Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 20070166
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20070166 potassium voltage-gated channel, subfamily F,
member 1 [Homo sapiens]
(494 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20070166 potassium voltage-gated channel, subfamily F, member... 998 0.0
gi|4826784 potassium voltage-gated channel, Shab-related subfami... 366 e-101
gi|27436974 potassium voltage-gated channel, Shab-related subfam... 360 2e-99
gi|45383011 potassium voltage-gated channel, delayed-rectifier, ... 307 2e-83
gi|25952108 potassium voltage-gated channel delayed-rectifier pr... 296 4e-80
gi|19424136 potassium channel, subfamily V, member 2 [Homo sapiens] 284 1e-76
gi|27436988 potassium voltage-gated channel, subfamily G, member... 273 3e-73
gi|13492973 potassium voltage-gated channel delayed-rectifier pr... 273 3e-73
gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens] 269 5e-72
gi|27436996 potassium voltage-gated channel, subfamily G, member... 268 1e-71
gi|21217561 Shaw-related voltage-gated potassium channel protein... 251 1e-66
gi|21217563 Shaw-related voltage-gated potassium channel protein... 251 1e-66
gi|24497458 Shaw-related voltage-gated potassium channel protein... 251 1e-66
gi|24497460 Shaw-related voltage-gated potassium channel protein... 249 5e-66
gi|4826786 Shaw-related voltage-gated potassium channel protein ... 245 6e-65
gi|163792201 Shaw-related voltage-gated potassium channel protei... 245 6e-65
gi|6912444 potassium voltage-gated channel, subfamily G, member ... 244 1e-64
gi|27436993 potassium voltage-gated channel, subfamily G, member... 243 3e-64
gi|9789987 potassium voltage-gated channel, Shal-related subfami... 243 4e-64
gi|19071574 potassium voltage-gated channel, subfamily G, member... 239 4e-63
gi|88758576 Shaw-related voltage-gated potassium channel protein... 236 3e-62
gi|24497462 Shaw-related voltage-gated potassium channel protein... 236 3e-62
gi|24497464 Shaw-related voltage-gated potassium channel protein... 236 3e-62
gi|88758565 potassium voltage-gated channel, shaker-related subf... 234 1e-61
gi|119395748 potassium voltage-gated channel subfamily A member ... 234 2e-61
gi|27436981 potassium voltage-gated channel, Shal-related subfam... 233 3e-61
gi|27436984 potassium voltage-gated channel, Shal-related subfam... 231 1e-60
gi|27436986 potassium voltage-gated channel, Shal-related subfam... 231 1e-60
gi|4826782 potassium voltage-gated channel, shaker-related subfa... 230 2e-60
gi|4504817 potassium voltage-gated channel, shaker-related subfa... 228 1e-59
>gi|20070166 potassium voltage-gated channel, subfamily F, member 1
[Homo sapiens]
Length = 494
Score = 998 bits (2579), Expect = 0.0
Identities = 494/494 (100%), Positives = 494/494 (100%)
Query: 1 MDGSGERSLPEPGSQSSAASDDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGY 60
MDGSGERSLPEPGSQSSAASDDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGY
Sbjct: 1 MDGSGERSLPEPGSQSSAASDDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGY 60
Query: 61 DTIFSLCDDYDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDL 120
DTIFSLCDDYDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDL
Sbjct: 61 DTIFSLCDDYDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDL 120
Query: 121 KFLDDCCKSHLSEKREELEEIARRVQLILDDLGVDAAEGRWRRCQKCVWKFLEKPESSCP 180
KFLDDCCKSHLSEKREELEEIARRVQLILDDLGVDAAEGRWRRCQKCVWKFLEKPESSCP
Sbjct: 121 KFLDDCCKSHLSEKREELEEIARRVQLILDDLGVDAAEGRWRRCQKCVWKFLEKPESSCP 180
Query: 181 ARVVAVLSFLLILVSSVVMCMGTIPELQVLDAEGNRVEHPTLENVETACIGWFTLEYLLR 240
ARVVAVLSFLLILVSSVVMCMGTIPELQVLDAEGNRVEHPTLENVETACIGWFTLEYLLR
Sbjct: 181 ARVVAVLSFLLILVSSVVMCMGTIPELQVLDAEGNRVEHPTLENVETACIGWFTLEYLLR 240
Query: 241 LFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIARI 300
LFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIARI
Sbjct: 241 LFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIARI 300
Query: 301 FKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQS 360
FKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQS
Sbjct: 301 FKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQS 360
Query: 361 FWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNKQRVLE 420
FWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNKQRVLE
Sbjct: 361 FWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNKQRVLE 420
Query: 421 TAAKHELELMELNSSSGGEGKTGGSRSDLDNLPPEPAGKEAPSCSSRLKLSHSDTFIPLL 480
TAAKHELELMELNSSSGGEGKTGGSRSDLDNLPPEPAGKEAPSCSSRLKLSHSDTFIPLL
Sbjct: 421 TAAKHELELMELNSSSGGEGKTGGSRSDLDNLPPEPAGKEAPSCSSRLKLSHSDTFIPLL 480
Query: 481 TEEKHHRTRLQSCK 494
TEEKHHRTRLQSCK
Sbjct: 481 TEEKHHRTRLQSCK 494
>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
member 1 [Homo sapiens]
Length = 858
Score = 366 bits (939), Expect = e-101
Identities = 182/429 (42%), Positives = 272/429 (63%), Gaps = 5/429 (1%)
Query: 10 PEPGSQSSAASDDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDD 69
PEP + + + +NVGG+ + L + P TRL +L +C +D++ +CDD
Sbjct: 18 PEPMEIVRSKACSRRVRLNVGGLAHEVLWRTLDRLPRTRLGKLRDC--NTHDSLLEVCDD 75
Query: 70 YDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKS 129
Y E++FDR P AF ++ Y G +HM + +C + F E+D+W +D +L+ CC++
Sbjct: 76 YSLDDNEYFFDRHPGAFTSILNFYRTGRLHMMEEMCALSFSQELDYWGIDEIYLESCCQA 135
Query: 130 HLSEKREEL-EEIARRVQLILDDLGVDAAEGRWRRCQKCVWKFLEKPESSCPARVVAVLS 188
+K+E++ EE+ R + + + G + +K +W LEKP SS A+++A++S
Sbjct: 136 RYHQKKEQMNEELKREAETLREREGEEFDNTCCAEKRKKLWDLLEKPNSSVAAKILAIIS 195
Query: 189 FLLILVSSVVMCMGTIPELQVLDAEGNRVEHPTLENVETACIGWFTLEYLLRLFSSPNKL 248
+ I++S++ + + T+PELQ LD G ++P L +VE CI WFT+EYLLR SSP K
Sbjct: 196 IMFIVLSTIALSLNTLPELQSLDEFGQSTDNPQLAHVEAVCIAWFTMEYLLRFLSSPKKW 255
Query: 249 HFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIARIFKLARHSS 308
F +N +D+LAILP+YV++ LT +++ NV++ VQ RIMRI RI KLARHS+
Sbjct: 256 KFFKGPLNAIDLLAILPYYVTIFLTESNKSVLQFQNVRRVVQIFRIMRILRILKLARHST 315
Query: 309 GLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQSFWWAIITM 368
GLQ+L + L+RS+ ELGLL+++LA+GI +FS+L + E+ +T FKSIP SFWWA ITM
Sbjct: 316 GLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEDDTKFKSIPASFWWATITM 375
Query: 369 TTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNKQRVLETAAKHE-- 426
TTVGYGDIYPKT LGK+ + + GV+ IALPI I+NNF +Y +Q+ E A K
Sbjct: 376 TTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAIKRREA 435
Query: 427 LELMELNSS 435
LE + N S
Sbjct: 436 LERAKRNGS 444
>gi|27436974 potassium voltage-gated channel, Shab-related
subfamily, member 2 [Homo sapiens]
Length = 911
Score = 360 bits (923), Expect = 2e-99
Identities = 188/457 (41%), Positives = 286/457 (62%), Gaps = 7/457 (1%)
Query: 10 PEPGSQSSAASDDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDD 69
PEP + + + +NVGG+ + L + P TRL +L +C ++++ +CDD
Sbjct: 22 PEPVDIIRSKTCSRRVKINVGGLNHEVLWRTLDRLPRTRLGKLRDC--NTHESLLEVCDD 79
Query: 70 YDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKS 129
Y+ + E++FDR P AF ++ Y G++HM + +C + F E+D+W +D +L+ CC++
Sbjct: 80 YNLNENEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFGQELDYWGIDEIYLESCCQA 139
Query: 130 HLSEKREEL-EEIARRVQLILDDLGVDAAEGRWRRCQKCVWKFLEKPESSCPARVVAVLS 188
+K+E++ EE+ R + + + G + +K +W LEKP SS A+++A++S
Sbjct: 140 RYHQKKEQMNEELRREAETMREREGEEFDNTCCPDKRKKLWDLLEKPNSSVAAKILAIVS 199
Query: 189 FLLILVSSVVMCMGTIPELQVLDAEGNRVEHPTLENVETACIGWFTLEYLLRLFSSPNKL 248
L I++S++ + + T+PELQ D G ++ L +VE CI WFT+EYLLR SSPNK
Sbjct: 200 ILFIVLSTIALSLNTLPELQETDEFGQLNDNRQLAHVEAVCIAWFTMEYLLRFLSSPNKW 259
Query: 249 HFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIARIFKLARHSS 308
F +N++D+LAILP+YV++ LT +++ NV++ VQ RIMRI RI KLARHS+
Sbjct: 260 KFFKGPLNVIDLLAILPYYVTIFLTESNKSVLQFQNVRRVVQIFRIMRILRILKLARHST 319
Query: 309 GLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQSFWWAIITM 368
GLQ+L + L+RS+ ELGLL+++LA+GI +FS+L + E+ T F SIP SFWWA ITM
Sbjct: 320 GLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEDATKFTSIPASFWWATITM 379
Query: 369 TTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNKQRVLETAAKHE-- 426
TTVGYGDIYPKT LGK+ + + GV+ IALPI I+NNF +Y +Q+ E A K
Sbjct: 380 TTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAIKRREA 439
Query: 427 LELMELNSSSGGEG-KTGGSRS-DLDNLPPEPAGKEA 461
LE + N S K +RS +L ++ E AG+ A
Sbjct: 440 LERAKRNGSIVSMNLKDAFARSMELIDVAVEKAGESA 476
>gi|45383011 potassium voltage-gated channel, delayed-rectifier,
subfamily S, member 2 [Homo sapiens]
Length = 477
Score = 307 bits (786), Expect = 2e-83
Identities = 166/425 (39%), Positives = 257/425 (60%), Gaps = 22/425 (5%)
Query: 16 SSAASDDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKR 75
S A +D EI +NVGG ++ L L ++PETRL L+ C + + I LCDDYD +R
Sbjct: 10 SEANVEDGEIRINVGGFKRRLRSHTLLRFPETRLGRLLLCHSR--EAILELCDDYDDVQR 67
Query: 76 EFYFDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKR 135
EFYFDR+P+ F V+ Y+ G++H+ +C F E+++W ++ F+D CC ++
Sbjct: 68 EFYFDRNPELFPYVLHFYHTGKLHVMAELCVFSFSQEIEYWGINEFFIDSCCSYSYHGRK 127
Query: 136 EELEEIARRVQL-------ILDDLGV---DAAE------GRWRRCQKCVWKFLEKPESSC 179
E E+ Q D++ DA++ G +RR +W L+ P S
Sbjct: 128 VEPEQEKWDEQSDQESTTSSFDEILAFYNDASKFDGQPLGNFRRQ---LWLALDNPGYSV 184
Query: 180 PARVVAVLSFLLILVSSVVMCMGTIPELQVLDAEGNRVEHPTLENVETACIGWFTLEYLL 239
+RV ++LS L+++ S + MC+ ++P+ Q+ D++GN E P E VE I WFT E +
Sbjct: 185 LSRVFSILSILVVMGSIITMCLNSLPDFQIPDSQGNPGEDPRFEIVEHFGIAWFTFELVA 244
Query: 240 RLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIAR 299
R +P+ L F + +N++D+++I+PFY++L + + L N+ + Q LR+MRI R
Sbjct: 245 RFAVAPDFLKFFKNALNLIDLMSIVPFYITLVVNLVVESTPTLANLGRVAQVLRLMRIFR 304
Query: 300 IFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQ 359
I KLARHS+GL++L LK S+KE+GLLL+YL+VGI +FS + YT+E+ E L +IP
Sbjct: 305 ILKLARHSTGLRSLGATLKYSYKEVGLLLLYLSVGISIFSVVAYTIEKEENEGL-ATIPA 363
Query: 360 SFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNKQRVL 419
+WWA ++MTTVGYGD+ P TT GKL A+ L G++ + LPI I N F +Y +Q+ L
Sbjct: 364 CWWWATVSMTTVGYGDVVPGTTAGKLTASACILAGILVVVLPITLIFNKFSHFYRRQKQL 423
Query: 420 ETAAK 424
E+A +
Sbjct: 424 ESAMR 428
>gi|25952108 potassium voltage-gated channel delayed-rectifier
protein S3 [Homo sapiens]
Length = 491
Score = 296 bits (757), Expect = 4e-80
Identities = 158/415 (38%), Positives = 247/415 (59%), Gaps = 23/415 (5%)
Query: 22 DIEIV-VNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFD 80
D E+V +NVGG +Q + L ++P TRL +L+ C + I LCDDY +E+YFD
Sbjct: 13 DEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTC--HSEEAILELCDDYSVADKEYYFD 70
Query: 81 RDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELEE 140
R+P F+ V+ YY G++H+ + +C F E+++W ++ F+D CC + E++EE E
Sbjct: 71 RNPSLFRYVLNFYYTGKLHVMEELCVFSFCQEIEYWGINELFIDSCCSNRYQERKEENHE 130
Query: 141 IARRVQLILDDLGVDAA---------------EGRWRRCQKCVWKFLEKPESSCPARVVA 185
+ D+ D++ R+ + +K +W +E P A+++A
Sbjct: 131 --KDWDQKSHDVSTDSSFEESSLFEKELEKFDTLRFGQLRKKIWIRMENPAYCLSAKLIA 188
Query: 186 VLSFLLILVSSVVMCMGTIPELQVLDAEGNRVEHPTLENVETACIGWFTLEYLLRLFSSP 245
+ S ++L S V MC+ ++ E Q D E V+ P LE VE ACI WFT E +RL ++P
Sbjct: 189 ISSLSVVLASIVAMCVHSMSEFQNEDGE---VDDPVLEGVEIACIAWFTGELAVRLAAAP 245
Query: 246 NKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIARIFKLAR 305
+ F + +NI+D ++I+PFY +L + ++ N+ + VQ LR+MRI RI KLAR
Sbjct: 246 CQKKFWKNPLNIIDFVSIIPFYATLAVDTKEEESEDIENMGKVVQILRLMRIFRILKLAR 305
Query: 306 HSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQSFWWAI 365
HS GL++L L+ S+ E+GLLL++L+VGI +FS L Y++E+ + SIP +WWA
Sbjct: 306 HSVGLRSLGATLRHSYHEVGLLLLFLSVGISIFSVLIYSVEKDDHTSSLTSIPICWWWAT 365
Query: 366 ITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNKQRVLE 420
I+MTTVGYGD +P T GKL A+ +CG++ +ALPI I N F +YY KQ+ ++
Sbjct: 366 ISMTTVGYGDTHPVTLAGKLIASTCIICGILVVALPITIIFNKFSKYYQKQKDID 420
>gi|19424136 potassium channel, subfamily V, member 2 [Homo sapiens]
Length = 545
Score = 284 bits (726), Expect = 1e-76
Identities = 162/432 (37%), Positives = 245/432 (56%), Gaps = 17/432 (3%)
Query: 4 SGERSLPEPGSQSSAASDDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTI 63
+GE + +P S + + VNVGG L L+ +P+TRL L +
Sbjct: 78 AGEVTTAKPEGPSDPPALLSTLNVNVGGHSYQLDYCELAGFPKTRLGRLATSTSRSRQ-- 135
Query: 64 FSLCDDYDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFL 123
SLCDDY+ E++FDRDP F+ V Y G + + G+CP F E+ +W V LK+
Sbjct: 136 LSLCDDYEEQTDEYFFDRDPAVFQLVYNFYLSGVLLVLDGLCPRRFLEELGYWGVRLKYT 195
Query: 124 DDCCKSHLSEKREELEEIARRVQLILDDLGVDAAEGRWRRCQ------KCVWKFLEKPES 177
CC+ E+R+EL E + + V+ AE +R + + +W +EKP S
Sbjct: 196 PRCCRICFEERRDELSERLKIQHELRAQAQVEEAEELFRDMRFYGPQRRRLWNLMEKPFS 255
Query: 178 SCPARVVAVLSFLLILVSSVVMCMGTIPELQVLDA--EGNRVEHPTLENVETACIGWFTL 235
S A+ + V S +LVS V + + T+ E+Q EG P LE+VE C+G+FTL
Sbjct: 256 SVAAKAIGVASSTFVLVSVVALALNTVEEMQQHSGQGEGGPDLRPILEHVEMLCMGFFTL 315
Query: 236 EYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLT-------HLGARMMELTNVQQA 288
EYLLRL S+P+ FA S +N+VD++AILP Y+ L L G + + V Q
Sbjct: 316 EYLLRLASTPDLRRFARSALNLVDLVAILPLYLQLLLECFTGEGHQRGQTVGSVGKVGQV 375
Query: 289 VQALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQS 348
++ +R+MRI RI KLARHS+GL+ + L++ ++++G LL+++A+GIF FSA Y++E
Sbjct: 376 LRVMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLLLFIAMGIFTFSAAVYSVEHD 435
Query: 349 HPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINN 408
P T F +IP S+WWA ++++TVGYGD+YP+T LG+ A + G+I +PI + N
Sbjct: 436 VPSTNFTTIPHSWWWAAVSISTVGYGDMYPETHLGRFFAFLCIAFGIILNGMPISILYNK 495
Query: 409 FVRYYNKQRVLE 420
F YY+K + E
Sbjct: 496 FSDYYSKLKAYE 507
>gi|27436988 potassium voltage-gated channel, subfamily G, member 1
[Homo sapiens]
Length = 513
Score = 273 bits (698), Expect = 3e-73
Identities = 159/446 (35%), Positives = 255/446 (57%), Gaps = 24/446 (5%)
Query: 25 IVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFDRDPD 84
I++NVGG++ L L ++P TRL +L C +D I ++CDDYD EF+FDR+P
Sbjct: 65 IIINVGGIKYSLPWTTLDEFPLTRLGQLKACT--NFDDILNVCDDYDVTCNEFFFDRNPG 122
Query: 85 AFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELEEIARR 144
AF ++ G++ + + +C + F+ E+ +W + LD CCK +K EE E+ R
Sbjct: 123 AFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMVER 182
Query: 145 VQL--ILDDLGVDA-----AEGRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSV 197
+ LD G D+ EGR RC + + +E+P S P +V A LS L + V++V
Sbjct: 183 EEEDDALDSEGRDSEGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVTAV 242
Query: 198 VMCMGTIPELQVLDAEGNRVEH-PTLENVETACIGWFTLEYLLRLFSSPNKLHFALSFMN 256
+ + T+P L+ + +G+ + + VE+ C+GWF+LE+LLRL +P+K F S +
Sbjct: 243 NLSVSTLPSLREEEEQGHCSQMCHNVFIVESVCVGWFSLEFLLRLIQAPSKFAFLRSPLT 302
Query: 257 IVDVLAILPFYVSLTLTHL-------GARMMELTNVQQAVQALRIMRIARIFKLARHSSG 309
++D++AILP+Y++L + GA L V ++ LR +RI + +LARHS G
Sbjct: 303 LIDLVAILPYYITLLVDGAAAGRRKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHSLG 362
Query: 310 LQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPET-LFKSIPQSFWWAIITM 368
LQTL +R +E GLLL++L V I +F+ L Y +E ++ F SIP +WWA+ITM
Sbjct: 363 LQTLGLTARRCTREFGLLLLFLCVAIALFAPLLYVIENEMADSPEFTSIPACYWWAVITM 422
Query: 369 TTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYY-----NKQRVLETAA 423
TTVGYGD+ P++T G++ A S L G++ +A P+ I + F R Y ++RV+ A
Sbjct: 423 TTVGYGDMVPRSTPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKQEQERVMFRRA 482
Query: 424 KHELEL-MELNSSSGGEGKTGGSRSD 448
+ ++ +L+ S + G + SD
Sbjct: 483 QFLIKTKSQLSVSQDSDILFGSASSD 508
>gi|13492973 potassium voltage-gated channel delayed-rectifier
protein S1 [Homo sapiens]
Length = 526
Score = 273 bits (697), Expect = 3e-73
Identities = 169/493 (34%), Positives = 256/493 (51%), Gaps = 52/493 (10%)
Query: 10 PEPGSQSSAASDDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDD 69
P P + D + VNVGGVR+ L L+++P TRL L A + LCDD
Sbjct: 37 PGPDTGIRWRRSDEALRVNVGGVRRQLSARALARFPGTRLGRLQ--AAASEEQARRLCDD 94
Query: 70 YDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKS 129
YD REFYFDR P F ++ Y G +H+ +C F E D+W + L CC++
Sbjct: 95 YDEAAREFYFDRHPGFFLSLLHFYRTGHLHVLDELCVFAFGQEADYWGLGENALAACCRA 154
Query: 130 HLSEKR-------EELEEIARRVQLILDDLGVDAAE------GRWRRCQKCVWKFLEKPE 176
E+R +E + V D++ E R R ++ +W +E P
Sbjct: 155 RYLERRLTQPHAWDEDSDTPSSVDPCPDEISDVQRELARYGAARCGRLRRRLWLTMENPG 214
Query: 177 SSCPARVVAVLSFLLILVSSVVMCMGTIPELQVLDA-------------EGNRVEHPTLE 223
S P+++ + +S ++L S MC+ ++PE Q +A EG R + P L
Sbjct: 215 YSLPSKLFSCVSISVVLASIAAMCIHSLPEYQAREAAAAVAAVAAGRSPEGVR-DDPVLR 273
Query: 224 NVETACIGWFTLEYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSL----TLTHLGARM 279
+E CI WF+ E RL +P+ +F +N++D++++LPFY++L L G +
Sbjct: 274 RLEYFCIAWFSFEVSSRLLLAPSTRNFFCHPLNLIDIVSVLPFYLTLLAGVALGDQGGK- 332
Query: 280 MELTNVQQAVQALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFS 339
E ++ + VQ R+MRI R+ KLARHS+GL++L LK S++E+G+LL+YLAVG+ VFS
Sbjct: 333 -EFGHLGKVVQVFRLMRIFRVLKLARHSTGLRSLGATLKHSYREVGILLLYLAVGVSVFS 391
Query: 340 ALGYTMEQSHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIA 399
+ YT E+ + F +IP +WW ++MTTVGYGD+ P T GKL A+ L G++ +A
Sbjct: 392 GVAYTAEKEE-DVGFNTIPACWWWGTVSMTTVGYGDVVPVTVAGKLAASGCILGGILVVA 450
Query: 400 LPIHPIINNFVRYYNKQRVLETAAK--HELELMELNSSSGG--------------EGKTG 443
LPI I N F +Y +Q+ LE A + + E +L SS G EG++
Sbjct: 451 LPITIIFNKFSHFYRRQKALEAAVRNSNHQEFEDLLSSIDGVSEASLETSRETSQEGQSA 510
Query: 444 GSRSDLDNLPPEP 456
S + PP P
Sbjct: 511 DLESQAPSEPPHP 523
>gi|7657289 potassium channel, subfamily V, member 1 [Homo sapiens]
Length = 500
Score = 269 bits (687), Expect = 5e-72
Identities = 153/423 (36%), Positives = 236/423 (55%), Gaps = 22/423 (5%)
Query: 27 VNVGGVRQVLYGDLLSQYPETRLAELINCLAG--------GYDTIFSLCDDYDPGKREFY 78
VNVGG R VL LS +P TRL +L +A + LCDD +P E++
Sbjct: 43 VNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYF 102
Query: 79 FDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREEL 138
FDR AF+ V+ Y G +H+ + +C + F E+ +W +D +D CC+ ++E
Sbjct: 103 FDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELS 162
Query: 139 EEIARRV----QLILDDLGVDAAEGRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILV 194
E + + Q + D ++G ++ +W LEKP SS AR+ V+S + ++V
Sbjct: 163 ETLDFKKDTEDQESQHESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVV 222
Query: 195 SSVVMCMGTIPELQVLDAEGNRVEHPTLENVETACIGWFTLEYLLRLFSSPNKLHFALSF 254
S + M + + AE + ++ LE +E CI WFT E++LR ++ F
Sbjct: 223 SIINMAL--------MSAELSWLDLQLLEILEYVCISWFTGEFVLRFLCVRDRCRFLRKV 274
Query: 255 MNIVDVLAILPFYVSLTLTHLGARM--MELTNVQQAVQALRIMRIARIFKLARHSSGLQT 312
NI+D+LAILPFY++L + L EL NV + VQ LR++R R+ KL RHS+GL++
Sbjct: 275 PNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRS 334
Query: 313 LTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQSFWWAIITMTTVG 372
L + + ++E+GLLL++L+VGI +FS + Y EQS P+T F S+P ++WWA +MTTVG
Sbjct: 335 LGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWWWATTSMTTVG 394
Query: 373 YGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNKQRVLETAAKHELELMEL 432
YGDI P TT GK+ A + L G++ +ALPI I + F Y ++ E A + L +L
Sbjct: 395 YGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKKL 454
Query: 433 NSS 435
+
Sbjct: 455 TKN 457
>gi|27436996 potassium voltage-gated channel, subfamily G, member 4
[Homo sapiens]
Length = 519
Score = 268 bits (684), Expect = 1e-71
Identities = 155/423 (36%), Positives = 239/423 (56%), Gaps = 26/423 (6%)
Query: 24 EIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFDRDP 83
EI++NVGG R +L L ++P +RL++L C + Y+ I LCDDYD +EF+FDR P
Sbjct: 60 EILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRS--YEEIVQLCDDYDEDSQEFFFDRSP 117
Query: 84 DAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELEEIAR 143
AF ++ G++ + + +C + F+ E+ +W ++ L+ CC L K EELEE+A+
Sbjct: 118 SAFGVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLLRKLEELEELAK 177
Query: 144 RVQLILDDLGVDAAE--------GRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVS 195
L +D+ E RW C + + +E P+S P +V A LS L + +
Sbjct: 178 ---LHREDVLRQQRETRRPASHSSRWGLCMNRLREMVENPQSGLPGKVFACLSILFVATT 234
Query: 196 SVVMCMGTIPELQVLDAEGN-RVEHPTLENVETACIGWFTLEYLLRLFSSPNKLHFALSF 254
+V +C+ T+P+L+ + +G + + VET C+ WF+LE+ LR + +K F
Sbjct: 235 AVSLCVSTMPDLRAEEDQGECSRKCYYIFIVETICVAWFSLEFCLRFVQAQDKCQFFQGP 294
Query: 255 MNIVDVLAILPFYVSLTLTHLGARMME-------LTNVQQAVQALRIMRIARIFKLARHS 307
+NI+D+LAI P+YVSL ++ E L V ++ LR +RI + +LARHS
Sbjct: 295 LNIIDILAISPYYVSLAVSEEPPEDGERPSGSSYLEKVGLVLRVLRALRILYVMRLARHS 354
Query: 308 SGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETL-FKSIPQSFWWAII 366
GLQTL ++R +E GLLL++LAV I +FS L Y E+ L F SIP S+WWAII
Sbjct: 355 LGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGRVLEFTSIPASYWWAII 414
Query: 367 TMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYY----NKQRVLETA 422
+MTTVGYGD+ P++ G++ A S L G++ +A P I + F Y +Q L+
Sbjct: 415 SMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKKEQEQLQAR 474
Query: 423 AKH 425
+H
Sbjct: 475 LRH 477
>gi|21217561 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2a [Homo sapiens]
Length = 613
Score = 251 bits (641), Expect = 1e-66
Identities = 163/489 (33%), Positives = 234/489 (47%), Gaps = 90/489 (18%)
Query: 25 IVVNVGGVRQVLYGDLLSQYPETRLAELIN------------------------------ 54
+++NVGG R Y L P TRLA L +
Sbjct: 10 VILNVGGTRHETYRSTLKTLPGTRLALLASSEPPGDCLTTAGDKLQPSPPPLSPPPRAPP 69
Query: 55 -------CLAGGYDTIFSL---CDDYDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGI 104
C GG S D+ G REF+FDR P F V+ Y G++H +
Sbjct: 70 LSPGPGGCFEGGAGNCSSRGGRASDHPGGGREFFFDRHPGVFAYVLNYYRTGKLHCPADV 129
Query: 105 CPICFKNEMDFWKVDLKFLDDCCKSHLSEKR--EELEEIARRVQLILDD----------- 151
C F+ E+ FW +D ++ CC + R EE +I LI D
Sbjct: 130 CGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAAKR 189
Query: 152 LGV---------DAAEGRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSVVMCMG 202
LG+ D GRWRR Q +W E P SS AR +A S ILVS C+
Sbjct: 190 LGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLE 249
Query: 203 TIPELQVLDAEGNRVEH-------------PTLENVETACIGWFTLEYLLRLFSSPNKLH 249
T ++ + V + P L VE C+ WFT E+L+R+ SPNKL
Sbjct: 250 THEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLE 309
Query: 250 FALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIARIFKLARHSSG 309
F + +NI+D +AILPFY+ + L+ L ++ + +V ++ +R +RI RIFKL RH G
Sbjct: 310 FIKNLLNIIDFVAILPFYLEVGLSGLSSKAAK--DVLGFLRVVRFVRILRIFKLTRHFVG 367
Query: 310 LQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQ---------SHPETLFKSIPQS 360
L+ L + L+ S E LL+++LA+G+ +F+ + Y E+ + T FK+IP
Sbjct: 368 LRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIG 427
Query: 361 FWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYN----KQ 416
FWWA++TMTT+GYGD+YP+T G L A+ L GV+ IA+P+ I+NNF YY+ KQ
Sbjct: 428 FWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQ 487
Query: 417 RVLETAAKH 425
++ KH
Sbjct: 488 KLPRKRKKH 496
>gi|21217563 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2b [Homo sapiens]
Length = 638
Score = 251 bits (641), Expect = 1e-66
Identities = 163/489 (33%), Positives = 234/489 (47%), Gaps = 90/489 (18%)
Query: 25 IVVNVGGVRQVLYGDLLSQYPETRLAELIN------------------------------ 54
+++NVGG R Y L P TRLA L +
Sbjct: 10 VILNVGGTRHETYRSTLKTLPGTRLALLASSEPPGDCLTTAGDKLQPSPPPLSPPPRAPP 69
Query: 55 -------CLAGGYDTIFSL---CDDYDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGI 104
C GG S D+ G REF+FDR P F V+ Y G++H +
Sbjct: 70 LSPGPGGCFEGGAGNCSSRGGRASDHPGGGREFFFDRHPGVFAYVLNYYRTGKLHCPADV 129
Query: 105 CPICFKNEMDFWKVDLKFLDDCCKSHLSEKR--EELEEIARRVQLILDD----------- 151
C F+ E+ FW +D ++ CC + R EE +I LI D
Sbjct: 130 CGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAAKR 189
Query: 152 LGV---------DAAEGRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSVVMCMG 202
LG+ D GRWRR Q +W E P SS AR +A S ILVS C+
Sbjct: 190 LGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLE 249
Query: 203 TIPELQVLDAEGNRVEH-------------PTLENVETACIGWFTLEYLLRLFSSPNKLH 249
T ++ + V + P L VE C+ WFT E+L+R+ SPNKL
Sbjct: 250 THEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLE 309
Query: 250 FALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIARIFKLARHSSG 309
F + +NI+D +AILPFY+ + L+ L ++ + +V ++ +R +RI RIFKL RH G
Sbjct: 310 FIKNLLNIIDFVAILPFYLEVGLSGLSSKAAK--DVLGFLRVVRFVRILRIFKLTRHFVG 367
Query: 310 LQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQ---------SHPETLFKSIPQS 360
L+ L + L+ S E LL+++LA+G+ +F+ + Y E+ + T FK+IP
Sbjct: 368 LRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIG 427
Query: 361 FWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYN----KQ 416
FWWA++TMTT+GYGD+YP+T G L A+ L GV+ IA+P+ I+NNF YY+ KQ
Sbjct: 428 FWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQ 487
Query: 417 RVLETAAKH 425
++ KH
Sbjct: 488 KLPRKRKKH 496
>gi|24497458 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2c [Homo sapiens]
Length = 558
Score = 251 bits (641), Expect = 1e-66
Identities = 163/489 (33%), Positives = 234/489 (47%), Gaps = 90/489 (18%)
Query: 25 IVVNVGGVRQVLYGDLLSQYPETRLAELIN------------------------------ 54
+++NVGG R Y L P TRLA L +
Sbjct: 10 VILNVGGTRHETYRSTLKTLPGTRLALLASSEPPGDCLTTAGDKLQPSPPPLSPPPRAPP 69
Query: 55 -------CLAGGYDTIFSL---CDDYDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGI 104
C GG S D+ G REF+FDR P F V+ Y G++H +
Sbjct: 70 LSPGPGGCFEGGAGNCSSRGGRASDHPGGGREFFFDRHPGVFAYVLNYYRTGKLHCPADV 129
Query: 105 CPICFKNEMDFWKVDLKFLDDCCKSHLSEKR--EELEEIARRVQLILDD----------- 151
C F+ E+ FW +D ++ CC + R EE +I LI D
Sbjct: 130 CGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAAKR 189
Query: 152 LGV---------DAAEGRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSVVMCMG 202
LG+ D GRWRR Q +W E P SS AR +A S ILVS C+
Sbjct: 190 LGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLE 249
Query: 203 TIPELQVLDAEGNRVEH-------------PTLENVETACIGWFTLEYLLRLFSSPNKLH 249
T ++ + V + P L VE C+ WFT E+L+R+ SPNKL
Sbjct: 250 THEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLE 309
Query: 250 FALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIARIFKLARHSSG 309
F + +NI+D +AILPFY+ + L+ L ++ + +V ++ +R +RI RIFKL RH G
Sbjct: 310 FIKNLLNIIDFVAILPFYLEVGLSGLSSKAAK--DVLGFLRVVRFVRILRIFKLTRHFVG 367
Query: 310 LQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQ---------SHPETLFKSIPQS 360
L+ L + L+ S E LL+++LA+G+ +F+ + Y E+ + T FK+IP
Sbjct: 368 LRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIG 427
Query: 361 FWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYN----KQ 416
FWWA++TMTT+GYGD+YP+T G L A+ L GV+ IA+P+ I+NNF YY+ KQ
Sbjct: 428 FWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQ 487
Query: 417 RVLETAAKH 425
++ KH
Sbjct: 488 KLPRKRKKH 496
>gi|24497460 Shaw-related voltage-gated potassium channel protein 3
[Homo sapiens]
Length = 757
Score = 249 bits (635), Expect = 5e-66
Identities = 169/494 (34%), Positives = 236/494 (47%), Gaps = 90/494 (18%)
Query: 13 GSQSSAASDDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDP 72
G D +IV+NVGGVR Y L P TRLA L A DYDP
Sbjct: 78 GRHGGGGGDSGKIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARF-------DYDP 130
Query: 73 GKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLS 132
G EF+FDR P F V+ Y G++H +C F+ E+ FW +D ++ CC
Sbjct: 131 GADEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYR 190
Query: 133 EKREELEEI-----------------ARRVQLILDDL------GVDAAEGR--------- 160
+ R+ E + A LDD G+D A G
Sbjct: 191 QHRDAEEALDSFEAPDPAGAANAANAAGAHDGGLDDEAGAGGGGLDGAGGELKRLCFQDA 250
Query: 161 ------------------WRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSVVMCMG 202
WRR Q VW E P SS AR VA S IL+S C+
Sbjct: 251 GGGAGGPPGGAGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLE 310
Query: 203 T-----------------IPELQVLDAEGNRVE-HPTLENVETACIGWFTLEYLLRLFSS 244
T IP + VE P L VE C+ WFT E+L+R+
Sbjct: 311 THEGFIHISNKTVTQASPIPGAPPENITNVEVETEPFLTYVEGVCVVWFTFEFLMRITFC 370
Query: 245 PNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIARIFKLA 304
P+K+ F S +NI+D +AILPFY+ + L+ L ++ + +V ++ +R +RI RIFKL
Sbjct: 371 PDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAAK--DVLGFLRVVRFVRILRIFKLT 428
Query: 305 RHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQ--SHPE-------TLFK 355
RH GL+ L + L+ S E LL+++LA+G+ +F+ + Y E+ + P+ T FK
Sbjct: 429 RHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFK 488
Query: 356 SIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYN- 414
+IP FWWA++TMTT+GYGD+YPKT G L A+ L GV+ IA+P+ I+NNF YY+
Sbjct: 489 NIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSL 548
Query: 415 ---KQRVLETAAKH 425
KQ++ + KH
Sbjct: 549 AMAKQKLPKKKNKH 562
>gi|4826786 Shaw-related voltage-gated potassium channel protein 1
isoform B [Homo sapiens]
Length = 511
Score = 245 bits (626), Expect = 6e-65
Identities = 156/459 (33%), Positives = 226/459 (49%), Gaps = 67/459 (14%)
Query: 25 IVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFDRDPD 84
IV+NVGG R Y L P TRLA L A + DYDP EF+FDR P
Sbjct: 10 IVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHF-------DYDPRADEFFFDRHPG 62
Query: 85 AFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELE----- 139
F ++ Y G++H +C ++ E+ FW +D ++ CC + R+ E
Sbjct: 63 VFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSF 122
Query: 140 -------------------------EIARRVQLILDDLGVDAAEGRWRRCQKCVWKFLEK 174
E+ +L L D G WRR Q +W E
Sbjct: 123 GGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFED 182
Query: 175 PESSCPARVVAVLSFLLILVSSVVMCMGTIPELQ--VLDAEGNRVEHPT----------- 221
P SS AR VA S ILVS C+ T V E V + T
Sbjct: 183 PYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETE 242
Query: 222 --LENVETACIGWFTLEYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARM 279
L +E C+ WFT E+L+R+ PNK+ F + +NI+D +AILPFY+ + L+ L ++
Sbjct: 243 AFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKA 302
Query: 280 MELTNVQQAVQALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFS 339
+ +V ++ +R +RI RIFKL RH GL+ L + L+ S E LL+++LA+G+ +F+
Sbjct: 303 AK--DVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFA 360
Query: 340 ALGYTMEQ---------SHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAIS 390
+ Y E+ + T FK+IP FWWA++TMTT+GYGD+YP+T G L A+
Sbjct: 361 TMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALC 420
Query: 391 FLCGVIAIALPIHPIINNFVRYYN----KQRVLETAAKH 425
L GV+ IA+P+ I+NNF YY+ KQ++ + KH
Sbjct: 421 ALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKH 459
>gi|163792201 Shaw-related voltage-gated potassium channel protein 1
isoform A [Homo sapiens]
Length = 585
Score = 245 bits (626), Expect = 6e-65
Identities = 156/459 (33%), Positives = 226/459 (49%), Gaps = 67/459 (14%)
Query: 25 IVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFDRDPD 84
IV+NVGG R Y L P TRLA L A + DYDP EF+FDR P
Sbjct: 10 IVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHF-------DYDPRADEFFFDRHPG 62
Query: 85 AFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELE----- 139
F ++ Y G++H +C ++ E+ FW +D ++ CC + R+ E
Sbjct: 63 VFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSF 122
Query: 140 -------------------------EIARRVQLILDDLGVDAAEGRWRRCQKCVWKFLEK 174
E+ +L L D G WRR Q +W E
Sbjct: 123 GGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFED 182
Query: 175 PESSCPARVVAVLSFLLILVSSVVMCMGTIPELQ--VLDAEGNRVEHPT----------- 221
P SS AR VA S ILVS C+ T V E V + T
Sbjct: 183 PYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETE 242
Query: 222 --LENVETACIGWFTLEYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARM 279
L +E C+ WFT E+L+R+ PNK+ F + +NI+D +AILPFY+ + L+ L ++
Sbjct: 243 AFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKA 302
Query: 280 MELTNVQQAVQALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFS 339
+ +V ++ +R +RI RIFKL RH GL+ L + L+ S E LL+++LA+G+ +F+
Sbjct: 303 AK--DVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFA 360
Query: 340 ALGYTMEQ---------SHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAIS 390
+ Y E+ + T FK+IP FWWA++TMTT+GYGD+YP+T G L A+
Sbjct: 361 TMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALC 420
Query: 391 FLCGVIAIALPIHPIINNFVRYYN----KQRVLETAAKH 425
L GV+ IA+P+ I+NNF YY+ KQ++ + KH
Sbjct: 421 ALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKH 459
>gi|6912444 potassium voltage-gated channel, subfamily G, member 2
[Homo sapiens]
Length = 466
Score = 244 bits (624), Expect = 1e-64
Identities = 144/444 (32%), Positives = 246/444 (55%), Gaps = 16/444 (3%)
Query: 25 IVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFDRDPD 84
+++NVGG R L L++ P RL L C G+D + +CDDYD + EF+FDR P
Sbjct: 19 VIINVGGCRVRLAWAALARCPLARLERLRACR--GHDDLLRVCDDYDVSRDEFFFDRSPC 76
Query: 85 AFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELEEIARR 144
AF+ ++ + G++ + +G C + F++E+ +W +D L+ CC L + EE E AR
Sbjct: 77 AFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRREEEAAE-ARA 135
Query: 145 VQLILDDLGVDA----AEGRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSVVMC 200
G A GR +R ++ + ++ P S ++ A +S + V++V +C
Sbjct: 136 GPTERGAQGSPARALGPRGRLQRGRRRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVGLC 195
Query: 201 MGTIPELQVLDAEGN-RVEHPTLENVETACIGWFTLEYLLRLFSSPNKLHFALSFMNIVD 259
+ T+P+++ + G + +L +ET C+ WF+ E+LLR + +K F + +NI+D
Sbjct: 196 LSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQAESKCAFLRAPLNIID 255
Query: 260 VLAILPFYVSLTLTHL----GARMMELTNVQQAVQALRIMRIARIFKLARHSSGLQTLTY 315
+LA+LPFYVSL L G +++E + ++ LR +R+ + +LARHS GL++L
Sbjct: 256 ILALLPFYVSLLLGLAAGPGGTKLLERAGL--VLRLLRALRVLYVMRLARHSLGLRSLGL 313
Query: 316 ALKRSFKELGLLLMYLAVGIFVFSALGYTMEQS-HPETLFKSIPQSFWWAIITMTTVGYG 374
++R +E GLLL++L V + +F+ L + E+ F S+P S+WWA+I+MTTVGYG
Sbjct: 314 TMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYWWAVISMTTVGYG 373
Query: 375 DIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNK-QRVLETAAKHELELMELN 433
D+ P++ G++ A S L G++ +A P+ I + F R Y++ + + AA E L E +
Sbjct: 374 DMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQRAASPEPALQEDS 433
Query: 434 SSSGGEGKTGGSRSDLDNLPPEPA 457
+ S + D L + A
Sbjct: 434 THSATATEDSSQGPDSAGLADDSA 457
>gi|27436993 potassium voltage-gated channel, subfamily G, member 3
isoform 2 [Homo sapiens]
Length = 425
Score = 243 bits (620), Expect = 3e-64
Identities = 148/430 (34%), Positives = 237/430 (55%), Gaps = 20/430 (4%)
Query: 15 QSSAASDDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGK 74
+S AAS +V+NVGG R L +LL +P R++ L C + + +CDDYD +
Sbjct: 5 RSGAAS----VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSER--DVLEVCDDYDRER 58
Query: 75 REFYFDRDPDAFKCVI-EVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSE 133
E++FDR +AF ++ V G++ +C + F NEM +W ++ L+ CC+ L +
Sbjct: 59 NEYFFDRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDD 118
Query: 134 KREELEEIARRVQ---LILDDLGVDAAEGR-WRRCQKCVWKFLEKPESSCPARVVAVLSF 189
+ + + L D+ AE RR + + + E+P SS A+++A +S
Sbjct: 119 RMSDTYTFYSADEPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSV 178
Query: 190 LLILVSSVVMCMGTIPELQVLDAEGNRVEHPTLENVETACIGWFTLEYLLRLFSSPNKLH 249
+ ++VS VV+C T+P+ + A+ NR +E CIGWFT E ++R S NK
Sbjct: 179 VFVIVSMVVLCASTLPDWRNAAAD-NRSLDDRSRIIEAICIGWFTAECIVRFIVSKNKCE 237
Query: 250 FALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIARIFKLARHSSG 309
F +NI+D+LAI P+Y+S+ +T +L ++ LR+MRI + KLARH G
Sbjct: 238 FVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRIFWVIKLARHFIG 297
Query: 310 LQTLTYALKRSFKELGLLLMYLAVGIFVFSAL------GYTMEQSHPETLFKSIPQSFWW 363
LQTL LKR ++E+ +LL+++ V + +FSAL G +E S+ + F SIP + WW
Sbjct: 298 LQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKD--FTSIPAACWW 355
Query: 364 AIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNKQRVLETAA 423
II+MTTVGYGD+YP T G++ + + G++ +ALPI I ++FV+ Y++ +
Sbjct: 356 VIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELKFRSARY 415
Query: 424 KHELELMELN 433
L LN
Sbjct: 416 SRSLSTEFLN 425
>gi|9789987 potassium voltage-gated channel, Shal-related subfamily,
member 2 [Homo sapiens]
Length = 630
Score = 243 bits (619), Expect = 4e-64
Identities = 151/441 (34%), Positives = 233/441 (52%), Gaps = 39/441 (8%)
Query: 9 LPEPGSQSSAASDDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCD 68
+P P Q + D IV+NV G R + D L +YP+T L G + F
Sbjct: 27 MPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLERYPDT--------LLGSSERDFF--- 75
Query: 69 DYDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCK 128
Y P ++++FDRDPD F+ ++ Y G++H + C + E+ F+ + + + DCC
Sbjct: 76 -YHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELAFFGLIPEIIGDCCY 134
Query: 129 SHLSEKREELEEIARRVQLILDDLGVDAAEGR---WRRCQKCVWKFLEKPESSCPARVVA 185
++R E E R+Q DD D A ++ VW+ E P +S A V
Sbjct: 135 EEYKDRRRENAE---RLQ---DDADTDTAGESALPTMTARQRVWRAFENPHTSTMALVFY 188
Query: 186 VLSFLLILVSSVVMCMGTIPELQVLDAEGNRVEHPTLEN-------VETACIGWFTLEYL 238
++ I VS + + T+P + G+ E P E ++TAC+ FT+EYL
Sbjct: 189 YVTGFFIAVSVIANVVETVP---CGSSPGHIKELPCGERYAVAFFCLDTACVMIFTVEYL 245
Query: 239 LRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIA 298
LRL ++P++ F S M+I+DV+AILP+Y+ L +T + +V A LR+ R+
Sbjct: 246 LRLAAAPSRYRFVRSVMSIIDVVAILPYYIGLVMT-------DNEDVSGAFVTLRVFRVF 298
Query: 299 RIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIP 358
RIFK +RHS GL+ L Y LK ELG LL L + I +F+ + + E+ + F SIP
Sbjct: 299 RIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIP 358
Query: 359 QSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVR-YYNKQR 417
+FW+ I+TMTT+GYGD+ PKT GK+ +I L GV+ IALP+ I++NF R Y+ QR
Sbjct: 359 AAFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQR 418
Query: 418 VLETAAKHELELMELNSSSGG 438
+ A+ + L + ++ G
Sbjct: 419 ADKRRAQKKARLARIRAAKSG 439
>gi|19071574 potassium voltage-gated channel, subfamily G, member 3
isoform 1 [Homo sapiens]
Length = 436
Score = 239 bits (610), Expect = 4e-63
Identities = 146/440 (33%), Positives = 239/440 (54%), Gaps = 29/440 (6%)
Query: 15 QSSAASDDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGK 74
+S AAS +V+NVGG R L +LL +P R++ L C + + +CDDYD +
Sbjct: 5 RSGAAS----VVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSER--DVLEVCDDYDRER 58
Query: 75 REFYFDRDPDAFKCVI-EVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSE 133
E++FDR +AF ++ V G++ +C + F NEM +W ++ L+ CC+ L +
Sbjct: 59 NEYFFDRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDD 118
Query: 134 KREELEEIARRVQ---LILDDLGVDAAEGR-WRRCQKCVWKFLEKPESSCPARVVAVLSF 189
+ + + L D+ AE RR + + + E+P SS A+++A +S
Sbjct: 119 RMSDTYTFYSADEPGVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSV 178
Query: 190 LLILVSSVVMCMGTIPELQVLDAEGNRVEHPTLEN----------VETACIGWFTLEYLL 239
+ ++VS VV+C T+P+ + A+ ++ + + +E CIGWFT E ++
Sbjct: 179 VFVIVSMVVLCASTLPDWRNAAADNRSLDDRSRYSAGPGREPSGIIEAICIGWFTAECIV 238
Query: 240 RLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIAR 299
R S NK F +NI+D+LAI P+Y+S+ +T +L ++ LR+MRI
Sbjct: 239 RFIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRIFW 298
Query: 300 IFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSAL------GYTMEQSHPETL 353
+ KLARH GLQTL LKR ++E+ +LL+++ V + +FSAL G +E S+ +
Sbjct: 299 VIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKD-- 356
Query: 354 FKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYY 413
F SIP + WW II+MTTVGYGD+YP T G++ + + G++ +ALPI I ++FV+ Y
Sbjct: 357 FTSIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCY 416
Query: 414 NKQRVLETAAKHELELMELN 433
++ + L LN
Sbjct: 417 HELKFRSARYSRSLSTEFLN 436
>gi|88758576 Shaw-related voltage-gated potassium channel protein 4
isoform c [Homo sapiens]
Length = 626
Score = 236 bits (603), Expect = 3e-62
Identities = 159/470 (33%), Positives = 229/470 (48%), Gaps = 61/470 (12%)
Query: 24 EIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTI----FSLCDDYDPGKREFYF 79
+I++NVGG R Y L P TRLA L + GG G EF+F
Sbjct: 37 KIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFF 96
Query: 80 DRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELE 139
DR P F V+ Y G++H +C F+ E+ FW +D ++ CC + R+ E
Sbjct: 97 DRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEE 156
Query: 140 EIA--------------------RRVQLILDDLGVD-------AAEGRWRRCQKCVWKFL 172
+ +L L LG A G R Q +W
Sbjct: 157 ALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWALF 216
Query: 173 EKPESSCPARVVAVLSFLLILVSSVVMCMGTIPELQV------LDAEGN--------RVE 218
E P SS ARVVA S ILVS C+ T + + GN VE
Sbjct: 217 EDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRVGNITSVHFRREVE 276
Query: 219 -HPTLENVETACIGWFTLEYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGA 277
P L +E C+ WFTLE+L+R+ P+ L F + +NI+D +AILPFY+ + L+ L +
Sbjct: 277 TEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSS 336
Query: 278 RMMELTNVQQAVQALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFV 337
+ +V ++ +R +RI RIFKL RH GL+ L + L+ S E LL+++LA+G+ +
Sbjct: 337 KAAR--DVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLI 394
Query: 338 FSALGYTMEQ---------SHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAA 388
F+ + Y E+ + T FK+IP FWWA++TMTT+GYGD+YPKT G L A
Sbjct: 395 FATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGA 454
Query: 389 ISFLCGVIAIALPIHPIINNFVRYYN----KQRVLETAAKHELELMELNS 434
+ L GV+ IA+P+ I+NNF YY+ KQ++ + KH +L S
Sbjct: 455 LCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPAQLES 504
>gi|24497462 Shaw-related voltage-gated potassium channel protein 4
isoform a [Homo sapiens]
Length = 635
Score = 236 bits (603), Expect = 3e-62
Identities = 159/470 (33%), Positives = 229/470 (48%), Gaps = 61/470 (12%)
Query: 24 EIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTI----FSLCDDYDPGKREFYF 79
+I++NVGG R Y L P TRLA L + GG G EF+F
Sbjct: 37 KIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFF 96
Query: 80 DRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELE 139
DR P F V+ Y G++H +C F+ E+ FW +D ++ CC + R+ E
Sbjct: 97 DRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEE 156
Query: 140 EIA--------------------RRVQLILDDLGVD-------AAEGRWRRCQKCVWKFL 172
+ +L L LG A G R Q +W
Sbjct: 157 ALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWALF 216
Query: 173 EKPESSCPARVVAVLSFLLILVSSVVMCMGTIPELQV------LDAEGN--------RVE 218
E P SS ARVVA S ILVS C+ T + + GN VE
Sbjct: 217 EDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRVGNITSVHFRREVE 276
Query: 219 -HPTLENVETACIGWFTLEYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGA 277
P L +E C+ WFTLE+L+R+ P+ L F + +NI+D +AILPFY+ + L+ L +
Sbjct: 277 TEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSS 336
Query: 278 RMMELTNVQQAVQALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFV 337
+ +V ++ +R +RI RIFKL RH GL+ L + L+ S E LL+++LA+G+ +
Sbjct: 337 KAAR--DVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLI 394
Query: 338 FSALGYTMEQ---------SHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAA 388
F+ + Y E+ + T FK+IP FWWA++TMTT+GYGD+YPKT G L A
Sbjct: 395 FATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGA 454
Query: 389 ISFLCGVIAIALPIHPIINNFVRYYN----KQRVLETAAKHELELMELNS 434
+ L GV+ IA+P+ I+NNF YY+ KQ++ + KH +L S
Sbjct: 455 LCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPAQLES 504
>gi|24497464 Shaw-related voltage-gated potassium channel protein 4
isoform b [Homo sapiens]
Length = 582
Score = 236 bits (603), Expect = 3e-62
Identities = 159/470 (33%), Positives = 229/470 (48%), Gaps = 61/470 (12%)
Query: 24 EIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTI----FSLCDDYDPGKREFYF 79
+I++NVGG R Y L P TRLA L + GG G EF+F
Sbjct: 37 KIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFF 96
Query: 80 DRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELE 139
DR P F V+ Y G++H +C F+ E+ FW +D ++ CC + R+ E
Sbjct: 97 DRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEE 156
Query: 140 EIA--------------------RRVQLILDDLGVD-------AAEGRWRRCQKCVWKFL 172
+ +L L LG A G R Q +W
Sbjct: 157 ALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWALF 216
Query: 173 EKPESSCPARVVAVLSFLLILVSSVVMCMGTIPELQV------LDAEGN--------RVE 218
E P SS ARVVA S ILVS C+ T + + GN VE
Sbjct: 217 EDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRVGNITSVHFRREVE 276
Query: 219 -HPTLENVETACIGWFTLEYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGA 277
P L +E C+ WFTLE+L+R+ P+ L F + +NI+D +AILPFY+ + L+ L +
Sbjct: 277 TEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSS 336
Query: 278 RMMELTNVQQAVQALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFV 337
+ +V ++ +R +RI RIFKL RH GL+ L + L+ S E LL+++LA+G+ +
Sbjct: 337 KAAR--DVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLI 394
Query: 338 FSALGYTMEQ---------SHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAA 388
F+ + Y E+ + T FK+IP FWWA++TMTT+GYGD+YPKT G L A
Sbjct: 395 FATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGA 454
Query: 389 ISFLCGVIAIALPIHPIINNFVRYYN----KQRVLETAAKHELELMELNS 434
+ L GV+ IA+P+ I+NNF YY+ KQ++ + KH +L S
Sbjct: 455 LCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPAQLES 504
>gi|88758565 potassium voltage-gated channel, shaker-related
subfamily, member 3 [Homo sapiens]
Length = 575
Score = 234 bits (598), Expect = 1e-61
Identities = 162/482 (33%), Positives = 251/482 (52%), Gaps = 73/482 (15%)
Query: 3 GSGERSLPEPGSQSSAASDDI---EIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGG 59
G +R P P S +A D +V+N+ G+R L Q+PET L + +
Sbjct: 81 GGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRY- 139
Query: 60 YDTIFSLCDDYDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPI-CFKNEMDFWKV 118
+DP + E++FDR+ +F ++ Y G + PI F E+ F+++
Sbjct: 140 ----------FDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQL 189
Query: 119 DLKFLDDCCKSHLSEKREELEEIARRVQLILDDLGVDAAEGRWRRCQKCVWKFLEKPESS 178
+ + EK E E R + L R Q+ VW E PESS
Sbjct: 190 GEEAM---------EKFREDEGFLREEERPLPR----------RDFQRQVWLLFEYPESS 230
Query: 179 CPARVVAVLSFLLILVSSVVMCMGTIPELQ------------VLDAEGN-----RVEHPT 221
PAR +A++S L+IL+S V+ C+ T+PE + +A GN R +
Sbjct: 231 GPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASS 290
Query: 222 LEN----VETACIGWFTLEYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGA 277
+ VET CI WF+ E L+R F+ P+K F+ + MN++D++AI+P++++L T L
Sbjct: 291 FSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLG-TELAE 349
Query: 278 RMMELTNVQQAV-----QALRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLA 332
R N QQA+ + +R++R+ RIFKL+RHS GLQ L LK S +ELGLL+ +L
Sbjct: 350 RQ---GNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLF 406
Query: 333 VGIFVFSALGYTMEQSHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFL 392
+G+ +FS+ Y E P + F SIP +FWWA++TMTTVGYGD++P T GK+ ++ +
Sbjct: 407 IGVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAI 466
Query: 393 CGVIAIALPIHPIINNFVRYYNKQRVLETAAKHELELMELN-----SSSGGEGKTGGSRS 447
GV+ IALP+ I++NF +Y++ ET + + + M + SSS E + S S
Sbjct: 467 AGVLTIALPVPVIVSNFNYFYHR----ETEGEEQSQYMHVGSCQHLSSSAEELRKARSNS 522
Query: 448 DL 449
L
Sbjct: 523 TL 524
>gi|119395748 potassium voltage-gated channel subfamily A member 1
[Homo sapiens]
Length = 495
Score = 234 bits (596), Expect = 2e-61
Identities = 150/452 (33%), Positives = 243/452 (53%), Gaps = 65/452 (14%)
Query: 10 PEPGSQSSAAS-DDIE----IVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIF 64
P+ GS A DD E +V+N+ G+R L+Q+P T L +
Sbjct: 19 PQDGSYPRQADHDDHECCERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRY------ 72
Query: 65 SLCDDYDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLD 124
+DP + E++FDR+ +F ++ Y G + P+ D + ++KF +
Sbjct: 73 -----FDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPL------DMFSEEIKFYE 121
Query: 125 DCCKSHLSEKREELEEIARRVQLILDDLGVDAAEGRWRRCQKCVWKFLEKPESSCPARVV 184
EK E E + + L + + Q+ VW E PESS PARV+
Sbjct: 122 --LGEEAMEKFREDEGFIKEEERPLPE----------KEYQRQVWLLFEYPESSGPARVI 169
Query: 185 AVLSFLLILVSSVVMCMGTIPELQV-LDAEG--NRVEHPTLEN-----------VETACI 230
A++S ++IL+S V+ C+ T+PEL+ D G +R+++ T+ VET CI
Sbjct: 170 AIVSVMVILISIVIFCLETLPELKDDKDFTGTVHRIDNTTVIYNSNIFTDPFFIVETLCI 229
Query: 231 GWFTLEYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQ 290
WF+ E ++R F+ P+K F + MN +D++AI+P++++L G + E Q+ Q
Sbjct: 230 IWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITL-----GTEIAEQEGNQKGEQ 284
Query: 291 A--------LRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALG 342
A +R++R+ RIFKL+RHS GLQ L LK S +ELGLL+ +L +G+ +FS+
Sbjct: 285 ATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAV 344
Query: 343 YTMEQSHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPI 402
Y E E+ F SIP +FWWA+++MTTVGYGD+YP T GK+ ++ + GV+ IALP+
Sbjct: 345 YFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPV 404
Query: 403 HPIINNFVRYYNKQRVLETAAKHELELMELNS 434
I++NF +Y++ ET + + +L+ ++S
Sbjct: 405 PVIVSNFNYFYHR----ETEGEEQAQLLHVSS 432
>gi|27436981 potassium voltage-gated channel, Shal-related
subfamily, member 1 [Homo sapiens]
Length = 647
Score = 233 bits (594), Expect = 3e-61
Identities = 158/467 (33%), Positives = 238/467 (50%), Gaps = 40/467 (8%)
Query: 10 PEPGSQSSAASDDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDD 69
P PG ++S D +VVNV G R + + L +YP+T L G + F
Sbjct: 29 PAPGVKASRG--DEVLVVNVSGRRFETWKNTLDRYPDT--------LLGSSEKEFF---- 74
Query: 70 YDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKS 129
YD E++FDRDPD F+ V+ Y G +H + C F E+ F+ + + + DCC
Sbjct: 75 YDADSGEYFFDRDPDMFRHVLNFYRTGRLHCPRQECIQAFDEELAFYGLVPELVGDCC-- 132
Query: 130 HLSEKREELEEIARRVQLILDDLGVDAAEG----RWRRCQKCVWKFLEKPESSCPARVVA 185
L E R+ +E A R L D+ A +G ++ +W+ E P +S A V
Sbjct: 133 -LEEYRDRKKENAER--LAEDEEAEQAGDGPALPAGSSLRQRLWRAFENPHTSTAALVFY 189
Query: 186 VLSFLLILVSSVVMCMGTIPELQVLDAEGNRVEHPTLEN-------VETACIGWFTLEYL 238
++ I VS + + TIP A + E P E ++TAC+ FT EYL
Sbjct: 190 YVTGFFIAVSVIANVVETIPCRG--SARRSSREQPCGERFPQAFFCMDTACVLIFTGEYL 247
Query: 239 LRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIA 298
LRLF++P++ F S M+++DV+AILP+Y+ L + + +V A LR+ R+
Sbjct: 248 LRLFAAPSRCRFLRSVMSLIDVVAILPYYIGLLVP-------KNDDVSGAFVTLRVFRVF 300
Query: 299 RIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIP 358
RIFK +RHS GL+ L Y LK ELG LL L + I +F+ + + E+ +T F SIP
Sbjct: 301 RIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTNKTNFTSIP 360
Query: 359 QSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVR-YYNKQR 417
+FW+ I+TMTT+GYGD+ P T GK+ +I L GV+ IALP+ I++NF R Y+ QR
Sbjct: 361 AAFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQR 420
Query: 418 VLETAAKHELELMELNSSSGGEGKTGGSRSDLDNLPPEPAGKEAPSC 464
+ A+ ++ L + + G L +G+E C
Sbjct: 421 ADKRRAQQKVRLARIRLAKSGTTNAFLQYKQNGGLEDSGSGEEQALC 467
>gi|27436984 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 1 [Homo sapiens]
Length = 655
Score = 231 bits (589), Expect = 1e-60
Identities = 153/488 (31%), Positives = 250/488 (51%), Gaps = 46/488 (9%)
Query: 9 LPEPGSQSSAASDDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCD 68
+P + + D++ IV+NV G R + L +YP+T L G + F +
Sbjct: 27 MPLAPADKNKRQDEL-IVLNVSGRRFQTWRTTLERYPDT--------LLGSTEKEFFFNE 77
Query: 69 DYDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCK 128
D +E++FDRDP+ F+CV+ Y G++H + C + +E+ F+ + + + DCC
Sbjct: 78 D----TKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCY 133
Query: 129 SHLSEKREELEEIARRVQLILDDLGVDAAEGRWRRC--QKCVWKFLEKPESSCPARVVAV 186
+++ E + ++DD + + ++ +W+ E P +S A V
Sbjct: 134 EEYKDRKRE------NAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTSTLALVFYY 187
Query: 187 LSFLLILVSSVVMCMGTIPELQVLDAEGNRVEHPTLEN-------VETACIGWFTLEYLL 239
++ I VS + + T+P V ++ E P E ++TAC+ FT+EYLL
Sbjct: 188 VTGFFIAVSVITNVVETVPCGTVPGSK----ELPCGERYSVAFFCLDTACVMIFTVEYLL 243
Query: 240 RLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIAR 299
RLF++P++ F S M+I+DV+AI+P+Y+ L +T+ +V A LR+ R+ R
Sbjct: 244 RLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNN-------EDVSGAFVTLRVFRVFR 296
Query: 300 IFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQ 359
IFK +RHS GL+ L Y LK ELG LL L + I +F+ + + E+ + F SIP
Sbjct: 297 IFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPA 356
Query: 360 SFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVR-YYNKQRV 418
SFW+ I+TMTT+GYGD+ PKT GK+ +I L GV+ IALP+ I++NF R Y+ QR
Sbjct: 357 SFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRA 416
Query: 419 LETAAKHELELMELNSSSGGEGKTGGSRSDLDNLPPEPAGKEAPSCSSRLKLSHSDTFIP 478
+ A+ + L + + KTG S + L + EA + + H
Sbjct: 417 DKRRAQKKARLARIRVA-----KTGSSNAYLHS-KRNGLLNEALELTGTPEEEHMGKTTS 470
Query: 479 LLTEEKHH 486
L+ + HH
Sbjct: 471 LIESQHHH 478
>gi|27436986 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 2 [Homo sapiens]
Length = 636
Score = 231 bits (589), Expect = 1e-60
Identities = 153/488 (31%), Positives = 250/488 (51%), Gaps = 46/488 (9%)
Query: 9 LPEPGSQSSAASDDIEIVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCD 68
+P + + D++ IV+NV G R + L +YP+T L G + F +
Sbjct: 27 MPLAPADKNKRQDEL-IVLNVSGRRFQTWRTTLERYPDT--------LLGSTEKEFFFNE 77
Query: 69 DYDPGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCK 128
D +E++FDRDP+ F+CV+ Y G++H + C + +E+ F+ + + + DCC
Sbjct: 78 D----TKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGILPEIIGDCCY 133
Query: 129 SHLSEKREELEEIARRVQLILDDLGVDAAEGRWRRC--QKCVWKFLEKPESSCPARVVAV 186
+++ E + ++DD + + ++ +W+ E P +S A V
Sbjct: 134 EEYKDRKRE------NAERLMDDNDSENNQESMPSLSFRQTMWRAFENPHTSTLALVFYY 187
Query: 187 LSFLLILVSSVVMCMGTIPELQVLDAEGNRVEHPTLEN-------VETACIGWFTLEYLL 239
++ I VS + + T+P V ++ E P E ++TAC+ FT+EYLL
Sbjct: 188 VTGFFIAVSVITNVVETVPCGTVPGSK----ELPCGERYSVAFFCLDTACVMIFTVEYLL 243
Query: 240 RLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAVQALRIMRIAR 299
RLF++P++ F S M+I+DV+AI+P+Y+ L +T+ +V A LR+ R+ R
Sbjct: 244 RLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNN-------EDVSGAFVTLRVFRVFR 296
Query: 300 IFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQ 359
IFK +RHS GL+ L Y LK ELG LL L + I +F+ + + E+ + F SIP
Sbjct: 297 IFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPA 356
Query: 360 SFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVR-YYNKQRV 418
SFW+ I+TMTT+GYGD+ PKT GK+ +I L GV+ IALP+ I++NF R Y+ QR
Sbjct: 357 SFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRA 416
Query: 419 LETAAKHELELMELNSSSGGEGKTGGSRSDLDNLPPEPAGKEAPSCSSRLKLSHSDTFIP 478
+ A+ + L + + KTG S + L + EA + + H
Sbjct: 417 DKRRAQKKARLARIRVA-----KTGSSNAYLHS-KRNGLLNEALELTGTPEEEHMGKTTS 470
Query: 479 LLTEEKHH 486
L+ + HH
Sbjct: 471 LIESQHHH 478
>gi|4826782 potassium voltage-gated channel, shaker-related
subfamily, member 2 [Homo sapiens]
Length = 499
Score = 230 bits (587), Expect = 2e-60
Identities = 142/434 (32%), Positives = 234/434 (53%), Gaps = 58/434 (13%)
Query: 25 IVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYDPGKREFYFDRDPD 84
+V+N+ G+R L+Q+PET L + + +DP + E++FDR+
Sbjct: 35 VVINISGLRFETQLKTLAQFPETLLGDPKKRMRY-----------FDPLRNEYFFDRNRP 83
Query: 85 AFKCVIEVYYFGEVHMKKGICPICFKNEMDFWKVDLKFLDDCCKSHLSEKREELEEIARR 144
+F ++ Y G + P+ D + +++F E EE E+ R
Sbjct: 84 SFDAILYYYQSGGRLRRPVNVPL------DIFSEEIRFY---------ELGEEAMEMFRE 128
Query: 145 VQLILDDLGVDAAEGRWRRCQKCVWKFLEKPESSCPARVVAVLSFLLILVSSVVMCMGTI 204
+ + + E + Q+ VW E PESS PAR++A++S ++IL+S V C+ T+
Sbjct: 129 DEGYIKEEERPLPENEF---QRQVWLLFEYPESSGPARIIAIVSVMVILISIVSFCLETL 185
Query: 205 PEL--QVLDAEGNRVEHPTLEN-----------------VETACIGWFTLEYLLRLFSSP 245
P + D G+ V T N VET CI WF+ E+L+R F+ P
Sbjct: 186 PIFRDENEDMHGSGVTFHTYSNSTIGYQQSTSFTDPFFIVETLCIIWFSFEFLVRFFACP 245
Query: 246 NKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMELTNVQQAV-----QALRIMRIARI 300
+K F + MNI+D++AI+P++++L T L + + QQA+ + +R++R+ RI
Sbjct: 246 SKAGFFTNIMNIIDIVAIIPYFITLG-TELAEKPEDAQQGQQAMSLAILRVIRLVRVFRI 304
Query: 301 FKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIFVFSALGYTMEQSHPETLFKSIPQS 360
FKL+RHS GLQ L LK S +ELGLL+ +L +G+ +FS+ Y E E+ F SIP +
Sbjct: 305 FKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDA 364
Query: 361 FWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVIAIALPIHPIINNFVRYYNKQRVLE 420
FWWA+++MTTVGYGD+ P T GK+ ++ + GV+ IALP+ I++NF +Y++ E
Sbjct: 365 FWWAVVSMTTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHR----E 420
Query: 421 TAAKHELELMELNS 434
T + + + +++ S
Sbjct: 421 TEGEEQAQYLQVTS 434
>gi|4504817 potassium voltage-gated channel, shaker-related
subfamily, member 4 [Homo sapiens]
Length = 653
Score = 228 bits (580), Expect = 1e-59
Identities = 151/440 (34%), Positives = 233/440 (52%), Gaps = 70/440 (15%)
Query: 13 GSQSSAASDDIE-IVVNVGGVRQVLYGDLLSQYPETRLAELINCLAGGYDTIFSLCDDYD 71
G S SD E +V+NV G+R L+Q+PET L + +D
Sbjct: 165 GYSSVRYSDCCERVVINVSGLRFETQMKTLAQFPETLLGDPEK-----------RTQYFD 213
Query: 72 PGKREFYFDRDPDAFKCVIEVYYFGEVHMKKGICPI-CFKNEMDFWKVD----LKFLDDC 126
P + E++FDR+ +F ++ Y G + P F E+ F+++ LKF +D
Sbjct: 214 PLRNEYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFRED- 272
Query: 127 CKSHLSEKREELEEIARRVQLILDDLGVDAAEGRWRRCQKCVWKFLEKPESSCPARVVAV 186
REE +D + E + K +W E PESS PAR +A+
Sbjct: 273 ----EGFVREE------------EDRALPENEFK-----KQIWLLFEYPESSSPARGIAI 311
Query: 187 LSFLLILVSSVVMCMGTIPELQ-------VLDAEG-----NRVEHPTLEN---------- 224
+S L+IL+S V+ C+ T+PE + L A G N P LEN
Sbjct: 312 VSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTSAPHLENSGHTIFNDPF 371
Query: 225 --VETACIGWFTLEYLLRLFSSPNKLHFALSFMNIVDVLAILPFYVSLTLTHLGARMMEL 282
VET CI WF+ E+++R F+ P++ F + MNI+D+++ILP++++L T L +
Sbjct: 372 FIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLG-TDLAQQQGGG 430
Query: 283 TNVQQAVQA------LRIMRIARIFKLARHSSGLQTLTYALKRSFKELGLLLMYLAVGIF 336
QQ + +R++R+ RIFKL+RHS GLQ L + L+ S +ELGLL+ +L +G+
Sbjct: 431 NGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVI 490
Query: 337 VFSALGYTMEQSHPETLFKSIPQSFWWAIITMTTVGYGDIYPKTTLGKLNAAISFLCGVI 396
+FS+ Y E P T F+SIP +FWWA++TMTTVGYGD+ P T GK+ ++ + GV+
Sbjct: 491 LFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVL 550
Query: 397 AIALPIHPIINNFVRYYNKQ 416
IALP+ I++NF +Y+++
Sbjct: 551 TIALPVPVIVSNFNYFYHRE 570
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,906,691
Number of Sequences: 37866
Number of extensions: 842793
Number of successful extensions: 3019
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 158
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 2511
Number of HSP's gapped (non-prelim): 327
length of query: 494
length of database: 18,247,518
effective HSP length: 106
effective length of query: 388
effective length of database: 14,233,722
effective search space: 5522684136
effective search space used: 5522684136
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.