Guide to the Human Genome
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Name: HSD3B1 Sequence: fasta or formatted (373aa) NCBI GI: 4504507
Description:

3 beta-hydroxysteroid dehydrogenase 1

Referenced in:

Adrenals
Organs and Hormones
Ovary, Uterus and Placenta
Steroid Hormones

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.2         23           2
 C cysteine            1.3          5           1
 D aspartate           3.2         12           2
 E glutamate           6.7         25           3
 F phenylalanine       4.3         16           1
 G glycine             6.2         23           2
 H histidine           2.1          8           1
 I isoleucine          6.2         23           2
 K lysine              7.0         26           2
 L leucine            11.3         42           3
 M methionine          1.1          4           1
 N asparagine          5.1         19           3
 P proline             4.8         18           2
 Q glutamine           3.2         12           1
 R arginine            4.6         17           1
 S serine              7.8         29           2
 T threonine           5.4         20           1
 V valine              7.0         26           1
 W tryptophan          2.1          8           1
 Y tyrosine            4.6         17           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   3 beta-hydroxysteroid dehydrogenase 1 
HSD3B2                0.941   3 beta-hydroxysteroid dehydrogenase 2 
HSD3B7                0.302   hydroxy-delta-5-steroid dehydrogenase, 3 beta- and s...
HSD3B7                0.137   hydroxy-delta-5-steroid dehydrogenase, 3 beta- and ...
HSD3B7                0.137   hydroxy-delta-5-steroid dehydrogenase, 3 beta- and ...
SDR42E1               0.133   short chain dehydrogenase/reductase family 42E, mem...
LOC100288072          0.128   PREDICTED: hypothetical protein XP_002343493 
LOC100292512          0.126   PREDICTED: similar to Putative 3-beta-HSD family pr...
LOC100291543          0.126   PREDICTED: hypothetical protein XP_002347673 
NSDHL                 0.109   NAD(P) dependent steroid dehydrogenase-like 
NSDHL                 0.109   NAD(P) dependent steroid dehydrogenase-like 
TGDS                  0.052   TDP-glucose 4,6-dehydratase 
GALE                  0.016   UDP-galactose-4-epimerase 
GALE                  0.016   UDP-galactose-4-epimerase 
GALE                  0.016   UDP-galactose-4-epimerase 
FAR2                  0.016   fatty acyl CoA reductase 2 
GRPR                  0.014   gastrin-releasing peptide receptor 
LOC100293905          0.014   PREDICTED: similar to gastrin-releasing peptide rec...
CSPG4                 0.007   chondroitin sulfate proteoglycan 4 
FAR1                  0.007   fatty acyl CoA reductase 1 
PEX6                  0.005   peroxisomal biogenesis factor 6 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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