Guide to the Human Genome
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Search of human proteins with 20143962

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20143962 distal-less homeobox 4 isoform a [Homo sapiens]
         (240 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20143962 distal-less homeobox 4 isoform a [Homo sapiens]           499   e-142
gi|20143960 distal-less homeobox 4 isoform b [Homo sapiens]           305   2e-83
gi|82659115 distal-less homeobox 6 [Homo sapiens]                     161   4e-40
gi|64225290 distal-less homeobox 1 isoform 1 [Homo sapiens]           156   2e-38
gi|4885185 distal-less homeobox 3 [Homo sapiens]                      124   7e-29
gi|4758168 distal-less homeobox 2 [Homo sapiens]                      122   2e-28
gi|4885187 distal-less homeobox 5 [Homo sapiens]                      117   7e-27
gi|118582284 msh homeobox 1 [Homo sapiens]                             89   3e-18
gi|6633798 BarH-like homeobox 2 [Homo sapiens]                         87   2e-17
gi|121114296 caudal type homeobox 1 [Homo sapiens]                     80   2e-15
gi|153218470 BarH-like homeobox 1 [Homo sapiens]                       79   3e-15
gi|27886557 msh homeobox 2 [Homo sapiens]                              78   6e-15
gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens]    77   1e-14
gi|148746211 NK2 transcription factor related, locus 3 [Homo sap...    77   1e-14
gi|147901462 brain specific homeobox [Homo sapiens]                    76   2e-14
gi|210147470 NK2 transcription factor related, locus 6 [Homo sap...    75   5e-14
gi|19923352 NK3 homeobox 1 [Homo sapiens]                              74   9e-14
gi|226437602 NK1 homeobox 2 [Homo sapiens]                             74   1e-13
gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  74   1e-13
gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  74   1e-13
gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]                  74   1e-13
gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  74   1e-13
gi|31377777 NK2 homeobox 8 [Homo sapiens]                              74   1e-13
gi|4502365 NK3 homeobox 2 [Homo sapiens]                               74   1e-13
gi|24497513 homeobox A3 isoform a [Homo sapiens]                       73   3e-13
gi|13562112 homeobox A3 isoform a [Homo sapiens]                       73   3e-13
gi|89257348 homeo box HB9 [Homo sapiens]                               72   4e-13
gi|7710121 engrailed homeobox 2 [Homo sapiens]                         71   7e-13
gi|70608170 H6 family homeobox 2 [Homo sapiens]                        70   1e-12
gi|39930383 BarH-like homeobox 2 [Homo sapiens]                        70   1e-12

>gi|20143962 distal-less homeobox 4 isoform a [Homo sapiens]
          Length = 240

 Score =  499 bits (1285), Expect = e-142
 Identities = 240/240 (100%), Positives = 240/240 (100%)

Query: 1   MTSLPCPLPGRDASKAVFPDLAPVPSVAAAYPLGLSPTTAASPNLSYSRPYGHLLSYPYT 60
           MTSLPCPLPGRDASKAVFPDLAPVPSVAAAYPLGLSPTTAASPNLSYSRPYGHLLSYPYT
Sbjct: 1   MTSLPCPLPGRDASKAVFPDLAPVPSVAAAYPLGLSPTTAASPNLSYSRPYGHLLSYPYT 60

Query: 61  EPANPGDSYLSCQQPAALSQPLCGPAEHPQELEADSEKPRLSPEPSERRPQAPAKKLRKP 120
           EPANPGDSYLSCQQPAALSQPLCGPAEHPQELEADSEKPRLSPEPSERRPQAPAKKLRKP
Sbjct: 61  EPANPGDSYLSCQQPAALSQPLCGPAEHPQELEADSEKPRLSPEPSERRPQAPAKKLRKP 120

Query: 121 RTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQNS 180
           RTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQNS
Sbjct: 121 RTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQNS 180

Query: 181 GGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGTLPTSGYGNSFGAWYQHHSSDVLASPQMM 240
           GGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGTLPTSGYGNSFGAWYQHHSSDVLASPQMM
Sbjct: 181 GGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGTLPTSGYGNSFGAWYQHHSSDVLASPQMM 240


>gi|20143960 distal-less homeobox 4 isoform b [Homo sapiens]
          Length = 168

 Score =  305 bits (781), Expect = 2e-83
 Identities = 154/174 (88%), Positives = 155/174 (89%), Gaps = 11/174 (6%)

Query: 70  LSCQQPAALSQP---LCGPAEHPQELEADSEKPRLSPEPSERRPQAPAKKLRKPRTIYSS 126
           LS   P +L  P   LC P         DSEKPRLSPEPSERRPQAPAKKLRKPRTIYSS
Sbjct: 3   LSVLPPRSLLAPYTVLCCPP--------DSEKPRLSPEPSERRPQAPAKKLRKPRTIYSS 54

Query: 127 LQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQNSGGQEGD 186
           LQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQNSGGQEGD
Sbjct: 55  LQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQNSGGQEGD 114

Query: 187 FPGRTFSVSPCSPPLPSLWDLPKAGTLPTSGYGNSFGAWYQHHSSDVLASPQMM 240
           FPGRTFSVSPCSPPLPSLWDLPKAGTLPTSGYGNSFGAWYQHHSSDVLASPQMM
Sbjct: 115 FPGRTFSVSPCSPPLPSLWDLPKAGTLPTSGYGNSFGAWYQHHSSDVLASPQMM 168


>gi|82659115 distal-less homeobox 6 [Homo sapiens]
          Length = 265

 Score =  161 bits (408), Expect = 4e-40
 Identities = 106/262 (40%), Positives = 139/262 (53%), Gaps = 22/262 (8%)

Query: 1   MTSLPCPLPGRDASKAVFPDLAPV------PSVAAA-YPLGLSPTTAASPNLS------- 46
           MT++   L G+D+SK+ F +          P++A A YPL    + AA+           
Sbjct: 4   MTTMADGLEGQDSSKSAFMEFGQQQQQQHSPAMAGAHYPLHCLHSAAAAAAAGSHHHHHH 63

Query: 47  ----YSRPYGHLLSYPYTEPANPGDSYLSCQQPAALSQPLCGPAEHPQELEADSEKPRLS 102
               +  PY       Y   +     Y+S  Q +   Q     +   Q    D+++ + +
Sbjct: 64  QHHHHGSPYASGGGNSYNHRSLAAYPYMSHSQHSPYLQSYHNSSAAAQTRGDDTDQQKTT 123

Query: 103 P-EPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQV 161
             E  E R     KK+RKPRTIYSSLQLQ LN RFQ TQYLALPERA+LAA LGLTQTQV
Sbjct: 124 VIENGEIRFNGKGKKIRKPRTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQV 183

Query: 162 KIWFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVSPCSPPLPSLWDL---PKAGTLPTSGY 218
           KIWFQNKRSK+KKLLKQ S   E D    + ++SP SP LP +WD+    K  ++P + Y
Sbjct: 184 KIWFQNKRSKFKKLLKQGSNPHESDPLQGSAALSPRSPALPPVWDVSASAKGVSMPPNSY 243

Query: 219 GNSFGAWYQHHSSDVLASPQMM 240
              +  WY     D +  PQMM
Sbjct: 244 MPGYSHWYSSPHQDTMQRPQMM 265


>gi|64225290 distal-less homeobox 1 isoform 1 [Homo sapiens]
          Length = 255

 Score =  156 bits (394), Expect = 2e-38
 Identities = 109/261 (41%), Positives = 137/261 (52%), Gaps = 29/261 (11%)

Query: 1   MTSLPCPLPGRDASKAVFPDLAPVPSVAAAYPLG--------------LSPTTAASPNLS 46
           MT++P  L    + KAVF +  P     +  P+                 P  A S   S
Sbjct: 3   MTTMPESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSASS 62

Query: 47  YSRPYGHLLSYPYTEPANPGDS--YLSCQQPAALSQPLCGPAEHPQELEADSEKPRLSPE 104
           +SRP G    YPY    +   S  Y+S  Q    S  L       ++  ADSEK  +  E
Sbjct: 63  FSRPLG----YPYVNSVSSHASSPYISSVQSYPGSASLA--QSRLEDPGADSEKSTVV-E 115

Query: 105 PSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIW 164
             E R     KK+RKPRTIYSSLQLQ LN+RFQ TQYLALPERA+LAA LGLTQTQVKIW
Sbjct: 116 GGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIW 175

Query: 165 FQNKRSKYKKLLKQNSGGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGTLPTSG-----YG 219
           FQNKRSK+KKL+KQ     EG       ++S  SPP+P  W+ P + +   SG     Y 
Sbjct: 176 FQNKRSKFKKLMKQGGAALEGSALANGRALSAGSPPVPPGWN-PNSSSGKGSGGNAGSYI 234

Query: 220 NSFGAWYQHHSSDVLASPQMM 240
            S+ +WY     + +  PQ+M
Sbjct: 235 PSYTSWYPSAHQEAMQQPQLM 255


>gi|4885185 distal-less homeobox 3 [Homo sapiens]
          Length = 287

 Score =  124 bits (311), Expect = 7e-29
 Identities = 83/179 (46%), Positives = 98/179 (54%), Gaps = 28/179 (15%)

Query: 34  GLSPTTAASPNLSYSRPYGHLLSYPYTEPANPGDSYLSCQQPAALSQPLCGPAEHPQELE 93
           GL+ T A SP   Y+                 G SY   Q  A   QPL  PA+ P  ++
Sbjct: 73  GLAGTGAYSPKSEYTY----------------GASYR--QYGAYREQPL--PAQDPVSVK 112

Query: 94  ADSEKPRLSPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQ 153
            +       PE   R      KK+RKPRTIYSS QL  L +RFQ  QYLALPERA+LAAQ
Sbjct: 113 EE-------PEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQ 165

Query: 154 LGLTQTQVKIWFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGT 212
           LGLTQTQVKIWFQN+RSK+KKL K      E   P  + S++  SPP P+LWD     T
Sbjct: 166 LGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHS-PNNSDSMACNSPPSPALWDTSSHST 223


>gi|4758168 distal-less homeobox 2 [Homo sapiens]
          Length = 328

 Score =  122 bits (307), Expect = 2e-28
 Identities = 78/165 (47%), Positives = 93/165 (56%), Gaps = 13/165 (7%)

Query: 50  PYGHLLSYPYTE------PANPGDSYLSCQQPAALSQPLCGPAEHPQELEADSEKPRLSP 103
           PY H+ SY Y        P +   SY      A  S    G +  P    A++E  +   
Sbjct: 83  PYAHMGSYQYQASGLNNVPYSAKSSYDLGYTAAYTSYAPYGTSSSP----ANNEPEKEDL 138

Query: 104 EPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKI 163
           EP  R      KK+RKPRTIYSS QL  L +RFQ TQYLALPERA+LAA LGLTQTQVKI
Sbjct: 139 EPEIRIVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKI 198

Query: 164 WFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVSPCSPPL--PSLWD 206
           WFQN+RSK+KK+ K      E   PG + S    SPP+  P+ WD
Sbjct: 199 WFQNRRSKFKKMWKSGEIPSE-QHPGASASPPCASPPVSAPASWD 242


>gi|4885187 distal-less homeobox 5 [Homo sapiens]
          Length = 289

 Score =  117 bits (294), Expect = 7e-27
 Identities = 67/145 (46%), Positives = 83/145 (57%), Gaps = 16/145 (11%)

Query: 104 EPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKI 163
           EP  R      KK+RKPRTIYSS QL  L +RFQ TQYLALPERA+LAA LGLTQTQVKI
Sbjct: 124 EPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKI 183

Query: 164 WFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVSPCSPPLPSLWD---------------LP 208
           WFQNKRSK KK++K      E   P  +  ++  SP  P++W+                P
Sbjct: 184 WFQNKRSKIKKIMKNGEMPPEHS-PSSSDPMACNSPQSPAVWEPQGSSRSLSHHPHAHPP 242

Query: 209 KAGTLPTSGYGNSFGAWYQHHSSDV 233
            +   P S Y  +  +WY   +S +
Sbjct: 243 TSNQSPASSYLENSASWYTSAASSI 267


>gi|118582284 msh homeobox 1 [Homo sapiens]
          Length = 303

 Score = 89.0 bits (219), Expect = 3e-18
 Identities = 70/204 (34%), Positives = 96/204 (47%), Gaps = 37/204 (18%)

Query: 21  LAPVPSVAAA----YPLGLSPTTAASPNLSYS-RPYGHLLSYPYTEPANPGDSYLSCQQP 75
           LAP   V AA     PLG+ P +  +P+   S RP GH                 S    
Sbjct: 80  LAPSEGVQAAGGSAQPLGVPPGSLGAPDAPSSPRPLGHF----------------SVGGL 123

Query: 76  AALSQPLCGPAEHPQELEADS--EKPRLSPEPSERRPQAPA------KKLRKPRTIYSSL 127
             L +     AE P++ E     + PR SP P+ RR   PA      K  RKPRT +++ 
Sbjct: 124 LKLPEDALVKAESPEKPERTPWMQSPRFSPPPA-RRLSPPACTLRKHKTNRKPRTPFTTA 182

Query: 128 QLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQNSGGQEGDF 187
           QL  L ++F+  QYL++ ERA+ ++ L LT+TQVKIWFQN+R+K K+L       QE + 
Sbjct: 183 QLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRL-------QEAEL 235

Query: 188 PGRTFSVSPCSPPLPSLWDLPKAG 211
                +  P  PP       P  G
Sbjct: 236 EKLKMAAKPMLPPAAFGLSFPLGG 259


>gi|6633798 BarH-like homeobox 2 [Homo sapiens]
          Length = 279

 Score = 86.7 bits (213), Expect = 2e-17
 Identities = 65/182 (35%), Positives = 95/182 (52%), Gaps = 31/182 (17%)

Query: 36  SPTTAASPNLSYSRPYGHLLSYPYTEPANPGDSY-LSCQQPAALSQPLCGPAEHPQELEA 94
           SP+  A P LS       ++S+    PA PG +  LSC Q   +++ +   A   + L A
Sbjct: 64  SPSLRAYPLLSVITRQPTVISH--LVPATPGIAQALSCHQ---VTEAVSAEAPGGEAL-A 117

Query: 95  DSEKPRLSPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQL 154
            SE     P P +++P       R+ RTI++ LQL  L ++FQ  +YL+ P+R  LA  L
Sbjct: 118 SSESETEQPTPRQKKP-------RRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSL 170

Query: 155 GLTQTQVKIWFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGTLP 214
           GLTQ QVK W+QN+R K+KK++ +  GGQE          +P  P        PK  ++P
Sbjct: 171 GLTQLQVKTWYQNRRMKWKKMVLK--GGQE----------APTKPK-----GRPKKNSIP 213

Query: 215 TS 216
           TS
Sbjct: 214 TS 215


>gi|121114296 caudal type homeobox 1 [Homo sapiens]
          Length = 265

 Score = 79.7 bits (195), Expect = 2e-15
 Identities = 67/212 (31%), Positives = 96/212 (45%), Gaps = 20/212 (9%)

Query: 5   PCPLPGRDASKAVFPDLAPVPSVAAAYPLGLSPTTAASPNLSYSRPYGHLLSYPYTEPAN 64
           P P P   A  A FP  AP    AAAY  G +   A+  +L++  P       P   P  
Sbjct: 53  PAPAPPT-AWGAPFP--APKDDWAAAYGPGPAAPAASPASLAFGPPPDFS---PVPAPPG 106

Query: 65  PGDSYLSCQQPAALSQPLCGPAEHPQELEADSEKP----RLSPEPSERRPQAPAKKLRKP 120
           PG        P  L+QPL GP   P    A    P    R S            +   K 
Sbjct: 107 PG--------PGLLAQPLGGPGT-PSSPGAQRPTPYEWMRRSVAAGGGGGSGKTRTKDKY 157

Query: 121 RTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQNS 180
           R +Y+  Q   L + F +++Y+ +  +++LAA LGLT+ QVKIWFQN+R+K +K+ K+  
Sbjct: 158 RVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAKERKVNKKKQ 217

Query: 181 GGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGT 212
             Q+   P     ++  +P  PSL  L  + T
Sbjct: 218 QQQQPPQPPMAHDIT-ATPAGPSLGGLCPSNT 248


>gi|153218470 BarH-like homeobox 1 [Homo sapiens]
          Length = 254

 Score = 79.0 bits (193), Expect = 3e-15
 Identities = 69/201 (34%), Positives = 94/201 (46%), Gaps = 26/201 (12%)

Query: 22  APVPSVAAAYPL---GLSPTTAASPNLSYSRPYGHLLSYPYTEPANP-GDSYLSCQQPAA 77
           AP  + AAA  L   G+    AA P  S+        +  +  P  P G S LS    AA
Sbjct: 45  APAAAAAAAGELLKFGVQALLAARPFHSHLAVLKAEQAAVFKFPLAPLGCSGLSSALLAA 104

Query: 78  -LSQPLCGPAEH-PQELEADSEKPRLSPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQR 135
               P    A H P EL+   +     P      P   AKK R+ RT+++ LQL  L +R
Sbjct: 105 GPGLPGAAGAPHLPLELQLRGKLEAAGPG----EPGTKAKKGRRSRTVFTELQLMGLEKR 160

Query: 136 FQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVS 195
           F+  +YL+ P+R  LA  LGL+Q QVK W+QN+R K+KK++ Q  G +           S
Sbjct: 161 FEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKKIVLQGGGLE-----------S 209

Query: 196 PCSPPLPSLWDLPKAGTLPTS 216
           P  P        PK  ++PTS
Sbjct: 210 PTKPK-----GRPKKNSIPTS 225


>gi|27886557 msh homeobox 2 [Homo sapiens]
          Length = 267

 Score = 78.2 bits (191), Expect = 6e-15
 Identities = 51/137 (37%), Positives = 72/137 (52%), Gaps = 15/137 (10%)

Query: 97  EKPRLSPEPSERRPQAPA----KKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAA 152
           E  R SP P    P        K  RKPRT +++ QL  L ++F+  QYL++ ERA+ ++
Sbjct: 118 EPGRYSPPPRHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSS 177

Query: 153 QLGLTQTQVKIWFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGT 212
            L LT+TQVKIWFQN+R+K K+L       QE +      +  P    LPS + LP   +
Sbjct: 178 SLNLTETQVKIWFQNRRAKAKRL-------QEAELEKLKMAAKPM---LPSSFSLPFPIS 227

Query: 213 LPTSGYGNSFGAWYQHH 229
            P     + +GA Y  H
Sbjct: 228 SPLQA-ASIYGASYPFH 243


>gi|4758090 NK2 transcription factor related, locus 5 [Homo sapiens]
          Length = 324

 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 59/161 (36%), Positives = 84/161 (52%), Gaps = 13/161 (8%)

Query: 21  LAPVPSVAAAY-PLGLSPTTAASPNLSYSRPYGHLLSYPYTEPANPGDSYLSCQQ--PAA 77
           LAP   + AA+ P   +   AA+P L   R    L   P   PA    ++ +     P A
Sbjct: 41  LAPSSCMLAAFKPEAYAGPEAAAPGLPELR--AELGRAP--SPAKCASAFPAAPAFYPRA 96

Query: 78  LSQPLCGPAEHPQ----ELEADSEKPRLSPEPSERRPQAPAKKLRKPRTIYSSLQLQHLN 133
            S P   PA+ P+    EL A  +   L    ++   +  A++ RKPR ++S  Q+  L 
Sbjct: 97  YSDP--DPAKDPRAEKKELCALQKAVELEKTEADNAERPRARRRRKPRVLFSQAQVYELE 154

Query: 134 QRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKK 174
           +RF+  +YL+ PER QLA+ L LT TQVKIWFQN+R K K+
Sbjct: 155 RRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKCKR 195


>gi|148746211 NK2 transcription factor related, locus 3 [Homo
           sapiens]
          Length = 364

 Score = 77.4 bits (189), Expect = 1e-14
 Identities = 54/170 (31%), Positives = 77/170 (45%), Gaps = 30/170 (17%)

Query: 85  PAEHPQELEADSEKPRLSPE------------PSERRPQAPAKKLRKPRTIYSSLQLQHL 132
           P EH +E E   ++ + S +             +E   +   +  RKPR ++S  Q+  L
Sbjct: 104 PKEHEEEPEVVRDRSQKSCQLKKSLETAGDCKAAEESERPKPRSRRKPRVLFSQAQVFEL 163

Query: 133 NQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQNS---GGQEGDFPG 189
            +RF+  +YL+ PER  LA+ L LT TQVKIWFQN+R K K+  +  S   G      P 
Sbjct: 164 ERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGAHAPPPPP 223

Query: 190 RTFSV-------SPCSPPLPSLWDLPKA--------GTLPTSGYGNSFGA 224
           R  +V        PC  P    +  P +         + P  GYGNS  A
Sbjct: 224 RRVAVPVLVRDGKPCVTPSAQAYGAPYSVGASAYSYNSFPAYGYGNSAAA 273


>gi|147901462 brain specific homeobox [Homo sapiens]
          Length = 233

 Score = 76.3 bits (186), Expect = 2e-14
 Identities = 48/127 (37%), Positives = 66/127 (51%), Gaps = 6/127 (4%)

Query: 54  LLSYPYTEPANPGDSYLSCQQPAALSQPLCGPAEHPQELEADSEK-PRLSPEPSERRPQA 112
           LL Y Y  P  P  + L+      L +   G   HP  L       P L P P       
Sbjct: 51  LLDYGY--PLMPTPTLLAPHAHHPLHK---GDHHHPYFLTTSGMPVPALFPHPQHAELPG 105

Query: 113 PAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKY 172
              + RK RT++S  QL  L +RF+  +YL+ PER +LA  L L++TQVK WFQN+R K+
Sbjct: 106 KHCRRRKARTVFSDSQLSGLEKRFEIQRYLSTPERVELATALSLSETQVKTWFQNRRMKH 165

Query: 173 KKLLKQN 179
           KK L+++
Sbjct: 166 KKQLRKS 172


>gi|210147470 NK2 transcription factor related, locus 6 [Homo
           sapiens]
          Length = 219

 Score = 75.1 bits (183), Expect = 5e-14
 Identities = 50/130 (38%), Positives = 63/130 (48%), Gaps = 11/130 (8%)

Query: 108 RRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQN 167
           R  Q  A++ RKPR ++S  Q+  L +RF+  +YL+ PER  LA+ L LT TQVKIWFQN
Sbjct: 41  RSEQPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQN 100

Query: 168 KRSKYKKLLKQNSGGQEGD--------FPGRTFSVSPCSPPLPSLWDLP---KAGTLPTS 216
           +R K K+  +  S    G          P       PC  P P     P    A   P S
Sbjct: 101 RRYKCKRQRQDKSLELAGHPLTPRRVAVPVLVRDGKPCLGPGPGAPAFPSPYSAAVSPYS 160

Query: 217 GYGNSFGAWY 226
            YG   GA Y
Sbjct: 161 CYGGYSGAPY 170


>gi|19923352 NK3 homeobox 1 [Homo sapiens]
          Length = 234

 Score = 74.3 bits (181), Expect = 9e-14
 Identities = 61/180 (33%), Positives = 81/180 (45%), Gaps = 31/180 (17%)

Query: 23  PVPSVAAAYPLGLSPTTAASPNLSY----------SRPYGHLLSY------PYTEPANPG 66
           P P    A   G +P T + P  S+           R  G   S       P  EP   G
Sbjct: 5   PEPRPGEAKAEGAAPPTPSKPLTSFLIQDILRDGAQRQGGRTSSQRQRDPEPEPEPEPEG 64

Query: 67  DSYLSCQQPAALSQPLCGPAEHPQELE--ADSEKPR------LSPEPSE----RRPQAPA 114
               +  Q   LS    GP   P+E E  A++E  R      L  E +     R PQ P 
Sbjct: 65  GRSRAGAQNDQLST---GPRAAPEEAETLAETEPERHLGSYLLDSENTSGALPRLPQTPK 121

Query: 115 KKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKK 174
           +  ++ R  +S  Q+  L ++F H +YL+ PERA LA  L LT+TQVKIWFQN+R K K+
Sbjct: 122 QPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKR 181


>gi|226437602 NK1 homeobox 2 [Homo sapiens]
          Length = 310

 Score = 73.6 bits (179), Expect = 1e-13
 Identities = 39/80 (48%), Positives = 52/80 (65%), Gaps = 3/80 (3%)

Query: 102 SPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQV 161
           SP P  RR +    K R+ RT ++  QL  L  +F+ T+YL++ ER  LA  L LT+TQV
Sbjct: 148 SPRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQV 207

Query: 162 KIWFQNKRSKYKKLLKQNSG 181
           KIWFQN+R+K+K   KQN G
Sbjct: 208 KIWFQNRRTKWK---KQNPG 224


>gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 73.6 bits (179), Expect = 1e-13
 Identities = 39/80 (48%), Positives = 52/80 (65%), Gaps = 3/80 (3%)

Query: 102 SPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQV 161
           SP P  RR +    K R+ RT ++  QL  L  +F+ T+YL++ ER  LA  L LT+TQV
Sbjct: 170 SPRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQV 229

Query: 162 KIWFQNKRSKYKKLLKQNSG 181
           KIWFQN+R+K+K   KQN G
Sbjct: 230 KIWFQNRRTKWK---KQNPG 246


>gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 73.6 bits (179), Expect = 1e-13
 Identities = 39/80 (48%), Positives = 52/80 (65%), Gaps = 3/80 (3%)

Query: 102 SPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQV 161
           SP P  RR +    K R+ RT ++  QL  L  +F+ T+YL++ ER  LA  L LT+TQV
Sbjct: 170 SPRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQV 229

Query: 162 KIWFQNKRSKYKKLLKQNSG 181
           KIWFQN+R+K+K   KQN G
Sbjct: 230 KIWFQNRRTKWK---KQNPG 246


>gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]
          Length = 653

 Score = 73.6 bits (179), Expect = 1e-13
 Identities = 64/185 (34%), Positives = 87/185 (47%), Gaps = 20/185 (10%)

Query: 32  PLGLSPT-TAASPNLSYSRPYGHLLSYPYTEPANPGDSYLSCQQPAALSQPLCGPAEHPQ 90
           P G +PT T A P+ +  RP       P T    PG    S   P A   P  G A  P 
Sbjct: 15  PRGATPTCTPAQPSWARLRPT-RPPEPPSTRQRPPGPRENS---PVAPGPP--GGAAAPG 68

Query: 91  ELEADSEKPRLSPEPSERRPQAPAK--KLRKPRTIYSSLQLQHLNQRFQHTQYLALPERA 148
                 +    + +P  +R  + +K  K R+ RT ++  QL  L  +F+ T+YL++ ER 
Sbjct: 69  GAGTTPQGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERL 128

Query: 149 QLAAQLGLTQTQVKIWFQNKRSKYKKL-----LKQNSGGQEGDFPGR------TFSVSPC 197
            LA  L LT+TQVKIWFQN+R+K+KK          +GG  G  PG          +SP 
Sbjct: 129 NLALSLSLTETQVKIWFQNRRTKWKKQNPGADTSAPTGGGGGPGPGAGPGTGLPGGLSPL 188

Query: 198 SPPLP 202
           SP  P
Sbjct: 189 SPSPP 193


>gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 73.6 bits (179), Expect = 1e-13
 Identities = 39/80 (48%), Positives = 52/80 (65%), Gaps = 3/80 (3%)

Query: 102 SPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQV 161
           SP P  RR +    K R+ RT ++  QL  L  +F+ T+YL++ ER  LA  L LT+TQV
Sbjct: 170 SPRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQV 229

Query: 162 KIWFQNKRSKYKKLLKQNSG 181
           KIWFQN+R+K+K   KQN G
Sbjct: 230 KIWFQNRRTKWK---KQNPG 246


>gi|31377777 NK2 homeobox 8 [Homo sapiens]
          Length = 239

 Score = 73.6 bits (179), Expect = 1e-13
 Identities = 60/184 (32%), Positives = 80/184 (43%), Gaps = 41/184 (22%)

Query: 91  ELEADSEKPRLSPEPSER--RPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERA 148
           E   ++  P  S  PS R   P + A+K +K R ++S  Q   L +RF+  +YL+ PER 
Sbjct: 56  ESSLETSPPDSSQRPSARPASPGSDAEKRKKRRVLFSKAQTLELERRFRQQRYLSAPERE 115

Query: 149 QLAAQLGLTQTQVKIWFQNKRSKYKK-----------------------LLK-------- 177
           QLA+ L LT TQVKIWFQN R K K+                       LL+        
Sbjct: 116 QLASLLRLTPTQVKIWFQNHRYKLKRARAPGAAESPDLAASAELHAAPGLLRRVVVPVLV 175

Query: 178 ---QNSGGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGTLPTSGYGNSFGAW--YQHHSSD 232
              Q  GG  G   G   +   C  P  +   LP     P  G G++ G +  YQH +S 
Sbjct: 176 RDGQPCGGGGGGEVGTAAAQEKCGAPPAAACPLP---GYPAFGPGSALGLFPAYQHLASP 232

Query: 233 VLAS 236
            L S
Sbjct: 233 ALVS 236


>gi|4502365 NK3 homeobox 2 [Homo sapiens]
          Length = 333

 Score = 73.6 bits (179), Expect = 1e-13
 Identities = 35/68 (51%), Positives = 46/68 (67%)

Query: 107 ERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQ 166
           E  P AP  + ++ R  +S  Q+  L +RF H +YL+ PERA LAA L LT+TQVKIWFQ
Sbjct: 196 EEEPAAPKPRKKRSRAAFSHAQVFELERRFNHQRYLSGPERADLAASLKLTETQVKIWFQ 255

Query: 167 NKRSKYKK 174
           N+R K K+
Sbjct: 256 NRRYKTKR 263


>gi|24497513 homeobox A3 isoform a [Homo sapiens]
          Length = 443

 Score = 72.8 bits (177), Expect = 3e-13
 Identities = 60/184 (32%), Positives = 82/184 (44%), Gaps = 19/184 (10%)

Query: 23  PVPSVAAAYPLGLSPTTAASPNLSYSRPYGHLLSYPYTEPANPGDSYLSCQQPAALSQPL 82
           P P      P   +PT AA P  S + P  +  + P   PAN   S L       L+ P 
Sbjct: 100 PAPQPPQPAPQPPAPTPAAPPPPSSASPPQNASNNP--TPANAAKSPL-------LNSPT 150

Query: 83  CGPAEHPQELEA-DSEKPRLSPEPS------ERRPQAPAKKLRKPRTIYSSLQLQHLNQR 135
                 P   E+  + K + S   S      ++ P   A   ++ RT Y+S QL  L + 
Sbjct: 151 VAKQIFPWMKESRQNTKQKTSSSSSGESCAGDKSPPGQASS-KRARTAYTSAQLVELEKE 209

Query: 136 FQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVS 195
           F   +YL  P R ++A  L LT+ Q+KIWFQN+R KYKK   Q   G      G++ S S
Sbjct: 210 FHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK--DQKGKGMLTSSGGQSPSRS 267

Query: 196 PCSP 199
           P  P
Sbjct: 268 PVPP 271


>gi|13562112 homeobox A3 isoform a [Homo sapiens]
          Length = 443

 Score = 72.8 bits (177), Expect = 3e-13
 Identities = 60/184 (32%), Positives = 82/184 (44%), Gaps = 19/184 (10%)

Query: 23  PVPSVAAAYPLGLSPTTAASPNLSYSRPYGHLLSYPYTEPANPGDSYLSCQQPAALSQPL 82
           P P      P   +PT AA P  S + P  +  + P   PAN   S L       L+ P 
Sbjct: 100 PAPQPPQPAPQPPAPTPAAPPPPSSASPPQNASNNP--TPANAAKSPL-------LNSPT 150

Query: 83  CGPAEHPQELEA-DSEKPRLSPEPS------ERRPQAPAKKLRKPRTIYSSLQLQHLNQR 135
                 P   E+  + K + S   S      ++ P   A   ++ RT Y+S QL  L + 
Sbjct: 151 VAKQIFPWMKESRQNTKQKTSSSSSGESCAGDKSPPGQASS-KRARTAYTSAQLVELEKE 209

Query: 136 FQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVS 195
           F   +YL  P R ++A  L LT+ Q+KIWFQN+R KYKK   Q   G      G++ S S
Sbjct: 210 FHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK--DQKGKGMLTSSGGQSPSRS 267

Query: 196 PCSP 199
           P  P
Sbjct: 268 PVPP 271


>gi|89257348 homeo box HB9 [Homo sapiens]
          Length = 401

 Score = 72.0 bits (175), Expect = 4e-13
 Identities = 62/178 (34%), Positives = 87/178 (48%), Gaps = 29/178 (16%)

Query: 22  APVPSVAAAYP---LGLSPTTAAS------PNLSYSRPYGHLLSYPYTEPANPGDSYLSC 72
           A +P+ AA Y     G S   AA+      P LSYS P           PA+P D     
Sbjct: 150 AGLPAQAALYGHPVYGYSAAAAAAALAGQHPALSYSYP-----QVQGAHPAHPAD----- 199

Query: 73  QQPAALSQPLCGPAEHPQELEADSEKPRLSPEPSERRPQAPAK---KLRKPRTIYSSLQL 129
             P  L     G  +  Q L A S    + P+  +   QA +    K R+PRT ++S QL
Sbjct: 200 --PIKLG---AGTFQLDQWLRA-STAGMILPKMPDFNSQAQSNLLGKCRRPRTAFTSQQL 253

Query: 130 QHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLK-QNSGGQEGD 186
             L  +F+  +YL+ P+R ++A  L LT+TQVKIWFQN+R K+K+  K +    QE +
Sbjct: 254 LELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKKAKEQAAQEAE 311


>gi|7710121 engrailed homeobox 2 [Homo sapiens]
          Length = 333

 Score = 71.2 bits (173), Expect = 7e-13
 Identities = 33/79 (41%), Positives = 50/79 (63%)

Query: 96  SEKPRLSPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLG 155
           S++P   P   + + + P K+ ++PRT +++ QLQ L   FQ  +YL    R  LA +L 
Sbjct: 223 SDRPSSGPRSRKPKKKNPNKEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELS 282

Query: 156 LTQTQVKIWFQNKRSKYKK 174
           L ++Q+KIWFQNKR+K KK
Sbjct: 283 LNESQIKIWFQNKRAKIKK 301


>gi|70608170 H6 family homeobox 2 [Homo sapiens]
          Length = 273

 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 42/103 (40%), Positives = 57/103 (55%), Gaps = 8/103 (7%)

Query: 81  PLCGPAEHPQELEADSEKPRLSPEPSERRP-------QAPAKKLRKPRTIYSSLQLQHLN 133
           P   P+    + E +   P  SP P   RP       QA A K +K RT++S  Q+  L 
Sbjct: 107 PFLSPSHSDFKEEKERLLPAGSPSPGSERPRDGGAERQAGAAK-KKTRTVFSRSQVYQLE 165

Query: 134 QRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLL 176
             F   +YL+  ERA LA+ L LT+TQVK WFQN+R+K+K+ L
Sbjct: 166 STFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQL 208


>gi|39930383 BarH-like homeobox 2 [Homo sapiens]
          Length = 387

 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 43/139 (30%), Positives = 68/139 (48%), Gaps = 6/139 (4%)

Query: 42  SPNLSYSRPYGHLLSYPYTEPANPGDSYLSCQQPAALSQPLCGPAEHPQELEAD------ 95
           S  L+   PY   +S P+  P    ++     +P    +      +  ++ ++D      
Sbjct: 151 SKPLAACAPYSTSVSSPHHTPKQESNAVHESFRPKLEQEDSKTKLDKREDSQSDIKCHGT 210

Query: 96  SEKPRLSPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLG 155
            E+       S   P   AKK RK RT +S  QL  L + F+  +YL++ +R  LAA L 
Sbjct: 211 KEEGDREITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALN 270

Query: 156 LTQTQVKIWFQNKRSKYKK 174
           LT TQVK W+QN+R+K+K+
Sbjct: 271 LTDTQVKTWYQNRRTKWKR 289


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.130    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,101,299
Number of Sequences: 37866
Number of extensions: 700059
Number of successful extensions: 3330
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 297
Number of HSP's successfully gapped in prelim test: 209
Number of HSP's that attempted gapping in prelim test: 2775
Number of HSP's gapped (non-prelim): 741
length of query: 240
length of database: 18,247,518
effective HSP length: 99
effective length of query: 141
effective length of database: 14,498,784
effective search space: 2044328544
effective search space used: 2044328544
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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