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Search of human proteins with 19923621
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19923621 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
steroid delta-isomerase 7 isoform a [Homo sapiens]
(369 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19923621 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and s... 759 0.0
gi|218563686 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and ... 365 e-101
gi|218563684 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and ... 365 e-101
gi|4504507 3 beta-hydroxysteroid dehydrogenase 1 [Homo sapiens] 246 2e-65
gi|4504509 3 beta-hydroxysteroid dehydrogenase 2 [Homo sapiens] 241 1e-63
gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo s... 125 5e-29
gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo sap... 125 5e-29
gi|116268111 short chain dehydrogenase/reductase family 42E, mem... 123 3e-28
gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo ... 112 5e-25
gi|239756515 PREDICTED: similar to Putative 3-beta-HSD family pr... 112 7e-25
gi|239751020 PREDICTED: hypothetical protein XP_002347673 [Homo ... 112 7e-25
gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens] 48 2e-05
gi|56118217 UDP-galactose-4-epimerase [Homo sapiens] 41 0.002
gi|56237023 UDP-galactose-4-epimerase [Homo sapiens] 41 0.002
gi|189083684 UDP-galactose-4-epimerase [Homo sapiens] 41 0.002
gi|4502419 biliverdin reductase B (flavin reductase (NADPH)) [Ho... 32 1.2
gi|98986461 neurogenic differentiation 2 [Homo sapiens] 30 4.5
gi|26051273 voltage-gated potassium channel, subfamily H, member... 29 5.9
gi|26051271 voltage-gated potassium channel, subfamily H, member... 29 5.9
gi|4557729 voltage-gated potassium channel, subfamily H, member ... 29 5.9
gi|239747656 PREDICTED: similar to mCG116201 [Homo sapiens] 29 5.9
gi|164419758 bromodomain containing 2 [Homo sapiens] 29 5.9
gi|4826806 bromodomain containing 2 [Homo sapiens] 29 5.9
gi|13540549 potassium voltage-gated channel, subfamily H, member... 29 5.9
gi|27886651 potassium voltage-gated channel, subfamily H, member... 29 5.9
gi|32698704 tectonin beta-propeller repeat containing 1 [Homo sa... 29 7.7
gi|7662280 histone deacetylase 9 isoform 3 [Homo sapiens] 29 7.7
gi|17158041 histone deacetylase 9 isoform 2 [Homo sapiens] 29 7.7
gi|30795204 histone deacetylase 9 isoform 5 [Homo sapiens] 29 7.7
gi|17158039 histone deacetylase 9 isoform 1 [Homo sapiens] 29 7.7
>gi|19923621 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
steroid delta-isomerase 7 isoform a [Homo sapiens]
Length = 369
Score = 759 bits (1961), Expect = 0.0
Identities = 369/369 (100%), Positives = 369/369 (100%)
Query: 1 MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRV 60
MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRV
Sbjct: 1 MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRV 60
Query: 61 TAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTG 120
TAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTG
Sbjct: 61 TAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTG 120
Query: 121 TRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRKVRG 180
TRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRKVRG
Sbjct: 121 TRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRKVRG 180
Query: 181 GLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWMHVL 240
GLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWMHVL
Sbjct: 181 GLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWMHVL 240
Query: 241 AARELEQRATLMGGQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLLPYWLLVFLAA 300
AARELEQRATLMGGQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLLPYWLLVFLAA
Sbjct: 241 AARELEQRATLMGGQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLLPYWLLVFLAA 300
Query: 301 LNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEPLFSWEDSRTRTILW 360
LNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEPLFSWEDSRTRTILW
Sbjct: 301 LNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEPLFSWEDSRTRTILW 360
Query: 361 VQAATGSAQ 369
VQAATGSAQ
Sbjct: 361 VQAATGSAQ 369
>gi|218563686 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
steroid delta-isomerase 7 isoform b [Homo sapiens]
Length = 196
Score = 365 bits (938), Expect = e-101
Identities = 181/187 (96%), Positives = 181/187 (96%), Gaps = 2/187 (1%)
Query: 1 MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRV 60
MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRV
Sbjct: 1 MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRV 60
Query: 61 TAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTG 120
TAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTG
Sbjct: 61 TAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTG 120
Query: 121 TRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRKVRG 180
TRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRK
Sbjct: 121 TRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRKAM- 179
Query: 181 GLPLVTC 187
LP TC
Sbjct: 180 -LPGCTC 185
>gi|218563684 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
steroid delta-isomerase 7 isoform b [Homo sapiens]
Length = 196
Score = 365 bits (938), Expect = e-101
Identities = 181/187 (96%), Positives = 181/187 (96%), Gaps = 2/187 (1%)
Query: 1 MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRV 60
MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRV
Sbjct: 1 MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRV 60
Query: 61 TAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTG 120
TAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTG
Sbjct: 61 TAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTG 120
Query: 121 TRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRKVRG 180
TRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRK
Sbjct: 121 TRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRKAM- 179
Query: 181 GLPLVTC 187
LP TC
Sbjct: 180 -LPGCTC 185
>gi|4504507 3 beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
Length = 373
Score = 246 bits (628), Expect = 2e-65
Identities = 139/354 (39%), Positives = 207/354 (58%), Gaps = 8/354 (2%)
Query: 13 LVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKT---GPVRVTAIQGDVTQ 69
LVTG GFLG+ ++R+L+ +E L E+RV D+ GP L E + ++T ++GD+
Sbjct: 7 LVTGAGGFLGQRIIRLLV-KEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLEGDILD 65
Query: 70 AHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSS 129
+ A V+IHTA ++DVFG ++I VNV+GT+ ++EACVQ +YTSS
Sbjct: 66 EPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTSS 125
Query: 130 MEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRKVRGGLPLVTCAL 189
+EV GPN+ G+E+ P E PYP SK LAE VL ANG ++ G L TCAL
Sbjct: 126 IEVAGPNSYKEIIQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANGWNLKNGGTLYTCAL 185
Query: 190 RPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWMHVLAARELE--Q 247
RP IYGEG + + + L G + ++ VYVGNVAW H+LA R L+ +
Sbjct: 186 RPMYIYGEGSRFLSASINEALNNNG-ILSSVGKFSTVNPVYVGNVAWAHILALRALQDPK 244
Query: 248 RATLMGGQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLLPYWLLVFLAALNALLQW 307
+A + GQ Y+ D +P++SY++ N GLRL +R P L+ ++ L ++ +
Sbjct: 245 KAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRL-DSRWSFPLSLMYWIGFLLEIVSF 303
Query: 308 LLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEPLFSWEDSRTRTILWV 361
LLRP+ Y P N + + ++N+ FT S KAQR Y+PL+SWE+++ +T+ WV
Sbjct: 304 LLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWV 357
>gi|4504509 3 beta-hydroxysteroid dehydrogenase 2 [Homo sapiens]
Length = 372
Score = 241 bits (614), Expect = 1e-63
Identities = 140/354 (39%), Positives = 204/354 (57%), Gaps = 8/354 (2%)
Query: 13 LVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKT---GPVRVTAIQGDVTQ 69
LVTG G LG+ +VR+L++ E L E+R D+ P L E + ++T ++GD+
Sbjct: 6 LVTGAGGLLGQRIVRLLVE-EKELKEIRALDKAFRPELREEFSKLQNRTKLTVLEGDILD 64
Query: 70 AHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSS 129
+ A VVIHTA ++DVFG ++I VNV+GT+ ++EACVQ +YTSS
Sbjct: 65 EPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTSS 124
Query: 130 MEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRKVRGGLPLVTCAL 189
+EV GPN+ G+E+ P E PYP SK LAE VL ANG ++ G L TCAL
Sbjct: 125 IEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTLYTCAL 184
Query: 190 RPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWMHVLAARELE--Q 247
RPT IYGEG + + L G + ++ VYVGNVAW H+LA R L +
Sbjct: 185 RPTYIYGEGGPFLSASINEALNNNG-ILSSVGKFSTVNPVYVGNVAWAHILALRALRDPK 243
Query: 248 RATLMGGQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLLPYWLLVFLAALNALLQW 307
+A + GQ Y+ D +P++SY++ N GLRL +R LP L+ ++ L ++ +
Sbjct: 244 KAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRL-DSRWSLPLTLMYWIGFLLEVVSF 302
Query: 308 LLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEPLFSWEDSRTRTILWV 361
LL P+ Y P N +T+ ++N+ FT S KAQR Y+PL+SWE+++ +T+ WV
Sbjct: 303 LLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWV 356
>gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo
sapiens]
Length = 373
Score = 125 bits (315), Expect = 5e-29
Identities = 103/345 (29%), Positives = 157/345 (45%), Gaps = 23/345 (6%)
Query: 14 VTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVTAIQGDVTQAHEV 73
V GG GFLG+H+V LL R + VFD G +V GD+ ++
Sbjct: 42 VIGGSGFLGQHMVEQLLARGYAVN---VFDIQQG-------FDNPQVRFFLGDLCSRQDL 91
Query: 74 AAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSSMEVV 133
A+ G + V H A + + + VN GT+NVIE C + G + L+ TSS V+
Sbjct: 92 YPALKGVNTVFHCASPPP--SSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVI 149
Query: 134 GPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRKVRGGLPLVTCALRPTG 193
+G G ED PY Y +K L E VL AN + +T A+RP G
Sbjct: 150 ---FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPEKN----FLTTAIRPHG 202
Query: 194 IYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWMHVLAARELEQRATLMG 253
I+G + + R G F +V NV H+LAA +L + +TL G
Sbjct: 203 IFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLSRDSTL-G 261
Query: 254 GQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLLPYWLLVFLAALNALLQWLLRPLV 313
G+ + + P + F L GL + +PYW+ +LA L +LL ++ P++
Sbjct: 262 GKAFHITNDEPI-PFWTFLSRIL--TGLNYEAPKYHIPYWVAYYLALLLSLLVMVISPVI 318
Query: 314 LYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEPLFSWEDSRTRTI 358
P P +A+A T S ++A++ GY+PL + +D+ RT+
Sbjct: 319 QLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAMERTV 363
>gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo
sapiens]
Length = 373
Score = 125 bits (315), Expect = 5e-29
Identities = 103/345 (29%), Positives = 157/345 (45%), Gaps = 23/345 (6%)
Query: 14 VTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVTAIQGDVTQAHEV 73
V GG GFLG+H+V LL R + VFD G +V GD+ ++
Sbjct: 42 VIGGSGFLGQHMVEQLLARGYAVN---VFDIQQG-------FDNPQVRFFLGDLCSRQDL 91
Query: 74 AAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSSMEVV 133
A+ G + V H A + + + VN GT+NVIE C + G + L+ TSS V+
Sbjct: 92 YPALKGVNTVFHCASPPP--SSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVI 149
Query: 134 GPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRKVRGGLPLVTCALRPTG 193
+G G ED PY Y +K L E VL AN + +T A+RP G
Sbjct: 150 ---FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPEKN----FLTTAIRPHG 202
Query: 194 IYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWMHVLAARELEQRATLMG 253
I+G + + R G F +V NV H+LAA +L + +TL G
Sbjct: 203 IFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLSRDSTL-G 261
Query: 254 GQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLLPYWLLVFLAALNALLQWLLRPLV 313
G+ + + P + F L GL + +PYW+ +LA L +LL ++ P++
Sbjct: 262 GKAFHITNDEPI-PFWTFLSRIL--TGLNYEAPKYHIPYWVAYYLALLLSLLVMVISPVI 318
Query: 314 LYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEPLFSWEDSRTRTI 358
P P +A+A T S ++A++ GY+PL + +D+ RT+
Sbjct: 319 QLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAMERTV 363
>gi|116268111 short chain dehydrogenase/reductase family 42E, member
1 [Homo sapiens]
Length = 393
Score = 123 bits (308), Expect = 3e-28
Identities = 116/356 (32%), Positives = 163/356 (45%), Gaps = 33/356 (9%)
Query: 3 DSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVTA 62
D ++QK L+TGG G+ G + L Q + +FD +T P +
Sbjct: 2 DPKRSQKESVLITGGSGYFGFRLGCALNQNGVHV---ILFDIS-----SPAQTIPEGIKF 53
Query: 63 IQGDVTQAHEVAAAVAGAHV--VIHTAGLVDVFGRA--SPKTIHEVNVQGTRNVIEACVQ 118
IQGD+ +V A A V V H A + GR + I EVNV+GT N+++ C +
Sbjct: 54 IQGDIRHLSDVEKAFQDADVTCVFHIASY-GMSGREQLNRNLIKEVNVRGTDNILQVCQR 112
Query: 119 TGTRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHP--YPCSKALAEWLVLEANGR 176
LVYTS+ V+ G G+E PY +H HP Y +K++AE VLEAN
Sbjct: 113 RRVPRLVYTSTFNVI---FGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANAT 169
Query: 177 KV-RGGLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAI---PASVEHGRVYVG 232
+ RG L TCALRP GIYG G Q R R + LF+ + P S+ V+V
Sbjct: 170 PLDRGDGVLRTCALRPAGIYGPGEQ--RHLPRIVSYIEKGLFKFVYGDPRSLVE-FVHVD 226
Query: 233 NVAWMHVLAARELE-QRATLMGGQVYFCYDGSPYRSYEDFNMEFLGPC--GLRLVGARPL 289
N+ H+LA+ L + + GQ YF DG P N EF P GL
Sbjct: 227 NLVQAHILASEALRADKGHIASGQPYFISDGRPVN-----NFEFFRPLVEGLGYTFPSTR 281
Query: 290 LPYWLLVFLAALNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYE 345
LP L+ A L ++ ++L L + P L + T S +KA++ GY+
Sbjct: 282 LPLTLVYCFAFLTEMVHFILGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYK 337
>gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo
sapiens]
Length = 422
Score = 112 bits (280), Expect = 5e-25
Identities = 110/372 (29%), Positives = 163/372 (43%), Gaps = 27/372 (7%)
Query: 2 ADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVT 61
A +A + LVTGG G+LG + L + + + D+ W +T
Sbjct: 26 AKPTKAARQKVLVTGGGGYLGFSLGSHLAKSGT---SVILLDRRRPQWELSPET-----K 77
Query: 62 AIQGDVTQAHEVAAAVAGAHVVIHTAGL-VDVFGRASPKTIHEVNVQGTRNVIEACVQTG 120
IQ DV + A G V H A + + + I +NV GT+ VI+ CV+
Sbjct: 78 FIQADVRDEEALYRAFEGVDCVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRRR 137
Query: 121 TRFLVYTSSMEVVGPNTKGHPFYRGNEDT-PYEAVHRHP--YPCSKALAEWLVLEANGRK 177
L+YTS++ V G P +G+ED+ PY + H Y +KA+A+ L L ANG
Sbjct: 138 VPRLIYTSTVNVA---FGGKPIEQGDEDSVPYFPLDEHVDHYSRTKAIADQLTLMANGMP 194
Query: 178 VRGGLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWM 237
+ GG L TC LRP GIYG Q ++ ++FR V+V N+
Sbjct: 195 LPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKARMNWVHVHNLVQA 254
Query: 238 HVLAAREL-EQRATLMGGQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLL--PYWL 294
HVLAA L + + GQ Y+ DG + E++ P +L ++P + P
Sbjct: 255 HVLAAEALTTAKGYVASGQAYYINDGESVNLF-----EWMAPLFEKLGYSQPWIQVPTSW 309
Query: 295 LVFLAALNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEP-LFSWEDS 353
+ AA+ L LRP+ PLL + T T KA+ GY P F + D+
Sbjct: 310 VYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAPDKFRFADA 369
Query: 354 RTRTILWVQAAT 365
L+VQ+ T
Sbjct: 370 ---VELYVQSTT 378
>gi|239756515 PREDICTED: similar to Putative 3-beta-HSD family
protein ENSP00000330812 [Homo sapiens]
Length = 422
Score = 112 bits (279), Expect = 7e-25
Identities = 110/372 (29%), Positives = 163/372 (43%), Gaps = 27/372 (7%)
Query: 2 ADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVT 61
A +A + LVTGG G+LG + L + + + D+ W +T
Sbjct: 26 AKPTKAARQKVLVTGGGGYLGFSLGSHLAKSGT---SVILLDRRRPQWELSPET-----K 77
Query: 62 AIQGDVTQAHEVAAAVAGAHVVIHTAGL-VDVFGRASPKTIHEVNVQGTRNVIEACVQTG 120
IQ DV + A G V H A + + + I +NV GT+ VI+ CV+
Sbjct: 78 FIQADVRDEEALYHAFEGVDCVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRRR 137
Query: 121 TRFLVYTSSMEVVGPNTKGHPFYRGNEDT-PYEAVHRHP--YPCSKALAEWLVLEANGRK 177
L+YTS++ V G P +G+ED+ PY + H Y +KA+A+ L L ANG
Sbjct: 138 VPRLIYTSTVNVA---FGGKPIEQGDEDSVPYFPLDEHVDHYSRTKAIADQLTLMANGMP 194
Query: 178 VRGGLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWM 237
+ GG L TC LRP GIYG Q ++ ++FR V+V N+
Sbjct: 195 LPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKARMNWVHVHNLVQA 254
Query: 238 HVLAAREL-EQRATLMGGQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLL--PYWL 294
HVLAA L + + GQ Y+ DG + E++ P +L ++P + P
Sbjct: 255 HVLAAEALTTAKGYVASGQAYYINDGESVNLF-----EWMAPLFEKLGYSQPWIQVPTSW 309
Query: 295 LVFLAALNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEP-LFSWEDS 353
+ AA+ L LRP+ PLL + T T KA+ GY P F + D+
Sbjct: 310 VYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAPDKFRFADA 369
Query: 354 RTRTILWVQAAT 365
L+VQ+ T
Sbjct: 370 ---VELYVQSTT 378
>gi|239751020 PREDICTED: hypothetical protein XP_002347673 [Homo
sapiens]
Length = 422
Score = 112 bits (279), Expect = 7e-25
Identities = 110/372 (29%), Positives = 163/372 (43%), Gaps = 27/372 (7%)
Query: 2 ADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVT 61
A +A + LVTGG G+LG + L + + + D+ W +T
Sbjct: 26 AKPTKAARQKVLVTGGGGYLGFSLGSHLAKSGT---SVILLDRRRPQWELSPET-----K 77
Query: 62 AIQGDVTQAHEVAAAVAGAHVVIHTAGL-VDVFGRASPKTIHEVNVQGTRNVIEACVQTG 120
IQ DV + A G V H A + + + I +NV GT+ VI+ CV+
Sbjct: 78 FIQADVRDEEALYHAFEGVDCVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRRR 137
Query: 121 TRFLVYTSSMEVVGPNTKGHPFYRGNEDT-PYEAVHRHP--YPCSKALAEWLVLEANGRK 177
L+YTS++ V G P +G+ED+ PY + H Y +KA+A+ L L ANG
Sbjct: 138 VPRLIYTSTVNVA---FGGKPIEQGDEDSVPYFPLDEHVDHYSRTKAIADQLTLMANGMP 194
Query: 178 VRGGLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWM 237
+ GG L TC LRP GIYG Q ++ ++FR V+V N+
Sbjct: 195 LPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKARMNWVHVHNLVQA 254
Query: 238 HVLAAREL-EQRATLMGGQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLL--PYWL 294
HVLAA L + + GQ Y+ DG + E++ P +L ++P + P
Sbjct: 255 HVLAAEALTTAKGYVASGQAYYINDGESVNLF-----EWMAPLFEKLGYSQPWIQVPTSW 309
Query: 295 LVFLAALNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEP-LFSWEDS 353
+ AA+ L LRP+ PLL + T T KA+ GY P F + D+
Sbjct: 310 VYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAPDKFRFADA 369
Query: 354 RTRTILWVQAAT 365
L+VQ+ T
Sbjct: 370 ---VELYVQSTT 378
>gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens]
Length = 350
Score = 47.8 bits (112), Expect = 2e-05
Identities = 48/165 (29%), Positives = 72/165 (43%), Gaps = 15/165 (9%)
Query: 13 LVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKT--GPVRVTAIQGDVTQA 70
LVTGG GF+ H++ L++ P + + L+ L+T IQGD+ +
Sbjct: 21 LVTGGAGFIASHMIVSLVEDYPNYMIINLDKLDYCASLKNLETISNKQNYKFIQGDICDS 80
Query: 71 H--EVAAAVAGAHVVIHTAGLVDV---FGRASPKTIHEVNVQGTRNVIEACVQTGTRFLV 125
H ++ +V+H A V F RA T VNV GT ++ A + +
Sbjct: 81 HFVKLLFETEKIDIVLHFAAQTHVDLSFVRAFEFTY--VNVYGTHVLVSAAHEARVEKFI 138
Query: 126 YTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLV 170
Y S+ EV G G +E +P + +PY SKA AE V
Sbjct: 139 YVSTDEVYG----GSLDKEFDESSPKQPT--NPYASSKAAAECFV 177
>gi|56118217 UDP-galactose-4-epimerase [Homo sapiens]
Length = 348
Score = 40.8 bits (94), Expect = 0.002
Identities = 50/163 (30%), Positives = 67/163 (41%), Gaps = 35/163 (21%)
Query: 13 LVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHL-------GPWLEELKTGPVRVTAIQG 65
LVTGG G++G H V LL+ G L V + G E L+ RV + G
Sbjct: 6 LVTGGAGYIGSHTVLELLE----AGYLPVVIDNFHNAFRGGGSLPESLR----RVQELTG 57
Query: 66 DVTQAHEVAAAVAGA----------HVVIHTAGLVDVFGRA--SPKTIHEVNVQGTRNVI 113
+ E+ GA VIH AGL V G + P + VN+ GT ++
Sbjct: 58 RSVEFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAV-GESVQKPLDYYRVNLTGTIQLL 116
Query: 114 EACVQTGTRFLVYTSSMEVVG-----PNTKGHPFYRGNEDTPY 151
E G + LV++SS V G P + HP G PY
Sbjct: 117 EIMKAHGVKNLVFSSSATVYGNPQYLPLDEAHP--TGGCTNPY 157
>gi|56237023 UDP-galactose-4-epimerase [Homo sapiens]
Length = 348
Score = 40.8 bits (94), Expect = 0.002
Identities = 50/163 (30%), Positives = 67/163 (41%), Gaps = 35/163 (21%)
Query: 13 LVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHL-------GPWLEELKTGPVRVTAIQG 65
LVTGG G++G H V LL+ G L V + G E L+ RV + G
Sbjct: 6 LVTGGAGYIGSHTVLELLE----AGYLPVVIDNFHNAFRGGGSLPESLR----RVQELTG 57
Query: 66 DVTQAHEVAAAVAGA----------HVVIHTAGLVDVFGRA--SPKTIHEVNVQGTRNVI 113
+ E+ GA VIH AGL V G + P + VN+ GT ++
Sbjct: 58 RSVEFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAV-GESVQKPLDYYRVNLTGTIQLL 116
Query: 114 EACVQTGTRFLVYTSSMEVVG-----PNTKGHPFYRGNEDTPY 151
E G + LV++SS V G P + HP G PY
Sbjct: 117 EIMKAHGVKNLVFSSSATVYGNPQYLPLDEAHP--TGGCTNPY 157
>gi|189083684 UDP-galactose-4-epimerase [Homo sapiens]
Length = 348
Score = 40.8 bits (94), Expect = 0.002
Identities = 50/163 (30%), Positives = 67/163 (41%), Gaps = 35/163 (21%)
Query: 13 LVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHL-------GPWLEELKTGPVRVTAIQG 65
LVTGG G++G H V LL+ G L V + G E L+ RV + G
Sbjct: 6 LVTGGAGYIGSHTVLELLE----AGYLPVVIDNFHNAFRGGGSLPESLR----RVQELTG 57
Query: 66 DVTQAHEVAAAVAGA----------HVVIHTAGLVDVFGRA--SPKTIHEVNVQGTRNVI 113
+ E+ GA VIH AGL V G + P + VN+ GT ++
Sbjct: 58 RSVEFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAV-GESVQKPLDYYRVNLTGTIQLL 116
Query: 114 EACVQTGTRFLVYTSSMEVVG-----PNTKGHPFYRGNEDTPY 151
E G + LV++SS V G P + HP G PY
Sbjct: 117 EIMKAHGVKNLVFSSSATVYGNPQYLPLDEAHP--TGGCTNPY 157
>gi|4502419 biliverdin reductase B (flavin reductase (NADPH)) [Homo
sapiens]
Length = 206
Score = 31.6 bits (70), Expect = 1.2
Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 6/86 (6%)
Query: 56 GPVRVTAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEA 115
GP + GDV QA +V VAG VI L+ SP T+ +G RN++ A
Sbjct: 44 GPRPAHVVVGDVLQAADVDKTVAGQDAVI---VLLGTRNDLSPTTVMS---EGARNIVAA 97
Query: 116 CVQTGTRFLVYTSSMEVVGPNTKGHP 141
G +V +S ++ TK P
Sbjct: 98 MKAHGVDKVVACTSAFLLWDPTKVPP 123
>gi|98986461 neurogenic differentiation 2 [Homo sapiens]
Length = 382
Score = 29.6 bits (65), Expect = 4.5
Identities = 17/58 (29%), Positives = 27/58 (46%), Gaps = 11/58 (18%)
Query: 107 QGTRNVIEACVQTGTRFLVYTSSMEVVGP-NTKGHPFYRGNEDTPYEAVHRHPYPCSK 163
Q T N++ C+Q +R + + G + G PF A+H +PYPCS+
Sbjct: 198 QPTTNLVAGCLQLNSRNFLTEQGADGAGRFHGSGGPF----------AMHPYPYPCSR 245
>gi|26051273 voltage-gated potassium channel, subfamily H, member 2
isoform c [Homo sapiens]
Length = 819
Score = 29.3 bits (64), Expect = 5.9
Identities = 11/38 (28%), Positives = 20/38 (52%)
Query: 288 PLLPYWLLVFLAALNALLQWLLRPLVLYAPLLNPYTLA 325
P + W ++ + A+ WL+ LV+Y + PY+ A
Sbjct: 53 PRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAA 90
>gi|26051271 voltage-gated potassium channel, subfamily H, member 2
isoform b [Homo sapiens]
Length = 888
Score = 29.3 bits (64), Expect = 5.9
Identities = 11/38 (28%), Positives = 20/38 (52%)
Query: 288 PLLPYWLLVFLAALNALLQWLLRPLVLYAPLLNPYTLA 325
P + W ++ + A+ WL+ LV+Y + PY+ A
Sbjct: 393 PRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAA 430
>gi|4557729 voltage-gated potassium channel, subfamily H, member 2
isoform a [Homo sapiens]
Length = 1159
Score = 29.3 bits (64), Expect = 5.9
Identities = 11/38 (28%), Positives = 20/38 (52%)
Query: 288 PLLPYWLLVFLAALNALLQWLLRPLVLYAPLLNPYTLA 325
P + W ++ + A+ WL+ LV+Y + PY+ A
Sbjct: 393 PRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAA 430
>gi|239747656 PREDICTED: similar to mCG116201 [Homo sapiens]
Length = 591
Score = 29.3 bits (64), Expect = 5.9
Identities = 17/36 (47%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Query: 23 EHVVRMLLQREPRLGELRV-FDQHLGPWLEELKTGP 57
EH +R LL R + G LR+ DQ LG ++E LK+ P
Sbjct: 119 EHQIRDLLSRTKKPGGLRIRGDQQLGFYVEGLKSVP 154
>gi|164419758 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 29.3 bits (64), Expect = 5.9
Identities = 11/28 (39%), Positives = 19/28 (67%)
Query: 59 RVTAIQGDVTQAHEVAAAVAGAHVVIHT 86
++ A+QG VT AH+V A + +H ++T
Sbjct: 201 KLAALQGSVTSAHQVPAVSSVSHTALYT 228
>gi|4826806 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 29.3 bits (64), Expect = 5.9
Identities = 11/28 (39%), Positives = 19/28 (67%)
Query: 59 RVTAIQGDVTQAHEVAAAVAGAHVVIHT 86
++ A+QG VT AH+V A + +H ++T
Sbjct: 201 KLAALQGSVTSAHQVPAVSSVSHTALYT 228
>gi|13540549 potassium voltage-gated channel, subfamily H, member 6
isoform 1 [Homo sapiens]
Length = 994
Score = 29.3 bits (64), Expect = 5.9
Identities = 11/38 (28%), Positives = 20/38 (52%)
Query: 288 PLLPYWLLVFLAALNALLQWLLRPLVLYAPLLNPYTLA 325
P + W ++ + A+ WL+ LV+Y + PY+ A
Sbjct: 242 PRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAA 279
>gi|27886651 potassium voltage-gated channel, subfamily H, member 6
isoform 2 [Homo sapiens]
Length = 905
Score = 29.3 bits (64), Expect = 5.9
Identities = 11/38 (28%), Positives = 20/38 (52%)
Query: 288 PLLPYWLLVFLAALNALLQWLLRPLVLYAPLLNPYTLA 325
P + W ++ + A+ WL+ LV+Y + PY+ A
Sbjct: 242 PRIHRWTILHYSPFKAVWDWLILLLVIYTAVFTPYSAA 279
>gi|32698704 tectonin beta-propeller repeat containing 1 [Homo
sapiens]
Length = 1165
Score = 28.9 bits (63), Expect = 7.7
Identities = 19/58 (32%), Positives = 26/58 (44%), Gaps = 5/58 (8%)
Query: 146 NEDTPYEAVHRHPYPCSKALAEWL-----VLEANGRKVRGGLPLVTCALRPTGIYGEG 198
+E +P H HP PC + + ++EAN R V G+ A TG YG G
Sbjct: 743 SEPSPDLEAHEHPLPCDQMFWRQMGGHLRMVEANSRGVVWGIGYDHTAWVYTGGYGGG 800
>gi|7662280 histone deacetylase 9 isoform 3 [Homo sapiens]
Length = 590
Score = 28.9 bits (63), Expect = 7.7
Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 8/84 (9%)
Query: 181 GLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYV--------G 232
GLP V L + E + RQG+ L G +IPAS H V +
Sbjct: 333 GLPAVPSQLNASNSLKEKQKCETQTLRQGVPLPGQYGGSIPASSSHPHVTLEGKPPNSSH 392
Query: 233 NVAWMHVLAARELEQRATLMGGQV 256
H+L ++ Q+ L+ G V
Sbjct: 393 QALLQHLLLKEQMRQQKLLVAGGV 416
>gi|17158041 histone deacetylase 9 isoform 2 [Homo sapiens]
Length = 879
Score = 28.9 bits (63), Expect = 7.7
Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 8/84 (9%)
Query: 181 GLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYV--------G 232
GLP V L + E + RQG+ L G +IPAS H V +
Sbjct: 333 GLPAVPSQLNASNSLKEKQKCETQTLRQGVPLPGQYGGSIPASSSHPHVTLEGKPPNSSH 392
Query: 233 NVAWMHVLAARELEQRATLMGGQV 256
H+L ++ Q+ L+ G V
Sbjct: 393 QALLQHLLLKEQMRQQKLLVAGGV 416
>gi|30795204 histone deacetylase 9 isoform 5 [Homo sapiens]
Length = 1069
Score = 28.9 bits (63), Expect = 7.7
Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 8/84 (9%)
Query: 181 GLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYV--------G 232
GLP V L + E + RQG+ L G +IPAS H V +
Sbjct: 336 GLPAVPSQLNASNSLKEKQKCETQTLRQGVPLPGQYGGSIPASSSHPHVTLEGKPPNSSH 395
Query: 233 NVAWMHVLAARELEQRATLMGGQV 256
H+L ++ Q+ L+ G V
Sbjct: 396 QALLQHLLLKEQMRQQKLLVAGGV 419
>gi|17158039 histone deacetylase 9 isoform 1 [Homo sapiens]
Length = 1011
Score = 28.9 bits (63), Expect = 7.7
Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 8/84 (9%)
Query: 181 GLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYV--------G 232
GLP V L + E + RQG+ L G +IPAS H V +
Sbjct: 333 GLPAVPSQLNASNSLKEKQKCETQTLRQGVPLPGQYGGSIPASSSHPHVTLEGKPPNSSH 392
Query: 233 NVAWMHVLAARELEQRATLMGGQV 256
H+L ++ Q+ L+ G V
Sbjct: 393 QALLQHLLLKEQMRQQKLLVAGGV 416
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.139 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,531,335
Number of Sequences: 37866
Number of extensions: 653687
Number of successful extensions: 1158
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1105
Number of HSP's gapped (non-prelim): 31
length of query: 369
length of database: 18,247,518
effective HSP length: 104
effective length of query: 265
effective length of database: 14,309,454
effective search space: 3792005310
effective search space used: 3792005310
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.