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Search of human proteins with 19924097
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19924097 synapsin I isoform Ib [Homo sapiens]
(669 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19924097 synapsin I isoform Ib [Homo sapiens] 1377 0.0
gi|19924099 synapsin I isoform Ia [Homo sapiens] 1361 0.0
gi|19924103 synapsin II isoform IIa [Homo sapiens] 646 0.0
gi|19924101 synapsin II isoform IIb [Homo sapiens] 615 e-176
gi|209413756 synapsin III isoform IIIg [Homo sapiens] 599 e-171
gi|209413752 synapsin III isoform IIIa [Homo sapiens] 595 e-170
gi|209413754 synapsin III isoform IIIc [Homo sapiens] 543 e-154
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 135 1e-31
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 128 2e-29
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 127 3e-29
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 117 4e-26
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 101 3e-21
gi|163965366 nascent polypeptide-associated complex alpha subuni... 99 1e-20
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 99 2e-20
gi|150170670 piccolo isoform 2 [Homo sapiens] 97 4e-20
gi|150378539 piccolo isoform 1 [Homo sapiens] 97 4e-20
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 96 1e-19
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 89 1e-17
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 89 1e-17
gi|110832843 TBP-associated factor 4 [Homo sapiens] 89 1e-17
gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre... 89 1e-17
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 89 1e-17
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 89 1e-17
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 86 8e-17
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 86 8e-17
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 86 8e-17
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 86 1e-16
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] 86 1e-16
gi|192807323 SWI/SNF-related matrix-associated actin-dependent r... 85 2e-16
gi|192807320 SWI/SNF-related matrix-associated actin-dependent r... 85 2e-16
>gi|19924097 synapsin I isoform Ib [Homo sapiens]
Length = 669
Score = 1377 bits (3564), Expect = 0.0
Identities = 669/669 (100%), Positives = 669/669 (100%)
Query: 1 MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPA 60
MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPA
Sbjct: 1 MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPA 60
Query: 61 ASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRVLLVID 120
ASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRVLLVID
Sbjct: 61 ASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRVLLVID 120
Query: 121 EPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKP 180
EPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKP
Sbjct: 121 EPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKP 180
Query: 181 DFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLG 240
DFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLG
Sbjct: 181 DFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLG 240
Query: 241 TEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKT 300
TEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKT
Sbjct: 241 TEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKT 300
Query: 301 YATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTC 360
YATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTC
Sbjct: 301 YATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTC 360
Query: 361 SEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALPR 420
SEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALPR
Sbjct: 361 SEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALPR 420
Query: 421 QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPP 480
QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPP
Sbjct: 421 QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPP 480
Query: 481 LQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGP 540
LQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGP
Sbjct: 481 LQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGP 540
Query: 541 GAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGP 600
GAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGP
Sbjct: 541 GAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGP 600
Query: 601 TRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQL 660
TRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQL
Sbjct: 601 TRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQL 660
Query: 661 KASPAQAQP 669
KASPAQAQP
Sbjct: 661 KASPAQAQP 669
>gi|19924099 synapsin I isoform Ia [Homo sapiens]
Length = 705
Score = 1361 bits (3522), Expect = 0.0
Identities = 661/663 (99%), Positives = 661/663 (99%)
Query: 1 MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPA 60
MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPA
Sbjct: 1 MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPA 60
Query: 61 ASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRVLLVID 120
ASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRVLLVID
Sbjct: 61 ASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRVLLVID 120
Query: 121 EPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKP 180
EPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKP
Sbjct: 121 EPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKP 180
Query: 181 DFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLG 240
DFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLG
Sbjct: 181 DFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLG 240
Query: 241 TEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKT 300
TEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKT
Sbjct: 241 TEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKT 300
Query: 301 YATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTC 360
YATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTC
Sbjct: 301 YATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTC 360
Query: 361 SEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALPR 420
SEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALPR
Sbjct: 361 SEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALPR 420
Query: 421 QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPP 480
QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPP
Sbjct: 421 QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPP 480
Query: 481 LQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGP 540
LQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGP
Sbjct: 481 LQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGP 540
Query: 541 GAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGP 600
GAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGP
Sbjct: 541 GAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGP 600
Query: 601 TRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQL 660
TRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQL
Sbjct: 601 TRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQL 660
Query: 661 KAS 663
S
Sbjct: 661 NKS 663
Score = 58.2 bits (139), Expect = 2e-08
Identities = 63/196 (32%), Positives = 74/196 (37%), Gaps = 45/196 (22%)
Query: 419 PRQRQRDASP-----GRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQ---- 469
P+Q A+P GR S PGA P R PPA P Q GPPQ
Sbjct: 515 PQQPASQAAPPTQGQGRQSRPVAGGPGAPPAAR--------PPASPSPQRQAGPPQATRQ 566
Query: 470 -----PGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAP 524
P P PP GQQ GP PQ+ P P + P + ASQA P
Sbjct: 567 TSVSGPAPPKA-------SGAPPGGQQR---QGP------PQKPPGP-AGPTRQASQAGP 609
Query: 525 -PTQGQGRQSRPVAGGPGAPPAARP-PASPSPQRQAGPPQATRQTSVSGPAPPKASGAPP 582
P G +P GPG PA RP P Q PP AT + GP P+ + +
Sbjct: 610 VPRTGPPTTQQPRPSGPG--PAGRPKPQLAQKPSQDVPPPAT--AAAGGPPHPQLNKSQS 665
Query: 583 GGQQRQGPPQKPPGPA 598
P PP P+
Sbjct: 666 LTNAFNLPEPAPPRPS 681
>gi|19924103 synapsin II isoform IIa [Homo sapiens]
Length = 582
Score = 646 bits (1667), Expect = 0.0
Identities = 345/568 (60%), Positives = 405/568 (71%), Gaps = 32/568 (5%)
Query: 1 MNYLRRRLSDSNFMANLPNGYMTDLQRPQP----PPPPPGAHSPGATPGPGTATAERSSG 56
MN+LRRRLSDS+F+ANLPNGYMTDLQRP+P PPPPPG + A+ P TA+
Sbjct: 2 MNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPERR 61
Query: 57 VAPAASPAA-PSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRV 115
PA++PA P+P S G FFSSLS AVKQT A+A A ++V
Sbjct: 62 PPPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAASAGLV------DAPAPAPAAARKAKV 115
Query: 116 LLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVV 175
LLV+DEPH DWAK F+GKK+ G+ DIKVEQAEFS+LNLVAHA+G ++VDM+VLRNG KVV
Sbjct: 116 LLVVDEPHADWAKCFRGKKVLGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVV 175
Query: 176 RSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRL 235
RS +PDFVLIRQHAF MA N D+R L+IG+QYAG+PS+NSL S+YNFCDKPWVFAQ+V +
Sbjct: 176 RSFRPDFVLIRQHAFGMAENEDFRHLIIGMQYAGLPSINSLESIYNFCDKPWVFAQLVAI 235
Query: 236 HKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVV 295
+K LG E+FPLI+QT+YPNHKEML+ T+PVVVK+GHAHSGMGKVKV+N +DFQDIASVV
Sbjct: 236 YKTLGGEKFPLIEQTYYPNHKEMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVV 295
Query: 296 ALTKTYATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKL 355
ALT+TYATAEPFID+KYD+RVQKIG NYKAYMRTS+SGNWKTNTGSAMLEQIAMSDRYKL
Sbjct: 296 ALTQTYATAEPFIDSKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKL 355
Query: 356 WVDTCSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMA 415
WVDTCSE+FGGLDICAV+A+HGKDG+D+I EV+ SMPLIG+HQ ED+QLI ELV++KM
Sbjct: 356 WVDTCSEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITELVISKMN 415
Query: 416 QALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQ 475
Q L R SP R Q P G L + PP QRPPPQGGP QP G Q
Sbjct: 416 QLL--SRTPALSPQRPLTTQQPQSGTL----KDPDSSKTPP--QRPPPQGGPGQP-QGMQ 466
Query: 476 RQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRP 535
G L R P G PP+ S S +SAPQ+P P T G S
Sbjct: 467 PPGKVLPPRRLPPGPSL-----PPSSS---SSSSSSSSAPQRP---GGPTTHGDAPSSSS 515
Query: 536 VAGGPGAPPAARPPASPSPQRQAGPPQA 563
+ PP A PP P P Q Q+
Sbjct: 516 -SLAEAQPPLAAPPQKPQPHPQLNKSQS 542
Score = 48.5 bits (114), Expect = 2e-05
Identities = 41/129 (31%), Positives = 49/129 (37%), Gaps = 29/129 (22%)
Query: 505 PQRLPSPTSAPQQ-----PASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAG 559
PQR P T PQ P S PP Q P GGPG P +PP P R+
Sbjct: 426 PQR-PLTTQQPQSGTLKDPDSSKTPP------QRPPPQGGPGQPQGMQPPGKVLPPRRLP 478
Query: 560 PPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPA----GPTRQASQA-GPVPRTG 614
P GP+ P +S + PQ+P GP P+ +S A P
Sbjct: 479 P----------GPSLPPSSSS--SSSSSSSAPQRPGGPTTHGDAPSSSSSLAEAQPPLAA 526
Query: 615 PPTTQQPRP 623
PP QP P
Sbjct: 527 PPQKPQPHP 535
Score = 40.8 bits (94), Expect = 0.004
Identities = 35/124 (28%), Positives = 49/124 (39%), Gaps = 9/124 (7%)
Query: 546 ARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQAS 605
+R PA SPQR P T+Q P +S PP QG P +P G P +
Sbjct: 419 SRTPAL-SPQR----PLTTQQPQSGTLKDPDSSKTPPQRPPPQGGPGQPQGMQPPGKVL- 472
Query: 606 QAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASPA 665
P R P + P S + PQ P+ P+++++ P L A P
Sbjct: 473 ---PPRRLPPGPSLPPSSSSSSSSSSSAPQRPGGPTTHGDAPSSSSSLAEAQPPLAAPPQ 529
Query: 666 QAQP 669
+ QP
Sbjct: 530 KPQP 533
Score = 37.0 bits (84), Expect = 0.059
Identities = 26/80 (32%), Positives = 32/80 (40%), Gaps = 18/80 (22%)
Query: 591 PQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKP----------QLAQKP 640
PQ+PP P P A+ A P T P ++ P PA +P P L+Q
Sbjct: 31 PQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSLSQAV 90
Query: 641 SQ--------DVPPPATAAA 652
Q D P PA AAA
Sbjct: 91 KQTAASAGLVDAPAPAPAAA 110
Score = 33.1 bits (74), Expect = 0.85
Identities = 24/65 (36%), Positives = 28/65 (43%), Gaps = 13/65 (20%)
Query: 516 QQPASQAAPPTQGQGRQSRPVAGGPGAPP--AARPPASPSPQRQAGPPQATRQTSVSGPA 573
Q+P Q PP P GPGA AA P ASP P+R+ PP A+ P
Sbjct: 27 QRPEPQQPPP---------PPPPGPGAASASAAPPTASPGPERR--PPPASAPAPQPAPT 75
Query: 574 PPKAS 578
P S
Sbjct: 76 PSVGS 80
Score = 31.2 bits (69), Expect = 3.2
Identities = 22/57 (38%), Positives = 27/57 (47%), Gaps = 6/57 (10%)
Query: 609 PVPRTGPPTTQQPRPSGPGPA-GRPKPQLAQKPSQDVPPPATAAAGGP-PHPQLKAS 663
P P+ PP P P GPG A P A + PPPA+A A P P P + +S
Sbjct: 29 PEPQQPPP----PPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSS 81
>gi|19924101 synapsin II isoform IIb [Homo sapiens]
Length = 478
Score = 615 bits (1586), Expect = e-176
Identities = 312/470 (66%), Positives = 367/470 (78%), Gaps = 19/470 (4%)
Query: 1 MNYLRRRLSDSNFMANLPNGYMTDLQRPQP----PPPPPGAHSPGATPGPGTATAERSSG 56
MN+LRRRLSDS+F+ANLPNGYMTDLQRP+P PPPPPG + A+ P TA+
Sbjct: 2 MNFLRRRLSDSSFIANLPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPERR 61
Query: 57 VAPAASPAA-PSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRV 115
PA++PA P+P S G FFSSLS AVKQT A+A A ++V
Sbjct: 62 PPPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAASAGLV------DAPAPAPAAARKAKV 115
Query: 116 LLVIDEPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVV 175
LLV+DEPH DWAK F+GKK+ G+ DIKVEQAEFS+LNLVAHA+G ++VDM+VLRNG KVV
Sbjct: 116 LLVVDEPHADWAKCFRGKKVLGDYDIKVEQAEFSELNLVAHADGTYAVDMQVLRNGTKVV 175
Query: 176 RSLKPDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRL 235
RS +PDFVLIRQHAF MA N D+R L+IG+QYAG+PS+NSL S+YNFCDKPWVFAQ+V +
Sbjct: 176 RSFRPDFVLIRQHAFGMAENEDFRHLIIGMQYAGLPSINSLESIYNFCDKPWVFAQLVAI 235
Query: 236 HKKLGTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVV 295
+K LG E+FPLI+QT+YPNHKEML+ T+PVVVK+GHAHSGMGKVKV+N +DFQDIASVV
Sbjct: 236 YKTLGGEKFPLIEQTYYPNHKEMLTLPTFPVVVKIGHAHSGMGKVKVENHYDFQDIASVV 295
Query: 296 ALTKTYATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKL 355
ALT+TYATAEPFID+KYD+RVQKIG NYKAYMRTS+SGNWKTNTGSAMLEQIAMSDRYKL
Sbjct: 296 ALTQTYATAEPFIDSKYDIRVQKIGNNYKAYMRTSISGNWKTNTGSAMLEQIAMSDRYKL 355
Query: 356 WVDTCSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMA 415
WVDTCSE+FGGLDICAV+A+HGKDG+D+I EV+ SMPLIG+HQ ED+QLI ELV++KM
Sbjct: 356 WVDTCSEMFGGLDICAVKAVHGKDGKDYIFEVMDCSMPLIGEHQVEDRQLITELVISKMN 415
Query: 416 QALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQG 465
Q L R SP R Q P G L + PP QRPPPQG
Sbjct: 416 QLL--SRTPALSPQRPLTTQQPQSGTL----KDPDSSKTPP--QRPPPQG 457
Score = 42.0 bits (97), Expect = 0.002
Identities = 26/66 (39%), Positives = 28/66 (42%), Gaps = 18/66 (27%)
Query: 459 QRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQP 518
QRP PQ PP P PGP + PP SP P+R P P SA P
Sbjct: 27 QRPEPQQPPPPPPPGPGAAS---------------ASAAPPTASPGPERRPPPASA---P 68
Query: 519 ASQAAP 524
A Q AP
Sbjct: 69 APQPAP 74
Score = 41.2 bits (95), Expect = 0.003
Identities = 30/88 (34%), Positives = 39/88 (44%), Gaps = 19/88 (21%)
Query: 503 PLPQRLPSPTS-APQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGP- 560
P PQ+ P P P ++ AAPPT G + RP PPA+ P P+P G
Sbjct: 29 PEPQQPPPPPPPGPGAASASAAPPTASPGPERRP-------PPASAPAPQPAPTPSVGSS 81
Query: 561 -----PQATRQTS-----VSGPAPPKAS 578
QA +QT+ V PAP A+
Sbjct: 82 FFSSLSQAVKQTAASAGLVDAPAPAPAA 109
Score = 38.1 bits (87), Expect = 0.026
Identities = 36/115 (31%), Positives = 42/115 (36%), Gaps = 33/115 (28%)
Query: 442 LPLGRQTSQQPAGPPAQQRPPPQG--------GPPQPGPGPQRQGPPLQQRPPPQGQQHL 493
LP G T Q P PPP G PP PGP+R RP
Sbjct: 18 LPNGYMTDLQRPEPQQPPPPPPPGPGAASASAAPPTASPGPER-------RP-------- 62
Query: 494 SGLGPPAGSPLPQRLPSPT--SAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAA 546
PPA +P PQ P+P+ S+ SQA T S + P PAA
Sbjct: 63 ----PPASAPAPQPAPTPSVGSSFFSSLSQAVKQTAA----SAGLVDAPAPAPAA 109
Score = 37.0 bits (84), Expect = 0.059
Identities = 26/80 (32%), Positives = 32/80 (40%), Gaps = 18/80 (22%)
Query: 591 PQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKP----------QLAQKP 640
PQ+PP P P A+ A P T P ++ P PA +P P L+Q
Sbjct: 31 PQQPPPPPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSSFFSSLSQAV 90
Query: 641 SQ--------DVPPPATAAA 652
Q D P PA AAA
Sbjct: 91 KQTAASAGLVDAPAPAPAAA 110
Score = 32.0 bits (71), Expect = 1.9
Identities = 26/64 (40%), Positives = 29/64 (45%), Gaps = 19/64 (29%)
Query: 516 QQPASQAAPPTQGQGRQSRPVAGGPGAPPA--ARPPASPSPQRQAGPPQATRQTSVSGPA 573
Q+P Q PP P GPGA A A P ASP P+R+ PP A S PA
Sbjct: 27 QRPEPQQPPP---------PPPPGPGAASASAAPPTASPGPERR--PPPA------SAPA 69
Query: 574 PPKA 577
P A
Sbjct: 70 PQPA 73
Score = 32.0 bits (71), Expect = 1.9
Identities = 15/39 (38%), Positives = 18/39 (46%), Gaps = 1/39 (2%)
Query: 437 PSPGALPLGRQTSQQPAGPPAQQRPPPQGGP-PQPGPGP 474
P PG + A P ++RPPP P PQP P P
Sbjct: 38 PPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTP 76
Score = 31.2 bits (69), Expect = 3.2
Identities = 22/57 (38%), Positives = 27/57 (47%), Gaps = 6/57 (10%)
Query: 609 PVPRTGPPTTQQPRPSGPGPA-GRPKPQLAQKPSQDVPPPATAAAGGP-PHPQLKAS 663
P P+ PP P P GPG A P A + PPPA+A A P P P + +S
Sbjct: 29 PEPQQPPP----PPPPGPGAASASAAPPTASPGPERRPPPASAPAPQPAPTPSVGSS 81
>gi|209413756 synapsin III isoform IIIg [Homo sapiens]
Length = 579
Score = 599 bits (1545), Expect = e-171
Identities = 337/628 (53%), Positives = 412/628 (65%), Gaps = 75/628 (11%)
Query: 1 MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPA 60
MN+LRRRLSDS+FMANLPNGYMTDLQRP +T P + ER A
Sbjct: 1 MNFLRRRLSDSSFMANLPNGYMTDLQRPD-----------SSTSSPASPAMERRHPQPLA 49
Query: 61 ASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRVLLVID 120
AS ++P G FSSLS+A+KQ A + E G + R R+LLVID
Sbjct: 50 ASFSSP------GSSLFSSLSSAMKQAPQATSGLM-EPPGPSTPIVQR----PRILLVID 98
Query: 121 EPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVVRSLKP 180
+ HTDW+KYF GKK++GEI+I+VEQAEFS+LNL A+ GG VDM+V+RNG KVVRS KP
Sbjct: 99 DAHTDWSKYFHGKKVNGEIEIRVEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVVRSFKP 158
Query: 181 DFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKLG 240
DF+L+RQHA+SMA DYRSLVIGLQY G+P+VNSL+SVYNFC KPWVF+Q++++ LG
Sbjct: 159 DFILVRQHAYSMALGEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSLG 218
Query: 241 TEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTKT 300
E+FPL++QTF+PNHK M+++ +PVVVK+GHAH+GMGK+KV+NQ DFQDI SVVA+ KT
Sbjct: 219 PEKFPLVEQTFFPNHKPMVTAPHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAKT 278
Query: 301 YATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDTC 360
YAT E FID+KYD+R+QKIG NYKAYMRTS+SGNWK NTGSAMLEQ+AM++RY+LWVD+C
Sbjct: 279 YATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDSC 338
Query: 361 SEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALPR 420
SE+FGGLDICAV+A+H KDGRD+IIEV+ SSMPLIG+H +ED+QL+ +LVV+KM+Q LP
Sbjct: 339 SEMFGGLDICAVKAVHSKDGRDYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQ-LPM 397
Query: 421 QRQRDASPGRGSHGQ---TPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQP-GPGPQR 476
SP R Q SPG LG Q Q Q RPPPQGGP Q P PQR
Sbjct: 398 PGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQP------QPRPPPQGGPRQAQSPQPQR 451
Query: 477 QGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPV 536
G P QQR PQGQQ LS P +GSP QR SP S AS + P Q
Sbjct: 452 SGSPSQQRLSPQGQQPLS---PQSGSPQQQR--SPGSPQLSRASSGSSPNQ--------- 497
Query: 537 AGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPG 596
A PGA A++P PP R TS +QG K P
Sbjct: 498 ASKPGATLASQPR----------PPVQGRSTS------------------QQGEESKKPA 529
Query: 597 PAGPTRQASQAGPVPRTGPPTTQQPRPS 624
P P SQ+ + T+Q+ PS
Sbjct: 530 PPHPHLNKSQSLTNSLSTSDTSQRGTPS 557
Score = 34.3 bits (77), Expect = 0.38
Identities = 28/90 (31%), Positives = 35/90 (38%), Gaps = 5/90 (5%)
Query: 582 PGGQQRQGPPQKPPGPA-GPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKP 640
PGG P +P P + QA P+ G P + P GP A P+PQ + P
Sbjct: 398 PGGTAPS--PLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSP 455
Query: 641 SQDVPPPATAAAGGPP--HPQLKASPAQAQ 668
SQ P P PQ + SP Q
Sbjct: 456 SQQRLSPQGQQPLSPQSGSPQQQRSPGSPQ 485
Score = 32.7 bits (73), Expect = 1.1
Identities = 31/102 (30%), Positives = 39/102 (38%), Gaps = 6/102 (5%)
Query: 572 PAPPKASGAPPGGQQRQGPPQKPPGPA--GPTRQASQAGPVPRTGPPTTQQPRP--SGPG 627
P P + +P Q K PG A GP Q P P+ GP Q P+P SG
Sbjct: 396 PMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSP 455
Query: 628 PAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQP 669
R PQ Q S P + P PQL + + + P
Sbjct: 456 SQQRLSPQGQQPLSPQSGSPQQQRS--PGSPQLSRASSGSSP 495
>gi|209413752 synapsin III isoform IIIa [Homo sapiens]
Length = 580
Score = 595 bits (1533), Expect = e-170
Identities = 337/629 (53%), Positives = 412/629 (65%), Gaps = 76/629 (12%)
Query: 1 MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPA 60
MN+LRRRLSDS+FMANLPNGYMTDLQRP +T P + ER A
Sbjct: 1 MNFLRRRLSDSSFMANLPNGYMTDLQRPD-----------SSTSSPASPAMERRHPQPLA 49
Query: 61 ASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRVLLVID 120
AS ++P G FSSLS+A+KQ A + E G + R R+LLVID
Sbjct: 50 ASFSSP------GSSLFSSLSSAMKQAPQATSGLM-EPPGPSTPIVQR----PRILLVID 98
Query: 121 EPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVV-RSLK 179
+ HTDW+KYF GKK++GEI+I+VEQAEFS+LNL A+ GG VDM+V+RNG KVV RS K
Sbjct: 99 DAHTDWSKYFHGKKVNGEIEIRVEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVVSRSFK 158
Query: 180 PDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKL 239
PDF+L+RQHA+SMA DYRSLVIGLQY G+P+VNSL+SVYNFC KPWVF+Q++++ L
Sbjct: 159 PDFILVRQHAYSMALGEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSL 218
Query: 240 GTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTK 299
G E+FPL++QTF+PNHK M+++ +PVVVK+GHAH+GMGK+KV+NQ DFQDI SVVA+ K
Sbjct: 219 GPEKFPLVEQTFFPNHKPMVTAPHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAK 278
Query: 300 TYATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDT 359
TYAT E FID+KYD+R+QKIG NYKAYMRTS+SGNWK NTGSAMLEQ+AM++RY+LWVD+
Sbjct: 279 TYATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDS 338
Query: 360 CSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALP 419
CSE+FGGLDICAV+A+H KDGRD+IIEV+ SSMPLIG+H +ED+QL+ +LVV+KM+Q LP
Sbjct: 339 CSEMFGGLDICAVKAVHSKDGRDYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQ-LP 397
Query: 420 RQRQRDASPGRGSHGQ---TPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQP-GPGPQ 475
SP R Q SPG LG Q Q Q RPPPQGGP Q P PQ
Sbjct: 398 MPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQP------QPRPPPQGGPRQAQSPQPQ 451
Query: 476 RQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRP 535
R G P QQR PQGQQ LS P +GSP QR SP S AS + P Q
Sbjct: 452 RSGSPSQQRLSPQGQQPLS---PQSGSPQQQR--SPGSPQLSRASSGSSPNQ-------- 498
Query: 536 VAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPP 595
A PGA A++P PP R TS +QG K P
Sbjct: 499 -ASKPGATLASQPR----------PPVQGRSTS------------------QQGEESKKP 529
Query: 596 GPAGPTRQASQAGPVPRTGPPTTQQPRPS 624
P P SQ+ + T+Q+ PS
Sbjct: 530 APPHPHLNKSQSLTNSLSTSDTSQRGTPS 558
Score = 34.3 bits (77), Expect = 0.38
Identities = 28/90 (31%), Positives = 35/90 (38%), Gaps = 5/90 (5%)
Query: 582 PGGQQRQGPPQKPPGPA-GPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKP 640
PGG P +P P + QA P+ G P + P GP A P+PQ + P
Sbjct: 399 PGGTAPS--PLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSP 456
Query: 641 SQDVPPPATAAAGGPP--HPQLKASPAQAQ 668
SQ P P PQ + SP Q
Sbjct: 457 SQQRLSPQGQQPLSPQSGSPQQQRSPGSPQ 486
Score = 32.7 bits (73), Expect = 1.1
Identities = 31/102 (30%), Positives = 39/102 (38%), Gaps = 6/102 (5%)
Query: 572 PAPPKASGAPPGGQQRQGPPQKPPGPA--GPTRQASQAGPVPRTGPPTTQQPRP--SGPG 627
P P + +P Q K PG A GP Q P P+ GP Q P+P SG
Sbjct: 397 PMPGGTAPSPLRPWAPQIKSAKSPGQAQLGPQLGQPQPRPPPQGGPRQAQSPQPQRSGSP 456
Query: 628 PAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQP 669
R PQ Q S P + P PQL + + + P
Sbjct: 457 SQQRLSPQGQQPLSPQSGSPQQQRS--PGSPQLSRASSGSSP 496
>gi|209413754 synapsin III isoform IIIc [Homo sapiens]
Length = 444
Score = 543 bits (1400), Expect = e-154
Identities = 285/481 (59%), Positives = 353/481 (73%), Gaps = 38/481 (7%)
Query: 1 MNYLRRRLSDSNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPA 60
MN+LRRRLSDS+FMANLPNGYMTDLQRP +T P + ER A
Sbjct: 1 MNFLRRRLSDSSFMANLPNGYMTDLQRPD-----------SSTSSPASPAMERRHPQPLA 49
Query: 61 ASPAAPSPGSSGGGGFFSSLSNAVKQTTAAAAATFSEQVGGGSGGAGRGGAASRVLLVID 120
AS ++P G FSSLS+A+KQ A + E G + R R+LLVID
Sbjct: 50 ASFSSP------GSSLFSSLSSAMKQAPQATSGLM-EPPGPSTPIVQR----PRILLVID 98
Query: 121 EPHTDWAKYFKGKKIHGEIDIKVEQAEFSDLNLVAHANGGFSVDMEVLRNGVKVV-RSLK 179
+ HTDW+KYF GKK++GEI+I+VEQAEFS+LNL A+ GG VDM+V+RNG KVV RS K
Sbjct: 99 DAHTDWSKYFHGKKVNGEIEIRVEQAEFSELNLAAYVTGGCMVDMQVVRNGTKVVSRSFK 158
Query: 180 PDFVLIRQHAFSMARNGDYRSLVIGLQYAGIPSVNSLHSVYNFCDKPWVFAQMVRLHKKL 239
PDF+L+RQHA+SMA DYRSLVIGLQY G+P+VNSL+SVYNFC KPWVF+Q++++ L
Sbjct: 159 PDFILVRQHAYSMALGEDYRSLVIGLQYGGLPAVNSLYSVYNFCSKPWVFSQLIKIFHSL 218
Query: 240 GTEEFPLIDQTFYPNHKEMLSSTTYPVVVKMGHAHSGMGKVKVDNQHDFQDIASVVALTK 299
G E+FPL++QTF+PNHK M+++ +PVVVK+GHAH+GMGK+KV+NQ DFQDI SVVA+ K
Sbjct: 219 GPEKFPLVEQTFFPNHKPMVTAPHFPVVVKLGHAHAGMGKIKVENQLDFQDITSVVAMAK 278
Query: 300 TYATAEPFIDAKYDVRVQKIGQNYKAYMRTSVSGNWKTNTGSAMLEQIAMSDRYKLWVDT 359
TYAT E FID+KYD+R+QKIG NYKAYMRTS+SGNWK NTGSAMLEQ+AM++RY+LWVD+
Sbjct: 279 TYATTEAFIDSKYDIRIQKIGSNYKAYMRTSISGNWKANTGSAMLEQVAMTERYRLWVDS 338
Query: 360 CSEIFGGLDICAVEALHGKDGRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALP 419
CSE+FGGLDICAV+A+H KDGRD+IIEV+ SSMPLIG+H +ED+QL+ +LVV+KM+Q LP
Sbjct: 339 CSEMFGGLDICAVKAVHSKDGRDYIIEVMDSSMPLIGEHVEEDRQLMADLVVSKMSQ-LP 397
Query: 420 RQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGP 479
PG G PSP P Q + A P Q + PQ G PQP P PQ
Sbjct: 398 -------MPG----GTAPSP-LRPWAPQI--KSAKSPGQAQLGPQLGQPQPRPPPQANLS 443
Query: 480 P 480
P
Sbjct: 444 P 444
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 135 bits (340), Expect = 1e-31
Identities = 111/306 (36%), Positives = 127/306 (41%), Gaps = 45/306 (14%)
Query: 405 LIVELVVNKMAQALPRQRQRDASP--------GRGSHG-----QTPSPGALPLGR--QTS 449
L V L+ AQ+L ++ SP GR G +TP P P GR Q
Sbjct: 6 LSVALLALSSAQSLNEDVSQEESPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGG 65
Query: 450 QQPAGPPAQ----QRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPL- 504
Q GPP + + PPPQGG GP P R G P Q PPQG G P G P
Sbjct: 66 NQSQGPPPRPGKPEGPPPQGGNQSQGP-PPRPGKPEGQ--PPQGGNQSQGPPPRPGKPEG 122
Query: 505 --PQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPAS-------PSPQ 555
PQ P +P PP QG G QS+ PG P P P P
Sbjct: 123 PPPQGGNQSQGPPPRPGKPEGPPPQG-GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPG 181
Query: 556 RQAGPP-QATRQTSVSGPAPPKASGAPP-GGQQRQGPPQKPPGPAGPTRQASQA--GPVP 611
+ GPP Q Q+ P P K G PP GG Q QGPP +P P GP Q GP P
Sbjct: 182 KPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPP 241
Query: 612 RTG----PPTTQQPRPSGPGPAGRPK--PQLAQKPSQDVPPPATAAAGGPPHPQ--LKAS 663
G PP + +P P P GRP+ P P Q +PPPA G PP PQ
Sbjct: 242 HPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHR 301
Query: 664 PAQAQP 669
P Q QP
Sbjct: 302 PPQGQP 307
Score = 84.3 bits (207), Expect = 3e-16
Identities = 81/241 (33%), Positives = 97/241 (40%), Gaps = 51/241 (21%)
Query: 419 PRQRQRDASPGRG---SHGQTPSPGALPLGR--QTSQQPAGPPAQ----QRPPPQGG--- 466
PR + + P +G S G P PG P G+ Q Q GPP + + PPPQGG
Sbjct: 73 PRPGKPEGPPPQGGNQSQGPPPRPGK-PEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQS 131
Query: 467 ---PPQPGP--------GPQRQGPPLQ----QRPPPQGQQHLSGLGPPAGSPL---PQRL 508
PP+PG G Q QGPP + + PPPQG G P G P PQ
Sbjct: 132 QGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGG 191
Query: 509 PSPTSAPQQPASQAAPPTQGQGRQSR---PVAGGPGAPPAAR------PPASPSPQRQAG 559
P +P PP QG G QS+ P G P PP+ PP P P + G
Sbjct: 192 NQSQGPPPRPGKPEGPPPQG-GNQSQGPPPRPGKPEGPPSQGGNKPQGPP--PHPGKPQG 248
Query: 560 PPQATRQTSVSGPAPPKASGAPP-GGQQRQ------GPPQ-KPPGPAGPTRQASQAGPVP 611
PP P P + G PP GG +Q G PQ PP P G G P
Sbjct: 249 PPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQPP 308
Query: 612 R 612
+
Sbjct: 309 Q 309
Score = 30.8 bits (68), Expect = 4.2
Identities = 16/47 (34%), Positives = 20/47 (42%), Gaps = 1/47 (2%)
Query: 27 RPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGG 73
+P+ PPP G S G P PG + G + P P PG G
Sbjct: 77 KPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGP-PPRPGKPEG 122
Score = 30.8 bits (68), Expect = 4.2
Identities = 17/47 (36%), Positives = 19/47 (40%), Gaps = 1/47 (2%)
Query: 27 RPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGG 73
+P+ PPP G S G P PG S G P P PG G
Sbjct: 203 KPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGP-PPHPGKPQG 248
Score = 30.8 bits (68), Expect = 4.2
Identities = 21/65 (32%), Positives = 23/65 (35%), Gaps = 8/65 (12%)
Query: 16 NLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSG-------VAPAASPAAPSP 68
N P G +PQ PPP G + P P PG G PA P P P
Sbjct: 234 NKPQGPPPHPGKPQGPPPQEG-NKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPP 292
Query: 69 GSSGG 73
GG
Sbjct: 293 PPQGG 297
Score = 29.6 bits (65), Expect = 9.4
Identities = 16/47 (34%), Positives = 19/47 (40%), Gaps = 1/47 (2%)
Query: 27 RPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGG 73
+P+ PPP G S G P PG G + P P PG G
Sbjct: 119 KPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGP-PPRPGKPEG 164
Score = 29.6 bits (65), Expect = 9.4
Identities = 16/47 (34%), Positives = 19/47 (40%), Gaps = 1/47 (2%)
Query: 27 RPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGG 73
+P+ PPP G S G P PG G + P P PG G
Sbjct: 161 KPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGP-PPRPGKPEG 206
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 128 bits (321), Expect = 2e-29
Identities = 96/264 (36%), Positives = 111/264 (42%), Gaps = 24/264 (9%)
Query: 416 QALPRQRQRDASPGRGSHGQTP-SPGALPLGR--QTSQQPAGPPAQQRPP--PQGGPPQP 470
Q P + P +G ++P SP P G Q QP GPP PP PQG PPQ
Sbjct: 69 QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPP---PPGKPQGPPPQG 125
Query: 471 GPGPQRQGPPLQ-QRPPPQGQQHLSGLGPPAG--SPLPQRLPSPTSAPQQPASQAAPPTQ 527
G PQ PP + Q PPPQG + S PP P PQ P P P PP Q
Sbjct: 126 GNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 185
Query: 528 GQGR-QSRPVAGGPGAPPA----ARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPP 582
G + Q P G P PP +R SP + Q PPQ Q P P K G PP
Sbjct: 186 GGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 245
Query: 583 -GGQQRQGP-----PQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQL 636
GG + QGP PQ PP G Q++++ P GPP + P GP P PQ
Sbjct: 246 QGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQ 305
Query: 637 AQKPSQDVP--PPATAAAGGPPHP 658
Q P P PP G P P
Sbjct: 306 PQAPPAGQPQGPPRPPQGGRPSRP 329
Score = 124 bits (310), Expect = 4e-28
Identities = 110/319 (34%), Positives = 129/319 (40%), Gaps = 64/319 (20%)
Query: 405 LIVELVVNKMAQALPRQRQRDASPGR-GSHGQTPSPGALPLGRQTSQQPAGPPAQQRPP- 462
L V L+ AQ L ++ SP + Q PSP Q +P GPP PP
Sbjct: 6 LSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSP-------QGGNKPQGPPP---PPG 55
Query: 463 -PQGGPPQPGPGPQRQGPPLQ-QRPPPQGQQHLSGLGPPAG--SPLPQRLPSPTSAPQQP 518
PQG PPQ G PQ PP + Q PPPQG + S PP P PQ P P P
Sbjct: 56 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 115
Query: 519 ASQAAPPTQGQGR-QSRPVAGGPGAPPA----ARPPASPSPQRQAGPPQATRQTSVSGPA 573
PP QG R Q P G P PP +R P SP + Q PPQ Q P
Sbjct: 116 GKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPP 175
Query: 574 PPKASGAPP-GGQQRQGPPQ--KPPGPA--GPTRQASQAGPVPRTGPPTT--QQP----- 621
P K G PP GG++ QGPP KP GP G ++SQ+ P GPP QP
Sbjct: 176 PGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPP 235
Query: 622 ---RPSGPGPAGRPKPQLAQKPSQDVPPPATAAAG-----------------------GP 655
+P GP P G KPQ P + PPA + GP
Sbjct: 236 PPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGP 295
Query: 656 P-----HPQLKASPAQAQP 669
P +PQ +P QP
Sbjct: 296 PPPAGGNPQQPQAPPAGQP 314
Score = 32.3 bits (72), Expect = 1.5
Identities = 19/58 (32%), Positives = 22/58 (37%), Gaps = 5/58 (8%)
Query: 16 NLPNGYMTDLQRPQPPPP-----PPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68
N P G +PQ PPP P G PG GP + S +P P P P
Sbjct: 167 NQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPP 224
Score = 31.6 bits (70), Expect = 2.5
Identities = 15/42 (35%), Positives = 17/42 (40%), Gaps = 5/42 (11%)
Query: 27 RPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68
+PQ PPPP PG GP + G P P P P
Sbjct: 46 KPQGPPPP-----PGKPQGPPPQGGNKPQGPPPPGKPQGPPP 82
Score = 31.2 bits (69), Expect = 3.2
Identities = 19/58 (32%), Positives = 22/58 (37%), Gaps = 5/58 (8%)
Query: 16 NLPNGYMTDLQRPQPPPP-----PPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68
N P G +PQ PPP P G PG GP + S +P P P P
Sbjct: 45 NKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP 102
Score = 31.2 bits (69), Expect = 3.2
Identities = 19/58 (32%), Positives = 22/58 (37%), Gaps = 5/58 (8%)
Query: 16 NLPNGYMTDLQRPQPPPP-----PPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68
N P G +PQ PPP P G PG GP + S +P P P P
Sbjct: 106 NQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP 163
Score = 30.4 bits (67), Expect = 5.5
Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 10/56 (17%)
Query: 27 RPQPPPPPPG---------AHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGG 73
+PQ PPPPPG + P P PG + G + + S +P PG G
Sbjct: 229 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSP-PGKPQG 283
Score = 30.0 bits (66), Expect = 7.2
Identities = 16/48 (33%), Positives = 17/48 (35%), Gaps = 6/48 (12%)
Query: 27 RPQPPPPPPGAHSPGATPGPGTAT------AERSSGVAPAASPAAPSP 68
+PQ PPP G G P PG R G P P P P
Sbjct: 96 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPP 143
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 127 bits (319), Expect = 3e-29
Identities = 106/292 (36%), Positives = 125/292 (42%), Gaps = 33/292 (11%)
Query: 404 QLIVELVVNKMAQALPRQRQRDASPGRGSHGQ-TPSPGALPLGR--QTSQQPAGPPAQQR 460
Q + E V + + +L + A P G+ Q PSP P G Q QP GPP
Sbjct: 17 QNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPP--- 73
Query: 461 PP--PQGGPPQPGPGPQRQGPPLQ-QRPPPQGQQHLSGLGPPAG--SPLPQRLPSPTSAP 515
PP PQG PPQ G PQ PP + Q PPPQG + S PP P PQ P P
Sbjct: 74 PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP 133
Query: 516 QQPASQAAPPTQGQGR-QSRPVAGGPGAPPA-----ARPPASPSPQRQAGPPQATRQTSV 569
P PP QG + Q P G P PP +R SP + Q PPQ Q
Sbjct: 134 PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQG 193
Query: 570 SGPAPPKASGAPP-GGQQRQGPPQKPPG-PAGPTRQASQAGPVPRTGPPTTQQPRPSG-- 625
P P K G PP GG + QGPP PPG P GP Q R+ P Q P P G
Sbjct: 194 PPPPPGKPQGPPPQGGNKPQGPP--PPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGN 251
Query: 626 -----PGPAGRPK---PQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQP 669
P P G+P+ PQ KP PPP G PP K+ +++ P
Sbjct: 252 QPQGPPPPPGKPQGPPPQGGNKPQG--PPPPGKPQGPPPQGGSKSRSSRSPP 301
Score = 122 bits (306), Expect = 1e-27
Identities = 94/280 (33%), Positives = 108/280 (38%), Gaps = 40/280 (14%)
Query: 419 PRQRQRDASPGRGSHGQTPSPGALPLG------------RQTSQQPAGPPAQQRPPPQGG 466
P + + P G+ Q P P P G R +P GPP Q PQG
Sbjct: 135 PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGP 194
Query: 467 PPQPG----PGPQR----QGPP---LQQRPPPQGQQHLSGLGPPAGSPL---PQRLPSPT 512
PP PG P PQ QGPP Q PPPQG P G P PQ P
Sbjct: 195 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQ 254
Query: 513 SAPQQPASQAAPPTQGQGR-QSRPVAGGPGAPPA-----ARPPASPSPQRQAGPPQATRQ 566
P P PP QG + Q P G P PP +R SP + Q PPQ Q
Sbjct: 255 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQ 314
Query: 567 TSVSGPAPPKASGAPP-GGQQRQGP-----PQKPPGPAGPTRQASQAGPVPRTGPPTTQQ 620
P P K G PP GG + QGP PQ PP G +++++ P GPP +
Sbjct: 315 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEG 374
Query: 621 PRPSGPGPAGRPKPQLAQKPSQDVP--PPATAAAGGPPHP 658
P GP P PQ Q P P PP G P P
Sbjct: 375 NNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 414
Score = 115 bits (289), Expect = 1e-25
Identities = 103/299 (34%), Positives = 116/299 (38%), Gaps = 52/299 (17%)
Query: 421 QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQ-------QRPP--PQGGPPQPG 471
Q Q P G P G P G +P GPP Q + PP PQG PPQ G
Sbjct: 67 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGG 126
Query: 472 PGPQRQGPP--LQQRPPPQGQQHLSGLGPPAG--SPLPQRLPSPTSAPQQPASQAAPPTQ 527
PQ PP Q PPPQG G PP P PQ S+ P PP Q
Sbjct: 127 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQ 186
Query: 528 G--QGRQSRPVAGGPGAPPAA---RPPASPSPQRQAGPPQATRQTSVSGPAPP-KASGAP 581
G Q + P G P PP +P P P + GPP S S +PP K G P
Sbjct: 187 GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPP 246
Query: 582 P-GGQQRQGPP------QKPP-----GPAGPTRQASQAGPVPRTG---------PPTTQQ 620
P GG Q QGPP Q PP P GP GP P+ G P Q
Sbjct: 247 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQG 306
Query: 621 PRPSG-------PGPAGRPK---PQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQP 669
P P G P P G+P+ PQ KP PPP G PP K+ A++ P
Sbjct: 307 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG--PPPPGKPQGPPPQGGSKSRSARSPP 363
Score = 114 bits (286), Expect = 2e-25
Identities = 100/281 (35%), Positives = 108/281 (38%), Gaps = 43/281 (15%)
Query: 421 QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQ--------QRPP--PQGGPPQP 470
Q Q P G P G P G +P GPP Q + PP PQG PPQ
Sbjct: 128 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQG 187
Query: 471 GPGPQRQGPP--LQQRPPPQGQQHLSGLGPPAG--SPLPQRLPSPTSAPQQPASQAAPPT 526
G PQ PP Q PPPQG G PP P PQ SA P PP
Sbjct: 188 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPP 247
Query: 527 QG--QGRQSRPVAGGPGAPPAA---RPPASPSPQRQAGPPQATRQTSVSGPAPP-KASGA 580
QG Q + P G P PP +P P P + GPP S S +PP K G
Sbjct: 248 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGP 307
Query: 581 PP-GGQQRQGPP------QKPP-----GPAGPTRQASQAGPVPRTG--------PPTTQQ 620
PP GG Q QGPP Q PP P GP GP P+ G PP Q
Sbjct: 308 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQ 367
Query: 621 --PRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQ 659
P+ G P G P P P Q PPA G P PQ
Sbjct: 368 GPPQQEGNNPQG-PPPPAGGNPQQPQAPPAGQPQGPPRPPQ 407
Score = 109 bits (273), Expect = 7e-24
Identities = 91/263 (34%), Positives = 107/263 (40%), Gaps = 39/263 (14%)
Query: 416 QALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQ-QRPPPQGGPPQPGPGP 474
Q P Q + R G+ P P G Q P PP + Q PPPQGG GP P
Sbjct: 160 QGPPPQGDNKSRSSRSPPGKPQGPP--PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 217
Query: 475 --QRQGPPLQ---------------QRPPPQGQQHLSGLGPPAGSPL--PQRLPSPTSAP 515
+ QGPP Q Q PPPQG G PP G P P + + P
Sbjct: 218 PGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 277
Query: 516 QQPASQAAPPTQG--QGRQSRPVAGGPGAPP--AARPPASPSP---QRQAGPPQATRQTS 568
P PP QG + R SR G P PP P P P + Q PPQ +
Sbjct: 278 PPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 337
Query: 569 VSGPAPP-KASGAPPGGQQRQGPPQKPPG-PAGPTRQAS---QAGPVPRTGPPTTQQPRP 623
GP PP K G PP G + + PPG P GP +Q Q P P G P Q P
Sbjct: 338 --GPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP 395
Query: 624 SGPGPAGRPKPQLAQKPSQDVPP 646
+G P G P+P +PS+ PP
Sbjct: 396 AGQ-PQGPPRPPQGGRPSR--PP 415
Score = 99.8 bits (247), Expect = 7e-21
Identities = 82/233 (35%), Positives = 92/233 (39%), Gaps = 26/233 (11%)
Query: 421 QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQ--------QRPP--PQGGPPQP 470
Q Q P G P G P G +P GPP Q + PP PQG PPQ
Sbjct: 190 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQG 249
Query: 471 GPGPQRQGPP--LQQRPPPQGQQHLSGLGPPAG--SPLPQRLPSPTSAPQQPASQAAPPT 526
G PQ PP Q PPPQG G PP P PQ S+ P PP
Sbjct: 250 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPP 309
Query: 527 QG--QGRQSRPVAGGPGAPPAA---RPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAP 581
QG Q + P G P PP +P P P + GPP S S +PP P
Sbjct: 310 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGP 369
Query: 582 PGGQQRQGPPQKPPGPAGPTRQASQAGPVPRT-GPPTTQQPRPSGPGPAGRPK 633
P QQ PQ PP PAG Q QA P + GPP P G P+ P+
Sbjct: 370 P--QQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP----PQGGRPSRPPQ 416
Score = 38.5 bits (88), Expect = 0.020
Identities = 31/84 (36%), Positives = 37/84 (44%), Gaps = 12/84 (14%)
Query: 412 NKMAQALPRQRQRDASPGRGSHGQTP-SPGALPLG--RQTSQQPAGPPAQQRPPPQGGP- 467
NK P + + P GS ++ SP P G +Q P GPP PP G P
Sbjct: 334 NKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPP----PPAGGNPQ 389
Query: 468 -PQPGPGPQRQGPPLQQRPPPQGQ 490
PQ P Q QGPP RPP G+
Sbjct: 390 QPQAPPAGQPQGPP---RPPQGGR 410
Score = 31.6 bits (70), Expect = 2.5
Identities = 18/59 (30%), Positives = 21/59 (35%), Gaps = 6/59 (10%)
Query: 16 NLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTAT------AERSSGVAPAASPAAPSP 68
N P G + +PQ PPP G G P PG + G P P P P
Sbjct: 45 NKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 103
Score = 31.2 bits (69), Expect = 3.2
Identities = 19/58 (32%), Positives = 22/58 (37%), Gaps = 5/58 (8%)
Query: 16 NLPNGYMTDLQRPQPPPP-----PPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68
N P G +PQ PPP P G PG GP + S +P P P P
Sbjct: 66 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP 123
Score = 31.2 bits (69), Expect = 3.2
Identities = 15/42 (35%), Positives = 17/42 (40%), Gaps = 5/42 (11%)
Query: 27 RPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68
+PQ PPPP PG GP + G P P P P
Sbjct: 128 QPQGPPPP-----PGKPQGPPPQGGNKPQGPPPPGKPQGPPP 164
Score = 31.2 bits (69), Expect = 3.2
Identities = 15/42 (35%), Positives = 17/42 (40%), Gaps = 5/42 (11%)
Query: 27 RPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68
+PQ PPPP PG GP + G P P P P
Sbjct: 190 QPQGPPPP-----PGKPQGPPPQGGNKPQGPPPPGKPQGPPP 226
Score = 30.8 bits (68), Expect = 4.2
Identities = 20/59 (33%), Positives = 23/59 (38%), Gaps = 6/59 (10%)
Query: 16 NLPNGYMTDLQRPQPPPP-----PPGAHSPGATPGPGTATAERS-SGVAPAASPAAPSP 68
N P G +PQ PPP P G PG GP +S S +P P P P
Sbjct: 251 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPP 309
Score = 30.0 bits (66), Expect = 7.2
Identities = 20/59 (33%), Positives = 23/59 (38%), Gaps = 6/59 (10%)
Query: 16 NLPNGYMTDLQRPQPPPP-----PPGAHSPGATPGPGTATAERS-SGVAPAASPAAPSP 68
N P G +PQ PPP P G PG GP +S S +P P P P
Sbjct: 127 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPP 185
Score = 30.0 bits (66), Expect = 7.2
Identities = 20/59 (33%), Positives = 23/59 (38%), Gaps = 6/59 (10%)
Query: 16 NLPNGYMTDLQRPQPPPP-----PPGAHSPGATPGPGTATAERS-SGVAPAASPAAPSP 68
N P G +PQ PPP P G PG GP +S S +P P P P
Sbjct: 189 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPP 247
Score = 29.6 bits (65), Expect = 9.4
Identities = 20/61 (32%), Positives = 22/61 (36%), Gaps = 8/61 (13%)
Query: 27 RPQPPPPPPGAHSPGATPGPGTAT------AERSSGVAPAASPAAPSPGSSGGGGFFSSL 80
+PQ PPP G G P PG + G P P P P GG SS
Sbjct: 241 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP--QGGSKSRSSR 298
Query: 81 S 81
S
Sbjct: 299 S 299
Score = 29.6 bits (65), Expect = 9.4
Identities = 18/56 (32%), Positives = 23/56 (41%), Gaps = 10/56 (17%)
Query: 27 RPQPPPPPPG---------AHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGG 73
+PQ PPPPPG + P P PG G + + S +P PG G
Sbjct: 252 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP-PGKPQG 306
Score = 29.6 bits (65), Expect = 9.4
Identities = 18/56 (32%), Positives = 23/56 (41%), Gaps = 10/56 (17%)
Query: 27 RPQPPPPPPG---------AHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGG 73
+PQ PPPPPG + P P PG G + + S +P PG G
Sbjct: 314 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSP-PGKPQG 368
>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
sapiens]
Length = 247
Score = 117 bits (292), Expect = 4e-26
Identities = 87/236 (36%), Positives = 101/236 (42%), Gaps = 40/236 (16%)
Query: 445 GRQTSQQPAGPPAQQRPPPQGGPPQ---PGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAG 501
G+ ++P G QRPPP G PQ P G Q QGPP PPP G P G
Sbjct: 34 GKPEGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPP----PPP---------GKPEG 80
Query: 502 SPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPP 561
P PQ P P PP QG G QS+ G PP PP P + PP
Sbjct: 81 RP-PQGGNQSQGPPPHPGKPERPPPQG-GNQSQ------GTPP---PPGKP----ERPPP 125
Query: 562 QATRQTSVSGPAPPKASGAPP-GGQQRQGPPQKPPGPAGPTRQ------ASQAGPVPRTG 614
Q Q+ P P K PP GG Q QGPP P P GP Q ++++ P G
Sbjct: 126 QGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQG 185
Query: 615 PPTTQQPRPSGPGPAGRPK--PQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQ 668
PP + +P GP P G+P+ P P Q PPA G PP PQ P AQ
Sbjct: 186 PPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAPPAGKPQGPPPPPQGGRPPRPAQ 241
Score = 102 bits (255), Expect = 9e-22
Identities = 80/225 (35%), Positives = 91/225 (40%), Gaps = 28/225 (12%)
Query: 428 PGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQ---PGPGPQRQGPP---- 480
P G+ Q P P P G+ P G Q PPP G P+ P G Q QGPP
Sbjct: 41 PQGGNQPQRPPP---PPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPG 97
Query: 481 LQQRPPPQGQQHLSGLGPPAGS---PLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVA 537
+RPPPQG G PP G P PQ P P PP QG G QS+
Sbjct: 98 KPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQG-GNQSQ--- 153
Query: 538 GGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGP 597
G PP P P PQ + ++ R PP+ G P G G PQ PP P
Sbjct: 154 ---GPPPHPGKPEGPPPQ-EGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPP-P 208
Query: 598 AGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQ 642
AG Q QA P G P P P G P P+P Q+P Q
Sbjct: 209 AGGNPQQPQA---PPAGKPQGPPPPPQGGRP---PRPAQGQQPPQ 247
Score = 89.7 bits (221), Expect = 8e-18
Identities = 67/178 (37%), Positives = 72/178 (40%), Gaps = 20/178 (11%)
Query: 424 RDASPGRGSHGQTPSPGAL----PLGRQTSQQPAGPPAQ-QRPPPQGGPPQPGPGPQRQG 478
R G S G P PG P G SQ PP + +RPPPQGG P P
Sbjct: 81 RPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPP--- 137
Query: 479 PPLQQRPPPQGQQHLSGLGPPAG---SPLPQRLPSPTSAPQQPASQAAPPTQ-GQGRQSR 534
P +RPPPQG G P G P PQ SA P PP Q G Q
Sbjct: 138 PGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGP 197
Query: 535 PVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQ 592
P G P P PPA +PQ+ PP Q GP PP G PP Q Q PPQ
Sbjct: 198 PPPGKPQGP----PPAGGNPQQPQAPPAGKPQ----GPPPPPQGGRPPRPAQGQQPPQ 247
Score = 43.1 bits (100), Expect = 8e-04
Identities = 33/94 (35%), Positives = 41/94 (43%), Gaps = 16/94 (17%)
Query: 578 SGAPPGGQQRQG-PPQKPPGPAG-----PTRQASQA-GPVPRTGPPTTQQPR-------- 622
SG P G + + G PQ+PP P G P + +Q+ GP P G P + P+
Sbjct: 33 SGKPEGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGP 92
Query: 623 PSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPP 656
P PG RP PQ SQ PPP PP
Sbjct: 93 PPHPGKPERPPPQ-GGNQSQGTPPPPGKPERPPP 125
Score = 30.0 bits (66), Expect = 7.2
Identities = 16/43 (37%), Positives = 18/43 (41%), Gaps = 1/43 (2%)
Query: 27 RPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPG 69
+PQ PPP G S G P PG G + P P PG
Sbjct: 56 KPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGP-PPHPG 97
Score = 29.6 bits (65), Expect = 9.4
Identities = 15/48 (31%), Positives = 18/48 (37%), Gaps = 6/48 (12%)
Query: 27 RPQPPPPPPGAHS------PGATPGPGTATAERSSGVAPAASPAAPSP 68
+P+ PPP G S PG GP + G P P P P
Sbjct: 161 KPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPP 208
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 101 bits (251), Expect = 3e-21
Identities = 80/278 (28%), Positives = 115/278 (41%), Gaps = 40/278 (14%)
Query: 412 NKMAQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQR---PPPQGGPP 468
++ A PR+RQ++ SP RG ++PSP P R+ S PA PP ++R PPP+ P
Sbjct: 526 SRSASPSPRKRQKETSP-RGRRRRSPSPP--PTRRRRSPSPAPPPRRRRTPTPPPRRRTP 582
Query: 469 QP-----GPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAA 523
P P P+R PP+Q+R P PP P P+R SP+ P++ S +
Sbjct: 583 SPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPP---PPPKRRASPSPPPKRRVSHSP 639
Query: 524 PPTQGQG----RQSRPVAG----GPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPP 575
PP Q R+S ++ G + R SP P ++ P R S PP
Sbjct: 640 PPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPP 699
Query: 576 KASGAPPGGQQRQGP---------------PQKPPGPAGPTRQASQAGPVPRTGPPTTQQ 620
GA Q+RQ P P+K A P+ Q+ + R+ +
Sbjct: 700 VRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRS---VSGS 756
Query: 621 PRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHP 658
P P+ P P P +Q PS + P P P
Sbjct: 757 PEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTP 794
Score = 61.6 bits (148), Expect = 2e-09
Identities = 61/262 (23%), Positives = 97/262 (37%), Gaps = 52/262 (19%)
Query: 420 RQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGP 479
+Q D+ S + P + G ++ P P P+ + P +R+
Sbjct: 490 QQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRS 549
Query: 480 PLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGG 539
P PPP ++ P+ +P P+R +PT P++
Sbjct: 550 P---SPPPTRRRR-----SPSPAPPPRRRRTPTPPPRRRT-------------------- 581
Query: 540 PGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAG 599
P PP R SPSP+R + P Q S P P + + +PP +R+ P P
Sbjct: 582 PSPPPRRR---SPSPRRYSPPIQRRYSPS---PPPKRRTASPPPPPKRRASPSPP----- 630
Query: 600 PTRQASQAGPVPRTGPPTTQQPRPS-------GPGP------AGRPKPQLAQKPSQDVPP 646
P R+ S + P + P T++ PS G P A P+P PS
Sbjct: 631 PKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRA 690
Query: 647 PATAAAGGPPHPQLKASPAQAQ 668
P T+++ P +SP + Q
Sbjct: 691 PQTSSSPPPVRRGASSSPQRRQ 712
Score = 58.9 bits (141), Expect = 1e-08
Identities = 57/237 (24%), Positives = 81/237 (34%), Gaps = 65/237 (27%)
Query: 419 PRQRQRDASPGRGS----HGQTPSPGALPLGRQTSQQPAGPP--AQQRPPPQGGPPQPGP 472
P R+R SP R S +PSP P R+T+ P P A PPP+ P
Sbjct: 584 PPPRRRSPSPRRYSPPIQRRYSPSP---PPKRRTASPPPPPKRRASPSPPPKRRVSHSPP 640
Query: 473 GPQRQGPPLQQRPPPQGQQHLSGLGPP-----AGSPLPQRLPSPTSAPQQPASQAAPPTQ 527
QR P ++R P +H G P A SP P + SP+ P+ P + ++PP
Sbjct: 641 PKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPV 700
Query: 528 GQGRQS---------------------------------------------------RPV 536
+G S P
Sbjct: 701 RRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPA 760
Query: 537 AGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQK 593
A P APP+ SPS P ++ P+PP+ S GG++++ K
Sbjct: 761 AKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDK 817
Score = 54.7 bits (130), Expect = 3e-07
Identities = 68/291 (23%), Positives = 110/291 (37%), Gaps = 53/291 (18%)
Query: 420 RQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQ-QRPPPQGGPPQPG--PGPQR 476
R+R+R ++ GS + S + ++ ++ + PP + +R P PP+ P P
Sbjct: 346 RRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPA 405
Query: 477 QGPPLQQRPPPQGQQHLS-----GLGP------------------PAGSPLPQRLPSPTS 513
PP + P Q + + + P P+ +P P+++ S
Sbjct: 406 TPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSES 465
Query: 514 APQQPASQAAPPT-------QGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQ 566
+ AA + + Q +QS +G + RP S + G R+
Sbjct: 466 EEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVG---RRRR 522
Query: 567 TSVSGPAPPKASGAPPGGQQRQGP---PQKPPGPAGPTRQASQAGPVP-----RTGPPTT 618
S S A P +P Q+ P ++ P P PTR+ P P RT P
Sbjct: 523 HSPSRSASP----SPRKRQKETSPRGRRRRSPSPP-PTRRRRSPSPAPPPRRRRTPTPPP 577
Query: 619 QQPRPSGPGPAGRPKPQLAQKPSQ----DVPPPATAAAGGPPHPQLKASPA 665
++ PS P P P+ P Q PPP A PP P+ +ASP+
Sbjct: 578 RRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPS 628
Score = 52.0 bits (123), Expect = 2e-06
Identities = 57/233 (24%), Positives = 85/233 (36%), Gaps = 66/233 (28%)
Query: 419 PRQRQRDASPGRGSHGQTPS---PGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQ 475
PR R R S R + ++PS P R S P P+ P+ P P+
Sbjct: 276 PRSRSRSKSRSR-TRSRSPSHTRPRRRHRSRSRSYSPRRRPS----------PRRRPSPR 324
Query: 476 RQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRP 535
R+ PP + PPP+ ++ S P + + R S
Sbjct: 325 RRTPPRRMPPPPRHRRSRS------------------------------PVRRRRRSSAS 354
Query: 536 VAGGPGAPPAAR---PPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQ 592
++G + ++R PP P P+R + PP+ TR+ S S +PP + R PP
Sbjct: 355 LSGSSSSSSSSRSRSPPKKP-PKRTSSPPRKTRRLS--------PSASPPRRRHRPSPPA 405
Query: 593 KPPGPA--GPTRQAS--------QAGPVPRTGPPTTQQPRPSGPGPAGRPKPQ 635
PP PT Q S P +G T + P+ PKP+
Sbjct: 406 TPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPR 458
Score = 46.6 bits (109), Expect = 7e-05
Identities = 70/300 (23%), Positives = 116/300 (38%), Gaps = 57/300 (19%)
Query: 399 QDEDKQLIVELVVNKMAQALPRQRQRDASPGRG-SHGQTPSPGALPLGRQTSQQPAGPPA 457
QDEDK + + ++ +R+R SP R S +P + P+ R+ + + P
Sbjct: 147 QDEDK----DKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSP- 201
Query: 458 QQRPPPQGGPPQPGPGPQRQGPPLQQRP----PPQGQQHLSG---LGPPAGSPLPQ-RLP 509
R + P P P + + P L + P Q+ S L P P+P+ + P
Sbjct: 202 --RHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEP 259
Query: 510 SPTSAPQQ--------PASQAAPPTQGQGRQSRPVAGGPGAPPAAR-----PPASPSPQR 556
SP ++ P S++ ++ + R P P +R P PSP+R
Sbjct: 260 SPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRR 319
Query: 557 QAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRT-GP 615
+ P + T PP+ PP ++ + P ++ + +S + R+ P
Sbjct: 320 RPSPRRRT---------PPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSP 370
Query: 616 PTTQQPRPSGP-------GPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQ 668
P R S P P+ P P+ +PS PPAT P P+ + SP Q
Sbjct: 371 PKKPPKRTSSPPRKTRRLSPSASP-PRRRHRPS----PPAT------PPPKTRHSPTPQQ 419
Score = 45.1 bits (105), Expect = 2e-04
Identities = 62/282 (21%), Positives = 97/282 (34%), Gaps = 65/282 (23%)
Query: 419 PRQRQRDASPG----RGSHGQTPSPGALPLGRQTSQQP---AGPPAQQRPPPQGGPPQPG 471
PR+R R + P + H TP + S P +G + + + P P
Sbjct: 395 PRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPA 454
Query: 472 PGPQR---------------QGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQ 516
P P++ +QQR + Q S + S P +
Sbjct: 455 PKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKN 514
Query: 517 ---------QPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQT 567
P+ A+P + + +++ P R P+ P +R+ P
Sbjct: 515 GEVGRRRRHSPSRSASPSPRKRQKETSPRGR------RRRSPSPPPTRRRRSP------- 561
Query: 568 SVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPG 627
PAP PP ++ PP + P+ P R+ S P PR P Q+ P
Sbjct: 562 ---SPAP------PPRRRRTPTPPPRRRTPSPPPRRRS---PSPRRYSPPIQRRYSPSPP 609
Query: 628 PAGR-----PKPQLAQKPSQDVPPPATAAAGGPPHPQLKASP 664
P R P P+ PS PPP + PP P+ ++SP
Sbjct: 610 PKRRTASPPPPPKRRASPS---PPPKRRVSHSPP-PKQRSSP 647
Score = 31.6 bits (70), Expect = 2.5
Identities = 20/70 (28%), Positives = 28/70 (40%), Gaps = 6/70 (8%)
Query: 6 RRLSDSNFMANLPNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAA 65
RR+S S ++ P ++P PP P + SP P + S P SP+
Sbjct: 745 RRVSSSRSVSGSPE---PAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKS---PTPSPSP 798
Query: 66 PSPGSSGGGG 75
P GGG
Sbjct: 799 PRNSDQEGGG 808
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 99.0 bits (245), Expect = 1e-20
Identities = 88/301 (29%), Positives = 106/301 (35%), Gaps = 47/301 (15%)
Query: 406 IVELVVNKMAQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAG---PPAQQRPP 462
+V L K A P +Q A S + P G S P G PPA P
Sbjct: 890 VVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPS 949
Query: 463 PQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGP----PAGSPLPQRL--PSPTSAPQ 516
P+GGP P P PP P P+G GP P G+P P PSP P
Sbjct: 950 PKGGPATPSP-KWAPTPPAATPPSPKG-------GPATPSPKGAPTPPAATPPSPKGGPA 1001
Query: 517 QPASQAAP-------PTQGQGRQSRPVAGGPGAPPAARPP-------ASPSPQRQAGPPQ 562
P+ + AP P+ + P G PPAA PP A+P P+ P
Sbjct: 1002 TPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPA 1061
Query: 563 ATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPV------------ 610
AT + GPA P GAP PP GPA P+ + + P
Sbjct: 1062 ATLPSPKGGPATPSLKGAPT--PPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLAT 1119
Query: 611 -PRTGPPTTQQPRPSGP-GPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQ 668
P G PTT P P G P P+ A PP PP +PA
Sbjct: 1120 PPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1179
Query: 669 P 669
P
Sbjct: 1180 P 1180
Score = 94.7 bits (234), Expect = 2e-19
Identities = 85/266 (31%), Positives = 101/266 (37%), Gaps = 41/266 (15%)
Query: 430 RGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQG 489
+G P GA T P G A PPP+G P P P L PPP+G
Sbjct: 1114 KGGLATPPHKGAPTTPAATPPSPKGGLAT--PPPKGAPTTPAATPPSPKGGLAT-PPPKG 1170
Query: 490 QQHLSGLGPPAGSPLPQ---RLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAA 546
+ P A P P+ PSP AP PA A P +G + P G PAA
Sbjct: 1171 ----APTTPAATPPSPKGGLATPSPKGAPTTPA---ATPPSPKGGLATPSPKGAPTTPAA 1223
Query: 547 RPP------ASPSPQRQAGPPQATRQTSVSGPA--PPKASGAPPGGQQRQ------GPPQ 592
PP A+PSP+ P AT + GPA PPK + PP PP
Sbjct: 1224 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPH 1283
Query: 593 K---------PPGP-AGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQ 642
K PP P GP + P P P + + P P P G P P PS
Sbjct: 1284 KGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343
Query: 643 DVPP--PAT--AAAGGPPHPQLKASP 664
P PAT ++ GGP P K P
Sbjct: 1344 KGTPTLPATTPSSKGGPTTPSSKEGP 1369
Score = 93.6 bits (231), Expect = 5e-19
Identities = 80/264 (30%), Positives = 96/264 (36%), Gaps = 36/264 (13%)
Query: 428 PGRGSHGQTPSPGAL----PLGRQTSQQPAG---PPAQQRPPPQGGP----PQPGPGPQR 476
P S P+P A P G + P G PPA P P+GGP P+ P P
Sbjct: 954 PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPA 1013
Query: 477 QGPPLQQRPP-----PQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGR 531
PP + P P+G PP+ P P P AP PA+ P +G
Sbjct: 1014 VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP---KGG 1070
Query: 532 QSRPVAGGPGAPPAARPP------ASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQ 585
+ P G PPAA PP A+PSP+ PP AT + G A P GAP
Sbjct: 1071 PATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT-- 1128
Query: 586 QRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVP 645
P PP P G A P P+ P T PS G P P+ A P
Sbjct: 1129 ----PAATPPSPKG-----GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1179
Query: 646 PPATAAAGGPPHPQLKASPAQAQP 669
P P +PA P
Sbjct: 1180 PSPKGGLATPSPKGAPTTPAATPP 1203
Score = 88.2 bits (217), Expect = 2e-17
Identities = 85/261 (32%), Positives = 99/261 (37%), Gaps = 42/261 (16%)
Query: 430 RGSHGQTPSP-GALPLGRQTSQQPAGPPAQQRPPPQGGP-------PQPGPGPQRQGPPL 481
+GS TP P GA T P G PA P P+G P P P GP P L
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPSPKGSPAAT-PLPKGAPTTPAATLPSPKGGPAT--PSL 1076
Query: 482 QQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPG 541
+ P P S G PA PSP AP PA A PP+ G + P G P
Sbjct: 1077 KGAPTPPAATPPSPKGGPA-------TPSPKGAPMPPA--ATPPSPKGGLATPPHKGAP- 1126
Query: 542 APPAARPP------ASPSPQRQAGPPQATRQTSVSGPAPPKASGAPP----------GGQ 585
PAA PP A+P P+ P AT + G A P GAP GG
Sbjct: 1127 TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1186
Query: 586 QRQGPPQKPPGPAG--PTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQD 643
P P PA P+ + A P P+ P T PS G P P+ A
Sbjct: 1187 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1246
Query: 644 VPPPATAAAGGPPHPQLKASP 664
PP + GGP P K +P
Sbjct: 1247 TPP---SPKGGPATPPPKGAP 1264
Score = 83.6 bits (205), Expect = 5e-16
Identities = 88/290 (30%), Positives = 109/290 (37%), Gaps = 44/290 (15%)
Query: 415 AQALPRQRQRDASPG-RGSHGQTPSPGALPLGRQTSQQPAG---PPAQQRPPPQGG---P 467
A LP + A+P +G+ + P G + P G PPA P P+GG P
Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120
Query: 468 PQPG-PGPQRQGPPLQQ----RPPPQGQQHLSGLGPPAGSPLPQ---RLPSPTSAPQQPA 519
P G P PP + PPP+G + P A P P+ P P AP PA
Sbjct: 1121 PHKGAPTTPAATPPSPKGGLATPPPKG----APTTPAATPPSPKGGLATPPPKGAPTTPA 1176
Query: 520 SQAAPPTQGQGRQSRPVAGGPGAPPAARPP------ASPSPQRQAGPPQATRQTSVSGPA 573
A P +G + P G PAA PP A+PSP+ P AT + G A
Sbjct: 1177 ---ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA 1233
Query: 574 PPKASG----------APPGGQQRQGPPQKPPGPAG--PTRQASQAGPVPRTGPPTTQQP 621
P G +P GG P P PA P+ + A P P G P
Sbjct: 1234 TPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATP-PHKGAPNPAVV 1292
Query: 622 RPSGP--GPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQP 669
P P GPA P P+ A P PP + G PP PA P
Sbjct: 1293 TPPSPKGGPATSP-PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPP 1341
Score = 82.4 bits (202), Expect = 1e-15
Identities = 68/214 (31%), Positives = 79/214 (36%), Gaps = 21/214 (9%)
Query: 464 QGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLG---PPAGSPLPQ--RLPSPTSAPQQP 518
QG P P + P P LS G PP +P P LP P P P
Sbjct: 844 QGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP 903
Query: 519 ASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKAS 578
A + AP + P AP PASPSP+ PP AT + GPA P
Sbjct: 904 APKQAPALSMTSSSPKKARATP-APKGI--PASPSPKGAPTPPAATPPSPKGGPATPSPK 960
Query: 579 GAPPGGQQRQGPPQKPPGP-AGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLA 637
AP P PP P GP + + P P P + + P+ P P G P P
Sbjct: 961 WAP------TPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAV 1014
Query: 638 QKPSQDVPPPAT---AAAGGPP---HPQLKASPA 665
PS P AT A PP P K SPA
Sbjct: 1015 TPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA 1048
Score = 77.0 bits (188), Expect = 5e-14
Identities = 77/264 (29%), Positives = 95/264 (35%), Gaps = 31/264 (11%)
Query: 428 PGRGSHGQTPSPGALPLGRQTSQQPAGPP---AQQRPPPQGGPPQPGPGPQRQGPPLQQR 484
P +G+ + P G + P G P A P P+GG P P P
Sbjct: 1144 PPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1203
Query: 485 PPPQGQQHLSGLGPP----AGSPLPQ---RLPSPTSAPQQPASQAAPPTQGQGRQSRPVA 537
P G S G P A P P+ PSP AP PA A PP+ G + P
Sbjct: 1204 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA--ATPPSPKGGPATPPPK 1261
Query: 538 GGPGAPPAARPP------ASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPP 591
G P PPAA PP A+P + P T + GPA GAP P
Sbjct: 1262 GAP-TPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAP------TPPA 1314
Query: 592 QKPPGPAG-PTRQASQAGPVPRTGPPTTQQPRPSGPG--PAGRPKPQLAQKPSQDVPPPA 648
PP P G P + P P P + + P+ P P+ + P PP A
Sbjct: 1315 ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAA 1374
Query: 649 TAAAGGPP---HPQLKASPAQAQP 669
T + G P P K PA P
Sbjct: 1375 TPSHKGGPAMTPPSPKRGPAIPSP 1398
Score = 73.9 bits (180), Expect = 4e-13
Identities = 73/240 (30%), Positives = 93/240 (38%), Gaps = 20/240 (8%)
Query: 436 TPSP-GALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLS 494
TPSP GA T P G A P P+G P P P L P P+G
Sbjct: 1188 TPSPKGAPTTPAATPPSPKGGLAT--PSPKGAPTTPAATPPSPKGGLAT-PSPKGAPTTP 1244
Query: 495 GLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSP 554
PP+ P P P AP PA A PP+ G + P G P PA P SP
Sbjct: 1245 AATPPSPKGGPAT-PPPKGAPTPPA--ATPPSLKGGLATPPHKGAPN--PAVVTPPSPKG 1299
Query: 555 QRQAGPPQ-ATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAG-----PTRQASQAG 608
PP+ A + + P+P + G PP P PP P G T +S+ G
Sbjct: 1300 GPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGG 1359
Query: 609 PVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQ-LKASPAQA 667
P T P + + P P P+ + P + PS P + G P P + SP +A
Sbjct: 1360 P---TTPSSKEGPTPPAATPSHKGGPAMT-PPSPKRGPAIPSPKGDPTSPAVIPLSPKKA 1415
Score = 71.6 bits (174), Expect = 2e-12
Identities = 75/269 (27%), Positives = 97/269 (36%), Gaps = 55/269 (20%)
Query: 443 PLGRQTSQQPAGPP---AQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPP 499
P G + P G P A P P+GG P P +G P P + PP
Sbjct: 1205 PKGGLATPSPKGAPTTPAATPPSPKGGLATPSP----KGAPTTPAATPPSPKGGPATPPP 1260
Query: 500 AGSPLPQRLPSPT------SAPQQPASQAA---PPTQGQGRQSRPVAGGPGAPPAARPPA 550
G+P P P+ + P + A A PP+ G + P G P PPAA PP+
Sbjct: 1261 KGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAP-TPPAATPPS 1319
Query: 551 ------SPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQA 604
+P P+ PP T + P P + + GG P GP P
Sbjct: 1320 PKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTT---PSSKEGPTPPAATP 1376
Query: 605 SQAG------PVPRTGP--------PTTQQPRPSGP--GPAGRPKPQLAQKPSQ-DVPPP 647
S G P P+ GP PT+ P P PA + A PS+ D+ PP
Sbjct: 1377 SHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPP 1436
Query: 648 A------------TAAAGGPPHPQLKASP 664
A +A GGP P K P
Sbjct: 1437 AVTPVSLKKAPATSAPKGGPATPSSKGDP 1465
Score = 65.5 bits (158), Expect = 2e-10
Identities = 74/275 (26%), Positives = 99/275 (36%), Gaps = 27/275 (9%)
Query: 413 KMAQALPRQRQRDASPGRGSHGQTPSPGALPLGRQ---TSQQPAGPPAQQRPPPQGGPPQ 469
K A A P R+ A+P +G TP P P+ + + P G PA P +G P
Sbjct: 1413 KKAPATPVTREGAATPSKGD--LTP-PAVTPVSLKKAPATSAPKGGPAT--PSSKGDPTL 1467
Query: 470 PG--PGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSP-LPQRLPS-PTSAPQQPASQAAP- 524
P P ++ P +Q + P G+P LP +PS P P P+S+ P
Sbjct: 1468 PAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPI 1527
Query: 525 -PTQGQGRQSRPVAGGPGA---PPAA------RPPASPSPQRQAGPPQATRQTSVSGPAP 574
PT + P P PPA + PA P+P+ P + +S P
Sbjct: 1528 APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTP 1587
Query: 575 PKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKP 634
GAP + P P P + P P GP T P P G P P
Sbjct: 1588 STYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPAT---PAPKGT-PTSPPVT 1643
Query: 635 QLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQP 669
+ K S P T G K PA+ P
Sbjct: 1644 PSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGP 1678
Score = 63.5 bits (153), Expect = 6e-10
Identities = 76/291 (26%), Positives = 97/291 (33%), Gaps = 54/291 (18%)
Query: 430 RGSHGQTPSPGALPLGRQTSQQPAGPPA--QQRPPPQGGPPQP----GPGP------QRQ 477
+GS G P GA T P G P P +GGP P GP P +
Sbjct: 1321 KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG 1380
Query: 478 GPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLP-SPTSAPQQPASQAAPPTQGQGRQSRPV 536
GP + P +G S G P P +P SP AP P ++ T +G + P
Sbjct: 1381 GPAMTPPSPKRGPAIPSPKGDPTS---PAVIPLSPKKAPATPVTREGAATPSKGDLTPPA 1437
Query: 537 A---------------GGPGAPPAARPP-----ASPSPQRQAGPPQ-ATRQTSVSGPAPP 575
GGP P + P PSP+ P Q AT + PA P
Sbjct: 1438 VTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATP 1497
Query: 576 KASGAPPGGQQRQGPPQKPPG-------PAGPT------RQASQAGPVPRTGPPTTQQPR 622
GAP P++ P P PT + + P PP P
Sbjct: 1498 APMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPS 1557
Query: 623 PSGPGPAGRPKPQLAQKPSQDV--PPPATAAA--GGPPHPQLKASPAQAQP 669
P PK A S++ PP T + G P +L PA P
Sbjct: 1558 PKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSP 1608
Score = 51.6 bits (122), Expect = 2e-06
Identities = 66/281 (23%), Positives = 87/281 (30%), Gaps = 65/281 (23%)
Query: 437 PSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPG--PGPQRQGP--PLQQRPPPQGQQH 492
PSP P +Q + + A P P G P P P ++ P P +R P
Sbjct: 1473 PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTAT 1532
Query: 493 LSGLGPPAGS-------PLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGA--- 542
L PA P +PSP P P + AP T S P A P
Sbjct: 1533 LLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKG 1592
Query: 543 -----------------------PPAARPP------ASPSPQRQAGPPQATRQTSVSGPA 573
PPA PP A+P+P+ P T + P
Sbjct: 1593 APSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPT 1652
Query: 574 PPKA---------SGAPPGGQQRQGP-----------PQKPPGPAGPTRQASQAGPVPRT 613
P + A G ++GP P+ P PTR+ Q T
Sbjct: 1653 SPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSAT 1712
Query: 614 GPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGG 654
PP P PS + P +A P V ++ A G
Sbjct: 1713 SPPIC--PDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKG 1751
Score = 47.4 bits (111), Expect = 4e-05
Identities = 60/235 (25%), Positives = 77/235 (32%), Gaps = 18/235 (7%)
Query: 442 LPLGRQTSQQ-PAGPPAQQRPPPQG----GPPQPGPGPQRQGPPLQQRPPPQ---GQQHL 493
LPL S+ P P Q P P P P PP P + G H
Sbjct: 698 LPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHT 757
Query: 494 SGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPS 553
S L P A SP + P+ S AS T P G P + P P+
Sbjct: 758 SALAPVASSP--KECPTEDSGASATASSKGTLTY---LADSPSPLGVSVSPQTKRP--PT 810
Query: 554 PQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRT 613
+ AGP S S +P +AS P QG P PT + + P P
Sbjct: 811 KKGSAGPDTPIGNLS-SPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSA 869
Query: 614 GPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQ 668
P + P+ P P P + P P A P +SP +A+
Sbjct: 870 VTPLS--PKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKAR 922
Score = 41.6 bits (96), Expect = 0.002
Identities = 58/233 (24%), Positives = 84/233 (36%), Gaps = 45/233 (19%)
Query: 470 PGPGPQRQGPPLQQRPPPQGQQHL----------SGLGPPAGSPLPQRLPSPTSAPQQPA 519
PG + Q+ P PQ + + + LG P + P P+P P A
Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61
Query: 520 SQAAP-PT--------------QGQGRQSRPVAGGPGAPP----AARPPASPSPQRQAGP 560
+QA+P P+ Q + P+ P AP PP SP+ A P
Sbjct: 62 NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASP 121
Query: 561 PQA-TRQTSVSGPAPPKASGAPPGGQQRQG--PPQKPPGPAGPTRQASQAG-------PV 610
A T + + S AP P Q+ PP P P+ +++G P+
Sbjct: 122 MIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSP--PSVAVAESGSVITLSAPI 179
Query: 611 PRTGPPTTQQPRPSG--PGPAGRPKPQ--LAQKPSQDVPPPATAAAGGPPHPQ 659
+ P T PS P P G P P ++ P V P A+ +G PQ
Sbjct: 180 APSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQ 232
Score = 38.9 bits (89), Expect = 0.016
Identities = 70/311 (22%), Positives = 95/311 (30%), Gaps = 84/311 (27%)
Query: 413 KMAQALPRQRQRDASPG--RGSHGQTPSPGALPLGRQ-TSQQPAG---PPAQQRPPPQGG 466
K A A P ++ + P ++ PSP L + TS P PPA P P+ G
Sbjct: 1568 KEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKG 1627
Query: 467 PPQPGPGPQRQGPP-----LQQRP--PPQGQQHLSGLGPPAGSPLPQR-----------L 508
P P P PP L+ P P + P A LP +
Sbjct: 1628 PATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVA 1687
Query: 509 PSPTSAPQQPA-SQAAPPTQGQGRQSRPVAGGPGAPPAARPP------------------ 549
P+P S P A ++ P T+ S P+ P A ++ P
Sbjct: 1688 PAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSK 1747
Query: 550 ------ASPSPQRQAGPPQATRQTSVSGPA------------------------------ 573
AS SP+ PP++ T ++ A
Sbjct: 1748 TAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPV 1807
Query: 574 ---PPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGP-- 628
PPK P P KP PA P P +G Q + P P
Sbjct: 1808 PTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKS 1867
Query: 629 AGRPKPQLAQK 639
AG P P + K
Sbjct: 1868 AGIPVPTPSAK 1878
Score = 31.2 bits (69), Expect = 3.2
Identities = 23/75 (30%), Positives = 31/75 (41%), Gaps = 5/75 (6%)
Query: 28 PQPPP--PPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGGFFSSLSNAVK 85
P PP PP SPG P G T + +P +P P+ S GG + + K
Sbjct: 1310 PTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGG---PTTPSSK 1366
Query: 86 QTTAAAAATFSEQVG 100
+ AAT S + G
Sbjct: 1367 EGPTPPAATPSHKGG 1381
Score = 30.4 bits (67), Expect = 5.5
Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 6/47 (12%)
Query: 28 PQPPPPPPGAHSPG-----ATPGP-GTATAERSSGVAPAASPAAPSP 68
P+ P PP A P ATP P G T ++ +P PA PSP
Sbjct: 959 PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP 1005
Score = 30.0 bits (66), Expect = 7.2
Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 3/41 (7%)
Query: 28 PQPPP--PPPGAHSPGATPGP-GTATAERSSGVAPAASPAA 65
P PP PP SP ATP P G +T ++ +P SPAA
Sbjct: 1009 PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAA 1049
Score = 29.6 bits (65), Expect = 9.4
Identities = 15/42 (35%), Positives = 21/42 (50%), Gaps = 1/42 (2%)
Query: 28 PQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPG 69
P+ P PP A P GP T + + + PAA+P +P G
Sbjct: 936 PKGAPTPPAATPPSPKGGPATPSPKWAP-TPPAATPPSPKGG 976
>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
Length = 1336
Score = 98.6 bits (244), Expect = 2e-20
Identities = 100/320 (31%), Positives = 121/320 (37%), Gaps = 54/320 (16%)
Query: 399 QDEDKQLIVELVVNKMAQALPRQRQRDASPGRGSHGQTPSPGALPLGR--QTSQQPAGPP 456
Q + QL+ +L + ++AQ Q Q S G G P PG P+ + Q QQP P
Sbjct: 549 QYTNPQLLEQLKIERLAQKQVEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQP--HP 606
Query: 457 AQQRP--PPQGGPPQP-----GPGPQ----RQGPPLQQ-RPPPQGQQHLSG-LGPPAGSP 503
+QQ P Q GPP P PGPQ QGPPL Q PQG G GPP G P
Sbjct: 607 SQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLP 666
Query: 504 LPQRLPSPTSAPQQPASQAAPPTQG----QGRQSRPVAGGPGAPPAAR----PPASPSPQ 555
PQ + P + P QG QG GP PP + P P PQ
Sbjct: 667 RPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQ 726
Query: 556 RQAGPPQATRQTSVSGPAPPKASGAP---------PGGQQRQGPPQK-------PPGPAG 599
GP + GP P+ P PG Q QGP + P G G
Sbjct: 727 GHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQG 786
Query: 600 PTRQASQAGPVPR---TGPPTTQQPRPSGPGPAGRPKPQLAQKPSQ----DVPPPATAAA 652
P GP P+ G P + P PG PQ + P + PPP +
Sbjct: 787 PPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSML 846
Query: 653 G------GPPHPQLKASPAQ 666
G GPP Q + P Q
Sbjct: 847 GPPQELRGPPGSQSQQGPPQ 866
Score = 87.4 bits (215), Expect = 4e-17
Identities = 100/297 (33%), Positives = 114/297 (38%), Gaps = 59/297 (19%)
Query: 416 QALPRQRQRDASPGR----GSHGQTPSPGALPLGRQTSQQPAGPPAQQRPP-PQGG-PPQ 469
Q LPR + G G HG G P G Q S P G Q PP PQG PQ
Sbjct: 663 QGLPRPQDMHGPQGMQRHPGPHGPLGPQG--PPGPQGSSGPQGHMGPQGPPGPQGHIGPQ 720
Query: 470 PGPGPQR----QGPP----LQQRPPPQGQQ---HLSGL----------GPPAGSPLPQRL 508
PGPQ QGPP +Q P P+G Q H G+ GP + PL
Sbjct: 721 GPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLN 780
Query: 509 PSPTSAPQQPASQAAPPTQGQ--GRQSRPVAGG--PGAPPAARPPASPSPQRQAGPPQAT 564
P P P P QG G + + G PG P PQ G
Sbjct: 781 PRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPP 840
Query: 565 RQTSVSGPAPPKASGAPPGGQQRQGPPQ----KPP-----GPAGPTRQASQA-GPVPRTG 614
Q S+ GP P+ PPG Q +QGPPQ PP GP GP Q + A GP P G
Sbjct: 841 PQGSMLGP--PQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQG 898
Query: 615 P-PTTQQPRP-SGPGP----------AGRPK--PQLAQKPSQDVPPPATAAAGGPPH 657
P P QQ P G GP G P P L Q+ +Q PP G P+
Sbjct: 899 PIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPN 955
Score = 73.2 bits (178), Expect = 7e-13
Identities = 84/278 (30%), Positives = 100/278 (35%), Gaps = 30/278 (10%)
Query: 416 QALPRQRQRDASPG----RGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQG----GP 467
Q P PG +G Q P G P G Q P GP Q P PQG P
Sbjct: 750 QGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQG---PPGPRENQGPAPQGMIMGHP 806
Query: 468 PQPGPGPQRQGPPLQQRPPP-QGQQHLSGLG--PPAGSPL--PQRLPSPTSAPQQ---PA 519
PQ GP G L P +G Q + G+ PP GS L PQ L P + Q P
Sbjct: 807 PQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQ 866
Query: 520 SQAAPPTQGQGRQSRPVAGGPGAPPAA-RPPASPSPQRQA-------GPPQATRQTSVSG 571
PP QG G Q P G P P P P +Q GP Q S
Sbjct: 867 GSLGPPPQG-GMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQST 925
Query: 572 PAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGR 631
PP G G Q + PP P GP + S+ P GP + ++ SG GP
Sbjct: 926 GPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSG-GPEHG 984
Query: 632 PKPQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQP 669
P+ + + QD P P P + P P
Sbjct: 985 PE-RGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHP 1021
Score = 36.6 bits (83), Expect = 0.077
Identities = 37/158 (23%), Positives = 56/158 (35%), Gaps = 24/158 (15%)
Query: 380 GRDHIIEVVGSSMPLIGDHQDEDKQLIVELVVNKMAQALPRQRQRDASPGRGSHGQTPSP 439
G +H + P H ++ L MA PR+R PG H + +P
Sbjct: 1191 GHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAP 1250
Query: 440 GALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQH-----LS 494
G P++ R GG + GPGP ++ P + G+ H
Sbjct: 1251 GG--------------PSEDR----GGKGRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDE 1292
Query: 495 GLGPPAGSPLPQR-LPSPTSAPQQPASQAAPPTQGQGR 531
G P GS P R S ++ + + PP +G R
Sbjct: 1293 PFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPPRRGASR 1330
Score = 33.5 bits (75), Expect = 0.65
Identities = 41/195 (21%), Positives = 63/195 (32%), Gaps = 47/195 (24%)
Query: 427 SPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPG-------PQRQGP 479
+P G G P+P P ++P G +PGPG P+ P
Sbjct: 1155 TPRGGRKGLLPTPDEFPRFE----------GGRKPDSWDGNREPGPGHEHFRDTPRPDHP 1204
Query: 480 PLQQRPPPQGQQHLSGLGPPAGSPLPQRLP---SPTSAPQQPASQAAPPTQGQGRQSRPV 536
P P ++ S G S P++ P P ++ + P++ +G + R
Sbjct: 1205 PHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGR-- 1262
Query: 537 AGGPGAP------------------------PAARPPASPSPQRQAGPPQATRQTSVSGP 572
GGPG P PP S +P R + S
Sbjct: 1263 -GGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNS 1321
Query: 573 APPKASGAPPGGQQR 587
PP+ + GG+ R
Sbjct: 1322 GPPRRGASRGGGRGR 1336
Score = 33.1 bits (74), Expect = 0.85
Identities = 25/68 (36%), Positives = 30/68 (44%), Gaps = 3/68 (4%)
Query: 602 RQASQAGPVPRTGPPTT-QQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQL 660
+Q Q P P +G P QP P G GP + PQ Q+P P A GPP PQ
Sbjct: 567 KQVEQIQPPPSSGTPLLGPQPFP-GQGPMSQI-PQGFQQPHPSQQMPMNMAQMGPPGPQG 624
Query: 661 KASPAQAQ 668
+ P Q
Sbjct: 625 QFRPPGPQ 632
Score = 32.0 bits (71), Expect = 1.9
Identities = 48/188 (25%), Positives = 67/188 (35%), Gaps = 20/188 (10%)
Query: 446 RQTSQQPAGPPAQQ-RPPPQGGPPQPGP---GPQRQGPPLQQRPPPQGQQHLSGLGPPAG 501
R+ S + PP + R PP+G PGP GP+ ++ + + G G P G
Sbjct: 1100 REESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRG-RGRGTPRG 1158
Query: 502 SPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPP 561
LP+P P+ + P G + GPG P P P
Sbjct: 1159 G-RKGLLPTPDEFPRFEGGR--KPDSWDGNRE----PGPGHEHFRDTPRPDHPPHDGHSP 1211
Query: 562 QATRQTSVSGPAPPKASGAPPGGQQRQGP----PQKPPGPAGPTRQASQAGPVPRTGPPT 617
A+R+ S S AS P GP ++ P GP+ G R GP
Sbjct: 1212 -ASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKG---RGGPGP 1267
Query: 618 TQQPRPSG 625
Q+ SG
Sbjct: 1268 AQRVPKSG 1275
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 97.4 bits (241), Expect = 4e-20
Identities = 77/247 (31%), Positives = 104/247 (42%), Gaps = 32/247 (12%)
Query: 436 TPSPGALPLG------------RQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQ 483
T P A PLG + +S+QP GP A +PP G P PGP + PP QQ
Sbjct: 358 TTKPPAQPLGPAKPPAQQTGSEKPSSEQP-GPKALAQPPGVGKTPAQQPGPAK--PPTQQ 414
Query: 484 RPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAP 543
P+ GL PA +P P + P P + +Q A P + +Q+ GP P
Sbjct: 415 VGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQT-----GPTKP 469
Query: 544 PAARP-PASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTR 602
P+ P PA P PQ Q GP + Q S P + G+ Q+ GP + P G T+
Sbjct: 470 PSQLPGPAKPPPQ-QPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK 528
Query: 603 QASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKA 662
SQ P + P+ QQP P+ P KP + + PP + P K
Sbjct: 529 PPSQQ---PGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS-------PSAKQ 578
Query: 663 SPAQAQP 669
P+Q P
Sbjct: 579 PPSQGLP 585
Score = 96.3 bits (238), Expect = 8e-20
Identities = 88/272 (32%), Positives = 110/272 (40%), Gaps = 39/272 (14%)
Query: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQ--RPPPQGGPPQPGPGPQR 476
P+ +Q D G PSP P+ + T P PPAQQ Q GP +P P
Sbjct: 281 PQTKQADIVRGESVKPSLPSPSKPPIQQPT---PGKPPAQQPGHEKSQPGPAKPPAQPSG 337
Query: 477 QGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPV 536
PL Q+P G P P P T P QP A PP Q G + +P
Sbjct: 338 LTKPLAQQP---------GTVKPPVQP-----PGTTKPPAQPLGPAKPPAQQTGSE-KPS 382
Query: 537 AGGPGAPPAARPP-ASPSPQRQAGPPQ-ATRQTSVSGP--------APPKASGAPPGGQQ 586
+ PG A+PP +P +Q GP + T+Q P +P KA G Q
Sbjct: 383 SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQ 442
Query: 587 RQGPPQKPPGPAGPTR-QASQAGPV-PRTGPPTTQQPRPSGPGPAGRP--KPQLAQKPSQ 642
+ GP + P AGP + A Q GP P + P +P P PGPA P +P A+ PSQ
Sbjct: 443 QPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502
Query: 643 ---DVPPPATAAAGGPPHPQLKAS--PAQAQP 669
PP P PQ S P QP
Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQP 534
Score = 95.9 bits (237), Expect = 1e-19
Identities = 78/264 (29%), Positives = 100/264 (37%), Gaps = 28/264 (10%)
Query: 426 ASPGRGSHGQTPSPGALPLGRQ--TSQQPAGPPAQQRPPPQG-GPPQPGPGPQRQGPPLQ 482
+ PG PS PL +Q T + P PP +PP Q GP +P P
Sbjct: 324 SQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSS 383
Query: 483 QRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGA 542
++P P+ PP P + P P P Q P Q G QS A GP
Sbjct: 384 EQPGPKALAQ-----PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTK 438
Query: 543 PPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTR 602
P +P P +QAGP + + Q + P + G Q+ GP + PP G +
Sbjct: 439 TPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAK 498
Query: 603 QASQAGPVPRTGPPTTQQPRPSGPGP--AGRPKPQLAQ----KPSQDVPPPATAAA---- 652
SQ P + P QQP P+ P P G KP Q KPS P PA +A
Sbjct: 499 PPSQQ---PGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQST 555
Query: 653 -------GGPPHPQLKASPAQAQP 669
G P SP+ QP
Sbjct: 556 KPVSQTGSGKPLQPPTVSPSAKQP 579
Score = 76.6 bits (187), Expect = 7e-14
Identities = 70/227 (30%), Positives = 95/227 (41%), Gaps = 40/227 (17%)
Query: 415 AQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQP--AGPPAQQRPPPQGGPPQPG- 471
AQ ++ PG + Q P G P +QQP A PP QQ P+ QPG
Sbjct: 373 AQQTGSEKPSSEQPGPKALAQPPGVGKTP-----AQQPGPAKPPTQQVGTPKPLAQQPGL 427
Query: 472 ------PGP-----QRQGP---PLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQ 517
PGP Q+ GP P QQ P + +G P P +LP P P Q
Sbjct: 428 QSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP-----PSQLPGPAKPPPQ 482
Query: 518 PASQAAPPTQGQGRQSRPVAGGPGA--PPAARP-PASPSPQRQAGPPQATRQTSVSGPAP 574
A PP Q G ++P + PG+ PP +P PA PSPQ+ ++Q + P+
Sbjct: 483 QPGPAKPPPQQPG-SAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSA 541
Query: 575 PKASGAPPGGQQR--------QGPPQKPPGPAGPTRQASQAGPVPRT 613
+ S A P QQ G P +PP + +Q G +P+T
Sbjct: 542 QQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQG-LPKT 587
Score = 69.3 bits (168), Expect = 1e-11
Identities = 68/226 (30%), Positives = 90/226 (39%), Gaps = 45/226 (19%)
Query: 455 PPAQQRPPPQGGPPQPGPGPQRQGP---PLQQRPPP-----QGQQHLSGLGPPAGSPL-- 504
PP QQ+PP P P++QGP PLQQ P Q + + P G P+
Sbjct: 209 PPLQQQPPK--------PIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQG 260
Query: 505 PQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQAT 564
P + P A A+ P Q R + P P ++PP
Sbjct: 261 PTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPP--------------- 305
Query: 565 RQTSVSGPAPPKASGAPPGGQQRQGPPQKPPG-PAGPTRQ-ASQAGPV-PRTGPPTTQQP 621
+ P P K PG ++ Q P KPP P+G T+ A Q G V P PP T +P
Sbjct: 306 ----IQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKP 361
Query: 622 RPSGPGPAGRPKPQL-AQKPSQDVPPPATAAAGGPPHPQLKASPAQ 666
GPA P Q ++KPS + P P A P + +PAQ
Sbjct: 362 PAQPLGPAKPPAQQTGSEKPSSEQPGPKALA----QPPGVGKTPAQ 403
Score = 68.9 bits (167), Expect = 1e-11
Identities = 72/274 (26%), Positives = 100/274 (36%), Gaps = 35/274 (12%)
Query: 421 QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQG------GPPQPGPGP 474
Q + +P + PS P G + S P A RP GP G
Sbjct: 786 QAEEKTTPPLKTDSAKPSQSFPPTGEKVS--PFDSKAIPRPASDSKIISHPGPSSESKG- 842
Query: 475 QRQGPPLQQRPPPQGQQHLSGLGP-----PAGSPLPQRLPSPTSAPQQPASQAAPPTQGQ 529
Q+Q P+Q++ P+ Q P P GSP P P PT+ P Q +P Q Q
Sbjct: 843 QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPG-PRPTAGQTVPTPQQSPKPQEQ 901
Query: 530 GRQSRPVAGGPGAPPAARPPASPSPQRQAGPP----------QATRQTSVSG-PAPPKAS 578
R+ G P ++P +PQ QA+ S +G P P S
Sbjct: 902 SRRFSLNLGSITDAPKSQPT---TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQS 958
Query: 579 GAPPGGQQRQGP-PQKPPGPAGPTRQASQAGPVPRTGPPT---TQQPRPSGPGPAGRPKP 634
G PG +Q P P +PP GP + QA P P P T+ P P P
Sbjct: 959 G--PGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAP 1016
Query: 635 QLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQ 668
+ + ++ PPP + PQ P + +
Sbjct: 1017 TVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLE 1050
Score = 58.2 bits (139), Expect = 2e-08
Identities = 60/250 (24%), Positives = 88/250 (35%), Gaps = 28/250 (11%)
Query: 437 PSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQP----GPGPQRQGPPLQQRPPPQGQQH 492
P P+ ++ + P QQ P + P+ P P++ PPL ++P G
Sbjct: 659 PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKP-PPLVKQPTLHGSPS 717
Query: 493 LSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQG----QGRQSRPVAGGPGAPPAARP 548
PP L + P+P P P+ Q P Q + +P + A
Sbjct: 718 AKAKQPPEADSLSK--PAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTK 775
Query: 549 PASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQ---------QRQGPPQK---PPG 596
P PS + Q+ + T + A P S P G + R K PG
Sbjct: 776 PDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPG 835
Query: 597 PAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPP 656
P+ ++ Q PV + P Q + S P P +P P K S P P A P
Sbjct: 836 PSSESKGQKQVDPVQKKEEPKKAQTKMS-PKPDAKPMP----KGSPTPPGPRPTAGQTVP 890
Query: 657 HPQLKASPAQ 666
PQ P +
Sbjct: 891 TPQQSPKPQE 900
Score = 53.9 bits (128), Expect = 5e-07
Identities = 72/279 (25%), Positives = 91/279 (32%), Gaps = 62/279 (22%)
Query: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQ---PAGPPAQQRPPPQGGPPQPGPGPQ 475
P Q+ A P G T P P + S Q PA P AQQ P Q G G
Sbjct: 510 PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS---QTGSGKP 566
Query: 476 RQGP---PLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQ--- 529
Q P P ++PP QG P PL P++ Q
Sbjct: 567 LQPPTVSPSAKQPPSQGL-------PKTICPLCNTTELLLHVPEKANFNTCTECQTTVCS 619
Query: 530 -------------------GRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVS 570
Q + GG AP P+SP P+ + P T S S
Sbjct: 620 LCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPV----PSSPQPKLKTAPVTTTSAVSKS 675
Query: 571 GPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAG 630
P P + S P A P + S+A P P+ PP +QP G A
Sbjct: 676 SPQPQQTS---------------PKKDAAPKQDLSKA-PEPKKPPPLVKQPTLHGSPSAK 719
Query: 631 RPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQP 669
+P A S+ PP + P Q KA A +P
Sbjct: 720 AKQPPEADSLSKPAPPKEPSV----PSEQDKAPVADDKP 754
Score = 52.0 bits (123), Expect = 2e-06
Identities = 58/216 (26%), Positives = 66/216 (30%), Gaps = 50/216 (23%)
Query: 416 QALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQ 475
Q P + SP S P P S QP PP PPP PP P
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPP----- 2423
Query: 476 RQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRP 535
PPP PP SP P LP P + A P
Sbjct: 2424 ---------PPPL---------PPPTSPKPTILPKKKLTVASPVTTATPLFD-------- 2457
Query: 536 VAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGP-PQKP 594
A + + R G P T+ P PPK S P G P P KP
Sbjct: 2458 ---------AVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKP 2508
Query: 595 PGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAG 630
P P +P+ P TTQ+P P P G
Sbjct: 2509 PIAPKPV--------IPQL-PTTTQKPTDIHPKPTG 2535
Score = 41.2 bits (95), Expect = 0.003
Identities = 57/228 (25%), Positives = 77/228 (33%), Gaps = 64/228 (28%)
Query: 496 LGPPAGSPLPQRLPSPT--------SAPQQPASQAAPPTQGQGRQSRPVAGGPGAPP--A 545
L P SP P+ +P S+PQ Q +P +Q A P PP
Sbjct: 650 LAPVPSSPQPKLKTAPVTTTSAVSKSSPQP--QQTSPKKDAAPKQDLSKAPEPKKPPPLV 707
Query: 546 ARPPASPSPQRQAG-PPQATRQTSVSGPAPPKASGAP------PGGQQRQGPPQ------ 592
+P SP +A PP+A S+S PAPPK P P + P+
Sbjct: 708 KQPTLHGSPSAKAKQPPEAD---SLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTT 764
Query: 593 ----------KPPGPAGPTRQASQAGPVP----------RTGPPTTQQ---------PRP 623
KP P+ + ++ P ++ PPT ++ PRP
Sbjct: 765 DLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRP 824
Query: 624 -------SGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASP 664
S PGP+ K Q P Q P A P P K P
Sbjct: 825 ASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMP 872
Score = 34.3 bits (77), Expect = 0.38
Identities = 40/148 (27%), Positives = 52/148 (35%), Gaps = 37/148 (25%)
Query: 510 SPTSAPQQPASQAAPPTQGQGRQSRPVAG---GPGAPPAARPPASPSPQRQAGPPQATRQ 566
S T P+S A P + Q + +G G P + P SPS P+ +
Sbjct: 2336 SETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFR 2395
Query: 567 TS---VSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRP 623
+S +S PP PP PP PP P P P+P PPT+
Sbjct: 2396 SSSLDISAQPPPPPPPPPP-------PPPPPPPPPPP--------PLP---PPTS----- 2432
Query: 624 SGPGPAGRPKPQLAQKPSQDVPPPATAA 651
PKP + K V P T A
Sbjct: 2433 --------PKPTILPKKKLTVASPVTTA 2452
Score = 32.0 bits (71), Expect = 1.9
Identities = 26/87 (29%), Positives = 33/87 (37%), Gaps = 5/87 (5%)
Query: 443 PLGRQTSQQPAGPPAQQRPPPQGGPPQPGPG----PQRQGPPLQQRPPPQGQQHLSGLGP 498
P+ + S P+G RP P P P P P P P P G S +
Sbjct: 2485 PVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTL 2544
Query: 499 PAGSPLPQRLPSPTSAPQQPASQAAPP 525
+ +LPSPTS P P S + P
Sbjct: 2545 NLVTSADYKLPSPTS-PLSPHSNKSSP 2570
Score = 31.6 bits (70), Expect = 2.5
Identities = 25/87 (28%), Positives = 36/87 (41%), Gaps = 11/87 (12%)
Query: 509 PSPTSAPQQPASQAAPPTQGQGRQSRPVAG-GPGAPPAARPPASPSPQRQAGPPQATRQT 567
PS T+ P + + ++ + RQ V G P + PPA+ A P R+
Sbjct: 32 PSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAA------AESPSMHRKQ 85
Query: 568 SVSGPAPPKASGAPPGGQQRQGPPQKP 594
+ PPK SG PP G P +P
Sbjct: 86 ELDSSHPPKQSGRPPD----PGRPAQP 108
Score = 29.6 bits (65), Expect = 9.4
Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 28 PQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAP 66
P PPPPPP P +P P T ++ VA + A P
Sbjct: 2417 PPPPPPPPPPLPPPTSPKP-TILPKKKLTVASPVTTATP 2454
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 97.4 bits (241), Expect = 4e-20
Identities = 77/247 (31%), Positives = 104/247 (42%), Gaps = 32/247 (12%)
Query: 436 TPSPGALPLG------------RQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQ 483
T P A PLG + +S+QP GP A +PP G P PGP + PP QQ
Sbjct: 358 TTKPPAQPLGPAKPPAQQTGSEKPSSEQP-GPKALAQPPGVGKTPAQQPGPAK--PPTQQ 414
Query: 484 RPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAP 543
P+ GL PA +P P + P P + +Q A P + +Q+ GP P
Sbjct: 415 VGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQT-----GPTKP 469
Query: 544 PAARP-PASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTR 602
P+ P PA P PQ Q GP + Q S P + G+ Q+ GP + P G T+
Sbjct: 470 PSQLPGPAKPPPQ-QPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK 528
Query: 603 QASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKA 662
SQ P + P+ QQP P+ P KP + + PP + P K
Sbjct: 529 PPSQQ---PGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS-------PSAKQ 578
Query: 663 SPAQAQP 669
P+Q P
Sbjct: 579 PPSQGLP 585
Score = 96.3 bits (238), Expect = 8e-20
Identities = 88/272 (32%), Positives = 110/272 (40%), Gaps = 39/272 (14%)
Query: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQ--RPPPQGGPPQPGPGPQR 476
P+ +Q D G PSP P+ + T P PPAQQ Q GP +P P
Sbjct: 281 PQTKQADIVRGESVKPSLPSPSKPPIQQPT---PGKPPAQQPGHEKSQPGPAKPPAQPSG 337
Query: 477 QGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPV 536
PL Q+P G P P P T P QP A PP Q G + +P
Sbjct: 338 LTKPLAQQP---------GTVKPPVQP-----PGTTKPPAQPLGPAKPPAQQTGSE-KPS 382
Query: 537 AGGPGAPPAARPP-ASPSPQRQAGPPQ-ATRQTSVSGP--------APPKASGAPPGGQQ 586
+ PG A+PP +P +Q GP + T+Q P +P KA G Q
Sbjct: 383 SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQ 442
Query: 587 RQGPPQKPPGPAGPTR-QASQAGPV-PRTGPPTTQQPRPSGPGPAGRP--KPQLAQKPSQ 642
+ GP + P AGP + A Q GP P + P +P P PGPA P +P A+ PSQ
Sbjct: 443 QPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502
Query: 643 ---DVPPPATAAAGGPPHPQLKAS--PAQAQP 669
PP P PQ S P QP
Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQP 534
Score = 95.9 bits (237), Expect = 1e-19
Identities = 78/264 (29%), Positives = 100/264 (37%), Gaps = 28/264 (10%)
Query: 426 ASPGRGSHGQTPSPGALPLGRQ--TSQQPAGPPAQQRPPPQG-GPPQPGPGPQRQGPPLQ 482
+ PG PS PL +Q T + P PP +PP Q GP +P P
Sbjct: 324 SQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSS 383
Query: 483 QRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGA 542
++P P+ PP P + P P P Q P Q G QS A GP
Sbjct: 384 EQPGPKALAQ-----PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTK 438
Query: 543 PPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTR 602
P +P P +QAGP + + Q + P + G Q+ GP + PP G +
Sbjct: 439 TPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAK 498
Query: 603 QASQAGPVPRTGPPTTQQPRPSGPGP--AGRPKPQLAQ----KPSQDVPPPATAAA---- 652
SQ P + P QQP P+ P P G KP Q KPS P PA +A
Sbjct: 499 PPSQQ---PGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQST 555
Query: 653 -------GGPPHPQLKASPAQAQP 669
G P SP+ QP
Sbjct: 556 KPVSQTGSGKPLQPPTVSPSAKQP 579
Score = 76.6 bits (187), Expect = 7e-14
Identities = 70/227 (30%), Positives = 95/227 (41%), Gaps = 40/227 (17%)
Query: 415 AQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQP--AGPPAQQRPPPQGGPPQPG- 471
AQ ++ PG + Q P G P +QQP A PP QQ P+ QPG
Sbjct: 373 AQQTGSEKPSSEQPGPKALAQPPGVGKTP-----AQQPGPAKPPTQQVGTPKPLAQQPGL 427
Query: 472 ------PGP-----QRQGP---PLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQ 517
PGP Q+ GP P QQ P + +G P P +LP P P Q
Sbjct: 428 QSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP-----PSQLPGPAKPPPQ 482
Query: 518 PASQAAPPTQGQGRQSRPVAGGPGA--PPAARP-PASPSPQRQAGPPQATRQTSVSGPAP 574
A PP Q G ++P + PG+ PP +P PA PSPQ+ ++Q + P+
Sbjct: 483 QPGPAKPPPQQPG-SAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSA 541
Query: 575 PKASGAPPGGQQR--------QGPPQKPPGPAGPTRQASQAGPVPRT 613
+ S A P QQ G P +PP + +Q G +P+T
Sbjct: 542 QQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQG-LPKT 587
Score = 69.3 bits (168), Expect = 1e-11
Identities = 68/226 (30%), Positives = 90/226 (39%), Gaps = 45/226 (19%)
Query: 455 PPAQQRPPPQGGPPQPGPGPQRQGP---PLQQRPPP-----QGQQHLSGLGPPAGSPL-- 504
PP QQ+PP P P++QGP PLQQ P Q + + P G P+
Sbjct: 209 PPLQQQPPK--------PIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQG 260
Query: 505 PQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQAT 564
P + P A A+ P Q R + P P ++PP
Sbjct: 261 PTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPP--------------- 305
Query: 565 RQTSVSGPAPPKASGAPPGGQQRQGPPQKPPG-PAGPTRQ-ASQAGPV-PRTGPPTTQQP 621
+ P P K PG ++ Q P KPP P+G T+ A Q G V P PP T +P
Sbjct: 306 ----IQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKP 361
Query: 622 RPSGPGPAGRPKPQL-AQKPSQDVPPPATAAAGGPPHPQLKASPAQ 666
GPA P Q ++KPS + P P A P + +PAQ
Sbjct: 362 PAQPLGPAKPPAQQTGSEKPSSEQPGPKALA----QPPGVGKTPAQ 403
Score = 68.9 bits (167), Expect = 1e-11
Identities = 72/274 (26%), Positives = 100/274 (36%), Gaps = 35/274 (12%)
Query: 421 QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQG------GPPQPGPGP 474
Q + +P + PS P G + S P A RP GP G
Sbjct: 786 QAEEKTTPPLKTDSAKPSQSFPPTGEKVS--PFDSKAIPRPASDSKIISHPGPSSESKG- 842
Query: 475 QRQGPPLQQRPPPQGQQHLSGLGP-----PAGSPLPQRLPSPTSAPQQPASQAAPPTQGQ 529
Q+Q P+Q++ P+ Q P P GSP P P PT+ P Q +P Q Q
Sbjct: 843 QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPG-PRPTAGQTVPTPQQSPKPQEQ 901
Query: 530 GRQSRPVAGGPGAPPAARPPASPSPQRQAGPP----------QATRQTSVSG-PAPPKAS 578
R+ G P ++P +PQ QA+ S +G P P S
Sbjct: 902 SRRFSLNLGSITDAPKSQPT---TPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQS 958
Query: 579 GAPPGGQQRQGP-PQKPPGPAGPTRQASQAGPVPRTGPPT---TQQPRPSGPGPAGRPKP 634
G PG +Q P P +PP GP + QA P P P T+ P P P
Sbjct: 959 G--PGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAP 1016
Query: 635 QLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQ 668
+ + ++ PPP + PQ P + +
Sbjct: 1017 TVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLE 1050
Score = 58.2 bits (139), Expect = 2e-08
Identities = 60/250 (24%), Positives = 88/250 (35%), Gaps = 28/250 (11%)
Query: 437 PSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQP----GPGPQRQGPPLQQRPPPQGQQH 492
P P+ ++ + P QQ P + P+ P P++ PPL ++P G
Sbjct: 659 PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKP-PPLVKQPTLHGSPS 717
Query: 493 LSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQG----QGRQSRPVAGGPGAPPAARP 548
PP L + P+P P P+ Q P Q + +P + A
Sbjct: 718 AKAKQPPEADSLSK--PAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTK 775
Query: 549 PASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQ---------QRQGPPQK---PPG 596
P PS + Q+ + T + A P S P G + R K PG
Sbjct: 776 PDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPG 835
Query: 597 PAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPP 656
P+ ++ Q PV + P Q + S P P +P P K S P P A P
Sbjct: 836 PSSESKGQKQVDPVQKKEEPKKAQTKMS-PKPDAKPMP----KGSPTPPGPRPTAGQTVP 890
Query: 657 HPQLKASPAQ 666
PQ P +
Sbjct: 891 TPQQSPKPQE 900
Score = 53.9 bits (128), Expect = 5e-07
Identities = 72/279 (25%), Positives = 91/279 (32%), Gaps = 62/279 (22%)
Query: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQ---PAGPPAQQRPPPQGGPPQPGPGPQ 475
P Q+ A P G T P P + S Q PA P AQQ P Q G G
Sbjct: 510 PPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS---QTGSGKP 566
Query: 476 RQGP---PLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQ--- 529
Q P P ++PP QG P PL P++ Q
Sbjct: 567 LQPPTVSPSAKQPPSQGL-------PKTICPLCNTTELLLHVPEKANFNTCTECQTTVCS 619
Query: 530 -------------------GRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVS 570
Q + GG AP P+SP P+ + P T S S
Sbjct: 620 LCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPV----PSSPQPKLKTAPVTTTSAVSKS 675
Query: 571 GPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAG 630
P P + S P A P + S+A P P+ PP +QP G A
Sbjct: 676 SPQPQQTS---------------PKKDAAPKQDLSKA-PEPKKPPPLVKQPTLHGSPSAK 719
Query: 631 RPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQP 669
+P A S+ PP + P Q KA A +P
Sbjct: 720 AKQPPEADSLSKPAPPKEPSV----PSEQDKAPVADDKP 754
Score = 52.0 bits (123), Expect = 2e-06
Identities = 58/216 (26%), Positives = 66/216 (30%), Gaps = 50/216 (23%)
Query: 416 QALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQ 475
Q P + SP S P P S QP PP PPP PP P
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPP----- 2423
Query: 476 RQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRP 535
PPP PP SP P LP P + A P
Sbjct: 2424 ---------PPPL---------PPPTSPKPTILPKKKLTVASPVTTATPLFD-------- 2457
Query: 536 VAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGP-PQKP 594
A + + R G P T+ P PPK S P G P P KP
Sbjct: 2458 ---------AVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKP 2508
Query: 595 PGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAG 630
P P +P+ P TTQ+P P P G
Sbjct: 2509 PIAPKPV--------IPQL-PTTTQKPTDIHPKPTG 2535
Score = 41.2 bits (95), Expect = 0.003
Identities = 57/228 (25%), Positives = 77/228 (33%), Gaps = 64/228 (28%)
Query: 496 LGPPAGSPLPQRLPSPT--------SAPQQPASQAAPPTQGQGRQSRPVAGGPGAPP--A 545
L P SP P+ +P S+PQ Q +P +Q A P PP
Sbjct: 650 LAPVPSSPQPKLKTAPVTTTSAVSKSSPQP--QQTSPKKDAAPKQDLSKAPEPKKPPPLV 707
Query: 546 ARPPASPSPQRQAG-PPQATRQTSVSGPAPPKASGAP------PGGQQRQGPPQ------ 592
+P SP +A PP+A S+S PAPPK P P + P+
Sbjct: 708 KQPTLHGSPSAKAKQPPEAD---SLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTT 764
Query: 593 ----------KPPGPAGPTRQASQAGPVP----------RTGPPTTQQ---------PRP 623
KP P+ + ++ P ++ PPT ++ PRP
Sbjct: 765 DLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRP 824
Query: 624 -------SGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASP 664
S PGP+ K Q P Q P A P P K P
Sbjct: 825 ASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMP 872
Score = 34.3 bits (77), Expect = 0.38
Identities = 40/148 (27%), Positives = 52/148 (35%), Gaps = 37/148 (25%)
Query: 510 SPTSAPQQPASQAAPPTQGQGRQSRPVAG---GPGAPPAARPPASPSPQRQAGPPQATRQ 566
S T P+S A P + Q + +G G P + P SPS P+ +
Sbjct: 2336 SETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFR 2395
Query: 567 TS---VSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRP 623
+S +S PP PP PP PP P P P+P PPT+
Sbjct: 2396 SSSLDISAQPPPPPPPPPP-------PPPPPPPPPPP--------PLP---PPTS----- 2432
Query: 624 SGPGPAGRPKPQLAQKPSQDVPPPATAA 651
PKP + K V P T A
Sbjct: 2433 --------PKPTILPKKKLTVASPVTTA 2452
Score = 32.0 bits (71), Expect = 1.9
Identities = 26/87 (29%), Positives = 33/87 (37%), Gaps = 5/87 (5%)
Query: 443 PLGRQTSQQPAGPPAQQRPPPQGGPPQPGPG----PQRQGPPLQQRPPPQGQQHLSGLGP 498
P+ + S P+G RP P P P P P P P P G S +
Sbjct: 2485 PVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTL 2544
Query: 499 PAGSPLPQRLPSPTSAPQQPASQAAPP 525
+ +LPSPTS P P S + P
Sbjct: 2545 NLVTSADYKLPSPTS-PLSPHSNKSSP 2570
Score = 31.6 bits (70), Expect = 2.5
Identities = 25/87 (28%), Positives = 36/87 (41%), Gaps = 11/87 (12%)
Query: 509 PSPTSAPQQPASQAAPPTQGQGRQSRPVAG-GPGAPPAARPPASPSPQRQAGPPQATRQT 567
PS T+ P + + ++ + RQ V G P + PPA+ A P R+
Sbjct: 32 PSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAA------AESPSMHRKQ 85
Query: 568 SVSGPAPPKASGAPPGGQQRQGPPQKP 594
+ PPK SG PP G P +P
Sbjct: 86 ELDSSHPPKQSGRPPD----PGRPAQP 108
Score = 29.6 bits (65), Expect = 9.4
Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 28 PQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAP 66
P PPPPPP P +P P T ++ VA + A P
Sbjct: 2417 PPPPPPPPPPLPPPTSPKP-TILPKKKLTVASPVTTATP 2454
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 95.5 bits (236), Expect = 1e-19
Identities = 75/215 (34%), Positives = 82/215 (38%), Gaps = 29/215 (13%)
Query: 460 RPPPQG-------GPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPT 512
R PP G GP PGPG PP+ PP Q QQ PP P PQ+ P
Sbjct: 32 RSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQ-----PPPQQPPPQQPPPHQ 86
Query: 513 SAPQ-QPASQAAPPTQGQGRQSRPVAGGPGAPPA--ARPPASPSPQRQAGPPQATRQTSV 569
P QP Q PP Q VA GPG P + PPAS S P S
Sbjct: 87 PPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSG 146
Query: 570 SGPAP---PKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPS-G 625
GP P P + APPG PP PP PT GP P P P G
Sbjct: 147 PGPTPTPPPAVTSAPPGA-----PPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQG 201
Query: 626 PGPAGRPKPQLAQKPSQDVP--PPATAAAGGPPHP 658
PGP G P+ + P P P + GG P P
Sbjct: 202 PGPGG---PKGGKMPGGPKPGGGPGLSTPGGHPKP 233
Score = 93.2 bits (230), Expect = 7e-19
Identities = 82/245 (33%), Positives = 94/245 (38%), Gaps = 47/245 (19%)
Query: 421 QRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPP 480
Q + PG G G P P +Q Q P P Q+PPP PP P P Q+Q PP
Sbjct: 42 QNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPP 101
Query: 481 LQQRPPP----QGQQHLSGLG--PPAGSPLPQRLPSPTSAPQ----------QPASQAAP 524
Q QG G+G PPA S P P + AP PA +AP
Sbjct: 102 PPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAP 161
Query: 525 P-------TQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKA 577
P + P AGGP PPAA P P P++ GP GP K
Sbjct: 162 PGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGP---------GGPKGGKM 212
Query: 578 SGAP-PGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTG----PPTTQQ----PRPSGPGP 628
G P PGG GP PG G + + G PR G PP QQ P P GPG
Sbjct: 213 PGGPKPGG----GPGLSTPG--GHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGPGG 266
Query: 629 AGRPK 633
K
Sbjct: 267 RSEEK 271
Score = 41.2 bits (95), Expect = 0.003
Identities = 22/54 (40%), Positives = 29/54 (53%), Gaps = 6/54 (11%)
Query: 26 QRPQPPPPPPGAHSP----GATPGPGTATAERSSGVAPAASPAAPSPGSSGGGG 75
Q+ QPPPPP + P G P PG +A +S AP A+P P+ G+ G G
Sbjct: 95 QQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATP--PTSGAPPGSG 146
Score = 33.5 bits (75), Expect = 0.65
Identities = 18/53 (33%), Positives = 18/53 (33%)
Query: 23 TDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGG 75
T Q PPPPP PG P G G P PG S GG
Sbjct: 177 TPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGG 229
Score = 31.2 bits (69), Expect = 3.2
Identities = 21/66 (31%), Positives = 24/66 (36%), Gaps = 20/66 (30%)
Query: 28 PQPPPPPPGAH-------------------SPGATPGPGTATAERSSGVAPAASPAAPSP 68
P PPP P H PG PG G+A SS PA P + +P
Sbjct: 84 PHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSA-PPASSSAPPATPPTSGAP 142
Query: 69 GSSGGG 74
SG G
Sbjct: 143 PGSGPG 148
Score = 31.2 bits (69), Expect = 3.2
Identities = 16/43 (37%), Positives = 19/43 (44%), Gaps = 2/43 (4%)
Query: 30 PPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSG 72
P PP PG+ PGP + P A P P+P SSG
Sbjct: 133 PATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPP--PTPPSSG 173
Score = 30.4 bits (67), Expect = 5.5
Identities = 16/47 (34%), Positives = 18/47 (38%), Gaps = 5/47 (10%)
Query: 28 PQPPPPPPGAHSPGATPGP-----GTATAERSSGVAPAASPAAPSPG 69
P P PPP +P P P G T +G P A P PG
Sbjct: 149 PTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPG 195
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 89.4 bits (220), Expect = 1e-17
Identities = 81/241 (33%), Positives = 92/241 (38%), Gaps = 44/241 (18%)
Query: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQG 478
P R A P +G G+ PGA+P G PAGP GGPP P P Q
Sbjct: 189 PGGSSRAAFP-QGGRGRGRFPGAVP-GGDRFPGPAGP---------GGPPPPFPAGQTPP 237
Query: 479 -PPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVA 537
PPL PP GPP P Q LP P + P + PP G+
Sbjct: 238 RPPLGPPGPP---------GPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPF---- 284
Query: 538 GGPGAPPAAR-PPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPG 596
G PP PP P P GPP GP PP+ PP G P +PPG
Sbjct: 285 ---GQPPLGPLPPGPPPPVPGYGPPP--------GPPPPQQGPPPPPGPF----PPRPPG 329
Query: 597 PAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDV-PPPATAAAGGP 655
P GP + A P GPP P PA P P + P+ D PP T G P
Sbjct: 330 PLGPP--LTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRP 387
Query: 656 P 656
P
Sbjct: 388 P 388
Score = 72.0 bits (175), Expect = 2e-12
Identities = 67/200 (33%), Positives = 73/200 (36%), Gaps = 31/200 (15%)
Query: 425 DASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGP--GPQRQGPPLQ 482
D PG G P P P G+ + P GPP PP GPP PG P GPP +
Sbjct: 215 DRFPGPAGPGGPPPP--FPAGQTPPRPPLGPPGPPGPP---GPPPPGQVLPPPLAGPPNR 269
Query: 483 -QRPPPQ--------GQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQS 533
RPPP GQ L L P P+P P P P Q Q PP G
Sbjct: 270 GDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQ---QGPPPPPGPFPPR 326
Query: 534 RPVAGGPGAPPA--ARPPASPSPQRQAGPPQATRQTSVSGPA--PPKASGAPPGGQQRQG 589
P GP PP A PP P P PP A PA PP + P R
Sbjct: 327 PP---GPLGPPLTLAPPPHLPGP-----PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGP 378
Query: 590 PPQKPPGPAGPTRQASQAGP 609
PP P G P + P
Sbjct: 379 PPTDPYGRPPPYDRGDYGPP 398
Score = 67.8 bits (164), Expect = 3e-11
Identities = 51/136 (37%), Positives = 56/136 (41%), Gaps = 21/136 (15%)
Query: 437 PSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQ----GPPLQQRPPPQGQQH 492
P G LP G GPP PP QG PP PGP P R GPPL PPP H
Sbjct: 287 PPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPP----H 342
Query: 493 LSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASP 552
L GPP G+P P +P P PPT G + G P P RPP P
Sbjct: 343 LP--GPPPGAPPPAPHVNPAFFP--------PPT-NSGMPTSDSRGPPPTDPYGRPP--P 389
Query: 553 SPQRQAGPPQATRQTS 568
+ GPP T+
Sbjct: 390 YDRGDYGPPGREMDTA 405
Score = 32.0 bits (71), Expect = 1.9
Identities = 20/62 (32%), Positives = 23/62 (37%), Gaps = 1/62 (1%)
Query: 28 PQPPPPPPGAHSPGATPGP-GTATAERSSGVAPAASPAAPSPGSSGGGGFFSSLSNAVKQ 86
PQ PPPP P PGP G P P AP P FF +N+
Sbjct: 312 PQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMP 371
Query: 87 TT 88
T+
Sbjct: 372 TS 373
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 89.4 bits (220), Expect = 1e-17
Identities = 79/251 (31%), Positives = 92/251 (36%), Gaps = 21/251 (8%)
Query: 432 SHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQ 491
SH +L + +Q PP+ Q PP P P PPLQ P
Sbjct: 497 SHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTP 556
Query: 492 HLSGLGPPAGSPLP-QRLPSP--TSAPQQPASQAAPPTQG-QGRQSRPVAGGPGAP--PA 545
HL PP +P P Q PSP T P+ P+S A PP Q S P+ G P P P
Sbjct: 557 HLE--TPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPL 614
Query: 546 ARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQ-----RQGPPQKPPGPAGP 600
A PP P P QA S P P A+ +P Q P PP P
Sbjct: 615 ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP--- 671
Query: 601 TRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPH--P 658
QA P PP + P P P L PS PP + +A PP P
Sbjct: 672 ---PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 728
Query: 659 QLKASPAQAQP 669
L A P Q P
Sbjct: 729 PLAAPPLQVPP 739
Score = 84.7 bits (208), Expect = 2e-16
Identities = 80/247 (32%), Positives = 92/247 (37%), Gaps = 28/247 (11%)
Query: 426 ASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRP 485
ASP PS L Q P PPA P PP P P PPLQ P
Sbjct: 681 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP-PPLAAPPLQVPP 739
Query: 486 PPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGA-PP 544
PPA P+ PS T P+ P AAPP Q + P A PP
Sbjct: 740 -----------SPPASPPMS---PSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP 785
Query: 545 AARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQA 604
PPA +P QA P + S G AP S + P PPQ PP A P Q
Sbjct: 786 PQAPPALATPPLQALP---SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 842
Query: 605 SQAGPVPRTGPPTTQQP-RPSGPGP---AGRPKPQLAQKPSQDVPPPATAAAGGPPHPQL 660
+ P PT Q P RP PGP P+ LA P PPP+ + + P L
Sbjct: 843 PPSPP----ASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP-PPPSRSPSSTLSGPDL 897
Query: 661 KASPAQA 667
+ A
Sbjct: 898 AGHSSSA 904
Score = 84.3 bits (207), Expect = 3e-16
Identities = 75/246 (30%), Positives = 90/246 (36%), Gaps = 29/246 (11%)
Query: 439 PGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGP 498
P P QT+ P P + PP P P P + P PPP+ ++ P
Sbjct: 539 PSLAPPPLQTASAPLTTPHLETPPC------PAPCPLQAPPSPLTTPPPETPSSIATPPP 592
Query: 499 PA----GSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAA---RPPAS 551
A SP Q LPSP +P A PP Q + P P +PPA+ P A+
Sbjct: 593 QAPPALASPPLQGLPSPPLSP-----LATPPPQAPPXLALPPLQAPPSPPASPPLSPLAT 647
Query: 552 PSPQRQAGPPQATRQTSVSGP------APPKASGAPPGGQQRQGPPQKPPGPAGPTRQAS 605
PSPQ Q S P AP +PP P Q PP A P Q
Sbjct: 648 PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 707
Query: 606 QAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPH--PQLKAS 663
P P PP + P P P L PS PP + +A PP P L A
Sbjct: 708 ---PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAP 764
Query: 664 PAQAQP 669
P Q P
Sbjct: 765 PLQVPP 770
Score = 73.6 bits (179), Expect = 6e-13
Identities = 83/264 (31%), Positives = 94/264 (35%), Gaps = 46/264 (17%)
Query: 437 PSPGALPLGRQTSQQP---AGPPAQQRPPPQGGPP-QPGPGPQRQGPP-----LQQRP-- 485
PSP PL Q P A PP Q P P PP P P Q P L Q P
Sbjct: 607 PSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 666
Query: 486 PPQGQQHLSGLGPPAGSPLP------------------QRLPSPTSAPQQPASQAAPPTQ 527
PP + PPA P+ Q PSP ++P S A PP Q
Sbjct: 667 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS-ATPPPQ 725
Query: 528 GQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGP--APPKASGAPPGGQ 585
+ P P +PPA+ PP SPS A PP + P PP + P
Sbjct: 726 APPPLAAPPLQVPPSPPAS-PPMSPS----ATPPPRVPPLLAAPPLQVPPSPPASLPMSP 780
Query: 586 QRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVP 645
+ PPQ PP A P QA + P G P P A P LA P Q P
Sbjct: 781 LAKPPPQAPPALATPPLQALPSPPASFPG------QAPFSPS-ASLPMSPLATPPPQAPP 833
Query: 646 PPATAAAGGPPHPQLKASPAQAQP 669
A PP P ASP P
Sbjct: 834 VLAAPLLQVPPSP--PASPTLQAP 855
Score = 73.2 bits (178), Expect = 7e-13
Identities = 88/310 (28%), Positives = 104/310 (33%), Gaps = 76/310 (24%)
Query: 436 TPSPGALPLGRQTSQQ-PAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLS 494
TP P LP + P PP+ PP P P P Q PP PP Q L
Sbjct: 325 TPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQ 384
Query: 495 GLGP-----PAGSPLPQRLPSP--------TSAPQQPASQAA------PPTQGQGR---Q 532
+ P SP Q PSP T++ P QA P Q Q
Sbjct: 385 TIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSP 444
Query: 533 SRPVAGGPGAPPAARP---PASPSPQRQAGP------------------------PQATR 565
SRP + P +PP P PASP Q P PQA
Sbjct: 445 SRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPL 504
Query: 566 QTSVSGPAPPKASGAPPGGQQRQG-----PPQKPPGPAGPTRQASQA------------- 607
+ + P ++S APP Q P + P A P Q + A
Sbjct: 505 SSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCP 564
Query: 608 GPVPRTGPPT-TQQPRPSGPGPAGRPKPQ----LAQKPSQDVP-PPATAAAGGPPH--PQ 659
P P PP+ P P P P PQ LA P Q +P PP + A PP P
Sbjct: 565 APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPX 624
Query: 660 LKASPAQAQP 669
L P QA P
Sbjct: 625 LALPPLQAPP 634
Score = 71.2 bits (173), Expect = 3e-12
Identities = 75/274 (27%), Positives = 101/274 (36%), Gaps = 44/274 (16%)
Query: 408 ELVVNKMAQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGP 467
E V A P++ A R + G TP + + R+ S+ RP P P
Sbjct: 140 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR-SRAAGTEVGLPRPAPSARP 198
Query: 468 PQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQ 527
P GP++ + + SP +R PS Q+PAS++ +
Sbjct: 199 RPPTEGPRKSVSSASEHSTTEP------------SPAARRRPSAGGGLQRPASRSL--SS 244
Query: 528 GQGRQSRPVAGGPGAPPAARPPASPSPQRQAG-----PPQATRQTSVSGPAPPKASGAPP 582
S P GP A R PA PS + G PPQ T PP+ AP
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT---------PPRKDAAPA 295
Query: 583 GGQQRQGPPQKPPGPAGPTRQA-----SQAGPVPRTGPPT--TQQPRPSGPGPAGRPKPQ 635
G P P P+G + + A P+P T PP+ P P P P+ P
Sbjct: 296 LGPLSSSP-LATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAP-PSPSAPPS 353
Query: 636 LAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQP 669
L PS PPAT + P P + P QA P
Sbjct: 354 LQTLPS----PPATPPSQAP--PSMTTPPMQAPP 381
Score = 66.6 bits (161), Expect = 7e-11
Identities = 83/264 (31%), Positives = 95/264 (35%), Gaps = 38/264 (14%)
Query: 416 QALPRQRQRDASPGRGSHGQTP-SPGA-LPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPG 473
QALP SP GQ P SP A LP+ + P PP P Q PP P
Sbjct: 798 QALP-------SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV-PPSPPAS 849
Query: 474 PQRQGPPLQQRPPPQGQQHLSGLGP-------PAGSPLPQRLPSPT-SAPQ---QPASQA 522
P Q P +RPP G S GP P P P R PS T S P +S
Sbjct: 850 PTLQAP---RRPPTPGPD-TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 905
Query: 523 APPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPP 582
+ P + +G S P G +PP P + A P A + GPAPP A P
Sbjct: 906 STPEELRGYDSGPEGGAAASPP-------PDAELAACHPAAWSR----GPAPPLAFRGAP 954
Query: 583 GGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQ 642
G P P G GP T P P PS PG +G K
Sbjct: 955 GAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPS-PGTSG-GKAAAGAGAGA 1012
Query: 643 DVPPPATAAAGGPPHPQLKASPAQ 666
P A G P L+AS Q
Sbjct: 1013 SSRSPKQARLGELPLGALQASVVQ 1036
Score = 58.9 bits (141), Expect = 1e-08
Identities = 67/258 (25%), Positives = 86/258 (33%), Gaps = 31/258 (12%)
Query: 443 PLGRQTSQQPAGPPAQQRPPPQGGPPQP---GPGPQRQGPPLQQRPPPQGQQHLSGLGPP 499
P R PP RPPP P G PL +R G + P
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 500 AGSPLPQRLPSPTSAPQQPAS---QAAPPTQGQ--------GRQSRPVAGGP-------- 540
AG S A + PAS + APP + GR S GP
Sbjct: 77 AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 136
Query: 541 -GAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPG-------GQQRQGPPQ 592
AR A+ +P+R A A R TS P P + A G R P
Sbjct: 137 SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSA 196
Query: 593 KPPGPA-GPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAA 651
+P P GP + S A T P + RPS G RP + + + PA +
Sbjct: 197 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG 256
Query: 652 AGGPPHPQLKASPAQAQP 669
P+ A P+Q +P
Sbjct: 257 PSARGTPRAPAHPSQPKP 274
Score = 56.2 bits (134), Expect = 9e-08
Identities = 80/288 (27%), Positives = 98/288 (34%), Gaps = 57/288 (19%)
Query: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPA--GPPAQQRPPPQGGPPQPGP-GPQ 475
P R+R P G Q P+ +L PA GP A+ P P QP P G Q
Sbjct: 222 PAARRR---PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 278
Query: 476 RQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSA-PQQPASQAAPPTQGQGRQSR 534
PP Q PP+ + LGP + SPL PS T A P P AA P S
Sbjct: 279 ALRPP--QVTPPR-KDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSP 335
Query: 535 PVA--------------------GGPGAPPAARPPASPSPQRQAGP----------PQAT 564
P+A P PP+ PP+ +P QA P P +
Sbjct: 336 PLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSL 395
Query: 565 RQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPS 624
S+ P P A + Q PT QA+ + P TQ S
Sbjct: 396 TSPSLQAPPSPLALSS----------LQATTSLGSPTLQATHS--FLTMSPRQTQASLTS 443
Query: 625 GPGPAGRP--KPQLAQKPSQDVPPP---ATAAAGGPPHPQLKASPAQA 667
PA P P L S PP + + A P L P QA
Sbjct: 444 PSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQA 491
Score = 43.1 bits (100), Expect = 8e-04
Identities = 32/92 (34%), Positives = 44/92 (47%), Gaps = 10/92 (10%)
Query: 24 DLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSG----GGGFFSS 79
+ + P+ P PGA PG P PGT+ + ++G AS +P G G S
Sbjct: 977 ETEGPESATPAPGALDPG--PSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASV 1034
Query: 80 LSNAVKQTTAAAAATFSEQVGGGSGGAGRGGA 111
+ + + +T AAA E GGSGG G GGA
Sbjct: 1035 VQHLLSRTLLLAAA---EGAAGGSGG-GPGGA 1062
Score = 39.3 bits (90), Expect = 0.012
Identities = 31/115 (26%), Positives = 44/115 (38%), Gaps = 14/115 (12%)
Query: 531 RQSRPVAGGPGAPPAARPPASPSPQRQAGP-------PQATRQTSVSGPAPPKASGAPPG 583
++ + AG PAAR P +P+ P P A R +G K G
Sbjct: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63
Query: 584 GQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQ------PRPSGPGPAGRP 632
G P+ P AGPTR A + P + PP + + + + PGP P
Sbjct: 64 GIGGATIPESAP-RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSP 117
Score = 38.1 bits (87), Expect = 0.026
Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 3/89 (3%)
Query: 25 LQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGGFFSSLSNAV 84
LQ P PP P +P P PG T+ + A +P P P S S+LS
Sbjct: 840 LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS---STLSGPD 896
Query: 85 KQTTAAAAATFSEQVGGGSGGAGRGGAAS 113
+++A + E++ G G G AAS
Sbjct: 897 LAGHSSSATSTPEELRGYDSGPEGGAAAS 925
Score = 33.5 bits (75), Expect = 0.65
Identities = 30/101 (29%), Positives = 34/101 (33%), Gaps = 7/101 (6%)
Query: 20 GYMTDLQRPQPPPPPPGAHSPGATP-----GPGTATAERSSGVAPAASPAAPSPGSSGGG 74
GY + + PPP A P GP A R + AP P A PGS+ G
Sbjct: 913 GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL 972
Query: 75 GFFSSLSNAVKQTTAAAAATFSEQVG--GGSGGAGRGGAAS 113
T A A G GG AG G AS
Sbjct: 973 CTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGAS 1013
Score = 30.8 bits (68), Expect = 4.2
Identities = 21/77 (27%), Positives = 29/77 (37%), Gaps = 5/77 (6%)
Query: 31 PPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGGFFSSLSNAVKQTTAA 90
P P P A T GP + + S SPAA S+GGG L ++ ++
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG-----LQRPASRSLSS 244
Query: 91 AAATFSEQVGGGSGGAG 107
+A S G G
Sbjct: 245 SATPLSSPARSGPSARG 261
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 89.4 bits (220), Expect = 1e-17
Identities = 81/274 (29%), Positives = 97/274 (35%), Gaps = 35/274 (12%)
Query: 426 ASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRP 485
A+ G+H + SP + P A PPP G G GPQR GPP +RP
Sbjct: 54 AAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRP 113
Query: 486 --PPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAP--PTQGQGRQSRPVAGGPG 541
P + L PP P P +A + AP P + G + GPG
Sbjct: 114 LVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPG 173
Query: 542 APPAARPPASPSPQRQAGPPQATRQTSVS------------------GPAP--PKASGAP 581
P P P P + AGP A + GPA P A
Sbjct: 174 PGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAA 233
Query: 582 PGGQQRQGPP----QKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLA 637
PG Q PP PP PA P+ A+ A P PP P P P RP A
Sbjct: 234 PG-TVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPP----PPPPAPATLARPPGHPA 288
Query: 638 QKPSQD--VPPPATAAAGGPPHPQLKASPAQAQP 669
P+ VPPPA A GG +PA P
Sbjct: 289 GPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGP 322
Score = 84.0 bits (206), Expect = 4e-16
Identities = 85/275 (30%), Positives = 95/275 (34%), Gaps = 48/275 (17%)
Query: 428 PGRGSHGQ-TPSPGALPLGRQTSQQPAGPP---------AQQRPPPQGGP-PQPGPGPQR 476
P GS G P P A + PAGP A+ P P GP P PGPGP +
Sbjct: 129 PPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGK 188
Query: 477 QGPP------------LQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQP-ASQAA 523
P L L GP A PLP+ T P AA
Sbjct: 189 PAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAA 248
Query: 524 PPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPG 583
PP S P A P AP AA PP P+P A PP + PA P + A G
Sbjct: 249 PPAPAA--PSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNG 306
Query: 584 GQQRQGPPQKPP--GPAGPTRQ----ASQAGPVP-----------RTGPPTTQQPRPSGP 626
G P P GPAG + Q A+ A P P + PP Q SGP
Sbjct: 307 GSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGP 366
Query: 627 GPAGR-----PKPQLAQKPSQDVPPPATAAAGGPP 656
P Q A VPPPA G P
Sbjct: 367 ASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLP 401
Score = 82.4 bits (202), Expect = 1e-15
Identities = 77/275 (28%), Positives = 96/275 (34%), Gaps = 27/275 (9%)
Query: 408 ELVVNKMAQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGP 467
E VV+ + +L Q A+ +TP A G + +G PA G
Sbjct: 19 EKVVSDLVGSLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPA--------GA 70
Query: 468 PQPGPGPQRQGPP-LQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPT 526
GP +G P PPP G+ G GP P R P + P PA++ PP
Sbjct: 71 AGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPP 130
Query: 527 QGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQ-ATRQTSVSGPAPPKASGAPPGGQ 585
+G PV A A PA P + AGP A R GP P G PG
Sbjct: 131 EGSAGSCAPVPAA-AAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKP 189
Query: 586 QRQGPPQKPPGPAGPTRQASQAG--------------PVPRTGPPTTQQPRPSGPGPAGR 631
G Q G A A P+P+ P T P G A
Sbjct: 190 AGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAP 249
Query: 632 PKPQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQ 666
P P P+ P PA AA PP P A+ A+
Sbjct: 250 PAPAAPSPPA--APAPAAPAAAPPPPPPAPATLAR 282
Score = 52.8 bits (125), Expect = 1e-06
Identities = 58/229 (25%), Positives = 75/229 (32%), Gaps = 34/229 (14%)
Query: 437 PSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPG-------PGPQRQGPPLQQRPPPQG 489
P P A G PA PA P G P PG PG + + P + P
Sbjct: 298 PPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPA 357
Query: 490 QQHLSGLGPPA-------GSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGA 542
Q L+ GP + G + LPSP + P PP G P GA
Sbjct: 358 AQTLAASGPASTAASMVIGPTMQGALPSPAAVP--------PPAPG-----TPTGLPKGA 404
Query: 543 PPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPP-------QKPP 595
A S +P +AT +V P P+ P Q Q PP +
Sbjct: 405 AGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQ 464
Query: 596 GPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDV 644
P + +Q P TT PRP+ P A + Q P +
Sbjct: 465 LLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPI 513
Score = 38.1 bits (87), Expect = 0.026
Identities = 27/85 (31%), Positives = 35/85 (41%), Gaps = 28/85 (32%)
Query: 30 PPPPPPG----AHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGGFFSSLSNAVK 85
PPPPPP A PG GP P A+PA P P ++ GG
Sbjct: 270 PPPPPPAPATLARPPGHPAGP------------PTAAPAVPPPAAAQNGG---------- 307
Query: 86 QTTAAAAATFSEQVGGGSGGAGRGG 110
+A AA + GG +G +G+ G
Sbjct: 308 --SAGAAPAPAPAAGGPAGVSGQPG 330
Score = 33.1 bits (74), Expect = 0.85
Identities = 21/67 (31%), Positives = 28/67 (41%), Gaps = 8/67 (11%)
Query: 17 LPNGYMTDLQRPQPPP--------PPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68
+P G + +PPP P P A + A P P A + +G A A+ A P P
Sbjct: 115 VPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGP 174
Query: 69 GSSGGGG 75
G G G
Sbjct: 175 GPGPGPG 181
Score = 33.1 bits (74), Expect = 0.85
Identities = 20/59 (33%), Positives = 25/59 (42%), Gaps = 7/59 (11%)
Query: 18 PNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVA-------PAASPAAPSPG 69
P G+ P PPP A G + G A A + G A P A+ AAP+PG
Sbjct: 283 PPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPG 341
Score = 33.1 bits (74), Expect = 0.85
Identities = 30/89 (33%), Positives = 36/89 (40%), Gaps = 14/89 (15%)
Query: 482 QQRPPPQGQQHLSGLGPPAGSPLPQR-----LPSPTSAPQQPASQAAPPTQ-GQGRQSRP 535
QQ+PPP Q + L S QR + TSA Q P PTQ G G+Q +P
Sbjct: 679 QQQPPPPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVGVGKQGQP 738
Query: 536 VAGGPGAPPAARPPASPSPQRQAGPPQAT 564
P + P P P PPQ T
Sbjct: 739 ------TPLVIQQP--PKPGALIRPPQVT 759
Score = 30.8 bits (68), Expect = 4.2
Identities = 28/93 (30%), Positives = 34/93 (36%), Gaps = 5/93 (5%)
Query: 19 NGYMTDLQRPQPPPPPPGAHSP---GATPGPGTATAERSSGVAPAASPAAPSPGSSGGGG 75
NG L P+P P +P GA P A + APAA AAP P
Sbjct: 220 NGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPAT 279
Query: 76 FFSSLSNAVKQTTAAAAA--TFSEQVGGGSGGA 106
+ TAA A + Q GG +G A
Sbjct: 280 LARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAA 312
Score = 30.4 bits (67), Expect = 5.5
Identities = 27/90 (30%), Positives = 33/90 (36%), Gaps = 10/90 (11%)
Query: 28 PQPPPPPPGAHSPGATPGPGTATAER---SSGVAPAASPAAPSPGSSGGGGFFSSLSNAV 84
P+PPP G PG + R +G AP A+ P P S G S A
Sbjct: 87 PEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAG-------SCAP 139
Query: 85 KQTTAAAAATFSEQVGGGSGGAGRGGAASR 114
AA AA G + AG A+R
Sbjct: 140 VPAAAAVAAGPEPAPAGPAKPAGPAALAAR 169
Score = 30.4 bits (67), Expect = 5.5
Identities = 20/61 (32%), Positives = 25/61 (40%), Gaps = 8/61 (13%)
Query: 28 PQPPPPPPGAHSPGATPGPGTATAERSSG--------VAPAASPAAPSPGSSGGGGFFSS 79
P P P G PGPG A A + G V AA PAA + +SG +S
Sbjct: 313 PAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAAS 372
Query: 80 L 80
+
Sbjct: 373 M 373
>gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2
preproprotein [Homo sapiens]
Length = 198
Score = 89.4 bits (220), Expect = 1e-17
Identities = 69/185 (37%), Positives = 78/185 (42%), Gaps = 25/185 (13%)
Query: 452 PAGPPAQQRPPPQGGPPQPGP--GPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLP 509
P GP Q PQG PP PG GP QG Q PPP G+ GPP P +
Sbjct: 36 PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ----GPP---PQGDKSR 88
Query: 510 SPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSV 569
SP S P +P PP QG Q P GG +P P P + GPP S
Sbjct: 89 SPRSPPGKPQG---PPPQGGKPQGPPPQGGN------KPQGPPPPGKPQGPPAQGGSKSQ 139
Query: 570 SGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRT-GPPTTQQPRPSGPGP 628
S +PP PP QQ PQ PP PAG Q QA P + GPP P G P
Sbjct: 140 SARSPPGKPQGPP--QQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRP----PQGGRP 193
Query: 629 AGRPK 633
+ P+
Sbjct: 194 SRPPQ 198
Score = 86.7 bits (213), Expect = 6e-17
Identities = 70/180 (38%), Positives = 76/180 (42%), Gaps = 22/180 (12%)
Query: 453 AGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPA--GSPLPQ--RL 508
AG P Q P PQGG GP P P Q PPPQG G PP P PQ +
Sbjct: 33 AGNP--QGPSPQGGNKPQGPPPP---PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKS 87
Query: 509 PSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTS 568
SP S P +P PP QG Q P GG +P P P + GPP S
Sbjct: 88 RSPRSPPGKP---QGPPPQGGKPQGPPPQGG------NKPQGPPPPGKPQGPPAQGGSKS 138
Query: 569 VSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPV--PRTGPPTTQQPRPSGP 626
S +PP PP QQ PQ PP PAG Q QA P P+ P Q RPS P
Sbjct: 139 QSARSPPGKPQGPP--QQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 196
Score = 84.7 bits (208), Expect = 2e-16
Identities = 58/169 (34%), Positives = 66/169 (39%), Gaps = 17/169 (10%)
Query: 497 GP-PAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPA----ARPPAS 551
GP P G PQ P P PQ P PP G Q P G P PP +R P S
Sbjct: 38 GPSPQGGNKPQGPPPPPGKPQGP-----PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS 92
Query: 552 PSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVP 611
P + Q PPQ + PP G P G G PQ PP G Q++++ P
Sbjct: 93 PPGKPQGPPPQGGKPQG-----PPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGK 147
Query: 612 RTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVP--PPATAAAGGPPHP 658
GPP + P GP P PQ Q P P PP G P P
Sbjct: 148 PQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 196
Score = 74.7 bits (182), Expect = 3e-13
Identities = 72/214 (33%), Positives = 87/214 (40%), Gaps = 47/214 (21%)
Query: 405 LIVELVVNKMAQALPRQRQRDASPGR-GSHGQTPSPGALPLGRQTSQQPAGPPAQ-QRPP 462
L V L+ AQ L ++ SP + Q PSP G Q P PP + Q PP
Sbjct: 6 LSVALLALSSAQNLNEDVSQEESPSLIAGNPQGPSPQ----GGNKPQGPPPPPGKPQGPP 61
Query: 463 PQGGPPQPGPGP--QRQGPPLQ--------------QRPPPQGQQHLSGLGPPAGSPLPQ 506
PQGG GP P + QGPP Q Q PPPQG + PP G PQ
Sbjct: 62 PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGP--PPQGGNKPQ 119
Query: 507 RLPSPTSAPQQPASQA--------APPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQA 558
P P PQ P +Q +PP + QG + P PP PPA +PQ+
Sbjct: 120 G-PPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQE-GNNPQGPP---PPAGGNPQQPQ 174
Query: 559 GPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQ 592
PP Q PP+ PP G + PPQ
Sbjct: 175 APPAGQPQ------GPPR----PPQGGRPSRPPQ 198
Score = 62.4 bits (150), Expect = 1e-09
Identities = 51/136 (37%), Positives = 59/136 (43%), Gaps = 24/136 (17%)
Query: 536 VAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPP-GGQQRQGPPQKP 594
+AG P P P PQ GPP P P K G PP GG + QGPP P
Sbjct: 32 IAGNPQGP---SPQGGNKPQ---GPP----------PPPGKPQGPPPQGGNKPQGPP--P 73
Query: 595 PG-PAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAG 653
PG P GP Q ++ PR+ P Q P P G P G P PQ KP PPP G
Sbjct: 74 PGKPQGPPPQGDKSRS-PRSPPGKPQGPPPQGGKPQG-PPPQGGNKPQG--PPPPGKPQG 129
Query: 654 GPPHPQLKASPAQAQP 669
P K+ A++ P
Sbjct: 130 PPAQGGSKSQSARSPP 145
Score = 53.5 bits (127), Expect = 6e-07
Identities = 43/126 (34%), Positives = 55/126 (43%), Gaps = 18/126 (14%)
Query: 549 PASPSPQ---RQAGPPQATRQTSVSGPAPP---KASGAPPGGQQRQGPPQKPPGPAGPTR 602
P PSPQ + GPP + GP P K G PP G+ QGPP P G
Sbjct: 36 PQGPSPQGGNKPQGPPPPPGKPQ--GPPPQGGNKPQGPPPPGK-PQGPP-----PQGDKS 87
Query: 603 QASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKA 662
++ ++ P GPP Q +P GP P G KPQ P + PP A GG ++
Sbjct: 88 RSPRSPPGKPQGPP-PQGGKPQGPPPQGGNKPQGPPPPGKPQGPP---AQGGSKSQSARS 143
Query: 663 SPAQAQ 668
P + Q
Sbjct: 144 PPGKPQ 149
Score = 32.3 bits (72), Expect = 1.5
Identities = 24/79 (30%), Positives = 29/79 (36%), Gaps = 10/79 (12%)
Query: 586 QRQGPPQKPPGPAGPTRQASQA--GPVPRTGPPTTQQP------RPSGPGPAGRPKPQLA 637
Q + P P GP+ Q GP P G P Q P +P GP P G+P+
Sbjct: 25 QEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKP--QGPPPQGGNKPQGPPPPGKPQGPPP 82
Query: 638 QKPSQDVPPPATAAAGGPP 656
Q P GPP
Sbjct: 83 QGDKSRSPRSPPGKPQGPP 101
Score = 31.6 bits (70), Expect = 2.5
Identities = 15/42 (35%), Positives = 17/42 (40%), Gaps = 5/42 (11%)
Query: 27 RPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68
+PQ PPPP PG GP + G P P P P
Sbjct: 46 KPQGPPPP-----PGKPQGPPPQGGNKPQGPPPPGKPQGPPP 82
Score = 31.2 bits (69), Expect = 3.2
Identities = 19/58 (32%), Positives = 22/58 (37%), Gaps = 5/58 (8%)
Query: 16 NLPNGYMTDLQRPQPPPP-----PPGAHSPGATPGPGTATAERSSGVAPAASPAAPSP 68
N P G +PQ PPP P G PG GP + S +P P P P
Sbjct: 45 NKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP 102
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 89.0 bits (219), Expect = 1e-17
Identities = 80/287 (27%), Positives = 98/287 (34%), Gaps = 60/287 (20%)
Query: 430 RGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQR----P 485
+G+ G + PG G Q PAGPP ++ P GP P QG Q+ P
Sbjct: 929 KGARGDSGPPGRA--GEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLP 986
Query: 486 PPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAP----PTQGQGRQSRPVAGGP- 540
+G++ GL P+G P Q P + P P P GR+ P A GP
Sbjct: 987 GQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPP 1046
Query: 541 ------------------GAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPP 582
GAP A PP SP P G + GP P
Sbjct: 1047 GRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGAR 1106
Query: 583 GGQQRQGPP-----------------------QKPPGPAGPTRQASQAGPVPRTGPPTTQ 619
G Q QGP Q PGP GP+ +GP +GP
Sbjct: 1107 GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPP 1166
Query: 620 QP-RPSG-------PGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHP 658
P PSG PGP G P P+ + PP GPP P
Sbjct: 1167 GPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGP 1213
Score = 86.3 bits (212), Expect = 8e-17
Identities = 79/254 (31%), Positives = 93/254 (36%), Gaps = 38/254 (14%)
Query: 429 GRGSHGQTPSPGALPLGRQTSQQPAGPP-------AQQRPPPQGGPPQPGPGPQRQGPPL 481
GRG G PG P G + GPP A+ P +G PGP P
Sbjct: 784 GRGLTGPIGPPG--PAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGA 841
Query: 482 QQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPG 541
+P +G+Q +G AG+P PQ PS PQ P P +G Q P G G
Sbjct: 842 DGQPGAKGEQGEAGQKGDAGAPGPQG-PSGAPGPQGPTG-VTGPKGARGAQGPP--GATG 897
Query: 542 APPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPP--QKPPGPAG 599
P AA P GPP + GP + PPG R G P Q P GP G
Sbjct: 898 FPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPG---RAGEPGLQGPAGPPG 954
Query: 600 PTRQASQAGPVPRTGPPTTQ-----------------QPRPSGPGPAGRPKPQLAQKPSQ 642
+ GP GPP Q + P PGP+G P Q A S
Sbjct: 955 EKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASG 1014
Query: 643 DVPPPATAAAGGPP 656
D PP GPP
Sbjct: 1015 DRGPPGPV---GPP 1025
Score = 77.4 bits (189), Expect = 4e-14
Identities = 65/217 (29%), Positives = 81/217 (37%), Gaps = 18/217 (8%)
Query: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPP-QPGPGPQRQ 477
P + SPG P LP G + PAG + Q GP PGP
Sbjct: 305 PGVKGESGSPGENGSPGPMGPRGLP-GERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAG 363
Query: 478 GPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVA 537
GP P +G+ +G P G+ P+ P +P + P T G
Sbjct: 364 GPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDG----IPGAK 419
Query: 538 GGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPG--GQQRQGPPQKPP 595
G GAP A P P P+ GP AT GP PK PG G + + P+ P
Sbjct: 420 GSAGAPGIAGAPGFPGPRGPPGPQGAT------GPLGPKGQTGEPGIAGFKGEQGPKGEP 473
Query: 596 GPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRP 632
GPAGP AG + G + P G GP G P
Sbjct: 474 GPAGPQGAPGPAGEEGKRG----ARGEPGGVGPIGPP 506
Score = 75.5 bits (184), Expect = 1e-13
Identities = 86/295 (29%), Positives = 101/295 (34%), Gaps = 59/295 (20%)
Query: 412 NKMAQALPRQRQRDASPGR----GSHGQTPSPGALPLGRQTSQQPAGP----------PA 457
+K + P R RD PG G G PG LG + Q AG
Sbjct: 139 DKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV 198
Query: 458 QQRPP-PQG--GPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSA 514
Q P P G GPP P P QG Q P G+ +SG P G P P P
Sbjct: 199 MQGPMGPMGPRGPPGPAGAPGPQG--FQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGE 256
Query: 515 PQQP--ASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSG- 571
+P A + PP R G PG P + +AG P ++ G
Sbjct: 257 AGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGE 316
Query: 572 ---PAPPKASGAPPGGQQRQGP--------------PQKPPGPAGPTR---------QAS 605
P P G P G + R GP P PPGP GP
Sbjct: 317 NGSPGPMGPRGLP-GERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKG 375
Query: 606 QAGPVPRTGPPTTQQPR-----PSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGP 655
+AGP GP Q PR P PGPAG + P D P A +AG P
Sbjct: 376 EAGPTGARGPEGAQGPRGEPGTPGSPGPAG-----ASGNPGTDGIPGAKGSAGAP 425
Score = 75.1 bits (183), Expect = 2e-13
Identities = 71/239 (29%), Positives = 86/239 (35%), Gaps = 41/239 (17%)
Query: 428 PGR-GSHGQTPSPG-ALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRP 485
PG+ G G PG A P G + Q GP Q P GPP G P QG P +
Sbjct: 632 PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA 691
Query: 486 P----PQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPG 541
P P+G++ G GSP Q L P P P G A GP
Sbjct: 692 PGLVGPRGERGFPG---ERGSPGAQGLQGPRGLPGTP-----------GTDGPKGASGPA 737
Query: 542 APPAARPP----ASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGP 597
PP A+ P P + AG G P+ + GG+ G P PPGP
Sbjct: 738 GPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTG-PIGPPGP 796
Query: 598 AGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPP 656
AG + + GP PGPAG + A + PP A GPP
Sbjct: 797 AGANGEKGEVGP----------------PGPAGSAGARGAPGERGETGPPGPAGFAGPP 839
Score = 74.7 bits (182), Expect = 3e-13
Identities = 75/246 (30%), Positives = 85/246 (34%), Gaps = 27/246 (10%)
Query: 430 RGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQG 489
RG G+ SPGA G Q + G P P GP P P QGPP Q P G
Sbjct: 701 RGFPGERGSPGAQ--GLQGPRGLPGTPGTDGPKGASGPAGP---PGAQGPPGLQGMP--G 753
Query: 490 QQHLSGLGPPAGSPLPQRLPSPTSAPQQ------------PASQAAPPTQGQGRQSRPV- 536
++ +G+ P G P AP + P A +G+ P
Sbjct: 754 ERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAG 813
Query: 537 -AGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPP 595
AG GAP P P AGPP A Q G G QG P P
Sbjct: 814 SAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQG-PSGAP 872
Query: 596 GPAGPTRQASQAGPVPRTGPP-TTQQPRPSG----PGPAGRPKPQLAQKPSQDVPPPATA 650
GP GPT G GPP T P +G PG G P P PS P
Sbjct: 873 GPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGAR 932
Query: 651 AAGGPP 656
GPP
Sbjct: 933 GDSGPP 938
Score = 73.6 bits (179), Expect = 6e-13
Identities = 73/252 (28%), Positives = 89/252 (35%), Gaps = 21/252 (8%)
Query: 430 RGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQG 489
RG G+ +PG P GR G P PP GPP G G G
Sbjct: 137 RGDKGEKGAPG--PRGRDGEPGTPGNPGPPGPPGPPGPP--GLGGNFAAQMAGGFDEKAG 192
Query: 490 QQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPP 549
L + P G P+ P P AP Q P G+ S P+ GP PP PP
Sbjct: 193 GAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPM--GPRGPPG--PP 248
Query: 550 ASPSPQRQAGPPQATRQTSVSGPAPPKA-SGAP--PGGQQRQGPP--QKPPGPAGPTRQA 604
P +AG P + GP + G P PG + +G P G AG
Sbjct: 249 GKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVK 308
Query: 605 SQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQ-------KPSQDVPPPATAAAGGPPH 657
++G G P PR PG GR P A +P PP AGGP
Sbjct: 309 GESGSPGENGSPGPMGPRGL-PGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGF 367
Query: 658 PQLKASPAQAQP 669
P + +A P
Sbjct: 368 PGAPGAKGEAGP 379
Score = 72.0 bits (175), Expect = 2e-12
Identities = 83/286 (29%), Positives = 100/286 (34%), Gaps = 49/286 (17%)
Query: 412 NKMAQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPP--------- 462
N +P + +PG P P P G Q + P GP Q P
Sbjct: 409 NPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPP-GPQGATGPLGPKGQTGEPGIAGFKGEQ 467
Query: 463 -PQGGP----PQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPA--------GSPLPQRLP 509
P+G P PQ PGP + R P G + +GPP G P L
Sbjct: 468 GPKGEPGPAGPQGAPGPAGEEGKRGARGEPGG---VGPIGPPGERGAPGNRGFPGQDGLA 524
Query: 510 SPTSAP-QQPASQAAPPTQGQGRQSRPVAGG-PGAPPAARPPASPSPQRQAGPPQATRQT 567
P AP ++ S A P G RP G PGA P PQ + GP A +
Sbjct: 525 GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGED 584
Query: 568 SVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPP----------T 617
GP P+ + PG PGP G + +AG G P
Sbjct: 585 GRPGPPGPQGARGQPG-------VMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGE 637
Query: 618 TQQPRPSGP-GPAGRPKPQLAQKPS--QDVP-PPATAAAGGPPHPQ 659
T P GP GPAG Q A PS Q +P PP GG P Q
Sbjct: 638 TGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQ 683
Score = 70.5 bits (171), Expect = 5e-12
Identities = 79/255 (30%), Positives = 96/255 (37%), Gaps = 30/255 (11%)
Query: 430 RGSHGQTPSPGALPLGRQTSQQPAGPPAQQ----RPPPQGGPPQPGP----GPQRQGPPL 481
RG G SPG P G + G P + P G P PGP GPQ PL
Sbjct: 392 RGEPGTPGSPG--PAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPL 449
Query: 482 QQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPG 541
P+GQ G+ G P+ P P A Q A A +G + P GP
Sbjct: 450 G----PKGQTGEPGIAGFKGEQGPKGEPGP--AGPQGAPGPAGEEGKRGARGEPGGVGPI 503
Query: 542 APPAARPPAS----PSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGP 597
PP R P AGP A + SG A PK + PG R G P PG
Sbjct: 504 GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPG---RPGEPGL-PGA 559
Query: 598 AGPTRQASQAGPVPRTGPPTT--QQPRPSGPGPAG-RPKPQLAQKP---SQDVPPPATAA 651
G T + AGP + GP + RP PGP G R +P + P + P
Sbjct: 560 RGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGE 619
Query: 652 AGGPPHPQLKASPAQ 666
G P P L+ P +
Sbjct: 620 KGLPGAPGLRGLPGK 634
Score = 69.3 bits (168), Expect = 1e-11
Identities = 71/248 (28%), Positives = 86/248 (34%), Gaps = 40/248 (16%)
Query: 416 QALPRQRQRDASPG-RGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQ---PG 471
Q L QR PG RG G PG P G Q G + PP GPP P
Sbjct: 974 QGLAGQRGIVGLPGQRGERGFPGLPG--PSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA 1031
Query: 472 PGPQRQGPPLQQRPPPQ-------GQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAP 524
P R+G P PP + G + +G G+P P P P + +
Sbjct: 1032 GEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEA 1091
Query: 525 PTQGQGRQSRPVAG----GPGAPPAARPPASPSPQRQA-------------GPPQATRQT 567
QG S P GP P + A +R GPP +
Sbjct: 1092 GAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQ 1151
Query: 568 SVSGPAPP---KASGAPPGGQQRQGP-----PQKPPGPAGPTRQASQAGPVPRTGPPTTQ 619
SGPA P + P G + G P PPGP G + + AGP GPP
Sbjct: 1152 GASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP--G 1209
Query: 620 QPRPSGPG 627
P P GPG
Sbjct: 1210 PPGPPGPG 1217
Score = 64.3 bits (155), Expect = 3e-10
Identities = 76/256 (29%), Positives = 89/256 (34%), Gaps = 34/256 (13%)
Query: 431 GSHGQTPSPGALPL-GRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPP-------LQ 482
G G+ +PG G+ P G P ++ P GP P R G P L
Sbjct: 504 GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLT 563
Query: 483 QRPP---PQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGG 539
RP PQG+ SG G P P P P A QP P +G G
Sbjct: 564 GRPGDAGPQGKVGPSGAPGEDGRPGP---PGPQGARGQPGVMGFPGPKGAN-------GE 613
Query: 540 PGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPP--QKPPGP 597
PG P +P + G P +T +GP P G Q GP Q PGP
Sbjct: 614 PGKAGEKGLPGAPGLR---GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGP 670
Query: 598 AGPTRQASQAGP--VP-RTGPPTTQQPRPSG--PGPAGRPKPQLAQKPSQDVPPPATAAA 652
GP + + G VP G P PR PG G P Q Q P P T
Sbjct: 671 PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPR---GLPGTPGT 727
Query: 653 GGPPHPQLKASPAQAQ 668
GP A P AQ
Sbjct: 728 DGPKGASGPAGPPGAQ 743
Score = 62.8 bits (151), Expect = 1e-09
Identities = 63/205 (30%), Positives = 73/205 (35%), Gaps = 30/205 (14%)
Query: 457 AQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQ 516
A +P P+G +PG GP + P PQG G G + P P
Sbjct: 96 ASGQPGPKGQKGEPGDIKDIVGP--KGPPGPQGPAGEQGPRGDRGDKGEKGAPGP----- 148
Query: 517 QPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPK 576
+GR P G PG P PP P P G A ++G K
Sbjct: 149 ------------RGRDGEP--GTPGNPGPPGPPGPPGPPGLGGNFAA----QMAGGFDEK 190
Query: 577 ASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQ-QPRPSGP-GPAGRPKP 634
A GA G Q P P GP GP A GP G P +P SGP GP G P P
Sbjct: 191 AGGAQLGVMQG---PMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGP 247
Query: 635 QLAQKPSQDVPPPATAAAGGPPHPQ 659
+ P A GPP PQ
Sbjct: 248 PGKPGDDGEAGKPGKAGERGPPGPQ 272
Score = 60.1 bits (144), Expect = 7e-09
Identities = 73/255 (28%), Positives = 83/255 (32%), Gaps = 48/255 (18%)
Query: 418 LPRQRQRDASPG----RGSHGQTPSPGAL-------PLGRQTSQQPAGPPAQQRPPPQGG 466
LP QR PG G G+ +PGA P+G PAG P ++ P G
Sbjct: 985 LPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADG 1044
Query: 467 PP-------------QPGP--GPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSP 511
PP + G P GPP P P G G AG+ P P
Sbjct: 1045 PPGRDGAAGVKGDRGETGAVGAPGAPGPP--GSPGPAGPTGKQGDRGEAGAQGPMGPSGP 1102
Query: 512 TSA-----PQQPASQAA----PPTQG-------QGRQSRPVAGGPGAPPAARPPASPSPQ 555
A PQ P P +G G Q P GP A PA PS
Sbjct: 1103 AGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGP 1162
Query: 556 RQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGP--PQKPPGPAGPTRQASQAGPVPRT 613
R GPP + G PPG + R G P PPG GP GP
Sbjct: 1163 R--GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDM 1220
Query: 614 GPPTTQQPRPSGPGP 628
PR GP P
Sbjct: 1221 SAFAGLGPREKGPDP 1235
Score = 40.8 bits (94), Expect = 0.004
Identities = 26/65 (40%), Positives = 29/65 (44%), Gaps = 13/65 (20%)
Query: 431 GSHGQTPSPGAL----PLGRQTSQQPAGPPAQQRPPPQGGPPQP--------GPGPQRQG 478
G G PG + P GR PAGPP PP GPP P G GP+ +G
Sbjct: 1173 GKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKG 1232
Query: 479 P-PLQ 482
P PLQ
Sbjct: 1233 PDPLQ 1237
Score = 39.7 bits (91), Expect = 0.009
Identities = 29/93 (31%), Positives = 34/93 (36%), Gaps = 16/93 (17%)
Query: 554 PQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPT------------ 601
P + P T + SG PK PG + P+ PPGP GP
Sbjct: 81 PFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDK 140
Query: 602 RQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKP 634
+ GP R G P T P PGP G P P
Sbjct: 141 GEKGAPGPRGRDGEPGT----PGNPGPPGPPGP 169
Score = 33.1 bits (74), Expect = 0.85
Identities = 27/94 (28%), Positives = 34/94 (36%), Gaps = 18/94 (19%)
Query: 572 PAPPKASGAPPGGQQRQGPPQK------PPGPAGPTRQASQAGPVPRTGPPTTQQPRPSG 625
P + PG + ++G P P GP GP A + GP G +
Sbjct: 90 PTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRG----DKGEKGA 145
Query: 626 PGPAGRP-KPQLAQKPSQDVPPPATAAAGGPPHP 658
PGP GR +P P PP GPP P
Sbjct: 146 PGPRGRDGEPGTPGNPGPPGPP-------GPPGP 172
Score = 31.2 bits (69), Expect = 3.2
Identities = 16/54 (29%), Positives = 24/54 (44%)
Query: 23 TDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGGF 76
T + P+ P G +PGP A+ + P A +A +PG +G GF
Sbjct: 380 TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF 433
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 89.0 bits (219), Expect = 1e-17
Identities = 80/287 (27%), Positives = 98/287 (34%), Gaps = 60/287 (20%)
Query: 430 RGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQR----P 485
+G+ G + PG G Q PAGPP ++ P GP P QG Q+ P
Sbjct: 860 KGARGDSGPPGRA--GEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLP 917
Query: 486 PPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAP----PTQGQGRQSRPVAGGP- 540
+G++ GL P+G P Q P + P P P GR+ P A GP
Sbjct: 918 GQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPP 977
Query: 541 ------------------GAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPP 582
GAP A PP SP P G + GP P
Sbjct: 978 GRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGAR 1037
Query: 583 GGQQRQGPP-----------------------QKPPGPAGPTRQASQAGPVPRTGPPTTQ 619
G Q QGP Q PGP GP+ +GP +GP
Sbjct: 1038 GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPP 1097
Query: 620 QP-RPSG-------PGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHP 658
P PSG PGP G P P+ + PP GPP P
Sbjct: 1098 GPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGP 1144
Score = 86.3 bits (212), Expect = 8e-17
Identities = 79/254 (31%), Positives = 93/254 (36%), Gaps = 38/254 (14%)
Query: 429 GRGSHGQTPSPGALPLGRQTSQQPAGPP-------AQQRPPPQGGPPQPGPGPQRQGPPL 481
GRG G PG P G + GPP A+ P +G PGP P
Sbjct: 715 GRGLTGPIGPPG--PAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGA 772
Query: 482 QQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPG 541
+P +G+Q +G AG+P PQ PS PQ P P +G Q P G G
Sbjct: 773 DGQPGAKGEQGEAGQKGDAGAPGPQG-PSGAPGPQGPTG-VTGPKGARGAQGPP--GATG 828
Query: 542 APPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPP--QKPPGPAG 599
P AA P GPP + GP + PPG R G P Q P GP G
Sbjct: 829 FPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPG---RAGEPGLQGPAGPPG 885
Query: 600 PTRQASQAGPVPRTGPPTTQ-----------------QPRPSGPGPAGRPKPQLAQKPSQ 642
+ GP GPP Q + P PGP+G P Q A S
Sbjct: 886 EKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASG 945
Query: 643 DVPPPATAAAGGPP 656
D PP GPP
Sbjct: 946 DRGPPGPV---GPP 956
Score = 77.4 bits (189), Expect = 4e-14
Identities = 65/217 (29%), Positives = 81/217 (37%), Gaps = 18/217 (8%)
Query: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPP-QPGPGPQRQ 477
P + SPG P LP G + PAG + Q GP PGP
Sbjct: 236 PGVKGESGSPGENGSPGPMGPRGLP-GERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAG 294
Query: 478 GPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVA 537
GP P +G+ +G P G+ P+ P +P + P T G
Sbjct: 295 GPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDG----IPGAK 350
Query: 538 GGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPG--GQQRQGPPQKPP 595
G GAP A P P P+ GP AT GP PK PG G + + P+ P
Sbjct: 351 GSAGAPGIAGAPGFPGPRGPPGPQGAT------GPLGPKGQTGEPGIAGFKGEQGPKGEP 404
Query: 596 GPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRP 632
GPAGP AG + G + P G GP G P
Sbjct: 405 GPAGPQGAPGPAGEEGKRG----ARGEPGGVGPIGPP 437
Score = 75.5 bits (184), Expect = 1e-13
Identities = 86/295 (29%), Positives = 101/295 (34%), Gaps = 59/295 (20%)
Query: 412 NKMAQALPRQRQRDASPGR----GSHGQTPSPGALPLGRQTSQQPAGP----------PA 457
+K + P R RD PG G G PG LG + Q AG
Sbjct: 70 DKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV 129
Query: 458 QQRPP-PQG--GPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSA 514
Q P P G GPP P P QG Q P G+ +SG P G P P P
Sbjct: 130 MQGPMGPMGPRGPPGPAGAPGPQG--FQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGE 187
Query: 515 PQQP--ASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSG- 571
+P A + PP R G PG P + +AG P ++ G
Sbjct: 188 AGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGE 247
Query: 572 ---PAPPKASGAPPGGQQRQGP--------------PQKPPGPAGPTR---------QAS 605
P P G P G + R GP P PPGP GP
Sbjct: 248 NGSPGPMGPRGLP-GERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKG 306
Query: 606 QAGPVPRTGPPTTQQPR-----PSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGP 655
+AGP GP Q PR P PGPAG + P D P A +AG P
Sbjct: 307 EAGPTGARGPEGAQGPRGEPGTPGSPGPAG-----ASGNPGTDGIPGAKGSAGAP 356
Score = 75.1 bits (183), Expect = 2e-13
Identities = 71/239 (29%), Positives = 86/239 (35%), Gaps = 41/239 (17%)
Query: 428 PGR-GSHGQTPSPG-ALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRP 485
PG+ G G PG A P G + Q GP Q P GPP G P QG P +
Sbjct: 563 PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGA 622
Query: 486 P----PQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPG 541
P P+G++ G GSP Q L P P P G A GP
Sbjct: 623 PGLVGPRGERGFPG---ERGSPGAQGLQGPRGLPGTP-----------GTDGPKGASGPA 668
Query: 542 APPAARPP----ASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGP 597
PP A+ P P + AG G P+ + GG+ G P PPGP
Sbjct: 669 GPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTG-PIGPPGP 727
Query: 598 AGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPP 656
AG + + GP PGPAG + A + PP A GPP
Sbjct: 728 AGANGEKGEVGP----------------PGPAGSAGARGAPGERGETGPPGPAGFAGPP 770
Score = 74.7 bits (182), Expect = 3e-13
Identities = 75/246 (30%), Positives = 85/246 (34%), Gaps = 27/246 (10%)
Query: 430 RGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQG 489
RG G+ SPGA G Q + G P P GP P P QGPP Q P G
Sbjct: 632 RGFPGERGSPGAQ--GLQGPRGLPGTPGTDGPKGASGPAGP---PGAQGPPGLQGMP--G 684
Query: 490 QQHLSGLGPPAGSPLPQRLPSPTSAPQQ------------PASQAAPPTQGQGRQSRPV- 536
++ +G+ P G P AP + P A +G+ P
Sbjct: 685 ERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAG 744
Query: 537 -AGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPP 595
AG GAP P P AGPP A Q G G QG P P
Sbjct: 745 SAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQG-PSGAP 803
Query: 596 GPAGPTRQASQAGPVPRTGPP-TTQQPRPSG----PGPAGRPKPQLAQKPSQDVPPPATA 650
GP GPT G GPP T P +G PG G P P PS P
Sbjct: 804 GPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGAR 863
Query: 651 AAGGPP 656
GPP
Sbjct: 864 GDSGPP 869
Score = 73.6 bits (179), Expect = 6e-13
Identities = 73/252 (28%), Positives = 89/252 (35%), Gaps = 21/252 (8%)
Query: 430 RGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQG 489
RG G+ +PG P GR G P PP GPP G G G
Sbjct: 68 RGDKGEKGAPG--PRGRDGEPGTPGNPGPPGPPGPPGPP--GLGGNFAAQMAGGFDEKAG 123
Query: 490 QQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPP 549
L + P G P+ P P AP Q P G+ S P+ GP PP PP
Sbjct: 124 GAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPM--GPRGPPG--PP 179
Query: 550 ASPSPQRQAGPPQATRQTSVSGPAPPKA-SGAP--PGGQQRQGPP--QKPPGPAGPTRQA 604
P +AG P + GP + G P PG + +G P G AG
Sbjct: 180 GKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVK 239
Query: 605 SQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQ-------KPSQDVPPPATAAAGGPPH 657
++G G P PR PG GR P A +P PP AGGP
Sbjct: 240 GESGSPGENGSPGPMGPRGL-PGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGF 298
Query: 658 PQLKASPAQAQP 669
P + +A P
Sbjct: 299 PGAPGAKGEAGP 310
Score = 72.0 bits (175), Expect = 2e-12
Identities = 83/286 (29%), Positives = 100/286 (34%), Gaps = 49/286 (17%)
Query: 412 NKMAQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPP--------- 462
N +P + +PG P P P G Q + P GP Q P
Sbjct: 340 NPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPP-GPQGATGPLGPKGQTGEPGIAGFKGEQ 398
Query: 463 -PQGGP----PQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPA--------GSPLPQRLP 509
P+G P PQ PGP + R P G + +GPP G P L
Sbjct: 399 GPKGEPGPAGPQGAPGPAGEEGKRGARGEPGG---VGPIGPPGERGAPGNRGFPGQDGLA 455
Query: 510 SPTSAP-QQPASQAAPPTQGQGRQSRPVAGG-PGAPPAARPPASPSPQRQAGPPQATRQT 567
P AP ++ S A P G RP G PGA P PQ + GP A +
Sbjct: 456 GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGED 515
Query: 568 SVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPP----------T 617
GP P+ + PG PGP G + +AG G P
Sbjct: 516 GRPGPPGPQGARGQPG-------VMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGE 568
Query: 618 TQQPRPSGP-GPAGRPKPQLAQKPS--QDVP-PPATAAAGGPPHPQ 659
T P GP GPAG Q A PS Q +P PP GG P Q
Sbjct: 569 TGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQ 614
Score = 70.5 bits (171), Expect = 5e-12
Identities = 79/255 (30%), Positives = 96/255 (37%), Gaps = 30/255 (11%)
Query: 430 RGSHGQTPSPGALPLGRQTSQQPAGPPAQQ----RPPPQGGPPQPGP----GPQRQGPPL 481
RG G SPG P G + G P + P G P PGP GPQ PL
Sbjct: 323 RGEPGTPGSPG--PAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPL 380
Query: 482 QQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPG 541
P+GQ G+ G P+ P P A Q A A +G + P GP
Sbjct: 381 G----PKGQTGEPGIAGFKGEQGPKGEPGP--AGPQGAPGPAGEEGKRGARGEPGGVGPI 434
Query: 542 APPAARPPAS----PSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGP 597
PP R P AGP A + SG A PK + PG R G P PG
Sbjct: 435 GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPG---RPGEPGL-PGA 490
Query: 598 AGPTRQASQAGPVPRTGPPTT--QQPRPSGPGPAG-RPKPQLAQKP---SQDVPPPATAA 651
G T + AGP + GP + RP PGP G R +P + P + P
Sbjct: 491 RGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGE 550
Query: 652 AGGPPHPQLKASPAQ 666
G P P L+ P +
Sbjct: 551 KGLPGAPGLRGLPGK 565
Score = 69.3 bits (168), Expect = 1e-11
Identities = 71/248 (28%), Positives = 86/248 (34%), Gaps = 40/248 (16%)
Query: 416 QALPRQRQRDASPG-RGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQ---PG 471
Q L QR PG RG G PG P G Q G + PP GPP P
Sbjct: 905 QGLAGQRGIVGLPGQRGERGFPGLPG--PSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA 962
Query: 472 PGPQRQGPPLQQRPPPQ-------GQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAP 524
P R+G P PP + G + +G G+P P P P + +
Sbjct: 963 GEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEA 1022
Query: 525 PTQGQGRQSRPVAG----GPGAPPAARPPASPSPQRQA-------------GPPQATRQT 567
QG S P GP P + A +R GPP +
Sbjct: 1023 GAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQ 1082
Query: 568 SVSGPAPP---KASGAPPGGQQRQGP-----PQKPPGPAGPTRQASQAGPVPRTGPPTTQ 619
SGPA P + P G + G P PPGP G + + AGP GPP
Sbjct: 1083 GASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP--G 1140
Query: 620 QPRPSGPG 627
P P GPG
Sbjct: 1141 PPGPPGPG 1148
Score = 64.3 bits (155), Expect = 3e-10
Identities = 76/256 (29%), Positives = 89/256 (34%), Gaps = 34/256 (13%)
Query: 431 GSHGQTPSPGALPL-GRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPP-------LQ 482
G G+ +PG G+ P G P ++ P GP P R G P L
Sbjct: 435 GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLT 494
Query: 483 QRPP---PQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGG 539
RP PQG+ SG G P P P P A QP P +G G
Sbjct: 495 GRPGDAGPQGKVGPSGAPGEDGRPGP---PGPQGARGQPGVMGFPGPKGAN-------GE 544
Query: 540 PGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPP--QKPPGP 597
PG P +P + G P +T +GP P G Q GP Q PGP
Sbjct: 545 PGKAGEKGLPGAPGLR---GLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGP 601
Query: 598 AGPTRQASQAGP--VP-RTGPPTTQQPRPSG--PGPAGRPKPQLAQKPSQDVPPPATAAA 652
GP + + G VP G P PR PG G P Q Q P P T
Sbjct: 602 PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPR---GLPGTPGT 658
Query: 653 GGPPHPQLKASPAQAQ 668
GP A P AQ
Sbjct: 659 DGPKGASGPAGPPGAQ 674
Score = 63.2 bits (152), Expect = 8e-10
Identities = 63/195 (32%), Positives = 77/195 (39%), Gaps = 27/195 (13%)
Query: 477 QGPPLQQRPPPQGQQHLSG----LGPPAGSPLPQRLPSPTSAPQ----QPASQAAPPTQG 528
QG ++Q P P+GQ+ G + P G P PQ P+ P+ + AP +G
Sbjct: 24 QGQDVRQ-PGPKGQKGEPGDIKDIVGPKGPPGPQG-PAGEQGPRGDRGDKGEKGAPGPRG 81
Query: 529 QGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQ--ATRQTSVSGPAPPKASGAPPGGQQ 586
+ G PG P PP P P GPP ++G KA GA G Q
Sbjct: 82 RD-------GEPGTPGNPGPPGPPGPP---GPPGLGGNFAAQMAGGFDEKAGGAQLGVMQ 131
Query: 587 RQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQ-QPRPSGP-GPAGRPKPQLAQKPSQDV 644
P P GP GP A GP G P +P SGP GP G P P +
Sbjct: 132 G---PMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEA 188
Query: 645 PPPATAAAGGPPHPQ 659
P A GPP PQ
Sbjct: 189 GKPGKAGERGPPGPQ 203
Score = 60.1 bits (144), Expect = 7e-09
Identities = 73/255 (28%), Positives = 83/255 (32%), Gaps = 48/255 (18%)
Query: 418 LPRQRQRDASPG----RGSHGQTPSPGAL-------PLGRQTSQQPAGPPAQQRPPPQGG 466
LP QR PG G G+ +PGA P+G PAG P ++ P G
Sbjct: 916 LPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADG 975
Query: 467 PP-------------QPGP--GPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSP 511
PP + G P GPP P P G G AG+ P P
Sbjct: 976 PPGRDGAAGVKGDRGETGAVGAPGAPGPP--GSPGPAGPTGKQGDRGEAGAQGPMGPSGP 1033
Query: 512 TSA-----PQQPASQAA----PPTQG-------QGRQSRPVAGGPGAPPAARPPASPSPQ 555
A PQ P P +G G Q P GP A PA PS
Sbjct: 1034 AGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGP 1093
Query: 556 RQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGP--PQKPPGPAGPTRQASQAGPVPRT 613
R GPP + G PPG + R G P PPG GP GP
Sbjct: 1094 R--GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDM 1151
Query: 614 GPPTTQQPRPSGPGP 628
PR GP P
Sbjct: 1152 SAFAGLGPREKGPDP 1166
Score = 40.8 bits (94), Expect = 0.004
Identities = 26/65 (40%), Positives = 29/65 (44%), Gaps = 13/65 (20%)
Query: 431 GSHGQTPSPGAL----PLGRQTSQQPAGPPAQQRPPPQGGPPQP--------GPGPQRQG 478
G G PG + P GR PAGPP PP GPP P G GP+ +G
Sbjct: 1104 GKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKG 1163
Query: 479 P-PLQ 482
P PLQ
Sbjct: 1164 PDPLQ 1168
Score = 31.2 bits (69), Expect = 3.2
Identities = 16/54 (29%), Positives = 24/54 (44%)
Query: 23 TDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGGF 76
T + P+ P G +PGP A+ + P A +A +PG +G GF
Sbjct: 311 TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF 364
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 86.3 bits (212), Expect = 8e-17
Identities = 85/266 (31%), Positives = 110/266 (41%), Gaps = 41/266 (15%)
Query: 418 LPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQ 477
+P+ R A+ S G P P P GR TS +P PP+ G P P PG R
Sbjct: 108 MPKLRST-ANRDNDSGGSRP-PLLPPGGRSTSAKPFSPPSGP-----GRFPVPSPG-HRS 159
Query: 478 GPPLQQR---PPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSR 534
GPP QR PPP+ P GS P +P P + +P Q++P +G S
Sbjct: 160 GPPEPQRNRMPPPR---------PDVGSK-PDSIPPPVPSTPRPI-QSSPHNRG----SP 204
Query: 535 PVAGGPGAP-PAARPPASPSPQRQAGPPQATRQTSVSGPAP----PKASGAPPGGQQRQG 589
PV GGP P P PP P + A + RQ+ +S +P P P +
Sbjct: 205 PVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKP 264
Query: 590 PPQKPPGPAGPT--RQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPP 647
PP PP P+ R+A P PP PRPS A P P PS+ PPP
Sbjct: 265 PPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPP----PPSRPGPPP 320
Query: 648 ATAAAGG----PPHPQLKASPAQAQP 669
++ G P PQ S + + P
Sbjct: 321 LPPSSSGNDETPRLPQRNLSLSSSTP 346
Score = 69.3 bits (168), Expect = 1e-11
Identities = 80/299 (26%), Positives = 101/299 (33%), Gaps = 83/299 (27%)
Query: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQ--- 475
P ++ P R G P P+ + P + PP GGP QP PGP
Sbjct: 162 PEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPP 221
Query: 476 --------------RQGP-----PLQQRPP--PQGQQHLSGLGPPAGSPLPQRLPS--PT 512
RQ P P RPP P + L PP P+ R PS
Sbjct: 222 FPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNR-PSIHRE 280
Query: 513 SAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAG----PPQATRQTS 568
+ P P PP R S P PP +RP P P +G P R S
Sbjct: 281 AVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLS 340
Query: 569 VSGPAPP-----KASGAPPGGQQRQGPPQK-PPGPAGP-------TRQAS---------- 605
+S PP ++ PP +R PP + PPG +GP +R S
Sbjct: 341 LSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQ 400
Query: 606 ----------QAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGG 654
++GP P P RPS AG P P PPP+T+ G
Sbjct: 401 LPSRSGVDSPRSGPRPPLPP-----DRPS----AGAPPP----------PPPSTSIRNG 440
Score = 48.5 bits (114), Expect = 2e-05
Identities = 56/229 (24%), Positives = 72/229 (31%), Gaps = 66/229 (28%)
Query: 489 GQQHLSGLGPPAGSPLPQ----RLPSPTSAPQQPASQAAP--PTQGQGRQSRPVA--GGP 540
G G GPP L Q +L S + P P G+ ++P + GP
Sbjct: 88 GGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGP 147
Query: 541 GAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGP 600
G P PSP ++GPP+ P+ + PP P P P
Sbjct: 148 GRFPV------PSPGHRSGPPE------------PQRNRMPPPRPDVGSKPDSIPPPVPS 189
Query: 601 TRQASQAGPVPRTGPPTTQQPRPSGPGPAGRP---------------------------K 633
T + Q+ P R PP PR PGP P +
Sbjct: 190 TPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNR 249
Query: 634 PQLAQKPSQ---DVPPPATAAAGG----------PPHPQLKASPAQAQP 669
P L PS+ D PPP G PP PQ P + P
Sbjct: 250 PPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTP 298
Score = 48.5 bits (114), Expect = 2e-05
Identities = 63/237 (26%), Positives = 78/237 (32%), Gaps = 76/237 (32%)
Query: 424 RDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPP-------------------- 463
R+A P P + P +SQ P PP RP P
Sbjct: 279 REAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRN 338
Query: 464 ----QGGPPQPGPGPQRQG---PPLQQRPPPQGQQHLSGLGP-----------------P 499
PP P PG R G PP +RPPP + GP P
Sbjct: 339 LSLSSSTPPLPSPG--RSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALP 396
Query: 500 AGSPLPQR--LPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARP-----PASP 552
A LP R + SP S P+ P PP RP AG P PP + SP
Sbjct: 397 ATPQLPSRSGVDSPRSGPRPP----LPP-------DRPSAGAPPPPPPSTSIRNGFQDSP 445
Query: 553 -----------SPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQ-GPPQKPPGP 597
P PP+ QT+ S P+ + + G +R+ G P PP P
Sbjct: 446 CEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPIP 502
Score = 35.0 bits (79), Expect = 0.22
Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 7/51 (13%)
Query: 29 QPPPPPPGAHSPGATPGPGTATAERSSGVAP-------AASPAAPSPGSSG 72
Q PPPPP PG P P +++ + P +++P PSPG SG
Sbjct: 305 QAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG 355
Score = 31.6 bits (70), Expect = 2.5
Identities = 21/61 (34%), Positives = 24/61 (39%), Gaps = 8/61 (13%)
Query: 18 PNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAA-----PSPGSSG 72
P G + R PPPPP + P P P T SS P P + P P SS
Sbjct: 270 PVGNRPSIHREAVPPPPPQNNKP---PVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSS 326
Query: 73 G 73
G
Sbjct: 327 G 327
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 86.3 bits (212), Expect = 8e-17
Identities = 85/266 (31%), Positives = 110/266 (41%), Gaps = 41/266 (15%)
Query: 418 LPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQ 477
+P+ R A+ S G P P P GR TS +P PP+ G P P PG R
Sbjct: 108 MPKLRST-ANRDNDSGGSRP-PLLPPGGRSTSAKPFSPPSGP-----GRFPVPSPG-HRS 159
Query: 478 GPPLQQR---PPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSR 534
GPP QR PPP+ P GS P +P P + +P Q++P +G S
Sbjct: 160 GPPEPQRNRMPPPR---------PDVGSK-PDSIPPPVPSTPRPI-QSSPHNRG----SP 204
Query: 535 PVAGGPGAP-PAARPPASPSPQRQAGPPQATRQTSVSGPAP----PKASGAPPGGQQRQG 589
PV GGP P P PP P + A + RQ+ +S +P P P +
Sbjct: 205 PVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKP 264
Query: 590 PPQKPPGPAGPT--RQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPP 647
PP PP P+ R+A P PP PRPS A P P PS+ PPP
Sbjct: 265 PPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPP----PPSRPGPPP 320
Query: 648 ATAAAGG----PPHPQLKASPAQAQP 669
++ G P PQ S + + P
Sbjct: 321 LPPSSSGNDETPRLPQRNLSLSSSTP 346
Score = 69.3 bits (168), Expect = 1e-11
Identities = 80/299 (26%), Positives = 101/299 (33%), Gaps = 83/299 (27%)
Query: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQ--- 475
P ++ P R G P P+ + P + PP GGP QP PGP
Sbjct: 162 PEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPP 221
Query: 476 --------------RQGP-----PLQQRPP--PQGQQHLSGLGPPAGSPLPQRLPS--PT 512
RQ P P RPP P + L PP P+ R PS
Sbjct: 222 FPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNR-PSIHRE 280
Query: 513 SAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAG----PPQATRQTS 568
+ P P PP R S P PP +RP P P +G P R S
Sbjct: 281 AVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLS 340
Query: 569 VSGPAPP-----KASGAPPGGQQRQGPPQK-PPGPAGP-------TRQAS---------- 605
+S PP ++ PP +R PP + PPG +GP +R S
Sbjct: 341 LSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQ 400
Query: 606 ----------QAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGG 654
++GP P P RPS AG P P PPP+T+ G
Sbjct: 401 LPSRSGVDSPRSGPRPPLPP-----DRPS----AGAPPP----------PPPSTSIRNG 440
Score = 48.5 bits (114), Expect = 2e-05
Identities = 56/229 (24%), Positives = 72/229 (31%), Gaps = 66/229 (28%)
Query: 489 GQQHLSGLGPPAGSPLPQ----RLPSPTSAPQQPASQAAP--PTQGQGRQSRPVA--GGP 540
G G GPP L Q +L S + P P G+ ++P + GP
Sbjct: 88 GGGSFGGGGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGP 147
Query: 541 GAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGP 600
G P PSP ++GPP+ P+ + PP P P P
Sbjct: 148 GRFPV------PSPGHRSGPPE------------PQRNRMPPPRPDVGSKPDSIPPPVPS 189
Query: 601 TRQASQAGPVPRTGPPTTQQPRPSGPGPAGRP---------------------------K 633
T + Q+ P R PP PR PGP P +
Sbjct: 190 TPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNR 249
Query: 634 PQLAQKPSQ---DVPPPATAAAGG----------PPHPQLKASPAQAQP 669
P L PS+ D PPP G PP PQ P + P
Sbjct: 250 PPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTP 298
Score = 48.5 bits (114), Expect = 2e-05
Identities = 63/237 (26%), Positives = 78/237 (32%), Gaps = 76/237 (32%)
Query: 424 RDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPP-------------------- 463
R+A P P + P +SQ P PP RP P
Sbjct: 279 REAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRN 338
Query: 464 ----QGGPPQPGPGPQRQG---PPLQQRPPPQGQQHLSGLGP-----------------P 499
PP P PG R G PP +RPPP + GP P
Sbjct: 339 LSLSSSTPPLPSPG--RSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALP 396
Query: 500 AGSPLPQR--LPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARP-----PASP 552
A LP R + SP S P+ P PP RP AG P PP + SP
Sbjct: 397 ATPQLPSRSGVDSPRSGPRPP----LPP-------DRPSAGAPPPPPPSTSIRNGFQDSP 445
Query: 553 -----------SPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQ-GPPQKPPGP 597
P PP+ QT+ S P+ + + G +R+ G P PP P
Sbjct: 446 CEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPIP 502
Score = 35.0 bits (79), Expect = 0.22
Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 7/51 (13%)
Query: 29 QPPPPPPGAHSPGATPGPGTATAERSSGVAP-------AASPAAPSPGSSG 72
Q PPPPP PG P P +++ + P +++P PSPG SG
Sbjct: 305 QAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG 355
Score = 31.6 bits (70), Expect = 2.5
Identities = 21/61 (34%), Positives = 24/61 (39%), Gaps = 8/61 (13%)
Query: 18 PNGYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAA-----PSPGSSG 72
P G + R PPPPP + P P P T SS P P + P P SS
Sbjct: 270 PVGNRPSIHREAVPPPPPQNNKP---PVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSS 326
Query: 73 G 73
G
Sbjct: 327 G 327
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 86.3 bits (212), Expect = 8e-17
Identities = 87/308 (28%), Positives = 117/308 (37%), Gaps = 58/308 (18%)
Query: 407 VELVVNKMAQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGP---------PA 457
+E +N+ LP + SP +P P A L + PA P P
Sbjct: 430 LEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPL 489
Query: 458 QQ---RPPPQGGPPQPGP-----GPQRQ---GPPLQQRPPPQGQQHLSGLGPPAGSPL-P 505
++ PPP+ P P P P + PP + P P + LS PP SPL P
Sbjct: 490 EESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLS--PPPEASPLSP 547
Query: 506 QRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATR 565
SP S P + + PP R S P P +PP P SP PP+A+R
Sbjct: 548 PFEESPLSPPPEELPTSPPPE--ASRLSPPPEESPMSPPPEESPMSP-------PPEASR 598
Query: 566 -----QTSVSGPAPPKASGAPPGGQQRQGP-----PQKPP---GPAGPTRQASQAGPVP- 611
+ S P P ++ +PP R P P PP P P + S+ P+P
Sbjct: 599 LFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPV 658
Query: 612 --RTGPPTTQQP-------RPSGPGP-AGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLK 661
R PP + P P+ P P A R P P+ PPP + A PP L
Sbjct: 659 VSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTS--PPPEDSPASPPPEDSLM 716
Query: 662 ASPAQAQP 669
+ P + P
Sbjct: 717 SLPLEESP 724
Score = 74.3 bits (181), Expect = 3e-13
Identities = 72/268 (26%), Positives = 100/268 (37%), Gaps = 31/268 (11%)
Query: 427 SPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQ-RQGPPLQQRP 485
SP T P AL + Q QP G P + GP Q P + G L+ +
Sbjct: 373 SPPEPGDTPTDEPDALYVACQG--QPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQL 430
Query: 486 PPQGQQHLSGLGPPAGSPL-PQRLPSPTSAPQQPASQAAPPTQGQGRQ-------SRPVA 537
+ + L PP SPL P SPTS P + + + PP + SRP+
Sbjct: 431 EAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLE 490
Query: 538 GGPGAPPAARPPASPSPQR--------------QAGPPQATRQTSVSGPAPPKASGAPPG 583
P +PP P SP P+ + PP +T +S PP+AS P
Sbjct: 491 ESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLS--PPPEASPLSPP 548
Query: 584 GQQRQGPPQKPPGPAGPTRQASQAGPVPRTGP--PTTQQPRPSGPGPAGRPKPQLAQKPS 641
++ P P P +AS+ P P P P ++ S P A R P + P
Sbjct: 549 FEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPL 608
Query: 642 QDVPPPATAAAGGPPHPQLKASPAQAQP 669
PPP + PP + P + P
Sbjct: 609 S--PPPEESPLSPPPEASRLSPPPEDSP 634
Score = 65.9 bits (159), Expect = 1e-10
Identities = 88/293 (30%), Positives = 106/293 (36%), Gaps = 70/293 (23%)
Query: 418 LPRQRQRDAS----PGRGSHGQTPS-----------------------PGALPLGRQTSQ 450
LP Q+Q+ S G GSHGQ S PG++ Q
Sbjct: 4097 LPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQ 4156
Query: 451 QPA-GPPAQQRPPPQGGPPQPGPGPQR-QGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRL 508
QP P Q PQ PP+PGP Q QG P P GQ G A +P + L
Sbjct: 4157 QPMLERPMQNNTGPQ--PPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHL 4214
Query: 509 PSPTSAPQQPA---------SQAA---PPTQGQGRQSRPVAGGPGAPPAARPPASPSPQR 556
SP Q A SQA PP Q G Q+ P+ G G +P P
Sbjct: 4215 -SPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGC----QPQLGGFPGP 4269
Query: 557 QAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPP 616
Q GP Q +GP P QGPP+ P P G GPV T PP
Sbjct: 4270 QTGPLQELG----AGPRP-------------QGPPRLP-APPGALSTGPVLGPVHPTPPP 4311
Query: 617 TTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQP 669
++ Q P P P QL P++ PP P P L+ P + P
Sbjct: 4312 SSPQ-EPKRPSQLPSPSSQL---PTEAQLPPTHPGTPKPQGPTLEPPPGRVSP 4360
Score = 63.2 bits (152), Expect = 8e-10
Identities = 71/282 (25%), Positives = 98/282 (34%), Gaps = 39/282 (13%)
Query: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQR------------PPPQGG 466
P + SP + +P P P+ + P PP + PPP+
Sbjct: 556 PPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEES 615
Query: 467 PPQPGPGPQRQGPPLQQRP--PPQGQQHLSGLGPPAG----SPLP--QRL-PSPTSAPQQ 517
P P P R PP + P PP + S + PP SPLP RL P P +P
Sbjct: 616 PLSPPPEASRLSPPPEDSPMSPPPEE---SPMSPPPEVSRLSPLPVVSRLSPPPEESPLS 672
Query: 518 PASQAAP--PTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPP 575
P + +P P R S P P +PP PASP P+ + P P
Sbjct: 673 PPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEP 732
Query: 576 KASGAPPGGQQRQGP--PQKPPGPAGP--TRQASQAGPVPRTGPP----TTQQPR--PSG 625
+ G P P P P P + QA + P+ P ++P P
Sbjct: 733 QLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQA 792
Query: 626 PGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQA 667
GP P+P+ Q P + P P L P ++
Sbjct: 793 EGPHLSPQPEELHLSPQTEEPHLSPV---PEEPCLSPQPEES 831
Score = 57.4 bits (137), Expect = 4e-08
Identities = 90/327 (27%), Positives = 113/327 (34%), Gaps = 93/327 (28%)
Query: 398 HQDEDKQLIVELVVNKMAQA--LPRQRQRDA-----SPGRGSHGQTPSPGALP---LGRQ 447
H+ Q E +NK + + R+ R A P G+ G +P P A P +G
Sbjct: 2071 HRINKVQKQAESQINKQTKVGDIARKTDRPALHLRIPPQPGALG-SPPPAAAPTIFIGSP 2129
Query: 448 TSQQPAG----------PPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLG 497
T+ PAG PPA P GP PG + P + + P Q L+
Sbjct: 2130 TT--PAGLSTSADGFLKPPAGSVP----GPDSPGELFLKLPPQVPAQVPSQDPFGLAPAY 2183
Query: 498 P-----PAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASP 552
P P P PSPT AP QP G SRP AG PG PP +P
Sbjct: 2184 PLEPRFPTAPPTYPPYPSPTGAPAQPPM--------LGASSRPGAGQPGEFHTT-PPGTP 2234
Query: 553 SPQRQAGPP-QATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQ----- 606
Q P R S+ A P++ G GG + P PP P G +R+A +
Sbjct: 2235 RHQPSTPDPFLKPRCPSLDNLAVPESPGV--GGGKASEPLLSPP-PFGESRKALEVKKEE 2291
Query: 607 -AGPVPRTGPPT-------------------------------TQQPRPSGPGPAGRPKP 634
P GPP Q P PG RP+
Sbjct: 2292 LGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQE 2351
Query: 635 QLAQKPSQDVPPPATAAAGGPP-HPQL 660
PPPA A A PP HP +
Sbjct: 2352 ----------PPPAQALAPSPPSHPDI 2368
Score = 56.2 bits (134), Expect = 9e-08
Identities = 69/291 (23%), Positives = 96/291 (32%), Gaps = 52/291 (17%)
Query: 416 QALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQ 475
Q PR SP +P P L Q +++P P + P P +P PQ
Sbjct: 733 QLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQ-AEEPHLSPQPEEPCLCAVPEEPHLSPQ 791
Query: 476 RQGPPLQQRPPPQGQQHLSG-LGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSR 534
+GP L +P + HLS P SP+P+ P +PQ S +P ++ R
Sbjct: 792 AEGPHLSPQPE---ELHLSPQTEEPHLSPVPEE---PCLSPQPEESHLSPQSEEPCLSPR 845
Query: 535 PVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGP---- 590
P +P +PP SP P++ PP+ Q PAP + PP G+ P
Sbjct: 846 PEESHL-SPELEKPPLSPRPEK---PPEEPGQC----PAPEELPLFPPPGEPSLSPLLGE 897
Query: 591 ------------------PQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRP 632
P P G + Q P+P P P P G
Sbjct: 898 PALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGEL 957
Query: 633 KPQLAQKPSQD--------------VPPPATAAAGGPPHPQLKASPAQAQP 669
+ K D PPP P P + P+ P
Sbjct: 958 EYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSP 1008
Score = 54.7 bits (130), Expect = 3e-07
Identities = 60/236 (25%), Positives = 76/236 (32%), Gaps = 24/236 (10%)
Query: 419 PRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQG 478
P+ + SP +P P L + + P P ++ P G P P P
Sbjct: 826 PQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPP 885
Query: 479 PPLQQRPPPQGQQHLSGLGPPAGSPLPQRLP---------SPTSAPQQP--------ASQ 521
P P G+ LS G P SPLP+ LP SP P P +
Sbjct: 886 PGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITA 945
Query: 522 AAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAP 581
AAPP + G G P A+P + PP T P PP
Sbjct: 946 AAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPE-PVPPMILPPS 1004
Query: 582 PGGQQRQGPP---QKPPGPAGPTRQAS---QAGPVPRTGPPTTQQPRPSGPGPAGR 631
PG P + P P Q S Q P + PP PS P G+
Sbjct: 1005 PGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGK 1060
Score = 51.2 bits (121), Expect = 3e-06
Identities = 79/293 (26%), Positives = 103/293 (35%), Gaps = 54/293 (18%)
Query: 399 QDEDKQLIVELVVNKMAQALP-RQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPP- 456
+ +Q + EL++ + Q RQ + A+ G+ G S GA P Q G
Sbjct: 2679 KQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTP 2738
Query: 457 ---AQQR------PPPQGGPPQPGPGPQRQGPPLQQRPPPQ--GQQHLSGLGPPAGSP-L 504
Q + PP + P GPG L + PPP ++ GS
Sbjct: 2739 FAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAF 2798
Query: 505 PQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQ--RQA-GPP 561
QR P P S P Q Q Q +Q A +AR P++P P+ RQA G P
Sbjct: 2799 YQRAPYPGSLPLQQQQQ-----QLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSP 2853
Query: 562 QATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPT-----RQASQAG------PV 610
A T + GP P PGPAGP R Q G P
Sbjct: 2854 LAGISTRLPGPGEPV------------------PGPAGPAQFIELRHNVQKGLGPGGTPF 2895
Query: 611 PRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKAS 663
P GPP + P P L +PP +A PP P+L S
Sbjct: 2896 PGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSA---PPAPELNNS 2945
Score = 49.3 bits (116), Expect = 1e-05
Identities = 51/145 (35%), Positives = 60/145 (41%), Gaps = 13/145 (8%)
Query: 416 QALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQR----PPPQGGPPQP- 470
QAL QRQ S + QTP P P G QTS Q + P PQ GP Q
Sbjct: 4223 QALLMQRQLQQSQ---AVRQTP-PYQEP-GTQTSPLQGLLGCQPQLGGFPGPQTGPLQEL 4277
Query: 471 GPGPQRQGPPLQQRPPPQGQQHLSG-LGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQ 529
G GP+ QGPP + P P G LGP +P P P Q P+ + PT+ Q
Sbjct: 4278 GAGPRPQGPP--RLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQ 4335
Query: 530 GRQSRPVAGGPGAPPAARPPASPSP 554
+ P P P PP SP
Sbjct: 4336 LPPTHPGTPKPQGPTLEPPPGRVSP 4360
Score = 48.9 bits (115), Expect = 1e-05
Identities = 75/287 (26%), Positives = 91/287 (31%), Gaps = 66/287 (22%)
Query: 428 PGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQ----------RPPPQGGPPQPGPGPQRQ 477
P GS SPG L L + Q PA P+Q P PP P P
Sbjct: 2145 PPAGSVPGPDSPGELFL-KLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPT 2203
Query: 478 GPPLQQRPPPQGQQHLSGLGPPA-------GSPLPQ-RLPSPTSAPQQPA--SQAAP--P 525
G P Q PP G G G P G+P Q P P P+ P+ + A P P
Sbjct: 2204 GAPAQ--PPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESP 2261
Query: 526 TQGQGRQSRPVAGGP-----------------GAPPAARPPA-----SPSPQRQAGPPQA 563
G G+ S P+ P + P+ PP SPS G +
Sbjct: 2262 GVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLEL 2321
Query: 564 TRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRP 623
P P+AS P PQ+PP P P P
Sbjct: 2322 KTPDVFKAPLTPRASQVEPQSPGLGLRPQEPP-------------PAQALAPSPPSHPDI 2368
Query: 624 SGPGPAGRPKPQLAQKPSQDVPPPATAAAGGP------PHPQLKASP 664
PG P Q P PPP + A P P ++ ASP
Sbjct: 2369 FRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASP 2415
Score = 48.9 bits (115), Expect = 1e-05
Identities = 81/287 (28%), Positives = 97/287 (33%), Gaps = 59/287 (20%)
Query: 399 QDEDKQLIVELVVNKMAQALPRQRQRDA-------SPGRGSHGQTPSPGALPLGRQTSQQ 451
Q E L+ E + Q +Q+Q+ SP + T PG L G Q
Sbjct: 3585 QKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGL-QP 3643
Query: 452 PAGPPAQQR------PPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGP---PAGS 502
P GPP Q P P QPG GP QQ Q QQH G G P+G
Sbjct: 3644 PQGPPGGQAGGLRLTPGGMALPGQPG-GPFLNTALAQQ----QQQQHSGGAGSLAGPSGG 3698
Query: 503 PLPQRLPSPTSAP------------QQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPA 550
P L + P QQ Q A Q Q +Q + G
Sbjct: 3699 FFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQ-------V 3751
Query: 551 SPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQ----RQGPPQKPPGPAGPTRQASQ 606
+ Q+Q GP T Q GP P PP Q +Q PQ P GP G A
Sbjct: 3752 AIQQQQQQGPGVQTNQAL--GPKPQGLM--PPSSHQGLLVQQLSPQPPQGPQGMLGPAQV 3807
Query: 607 AGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAG 653
A QQ P GP G P Q+ S+ + P A G
Sbjct: 3808 A---------VLQQQHPGALGPQG-PHRQVLMTQSRVLSSPQLAQQG 3844
Score = 48.5 bits (114), Expect = 2e-05
Identities = 72/251 (28%), Positives = 86/251 (34%), Gaps = 53/251 (21%)
Query: 415 AQALPRQRQRDA-SPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQ-RPPPQGGPPQPGP 472
A PR Q + SPG G Q P PPAQ P P P P
Sbjct: 2329 APLTPRASQVEPQSPGLGLRPQEP-----------------PPAQALAPSPPSHPDIFRP 2371
Query: 473 G----PQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQG 528
G P Q PPL RP P P + LP P S P P S+ Q
Sbjct: 2372 GSYTDPYAQ-PPLTPRPQPP--------PPESCCALP-----PRSLPSDPFSRVPASPQS 2417
Query: 529 QGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQ 588
Q P+ P + A P SP R P +R PP + P +
Sbjct: 2418 QSSSQSPLTPRPLSAEAFCP--SPVTPRFQSPDPYSR--------PP----SRPQSRDPF 2463
Query: 589 GPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQL-AQKPSQDVPPP 647
P KPP P P A +AG + T P GPAG ++ + +P V P
Sbjct: 2464 APLHKPPRPQ-PPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSP 2522
Query: 648 ATAAAGGPPHP 658
T A G P P
Sbjct: 2523 GTGAFVGTPSP 2533
Score = 42.7 bits (99), Expect = 0.001
Identities = 70/274 (25%), Positives = 96/274 (35%), Gaps = 66/274 (24%)
Query: 426 ASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGP--PLQQ 483
ASP S Q+P PL + P Q P P PP PQ + P PL +
Sbjct: 2413 ASPQSQSSSQSPLTPR-PLSAEAFCPSPVTPRFQSPDPYSRPPSR---PQSRDPFAPLHK 2468
Query: 484 RPPPQGQQ-----------HLSGLGPPAGSP------LPQRLPS--PTSAPQQPASQAAP 524
P PQ + L G PA P L ++PS P + + P + A
Sbjct: 2469 PPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFV 2528
Query: 525 PTQGQGRQSRPVAGG----------PGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAP 574
T R + P A G PG PP + P G PQ+T T +G
Sbjct: 2529 GTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFH 2588
Query: 575 PKASGAPPG----------GQQRQGPPQKPPGPA----------GPTRQASQAGPVPRTG 614
P SG+P G G PP P PA G ++++ PV +
Sbjct: 2589 P--SGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKRE 2646
Query: 615 PP---------TTQQPRPSGPGPAGRPKPQLAQK 639
P T + P PG +G + +L ++
Sbjct: 2647 DPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQ 2680
Score = 37.4 bits (85), Expect = 0.045
Identities = 63/245 (25%), Positives = 80/245 (32%), Gaps = 23/245 (9%)
Query: 432 SHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQ 491
SH P A P+G Q QQ+ Q Q Q Q LQQ+ Q QQ
Sbjct: 3882 SHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQ---QQQQ 3938
Query: 492 HLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQ------------GQGRQSRPVAGG 539
L Q+L QQ Q Q Q +Q + VA G
Sbjct: 3939 QLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALG 3998
Query: 540 PGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAG 599
PG P A+P S GP + P +S A G QG P
Sbjct: 3999 PGMP--AKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAI--GTT 4054
Query: 600 PTRQASQAGPVPRTGPPTTQ----QPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGP 655
P A++ G V + +Q QP+P + + +P L Q AGG
Sbjct: 4055 PESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGG 4114
Query: 656 PHPQL 660
H QL
Sbjct: 4115 SHGQL 4119
Score = 37.0 bits (84), Expect = 0.059
Identities = 30/86 (34%), Positives = 38/86 (44%), Gaps = 14/86 (16%)
Query: 450 QQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLP 509
Q A PP + PPP P P P P ++ P + PP SPLP
Sbjct: 4905 QLSAPPPEEPSPPPS--PLAPSPASPPTEPLVELPTEPLAE-------PPVPSPLP-LAS 4954
Query: 510 SPTSAPQQPASQAAPPTQGQGRQSRP 535
SP SA +P +A PP +G+ SRP
Sbjct: 4955 SPESA--RPKPRARPPEEGE--DSRP 4976
Score = 35.0 bits (79), Expect = 0.22
Identities = 40/135 (29%), Positives = 51/135 (37%), Gaps = 15/135 (11%)
Query: 513 SAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGP 572
SA QPA Q Q Q +Q + PG A P S AG Q Q S+
Sbjct: 3267 SAQLQPAQQ-----QQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQ---QLSLG-- 3316
Query: 573 APPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTT-QQPRPSGPGPAGR 631
+GA G + P +PP A R A V G + Q +G P
Sbjct: 3317 ----LAGARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQS 3372
Query: 632 PKPQLAQKPSQDVPP 646
+P L+QKP +PP
Sbjct: 3373 SQPVLSQKPMGTMPP 3387
Score = 34.3 bits (77), Expect = 0.38
Identities = 56/201 (27%), Positives = 81/201 (40%), Gaps = 32/201 (15%)
Query: 401 EDKQLIVELVVNKMAQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQR 460
+++QL ++ ++AQ L +Q+Q+ Q G + + +Q Q GP Q
Sbjct: 3717 QERQLQLQQQRMQLAQKLQQQQQQQQQ-------QQHLLGQVAIQQQQQQ---GPGVQTN 3766
Query: 461 ----PPPQGGPPQPGPGPQRQGPPLQQ--RPPPQGQQHLSGLGPPAGSPLPQRLPSPTSA 514
P PQG P QG +QQ PPQG Q + LGP + L Q+ P
Sbjct: 3767 QALGPKPQGLMPP----SSHQGLLVQQLSPQPPQGPQGM--LGPAQVAVLQQQHPG-ALG 3819
Query: 515 PQQPASQAAPPTQGQGRQSRPVA-GGPGAPPAARPPASPSPQRQAGPPQAT-------RQ 566
PQ P Q TQ + S +A G G A Q+Q Q + +Q
Sbjct: 3820 PQGPHRQVL-MTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQ 3878
Query: 567 TSVSGPAPPKASGAPPGGQQR 587
+ +S PK S P G Q+
Sbjct: 3879 SLMSHSGQPKLSAQPMGSLQQ 3899
Score = 33.9 bits (76), Expect = 0.50
Identities = 85/344 (24%), Positives = 109/344 (31%), Gaps = 92/344 (26%)
Query: 410 VVNKMAQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPA-----QQRPPPQ 464
++N+ L Q+Q+ G P A PL +S GP +Q
Sbjct: 3977 LLNQSRTLLSPQQQQQQQVALG-----PGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDP 4031
Query: 465 GGPPQPGPGPQ-RQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRL-PSPTSAPQQPASQA 522
+ GP QG PL P+ G P+ S Q L P PQ + Q
Sbjct: 4032 AVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQL 4091
Query: 523 APPTQGQGRQSRPVA-------------GGPGAPPAARPP---ASPS----------PQR 556
PP + G+Q + V+ G + A+ P A PS Q
Sbjct: 4092 QPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQN 4151
Query: 557 QAGPPQATRQTSV---SGPAPPKASGAPPGGQ----------------QRQGPPQKPP-- 595
GP Q + + +GP PPK GQ Q QG K P
Sbjct: 4152 LLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQL 4211
Query: 596 ---GPAGP--------TRQASQAGPVPRTGP---PTTQ----------QPRPSG-PGPAG 630
P RQ Q+ V +T P P TQ QP+ G PGP
Sbjct: 4212 RHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQT 4271
Query: 631 RPKPQLAQKPSQDVPPPATAAAG--------GPPHPQLKASPAQ 666
P +L P PP A G GP HP S Q
Sbjct: 4272 GPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQ 4315
Score = 33.9 bits (76), Expect = 0.50
Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 5/61 (8%)
Query: 435 QTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGP-----GPQRQGPPLQQRPPPQG 489
+ PSP PL + P P + P PP P P P+ P + RPP +G
Sbjct: 4912 EEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEG 4971
Query: 490 Q 490
+
Sbjct: 4972 E 4972
Score = 33.1 bits (74), Expect = 0.85
Identities = 21/47 (44%), Positives = 21/47 (44%), Gaps = 3/47 (6%)
Query: 27 RPQPPP---PPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGS 70
RPQ PP PPGA S G GP T SS P PSP S
Sbjct: 4282 RPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSS 4328
Score = 32.7 bits (73), Expect = 1.1
Identities = 30/109 (27%), Positives = 39/109 (35%), Gaps = 17/109 (15%)
Query: 551 SPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKP--PGPAGPTRQASQAG 608
SP+P+ P Q + +VS + S PP + PP P P PA P +
Sbjct: 4883 SPAPEP---PTQHSYTYNVSNLDVRQLSAPPP---EEPSPPPSPLAPSPASPPTEPLVEL 4936
Query: 609 PVPRTGPPTTQQPRPSGPGP-AGRPKPQLAQKPSQDVPPPATAAAGGPP 656
P P P P P + RPKP+ PP PP
Sbjct: 4937 PTEPLAEPPVPSPLPLASSPESARPKPRAR--------PPEEGEDSRPP 4977
Score = 32.3 bits (72), Expect = 1.5
Identities = 44/189 (23%), Positives = 70/189 (37%), Gaps = 31/189 (16%)
Query: 491 QHLSGLGPPAGSPLPQRLPSPTSA--PQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARP 548
++L+G+ L ++P+ P+ PA P +G+ A GPG
Sbjct: 4794 KNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGE-------AEGPGGKEKGLE 4846
Query: 549 PASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPT------- 601
SP GP + +V K+ +++ P +PP T
Sbjct: 4847 GKSPD----TGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLD 4902
Query: 602 -RQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQL 660
RQ S P + PP+ P P+ P P +L +P + P P+ P P L
Sbjct: 4903 VRQLSAPPPEEPSPPPSPLAPSPAS--PPTEPLVELPTEPLAEPPVPS-------PLP-L 4952
Query: 661 KASPAQAQP 669
+SP A+P
Sbjct: 4953 ASSPESARP 4961
Score = 31.2 bits (69), Expect = 3.2
Identities = 21/51 (41%), Positives = 26/51 (50%), Gaps = 6/51 (11%)
Query: 28 PQPP-PPPPGAHS---PGATPGPGTAT--AERSSGVAPAASPAAPSPGSSG 72
PQP PPP G +S PG T G +T + P+ SP PS GS+G
Sbjct: 2552 PQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTG 2602
Score = 30.8 bits (68), Expect = 4.2
Identities = 43/165 (26%), Positives = 54/165 (32%), Gaps = 43/165 (26%)
Query: 480 PLQQRPPPQGQQH--LSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVA 537
P QQ+ Q QQH LS GP LP SP+ A Q + S +A
Sbjct: 3272 PAQQQQQQQ-QQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQ------------QLSLGLA 3318
Query: 538 GGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGP 597
G AR P P P PP Q ++ P + G G
Sbjct: 3319 G-------ARQPGLPQPLMPTQPPAHALQQRLA----PSMAMVSNQGHMLSG-------- 3359
Query: 598 AGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQ 642
+ QAG VP+ +P G P P + KP Q
Sbjct: 3360 ----QHGGQAGLVPQQSSQPVLSQKPMGTMP-----PSMCMKPQQ 3395
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 85.9 bits (211), Expect = 1e-16
Identities = 81/265 (30%), Positives = 94/265 (35%), Gaps = 36/265 (13%)
Query: 424 RDASPG-RGSHGQTPSPGAL-PLGRQTSQQPAGPPAQQRPPPQGGP-------------- 467
+D PG G+ G SPG P G G P Q PP GP
Sbjct: 901 KDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAG 960
Query: 468 PQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQ 527
P PGP R P Q G+ +GL G P PQ LP +P P +
Sbjct: 961 PPGMPGP-RGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSD 1019
Query: 528 GQ--------GRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASG 579
G G+ R G PGAP A P P P GP + SGPA P +
Sbjct: 1020 GLPGRDGSPGGKGDRGENGSPGAPGA---PGHPGPPGPVGPAGKSGDRGESGPAGPAGAP 1076
Query: 580 APPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGR------PK 633
P G + G PQ P G G T + AG G P P PGPAG+ P
Sbjct: 1077 GPAGSRGAPG-PQGPRGDKGETGERGAAGIKGHRGFP-GNPGAPGSPGPAGQQGAIGSPG 1134
Query: 634 PQLAQKPSQDVPPPATAAAGGPPHP 658
P + P PP G P P
Sbjct: 1135 PAGPRGPVGPSGPPGKDGTSGHPGP 1159
Score = 83.2 bits (204), Expect = 7e-16
Identities = 85/276 (30%), Positives = 105/276 (38%), Gaps = 55/276 (19%)
Query: 425 DASPGR-GSHGQTPSPGALPLGRQTSQQPA--GPPAQQRPPPQ---GGPPQPGPGPQRQG 478
+ PG G G +PGA P G+ + P GPP P GPP P G G
Sbjct: 653 NGKPGEPGPKGDAGAPGA-PGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAG 711
Query: 479 PP----------LQQRPPPQGQQHLSGLGPPA--------GSPLPQRLPSPTSAPQQPAS 520
PP LQ P +G GLG P G P +P P+ P
Sbjct: 712 PPGPPGAAGTPGLQGMPGERG-----GLGSPGPKGDKGEPGGPGADGVPGK-DGPRGPTG 765
Query: 521 QAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGA 580
PP + G PG P A P SP + + GPP P P +G
Sbjct: 766 PIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPA-----GFPGAPGQNGE 820
Query: 581 PPGGQQRQGPPQK----PPGPAGPTRQASQAGPVPRTGPPTTQQPR--PSGPGPAGRPKP 634
P G +R P +K PPG AGP + AGP GP + R P GPG AG P
Sbjct: 821 PGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGP---PGPQGVKGERGSPGGPGAAGFP-- 875
Query: 635 QLAQKPSQDVP-PPATAAAGGPPHPQLKASPAQAQP 669
++ +P PP + GPP P SP + P
Sbjct: 876 -----GARGLPGPPGSNGNPGPPGP--SGSPGKDGP 904
Score = 80.9 bits (198), Expect = 4e-15
Identities = 81/280 (28%), Positives = 97/280 (34%), Gaps = 42/280 (15%)
Query: 416 QALPRQRQRDASPG-RGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGP 474
Q +P +R SPG +G G+ PGA G P GP PP G QPG
Sbjct: 725 QGMPGERGGLGSPGPKGDKGEPGGPGAD--GVPGKDGPRGPTGPIGPPGPAG--QPGDKG 780
Query: 475 QRQGPPLQQRPPPQGQQHLSG-LGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQS 533
+ P L P+G G GPP + P P P + AP +G+G
Sbjct: 781 EGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGA-PGQNGEPGGKGERGAPGEKGEGGPP 839
Query: 534 RPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSG-------------PAPPKASGA 580
VAG PG A PP + + G P G P PP SG+
Sbjct: 840 G-VAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGS 898
Query: 581 P-----PGGQQRQGPPQKP--PGPAGPTRQASQAGPVPRTGPPTTQQPR----------- 622
P PG G P P GP G Q + G GPP P
Sbjct: 899 PGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGL 958
Query: 623 ---PSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQ 659
P PGP G P PQ + S + GPP PQ
Sbjct: 959 AGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQ 998
Score = 79.7 bits (195), Expect = 8e-15
Identities = 96/328 (29%), Positives = 111/328 (33%), Gaps = 90/328 (27%)
Query: 419 PRQRQRDASPGR-GSHGQTPSPGAL-PLGRQTSQQPAGPPAQQR----PPPQGGPPQPGP 472
P R SPG GS G+ PG+ GR P+GP Q P P+G PG
Sbjct: 533 PGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGK 592
Query: 473 GPQRQGP--PLQQRPP-------PQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAA 523
+R GP P Q PP PQG +G G G P P P P +
Sbjct: 593 NGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGP---PGPQGLQGLPGTGGP 649
Query: 524 PPTQGQGRQSRPV--AGGPGAP--------PAARPP----ASPSPQRQAGPPQATRQTSV 569
P G+ + P AG PGAP P R P +P + AGPP
Sbjct: 650 PGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGA 709
Query: 570 SG-PAPPKASGAP-----------------------PGGQQRQGPPQK-----PPGPAGP 600
+G P PP A+G P PGG G P K P GP GP
Sbjct: 710 AGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGP 769
Query: 601 TRQASQAGPV-------------PR--------TGPP--------TTQQPRPSGPGPAGR 631
A Q G PR TGPP Q P G G G
Sbjct: 770 PGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGA 829
Query: 632 PKPQLAQKPSQDVPPPATAAAGGPPHPQ 659
P + P PP + GPP PQ
Sbjct: 830 PGEKGEGGPPGVAGPPGGSGPAGPPGPQ 857
Score = 78.6 bits (192), Expect = 2e-14
Identities = 82/297 (27%), Positives = 99/297 (33%), Gaps = 61/297 (20%)
Query: 419 PRQRQRDASPGR----GSHGQTPSPGAL-PLGRQTSQQPAGPPAQQRPPPQGGPPQPGPG 473
P +R PG G+ GQ PG G + GPP PP GP P PG
Sbjct: 797 PGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGP-PG 855
Query: 474 PQ----RQGPP----------LQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPA 519
PQ +G P + P P G G P+GSP P P P
Sbjct: 856 PQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPG 915
Query: 520 SQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASG 579
S +G Q G G+P A PP +P P AG A G P+ S
Sbjct: 916 SPGVSGPKGDAGQP----GEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSP 971
Query: 580 APPGGQQRQGPP--------QKPPGPAGPTRQASQAGPVPRTGPPTTQ------------ 619
P G + G P + PPGP G A AG R G P +
Sbjct: 972 GPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGK 1031
Query: 620 ----------------QPRPSGP-GPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQ 659
P P GP GPAG+ + P+ P A + G P PQ
Sbjct: 1032 GDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQ 1088
Score = 75.1 bits (183), Expect = 2e-13
Identities = 86/284 (30%), Positives = 101/284 (35%), Gaps = 59/284 (20%)
Query: 419 PRQRQRDASPG----------RGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPP 468
P +R R PG RGS GQ PG P G T+ P P A+ P G P
Sbjct: 305 PGERGRPGLPGAAGARGNDGARGSDGQPGPPG--PPG--TAGFPGSPGAKGEVGPAGSPG 360
Query: 469 QPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPA-----GSPLPQRLPSPTSAPQQPASQAA 523
G QR P PQG H GPP GSP + P P P A
Sbjct: 361 SNGAPGQRG------EPGPQG--HAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGA 412
Query: 524 --PPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGP------PQATRQTSVSG-PAP 574
PP + + GG G P P P+ + G P A + G P
Sbjct: 413 RGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGE 472
Query: 575 PKASGAPPGGQQRQGP----PQKP---------------PGPAGPTRQASQAG--PVPRT 613
P A+G P +R P P P PGPAGP A + G VP
Sbjct: 473 PGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVP-G 531
Query: 614 GPPTTQQP-RPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPP 656
GP P P GPG G+P P +Q S PP + G P
Sbjct: 532 GPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQP 575
Score = 75.1 bits (183), Expect = 2e-13
Identities = 92/331 (27%), Positives = 114/331 (34%), Gaps = 91/331 (27%)
Query: 415 AQALPRQRQRDASPG-RGSHGQTPSPGALPLGRQTSQQPAGPP-AQQRPPPQGGPPQPG- 471
AQ P + SPG +G G PGA G ++ P GP A P +GG +PG
Sbjct: 379 AQGPPGPPGINGSPGGKGEMGPAGIPGAP--GLMGARGPPGPAGANGAPGLRGGAGEPGK 436
Query: 472 ------PGPQRQG-----------------------PPLQQRPPPQGQQHLSGLGPPAGS 502
PGP+ + P P G++ G PAG
Sbjct: 437 NGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAG- 495
Query: 503 PLPQRLPSPTS-APQQPASQAAPPTQGQGRQSRP-VAGGPGAPPAARPPASPSPQRQAGP 560
P +P A ++ A A P G R V GGPG P P + GP
Sbjct: 496 --PNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGP 553
Query: 561 PQATRQTSVSGPAPPKA----------------SGAP--------PGGQQRQGP------ 590
P + ++ GP P GAP PGG QGP
Sbjct: 554 PGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGE 613
Query: 591 --PQKPPGPAGPTRQASQAGP--------VPRTGPPTTQQPRPSGPGP---AGRPKPQ-- 635
PQ PPGP GP GP +P TG P + +P PGP AG P
Sbjct: 614 TGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGG 673
Query: 636 --LAQKPSQDVPPPATAAAG-----GPPHPQ 659
A P + PP A G GPP P+
Sbjct: 674 KGDAGAPGERGPPGLAGAPGLRGGAGPPGPE 704
Score = 63.5 bits (153), Expect = 6e-10
Identities = 72/270 (26%), Positives = 93/270 (34%), Gaps = 42/270 (15%)
Query: 435 QTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPP----QPGPGPQRQGPPLQQRPPPQGQ 490
Q P+ P Q Q P G P P + G P QPG P GPP P G
Sbjct: 90 QPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPG-SPGSPGPPGICESCPTGP 148
Query: 491 QH------------------LSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQ 532
Q+ L+G PAG P P P + P P S G+ Q
Sbjct: 149 QNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQ 208
Query: 533 SRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPG--------- 583
+ P +G PG P A P ++G P + + GP K PG
Sbjct: 209 AGP-SGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRG 267
Query: 584 -----GQQRQGPPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAG-RPKPQLA 637
G++ + G G + GP+ G P ++ RP PG AG R
Sbjct: 268 FDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAP-GERGRPGLPGAAGARGNDGAR 326
Query: 638 QKPSQDVP--PPATAAAGGPPHPQLKASPA 665
Q P PP TA G P + + PA
Sbjct: 327 GSDGQPGPPGPPGTAGFPGSPGAKGEVGPA 356
Score = 62.8 bits (151), Expect = 1e-09
Identities = 67/225 (29%), Positives = 78/225 (34%), Gaps = 33/225 (14%)
Query: 416 QALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPG-PGP 474
Q LP PGR + P LP GR S G + P G P PG PGP
Sbjct: 998 QGLPGLAGTAGEPGRDGN---PGSDGLP-GRDGSPGGKGDRGENGSP--GAPGAPGHPGP 1051
Query: 475 QRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQG--RQ 532
P P G SG +G P P P + P Q +G+ R
Sbjct: 1052 ----------PGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERG 1101
Query: 533 SRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPK---ASGAPPGGQQRQG 589
+ + G G P P SP P Q G GPA P+ PPG G
Sbjct: 1102 AAGIKGHRGFPGNPGAPGSPGPAGQQGA------IGSPGPAGPRGPVGPSGPPGKDGTSG 1155
Query: 590 PPQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKP 634
P P GP GP + G G P +P PGP G P P
Sbjct: 1156 HP-GPIGPPGPRGNRGERGSEGSPGHP----GQPGPPGPPGAPGP 1195
Score = 58.2 bits (139), Expect = 2e-08
Identities = 64/208 (30%), Positives = 75/208 (36%), Gaps = 37/208 (17%)
Query: 437 PSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGL 496
P+P +P G + P P A RPP GP P P GPP P G + G
Sbjct: 75 PNP-EIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDP---GPP--GIPGRNGDPGIPGQ 128
Query: 497 GPPAGSPLPQRL--PSPTS----APQQPASQAAPPTQGQGRQSRPVAGGPGAPPA----A 546
GSP P + PT +PQ + G P GP PP +
Sbjct: 129 PGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTS 188
Query: 547 RPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQ 606
P SP GPP Q SG PPG PPG GP+ A +
Sbjct: 189 GHPGSPGSPGYQGPPGEPGQAGPSG---------PPG----------PPGAIGPSGPAGK 229
Query: 607 AGPVPRTGPPTTQ-QPRPSG-PGPAGRP 632
G R G P + P P G GPAG P
Sbjct: 230 DGESGRPGRPGERGLPGPPGIKGPAGIP 257
Score = 56.6 bits (135), Expect = 7e-08
Identities = 80/314 (25%), Positives = 97/314 (30%), Gaps = 77/314 (24%)
Query: 428 PGRGSHGQTP-SPGAL-PLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRP 485
PG H +P SPG P G P+GPP PP GP P G P RP
Sbjct: 185 PGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPG---PPGAIGPSGPAGKDGESGRP--GRP 239
Query: 486 PPQGQQHLSGLGPPAGSP-LP--------------------------QRLPSPTSAPQQP 518
+G G+ PAG P P LP AP
Sbjct: 240 GERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPM 299
Query: 519 ASQAAPPTQGQ--------------GRQSRPVAGGPGAPPAARPPASPSPQRQAGP---- 560
+ AP +G+ R S G PG P A P SP + + GP
Sbjct: 300 GPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSP 359
Query: 561 -----------PQATRQTSVSGPAPPKASGAPPGGQQRQGP-----------PQKPPGPA 598
P GP P PGG+ GP + PPGPA
Sbjct: 360 GSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPA 419
Query: 599 GPTRQASQAGPVPRTGPPTTQ-QPRPSGP-GPAGRP-KPQLAQKPSQDVPPPATAAAGGP 655
G G G + +P P G G AG P P + +D P A G P
Sbjct: 420 GANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLP 479
Query: 656 PHPQLKASPAQAQP 669
+ +P P
Sbjct: 480 GAAGERGAPGFRGP 493
Score = 33.1 bits (74), Expect = 0.85
Identities = 29/87 (33%), Positives = 33/87 (37%), Gaps = 10/87 (11%)
Query: 34 PPGAHSPGATPGPGTATAERSSGVAPAAS--PAAPS----PGSSGGGGFFSSLSNAVKQT 87
PPG P PGP ER S P A+ P A PGS+G G + K
Sbjct: 844 PPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDG 903
Query: 88 TAAAA----ATFSEQVGGGSGGAGRGG 110
A A S V G G AG+ G
Sbjct: 904 PPGPAGNTGAPGSPGVSGPKGDAGQPG 930
Score = 32.3 bits (72), Expect = 1.5
Identities = 31/110 (28%), Positives = 40/110 (36%), Gaps = 26/110 (23%)
Query: 27 RPQPPPPP--------PGAH-------SPGATPGPGTATAERSSGVAPAASPAAPSPGSS 71
+P PP PP PGA SPG+ PG G A A P P PG +
Sbjct: 331 QPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGP-PGIN 389
Query: 72 GGGGFFSSLSNA----------VKQTTAAAAATFSEQVGGGSGGAGRGGA 111
G G + A + A A + + GG+G G+ GA
Sbjct: 390 GSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGA 439
Score = 32.0 bits (71), Expect = 1.9
Identities = 19/56 (33%), Positives = 23/56 (41%), Gaps = 1/56 (1%)
Query: 20 GYMTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGG 75
GY P PP PP + PG+ PG G A + P P PG+ G G
Sbjct: 171 GYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGP-PGAIGPSG 225
Score = 30.4 bits (67), Expect = 5.5
Identities = 20/54 (37%), Positives = 22/54 (40%), Gaps = 5/54 (9%)
Query: 27 RPQPPPPPPGAHSPGATPGPGTATAERSSGV-----APAASPAAPSPGSSGGGG 75
+P P P A +PGA G G A A G AP A PG GG G
Sbjct: 655 KPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKG 708
>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
Length = 680
Score = 85.5 bits (210), Expect = 1e-16
Identities = 82/247 (33%), Positives = 93/247 (37%), Gaps = 25/247 (10%)
Query: 430 RGSHGQTPSPG-ALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGP-GPQRQGPP----LQQ 483
RG G PG A P G P G P P QG P PGP GP G P L
Sbjct: 56 RGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPG 115
Query: 484 RPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGP-GA 542
+P +G G PAG P P+ P P P PA + P GQ Q A GP G
Sbjct: 116 KPGERGPYGPKGDVGPAGLPGPRGPPGPPGIP-GPAGISVPGKPGQ--QGPTGAPGPRGF 172
Query: 543 PPAARPPASPSPQRQA-----GPPQATRQTSVSGPAPPKASGAPPG-GQQRQGPPQKPPG 596
P P P Q G P + + GP P PPG G++ + PG
Sbjct: 173 PGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPG 232
Query: 597 PAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPP-----PATAA 651
G + GP+ GPP Q P P GP G KP A P Q P P
Sbjct: 233 IKGDRGFPGEMGPI---GPPGPQGP-PGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPG 288
Query: 652 AGGPPHP 658
GPP P
Sbjct: 289 IAGPPGP 295
Score = 80.1 bits (196), Expect = 6e-15
Identities = 87/279 (31%), Positives = 104/279 (37%), Gaps = 47/279 (16%)
Query: 413 KMAQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPG- 471
K A +P + G G+ G+ P LP G Q P+GPP + G P QPG
Sbjct: 176 KGAPGVPGMNGQKGEMGYGAPGR-PGERGLP-GPQGPTGPSGPPGVGKRGENGVPGQPGI 233
Query: 472 ------PGPQRQ-GPPLQQRPPPQGQQHLSGLGPP--AGSPLPQRLPSPTSAPQQPASQA 522
PG GPP Q PP G++ G+G P AG+P +P P P
Sbjct: 234 KGDRGFPGEMGPIGPPGPQGPP--GERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAG 291
Query: 523 APPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPP 582
P G G+ P G P A P P + + GP P P +G PP
Sbjct: 292 PPGPPGFGKPGLPGLKGERGP--AGLPGGPGAKGEQGPAGL--------PGKPGLTG-PP 340
Query: 583 GGQQRQGPPQKP-----PGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLA 637
G QGP P PGP G T GP G P + R S PG G KP
Sbjct: 341 GNMGPQGPKGIPGSHGLPGPKGET------GPAGPAGYPGAKGERGS-PGSDG--KPGYP 391
Query: 638 QKPSQDVP--------PPATAAAGGPPHPQLKASPAQAQ 668
KP D P P GGPP PA A+
Sbjct: 392 GKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAK 430
Score = 78.2 bits (191), Expect = 2e-14
Identities = 82/265 (30%), Positives = 99/265 (37%), Gaps = 47/265 (17%)
Query: 428 PGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPP- 486
PG G+ PG L R + P GP A+ P G P +PG GPP P
Sbjct: 293 PGPPGFGKPGLPG-LKGERGPAGLPGGPGAKGEQGPAGLPGKPG----LTGPPGNMGPQG 347
Query: 487 PQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQ-GRQSRPVAGGP----- 540
P+G GL P G P P P + +P + G+ G +P GP
Sbjct: 348 PKGIPGSHGLPGPKGETGPA---GPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPG 404
Query: 541 -----GAPPAARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKP- 594
G P PP P P GP A +G A P+ + PG + GPP P
Sbjct: 405 LPGPKGDPGVGGPPGLPGP---VGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPG 461
Query: 595 ----------PGPAGPTRQASQAGPVPRTGPPTTQQPR-----PSGPGPAGRPKPQLAQK 639
PGP GP A++ P TGPP PR P PGP G P P
Sbjct: 462 FPGSKGDPGSPGPPGPAGIATKGLNGP-TGPPGPPGPRGHSGEPGLPGPPGPPGP----- 515
Query: 640 PSQDVPPPATAAAGGPPHPQLKASP 664
P Q V P AG P L +P
Sbjct: 516 PGQAVMPEGFIKAG--QRPSLSGTP 538
Score = 72.8 bits (177), Expect = 1e-12
Identities = 76/246 (30%), Positives = 88/246 (35%), Gaps = 23/246 (9%)
Query: 428 PGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPP 487
PG + G+ PG LP G+ + P GP P GP P P GP P
Sbjct: 100 PGPSAVGKPGVPG-LP-GKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGK 157
Query: 488 QGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAAR 547
GQQ P G+P P+ P AP P G G RP G P +
Sbjct: 158 PGQQG------PTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRP---GERGLPGPQ 208
Query: 548 PPASPSPQRQAGPPQATRQTSVSGPAPP--KASGAPPGGQQRQGP--PQKPPGPAGP--T 601
P PS GPP ++ P P K PG GP PQ PPG GP
Sbjct: 209 GPTGPS-----GPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGI 263
Query: 602 RQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLK 661
+ AG + G P T + P PG AG P P KP AG P P K
Sbjct: 264 GKPGAAGAPGQPGIPGT-KGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAK 322
Query: 662 ASPAQA 667
A
Sbjct: 323 GEQGPA 328
Score = 50.1 bits (118), Expect = 7e-06
Identities = 48/166 (28%), Positives = 59/166 (35%), Gaps = 27/166 (16%)
Query: 527 QGQGRQSRPVAGGPGAPPAARP-----PASPSPQRQAGPPQATRQTSVSGPAPPKASGAP 581
+ +G R G PG P A P P+ P + G P + + GP P A G P
Sbjct: 49 KSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKP 108
Query: 582 -----PGGQQRQGP--------PQKPPGPAGPTRQASQAGPVPRTGPPTTQQPRPSG-PG 627
PG +GP P PGP GP GP + P Q P+G PG
Sbjct: 109 GVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPG 168
Query: 628 PAGRPKPQLA--------QKPSQDVPPPATAAAGGPPHPQLKASPA 665
P G P + A QK P G P PQ P+
Sbjct: 169 PRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPS 214
Score = 38.5 bits (88), Expect = 0.020
Identities = 34/114 (29%), Positives = 41/114 (35%), Gaps = 31/114 (27%)
Query: 567 TSVSGPAPP-----------KASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGP 615
T + GP P K+ G G+Q G P PPGPAGP +GP
Sbjct: 29 TGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQ--GTPG-PPGPAGPRGHPGPSGP------ 79
Query: 616 PTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQP 669
PG G P L +P PP +A G P P L P + P
Sbjct: 80 ----------PGKPGYGSPGLQGEPGLP-GPPGPSAVGKPGVPGLPGKPGERGP 122
Score = 30.4 bits (67), Expect = 5.5
Identities = 18/49 (36%), Positives = 20/49 (40%), Gaps = 3/49 (6%)
Query: 28 PQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGGF 76
PQ P PG+H PGP T P A SPGS G G+
Sbjct: 345 PQGPKGIPGSHG---LPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGY 390
>gi|192807323 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform A [Homo sapiens]
Length = 1679
Score = 85.1 bits (209), Expect = 2e-16
Identities = 80/248 (32%), Positives = 91/248 (36%), Gaps = 40/248 (16%)
Query: 429 GRGSHGQTPSPGALPL-GRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPP 487
G H +P P + P G Q S P G P P G GP P Q Q R
Sbjct: 125 GGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQI 184
Query: 488 QGQQHLSGLGPPAGSPLPQRLPSPTSAPQ-QPASQAAPPTQGQGRQSRPVAGGPGAPPAA 546
+ L+ G PLP L + P Q PT S A GPG P
Sbjct: 185 MAYKMLA-----RGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVS---ATGPGPGPGP 236
Query: 547 RPPASPSPQRQAGPPQATRQTSVSGP--APPKASGAPPG--GQQRQGPPQKPPGPAGPTR 602
P P P PP +R + GP PP SG PPG GQ GPP+ P P GP
Sbjct: 237 GPGPGPGP----APPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPK--PWPEGPMA 290
Query: 603 QASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKA 662
A+ PT+ + P P GRP P PPA A P P
Sbjct: 291 NAA---------APTSTPQKLIPPQPTGRPSP----------APPAVPPAASPVMPPQTQ 331
Query: 663 SPAQ-AQP 669
SP Q AQP
Sbjct: 332 SPGQPAQP 339
Score = 60.5 bits (145), Expect = 5e-09
Identities = 68/211 (32%), Positives = 83/211 (39%), Gaps = 35/211 (16%)
Query: 398 HQDEDKQLIVELVVNKM---AQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAG 454
+Q++ QL +++ KM Q LP Q G+ P PG Q P
Sbjct: 173 NQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQ------GKRPMPG------MQQQMPTL 220
Query: 455 PP---AQQRPPPQGGP-PQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSP-LPQRLP 509
PP + P P GP P PGPGP PP RP G ++ GP P +P + P
Sbjct: 221 PPPSVSATGPGPGPGPGPGPGPGP---APPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPP 277
Query: 510 S--PTSAPQQPASQAAPPTQGQGRQSRPVAGG--PGAPPAARPPASPSPQRQAGPPQATR 565
P P+ P + AA PT + P G APPA P ASP PPQ
Sbjct: 278 GGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASP-----VMPPQT-- 330
Query: 566 QTSVSGPAPPKASGAPPGGQQRQGPPQKPPG 596
S PA P Q R P QKP G
Sbjct: 331 -QSPGQPAQPAPMVPLHQKQSRITPIQKPRG 360
Score = 58.5 bits (140), Expect = 2e-08
Identities = 72/247 (29%), Positives = 86/247 (34%), Gaps = 44/247 (17%)
Query: 462 PPQGGPPQPGPGP---QRQGPPLQQRPPPQGQQHLSGLG-----PPAGSPLPQRLPSPTS 513
PP GG P+PGP P G L P P S +G P AG P+P + P
Sbjct: 6 PPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQ--GPGG 63
Query: 514 APQQPASQAAPPTQG----------QGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQA 563
PQ Q P + + Q + + G PP SP Q G P
Sbjct: 64 YPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSP 123
Query: 564 TRQTS-VSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQ-AGPVPRTGPPTTQ-- 619
+ S P P ASG G Q GP P A P Q GP P Q
Sbjct: 124 LGGSEHASSPVP--ASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLR 181
Query: 620 ------------QPRPSGPGPA---GRPKPQLAQKPSQDVPPPATAAAG-GP-PHPQLKA 662
QP P A RP P + Q+ +PPP+ +A G GP P P
Sbjct: 182 AQIMAYKMLARGQPLPDHLQMAVQGKRPMPGM-QQQMPTLPPPSVSATGPGPGPGPGPGP 240
Query: 663 SPAQAQP 669
P A P
Sbjct: 241 GPGPAPP 247
Score = 34.3 bits (77), Expect = 0.38
Identities = 33/124 (26%), Positives = 46/124 (37%), Gaps = 24/124 (19%)
Query: 569 VSGPAPPKASGAPPGGQQRQGP-PQKPPGPA-GPTRQASQAGPVPRTGPPTTQQPRPSGP 626
+S P PP PG GP P GP+ GP+ ++ + P GPP+ P P+
Sbjct: 1 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPT-Q 59
Query: 627 GPAGRPKPQLAQ--KPSQDVPPPAT-------------------AAAGGPPHPQLKASPA 665
GP G P+ + Q KP + + A G PP P + S
Sbjct: 60 GPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQG 119
Query: 666 QAQP 669
P
Sbjct: 120 YPSP 123
Score = 33.1 bits (74), Expect = 0.85
Identities = 19/51 (37%), Positives = 23/51 (45%), Gaps = 7/51 (13%)
Query: 30 PPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAA------PSPGSSGGG 74
P PP G PG +PGPG + G +P SP + PSPG G
Sbjct: 4 PDPPLGGTPRPGPSPGPGPSPG-AMLGPSPGPSPGSAHSMMGPSPGPPSAG 53
Score = 33.1 bits (74), Expect = 0.85
Identities = 19/53 (35%), Positives = 24/53 (45%), Gaps = 4/53 (7%)
Query: 28 PQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPG----SSGGGGF 76
P+P P P SPGA GP + S+ SP PS G + G GG+
Sbjct: 12 PRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGY 64
Score = 33.1 bits (74), Expect = 0.85
Identities = 19/58 (32%), Positives = 22/58 (37%), Gaps = 7/58 (12%)
Query: 22 MTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAAS-------PAAPSPGSSG 72
M +Q+ P PPP + G PGPG P S P P PG SG
Sbjct: 210 MPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSG 267
Score = 32.3 bits (72), Expect = 1.5
Identities = 19/46 (41%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Query: 30 PPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGG 75
PPP P HS G P P +E +S PA+ P++ SSG GG
Sbjct: 108 PPPSPMDQHSQGY-PSP-LGGSEHASSPVPASGPSSGPQMSSGPGG 151
>gi|192807320 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform F [Homo sapiens]
Length = 1613
Score = 85.1 bits (209), Expect = 2e-16
Identities = 80/248 (32%), Positives = 91/248 (36%), Gaps = 40/248 (16%)
Query: 429 GRGSHGQTPSPGALPL-GRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPP 487
G H +P P + P G Q S P G P P G GP P Q Q R
Sbjct: 125 GGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQI 184
Query: 488 QGQQHLSGLGPPAGSPLPQRLPSPTSAPQ-QPASQAAPPTQGQGRQSRPVAGGPGAPPAA 546
+ L+ G PLP L + P Q PT S A GPG P
Sbjct: 185 MAYKMLA-----RGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVS---ATGPGPGPGP 236
Query: 547 RPPASPSPQRQAGPPQATRQTSVSGP--APPKASGAPPG--GQQRQGPPQKPPGPAGPTR 602
P P P PP +R + GP PP SG PPG GQ GPP+ P P GP
Sbjct: 237 GPGPGPGP----APPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPK--PWPEGPMA 290
Query: 603 QASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKA 662
A+ PT+ + P P GRP P PPA A P P
Sbjct: 291 NAA---------APTSTPQKLIPPQPTGRPSP----------APPAVPPAASPVMPPQTQ 331
Query: 663 SPAQ-AQP 669
SP Q AQP
Sbjct: 332 SPGQPAQP 339
Score = 60.5 bits (145), Expect = 5e-09
Identities = 68/211 (32%), Positives = 83/211 (39%), Gaps = 35/211 (16%)
Query: 398 HQDEDKQLIVELVVNKM---AQALPRQRQRDASPGRGSHGQTPSPGALPLGRQTSQQPAG 454
+Q++ QL +++ KM Q LP Q G+ P PG Q P
Sbjct: 173 NQNQLHQLRAQIMAYKMLARGQPLPDHLQMAVQ------GKRPMPG------MQQQMPTL 220
Query: 455 PP---AQQRPPPQGGP-PQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSP-LPQRLP 509
PP + P P GP P PGPGP PP RP G ++ GP P +P + P
Sbjct: 221 PPPSVSATGPGPGPGPGPGPGPGP---APPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPP 277
Query: 510 S--PTSAPQQPASQAAPPTQGQGRQSRPVAGG--PGAPPAARPPASPSPQRQAGPPQATR 565
P P+ P + AA PT + P G APPA P ASP PPQ
Sbjct: 278 GGPPKPWPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPAVPPAASP-----VMPPQT-- 330
Query: 566 QTSVSGPAPPKASGAPPGGQQRQGPPQKPPG 596
S PA P Q R P QKP G
Sbjct: 331 -QSPGQPAQPAPMVPLHQKQSRITPIQKPRG 360
Score = 58.5 bits (140), Expect = 2e-08
Identities = 72/247 (29%), Positives = 86/247 (34%), Gaps = 44/247 (17%)
Query: 462 PPQGGPPQPGPGP---QRQGPPLQQRPPPQGQQHLSGLG-----PPAGSPLPQRLPSPTS 513
PP GG P+PGP P G L P P S +G P AG P+P + P
Sbjct: 6 PPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQ--GPGG 63
Query: 514 APQQPASQAAPPTQG----------QGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQA 563
PQ Q P + + Q + + G PP SP Q G P
Sbjct: 64 YPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGYPSP 123
Query: 564 TRQTS-VSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQ-AGPVPRTGPPTTQ-- 619
+ S P P ASG G Q GP P A P Q GP P Q
Sbjct: 124 LGGSEHASSPVP--ASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLR 181
Query: 620 ------------QPRPSGPGPA---GRPKPQLAQKPSQDVPPPATAAAG-GP-PHPQLKA 662
QP P A RP P + Q+ +PPP+ +A G GP P P
Sbjct: 182 AQIMAYKMLARGQPLPDHLQMAVQGKRPMPGM-QQQMPTLPPPSVSATGPGPGPGPGPGP 240
Query: 663 SPAQAQP 669
P A P
Sbjct: 241 GPGPAPP 247
Score = 34.3 bits (77), Expect = 0.38
Identities = 33/124 (26%), Positives = 46/124 (37%), Gaps = 24/124 (19%)
Query: 569 VSGPAPPKASGAPPGGQQRQGP-PQKPPGPA-GPTRQASQAGPVPRTGPPTTQQPRPSGP 626
+S P PP PG GP P GP+ GP+ ++ + P GPP+ P P+
Sbjct: 1 MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPT-Q 59
Query: 627 GPAGRPKPQLAQ--KPSQDVPPPAT-------------------AAAGGPPHPQLKASPA 665
GP G P+ + Q KP + + A G PP P + S
Sbjct: 60 GPGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQG 119
Query: 666 QAQP 669
P
Sbjct: 120 YPSP 123
Score = 33.1 bits (74), Expect = 0.85
Identities = 19/51 (37%), Positives = 23/51 (45%), Gaps = 7/51 (13%)
Query: 30 PPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAA------PSPGSSGGG 74
P PP G PG +PGPG + G +P SP + PSPG G
Sbjct: 4 PDPPLGGTPRPGPSPGPGPSPG-AMLGPSPGPSPGSAHSMMGPSPGPPSAG 53
Score = 33.1 bits (74), Expect = 0.85
Identities = 19/53 (35%), Positives = 24/53 (45%), Gaps = 4/53 (7%)
Query: 28 PQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPG----SSGGGGF 76
P+P P P SPGA GP + S+ SP PS G + G GG+
Sbjct: 12 PRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQGPGGY 64
Score = 33.1 bits (74), Expect = 0.85
Identities = 19/58 (32%), Positives = 22/58 (37%), Gaps = 7/58 (12%)
Query: 22 MTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAAS-------PAAPSPGSSG 72
M +Q+ P PPP + G PGPG P S P P PG SG
Sbjct: 210 MPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMPPPGPSG 267
Score = 32.3 bits (72), Expect = 1.5
Identities = 19/46 (41%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Query: 30 PPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGG 75
PPP P HS G P P +E +S PA+ P++ SSG GG
Sbjct: 108 PPPSPMDQHSQGY-PSP-LGGSEHASSPVPASGPSSGPQMSSGPGG 151
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.132 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,503,040
Number of Sequences: 37866
Number of extensions: 3312810
Number of successful extensions: 94553
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1312
Number of HSP's successfully gapped in prelim test: 3190
Number of HSP's that attempted gapping in prelim test: 19444
Number of HSP's gapped (non-prelim): 35714
length of query: 669
length of database: 18,247,518
effective HSP length: 109
effective length of query: 560
effective length of database: 14,120,124
effective search space: 7907269440
effective search space used: 7907269440
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.