Guide to the Human Genome
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Search of human proteins with 19924161

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19924161 RPB5-mediating protein isoform b [Homo sapiens]
         (495 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19924161 RPB5-mediating protein isoform b [Homo sapiens]           994   0.0  
gi|19924159 RPB5-mediating protein isoform a [Homo sapiens]           970   0.0  
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]      50   5e-06
gi|110347443 TATA element modulatory factor 1 [Homo sapiens]           49   1e-05
gi|51477718 TATA box binding protein-associated factor, RNA poly...    47   4e-05
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    46   9e-05
gi|4504487 histidine rich calcium binding protein precursor [Hom...    46   9e-05
gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens]                   45   2e-04
gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens]                   45   2e-04
gi|21735415 centromere protein B [Homo sapiens]                        44   3e-04
gi|93141003 testican 3 isoform 1 [Homo sapiens]                        44   3e-04
gi|93141001 testican 3 isoform 2 [Homo sapiens]                        44   3e-04
gi|55956788 nucleolin [Homo sapiens]                                   44   3e-04
gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]    44   3e-04
gi|210032580 SET domain containing 1B [Homo sapiens]                   44   3e-04
gi|54607116 leiomodin 3 (fetal) [Homo sapiens]                         44   3e-04
gi|40353734 nucleophosmin 1 isoform 2 [Homo sapiens]                   43   6e-04
gi|119395727 cardiac calsequestrin 2 precursor [Homo sapiens]          42   0.001
gi|41281831 neuronal PAS domain protein 3 isoform 2 [Homo sapiens]     42   0.001
gi|11545847 neuronal PAS domain protein 3 isoform 1 [Homo sapiens]     42   0.001
gi|11545835 TSPY-like 2 [Homo sapiens]                                 42   0.001
gi|115529449 upstream binding transcription factor, RNA polymera...    42   0.001
gi|115529451 upstream binding transcription factor, RNA polymera...    42   0.001
gi|7657671 upstream binding transcription factor, RNA polymerase...    42   0.001
gi|18093112 ABT1-associated protein [Homo sapiens]                     42   0.001
gi|42740903 MTERF domain containing 2 [Homo sapiens]                   42   0.002
gi|15559211 RE1-silencing transcription factor [Homo sapiens]          41   0.002
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu...    41   0.003
gi|217330641 IWS1 homolog [Homo sapiens]                               41   0.003
gi|16445033 ACRC protein [Homo sapiens]                                41   0.003

>gi|19924161 RPB5-mediating protein isoform b [Homo sapiens]
          Length = 495

 Score =  994 bits (2571), Expect = 0.0
 Identities = 495/495 (100%), Positives = 495/495 (100%)

Query: 1   MWRGCARSRKRKKVDNDYNALRERLSTLPDKLSYNIMVPFGPFAFMPGKLVHTNEVTVLL 60
           MWRGCARSRKRKKVDNDYNALRERLSTLPDKLSYNIMVPFGPFAFMPGKLVHTNEVTVLL
Sbjct: 1   MWRGCARSRKRKKVDNDYNALRERLSTLPDKLSYNIMVPFGPFAFMPGKLVHTNEVTVLL 60

Query: 61  GDNWFAKCSAKQAVGLVEHRKEHVRKTIDDLKKVMKNFESRVEFTEDLQKMSDAAGDIVD 120
           GDNWFAKCSAKQAVGLVEHRKEHVRKTIDDLKKVMKNFESRVEFTEDLQKMSDAAGDIVD
Sbjct: 61  GDNWFAKCSAKQAVGLVEHRKEHVRKTIDDLKKVMKNFESRVEFTEDLQKMSDAAGDIVD 120

Query: 121 IREEIKCDFEFKAKHRIAHKPHSKPKTSDIFEADIANDVKSKDLLADKELWARLEELERQ 180
           IREEIKCDFEFKAKHRIAHKPHSKPKTSDIFEADIANDVKSKDLLADKELWARLEELERQ
Sbjct: 121 IREEIKCDFEFKAKHRIAHKPHSKPKTSDIFEADIANDVKSKDLLADKELWARLEELERQ 180

Query: 181 EELLGELDSKPDTVIANGEDTTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSG 240
           EELLGELDSKPDTVIANGEDTTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSG
Sbjct: 181 EELLGELDSKPDTVIANGEDTTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSG 240

Query: 241 QVNSQLNCSVNGSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNSIPTIYFSHT 300
           QVNSQLNCSVNGSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNSIPTIYFSHT
Sbjct: 241 QVNSQLNCSVNGSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNSIPTIYFSHT 300

Query: 301 VEPKRVRINTGKNTTLKFSEKKEEAKRKRKNSTGSGHSAQELPTIRTPADIYRAFVDVVN 360
           VEPKRVRINTGKNTTLKFSEKKEEAKRKRKNSTGSGHSAQELPTIRTPADIYRAFVDVVN
Sbjct: 301 VEPKRVRINTGKNTTLKFSEKKEEAKRKRKNSTGSGHSAQELPTIRTPADIYRAFVDVVN 360

Query: 361 GEYVPRKSILKSRSRENSVCSDTSESSAAEFDDRRGVLRSISCEEATCSDTSESILEEEP 420
           GEYVPRKSILKSRSRENSVCSDTSESSAAEFDDRRGVLRSISCEEATCSDTSESILEEEP
Sbjct: 361 GEYVPRKSILKSRSRENSVCSDTSESSAAEFDDRRGVLRSISCEEATCSDTSESILEEEP 420

Query: 421 QENQKKLLPLSVTPEAFSGTVIEKEFVSPSLTPPPAIAHPALPTIPERKEVLLEASEETG 480
           QENQKKLLPLSVTPEAFSGTVIEKEFVSPSLTPPPAIAHPALPTIPERKEVLLEASEETG
Sbjct: 421 QENQKKLLPLSVTPEAFSGTVIEKEFVSPSLTPPPAIAHPALPTIPERKEVLLEASEETG 480

Query: 481 KRVSKFKAARLQQKD 495
           KRVSKFKAARLQQKD
Sbjct: 481 KRVSKFKAARLQQKD 495


>gi|19924159 RPB5-mediating protein isoform a [Homo sapiens]
          Length = 535

 Score =  970 bits (2507), Expect = 0.0
 Identities = 484/484 (100%), Positives = 484/484 (100%)

Query: 12  KKVDNDYNALRERLSTLPDKLSYNIMVPFGPFAFMPGKLVHTNEVTVLLGDNWFAKCSAK 71
           KKVDNDYNALRERLSTLPDKLSYNIMVPFGPFAFMPGKLVHTNEVTVLLGDNWFAKCSAK
Sbjct: 52  KKVDNDYNALRERLSTLPDKLSYNIMVPFGPFAFMPGKLVHTNEVTVLLGDNWFAKCSAK 111

Query: 72  QAVGLVEHRKEHVRKTIDDLKKVMKNFESRVEFTEDLQKMSDAAGDIVDIREEIKCDFEF 131
           QAVGLVEHRKEHVRKTIDDLKKVMKNFESRVEFTEDLQKMSDAAGDIVDIREEIKCDFEF
Sbjct: 112 QAVGLVEHRKEHVRKTIDDLKKVMKNFESRVEFTEDLQKMSDAAGDIVDIREEIKCDFEF 171

Query: 132 KAKHRIAHKPHSKPKTSDIFEADIANDVKSKDLLADKELWARLEELERQEELLGELDSKP 191
           KAKHRIAHKPHSKPKTSDIFEADIANDVKSKDLLADKELWARLEELERQEELLGELDSKP
Sbjct: 172 KAKHRIAHKPHSKPKTSDIFEADIANDVKSKDLLADKELWARLEELERQEELLGELDSKP 231

Query: 192 DTVIANGEDTTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVN 251
           DTVIANGEDTTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVN
Sbjct: 232 DTVIANGEDTTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVN 291

Query: 252 GSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNSIPTIYFSHTVEPKRVRINTG 311
           GSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNSIPTIYFSHTVEPKRVRINTG
Sbjct: 292 GSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNSIPTIYFSHTVEPKRVRINTG 351

Query: 312 KNTTLKFSEKKEEAKRKRKNSTGSGHSAQELPTIRTPADIYRAFVDVVNGEYVPRKSILK 371
           KNTTLKFSEKKEEAKRKRKNSTGSGHSAQELPTIRTPADIYRAFVDVVNGEYVPRKSILK
Sbjct: 352 KNTTLKFSEKKEEAKRKRKNSTGSGHSAQELPTIRTPADIYRAFVDVVNGEYVPRKSILK 411

Query: 372 SRSRENSVCSDTSESSAAEFDDRRGVLRSISCEEATCSDTSESILEEEPQENQKKLLPLS 431
           SRSRENSVCSDTSESSAAEFDDRRGVLRSISCEEATCSDTSESILEEEPQENQKKLLPLS
Sbjct: 412 SRSRENSVCSDTSESSAAEFDDRRGVLRSISCEEATCSDTSESILEEEPQENQKKLLPLS 471

Query: 432 VTPEAFSGTVIEKEFVSPSLTPPPAIAHPALPTIPERKEVLLEASEETGKRVSKFKAARL 491
           VTPEAFSGTVIEKEFVSPSLTPPPAIAHPALPTIPERKEVLLEASEETGKRVSKFKAARL
Sbjct: 472 VTPEAFSGTVIEKEFVSPSLTPPPAIAHPALPTIPERKEVLLEASEETGKRVSKFKAARL 531

Query: 492 QQKD 495
           QQKD
Sbjct: 532 QQKD 535


>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
          Length = 1390

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 49/193 (25%), Positives = 74/193 (38%), Gaps = 30/193 (15%)

Query: 207 EKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDD----DD 262
           E E+ N N+    +  D       D  +++   G V S    S  G    H DD    DD
Sbjct: 210 ETEESNLNMYTRGKQKDIQ---RTDEETTDNQEGSVES----SEEGEDQEHEDDGEDEDD 262

Query: 263 DDDDDDDDDNIDDDDGDNDHEALGVGDNSIPTIYFSHTVEPKRVRINTGKNTTLKFSEKK 322
           +DDDDDDDD+ DDDD D++ E  G  +N             KR  +   K T    +  +
Sbjct: 263 EDDDDDDDDDDDDDDEDDEDEEDGEEENQ------------KRYYLRQRKATVYYQAPLE 310

Query: 323 EEAKRKRKNSTGSGHSAQELPTIRTPADIYRAFVDVVNGEYVPRKSILKSRSRENSVCSD 382
           +   +++ N   SG ++   P        YR         Y  R +  +     +   S 
Sbjct: 311 KPRHQRKPNIFYSGPASPARPR-------YRLSSAGPRSPYCKRMNRRRHAIHSSDSTSS 363

Query: 383 TSESSAAEFDDRR 395
           +S      F+ RR
Sbjct: 364 SSSEDEQHFERRR 376


>gi|110347443 TATA element modulatory factor 1 [Homo sapiens]
          Length = 1093

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 63/303 (20%), Positives = 124/303 (40%), Gaps = 16/303 (5%)

Query: 157 NDVKSKDLLADKELWARLEELERQEELLGELDSKPDTVIANGEDTTSSEE----EKEDRN 212
           ++  ++ L A+ +  A   + ++ E+      S P +  ++G  TTS  E    E     
Sbjct: 211 SNTSTQSLTAETKDIALEPKEQKHEDRQSNTPSPPVSTFSSGTSTTSDIEVLDHESVISE 270

Query: 213 TNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDDDDN 272
           ++ ++  + TDS +  H    S +  S     + N   +      S    D  +  D  +
Sbjct: 271 SSASSRQETTDSKSSLHLMQTSFQLLSASACPEYNRLDDFQKLTESCCSSDAFERIDSFS 330

Query: 273 IDDDDG------DNDHEALGVGDNSIPTIYFSHTVEPKRVRINTGK----NTTLKFSEKK 322
           +   D       ++D E  G G   +P I  S T + K V    GK    N TL    ++
Sbjct: 331 VQSLDSRSVSEINSDDELSGKGYALVPIIVNSSTPKSKTVESAEGKSEEVNETLVIPTEE 390

Query: 323 EEAKRKRKNSTGSGHSAQELPTIRTPADIYRAFVDVVNGEYVPRKSILKSRSRENSVCSD 382
            E +   +++T       ++    TP +  +  +D V  +  P +S  ++ S +  VC  
Sbjct: 391 AEMEESGRSATPVNCEQPDILVSSTPINEGQTVLDKVAEQCEPAESQPEALSEKEDVCK- 449

Query: 383 TSESSAAEFDDRRGVLRSISCEEATCSDTSESILEEEPQENQKKLLPLSVTPEAFSGTVI 442
           T E    + + R   L S+S E+A   +  ++ L++E    +++   +S   + F+  + 
Sbjct: 450 TVEFLNEKLEKREAQLLSLSKEKALLEEAFDN-LKDEMFRVKEESSSISSLKDEFTQRIA 508

Query: 443 EKE 445
           E E
Sbjct: 509 EAE 511



 Score = 30.0 bits (66), Expect = 5.0
 Identities = 44/205 (21%), Positives = 88/205 (42%), Gaps = 26/205 (12%)

Query: 62  DNWFAKCSAKQAVGLVEHRKEHVRKTIDDLKKV-------MKNFESRVEFTE-DLQKMSD 113
           +N  AK + K  V  +E   +H+++ +D  ++V       +K   S VE  E DL ++  
Sbjct: 587 ENMVAKLNKK--VKELEEELQHLKQVLDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQV 644

Query: 114 AAGDIVDIREEIKCDFEFKAKHRIAHKPHSKPKTSDIFEADIANDVKSKDLLADKELWAR 173
              ++ +    I+   +   K        +  K S+  EA ++ ++K+K+ L+     A+
Sbjct: 645 DMDELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEAALSREMKAKEELSAALEKAQ 704

Query: 174 LEELERQEEL---LGELD---SKPDTVIANGEDTTSSE--------EEKEDRNTNVNAMH 219
            E  ++QE L   +G+L     + +   A  ED    E        +E E+RN  ++   
Sbjct: 705 EEARQQQETLAIQVGDLRLALQRTEQAAARKEDYLRHEIGELQQRLQEAENRNQELS--Q 762

Query: 220 QVTDSHTPCHKDVASSEPFSGQVNS 244
            V+ +  P  + + + +   G   S
Sbjct: 763 SVSSTTRPLLRQIENLQATLGSQTS 787


>gi|51477718 TATA box binding protein-associated factor, RNA
           polymerase II, Q [Homo sapiens]
          Length = 462

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 22/77 (28%), Positives = 42/77 (54%)

Query: 253 SSSYHSDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNSIPTIYFSHTVEPKRVRINTGK 312
           S S + DD+D+DD+D+D+D  +D+D D + E     +  +     +  +E  + R N G 
Sbjct: 328 SRSNNDDDEDEDDEDEDEDEDEDEDEDKEEEEEDCSEEYLERQLQAEFIESGQYRANEGT 387

Query: 313 NTTLKFSEKKEEAKRKR 329
           ++ +   +K+ E K K+
Sbjct: 388 SSIVMEIQKQIEKKEKK 404


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 48/246 (19%), Positives = 94/246 (38%), Gaps = 10/246 (4%)

Query: 179 RQEELLGELDSKPDTVIANGEDTTSSEEEKEDRNT-NVNAMHQVTDSHTPCHKDVASSEP 237
           + E    + DSK D+  +N  D++ + +  +  N+ N +     +DS        +S+  
Sbjct: 628 KSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSS 687

Query: 238 FSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDDDDNIDDDDGDN--DHEALGVGDNSIPTI 295
            S   +   N S +  SS  SD D  D  D  + N  D D  N  D        +S  + 
Sbjct: 688 DSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSS 747

Query: 296 YFSHTVEPKRVRINTGKNTTLKFSEKKEEAKRKRKNSTGSGHSAQELPTIRTPADIYRAF 355
             S++ +      ++  + +   S+  + +     + +    ++ +       +D   + 
Sbjct: 748 DSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSS 807

Query: 356 VDVVNGEYVPRKSILKSRSRENSVCSDTSESS-------AAEFDDRRGVLRSISCEEATC 408
               + +     S   S S  +S  SD+S SS       +++  D     RS S   +  
Sbjct: 808 DSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDS 867

Query: 409 SDTSES 414
           SD+S+S
Sbjct: 868 SDSSDS 873



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 42/236 (17%), Positives = 84/236 (35%), Gaps = 7/236 (2%)

Query: 186 ELDSKPDTVIANGEDTTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQ 245
           E D    T   N  D+  +     D N   ++    +DS      D ++S   S   +S 
Sbjct: 511 EDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSD 570

Query: 246 LNCSVNGSSSYHSDDDDDDDDDDD-------DDNIDDDDGDNDHEALGVGDNSIPTIYFS 298
            + S + S S  SD D  D  D D        D+ D  D  +  ++    D+   +    
Sbjct: 571 SSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSE 630

Query: 299 HTVEPKRVRINTGKNTTLKFSEKKEEAKRKRKNSTGSGHSAQELPTIRTPADIYRAFVDV 358
                   + ++  + +   S+  + +     +++     + +     + +D   +    
Sbjct: 631 SDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSS 690

Query: 359 VNGEYVPRKSILKSRSRENSVCSDTSESSAAEFDDRRGVLRSISCEEATCSDTSES 414
            + +         S    +S  SD+S+SS +   D      S S + +  SD+S+S
Sbjct: 691 DSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDS 746



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 53/245 (21%), Positives = 96/245 (39%), Gaps = 26/245 (10%)

Query: 185 GELDSKPDTVIANGEDTTSSEEEKEDR-NTNVNAMHQVTDSHTPCHKDVASSEPFSGQVN 243
           G + ++ + V   G    S    K    NT  ++     DS+    K +   +P S   +
Sbjct: 412 GNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDES 471

Query: 244 ---------SQLNCSVNGSSSYHSDDDDDDDDDDDDDNIDDDDGD-----NDHEALGVGD 289
                    S  N S  G +SY+SD+  D+ +  D    +DDD D     N+ ++ G G+
Sbjct: 472 NGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGN 531

Query: 290 NSIPTIYFSHTVEPKRVRINTGKNTTLKFSEKKEEAKRKRKNSTGSGHSAQELPTIRTPA 349
           N       S + + K    ++  + +   S+  + +     +S  S  S          +
Sbjct: 532 NGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSS 591

Query: 350 DIYRAFVDVVNGEYVPRKSILKSRSRENSVCSDTSESSAAEFDDRRGVLRSISCEEATCS 409
           D         +       S   S S ++S  SD+S+SS ++ D  +    S S +  + S
Sbjct: 592 D---------SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKS--ESDSSDSDSKS 640

Query: 410 DTSES 414
           D+S+S
Sbjct: 641 DSSDS 645



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 44/228 (19%), Positives = 88/228 (38%), Gaps = 12/228 (5%)

Query: 188 DSKPDTVIANGEDTTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLN 247
           DS   +  +N  D+  S    +  +++ N+      S +    D + S+  +   +S  +
Sbjct: 772 DSSDSSDSSNSSDSNDSSNSSDSSDSS-NSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSS 830

Query: 248 CSVNGSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNSIPTIYFSHTVEPKRVR 307
            S + S+S  S D  D  D  D D+ +  D  N  ++    D+S                
Sbjct: 831 DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSS----------NSSDSS 880

Query: 308 INTGKNTTLKFSEKKEEAKRKRKNSTGSGHSAQELPTIRTPADIYRAFVDVVNGEYVPRK 367
            ++  N +   S+  + +     +S+ S +S+    +  +      +     +       
Sbjct: 881 DSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSN 940

Query: 368 SILKSRSRENSVCSDTSESS-AAEFDDRRGVLRSISCEEATCSDTSES 414
           S   S S ++S  SD+S SS ++   D      S S + +  SD+S+S
Sbjct: 941 SSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDS 988



 Score = 37.4 bits (85), Expect = 0.032
 Identities = 44/229 (19%), Positives = 89/229 (38%), Gaps = 8/229 (3%)

Query: 190 KPDTVIANGEDTTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCS 249
           K D+  ++  D+++S +  +  +++ +  +  +DS +       SS+  S   ++  + S
Sbjct: 546 KSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSS 605

Query: 250 VNGSSSYHSDDDDDDDDDDD----DDNIDDDDGDNDHEALGVGDNSIPTIYFSHTVEPKR 305
            +  SS  SD  D  D   D    + +  D D  +D       D+S  +     +     
Sbjct: 606 DSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNS 665

Query: 306 VRINTGKNTTLKFSEKKEEAKRKRKNSTGSGHSAQELPTIRTPADIYRAFVDVVNGEYVP 365
              +   +++   S           +S+ S +S++   +  +         D  N     
Sbjct: 666 SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSD 725

Query: 366 RKSILKSRSRENSVCSDTSESSAAEFDDRRGVLRSISCEEATCSDTSES 414
             S   S S ++S  SD+S+SS    D       S S + +  SD+S+S
Sbjct: 726 SDSSNSSDSSDSSNSSDSSDSS----DSSNSSDSSDSSDSSNSSDSSDS 770



 Score = 35.8 bits (81), Expect = 0.092
 Identities = 26/153 (16%), Positives = 62/153 (40%), Gaps = 1/153 (0%)

Query: 188  DSKPDTVIANGEDTTSSEEEKEDRNTNVNA-MHQVTDSHTPCHKDVASSEPFSGQVNSQL 246
            DS   +  +N  D++ S E  +  +++ ++     +DS        +S+   S   +   
Sbjct: 1131 DSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1190

Query: 247  NCSVNGSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNSIPTIYFSHTVEPKRV 306
            + S +  SS  SD  D  D  D  D+ D  D  +  ++    ++S  +     +      
Sbjct: 1191 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSS 1250

Query: 307  RINTGKNTTLKFSEKKEEAKRKRKNSTGSGHSA 339
              +   +++   S+  +E+  + K+  G+ + +
Sbjct: 1251 DSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGS 1283



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 42/220 (19%), Positives = 81/220 (36%), Gaps = 27/220 (12%)

Query: 197  NGEDTTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGS--S 254
            +   + SSE      N+N +     +DS        +S    S   ++  + S + S  S
Sbjct: 917  SSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDS 976

Query: 255  SYHSDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNSIPTIYFSHTVEPKRVRINTGKNT 314
            S  S+  D  D  D  D+ D  D  N  ++    D+S      S++ +      ++  + 
Sbjct: 977  SDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS----SNSSDSSNSSDSSNSSD 1032

Query: 315  TLKFSEKKEEAKRKRKNSTGSGHSAQELPTIRTPADIYRAFVDVVNGEYVPRKSILKSRS 374
            +   S+  + +     + +    ++ +       +D                     S S
Sbjct: 1033 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD--------------------SSDS 1072

Query: 375  RENSVCSDTSESSAAEFDDRRGVLRSISCEEATCSDTSES 414
             ++S  SD+SESS +  D       S S + +  SD+S+S
Sbjct: 1073 SDSSDSSDSSESSDSS-DSSNSSDSSDSSDSSDSSDSSDS 1111



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 19/95 (20%), Positives = 38/95 (40%)

Query: 197  NGEDTTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSY 256
            + + + SSE      ++N +     +DS        +S    S   ++  + S +  SS 
Sbjct: 1075 SSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1134

Query: 257  HSDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNS 291
             SD  +  D  D  ++ D  D  +  ++    D+S
Sbjct: 1135 SSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS 1169


>gi|4504487 histidine rich calcium binding protein precursor [Homo
           sapiens]
          Length = 699

 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 10/88 (11%)

Query: 198 GEDTTSSEEEKEDRNTNV-NAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSY 256
           GE+    EEE+E+ +T   +  H+     +   +DV+      G  +             
Sbjct: 192 GEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHHHGPSHRHQG--------- 242

Query: 257 HSDDDDDDDDDDDDDNIDDDDGDNDHEA 284
           H +DDDDDDDDDDDD+ DD   +  H+A
Sbjct: 243 HEEDDDDDDDDDDDDDDDDVSIEYRHQA 270


>gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens]
          Length = 259

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 12/91 (13%)

Query: 258 SDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNSIPTIYFSHTVEPKRVRINTGKNTTLK 317
           +D+DDDDDD++DDD  DDDD  +D EA    +   P          K +R    KN    
Sbjct: 160 ADEDDDDDDEEDDDEDDDDDDFDDEEA----EEKAPV--------KKSIRDTPAKNAQKS 207

Query: 318 FSEKKEEAKRKRKNSTGSGHSAQELPTIRTP 348
               K+        S G     ++  T +TP
Sbjct: 208 NQNGKDSKPSSTPRSKGQESFKKQEKTPKTP 238



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 24/87 (27%), Positives = 40/87 (45%), Gaps = 16/87 (18%)

Query: 194 VIANGEDTTSSEEEKED-RNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNG 252
           ++A  ED  S +EE+ED +  +++                  S P  G    Q    +  
Sbjct: 116 LVAVEEDAESEDEEEEDVKLLSISGKR---------------SAPGGGSKVPQKKVKLAA 160

Query: 253 SSSYHSDDDDDDDDDDDDDNIDDDDGD 279
                 DD++DDD+DDDDD+ DD++ +
Sbjct: 161 DEDDDDDDEEDDDEDDDDDDFDDEEAE 187


>gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens]
          Length = 294

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 12/91 (13%)

Query: 258 SDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNSIPTIYFSHTVEPKRVRINTGKNTTLK 317
           +D+DDDDDD++DDD  DDDD  +D EA    +   P          K +R    KN    
Sbjct: 160 ADEDDDDDDEEDDDEDDDDDDFDDEEA----EEKAPV--------KKSIRDTPAKNAQKS 207

Query: 318 FSEKKEEAKRKRKNSTGSGHSAQELPTIRTP 348
               K+        S G     ++  T +TP
Sbjct: 208 NQNGKDSKPSSTPRSKGQESFKKQEKTPKTP 238



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 24/87 (27%), Positives = 40/87 (45%), Gaps = 16/87 (18%)

Query: 194 VIANGEDTTSSEEEKED-RNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNG 252
           ++A  ED  S +EE+ED +  +++                  S P  G    Q    +  
Sbjct: 116 LVAVEEDAESEDEEEEDVKLLSISGKR---------------SAPGGGSKVPQKKVKLAA 160

Query: 253 SSSYHSDDDDDDDDDDDDDNIDDDDGD 279
                 DD++DDD+DDDDD+ DD++ +
Sbjct: 161 DEDDDDDDEEDDDEDDDDDDFDDEEAE 187


>gi|21735415 centromere protein B [Homo sapiens]
          Length = 599

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 34/127 (26%), Positives = 58/127 (45%), Gaps = 4/127 (3%)

Query: 175 EELERQEELLGELDSKPDTVIANGE-DTTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVA 233
           EE E +EE  GE +   +      E D  S EEE+ED  ++   + +  D      +   
Sbjct: 427 EEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGL-EAEDWAQGVVEAGG 485

Query: 234 SSEPFSGQVNSQLNCS--VNGSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNS 291
           S   +  Q  +Q      + G     SD +++DD+++DD++ DDDD + D + + V    
Sbjct: 486 SFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFG 545

Query: 292 IPTIYFS 298
               YF+
Sbjct: 546 EAMAYFA 552



 Score = 32.7 bits (73), Expect = 0.78
 Identities = 31/159 (19%), Positives = 65/159 (40%), Gaps = 15/159 (9%)

Query: 153 ADIANDVKSKDLLADKELWARLEELERQEELLGELDSKP--DTVIANGEDTTSSEEEKED 210
           A I   +KS+    ++E     EE E +EE  GE + +   +     GE     EEE+ +
Sbjct: 395 ATITTSLKSEGEEEEEE-----EEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVE 449

Query: 211 RNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSS--------YHSDDDD 262
              +V++  +  +      + + + +   G V +  +    G+          +    +D
Sbjct: 450 EEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGED 509

Query: 263 DDDDDDDDDNIDDDDGDNDHEALGVGDNSIPTIYFSHTV 301
            D D +++D+ ++DD D D +      + +P   F   +
Sbjct: 510 SDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGEAM 548


>gi|93141003 testican 3 isoform 1 [Homo sapiens]
          Length = 433

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 26/84 (30%)

Query: 226 TPCHKDVAS--------SEPFSGQVNSQLNCSVN-------GSSSYH--SDDDDDDDD-- 266
           T CH  V          +E    ++N   +C+++        S  +H  +DD+DD+DD  
Sbjct: 347 TQCHGSVGQCWCVDRYGNEVMGSRINGVADCAIDFEISGDFASGDFHEWTDDEDDEDDIM 406

Query: 267 -------DDDDDNIDDDDGDNDHE 283
                  DDD+D  DDDDG +DH+
Sbjct: 407 NDEDEIEDDDEDEGDDDDGGDDHD 430


>gi|93141001 testican 3 isoform 2 [Homo sapiens]
          Length = 436

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 26/84 (30%), Positives = 40/84 (47%), Gaps = 26/84 (30%)

Query: 226 TPCHKDVAS--------SEPFSGQVNSQLNCSVN-------GSSSYH--SDDDDDDDD-- 266
           T CH  V          +E    ++N   +C+++        S  +H  +DD+DD+DD  
Sbjct: 350 TQCHGSVGQCWCVDRYGNEVMGSRINGVADCAIDFEISGDFASGDFHEWTDDEDDEDDIM 409

Query: 267 -------DDDDDNIDDDDGDNDHE 283
                  DDD+D  DDDDG +DH+
Sbjct: 410 NDEDEIEDDDEDEGDDDDGGDDHD 433


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 8/86 (9%)

Query: 199 EDTTSSEEEKEDRNTNVNAMHQVTDSHTPCH-KDVASSEPFSGQVNSQLNCSVNGSSSYH 257
           ED    E++++D +   +   +     TP   K  A   P   +       +V       
Sbjct: 187 EDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAK-------NVAEDEDEE 239

Query: 258 SDDDDDDDDDDDDDNIDDDDGDNDHE 283
            DD+D+DDDDD+DD  DDD+ D + E
Sbjct: 240 EDDEDEDDDDDEDDEDDDDEDDEEEE 265



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 29/129 (22%), Positives = 60/129 (46%), Gaps = 6/129 (4%)

Query: 158 DVKSKDLLADKELWARLEELERQEELLGELDSKPDTVIANGEDTTSSEEEKEDRNTNVNA 217
           + K +D   +++  +  +E + ++E   E + +P  + A      S +E+ ED   + + 
Sbjct: 139 NAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDED- 197

Query: 218 MHQVTDSHTPCHKDVASSEPFSGQVNSQL---NCSVNGSSSYHSDDDDDDDDDDDDDNID 274
                D      ++   + P  G+  +++               +DD+D+DDDDD+D+ D
Sbjct: 198 --DDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDED 255

Query: 275 DDDGDNDHE 283
           DDD D++ E
Sbjct: 256 DDDEDDEEE 264



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 24/87 (27%), Positives = 43/87 (49%), Gaps = 24/87 (27%)

Query: 199 EDTTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHS 258
           ED  S E+E++D + + +      D   P     A++ P S                   
Sbjct: 149 EDDDSEEDEEDDEDEDEDE-----DEIEPAAMKAAAAAPAS------------------- 184

Query: 259 DDDDDDDDDDDDDNIDDDDGDNDHEAL 285
           +D+DD+DD+DD+D+ DD++ D++ EA+
Sbjct: 185 EDEDDEDDEDDEDDDDDEEDDSEEEAM 211



 Score = 38.1 bits (87), Expect = 0.019
 Identities = 13/35 (37%), Positives = 23/35 (65%)

Query: 251 NGSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHEAL 285
           NG ++   D D+++DDD ++D  DD+D D D + +
Sbjct: 136 NGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEI 170



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 11/28 (39%), Positives = 21/28 (75%)

Query: 259 DDDDDDDDDDDDDNIDDDDGDNDHEALG 286
           +DD+DDDD+DD++  ++++ +   EA G
Sbjct: 251 EDDEDDDDEDDEEEEEEEEEEPVKEAPG 278



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 17/60 (28%), Positives = 31/60 (51%), Gaps = 5/60 (8%)

Query: 226 TPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHEAL 285
           TP  K  A   P  G  N +   +     S   +DDD ++D++DD++ D+D+ + +  A+
Sbjct: 121 TPGKKGAAI--PAKGAKNGK---NAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAM 175


>gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]
          Length = 1759

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 16/36 (44%), Positives = 27/36 (75%)

Query: 258  SDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNSIP 293
            ++DD+D+DDD+DDD+ DDD+ D+D +     + S+P
Sbjct: 1689 AEDDEDEDDDEDDDDEDDDEDDDDEDLRTDSEESLP 1724



 Score = 37.0 bits (84), Expect = 0.041
 Identities = 16/45 (35%), Positives = 23/45 (51%)

Query: 233  ASSEPFSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDDDDNIDDDD 277
            A+ E        +L      +     +DDD+DDDD+DDD  DDD+
Sbjct: 1669 AAGESSQEDEEEELELPEEEAEDDEDEDDDEDDDDEDDDEDDDDE 1713



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 13/26 (50%), Positives = 20/26 (76%)

Query: 259  DDDDDDDDDDDDDNIDDDDGDNDHEA 284
            DDD+DDD+DDDD+++  D  ++  EA
Sbjct: 1701 DDDEDDDEDDDDEDLRTDSEESLPEA 1726



 Score = 29.6 bits (65), Expect = 6.6
 Identities = 18/76 (23%), Positives = 36/76 (47%), Gaps = 7/76 (9%)

Query: 223  DSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDDDD----DDDDDDDDDNIDDDDG 278
            D+  P   D A+  P  G   +    +  G SS   ++++    +++ +DD+D  DD+D 
Sbjct: 1645 DAGDPGPPDAAAPGPREGAAAA---AAAAGESSQEDEEEELELPEEEAEDDEDEDDDEDD 1701

Query: 279  DNDHEALGVGDNSIPT 294
            D++ +     D  + T
Sbjct: 1702 DDEDDDEDDDDEDLRT 1717


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 70/312 (22%), Positives = 123/312 (39%), Gaps = 67/312 (21%)

Query: 200  DTTSSEEEKEDR-NTNVNAMHQVTD-------SHTPCHKDVASSEP-------------- 237
            DTTSS ++K  R +T+V+   + ++       + TPC  ++A  +P              
Sbjct: 971  DTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPC--ELAKRDPKGVGVRRRPARPLE 1028

Query: 238  --FSGQVNSQLNCSVNGSSSYH---SDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNSI 292
                G+ + + + S    S+     ++++++++DDDDDD+ D D+ +ND E   + + S 
Sbjct: 1029 LDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASE 1088

Query: 293  PTIYFSHTVEPKRVRINTGKNTTLKFSEKKEEAKRKRKNSTGSGHSAQELPTIRTPADIY 352
                   + E + V I T K      SE  E ++ +  + +    S  E           
Sbjct: 1089 KD--EGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDE----------- 1135

Query: 353  RAFVDVVNGEYVPRKSILKSRSRENSVCSDTSESSAAEFDDRRG----------VLRSIS 402
                     E V  +   +    E  V  ++  S+  E  ++ G           + S+ 
Sbjct: 1136 ---------EEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLG 1186

Query: 403  CEEATCSDTSESILEEEPQENQKKLLPLSVTPEAFSGTVIEKEFVSPS----LTP-PPAI 457
             EE    +T     EE P    +  LP+ V   A S    E+  +S      L+P PPA 
Sbjct: 1187 MEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAK 1246

Query: 458  AHPALPTI-PER 468
               A P + PER
Sbjct: 1247 EVEARPPLSPER 1258


>gi|54607116 leiomodin 3 (fetal) [Homo sapiens]
          Length = 560

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 29/119 (24%), Positives = 51/119 (42%), Gaps = 21/119 (17%)

Query: 165 LADKELWARLEELERQEELLGELDSKPDTVIANGEDTTSSEEEKEDRNTNVNAMHQVTDS 224
           L D   W +      +EE +      P T + + E T    EE E RN N+    +    
Sbjct: 71  LVDYMYWEKASRRMLEEERV------PVTFVKSEEKTQEEHEEIEKRNKNMAQYLK---- 120

Query: 225 HTPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHE 283
                      E  + ++ +    S   S+   +D++D++++DDDDD+  +DDG+   E
Sbjct: 121 -----------EKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEE 168


>gi|40353734 nucleophosmin 1 isoform 2 [Homo sapiens]
          Length = 265

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 17/27 (62%), Positives = 22/27 (81%)

Query: 258 SDDDDDDDDDDDDDNIDDDDGDNDHEA 284
           +D+DDDDDD++DDD  DDDD  +D EA
Sbjct: 160 ADEDDDDDDEEDDDEDDDDDDFDDEEA 186



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 24/87 (27%), Positives = 40/87 (45%), Gaps = 16/87 (18%)

Query: 194 VIANGEDTTSSEEEKED-RNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNG 252
           ++A  ED  S +EE+ED +  +++                  S P  G    Q    +  
Sbjct: 116 LVAVEEDAESEDEEEEDVKLLSISGKR---------------SAPGGGSKVPQKKVKLAA 160

Query: 253 SSSYHSDDDDDDDDDDDDDNIDDDDGD 279
                 DD++DDD+DDDDD+ DD++ +
Sbjct: 161 DEDDDDDDEEDDDEDDDDDDFDDEEAE 187



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 15/25 (60%), Positives = 20/25 (80%)

Query: 259 DDDDDDDDDDDDDNIDDDDGDNDHE 283
           DDDDDD++DDD+D+ DDD  D + E
Sbjct: 163 DDDDDDEEDDDEDDDDDDFDDEEAE 187


>gi|119395727 cardiac calsequestrin 2 precursor [Homo sapiens]
          Length = 399

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 20/57 (35%), Positives = 31/57 (54%), Gaps = 5/57 (8%)

Query: 227 PCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHE 283
           P   D+ ++E     +   L+  +N       DDD+DDDDDD+ D  D+DD D+D +
Sbjct: 347 PDDDDLPTAEELEDWIEDVLSGKINTE-----DDDEDDDDDDNSDEEDNDDSDDDDD 398



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 16/47 (34%), Positives = 28/47 (59%)

Query: 237 PFSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHE 283
           P + ++   +   ++G  +   DD+DDDDDD+ D+  +DD  D+D E
Sbjct: 353 PTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE 399


>gi|41281831 neuronal PAS domain protein 3 isoform 2 [Homo sapiens]
          Length = 920

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 46/234 (19%), Positives = 91/234 (38%), Gaps = 16/234 (6%)

Query: 196 ANGEDTTSSEEEKEDRN----TNVNAMHQVTDSHTPCHKDVASSEPFSGQV-NSQLNCSV 250
           +   +T+ SE + +D +     N N+      + +   +D       SG   ++ +NC+ 
Sbjct: 443 SESSETSDSESDSKDTSGITEDNENSKSDEKGNQSENSEDPEPDRKKSGNACDNDMNCND 502

Query: 251 NGSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNSIPTIYFSHT---------- 300
           +G SS + D  D DD  +  D  +   G++   ALG     +     S +          
Sbjct: 503 DGHSSSNPDSRDSDDSFEHSDFENPKAGEDGFGALGAMQIKVERYVESESDLRLQNCESL 562

Query: 301 VEPKRVRINTGKNTTLKFSEKKEEAKRKRKNSTGSGHSAQELPTIRTPADIYRAFVDVVN 360
                   ++      + S K ++ K++RK   G   S + L +  +P  +    V+   
Sbjct: 563 TSDSAKDSDSAGEAGAQASSKHQKRKKRRKRQKGGSASRRRLSSASSPGGLDAGLVEPPR 622

Query: 361 GEYVPRK-SILKSRSRENSVCSDTSESSAAEFDDRRGVLRSISCEEATCSDTSE 413
               P   S+LK ++  +   +  ++SS   +   R + R+ S    T   +SE
Sbjct: 623 LLSSPNSASVLKIKTEISEPINFDNDSSIWNYPPNREISRNESPYSMTKPPSSE 676


>gi|11545847 neuronal PAS domain protein 3 isoform 1 [Homo sapiens]
          Length = 901

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 46/234 (19%), Positives = 91/234 (38%), Gaps = 16/234 (6%)

Query: 196 ANGEDTTSSEEEKEDRN----TNVNAMHQVTDSHTPCHKDVASSEPFSGQV-NSQLNCSV 250
           +   +T+ SE + +D +     N N+      + +   +D       SG   ++ +NC+ 
Sbjct: 424 SESSETSDSESDSKDTSGITEDNENSKSDEKGNQSENSEDPEPDRKKSGNACDNDMNCND 483

Query: 251 NGSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNSIPTIYFSHT---------- 300
           +G SS + D  D DD  +  D  +   G++   ALG     +     S +          
Sbjct: 484 DGHSSSNPDSRDSDDSFEHSDFENPKAGEDGFGALGAMQIKVERYVESESDLRLQNCESL 543

Query: 301 VEPKRVRINTGKNTTLKFSEKKEEAKRKRKNSTGSGHSAQELPTIRTPADIYRAFVDVVN 360
                   ++      + S K ++ K++RK   G   S + L +  +P  +    V+   
Sbjct: 544 TSDSAKDSDSAGEAGAQASSKHQKRKKRRKRQKGGSASRRRLSSASSPGGLDAGLVEPPR 603

Query: 361 GEYVPRK-SILKSRSRENSVCSDTSESSAAEFDDRRGVLRSISCEEATCSDTSE 413
               P   S+LK ++  +   +  ++SS   +   R + R+ S    T   +SE
Sbjct: 604 LLSSPNSASVLKIKTEISEPINFDNDSSIWNYPPNREISRNESPYSMTKPPSSE 657


>gi|11545835 TSPY-like 2 [Homo sapiens]
          Length = 693

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 28/115 (24%), Positives = 52/115 (45%), Gaps = 10/115 (8%)

Query: 196 ANGEDTTSSEEEKEDRNTNVNAMHQVTDSH--TPCHKDVASSEPF------SGQVNSQLN 247
           A+  +TT + E  +D N N    ++ TD +   P + +      F          N+Q +
Sbjct: 499 ADDHETTDNNESADDNNENPEDNNKNTDDNEENPNNNENTYGNNFFKGGFWGSHGNNQDS 558

Query: 248 CSVNGSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNSIPTIYFSHTVE 302
              +  +   SDD+D+D ++ D++  DDD  + D+E  G  D+     Y+   +E
Sbjct: 559 SDSDNEADEASDDEDNDGNEGDNEGSDDDGNEGDNE--GSDDDDRDIEYYEKVIE 611



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 21/107 (19%), Positives = 51/107 (47%), Gaps = 15/107 (14%)

Query: 181 EELLGELDSKPDTV----IANGEDTTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSE 236
           E++  E+    +T+    I++  +TT   E  ++  T++N    + DS  P H +V ++E
Sbjct: 434 EDIFSEISDIDETIHDIKISDFMETTDYFETTDNEITDIN--ENICDSENPDHNEVPNNE 491

Query: 237 PFSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHE 283
                           +  + + D+++  DD++++  D++   +D+E
Sbjct: 492 TTDNN---------ESADDHETTDNNESADDNNENPEDNNKNTDDNE 529


>gi|115529449 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 11/89 (12%)

Query: 203 SSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDDDD 262
           S E+++ED +       +  D +    +D   S   S +  S+             D+++
Sbjct: 640 SEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESE-----------DGDENE 688

Query: 263 DDDDDDDDDNIDDDDGDNDHEALGVGDNS 291
           +DD+D+DDD  DD+D DN+ E      +S
Sbjct: 689 EDDEDEDDDEDDDEDEDNESEGSSSSSSS 717



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 15/39 (38%), Positives = 27/39 (69%), Gaps = 3/39 (7%)

Query: 253 SSSYHSDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNS 291
           S S   D++D+DD+D+D++  DD++GD+  +    GD+S
Sbjct: 638 SESEEDDEEDEDDEDEDEEEEDDENGDSSEDG---GDSS 673



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 14/50 (28%), Positives = 25/50 (50%), Gaps = 2/50 (4%)

Query: 237 PFSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDDDDNID--DDDGDNDHEA 284
           P S +   Q             DD+D+D++++DD+N D  +D GD+   +
Sbjct: 627 PKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESS 676


>gi|115529451 upstream binding transcription factor, RNA polymerase
           I isoform b [Homo sapiens]
          Length = 727

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 11/89 (12%)

Query: 203 SSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDDDD 262
           S E+++ED +       +  D +    +D   S   S +  S+             D+++
Sbjct: 640 SEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESE-----------DGDENE 688

Query: 263 DDDDDDDDDNIDDDDGDNDHEALGVGDNS 291
           +DD+D+DDD  DD+D DN+ E      +S
Sbjct: 689 EDDEDEDDDEDDDEDEDNESEGSSSSSSS 717



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 15/39 (38%), Positives = 27/39 (69%), Gaps = 3/39 (7%)

Query: 253 SSSYHSDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNS 291
           S S   D++D+DD+D+D++  DD++GD+  +    GD+S
Sbjct: 638 SESEEDDEEDEDDEDEDEEEEDDENGDSSEDG---GDSS 673



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 14/50 (28%), Positives = 25/50 (50%), Gaps = 2/50 (4%)

Query: 237 PFSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDDDDNID--DDDGDNDHEA 284
           P S +   Q             DD+D+D++++DD+N D  +D GD+   +
Sbjct: 627 PKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESS 676


>gi|7657671 upstream binding transcription factor, RNA polymerase I
           isoform a [Homo sapiens]
          Length = 764

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 11/89 (12%)

Query: 203 SSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDDDD 262
           S E+++ED +       +  D +    +D   S   S +  S+             D+++
Sbjct: 677 SEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESE-----------DGDENE 725

Query: 263 DDDDDDDDDNIDDDDGDNDHEALGVGDNS 291
           +DD+D+DDD  DD+D DN+ E      +S
Sbjct: 726 EDDEDEDDDEDDDEDEDNESEGSSSSSSS 754



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 15/39 (38%), Positives = 27/39 (69%), Gaps = 3/39 (7%)

Query: 253 SSSYHSDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNS 291
           S S   D++D+DD+D+D++  DD++GD+  +    GD+S
Sbjct: 675 SESEEDDEEDEDDEDEDEEEEDDENGDSSEDG---GDSS 710



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 14/50 (28%), Positives = 25/50 (50%), Gaps = 2/50 (4%)

Query: 237 PFSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDDDDNID--DDDGDNDHEA 284
           P S +   Q             DD+D+D++++DD+N D  +D GD+   +
Sbjct: 664 PKSSRTTLQSKSESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESS 713


>gi|18093112 ABT1-associated protein [Homo sapiens]
          Length = 851

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 49/235 (20%), Positives = 93/235 (39%), Gaps = 34/235 (14%)

Query: 77  VEHRKEHVRKTIDDLKKVMKNFESRVEFTEDLQKMSDAAGDIVDIREEIKCDFEFKAKHR 136
           ++ +K   +K ID    V K  E++    +  +  +D    I   + +  C  +FK    
Sbjct: 94  IKKKKTQTKKEIDSKNLVEKKKETKKANHKGSENKTDLDNSIGIKKMKTSC--KFKIDSN 151

Query: 137 IAHKPHSKPKTSDIFEADIANDVKSKDLLADKELWARLEELERQEELLGELDSKPDTVIA 196
           I+ K  SK  T          + K K  +      + LEE +R       LDS    ++ 
Sbjct: 152 ISPKKDSKEFTQ--------KNKKEKKNIVQHTTDSSLEEKQRT------LDSGTSEIVK 197

Query: 197 NGEDTTSSEEEKEDRNTNVNAMHQVTDSHTP------CHKD-----------VASSEPFS 239
           +      S+  +E ++     M + +D +        C KD           + S E   
Sbjct: 198 SPR-IECSKTRREMQSVVQLIMTRDSDGYENSTDGEMCDKDALEEDSESVSEIGSDEESE 256

Query: 240 GQVNSQLNCSVNGSSSYHSDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNSIPT 294
            ++ S    S +   S   +++D+D+++D+D++ +DDD  +    L  G  +I T
Sbjct: 257 NEITSVGRASGDDDGSEDDEEEDEDEEEDEDEDSEDDDKSDSGPDLARGKGNIET 311


>gi|42740903 MTERF domain containing 2 [Homo sapiens]
          Length = 381

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 15/26 (57%), Positives = 23/26 (88%)

Query: 259 DDDDDDDDDDDDDNIDDDDGDNDHEA 284
           +DDDD++D+D+DDN +DDD ++D EA
Sbjct: 343 EDDDDEEDNDEDDNDEDDDDEDDDEA 368



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 14/25 (56%), Positives = 20/25 (80%)

Query: 259 DDDDDDDDDDDDDNIDDDDGDNDHE 283
           DD+D+DDDD+DDD  +D+D D D +
Sbjct: 354 DDNDEDDDDEDDDEAEDNDEDEDDD 378



 Score = 38.1 bits (87), Expect = 0.019
 Identities = 14/25 (56%), Positives = 20/25 (80%)

Query: 259 DDDDDDDDDDDDDNIDDDDGDNDHE 283
           D+D+DD+D+DDDD  DD+  DND +
Sbjct: 350 DNDEDDNDEDDDDEDDDEAEDNDED 374



 Score = 37.0 bits (84), Expect = 0.041
 Identities = 13/25 (52%), Positives = 21/25 (84%)

Query: 259 DDDDDDDDDDDDDNIDDDDGDNDHE 283
           DDD++D+D+DD+D  DDD+ D++ E
Sbjct: 345 DDDEEDNDEDDNDEDDDDEDDDEAE 369



 Score = 36.6 bits (83), Expect = 0.054
 Identities = 13/25 (52%), Positives = 21/25 (84%)

Query: 259 DDDDDDDDDDDDDNIDDDDGDNDHE 283
           D+D+DDDD+DDD+  D+D+ ++D E
Sbjct: 355 DNDEDDDDEDDDEAEDNDEDEDDDE 379



 Score = 36.2 bits (82), Expect = 0.070
 Identities = 12/25 (48%), Positives = 22/25 (88%)

Query: 259 DDDDDDDDDDDDDNIDDDDGDNDHE 283
           +D+D+DD+D+DDD+ DDD+ +++ E
Sbjct: 349 EDNDEDDNDEDDDDEDDDEAEDNDE 373



 Score = 36.2 bits (82), Expect = 0.070
 Identities = 12/26 (46%), Positives = 21/26 (80%)

Query: 258 SDDDDDDDDDDDDDNIDDDDGDNDHE 283
           +D+DD+D+DDDD+D+ + +D D D +
Sbjct: 351 NDEDDNDEDDDDEDDDEAEDNDEDED 376



 Score = 36.2 bits (82), Expect = 0.070
 Identities = 12/26 (46%), Positives = 22/26 (84%)

Query: 258 SDDDDDDDDDDDDDNIDDDDGDNDHE 283
           +D+DDDD+DDD+ ++ D+D+ D++ E
Sbjct: 356 NDEDDDDEDDDEAEDNDEDEDDDEEE 381



 Score = 35.8 bits (81), Expect = 0.092
 Identities = 12/25 (48%), Positives = 20/25 (80%)

Query: 257 HSDDDDDDDDDDDDDNIDDDDGDND 281
           + +DDDD+DDD+ +DN +D+D D +
Sbjct: 356 NDEDDDDEDDDEAEDNDEDEDDDEE 380



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 12/31 (38%), Positives = 20/31 (64%)

Query: 251 NGSSSYHSDDDDDDDDDDDDDNIDDDDGDND 281
           N       DDDD+DDD+ +D++ D+DD + +
Sbjct: 351 NDEDDNDEDDDDEDDDEAEDNDEDEDDDEEE 381


>gi|15559211 RE1-silencing transcription factor [Homo sapiens]
          Length = 1097

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 60/262 (22%), Positives = 106/262 (40%), Gaps = 35/262 (13%)

Query: 97  NFESRVEFTEDLQKMSDAAGDIVDIREEIKCD--FEFKAKHRIAHKPHSKPKTSDIFEAD 154
           NF+  VE   + ++ +     + D     KC+  + FK+KH     P    KT D+ +  
Sbjct: 375 NFKKHVELHVNPRQFNCP---VCDYAASKKCNLQYHFKSKH-----PTCPNKTMDVSKVK 426

Query: 155 IANDVKSKDLLADKELWARLEELERQEELLGELDSKPDTVIANGEDTTSSEEEKEDRNTN 214
           +    K +  L D  +     E+E Q ++ G++  K +      E    S+E+K   N +
Sbjct: 427 LKKTKKREADLPDN-ITNEKTEIE-QTKIKGDVAGKKNEKSVKAEKRDVSKEKKPSNNVS 484

Query: 215 VNAMHQVTDSHTPCHKDV-----ASSEPFSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDD 269
           V  +   T       K++     ++SE FS    S+    V+ S S H   +D++     
Sbjct: 485 VIQVTTRTRKSVTEVKEMDVHTGSNSEKFSKTKKSKRKLEVD-SHSLHGPVNDEESSTKK 543

Query: 270 DDNIDDDDGDNDHEALGVGDNSIPTIYFSHTVEPKRVRINTGKNTTLKFSEKKEEAKRKR 329
              ++    +N  E +  GD+              +V  N  +NT +K S KK+    K 
Sbjct: 544 KKKVESKSKNNSQE-VPKGDS--------------KVEENKKQNTCMKKSTKKKTL--KN 586

Query: 330 KNSTGSGHSAQELPTIRTPADI 351
           K+S  S    Q+ P  +  A +
Sbjct: 587 KSSKKSSKPPQKEPVEKGSAQM 608


>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
           precursor [Homo sapiens]
          Length = 513

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 49/179 (27%), Positives = 72/179 (40%), Gaps = 31/179 (17%)

Query: 176 ELERQEELLGELDSKPDTVIANGEDTTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASS 235
           E E  EE  G L   P   + + E +  S+   E++     A    +DS          S
Sbjct: 26  ESEDSEEWKGHLAQAPTPPLESSESSEGSKVSSEEQ-----ANEDPSDS--------TQS 72

Query: 236 EPFSGQVNSQLNCSVNGSSSYHSDDDDDDDDDDDDDNIDDDDGDND------------HE 283
           E   G  + Q    + G  S  +    DD DDD+DD+ DD  GD+D            + 
Sbjct: 73  EEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNS 132

Query: 284 ALGVGDNSIPTIYFSHTVEPKRVRINTGKNTTLKFSEKKEEAKRKRKNS-TGSGHSAQE 341
            LG  ++S  TI  S    P+    ++ ++TT   SE +E     R +S    G S QE
Sbjct: 133 RLGSDEDSDDTIQASEESAPQGQ--DSAQDTT---SESRELDNEDRVDSKPEGGDSTQE 186



 Score = 34.7 bits (78), Expect = 0.20
 Identities = 35/169 (20%), Positives = 66/169 (39%), Gaps = 17/169 (10%)

Query: 158 DVKSKDLLADKELWARLEELERQEELLGEL-DSKPD---TVIANGEDTTSSEEE------ 207
           D  S +   +  L ++    E QEE++ E     PD   + + + ED+ SSEE+      
Sbjct: 334 DGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLS 393

Query: 208 ---KEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDDDDDD 264
               E R    ++    + + +    +    E  S Q   Q + S   S S  S  ++DD
Sbjct: 394 HSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDD 453

Query: 265 DDDDDDDNIDDDDGDNDHEALGVGDNSIPTIYFSHTVEPKRVRINTGKN 313
            D  D     +D    + ++    D  +  I     +E +++ ++   N
Sbjct: 454 SDSQDSSRSKEDSNSTESKSSSEEDGQLKNI----EIESRKLTVDAYHN 498


>gi|217330641 IWS1 homolog [Homo sapiens]
          Length = 819

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 68/349 (19%), Positives = 131/349 (37%), Gaps = 58/349 (16%)

Query: 106 EDLQKMSDAAGDIVDIREEIKCDFEFK--AKHRIAHKPHSKPKTSDIFEADIANDVKSKD 163
           ED+ K   +  +I ++++    D E +   K +I+     +P       +D  N+   K 
Sbjct: 149 EDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQA--SDSENEEPPKP 206

Query: 164 LLADKELWARLEELERQEELLGELDSKPDTVIANGEDTTSSEEEKEDRNTNVNAMHQVTD 223
            ++D E     EEL + +    E +  P    ++ E+    +    D  +     HQ +D
Sbjct: 207 RMSDSES----EELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASD 262

Query: 224 SHT-----PCHKDVASSEPFSGQVNSQLN----------------------CSVNGSSSY 256
           S       P   D  S +P   Q +   N                       S    +S 
Sbjct: 263 SENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPASDSETEDASR 322

Query: 257 HSDDDDDDDDDDDDDNIDDDDGDNDHEALGVGDNSIPTIYF----SHTVEPKRVRINTGK 312
           H    + DDD D ++  +D +  ND       D+ +    F    S   E K+ ++++ +
Sbjct: 323 HKQKPESDDDSDRENKGEDTEMQNDSFH---SDSHMDRKKFHSSDSEEEEHKKQKMDSDE 379

Query: 313 NTTLKFSEKKEEAKRKRKNSTGSGHSAQELPTI---RTPADIYRAFVDVVNGEYVPRKSI 369
           +      E +EE   KRK +  S    +E  +    R  +D   +  D V+         
Sbjct: 380 DE----KEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSD-------- 427

Query: 370 LKSRSRENSVCSDTSESSAAEFDDRRGVLRSISCEEATCSDTSESILEE 418
            KS  RE ++ SD+ E +  E  D++   + +   ++   +  E+++ +
Sbjct: 428 -KSGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENLIAD 475



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 28/99 (28%), Positives = 40/99 (40%), Gaps = 25/99 (25%)

Query: 197 NGEDTTS----SEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNG 252
           +G DT S    SE E  DR   +   H VTDS         + EP +      LN S + 
Sbjct: 38  SGSDTGSVERHSENETSDREDGLPKGHHVTDSE--------NDEPLN------LNASDSE 83

Query: 253 SSSYHSDDDDDDDDDD-------DDDNIDDDDGDNDHEA 284
           S   H   D D + ++       D +N D +   +D E+
Sbjct: 84  SEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSES 122


>gi|16445033 ACRC protein [Homo sapiens]
          Length = 691

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 68/292 (23%), Positives = 105/292 (35%), Gaps = 27/292 (9%)

Query: 200 DTTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSD 259
           D  S + E  D N++        DS  P      S  P     +S +    +  SS  + 
Sbjct: 150 DDNSDDSEAPDDNSD--------DSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNS 201

Query: 260 DDDDDDDDDDDDNIDDDDGDNDHEALGVGDNSIPTIYFSHTVEPKRVRINTGKNTTLKFS 319
           DD  DD+ DD D  DD   D+D       D+ +P      +  P     +         S
Sbjct: 202 DDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPD--DSSDDSEAPDDSS 259

Query: 320 EKKEEAKRKRKNSTGSGHSAQELPTIRTPADIYRAFVDVVNGEYVPRKSILKSRSRENSV 379
           +  E       +S     S+ +       +D   A  D  +    P       +S ++ V
Sbjct: 260 DDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAP-----DDKSDDSDV 314

Query: 380 CSDTSESSAAEFDDRRGVLRSISCEEATCSDTSESILEEEPQENQKKLLPLSVTPEAFSG 439
             D S+ S    DD    L      E  C++   +  EEE  E        +V+    S 
Sbjct: 315 PEDKSDDSDVP-DDNSDDLEVPVPAEDLCNEGQIASDEEELVE-----AAAAVSQHDSSD 368

Query: 440 TVIEKEFVSPSLTPPPAIAHPALPTIPERK----EVLLEASEETGKRVSKFK 487
              E++ +  +L+ PP+    A P + ERK    E      E++GKR SK K
Sbjct: 369 DAGEQD-LGENLSKPPSDPE-ANPEVSERKLPTEEEPAPVVEQSGKRKSKTK 418



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 25/94 (26%), Positives = 38/94 (40%), Gaps = 8/94 (8%)

Query: 200 DTTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSD 259
           D  S + E  D N++        DS  P      S  P     +S+     +  S    D
Sbjct: 140 DDNSDDSEAPDDNSD--------DSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDD 191

Query: 260 DDDDDDDDDDDDNIDDDDGDNDHEALGVGDNSIP 293
           + DD  DD+ DD+ DD+  D+D       D+ +P
Sbjct: 192 NSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVP 225



 Score = 35.8 bits (81), Expect = 0.092
 Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 17/108 (15%)

Query: 196 ANGEDTTSSEEEKEDRNTNVNAMHQVTDSHTP--CHKDVASSEP---FSGQVN-----SQ 245
           ++ ++   + EEK+ +   +N+     D  +P  CH   A  EP    S   N     + 
Sbjct: 81  SDSDEECHTHEEKKAKLLEINS-----DDESPECCHVKPAIQEPPIVISDDDNDDDNGND 135

Query: 246 LNCSVNGSSSYHSDDDDDDDDDDDDDNIDDDDG--DNDHEALGVGDNS 291
           L    + S    + DD+ DD +  DDN DD +   DN  ++    DNS
Sbjct: 136 LEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNS 183



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 24/96 (25%), Positives = 39/96 (40%), Gaps = 2/96 (2%)

Query: 191 PDTVIANGEDTTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSV 250
           PD    + +    + ++  D N++ ++     DS  P  K   S  P     +S +    
Sbjct: 179 PDDNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDS 238

Query: 251 NGSSSYHSDDDDDDD--DDDDDDNIDDDDGDNDHEA 284
           +  S    D  DD +  DD  DD+   DD  +D EA
Sbjct: 239 SDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEA 274



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 25/104 (24%), Positives = 41/104 (39%), Gaps = 7/104 (6%)

Query: 188 DSKPDTVIANGEDTTSSEEEKEDRNTNVNAMHQVTD-----SHTPCHKDVASSEPFSGQV 242
           D+  D+ + +     SS++  +D + + +    V D     S  P      S  P     
Sbjct: 181 DNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSD 240

Query: 243 NSQLNCSVNGSSSYHSDDDDDDD--DDDDDDNIDDDDGDNDHEA 284
           +S+     +  S    D  DD +  DD  DD+   DD  +D EA
Sbjct: 241 DSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEA 284



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 21/88 (23%), Positives = 37/88 (42%), Gaps = 5/88 (5%)

Query: 199 EDTTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHS 258
           +D +   E  +D + + +     +D  +  + D +S +      +S +    +  S    
Sbjct: 170 DDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDD---NSDDSDVPDDKSDDSDVPD 226

Query: 259 DDDDDDD--DDDDDDNIDDDDGDNDHEA 284
           D  DD D  DD  DD+   DD  +D EA
Sbjct: 227 DSSDDSDVPDDSSDDSEAPDDSSDDSEA 254



 Score = 29.6 bits (65), Expect = 6.6
 Identities = 20/83 (24%), Positives = 34/83 (40%), Gaps = 11/83 (13%)

Query: 204 SEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSVNGSSSYHSDDDDD 263
           S+++ +D N N        D   P      S  P     +S+     +  S    D+ DD
Sbjct: 124 SDDDNDDDNGN--------DLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDD 175

Query: 264 D---DDDDDDDNIDDDDGDNDHE 283
               DD+ DD ++ DD+ D+  +
Sbjct: 176 SEAPDDNSDDSDVPDDNSDDSSD 198



 Score = 29.6 bits (65), Expect = 6.6
 Identities = 23/94 (24%), Positives = 37/94 (39%), Gaps = 2/94 (2%)

Query: 191 PDTVIANGEDTTSSEEEKEDRNTNVNAMHQVTDSHTPCHKDVASSEPFSGQVNSQLNCSV 250
           PD    + E    S ++ E  + + +      DS         SS+      +S  +   
Sbjct: 235 PDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEA 294

Query: 251 NGSSSYHSDDDDDDDDDDD--DDNIDDDDGDNDH 282
           +  SS  S+  DD  DD D  +D  DD D  +D+
Sbjct: 295 SDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDN 328



 Score = 29.3 bits (64), Expect = 8.6
 Identities = 26/97 (26%), Positives = 40/97 (41%), Gaps = 9/97 (9%)

Query: 188 DSKPDTVIANGEDTTSSEEEKEDRNTNVNAMHQVTD-SHTPCHKDVASSEPFSGQVNSQL 246
           DS  D+ +   +D++   E  +D + +  A    +D S  P      S  P     +S+ 
Sbjct: 227 DSSDDSDVP--DDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSE- 283

Query: 247 NCSVNGSSSYHSDDDDDDDDDDD--DDNIDDDDGDND 281
               +  SS  S+  DD  DD +  DD  DD D   D
Sbjct: 284 ---ASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPED 317


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.128    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,963,475
Number of Sequences: 37866
Number of extensions: 987447
Number of successful extensions: 10884
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 162
Number of HSP's successfully gapped in prelim test: 229
Number of HSP's that attempted gapping in prelim test: 6789
Number of HSP's gapped (non-prelim): 1845
length of query: 495
length of database: 18,247,518
effective HSP length: 106
effective length of query: 389
effective length of database: 14,233,722
effective search space: 5536917858
effective search space used: 5536917858
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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