPTPM--PPMLRPPLPS 451



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 43/153 (28%), Positives = 56/153 (36%), Gaps = 12/153 (7%)

Query: 25  PSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQM 84
           P   PP +  H P+    PP P   P          G  P  P     P+    P+ P +
Sbjct: 320 PGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGV 379

Query: 85  -PAQPAL-PQLPR-RPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAP 141
            PA PA+ PQ P   P        A    P        AP  G   +PP   P +P    
Sbjct: 380 HPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAP--GVHPQPPGVHPSNPG--- 434

Query: 142 LLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPT 174
            ++PP P  P++  P PS     P  + P  PT
Sbjct: 435 -VHPPTPMPPMLRPPLPS---EGPGNIPPPPPT 463


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 60/199 (30%), Positives = 80/199 (40%), Gaps = 32/199 (16%)

Query: 19  PLPAA---PPSRTPPQTLKHLPSGEPGPPFPAGM--PGGGSGSD---TKGGGSPATPEDP 70
           P P+A   PP+  P +++          P PA    P  G G     ++   S ATP   
Sbjct: 192 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 251

Query: 71  RSPAKPAAPEDPQMPAQPALP-----QLPRRPR-TLDEDGAAGEAGPVSKAAAGGAPHIG 124
            + + P+A   P+ PA P+ P     Q  R P+ T     AA   GP+S +        G
Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSG 311

Query: 125 FVGEPPPYAPPDPKAAPL---------------LYPPFPQVPVVLQPAPSALFPPPAQLY 169
               P P  PPD  A PL               L PP P  P  LQ  PS    PP+Q  
Sbjct: 312 TKARPVP--PPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAP 369

Query: 170 PAAPTPPALFSPPAGAAFP 188
           P+  TPP + +PP+    P
Sbjct: 370 PSMTTPP-MQAPPSLQTIP 387



 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 70/220 (31%), Positives = 87/220 (39%), Gaps = 30/220 (13%)

Query: 5   SPICKQLREMLERWPLPAAPPSRTPPQTL-----KHLPSGEPGPPFPAGMPGGGSGSDTK 59
           +P+   +   LE     A P  +TPP +L     ++LPS  P P   A  P      +T 
Sbjct: 502 APLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETP 561

Query: 60  GGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGG 119
              +P   + P SP     PE P   A P     P+ P  L      G   P     A  
Sbjct: 562 PCPAPCPLQAPPSPLTTPPPETPSSIATPP----PQAPPALASPPLQGLPSPPLSPLATP 617

Query: 120 APHI-GFVGEPPPYAPPDPKAAPLLYP---PFPQVPVVL---------QPAPS----ALF 162
            P     +  PP  APP P A+P L P   P PQ P  L          P PS    A F
Sbjct: 618 PPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 677

Query: 163 PPPAQLYPAAP--TPPALFSPPAGAAFPFPVYNGPMAGVP 200
            PPA   P +P  TPP+  +PP+ AA P  V   P A  P
Sbjct: 678 SPPAS-PPVSPSATPPSQ-APPSLAAPPLQVPPSPPASPP 715



 Score = 58.5 bits (140), Expect = 6e-09
 Identities = 69/230 (30%), Positives = 86/230 (37%), Gaps = 53/230 (23%)

Query: 19  PLPAAPPS-RTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPA 77
           P P APP+  TPP  L+ LPS  P   FP   P   S S      +   P+ P   A P 
Sbjct: 784 PPPQAPPALATPP--LQALPS--PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 839

Query: 78  APEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGP-VSKAAAGGAPHIGFVGEPPPYAPPD 136
               P  PA P L Q PRRP T   D +   +GP ++ A A G P       PP  +P  
Sbjct: 840 LQVPPSPPASPTL-QAPRRPPTPGPDTSV--SGPRLTLALAPGPP------PPPSRSPSS 890

Query: 137 PKAAPLL----------------YPPFPQVPVVLQPAPSALFPPPAQLYPAA----PTPP 176
             + P L                Y   P+      P P A     A  +PAA    P PP
Sbjct: 891 TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL---AACHPAAWSRGPAPP 947

Query: 177 ALFSPPAGAAFPFP-------------VY--NGPMAGVPGPATVEHRPLP 211
             F    GA  P+P             +Y   GP +  P P  ++  P P
Sbjct: 948 LAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 997



 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 61/200 (30%), Positives = 70/200 (35%), Gaps = 25/200 (12%)

Query: 15  LERWPLPAAPPSRTPPQTLKHLPSGEPGP---PFPAGMPGGGSGSDTKGGGSPATPEDPR 71
           LE  P PA  P + PP  L   P   P     P P   P   S         P     P 
Sbjct: 558 LETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALAS---------PPLQGLPS 608

Query: 72  SPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPP 131
            P  P A   PQ P   ALP L   P        +  A P  +A    A H+      PP
Sbjct: 609 PPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 668

Query: 132 YAPPDPKAAPLLYPPFPQVPVVLQP---APSALFPPPAQLYPAAPTPPALF--------S 180
             P  P  AP   P  P V     P   AP +L  PP Q+ P+ P  P +         +
Sbjct: 669 --PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 726

Query: 181 PPAGAAFPFPVYNGPMAGVP 200
           PP  AA P  V   P A  P
Sbjct: 727 PPPLAAPPLQVPPSPPASPP 746



 Score = 55.1 bits (131), Expect = 7e-08
 Identities = 55/190 (28%), Positives = 69/190 (36%), Gaps = 20/190 (10%)

Query: 21  PAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPA-KPAAP 79
           P +PP  +PP      P   P P  P+  P   +            P  P SP   P+A 
Sbjct: 664 PFSPPP-SPPVQAPFSPPASP-PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 721

Query: 80  EDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIG-FVGEPPPYAPPDPK 138
             PQ P   A P L   P        +  A P    +A   P +   +  PP   PP P 
Sbjct: 722 PPPQAPPPLAAPPLQVPP--------SPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPP 773

Query: 139 AA----PLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFP----FP 190
           A+    PL  PP    P +  P   AL  PPA     AP  P+   P +  A P     P
Sbjct: 774 ASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 833

Query: 191 VYNGPMAGVP 200
           V   P+  VP
Sbjct: 834 VLAAPLLQVP 843



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 58/210 (27%), Positives = 71/210 (33%), Gaps = 27/210 (12%)

Query: 19  PLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAA 78
           P  AAPP + PP      P      P P   P   +         PA+P  P SP+    
Sbjct: 697 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP--PMSPSATPP 754

Query: 79  PEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGG------APHIGFVGEPP-- 130
           P  P + A P L   P  P +L     A        A A        +P   F G+ P  
Sbjct: 755 PRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 814

Query: 131 --------PYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPP 182
                   P A P P+A P+L  P  QVP    P+P A     A   P  P P    S P
Sbjct: 815 PSASLPMSPLATPPPQAPPVLAAPLLQVP----PSPPASPTLQAPRRPPTPGPDTSVSGP 870

Query: 183 -----AGAAFPFPVYNGPMAGVPGPATVEH 207
                     P P    P + + GP    H
Sbjct: 871 RLTLALAPGPPPPPSRSPSSTLSGPDLAGH 900



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 60/199 (30%), Positives = 72/199 (36%), Gaps = 41/199 (20%)

Query: 21  PAAPPSRTPPQTLK-HLP----SGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAK 75
           P A PS   P  L  HL     S  P PP  A                PA+P     P  
Sbjct: 644 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF------------SPPASP-----PVS 686

Query: 76  PAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAG-GAPHIGFVGEPPPYAP 134
           P+A    Q P   A P L   P        +  A P  +A     AP +    + PP  P
Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL----QVPPSPP 742

Query: 135 PDPKAAPLLYPPFPQVPVVL-------QPAPSALFP------PPAQLYPAAPTPPALFSP 181
             P  +P   PP P+VP +L        P+P A  P      PP Q  PA  TPP    P
Sbjct: 743 ASPPMSPSATPP-PRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALP 801

Query: 182 PAGAAFPFPVYNGPMAGVP 200
              A+FP      P A +P
Sbjct: 802 SPPASFPGQAPFSPSASLP 820



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 50/170 (29%), Positives = 68/170 (40%), Gaps = 26/170 (15%)

Query: 19  PLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSP-ATPEDPRSPAKPA 77
           P   A PS+  P+ L+ L   +  PP     P  G  S      SP ATP    + A+P 
Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS-----SPLATPSPSGTKARPV 317

Query: 78  APEDPQMPAQPA-LPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPD 136
            P D      PA LP  P     L          P++  +    P +  +  PP  A P 
Sbjct: 318 PPPDNAATPLPATLPPSPPLATPL----------PLAPPSPSAPPSLQTLPSPP--ATPP 365

Query: 137 PKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAA 186
            +A P +  P  Q P      PS    PP Q+ P + T P+L +PP+  A
Sbjct: 366 SQAPPSMTTPPMQAP------PSLQTIPPIQV-PHSLTSPSLQAPPSPLA 408



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 63/253 (24%), Positives = 84/253 (33%), Gaps = 76/253 (30%)

Query: 19  PLPAAPPSRTPPQTLKHLPSGEPGPPF---------------------PAGMPGG----- 52
           PLP APPS + P +L+ LPS    PP                      P  +P       
Sbjct: 340 PLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPS 399

Query: 53  ----------GSGSDTKGGGSPA--------------TPEDPRSPAKPAA--PEDPQMPA 86
                      S   T   GSP               T     SP++PA+  P+ P + A
Sbjct: 400 LQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQA 459

Query: 87  QPALPQLPRRPRTLDEDGAAGEAGPVS----KAAAGGAPHIGFVGEPPPYAPPDPKAAPL 142
             +LP  P    +L     +  + P++    +A +  A H        P AP      P 
Sbjct: 460 PLSLPASPPLQTSLSP-AVSPLSSPLTIHPLQALSSLASH-------SPQAPLSSLIMPP 511

Query: 143 LYPPFPQVPVVLQPAPSA-----------LFPPPAQLYPAAPTPPALFSPPAGAAFPFPV 191
           L       P  LQ  P++           L PPP Q   A  T P L +PP  A  P   
Sbjct: 512 LETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQA 571

Query: 192 YNGPMAGVPGPAT 204
              P+   P P T
Sbjct: 572 PPSPLT-TPPPET 583



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 45/170 (26%), Positives = 64/170 (37%), Gaps = 21/170 (12%)

Query: 53  GSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMP--AQPALPQLPRRPRTLDEDGAAGEAG 110
           G+  DT G  +P TP    +    AA  +  +P  A  A P+ P          A+  + 
Sbjct: 159 GARRDTSGP-TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHST 217

Query: 111 PVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYP 170
                AA   P  G   + P        A PL  P         +  PSA   P A  +P
Sbjct: 218 TEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA--------RSGPSARGTPRAPAHP 269

Query: 171 AAPTP-------PALFSPPAGAAFPF--PVYNGPMAGVPGPATVEHRPLP 211
           + P P       P   +PP   A P   P+ + P+A  P P+  + RP+P
Sbjct: 270 SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA-TPSPSGTKARPVP 318



 Score = 36.6 bits (83), Expect = 0.026
 Identities = 52/204 (25%), Positives = 73/204 (35%), Gaps = 37/204 (18%)

Query: 20  LPAAPPSRT----------------PPQTLKHLPSGEPGPPFPAG-MPGGGSGSDTKGGG 62
           LPA+PP +T                P Q L  L S  P  P  +  MP      +T+   
Sbjct: 463 LPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPP----LETQSSL 518

Query: 63  SPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPH 122
           +P + + P     PA+   P +   P+L   P +  +        E  P        AP 
Sbjct: 519 APPSLQTP-----PASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAP- 572

Query: 123 IGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPP--AQL-YPAAPTPPALF 179
                 P P   P P+    +  P PQ P  L   P    P P  + L  P    PP L 
Sbjct: 573 ------PSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLA 626

Query: 180 SPPAGAAFPFPVYNGPMAGVPGPA 203
            PP  A  P P  + P++ +  P+
Sbjct: 627 LPPLQAP-PSPPASPPLSPLATPS 649



 Score = 36.2 bits (82), Expect = 0.034
 Identities = 53/189 (28%), Positives = 66/189 (34%), Gaps = 19/189 (10%)

Query: 5    SPICKQLREMLERWPLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGG-SGSDTKGGGS 63
            SP      +   R P P    S + P+    L  G P P  P+  P    SG D  G  S
Sbjct: 845  SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP--PSRSPSSTLSGPDLAGHSS 902

Query: 64   PATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHI 123
             AT          + PE     + P   +L           AA   GP    A  GAP  
Sbjct: 903  SATSTPEELRGYDSGPEGGAAASPPPDAELAAC------HPAAWSRGPAPPLAFRGAP-- 954

Query: 124  GFVGEPPPYAP-PDPKAAPLLYPPF-PQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSP 181
               G P P+ P   P +A  L   +  + P    PAP AL P P+   P      A    
Sbjct: 955  ---GAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPS---PGTSGGKAAAGA 1008

Query: 182  PAGAAFPFP 190
             AGA+   P
Sbjct: 1009 GAGASSRSP 1017



 Score = 30.4 bits (67), Expect = 1.9
 Identities = 32/109 (29%), Positives = 40/109 (36%), Gaps = 10/109 (9%)

Query: 18   WPLPAAPPSRTPPQTLKHLPSGE-----PGPPFPAGMPGGGSGSDTKGGGSPATPEDPRS 72
            WP    P S     T+      E     PG   P   PG   G    G G+ A+    RS
Sbjct: 960  WPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGAS---SRS 1016

Query: 73   PAKPAAPEDPQMPAQPALPQ--LPRRPRTLDEDGAAGEAGPVSKAAAGG 119
            P +    E P    Q ++ Q  L R       +GAAG +G     A GG
Sbjct: 1017 PKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGG 1065


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 68/222 (30%), Positives = 82/222 (36%), Gaps = 49/222 (22%)

Query: 19  PLPAAPPSRTPPQTLKHLPSGEPGP--------PFPAGMPGGGSGSDTKGGGSPATPEDP 70
           P+PAA      P+     P+   GP        P P   PG G G    G G PA P   
Sbjct: 139 PVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPG---PGPGKPAGPGAA 195

Query: 71  RSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGA-----PHIGF 125
           ++    AA  +    A PA+  +   P  L          P+ K AA G      P +G 
Sbjct: 196 QTLNGSAALLNSHHAAAPAVSLVNNGPAAL---------LPLPKPAAPGTVIQTPPFVGA 246

Query: 126 VGEPPPYAPPDP----KAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSP 181
              P P AP  P     AAP   PP P       PAP+ L  PP   +PA P   A   P
Sbjct: 247 AAPPAPAAPSPPAAPAPAAPAAAPPPP------PPAPATLARPPG--HPAGPPTAAPAVP 298

Query: 182 PAGAA----------FPFPVYNGP--MAGVPGPATVEHRPLP 211
           P  AA           P P   GP  ++G PGP      P P
Sbjct: 299 PPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAP 340



 Score = 61.6 bits (148), Expect = 8e-10
 Identities = 71/223 (31%), Positives = 80/223 (35%), Gaps = 39/223 (17%)

Query: 21  PAAPPSRTPPQTLKHLPSGEPGPPFPAGM--PGGGSGSDTKGGGSPATPEDPRSPAKPAA 78
           PA      P    +  P   P PP PAG   PGGG G    G  SP  P  P  PA PAA
Sbjct: 67  PAGAAGAGPAAPAEGAPGAAPEPP-PAGRARPGGG-GPQRPGPPSPRRPLVPAGPAPPAA 124

Query: 79  PEDP----------QMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGE 128
              P           +PA  A+   P  P        AG A   ++A  G  P  G    
Sbjct: 125 KLRPPPEGSAGSCAPVPAAAAVAAGP-EPAPAGPAKPAGPAALAARAGPGPGPGPGPGPG 183

Query: 129 PPPYAPPDPKAAPLL----------YPPFPQVPVVLQPAPSALFPPPAQLYP-------- 170
           P P  P  P AA  L          +   P V +V    P+AL P P    P        
Sbjct: 184 PGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLV-NNGPAALLPLPKPAAPGTVIQTPP 242

Query: 171 ----AAPTPPALFSPPAGAAFPFPVYNGPMAGVPGPATVEHRP 209
               AAP  PA  SPPA  A P      P    P PAT+   P
Sbjct: 243 FVGAAAPPAPAAPSPPAAPA-PAAPAAAPPPPPPAPATLARPP 284



 Score = 51.6 bits (122), Expect = 8e-07
 Identities = 58/191 (30%), Positives = 72/191 (37%), Gaps = 36/191 (18%)

Query: 19  PLPAAPPS--RTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKP 76
           P PAAP +  +TPP        G   PP PA      + +      +P  P  P +PA  
Sbjct: 229 PKPAAPGTVIQTPPFV------GAAAPPAPAAPSPPAAPAPAAPAAAPPPP--PPAPATL 280

Query: 77  AAPEDPQMPAQP--ALPQLPRRPRTLDEDGAAGEAGPVSKAAAGG--------------- 119
           A P  P  PA P  A P +P  P    ++G +  A P    AAGG               
Sbjct: 281 ARP--PGHPAGPPTAAPAVP--PPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAA 336

Query: 120 APHIGFVGEPPPY----APPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAP-T 174
           AP  G   E P      APP  +      P      +V+ P      P PA + P AP T
Sbjct: 337 APAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGT 396

Query: 175 PPALFSPPAGA 185
           P  L    AGA
Sbjct: 397 PTGLPKGAAGA 407



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 50/180 (27%), Positives = 57/180 (31%), Gaps = 27/180 (15%)

Query: 19  PLPAAPPSRTPPQTLKHLPSGEPGPPF-------PAGMPGGGSG------SDTKGG---- 61
           P  A PP    P TL   P    GPP        PA    GGS       +   GG    
Sbjct: 266 PAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGV 325

Query: 62  -GSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGP--VSKAAAG 118
            G P       +PA     E P+   Q A    P   +TL   G A  A    +     G
Sbjct: 326 SGQPGPGAAAAAPAPGVKAESPKRVVQAA----PPAAQTLAASGPASTAASMVIGPTMQG 381

Query: 119 GAPHIGFVGEPPPYAPPD-PK-AAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPP 176
             P    V  P P  P   PK AA  +     + P        A   P   L P  P PP
Sbjct: 382 ALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTV-LAPRLPQPP 440


>gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo
            sapiens]
          Length = 1751

 Score = 61.6 bits (148), Expect = 8e-10
 Identities = 46/127 (36%), Positives = 52/127 (40%), Gaps = 16/127 (12%)

Query: 37   PSGEPGPPFPAGMPG--------GGSGSDTKG-GGSPATPEDPRSPAKPAAPEDPQMPAQ 87
            P G PGPP P G+PG        G + SD  G  G P  P     P  P  P  P  P +
Sbjct: 901  PRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGR 960

Query: 88   PALPQLPRRPRTLDEDGAAGEAGPVSKAA---AGGAPHIGFVGEPPPYAPPDPKAAPLLY 144
               P    +  +L E GA G  G  SK A   AG     G  G P P  PP P   P   
Sbjct: 961  EGPPGRTGQKGSLGEAGAPGHKG--SKGAPGPAGARGESGLAGAPGPAGPPGPPGPP--G 1016

Query: 145  PPFPQVP 151
            PP P +P
Sbjct: 1017 PPGPGLP 1023



 Score = 58.9 bits (141), Expect = 5e-09
 Identities = 58/195 (29%), Positives = 72/195 (36%), Gaps = 12/195 (6%)

Query: 37   PSGEPGPPFPAGMPGGGSG--SDTKGGGSPATPEDPRSPAKPAAPED---PQMPAQPALP 91
            P G PGPP P G P   S   +++   G P  P +   P    A  +   P  P Q    
Sbjct: 1256 PPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFD 1315

Query: 92   QLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGE--PPPYAPPDPKAAPLLYPPFPQ 149
             L        E G  G+AG   +    G    GF G   P P  PP P+  P +  P  +
Sbjct: 1316 FLQLEAEMKGEKGDRGDAGQKGERGEPGGG--GFFGSSLPGPPGPPGPRGYPGIPGPKGE 1373

Query: 150  VPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVPGPATVEHRP 209
              +  QP P     PP   Y     PP    PP   +FP P  +     VPGP      P
Sbjct: 1374 -SIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGP--HRQTISVPGPPGPPGPP 1430

Query: 210  LPKDYMMESVLVTLF 224
             P   M  S  V L+
Sbjct: 1431 GPPGTMGASSGVRLW 1445



 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 63/227 (27%), Positives = 76/227 (33%), Gaps = 62/227 (27%)

Query: 19   PLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGG----------------G 62
            P PA PP           P G PGPP P G+P G    +  GG                G
Sbjct: 1003 PGPAGPPG----------PPGPPGPPGP-GLPAGFDDMEGSGGPFWSTARSADGPQGPPG 1051

Query: 63   SPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPH 122
             P    DP  P  P A  +      P  P LP R       G  G+ G   +    G   
Sbjct: 1052 LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG 1111

Query: 123  IGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPS-----ALFPPPA----------Q 167
            +G  G P P  PP     P++Y       V+  P P      A FP PA          +
Sbjct: 1112 VGQPGLPGPPGPP----GPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGE 1167

Query: 168  LYPAAP-----TPPALFSPPAGAAFPF-------PVYNGPMAGVPGP 202
                 P      P ++FSP  GA  P        P + GP    PGP
Sbjct: 1168 RGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGP----PGP 1210



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 54/194 (27%), Positives = 62/194 (31%), Gaps = 30/194 (15%)

Query: 39  GEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRR-- 96
           G PGPP  AG PG        G   P +P  P  PA    P     P  P     P R  
Sbjct: 761 GVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDG 820

Query: 97  -PRTLDEDGAAGEAGP---------VSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYPP 146
            P    EDG  G+ GP         V      G P +G  G P P  PP P      +  
Sbjct: 821 EPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDK 880

Query: 147 FPQVPV----------VLQPAPSALFPPPAQLYPAAPTPPALF-----SPPAGAAFP-FP 190
              + +           L+       PP     P  P  P  F       P  A  P  P
Sbjct: 881 LTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVP 940

Query: 191 VYNGP--MAGVPGP 202
              GP    G+PGP
Sbjct: 941 GREGPPGFPGLPGP 954



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 46/176 (26%), Positives = 55/176 (31%), Gaps = 31/176 (17%)

Query: 21   PAAPPSRTPPQTLKHLPSGEPGPPFPAGM----------PGGGSGSDTKGGGSPATPEDP 70
            P  P ++ PP        GE GPP P G              G   D    G      +P
Sbjct: 1285 PGLPGNQGPPGPKG--AKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEP 1342

Query: 71   RSPA--KPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGE 128
                    + P  P  P     P +P  P+     G  G  GP       G P IG+ G 
Sbjct: 1343 GGGGFFGSSLPGPPGPPGPRGYPGIPG-PKGESIRGQPGPPGPQ------GPPGIGYEGR 1395

Query: 129  PPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAG 184
              P  PP P   P    P P    +  P P    P P    P  P PP      +G
Sbjct: 1396 QGPPGPPGPPGPPSF--PGPHRQTISVPGP----PGP----PGPPGPPGTMGASSG 1441



 Score = 37.7 bits (86), Expect = 0.012
 Identities = 59/229 (25%), Positives = 71/229 (31%), Gaps = 53/229 (23%)

Query: 20   LPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPG--------GGSGS----------DTKGG 61
            LP  P    PP        G PG P P G PG        G  GS           +KG 
Sbjct: 936  LPGVPGREGPP--------GFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA 987

Query: 62   GSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDE-DGAAGEAGPVSKAAAG-- 118
              PA        A    P  P  P  P  P  P  P   D+ +G+ G     +++A G  
Sbjct: 988  PGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQ 1047

Query: 119  GAPHI-GFVGEPPPYAPPDPKAAPLL--YPPFPQVP-------------------VVLQP 156
            G P + G  G+P     P  K        P FP +P                       P
Sbjct: 1048 GPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDP 1107

Query: 157  APSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNG--PMAGVPGPA 203
                +  P     P  P P    S   G+    P   G    AG PGPA
Sbjct: 1108 GKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPA 1156



 Score = 33.9 bits (76), Expect = 0.17
 Identities = 46/186 (24%), Positives = 57/186 (30%), Gaps = 13/186 (6%)

Query: 39   GEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPR 98
            G+PG P P G PG       + G   + P     P     P                 P 
Sbjct: 1113 GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPG 1172

Query: 99   TLDEDGAAG-----EAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVV 153
               E G  G     + G +  A  G     GF G P PY  P  K   + +P  P  P +
Sbjct: 1173 PKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYK-GEIGFPGRPGRPGM 1231

Query: 154  LQPAPSALFPPPAQL------YPAAPTPPALFSPPAGAAFPFPVY-NGPMAGVPGPATVE 206
                     P  A L       P  P PP    PP    +   V+      G PG    +
Sbjct: 1232 NGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQ 1291

Query: 207  HRPLPK 212
              P PK
Sbjct: 1292 GPPGPK 1297



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 19/40 (47%), Positives = 20/40 (50%), Gaps = 3/40 (7%)

Query: 19   PLPAAPPSRTPP--QTLKHL-PSGEPGPPFPAGMPGGGSG 55
            P P  PPS   P  QT+    P G PGPP P G  G  SG
Sbjct: 1402 PGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSG 1441


>gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Homo
           sapiens]
          Length = 1336

 Score = 61.6 bits (148), Expect = 8e-10
 Identities = 46/127 (36%), Positives = 52/127 (40%), Gaps = 16/127 (12%)

Query: 37  PSGEPGPPFPAGMPG--------GGSGSDTKG-GGSPATPEDPRSPAKPAAPEDPQMPAQ 87
           P G PGPP P G+PG        G + SD  G  G P  P     P  P  P  P  P +
Sbjct: 486 PRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGR 545

Query: 88  PALPQLPRRPRTLDEDGAAGEAGPVSKAA---AGGAPHIGFVGEPPPYAPPDPKAAPLLY 144
              P    +  +L E GA G  G  SK A   AG     G  G P P  PP P   P   
Sbjct: 546 EGPPGRTGQKGSLGEAGAPGHKG--SKGAPGPAGARGESGLAGAPGPAGPPGPPGPP--G 601

Query: 145 PPFPQVP 151
           PP P +P
Sbjct: 602 PPGPGLP 608



 Score = 58.9 bits (141), Expect = 5e-09
 Identities = 58/195 (29%), Positives = 72/195 (36%), Gaps = 12/195 (6%)

Query: 37   PSGEPGPPFPAGMPGGGSG--SDTKGGGSPATPEDPRSPAKPAAPED---PQMPAQPALP 91
            P G PGPP P G P   S   +++   G P  P +   P    A  +   P  P Q    
Sbjct: 841  PPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFD 900

Query: 92   QLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGE--PPPYAPPDPKAAPLLYPPFPQ 149
             L        E G  G+AG   +    G    GF G   P P  PP P+  P +  P  +
Sbjct: 901  FLQLEAEMKGEKGDRGDAGQKGERGEPGGG--GFFGSSLPGPPGPPGPRGYPGIPGPKGE 958

Query: 150  VPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVPGPATVEHRP 209
              +  QP P     PP   Y     PP    PP   +FP P  +     VPGP      P
Sbjct: 959  -SIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGP--HRQTISVPGPPGPPGPP 1015

Query: 210  LPKDYMMESVLVTLF 224
             P   M  S  V L+
Sbjct: 1016 GPPGTMGASSGVRLW 1030



 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 63/227 (27%), Positives = 76/227 (33%), Gaps = 62/227 (27%)

Query: 19  PLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGG----------------G 62
           P PA PP           P G PGPP P G+P G    +  GG                G
Sbjct: 588 PGPAGPPG----------PPGPPGPPGP-GLPAGFDDMEGSGGPFWSTARSADGPQGPPG 636

Query: 63  SPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPH 122
            P    DP  P  P A  +      P  P LP R       G  G+ G   +    G   
Sbjct: 637 LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG 696

Query: 123 IGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPS-----ALFPPPA----------Q 167
           +G  G P P  PP     P++Y       V+  P P      A FP PA          +
Sbjct: 697 VGQPGLPGPPGPP----GPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGE 752

Query: 168 LYPAAP-----TPPALFSPPAGAAFPF-------PVYNGPMAGVPGP 202
                P      P ++FSP  GA  P        P + GP    PGP
Sbjct: 753 RGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGP----PGP 795



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 54/194 (27%), Positives = 62/194 (31%), Gaps = 30/194 (15%)

Query: 39  GEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRR-- 96
           G PGPP  AG PG        G   P +P  P  PA    P     P  P     P R  
Sbjct: 346 GVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDG 405

Query: 97  -PRTLDEDGAAGEAGP---------VSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYPP 146
            P    EDG  G+ GP         V      G P +G  G P P  PP P      +  
Sbjct: 406 EPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDK 465

Query: 147 FPQVPV----------VLQPAPSALFPPPAQLYPAAPTPPALF-----SPPAGAAFP-FP 190
              + +           L+       PP     P  P  P  F       P  A  P  P
Sbjct: 466 LTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVP 525

Query: 191 VYNGP--MAGVPGP 202
              GP    G+PGP
Sbjct: 526 GREGPPGFPGLPGP 539



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 46/176 (26%), Positives = 55/176 (31%), Gaps = 31/176 (17%)

Query: 21   PAAPPSRTPPQTLKHLPSGEPGPPFPAGM----------PGGGSGSDTKGGGSPATPEDP 70
            P  P ++ PP        GE GPP P G              G   D    G      +P
Sbjct: 870  PGLPGNQGPPGPKG--AKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEP 927

Query: 71   RSPA--KPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGE 128
                    + P  P  P     P +P  P+     G  G  GP       G P IG+ G 
Sbjct: 928  GGGGFFGSSLPGPPGPPGPRGYPGIPG-PKGESIRGQPGPPGPQ------GPPGIGYEGR 980

Query: 129  PPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAG 184
              P  PP P   P    P P    +  P P    P P    P  P PP      +G
Sbjct: 981  QGPPGPPGPPGPPSF--PGPHRQTISVPGP----PGP----PGPPGPPGTMGASSG 1026



 Score = 37.7 bits (86), Expect = 0.012
 Identities = 59/229 (25%), Positives = 71/229 (31%), Gaps = 53/229 (23%)

Query: 20  LPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPG--------GGSGS----------DTKGG 61
           LP  P    PP        G PG P P G PG        G  GS           +KG 
Sbjct: 521 LPGVPGREGPP--------GFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA 572

Query: 62  GSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDE-DGAAGEAGPVSKAAAG-- 118
             PA        A    P  P  P  P  P  P  P   D+ +G+ G     +++A G  
Sbjct: 573 PGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQ 632

Query: 119 GAPHI-GFVGEPPPYAPPDPKAAPLL--YPPFPQVP-------------------VVLQP 156
           G P + G  G+P     P  K        P FP +P                       P
Sbjct: 633 GPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDP 692

Query: 157 APSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNG--PMAGVPGPA 203
               +  P     P  P P    S   G+    P   G    AG PGPA
Sbjct: 693 GKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPA 741



 Score = 33.9 bits (76), Expect = 0.17
 Identities = 46/186 (24%), Positives = 57/186 (30%), Gaps = 13/186 (6%)

Query: 39  GEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPR 98
           G+PG P P G PG       + G   + P     P     P                 P 
Sbjct: 698 GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPG 757

Query: 99  TLDEDGAAG-----EAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVV 153
              E G  G     + G +  A  G     GF G P PY  P  K   + +P  P  P +
Sbjct: 758 PKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYK-GEIGFPGRPGRPGM 816

Query: 154 LQPAPSALFPPPAQL------YPAAPTPPALFSPPAGAAFPFPVY-NGPMAGVPGPATVE 206
                    P  A L       P  P PP    PP    +   V+      G PG    +
Sbjct: 817 NGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQ 876

Query: 207 HRPLPK 212
             P PK
Sbjct: 877 GPPGPK 882



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 19/40 (47%), Positives = 20/40 (50%), Gaps = 3/40 (7%)

Query: 19   PLPAAPPSRTPP--QTLKHL-PSGEPGPPFPAGMPGGGSG 55
            P P  PPS   P  QT+    P G PGPP P G  G  SG
Sbjct: 987  PGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSG 1026


>gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Homo
           sapiens]
          Length = 1516

 Score = 61.6 bits (148), Expect = 8e-10
 Identities = 46/127 (36%), Positives = 52/127 (40%), Gaps = 16/127 (12%)

Query: 37  PSGEPGPPFPAGMPG--------GGSGSDTKG-GGSPATPEDPRSPAKPAAPEDPQMPAQ 87
           P G PGPP P G+PG        G + SD  G  G P  P     P  P  P  P  P +
Sbjct: 666 PRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGR 725

Query: 88  PALPQLPRRPRTLDEDGAAGEAGPVSKAA---AGGAPHIGFVGEPPPYAPPDPKAAPLLY 144
              P    +  +L E GA G  G  SK A   AG     G  G P P  PP P   P   
Sbjct: 726 EGPPGRTGQKGSLGEAGAPGHKG--SKGAPGPAGARGESGLAGAPGPAGPPGPPGPP--G 781

Query: 145 PPFPQVP 151
           PP P +P
Sbjct: 782 PPGPGLP 788



 Score = 58.9 bits (141), Expect = 5e-09
 Identities = 58/195 (29%), Positives = 72/195 (36%), Gaps = 12/195 (6%)

Query: 37   PSGEPGPPFPAGMPGGGSG--SDTKGGGSPATPEDPRSPAKPAAPED---PQMPAQPALP 91
            P G PGPP P G P   S   +++   G P  P +   P    A  +   P  P Q    
Sbjct: 1021 PPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFD 1080

Query: 92   QLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGE--PPPYAPPDPKAAPLLYPPFPQ 149
             L        E G  G+AG   +    G    GF G   P P  PP P+  P +  P  +
Sbjct: 1081 FLQLEAEMKGEKGDRGDAGQKGERGEPGGG--GFFGSSLPGPPGPPGPRGYPGIPGPKGE 1138

Query: 150  VPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVPGPATVEHRP 209
              +  QP P     PP   Y     PP    PP   +FP P  +     VPGP      P
Sbjct: 1139 -SIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGP--HRQTISVPGPPGPPGPP 1195

Query: 210  LPKDYMMESVLVTLF 224
             P   M  S  V L+
Sbjct: 1196 GPPGTMGASSGVRLW 1210



 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 63/227 (27%), Positives = 76/227 (33%), Gaps = 62/227 (27%)

Query: 19  PLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGG----------------G 62
           P PA PP           P G PGPP P G+P G    +  GG                G
Sbjct: 768 PGPAGPPG----------PPGPPGPPGP-GLPAGFDDMEGSGGPFWSTARSADGPQGPPG 816

Query: 63  SPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPH 122
            P    DP  P  P A  +      P  P LP R       G  G+ G   +    G   
Sbjct: 817 LPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG 876

Query: 123 IGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPS-----ALFPPPA----------Q 167
           +G  G P P  PP     P++Y       V+  P P      A FP PA          +
Sbjct: 877 VGQPGLPGPPGPP----GPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGE 932

Query: 168 LYPAAP-----TPPALFSPPAGAAFPF-------PVYNGPMAGVPGP 202
                P      P ++FSP  GA  P        P + GP    PGP
Sbjct: 933 RGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGP----PGP 975



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 54/194 (27%), Positives = 62/194 (31%), Gaps = 30/194 (15%)

Query: 39  GEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRR-- 96
           G PGPP  AG PG        G   P +P  P  PA    P     P  P     P R  
Sbjct: 526 GVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDG 585

Query: 97  -PRTLDEDGAAGEAGP---------VSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYPP 146
            P    EDG  G+ GP         V      G P +G  G P P  PP P      +  
Sbjct: 586 EPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDK 645

Query: 147 FPQVPV----------VLQPAPSALFPPPAQLYPAAPTPPALF-----SPPAGAAFP-FP 190
              + +           L+       PP     P  P  P  F       P  A  P  P
Sbjct: 646 LTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVP 705

Query: 191 VYNGP--MAGVPGP 202
              GP    G+PGP
Sbjct: 706 GREGPPGFPGLPGP 719



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 46/176 (26%), Positives = 55/176 (31%), Gaps = 31/176 (17%)

Query: 21   PAAPPSRTPPQTLKHLPSGEPGPPFPAGM----------PGGGSGSDTKGGGSPATPEDP 70
            P  P ++ PP        GE GPP P G              G   D    G      +P
Sbjct: 1050 PGLPGNQGPPGPKG--AKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEP 1107

Query: 71   RSPA--KPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGE 128
                    + P  P  P     P +P  P+     G  G  GP       G P IG+ G 
Sbjct: 1108 GGGGFFGSSLPGPPGPPGPRGYPGIPG-PKGESIRGQPGPPGPQ------GPPGIGYEGR 1160

Query: 129  PPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAG 184
              P  PP P   P    P P    +  P P    P P    P  P PP      +G
Sbjct: 1161 QGPPGPPGPPGPPSF--PGPHRQTISVPGP----PGP----PGPPGPPGTMGASSG 1206



 Score = 37.7 bits (86), Expect = 0.012
 Identities = 59/229 (25%), Positives = 71/229 (31%), Gaps = 53/229 (23%)

Query: 20  LPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPG--------GGSGS----------DTKGG 61
           LP  P    PP        G PG P P G PG        G  GS           +KG 
Sbjct: 701 LPGVPGREGPP--------GFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGA 752

Query: 62  GSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDE-DGAAGEAGPVSKAAAG-- 118
             PA        A    P  P  P  P  P  P  P   D+ +G+ G     +++A G  
Sbjct: 753 PGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQ 812

Query: 119 GAPHI-GFVGEPPPYAPPDPKAAPLL--YPPFPQVP-------------------VVLQP 156
           G P + G  G+P     P  K        P FP +P                       P
Sbjct: 813 GPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDP 872

Query: 157 APSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNG--PMAGVPGPA 203
               +  P     P  P P    S   G+    P   G    AG PGPA
Sbjct: 873 GKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPA 921



 Score = 33.9 bits (76), Expect = 0.17
 Identities = 46/186 (24%), Positives = 57/186 (30%), Gaps = 13/186 (6%)

Query: 39   GEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPR 98
            G+PG P P G PG       + G   + P     P     P                 P 
Sbjct: 878  GQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPG 937

Query: 99   TLDEDGAAG-----EAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVV 153
               E G  G     + G +  A  G     GF G P PY  P  K   + +P  P  P +
Sbjct: 938  PKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYK-GEIGFPGRPGRPGM 996

Query: 154  LQPAPSALFPPPAQL------YPAAPTPPALFSPPAGAAFPFPVY-NGPMAGVPGPATVE 206
                     P  A L       P  P PP    PP    +   V+      G PG    +
Sbjct: 997  NGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQ 1056

Query: 207  HRPLPK 212
              P PK
Sbjct: 1057 GPPGPK 1062



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 19/40 (47%), Positives = 20/40 (50%), Gaps = 3/40 (7%)

Query: 19   PLPAAPPSRTPP--QTLKHL-PSGEPGPPFPAGMPGGGSG 55
            P P  PPS   P  QT+    P G PGPP P G  G  SG
Sbjct: 1167 PGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSG 1206


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 53/172 (30%), Positives = 60/172 (34%), Gaps = 11/172 (6%)

Query: 38   SGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRP 97
            +GEPG P   G PG       KG   P+    P  P  P   + P+    P     P  P
Sbjct: 1290 AGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPK--GSPGPVGFPGDP 1347

Query: 98   RTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAP-LLYPPFPQVPVVLQP 156
                E G AG+ GP       G P  G  G P P   P P   P    PP P  P   Q 
Sbjct: 1348 GPPGEPGPAGQDGPPGDKGDDGEP--GQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQG 1405

Query: 157  APSA-----LFPPPAQLYPAAPT-PPALFSPPAGAAFPFPVYNGPMAGVPGP 202
               A     L  PP +  P  P   P    P      P PV    + G PGP
Sbjct: 1406 EKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGP 1457



 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 55/191 (28%), Positives = 66/191 (34%), Gaps = 23/191 (12%)

Query: 37   PSGEPGPPFPAGM------PGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMP----A 86
            P G PGPP P G+      PG    +   G   P  P  PR P+     + PQ P     
Sbjct: 1217 PRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIG 1276

Query: 87   QPALPQLPRRPRTLDEDGAAGEAGPV----SKAAAGGAPHIGFVGEPPPYAPP---DPKA 139
             P        P    E G  GE GP      +   G +   G  G P P  PP    PK 
Sbjct: 1277 NPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKG 1336

Query: 140  A--PLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGPMA 197
            +  P+ +P  P  P   +P P+    PP          P     P     P P       
Sbjct: 1337 SPGPVGFPGDPGPPG--EPGPAGQDGPPGD--KGDDGEPGQTGSPGPTGEPGPSGPPGKR 1392

Query: 198  GVPGPATVEHR 208
            G PGPA  E R
Sbjct: 1393 GPPGPAGPEGR 1403



 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 42/125 (33%), Positives = 46/125 (36%), Gaps = 7/125 (5%)

Query: 21   PAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPA-TPEDPRSPAKPAAP 79
            P  P   T P   +  P G PGPP   G+PG      TKG   PA  P     P     P
Sbjct: 1001 PQGPTGETGPMGERGHP-GPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFP 1059

Query: 80   EDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDP-- 137
             D  +P       L          G AG  G   +  AG A  IG  G P P  PP P  
Sbjct: 1060 GDRGLPGPVGALGLKGNEGPPGPPGPAGSPG--ERGPAGAAGPIGIPGRPGPQGPPGPAG 1117

Query: 138  -KAAP 141
             K AP
Sbjct: 1118 EKGAP 1122



 Score = 52.0 bits (123), Expect = 6e-07
 Identities = 56/185 (30%), Positives = 62/185 (33%), Gaps = 33/185 (17%)

Query: 37   PSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQ---- 92
            P GE GP    G PG    S   GG  PA P   R P  P  P     P  P  P     
Sbjct: 917  PRGERGPRGITGKPGPKGNS---GGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDG 973

Query: 93   LPRRPRTLDEDGAAGEAGPVS-------KAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYP 145
            LP  P    E G  G+ GP         +   G    +G  G P P  PP  +  P L  
Sbjct: 974  LPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGL-- 1031

Query: 146  PFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPV-------YNGPMAG 198
               +      P P+ L        P    PP L   P     P PV         GP  G
Sbjct: 1032 -AGKEGTKGDPGPAGL--------PGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGP-PG 1081

Query: 199  VPGPA 203
             PGPA
Sbjct: 1082 PPGPA 1086



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 38/119 (31%), Positives = 45/119 (37%), Gaps = 14/119 (11%)

Query: 37   PSGEPGPPFPAGMPG--------GGSGS-DTKGGGSPATPEDPRSPAKPAAPEDPQ---- 83
            P GEPGP    G PG        G +GS    G   P+ P   R P  PA PE  Q    
Sbjct: 1349 PPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKG 1408

Query: 84   MPAQPALPQLPRRPRTLDEDGAAGEAGPVS-KAAAGGAPHIGFVGEPPPYAPPDPKAAP 141
               +  L   P +   +   GA G+ GP   +   G     G  G P P  PP P   P
Sbjct: 1409 AKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPP 1467



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 55/190 (28%), Positives = 62/190 (32%), Gaps = 28/190 (14%)

Query: 19   PLPAAPPSRTPPQTLKHLPS--GEPGPPFPAGMPGGGSGSDTKGG-GSPATPEDPRSPAK 75
            P P  PP       +  LP   G  GP    G PG    +  KGG G+P  P  PR    
Sbjct: 855  PGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKP-GPRGQRG 913

Query: 76   PAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPP 135
            P  P   + P                  G  G+ GP  K  +GG    G  GE  P  P 
Sbjct: 914  PTGPRGERGPR-----------------GITGKPGP--KGNSGGDGPAGPPGERGPNGPQ 954

Query: 136  DPKAAP-LLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSP--PAGAAFPFPVY 192
             P   P    PP P     L   P        Q     P PP +  P  P G   P    
Sbjct: 955  GPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGER 1014

Query: 193  NGPMAGVPGP 202
              P  G PGP
Sbjct: 1015 GHP--GPPGP 1022



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 52/184 (28%), Positives = 64/184 (34%), Gaps = 14/184 (7%)

Query: 29   PPQTLKHLPSGEPGPPFPAGM--PGGGSGSD----TKGGGSPATPEDPRSPAKPAAPEDP 82
            P QT    P+GEPGP  P G   P G +G +     KG    A  E P     P  P+  
Sbjct: 1371 PGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQG- 1429

Query: 83   QMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHI-GFVGEPPPYAPP-DPKAA 140
              P +P    L   P  + E G  G  GP       G P + G  G+  P      P   
Sbjct: 1430 -APGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLI 1488

Query: 141  PLLYPPFPQVPVVLQ--PAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGPMAG 198
             L+ PP  Q     +  P P     P  +     P+ P    PP     P P       G
Sbjct: 1489 GLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGP--IGPPGPPGLPGPPGPKGAKG 1546

Query: 199  VPGP 202
              GP
Sbjct: 1547 SSGP 1550



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 63/221 (28%), Positives = 73/221 (33%), Gaps = 39/221 (17%)

Query: 19  PLPAAPPSRT-----PPQTLKHLPSGEPGPPFPAGMPG--------GGSGSDTKGG--GS 63
           P P  PP  T     P       P GEPGPP   G PG        G  G   + G  G 
Sbjct: 690 PGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGK 749

Query: 64  PATPEDPRSPAKPAAPEDPQMPAQ-----PALPQLP---RRPRTL-DEDGAAGEAGPVSK 114
           P  P  P +   P  P     P +     P  PQ P     PR +   DG  G  G   +
Sbjct: 750 PGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGE 809

Query: 115 AAAGGAP----HIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQ--- 167
               G P     +G  G+     PP P+      P  P+        P  L PP  +   
Sbjct: 810 KGEDGFPGFKGDMGIKGDRGEIGPPGPRGED--GPEGPKGRGGPNGDPGPLGPPGEKGKL 867

Query: 168 LYPAAPTPPALFSPPAGAAFP-FPVYNGPMA-----GVPGP 202
             P  P  P    P     FP FP  NG        G PGP
Sbjct: 868 GVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGP 908



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 24/66 (36%), Positives = 28/66 (42%), Gaps = 1/66 (1%)

Query: 37   PSGEPGPPFPAGMPGGGSGSDTKGGGSPATPE-DPRSPAKPAAPEDPQMPAQPALPQLPR 95
            PSG  GPP P G+PG       KG   P  P+ +   P  P  P  P    QP   Q  R
Sbjct: 1523 PSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLPIQASR 1582

Query: 96   RPRTLD 101
              R +D
Sbjct: 1583 TRRNID 1588



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 59/220 (26%), Positives = 68/220 (30%), Gaps = 42/220 (19%)

Query: 19   PLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATP------EDPRS 72
            P PA  P    P      P G PG P P G PG        G   P  P      + P  
Sbjct: 1083 PGPAGSPGERGPAGAAG-PIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVG 1141

Query: 73   PAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPY 132
               PA P  P  P +         P      G  GE GP       G      +G+P P 
Sbjct: 1142 LPGPAGPVGP--PGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGP-----IGQPGPS 1194

Query: 133  ---APPDPKAAPLLYP----------PFPQVPVVLQPAPSALFPP--------PAQLYPA 171
                 P P+    L+           P P  PV LQ  P    PP          Q+ P 
Sbjct: 1195 GADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPG---PPGEKGETGDVGQMGPP 1251

Query: 172  APTPPALFSPPAGAAFPFPVYNGPMAGVPGPATVEHRPLP 211
             P  P   S   GA  P     GP  G+  P  V  +  P
Sbjct: 1252 GPPGPRGPSGAPGADGP----QGPPGGIGNPGAVGEKGEP 1287



 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 39/116 (33%), Positives = 45/116 (38%), Gaps = 21/116 (18%)

Query: 36  LPSGEPGPPFPAGMPG-GGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLP 94
           L  G PGP  PAG+PG  G+   T   G P     P  P  P A   P  P    +  LP
Sbjct: 466 LIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPG--TMLMLP 523

Query: 95  RRPRTLDEDGAAGEAGPV-----SKAAA----------GGAPHIGFVGEPPPYAPP 135
            R       G AG  GP+     S+A A          G A  +G  G P P  PP
Sbjct: 524 FR---FGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPP 576



 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 48/186 (25%), Positives = 55/186 (29%), Gaps = 34/186 (18%)

Query: 37  PSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRR 96
           P G  G P P G PG G      G   P  P   + P  PA                P R
Sbjct: 563 PMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGK--------------PGR 608

Query: 97  PRTLDEDGA---AGEAGPVSKAAAGGAPHI----GFVGEPPPYAPPDP-----------K 138
                 DGA    G+ GP       G   +    G  G+P P  PP P           +
Sbjct: 609 RGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGE 668

Query: 139 AAPLLYPPFPQVPVVLQP--APSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGPM 196
             P   P  P    +L P   P    PP        P P     P      P    N   
Sbjct: 669 VGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGA 728

Query: 197 AGVPGP 202
            G+PGP
Sbjct: 729 QGLPGP 734



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 40/129 (31%), Positives = 47/129 (36%), Gaps = 15/129 (11%)

Query: 37   PSGEPGPPFPAGMPGGGSGSDTKG-GGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPR 95
            P G PGP  P G+PG    S  KG  G P        P +     D  +P     PQ   
Sbjct: 1457 PDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPG----PQGSS 1512

Query: 96   RPRTLDEDGAAGEAGPVSKAAAGGAP----HIGFVGEPPPYAPPDPKAAPLLYPPFPQVP 151
             P+   E G  G +GP+      G P      G  G   P  P      P   PP P  P
Sbjct: 1513 GPK--GEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHP--GPPGPPGP 1568

Query: 152  --VVLQPAP 158
               V+QP P
Sbjct: 1569 PGEVIQPLP 1577



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 48/172 (27%), Positives = 56/172 (32%), Gaps = 12/172 (6%)

Query: 37   PSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMP-AQPALPQLPR 95
            P G PGP  P G PG        G       +  +    P  P  PQ P  QP       
Sbjct: 1139 PVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADG 1198

Query: 96   RPRTLDEDGAAGEAGPVSKAAAGGAP-HIGFVGEP-PPYAPPDPKAAPLLYPPFPQVPVV 153
             P    + G  G+ G        G P  +G  G P PP    +      + PP P  P  
Sbjct: 1199 EPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRG 1258

Query: 154  LQPAPSALFP--PPAQLYPAAPTPPALFSPPAGAAFP-FPVYNGPMAGVPGP 202
               AP A  P  PP  +    P        P  A  P  P   GP    PGP
Sbjct: 1259 PSGAPGADGPQGPPGGI--GNPGAVGEKGEPGEAGEPGLPGEGGP----PGP 1304


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 48/164 (29%), Positives = 64/164 (39%), Gaps = 14/164 (8%)

Query: 19  PLPAAPPSRTPPQ-TLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPA 77
           P P  PP++  P     ++P   P PP P   P             P+      S  K  
Sbjct: 806 PTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQI 865

Query: 78  APEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDP 137
           A + P  P  PA+   P +P   +    A ++ P  KA     P    +  P P  PP P
Sbjct: 866 ASQFPPPPTPPAMESQPLKPVPAN---VAPQSPPAVKAKPKWQP--SSIPVPSPDFPPPP 920

Query: 138 KAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSP 181
             + L++PP P  PV   P P    PPP     A+PTP    SP
Sbjct: 921 PESSLVFPPPPPSPVPAPPPP----PPPT----ASPTPDKSGSP 956



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 62/225 (27%), Positives = 81/225 (36%), Gaps = 43/225 (19%)

Query: 19  PLPAAPPSRTPPQTLKHLPSG---EPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSP-- 73
           P P    S++    +   P+G    P PP P   PG           +P+ P+    P  
Sbjct: 687 PTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPP 746

Query: 74  ------------AKPAAPEDPQMPAQPALPQLPRRPR-TLDEDGAAGEAGPVSKAAAGGA 120
                       A P  P  P +PA P  PQ P +P  T+    +     PV   AA   
Sbjct: 747 LKIHQVQHITQVAPPTPPPPPPIPA-PLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPT 805

Query: 121 PHIGFVGE------PPPYAPPDPKAAPLLYPPFPQVP----VVLQPAPSALFPPP----- 165
           P             P  Y PP P   P+  PP P +P       +P PS L P P     
Sbjct: 806 PTPPVPPAKKQPAFPASYIPPSPPTPPVPVPP-PTLPKQQSFCAKPPPSPLSPVPSVVKQ 864

Query: 166 -AQLYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVPGPATVEHRP 209
            A  +P  PTPPA+ S P     P P    P +    P  V+ +P
Sbjct: 865 IASQFPPPPTPPAMESQPLK---PVPANVAPQS----PPAVKAKP 902



 Score = 55.1 bits (131), Expect = 7e-08
 Identities = 66/225 (29%), Positives = 79/225 (35%), Gaps = 40/225 (17%)

Query: 19  PLPAAPPSRTPPQTLKHLPSGEPGPPFPA-GMPGGGSGS------------DTKGGGSPA 65
           PLP  PP   PP      P   P PP P+   P  GS +                  S A
Sbjct: 627 PLPPPPPPPPPPPP----PPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGA 682

Query: 66  TPEDPRSPAKPAAPEDPQM--PAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAA---GGA 120
             + P  P   +    PQ+  P    +P  P  P       A  +  P   A +     A
Sbjct: 683 LFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSA 742

Query: 121 P----------HIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSA---LFPPPAQ 167
           P          HI  V  P P  PP P  APL  P  P  P+V  PAP++   + P   Q
Sbjct: 743 PPPPLKIHQVQHITQVAPPTP-PPPPPIPAPLP-PQAPPKPLVTIPAPTSTKTVAPVVTQ 800

Query: 168 LYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVPGPATVEHRPLPK 212
             P  PTPP    PPA     FP    P +    P  V    LPK
Sbjct: 801 AAPPTPTPPV---PPAKKQPAFPASYIPPSPPTPPVPVPPPTLPK 842



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 62/223 (27%), Positives = 82/223 (36%), Gaps = 48/223 (21%)

Query: 21  PAAPPSRTPPQTLK-----HL-----PSGEPGPPFPAGMPGGG---------SGSDTKG- 60
           P+ P    PP  LK     H+     P+  P PP PA +P            + + TK  
Sbjct: 735 PSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTV 794

Query: 61  -----GGSPATPEDPRSPAK--PAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVS 113
                  +P TP  P  PAK  PA P    +P  P  P +P  P TL +  +     P S
Sbjct: 795 APVVTQAAPPTPTPPVPPAKKQPAFPAS-YIPPSPPTPPVPVPPPTLPKQQSFCAKPPPS 853

Query: 114 KAAAGGAPHIGFVGE-PPPYAPPDPKAAPLLYPPF---PQVPVVLQ----------PAPS 159
             +   +       + PPP  PP  ++ PL   P    PQ P  ++          P PS
Sbjct: 854 PLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPS 913

Query: 160 ALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVPGP 202
             FPPP       P    +F PP  +  P P    P    P P
Sbjct: 914 PDFPPPP------PESSLVFPPPPPSPVPAPPPPPPPTASPTP 950



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 54/219 (24%), Positives = 72/219 (32%), Gaps = 39/219 (17%)

Query: 9   KQLREMLERWPLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPE 68
           K   E + R      PP    P+ +    + +P PP P   P             P  P 
Sbjct: 592 KARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPP------------PPPPPP 639

Query: 69  DPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGG--------- 119
            P  P  P  P      A  A P   +         A+  +G + K              
Sbjct: 640 PPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKP 699

Query: 120 ---APHIGFV-GEPPPYAPPDPKAAPLLYPPFPQVPVVLQ-PAPSALFPPPAQLYP---- 170
               P  G V   PPP  PP P +A     P P  P + Q  AP    PPP +++     
Sbjct: 700 QILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAP----PPPLKIHQVQHI 755

Query: 171 ---AAPTPPALFSPPAGAAFPFPVYNGPMAGVPGPATVE 206
              A PTPP    PP  A  P      P+  +P P + +
Sbjct: 756 TQVAPPTPPP--PPPIPAPLPPQAPPKPLVTIPAPTSTK 792



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 53/211 (25%), Positives = 73/211 (34%), Gaps = 34/211 (16%)

Query: 21   PAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGS--PATPEDPRSPAKPAA 78
            P  PPS  P       P+  P P   +G PG  +   +  GG   P TP+   S    + 
Sbjct: 928  PPPPPSPVPAPPPPPPPTASPTPD-KSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSG 986

Query: 79   PEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPK 138
             E P+ P +P++  L      + +     E+G  SK              PPP APP P 
Sbjct: 987  AEHPE-PKRPSVDSL------VSKFTPPAESGSPSKETL-----------PPPAAPPKPG 1028

Query: 139  AAPLLYPPFPQVPVVLQ--------PAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFP 190
               L       +P VLQ        P  S         +P+ P+      PP     P P
Sbjct: 1029 KLNL---SGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLP 1085

Query: 191  VYNGP--MAGVPGPATVEHRPLPKDYMMESV 219
                P   +G   P      P P+ +   SV
Sbjct: 1086 PIEIPAVFSGNTSPKVAVVNPQPQQWSKMSV 1116



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 46/200 (23%), Positives = 71/200 (35%), Gaps = 30/200 (15%)

Query: 5    SPICKQLREMLERWPLPAAPPSRTPPQTLKHLPS--GEPGPPFPAGMPGGGSGSDTKGGG 62
            SP+   ++++  ++P P  PP+    Q LK +P+      PP     P     S      
Sbjct: 856  SPVPSVVKQIASQFPPPPTPPA-MESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPV--P 912

Query: 63   SPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPH 122
            SP  P  P   +    P  P     P  P  P    T D+ G+ G+    + +  G  P 
Sbjct: 913  SPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKP- 971

Query: 123  IGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPP 182
                                  PP PQ    ++ +  A  P P +  P+  +  + F+PP
Sbjct: 972  ----------------------PPTPQRNSSIKSSSGAEHPEPKR--PSVDSLVSKFTPP 1007

Query: 183  AGAAFPFPVYNGPMAGVPGP 202
            A +  P      P A  P P
Sbjct: 1008 AESGSPSKETLPPPAAPPKP 1027



 Score = 35.8 bits (81), Expect = 0.045
 Identities = 34/127 (26%), Positives = 42/127 (33%), Gaps = 28/127 (22%)

Query: 111 PVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPS----------- 159
           P+S       P+      PP   PP P   P   PP P  P+  Q APS           
Sbjct: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667

Query: 160 --------------ALFPPPA-QLYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVPGPAT 204
                         ALF PP   +  +    P +  PP G   P P    P    PG A 
Sbjct: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPP--PPPPPPTPGSAM 725

Query: 205 VEHRPLP 211
            + +P P
Sbjct: 726 AQLKPAP 732



 Score = 35.4 bits (80), Expect = 0.058
 Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 2/70 (2%)

Query: 143 LYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVPGP 202
           L PP    P ++ P  ++   PP  L P  P PP    PP     P P  + P AG   P
Sbjct: 605 LVPPLSPQPKIVTPYTASQPSPP--LPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAP 662

Query: 203 ATVEHRPLPK 212
             V++  + +
Sbjct: 663 MFVKYSTITR 672


>gi|165905613 ring finger and KH domain containing 1 [Homo sapiens]
          Length = 651

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 60/171 (35%), Positives = 70/171 (40%), Gaps = 32/171 (18%)

Query: 44  PFPAGMPGGGSGSDTKGGGSPATPEDP---------------RSPAKPAAPEDPQMPAQP 88
           P   G P GG G    GGG  A  EDP                +P  P  P+D     + 
Sbjct: 2   PSSLGQPDGGGGGGGGGGGVGAAGEDPGPGPAPPPEGAQEAAPAPRPPPEPDDAAAALRL 61

Query: 89  ALPQLPR----RPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLY 144
           AL QL           DE+GAAG+      AAAGGA   G   EP P   P+  A P L 
Sbjct: 62  ALDQLSALGLGGAGDTDEEGAAGDGA----AAAGGADG-GAAPEPVPPDGPEAGAPPTLA 116

Query: 145 PPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGP 195
           P      + L   P+A  PPP    P  P+PP +F   AG A P P   GP
Sbjct: 117 PAVAPGSLPLLD-PNASPPPPP---PPRPSPPDVF---AGFA-PHPAALGP 159


>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
          Length = 684

 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 61/195 (31%), Positives = 69/195 (35%), Gaps = 34/195 (17%)

Query: 39  GEPGPPFPAGMPG--GGSGSDTKGG--GSPATPEDPRSPAKPAAPEDPQMPAQPALPQLP 94
           G PGPP P G PG  G  G D + G  G P  P    +P KP  P +  +P  P +  L 
Sbjct: 29  GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT 88

Query: 95  RRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEP-------PP-----YAPPDPKAAP- 141
            R       GA GE G +      G    G  G P       PP       PP P   P 
Sbjct: 89  GRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPG 148

Query: 142 LLYPPFPQVPVVLQPAPSALFPPPA-QLYPAAPTPPALFSPPAGAAFPFPV-YNGPMA-- 197
           L  PP P  P    P    + P  A  L   +  PP    PP    F  P  Y G     
Sbjct: 149 LPGPPGPPGP----PGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEV 204

Query: 198 ---------GVPGPA 203
                    G PGPA
Sbjct: 205 GKDGEKGDPGPPGPA 219



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 37/109 (33%), Positives = 42/109 (38%), Gaps = 12/109 (11%)

Query: 37  PSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRR 96
           PSGEPG P  AGMPG    +  +G      P+ P  P  P              P LP  
Sbjct: 362 PSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGP--PGAPGVRGFQGQKGSMGDPGLP-G 418

Query: 97  PRTLDED-------GAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPK 138
           P+ L  D       GAAG  G    A + G P  G  GE  P     PK
Sbjct: 419 PQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLP--GDKGELGPSGLVGPK 465



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 29/95 (30%), Positives = 37/95 (38%), Gaps = 9/95 (9%)

Query: 39  GEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPR 98
           G+PGPP PAG+PG       +G      P  P     P     P     P +P  P +  
Sbjct: 211 GDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGP-----PGIPGAPGKAG 265

Query: 99  TLDEDGAAGEAGP---VSKAAAGGAPHI-GFVGEP 129
              E G  G  GP   + +    G P + G  GEP
Sbjct: 266 DRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEP 300



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 32/101 (31%), Positives = 39/101 (38%), Gaps = 11/101 (10%)

Query: 37  PSGEPGPPFPAGMPG-----GGSGSDTKGG--GSPATPEDPRSPAKPAAPEDPQMPAQPA 89
           P G+ G P P G PG     G  G   K G  G P          +  AP +        
Sbjct: 278 PKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEK---GPNG 334

Query: 90  LPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHI-GFVGEP 129
           LP LP R  +  E G  G AG + +A   G P + G  G P
Sbjct: 335 LPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMP 375



 Score = 36.6 bits (83), Expect = 0.026
 Identities = 39/134 (29%), Positives = 48/134 (35%), Gaps = 18/134 (13%)

Query: 7   ICKQLREMLERWPLPAAPPSRTPPQTLKHLPSGEPGPPFPAGM---PGGGSGSDTKGGGS 63
           I +Q+ ++      P AP S   P      P+G PGPP P G    PG       +G   
Sbjct: 533 ISEQIAQLAAHLRKPLAPGSIGRPG-----PAGPPGPPGPPGSIGHPGARGPPGYRGPTG 587

Query: 64  PATPEDPR--------SPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKA 115
                 PR          A  A  + P+    P  PQ         +DGA GE GP    
Sbjct: 588 ELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDP 647

Query: 116 AAGGAPHIGFVGEP 129
              GA  IG  G P
Sbjct: 648 GLPGA--IGAQGTP 659



 Score = 33.9 bits (76), Expect = 0.17
 Identities = 27/118 (22%), Positives = 45/118 (38%), Gaps = 15/118 (12%)

Query: 39  GEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAK----PAAPEDPQMPAQPALPQLP 94
           G+ G   P+G+ G    S ++G   P   + P   +     P  P    +   P +P + 
Sbjct: 451 GDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGIT 510

Query: 95  RRPRTLDEDGAAGE-----AGPVSKAAAGGAPHI------GFVGEPPPYAPPDPKAAP 141
            +P    ++ +         G +S+  A  A H+      G +G P P  PP P   P
Sbjct: 511 GKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPP 568


>gi|57863314 vacuolar protein sorting 37C [Homo sapiens]
          Length = 355

 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 54/172 (31%), Positives = 63/172 (36%), Gaps = 22/172 (12%)

Query: 18  WPLPAAPPSRTPPQTLKHLPSGEPGPPFPA-GMPGGGSGSDTKGGGSPATPEDPRSPAKP 76
           +PLP +P    P     H     P  PFP    P   SG    G   PA    PR  A  
Sbjct: 203 YPLPYSPSPSLPVGPTAH--GALPPAPFPVVSQPSFYSGP--LGPTYPAAQLGPRGAAGY 258

Query: 77  AAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPD 136
           +      MP +P  P  P            G +GP      G AP  G+  +  PY    
Sbjct: 259 SWSPQRSMPPRPGYPGTPM-----------GASGPGYPLRGGRAPSPGYP-QQSPYPATG 306

Query: 137 PKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFP 188
            K    + P  P  P   QP PS    PP   YP  P PP  F PP G A+P
Sbjct: 307 GKPPYPIQPQLPSFPG--QPQPSVPLQPP---YPPGPAPPYGFPPPPGPAWP 353



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 57/203 (28%), Positives = 66/203 (32%), Gaps = 48/203 (23%)

Query: 23  APPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSP-AKPAAP-- 79
           APP R PP          P  P P G P             P   E P+ P A P  P  
Sbjct: 170 APPPRPPP----------PVRPVPQGTP-------------PVVEEQPQPPLAMPPYPLP 206

Query: 80  --EDPQMPAQP----ALPQLPRRPRTLDEDGAAGEAGPVSKAAA-GGAPHIGFVGEPPPY 132
               P +P  P    ALP  P  P        +G  GP   AA  G     G+   P   
Sbjct: 207 YSPSPSLPVGPTAHGALPPAPF-PVVSQPSFYSGPLGPTYPAAQLGPRGAAGYSWSPQRS 265

Query: 133 APPDPK-------AAPLLYP------PFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALF 179
            PP P        A+   YP      P P  P    P P+    PP  + P  P+ P   
Sbjct: 266 MPPRPGYPGTPMGASGPGYPLRGGRAPSPGYPQQ-SPYPATGGKPPYPIQPQLPSFPGQP 324

Query: 180 SPPAGAAFPFPVYNGPMAGVPGP 202
            P      P+P    P  G P P
Sbjct: 325 QPSVPLQPPYPPGPAPPYGFPPP 347



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 35/113 (30%), Positives = 46/113 (40%), Gaps = 30/113 (26%)

Query: 90  LPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYPPFPQ 149
           L ++ R+PR   E   AG+A P                 PPP   P P+  P +    PQ
Sbjct: 153 LQEVVRKPRASQE--LAGDAPPP---------------RPPPPVRPVPQGTPPVVEEQPQ 195

Query: 150 VPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPV------YNGPM 196
            P+ + P P    P P+   P  PT      PPA    PFPV      Y+GP+
Sbjct: 196 PPLAMPPYPLPYSPSPS--LPVGPTAHGAL-PPA----PFPVVSQPSFYSGPL 241


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 58.5 bits (140), Expect = 6e-09
 Identities = 55/169 (32%), Positives = 64/169 (37%), Gaps = 31/169 (18%)

Query: 21   PAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPE 80
            P  PP+  PP  L HLP   P PP P G                    + R PAKP  P 
Sbjct: 1193 PPPPPAEPPPTDLAHLP---PLPP-PEG--------------------EARKPAKP--PV 1226

Query: 81   DPQMPAQPALPQLPRRPR-TLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKA 139
             P+      +P+L   P  T  +    G   P  K A G  P +     PPP AP   KA
Sbjct: 1227 SPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKA 1286

Query: 140  APLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFP 188
               L    P       PAPS    PPA L     TPP+L + PA    P
Sbjct: 1287 VAGL----PSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSP 1331



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 49/173 (28%), Positives = 63/173 (36%), Gaps = 13/173 (7%)

Query: 2   GRTSPICKQLREMLERWPLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGG 61
           G +SP+ +    +L+  P P  PP    P    H       PP P G P       T   
Sbjct: 716 GPSSPMSRSQEYLLDEGPAPGTPPREARPGRHGHSIKRASVPPVP-GKPRQVLPPGTSHF 774

Query: 62  GSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAP 121
             P TP   R P  P A   P  PA PA  ++   P+ L          P+S  +   +P
Sbjct: 775 TPPQTPTKTR-PGSPQALGGPHGPA-PATAKVKPTPQLLPP-----TERPMSPRSLPQSP 827

Query: 122 -HIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAP 173
            H GF    P   P + +  P    P P  P V    P+   PP A   P  P
Sbjct: 828 THRGFAYVLP--QPVEGEVGPA--APGPAPPPVPTAVPTLCLPPEADAEPGRP 876



 Score = 34.7 bits (78), Expect = 0.100
 Identities = 36/115 (31%), Positives = 45/115 (39%), Gaps = 20/115 (17%)

Query: 19   PLPAAPPSR----TPPQTLKHLPSGEPGPPFP----AGMPGGGSGSDTKGGGSPATPEDP 70
            P P +P  +    TPP  +   P   P  P P    AG+P G +G       SPA  + P
Sbjct: 1253 PGPGSPEVKRAHGTPP-PVSPKPPPPPTAPKPVKAVAGLPSGSAGPSP--APSPAR-QPP 1308

Query: 71   RSPAKP--------AAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAA 117
             + AKP        A+P  P  P  PAL    + PR      AA  A P     A
Sbjct: 1309 AALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGA 1363



 Score = 34.3 bits (77), Expect = 0.13
 Identities = 51/214 (23%), Positives = 67/214 (31%), Gaps = 46/214 (21%)

Query: 24  PPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQ 83
           P  R  PQ+L+ +    P PP P       S   T    S  + E   +   PA      
Sbjct: 617 PLRRKAPQSLEVMAIESPPPPEPTPADCQ-SPKMTTFQDSELSDELQAAMTGPAEVGPTT 675

Query: 84  MPAQPALPQLPRRPRTLDE-----------------DGAAGEAGPVSKAAA-----GGAP 121
                 LP  PR     D                  DG  G + P+S++       G AP
Sbjct: 676 EKPSSHLPPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGPAP 735

Query: 122 HIGFVGEPPPYAPPDPKAAPLL---YPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPAL 178
                G PP  A P      +     PP P  P  + P  ++ F PP       P  P  
Sbjct: 736 -----GTPPREARPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPGSPQA 790

Query: 179 FSPPAGAAFPFPVYNGPMAGVPGPATVEHRPLPK 212
              P G               P PAT + +P P+
Sbjct: 791 LGGPHG---------------PAPATAKVKPTPQ 809



 Score = 33.9 bits (76), Expect = 0.17
 Identities = 57/229 (24%), Positives = 75/229 (32%), Gaps = 43/229 (18%)

Query: 19   PLPAAP-PSR--TPPQTLKHLPSGEPGPPFP------AGMPGGGSGSDTKGGGSPATP-- 67
            P PA+P P R  T   ++KH  +  PG          +G   G   +  +G G  A P  
Sbjct: 1030 PRPASPEPGRVATVLASVKHKEAIGPGGEVVNRRRTLSGPVTGLLATARRGPGESADPGP 1089

Query: 68   --------EDPRSPAK-PAAPEDPQMPAQPALPQLPRRPRT-----------LDEDGAAG 107
                    + PR P+K  A  E P +    A   L RR R            L E     
Sbjct: 1090 FVEDGTGRQRPRGPSKGEAGVEGPPLAKVEASATLKRRIRAKQNQQENVKFILTESDTVK 1149

Query: 108  EAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAPLLYPPFPQV--PVVLQPAPSALFPPP 165
                  +  AG  P       PPP +        +   P  +   P  L P P    PPP
Sbjct: 1150 RRPKAKEREAGPEP-------PPPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPP 1202

Query: 166  AQLYPAAPTPP---ALFSPPAGAAFPFPVYNGPMAGVPGPATVEHRPLP 211
              L    P PP       P      P PV   P+  + G  T   + +P
Sbjct: 1203 TDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVP 1251


>gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo
           sapiens]
          Length = 921

 Score = 58.2 bits (139), Expect = 8e-09
 Identities = 54/176 (30%), Positives = 60/176 (34%), Gaps = 31/176 (17%)

Query: 24  PPSRTPPQTLKHL-PSGEPGPPFPAGMPG--GGSGSDTKGG--GSPATPEDPRSPAKPAA 78
           P   TP QT     P GE GPP P G PG  G  G D   G  G P  P     P KP A
Sbjct: 256 PARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGA 315

Query: 79  PEDPQMPAQPALPQLPRRPRTLDEDGAAGE--------------AGPVSKAAAGGAP--- 121
           P  P  P    L      P ++   G  GE               GP       G P   
Sbjct: 316 PGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGEL 375

Query: 122 -HIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVL---QPAPSALFPPPAQLYPAAP 173
             +G VG+P    PP P       PP P+  +      P      PP    YP  P
Sbjct: 376 GRVGPVGDPGRRGPPGPPG-----PPGPRGTIGFHDGDPLCPNACPPGRSGYPGLP 426



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 45/160 (28%), Positives = 56/160 (35%), Gaps = 10/160 (6%)

Query: 19  PLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAA 78
           P  A P      +  + +P G PGP    G+PG   G D    G P  P     P KP  
Sbjct: 510 PGEAGPKGDRGAEGARGIP-GLPGPKGDTGLPGV-DGRD----GIPGMPGTKGEPGKPGP 563

Query: 79  PEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPK 138
           P D  +   P +P +P       E G+ G  G   +    G P  G  G P    P  P+
Sbjct: 564 PGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKP--GQQGPPGEVGPRGPQ 621

Query: 139 AAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPAL 178
             P         PV     P  L    +   P  P PP L
Sbjct: 622 GLPGSRGELG--PVGSPGLPGKLGSLGSPGLPGLPGPPGL 659



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 57/214 (26%), Positives = 70/214 (32%), Gaps = 48/214 (22%)

Query: 37  PSGEPGPPFPAGMPGG-GSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPR 95
           P GE GP  P G+PG  G        G P       SP  P  P  P +P       +  
Sbjct: 611 PPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVG 670

Query: 96  RPRTLDEDGAAGEAG-------------PVSKAAAG--GAPHI-------GFVGEPPPYA 133
            P    E GA+GE G             P  K +AG  G P +       G  G   P  
Sbjct: 671 EPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRG 730

Query: 134 PPDPKAA---------PLLYPPFPQVPV----------VLQP-----APSALFPPP-AQL 168
           PP P+           P +  P  + P           V+Q      A S   P   A  
Sbjct: 731 PPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATG 790

Query: 169 YPAAPTPPALFSPPAGAAFPFPVYNGPMAGVPGP 202
            P  P PP    PP    FP  +    + G+ GP
Sbjct: 791 LPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGP 824



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 42/151 (27%), Positives = 48/151 (31%), Gaps = 30/151 (19%)

Query: 81  DPQMPAQPALPQLPRR---PRTLDEDGAAGEAGPVSKAAAGGAPHI-GFVGEPPPYAPPD 136
           DP  P +    +LP R    +T DE G  GE GP       G P I G  G+  P  PP 
Sbjct: 243 DPLRPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPG 302

Query: 137 PKAAPLLYPPFPQVP-VVLQPAPSALFPP------------------------PAQLYPA 171
           P   P   P  P  P     P    L  P                        P +  P 
Sbjct: 303 P-PGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPG 361

Query: 172 APTPPALFSPPAGAAFPFPVYNGPMAGVPGP 202
            P PP     P       PV +    G PGP
Sbjct: 362 PPGPPGTAGLPGELGRVGPVGDPGRRGPPGP 392



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 32/115 (27%), Positives = 39/115 (33%), Gaps = 8/115 (6%)

Query: 24  PPSRTPP-QTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDP 82
           PP R P  Q +K +        F A M       D+   G P  P  P  P  P     P
Sbjct: 752 PPGRAPTDQHIKQVCMRVIQEHF-AEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFP 810

Query: 83  QMPAQPALPQLPRRPRTL------DEDGAAGEAGPVSKAAAGGAPHIGFVGEPPP 131
                  LP +   P  L       + G  GE GP  +   G    IG  G+P P
Sbjct: 811 GQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGP 865



 Score = 30.4 bits (67), Expect = 1.9
 Identities = 31/118 (26%), Positives = 35/118 (29%), Gaps = 27/118 (22%)

Query: 39  GEPGPPFPAGMPGGGSGSDTKG-GGSPATPEDP--------------RSPAKPAAPEDPQ 83
           G PGPP P G PG        G  G P     P              +    P       
Sbjct: 793 GRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNG 852

Query: 84  MPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAP 141
           +P    LP  P  P +   +G  GE GP   A   G P            PP P   P
Sbjct: 853 LPGAIGLPGDP-GPASYGRNGRDGERGPPGVAGIPGVP-----------GPPGPPGLP 898


>gi|18959210 WIRE protein [Homo sapiens]
          Length = 440

 Score = 58.2 bits (139), Expect = 8e-09
 Identities = 56/192 (29%), Positives = 65/192 (33%), Gaps = 18/192 (9%)

Query: 19  PLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAA 78
           PLP  P  R  P        G P PP P   P       T   G    P  P     P  
Sbjct: 208 PLPPTPGQRLHPGR-----EGPPAPP-PVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGV 261

Query: 79  PEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYA--PPD 136
           P  P  P   + P+LP+R  +L         G         +P +     PPP A  PP 
Sbjct: 262 PNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSL-LSNRPPPPARDPPS 320

Query: 137 PKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGPM 196
             AAP   PP P  PV+   A  A  PPP      +  P     PP  +  P     GP 
Sbjct: 321 RGAAP---PPPP--PVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTP----AGPP 371

Query: 197 AGVPGPATVEHR 208
              P P    HR
Sbjct: 372 PPPPPPLRNGHR 383



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 41/148 (27%), Positives = 57/148 (38%), Gaps = 27/148 (18%)

Query: 70  PRSPAKPAA--PEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVG 127
           PR P   A+  P+D    ++ +LP+LPR  R      +  +    +  ++ G  H     
Sbjct: 123 PRPPVSAASGRPQDDTDSSRASLPELPRMQRP-----SLPDLSRPNTTSSTGMKHSSSAP 177

Query: 128 EPPP-----YAPPDP-----KAAPLLYPPFPQVPVVLQ---------PAPSALFPPPAQL 168
            PPP      APP P       AP      P  P   Q         PAP  + PPP+ +
Sbjct: 178 PPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPAPPPVKPPPSPV 237

Query: 169 -YPAAPTPPALFSPPAGAAFPFPVYNGP 195
                P+  +L  PP     P  V NGP
Sbjct: 238 NIRTGPSGQSLAPPPPPYRQPPGVPNGP 265


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 61/165 (36%), Positives = 68/165 (41%), Gaps = 27/165 (16%)

Query: 28  TPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQ 87
           TPP TL  L +G      PAG      G   +G GS A    PR P K  +   P +P  
Sbjct: 94  TPP-TLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAP--SPRLPNKTIS--GPLIP-- 146

Query: 88  PALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPP-----DPKAAPL 142
              P  PR   T +  GAA  A P     A   P       PPP  PP      P   PL
Sbjct: 147 ---PASPRLGNTSEAHGAARTAPPRPNVPAPPPPT---PPPPPPPLPPPLPSSSPIKTPL 200

Query: 143 LYPPFP----QVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPA 183
           + PP P     +PVV  P P A  PPP    P  PTPP L  PPA
Sbjct: 201 VSPPGPLTKGNLPVVAPPVPCAPPPPPP---PPPPTPPPL--PPA 240



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 61/215 (28%), Positives = 74/215 (34%), Gaps = 48/215 (22%)

Query: 19  PLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAA 78
           P   AP  R P +T+        GP  P   P  G+ S+  G    A P  P  PA P  
Sbjct: 126 PGSRAPSPRLPNKTIS-------GPLIPPASPRLGNTSEAHGAARTAPPR-PNVPAPP-- 175

Query: 79  PEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGG-APHIGFVGEPPPYAPPD- 136
           P  P  P  P  P LP       +       GP++K      AP +     PPP  PP  
Sbjct: 176 PPTPPPPPPPLPPPLPSSSPI--KTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPT 233

Query: 137 ----------------PKAAPL----LYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPP 176
                           P+ APL    + PP P +P    P   A    PAQ     P PP
Sbjct: 234 PPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPP 293

Query: 177 ALFSPPAGAAFPFPVYNGPMAGVPGPATVEHRPLP 211
               P A  +        P A +P P      PLP
Sbjct: 294 PPLPPYASCS--------PRASLPAP------PLP 314



 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 61/216 (28%), Positives = 70/216 (32%), Gaps = 55/216 (25%)

Query: 1   MGRTSPICKQLREMLERWPLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGS------ 54
           +G TS      R    R  +PA PP   PP          P PP P  +P          
Sbjct: 152 LGNTSEAHGAARTAPPRPNVPAPPPPTPPP----------PPPPLPPPLPSSSPIKTPLV 201

Query: 55  ---GSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPA-----------------LPQLP 94
              G  TKG      P  P +P  P  P  P  P  P                  LP +P
Sbjct: 202 SPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIP 261

Query: 95  RRPRTLDEDGAAG-EAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAP---LLYPPFP-- 148
                L   G  G +A P S A     P       PPP  PP    +P   L  PP P  
Sbjct: 262 PPLPLLPPCGYPGLKAEPASPAQDAQEPPA-----PPPPLPPYASCSPRASLPAPPLPGV 316

Query: 149 ----QVPVVLQPAPSALFPPP----AQLYPAAPTPP 176
               + P  L P   +   PP    AQ  PA P PP
Sbjct: 317 NSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPP 352



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 45/163 (27%), Positives = 58/163 (35%), Gaps = 17/163 (10%)

Query: 55  GSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSK 114
           G++ +GGGS  T    R  + P    D      P L    +R    D  G     GP S+
Sbjct: 78  GTNKEGGGSANT----RGASTPPTLGDLFAGGFPVLRPAGQR----DVAGGKTGQGPGSR 129

Query: 115 AAAGGAPHIGFVGEPPPYAPP------DPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQL 168
           A +   P+    G   P A P      +   A    PP P VP    P P    PPP  L
Sbjct: 130 APSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPP---PPPPPL 186

Query: 169 YPAAPTPPALFSPPAGAAFPFPVYNGPMAGVPGPATVEHRPLP 211
            P  P+   + +P      P    N P+   P P      P P
Sbjct: 187 PPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPP 229



 Score = 37.0 bits (84), Expect = 0.020
 Identities = 34/115 (29%), Positives = 42/115 (36%), Gaps = 23/115 (20%)

Query: 21  PAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPE 80
           P APP   PP       +  P PP    +PG  S S+T        P  P+SP+  A P+
Sbjct: 289 PPAPPPPLPPYASCSPRASLPAPP----LPGVNSSSET------PPPLPPKSPSFQAPPQ 338

Query: 81  DPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPP 135
                A PA P  P              + P  +    G P  G     PP APP
Sbjct: 339 KAGAQALPAPPAPP-------------GSQPFLQKKRHGRPGAGGGKLNPPPAPP 380


>gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 56/205 (27%), Positives = 68/205 (33%), Gaps = 35/205 (17%)

Query: 20  LPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAP 79
           +P AP  + PP        G  GPP P G+PG G    T   G       P +P +P  P
Sbjct: 247 MPGAPGVKGPP--------GMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPG-P 297

Query: 80  EDP---------------QMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIG 124
           + P                 P Q  +P  P  P    E G  G  GP       G P IG
Sbjct: 298 QGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPP------GLPGIG 351

Query: 125 FVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAG 184
             G P P         P    P  +   +  P       PP +  P  P  P    PP  
Sbjct: 352 KPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGG---PPGE--PGLPGIPGPMGPPGA 406

Query: 185 AAFPFPVYNGPMAGVPGPATVEHRP 209
             FP P   G + G  GP   +  P
Sbjct: 407 IGFPGPKGEGGIVGPQGPPGPKGEP 431



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 52/173 (30%), Positives = 60/173 (34%), Gaps = 17/173 (9%)

Query: 39  GEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPR 98
           GEPGP  P G+PG        G G P     P  P  P    +  +P  P  P LP    
Sbjct: 293 GEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLP---- 348

Query: 99  TLDEDGAAGEAGPVSKAAAGGAP-HIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPA 157
                G  G  GP      GG P  +G  GE  P   P     P   P  P +P  + P 
Sbjct: 349 ---GIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPG-IGGPPGEPGLPGIPGPMGPP 404

Query: 158 PSALFPPP--------AQLYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVPGP 202
            +  FP P         Q  P     P L   P    F   V    M G+PGP
Sbjct: 405 GAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGP 457



 Score = 51.6 bits (122), Expect = 8e-07
 Identities = 53/177 (29%), Positives = 61/177 (34%), Gaps = 17/177 (9%)

Query: 37  PSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMP--AQPALPQLP 94
           P G PG   P G+PG G        G P  P        P  P  P +P   +P  P  P
Sbjct: 300 PIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPG-P 358

Query: 95  RRPRTL----DEDGAAGEAGPVSKAAAGGAP-HIGFVGEPPPYAPPDPKAAPLLYPPFPQ 149
           +  R +       G  GE GP+     GG P   G  G P P  PP     P   P    
Sbjct: 359 KGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFP--GPKGEG 416

Query: 150 VPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGP-----MAGVPG 201
             V  Q  P     P  Q +P  P       PP     P P+  GP       GVPG
Sbjct: 417 GIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPI--GPKGEAGQKGVPG 471



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 53/177 (29%), Positives = 62/177 (35%), Gaps = 34/177 (19%)

Query: 37  PSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRR 96
           P GEPG P   G+ G        G G P+ P  P  P  P    +P +P  P  P + + 
Sbjct: 481 PKGEPGIPGDQGLQGPPG---IPGIGGPSGPIGP--PGIPGPKGEPGLPGPPGFPGIGK- 534

Query: 97  PRTLDEDGAAGEAGPVSKAAA-GGAPHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQ 155
                  G AG  GP  K  A G     G  G P P  PP P   P + PP P       
Sbjct: 535 ------PGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGP---PAVMPPTPPPQGEYL 585

Query: 156 P----APSALFPP------------PAQLYPAAPTPPALFSPPAGAAFPFP--VYNG 194
           P        + PP            PA   PA         PP GA   F   +YNG
Sbjct: 586 PDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNG 642



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 50/180 (27%), Positives = 62/180 (34%), Gaps = 27/180 (15%)

Query: 21  PAAPPSRTPPQTLKHLPS-----GEPGPPFPAGMPG--GGSGSDTKGG--GSPATPEDPR 71
           P  PP       L+  P      GE GPP   G+PG  G  G   + G  G P  P    
Sbjct: 421 PQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG 480

Query: 72  SPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPP 131
              +P  P D  +   P +P +      +   G  G  G        G P IG  G    
Sbjct: 481 PKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGL 540

Query: 132 YAPP------DPKAAP-LLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAG 184
           + PP       P+  P L  PP P  P    P P A+ PP        P P   + P  G
Sbjct: 541 HGPPGKPGALGPQGQPGLPGPPGPPGP----PGPPAVMPP-------TPPPQGEYLPDMG 589



 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 62/227 (27%), Positives = 73/227 (32%), Gaps = 51/227 (22%)

Query: 19  PLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAA 78
           P P  PP   PP    H   G  G P P G PG G        G P  P  P +   P A
Sbjct: 126 PGPRGPPG--PPGLPGHGIPGIKGKPGPQGYPGVGKP------GMPGMPGKPGAMGMPGA 177

Query: 79  -----------------PEDPQMP------AQPALPQLPRRPRTLDEDGAAGEAGPVSKA 115
                            P+ P  P       +P  P LP +P    + G  G  GP    
Sbjct: 178 KGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLR 237

Query: 116 AAGGAPHIGFVGEP----PP--YAPPDPKAAP------LLYPPFPQVPVVLQPAPSALFP 163
              G    G  G P    PP  + PP P   P      +   P PQ P+    AP    P
Sbjct: 238 GPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGP 297

Query: 164 PPAQLYPAAPTPPAL--FSPPAGAAFP----FPVYNGP--MAGVPGP 202
                 P    PP +     P     P    FP   G   + G+PGP
Sbjct: 298 QGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGP 344



 Score = 45.1 bits (105), Expect = 7e-05
 Identities = 63/273 (23%), Positives = 81/273 (29%), Gaps = 99/273 (36%)

Query: 19  PLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSD--------------------- 57
           PLP   P + PPQ  ++ P G+  P  P    G   G +                     
Sbjct: 35  PLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQ 94

Query: 58  ---------------------TKGGGSPATPEDPRSPAKP--------------AAPEDP 82
                                 +G   P     PR P  P                P+  
Sbjct: 95  PAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGY 154

Query: 83  QMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAP- 141
               +P +P +P +P  +   GA GE G   +        IG +G P P  PP P   P 
Sbjct: 155 PGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGE--------IGPMGIPGPQGPPGPHGLPG 206

Query: 142 LLYPPFPQVPVVLQPAPSA-----LFPPPAQL----------YPAAP---TPPALFSPPA 183
           +  P  P +P   QP P         P P  L           P AP    PP +  PP 
Sbjct: 207 IGKPGGPGLPG--QPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPG 264

Query: 184 GAAFP---------FPVYNGPMA-----GVPGP 202
               P         FP   GP+      G PGP
Sbjct: 265 PVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGP 297


>gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 56/205 (27%), Positives = 68/205 (33%), Gaps = 35/205 (17%)

Query: 20  LPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAP 79
           +P AP  + PP        G  GPP P G+PG G    T   G       P +P +P  P
Sbjct: 247 MPGAPGVKGPP--------GMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPG-P 297

Query: 80  EDP---------------QMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIG 124
           + P                 P Q  +P  P  P    E G  G  GP       G P IG
Sbjct: 298 QGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPP------GLPGIG 351

Query: 125 FVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAG 184
             G P P         P    P  +   +  P       PP +  P  P  P    PP  
Sbjct: 352 KPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGG---PPGE--PGLPGIPGPMGPPGA 406

Query: 185 AAFPFPVYNGPMAGVPGPATVEHRP 209
             FP P   G + G  GP   +  P
Sbjct: 407 IGFPGPKGEGGIVGPQGPPGPKGEP 431



 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 52/173 (30%), Positives = 60/173 (34%), Gaps = 17/173 (9%)

Query: 39  GEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRRPR 98
           GEPGP  P G+PG        G G P     P  P  P    +  +P  P  P LP    
Sbjct: 293 GEPGPQGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLP---- 348

Query: 99  TLDEDGAAGEAGPVSKAAAGGAP-HIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQPA 157
                G  G  GP      GG P  +G  GE  P   P     P   P  P +P  + P 
Sbjct: 349 ---GIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPG-IGGPPGEPGLPGIPGPMGPP 404

Query: 158 PSALFPPP--------AQLYPAAPTPPALFSPPAGAAFPFPVYNGPMAGVPGP 202
            +  FP P         Q  P     P L   P    F   V    M G+PGP
Sbjct: 405 GAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGP 457



 Score = 51.6 bits (122), Expect = 8e-07
 Identities = 53/177 (29%), Positives = 61/177 (34%), Gaps = 17/177 (9%)

Query: 37  PSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMP--AQPALPQLP 94
           P G PG   P G+PG G        G P  P        P  P  P +P   +P  P  P
Sbjct: 300 PIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPG-P 358

Query: 95  RRPRTL----DEDGAAGEAGPVSKAAAGGAP-HIGFVGEPPPYAPPDPKAAPLLYPPFPQ 149
           +  R +       G  GE GP+     GG P   G  G P P  PP     P   P    
Sbjct: 359 KGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFP--GPKGEG 416

Query: 150 VPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAGAAFPFPVYNGP-----MAGVPG 201
             V  Q  P     P  Q +P  P       PP     P P+  GP       GVPG
Sbjct: 417 GIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPI--GPKGEAGQKGVPG 471



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 53/177 (29%), Positives = 62/177 (35%), Gaps = 34/177 (19%)

Query: 37  PSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAAPEDPQMPAQPALPQLPRR 96
           P GEPG P   G+ G        G G P+ P  P  P  P    +P +P  P  P + + 
Sbjct: 481 PKGEPGIPGDQGLQGPPG---IPGIGGPSGPIGP--PGIPGPKGEPGLPGPPGFPGIGK- 534

Query: 97  PRTLDEDGAAGEAGPVSKAAA-GGAPHIGFVGEPPPYAPPDPKAAPLLYPPFPQVPVVLQ 155
                  G AG  GP  K  A G     G  G P P  PP P   P + PP P       
Sbjct: 535 ------PGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGP---PAVMPPTPPPQGEYL 585

Query: 156 P----APSALFPP------------PAQLYPAAPTPPALFSPPAGAAFPFP--VYNG 194
           P        + PP            PA   PA         PP GA   F   +YNG
Sbjct: 586 PDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNG 642



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 50/180 (27%), Positives = 62/180 (34%), Gaps = 27/180 (15%)

Query: 21  PAAPPSRTPPQTLKHLPS-----GEPGPPFPAGMPG--GGSGSDTKGG--GSPATPEDPR 71
           P  PP       L+  P      GE GPP   G+PG  G  G   + G  G P  P    
Sbjct: 421 PQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLG 480

Query: 72  SPAKPAAPEDPQMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPP 131
              +P  P D  +   P +P +      +   G  G  G        G P IG  G    
Sbjct: 481 PKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGL 540

Query: 132 YAPP------DPKAAP-LLYPPFPQVPVVLQPAPSALFPPPAQLYPAAPTPPALFSPPAG 184
           + PP       P+  P L  PP P  P    P P A+ PP        P P   + P  G
Sbjct: 541 HGPPGKPGALGPQGQPGLPGPPGPPGP----PGPPAVMPP-------TPPPQGEYLPDMG 589



 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 62/227 (27%), Positives = 73/227 (32%), Gaps = 51/227 (22%)

Query: 19  PLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSDTKGGGSPATPEDPRSPAKPAA 78
           P P  PP   PP    H   G  G P P G PG G        G P  P  P +   P A
Sbjct: 126 PGPRGPPG--PPGLPGHGIPGIKGKPGPQGYPGVGKP------GMPGMPGKPGAMGMPGA 177

Query: 79  -----------------PEDPQMP------AQPALPQLPRRPRTLDEDGAAGEAGPVSKA 115
                            P+ P  P       +P  P LP +P    + G  G  GP    
Sbjct: 178 KGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLR 237

Query: 116 AAGGAPHIGFVGEP----PP--YAPPDPKAAP------LLYPPFPQVPVVLQPAPSALFP 163
              G    G  G P    PP  + PP P   P      +   P PQ P+    AP    P
Sbjct: 238 GPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGP 297

Query: 164 PPAQLYPAAPTPPAL--FSPPAGAAFP----FPVYNGP--MAGVPGP 202
                 P    PP +     P     P    FP   G   + G+PGP
Sbjct: 298 QGPIGVPGVQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGP 344



 Score = 45.1 bits (105), Expect = 7e-05
 Identities = 63/273 (23%), Positives = 81/273 (29%), Gaps = 99/273 (36%)

Query: 19  PLPAAPPSRTPPQTLKHLPSGEPGPPFPAGMPGGGSGSD--------------------- 57
           PLP   P + PPQ  ++ P G+  P  P    G   G +                     
Sbjct: 35  PLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPHLPQYMKEIQ 94

Query: 58  ---------------------TKGGGSPATPEDPRSPAKP--------------AAPEDP 82
                                 +G   P     PR P  P                P+  
Sbjct: 95  PAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGY 154

Query: 83  QMPAQPALPQLPRRPRTLDEDGAAGEAGPVSKAAAGGAPHIGFVGEPPPYAPPDPKAAP- 141
               +P +P +P +P  +   GA GE G   +        IG +G P P  PP P   P 
Sbjct: 155 PGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGE--------IGPMGIPGPQGPPGPHGLPG 206

Query: 142 LLYPPFPQVPVVLQPAPSA-----LFPPPAQL----------YPAAP---TPPALFSPPA 183
           +  P  P +P   QP P         P P  L           P AP    PP +  PP 
Sbjct: 207 IGKPGGPGLPG--QPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPG 264

Query: 184 GAAFP---------FPVYNGPMA-----GVPGP 202
               P         FP   GP+      G PGP
Sbjct: 265 PVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGP 297


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.138    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,548,626
Number of Sequences: 37866
Number of extensions: 1448982
Number of successful extensions: 31421
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 700
Number of HSP's successfully gapped in prelim test: 1738
Number of HSP's that attempted gapping in prelim test: 10577
Number of HSP's gapped (non-prelim): 10858
length of query: 288
length of database: 18,247,518
effective HSP length: 101
effective length of query: 187
effective length of database: 14,423,052
effective search space: 2697110724
effective search space used: 2697110724
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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