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Search of human proteins with 20070199
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20070199 nuclear receptor subfamily 2, group F, member 6
[Homo sapiens]
(404 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Hom... 817 0.0
gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo... 501 e-142
gi|14149746 nuclear receptor subfamily 2, group F, member 2 isof... 499 e-141
gi|223555949 nuclear receptor subfamily 2, group F, member 2 iso... 352 4e-97
gi|223555953 nuclear receptor subfamily 2, group F, member 2 iso... 345 3e-95
gi|223555951 nuclear receptor subfamily 2, group F, member 2 iso... 345 3e-95
gi|7657395 photoreceptor-specific nuclear receptor isoform b [Ho... 276 2e-74
gi|4506755 retinoid X receptor, alpha [Homo sapiens] 274 1e-73
gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens] 272 4e-73
gi|11415052 retinoid X receptor, beta [Homo sapiens] 269 3e-72
gi|4507537 nuclear receptor subfamily 2, group E, member 1 [Homo... 246 2e-65
gi|7706515 photoreceptor-specific nuclear receptor isoform a [Ho... 236 3e-62
gi|31077207 hepatocyte nuclear factor 4 alpha isoform a [Homo sa... 229 4e-60
gi|31077205 hepatocyte nuclear factor 4 alpha isoform b [Homo sa... 229 4e-60
gi|71725341 hepatocyte nuclear factor 4 alpha isoform e [Homo sa... 229 4e-60
gi|71725339 hepatocyte nuclear factor 4 alpha isoform d [Homo sa... 229 4e-60
gi|31077209 hepatocyte nuclear factor 4 alpha isoform c [Homo sa... 226 4e-59
gi|71725336 hepatocyte nuclear factor 4 alpha isoform f [Homo sa... 226 4e-59
gi|115583654 hepatocyte nuclear factor 4, gamma [Homo sapiens] 219 3e-57
gi|238550159 estrogen-related receptor beta [Homo sapiens] 190 2e-48
gi|18860920 estrogen-related receptor alpha [Homo sapiens] 189 5e-48
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens] 186 4e-47
gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens] 183 2e-46
gi|45545429 estrogen-related receptor gamma isoform 2 [Homo sapi... 180 2e-45
gi|45545427 estrogen-related receptor gamma isoform 2 [Homo sapi... 180 2e-45
gi|45545433 estrogen-related receptor gamma isoform 1 [Homo sapi... 180 2e-45
gi|197209821 estrogen-related receptor gamma isoform 2 [Homo sap... 180 2e-45
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 176 3e-44
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 176 3e-44
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens] 176 3e-44
>gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Homo
sapiens]
Length = 404
Score = 817 bits (2111), Expect = 0.0
Identities = 404/404 (100%), Positives = 404/404 (100%)
Query: 1 MAMVTGGWGGPGGDTNGVDKAGGYPRAAEDDSASPPGAASDAEPGDEERPGLQVDCVVCG 60
MAMVTGGWGGPGGDTNGVDKAGGYPRAAEDDSASPPGAASDAEPGDEERPGLQVDCVVCG
Sbjct: 1 MAMVTGGWGGPGGDTNGVDKAGGYPRAAEDDSASPPGAASDAEPGDEERPGLQVDCVVCG 60
Query: 61 DKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVG 120
DKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVG
Sbjct: 61 DKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVG 120
Query: 121 MRKEAVQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQLLRAEPYP 180
MRKEAVQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQLLRAEPYP
Sbjct: 121 MRKEAVQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQLLRAEPYP 180
Query: 181 AAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQVALLRLSWS 240
AAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQVALLRLSWS
Sbjct: 181 AAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQVALLRLSWS 240
Query: 241 ELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDSA 300
ELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDSA
Sbjct: 241 ELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDSA 300
Query: 301 EYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGRLLLRLPAL 360
EYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGRLLLRLPAL
Sbjct: 301 EYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGRLLLRLPAL 360
Query: 361 RAVPASLISQLFFMRLVGKTPIETLIRDMLLSGSTFNWPYGSGQ 404
RAVPASLISQLFFMRLVGKTPIETLIRDMLLSGSTFNWPYGSGQ
Sbjct: 361 RAVPASLISQLFFMRLVGKTPIETLIRDMLLSGSTFNWPYGSGQ 404
>gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo
sapiens]
Length = 423
Score = 501 bits (1291), Expect = e-142
Identities = 261/434 (60%), Positives = 309/434 (71%), Gaps = 43/434 (9%)
Query: 1 MAMVTGGWGGPGGDTNGVDKAGGYPRAA--------------EDDSASPPGAASDAEPGD 46
MAMV W P D G + G P A + S +P + +PG
Sbjct: 1 MAMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGAGEQQQQAGSGAPHTPQTPGQPGA 60
Query: 47 EERPGL----------------QVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSY 90
PG ++CVVCGDKSSGKHYG FTCEGCKSFFKRS+RRNL+Y
Sbjct: 61 PATPGTAGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTY 120
Query: 91 TCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSLPGAVAASSGSPPGSA 150
TCR+NR+C IDQHHRNQCQYCRLKKC +VGMR+EAVQRGR+P + P PG
Sbjct: 121 TCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPN---------PGQY 171
Query: 151 LAAVASGGDLFPGQPVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLL 210
A+ +G L +S I+ LLRAEPYP + R+G+ ++GI+N+CELAARLL
Sbjct: 172 --ALTNGDPLNGHCYLSGYISLLLRAEPYPTS--RYGSQCMQPNNIMGIENICELAARLL 227
Query: 211 FSTVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPM 270
FS VEWAR+ PFFP+L + DQV+LLRL+WSELFVLNAAQ ++PLH APLLAAAGLHA+PM
Sbjct: 228 FSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPM 287
Query: 271 AAERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEK 330
+A+R VAFMD +R FQEQV+KL L VDSAEY CLKAI LFT DACGLSD AH+ESLQEK
Sbjct: 288 SADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEK 347
Query: 331 AQVALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDML 390
+Q AL EYVR+QYP+QP RFG+LLLRLP+LR V +S+I QLFF+RLVGKTPIETLIRDML
Sbjct: 348 SQCALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 407
Query: 391 LSGSTFNWPYGSGQ 404
LSGS+FNWPY S Q
Sbjct: 408 LSGSSFNWPYMSIQ 421
>gi|14149746 nuclear receptor subfamily 2, group F, member 2 isoform
a [Homo sapiens]
Length = 414
Score = 499 bits (1285), Expect = e-141
Identities = 258/398 (64%), Positives = 300/398 (75%), Gaps = 31/398 (7%)
Query: 5 TGGWGGPGGDTNGVDKAGGYPRAAEDDSASPPGAASDAEPGDEERPGLQVDCVVCGDKSS 64
T G GGP T AGG P G SD + + ++CVVCGDKSS
Sbjct: 42 TPGQGGPAS-TPAQTAAGG--------QGGPGGPGSDKQQQQQH-----IECVVCGDKSS 87
Query: 65 GKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKE 124
GKHYG FTCEGCKSFFKRS+RRNLSYTCR+NR+C IDQHHRNQCQYCRLKKC +VGMR+E
Sbjct: 88 GKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRRE 147
Query: 125 AVQRGRIPHSLP--GAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQLLRAEPYPAA 182
AVQRGR+P + P G A ++G P L +S I+ LLRAEPYP +
Sbjct: 148 AVQRGRMPPTQPTHGQFALTNGDP-------------LNCHSYLSGYISLLLRAEPYPTS 194
Query: 183 AGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQVALLRLSWSEL 242
RFG+ ++GI+N+CELAAR+LFS VEWAR+ PFFP+L + DQVALLRL+WSEL
Sbjct: 195 --RFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSEL 252
Query: 243 FVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDSAEY 302
FVLNAAQ ++PLH APLLAAAGLHA+PM+A+R VAFMD +R FQEQV+KL L VDSAEY
Sbjct: 253 FVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEY 312
Query: 303 GCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGRLLLRLPALRA 362
CLKAI LFT DACGLSD AHVESLQEK+Q AL EYVR+QYP+QP RFG+LLLRLP+LR
Sbjct: 313 SCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRT 372
Query: 363 VPASLISQLFFMRLVGKTPIETLIRDMLLSGSTFNWPY 400
V +S+I QLFF+RLVGKTPIETLIRDMLLSGS+FNWPY
Sbjct: 373 VSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPY 410
>gi|223555949 nuclear receptor subfamily 2, group F, member 2
isoform b [Homo sapiens]
Length = 281
Score = 352 bits (902), Expect = 4e-97
Identities = 184/278 (66%), Positives = 217/278 (78%), Gaps = 17/278 (6%)
Query: 125 AVQRGRIPHSLP--GAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQLLRAEPYPAA 182
AVQRGR+P + P G A ++G P L +S I+ LLRAEPYP +
Sbjct: 15 AVQRGRMPPTQPTHGQFALTNGDP-------------LNCHSYLSGYISLLLRAEPYPTS 61
Query: 183 AGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQVALLRLSWSEL 242
RFG+ ++GI+N+CELAAR+LFS VEWAR+ PFFP+L + DQVALLRL+WSEL
Sbjct: 62 --RFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSEL 119
Query: 243 FVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDSAEY 302
FVLNAAQ ++PLH APLLAAAGLHA+PM+A+R VAFMD +R FQEQV+KL L VDSAEY
Sbjct: 120 FVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEY 179
Query: 303 GCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGRLLLRLPALRA 362
CLKAI LFT DACGLSD AHVESLQEK+Q AL EYVR+QYP+QP RFG+LLLRLP+LR
Sbjct: 180 SCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRT 239
Query: 363 VPASLISQLFFMRLVGKTPIETLIRDMLLSGSTFNWPY 400
V +S+I QLFF+RLVGKTPIETLIRDMLLSGS+FNWPY
Sbjct: 240 VSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPY 277
>gi|223555953 nuclear receptor subfamily 2, group F, member 2
isoform c [Homo sapiens]
Length = 261
Score = 345 bits (886), Expect = 3e-95
Identities = 174/248 (70%), Positives = 205/248 (82%), Gaps = 2/248 (0%)
Query: 153 AVASGGDLFPGQPVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFS 212
A+ +G L +S I+ LLRAEPYP + RFG+ ++GI+N+CELAAR+LFS
Sbjct: 12 ALTNGDPLNCHSYLSGYISLLLRAEPYPTS--RFGSQCMQPNNIMGIENICELAARMLFS 69
Query: 213 TVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAA 272
VEWAR+ PFFP+L + DQVALLRL+WSELFVLNAAQ ++PLH APLLAAAGLHA+PM+A
Sbjct: 70 AVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSA 129
Query: 273 ERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQ 332
+R VAFMD +R FQEQV+KL L VDSAEY CLKAI LFT DACGLSD AHVESLQEK+Q
Sbjct: 130 DRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQ 189
Query: 333 VALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLS 392
AL EYVR+QYP+QP RFG+LLLRLP+LR V +S+I QLFF+RLVGKTPIETLIRDMLLS
Sbjct: 190 CALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLS 249
Query: 393 GSTFNWPY 400
GS+FNWPY
Sbjct: 250 GSSFNWPY 257
>gi|223555951 nuclear receptor subfamily 2, group F, member 2
isoform c [Homo sapiens]
Length = 261
Score = 345 bits (886), Expect = 3e-95
Identities = 174/248 (70%), Positives = 205/248 (82%), Gaps = 2/248 (0%)
Query: 153 AVASGGDLFPGQPVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFS 212
A+ +G L +S I+ LLRAEPYP + RFG+ ++GI+N+CELAAR+LFS
Sbjct: 12 ALTNGDPLNCHSYLSGYISLLLRAEPYPTS--RFGSQCMQPNNIMGIENICELAARMLFS 69
Query: 213 TVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAA 272
VEWAR+ PFFP+L + DQVALLRL+WSELFVLNAAQ ++PLH APLLAAAGLHA+PM+A
Sbjct: 70 AVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSA 129
Query: 273 ERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQ 332
+R VAFMD +R FQEQV+KL L VDSAEY CLKAI LFT DACGLSD AHVESLQEK+Q
Sbjct: 130 DRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQ 189
Query: 333 VALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLS 392
AL EYVR+QYP+QP RFG+LLLRLP+LR V +S+I QLFF+RLVGKTPIETLIRDMLLS
Sbjct: 190 CALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLS 249
Query: 393 GSTFNWPY 400
GS+FNWPY
Sbjct: 250 GSSFNWPY 257
>gi|7657395 photoreceptor-specific nuclear receptor isoform b [Homo
sapiens]
Length = 410
Score = 276 bits (707), Expect = 2e-74
Identities = 163/399 (40%), Positives = 212/399 (53%), Gaps = 35/399 (8%)
Query: 21 AGGYPRAAEDDSASPPGAASDAEPGDEERPGLQVDCVVCGDKSSGKHYGVFTCEGCKSFF 80
A P A PG E P LQ C VCGD SSGKHYG++ C GC FF
Sbjct: 14 AAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQ--CRVCGDSSSGKHYGIYACNGCSGFF 71
Query: 81 KRSIRRNLSYTCRSNRD-CQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSL---- 135
KRS+RR L Y C+ C +D+ HRNQCQ CRLKKC + GM ++AVQ R P S
Sbjct: 72 KRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQNERQPRSTAQVH 131
Query: 136 -----------------PGAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQLLRAEP 178
P A A S P AA A G +E A+L EP
Sbjct: 132 LDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITAETCAKL---EP 188
Query: 179 YPAAAG--------RFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVAD 230
A F + ++ + G+D++ E +ARLLF V+WA++ P F LP D
Sbjct: 189 EDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPVFSSLPFRD 248
Query: 231 QVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVD 290
QV LL +WSELF+L A Q +LPL + PLLA AA A R + R QE +
Sbjct: 249 QVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMETRVLQETIS 308
Query: 291 KLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRF 350
+ L VD E+ C+KA+ LF P+ GL DP HVE+LQ+++QV L+++ +A +PSQP RF
Sbjct: 309 RFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAHHPSQPVRF 368
Query: 351 GRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDM 389
G+LLL LP+LR + A I LFF + +G TP+E L+ DM
Sbjct: 369 GKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDM 407
>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
Length = 462
Score = 274 bits (700), Expect = 1e-73
Identities = 141/335 (42%), Positives = 196/335 (58%), Gaps = 14/335 (4%)
Query: 56 CVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKK 115
C +CGD+SSGKHYGV++CEGCK FFKR++R++L+YTCR N+DC ID+ RN+CQYCR +K
Sbjct: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194
Query: 116 CFRVGMRKEAVQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQLLR 175
C +GM++EAVQ R G V S PV ++ L
Sbjct: 195 CLAMGMKREAVQEER-----------QRGKDRNE--NEVESTSSANEDMPVERILEAELA 241
Query: 176 AEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQVALL 235
EP G + + N+C+ A + LF+ VEWA+ P F ELP+ DQV LL
Sbjct: 242 VEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILL 301
Query: 236 RLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGRL 295
R W+EL + + + ++ + +L A GLH +A A R E V K+ +
Sbjct: 302 RAGWNELLIASFSHRSIAVKDG-ILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDM 360
Query: 296 QVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGRLLL 355
Q+D E GCL+AI LF PD+ GLS+PA VE+L+EK +L Y + +YP QP RF +LLL
Sbjct: 361 QMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLL 420
Query: 356 RLPALRAVPASLISQLFFMRLVGKTPIETLIRDML 390
RLPALR++ + LFF +L+G TPI+T + +ML
Sbjct: 421 RLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 455
>gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
Length = 463
Score = 272 bits (695), Expect = 4e-73
Identities = 148/366 (40%), Positives = 207/366 (56%), Gaps = 19/366 (5%)
Query: 27 AAEDDSASP--PGAASDAEPGDEERPGLQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSI 84
++ED P PG + P ++ C +CGD+SSGKHYGV++CEGCK FFKR+I
Sbjct: 108 SSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTI 167
Query: 85 RRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSLPGAVAASSG 144
R++L YTCR N+DC ID+ RN+CQYCR +KC +GM++EAVQ R S
Sbjct: 168 RKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCLVMGMKREAVQEER---------QRSRE 218
Query: 145 SPPGSALAAVASGGDLFPGQPVSELIAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCE 204
A A + D+ PV ++ L EP + G V N+C
Sbjct: 219 RAESEAECATSGHEDM----PVERILEAELAVEPKTESYGDMNMENSTNDPV---TNICH 271
Query: 205 LAARLLFSTVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAG 264
A + LF+ VEWA+ P F +L + DQV LLR W+EL + + + ++ + +L A G
Sbjct: 272 AADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDG-ILLATG 330
Query: 265 LHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHV 324
LH +A A R E V K+ +Q+D +E GCL+AI LF PDA GLS+P+ V
Sbjct: 331 LHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEV 390
Query: 325 ESLQEKAQVALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIET 384
E+L+EK L Y + +YP QP RF +LLLRLPALR++ + LFF +L+G TPI+T
Sbjct: 391 ETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDT 450
Query: 385 LIRDML 390
+ +ML
Sbjct: 451 FLMEML 456
>gi|11415052 retinoid X receptor, beta [Homo sapiens]
Length = 533
Score = 269 bits (688), Expect = 3e-72
Identities = 138/337 (40%), Positives = 194/337 (57%), Gaps = 17/337 (5%)
Query: 56 CVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKK 115
C +CGD+SSGKHYGV++CEGCK FFKR+IR++L+Y+CR N+DC +D+ RN+CQYCR +K
Sbjct: 205 CAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQK 264
Query: 116 CFRVGMRKEAVQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQLLR 175
C GM++EAVQ R +G P PV ++ L
Sbjct: 265 CLATGMKREAVQEERQRGKDKDGDGEGAGGAPEE--------------MPVDRILEAELA 310
Query: 176 AEPY--PAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQVA 233
E G G GG + + N+C+ A + LF+ VEWA+ P F LP+ DQV
Sbjct: 311 VEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVI 370
Query: 234 LLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKLG 293
LLR W+EL + + + ++ + +L A GLH +A A R E V K+
Sbjct: 371 LLRAGWNELLIASFSHRSIDVRDG-ILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMR 429
Query: 294 RLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGRL 353
+++D E GCL+AI LF PDA GLS+P+ VE L+EK +L Y + +YP Q RF +L
Sbjct: 430 DMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKL 489
Query: 354 LLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDML 390
LLRLPALR++ + LFF +L+G TPI+T + +ML
Sbjct: 490 LLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEML 526
>gi|4507537 nuclear receptor subfamily 2, group E, member 1 [Homo
sapiens]
Length = 385
Score = 246 bits (629), Expect = 2e-65
Identities = 144/382 (37%), Positives = 206/382 (53%), Gaps = 52/382 (13%)
Query: 52 LQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRD--CQIDQHHRNQCQ 109
L + C VCGD+SSGKHYGV+ C+GC FFKRSIRRN +Y C+S C +D+ HRNQC+
Sbjct: 12 LDIPCKVCGDRSSGKHYGVYACDGCSGFFKRSIRRNRTYVCKSGNQGGCPVDKTHRNQCR 71
Query: 110 YCRLKKCFRVGMRKEAVQRGRIPHS-----------------------LPGAV------- 139
CRLKKC V M K+AVQ R P + P A
Sbjct: 72 ACRLKKCLEVNMNKDAVQHERGPRTSTIRKQVALYFRGHKEENGAAAHFPSAALPAPAFF 131
Query: 140 -AASSGSPPGSALAAVASGGDLFPGQPVSELIAQLLRAEP-YPAAAGRFGAGGGAAGAVL 197
A + P G LAAV++ P + + L + P YP G +
Sbjct: 132 TAVTQLEPHGLELAAVST-------TPERQTLVSLAQPTPKYPHEVN----GTPMYLYEV 180
Query: 198 GIDNVCELAARLLFSTVEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLHTA 257
++VCE AARLLF +++WA+ P F L + DQ+ LL +W ELFVL AQ A+P+
Sbjct: 181 ATESVCESAARLLFMSIKWAKSVPAFSTLSLQDQLMLLEDAWRELFVLGIAQWAIPVDAN 240
Query: 258 PLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALF--TPDA 315
LLA +G++ +++ + +++A QE V + +L++D+ E+ CLK I F P
Sbjct: 241 TLLAVSGMNGDNTDSQKLNKIISEIQALQEVVARFRQLRLDATEFACLKCIVTFKAVPTH 300
Query: 316 CG-----LSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQ 370
G + A + +LQ++AQ+ L Y+ +YP+QP RFG+LLL LPALR++ S I +
Sbjct: 301 SGSELRSFRNAAAIAALQDEAQLTLNSYIHTRYPTQPCRFGKLLLLLPALRSISPSTIEE 360
Query: 371 LFFMRLVGKTPIETLIRDMLLS 392
+FF + +G PI L+ DM S
Sbjct: 361 VFFKKTIGNVPITRLLSDMYKS 382
>gi|7706515 photoreceptor-specific nuclear receptor isoform a [Homo
sapiens]
Length = 367
Score = 236 bits (602), Expect = 3e-62
Identities = 142/359 (39%), Positives = 184/359 (51%), Gaps = 35/359 (9%)
Query: 21 AGGYPRAAEDDSASPPGAASDAEPGDEERPGLQVDCVVCGDKSSGKHYGVFTCEGCKSFF 80
A P A PG E P LQ C VCGD SSGKHYG++ C GC FF
Sbjct: 14 AAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQ--CRVCGDSSSGKHYGIYACNGCSGFF 71
Query: 81 KRSIRRNLSYTCRSNRD-CQIDQHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSL---- 135
KRS+RR L Y C+ C +D+ HRNQCQ CRLKKC + GM ++AVQ R P S
Sbjct: 72 KRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQNERQPRSTAQVH 131
Query: 136 -----------------PGAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQLLRAEP 178
P A A S P AA A G +E A+L EP
Sbjct: 132 LDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITAETCAKL---EP 188
Query: 179 YPAAAG--------RFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVAD 230
A F + ++ + G+D++ E +ARLLF V+WA++ P F LP D
Sbjct: 189 EDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPVFSSLPFRD 248
Query: 231 QVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVD 290
QV LL +WSELF+L A Q +LPL + PLLA AA A R + R QE +
Sbjct: 249 QVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMETRVLQETIS 308
Query: 291 KLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQR 349
+ L VD E+ C+KA+ LF P+ GL DP HVE+LQ+++QV L+++ +A +PSQP R
Sbjct: 309 RFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAHHPSQPVR 367
>gi|31077207 hepatocyte nuclear factor 4 alpha isoform a [Homo
sapiens]
Length = 464
Score = 229 bits (583), Expect = 4e-60
Identities = 135/353 (38%), Positives = 191/353 (54%), Gaps = 26/353 (7%)
Query: 51 GLQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQY 110
G+ C +CGD+++GKHYG +C+GCK FF+RS+R+N Y+CR +R C +D+ RNQC+Y
Sbjct: 55 GVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRY 114
Query: 111 CRLKKCFRVGMRKEAVQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELI 170
CRLKKCFR GM+KEAVQ R S + S P +AL L
Sbjct: 115 CRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINAL-----------------LQ 157
Query: 171 AQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVAD 230
A++L + +G G A + I +VCE L VEWA++ P F ELP+ D
Sbjct: 158 AEVLSRQITSPVSGI--NGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDD 215
Query: 231 QVALLRLSWSELFVLNAAQAALPLHTAPLLA---AAGLHAAPMAAERAVAFMDQVRAFQE 287
QVALLR E +L A + ++ LL H +A V+ +R E
Sbjct: 216 QVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVS----IRILDE 271
Query: 288 QVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQP 347
V LQ+D EY LKAI F PDA GLSDP ++ L+ + QV+L +Y+ +
Sbjct: 272 LVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSR 331
Query: 348 QRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLSGSTFNWPY 400
RFG LLL LP L+++ +I Q+ F++L G I+ L+++MLL GS + P+
Sbjct: 332 GRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPH 384
>gi|31077205 hepatocyte nuclear factor 4 alpha isoform b [Homo
sapiens]
Length = 474
Score = 229 bits (583), Expect = 4e-60
Identities = 135/353 (38%), Positives = 191/353 (54%), Gaps = 26/353 (7%)
Query: 51 GLQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQY 110
G+ C +CGD+++GKHYG +C+GCK FF+RS+R+N Y+CR +R C +D+ RNQC+Y
Sbjct: 55 GVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRY 114
Query: 111 CRLKKCFRVGMRKEAVQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELI 170
CRLKKCFR GM+KEAVQ R S + S P +AL L
Sbjct: 115 CRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINAL-----------------LQ 157
Query: 171 AQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVAD 230
A++L + +G G A + I +VCE L VEWA++ P F ELP+ D
Sbjct: 158 AEVLSRQITSPVSGI--NGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDD 215
Query: 231 QVALLRLSWSELFVLNAAQAALPLHTAPLLA---AAGLHAAPMAAERAVAFMDQVRAFQE 287
QVALLR E +L A + ++ LL H +A V+ +R E
Sbjct: 216 QVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVS----IRILDE 271
Query: 288 QVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQP 347
V LQ+D EY LKAI F PDA GLSDP ++ L+ + QV+L +Y+ +
Sbjct: 272 LVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSR 331
Query: 348 QRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLSGSTFNWPY 400
RFG LLL LP L+++ +I Q+ F++L G I+ L+++MLL GS + P+
Sbjct: 332 GRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPH 384
>gi|71725341 hepatocyte nuclear factor 4 alpha isoform e [Homo
sapiens]
Length = 442
Score = 229 bits (583), Expect = 4e-60
Identities = 135/353 (38%), Positives = 191/353 (54%), Gaps = 26/353 (7%)
Query: 51 GLQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQY 110
G+ C +CGD+++GKHYG +C+GCK FF+RS+R+N Y+CR +R C +D+ RNQC+Y
Sbjct: 33 GVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRY 92
Query: 111 CRLKKCFRVGMRKEAVQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELI 170
CRLKKCFR GM+KEAVQ R S + S P +AL L
Sbjct: 93 CRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINAL-----------------LQ 135
Query: 171 AQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVAD 230
A++L + +G G A + I +VCE L VEWA++ P F ELP+ D
Sbjct: 136 AEVLSRQITSPVSGI--NGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDD 193
Query: 231 QVALLRLSWSELFVLNAAQAALPLHTAPLLA---AAGLHAAPMAAERAVAFMDQVRAFQE 287
QVALLR E +L A + ++ LL H +A V+ +R E
Sbjct: 194 QVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVS----IRILDE 249
Query: 288 QVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQP 347
V LQ+D EY LKAI F PDA GLSDP ++ L+ + QV+L +Y+ +
Sbjct: 250 LVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSR 309
Query: 348 QRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLSGSTFNWPY 400
RFG LLL LP L+++ +I Q+ F++L G I+ L+++MLL GS + P+
Sbjct: 310 GRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPH 362
>gi|71725339 hepatocyte nuclear factor 4 alpha isoform d [Homo
sapiens]
Length = 452
Score = 229 bits (583), Expect = 4e-60
Identities = 135/353 (38%), Positives = 191/353 (54%), Gaps = 26/353 (7%)
Query: 51 GLQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQY 110
G+ C +CGD+++GKHYG +C+GCK FF+RS+R+N Y+CR +R C +D+ RNQC+Y
Sbjct: 33 GVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRY 92
Query: 111 CRLKKCFRVGMRKEAVQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELI 170
CRLKKCFR GM+KEAVQ R S + S P +AL L
Sbjct: 93 CRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINAL-----------------LQ 135
Query: 171 AQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVAD 230
A++L + +G G A + I +VCE L VEWA++ P F ELP+ D
Sbjct: 136 AEVLSRQITSPVSGI--NGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDD 193
Query: 231 QVALLRLSWSELFVLNAAQAALPLHTAPLLA---AAGLHAAPMAAERAVAFMDQVRAFQE 287
QVALLR E +L A + ++ LL H +A V+ +R E
Sbjct: 194 QVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVS----IRILDE 249
Query: 288 QVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQP 347
V LQ+D EY LKAI F PDA GLSDP ++ L+ + QV+L +Y+ +
Sbjct: 250 LVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSR 309
Query: 348 QRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLSGSTFNWPY 400
RFG LLL LP L+++ +I Q+ F++L G I+ L+++MLL GS + P+
Sbjct: 310 GRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGGSPSDAPH 362
>gi|31077209 hepatocyte nuclear factor 4 alpha isoform c [Homo
sapiens]
Length = 417
Score = 226 bits (575), Expect = 4e-59
Identities = 133/346 (38%), Positives = 187/346 (54%), Gaps = 26/346 (7%)
Query: 51 GLQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQY 110
G+ C +CGD+++GKHYG +C+GCK FF+RS+R+N Y+CR +R C +D+ RNQC+Y
Sbjct: 55 GVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRY 114
Query: 111 CRLKKCFRVGMRKEAVQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELI 170
CRLKKCFR GM+KEAVQ R S + S P +AL L
Sbjct: 115 CRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINAL-----------------LQ 157
Query: 171 AQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVAD 230
A++L + +G G A + I +VCE L VEWA++ P F ELP+ D
Sbjct: 158 AEVLSRQITSPVSGI--NGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDD 215
Query: 231 QVALLRLSWSELFVLNAAQAALPLHTAPLLA---AAGLHAAPMAAERAVAFMDQVRAFQE 287
QVALLR E +L A + ++ LL H +A V+ +R E
Sbjct: 216 QVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVS----IRILDE 271
Query: 288 QVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQP 347
V LQ+D EY LKAI F PDA GLSDP ++ L+ + QV+L +Y+ +
Sbjct: 272 LVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSR 331
Query: 348 QRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLSG 393
RFG LLL LP L+++ +I Q+ F++L G I+ L+++MLL G
Sbjct: 332 GRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGG 377
>gi|71725336 hepatocyte nuclear factor 4 alpha isoform f [Homo
sapiens]
Length = 395
Score = 226 bits (575), Expect = 4e-59
Identities = 133/346 (38%), Positives = 187/346 (54%), Gaps = 26/346 (7%)
Query: 51 GLQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQY 110
G+ C +CGD+++GKHYG +C+GCK FF+RS+R+N Y+CR +R C +D+ RNQC+Y
Sbjct: 33 GVSALCAICGDRATGKHYGASSCDGCKGFFRRSVRKNHMYSCRFSRQCVVDKDKRNQCRY 92
Query: 111 CRLKKCFRVGMRKEAVQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELI 170
CRLKKCFR GM+KEAVQ R S + S P +AL L
Sbjct: 93 CRLKKCFRAGMKKEAVQNERDRISTRRSSYEDSSLPSINAL-----------------LQ 135
Query: 171 AQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVAD 230
A++L + +G G A + I +VCE L VEWA++ P F ELP+ D
Sbjct: 136 AEVLSRQITSPVSGI--NGDIRAKKIASIADVCESMKEQLLVLVEWAKYIPAFCELPLDD 193
Query: 231 QVALLRLSWSELFVLNAAQAALPLHTAPLLA---AAGLHAAPMAAERAVAFMDQVRAFQE 287
QVALLR E +L A + ++ LL H +A V+ +R E
Sbjct: 194 QVALLRAHAGEHLLLGATKRSMVFKDVLLLGNDYIVPRHCPELAEMSRVS----IRILDE 249
Query: 288 QVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQP 347
V LQ+D EY LKAI F PDA GLSDP ++ L+ + QV+L +Y+ +
Sbjct: 250 LVLPFQELQIDDNEYAYLKAIIFFDPDAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSR 309
Query: 348 QRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLSG 393
RFG LLL LP L+++ +I Q+ F++L G I+ L+++MLL G
Sbjct: 310 GRFGELLLLLPTLQSITWQMIEQIQFIKLFGMAKIDNLLQEMLLGG 355
>gi|115583654 hepatocyte nuclear factor 4, gamma [Homo sapiens]
Length = 445
Score = 219 bits (558), Expect = 3e-57
Identities = 125/346 (36%), Positives = 188/346 (54%), Gaps = 23/346 (6%)
Query: 51 GLQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQY 110
G+ C +CGD+++GKHYG +C+GCK FF+RSIR++ Y+CR +R C +D+ RNQC+Y
Sbjct: 44 GVNCLCAICGDRATGKHYGASSCDGCKGFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRY 103
Query: 111 CRLKKCFRVGMRKEAVQRGRIPHSLPGAVAASSGSPPGSALA-AVASGGDLFPGQPVSEL 169
CRL+KCFR GM+KEAVQ R S + S P + LA A + P S
Sbjct: 104 CRLRKCFRAGMKKEAVQNERDRISTRRSTFDGSNIPSINTLAQAEVRSRQISVSSPGSST 163
Query: 170 IAQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVA 229
+ + + I +VCE + L VEWA++ P F ELP+
Sbjct: 164 DINVKK--------------------IASIGDVCESMKQQLLVLVEWAKYIPAFCELPLD 203
Query: 230 DQVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQV 289
DQVALLR E +L A + ++ ++ LL + E ++ + R E V
Sbjct: 204 DQVALLRAHAGEHLLLGATKRSM-MYKDILLLGNNYVIHRNSCEVEISRVAN-RVLDELV 261
Query: 290 DKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQR 349
+Q+D EY CLKAI F PDA GLSDP +++++ + Q+ L +Y+ + R
Sbjct: 262 RPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYDSRGR 321
Query: 350 FGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLSGST 395
FG LLL LP L+++ +I Q+ F++L G I+ L+++MLL G++
Sbjct: 322 FGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGAS 367
>gi|238550159 estrogen-related receptor beta [Homo sapiens]
Length = 508
Score = 190 bits (482), Expect = 2e-48
Identities = 113/336 (33%), Positives = 174/336 (51%), Gaps = 10/336 (2%)
Query: 56 CVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKK 115
C+VCGD +SG HYGV +CE CK+FFKR+I+ N+ Y+C + +C+I + R CQ CR K
Sbjct: 103 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 162
Query: 116 CFRVGMRKEAVQRGRIPHSLPGAVAA-SSGSPPGSALAAVASGGDLFPGQPVSELIAQLL 174
C +VGM KE V+ R+ S S P +L +P++++++ LL
Sbjct: 163 CLKVGMLKEGVRLDRVRGGRQKYKRRLDSESSPYLSLQISPPAK-----KPLTKIVSYLL 217
Query: 175 RAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQVAL 234
AEP A G G + + +C+LA R L + WA+H P F L + DQ++L
Sbjct: 218 VAEPDKLYA--MPPPGMPEGDIKALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSL 275
Query: 235 LRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGR 294
L+ +W E+ +L +LP L A + R ++ RA + V + +
Sbjct: 276 LQSAWMEILILGIVYRSLPYDDK--LVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKK 333
Query: 295 LQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGRLL 354
L+V+ E+ LKA+AL D+ + D V+ LQ+ AL +Y +Q +P R G+LL
Sbjct: 334 LKVEKEEFVTLKALALANSDSMYIEDLEAVQKLQDLLHEALQDYELSQRHEEPWRTGKLL 393
Query: 355 LRLPALRAVPASLISQLFFMRLVGKTPIETLIRDML 390
L LP LR A + + ++L GK P+ L +ML
Sbjct: 394 LTLPLLRQTAAKAVQHFYSVKLQGKVPMHKLFLEML 429
>gi|18860920 estrogen-related receptor alpha [Homo sapiens]
Length = 423
Score = 189 bits (479), Expect = 5e-48
Identities = 118/344 (34%), Positives = 175/344 (50%), Gaps = 13/344 (3%)
Query: 56 CVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKK 115
C+VCGD +SG HYGV +CE CK+FFKR+I+ ++ Y+C ++ +C+I + R CQ CR K
Sbjct: 79 CLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTK 138
Query: 116 CFRVGMRKEAVQRGRIPHSLPGAVAASSGSP-----PGSALAAVASGGDLFPGQPVSELI 170
C RVGM KE V+ R+ P P A +GG PV+ L+
Sbjct: 139 CLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALV 198
Query: 171 AQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVAD 230
+ LL EP A G G + + +C+L R + T+ WA+ P F L ++D
Sbjct: 199 SHLLVVEPEKLYA--MPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSD 256
Query: 231 QVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVD 290
Q+++L+ W E+ VL AQ +LPL LA A RA + A + V
Sbjct: 257 QMSVLQSVWMEVLVLGVAQRSLPLQDE--LAFAEDLVLDEEGARAAGLGELGAALLQLVR 314
Query: 291 KLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQY----PSQ 346
+L L+++ EY LKA+AL D+ + D VE L+E AL EY + ++
Sbjct: 315 RLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAE 374
Query: 347 PQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDML 390
+R GRLLL LP LR +++ + ++L GK P+ L +ML
Sbjct: 375 RRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEML 418
>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
Length = 443
Score = 186 bits (471), Expect = 4e-47
Identities = 137/412 (33%), Positives = 196/412 (47%), Gaps = 39/412 (9%)
Query: 7 GWGGPGGD-----TNGVDKAG----GYPRAAEDDSASPPGAASD----AEPGDEERPGLQ 53
G GPG T G AG +P+ A S +S+ + P P +
Sbjct: 17 GAAGPGAGLLRRATGGSCFAGLESFAWPQPASLQSVETQSTSSEEMVPSSPSPPPPPRVY 76
Query: 54 VDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRL 113
C VC DKSSG HYGV +CEGCK FF+RSI++N+ YTC +++C I++ RN+CQYCRL
Sbjct: 77 KPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRL 136
Query: 114 KKCFRVGMRKEAVQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQL 173
+KCF VGM KEAV+ R + GSP L+ + ELI ++
Sbjct: 137 QKCFEVGMSKEAVRNDR---NKKKKEVKEEGSPDSYELS-----------PQLEELITKV 182
Query: 174 LRA--EPYPAAA--GRFGAGGGAAGAV---LGI-DNVCELAARLLFSTVEWARHAPFFPE 225
+A E +P+ G++ A V LG+ D ELA + + VE+A+ P F
Sbjct: 183 SKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKIVEFAKRLPGFTG 242
Query: 226 LPVADQVALLRLSWSELFVLNAAQAALP-LHTAPLLAAAGLHAAPMAAERAVAFMDQVRA 284
L +ADQ+ LL+ + ++ +L P T L+ M D V A
Sbjct: 243 LSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFA 302
Query: 285 FQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYP 344
F Q L L++D E G L AI L D L +P V+ LQE AL Y R + P
Sbjct: 303 FAGQ---LLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRP 359
Query: 345 SQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLSGSTF 396
SQP F R+L+++ LR + + +++ P+ LIR+ML + F
Sbjct: 360 SQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPEMF 411
>gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]
Length = 454
Score = 183 bits (465), Expect = 2e-46
Identities = 125/364 (34%), Positives = 180/364 (49%), Gaps = 26/364 (7%)
Query: 42 AEPGDEERPGLQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQID 101
+ P P + C VC DKSSG HYGV +CEGCK FF+RSI++N+ YTC +++C I+
Sbjct: 76 SSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIIN 135
Query: 102 QHHRNQCQYCRLKKCFRVGMRKEAVQRGRIPHSLPGAVAASSGSPPGSALAAVASGGDLF 161
+ RN+CQYCRL+KCF VGM KEAV+ R + GSP L+
Sbjct: 136 KVTRNRCQYCRLQKCFEVGMSKEAVRNDR---NKKKKEVKEEGSPDSYELS--------- 183
Query: 162 PGQPVSELIAQLLRA--EPYPAAA--GRFGAGGGAAGAV---LGI-DNVCELAARLLFST 213
+ ELI ++ +A E +P+ G++ A V LG+ D ELA + +
Sbjct: 184 --PQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIKI 241
Query: 214 VEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALP-LHTAPLLAAAGLHAAPMAA 272
VE+A+ P F L +ADQ+ LL+ + ++ +L P T L+ M
Sbjct: 242 VEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMHN 301
Query: 273 ERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQ 332
D V AF Q L L++D E G L AI L D L +P V+ LQE
Sbjct: 302 AGFGPLTDLVFAFAGQ---LLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLL 358
Query: 333 VALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDMLLS 392
AL Y R + PSQP F R+L+++ LR + + +++ P+ LIR+ML +
Sbjct: 359 EALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLEN 418
Query: 393 GSTF 396
F
Sbjct: 419 PEMF 422
>gi|45545429 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 180 bits (457), Expect = 2e-45
Identities = 106/338 (31%), Positives = 168/338 (49%), Gaps = 14/338 (4%)
Query: 56 CVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKK 115
C+VCGD +SG HYGV +CE CK+FFKR+I+ N+ Y+C + +C+I + R CQ CR K
Sbjct: 105 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 164
Query: 116 CFRVGMRKEAVQRGRI---PHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQ 172
C +VGM KE V+ R+ + A + L A +P +++++
Sbjct: 165 CLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAK-------KPYNKIVSH 217
Query: 173 LLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQV 232
LL AEP A + + +C+LA R L + WA+H P F L +ADQ+
Sbjct: 218 LLVAEPEKIYA--MPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQM 275
Query: 233 ALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKL 292
+LL+ +W E+ +L +L L A + + +D A + V K
Sbjct: 276 SLLQSAWMEILILGVVYRSLSFEDE--LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKY 333
Query: 293 GRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGR 352
++++ E+ LKAIAL D+ + D V+ LQ+ AL +Y Q+ P+R G+
Sbjct: 334 KSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGK 393
Query: 353 LLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDML 390
+L+ LP LR + + ++L GK P+ L +ML
Sbjct: 394 MLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEML 431
>gi|45545427 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 180 bits (457), Expect = 2e-45
Identities = 106/338 (31%), Positives = 168/338 (49%), Gaps = 14/338 (4%)
Query: 56 CVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKK 115
C+VCGD +SG HYGV +CE CK+FFKR+I+ N+ Y+C + +C+I + R CQ CR K
Sbjct: 105 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 164
Query: 116 CFRVGMRKEAVQRGRI---PHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQ 172
C +VGM KE V+ R+ + A + L A +P +++++
Sbjct: 165 CLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAK-------KPYNKIVSH 217
Query: 173 LLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQV 232
LL AEP A + + +C+LA R L + WA+H P F L +ADQ+
Sbjct: 218 LLVAEPEKIYA--MPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQM 275
Query: 233 ALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKL 292
+LL+ +W E+ +L +L L A + + +D A + V K
Sbjct: 276 SLLQSAWMEILILGVVYRSLSFEDE--LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKY 333
Query: 293 GRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGR 352
++++ E+ LKAIAL D+ + D V+ LQ+ AL +Y Q+ P+R G+
Sbjct: 334 KSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGK 393
Query: 353 LLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDML 390
+L+ LP LR + + ++L GK P+ L +ML
Sbjct: 394 MLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEML 431
>gi|45545433 estrogen-related receptor gamma isoform 1 [Homo
sapiens]
Length = 458
Score = 180 bits (457), Expect = 2e-45
Identities = 106/338 (31%), Positives = 168/338 (49%), Gaps = 14/338 (4%)
Query: 56 CVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKK 115
C+VCGD +SG HYGV +CE CK+FFKR+I+ N+ Y+C + +C+I + R CQ CR K
Sbjct: 128 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 187
Query: 116 CFRVGMRKEAVQRGRI---PHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQ 172
C +VGM KE V+ R+ + A + L A +P +++++
Sbjct: 188 CLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAK-------KPYNKIVSH 240
Query: 173 LLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQV 232
LL AEP A + + +C+LA R L + WA+H P F L +ADQ+
Sbjct: 241 LLVAEPEKIYA--MPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQM 298
Query: 233 ALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKL 292
+LL+ +W E+ +L +L L A + + +D A + V K
Sbjct: 299 SLLQSAWMEILILGVVYRSLSFEDE--LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKY 356
Query: 293 GRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGR 352
++++ E+ LKAIAL D+ + D V+ LQ+ AL +Y Q+ P+R G+
Sbjct: 357 KSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGK 416
Query: 353 LLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDML 390
+L+ LP LR + + ++L GK P+ L +ML
Sbjct: 417 MLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEML 454
>gi|197209821 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 180 bits (457), Expect = 2e-45
Identities = 106/338 (31%), Positives = 168/338 (49%), Gaps = 14/338 (4%)
Query: 56 CVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKK 115
C+VCGD +SG HYGV +CE CK+FFKR+I+ N+ Y+C + +C+I + R CQ CR K
Sbjct: 105 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 164
Query: 116 CFRVGMRKEAVQRGRI---PHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQ 172
C +VGM KE V+ R+ + A + L A +P +++++
Sbjct: 165 CLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAK-------KPYNKIVSH 217
Query: 173 LLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVADQV 232
LL AEP A + + +C+LA R L + WA+H P F L +ADQ+
Sbjct: 218 LLVAEPEKIYA--MPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQM 275
Query: 233 ALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKL 292
+LL+ +W E+ +L +L L A + + +D A + V K
Sbjct: 276 SLLQSAWMEILILGVVYRSLSFEDE--LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKY 333
Query: 293 GRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGR 352
++++ E+ LKAIAL D+ + D V+ LQ+ AL +Y Q+ P+R G+
Sbjct: 334 KSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGK 393
Query: 353 LLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDML 390
+L+ LP LR + + ++L GK P+ L +ML
Sbjct: 394 MLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEML 431
>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 176 bits (447), Expect = 3e-44
Identities = 134/402 (33%), Positives = 195/402 (48%), Gaps = 37/402 (9%)
Query: 6 GGWGGPGGDTNGVDK--AGGY----PRAAEDDSASPPGAASDAEPGDEERPGLQVDCVVC 59
GG PG T + GY P E S+S + P P + C VC
Sbjct: 33 GGLSPPGALTTLQHQLPVSGYSTPSPATIETQSSSSEEIVP-SPPSPPPLPRIYKPCFVC 91
Query: 60 GDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRV 119
DKSSG HYGV CEGCK FF+RSI++N+ YTC +++C I++ RN+CQYCRL+KCF V
Sbjct: 92 QDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEV 151
Query: 120 GMRKEAVQ--RGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQLLRA- 176
GM KE+V+ R + +P + S + L P V ELI ++ +A
Sbjct: 152 GMSKESVRNDRNKKKKEVPKPECSESYT--------------LTP--EVGELIEKVRKAH 195
Query: 177 -EPYPAAA--GRFGAGGGAAGAV-LGID---NVCELAARLLFSTVEWARHAPFFPELPVA 229
E +PA G++ + V L ID EL+ + + TVE+A+ P F L +A
Sbjct: 196 QETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIA 255
Query: 230 DQVALLRLSWSELFVLNAAQAALPLH-TAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQ 288
DQ+ LL+ + ++ +L P T L+ M D V AF Q
Sbjct: 256 DQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQ 315
Query: 289 VDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQ 348
L L++D AE G L AI L D L P V+ LQE AL YVR + PS+P
Sbjct: 316 ---LLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPH 372
Query: 349 RFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDML 390
F ++L+++ LR++ A ++ +++ + LI++ML
Sbjct: 373 MFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEML 414
>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 176 bits (447), Expect = 3e-44
Identities = 134/402 (33%), Positives = 195/402 (48%), Gaps = 37/402 (9%)
Query: 6 GGWGGPGGDTNGVDK--AGGY----PRAAEDDSASPPGAASDAEPGDEERPGLQVDCVVC 59
GG PG T + GY P E S+S + P P + C VC
Sbjct: 33 GGLSPPGALTTLQHQLPVSGYSTPSPATIETQSSSSEEIVP-SPPSPPPLPRIYKPCFVC 91
Query: 60 GDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRV 119
DKSSG HYGV CEGCK FF+RSI++N+ YTC +++C I++ RN+CQYCRL+KCF V
Sbjct: 92 QDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEV 151
Query: 120 GMRKEAVQ--RGRIPHSLPGAVAASSGSPPGSALAAVASGGDLFPGQPVSELIAQLLRA- 176
GM KE+V+ R + +P + S + L P V ELI ++ +A
Sbjct: 152 GMSKESVRNDRNKKKKEVPKPECSESYT--------------LTP--EVGELIEKVRKAH 195
Query: 177 -EPYPAAA--GRFGAGGGAAGAV-LGID---NVCELAARLLFSTVEWARHAPFFPELPVA 229
E +PA G++ + V L ID EL+ + + TVE+A+ P F L +A
Sbjct: 196 QETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIA 255
Query: 230 DQVALLRLSWSELFVLNAAQAALPLH-TAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQ 288
DQ+ LL+ + ++ +L P T L+ M D V AF Q
Sbjct: 256 DQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQ 315
Query: 289 VDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQ 348
L L++D AE G L AI L D L P V+ LQE AL YVR + PS+P
Sbjct: 316 ---LLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPH 372
Query: 349 RFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDML 390
F ++L+++ LR++ A ++ +++ + LI++ML
Sbjct: 373 MFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEML 414
>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
Length = 457
Score = 176 bits (446), Expect = 3e-44
Identities = 123/358 (34%), Positives = 181/358 (50%), Gaps = 30/358 (8%)
Query: 44 PGDEERPGLQVDCVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQH 103
P P + C VC DKSSG HYGV CEGCK FF+RSI++N+ YTC +++C I++
Sbjct: 71 PSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKV 130
Query: 104 HRNQCQYCRLKKCFRVGMRKEAVQ--RGRIPHSLPGAVAASSGSPPGSALAAVASGGDLF 161
RN+CQYCRL+KCF VGM KE+V+ R + +P + S + L
Sbjct: 131 TRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKEVPKPECSESYT--------------LT 176
Query: 162 PGQPVSELIAQLLRA--EPYPAAA--GRFGAGGGAAGAV-LGID---NVCELAARLLFST 213
P V ELI ++ +A E +PA G++ + V L ID EL+ + + T
Sbjct: 177 P--EVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRVSLDIDLWDKFSELSTKCIIKT 234
Query: 214 VEWARHAPFFPELPVADQVALLRLSWSELFVLNAAQAALPLH-TAPLLAAAGLHAAPMAA 272
VE+A+ P F L +ADQ+ LL+ + ++ +L P T L+ M
Sbjct: 235 VEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHN 294
Query: 273 ERAVAFMDQVRAFQEQVDKLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQ 332
D V AF Q L L++D AE G L AI L D L P V+ LQE
Sbjct: 295 AGFGPLTDLVFAFANQ---LLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLL 351
Query: 333 VALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDML 390
AL YVR + PS+P F ++L+++ LR++ A ++ +++ + LI++ML
Sbjct: 352 EALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEML 409
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,258,125
Number of Sequences: 37866
Number of extensions: 871271
Number of successful extensions: 4648
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 121
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 4211
Number of HSP's gapped (non-prelim): 337
length of query: 404
length of database: 18,247,518
effective HSP length: 105
effective length of query: 299
effective length of database: 14,271,588
effective search space: 4267204812
effective search space used: 4267204812
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.