BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|19923597 Sin3A-associated protein, 130kDa isoform b [Homo sapiens] (1048 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|19923597 Sin3A-associated protein, 130kDa isoform b [Homo sap... 2063 0.0 gi|225579127 Sin3A-associated protein, 130kDa isoform a [Homo sa... 2046 0.0 gi|91982772 mucin 17 [Homo sapiens] 125 2e-28 gi|116284392 mucin 2 precursor [Homo sapiens] 120 5e-27 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 116 1e-25 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 116 1e-25 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 116 1e-25 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 116 1e-25 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 100 1e-20 gi|167736355 mucin 4 isoform a [Homo sapiens] 97 1e-19 gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 96 1e-19 gi|151301154 mucin 6, gastric [Homo sapiens] 96 2e-19 gi|163965366 nascent polypeptide-associated complex alpha subuni... 96 2e-19 gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 92 2e-18 gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] 85 3e-16 gi|83367077 mucin 16 [Homo sapiens] 84 7e-16 gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 82 3e-15 gi|161019170 mucin 5AC [Homo sapiens] 80 1e-14 gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 77 8e-14 gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 74 6e-13 gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens] 74 6e-13 gi|148612879 polyhomeotic like 3 [Homo sapiens] 74 6e-13 gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi... 74 9e-13 gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens] 74 9e-13 gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens] 71 5e-12 gi|169205253 PREDICTED: hypothetical protein [Homo sapiens] 70 8e-12 gi|239752529 PREDICTED: similar to mucin [Homo sapiens] 69 2e-11 gi|56549668 AT rich interactive domain 2 (ARID, RFX-like) [Homo ... 69 2e-11 gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens] 69 2e-11 gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 68 4e-11 >gi|19923597 Sin3A-associated protein, 130kDa isoform b [Homo sapiens] Length = 1048 Score = 2063 bits (5346), Expect = 0.0 Identities = 1048/1048 (100%), Positives = 1048/1048 (100%) Query: 1 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP 60 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP Sbjct: 1 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP 60 Query: 61 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA 120 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA Sbjct: 61 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA 120 Query: 121 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI 180 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI Sbjct: 121 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI 180 Query: 181 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM 240 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM Sbjct: 181 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM 240 Query: 241 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS 300 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS Sbjct: 241 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS 300 Query: 301 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL 360 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL Sbjct: 301 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL 360 Query: 361 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA 420 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA Sbjct: 361 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA 420 Query: 421 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS 480 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS Sbjct: 421 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS 480 Query: 481 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV 540 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV Sbjct: 481 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV 540 Query: 541 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ 600 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ Sbjct: 541 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ 600 Query: 601 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP 660 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP Sbjct: 601 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP 660 Query: 661 AQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQP 720 AQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQP Sbjct: 661 AQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQP 720 Query: 721 PPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVP 780 PPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVP Sbjct: 721 PPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVP 780 Query: 781 EIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQ 840 EIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQ Sbjct: 781 EIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQ 840 Query: 841 HVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLL 900 HVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLL Sbjct: 841 HVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLL 900 Query: 901 RHYRNPWKAAYHHFQRYSDVRVKEEKKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTN 960 RHYRNPWKAAYHHFQRYSDVRVKEEKKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTN Sbjct: 901 RHYRNPWKAAYHHFQRYSDVRVKEEKKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTN 960 Query: 961 LEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARDSMLKVL 1020 LEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARDSMLKVL Sbjct: 961 LEHDVYERLTNLQEGIIPKKKAATDDDLHRINELIQGNMQRCKLVMDQISEARDSMLKVL 1020 Query: 1021 DHKDRVLKLLNKNGTVKKVSKLKRKEKV 1048 DHKDRVLKLLNKNGTVKKVSKLKRKEKV Sbjct: 1021 DHKDRVLKLLNKNGTVKKVSKLKRKEKV 1048 >gi|225579127 Sin3A-associated protein, 130kDa isoform a [Homo sapiens] Length = 1083 Score = 2046 bits (5300), Expect = 0.0 Identities = 1048/1083 (96%), Positives = 1048/1083 (96%), Gaps = 35/1083 (3%) Query: 1 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP 60 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP Sbjct: 1 MGPPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINP 60 Query: 61 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA 120 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA Sbjct: 61 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA 120 Query: 121 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI 180 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI Sbjct: 121 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI 180 Query: 181 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM 240 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM Sbjct: 181 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM 240 Query: 241 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS 300 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS Sbjct: 241 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS 300 Query: 301 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL 360 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL Sbjct: 301 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL 360 Query: 361 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA 420 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA Sbjct: 361 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA 420 Query: 421 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS 480 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS Sbjct: 421 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS 480 Query: 481 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV 540 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV Sbjct: 481 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV 540 Query: 541 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ 600 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ Sbjct: 541 HLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ 600 Query: 601 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP 660 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP Sbjct: 601 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAP 660 Query: 661 AQGSSPRPSILRKKPATD-----------------------------------GAKPKSE 685 AQGSSPRPSILRKKPATD GAKPKSE Sbjct: 661 AQGSSPRPSILRKKPATDGMAVRKTLIPPQPPDVASPRVESSMRSTSGSPRPAGAKPKSE 720 Query: 686 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP 745 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP Sbjct: 721 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP 780 Query: 746 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT 805 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT Sbjct: 781 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT 840 Query: 806 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS 865 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS Sbjct: 841 NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKS 900 Query: 866 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE 925 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE Sbjct: 901 LLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYSDVRVKEE 960 Query: 926 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD 985 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD Sbjct: 961 KKAMLQEIANQKGVSCRAQGWKVHLCAAQLLQLTNLEHDVYERLTNLQEGIIPKKKAATD 1020 Query: 986 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK 1045 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK Sbjct: 1021 DDLHRINELIQGNMQRCKLVMDQISEARDSMLKVLDHKDRVLKLLNKNGTVKKVSKLKRK 1080 Query: 1046 EKV 1048 EKV Sbjct: 1081 EKV 1083 >gi|91982772 mucin 17 [Homo sapiens] Length = 4493 Score = 125 bits (314), Expect = 2e-28 Identities = 201/915 (21%), Positives = 346/915 (37%), Gaps = 107/915 (11%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQ--SREEKQEP 95 P T + + + +ANS ++ L + +E S+ + +S++ + + P Sbjct: 2693 PLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTP 2752 Query: 96 VVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPL-SFSEGLMKPPPKPTMPSRPI 154 + + + S+ + S T V + P T A + +E P P+ S P+ Sbjct: 2753 LTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPL 2812 Query: 155 APAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSII 214 P + + G ++ T P ++ PV T + P+ I+ I Sbjct: 2813 TSMPVNHTPVASSEAGTLSTT-----PVDTSTPVTTSTKASSSPTTAEGIVVP------I 2861 Query: 215 RSNAPGPPL--HIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAA--TAQPAVQHIIH 270 + + G L I S P ++ A+ +S++ V T + T+ ++ T I Sbjct: 2862 STASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPIS 2921 Query: 271 QPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAI 330 P + P+T+ V + ++T + +PV T T + A S PT + ++ Sbjct: 2922 TPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTA----EGTSM 2977 Query: 331 SIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVA---PILATN 387 I P + R T +++ + P + L +T T TPV +T A P A Sbjct: 2978 PISTPGERRTPLTSMSVSTMPVASSEASTL----SRTPADTSTPVTTSTEASSSPTTAEG 3033 Query: 388 T-IPSATTA-GSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRI 445 T IP +T + GS T P ST + +P S+ +T SN PV +T T Sbjct: 3034 TGIPISTPSEGSTPLTSIPVST-TPVAIPEASTLSTTPVDSNSPV-------VTSTEVSS 3085 Query: 446 QPDYPAERSSLIPISGHRASPNP---VAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAH 502 P PAE +S+ PIS + P V + T ++ + T P AH Sbjct: 3086 SPT-PAEGTSM-PISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAH 3143 Query: 503 TYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVAS---TVHLNPMQLMT-----VDASH 554 + + S P P + + T + V+S T+ P+ T +A+ Sbjct: 3144 SSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATS 3203 Query: 555 ARHIQGIQ-PAPISTQGIQP---APIGTPGI---QPAPLGTQGIHSATPINTQ----GLQ 603 + +G P ++G+ P P+ + + + L T + S TP+ T Sbjct: 3204 STTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSP 3263 Query: 604 PAPMGTQQPQP---EGKTSAVVLADGATIVANPISNPFSAAPAAT-TVVQTHSQSASTNA 659 P GT P EG T + T VA+ ++ S PA T T V T+SQ++S+ Sbjct: 3264 PTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPP 3323 Query: 660 PAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPT-AQ 718 A G+S S ++G+ P + + S V+ T+S D T T A Sbjct: 3324 IADGTSMPTSTY-----SEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEAS 3378 Query: 719 QPPPTIPTMIAAASPPSQPAVALSTIPGAVP--ITPPITTIAAAPPPSVTV-------GG 769 P T S PS+ L+++P + ++ + T++ P S T+ Sbjct: 3379 LSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASS 3438 Query: 770 SLSSVLGPPVPEIKVKEEVEPMDIM-----------------RPVSAVPPLATNTVSPSL 812 S + G +P E P+ IM PV P+ T++ + S Sbjct: 3439 SPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSS 3498 Query: 813 ALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTD--------DEKSTAK 864 A SMPTS G++P +++ E + T D + S++ Sbjct: 3499 PTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSP 3558 Query: 865 SLLVKAEKRKSPPKE 879 + L R S P E Sbjct: 3559 ATLQVTTMRMSTPSE 3573 Score = 114 bits (286), Expect = 4e-25 Identities = 196/916 (21%), Positives = 333/916 (36%), Gaps = 80/916 (8%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEK--QEP 95 P T + + ++A+S + L+ ++ ++ S+ + SL + P Sbjct: 217 PLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTP 276 Query: 96 VVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPL-SFSEGLMKPPPKPTMPSRPI 154 + P + ++S+ + S TP A P T A + +EG P T S P+ Sbjct: 277 LTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPL 336 Query: 155 APAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSII 214 P ST+ + T E S + + +T+ PS+L ++ Sbjct: 337 TSTPASTMPV---------ATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTST 387 Query: 215 RSNAPGPPLHIGASHLPRGAAAAAVMSSSKVT--TVLRPTSQLPNAATAQPAVQHIIHQP 272 S P ++ S + ++ A+ S+ V T + S+ ++ T P Sbjct: 388 LSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTP 447 Query: 273 IQSRPPVTTSNAIPPAVVATVSATRAQSPVITTT-AAHATDSALSRPTLSIQHPPSAAIS 331 + P+T+ V ++ ++ + +PV + T +T+++ S PT + P++ S Sbjct: 448 SEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPS 507 Query: 332 -----------IQRPAQSRDVTTRITLP---SHPALGTPK-QQLHTMAQKTIFSTGTPVA 376 P S + +T T P S P + + T + T T TP Sbjct: 508 EGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSE 567 Query: 377 AATVAPILATNT-IPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVP 435 +T + +T + ++ A + S T A ++T VT + + SS TA TS +P + Sbjct: 568 GSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTS-MPTSTYSE 626 Query: 436 QQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPS 495 + T TS + A + + S PV T + + + TY Sbjct: 627 RGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEG 686 Query: 496 AYPLAA---HTYTPITSSVSTIRQYPVSAQAP----NSAITAQTGVGVASTVHLNPMQLM 548 + PL + +T +S ST+ PV P A ++ T AS P + Sbjct: 687 STPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGS 746 Query: 549 TVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMG 608 T S + + ST P T + T S +P T+G P+ Sbjct: 747 TPLTSMPVSKTLLTSSEASTLSTTPLDTSTH------ITTSTEASCSPTTTEGTS-MPIS 799 Query: 609 TQQPQPEGKTSAVVLADGATIVANPISNPFSAAPA-ATTVVQTHSQSASTNAPAQGSSPR 667 T EG + T V +P ++ S P + + V T ++ +S+ PA+G+S Sbjct: 800 TPS---EGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMP 856 Query: 668 PSI-------LRKKP------ATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVP 714 S L P AT S V +TPVT S E S+ + T ++P Sbjct: 857 TSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGT-SMP 915 Query: 715 ---------PTAQQPPPTIPTMIAAASPPSQPAVALST-IPGAVPITPPITTIAAAPPPS 764 P P T P + + A S V ST + + T TT P+ Sbjct: 916 TSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPT 975 Query: 765 VTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTS 824 T + + PV V PV + PL T+T + S A SMPTS Sbjct: 976 STPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTS 1035 Query: 825 DLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEK-----STAKSLLVKAEKRKSPPKE 879 G++P + ++++ E + T D S A S A+ P Sbjct: 1036 TPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTST 1095 Query: 880 YID-EEGVRYVPVRPR 894 Y + + VPV R Sbjct: 1096 YSEGSTPLTSVPVSTR 1111 Score = 113 bits (283), Expect = 8e-25 Identities = 200/860 (23%), Positives = 331/860 (38%), Gaps = 134/860 (15%) Query: 95 PVVVRPY--PQVQMLST-----HHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKP 147 PV P P+ LST + V ++T ++ +A A T ++SEG P Sbjct: 2521 PVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEG---STPLR 2577 Query: 148 TMP--SRPIAPAPPSTLSLPP-----------KVPGQVTVTMESSIPQASAIPVAT---- 190 +MP ++P+A + STLS P + T ++S+P ++ V+T Sbjct: 2578 SMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTS 2637 Query: 191 --ISGQQGHPSNLHHIMTTNVQMSIIRSNAPGP---PLHIGASHLPRGAAAAAVMSSSKV 245 +S S + TT V + + + G P S +P S+ + Sbjct: 2638 ILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGER---STPL 2694 Query: 246 TTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQ--SPVI 303 T +L T+ L N+ + + P+ + PVTTS A+ S T A+ S I Sbjct: 2695 TNILVSTTLLANSEASTLSTT-----PVDTSTPVTTS------AEASSSPTTAEGTSMRI 2743 Query: 304 TTTAAHATD-SALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHT 362 +T + +T +++ TL + ++ +S S VTT S P T Sbjct: 2744 STPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSP----------T 2793 Query: 363 MAQKTIFSTGTPVAAATVAPILATNTIPSATT-AGSVSHTQAPTSTIVTMTVPSHSSHAT 421 A+ T T TP +T + N P A++ AG++S T TST VT + + SS T Sbjct: 2794 TAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTT 2853 Query: 422 AVTTSNIPVAKVVPQQITHTSPRIQ--PDYPAERSSL--IPISGHRASPNPVAMETRSDN 477 A +P++ TS + P +E S+L P+ + PV T + Sbjct: 2854 AEGIV-VPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVD----TSIPVTTSTEGSS 2908 Query: 478 RPSVPVQFQYFLPTYPPSAYPLAAHTYTPIT---SSVSTIRQYPVSAQAPNSAITAQTGV 534 P+ + T + PL + + + S ST+ PV + P T+ Sbjct: 2909 SPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTP--VTTSAEAS 2966 Query: 535 GVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIG---------TPGIQPAP 585 +T M + T G + P+++ + P+ TP P Sbjct: 2967 SSPTTAEGTSMPIST---------PGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTP 3017 Query: 586 LGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPA-A 644 + T S++P +G P+ T EG T + T VA P ++ S P + Sbjct: 3018 VTTSTEASSSPTTAEGTG-IPISTPS---EGSTPLTSIPVSTTPVAIPEASTLSTTPVDS 3073 Query: 645 TTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVS-METVSN 703 + V T ++ +S+ PA+G+S S ++G+ P + + VS TPVT S + T+S Sbjct: 3074 NSPVVTSTEVSSSPTPAEGTSMPISTY-----SEGSTPLTGVPVS-TTPVTSSAISTLST 3127 Query: 704 QNNDQPTIAVPPT-AQQPPPTIPTMIAAASPPSQPAVALSTIP--------------GAV 748 D T T A P T S PS+ + L+ +P A Sbjct: 3128 TPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSAT 3187 Query: 749 PI--TPPITTIAAAPP---------PSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPV 797 P+ + P+TT A P+ T ++ + PV V + PV Sbjct: 3188 PVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPV 3247 Query: 798 SAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTD 857 + PL T+T + S A SMPTS G++P +++ E + T D Sbjct: 3248 DSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPAD 3307 Query: 858 DEKSTAKSLLVKAEKRKSPP 877 T+ + ++ SPP Sbjct: 3308 ----TSTPVTTYSQASSSPP 3323 Score = 113 bits (282), Expect = 1e-24 Identities = 210/922 (22%), Positives = 343/922 (37%), Gaps = 85/922 (9%) Query: 39 STGLSQAP---SQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSR--EEKQ 93 ST L+ P + +A+S L A + S+ S+ + +S+Q+ E Sbjct: 1513 STALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGS 1572 Query: 94 EPVVVRPYPQVQMLSTHHAVASATPV--------------AVTAPPAHLTPAVPLSFSEG 139 P+ P + ++S+ S TP+ + TA + +T + P S Sbjct: 1573 TPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPL 1632 Query: 140 LMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQ--VTVTMESSIP---QASAIPVATISGQ 194 L P T P+A STLS P +T T SS P + +++P +T + + Sbjct: 1633 LTSIPVSTT----PVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYT-E 1687 Query: 195 QGHPSNLHHIMTTNVQMSIIRSNAPGP---PLHIGASHLPRGAAAAAVMSSSKVTTVLRP 251 P + TT V S I + + P + S R + + +S +T Sbjct: 1688 GRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEG 1747 Query: 252 TSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHAT 311 T+ L + + V + S P+ TS + + AT S T A+ I T Sbjct: 1748 TTPLTSIPVSTTPVLSSEASTL-SATPIDTSTPVTTSTEATSSPTTAEGTSIPT------ 1800 Query: 312 DSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFST 371 S LS + P + + S TT + S T T A+ T +T Sbjct: 1801 -STLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAT 1859 Query: 372 GTPVAAATVAPIL--ATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIP 429 TP +T + +T T+ S+ T ++S T A TST VT T SS T S++P Sbjct: 1860 STPSEGSTALTSIPVSTTTVASSET-NTLSTTPAVTSTPVT-TYAQVSSSPTTADGSSMP 1917 Query: 430 VAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPN-PVAMETRSDNRPSVPVQFQYF 488 + + TS + A S + +S A PV +++ + P+ Sbjct: 1918 TSTPREGRPPLTSIPVSTTTVAS-SEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMP 1976 Query: 489 LPTYPPSAYPLAA---HTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPM 545 P Y + PL + T ++S ST+ PV P A T+ G +T + Sbjct: 1977 TPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTP--ATTSTEGSSSPTTAGGTSI 2034 Query: 546 QLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPA 605 Q T + + G+ P+ST + + T P TQ +S ++ + + Sbjct: 2035 QTST-PSERTTPLAGM---PVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGS 2090 Query: 606 PMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPA-ATTVVQTHSQSASTNAPAQGS 664 M P EG + T VA+P ++ S P + + V T ++ +S+ P +G+ Sbjct: 2091 SMTISAPS-EGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGT 2149 Query: 665 SPRPSIL--RKKP-----------ATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQ--- 708 S + S R+ P A+ S V +TPVT S E S+ + Sbjct: 2150 SMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTS 2209 Query: 709 -----PTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALST-IPGAVPITPPITTIAAAPP 762 P+ P P T+P + + AS S V ST + + T TT Sbjct: 2210 MPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSI 2269 Query: 763 PSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMP 822 P+ T+ + + PV V PV + P T+T + S A SMP Sbjct: 2270 PTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMP 2329 Query: 823 TSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEK-----STAKSLLVKAEKRKSPP 877 TS G +P + ++++ E + T D S A S A+ P Sbjct: 2330 TSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPT 2389 Query: 878 KEYID-EEGVRYVPVRPRPPIT 898 Y + + VPV P ++ Sbjct: 2390 STYSEGSTPLTSVPVSTMPVVS 2411 Score = 113 bits (282), Expect = 1e-24 Identities = 192/859 (22%), Positives = 331/859 (38%), Gaps = 115/859 (13%) Query: 38 PSTGLSQAPSQIANSGSAGL----INPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQ 93 P TG+ + + + +S + L ++ + V + S + E S +S S E Sbjct: 3106 PLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPS--EGS 3163 Query: 94 EPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPT----- 148 P+ P + ++S+ + SATPV + P T A + +EG P P+ Sbjct: 3164 TPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTP 3223 Query: 149 -----MPSRPIAPAPPSTLSLPP---KVPGQVTVTMESSIPQASAIPVATISGQQGH-PS 199 + + P+A + S LS P P + SS P A + T + +G P Sbjct: 3224 LTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPL 3283 Query: 200 NLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNA- 258 + TT V S + + P +S+ VTT + +S P A Sbjct: 3284 TSMPVSTTTVASSETSTLSTTP-----------------ADTSTPVTTYSQASSSPPIAD 3326 Query: 259 ATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTT-AAHATDSALSR 317 T+ P + + P+T + VV++ ++T + +PV T+T +T+++LS Sbjct: 3327 GTSMPTSTY-----SEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSP 3381 Query: 318 PTLSIQHPPSAAIS-----------IQRPAQSRDVTTRITLP----SHPALGTPKQQLHT 362 T P+++ S P S +V T T P + T T Sbjct: 3382 TTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPT 3441 Query: 363 MAQKTIFSTGTPVAAATVAPILATNTIPSATT-AGSVSHTQAPTSTIVTMTVPSHSSHAT 421 +A+ T T T +T I+ +T P A++ A ++S T TST VT + P++SS T Sbjct: 3442 IAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTT 3501 Query: 422 A-VTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSL--IPI-------SGHRASPNPVAM 471 A VT+ A +T+ P +E S+L P+ S +AS +P + Sbjct: 3502 AEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATL 3561 Query: 472 ETRSDNRPSVPVQFQYFLPT-YPPSAYPLAAHTYTPITSSVSTIRQYPVSAQA-----PN 525 + + R S P + L T S Y ++ TP T SV S Q+ P Sbjct: 3562 QV-TTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPP 3620 Query: 526 SAIT--AQTGVGVASTVHLNPMQLMTVDASHARHIQ--------------GIQPAPISTQ 569 IT T V++ + + P+ +V S A + +P++ + Sbjct: 3621 EVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPE 3680 Query: 570 GIQPAPIGTPGIQPAPLGTQGIHSATPINTQG--LQPAPMGTQQPQPEGKTSAVVLADGA 627 G PI TP PL T + + +++G L + T P TS ++ A Sbjct: 3681 G-TTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTPSVVTSTPV---TTSTEAISSSA 3736 Query: 628 TI--VANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSE 685 T+ +S P + TT++ S + T P + PS+ T ++ S Sbjct: 3737 TLDSTTMSVSMPMEISTLGTTILV--STTPVTRFPESSTPSIPSVYTSMSMTTASEGSSS 3794 Query: 686 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP 745 ++ T+ M T S ++ T+ + P + P T+ S P + ST Sbjct: 3795 -PTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLT-STKA 3852 Query: 746 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT 805 G+ I +TTI S++S P+ + V + +++ PPL T Sbjct: 3853 GSFSIPAEVTTIRI----------SITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDT 3902 Query: 806 NTVSPSLALLANNLSMPTS 824 +T A+ ++P + Sbjct: 3903 STTFTPSTDTASTPTIPVA 3921 Score = 112 bits (279), Expect = 2e-24 Identities = 187/881 (21%), Positives = 314/881 (35%), Gaps = 65/881 (7%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSR--EEKQEP 95 P T + + +ANS ++ L N +E S+ + +S+ + E P Sbjct: 984 PLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTP 1043 Query: 96 VVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFS-EGLMKPPPKPTMPSRPI 154 + P + S+ + S TP + P + A S + +G P + S P+ Sbjct: 1044 LTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPL 1103 Query: 155 APAP----------PSTLSLPP---KVPGQVTVTMESSIPQASAIPVATISGQQGHPSNL 201 P STLS P +P + SS A + T +G Sbjct: 1104 TSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLA 1163 Query: 202 HHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATA 261 ++T + +S + P+ + + A++ +++VT++ PTS P + Sbjct: 1164 SMPVSTTLVVSSEANTLSTTPVD-SKTQVATSTEASSPPPTAEVTSM--PTST-PGERST 1219 Query: 262 QPAVQHIIHQPIQSRPPVTTSNA-IPPAVVATVSATRAQSPVITTTAAHATDSALSRPTL 320 + H P+ S T S + + + T SA + SP + T + TL Sbjct: 1220 PLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTL 1279 Query: 321 SIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATV 380 P S + + P S +TT + T A+ T T T T Sbjct: 1280 LTSIPVSTTL-VTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTP 1338 Query: 381 APILATNTIPSATTAGSV-SHTQAPTSTIVTMTVPSHSSHATAVTTS---NIPVAKVVPQ 436 + NT A++A S+ S T ST VT + + SS T+ TS + P P Sbjct: 1339 LTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTP- 1397 Query: 437 QITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSA 496 +T P +E S+L ++P + E S + + P+ + Sbjct: 1398 -LTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTP 1456 Query: 497 YPLAAHTYTPITSS-VSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHA 555 + TP+ +S ST+ PV + NS + T V + T ++ + + Sbjct: 1457 LKSIPVSNTPVANSEASTLSTTPVDS---NSPVVTSTAVSSSPTPAEGTSIAISTPSEGS 1513 Query: 556 RHIQGIQPAPISTQGIQPAPIG----TPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQ 611 + I P+ST + + I TP + P+ T S++P G M T Sbjct: 1514 TALTSI---PVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTS---MQTST 1567 Query: 612 PQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPS-- 669 EG T L +V + +N S P + T S AS++ A+GSS S Sbjct: 1568 -YSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTP 1626 Query: 670 -----ILRKKP------ATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQ 718 +L P A+ A S V +PV S E S+ + T T Sbjct: 1627 SEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYT 1686 Query: 719 QPPPTIPTMIAAASPPSQPAVA-LSTIP--GAVPITPPI------TTIAAAPPPSVTVGG 769 + + ++ +P + A++ LST P + P+T TT P+ T Sbjct: 1687 EGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSE 1746 Query: 770 SLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPG 829 + + PV V P+ P+ T+T + S A S+PTS L G Sbjct: 1747 GTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEG 1806 Query: 830 ASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKA 870 +P +++ E + T D S V + Sbjct: 1807 MTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSS 1847 Score = 107 bits (266), Expect = 8e-23 Identities = 224/943 (23%), Positives = 350/943 (37%), Gaps = 141/943 (14%) Query: 28 SSQQFPRLGAPSTGLSQAP-------SQIANSGSAGLINPAATVNDESGRDSEVSAREHM 80 +S Q ST L+ P S AN+ S I+ V + S +A Sbjct: 1561 TSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAE--- 1617 Query: 81 SSSSSLQSREEKQE-----PVVVRPY--PQVQMLST-----HHAVASATPVAVTAPPAHL 128 SS ++ + E PV P P+ LST + V ++T V+ + PA Sbjct: 1618 GSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEG 1677 Query: 129 TPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPP---KVPGQVTVTMESSIPQASA 185 T +++EG P T+ + P+A + STLS P P + SS + Sbjct: 1678 TSMPTSTYTEG-RTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEG 1736 Query: 186 IPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIG--------ASHLPRGAAAA 237 + + +G ++T +S S P+ A+ P A Sbjct: 1737 TSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGT 1796 Query: 238 AVMSSSKVTTVLRPTSQLPNAAT--AQPAVQHIIHQPIQSRPPVTTSNAI---PPAVVAT 292 ++ +S+ ++ + P + P + T A + P+ S PV TS A+ P T Sbjct: 1797 SIPTST-LSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGT 1855 Query: 293 VSATRAQS---------PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTT 343 AT S PV TTT A + + LS P + + + D ++ Sbjct: 1856 SIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSS 1915 Query: 344 RITLPSHPALGTP-------------KQQLHTMAQKTIFSTGTPVAA---ATVAPILATN 387 T S P G P +++T++ T+ T TPV A+ +P A Sbjct: 1916 MPT--STPREGRPPLTSIPVSTTTVASSEINTLST-TLADTRTPVTTYSQASSSPTTADG 1972 Query: 388 T-IPS-ATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTS--P 443 T +P+ A + GS T P ST + ++ + + T V TS T+ Sbjct: 1973 TSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGT 2032 Query: 444 RIQPDYPAERSSLI---PIS--------GHRASPNPVAMETRSDNRP----SVPVQFQYF 488 IQ P+ER++ + P+S G+ S PV +T+ N S + Sbjct: 2033 SIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSM 2092 Query: 489 LPTYPPSAYPLAAH---TYTPITS-SVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNP 544 + P PL + TP+ S ST+ PV + NS + T V +S + Sbjct: 2093 TISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDS---NSPVITSTEVS-SSPIPTEG 2148 Query: 545 MQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHS----ATPINTQ 600 + T S R + P+ST + + I T P T +S ++P ++ Sbjct: 2149 TSMQTSTYSDRR--TPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSE 2206 Query: 601 GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAAT-TVVQTHSQSASTNA 659 G M T P EG T + V ++ SA P T T V T +++ S+ Sbjct: 2207 GTS---MPTSTPS-EGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPT 2262 Query: 660 PAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPT-AQ 718 A+G+S S L ++G P + I VS + T+S D T T A Sbjct: 2263 TAEGTSIPTSTL-----SEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEAS 2317 Query: 719 QPPPT-----IPTMIAAAS-------PPSQPAVA------LSTIPG--AVPITP------ 752 PPPT +PT ++ P S VA LST P + P+T Sbjct: 2318 SPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGS 2377 Query: 753 -PITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPS 811 P T + P S GS + + PV + V PV P+ T+T + S Sbjct: 2378 SPTTADDTSMPTSTYSEGS-TPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASS 2436 Query: 812 LALLANNLSMPTSDLPPGASP-RKKPRKQQHVISTEEGDMMET 853 A S+PTS G +P P V+S+E G + T Sbjct: 2437 SPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTT 2479 Score = 102 bits (255), Expect = 1e-21 Identities = 174/804 (21%), Positives = 286/804 (35%), Gaps = 96/804 (11%) Query: 103 QVQMLSTHHAVASATPVAVTAPPAHLT-PAVPLSFSEGLMKPPPKPTMPSRPIAPAPPST 161 Q Q LS H SA A ++ P + LS S P+ T + P Sbjct: 51 QCQQLSQHVRTGSAANTATGTTSTNVVEPRMYLSCSTN-----PEMTSIESSVTSDTPG- 104 Query: 162 LSLPPKVPGQVTVTMESSIPQASAIPVATI-SGQQGHPSNLHHIMTTNVQMSIIRSNAPG 220 +S P + T ES+ + P +T + P M+T + SI + A Sbjct: 105 VSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMA-- 162 Query: 221 PPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQL------PNAATAQPAVQHIIHQPIQ 274 + + LP A ++ ++T L ++Q P + T + P+ Sbjct: 163 ---FVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLT 219 Query: 275 SRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQR 334 S P T A A+ + +PV + A ++ + P+LS P + + Sbjct: 220 SMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPL-- 277 Query: 335 PAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVA---PILATNT-IP 390 TR+ L + + L T T +T PV +T A P A T IP Sbjct: 278 --------TRMPLSVMLVVSSEASTLST----TPAATNIPVITSTEASSSPTTAEGTSIP 325 Query: 391 SAT-TAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDY 449 ++T T GS T P ST+ T + T V TS + P + T+ Sbjct: 326 TSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLT 385 Query: 450 PAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITS 509 P++ S VA + + ++PV + F+ T + +S Sbjct: 386 STLSEGSTPLTNMPVSTILVA-SSEASTTSTIPVDSKTFVT------------TASEASS 432 Query: 510 SVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQ 569 S +T ++ P+ T T + V++T P+ + ST+ Sbjct: 433 SPTTAEDTSIATSTPSEGSTPLTSMPVSTT----PVASSEASNLSTTPVDSKTQVTTSTE 488 Query: 570 GIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATI 629 P P ++G +TP+ + + P+ + E T + D +T Sbjct: 489 ASSSPPTAEVNSMPTSTPSEG---STPLTSMSVSTMPVASS----EASTLSTTPVDTST- 540 Query: 630 VANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVS 689 P++ A+ ++TT T S T+ P++GS+P L P + SE + Sbjct: 541 ---PVTTSSEASSSSTTPEGT---SIPTSTPSEGSTP----LTNMPVSTRLVVSSEASTT 590 Query: 690 MATP------VTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTM-IAAASPPSQPAVALS 742 TP VT S E S+ + T T + TI +M ++ S A LS Sbjct: 591 STTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLS 650 Query: 743 TIPGAVPITPPITTIAAAPPPSVTVGGS----------LSSVLGPPVPEIKVKEEVEPMD 792 T P V P+TT A S T G+ + + PV V Sbjct: 651 TTP--VDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTL 708 Query: 793 IMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMME 852 PV P+ T+T + S A+ SMPTS G++P + ++++ E + Sbjct: 709 STTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLS 768 Query: 853 TNSTDDEKSTAKSLLVKAEKRKSP 876 T D T+ + E SP Sbjct: 769 TTPLD----TSTHITTSTEASCSP 788 Score = 99.4 bits (246), Expect = 2e-20 Identities = 183/848 (21%), Positives = 310/848 (36%), Gaps = 77/848 (9%) Query: 50 ANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLST 109 A++ SA ++ + V + S + E S +S S E P+ P + ++ Sbjct: 2237 ASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLS--EGTTPLTSIPVSHTLVANS 2294 Query: 110 HHAVASATPVAVTAPPAHLTPAV-PLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKV 168 + S TPV P T A P +EG P + + P+ P ST V Sbjct: 2295 EVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTM----V 2350 Query: 169 PGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGAS 228 T T+ S+ P ++ PV T S P+ T++ S S P + S Sbjct: 2351 ASFETSTL-STTPADTSTPVTTYSQAGSSPTTADD---TSMPTSTY-SEGSTPLTSVPVS 2405 Query: 229 HLPRGAAAAAVMSSSKV--TTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIP 286 +P ++ A+ S++ V +T + +++ ++ T P + P+ + Sbjct: 2406 TMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVST 2465 Query: 287 PAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRIT 346 VV++ + T + +PV T+T + A S PT + + I ++ + T I Sbjct: 2466 TPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTA----EDIVVPISTASEGSTLLTSIP 2521 Query: 347 LPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTS 406 + + P L T T + +PV +T AT+ ++ + S P Sbjct: 2522 VSTTPVASPEASTLST----TPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLR 2577 Query: 407 TIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASP 466 ++ T P SS A+ ++T+ PV +P TS + + +PIS +P Sbjct: 2578 SMPVSTKPLASSEASTLSTT--PVDTSIP---VTTSTETSSSPTTAKDTSMPIS----TP 2628 Query: 467 NPVAMETRSDNRPSVPVQFQ--YFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAP 524 + V+ S ++PV L T P L T T +SS +T + P Sbjct: 2629 SEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVT-TSTGTSSSPTTAEGSSMPTSTP 2687 Query: 525 NSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPG-IQP 583 T T + V++T+ N + P+ T P+ T Sbjct: 2688 GERSTPLTNILVSTTLLAN------------SEASTLSTTPVDTS----TPVTTSAEASS 2731 Query: 584 APLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPA 643 +P +G + G P P + A ++ A + P++ A+ + Sbjct: 2732 SPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSS 2791 Query: 644 ATTVVQTHSQSASTNAPAQGSSPRPS--ILRKKPATDGAKPKSEIHVSMATPVTVSMETV 701 TT T S T+ P++ S+P S + A+ A S V +TPVT S + Sbjct: 2792 PTTAEVT---SMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKAS 2848 Query: 702 SNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPP--SQPAVALSTIPGAVPITPPITTIAA 759 S+ + I VP + T+ T I ++ P S A LST P V + P+TT Sbjct: 2849 SSPTTAE-GIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTP--VDTSIPVTTSTE 2905 Query: 760 APPPSVTVGG-----SLSSVLGPPVPEIKVK------EEVEPMDIMRPVSAVPPLATNTV 808 T G S S + P+ I V E + PV P+ T+ Sbjct: 2906 GSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLS-TTPVDTRTPVTTSAE 2964 Query: 809 SPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLV 868 + S A SMP S +P +++ E + D T+ + Sbjct: 2965 ASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPAD----TSTPVTT 3020 Query: 869 KAEKRKSP 876 E SP Sbjct: 3021 STEASSSP 3028 Score = 83.6 bits (205), Expect = 9e-16 Identities = 150/739 (20%), Positives = 262/739 (35%), Gaps = 92/739 (12%) Query: 72 SEVSAREHMSSSSSL--QSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAP----- 124 +E S+ ++ +SL + E P+ + P + S+ + S TPV + P Sbjct: 3434 TEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSS 3493 Query: 125 PAHLTP------AVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMES 178 P + +P ++P S + P + + P+A + STLS P V VT S Sbjct: 3494 PTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTP-VDSNTFVTSSS 3552 Query: 179 ---SIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAA 235 S P + +S S+L ++ ++ ++ ++ P P Sbjct: 3553 QASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTP------------- 3599 Query: 236 AAAVMSSSKVTTVLRPTSQL--PNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATV 293 +V S+ VTT + S P T + + P+ P TTS I A A+ Sbjct: 3600 --SVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTAST 3657 Query: 294 SATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPAL 353 +PVIT+T ++ T+ I P + + S TTR+T L Sbjct: 3658 LPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVS---TTRVTSSEGSTL 3714 Query: 354 GTPKQQLHTMA-------------QKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSH 400 TP T T S P+ +T+ + +T P S + Sbjct: 3715 STPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTP 3774 Query: 401 TQAPTSTIVTMTVPSH--SSHATAVTTSNIPVAKVVPQQITHTSPRIQPDY---PAERSS 455 + T ++MT S SS T T+ +P++ + T+ I P P+E S+ Sbjct: 3775 SIPSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEAST 3834 Query: 456 LIPISGHRASPNPVAMETRSDNRPSVPVQFQY-------------FLPTYPPSAYPLAAH 502 L G ++P + + S + P+ + + T P+++P A+ Sbjct: 3835 LSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASI 3894 Query: 503 TYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQ 562 TP + +T +A P + V V T P + + ++ Sbjct: 3895 ASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVI-TEGSTPGTTIFIPST--------- 3944 Query: 563 PAPISTQGIQPAPIG---TPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTS 619 P ST + PA G TP I L T S++ + T++ T+ Sbjct: 3945 PVTSSTADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFST------TKEFTTPAMTT 3998 Query: 620 AVVLA--DGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPAT 677 A L +T + P + +A+T+ T + ST+ + +P R T Sbjct: 3999 AAPLTYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTIT 4058 Query: 678 DGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQP 737 P + +TP T S + + T+ + PT+ A P + Sbjct: 4059 SHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTTTAVPTN-- 4116 Query: 738 AVALSTIPGAVPITPPITT 756 + + P + P P TT Sbjct: 4117 -TTIKSNPTSTPTVPRTTT 4134 Score = 60.1 bits (144), Expect = 1e-08 Identities = 105/474 (22%), Positives = 180/474 (37%), Gaps = 67/474 (14%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVV 97 P T + + +++ +S + L P+ + ++ E +SSS++L S + Sbjct: 3695 PLTTMPVSTTRVTSSEGSTLSTPSVVTSTPV-----TTSTEAISSSATLDSTT-----MS 3744 Query: 98 VRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSF--------SEGLMKPPPKPTM 149 V ++ L T V S TPV T P TP++P + SEG P Sbjct: 3745 VSMPMEISTLGTTILV-STTPV--TRFPESSTPSIPSVYTSMSMTTASEGSSSPTTLEGT 3801 Query: 150 PSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIP--------VATISGQQGHPSNL 201 + P++ + L + ++V S S P +T +G P+ + Sbjct: 3802 TTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKAGSFSIPAEV 3861 Query: 202 HHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATA 261 T +++SI + + ++ LP A++ S+ + T T A+T Sbjct: 3862 -----TTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTP 3916 Query: 262 QPAVQHIIHQPIQSR------------PPVTTSNA-IPPAVVATVSATRAQSPVITTTAA 308 V I + + PVT+S A + PA VS +PVIT+T Sbjct: 3917 TIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVS-----TPVITSTEL 3971 Query: 309 HATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTI 368 + ++ S T S A T T PS P T + T A T+ Sbjct: 3972 NTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPR--TTSRGCTTSAS-TL 4028 Query: 369 FSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNI 428 +T TP + +V T + S+ + SHT PT P+HSS + S+ Sbjct: 4029 SATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFP------PAHSSTPPTTSASS- 4081 Query: 429 PVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVP 482 V P+ +T + R + P+ R++ P A P +++ + P+VP Sbjct: 4082 --TTVNPEAVTTMTTRTK---PSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVP 4130 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 120 bits (302), Expect = 5e-27 Identities = 178/792 (22%), Positives = 261/792 (32%), Gaps = 81/792 (10%) Query: 95 PVVVRPYPQVQMLSTHHAVASATP--VAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSR 152 P P P +T + +P T PP TP+ P++ + PP T PS Sbjct: 1401 PPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTT----TPPPTTTPSP 1456 Query: 153 PIA----PAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTN 208 PI+ P P +T S P P T T + P T P I Sbjct: 1457 PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPS----PPTTTPITPPA 1512 Query: 209 VQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRP---TSQLPNAATAQPAV 265 ++ + P PP + P S TT + P T+ LP T P Sbjct: 1513 STTTLPPTTTPSPPTTTTTTPPP------TTTPSPPTTTPITPPTSTTTLPPTTTPSPPP 1566 Query: 266 QHIIHQPIQSRP-PVTTSNAIPPAVVATV-SATRAQSPVITTTAAHATDSALSRPTLSIQ 323 P + P P TT+ PP + T T SP TTT + S PT + Sbjct: 1567 TTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1626 Query: 324 HPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPI 383 PP++ ++ T T P P TP T I +T TP T + Sbjct: 1627 TPPTSTTTLPPTTTPSPPPTTTTTP--PPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSP 1684 Query: 384 LATNTIPSATTAGSVSHTQAPTSTIVTMTVPSH-SSHATAVTTSNIPVAKVVPQQITHTS 442 + T P TT + S T P+S I T T PS ++ + TT P P T T Sbjct: 1685 ITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTM 1744 Query: 443 PRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPV-QFQYFLPTYPPSAYPLAA 501 + P + + P+ P T + P VP+ + +L + P+ + Sbjct: 1745 TTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGG 1804 Query: 502 HT-----------YTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQL--M 548 T I+ + P+ G+ + P + M Sbjct: 1805 DTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGL-ICKNEDQKPGGVIPM 1863 Query: 549 TVDASHARHIQ----GIQPAPISTQGIQ-PAPIGTPGI--------QPAPLGTQGIHSAT 595 ++ ++Q QP ++T + P P T I P P GTQ + T Sbjct: 1864 AFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQ-TPTTT 1922 Query: 596 PINTQGL---QPAPMGTQQP--QPEGKTSAVVLADGATIVANPISNPFSAAPAAT-TVVQ 649 PI T P P GTQ P P T+ V T P + P + T T Sbjct: 1923 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 1982 Query: 650 THSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQP 709 T +Q+ +T ++ P+ T P + TP +T + Sbjct: 1983 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2042 Query: 710 TIAVP---PTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPP---- 762 T P PT Q P T P P+ T P T PITT P Sbjct: 2043 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTP 2097 Query: 763 -----PSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLAN 817 P+ T + ++V P P P+ V+ P T T +P+ + Sbjct: 2098 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITT 2156 Query: 818 NLSMPTSDLPPG 829 ++ + P G Sbjct: 2157 TTTVTPTPTPTG 2168 Score = 112 bits (280), Expect = 2e-24 Identities = 167/757 (22%), Positives = 239/757 (31%), Gaps = 57/757 (7%) Query: 115 SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP-PSTLSLPPKVPGQVT 173 + T T P T P G P P + + P P P+ P P T Sbjct: 3547 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3606 Query: 174 VTME-------SSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIG 226 T+ + P + I T P+ TT + + + P P Sbjct: 3607 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3666 Query: 227 ASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIP 286 + P + + T T+ + T P Q + P+TT+ + Sbjct: 3667 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVT 3725 Query: 287 PAVVATVSATRAQSPVITTTAAHATDSALSRPT--------LSIQHPPSAAISIQRPAQS 338 P T + T +P+ TTT T + T + P Q P + Sbjct: 3726 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3785 Query: 339 RDVTTRITLPSHPALGTPKQQ---LHTMAQKTIFSTGTPVAAATVAPILATNTI-PSATT 394 TT P+ GT + T T T T T PI T T+ P+ T Sbjct: 3786 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3845 Query: 395 AGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERS 454 G+ + T P +T T+T + TT+ I V T T + P + Sbjct: 3846 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3905 Query: 455 SLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHT--YTPITSSVS 512 + + +P P T++ + T P+ P T TPIT++ + Sbjct: 3906 TTV-------TPTPTPTGTQTPTTTPITTT-----TTVTPTPTPTGTQTPTTTPITTTTT 3953 Query: 513 -TIRQYPVSAQAPNSA-ITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQG 570 T P Q P + IT T V T Q T P P TQ Sbjct: 3954 VTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQT 4011 Query: 571 IQPAPIGTPGI---QPAPLGTQGIHSATPINTQGL---QPAPMGTQQPQ--PEGKTSAVV 622 PI T P P GTQ + TPI T P P GTQ P P T+ V Sbjct: 4012 PTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4070 Query: 623 LADGATIVANPISNPFSAAPAAT-TVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAK 681 T P + P + T T T +Q+ +T ++ P+ T Sbjct: 4071 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4130 Query: 682 PKSEIHVSMATPVTVSMETVSNQNNDQPTIAVP---PTAQQPPPTIPTMIAAASPPSQPA 738 P + TP +T + T P PT Q P T P P+ Sbjct: 4131 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4190 Query: 739 VALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVS 798 T P T PI + + PP + S P+ E P I + Sbjct: 4191 TGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTST 4250 Query: 799 AVPPLATNTVSPSLALLANNLSMP--TSDLPPGASPR 833 A P T +P+ + LS P T+ PPG R Sbjct: 4251 APPSTPT---APTTTSGGHTLSPPPSTTTSPPGTPTR 4284 Score = 111 bits (278), Expect = 3e-24 Identities = 158/700 (22%), Positives = 232/700 (33%), Gaps = 59/700 (8%) Query: 115 SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP-PSTLSLPPKVPGQVT 173 + T T P T P G P P + + P P P+ P P T Sbjct: 3639 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3698 Query: 174 VTME-------SSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIG 226 T+ + P + I T P+ TT + + + P P Sbjct: 3699 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3758 Query: 227 ASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIP 286 + P + + T T+ + T P Q + P+TT+ + Sbjct: 3759 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVT 3817 Query: 287 PAVVATVSATRAQSPVITTTAAHATDSALSRPT--------LSIQHPPSAAISIQRPAQS 338 P T + T +P+ TTT T + T + P Q P + Sbjct: 3818 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3877 Query: 339 RDVTTRITLPSHPALGTPKQQ---LHTMAQKTIFSTGTPVAAATVAPILATNTI-PSATT 394 TT P+ GT + T T T T T PI T T+ P+ T Sbjct: 3878 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3937 Query: 395 AGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERS 454 G+ + T P +T T+T + TT+ I V T T + P + Sbjct: 3938 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3997 Query: 455 SLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHT--YTPITSSVS 512 + + +P P T++ + T P+ P T TPIT++ + Sbjct: 3998 TTV-------TPTPTPTGTQTPTTTPITTT-----TTVTPTPTPTGTQTPTTTPITTTTT 4045 Query: 513 -TIRQYPVSAQAPNSA-ITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQG 570 T P Q P + IT T V T Q T P P TQ Sbjct: 4046 VTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQT 4103 Query: 571 IQPAPIGTPGI---QPAPLGTQGIHSATPINTQGL---QPAPMGTQQPQ--PEGKTSAVV 622 PI T P P GTQ + TPI T P P GTQ P P T+ V Sbjct: 4104 PTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4162 Query: 623 LADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRP--SILRKKPATDGA 680 T P + P + TTV T + + + P +S P + P + + Sbjct: 4163 PTPTPTGTQTPTTTPITTT---TTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESS 4219 Query: 681 KPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVA 740 P++ S ++P+T S +S P I + TA PT PT + S P Sbjct: 4220 TPQTSR--STSSPLTESTTLLSTL---PPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPST 4274 Query: 741 LSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVP 780 ++ PG P T ++AP PS + S+ P P Sbjct: 4275 TTSPPGT-PTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTP 4313 Score = 110 bits (276), Expect = 5e-24 Identities = 175/784 (22%), Positives = 248/784 (31%), Gaps = 66/784 (8%) Query: 115 SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP-PSTLSLPPKVPGQVT 173 + T T P T P G P P + + P P P+ P P T Sbjct: 3478 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3537 Query: 174 VTME-------SSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIG 226 T+ + P + I T P+ TT + + + P P Sbjct: 3538 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3597 Query: 227 ASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIP 286 + P + + T T+ + T P Q + P+TT+ + Sbjct: 3598 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVT 3656 Query: 287 PAVVATVSATRAQSPVITTTAAHATDSALSRPT--------LSIQHPPSAAISIQRPAQS 338 P T + T +P+ TTT T + T + P Q P + Sbjct: 3657 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3716 Query: 339 RDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSV 398 TT P+ GT Q T T +T TP T T I + TT V Sbjct: 3717 PITTTTTVTPTPTPTGT---QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT---V 3770 Query: 399 SHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIP 458 + T PT T T P ++ T VT + P P T+ P + P Sbjct: 3771 TPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3828 Query: 459 IS---GHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAH--TYTPITSSVS- 512 + + P T + + P+ T P+ P T TPIT++ + Sbjct: 3829 TTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPTPTGTQTPTTTPITTTTTV 3885 Query: 513 TIRQYPVSAQAPNSA-ITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGI 571 T P Q P + IT T V T Q T P P TQ Sbjct: 3886 TPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQTP 3943 Query: 572 QPAPIGTPGI---QPAPLGTQGIHSATPINTQGL---QPAPMGTQQP--QPEGKTSAVVL 623 PI T P P GTQ + TPI T P P GTQ P P T+ V Sbjct: 3944 TTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4002 Query: 624 ADGATIVANPISNPFSAAPAAT-TVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKP 682 T P + P + T T T +Q+ +T ++ P+ T P Sbjct: 4003 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4062 Query: 683 KSEIHVSMATPVTVSMETVSNQNNDQPTIAVP---PTAQQPPPTIPTMIAAASPPSQPAV 739 + TP +T + T P PT Q P T P P+ Sbjct: 4063 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4122 Query: 740 ALSTIPGAVPITPPITTIAAAPP---------PSVTVGGSLSSVLGPPVPEIKVKEEVEP 790 T P T PITT P P+ T + ++V P P P Sbjct: 4123 GTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4177 Query: 791 MDIMRPVSAVP-PLATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGD 849 + V+ P P T T P+ A + TS+ PP +S + R + TE Sbjct: 4178 ITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPL-TESTT 4236 Query: 850 MMET 853 ++ T Sbjct: 4237 LLST 4240 Score = 110 bits (275), Expect = 7e-24 Identities = 146/677 (21%), Positives = 220/677 (32%), Gaps = 57/677 (8%) Query: 115 SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP-PSTLSLPPKVPGQVT 173 + T T P T P G P P + + P P P+ P P T Sbjct: 3662 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3721 Query: 174 VTME-------SSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIG 226 T+ + P + I T P+ TT + + + P P Sbjct: 3722 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3781 Query: 227 ASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIP 286 + P + + T T+ + T P Q + P+TT+ + Sbjct: 3782 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVT 3840 Query: 287 PAVVATVSATRAQSPVITTTAAHATDSALSRPT--------LSIQHPPSAAISIQRPAQS 338 P T + T +P+ TTT T + T + P Q P + Sbjct: 3841 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3900 Query: 339 RDVTTRITLPSHPALGTPKQQ---LHTMAQKTIFSTGTPVAAATVAPILATNTI-PSATT 394 TT P+ GT + T T T T T PI T T+ P+ T Sbjct: 3901 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3960 Query: 395 AGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERS 454 G+ + T P +T T+T + TT+ I V T T + P + Sbjct: 3961 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 4020 Query: 455 SLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHT--YTPITSSVS 512 + + +P P T++ + T P+ P T TPIT++ + Sbjct: 4021 TTV-------TPTPTPTGTQTPTTTPITTT-----TTVTPTPTPTGTQTPTTTPITTTTT 4068 Query: 513 -TIRQYPVSAQAPNSA-ITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQG 570 T P Q P + IT T V T Q T P P TQ Sbjct: 4069 VTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQT 4126 Query: 571 IQPAPIGTPGI---QPAPLGTQGIHSATPINTQGL---QPAPMGTQQPQPEGKTSAVVLA 624 PI T P P GTQ + TPI T P P GTQ P + + Sbjct: 4127 PTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTP------TTTPIT 4179 Query: 625 DGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKS 684 T+ P P T ++ ++N P + S+P+ S P T+ S Sbjct: 4180 TTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLS 4239 Query: 685 EI--HVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIP---TMIAAASPPSQPAV 739 + + M + S T + T++ PP+ PP P T ++S P+ V Sbjct: 4240 TLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTV 4299 Query: 740 ALSTIPGAVPITPPITT 756 +T P P++T Sbjct: 4300 QTTTTSAWTPTPTPLST 4316 Score = 108 bits (271), Expect = 2e-23 Identities = 164/760 (21%), Positives = 239/760 (31%), Gaps = 67/760 (8%) Query: 115 SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP-PSTLSLPPKVPGQVT 173 + T T P T P G P P + + P P P+ P P T Sbjct: 1914 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 1973 Query: 174 VTME-------SSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIG 226 T+ + P + I T P+ TT + + + P P Sbjct: 1974 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2033 Query: 227 ASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIP 286 + P + + T T+ + T P Q + P+TT+ + Sbjct: 2034 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVT 2092 Query: 287 PAVVATVSATRAQSPVITTTAAHATDSALSR--------PTLSIQHPPSAAISIQRPAQS 338 P T + T +P+ TTT T + T + P Q P + Sbjct: 2093 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2152 Query: 339 RDVTTRITLPSHPALGT---PKQQLHTMAQKTIFSTGTPVAAATVAPILATNTI-PSATT 394 TT P+ GT + T T T T T PI T T+ P+ T Sbjct: 2153 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2212 Query: 395 AGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERS 454 G+ + T P +T T+T + TT+ I V T T + P + Sbjct: 2213 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2272 Query: 455 SLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAH--TYTPITSSVS 512 + + +P P T++ + T P+ P T TPIT++ + Sbjct: 2273 TTV-------TPTPTPTGTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTT 2320 Query: 513 -TIRQYPVSAQAPNSA-ITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQG 570 T P Q P + IT T V T Q T P P TQ Sbjct: 2321 VTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQT 2378 Query: 571 IQPAPIGTPGI---QPAPLGTQGIHSATPINTQGL---QPAPMGTQQP--QPEGKTSAVV 622 PI T P P GTQ + TPI T P P GTQ P P T+ V Sbjct: 2379 PTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2437 Query: 623 LADGATIVANPISNPFSAAPAAT-TVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAK 681 T P + P + T T T +Q+ +T ++ P+ T Sbjct: 2438 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2497 Query: 682 PKSEIHVSMATPVTVSMETVSNQNNDQPTIAVP---PTAQQPPPTIPTMIAAASPPSQPA 738 P + TP +T + T P PT Q P T P P+ Sbjct: 2498 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2557 Query: 739 VALSTIPGAVPITPPITTIAAAPP---------PSVTVGGSLSSVLGPPVPEIKVKEEVE 789 T P T PITT P P+ T + ++V P P Sbjct: 2558 TGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2612 Query: 790 PMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPG 829 P+ V+ P T T +P+ + ++ + P G Sbjct: 2613 PITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTG 2651 Score = 107 bits (267), Expect = 6e-23 Identities = 163/753 (21%), Positives = 237/753 (31%), Gaps = 67/753 (8%) Query: 122 TAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP-PSTLSLPPKVPGQVTVTME--- 177 T P T P G P P + + P P P+ P P T T+ Sbjct: 1898 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1957 Query: 178 ----SSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRG 233 + P + I T P+ TT + + + P P + P Sbjct: 1958 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2017 Query: 234 AAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATV 293 + + T T+ + T P Q + P+TT+ + P T Sbjct: 2018 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTG 2076 Query: 294 SATRAQSPVITTTAAHATDSALSR--------PTLSIQHPPSAAISIQRPAQSRDVTTRI 345 + T +P+ TTT T + T + P Q P + TT Sbjct: 2077 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2136 Query: 346 TLPSHPALGT---PKQQLHTMAQKTIFSTGTPVAAATVAPILATNTI-PSATTAGSVSHT 401 P+ GT + T T T T T PI T T+ P+ T G+ + T Sbjct: 2137 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2196 Query: 402 QAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISG 461 P +T T+T + TT+ I V T T + P ++ + Sbjct: 2197 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV---- 2252 Query: 462 HRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAH--TYTPITSSVS-TIRQYP 518 +P P T++ + T P+ P T TPIT++ + T P Sbjct: 2253 ---TPTPTPTGTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2304 Query: 519 VSAQAPNSA-ITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIG 577 Q P + IT T V T Q T P P TQ PI Sbjct: 2305 TGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2362 Query: 578 TPGI---QPAPLGTQGIHSATPINTQGL---QPAPMGTQQP--QPEGKTSAVVLADGATI 629 T P P GTQ + TPI T P P GTQ P P T+ V T Sbjct: 2363 TTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2421 Query: 630 VANPISNPFSAAPAAT-TVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHV 688 P + P + T T T +Q+ +T ++ P+ T P + Sbjct: 2422 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2481 Query: 689 SMATPVTVSMETVSNQNNDQPTIAVP---PTAQQPPPTIPTMIAAASPPSQPAVALSTIP 745 TP +T + T P PT Q P T P P+ T Sbjct: 2482 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-- 2539 Query: 746 GAVPITPPITTIAAAPP---------PSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRP 796 P T PITT P P+ T + ++V P P P+ Sbjct: 2540 ---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2596 Query: 797 VSAVPPLATNTVSPSLALLANNLSMPTSDLPPG 829 V+ P T T +P+ + ++ + P G Sbjct: 2597 VTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTG 2628 Score = 104 bits (259), Expect = 5e-22 Identities = 166/759 (21%), Positives = 237/759 (31%), Gaps = 65/759 (8%) Query: 115 SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP-PSTLSLPPKVPGQVT 173 + T T P T P G P P + + P P P+ P P T Sbjct: 2167 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2226 Query: 174 VTME-------SSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIG 226 T+ + P + I T P+ TT + + + P P Sbjct: 2227 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2286 Query: 227 ASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIP 286 + P + + T T+ + T P Q + P+TT+ + Sbjct: 2287 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVT 2345 Query: 287 PAVVATVSATRAQSPVITTTAAHATDSALSRPT--------LSIQHPPSAAISIQRPAQS 338 P T + T +P+ TTT T + T + P Q P + Sbjct: 2346 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2405 Query: 339 RDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSV 398 TT P+ GT Q T T +T TP T T I + TT V Sbjct: 2406 PITTTTTVTPTPTPTGT---QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT---V 2459 Query: 399 SHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIP 458 + T PT T T P ++ T VT + P P T+ P + P Sbjct: 2460 TPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2517 Query: 459 IS---GHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAH--TYTPITSSVS- 512 + + P T + + P+ T P+ P T TPIT++ + Sbjct: 2518 TTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPTPTGTQTPTTTPITTTTTV 2574 Query: 513 TIRQYPVSAQAPNSA-ITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGI 571 T P Q P + IT T V T Q T P P TQ Sbjct: 2575 TPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQTP 2632 Query: 572 QPAPIGTPGI---QPAPLGTQGIHSATPINTQGL---QPAPMGTQQP--QPEGKTSAVVL 623 PI T P P GTQ + TPI T P P GTQ P P T+ V Sbjct: 2633 TTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2691 Query: 624 ADGATIVANPISNPFSAAPAAT-TVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKP 682 T P + P + T T T +Q+ +T ++ P+ T P Sbjct: 2692 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2751 Query: 683 KSEIHVSMATPVTVSMETVSNQNNDQPTIAVP---PTAQQPPPTIPTMIAAASPPSQPAV 739 + TP +T + T P PT Q P T P P+ Sbjct: 2752 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2811 Query: 740 ALSTIPGAVPITPPITTIAAAPP---------PSVTVGGSLSSVLGPPVPEIKVKEEVEP 790 T P T PITT P P+ T + ++V P P P Sbjct: 2812 GTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2866 Query: 791 MDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPG 829 + V+ P T T +P+ + ++ + P G Sbjct: 2867 ITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTG 2904 Score = 104 bits (259), Expect = 5e-22 Identities = 166/759 (21%), Positives = 237/759 (31%), Gaps = 65/759 (8%) Query: 115 SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP-PSTLSLPPKVPGQVT 173 + T T P T P G P P + + P P P+ P P T Sbjct: 2604 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2663 Query: 174 VTME-------SSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIG 226 T+ + P + I T P+ TT + + + P P Sbjct: 2664 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2723 Query: 227 ASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIP 286 + P + + T T+ + T P Q + P+TT+ + Sbjct: 2724 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVT 2782 Query: 287 PAVVATVSATRAQSPVITTTAAHATDSALSRPT--------LSIQHPPSAAISIQRPAQS 338 P T + T +P+ TTT T + T + P Q P + Sbjct: 2783 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2842 Query: 339 RDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSV 398 TT P+ GT Q T T +T TP T T I + TT V Sbjct: 2843 PITTTTTVTPTPTPTGT---QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT---V 2896 Query: 399 SHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIP 458 + T PT T T P ++ T VT + P P T+ P + P Sbjct: 2897 TPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2954 Query: 459 IS---GHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAH--TYTPITSSVS- 512 + + P T + + P+ T P+ P T TPIT++ + Sbjct: 2955 TTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPTPTGTQTPTTTPITTTTTV 3011 Query: 513 TIRQYPVSAQAPNSA-ITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGI 571 T P Q P + IT T V T Q T P P TQ Sbjct: 3012 TPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQTP 3069 Query: 572 QPAPIGTPGI---QPAPLGTQGIHSATPINTQGL---QPAPMGTQQP--QPEGKTSAVVL 623 PI T P P GTQ + TPI T P P GTQ P P T+ V Sbjct: 3070 TTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3128 Query: 624 ADGATIVANPISNPFSAAPAAT-TVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKP 682 T P + P + T T T +Q+ +T ++ P+ T P Sbjct: 3129 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3188 Query: 683 KSEIHVSMATPVTVSMETVSNQNNDQPTIAVP---PTAQQPPPTIPTMIAAASPPSQPAV 739 + TP +T + T P PT Q P T P P+ Sbjct: 3189 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3248 Query: 740 ALSTIPGAVPITPPITTIAAAPP---------PSVTVGGSLSSVLGPPVPEIKVKEEVEP 790 T P T PITT P P+ T + ++V P P P Sbjct: 3249 GTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3303 Query: 791 MDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPG 829 + V+ P T T +P+ + ++ + P G Sbjct: 3304 ITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTG 3341 Score = 104 bits (259), Expect = 5e-22 Identities = 166/759 (21%), Positives = 237/759 (31%), Gaps = 65/759 (8%) Query: 115 SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP-PSTLSLPPKVPGQVT 173 + T T P T P G P P + + P P P+ P P T Sbjct: 3041 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3100 Query: 174 VTME-------SSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIG 226 T+ + P + I T P+ TT + + + P P Sbjct: 3101 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3160 Query: 227 ASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIP 286 + P + + T T+ + T P Q + P+TT+ + Sbjct: 3161 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVT 3219 Query: 287 PAVVATVSATRAQSPVITTTAAHATDSALSRPT--------LSIQHPPSAAISIQRPAQS 338 P T + T +P+ TTT T + T + P Q P + Sbjct: 3220 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3279 Query: 339 RDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSV 398 TT P+ GT Q T T +T TP T T I + TT V Sbjct: 3280 PITTTTTVTPTPTPTGT---QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT---V 3333 Query: 399 SHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIP 458 + T PT T T P ++ T VT + P P T+ P + P Sbjct: 3334 TPTPTPTGTQTPTTTPITTT--TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3391 Query: 459 IS---GHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAH--TYTPITSSVS- 512 + + P T + + P+ T P+ P T TPIT++ + Sbjct: 3392 TTTPITTTTTVTPTPTPTGTQTPTTTPIT---TTTTVTPTPTPTGTQTPTTTPITTTTTV 3448 Query: 513 TIRQYPVSAQAPNSA-ITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGI 571 T P Q P + IT T V T Q T P P TQ Sbjct: 3449 TPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGTQTP 3506 Query: 572 QPAPIGTPGI---QPAPLGTQGIHSATPINTQGL---QPAPMGTQQP--QPEGKTSAVVL 623 PI T P P GTQ + TPI T P P GTQ P P T+ V Sbjct: 3507 TTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3565 Query: 624 ADGATIVANPISNPFSAAPAAT-TVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKP 682 T P + P + T T T +Q+ +T ++ P+ T P Sbjct: 3566 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3625 Query: 683 KSEIHVSMATPVTVSMETVSNQNNDQPTIAVP---PTAQQPPPTIPTMIAAASPPSQPAV 739 + TP +T + T P PT Q P T P P+ Sbjct: 3626 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3685 Query: 740 ALSTIPGAVPITPPITTIAAAPP---------PSVTVGGSLSSVLGPPVPEIKVKEEVEP 790 T P T PITT P P+ T + ++V P P P Sbjct: 3686 GTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3740 Query: 791 MDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPG 829 + V+ P T T +P+ + ++ + P G Sbjct: 3741 ITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTG 3778 Score = 96.7 bits (239), Expect = 1e-19 Identities = 173/787 (21%), Positives = 251/787 (31%), Gaps = 101/787 (12%) Query: 95 PVVVRPYPQVQMLSTHHAVAS-ATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRP 153 P+ P P ++T + ++P+ T P+ T P + P P+ P+ Sbjct: 1684 PITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTT 1743 Query: 154 IAPAPPSTLS-------LPPKVPGQVTVTMESSIPQASAIPVATISG--QQGHPSNLHHI 204 + PP+T S LPP + ++ P +P+ +G G P N H Sbjct: 1744 MTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKP-NFHKP 1802 Query: 205 MTTNVQMSIIRSNAPGPPLHIGAS-----HLPRGAAAAAVMSSSKVTTVLRPTSQLPNAA 259 + + PG +I +P G V+ V + + Q P Sbjct: 1803 GGDTELIGDVCG--PGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGV 1860 Query: 260 TAQPAVQHI---------IHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHA 310 + + QP + TT N PP +P+ TTT Sbjct: 1861 IPMAFCLNYEINVQCCECVTQPT-TMTTTTTENPTPPTT----------TPITTTTTVTP 1909 Query: 311 TDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFS 370 T + PT Q P + TT P+ GT Q T T + Sbjct: 1910 TPT----PT-----------GTQTPTTTPITTTTTVTPTPTPTGT---QTPTTTPITTTT 1951 Query: 371 TGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPV 430 T TP T T I + TT V+ T PT T T P ++ T VT + P Sbjct: 1952 TVTPTPTPTGTQTPTTTPITTTTT---VTPTPTPTGTQTPTTTPITTT--TTVTPTPTPT 2006 Query: 431 AKVVPQQITHTSPRIQPDYPAERSSLIPIS---GHRASPNPVAMETRSDNRPSVPVQFQY 487 P T+ P + P + + P T + + P+ Sbjct: 2007 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT--- 2063 Query: 488 FLPTYPPSAYPLAAH--TYTPITSSVS-TIRQYPVSAQAPNSA-ITAQTGVGVASTVHLN 543 T P+ P T TPIT++ + T P Q P + IT T V T Sbjct: 2064 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--T 2121 Query: 544 PMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGI---QPAPLGTQGIHSATPINTQ 600 Q T P P TQ PI T P P GTQ + TPI T Sbjct: 2122 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTT 2180 Query: 601 GL---QPAPMGTQQP--QPEGKTSAVVLADGATIVANPISNPFSAAPAAT-TVVQTHSQS 654 P P GTQ P P T+ V T P + P + T T T +Q+ Sbjct: 2181 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2240 Query: 655 ASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVP 714 +T ++ P+ T P + TP +T + T P Sbjct: 2241 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2300 Query: 715 ---PTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPP--------- 762 PT Q P T P P+ T P T PITT P Sbjct: 2301 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-----PTTTPITTTTTVTPTPTPTGTQT 2355 Query: 763 PSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMP 822 P+ T + ++V P P P+ V+ P T T +P+ + ++ Sbjct: 2356 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVT 2414 Query: 823 TSDLPPG 829 + P G Sbjct: 2415 PTPTPTG 2421 Score = 96.7 bits (239), Expect = 1e-19 Identities = 142/642 (22%), Positives = 206/642 (32%), Gaps = 64/642 (9%) Query: 231 PRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQP------IQSRPPVTTSNA 284 P + +++ VT PT T + P + P+TT+ Sbjct: 1893 PTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 1952 Query: 285 IPPAVVATVSATRAQSPVITTTAAHATDSALSR--------PTLSIQHPPSAAISIQRPA 336 + P T + T +P+ TTT T + T + P Q P Sbjct: 1953 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2012 Query: 337 QSRDVTTRITLPSHPALGT---PKQQLHTMAQKTIFSTGTPVAAATVAPILATNTI-PSA 392 + TT P+ GT + T T T T T PI T T+ P+ Sbjct: 2013 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2072 Query: 393 TTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAE 452 T G+ + T P +T T+T + TT+ I V T T + P Sbjct: 2073 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2132 Query: 453 RSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAH--TYTPITSS 510 ++ + +P P T++ + T P+ P T TPIT++ Sbjct: 2133 TTTTV-------TPTPTPTGTQTPTTTPITT-----TTTVTPTPTPTGTQTPTTTPITTT 2180 Query: 511 VS-TIRQYPVSAQAPNSA-ITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPIST 568 + T P Q P + IT T V T Q T P P T Sbjct: 2181 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP--TGTQTPTTTPITTTTTVTPTPTPTGT 2238 Query: 569 QGIQPAPIGTPGI---QPAPLGTQGIHSATPINTQGL---QPAPMGTQQP--QPEGKTSA 620 Q PI T P P GTQ + TPI T P P GTQ P P T+ Sbjct: 2239 QTPTTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2297 Query: 621 VVLADGATIVANPISNPFSAAPAAT-TVVQTHSQSASTNAPAQGSSPRPSILRKKPATDG 679 V T P + P + T T T +Q+ +T ++ P+ T Sbjct: 2298 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2357 Query: 680 AKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVP---PTAQQPPPTIPTMIAAASPPSQ 736 P + TP +T + T P PT Q P T P P+ Sbjct: 2358 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2417 Query: 737 PAVALSTIPGAVPITPPITTIAAAPP---------PSVTVGGSLSSVLGPPVPEIKVKEE 787 T P T PITT P P+ T + ++V P P Sbjct: 2418 TPTGTQT-----PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2472 Query: 788 VEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPG 829 P+ V+ P T T +P+ + ++ + P G Sbjct: 2473 TTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTG 2513 Score = 87.4 bits (215), Expect = 6e-17 Identities = 108/413 (26%), Positives = 148/413 (35%), Gaps = 35/413 (8%) Query: 121 VTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSI 180 +T P T P S + P P+ P+ PP+T PP +T T Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPP-----ITTTTTPPP 1450 Query: 181 PQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM 240 + P++T + P+ TT + P PP + P Sbjct: 1451 TTTPSPPISTTTTPP--PTTTPSPPTTTPSPP---TTTPSPPTTTTTTPPP------TTT 1499 Query: 241 SSSKVTTVLRP---TSQLPNAATAQPAVQHIIHQPIQSRP-PVTTSNAIPPAVVATVSAT 296 S TT + P T+ LP T P P + P P TT+ PP T+ T Sbjct: 1500 PSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT 1559 Query: 297 RAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQS-RDVTTRITLPSHPALGT 355 SP TTT + S PT + PP+ + P + TT T P P T Sbjct: 1560 TTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTP--PPTTT 1617 Query: 356 PKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTV-P 414 P T +T P T +P T T P TT S T P+ I T T P Sbjct: 1618 PSPPTTTPITPPTSTTTLP-PTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPP 1676 Query: 415 SHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETR 474 ++ ++ +TT+ P +T SP P P ++ P S SP P M T Sbjct: 1677 PTTTPSSPITTTPSPPTTT----MTTPSPTTTPSSPI-TTTTTPSSTTTPSPPPTTMTTP 1731 Query: 475 S-DNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNS 526 S PS P LP S+ PL T TP+ S++ P S P + Sbjct: 1732 SPTTTPSPPTTTMTTLPPTTTSS-PL---TTTPLPPSITPPTFSPFSTTTPTT 1780 Score = 78.6 bits (192), Expect = 3e-14 Identities = 109/444 (24%), Positives = 153/444 (34%), Gaps = 81/444 (18%) Query: 316 SRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPV 375 S PT + PP++ ++ TT T P P TP + T T TP Sbjct: 1400 SPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTP--PPTTTPSPPITT--------TTTPP 1449 Query: 376 AAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVP 435 T +P ++T T P TT S T P+ T + P T TT+ P P Sbjct: 1450 PTTTPSPPISTTTTPPPTTTPSPP-TTTPSPPTTTPSPP------TTTTTTPPPTTTPSP 1502 Query: 436 QQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPS 495 T +P PA ++L P + +P+P T T PP+ Sbjct: 1503 PTTTPITP------PASTTTLPPTT----TPSPPTTTTT----------------TPPPT 1536 Query: 496 AYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQ----TGVGVASTVHLNPMQLMTVD 551 P + T TPIT ST P + +P T T +T +P + T Sbjct: 1537 TTP-SPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTT 1595 Query: 552 ASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPIN--TQGLQPAPMGT 609 P P +T P+P T P P T + TPI T P T Sbjct: 1596 -----------PPPTTT----PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTT 1640 Query: 610 QQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPS 669 P P T+ T +P + + P TT + + S+ S P + Sbjct: 1641 PSPPPTTTTTPP-----PTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTT 1695 Query: 670 ILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIA 729 + P T + P + T T S T + T P T PP T T + Sbjct: 1696 MTTPSPTTTPSSP-------ITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTL- 1747 Query: 730 AASPPSQPAVALSTIPGAVPITPP 753 PP+ + L+T P ITPP Sbjct: 1748 ---PPTTTSSPLTTTPLPPSITPP 1768 Score = 73.2 bits (178), Expect = 1e-12 Identities = 111/489 (22%), Positives = 159/489 (32%), Gaps = 69/489 (14%) Query: 115 SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP-PSTLSLPPKVPGQVT 173 + T T P T P G P P + + P P P+ P P T Sbjct: 3892 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3951 Query: 174 VTME-------SSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIG 226 T+ + P + I T P+ TT + + + P P Sbjct: 3952 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4011 Query: 227 ASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIP 286 + P + + T T+ + T P Q + P+TT+ + Sbjct: 4012 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVT 4070 Query: 287 PAVVATVSATRAQSPVITTTAAHATDSALSRPT--------LSIQHPPSAAISIQRPAQS 338 P T + T +P+ TTT T + T + P Q P + Sbjct: 4071 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4130 Query: 339 RDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSV 398 TT P+ GT Q T T +T TP T T I + TT V Sbjct: 4131 PITTTTTVTPTPTPTGT---QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT---V 4184 Query: 399 SHTQAPTSTIVTMTVPSHSSHA--TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSL 456 + T PT T P+H+S A +TTSN P PQ TS + E ++L Sbjct: 4185 TPTPTPTGT--QTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPL-----TESTTL 4237 Query: 457 IPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQ 516 + S P A+E S PS P T TS T+ Sbjct: 4238 L-------STLPPAIEMTSTAPPSTP--------------------TAPTTTSGGHTLSP 4270 Query: 517 YPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPI 576 P + +P T T G +S + +Q T A P P+ST P+ I Sbjct: 4271 PPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTP------TPTPLST----PSII 4320 Query: 577 GTPGIQPAP 585 T G++P P Sbjct: 4321 RTTGLRPYP 4329 Score = 72.0 bits (175), Expect = 3e-12 Identities = 89/382 (23%), Positives = 122/382 (31%), Gaps = 55/382 (14%) Query: 490 PTYPPSAYPLAAHTYTPIT--SSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQL 547 PT PS P + T P T S +T P P+ IT T +T Sbjct: 1402 PTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTT 1461 Query: 548 MTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPM 607 T + P+P +T P+P T P P T + TPI Sbjct: 1462 TTPPPTTTPSPPTTTPSPPTTT---PSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLP 1518 Query: 608 GTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPR 667 T P P T T P + P +P TT + T S +T P SP Sbjct: 1519 PTTTPSPPTTT---------TTTPPPTTTP---SPPTTTPI-TPPTSTTTLPPTTTPSPP 1565 Query: 668 PSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQP------- 720 P+ P T P + S T T + + + T PP P Sbjct: 1566 PTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1625 Query: 721 --PPTIPTMIAAASPPSQPAVALSTIPGAVPITPPIT-------TIAAAPPPSVTVGGSL 771 PPT T + + PS P +T P +PP T T PPP+ T + Sbjct: 1626 ITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPI 1685 Query: 772 SSVLGPP-----------VPEIKVKEEVEPMDIMR----PVSAVPPLATNTVSP------ 810 ++ PP P + P P + P T T SP Sbjct: 1686 TTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMT 1745 Query: 811 SLALLANNLSMPTSDLPPGASP 832 +L + + T+ LPP +P Sbjct: 1746 TLPPTTTSSPLTTTPLPPSITP 1767 Score = 57.4 bits (137), Expect = 7e-08 Identities = 48/211 (22%), Positives = 73/211 (34%), Gaps = 11/211 (5%) Query: 628 TIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIH 687 T + P + P + TT+ T + S T ++P P+ P T P Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTT---TTPPPTTTPSPPITTTTTPPPTTT 1453 Query: 688 VSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGA 747 S T + + + T + P T PP T T + PS P T P + Sbjct: 1454 PSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAS 1513 Query: 748 VPITPPI------TTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVP 801 PP TT PPP+ T ++ + PP + P P + Sbjct: 1514 TTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSP--PPTTTTT 1571 Query: 802 PLATNTVSPSLALLANNLSMPTSDLPPGASP 832 P T T SP + ++ T+ PP +P Sbjct: 1572 PPPTTTPSPPTTTTPSPPTITTTTPPPTTTP 1602 Score = 41.6 bits (96), Expect = 0.004 Identities = 36/147 (24%), Positives = 51/147 (34%), Gaps = 7/147 (4%) Query: 724 IPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGP-----P 778 I T + PS P + +T+P +PP TT PPP+ T +++ P P Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTT-TTPPPTTTPSPPITTTTTPPPTTTP 1454 Query: 779 VPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRK 838 P I P P + P T T SP T+ PP +P P Sbjct: 1455 SPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPP-TTTTTTPPPTTTPSPPTTTPITPPAS 1513 Query: 839 QQHVISTEEGDMMETNSTDDEKSTAKS 865 + T T +T +T S Sbjct: 1514 TTTLPPTTTPSPPTTTTTTPPPTTTPS 1540 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 116 bits (291), Expect = 1e-25 Identities = 182/872 (20%), Positives = 290/872 (33%), Gaps = 100/872 (11%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDES---GRDSEVSAREHMSSSSSLQSREEKQE 94 P++ S+ S N + T N ++ G++ SA+E S + Sbjct: 132 PNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTS 191 Query: 95 PVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPI 154 V+ +P P+ + +T A TP P TP P S + P + P+ P Sbjct: 192 KVLAKPTPKAE--TTTKGPALTTP----KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 245 Query: 155 APAPPSTLSLP--PKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMS 212 PAP +T S P PK P T + P T ++ P+ TT + + Sbjct: 246 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT---KEPAPTTTKSAPTTPKEPA 302 Query: 213 IIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQP 272 P P P+ A ++ K T P P P Sbjct: 303 PTTPKKPAPT-------TPKEPAP----TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 351 Query: 273 IQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISI 332 +P TT P + T + P TT A + S PT + + P+ S Sbjct: 352 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 411 Query: 333 QRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSA 392 + TT PA TPK+ T +K P AP P+ Sbjct: 412 PTTPKEPSPTT----TKEPAPTTPKEPAPTTPKKP-----APTTPKEPAPTTPKEPAPTT 462 Query: 393 TTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSP-RIQPDYPA 451 T + + + P T T P+ T T + A P++ T+P + P P Sbjct: 463 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL--APTTPEKPAPTTPEELAPTTPE 520 Query: 452 ERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSV 511 E + P +P A T + P+ P + P P P TP ++ Sbjct: 521 EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP 580 Query: 512 STIRQ-YPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQG 570 +T+++ P + + P P +L +PAP + +G Sbjct: 581 TTLKEPAPTTPKKP------------------APKELAPTTTKEPTSTTCDKPAPTTPKG 622 Query: 571 IQPA----PIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADG 626 P P T +PAP +G T +PAP ++P P K A G Sbjct: 623 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTL-----KEPAPTTPKKPAP--KELAPTTTKG 675 Query: 627 ATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEI 686 T + S PA TT +T + AP P P+ P T Sbjct: 676 PT-------STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS------- 721 Query: 687 HVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPG 746 ++TP T T +++ D+ T P + +P P A + P +P V + P Sbjct: 722 --EVSTPTTTKEPTTIHKSPDEST---PELSAEPTPK-----ALENSPKEPGVPTTKTPA 771 Query: 747 AVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATN 806 A P +TT A + + + P + E + + + + Sbjct: 772 AT--KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTST 829 Query: 807 TVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSL 866 T + L T+ L P + KK +++ E ET D + +K+ Sbjct: 830 TTQDTTPFKITTLK--TTTLAPKVTTTKKTITTTEIMNKPE----ETAKPKDRATNSKAT 883 Query: 867 LVKAEKRKSPPKEYIDEEGVRYVPVRPRPPIT 898 K +K PK+ + + +P R R P T Sbjct: 884 TPKPQKPTKAPKKPTSTKKPKTMP-RVRKPKT 914 Score = 75.5 bits (184), Expect = 2e-13 Identities = 112/489 (22%), Positives = 166/489 (33%), Gaps = 44/489 (8%) Query: 369 FSTGTPVAAATVAPILATNTIPSATTAGSVSHT-----QAPTSTIVTMTVPSHSSHATAV 423 F TP + T ++T+ P TTA ++ + TS ++TV ++ T Sbjct: 97 FKVTTPDTSTTQHNKVSTS--PKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKE 154 Query: 424 TTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPV 483 TT+ ++ T ++ Q L P S A P P A T + P Sbjct: 155 TTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK 214 Query: 484 QFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLN 543 + P P S TP + +TI+ P + + P A T A T Sbjct: 215 EPTPTTPKEPAST--------TPKEPTPTTIKSAPTTPKEP-----APTTTKSAPTTPKE 261 Query: 544 PMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGI-----QPAPLGTQGIHSATPIN 598 P T + + + PAP +T+ +PAP T +PAP + TP Sbjct: 262 PAPTTTKEPAPTTPKE---PAPTTTK--EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 316 Query: 599 ---TQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAA-PAATTVVQTHSQS 654 T +P P ++P P K A A P + PA TT + + Sbjct: 317 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 376 Query: 655 ASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVP 714 +P P P+ + P T + + TP S T P P Sbjct: 377 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 436 Query: 715 PTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITP----PITTIAAAPPPSVTVGGS 770 T ++P PT P A + P +PA + P P TP P T AP + + Sbjct: 437 TTPKKPAPTTPKE-PAPTTPKEPAPTTTKKP--APTTPKEPAPTTPKETAPTTPKKLTPT 493 Query: 771 LSSVLGPPVPE---IKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLP 827 L P PE EE+ P P P T + A PT+ Sbjct: 494 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 553 Query: 828 PGASPRKKP 836 P + K+P Sbjct: 554 PAPTTPKEP 562 Score = 48.1 bits (113), Expect = 4e-05 Identities = 128/598 (21%), Positives = 185/598 (30%), Gaps = 91/598 (15%) Query: 33 PRLGAPSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEK 92 P AP+T AP+ P T +E + +A + + + +E Sbjct: 495 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 554 Query: 93 QEPVVVRPYPQVQMLSTHHAVASATPVAVTAP-----PAHLTPA--VPLSFSEGLMKPP- 144 P P +T A TP TAP PA TP P + K P Sbjct: 555 APTTPKEPAP-----TTPKETAPTTPKG-TAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 608 Query: 145 -----------PKPTMPSRPIAPAPPSTLSLPPKVP-GQVTVTMESSIPQASAIPVATIS 192 PK T P+ P PAP + P P G T++ P P Sbjct: 609 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA---- 664 Query: 193 GQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRP- 251 P L T + AP P A P+ A + T P Sbjct: 665 -----PKELAPTTTKGPTSTTSDKPAPTTPKET-APTTPKEPAPTTPKKPAPTTPETPPP 718 Query: 252 -TSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAV--------VATVSATRAQSPV 302 TS++ T + IH+ P ++ P A+ V T A P Sbjct: 719 TTSEVSTPTTTKEPTT--IHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPE 776 Query: 303 ITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHT 362 +TTTA T R T P + + + TT T S T Q T Sbjct: 777 MTTTAKDKTTERDLRTT------PETTTAAPKMTKETATTTEKTTESK-ITATTTQVTST 829 Query: 363 MAQKTIFSTGTPVAAATVAPILATN--TIPSATTAGSVSHTQAP----TSTIVTMTVPSH 416 Q T T + T+AP + T TI + T P T++ T P Sbjct: 830 TTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK 889 Query: 417 SSHATAVTTSNI----------PVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASP 466 + A TS P P+++T T P + P + L + +P Sbjct: 890 PTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTP 949 Query: 467 NPVAMETRSDNR---------PSVPVQFQYFLPTYPPS-----AYPLAAHTYTPITSSVS 512 N +E + P + ++ F+P P P P+ S + Sbjct: 950 NSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDET 1009 Query: 513 TIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQ--PAPIST 568 I + + + T + G VA H M S AR I + P+PI T Sbjct: 1010 NI----CNGKPVDGLTTLRNGTLVAFRGHYFWMLSPFSPPSPARRITEVWGIPSPIDT 1063 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 116 bits (291), Expect = 1e-25 Identities = 182/872 (20%), Positives = 290/872 (33%), Gaps = 100/872 (11%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDES---GRDSEVSAREHMSSSSSLQSREEKQE 94 P++ S+ S N + T N ++ G++ SA+E S + Sbjct: 173 PNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTS 232 Query: 95 PVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPI 154 V+ +P P+ + +T A TP P TP P S + P + P+ P Sbjct: 233 KVLAKPTPKAE--TTTKGPALTTP----KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 286 Query: 155 APAPPSTLSLP--PKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMS 212 PAP +T S P PK P T + P T ++ P+ TT + + Sbjct: 287 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT---KEPAPTTTKSAPTTPKEPA 343 Query: 213 IIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQP 272 P P P+ A ++ K T P P P Sbjct: 344 PTTPKKPAPT-------TPKEPAP----TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 392 Query: 273 IQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISI 332 +P TT P + T + P TT A + S PT + + P+ S Sbjct: 393 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 452 Query: 333 QRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSA 392 + TT PA TPK+ T +K P AP P+ Sbjct: 453 PTTPKEPSPTT----TKEPAPTTPKEPAPTTPKKP-----APTTPKEPAPTTPKEPAPTT 503 Query: 393 TTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSP-RIQPDYPA 451 T + + + P T T P+ T T + A P++ T+P + P P Sbjct: 504 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL--APTTPEKPAPTTPEELAPTTPE 561 Query: 452 ERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSV 511 E + P +P A T + P+ P + P P P TP ++ Sbjct: 562 EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP 621 Query: 512 STIRQ-YPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQG 570 +T+++ P + + P P +L +PAP + +G Sbjct: 622 TTLKEPAPTTPKKP------------------APKELAPTTTKEPTSTTCDKPAPTTPKG 663 Query: 571 IQPA----PIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADG 626 P P T +PAP +G T +PAP ++P P K A G Sbjct: 664 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTL-----KEPAPTTPKKPAP--KELAPTTTKG 716 Query: 627 ATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEI 686 T + S PA TT +T + AP P P+ P T Sbjct: 717 PT-------STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS------- 762 Query: 687 HVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPG 746 ++TP T T +++ D+ T P + +P P A + P +P V + P Sbjct: 763 --EVSTPTTTKEPTTIHKSPDEST---PELSAEPTPK-----ALENSPKEPGVPTTKTPA 812 Query: 747 AVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATN 806 A P +TT A + + + P + E + + + + Sbjct: 813 AT--KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTST 870 Query: 807 TVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSL 866 T + L T+ L P + KK +++ E ET D + +K+ Sbjct: 871 TTQDTTPFKITTLK--TTTLAPKVTTTKKTITTTEIMNKPE----ETAKPKDRATNSKAT 924 Query: 867 LVKAEKRKSPPKEYIDEEGVRYVPVRPRPPIT 898 K +K PK+ + + +P R R P T Sbjct: 925 TPKPQKPTKAPKKPTSTKKPKTMP-RVRKPKT 955 Score = 75.5 bits (184), Expect = 2e-13 Identities = 112/489 (22%), Positives = 166/489 (33%), Gaps = 44/489 (8%) Query: 369 FSTGTPVAAATVAPILATNTIPSATTAGSVSHT-----QAPTSTIVTMTVPSHSSHATAV 423 F TP + T ++T+ P TTA ++ + TS ++TV ++ T Sbjct: 138 FKVTTPDTSTTQHNKVSTS--PKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKE 195 Query: 424 TTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPV 483 TT+ ++ T ++ Q L P S A P P A T + P Sbjct: 196 TTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK 255 Query: 484 QFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLN 543 + P P S TP + +TI+ P + + P A T A T Sbjct: 256 EPTPTTPKEPAST--------TPKEPTPTTIKSAPTTPKEP-----APTTTKSAPTTPKE 302 Query: 544 PMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGI-----QPAPLGTQGIHSATPIN 598 P T + + + PAP +T+ +PAP T +PAP + TP Sbjct: 303 PAPTTTKEPAPTTPKE---PAPTTTK--EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 357 Query: 599 ---TQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAA-PAATTVVQTHSQS 654 T +P P ++P P K A A P + PA TT + + Sbjct: 358 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 417 Query: 655 ASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVP 714 +P P P+ + P T + + TP S T P P Sbjct: 418 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 477 Query: 715 PTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITP----PITTIAAAPPPSVTVGGS 770 T ++P PT P A + P +PA + P P TP P T AP + + Sbjct: 478 TTPKKPAPTTPKE-PAPTTPKEPAPTTTKKP--APTTPKEPAPTTPKETAPTTPKKLTPT 534 Query: 771 LSSVLGPPVPE---IKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLP 827 L P PE EE+ P P P T + A PT+ Sbjct: 535 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 594 Query: 828 PGASPRKKP 836 P + K+P Sbjct: 595 PAPTTPKEP 603 Score = 48.1 bits (113), Expect = 4e-05 Identities = 128/598 (21%), Positives = 185/598 (30%), Gaps = 91/598 (15%) Query: 33 PRLGAPSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEK 92 P AP+T AP+ P T +E + +A + + + +E Sbjct: 536 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 595 Query: 93 QEPVVVRPYPQVQMLSTHHAVASATPVAVTAP-----PAHLTPA--VPLSFSEGLMKPP- 144 P P +T A TP TAP PA TP P + K P Sbjct: 596 APTTPKEPAP-----TTPKETAPTTPKG-TAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 649 Query: 145 -----------PKPTMPSRPIAPAPPSTLSLPPKVP-GQVTVTMESSIPQASAIPVATIS 192 PK T P+ P PAP + P P G T++ P P Sbjct: 650 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA---- 705 Query: 193 GQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRP- 251 P L T + AP P A P+ A + T P Sbjct: 706 -----PKELAPTTTKGPTSTTSDKPAPTTPKET-APTTPKEPAPTTPKKPAPTTPETPPP 759 Query: 252 -TSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAV--------VATVSATRAQSPV 302 TS++ T + IH+ P ++ P A+ V T A P Sbjct: 760 TTSEVSTPTTTKEPTT--IHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPE 817 Query: 303 ITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHT 362 +TTTA T R T P + + + TT T S T Q T Sbjct: 818 MTTTAKDKTTERDLRTT------PETTTAAPKMTKETATTTEKTTESK-ITATTTQVTST 870 Query: 363 MAQKTIFSTGTPVAAATVAPILATN--TIPSATTAGSVSHTQAP----TSTIVTMTVPSH 416 Q T T + T+AP + T TI + T P T++ T P Sbjct: 871 TTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK 930 Query: 417 SSHATAVTTSNI----------PVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASP 466 + A TS P P+++T T P + P + L + +P Sbjct: 931 PTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTP 990 Query: 467 NPVAMETRSDNR---------PSVPVQFQYFLPTYPPS-----AYPLAAHTYTPITSSVS 512 N +E + P + ++ F+P P P P+ S + Sbjct: 991 NSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDET 1050 Query: 513 TIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQ--PAPIST 568 I + + + T + G VA H M S AR I + P+PI T Sbjct: 1051 NI----CNGKPVDGLTTLRNGTLVAFRGHYFWMLSPFSPPSPARRITEVWGIPSPIDT 1104 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 116 bits (291), Expect = 1e-25 Identities = 182/872 (20%), Positives = 290/872 (33%), Gaps = 100/872 (11%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDES---GRDSEVSAREHMSSSSSLQSREEKQE 94 P++ S+ S N + T N ++ G++ SA+E S + Sbjct: 225 PNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTS 284 Query: 95 PVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPI 154 V+ +P P+ + +T A TP P TP P S + P + P+ P Sbjct: 285 KVLAKPTPKAE--TTTKGPALTTP----KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 338 Query: 155 APAPPSTLSLP--PKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMS 212 PAP +T S P PK P T + P T ++ P+ TT + + Sbjct: 339 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT---KEPAPTTTKSAPTTPKEPA 395 Query: 213 IIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQP 272 P P P+ A ++ K T P P P Sbjct: 396 PTTPKKPAPT-------TPKEPAP----TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 444 Query: 273 IQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISI 332 +P TT P + T + P TT A + S PT + + P+ S Sbjct: 445 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 504 Query: 333 QRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSA 392 + TT PA TPK+ T +K P AP P+ Sbjct: 505 PTTPKEPSPTT----TKEPAPTTPKEPAPTTPKKP-----APTTPKEPAPTTPKEPAPTT 555 Query: 393 TTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSP-RIQPDYPA 451 T + + + P T T P+ T T + A P++ T+P + P P Sbjct: 556 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL--APTTPEKPAPTTPEELAPTTPE 613 Query: 452 ERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSV 511 E + P +P A T + P+ P + P P P TP ++ Sbjct: 614 EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP 673 Query: 512 STIRQ-YPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQG 570 +T+++ P + + P P +L +PAP + +G Sbjct: 674 TTLKEPAPTTPKKP------------------APKELAPTTTKEPTSTTCDKPAPTTPKG 715 Query: 571 IQPA----PIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADG 626 P P T +PAP +G T +PAP ++P P K A G Sbjct: 716 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTL-----KEPAPTTPKKPAP--KELAPTTTKG 768 Query: 627 ATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEI 686 T + S PA TT +T + AP P P+ P T Sbjct: 769 PT-------STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS------- 814 Query: 687 HVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPG 746 ++TP T T +++ D+ T P + +P P A + P +P V + P Sbjct: 815 --EVSTPTTTKEPTTIHKSPDEST---PELSAEPTPK-----ALENSPKEPGVPTTKTPA 864 Query: 747 AVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATN 806 A P +TT A + + + P + E + + + + Sbjct: 865 AT--KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTST 922 Query: 807 TVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSL 866 T + L T+ L P + KK +++ E ET D + +K+ Sbjct: 923 TTQDTTPFKITTLK--TTTLAPKVTTTKKTITTTEIMNKPE----ETAKPKDRATNSKAT 976 Query: 867 LVKAEKRKSPPKEYIDEEGVRYVPVRPRPPIT 898 K +K PK+ + + +P R R P T Sbjct: 977 TPKPQKPTKAPKKPTSTKKPKTMP-RVRKPKT 1007 Score = 75.5 bits (184), Expect = 2e-13 Identities = 112/489 (22%), Positives = 166/489 (33%), Gaps = 44/489 (8%) Query: 369 FSTGTPVAAATVAPILATNTIPSATTAGSVSHT-----QAPTSTIVTMTVPSHSSHATAV 423 F TP + T ++T+ P TTA ++ + TS ++TV ++ T Sbjct: 190 FKVTTPDTSTTQHNKVSTS--PKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKE 247 Query: 424 TTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPV 483 TT+ ++ T ++ Q L P S A P P A T + P Sbjct: 248 TTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK 307 Query: 484 QFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLN 543 + P P S TP + +TI+ P + + P A T A T Sbjct: 308 EPTPTTPKEPAST--------TPKEPTPTTIKSAPTTPKEP-----APTTTKSAPTTPKE 354 Query: 544 PMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGI-----QPAPLGTQGIHSATPIN 598 P T + + + PAP +T+ +PAP T +PAP + TP Sbjct: 355 PAPTTTKEPAPTTPKE---PAPTTTK--EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 409 Query: 599 ---TQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAA-PAATTVVQTHSQS 654 T +P P ++P P K A A P + PA TT + + Sbjct: 410 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 469 Query: 655 ASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVP 714 +P P P+ + P T + + TP S T P P Sbjct: 470 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 529 Query: 715 PTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITP----PITTIAAAPPPSVTVGGS 770 T ++P PT P A + P +PA + P P TP P T AP + + Sbjct: 530 TTPKKPAPTTPKE-PAPTTPKEPAPTTTKKP--APTTPKEPAPTTPKETAPTTPKKLTPT 586 Query: 771 LSSVLGPPVPE---IKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLP 827 L P PE EE+ P P P T + A PT+ Sbjct: 587 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 646 Query: 828 PGASPRKKP 836 P + K+P Sbjct: 647 PAPTTPKEP 655 Score = 48.1 bits (113), Expect = 4e-05 Identities = 128/598 (21%), Positives = 185/598 (30%), Gaps = 91/598 (15%) Query: 33 PRLGAPSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEK 92 P AP+T AP+ P T +E + +A + + + +E Sbjct: 588 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 647 Query: 93 QEPVVVRPYPQVQMLSTHHAVASATPVAVTAP-----PAHLTPA--VPLSFSEGLMKPP- 144 P P +T A TP TAP PA TP P + K P Sbjct: 648 APTTPKEPAP-----TTPKETAPTTPKG-TAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 701 Query: 145 -----------PKPTMPSRPIAPAPPSTLSLPPKVP-GQVTVTMESSIPQASAIPVATIS 192 PK T P+ P PAP + P P G T++ P P Sbjct: 702 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA---- 757 Query: 193 GQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRP- 251 P L T + AP P A P+ A + T P Sbjct: 758 -----PKELAPTTTKGPTSTTSDKPAPTTPKET-APTTPKEPAPTTPKKPAPTTPETPPP 811 Query: 252 -TSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAV--------VATVSATRAQSPV 302 TS++ T + IH+ P ++ P A+ V T A P Sbjct: 812 TTSEVSTPTTTKEPTT--IHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPE 869 Query: 303 ITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHT 362 +TTTA T R T P + + + TT T S T Q T Sbjct: 870 MTTTAKDKTTERDLRTT------PETTTAAPKMTKETATTTEKTTESK-ITATTTQVTST 922 Query: 363 MAQKTIFSTGTPVAAATVAPILATN--TIPSATTAGSVSHTQAP----TSTIVTMTVPSH 416 Q T T + T+AP + T TI + T P T++ T P Sbjct: 923 TTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK 982 Query: 417 SSHATAVTTSNI----------PVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASP 466 + A TS P P+++T T P + P + L + +P Sbjct: 983 PTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTP 1042 Query: 467 NPVAMETRSDNR---------PSVPVQFQYFLPTYPPS-----AYPLAAHTYTPITSSVS 512 N +E + P + ++ F+P P P P+ S + Sbjct: 1043 NSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDET 1102 Query: 513 TIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQ--PAPIST 568 I + + + T + G VA H M S AR I + P+PI T Sbjct: 1103 NI----CNGKPVDGLTTLRNGTLVAFRGHYFWMLSPFSPPSPARRITEVWGIPSPIDT 1156 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 116 bits (291), Expect = 1e-25 Identities = 182/872 (20%), Positives = 290/872 (33%), Gaps = 100/872 (11%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDES---GRDSEVSAREHMSSSSSLQSREEKQE 94 P++ S+ S N + T N ++ G++ SA+E S + Sbjct: 266 PNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTS 325 Query: 95 PVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPI 154 V+ +P P+ + +T A TP P TP P S + P + P+ P Sbjct: 326 KVLAKPTPKAE--TTTKGPALTTP----KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 379 Query: 155 APAPPSTLSLP--PKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMS 212 PAP +T S P PK P T + P T ++ P+ TT + + Sbjct: 380 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT---KEPAPTTTKSAPTTPKEPA 436 Query: 213 IIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQP 272 P P P+ A ++ K T P P P Sbjct: 437 PTTPKKPAPT-------TPKEPAP----TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 485 Query: 273 IQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISI 332 +P TT P + T + P TT A + S PT + + P+ S Sbjct: 486 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 545 Query: 333 QRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSA 392 + TT PA TPK+ T +K P AP P+ Sbjct: 546 PTTPKEPSPTT----TKEPAPTTPKEPAPTTPKKP-----APTTPKEPAPTTPKEPAPTT 596 Query: 393 TTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSP-RIQPDYPA 451 T + + + P T T P+ T T + A P++ T+P + P P Sbjct: 597 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL--APTTPEKPAPTTPEELAPTTPE 654 Query: 452 ERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSV 511 E + P +P A T + P+ P + P P P TP ++ Sbjct: 655 EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAP 714 Query: 512 STIRQ-YPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQG 570 +T+++ P + + P P +L +PAP + +G Sbjct: 715 TTLKEPAPTTPKKP------------------APKELAPTTTKEPTSTTCDKPAPTTPKG 756 Query: 571 IQPA----PIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADG 626 P P T +PAP +G T +PAP ++P P K A G Sbjct: 757 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTL-----KEPAPTTPKKPAP--KELAPTTTKG 809 Query: 627 ATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEI 686 T + S PA TT +T + AP P P+ P T Sbjct: 810 PT-------STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS------- 855 Query: 687 HVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPG 746 ++TP T T +++ D+ T P + +P P A + P +P V + P Sbjct: 856 --EVSTPTTTKEPTTIHKSPDEST---PELSAEPTPK-----ALENSPKEPGVPTTKTPA 905 Query: 747 AVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATN 806 A P +TT A + + + P + E + + + + Sbjct: 906 AT--KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTST 963 Query: 807 TVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSL 866 T + L T+ L P + KK +++ E ET D + +K+ Sbjct: 964 TTQDTTPFKITTLK--TTTLAPKVTTTKKTITTTEIMNKPE----ETAKPKDRATNSKAT 1017 Query: 867 LVKAEKRKSPPKEYIDEEGVRYVPVRPRPPIT 898 K +K PK+ + + +P R R P T Sbjct: 1018 TPKPQKPTKAPKKPTSTKKPKTMP-RVRKPKT 1048 Score = 75.5 bits (184), Expect = 2e-13 Identities = 112/489 (22%), Positives = 166/489 (33%), Gaps = 44/489 (8%) Query: 369 FSTGTPVAAATVAPILATNTIPSATTAGSVSHT-----QAPTSTIVTMTVPSHSSHATAV 423 F TP + T ++T+ P TTA ++ + TS ++TV ++ T Sbjct: 231 FKVTTPDTSTTQHNKVSTS--PKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKE 288 Query: 424 TTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPV 483 TT+ ++ T ++ Q L P S A P P A T + P Sbjct: 289 TTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPK 348 Query: 484 QFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLN 543 + P P S TP + +TI+ P + + P A T A T Sbjct: 349 EPTPTTPKEPAST--------TPKEPTPTTIKSAPTTPKEP-----APTTTKSAPTTPKE 395 Query: 544 PMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGI-----QPAPLGTQGIHSATPIN 598 P T + + + PAP +T+ +PAP T +PAP + TP Sbjct: 396 PAPTTTKEPAPTTPKE---PAPTTTK--EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 450 Query: 599 ---TQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAA-PAATTVVQTHSQS 654 T +P P ++P P K A A P + PA TT + + Sbjct: 451 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 510 Query: 655 ASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVP 714 +P P P+ + P T + + TP S T P P Sbjct: 511 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 570 Query: 715 PTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITP----PITTIAAAPPPSVTVGGS 770 T ++P PT P A + P +PA + P P TP P T AP + + Sbjct: 571 TTPKKPAPTTPKE-PAPTTPKEPAPTTTKKP--APTTPKEPAPTTPKETAPTTPKKLTPT 627 Query: 771 LSSVLGPPVPE---IKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLP 827 L P PE EE+ P P P T + A PT+ Sbjct: 628 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKE 687 Query: 828 PGASPRKKP 836 P + K+P Sbjct: 688 PAPTTPKEP 696 Score = 48.1 bits (113), Expect = 4e-05 Identities = 128/598 (21%), Positives = 185/598 (30%), Gaps = 91/598 (15%) Query: 33 PRLGAPSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEK 92 P AP+T AP+ P T +E + +A + + + +E Sbjct: 629 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 688 Query: 93 QEPVVVRPYPQVQMLSTHHAVASATPVAVTAP-----PAHLTPA--VPLSFSEGLMKPP- 144 P P +T A TP TAP PA TP P + K P Sbjct: 689 APTTPKEPAP-----TTPKETAPTTPKG-TAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 742 Query: 145 -----------PKPTMPSRPIAPAPPSTLSLPPKVP-GQVTVTMESSIPQASAIPVATIS 192 PK T P+ P PAP + P P G T++ P P Sbjct: 743 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA---- 798 Query: 193 GQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRP- 251 P L T + AP P A P+ A + T P Sbjct: 799 -----PKELAPTTTKGPTSTTSDKPAPTTPKET-APTTPKEPAPTTPKKPAPTTPETPPP 852 Query: 252 -TSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAV--------VATVSATRAQSPV 302 TS++ T + IH+ P ++ P A+ V T A P Sbjct: 853 TTSEVSTPTTTKEPTT--IHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPE 910 Query: 303 ITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHT 362 +TTTA T R T P + + + TT T S T Q T Sbjct: 911 MTTTAKDKTTERDLRTT------PETTTAAPKMTKETATTTEKTTESK-ITATTTQVTST 963 Query: 363 MAQKTIFSTGTPVAAATVAPILATN--TIPSATTAGSVSHTQAP----TSTIVTMTVPSH 416 Q T T + T+AP + T TI + T P T++ T P Sbjct: 964 TTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK 1023 Query: 417 SSHATAVTTSNI----------PVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASP 466 + A TS P P+++T T P + P + L + +P Sbjct: 1024 PTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTP 1083 Query: 467 NPVAMETRSDNR---------PSVPVQFQYFLPTYPPS-----AYPLAAHTYTPITSSVS 512 N +E + P + ++ F+P P P P+ S + Sbjct: 1084 NSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINPMLSDET 1143 Query: 513 TIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQ--PAPIST 568 I + + + T + G VA H M S AR I + P+PI T Sbjct: 1144 NI----CNGKPVDGLTTLRNGTLVAFRGHYFWMLSPFSPPSPARRITEVWGIPSPIDT 1197 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 99.8 bits (247), Expect = 1e-20 Identities = 202/860 (23%), Positives = 313/860 (36%), Gaps = 127/860 (14%) Query: 3 PPRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINPAA 62 P P+AG + G +S + P P++G + N+ + +P Sbjct: 71 PESAPRAGPTRSAG-----------TSSRNPASRPPASGRGERAPPAKNTSPGPVSSP-- 117 Query: 63 TVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVT 122 GR S + + S EE P+ LS ++ P T Sbjct: 118 ------GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT 171 Query: 123 APPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQ 182 PA + GL P P P+ RP P ++S + T E S P Sbjct: 172 PSPAMARRSRAAGTEVGL--PRPAPSARPRPPTEGPRKSVSSASEHS-----TTEPS-PA 223 Query: 183 ASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSS 242 A P A G P++ + S RS GP A PR A A Sbjct: 224 ARRRPSA--GGGLQRPASRSLSSSATPLSSPARS---GP----SARGTPR-APAHPSQPK 273 Query: 243 SKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPV-TTSNAIPPA--VVATVSATRAQ 299 K LRP P A PA+ + P+ + P T + +PP + AT Sbjct: 274 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPP 333 Query: 300 SPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGT--PK 357 SP + T A S + P+L P A P+Q+ T + + P+L T P Sbjct: 334 SPPLATPLPLAPPSPSAPPSLQTLPSPPAT----PPSQAPPSMTTPPMQAPPSLQTIPPI 389 Query: 358 QQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSH-TQAPTSTIVTMTVPSH 416 Q H++ ++ + +P+A +++ AT ++ S T + S T +P T ++T PS Sbjct: 390 QVPHSLTSPSLQAPPSPLALSSLQ---ATTSLGSPTLQATHSFLTMSPRQTQASLTSPSR 446 Query: 417 SSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSD 476 A P +P P P ++SL P +SP + Sbjct: 447 P-------------ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIH------ 487 Query: 477 NRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGV 536 P+Q L ++ P A PL++ P+ + S P S Q P +++T + Sbjct: 488 -----PLQALSSLASHSPQA-PLSSLIMPPLETQSSLA---PPSLQTPPASLTTPPLENL 538 Query: 537 ASTVHLNPMQLMTVDASHAR-HIQGIQ-PAPISTQGIQPAPIGTPGIQ-PAPLGTQGIHS 593 S L P L T A H++ PAP Q P+P+ TP + P+ + T + Sbjct: 539 PS---LAPPPLQTASAPLTTPHLETPPCPAPCPLQA-PPSPLTTPPPETPSSIATPPPQA 594 Query: 594 ATPINTQGLQP------APMGTQQPQPEGKTSAVVLADGATIVANPISNPFSA-APAATT 646 + + LQ +P+ T PQ + L + A+P +P + +P A Sbjct: 595 PPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPN 654 Query: 647 VVQTHSQSASTNAPAQGSSPRP-SILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQN 705 + H A + P P S P + A P S+ S+A P Sbjct: 655 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP------------ 702 Query: 706 NDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALST----IPGAVPITPPITTIAAAP 761 + VPP+ PP P M +A+PP Q L+ +P + P +PP++ A P Sbjct: 703 ----PLQVPPS----PPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPP 754 Query: 762 P--PSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPL----ATNTVSPSLALL 815 P P + L PP + + +P P A PPL + P A Sbjct: 755 PRVPPLLAAPPLQVPPSPPA-SLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 813 Query: 816 ANNLSMPTSDL---PPGASP 832 + + S+P S L PP A P Sbjct: 814 SPSASLPMSPLATPPPQAPP 833 Score = 87.4 bits (215), Expect = 6e-17 Identities = 170/750 (22%), Positives = 266/750 (35%), Gaps = 106/750 (14%) Query: 52 SGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPV-----VVRPYPQVQM 106 S GL PA+ S AR S+ + ++ +P +RP PQV Sbjct: 229 SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP-PQVTP 287 Query: 107 LSTHHAVA----SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTL 162 A A S++P+A +P T A P+ + P P PS P+A P Sbjct: 288 PRKDAAPALGPLSSSPLATPSPSG--TKARPVPPPDNAATPLPATLPPSPPLATPLPLAP 345 Query: 163 SLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSN--APG 220 P P T+ + P + A P T Q PS L I V S+ + AP Sbjct: 346 PSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPS-LQTIPPIQVPHSLTSPSLQAPP 404 Query: 221 PPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVT 280 PL + + + + ++ T+ +Q + ++PA P S PP+ Sbjct: 405 SPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPA-----STPPDS-PPLQ 458 Query: 281 TSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRD 340 ++P + S + A SP+ + H + S + S Q P S+ I QS Sbjct: 459 APLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSL 518 Query: 341 VTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSH 400 + P P + L ++A + + P+ P L T P+ Sbjct: 519 APPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTT----PHLETPPCPAPCPL----- 569 Query: 401 TQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQP--DYPAERSSLIP 458 QAP S + T + SS AT + P A P SP + P P + + Sbjct: 570 -QAPPSPLTTPPPETPSSIATPPPQA--PPALASPPLQGLPSPPLSPLATPPPQAPPXLA 626 Query: 459 ISGHRASPNPVA------METRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVS 512 + +A P+P A + T S P+ P PP + P+ A P + VS Sbjct: 627 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 686 Query: 513 TIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQ 572 P A +A Q ++ ++P A P P++ +Q Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA----------PPPLAAPPLQ 736 Query: 573 --PAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIV 630 P+P +P + P+ + P L AP P P A++ Sbjct: 737 VPPSPPASPPMSPS--------ATPPPRVPPLLAAPPLQVPPSPP-----------ASLP 777 Query: 631 ANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVS- 689 +P++ P AP A + T A + PA P P + + +S Sbjct: 778 MSPLAKPPPQAPPA---LATPPLQALPSPPASFPGQAPF-----------SPSASLPMSP 823 Query: 690 MATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGA-V 748 +ATP + ++ P + VPP+ PP PT+ A PP+ PG Sbjct: 824 LATPPPQAPPVLA-----APLLQVPPS----PPASPTLQAPRRPPT---------PGPDT 865 Query: 749 PITPPITTIAAAPPPSVTVGGSLSSVLGPP 778 ++ P T+A AP P S SS L P Sbjct: 866 SVSGPRLTLALAPGPPPPPSRSPSSTLSGP 895 Score = 33.9 bits (76), Expect = 0.82 Identities = 42/158 (26%), Positives = 56/158 (35%), Gaps = 21/158 (13%) Query: 97 VVRPYPQVQ-MLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIA 155 + +P PQ L+T A +P A A +P+ L S PP P + + P+ Sbjct: 781 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 840 Query: 156 PAPPS-----TLSLP--PKVPGQVTVTMESSI---------PQASAIPVATISGQQGHPS 199 PPS TL P P PG T + P S P +T+SG P Sbjct: 841 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG----PD 896 Query: 200 NLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAA 237 H + +R GP AS P AA Sbjct: 897 LAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 934 >gi|167736355 mucin 4 isoform a [Homo sapiens] Length = 5284 Score = 96.7 bits (239), Expect = 1e-19 Identities = 179/793 (22%), Positives = 284/793 (35%), Gaps = 102/793 (12%) Query: 113 VASATPVAVT---------APPAHLTPAVPLSFSEGLMKPPPKPTMPSR----PIAPAPP 159 +++ATP+ VT P H+T A +S P P+ S P+ Sbjct: 971 ISNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDT 1030 Query: 160 STLSLPPKVPGQVTVTMESSIPQASAIPVA-TISGQQGHPSNLHHIMTTNVQMSIIRSNA 218 S+ S P VT +S ++ +PV T S GH + L T++ + Sbjct: 1031 SSESTGHVTPLPVTSFSSASTGDSTPLPVTDTSSASTGHVTPLP---VTSLSSASTGDTT 1087 Query: 219 PGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPP 278 P P ++ A + V +S V+T T+ LP T+ + H P+ Sbjct: 1088 PLPVTDTSSASTGH-ATSLPVTDTSSVST--GHTTPLPVTDTSSASTGHATSLPVTDTSS 1144 Query: 279 VTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQS 338 V+T + P V SA+ Q+ + T+ + + + P L + P SA+ P Sbjct: 1145 VSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTP-LPVTSPSSASTGHATPLLV 1203 Query: 339 RDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSV 398 D ++ T TP + T +T PV + A T +P T S Sbjct: 1204 TDTSSAST-----GHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLP-VTDTSSA 1257 Query: 399 SHTQAPTSTIVTMTVPSHSSHATAV---TTSNIPVAKVVPQQITH-TSPRIQPDYPAERS 454 S QA TS +VT T + T + +TS+ V P +T +S P + Sbjct: 1258 STGQA-TSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVT 1316 Query: 455 SLIPISGHRASPNPVAMETRSDNRPSVP--------VQFQYFLPTYPPSAYPLAAHTYTP 506 SL S P PV + + + P V + P + A + TP Sbjct: 1317 SLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLHVTDASSASTGQATP 1376 Query: 507 IT----SSVSTIRQYPVSAQAPNSAITAQ------TGVGVASTVHLNPMQLM---TVDAS 553 + SSVST P+ +P+SA T T AST H P+ + +V Sbjct: 1377 LPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTD 1436 Query: 554 HARHIQGIQPAPISTQGIQPAPI----------------------GTPGIQPAPLGTQGI 591 HA + P+ ST P P+ T P P+ + Sbjct: 1437 HATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSS 1496 Query: 592 HSA---TPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVV 648 S TP++ A G P P S+ D + P+++P SA+ TT + Sbjct: 1497 ASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPL---PVTSPSSASTGDTTPL 1553 Query: 649 Q-THSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMA-----TPVTVSMETVS 702 T + S ST ++P P +T P S A TP+ V+ + + Sbjct: 1554 PVTDASSVSTGH----TTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSA 1609 Query: 703 NQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPI---TPPITTIAA 759 + + P ++ T P + AS +LST A P+ +P + Sbjct: 1610 STGHTTPLPVTDTSSASTGDTTPLPVTNAS-------SLST-GHATPLHVTSPSSASTGH 1661 Query: 760 APPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNL 819 A P VT S S+ P+P + PV+ V +T +P +++ Sbjct: 1662 ATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSASTGQATPLPVTSLSSV 1721 Query: 820 SMPTSDLPPGASP 832 S + P SP Sbjct: 1722 STGDTTPLPVTSP 1734 Score = 96.7 bits (239), Expect = 1e-19 Identities = 190/878 (21%), Positives = 307/878 (34%), Gaps = 124/878 (14%) Query: 51 NSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTH 110 +S S G P V D S + + H++S SS + + PV +ST Sbjct: 3175 SSVSTGHATPLL-VTDASSASTGHATPLHVTSPSSASTGDTTPVPVT-----DTSSVSTG 3228 Query: 111 HAVASATPVAVTAPPAHLT------PAVPLSF-SEGLMKPPPKPTMPS------RPIAPA 157 HA TP+ VT + T P +S S G P P S P+ Sbjct: 3229 HA----TPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDTMPLPVT 3284 Query: 158 PPSTLSLPPKVPGQVTVTMESSIPQASAIPV-ATISGQQGHPSNLHHIMTTN-------- 208 PS+ S P VT T +S A+ +PV +T S GH + L T++ Sbjct: 3285 SPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTPLPVTDTSSASTGDTTP 3344 Query: 209 --VQMSIIRSNAPGPPLH--IGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPA 264 V S PLH I +S + V +S +T + LP T+ + Sbjct: 3345 LPVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGASSAST--GHATPLPVTDTSSVS 3402 Query: 265 VQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTL---- 320 H P+ S V+T + P V SA+ Q+ + T+ + + + P L Sbjct: 3403 TGHATPLPVTSLSSVSTGDTTPLPVTDASSASTGQATPLPVTSLSSVSTGDTTPLLVTDA 3462 Query: 321 ---SIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTG--TPV 375 S H ++ A + D TTR+ + + T + + + STG TP+ Sbjct: 3463 SSVSTGHATPLPVTDTSSASTGD-TTRLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPL 3521 Query: 376 AAATVAPILATNTIPSATTAGSVSHTQAPTSTIVT--------------MTVPSHSS--H 419 + + + P T S + T T VT +T+PS SS H Sbjct: 3522 LVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPLPVTIPSSSSSGH 3581 Query: 420 ATAV---TTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSD 476 T + +TS++ V P +T S + +P++ ++ A Sbjct: 3582 TTPLPVTSTSSVSTGHVTPLHVTSPSSA-----STGHVTPLPVTSTSSASTGHATPLLVT 3636 Query: 477 NRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGV 536 + SV LP S+ T P+T + S + QA +T+ + V Sbjct: 3637 DASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSAS-----TGQATPLPVTSLSSVST 3691 Query: 537 ASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATP 596 T L + HA + P+ +ST P P+ +P + ATP Sbjct: 3692 GDTTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSP-------SSASTGHATP 3744 Query: 597 INTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATT-VVQTHSQSA 655 + GL A G P P TS+ + P+++ SA+ TT + T SA Sbjct: 3745 LPVTGLSSASTGDTTPLPVTDTSSASTRHATPL---PVTDTSSASTDDTTRLPVTDVSSA 3801 Query: 656 STNAPAQGSSPRPSILRKKPATDGAKP-----KSEIHVSMATPVTVSMETVSNQNNDQPT 710 ST ++P P +T P S + AT + V+ + ++ + P Sbjct: 3802 STG----HATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHATPL 3857 Query: 711 IAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGS 770 P T + ++ P + S++ + A P VT S Sbjct: 3858 ----------PVTDTSSVSTGHATPLPVTSTSSV-----------STGHATPLPVTSPSS 3896 Query: 771 LSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT------NTVSPSLALLANNLSMPTS 824 S+ PVP PV+ L+T + SPS A + ++P + Sbjct: 3897 ASTGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASRGDTSTLPVT 3956 Query: 825 DLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKST 862 D ++ P + S GD TD ++ Sbjct: 3957 DASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSAS 3994 Score = 92.8 bits (229), Expect = 1e-18 Identities = 189/817 (23%), Positives = 291/817 (35%), Gaps = 83/817 (10%) Query: 39 STG-LSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVV 97 STG + P +S S G P V D S + + ++S SS+ + + PV Sbjct: 2762 STGHATPLPLTSLSSVSTGDTTPLP-VTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVT 2820 Query: 98 VRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPL---SFSEGLMKPPPKPTMPSRPI 154 ST HA + +A H TP S S G P S I Sbjct: 2821 -----DTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDTSSASI 2875 Query: 155 APAPP------STLSLPPKVPGQVTVTMESSIPQASAIPVA-TISGQQGHPSNLHHIMTT 207 A S++S P VT +S A+ +PV T S GH + LH Sbjct: 2876 GHATSLPVTDTSSISTGHATPLHVTSPSSASTGHATPLPVTDTSSASTGHANPLH----V 2931 Query: 208 NVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQH 267 S +A P+ +S A V S S V+T T+ LP + + + H Sbjct: 2932 TSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVST--GDTTPLPVTSPSSASTGH 2989 Query: 268 IIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPV--ITTTAAHATDSALSRPTLSIQHP 325 P+ +T A V +T SA+ + +T T++ +T A P S+ Sbjct: 2990 TTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPVTSLSS- 3048 Query: 326 PSAAISIQRPAQSRDVTTR-ITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPIL 384 + D T +T PS + G L T A TP+ +++ + Sbjct: 3049 ----------VSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVS 3098 Query: 385 ATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAV---TTSNIPVAKVVPQQITHT 441 +T P T+ S + T TS VT T + + T++ TS+ +T T Sbjct: 3099 TGDTTPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDT 3158 Query: 442 SPRIQPD-YPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLA 500 S D P + +S A+P V + + + P L PS+ Sbjct: 3159 SSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTGHATP------LHVTSPSSASTG 3212 Query: 501 AHTYTPI--TSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHI 558 T P+ TSSVST P+ +SA T T L + + A + Sbjct: 3213 DTTPVPVTDTSSVSTGHATPLPVTGLSSAST-------GDTTRLPVTDISSASTGQATPL 3265 Query: 559 QGIQPAPISTQGIQPAPIGTPG------IQPAPLGTQGIHS---ATPINTQGLQPAPMGT 609 + +ST P P+ +P P P+ + S ATP+ A G Sbjct: 3266 PVTNTSSVSTGDTMPLPVTSPSSASTGHATPLPVTSTSSASTGHATPVPVTSTSSASTGH 3325 Query: 610 QQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQ-THSQSAST----NAPAQG- 663 P P TS+ D + P+++P SA+ TT + T SAST P G Sbjct: 3326 TTPLPVTDTSSASTGDTTPL---PVTSPSSASTGHTTPLHVTIPSSASTGDTSTLPVTGA 3382 Query: 664 SSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPT 723 SS P TD S + ATP+ V+ + + + P ++ Sbjct: 3383 SSASTGHATPLPVTD----TSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDASSASTGQA 3438 Query: 724 IPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIK 783 P + + S S T P V ++T A P P VT S S+ +P Sbjct: 3439 TPLPVTSLSSVSTG----DTTPLLVTDASSVSTGHATPLP-VTDTSSASTGDTTRLPVTD 3493 Query: 784 VKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLS 820 PV+++ ++T +P L A+++S Sbjct: 3494 TSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVS 3530 Score = 91.3 bits (225), Expect = 4e-18 Identities = 175/797 (21%), Positives = 278/797 (34%), Gaps = 113/797 (14%) Query: 143 PPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVA-TISGQQGHPSNL 201 PP P++ S + T +L P G+ T + I A+ +PV S GH + L Sbjct: 936 PPTPPSITSTGLTSPQTETHTLSPSGSGKTFTT--ALISNATPLPVTYASSASTGHTTPL 993 Query: 202 HHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTS-------- 253 H ++V P + H S+ T L TS Sbjct: 994 HVTDASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGD 1053 Query: 254 --QLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSAT--RAQSPVITTTAAH 309 LP T+ + H+ P+ S +T + P V T SA+ A S +T T++ Sbjct: 1054 STPLPVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHATSLPVTDTSSV 1113 Query: 310 ATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIF 369 +T P + + + V+T T P H T A Sbjct: 1114 STGHTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLHV----------TDASSAST 1163 Query: 370 STGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHAT-------- 421 TP+ +++ + +T P T+ S + T T +VT T + + HAT Sbjct: 1164 GQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDAS 1223 Query: 422 AVTT---SNIPVAKVVPQQITHTSPRIQPDYPA----ERSSLI-----PISGHRASPNPV 469 +V+T +++PV HT+P D + + +SL+ +S +P PV Sbjct: 1224 SVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPV 1283 Query: 470 AMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPIT--SSVSTIRQYPVSAQAPNSA 527 + + P L PS+ T P+T SS ST P+ +P+SA Sbjct: 1284 TSTSSASTGHVTP------LHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSA 1337 Query: 528 ITAQ------TGVGVASTVHLNPMQLMTVDASHARHIQGIQPAP------ISTQGIQPAP 575 T T ST H P+ + DAS A Q P P +ST P P Sbjct: 1338 STGDTTPLPVTDASSVSTGHTTPLHV--TDASSASTGQA-TPLPVTSLSSVSTGDTTPLP 1394 Query: 576 IGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPIS 635 + +P + ATP+ A G P P S+ V D AT + P++ Sbjct: 1395 VTSP-------SSASTGHATPLLVTDTSSASTGHATPLPVTDASS-VSTDHATSL--PVT 1444 Query: 636 NPFSAAPAATTVVQ-THSQSAST------------NAPAQGSSPRPSILRKKPATDGAKP 682 P +A+ TT + T + SAST + ++P P +T P Sbjct: 1445 IPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTP 1504 Query: 683 -----KSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAAS----- 732 S ATP+ V+ + ++ + P P++ T P + AS Sbjct: 1505 LHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTG 1564 Query: 733 -----PPSQPAVALSTIPGAVPITPPITTIAA-APPPSVTVGGSLSSVLGPPVPEIKVKE 786 P + P+ A + +P+T + P VT S S+ P+P Sbjct: 1565 HTTPLPVTSPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTTPLPVTDTSS 1624 Query: 787 EVEPMDIMRPVSAVPPLAT------NTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQ 840 PV+ L+T + SPS A + +P + ++ P Sbjct: 1625 ASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVT 1684 Query: 841 HVISTEEGDMMETNSTD 857 + S D TD Sbjct: 1685 GLSSATTDDTTRLPVTD 1701 Score = 88.2 bits (217), Expect = 4e-17 Identities = 195/870 (22%), Positives = 307/870 (35%), Gaps = 157/870 (18%) Query: 39 STG-LSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVV 97 STG ++ P +S S G P V D S + + ++ +SS+ + PV Sbjct: 1066 STGHVTPLPVTSLSSASTGDTTPLP-VTDTSSASTGHATSLPVTDTSSVSTGHTTPLPVT 1124 Query: 98 VRPYPQVQMLSTHHAVASATPVAVTAP-------PAHLTPAVPLSFSEGLMKPPPKPTMP 150 ST HA ++ PV T+ P H+T A S S G P P ++ Sbjct: 1125 -----DTSSASTGHA--TSLPVTDTSSVSTGHTTPLHVTDAS--SASTGQATPLPVTSLS 1175 Query: 151 S------RPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHI 204 S P+ PS+ S P VT T +S A+ +PV S + H Sbjct: 1176 SVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSV-----STDHA 1230 Query: 205 MTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPA 264 + V + S PL + + A +++ + + T+ LP +T+ + Sbjct: 1231 TSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSAS 1290 Query: 265 VQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS---PVIT----------------- 304 H+ + S +T +A P V + SA+ + PV + Sbjct: 1291 TGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDA 1350 Query: 305 -------TTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALG--T 355 TT H TD++ + Q P S+ + +T PS + G T Sbjct: 1351 SSVSTGHTTPLHVTDASSASTG---QATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHAT 1407 Query: 356 PKQQLHTMAQKTIFSTGTPVA-AATVAPILATN---TIPSATTAGSVSHTQAPTSTIVTM 411 P T + T +T PV A++V+ AT+ TIPSA + G HT T VT Sbjct: 1408 PLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTG---HT---TPLPVTD 1461 Query: 412 TVPSHSSHATAVT---TSNIPVAKVVPQQITHTSP----RIQPDYPAERSSLIPISGHRA 464 T + + AT++ TS++ P +T TS + P + SS +GH A Sbjct: 1462 TSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSAS--TGH-A 1518 Query: 465 SPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPIT--SSVSTIRQYPVSAQ 522 +P PV + + ++P LP PS+ T P+T SSVST P+ Sbjct: 1519 TPLPVTSLSSASTGDTMP------LPVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVT 1572 Query: 523 APNSAITAQT------GVGVASTVHLNPMQLMTVDASHARHIQGIQPAPI------STQG 570 +P+SA T T AS P+ + + ++ H P P+ ST Sbjct: 1573 SPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGHTT---PLPVTDTSSASTGD 1629 Query: 571 IQPAPI----------GTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSA 620 P P+ TP +P H ATP+ A G P P S+ Sbjct: 1630 TTPLPVTNASSLSTGHATPLHVTSPSSASTGH-ATPLPVTSTSSASTGHATPLPVTGLSS 1688 Query: 621 VVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGA 680 D + +S+ + V S S P +SP Sbjct: 1689 ATTDDTTRLPVTDVSSASTGQATPLPVTSLSSVSTGDTTPLPVTSP-------------- 1734 Query: 681 KPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVA 740 S A+P+ V+ + ++ P P T + ++ A P Sbjct: 1735 ---SSASTGHASPLLVTDASSASTGQATPL----------PVTDTSSVSTAHATPLPVTG 1781 Query: 741 LSTIPGAVPITPPITTIAAAP-----PPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMR 795 LS+ P+T +++A P VT S S+ P+P Sbjct: 1782 LSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSASTGDTTSL 1841 Query: 796 PVSAVPPLATNTVSPSLALLANNLSMPTSD 825 PV+ PS A + S+P +D Sbjct: 1842 PVTI----------PSSASSGHTTSLPVTD 1861 Score = 86.7 bits (213), Expect = 1e-16 Identities = 186/830 (22%), Positives = 296/830 (35%), Gaps = 120/830 (14%) Query: 100 PYPQVQMLSTHHAVASATPVAVTAPPAHLT-PAVPL------SFSEGLMKPPPKPTMPS- 151 P +ST HA TP+ VT+ + T PL S S G P P ++ S Sbjct: 3394 PVTDTSSVSTGHA----TPLPVTSLSSVSTGDTTPLPVTDASSASTGQATPLPVTSLSSV 3449 Query: 152 -----RPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVA-TISGQQGHPSNLHHIM 205 P+ S++S P VT T +S + +PV T S G + L Sbjct: 3450 STGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQATPL---- 3505 Query: 206 TTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVM----SSSKVTTVLRPTSQLPNAATA 261 +S + + P L AS + G A + S+S T P + +A+T Sbjct: 3506 -PVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTG 3564 Query: 262 QP-----------AVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHA 310 Q + H P+ S V+T + P V + SA+ + T+ + Sbjct: 3565 QATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSS 3624 Query: 311 TDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFS 370 + + P L + S + P D ++ T + P T T Sbjct: 3625 ASTGHATPLL-VTDASSVSTGHATPLPVTDASSASTGDTTPLPVTDTSSAST-------G 3676 Query: 371 TGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTM--TVPSHSSHATAVTT-SN 427 TP+ +++ + +T P T S + T T VT+ +V + + VT+ S+ Sbjct: 3677 QATPLPVTSLSSVSTGDTTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSS 3736 Query: 428 IPVAKVVPQQITHTSPRIQPDY-PAERSSLIPISGHRASPNPVA--METRSDNRPSVPVQ 484 P +T S D P + S A+P PV +D+ +PV Sbjct: 3737 ASTGHATPLPVTGLSSASTGDTTPLPVTDTSSASTRHATPLPVTDTSSASTDDTTRLPVT 3796 Query: 485 FQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQ------TGVGVAS 538 T + P+ + TSS ST P+ +S T T AS Sbjct: 3797 DVSSASTGHATPLPVTS------TSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSAS 3850 Query: 539 TVHLNPMQLM---TVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSAT 595 T H P+ + +V HA + + +ST P P+ +P + AT Sbjct: 3851 TGHATPLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTSPS-------SASTGHAT 3903 Query: 596 PINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAAT-TVVQTHSQS 654 P+ A G P P T+A L+ G + +++P SA+ T T+ T + S Sbjct: 3904 PVPVTSTSSASTGDTTPLPV--TNASSLSTGHATPLH-VTSPSSASRGDTSTLPVTDASS 3960 Query: 655 ASTNAPAQGSSPRPSILRKKPATDGAKP-----KSEIHVSMATPVTVSMETVSNQNNDQP 709 AST ++P P +T P S ATP+ V+ + + + P Sbjct: 3961 ASTGH----ATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTP 4016 Query: 710 TIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAA-----PPPS 764 P TIP+ ++ S P S++ P+T+ ++A P Sbjct: 4017 L----------PVTIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSASTGDTTPLP 4066 Query: 765 VTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTS 824 VT S S+ P+P PV+++ ++T +P A + S +S Sbjct: 4067 VTDTSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGHATPLAVSSATSASTVSS 4126 Query: 825 DLP-----PG-ASPRKK------------PRKQQHVISTEEGDMMETNST 856 D P PG +P K P Q +IST M T ST Sbjct: 4127 DSPLKMETPGMTTPSLKTDGGRRTATSPPPTTSQTIISTIPSTAMHTRST 4176 Score = 79.3 bits (194), Expect = 2e-14 Identities = 172/843 (20%), Positives = 293/843 (34%), Gaps = 111/843 (13%) Query: 64 VNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVR-----------PYPQVQMLSTHHA 112 V D S + + H++ +SSL + + PV P +ST HA Sbjct: 2099 VTDASSVSTGHATALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTGHA 2158 Query: 113 VASATPVAVTAPPAHLTPAVPL----SFSEGLMKPPP------KPTMPSRPIAPAPPSTL 162 + +A H T ++P+ S S G P P T + P+ PS+ Sbjct: 2159 TSLPVTDTSSASTGHAT-SLPVTDTSSASTGHATPLPVTDTSSASTGQATPLPVTSPSSA 2217 Query: 163 SLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPP 222 S +P VT T +S QA+ +PV ++S + + + S+ +A P Sbjct: 2218 STGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDAS---SVSTGHATSLP 2274 Query: 223 LHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTS 282 + +S V S S +T + +A++A + H P+ S +T Sbjct: 2275 VTSLSSVSTGDTTPLPVTSPSSASTGHATPLHVTDASSA--STGHATPLPVTSLSSASTG 2332 Query: 283 NAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVT 342 + P V + SA+ + + T A + + + P L + SA+ P D + Sbjct: 2333 DTTPLPVTSPSSASTGHATPLHVTDASSVSTGDTTP-LPVTSSSSASSGHTTPLPVTDAS 2391 Query: 343 TRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQ 402 + T + TP T + T +T PV + A T +P + Sbjct: 2392 SASTGDT-----TPLPVTDTSSASTGHATHLPVTGLSSASTGDTTRLPVTNV------SS 2440 Query: 403 APTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGH 462 A T + V S SS +T TT +P HT+P + D + +S Sbjct: 2441 ASTGHATPLPVTSTSSASTGDTTP-LPGTDTSSVSTGHTTPLLVTDASS-------VSTG 2492 Query: 463 RASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPIT--SSVSTIRQYPVS 520 + PV + + + P LP + T P+T SS+ST + Sbjct: 2493 DTTRLPVTSPSSASTGHTTP------LPVTDTPSASTGDTTPLPVTNASSLSTRHATSLH 2546 Query: 521 AQAPNSAITAQ------TGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPI----STQG 570 +P+SA T T AST H P + V ++ + P P+ S Sbjct: 2547 VTSPSSASTGHATSLPVTDTSAASTGHATP---LPVTSTSSASTGDTTPLPVTDTYSAST 2603 Query: 571 IQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIV 630 Q P+ A G TP+ A G P P TS+V + Sbjct: 2604 GQATPLPVTDTSSASTG-----DTTPLPVTDTSSASTGHATPLPVTNTSSVSTGHATPL- 2657 Query: 631 ANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSM 690 +++P SA+ TT + S+ + A P TD S + Sbjct: 2658 --HVTSPSSASTGHTTPLPVTDASSVSTGHA----------TSLPVTDA----SSVFTGH 2701 Query: 691 ATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPI 750 AT + V++ + ++ + P P T + ++ S P S++ Sbjct: 2702 ATSLPVTIPSSASSGHTTPL----------PVTDASSVSTGHATSLPVTDASSVSTGHAT 2751 Query: 751 TPPITTIAA-----APPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT 805 P+T ++ A P +T S+S+ P+P PV+++ ++T Sbjct: 2752 PLPVTDASSVSTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVST 2811 Query: 806 NTVSP------SLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDE 859 +P S A + S+P +D ++ P S G TD Sbjct: 2812 GDTTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDTS 2871 Query: 860 KST 862 ++ Sbjct: 2872 SAS 2874 Score = 77.0 bits (188), Expect = 8e-14 Identities = 185/849 (21%), Positives = 289/849 (34%), Gaps = 132/849 (15%) Query: 50 ANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLST 109 A+S S G P V D S + + ++ SS + + + PV V ST Sbjct: 1750 ASSASTGQATPLP-VTDTSSVSTAHATPLPVTGLSSASTDDTTRLPVT-----DVSSAST 1803 Query: 110 HHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVP 169 A+ P+ VT+P S S G P P S T SLP +P Sbjct: 1804 GQAI----PLPVTSPS---------SASTGDTTPLPVTDASSASTG----DTTSLPVTIP 1846 Query: 170 GQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGP-------- 221 + +S+P A V+T GH ++L + T+ P P Sbjct: 1847 SSASSGHTTSLPVTDASSVST-----GHATSL---LVTDASSVSTGDTTPLPVTDTNSAS 1898 Query: 222 -----PLHI-GASHLPRG-AAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQ 274 PLH+ AS + G A + V S S +T T+ LP + + + H P+ Sbjct: 1899 TGDTTPLHVTDASSVSTGHATSLPVTSLSSAST--GDTTPLPVTSPSSASSGHTTPLPVT 1956 Query: 275 SRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQR 334 V T +A V S + + + T A + + + P L + S + Sbjct: 1957 DASSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATP-LPVTDTSSVSTGQAT 2015 Query: 335 PAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATT 394 P +++ T + P T T TP+ +++ + +T P T Sbjct: 2016 PLPVTSLSSASTGDTTPLPVTDTSSAST-------GQDTPLPVTSLSSVSTGDTTPLPVT 2068 Query: 395 AGSVSHTQAPTSTIVTMTVPSHSSHATAV---TTSNIPVAKVVPQQITHTSPRIQPD-YP 450 + S + T T +VT + HAT++ S++ +T S D P Sbjct: 2069 SPSSASTGHATPLLVTDASSVSTGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTP 2128 Query: 451 AERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPI--T 508 +S S +P PV + SV LP S+ T P+ T Sbjct: 2129 LPVTSPSSASTGDTTPLPVT------DTSSVSTGHATSLPVTDTSSASTGHATSLPVTDT 2182 Query: 509 SSVSTIRQYPVSAQAPNSAITAQ------TGVGVASTVHLNPMQLMTVDASHARHIQGIQ 562 SS ST P+ +SA T Q T AST H P L+ D S A Sbjct: 2183 SSASTGHATPLPVTDTSSASTGQATPLPVTSPSSASTGHAIP--LLVTDTSSA------- 2233 Query: 563 PAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVV 622 ST P P+ L + TP+ G P S+V Sbjct: 2234 ----STGQATPLPV-------TSLSSASTGDTTPLPVTDASSVSTGHATSLPVTSLSSVS 2282 Query: 623 LADGATIVANPISNPFSAAPA-ATTVVQTHSQSAST------------NAPAQGSSPRPS 669 D + P+++P SA+ AT + T + SAST +A ++P P Sbjct: 2283 TGDTTPL---PVTSPSSASTGHATPLHVTDASSASTGHATPLPVTSLSSASTGDTTPLPV 2339 Query: 670 ILRKKPATDGAKP-----KSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTI 724 +T A P S + TP+ V+ + ++ + P ++ T Sbjct: 2340 TSPSSASTGHATPLHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTT 2399 Query: 725 PTMIAAASPPSQ------PAVALSTIPGAVPITPPITTIAA-----APPPSVTVGGSLSS 773 P + S S P LS+ P+T +++ A P VT S S+ Sbjct: 2400 PLPVTDTSSASTGHATHLPVTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSAST 2459 Query: 774 VLGPPVPEIKVKE----EVEPMDI--MRPVSAVPPLATNTVSPSLALLANNLSMPTSDLP 827 P+P P+ + VS SPS A + +P +D P Sbjct: 2460 GDTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRLPVTSPSSASTGHTTPLPVTDTP 2519 Query: 828 PGASPRKKP 836 ++ P Sbjct: 2520 SASTGDTTP 2528 Score = 62.0 bits (149), Expect = 3e-09 Identities = 194/881 (22%), Positives = 317/881 (35%), Gaps = 128/881 (14%) Query: 47 SQIANSGSAGLINPAATVN-DESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQ 105 S + +GS + AA V D G+ +R +++ + Q R V Sbjct: 281 SSVPVTGSLMPVTSAALVTFDPEGQSPATFSRTSTQDTTAFSKNHQTQSVETTR----VS 336 Query: 106 MLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLP 165 ++T + + T V + P+ P+ +S + T PS + PS++S Sbjct: 337 QINTLNTLTPVTTSTVLSSPSGFNPSGTVS----------QETFPSGETTTSSPSSVSNT 386 Query: 166 PKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHI 225 V +V M +S T G S + ++T + S S A P Sbjct: 387 FLVTSKV-FRMPTSRDSTLGNTEETSLSVSGTISAITSKVST-IWWSDTLSTALSP---- 440 Query: 226 GASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAI 285 +S P+ + A S T RP + ++ P V Q I + TT Sbjct: 441 -SSLPPKISTAFHTQQSEGAETTGRPHER----SSFSPGVS----QEIFTLHETTTW--- 488 Query: 286 PPAVVATVSATRAQSPVITTTAAHATDSALSRPTL----SIQHPPSAAISIQRPAQSRDV 341 P + + T +Q+ + +T+ AT P+ +I PS +I P + Sbjct: 489 PSSFSSKGHTTWSQTELPSTSTGAATRLVTGNPSTGTAGTIPRVPSKVSAIGEPGEPTTY 548 Query: 342 TTR-ITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILA-TNTIPSATTAGSVS 399 ++ TLP G Q TGT A +P + T I +AT+ S Sbjct: 549 SSHSTTLPKTTGAGAQTQWTQ--------ETGTTGEALLSSPSYSVTQMIKTATSPSSSP 600 Query: 400 HTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPI 459 TS +T T PS ++H+T +TS P Q HT S+ P+ Sbjct: 601 MLDRHTSQQIT-TAPS-TNHSTIHSTSTSPQESPAVSQRGHTQAPQTTQESQTTRSVSPM 658 Query: 460 SGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPV 519 + + P + T S + PS +P P+ AA T+ P + Q P Sbjct: 659 TDTKTVTTPGSSFTASGHSPS------EIVPQDAPTI--SAATTFAPAPTGDGHTTQAPT 710 Query: 520 SA--QAPNS----------AITAQTGV-----GVASTVHLNPMQLMTVDAS--------- 553 +A AP+S ++TG V ST Q + AS Sbjct: 711 TALQAAPSSHDATLGPSGGTSLSKTGALTLANSVVSTPGGPEGQWTSASASTSPDTAAAM 770 Query: 554 -HARHIQGIQPAPISTQGIQPAPIG--TPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQ 610 H + + A TQ +PA G T A + G TP ++G+ + T+ Sbjct: 771 THTHQAESTE-ASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTR 829 Query: 611 ---QPQPEGKT---SAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGS 664 P + T + +L+ A+ A P+S +++ T T S++++ P S Sbjct: 830 FSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQS 889 Query: 665 SP-RPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIA-VPPTAQQPPP 722 SP PS ++ A S + + T + +T+S + T + VPPT PP Sbjct: 890 SPTSPSASPQETAA-----ISRMAQTQRTRTSRGSDTISLASQATDTFSTVPPT----PP 940 Query: 723 TIPTMIAAASP--------PSQPAVALST--IPGAVPITPPITTIAAA-----PPPSVTV 767 +I T SP PS +T I A P+ P+T ++A P VT Sbjct: 941 SI-TSTGLTSPQTETHTLSPSGSGKTFTTALISNATPL--PVTYASSASTGHTTPLHVTD 997 Query: 768 GGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSP------SLALLANNLSM 821 S+S+ P+P PV+ +T V+P S A ++ + Sbjct: 998 ASSVSTGHATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPL 1057 Query: 822 PTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKST 862 P +D ++ P + S GD TD ++ Sbjct: 1058 PVTDTSSASTGHVTPLPVTSLSSASTGDTTPLPVTDTSSAS 1098 Score = 60.8 bits (146), Expect = 6e-09 Identities = 115/497 (23%), Positives = 174/497 (35%), Gaps = 73/497 (14%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVV 97 P TGLS A S G P V D S + + ++ +SS + + + PV Sbjct: 3746 PVTGLSSA--------STGDTTPLP-VTDTSSASTRHATPLPVTDTSSASTDDTTRLPVT 3796 Query: 98 VRPYPQVQMLSTHHAV---ASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPI 154 V ST HA ++T A T L S S G P + S Sbjct: 3797 -----DVSSASTGHATPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSAST 3851 Query: 155 APAPP------STLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTN 208 A P S++S P VT T S A+ +PV + S ++ H Sbjct: 3852 GHATPLPVTDTSSVSTGHATPLPVTSTSSVSTGHATPLPVTSPSS-----ASTGHATPVP 3906 Query: 209 VQMSIIRSNAPGPPLHI-GASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQH 267 V + S PL + AS L G A ++S + TS LP + + H Sbjct: 3907 VTSTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSAS-RGDTSTLPVTDASSASTGH 3965 Query: 268 IIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPS 327 P+ S V+T + P V T SA+ Q+ + T+ + + + P Sbjct: 3966 ATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPL-------- 4017 Query: 328 AAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATN 387 +T+PS + G T A GTP+ + + + Sbjct: 4018 ----------------PVTIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSASTGD 4061 Query: 388 TIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQP 447 T P T S + T T VT T + + HAT +PV + H +P Sbjct: 4062 TTPLPVTDTSSASTGHATPLPVTDTSSASTGHATP-----LPVTSLSSVSTGHATPLAVS 4116 Query: 448 DYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPI 507 A +S + +S +P+ MET PS+ T PP P + T I Sbjct: 4117 S--ATSASTV------SSDSPLKMETPGMTTPSLKTDGGRRTATSPP---PTTSQT---I 4162 Query: 508 TSSVSTIRQYPVSAQAP 524 S++ + + S AP Sbjct: 4163 ISTIPSTAMHTRSTAAP 4179 Score = 45.4 bits (106), Expect = 3e-04 Identities = 53/212 (25%), Positives = 86/212 (40%), Gaps = 27/212 (12%) Query: 241 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS 300 + S TT T L T+ +H +++ PP + + P +V T+ T S Sbjct: 79 TKSTETTSKAQTDTLTQMMTSTLFSSPSVHNVMETAPPDEMTTSFPSSVTNTLMMT---S 135 Query: 301 PVITTTAAHATDSAL------SRPTLSIQHPPSAAISIQ--RPAQSRDVTTRITLPSHPA 352 IT T + TDS L S P ++A+SI + QSR + R ++ A Sbjct: 136 KTITMTTS--TDSTLGNTEETSTAGTESSTPVTSAVSITAGQEGQSRTTSWRTSIQDTSA 193 Query: 353 LG----------TPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGS----V 398 T + Q T+ +T + + V ++ T PS TA S V Sbjct: 194 SSQNHWTRSTQTTRESQTSTLTHRTTSTPSFSPSVHNVTGTVSQKTSPSGETATSSLCSV 253 Query: 399 SHTQAPTSTIVTMTVPSHSSHATAVTTSNIPV 430 ++T TS +T+T + S+ TS++PV Sbjct: 254 TNTSMMTSEKITVTTSTGSTLGNPGETSSVPV 285 Score = 35.8 bits (81), Expect = 0.22 Identities = 73/295 (24%), Positives = 109/295 (36%), Gaps = 42/295 (14%) Query: 39 STG-LSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVV 97 STG + P +S S G P N S + H++S SS + PV Sbjct: 3898 STGHATPVPVTSTSSASTGDTTPLPVTNASSLSTGHATPL-HVTSPSSASRGDTSTLPVT 3956 Query: 98 ---------VRPYPQVQMLSTHHAVASATPVAVTAPPAHLT-PAVPL------SFSEGLM 141 P P + S + TP+ VT + T A PL S S G Sbjct: 3957 DASSASTGHATPLPLTSLSSV--STGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDT 4014 Query: 142 KPPPKPTMPSR---------PIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVA-TI 191 P P T+PS P+ A S++S P VT T +S + +PV T Sbjct: 4015 TPLPV-TIPSSASSGHTTSLPVTDA--SSVSTGHGTPLPVTSTSSASTGDTTPLPVTDTS 4071 Query: 192 SGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGA-SHLPRGAAAAAVMSSSKVTTVLR 250 S GH + L T++ S PL + + S + G A +SS+ + + Sbjct: 4072 SASTGHATPLPVTDTSSA------STGHATPLPVTSLSSVSTGHATPLAVSSATSASTVS 4125 Query: 251 PTSQLP--NAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVI 303 S L P+++ + + PP TTS I + +T TR+ + I Sbjct: 4126 SDSPLKMETPGMTTPSLKTDGGRRTATSPPPTTSQTIISTIPSTAMHTRSTAAPI 4180 >gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] Length = 2639 Score = 96.3 bits (238), Expect = 1e-19 Identities = 112/497 (22%), Positives = 173/497 (34%), Gaps = 53/497 (10%) Query: 278 PVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQ 337 P+TT+ + P T + + +P+ TTT T + PT Q P Sbjct: 1315 PITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPT----PT-----------GTQTPTT 1359 Query: 338 SRDVTTRITLPSHPALGTPKQQ---LHTMAQKTIFSTGTPVAAATVAPILATNTI-PSAT 393 + TT P+ GT + T T T T T PI T T+ P+ T Sbjct: 1360 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPT 1419 Query: 394 TAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAER 453 G+ + T P +T T+T + A T + I V T T + P Sbjct: 1420 PTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITT 1479 Query: 454 SSLI---PISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSS 510 ++ + P +P P A+ T + P+ P PT P T TP + Sbjct: 1480 TTTVTPTPTPTGTQTPTPTAITTTTTVTPT-PTPTGTQTPTSTPITTTTTV-TPTPTPTG 1537 Query: 511 VSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQG 570 T P+S + TG +T + +T P P TQ Sbjct: 1538 TQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT-----------PTPTGTQT 1586 Query: 571 IQPAPIGTPGIQ---PAPLGTQGIHSATPINTQGL---QPAPMGTQQPQPEGKTSAVVLA 624 I T P P T+ + TPI T P P GTQ P + + ++ Sbjct: 1587 PTTVLITTTTTMTPTPTPTSTKST-TVTPITTTTTVTATPTPTGTQTP------TMIPIS 1639 Query: 625 DGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKS 684 T+ P S P T ++ ++N P + S+P+ S P T+ S Sbjct: 1640 TTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLS 1699 Query: 685 EIH--VSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIP---TMIAAASPPSQPAV 739 + + M + S T + T++ PP+ PP P T ++S P+ V Sbjct: 1700 TLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTV 1759 Query: 740 ALSTIPGAVPITPPITT 756 +T P P++T Sbjct: 1760 QTTTTSAWTPTPTPLST 1776 Score = 84.7 bits (208), Expect = 4e-16 Identities = 115/478 (24%), Positives = 162/478 (33%), Gaps = 52/478 (10%) Query: 371 TGTPVAAATVAPILATNTI-PSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIP 429 T T T PI T T+ P+ T + S T P +T T+T + TT+ I Sbjct: 1304 TTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPIT 1363 Query: 430 VAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFL 489 V T T + P ++ + +P P +T + S P+ Sbjct: 1364 TTTTVTPTPTPTGTQTPTTTPITTTTTV-----TPTPTPTGTQTPT----STPIT---TT 1411 Query: 490 PTYPPSAYPLAAH--TYTPITSSVS-TIRQYPVSAQAPN-SAITAQTGVGVASTVHLNPM 545 T P+ P T TPIT++ + T P QAP +AIT + V T P Sbjct: 1412 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPT----PT 1467 Query: 546 QLMTVDASHARHIQGIQPAPISTQGIQPAPIG-----TPGIQPAPLGTQGIHSATPINTQ 600 T + + P P T P P T P P GTQ ++TPI T Sbjct: 1468 GTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQ-TPTSTPITTT 1526 Query: 601 GL---QPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSAST 657 P P GTQ P P ++ T P P TT + T + T Sbjct: 1527 TTVTPTPTPTGTQTPTPTPIST--------TTTVTPTPTPTGTQTPTTTPITTTTTVTPT 1578 Query: 658 NAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTA 717 P +P ++ + + TP+T + + PT PT Sbjct: 1579 PTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTAT-----PT----PTG 1629 Query: 718 QQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGP 777 Q P IP P+ ST P T PI + + PP + S Sbjct: 1630 TQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSS 1689 Query: 778 PVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMP--TSDLPPGASPR 833 P+ E P I +A P T +P+ + LS P T+ PPG R Sbjct: 1690 PLTESTTLLSTLPPAIEMTSTAPPSTPT---APTTTSGGHTLSPPPSTTTSPPGTPTR 1744 Score = 79.0 bits (193), Expect = 2e-14 Identities = 122/535 (22%), Positives = 177/535 (33%), Gaps = 94/535 (17%) Query: 91 EKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMP 150 E P + V T + S TP +T T P G P P Sbjct: 1309 ENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTT----TTVTPTPTPTGTQTPTTTPITT 1364 Query: 151 SRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQAS------AIPVATISGQQGHPSNLHHI 204 + + P P T + P T T + P + + P+ T + P+ Sbjct: 1365 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQ 1424 Query: 205 MTTNVQMSIIRSNAPGPPLHIGASHLPRGAAA---AAVMSSSKVTTVLRPTSQLPNAATA 261 T ++ + P P P G A A+ ++S VT PT T Sbjct: 1425 TPTTTPITTTTTVTPTPT--------PTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTP 1476 Query: 262 QPAVQHIIHQPI----QSRPP--VTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSAL 315 + P Q+ P +TT+ + P T + T +P+ TTT T + Sbjct: 1477 ITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPT 1536 Query: 316 SRPT--------LSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQ---LHTMA 364 T + P Q P + TT P+ GT + T Sbjct: 1537 GTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTT 1596 Query: 365 QKTIFSTGTPVAAATVAPILATNTIPSATT-AGSVSHTQAPTSTIVTMTV---------- 413 T T T + TV PI T T+ + T G+ + T P ST T+T Sbjct: 1597 TMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTG 1656 Query: 414 -PSHSSHA--TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVA 470 P+H+S A +TTSN P PQ TS + E ++L+ S P A Sbjct: 1657 PPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPL-----TESTTLL-------STLPPA 1704 Query: 471 METRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITA 530 +E S PS P T TS T+ P + +P T Sbjct: 1705 IEMTSTAPPSTP--------------------TAPTTTSGGHTLSPPPSTTTSPPGTPTR 1744 Query: 531 QTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAP 585 T G +S + +Q T A P P+ST P+ I T G++P P Sbjct: 1745 GTTTGSSSAPTPSTVQTTTTSAWTP------TPTPLST----PSIIRTTGLRPYP 1789 Score = 38.9 bits (89), Expect = 0.026 Identities = 34/125 (27%), Positives = 44/125 (35%), Gaps = 16/125 (12%) Query: 708 QPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTV 767 QPT T + P PT T +P P ST P TP TT P P+ T Sbjct: 1299 QPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTP-----TPITTTTTVTPTPTPT- 1352 Query: 768 GGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLP 827 G+ + P V P P + P T TV+P+ PT Sbjct: 1353 -GTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVTPT--------PTPTGTQT 1402 Query: 828 PGASP 832 P ++P Sbjct: 1403 PTSTP 1407 >gi|151301154 mucin 6, gastric [Homo sapiens] Length = 2439 Score = 95.9 bits (237), Expect = 2e-19 Identities = 200/862 (23%), Positives = 313/862 (36%), Gaps = 168/862 (19%) Query: 40 TGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVR 99 TG P+ + +GS P SG S+ + +SL S Sbjct: 1481 TGTIPPPTTLKATGSTHTAPPITPTT--SGTSQAHSSFSTNKTPTSLHSHTSSTH----- 1533 Query: 100 PYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPP 159 +P+V ST + T P AH A +PPP T S P +P Sbjct: 1534 -HPEVTPTSTTTITPNPTSTRTRTPVAHTNSATS-------SRPPPPFTTHSPPTGSSPF 1585 Query: 160 STLSLPPKVPGQVTVTMESSIPQASAIP--VATISGQQGHPSNLHHIMTTNVQMSI---I 214 S+ + T T + + +P V S PS I T+ QM+ I Sbjct: 1586 SSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASI 1645 Query: 215 RSNAPG---PPLHIGASHLPRGAA-----------AAAVMSSSKVTTVLRP-TSQLPNAA 259 S G PP + A+ A A + ++++K +T L TS +A Sbjct: 1646 HSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAE 1705 Query: 260 TAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPT 319 + +I P TS PP V T ++++S T T ++L T Sbjct: 1706 ATSTSTTNITPNP--------TSTGTPPMTVTTSGTSQSRSSFSTAK----TSTSLHSHT 1753 Query: 320 LSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQK-----TIFSTGTP 374 S HP + S TT IT P+H + GT HT + T F+T +P Sbjct: 1754 SSTHHPEVTSTS----------TTSIT-PNHTSTGTRTPVAHTTSATSSRLPTPFTTHSP 1802 Query: 375 VAAAT----VAPILATNTIPSATTAGSVSH-------------TQAPTSTIVTMTVPSHS 417 T P+ AT+ + TT + SH T T + T+ +P+H+ Sbjct: 1803 PTGTTPISSTGPVTATS-FQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHT 1861 Query: 418 SHATAVTTSNIPVAKVVPQQI------THTSPRIQPDYPAERSSLIPISGHRASPNPVAM 471 AT+ + ++P + P THT+P + P S S + S + + Sbjct: 1862 QMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTS-LPY 1920 Query: 472 ETRSDNRPSV-PVQFQYFLP------TYPPSAYPLAAHTY---TPITSSVSTIRQYPVSA 521 T S + P V P P T P A+ +A + TP T+ P S+ Sbjct: 1921 HTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSS 1980 Query: 522 QAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAP---IGT 578 P +A + QT +T + P T +H P ST + P+ I T Sbjct: 1981 TGPMTATSFQT-----TTTYPTPSHPQTTLPTHV--------PPFSTSLVTPSTHTVIIT 2027 Query: 579 PGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPF 638 Q A + IHS P GT P K A G+T Sbjct: 2028 THTQMAT--SASIHST-----------PTGTVPPPTTLK------ATGST---------- 2058 Query: 639 SAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSM 698 AP T SQ+ S+ + A SS S P ++P S +P+T + Sbjct: 2059 HTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPS-------SPITTQL 2111 Query: 699 ETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASP-------PSQPAVALSTIPGAVPIT 751 +S+ T ++ P P+ P+ +++ P S P+V S+ + P+ Sbjct: 2112 PHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVH 2171 Query: 752 PPITTIAAAPPPSVTVGGSLSSV----LGPPVPEIKVK-EEVEPMDIMRP--VSAVPPLA 804 TT+++ S++ + +SV L P P P I P +SA+ P++ Sbjct: 2172 S--TTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLSALLPIS 2229 Query: 805 TNTVS--PSLALLANNLSMPTS 824 T TVS PS L ++ ++ P++ Sbjct: 2230 TVTVSPTPSSHLASSTIAFPST 2251 Score = 90.1 bits (222), Expect = 1e-17 Identities = 184/841 (21%), Positives = 281/841 (33%), Gaps = 166/841 (19%) Query: 138 EGLMKPPPKPTMPSRPIAPAPPSTLSLPPKV-------------------------PGQV 172 EG+ P PT P P P P+T S P +V P Sbjct: 1190 EGVCVPCMPPTTPQPPTTPQLPTTGSRPTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASP 1249 Query: 173 TVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTN--VQMSIIRSNAPGPPLHIGASHL 230 T T S+ P A+ SG+ P+ T+ + +RS A P + + Sbjct: 1250 TQTPLLPATLTSSKPTAS-SGEPPRPTTAVTPQATSGLPPTATLRSTATKPTVTQATTRA 1308 Query: 231 PRGAAAAAVMSSSKVTTVLRPTSQLPNAATA--QPAVQHIIHQPIQSRPPVTTSNAIPPA 288 A+ A S+++ TT R T LP AT+ P + +Q + T+ P Sbjct: 1309 TASTASPATTSTAQSTT--RTTMTLPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTP 1366 Query: 289 VVATVSAT----RAQSPVITTTAAHATDSALSRPTL--SIQHPPSAAISIQR----PAQS 338 T T + P T T T + + P + PP+A + A S Sbjct: 1367 ASTTGPTTPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATS 1426 Query: 339 RDVTTRITLPSHPALGTP------KQQLHTMAQKTIFS-TGTPVAAATVAPILATNTIPS 391 TT PSHP P L T + T+ + T +A + T TIP Sbjct: 1427 FHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPP 1486 Query: 392 ATT--AGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDY 449 TT A +HT P + + T +HSS +T T +++ +HTS P+ Sbjct: 1487 PTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLH---------SHTSSTHHPE- 1536 Query: 450 PAERSSLIPISGHRASPNPVAMETR---------SDNRP-------SVPVQFQYFLPTYP 493 + P S +PNP + TR + +RP S P F T P Sbjct: 1537 ------VTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGP 1590 Query: 494 PSA--------YPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPM 545 +A YP +H T + + V V+ + ++++H P Sbjct: 1591 MTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPT 1650 Query: 546 QLM----TVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHS-------- 593 + T+ A+ + H AP T + A T +HS Sbjct: 1651 GTIPPPTTLKATGSTH-----TAPTMTLTTSGTSQALSSLNTAKTST-SLHSHTSSTHHA 1704 Query: 594 -ATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHS 652 AT +T + P P T P T+ + S S+ A T HS Sbjct: 1705 EATSTSTTNITPNPTSTGTPP-------------MTVTTSGTSQSRSSFSTAKTSTSLHS 1751 Query: 653 QSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQP--- 709 ++ST+ P S+ SI +T P + + ++ + T S P Sbjct: 1752 HTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISS 1811 Query: 710 ----------TIAVPPTAQQPPPTIPTMIAAASP------------PSQPAVALSTIPGA 747 T PT P T+PT + + S P+ +A S + Sbjct: 1812 TGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHS 1871 Query: 748 VP--ITPPITTIAA------APPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSA 799 +P PP TTI A APP + T G+ S + P Sbjct: 1872 MPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHP--E 1929 Query: 800 VPPLATNTVSP------SLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMET 853 V P +T ++P + +A+ S +S LP + P ST G M T Sbjct: 1930 VTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSST--GPMTAT 1987 Query: 854 N 854 + Sbjct: 1988 S 1988 Score = 71.6 bits (174), Expect = 4e-12 Identities = 104/486 (21%), Positives = 182/486 (37%), Gaps = 56/486 (11%) Query: 40 TGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVR 99 TG P+ I +GS P SG S+ +S+SL V Sbjct: 1874 TGTIPPPTTIKATGSTHTAPPMTPTT--SGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVT 1931 Query: 100 PYPQVQMLSTHHAVASATPVAVTAPPA----------HLTPAVPLSFSE-GLMKPPPKPT 148 P + H + + TPVA T + H P FS G M T Sbjct: 1932 PTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSPPTGSSPFSSTGPMTATSFQT 1991 Query: 149 MPSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTN 208 + P P+ P T +LP VP T S + ++ + T Q +++H T Sbjct: 1992 TTTYP-TPSHPQT-TLPTHVPPFST----SLVTPSTHTVIITTHTQMATSASIHSTPTGT 2045 Query: 209 VQ----MSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPA 264 V + S PP+ + S + ++ + ++S ++ + +S LP ++++P Sbjct: 2046 VPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSFSTATAS--SSFISSSSWLPQNSSSRPP 2103 Query: 265 VQHIIHQ---------PIQSRPPVTTSNAIPPAVVATVSA---TRAQSPVITTTAAHATD 312 I Q P+ + +++S + P+ +TVS+ + SP ++ + + Sbjct: 2104 SSPITTQLPHLSSATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSSHSSPQTSSPSVGTSS 2163 Query: 313 SALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL--HTMAQKTIFS 370 S +S P S + S+ + V+ PS PA T + HT++ S Sbjct: 2164 SFVSAPVHSTTLSSGSHSSLSTHPTTASVSASPLFPSSPAASTTIRATLPHTISSPFTLS 2223 Query: 371 TGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTT----- 425 P++ TV+P +++ S S T A T T + S +S +T++TT Sbjct: 2224 ALLPISTVTVSPTPSSHLASSTIAFPSTPRTTASTHTAPAFSSQSTTSRSTSLTTRVPTS 2283 Query: 426 ---------SNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSD 476 + IP + V H P + P SSL + H ++P + + Sbjct: 2284 GFVSLTSGVTGIPTSPVTNLTTRHPGPTLSPTTRFLTSSL---TAHGSTPASAPVSSLGT 2340 Query: 477 NRPSVP 482 P+ P Sbjct: 2341 PTPTSP 2346 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 95.5 bits (236), Expect = 2e-19 Identities = 187/842 (22%), Positives = 286/842 (33%), Gaps = 110/842 (13%) Query: 117 TPVAVTAPPAHLTPAVPLSFSEGLMKPP------PKPTMPSRPIAPAPPST--LSLPPKV 168 TP AVT P +PA F +G PP PK + + P+ P+T +LP Sbjct: 1010 TPPAVTPPSPKGSPAAT-PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPK 1068 Query: 169 PGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGAS 228 G T +++ A P AT +G P+ AP PP S Sbjct: 1069 GGPATPSLKG----APTPPAATPPSPKGGPATPSP------------KGAPMPPAATPPS 1112 Query: 229 HLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPA 288 P+G A + T P S P A P + P + P A PP Sbjct: 1113 --PKGGLATPPHKGAPTTPAATPPS--PKGGLATPPPKGAPTTPAATPPSPKGGLATPPP 1168 Query: 289 VVA-TVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITL 347 A T A SP AT S PT PPS + P+ TT Sbjct: 1169 KGAPTTPAATPPSP----KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1224 Query: 348 PSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAG------SVSHT 401 P P G + +P P T P+AT + H Sbjct: 1225 PPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHK 1284 Query: 402 QAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPIS- 460 AP +VT P ++ P P T SP+ P P + + P + Sbjct: 1285 GAPNPAVVTPPSPKGGP------ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAV 1338 Query: 461 ---GHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQY 517 + +P A S P+ P + PT PP+A P +H P + S R Sbjct: 1339 TPPSPKGTPTLPATTPSSKGGPTTPSSKEG--PT-PPAATP--SHKGGPAMTPPSPKRGP 1393 Query: 518 PVSA----------------QAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGI 561 + + +AP + +T + G S L P + V A Sbjct: 1394 AIPSPKGDPTSPAVIPLSPKKAPATPVTRE-GAATPSKGDLTPPAVTPVSLKKAPATSAP 1452 Query: 562 Q--PAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTS 619 + PA S++G P TP P + + +++ PAPMG Sbjct: 1453 KGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPT------LP 1506 Query: 620 AVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSIL---RKKPA 676 AV+ + + A P S AP AT + + ++ +T AP + P + +K PA Sbjct: 1507 AVIPSSPKEVPATPSSRRDPIAPTATLLSK---KTPATLAPKEALIPPAMTVPSPKKTPA 1563 Query: 677 TDGAK--PKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPP 734 K P + ++P V+ T + + + +PP P P A +PP Sbjct: 1564 IPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELL-IPPAVTSPSPKEAPTPPAVTPP 1622 Query: 735 SQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIK--VKEEVEPMD 792 S + P P +PP+T + P T S++ +G VP+ + + P Sbjct: 1623 SPEKGPATPAPKGTPTSPPVTPSSLKDSP--TSPASVTCKMGATVPQASKGLPAKKGPTA 1680 Query: 793 IMRPVSAVPPLATNTV-SPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVIST------ 845 + + A P +T + +P+ S TS PP + +ST Sbjct: 1681 LKEVLVAPAPESTPIITAPTRKGPQTKKSSATS--PPICPDPSAKNGSKGPLSTVAPAPL 1738 Query: 846 --EEGDMMETNSTDDEKSTAKSLLVKAEKRKSPP------KEYIDEEGVRYVPVRPRPPI 897 + D +T D + K L E + S P ++ + + V P PP+ Sbjct: 1739 LPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPV 1798 Query: 898 TL 899 +L Sbjct: 1799 SL 1800 Score = 83.6 bits (205), Expect = 9e-16 Identities = 155/741 (20%), Positives = 261/741 (35%), Gaps = 75/741 (10%) Query: 92 KQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPS 151 K P YP V + + TP+ VT P + A +F PP + P Sbjct: 416 KSSPNATYHYPLVAQMPV--SSVGTTPLVVTNP-CTIAAAPTTTFEVATCVSPPMSSGPI 472 Query: 152 RPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQM 211 I P P+ L + P P + + + +++ + P+ + PS++ T + Sbjct: 473 SNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDL 532 Query: 212 SIIRSN---APGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAV--Q 266 + ++ AP P G + V ++ K + + TS P + A + Sbjct: 533 QTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAK 592 Query: 267 HIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPP 326 + +P+ P ++ + P V ++ S + S +A S+L PT++ Sbjct: 593 KSLGEPLPIGKPASSMTS-PLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLE 651 Query: 327 SAAISIQRPAQSRDVTTRITLPSHPALGT----PKQQLHTMAQKTIFSTGTPVAAATVAP 382 SA + P ++ +T T S GT PK H + + T+ T P Sbjct: 652 SADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKN--HPVKEGTL----------TTLP 699 Query: 383 ILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTS 442 ++ T + + A S +T AP +T+V S + ++ + P I+HTS Sbjct: 700 LVPTAS-ENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTS 758 Query: 443 PRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAH 502 + P + + SG A+ + T + PS P+ T P +A Sbjct: 759 A-LAPVASSPKECPTEDSGASATASSKGTLTYLADSPS-PLGVSVSPQTKRPPTKKGSAG 816 Query: 503 TYTPITSSVSTIRQYPVSAQ-APNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGI 561 TPI + S + PV A P ++++ Q +T H +P A + + Sbjct: 817 PDTPIGNLSSPVS--PVEASFLPENSLSFQGSKDSPATTH-SPTPPSPKGAPTPSAVTPL 873 Query: 562 QPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQ------------PAPMGT 609 P ++ + P TP + P +G + P L PAP G Sbjct: 874 SPKGVT---LPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGI 930 Query: 610 Q-QPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRP 668 P P+G + A +P P + +P + + PA +P P Sbjct: 931 PASPSPKGAPTPP-----AATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPA---TPSP 982 Query: 669 SILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMI 728 PA PK ATP S + P PP+ + P P Sbjct: 983 KGAPTPPAATPPSPKG----GPATP--------SPKGAPTPPAVTPPSPKGSPAATPFPK 1030 Query: 729 AAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEV 788 A++PP+ + P A P+ T AA PS G + S+ G P P Sbjct: 1031 GASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSP 1090 Query: 789 E-------PMDIMRPVSAVPP 802 + P P +A PP Sbjct: 1091 KGGPATPSPKGAPMPPAATPP 1111 Score = 82.0 bits (201), Expect = 3e-15 Identities = 219/932 (23%), Positives = 312/932 (33%), Gaps = 140/932 (15%) Query: 36 GAPSTGLSQAPSQIANSGSAGLIN----PAATVNDESGRDSEVSAREHMSSSSSLQSREE 91 GAP+T + PS + L PAAT G + S + Sbjct: 1055 GAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKG------------A 1102 Query: 92 KQEPVVVRPYPQVQMLSTHHAVASATPVAV---------TAPP--AHLTPAV-PLSFSEG 139 P P P+ + + H A TP A T PP A TPA P S G Sbjct: 1103 PMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1162 Query: 140 LMKPPPK--PTMPSR-PIAP-----------APPSTLSLPPKVPGQVTVTMESSIPQASA 185 L PPPK PT P+ P +P AP + + PP G + P A Sbjct: 1163 LATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1222 Query: 186 IPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLP-------RGAAAAA 238 + G PS TT P P GA P +G A Sbjct: 1223 ATPPSPKGGLATPSP-KGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATP 1281 Query: 239 VMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRP-PVTTSNAIPPAVVATVSATR 297 + V+ P S AT+ P + P + P P + PP T A Sbjct: 1282 PHKGAPNPAVVTPPSPKGGPATSPP--KGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVT 1339 Query: 298 AQSPVITTTAAHATDSALSRPTLSIQH----PPSAAISIQR-PAQSRDVTTRITLPSHPA 352 SP T T T S+ PT PP+A S + PA + R PA Sbjct: 1340 PPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKR-----GPA 1394 Query: 353 LGTPKQQLHTMAQKTIF---STGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIV 409 + +PK + A + + TPV A + P A T S+ A ++ Sbjct: 1395 IPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKG 1454 Query: 410 TMTVPSHSSHATA-VTTSNIPVAKVVPQQI-THTSPRIQPDYPAERSSLIPISGHRASPN 467 PS T T P P+Q+ T +SP+ P PA + + +SP Sbjct: 1455 GPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPK 1514 Query: 468 PVAMETRSDNRPSVPVQFQYFLPTYP---------PSAYPLAAHTYTPITSSVSTIRQYP 518 V S P P T P A + + TP + P Sbjct: 1515 EVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATP 1574 Query: 519 VSAQAPNS-AITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIG 577 S +A + A+T T G S P +L+ A + + AP P+P Sbjct: 1575 SSKEASSPPAVTPSTYKGAPS-----PKELLIPPAVTS---PSPKEAPTPPAVTPPSPEK 1626 Query: 578 TPGIQPAPLGTQGIHSATPINTQGLQPAP------MGTQQPQPE----GKTSAVVLADGA 627 P PAP GT TP + + +P MG PQ K L + Sbjct: 1627 GPAT-PAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKE-V 1684 Query: 628 TIVANPISNPFSAAPAATTVVQTHSQSAST-------------NAPAQGSSPRPSILRKK 674 + P S P AP QT SA++ P +P P + +K Sbjct: 1685 LVAPAPESTPIITAPTRKGP-QTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQK 1743 Query: 675 PATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPP 734 ++ AK K H S P+ S P A P P ++ AA SPP Sbjct: 1744 DSSKTAKGKDASH-SPKGPLAPPESKAST-----PLTAAAFEKVLPKPESASVSAAPSPP 1797 Query: 735 SQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIM 794 V+L P VP PP + P V L S P P + +E+ P+ Sbjct: 1798 ----VSLPLAPSPVPTLPPKQQFLPSSPGLV-----LESPSKPLAPADE--DELLPL--- 1843 Query: 795 RPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETN 854 +PP + P ++L N + ++ +P K+P + + S E D E+ Sbjct: 1844 -----IPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESV 1898 Query: 855 STDDEKSTAKSLLVKAEKRKSPPKEYIDEEGV 886 +E+ + ++ +A+ + IDEE V Sbjct: 1899 PELEEQDSTQATTQQAQLAAAAE---IDEEPV 1927 Score = 76.6 bits (187), Expect = 1e-13 Identities = 183/797 (22%), Positives = 296/797 (37%), Gaps = 121/797 (15%) Query: 95 PVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPI 154 P + PQ Q + ++SA ++VTA P +P S + P + P Sbjct: 10 PATEQELPQPQAETAVLPMSSA--LSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPF 67 Query: 155 APAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSII 214 P+P + S P +VP PQ+S+ + P+ L +++ + + + Sbjct: 68 -PSPSTIASTPLEVP----------FPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAAL 116 Query: 215 RSNAP--GPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPT--SQLPNAATAQPAVQHIIH 270 +P P L S A A S + ++ P + P+ A A+ + Sbjct: 117 ALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLS 176 Query: 271 QPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATD--SALSRPTLSI-QHPPS 327 PI P T N +P VV T + +++T H +++ S+ Q P+ Sbjct: 177 APIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPT 236 Query: 328 AAISIQRPAQSRDVTTRITL--PSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILA 385 ++I P Q +D T L P +P + K + A ++ + PV + Sbjct: 237 TTLAIASP-QVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTS------- 288 Query: 386 TNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSH--------ATAVTTSNIPVAKVVPQQ 437 S TAG + P S + + P H S T + + P K + Sbjct: 289 -----SQKTAGPNTPPDFPIS-LGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTI--S 340 Query: 438 ITHTSPRIQPDYPAERSSLIPI-SGHRASPNPVA----METRSDNRPSVPVQFQYFLPTY 492 + H+S YP++RS + P+ S + P VA + D PS T Sbjct: 341 VDHSSTGAS--YPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSI-----TC 393 Query: 493 PPS-------AYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPM 545 PS ++ L+ T + SS + YP+ AQ P S+ VG V NP Sbjct: 394 SPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSS------VGTTPLVVTNPC 447 Query: 546 QLMTVDASHARHIQGIQP----APIST-QGIQPAPIGTPGIQPAPLGTQGIHSATPINTQ 600 + + + P PIS + PA + + P TQ AT + Sbjct: 448 TIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQ---VATTLRI- 503 Query: 601 GLQPAPMGTQQPQPE---GKTSAVVLA-----DGATIVANPISNPFSAAPAATTVVQTHS 652 P+ P PE S+V++ D T+ A+ PFS A A T + + Sbjct: 504 -----PVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPT 558 Query: 653 -----QSASTNAPA-QGSSPRPSILRKKPATDGAK------PKSEIHVSMATPVTV--SM 698 Q+A N+P+ Q +S P I AT K P + SM +P+ V S Sbjct: 559 VLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSA 618 Query: 699 ETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPA-VALSTIPGAVPITPPIT-- 755 + + P A P + PT+ A + PA VA +T G T + Sbjct: 619 SVIKTDSYAGPDSAGP--LLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPF 676 Query: 756 ---TIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSL 812 T++ AP G+L+++ P VP V P P + PLAT ++P + Sbjct: 677 LEGTVSLAPKNHPVKEGTLTTL--PLVPTASENCPVAPS----PQNTCAPLATLVLAPEI 730 Query: 813 ALLANNLSMPTSDLPPG 829 + S+P + PPG Sbjct: 731 PKSVPSPSLPPAGTPPG 747 Score = 42.0 bits (97), Expect = 0.003 Identities = 95/428 (22%), Positives = 150/428 (35%), Gaps = 58/428 (13%) Query: 37 APSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPV 96 AP+ L + + LI PA TV + + +E ++ SS +E P Sbjct: 1528 APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSS----KEASSPP 1583 Query: 97 VVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAP 156 V P ST+ S P + PPA +P S PP T PS P Sbjct: 1584 AVTP-------STYKGAPS--PKELLIPPAVTSP------SPKEAPTPPAVTPPSPEKGP 1628 Query: 157 A-------------PPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHH 203 A PS+L P P VT M +++PQAS + ++G P+ L Sbjct: 1629 ATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQAS----KGLPAKKG-PTALKE 1683 Query: 204 IMTTNVQMS--II-----------RSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLR 250 ++ S II +S+A PP+ S + ++ + + V + Sbjct: 1684 VLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQK 1743 Query: 251 PTSQLPNAATAQPAVQHIIHQP-IQSRPPVTTS---NAIPPAVVATVSATRAQSPVITTT 306 +S+ A + + + P ++ P+T + +P A+VSA A SP ++ Sbjct: 1744 DSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSA--APSPPVSLP 1801 Query: 307 AAHATDSALSRPTLSIQHPPSAAI-SIQRPAQSRDVTTRITL-PSHPALGTPKQQLHTMA 364 A + L + P + S +P D + L P P G Q + Sbjct: 1802 LAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVN 1861 Query: 365 QKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVT 424 T S G PV + + N S T + S T + A A Sbjct: 1862 MPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAE 1921 Query: 425 TSNIPVAK 432 PV+K Sbjct: 1922 IDEEPVSK 1929 >gi|146219843 Snf2-related CBP activator protein [Homo sapiens] Length = 3230 Score = 92.4 bits (228), Expect = 2e-18 Identities = 161/788 (20%), Positives = 264/788 (33%), Gaps = 161/788 (20%) Query: 100 PYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPP 159 P P + + T A +P PP + PL+ G PP T S A A Sbjct: 1100 PTPTLSLKPTPPAPVRLSPAP---PPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATT 1156 Query: 160 STLSLPPKVPGQVTVT--MESSIPQASAI-----------PVA----------------- 189 + + P P ++ ++ M++ +P + PVA Sbjct: 1157 TAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKL 1216 Query: 190 TISGQQ------GHPSNL-------------HHIMTTNVQMSIIRSNAPGP---PLHIGA 227 T++G Q G P L HH+++ +++I++ AP P P+ + Sbjct: 1217 TLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLP 1276 Query: 228 SHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIP- 286 S P A +S + PT + N + V+ + PP+ + P Sbjct: 1277 SSTPSTTPAPTGLSLPLAANQVPPT-MVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPS 1335 Query: 287 ---PAVV---ATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRD 340 PAV+ T++ R +P + T A L RP L + H PS +S P + Sbjct: 1336 SGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAA-- 1393 Query: 341 VTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSH 400 I+ P H P M +PV++ P+ ++ I TT + + Sbjct: 1394 -PLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPA- 1451 Query: 401 TQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPIS 460 AP + ++ + +S +T+ P+A VVP P + P + +S + + Sbjct: 1452 -SAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPA--APGPPSLAPSGASPSASALTLG 1508 Query: 461 -------------GHRASPNPVAMETRSDNRPSVPVQFQYFLPT------YP--PSAYPL 499 GH P + N P +P +P P+ P Sbjct: 1509 LATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPA 1568 Query: 500 AAHTYTPITSSVSTIRQYPVSAQAPNSAITAQT---------------GVGVASTVHLNP 544 A P +S+ + AP +AI A + G P Sbjct: 1569 QASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTP 1628 Query: 545 MQLMTVDASHARHIQGIQP--------APISTQGIQPAPIGTPGIQPAPLGTQGIHSATP 596 + +M ++ + P AP STQ + PAP+ +P PA T + A Sbjct: 1629 VPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALA 1688 Query: 597 INTQGLQPAP---MGTQQPQPEGKTSAVVLADGATIVANPI------------------- 634 G P+ +GT PQ T + L +++V P Sbjct: 1689 PTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSL 1748 Query: 635 --------SNPFSAAPAATTVVQTHSQSASTNAPAQ------GSSPRPSILRKKPATDGA 680 ++P APA T + S SAS APA +P P++ T Sbjct: 1749 APAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLAL 1808 Query: 681 KPKSE-----------IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIA 729 P S + S A P+ V+M + + D+P + PP+ T Sbjct: 1809 APASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFG 1868 Query: 730 AASPPSQP 737 P QP Sbjct: 1869 GPRPRRQP 1876 Score = 86.7 bits (213), Expect = 1e-16 Identities = 209/883 (23%), Positives = 298/883 (33%), Gaps = 154/883 (17%) Query: 100 PYPQVQMLSTHHAVASATPVAVTAP----PAHLTPAVPLSFSEGLMKP-----------P 144 P PQV S + + A P + A P L P P S S + P P Sbjct: 1040 PVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRP 1099 Query: 145 PKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVA-------------TI 191 P PT+ +P PAP PP PG ++ ++P P A T Sbjct: 1100 PTPTLSLKPTPPAPVRLSPAPP--PGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTT 1157 Query: 192 SGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIG--ASHLPRGAAAAA-------VMSS 242 + P+ I++ ++Q + G + IG AS R A A + Sbjct: 1158 AVPAPTPAPQRLILSPDMQARL----PSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQG 1213 Query: 243 SKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPV 302 +K+T QL +P ++++H S A++ V+ T +PV Sbjct: 1214 NKLTLTGAQVRQLA-VGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPV 1272 Query: 303 I----TTTAAHATDSALSRPTLSIQHPPS-----AAISIQRPAQSRDVTTRITLPSHPAL 353 +T + + LS P + Q PP+ + I RD T + P PA Sbjct: 1273 SVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVP-PLAPAP 1331 Query: 354 GTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTV 413 P S+G P A P L +P+ T + PT T+V + Sbjct: 1332 RPP-------------SSGLP-AVLNPRPTLTPGRLPTPTLG--TARAPMPTPTLVRPLL 1375 Query: 414 PSHSSHATAVTTSNIPVAKVVPQQITHTSP-RIQPDYPAERSSLIPISGHRASPNPVAME 472 S + V+ S A +T +SP + P SS +PI +PV+ Sbjct: 1376 KLVHSPSPEVSASAPGAAP-----LTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSST 1430 Query: 473 TRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVS--------TIRQYPVSAQAP 524 S+P+ LP P++ PL P+T S S T PV AP Sbjct: 1431 VSVPLSSSLPISVPTTLPA--PASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAP 1488 Query: 525 NSAITAQTGVGV-ASTVHLNPMQLMTVDASHAR-HIQGIQPAPISTQGIQP--APIGTPG 580 A +G AS + L ++ +S H + P G+ AP +P Sbjct: 1489 GPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPV 1548 Query: 581 IQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVA--NPISNPF 638 + PA SA PAP P S + A + A I P Sbjct: 1549 LVPASALASPFPSAP-------NPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPS 1601 Query: 639 SAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSM 698 A P A V S A AP SS P + +T G S V TPV Sbjct: 1602 PAPPLAPLPVLAPSPGA---APVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPS 1658 Query: 699 ETVSNQNNDQPTIAVPPTAQQP----PPTIPTMIAAASPPSQ-------------PAVAL 741 T + P+ P + Q P PT+ S PSQ P L Sbjct: 1659 STQTMLPAPVPSPLPSPASTQTLALAPALAPTL--GGSSPSQTLSLGTGNPQGPFPTQTL 1716 Query: 742 STIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVP 801 S P + + P T++ AP P + +LS PP + P S V Sbjct: 1717 SLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPP---------------LAPASPVG 1761 Query: 802 PLATNTV-----SPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNST 856 P +T+ S S +LLA S+ T L P P P Q + + ST Sbjct: 1762 PAPAHTLTLAPASSSASLLA-PASVQTLTLSPAPVPTLGPAAAQTL-------ALAPAST 1813 Query: 857 DDEKSTAKSLLVKAEKRKSPPKEYIDEEGVRYVPVRPRPPITL 899 S A SL+V A P + +PV P TL Sbjct: 1814 QSPASQASSLVVSASGAAPLPVTMVSR-----LPVSKDEPDTL 1851 Score = 82.4 bits (202), Expect = 2e-15 Identities = 189/798 (23%), Positives = 284/798 (35%), Gaps = 108/798 (13%) Query: 97 VVRPYPQVQ---MLSTHHAVASATPVAVTAPP-----AHLTPA-VPLSFSEGLM---KPP 144 +++P P+ + ++ ++ A PV V PP A TP VP LM P Sbjct: 997 MLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPA 1056 Query: 145 PKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPS-NLHH 203 P +P A PP + LPP P S+PQ P+ +SG P+ L Sbjct: 1057 GPPLIP----ASRPPGPVLLPPLQPNS------GSLPQVLPSPLGVLSGTSRPPTPTLSL 1106 Query: 204 IMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQP 263 T + + + PG + +P G +++ TT T+ A T P Sbjct: 1107 KPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPT--P 1164 Query: 264 AVQHIIHQP-IQSRPPVTTSNAIPPAVVATVS--ATRAQSPVITTTAAHATDSAL--SRP 318 A Q +I P +Q+R +P V ++ A+ AQ PV + + ++ Sbjct: 1165 APQRLILSPDMQAR--------LPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKL 1216 Query: 319 TLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAA 378 TL+ A+ RP Q V H + P A + P Sbjct: 1217 TLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQP-------AHVALIQAVAPTPGP 1269 Query: 379 TVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQI 438 T +L PS+T S T APT +++P ++ +N V K+V +Q Sbjct: 1270 TPVSVL-----PSSTP----STTPAPTG----LSLPLAANQVPPTMVNNTGVVKIVVRQA 1316 Query: 439 THTS-PRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAY 497 + P PA R P SG A NP T + R P P P+ Sbjct: 1317 PRDGLTPVPPLAPAPRP---PSSGLPAVLNP--RPTLTPGRLPTPTLGTARAPMPTPTLV 1371 Query: 498 -PLAAHTYTPITSSVSTIRQYPVSAQAPNSA-ITAQTGVGVASTVH---LNPMQL----- 547 PL ++P VSA AP +A +T + + V S++ +PM + Sbjct: 1372 RPLLKLVHSPSPE---------VSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSP 1422 Query: 548 MTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQP--APL-----GTQGIHSATPINTQ 600 + S + PIS PAP P P APL G + S TP Sbjct: 1423 LASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTP-PLA 1481 Query: 601 GLQPAPMGTQQPQPEGKT-SAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSA-STN 658 + PA G P G + SA L G + S+ P +H ST Sbjct: 1482 PVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTV 1541 Query: 659 APAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQ 718 APA P+ P P + S+ P + + + ++ P A Sbjct: 1542 APACSPVLVPASALASPFPSAPNP-APAQASLLAPASSASQALAT-----------PLAP 1589 Query: 719 QPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPP 778 P + + +PP P L+ PGA P+ T PS T G SL+S P Sbjct: 1590 MAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVP 1649 Query: 779 VPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLA-LLANNL--SMPTSDLPPGASPRKK 835 P + + PV + P +T + +LA LA L S P+ L G + Sbjct: 1650 APTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQG 1709 Query: 836 PRKQQHVISTEEGDMMET 853 P Q + T ++ T Sbjct: 1710 PFPTQTLSLTPASSLVPT 1727 Score = 45.1 bits (105), Expect = 4e-04 Identities = 73/348 (20%), Positives = 128/348 (36%), Gaps = 56/348 (16%) Query: 396 GSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQP---DYPAE 452 G+ + TQ T P S+H T TT+ P +++ +PR +P PA Sbjct: 2401 GARAETQGANHT------PVISAHQTRSTTTP-PRCSPARERVPRPAPRPRPTPASAPAA 2453 Query: 453 RSSLIPISGHR----ASPNPVAMETRSDNRPSVPVQFQYFLP-------TYPPSAYPLAA 501 +L+P+ ++PNP+ + PS P Q +P T PP+ P A Sbjct: 2454 IPALVPVPVSAPVPISAPNPITI-LPVHILPSPPPPSQ--IPPCSSPACTPPPACTPPPA 2510 Query: 502 HTYTPITSSVSTIRQ--------YPVSAQAPNSAITAQTGVGVASTVHLNP--MQLMTVD 551 HT P + + T P+SA N + + + + +P ++L +V Sbjct: 2511 HTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVA 2570 Query: 552 ASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQ 611 +S + + P + ++ P+ + P + P T P G +Q Sbjct: 2571 SSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTP--------SAPSLTLEAGSIPNGQEQ 2622 Query: 612 PQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNA---PAQGSSPRP 668 P+ A+G T+ P + + ++ +AS P + Sbjct: 2623 EAPDS-------AEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSE 2675 Query: 669 SILRKK-PATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPP 715 + K P + KP+ + +A P T S T S + P+ A PP Sbjct: 2676 ELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEG---PSPARPP 2720 Score = 43.1 bits (100), Expect = 0.001 Identities = 182/942 (19%), Positives = 305/942 (32%), Gaps = 148/942 (15%) Query: 7 PQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINPAATVND 66 P AG+ + G GGG + S++ P T +S+ + A Sbjct: 2364 PGAGDESSCGTGGGTHRR----SKKAKAPERPGTRVSER------------LRGARAETQ 2407 Query: 67 ESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAP-- 124 + +SA + S+++ + ++ P P+ S A+ + PV V+AP Sbjct: 2408 GANHTPVISAHQTRSTTTPPRCSPARERVPRPAPRPRPTPASAPAAIPALVPVPVSAPVP 2467 Query: 125 ----------PAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPP--KVPGQV 172 P H+ P+ PPP P A PP + PP P Sbjct: 2468 ISAPNPITILPVHILPS----------PPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQ 2517 Query: 173 TVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPR 232 T + S P P IS TN+ + + P L A P Sbjct: 2518 TCLVTPSSPLLLGPPSVPISAS-----------VTNLPLGL----RPEAELCAQALASPE 2562 Query: 233 GAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVAT 292 A+V SS + L P L A V S P +T P Sbjct: 2563 SLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQ 2622 Query: 293 VSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAIS--IQRPAQSRDVTTRITLPSH 350 + A+ +T + ++ PPSAA +Q P ++ + +T Sbjct: 2623 EAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKT 2682 Query: 351 PALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVT 410 P K Q A+ ST + ++ P A P T+ V T Sbjct: 2683 PTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARP--PRRRTSADVEIRGQGTGR--- 2737 Query: 411 MTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIP-ISGHRASPNPV 469 P + + VV ++ R Q S+L+P +S ASP Sbjct: 2738 ---PGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQ---RGAASTLVPGVSETSASPGSP 2791 Query: 470 AMETRSDNRPSVPV------QFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQA 523 ++ + S S P+ LPT P + H +T S + Sbjct: 2792 SVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGG--------GSPEN 2843 Query: 524 PNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPIS-----TQGIQPAP--- 575 + A+ A T V P + + S A +G+ AP S T G P P Sbjct: 2844 GDGALLAITPPAVKRRRGRPPKK----NRSPADAGRGVDEAPSSTLKGKTNGADPVPGPE 2899 Query: 576 ---IGTPGIQ------PAPLGTQGIHS----ATPINTQGLQPAPMGTQQPQPEGKTSAVV 622 + P ++ P PLG Q +H +P+ + P P P +SA Sbjct: 2900 TLIVADPVLEPQLIPGPQPLGPQPVHRPNPLLSPVEKRRRGRPPKARDLPIPGTISSA-- 2957 Query: 623 LADG-ATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAK 681 DG + P +P P +V + A+T S+ P R +P + Sbjct: 2958 -GDGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTISTSPPKRKRGRPPKNPPS 3016 Query: 682 PKSEIHVSMATPVTVSMETVSNQNNDQPT-------IAVPPTAQQPPPTIPTMIAAA--- 731 P+ + T +E+ QP + +P + + A Sbjct: 3017 PRPSQLPVLDRDSTSVLESCGLGRRRQPQGQGESEGSSSDEDGSRPLTRLARLRLEAEGM 3076 Query: 732 -SPPSQPAVALSTI----------PGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVP 780 S ++ ++ I PG + +TPP+ ++ + GSL VP Sbjct: 3077 RGRKSGGSMVVAVIQDDLDLADSGPGGLELTPPVVSLTPKLRSTRLRPGSL-------VP 3129 Query: 781 EIKVKEEVEPMDIMRPVSAVPPLA-------TNTVSPSLALLANNLSMPTSDLPPGASPR 833 ++ E++ PV P LA + + P ++ + + +PR Sbjct: 3130 PLET-EKLPRKRAGAPVGGSPGLAKRGRLQPPSPLGPEGSVEESEAEASGEEEEGDGTPR 3188 Query: 834 KKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKS 875 ++P ++ V +T +GD S+ ++ + K K+ Sbjct: 3189 RRPGPRRLVGTTNQGDQRILRSSAPPSLAGPAVSHRGRKAKT 3230 >gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens] Length = 5765 Score = 85.1 bits (209), Expect = 3e-16 Identities = 167/737 (22%), Positives = 253/737 (34%), Gaps = 94/737 (12%) Query: 115 SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTV 174 +++P APPA T AVP + SEGL P T+ + S P VPG T Sbjct: 1637 TSSPGLTRAPPASTT-AVP-TLSEGLTSPRYTSTLGTATTGGPTTPAGSTEPTVPGVAT- 1693 Query: 175 TMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGA 234 S++P SA+P T S PS + T + S R AS P Sbjct: 1694 ---STLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSRARPTGTAST----ASKEPLTT 1746 Query: 235 AAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVT----------TSNA 284 + A + +S+++T TS T P Q P ++ Sbjct: 1747 SLAPTL-TSELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQPKCEWTEWFDVDFPTSG 1805 Query: 285 IPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPP---SAAISIQRPAQSRDV 341 + + T RA + A + P +SI + ++ ++ D Sbjct: 1806 VAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQ 1865 Query: 342 TTRITL--PSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVS 399 T R + + + H + ST TP + IL T +ATT S Sbjct: 1866 TGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGTTWIL-TKPTTTATTTASTG 1924 Query: 400 HTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPI 459 T PTST+ T P T TT + +K P +SP PA RS+ Sbjct: 1925 STATPTSTL--RTAPPPKVLTTTATTPTVTSSKATPS----SSPGTATALPALRSTATTP 1978 Query: 460 SGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPV 519 + +P P + + R S + T PS+ P AHT T +T++ +T Sbjct: 1979 TATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATT------ 2032 Query: 520 SAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTP 579 A S T + G A T + +T G P +P Sbjct: 2033 -TGATGSVATPSSTPGTAHTTKV---------------------PTTTTTGFTATPSSSP 2070 Query: 580 GIQPAPLGTQGIHSATPINTQGLQPAPM---GTQQPQPEGKTSAVVLADGATIVANPISN 636 G P I + T T+G P GT T+ +A G+ + + Sbjct: 2071 GTALTP--PVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQ 2128 Query: 637 PFSAAPAATTVVQTHSQSASTNAPAQ--GSSPRPSILRKKPATDGA-----KPKSEIHVS 689 P+ TT T + + ST P+ G++P P +L T A P S + + Sbjct: 2129 TSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSNTVTPSSALGTT 2188 Query: 690 MATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVP 749 PV +M T + ++PP++ P T+ T +A+ S I G Sbjct: 2189 HTPPVPNTMATTHGR-------SLPPSS---PHTVRTAWTSAT---------SGILGTTH 2229 Query: 750 ITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRP-VSAVPPLATNTV 808 IT P T + + + L P P + E P + T T Sbjct: 2230 ITEPSTVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATA 2289 Query: 809 SPSLALLANNL-SMPTS 824 +PS + L S PTS Sbjct: 2290 TPSKTRTSTLLPSSPTS 2306 Score = 84.3 bits (207), Expect = 5e-16 Identities = 178/819 (21%), Positives = 282/819 (34%), Gaps = 139/819 (16%) Query: 95 PVVVRPYPQVQMLSTHHAVASATPVAVTAPPA-HLTPAVPLSFSEGLMKPPPKPTM---- 149 P V+ +++ A S++P TA PA T P + S + P P ++ Sbjct: 1939 PKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATS---VTPIPSSSLGTTW 1995 Query: 150 -----PSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHI 204 + P A +T S P+ TV ++ + VAT S G Sbjct: 1996 TRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVP 2055 Query: 205 MTTNVQMSIIRSNAPG----PPLHIGASHLP--RGAAA--AAVMSSSKVTTVLRPTSQLP 256 TT + S++PG PP+ I + P RG+ +++ ++ TVL T+ Sbjct: 2056 TTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTT-- 2113 Query: 257 NAATAQPAVQHIIHQPIQSRPPVTTS-------------------NAIPPAVVATVSATR 297 AT A Q + P +TT+ IPP + T + Sbjct: 2114 TVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPA 2173 Query: 298 AQSPVITTTAAHATDSALSRP-TLSIQH----PPSAAISIQRPAQSRDV----TTRITLP 348 A S +T ++A T P T++ H PPS+ +++ S TT IT P Sbjct: 2174 ATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEP 2233 Query: 349 SHPALGTPKQQLHTMAQKT-IFSTGTPVAAATVAPILATNTIPSATTAGS-VSHTQAPTS 406 S T T T S+ P + T +P T P TTA S + T P+ Sbjct: 2234 STVTSHTLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSK 2293 Query: 407 TIVTMTVPSHSSHA--TAVTTSNIPVAKVVPQQITHTSPRIQPD-YPAERSSLIPISGHR 463 T + +PS + A T V T + + ++ P P + S I +G Sbjct: 2294 TRTSTLLPSSPTSAPITTVVTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGA 2353 Query: 464 ASPNPVAMETRSDNRPSVPVQ----------------------------FQYFL------ 489 P+ +E R+ +P VP++ F Y + Sbjct: 2354 VCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCN 2413 Query: 490 ----PTYP-------PSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITA--QTGVGV 536 P+ P PS+ P T +T++ +T +A ++ T T Sbjct: 2414 YGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPST 2473 Query: 537 ASTVHLNPMQLMTVDASHAR----HIQGIQPAPISTQGIQPAPIGTPGIQPA-PLGTQGI 591 +TV + T ++ A H+ P T + P +PG A P Sbjct: 2474 TATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSS-KATPFSSPGTATALPALRSTA 2532 Query: 592 HSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTH 651 + T + + + +GT + T+ AT + P + S T Sbjct: 2533 TTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGA 2592 Query: 652 SQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPT- 710 + S +T + G++ +L A P S + PV +S T T Sbjct: 2593 TGSVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTP 2652 Query: 711 IAVPPTAQQPP--PTIPTMIAAAS-------------PPSQPAVAL-----------STI 744 ++P T P T T +A S PPS A S+ Sbjct: 2653 SSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSST 2712 Query: 745 PGAVPITPPITTIA---AAPPPSVTVGGSLSSVLGPPVP 780 PG PI P +TT A AA +VT +L + PPVP Sbjct: 2713 PGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVP 2751 Score = 82.8 bits (203), Expect = 2e-15 Identities = 138/600 (23%), Positives = 207/600 (34%), Gaps = 98/600 (16%) Query: 231 PRGAAAAAVMSSSKVTTVL--RPTSQLPNAATAQPAVQHIIHQPIQSRPP-VTTSNAIPP 287 P ++ A S+ T +L + T+ A T A+ P + PP V TS A P Sbjct: 2978 PATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPS--STPGTAPPPKVLTSTATTP 3035 Query: 288 AVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITL 347 ++ AT + SP TT T +A S PS + + T T+ Sbjct: 3036 TATSS-KATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATM 3094 Query: 348 PSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPI-------LATNTIPSATTAGSVSH 400 + TP + HT T +T T ++ P + T +ATT + Sbjct: 3095 STIHPSSTP-ETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGP 3153 Query: 401 TQAPT------------STIVTMTVP------SHSSHATA----VTTSNIPVAKVVPQQI 438 T P+ ST T+TVP + S+ ATA V TS V+ + Sbjct: 3154 TATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRA 3213 Query: 439 T-HTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAY 497 T +SP PA RS+ + + P + + R S + T PS+ Sbjct: 3214 TPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSST 3273 Query: 498 PLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARH 557 P HT T +T++ +T R A S T + G A T + Sbjct: 3274 PETVHTSTVLTTTTTTTR-------ATGSVATPSSTPGTAHTTKV--------------- 3311 Query: 558 IQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPM---GTQQPQP 614 +T G P +PG P I + T T+G P GT Sbjct: 3312 ------PTTTTTGFTATPSSSPGTALTP--PVWISTTTTPTTRGSTVTPSSIPGTTHTAT 3363 Query: 615 EGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKK 674 T+ +A G+ + + P+ TT T + + ST P+ Sbjct: 3364 VLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPS------------- 3410 Query: 675 PATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQP-PPTIPTMIAAASP 733 +T G P + + AT + TV+ P+ A+ T P P T T + P Sbjct: 3411 -STPGTTPIPPVLTTTATTPAATSSTVT------PSSALGTTHTPPVPNTTATTHGRSLP 3463 Query: 734 PSQP-------AVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKE 786 PS P A S I G IT P T + P + + + L P P + E Sbjct: 3464 PSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTE 3523 Score = 80.9 bits (198), Expect = 6e-15 Identities = 164/742 (22%), Positives = 260/742 (35%), Gaps = 105/742 (14%) Query: 114 ASATPV---AVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPG 170 A+A P T P A A+P S + T P+ ++ A PS S P V Sbjct: 2522 ATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPS--STPETVHT 2579 Query: 171 QVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGP----PLHIG 226 +T ++ A+ VAT S G + TT + S++PG P+ I Sbjct: 2580 STVLTTTATTTGATG-SVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWIS 2638 Query: 227 ASHLP--RGAAA--AAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTT- 281 + P RG+ +++ ++ TVL T+ AT A Q + P +TT Sbjct: 2639 TTTTPTTRGSTVTPSSIPGTTHTPTVL--TTTTTTVATGSMATPSSSTQTSGTPPSLTTT 2696 Query: 282 ------------------SNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRP----- 318 + IPP + T + A S +T ++A T P Sbjct: 2697 ATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTAT 2756 Query: 319 ----TLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKT-IFSTGT 373 +LS P + + TT IT PS TP T T S+ Sbjct: 2757 THGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPH 2816 Query: 374 PVAAATVAPILATNTIPSATTAGS-VSHTQAPTSTIVTMTVPSHSSHA--TAVTTSNIPV 430 P + T +P T P T A S + T P+ T + +PS + A T V T Sbjct: 2817 PSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEP 2876 Query: 431 AKVVPQQITHTSPRIQPD-YPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQ----- 484 + + ++ P P + S I +G P+ +E R+ +P VP++ Sbjct: 2877 QCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQV 2936 Query: 485 -----------------------FQYFLPTY------PPSAYPLAAHTYTPITSSVSTIR 515 F Y + + PS P + T TP ++ +T Sbjct: 2937 VECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPST-PATSSTATPSSTPGTTWI 2995 Query: 516 QYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAP 575 + A +A T T + ++ P +++T A+ + S + P Sbjct: 2996 LTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLP 3055 Query: 576 IGT--------PGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQ--PEGKTSAVVLAD 625 + T P P T G P T A M T P PE ++ VL Sbjct: 3056 VLTSTATKSTATSFTPIPSFTLGTTGTLPEQTT-TPMATMSTIHPSSTPETTHTSTVLTT 3114 Query: 626 GATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSE 685 AT S ++ TT + T +A+T A G + PS P T + Sbjct: 3115 KATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPS---STPGTTWILTEPS 3171 Query: 686 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP 745 ++ P T S T S+ T+ V + T PT+I++ + PS + +P Sbjct: 3172 TTATVTVP-TGSTATASSTRATAGTLKVLTST----ATTPTVISSRATPSSSPGTATALP 3226 Query: 746 G--AVPITPPITTIAAAPPPSV 765 + TP T++ A P S+ Sbjct: 3227 ALRSTATTPTATSVTAIPSSSL 3248 Score = 78.2 bits (191), Expect = 4e-14 Identities = 180/834 (21%), Positives = 278/834 (33%), Gaps = 129/834 (15%) Query: 114 ASATPV---AVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPG 170 A+A P T P A A+P S + T P+ ++ A PS+ P+ Sbjct: 3779 ATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSST---PETAH 3835 Query: 171 QVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPG----PPLHIG 226 TV ++ + VAT S G TT ++ S++PG PP+ I Sbjct: 3836 TSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWIS 3895 Query: 227 ASHLPRGAAAAAVMSSSKVTTVLRP--TSQLPNAATAQPAVQHIIHQPIQSRPPVTTS-- 282 + P + + SS TT T+ AT A Q + P + T+ Sbjct: 3896 TTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTAT 3955 Query: 283 -----------------NAIPPAVVATVSATRAQSPVITTTAAHATDSALSRP------- 318 IPP + T + A S +T ++A T P Sbjct: 3956 TITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVPNTTATTH 4015 Query: 319 --TLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKT-IFSTGTPV 375 +LS P + + TT IT PS TP T T S+ P Sbjct: 4016 GRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPALSSPHPS 4075 Query: 376 AAATVAPILATNTIPSATTAGS-VSHTQAPTSTIVTMTVPSHSSHA--TAVTTSNIPVAK 432 + T +P T P TTA S + T P+ T + +PS + A T V T+ Sbjct: 4076 SRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQC 4135 Query: 433 VVPQQITHTSPRIQPD-YPAERSSLIPISGHRASPNPVAMETRSDNRPSVPV-------- 483 + + ++ P P + S I +G P+ +E R+ +P VP+ Sbjct: 4136 AWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVE 4195 Query: 484 ------------------------QFQYFLPTYP--PSAYPLAAHTYTPITSSVSTIRQY 517 + + F Y PS P + T P ++ +T Sbjct: 4196 CSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPST-PATSSTAMPSSTPGTTWILT 4254 Query: 518 PVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIG 577 ++ A +A T T ++ P +++T A+ + S + P+ Sbjct: 4255 ELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVL 4314 Query: 578 T--------PGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQ--PEGKTSAVVLADGA 627 T + P P T G P T A M T P PE ++ VL A Sbjct: 4315 TSTATKSTATSVTPIPSSTLGTTGTLPEQTT-TPVATMSTIHPSSTPETTHTSTVLTTKA 4373 Query: 628 TIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPS-------ILRKKPAT--- 677 T S ++ TT + T +A+T A G + PS IL + T Sbjct: 4374 TTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATT 4433 Query: 678 -----DGAKPKSE-------IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIP 725 A P S S VTV + + ++ Q T P + T P Sbjct: 4434 TASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVS--TTATTP 4491 Query: 726 TMIAAASPPSQPAVALSTIPG--AVPITPPITTIAAAPPPSV-TVGGSLSSVLGPPVPEI 782 T+ ++ + PS + +P + TP T+ A P S+ T LS P Sbjct: 4492 TVTSSKATPSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTP----- 4546 Query: 783 KVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNL-SMPTSDLPPGASPRKK 835 M P S + T+TV + A S+ T PG + K Sbjct: 4547 -----TATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTK 4595 Score = 74.3 bits (181), Expect = 6e-13 Identities = 115/511 (22%), Positives = 179/511 (35%), Gaps = 59/511 (11%) Query: 277 PPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPA 336 P V TS A P ++ AT + SP TT T +A S+ PS+ + Sbjct: 4282 PKVLTSPATTPTATSS-KATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTL 4340 Query: 337 QSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPI-------LATNTI 389 + T T+ + TP + HT T +T T ++T P + T Sbjct: 4341 PEQTTTPVATMSTIHPSSTP-ETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELT 4399 Query: 390 PSATTAGSVSHTQAPTST---------IVTMTVPSHSSHATAVTTSNIPVAKVVPQQITH 440 +ATT + T P+ST + T + S+ +TA +S ++ + T Sbjct: 4400 TAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTT 4459 Query: 441 TSPRIQPDYPAERSSLIPISG--HRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYP 498 + + A SS +G H ++ T S PS LP +A Sbjct: 4460 ATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATT 4519 Query: 499 LAAHTYTPI-TSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARH 557 A ++T I +SS+ T P + ++ T TVH + + T + A Sbjct: 4520 PTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGA-- 4577 Query: 558 IQGIQPAPIS--------------TQGIQPAPIGTPGIQPAP---LGTQGIHSATPINTQ 600 G P S T G P +PG P + T + T T Sbjct: 4578 -TGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTS 4636 Query: 601 GLQPAPM---GTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSAST 657 G P GT T+ +A G+ + + P+ TT T + + ST Sbjct: 4637 GSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGST 4696 Query: 658 NAPAQ--GSSPRPSILRK---KPATDGAKPKSEIHVSMAT--PVTVSMETVSNQNNDQP- 709 P+ G++P +L PA +K S AT PV S T S + P Sbjct: 4697 TNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPI 4756 Query: 710 -------TIAVPPTAQQPPPTIPTMIAAASP 733 T VP P T+ T+ +++P Sbjct: 4757 PSSTLWTTWTVPAQTTTPMSTMSTIHTSSTP 4787 Score = 73.9 bits (180), Expect = 7e-13 Identities = 174/782 (22%), Positives = 275/782 (35%), Gaps = 81/782 (10%) Query: 108 STHHAVASATPV---AVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSL 164 S+ A+A P T P A A+P S + T P+ ++ A PS S Sbjct: 3216 SSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPS--ST 3273 Query: 165 PPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPG---- 220 P V +T ++ +A+ VAT S G TT + S++PG Sbjct: 3274 PETVHTSTVLTTTTTTTRATG-SVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALT 3332 Query: 221 PPLHIGASHLP--RGAAA--AAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSR 276 PP+ I + P RG+ +++ ++ TVL T+ AT A Q + Sbjct: 3333 PPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTT--TVATGSMATPSSSTQTSGTP 3390 Query: 277 PPVTTS-------------------NAIPPAVVATVSATRAQSPVITTTAAHATDSALSR 317 P +TT+ IPP + T + A S +T ++A T Sbjct: 3391 PSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPV 3450 Query: 318 P-TLSIQH----PPSAAISIQRPAQSRDV----TTRITLPSHPALGTPKQQLHTMAQKT- 367 P T + H PPS+ +++ S TT IT PS TP T T Sbjct: 3451 PNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTP 3510 Query: 368 IFSTGTPVAAATVAPILATNTIPSATTAGS-VSHTQAPTSTIVTMTVPSHSSHA--TAVT 424 S+ P + T +P T P T S + T P+ T + +PS + A T V Sbjct: 3511 ALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVV 3570 Query: 425 TSNIPVAKVVPQQITHTSPRIQPDY-PAERSSLIPISGHRASPNPVAMETRSDNRPSVPV 483 T+ + + ++ P P + S I +G P+ +E R+ +P VP+ Sbjct: 3571 TTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPL 3630 Query: 484 QFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSA------QAPNSAITAQTGVGVA 537 + + + L + Y + P++ T+ T + Sbjct: 3631 R-ELGQVVECSLDFGLVCRNREQV-GKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSS 3688 Query: 538 STVHLNPMQLMTVDASHARHIQGIQPAPISTQGI-----QPAPIGTPGIQPAPLGTQGIH 592 + + +T A+ G P ST G +P+ T + P G+ Sbjct: 3689 TPGTTWILTKLTTTATTTEST-GSTATPSSTPGTTWILTEPSTTATVTV---PTGS---- 3740 Query: 593 SATPINTQGLQPAP-MGTQQPQPEGKTS-AVVLADGATIVANPISNPFSAAPAATTVVQT 650 +AT +TQ P + T P +S A + T A P + P AT+ Sbjct: 3741 TATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAI 3800 Query: 651 HSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPT 710 S S T + P+ AT + P++ H S T +T + T + Sbjct: 3801 PSSSLGTTWTRLSQTTTPTATMST-ATPSSTPETA-HTS--TVLTTTATTTRATGSVATP 3856 Query: 711 IAVPPTAQQPP-PTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGG 769 + P TA PT T +P S P A + T P T+ + P SV Sbjct: 3857 SSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPGTT 3916 Query: 770 SLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPP--LATNTVSPSLALLANNLSMP-TSDL 826 +VL + P + S PP + T T + N S P T+ + Sbjct: 3917 HTPTVLTTTTTTVATGSMATPSSSTQ-TSGTPPSLITTATTITATGSTTNPSSTPGTTPI 3975 Query: 827 PP 828 PP Sbjct: 3976 PP 3977 Score = 70.1 bits (170), Expect = 1e-11 Identities = 110/458 (24%), Positives = 175/458 (38%), Gaps = 72/458 (15%) Query: 243 SKVTTVLRPTSQLPNAAT--AQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS 300 +++TT T + AT + P I+ + P T + +P AT S+T+A + Sbjct: 2440 TELTTTATTTESTGSTATPSSTPGTTWIL-----TEPSTTATVTVPTGSTATASSTQATA 2494 Query: 301 --PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQ 358 P ++TTA T ++ S +A +++ A + T+ +PS +LGT Sbjct: 2495 GTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPS-SSLGTTWT 2553 Query: 359 QLH-------TMAQKTIFSTGTPVAAATVAPILATNT------IPSATTAGSVSHTQAPT 405 +L TM+ T ST V +TV AT T ++T G+ T+ T Sbjct: 2554 RLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKVLT 2613 Query: 406 STIVTMTVPSHSSHATA-------------------VTTSNIPVAKVVPQQITHTSPRIQ 446 +T T SS TA VT S+IP P +T T+ + Sbjct: 2614 TTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTV- 2672 Query: 447 PDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTP 506 A S P S + S P ++ T + + T PS+ P TP Sbjct: 2673 ----ATGSMATPSSSTQTSGTPPSLTTTATTITATG-------STTNPSSTP----GTTP 2717 Query: 507 ITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPI 566 I ++T P A +S +T + +G T H P+ T +H R + P + Sbjct: 2718 IPPVLTTTATTPA---ATSSTVTPSSALG---TTHTPPVP-NTTATTHGRSLSPSSPHTV 2770 Query: 567 ST--QGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLA 624 T +GT I GT +AT TQ PA P P +T+ + Sbjct: 2771 RTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHSTPA---LSSPHPSSRTTESPPS 2827 Query: 625 DGATIVANPISNPFSAAPAATTVVQTHS--QSASTNAP 660 G T + + + A A + +T + S+ T+AP Sbjct: 2828 PGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTSAP 2865 Score = 70.1 bits (170), Expect = 1e-11 Identities = 175/758 (23%), Positives = 259/758 (34%), Gaps = 122/758 (16%) Query: 108 STHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPK--------PTMPSRPIAPAPP 159 +T A S + T AH T VP + + G P P S P Sbjct: 3288 TTTRATGSVATPSSTPGTAHTTK-VPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTR 3346 Query: 160 STLSLPPKVPGQ-----VTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSII 214 + P +PG V T +++ S ++ + G P +L TT Sbjct: 3347 GSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSL----TTTATTITA 3402 Query: 215 RSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQ 274 + P G + +P A ++ +TV P+S L T P+ Sbjct: 3403 TGSTTNPSSTPGTTPIPPVLTTTATTPAATSSTVT-PSSALGTTHTP----------PVP 3451 Query: 275 SRPPVTTSNAIPPAVVATVSA--TRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISI 332 + T ++PP+ TV T A S ++ TT H T+ P+ H P+A S Sbjct: 3452 NTTATTHGRSLPPSSPHTVRTAWTSATSGILGTT--HITE-----PSTVTSHTPAATTST 3504 Query: 333 QR---PAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTP--VAAATVAPILATN 387 + PA S + T S P+ GT HT +T TP +T+ P T+ Sbjct: 3505 TQHSTPALSSPHPSSRTTESPPSPGTTTPG-HTRGTSRTTATATPSKTRTSTLLPSSPTS 3563 Query: 388 TIPSATTAGSVSHTQAPTSTIVTMTVPSHS-SHATAVTTSNIPVA--KVVPQQI-THTSP 443 P T + Q S + + P S T SNI A V Q + Sbjct: 3564 A-PITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRA 3622 Query: 444 RIQPDYPAERSSLIP--------ISGHRASPNPVAMETRSDNR---------PSVPVQFQ 486 + QP P + + +R M + R PS P Sbjct: 3623 QAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSS 3682 Query: 487 YFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQ--TGVGVASTVHLNP 544 T PS+ P T +T++ +T +A ++ T T +TV + Sbjct: 3683 ----TATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPT 3738 Query: 545 MQLMTVDASHAR----HIQGIQPAPISTQGIQPAPIGTPGIQ---PAPLGTQGIHSATPI 597 T ++ A H+ P T + P +PG PA T +AT Sbjct: 3739 GSTATASSTQATAGTPHVSTTATTPTVTSS-KATPFSSPGTATALPALRSTATTPTATSF 3797 Query: 598 N--------------TQGLQP-APMGTQQPQ--PEGKTSAVVLADGATI------VANPI 634 +Q P A M T P PE ++ VL AT VA P Sbjct: 3798 TAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPS 3857 Query: 635 SNPFSAAPAATTVVQTHSQSASTNAPAQ--GSSPRPSI---LRKKPATDGAK-PKSEIHV 688 S P A TT V T + + T P+ G++ P + P T G+ S + Sbjct: 3858 STP---GTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSVPG 3914 Query: 689 SMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPP---TIPTMIAAASPPSQPAVALSTIP 745 + TP ++ T + T + PP T T I A + P S+ P Sbjct: 3915 TTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTATTITATGSTTNP----SSTP 3970 Query: 746 GAVPITPPITTIA---AAPPPSVTVGGSLSSVLGPPVP 780 G PI P +TT A AA +VT +L + PPVP Sbjct: 3971 GTTPIPPVLTTTATTPAATSSTVTPSSALGTTHTPPVP 4008 Score = 69.7 bits (169), Expect = 1e-11 Identities = 167/715 (23%), Positives = 240/715 (33%), Gaps = 91/715 (12%) Query: 115 SATPVAVTAPPAHLTPAVPLSF-SEGLMKPPPKP--------TMPSRPIAPAPPS---TL 162 S TP A T H TPA+ S + PP P T SR A A PS T Sbjct: 4052 SHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTS 4111 Query: 163 SLPPKVPGQV---TVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMS--IIRSN 217 +L P P TV PQ + S PS +N++ + + Sbjct: 4112 TLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQ 4171 Query: 218 APGPPLHIGASH-LPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHII-----HQ 271 G A +P G V S V R Q+ + H Sbjct: 4172 PLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHC 4231 Query: 272 PIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAIS 331 P P T+S A+P + T + TTTA+ + +A T PP S Sbjct: 4232 P---STPATSSTAMPSSTPGTTWILTELTTTATTTASTGS-TATPSSTPGTAPPPKVLTS 4287 Query: 332 IQRPAQSRDVTT-RITLPSHPALGTPKQQLHTMAQK------------TIFSTGTPVAAA 378 PA + T+ + T S P T L + A K T+ +TGT + Sbjct: 4288 ---PATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGT-LPEQ 4343 Query: 379 TVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQI 438 T P+ +TI ++T + TST++T + + ++ T S+ P + ++ Sbjct: 4344 TTTPVATMSTIHPSSTPETTH-----TSTVLTTKATTTRATSSTSTPSSTPGTTWILTEL 4398 Query: 439 THTSPRIQPDYPAERSSLIP----ISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPP 494 T + P S P I + T S PS + L Sbjct: 4399 TTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWIL----- 4453 Query: 495 SAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASH 554 P T T T S +T +A P+ + TA T V S+ T A Sbjct: 4454 -TEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPT-VTSSKATPSSSPGTATALP 4511 Query: 555 ARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQP 614 A P S I + +GT T+ + TP T + Sbjct: 4512 ALRSTATTPTATSFTAIPSSSLGT-------TWTRLSQTTTPTATMSTATPSSTPETVHT 4564 Query: 615 EGKTSAVVLADGAT-IVANPISNPFSA----APAATTVVQTHSQSASTN---APAQGSSP 666 +A GAT VA P S P +A P TT T + S+S P S Sbjct: 4565 STVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWIST 4624 Query: 667 RPSILRKKPATDGA--KPKS------EIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQ 718 + P T G+ P S V T TV+ +++ ++ T PP+ Sbjct: 4625 TTTPTTTTPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSL- 4683 Query: 719 QPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSS 773 T T I A + P S+ PG PITP +T+ A P + + S SS Sbjct: 4684 ---TTTATTITATGSTTNP----SSTPGTTPITPVLTSTATTPAATSSKATSSSS 4731 Score = 66.2 bits (160), Expect = 1e-10 Identities = 102/421 (24%), Positives = 156/421 (37%), Gaps = 54/421 (12%) Query: 273 IQSRPPVTTSNAIPPAVVATVSAT--RAQSPVITTTAAHATDSALSRPTLSIQHPPSAAI 330 I ++P T + AT ++T A P + TT A S+ T S + A+ Sbjct: 1909 ILTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATAL 1968 Query: 331 SIQRPAQSRDVTTRITLPSHPALGTPKQQLH-----TMAQKTIFSTGTPVAAATVAPILA 385 R + T +T +LGT +L T T + TP A T + A Sbjct: 1969 PALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTA 2028 Query: 386 TNTIPSAT--------TAGSVSHTQAPTSTIVTMTVPSHSSHATAVT------TSNIPVA 431 T T AT T G+ T+ PT+T T SS TA+T T+ P Sbjct: 2029 TATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTT 2088 Query: 432 K---VVPQQI---THTSPRIQPDYP--AERSSLIPISGHRASPNPVAMETRSDNRPSVPV 483 + V P I THT+ + A S P S + S P ++ T + + Sbjct: 2089 RGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATG- 2147 Query: 484 QFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLN 543 T PS+ P TPI ++T P A ++ +T + +G T H Sbjct: 2148 ------STTNPSSTP----GTTPIPPVLTTTATTPA---ATSNTVTPSSALG---TTHTP 2191 Query: 544 PMQLMTVDASHARHIQGIQPAPISTQGIQPAP--IGTPGIQPAPLGTQGIHSATPINTQG 601 P+ T+ +H R + P + T +GT I T +AT TQ Sbjct: 2192 PVP-NTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQH 2250 Query: 602 LQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHS--QSASTNA 659 PA P P +T+ + G T + + + A A + +T + S+ T+A Sbjct: 2251 STPA---LSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSA 2307 Query: 660 P 660 P Sbjct: 2308 P 2308 Score = 65.9 bits (159), Expect = 2e-10 Identities = 115/521 (22%), Positives = 187/521 (35%), Gaps = 95/521 (18%) Query: 243 SKVTTVLRPTSQLPNAAT--AQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS 300 +K+TT T + AT + P I+ + P T + +P AT S+T+A + Sbjct: 3697 TKLTTTATTTESTGSTATPSSTPGTTWIL-----TEPSTTATVTVPTGSTATASSTQATA 3751 Query: 301 --PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQ 358 P ++TTA T ++ S +A +++ A + T+ +PS +LGT Sbjct: 3752 GTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSS-SLGTTWT 3810 Query: 359 QLHTMAQKTIFSTGTPVAA-ATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHS 417 +L T TP A +T P T ++T + + T T ++ T + + Sbjct: 3811 RLS--------QTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGT 3862 Query: 418 SHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDN 477 +H T V T+ V P T+ R P ++ T Sbjct: 3863 AHTTKVPTTTTTGFTVTPSSSPGTA--------------------RTPPVWISTTTTPTT 3902 Query: 478 RPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVA 537 S T PS+ P HT T +T++ +T+ + A S+ T +G Sbjct: 3903 SGS----------TVTPSSVPGTTHTPTVLTTTTTTVA---TGSMATPSSSTQTSGT--- 3946 Query: 538 STVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAP--LGTQGIHSAT 595 P L+T + I+ G P TPG P P L T A Sbjct: 3947 ------PPSLITTATT------------ITATGSTTNPSSTPGTTPIPPVLTTTATTPAA 3988 Query: 596 PINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSA 655 +T A +GT P T+A G ++ S+P + A T+ + Sbjct: 3989 TSSTVTPSSA-LGTTHTPPVPNTTATT--HGRSLSP---SSPHTVRTAWTSATSGTLGTT 4042 Query: 656 STNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPP 715 P+ G+S P+ AT G S +S P S++ + P Sbjct: 4043 HITEPSTGTSHTPA------ATTGTTQHSTPALSSPHP--------SSRTTESPPSPGTT 4088 Query: 716 TAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITT 756 T T T A ++ + L + P + PIT +TT Sbjct: 4089 TPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTT 4129 Score = 62.4 bits (150), Expect = 2e-09 Identities = 109/477 (22%), Positives = 163/477 (34%), Gaps = 38/477 (7%) Query: 361 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA 420 H + ST TP + IL T +ATT + T P+ST T P Sbjct: 2973 HCPSTPATSSTATPSSTPGTTWILTEQTT-AATTTATTGSTAIPSSTPGTAPPPK----- 3026 Query: 421 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS 480 +T+ P A + + +SPR P S+ + +P P + P Sbjct: 3027 VLTSTATTPTA-TSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPE 3085 Query: 481 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV 540 + T PS+ P HT T +T+ +T R S+ + S+ T + T Sbjct: 3086 QTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRA--TSSMSTPSSTPGTTWILTELTT 3143 Query: 541 HLNPMQLMTVDASHARHIQGIQPAPISTQGI-----QPAPIGTPGIQPAPLGTQGIHSAT 595 A+ G P ST G +P+ T + P G+ S+T Sbjct: 3144 -----------AATTTAATGPTATPSSTPGTTWILTEPSTTATVTV---PTGSTATASST 3189 Query: 596 PINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSA 655 T G T + A + T A P + P AT+V S S Sbjct: 3190 RA-TAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSL 3248 Query: 656 STNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPP 715 T + P+ AT + P++ +H S T +T + T + + P Sbjct: 3249 GTAWTRLSQTTTPTATMST-ATPSSTPET-VHTS--TVLTTTTTTTRATGSVATPSSTPG 3304 Query: 716 TAQQPP-PTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSV 774 TA PT T A+P S P AL+ T P T + P S+ ++V Sbjct: 3305 TAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATV 3364 Query: 775 LGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLAL--LANNLSMP-TSDLPP 828 L + P + S PP T T + A N S P T+ +PP Sbjct: 3365 LTTTTTTVATGSMATPSSSTQ-TSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPP 3420 Score = 60.5 bits (145), Expect = 8e-09 Identities = 158/689 (22%), Positives = 228/689 (33%), Gaps = 135/689 (19%) Query: 251 PTSQLPNAATAQPAVQHIIHQPIQS----RPPVTTSNAIPPAVVATVSATRAQSPVITTT 306 PT++L A T QP S R P ++ A+P S + TT Sbjct: 1615 PTTELETATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLGTATT 1674 Query: 307 AAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHP-ALGTPK-QQLHTMA 364 T + + PT+ P A S + TR LP +LGT + Q T+A Sbjct: 1675 GGPTTPAGSTEPTV-----PGVATST--------LPTRSALPGTTGSLGTWRPSQPPTLA 1721 Query: 365 QKTIF-STGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAV 423 T+ S P A+ A T + T +S +QA TST T T S T Sbjct: 1722 PTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETT---MSPLTNT 1778 Query: 424 TTSNIPVAKVVPQQITHTSPRIQ------PDYPA--------ERSSLIPISGHRASPNPV 469 TTS Q T P+ + D+P E I +G + P Sbjct: 1779 TTS---------QGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPK 1829 Query: 470 AMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAIT 529 ++E R++N P V + +T S+ T N T Sbjct: 1830 SIECRAENYPEVSID-----------------QVGQVLTCSLET------GLTCKNEDQT 1866 Query: 530 AQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQ 589 + + + N L D SH PA ST P GT I P T Sbjct: 1867 GRFNM----CFNYNVRVLCCDDYSHCPST----PATSSTATPSSTP-GTTWILTKPTTTA 1917 Query: 590 GI-----HSATPINTQGLQPAP--MGTQQPQPEGKTS-AVVLADGATIVANPISNPFSAA 641 +ATP +T P P + T P +S A + T A P + Sbjct: 1918 TTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATT 1977 Query: 642 PAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETV 701 P AT+V S S T + P+ AT + P++ H S T +T + T Sbjct: 1978 PTATSVTPIPSSSLGTTWTRLSQTTTPTATMST-ATPSSTPETA-HTS--TVLTATATTT 2033 Query: 702 SNQNNDQPTIAVPPTAQQPP-PTIPTMIAAASPPSQPAVAL------------------- 741 + + P TA PT T A+P S P AL Sbjct: 2034 GATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTV 2093 Query: 742 --STIPG----AVPITPPITTIA-------------AAPPPSVTVGGSLSSVLGPPVPEI 782 S+IPG A +T TT+A + PPS+T + + G Sbjct: 2094 TPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTNPS 2153 Query: 783 KVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHV 842 ++ + P +NTV+PS A L + P + R P H Sbjct: 2154 STPGTTPIPPVLTTTATTPAATSNTVTPSSA-LGTTHTPPVPNTMATTHGRSLPPSSPHT 2212 Query: 843 I-----STEEGDMMETNSTDDEKSTAKSL 866 + S G + T+ T+ T+ +L Sbjct: 2213 VRTAWTSATSGILGTTHITEPSTVTSHTL 2241 Score = 59.3 bits (142), Expect = 2e-08 Identities = 120/532 (22%), Positives = 187/532 (35%), Gaps = 86/532 (16%) Query: 39 STGLSQAPSQIANSGSAGLI---NPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEP 95 STG + PS + G+ ++ + ATV +G + S+ + + + + + Sbjct: 4436 STGSTATPS--STPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTV 4493 Query: 96 VVVRPYPQVQMLSTHHAVASATPV---AVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSR 152 + P S+ A+A P T P A A+P S + T P+ Sbjct: 4494 TSSKATP-----SSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTA 4548 Query: 153 PIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMS 212 ++ A PS S P V +T ++ A+ VAT S G TT + Sbjct: 4549 TMSTATPS--STPETVHTSTVLTATATTTGATG-SVATPSSTPGTAHTTKVPTTTTTGFT 4605 Query: 213 IIRSNAPG----PPLHIGASHLPR-----------------GAAAAAVMSSSKVTTVLRP 251 S++PG PP+ I + P G A + ++ TTV Sbjct: 4606 ATPSSSPGTALTPPVWISTTTTPTTTTPTTSGSTVTPSSIPGTTHTARVLTTTTTTVATG 4665 Query: 252 TSQLPNAATAQPAVQHIIHQPI------------QSRP------PVTTSNAIPPAVVATV 293 + P+++T + S P PV TS A PA ++ Sbjct: 4666 SMATPSSSTQTSGTPPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSS- 4724 Query: 294 SATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPAL 353 AT + SP TT T +A S PS+ + ++ T T+ + Sbjct: 4725 KATSSSSPRTATTLPVLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMSTIHTS 4784 Query: 354 GTPKQQLHTMAQKTIFSTGTPVAAATVAP--------ILATNTIPSATTAGS-----VSH 400 TP + HT T +T T +T P IL T + TTA + +S Sbjct: 4785 STP-ETTHTSTVLTTTATMTRATNSTATPSSTLGTTRILTELTTTATTTAATGSTATLSS 4843 Query: 401 TQAPT------STIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERS 454 T T STI T+ VP+ S+ + T KVV T P + Sbjct: 4844 TPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMAT---------MPTATA 4894 Query: 455 SLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTP 506 S +P S + A+ S SV L T P+ +P ++H TP Sbjct: 4895 STVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTGFP-SSHFSTP 4945 Score = 57.8 bits (138), Expect = 5e-08 Identities = 168/757 (22%), Positives = 245/757 (32%), Gaps = 94/757 (12%) Query: 130 PAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSL-----PPKVPGQVTVTMESSIPQAS 184 P+ P + S + P T + +T S P PG + E S Sbjct: 2418 PSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATV 2477 Query: 185 AIPV---ATISGQQGHPSNLHHIMTTNVQMSIIRSNA-----PGPPLHIGA----SHLPR 232 +P AT S Q + H+ TT ++ S A PG + A + P Sbjct: 2478 TVPTGSTATASSTQA-TAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPT 2536 Query: 233 GAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVAT 292 + A+ SSS TT R + AT A P + V TS + T Sbjct: 2537 ATSFTAIPSSSLGTTWTRLSQTTTPTATMSTAT------PSSTPETVHTSTVLTTTATTT 2590 Query: 293 VSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPA 352 + +P T AH T L+ T PS++ R ++T T + + Sbjct: 2591 GATGSVATPSSTPGTAHTT-KVLTTTTTGFTATPSSSPGTARTLPVW-ISTTTTPTTRGS 2648 Query: 353 LGTPKQQLHTMAQKTIFSTGTPVAA----ATVAPILATNTIP-----SATTAGSVSHTQA 403 TP T T+ +T T A AT + T+ P +ATT + T Sbjct: 2649 TVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTITATGSTTN 2708 Query: 404 PTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQI---THTSPRIQPDYPAERSSLIPIS 460 P+ST T +P + T TT + V P THT P SL P S Sbjct: 2709 PSSTPGTTPIPPVLT--TTATTPAATSSTVTPSSALGTTHTPPVPNTTATTHGRSLSPSS 2766 Query: 461 GHRA-----SPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIR 515 H S + T PS ++ P+A TP SS Sbjct: 2767 PHTVRTAWTSATSGTLGTTHITEPSTGT-------SHTPAATTGTTQHSTPALSSPHPSS 2819 Query: 516 QYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPIST---QGIQ 572 + S +P + T +T P + T + API+T G + Sbjct: 2820 RTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLPSSPTS----APITTVVTMGCE 2875 Query: 573 PAPIGTPGIQ---PAPLGTQGIHSATPINTQGLQPA----PMGTQ---QPQPE------G 616 P + + P P G G T N + A P+G + Q QP G Sbjct: 2876 PQCAWSEWLDYSYPMP-GPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELG 2934 Query: 617 KTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPA 676 + L G F V + + PA S+ PS + Sbjct: 2935 QVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPS------S 2988 Query: 677 TDGAKPKSEIHVSMATPVTVSMETVSNQ-NNDQPTIAVPPTAQQPPPTIPTMIAAASPPS 735 T G + I T T + T S + P A PP T PT ++ + S Sbjct: 2989 TPGT---TWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSS 3045 Query: 736 QPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMR 795 +T+P T + P PS T+G + +PE + + M + Sbjct: 3046 SSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTT------GTLPE-QTTTPMATMSTIH 3098 Query: 796 PVSAVPPLATNTVSPSLALLAN-NLSMPTSDLPPGAS 831 P S T+TV + A SM T PG + Sbjct: 3099 PSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTT 3135 Score = 55.5 bits (132), Expect = 3e-07 Identities = 114/508 (22%), Positives = 171/508 (33%), Gaps = 74/508 (14%) Query: 130 PAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSL-----PPKVPGQVTVTMESSIPQAS 184 P+ P + S P T + +T S P PG + E S Sbjct: 3675 PSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATV 3734 Query: 185 AIPV---ATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMS 241 +P AT S Q + H+ TT ++ S A A+ LP + A + Sbjct: 3735 TVPTGSTATASSTQA-TAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPT 3793 Query: 242 SSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSP 301 ++ T + P+S L T + P T S A P + T S Sbjct: 3794 ATSFTAI--PSSSLGTTWTRLSQT---------TTPTATMSTATPSSTPETAHT----ST 3838 Query: 302 VITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLH 361 V+TTTA +R T S+ P S + TT T+ + GT + Sbjct: 3839 VLTTTAT------TTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTP-- 3890 Query: 362 TMAQKTIFSTGTPVAA-ATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA 420 I +T TP + +TV P +++P T +V T T +M PS S+ Sbjct: 3891 ---PVWISTTTTPTTSGSTVTP----SSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQT 3943 Query: 421 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS 480 + S I A + + T+P P +P P + T + + Sbjct: 3944 SGTPPSLITTATTITATGSTTNPSSTPG---------------TTPIPPVLTTTATTPAA 3988 Query: 481 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGV--GVAS 538 T PS+ HT P+ ++ +T +S +P++ TA T G Sbjct: 3989 TS-------STVTPSSALGTTHT-PPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLG 4040 Query: 539 TVHLNPMQLMT--VDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLG--TQGIHSA 594 T H+ T A+ Q PA S P P P G T G +A Sbjct: 4041 TTHITEPSTGTSHTPAATTGTTQHSTPALSS-----PHPSSRTTESPPSPGTTTPGHTTA 4095 Query: 595 TPINTQGLQPAPMGTQQPQPEGKTSAVV 622 T T P+ T P TSA + Sbjct: 4096 TSRTTATATPSKTRTSTLLPSSPTSAPI 4123 Score = 54.7 bits (130), Expect = 5e-07 Identities = 108/478 (22%), Positives = 157/478 (32%), Gaps = 53/478 (11%) Query: 107 LSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKP----------TMPSRPIAP 156 +ST H S+TP T A + + P P T + A Sbjct: 3094 MSTIHP--SSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAAT 3151 Query: 157 APPSTLSLPPKVPGQVTVTMESSIPQASAIPV---ATISGQQGHPSNLHHIMTTNVQMSI 213 P +T P PG + E S +P AT S + L + +T ++ Sbjct: 3152 GPTAT---PSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTV 3208 Query: 214 IRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNA-----ATAQPAVQHI 268 I S A A+ LP + A +++ VT + P+S L A T P Sbjct: 3209 ISSRATPSSSPGTATALPALRSTATTPTATSVTAI--PSSSLGTAWTRLSQTTTPTATMS 3266 Query: 269 IHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSA 328 P + V TS + T + +P T AH T + T P S+ Sbjct: 3267 TATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSS 3326 Query: 329 -AISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVA-PILAT 386 ++ P TT T S + HT T +T T VA ++A P +T Sbjct: 3327 PGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLT--TTTTTVATGSMATPSSST 3384 Query: 387 NT-------IPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQ-- 437 T +ATT + T P+ST T +P + T TT + V P Sbjct: 3385 QTSGTPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLT--TTATTPAATSSTVTPSSAL 3442 Query: 438 -ITHTSPRIQPDYPAERSSLIPISGHR-----ASPNPVAMETRSDNRPSVPVQFQYFLPT 491 THT P SL P S H S + T PS + + Sbjct: 3443 GTTHTPPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPST-------VTS 3495 Query: 492 YPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMT 549 + P+A TP SS + S +P + T +T P + T Sbjct: 3496 HTPAATTSTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRT 3553 Score = 32.0 bits (71), Expect = 3.1 Identities = 46/202 (22%), Positives = 78/202 (38%), Gaps = 24/202 (11%) Query: 639 SAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSM 698 + P TT ++T + +T A S+P+P+ P A P S T ++ Sbjct: 1610 ATTPPPTTELET---ATTTTTQALFSTPQPT---SSPGLTRAPPAS----------TTAV 1653 Query: 699 ETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP--GAVP-ITPPIT 755 T+S + TA PT P A ++ P+ P VA ST+P A+P T + Sbjct: 1654 PTLSEGLTSPRYTSTLGTATTGGPTTP---AGSTEPTVPGVATSTLPTRSALPGTTGSLG 1710 Query: 756 TIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALL 815 T + PP++ +S P + EP+ + L+T+ S Sbjct: 1711 TWRPSQPPTLAPTTMATSRARPTGTASTASK--EPLTTSLAPTLTSELSTSQAETSTPRT 1768 Query: 816 ANNLSMPTSDLPPGASPRKKPR 837 +S T+ + R +P+ Sbjct: 1769 ETTMSPLTNTTTSQGTTRCQPK 1790 >gi|83367077 mucin 16 [Homo sapiens] Length = 14507 Score = 84.0 bits (206), Expect = 7e-16 Identities = 189/839 (22%), Positives = 291/839 (34%), Gaps = 128/839 (15%) Query: 36 GAPSTGLSQAPSQIANSGSA-------------GLINPAATVNDESGRDSEVSAREHMSS 82 G P T S A S A + S L+ ++ VN S +S E ++ Sbjct: 11011 GEPETTPSMATSHGAEASSTVPTVSPEVPGVVTSLVTSSSGVNSTSIPTLILSPGELETT 11070 Query: 83 SSSLQSREEKQEPVVVRPY--PQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGL 140 S S + V P P V + T +S + T P + LS SE Sbjct: 11071 PSMATSHGAEASSAVPTPTVSPGVSGVVTPLVTSSRAVTSTTIP------ILTLSSSE-- 11122 Query: 141 MKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESS-IPQASAIPVATISGQQGHPS 199 P P+M + A + L++ P+VPG VT + SS ++ IP TIS + + Sbjct: 11123 --PETTPSMATSHGVEASSAVLTVSPEVPGMVTSLVTSSRAVTSTTIPTLTISSDEPETT 11180 Query: 200 NLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAA 259 + +S I + A P + +G + V SS T+ S L A+ Sbjct: 11181 TSLVTHSEAKMISAIPTLAVSPTV--------QGLVTSLVTSSGSETSAF---SNLTVAS 11229 Query: 260 TAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPT 319 + + + + P S+ +P TVS + + T + S L R T Sbjct: 11230 SQPETIDSWV-----AHPGTEASSVVP---TLTVSTGEPFTNISLVTHPAESSSTLPRTT 11281 Query: 320 LSIQHP-----PSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTP 374 H PS S + A+S + P P + T + S+G Sbjct: 11282 SRFSHSELDTMPSTVTSPE--AESSSAISTTISPGIPGVLT----------SLVTSSGRD 11329 Query: 375 VAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVV 434 ++A P + + S TA V+H A TST V T P++ SH+ TT +I + Sbjct: 11330 ISA--TFPTVPESPHESEATASWVTH-PAVTSTTVPRTTPNY-SHSEPDTTPSIATSPGA 11385 Query: 435 PQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPP 494 + + PD P +S + SG S + T S P F + T+ Sbjct: 11386 EATSDFPTITVSPDVPDMVTSQVTSSGTDTSIT-IPTLTLSSGEPETTTSFITYSETHTS 11444 Query: 495 SAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASH 554 SA P PVS A + G ST P T Sbjct: 11445 SAIP-----------------TLPVSPGASKMLTSLVISSGTDSTTTF-PTLTETPYEPE 11486 Query: 555 ARHIQGIQPAPISTQGIQPAPIGTPGIQ--------PAPLGTQGIHSATPINTQGLQPAP 606 IQ I PA +T P TP P + + G +++ ++T + P Sbjct: 11487 TTAIQLIHPAETNTM----VPRTTPKFSHSKSDTTLPVAITSPGPEASSAVSTTTISP-- 11540 Query: 607 MGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSAST-------NA 659 + TS V + T P + P T TH ST N Sbjct: 11541 -----DMSDLVTSLVPSSGTDTSTTFPTLSETPYEPETTATWLTHPAETSTTVSGTIPNF 11595 Query: 660 PAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQ 719 +GS PS++ P D + + P V+ + S+ + + A+P Sbjct: 11596 SHRGSDTAPSMV-TSPGVDTRSGVPTTTIPPSIPGVVTSQVTSSATD--TSTAIPTLTPS 11652 Query: 720 PPPTIPTMIAAASPPSQP--AVALSTIPGAVPIT-------PPITTIAAAPPPSVTVGGS 770 P T +A P +Q V + T+P + P T PP T + P T S Sbjct: 11653 PGEPETTASSATHPGTQTGFTVPIRTVPSSEPDTMASWVTHPPQT---STPVSRTTSSFS 11709 Query: 771 LSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPG 829 SS PV + E + P + T+ ++ S A A + ++PT PG Sbjct: 11710 HSSPDATPVMATSPRTEASSAVLTTISPGAPEMVTSQITSSGA--ATSTTVPTLTHSPG 11766 Score = 75.9 bits (185), Expect = 2e-13 Identities = 180/834 (21%), Positives = 305/834 (36%), Gaps = 112/834 (13%) Query: 42 LSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPY 101 +S P+ + GL+ T SG SE SA +++ +SS + E + V P Sbjct: 11192 ISAIPTLAVSPTVQGLVTSLVT---SSG--SETSAFSNLTVASS---QPETIDSWVAHPG 11243 Query: 102 PQVQMLSTHHAVASATP---VAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAP 158 + + V++ P +++ PA + +P + S TMPS +P Sbjct: 11244 TEASSVVPTLTVSTGEPFTNISLVTHPAESSSTLPRTTSR--FSHSELDTMPSTVTSPEA 11301 Query: 159 PST----LSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSII 214 S+ ++ P +PG +T + SS SA + + V + + Sbjct: 11302 ESSSAISTTISPGIPGVLTSLVTSSGRDISATFPTVPESPHESEATASWVTHPAVTSTTV 11361 Query: 215 RSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQ------------ 262 P H P A + ++S T+ + +P+ T+Q Sbjct: 11362 PRTTPNYS-HSEPDTTPSIATSPGAEATSDFPTIT-VSPDVPDMVTSQVTSSGTDTSITI 11419 Query: 263 PAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTA-AHATDSALSRPTLS 321 P + +P + +T S + + T+ + S ++T+ + TDS + PTL+ Sbjct: 11420 PTLTLSSGEPETTTSFITYSETHTSSAIPTLPVSPGASKMLTSLVISSGTDSTTTFPTLT 11479 Query: 322 IQ--HPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAAT 379 P + AI + PA++ + R T PK H+ + T+ Sbjct: 11480 ETPYEPETTAIQLIHPAETNTMVPRTT---------PKFS-HSKSDTTL----------- 11518 Query: 380 VAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQIT 439 P+ T+ P A++A S + S +VT VPS + T++ P P + Sbjct: 11519 --PVAITSPGPEASSAVSTTTISPDMSDLVTSLVPSSGTD----TSTTFPTLSETPYEPE 11572 Query: 440 HTSPRIQPDYPAERSSL----IPISGHRASPNPVAMETRS--DNRPSVPVQFQYFLPTYP 493 T+ + +PAE S+ IP HR S +M T D R VP T P Sbjct: 11573 TTATWLT--HPAETSTTVSGTIPNFSHRGSDTAPSMVTSPGVDTRSGVPTT------TIP 11624 Query: 494 PSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDAS 553 PS + T +S+ T P +P T +S H TV Sbjct: 11625 PSIPGVVTSQVT--SSATDTSTAIPTLTPSPGEPETT-----ASSATHPGTQTGFTVPI- 11676 Query: 554 HARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQG----LQPAPMGT 609 R + +P +++ P TP + + ATP+ A + T Sbjct: 11677 --RTVPSSEPDTMASWVTHPPQTSTPVSRTTSSFSHSSPDATPVMATSPRTEASSAVLTT 11734 Query: 610 QQP-QPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQS-ASTNAPAQGSSPR 667 P PE TS + + AT P P T ++ TH ++ S PA P+ Sbjct: 11735 ISPGAPEMVTSQITSSGAATSTTVPTLTHSPGMPETTALLSTHPRTETSKTFPASTVFPQ 11794 Query: 668 PSILRKKPATDGAKPKSEIHVSMATPVTVSMETV----SNQNNDQPTIAVPPTAQQPP-P 722 S + A+ +P +E ++ T T S+ T+ +++ + PT + +A+ P Sbjct: 11795 VS---ETTASLTIRPGAETSTALPTQTTSSLFTLLVTGTSRVDLSPTASPGVSAKTAPLS 11851 Query: 723 TIP-TMIAAASPPSQPAVALSTIPGAVPIT----PPITTIAAAPPPSVTVGGSLSSVLGP 777 T P T + P S ++ L G + + +T+ P+V+ S S Sbjct: 11852 THPGTETSTMIPTSTLSLGLLETTGLLATSSSAETSTSTLTLTVSPAVSGLSSASITTDK 11911 Query: 778 PVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGAS 831 P E P S PP + TV+ + L + MPT PP S Sbjct: 11912 PQTVTSWNTETSP----SVTSVGPPEFSRTVTGTTMTLIPS-EMPT---PPKTS 11957 Score = 69.3 bits (168), Expect = 2e-11 Identities = 169/799 (21%), Positives = 289/799 (36%), Gaps = 121/799 (15%) Query: 60 PAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPV 119 P+ + E+ S +S L S + +P V S H + A+A+ V Sbjct: 11293 PSTVTSPEAESSSAISTTISPGIPGVLTSLVTSSGRDISATFPTVPE-SPHESEATASWV 11351 Query: 120 AVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPS--TLSLPPKVPGQVTVTME 177 A + P ++S +P P++ + P A A T+++ P VP VT + Sbjct: 11352 THPAVTSTTVPRTTPNYSHS--EPDTTPSIATSPGAEATSDFPTITVSPDVPDMVTSQVT 11409 Query: 178 SSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAA 237 SS S I + T++ G P +T + + S P P+ GAS + + Sbjct: 11410 SSGTDTS-ITIPTLTLSSGEPETTTSFITYSETHT--SSAIPTLPVSPGASKMLTSLVIS 11466 Query: 238 AVMSSSKVTTVLRPTSQLPNAATAQ---PAVQHII---------HQPIQSRPPVTTSNAI 285 + S+ L T P Q PA + + H + PV ++ Sbjct: 11467 SGTDSTTTFPTLTETPYEPETTAIQLIHPAETNTMVPRTTPKFSHSKSDTTLPVAITSPG 11526 Query: 286 PPA--VVATVSATRAQSPVITTTA-AHATDSALSRPTLSIQ--HPPSAAISIQRPAQSRD 340 P A V+T + + S ++T+ + TD++ + PTLS P + A + PA++ Sbjct: 11527 PEASSAVSTTTISPDMSDLVTSLVPSSGTDTSTTFPTLSETPYEPETTATWLTHPAET-S 11585 Query: 341 VTTRITLP--SH------PAL----------GTPKQQLHTMAQKTIFS--TGTPVAAATV 380 T T+P SH P++ G P + + S T + +T Sbjct: 11586 TTVSGTIPNFSHRGSDTAPSMVTSPGVDTRSGVPTTTIPPSIPGVVTSQVTSSATDTSTA 11645 Query: 381 APILATNTIPSATTAGSVSHTQAPTS-TIVTMTVPSH-----SSHATAVTTSNIPVAKVV 434 P L + TTA S +H T T+ TVPS +S T ++ PV++ Sbjct: 11646 IPTLTPSPGEPETTASSATHPGTQTGFTVPIRTVPSSEPDTMASWVTHPPQTSTPVSRTT 11705 Query: 435 PQQITHTSPRIQPDYPA----ERSSLIPISGHRASPNPVAME-TRSDNRPSVPVQFQYFL 489 +H+SP P E SS + + +P V + T S S V Sbjct: 11706 -SSFSHSSPDATPVMATSPRTEASSAVLTTISPGAPEMVTSQITSSGAATSTTVPTLTHS 11764 Query: 490 PTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAIT---AQTGVGVASTVHLNPMQ 546 P P + L+ H T + + +P ++ S A+T + + + Sbjct: 11765 PGMPETTALLSTHPRTETSKTFPASTVFPQVSETTASLTIRPGAETSTALPTQTTSSLFT 11824 Query: 547 LMTVDASHARHIQGIQPAPISTQGI--QPAPIGT-PGIQPAPLGTQGIHSATPINTQGLQ 603 L+ S + +P ++ G+ + AP+ T PG + + + S + T GL Sbjct: 11825 LLVTGTSR------VDLSPTASPGVSAKTAPLSTHPGTETSTMIPTSTLSLGLLETTGLL 11878 Query: 604 PAPMG----------TQQPQPEGKTSAVVLADGATIVA--NPISNP---------FSAAP 642 T P G +SA + D V N ++P FS Sbjct: 11879 ATSSSAETSTSTLTLTVSPAVSGLSSASITTDKPQTVTSWNTETSPSVTSVGPPEFSRTV 11938 Query: 643 AATTVVQTHSQSASTNAPAQGSSPRPSILRKKP-------ATDGAKPK--------SEIH 687 TT+ S+ + + G P+ + + AT G+ P + + Sbjct: 11939 TGTTMTLIPSEMPTPPKTSHGEGVSPTTILRTTMVEATNLATTGSSPTVAKTTTTFNTLA 11998 Query: 688 VSMATPVTV-SMETVSNQN-------NDQPTIAVPP-------TAQQPPPTIPTMIAAAS 732 S+ TP+T M T+++++ N + I+ T P T S Sbjct: 11999 GSLFTPLTTPGMSTLASESVTSRTSYNHRSWISTTSSYNRRYWTPATSTPVTSTFSPGIS 12058 Query: 733 PPSQPAVALSTIPGAVPIT 751 S P+ +T+P VP T Sbjct: 12059 TSSIPSSTAATVPFMVPFT 12077 Score = 67.8 bits (164), Expect = 5e-11 Identities = 191/918 (20%), Positives = 332/918 (36%), Gaps = 126/918 (13%) Query: 6 HPQAGEIEAGGAGGGRR---LQVEMSSQQFPRLG-------APSTGLSQAPSQIANSGSA 55 H + + + GAG R L VE +S +L +P + A S +++ Sbjct: 7364 HSEITTLVSRGAGDVPRPSSLPVEETSPPSSQLSLSAMISPSPVSSTLPASSHSSSASVT 7423 Query: 56 GLINPAATVNDE---SGRDSEVSAREHMSSSSS--LQSREEKQEPVVVRPYPQVQMLSTH 110 L+ P E + + E S+ +SS+S L + E + + P+ + Sbjct: 7424 SLLTPGQVKTTEVLDASAEPETSSPPSLSSTSVEILATSEVTTDTEKIHPFSNTAVTKVG 7483 Query: 111 HAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMP-----SRPIAPAPPSTLSLP 165 + + + P + T A + +M T+ +R I P S+L+ Sbjct: 7484 TSSSGHESPSSVLPDSETTKATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPASSLTTR 7543 Query: 166 PKVPGQVTVTMESSIP-QASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLH 224 + + + + E+S+ +A+ + +G S I + MS + + Sbjct: 7544 LR---ETSTSEETSLATEANTVLSKVSTGATTEVSRTEAISFSRTSMSGPEQSTMSQDIS 7600 Query: 225 IGASHLPRGAAAAAVMSSSKVT---------TVLRPTSQLPNAATAQPAVQHIIHQPIQS 275 IG +PR +A++ + S+K+T + L T L A T H I Sbjct: 7601 IGT--IPRISASSVLTESAKMTITTQTGPSESTLESTLNLNTATTPSWVETHSIVIQGFP 7658 Query: 276 RPPVTTS-----------------NAIPPAVVATVSATRAQSPVITTTAAHATDSALSRP 318 P +TTS PP+ ++ A + PV TT AH S L Sbjct: 7659 HPEMTTSMGRGPGGVSWPSPPFVKETSPPSSPLSLPAVTSPHPVSTTFLAHIPPSPLPVT 7718 Query: 319 TLSIQHPPSAAISIQRPAQ-SRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAA 377 +L P + + + ++ ++ SH L T K HT A +TG Sbjct: 7719 SLLTSGPATTTDILGTSTEPGTSSSSSLSTTSHERLTTYKDTAHTEAVHPSTNTG----- 7773 Query: 378 ATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQ 437 TN +++ S S A +S + T + +S T+ T + + ++ + Sbjct: 7774 -------GTNVATTSSGYKSQSSVLADSSPMCTTSTMGDTSVLTS-TPAFLETRRIQTEL 7825 Query: 438 ITHTSPRIQPDYPAERSSLIPISGHRAS------PNPVAMETRSDNRPSVPVQFQYFLPT 491 + +P ++ +E +S SG + S P E ++ S+P Sbjct: 7826 ASSLTPGLRESSGSEGTS----SGTKMSTVLSKVPTGATTEISKEDVTSIP--------- 7872 Query: 492 YPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVD 551 P+ ++ T S ST SA+ + T+ G T L+ ++ Sbjct: 7873 -GPAQSTISPDISTRTVSWFSTSPVMTESAEITMNTHTSPLGATTQGTSTLDTSSTTSLT 7931 Query: 552 ASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQ 611 +H+ QG + +ST ++ P + P PL + P + PA T Sbjct: 7932 MTHSTISQGFSHSQMSTL-MRRGPEDVSWMSP-PL----LEKTRPSFSLMSSPA---TTS 7982 Query: 612 PQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSIL 671 P P T L + + P+++ ++ A TT + S TN+PA SS IL Sbjct: 7983 PSPVSST----LPESISSSPLPVTSLLTSGLAKTTDMLHKSSEPVTNSPANLSSTSVEIL 8038 Query: 672 RKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAA 731 T + + H S VT + ++ + + T V +Q T P +I Sbjct: 8039 ATSEVTTDTE---KTHPSSNRTVT---DVGTSSSGHESTSFVLADSQTSKVTSPMVI--T 8090 Query: 732 SPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVG-GSLSSVLGPPVPEIKVKEEVEP 790 S +V+ ST PG + I P S+T+G SS G + Sbjct: 8091 STMEDTSVSTST-PGFF----ETSRIQTEPTSSLTLGLRKTSSSEGTSL----------A 8135 Query: 791 MDIMRPVSAVPPLATNTVSPSLALLANNLSM---PTSDLPPGASPRKKPRKQQHVISTEE 847 ++ +S VP AT VS + ++ S+ + P S R I TE Sbjct: 8136 TEMSTVLSGVPTGATAEVSRTEVTSSSRTSISGFAQLTVSPETSTETITRLPTSSIMTES 8195 Query: 848 GDMMETNSTDDEKSTAKS 865 +MM TD ST +S Sbjct: 8196 AEMMIKTQTDPPGSTPES 8213 Score = 65.9 bits (159), Expect = 2e-10 Identities = 155/810 (19%), Positives = 302/810 (37%), Gaps = 129/810 (15%) Query: 135 SFSEGLMKPPPKPTMPSRPIAPAPPSTL-SLPPKVPGQVTVTMESSIPQASAIPVATISG 193 SFS LM P P M S P++ P T+ + P + +T ++ + P T S Sbjct: 6800 SFSSSLM---PSPAMTSPPVSSTLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSPEPTTSS 6856 Query: 194 QQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTS 253 S H I+TT+ + I + P S+S T + TS Sbjct: 6857 PPNLSSTSHEILTTDEDTTAIEAMHP---------------------STSTAATNVETTS 6895 Query: 254 QLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDS 313 + ++ A + ++ P+ T++ + V+T + +++ I + ++ Sbjct: 6896 SGHGSQSSVLADS----EKTKATAPMDTTSTMGHTTVSTSMSVSSETTKIKRESTYSLTP 6951 Query: 314 ALSRPTLSIQHPPSAAISI---------QRPAQSRDVTT--RITLPSHPALGTPKQQLHT 362 L ++S S SI +VT+ R ++P P+ T ++ T Sbjct: 6952 GLRETSISQNASFSTDTSIVLSEVPTGTTAEVSRTEVTSSGRTSIPG-PSQSTVLPEIST 7010 Query: 363 MAQKTIFSTGTPVAAATVAPILATNTIPSATTA-------GSVSHTQAPTSTIVTMTVPS 415 +F++ T +A + + T T PS +T+ S + +QA T + +T P Sbjct: 7011 RTMTRLFASPTMTESAEMT--IPTQTGPSGSTSQDTLTLDTSTTKSQAKTHSTLTQRFP- 7067 Query: 416 HSSHATAVTTSNIPVAKVVPQQITHTS--PRI----QPDYPAERSSLIPISGHRASPNPV 469 HS T ++ ++ + + S P + P SS +P++ S +P+ Sbjct: 7068 HSEMTTLMSRGPGDMSWQSSPSLENPSSLPSLLSLPATTSPPPISSTLPVT---ISSSPL 7124 Query: 470 AMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHT----------------YTPITSSVST 513 + + + P + P S+ P +HT P T++ ++ Sbjct: 7125 PVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDERLTTGKDTTNTEAVHPSTNTAAS 7184 Query: 514 IRQYPVSA-QAPNSAITAQTGVGVASTVHLNPMQ---LMTVDASHARHIQGIQPAPISTQ 569 + P S ++P+SA+ S + + Q + + H IQ IS+ Sbjct: 7185 NVEIPSSGHESPSSALADSETSKATSPMFITSTQEDTTVAISTPHFLETSRIQKESISSL 7244 Query: 570 GIQPAPIGTPGIQPAPLGTQGIHSATPIN----------TQGLQPAPMGTQQPQ--PEGK 617 + G+ + + T + S I T + + G+ + PE Sbjct: 7245 SPKLRETGSSVETSSAIETSAVLSEVSIGATTEISRTEVTSSSRTSISGSAESTMLPEIS 7304 Query: 618 T--------SAVVLADGATIVANPISNPFSAAPAATTVVQT------------------H 651 T ++ +LA+ + + ++P + +T + T H Sbjct: 7305 TTRKIIKFPTSPILAESSEMTIKTQTSPPGSTSESTFTLDTSTTPSLVITHSTMTQRLPH 7364 Query: 652 SQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVS-MATPVTVSMETVSNQNNDQPT 710 S+ + + G PRPS L P + + P S++ +S M +P VS ++ ++ + Sbjct: 7365 SEITTLVSRGAGDVPRPSSL---PVEETSPPSSQLSLSAMISPSPVSSTLPASSHSSSAS 7421 Query: 711 IAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPP----SVT 766 + T Q T + A+A P + +LS+ + T +TT P +VT Sbjct: 7422 VTSLLTPGQ-VKTTEVLDASAEPETSSPPSLSSTSVEILATSEVTTDTEKIHPFSNTAVT 7480 Query: 767 VGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDL 826 G+ SS P + E + M +S + + +T++P+L+ S P S L Sbjct: 7481 KVGTSSSGHESPSSVLPDSETTKATSAMGTISIMGDTSVSTLTPALSNTRKIQSEPASSL 7540 Query: 827 PPGASPRKKPRKQQHVISTEEGDMMETNST 856 R+ ++ ++TE ++ ST Sbjct: 7541 T--TRLRETSTSEETSLATEANTVLSKVST 7568 Score = 65.9 bits (159), Expect = 2e-10 Identities = 199/895 (22%), Positives = 334/895 (37%), Gaps = 110/895 (12%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDE--SGRDSEVSAREHMSSSSSLQSREEKQEP 95 P++ L+ + ++S +TV E SG +EVS E +SS + S ++ Sbjct: 8410 PTSSLTSGLRETSSSERISSATEGSTVLSEVPSGATTEVSRTEVISSRGTSMSGPDQFTI 8469 Query: 96 VVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEG-LMKPPPKPTMPSRPI 154 + LST + + A+T + P + SEG L T S Sbjct: 8470 SPDISTEAITRLSTSPIMTESAESAIT-----IETGSPGATSEGTLTLDTSTTTFWSGTH 8524 Query: 155 APAPPS-----TLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNV 209 + A P +L + PG V S+ +AS++ S P+ MT+ Sbjct: 8525 STASPGFSHSEMTTLMSRTPGDVPWPSLPSVEEASSV-----SSSLSSPA-----MTSTS 8574 Query: 210 QMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRP-----TSQLPNAATAQPA 264 S + P I +S P A + K T +LR TS PN ++ Sbjct: 8575 FFSTL-------PESISSS--PHPVTALLTLGPVKTTDMLRTSSEPETSSPPNLSSTSAE 8625 Query: 265 V---------QHIIHQPIQSRPPVTTSNAI-----PPAVVATVSATRAQSPVITTTAAHA 310 + + IH P + P V I P +V+A + T+ SP+ TT+ Sbjct: 8626 ILATSEVTKDREKIH-PSSNTPVVNVGTVIYKHLSPSSVLADLVTTKPTSPMATTSTLGN 8684 Query: 311 TDSALSRPTL---SIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKT 367 T + S P + P S+ S R + T+ T S G P +++ Sbjct: 8685 TSVSTSTPAFPETMMTQPTSSLTSGLREISTSQETSSATERSASLSGMPTGATTKVSRTE 8744 Query: 368 IFS---TGTP-VAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAV 423 S T TP A +T++P ++T TI +T + + + T T T + S + Sbjct: 8745 ALSLGRTSTPGPAQSTISPEISTETITRISTPLTTTGSAEMTITPKTGHSGASSQGTFTL 8804 Query: 424 TTSNIPVAKVVPQQITHTSPRIQPDYPAER-----SSLIPISGHRASPNPVAMETRSDNR 478 TS+ TH SP P R S S + SP + + Sbjct: 8805 DTSSRASWPGTHSAATHRSPHSGMTTPMSRGPEDVSWPSRPSVEKTSPPSSLVSLSAVTS 8864 Query: 479 PSVPVQFQYFLPTYPPSAYPL-AAHTYTPI---TSSVSTIRQYPVSAQAPNSAITAQTGV 534 PS P+ Y P+ + PL +TP+ T+ + PV+ P+ IT+ + Sbjct: 8865 PS-PL---YSTPSESSHSSPLRVTSLFTPVMMKTTDMLDTSLEPVTTSPPSMNITSDESL 8920 Query: 535 GVA-STVHLNPMQLMTVDA-SHARHIQGIQPAPISTQGI-QPAPIGTPGIQPAPLGTQGI 591 + +T+ +QL A + I Q S G+ +P+ + +P + + + + Sbjct: 8921 ATSKATMETEAIQLSENTAVTQMGTISARQEFYSSYPGLPEPSKVTSPVVTSSTI-KDIV 8979 Query: 592 HSATPINTQ--GLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQ 649 + P +++ ++ T P P +TS AT P + P+ A +A T+ Sbjct: 8980 STTIPASSEITRIEMESTSTLTPTPR-ETSTSQEIHSAT---KPSTVPYKALTSA-TIED 9034 Query: 650 THSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHV-SMATPVTVSMETVSNQNNDQ 708 + +Q S+ ++G SP S + + +T+ S + + +T +T++ +T S + Sbjct: 9035 SMTQVMSS---SRGPSPDQSTMSQDISTEVITRLSTSPIKTESTEMTITTQTGSPGATSR 9091 Query: 709 PTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVG 768 T+ + + T T S SQ +S PG VP PSV Sbjct: 9092 GTLTLDTSTTFMSGTHSTASQGFS-HSQMTALMSRTPGDVP---------WLSHPSVEEA 9141 Query: 769 GSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVS-PSLALLANNLSMPTSDLP 827 S S L PV M PVS+ P + ++ S P +LL + L T L Sbjct: 9142 SSASFSLSSPV-----------MTSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELLG 9190 Query: 828 PGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLVKAEKRKSPPKEYID 882 + P S E + E +TD EK +++ +SP D Sbjct: 9191 TSSEPETSSPPNLSSTSAEILAITEV-TTDTEKLEMTNVVTSGYTHESPSSVLAD 9244 Score = 62.0 bits (149), Expect = 3e-09 Identities = 178/881 (20%), Positives = 312/881 (35%), Gaps = 171/881 (19%) Query: 95 PVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLS--FSEGLMKPPPKPTMPSR 152 P++ + P ++S+ A S +PV+ T P + + +P++ + GL K S Sbjct: 7963 PLLEKTRPSFSLMSSP-ATTSPSPVSSTLPESISSSPLPVTSLLTSGLAKTTDMLHKSSE 8021 Query: 153 PI--APAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLH-------- 202 P+ +PA S+ S+ +VT E + P ++ + GH S Sbjct: 8022 PVTNSPANLSSTSVEILATSEVTTDTEKTHPSSNRTVTDVGTSSSGHESTSFVLADSQTS 8081 Query: 203 -----HIMTTNVQMSIIRSNAPG---------PPLHIGASHLPRGAAAAAVMSSSKVTTV 248 ++T+ ++ + + ++ PG P L + +++ +++++TV Sbjct: 8082 KVTSPMVITSTMEDTSVSTSTPGFFETSRIQTEPTSSLTLGLRKTSSSEGTSLATEMSTV 8141 Query: 249 LRPTSQLPNAATAQ-----------PAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSA-- 295 L S +P ATA+ ++ + T +P + + T SA Sbjct: 8142 L---SGVPTGATAEVSRTEVTSSSRTSISGFAQLTVSPETSTETITRLPTSSIMTESAEM 8198 Query: 296 ---TRAQSPVITTTAAHATDSAL--------SRPTLSIQHPPSAAISIQRPAQS------ 338 T+ P T + H D + S T H + + P Sbjct: 8199 MIKTQTDPPGSTPESTHTVDISTTPNWVETHSTVTQRFSHSEMTTLVSRSPGDMLWPSQS 8258 Query: 339 --RDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNT-------- 388 + ++ +L S PA +P T+ + F + + + + P L T Sbjct: 8259 SVEETSSASSLLSLPATTSPSPVSSTLVED--FPSASLPVTSLLNPGLVITTDRMGISRE 8316 Query: 389 --IPSATTAGSVSHT--------------QAPTSTIVT---MTVPSHSSHATAVTTSNIP 429 S + S SH Q T T VT ++ H S ++ ++ S P Sbjct: 8317 PGTSSTSNLSSTSHERLTTLEDTVDTEDMQPSTHTAVTNVRTSISGHESQSSVLSDSETP 8376 Query: 430 VAKVVPQQITHT------SPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPV 483 A P T+T S + R + P S + ET S R S Sbjct: 8377 KA-TSPMGTTYTMGETSVSISTSDFFETSRIQIEPTSSLTSG----LRETSSSERISSAT 8431 Query: 484 QFQYFLPTYPPSAYPLAAHT-----------------YTP--ITSSVSTIRQYPVSAQAP 524 + L P A + T +P T +++ + P+ ++ Sbjct: 8432 EGSTVLSEVPSGATTEVSRTEVISSRGTSMSGPDQFTISPDISTEAITRLSTSPIMTESA 8491 Query: 525 NSAITAQTGVGVAS---TVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGI 581 SAIT +TG A+ T+ L+ +H+ G + ++T + TPG Sbjct: 8492 ESAITIETGSPGATSEGTLTLDTSTTTFWSGTHSTASPGFSHSEMTTLMSR-----TPGD 8546 Query: 582 QPAPLGTQGIHSATPINTQGLQPAPMGTQ--QPQPEGKTSAVVLADGATIVANPISNPFS 639 P P + A+ +++ PA T PE +S+ +P++ + Sbjct: 8547 VPWP-SLPSVEEASSVSSSLSSPAMTSTSFFSTLPESISSS----------PHPVTALLT 8595 Query: 640 AAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSME 699 P TT + S T++P SS IL T K + +IH S TPV V++ Sbjct: 8596 LGPVKTTDMLRTSSEPETSSPPNLSSTSAEILATSEVT---KDREKIHPSSNTPV-VNVG 8651 Query: 700 TVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAA 759 TV ++ ++ + PT P +A S +V+ ST P P T+ Sbjct: 8652 TVIYKHLSPSSVLADLVTTK--PTSP--MATTSTLGNTSVSTST-----PAFP--ETMMT 8700 Query: 760 APPPSVTVGGSLSSVLGPPVPEIKVKEEV-EPMDIMRPVSAVPPLATNTVSPSLALLANN 818 P S+T G + EI +E + +S +P AT VS + AL Sbjct: 8701 QPTSSLTSG----------LREISTSQETSSATERSASLSGMPTGATTKVSRTEALSLGR 8750 Query: 819 LSMP---TSDLPPGASPRKKPRKQQHVISTEEGDMMETNST 856 S P S + P S R + +T +M T T Sbjct: 8751 TSTPGPAQSTISPEISTETITRISTPLTTTGSAEMTITPKT 8791 Score = 60.8 bits (146), Expect = 6e-09 Identities = 182/866 (21%), Positives = 306/866 (35%), Gaps = 173/866 (19%) Query: 52 SGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQ------SREEKQEPVVVRPYPQVQ 105 S S L++ A+ + D+ S S H ++SS+ S + K V+ Sbjct: 721 STSIPLLSSASVLEDKVSATSTFS---HHKATSSITTGTPEISTKTKPSSAVLSSMTLSN 777 Query: 106 MLSTHHAVASAT-PVAVTAPPAHLTPAVPLSFS---EGLMKPPPKPTMPSRPIAPAPPST 161 ++ V +AT P+ +P T L+ S E P PT + PST Sbjct: 778 AATSPERVRNATSPLTHPSPSGEETAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPST 837 Query: 162 LSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPS-NLHHIMTTNVQMSIIRSNAPG 220 LSLP V G V T SS P + + +PS + + V+ ++ ++ P Sbjct: 838 LSLP-SVSG-VKTTFSSSTPSTHLFTSGEETEETSNPSVSQPETSVSRVRTTLASTSVPT 895 Query: 221 PPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLP---NAATAQPAVQHIIHQPIQSRP 277 P + +A SSS + + LR TS + +A P + H+ S+ Sbjct: 896 PVFPT----MDTWPTRSAQFSSSHLVSELRATSSTSVTNSTGSALPKISHLTGTATMSQT 951 Query: 278 PVTTSN--AIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRP 335 T N A P + ++ R ++ + + T +T + T+ + S P Sbjct: 952 NRDTFNDSAAPQSTTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTS-------P 1004 Query: 336 AQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAP-ILATNTIPSATT 394 A S T I PS L T + + + ST P+ + L T+ +P TT Sbjct: 1005 ATSSMEATSIREPSTTILTT--ETTNGPGSMAVASTNIPIGKGYITEGRLDTSHLPIGTT 1062 Query: 395 AGS---VSHTQAPTSTIVTMTVPSHSSHATAVTTSN----------------------IP 429 A S + T A S ++++ PS S A +T IP Sbjct: 1063 ASSETSMDFTMAKESVSMSVS-PSQSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITIP 1121 Query: 430 ---VAKVVPQQITHTSPRIQPDYPAERSSLIPI-SGHRASPNPVA--------------- 470 + + Q+T T P PD + RS+ + I S +SP P Sbjct: 1122 RDGTSSALTPQMTATHPP-SPDPGSARSTWLGILSSSPSSPTPKVTMSSTFSTQRVTTSM 1180 Query: 471 ----METRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITS------------SVSTI 514 +ET N P++P P+ P++ + T P+ + + T+ Sbjct: 1181 IMDTVETSRWNMPNLPSTTS-LTPSNIPTSGAIGKSTLVPLDTPSPATSLEASEGGLPTL 1239 Query: 515 RQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPA 574 YP S P+ + A ST+ L + ++P + Sbjct: 1240 STYPESTNTPSIHLGAHASSESPSTIKLTMASV-------------VKPGSYT------- 1279 Query: 575 PIGTPGIQPAPLGTQGIHSATP--INTQGLQP---APMGTQQPQPEGKTSAVVLADGATI 629 P+ P I+ IH +T + G P AP T T+ + D Sbjct: 1280 PLTFPSIE------THIHVSTARMAYSSGSSPEMTAPGETNTGSTWDPTTYITTTDPKDT 1333 Query: 630 VANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPS--------ILRKKPATDGAK 681 + +S P S TT + H ++ S A SP+ S + TD + Sbjct: 1334 SSAQVSTPHSVRTLRTT--ENHPKTESATPAAYSGSPKISSSPNLTSPATKAWTITDTTE 1391 Query: 682 PKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTI--PTMIAAASPPSQPAV 739 +++H + + ET Q+ P V PT+ PTI T+ + P +P V Sbjct: 1392 HSTQLHYTKLAEKSSGFET---QSAPGPVSVVIPTS----PTIGSSTLELTSDVPGEPLV 1444 Query: 740 ALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSA 799 AP T+ +++ L + E + +DI P S Sbjct: 1445 -------------------LAPSEQTTITLPMATWLSTSLTEEMASTD---LDISSPSS- 1481 Query: 800 VPPLATNTVSPSLALLANNLSMPTSD 825 P++T + P ++ ++ LS +D Sbjct: 1482 --PMSTFAIFPPMSTPSHELSKSEAD 1505 Score = 59.7 bits (143), Expect = 1e-08 Identities = 186/873 (21%), Positives = 306/873 (35%), Gaps = 182/873 (20%) Query: 33 PRLGAPSTGLS-QAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREE 91 P PST S P+ A + P + D G + S +S+LQ Sbjct: 4556 PVSSEPSTATSPMVPASSMGDALASISIPGSETTDIEGEPTS-SLTAGRKENSTLQEMNS 4614 Query: 92 KQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPS 151 E ++ V A+ AT + V + A P S K P ++ S Sbjct: 4615 TTESNIILSNVSVG------AITEATKMEVPSFDATFIPTPAQS-----TKFPDIFSVAS 4663 Query: 152 RPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVA----TISGQQGHPSNL-----H 202 ++ +PP T+S +T T S S IP+A T+ G PS + H Sbjct: 4664 SRLSNSPPMTIST------HMTTTQTGSSGATSKIPLALDTSTLETSAGTPSVVTEGFAH 4717 Query: 203 HIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQ 262 +TT + + + PP AS P+SQ P T Sbjct: 4718 SKITTAMNNDVKDVSQTNPPFQDEASS---------------------PSSQAPVLVTTL 4756 Query: 263 PAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSI 322 P+ Q + PV+ S+ + ++V T A D++L T S Sbjct: 4757 PSSVAFTPQWHSTSSPVSMSSVLTSSLVKT---------------AGKVDTSLETVTSS- 4800 Query: 323 QHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAP 382 P S + ++ + + TT I +HP++ T + + GT +A Sbjct: 4801 --PQSMSNTLDDISVTSAATTDIE-TTHPSINT-----------VVTNVGTTGSAFESHS 4846 Query: 383 ILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA---TAVTTSNIPVAK--VVPQQ 437 ++ PS T+ +V+ T T ++ ++P S T T+S P + + Q+ Sbjct: 4847 TVSAYPEPSKVTSPNVT-TSTMEDTTISRSIPKSSKTTRTETETTSSLTPKLRETSISQE 4905 Query: 438 ITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAY 497 IT ++ +S +P + V +R+D S F P + Sbjct: 4906 ITSST----------ETSTVPYKELTGATTEV---SRTDVTSSSSTSFPG--PDQSTVSL 4950 Query: 498 PLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARH 557 ++ T T +++S P+ ++ IT QTG A++ T+D S+ Sbjct: 4951 DISTETNTRLSTS-------PIMTESAEITITTQTGPHGATS-----QDTFTMDPSNT-- 4996 Query: 558 IQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGK 617 TP GIHSA L + ++ PQ Sbjct: 4997 --------------------TP--------QAGIHSAMTHGFSQLDVTTLMSRIPQDVSW 5028 Query: 618 TSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPAT 677 TS ++ + F ++PA T T S +ST + SSP S+L T Sbjct: 5029 TSP------PSVDKTSSPSSFLSSPAMT----TPSLISSTLPEDKLSSPMTSLL-----T 5073 Query: 678 DGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIA-------- 729 G ++I + PVT S+ S+ ++ +A ++ P++ Sbjct: 5074 SGLVKITDILRTRLEPVTSSLPNFSSTSD--KILATSKDSKDTKEIFPSINTEETNVKAN 5131 Query: 730 -AASPPSQPAVALSTIPGAVPITPPITTIA-AAPPPSVTVGGSLSSV---------LGPP 778 + PA+A S P A TT+ AP S+ V GS + L P Sbjct: 5132 NSGHESHSPALADSETPKATTQMVITTTVGDPAPSTSMPVHGSSETTNIKREPTYFLTPR 5191 Query: 779 VPEIKVKEEVE-PMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSD---LPPGASPRK 834 + E +E P D +S VP VS + ++ +S P D +PP + Sbjct: 5192 LRETSTSQESSFPTDTSFLLSKVPTGTITEVSSTGVNSSSKISTPDHDKSTVPPDTFTGE 5251 Query: 835 KPRKQQHVISTEEGDMMETNSTDDEKSTAKSLL 867 PR I T+ +M T +S + S L Sbjct: 5252 IPRVFTSSIKTKSAEMTITTQASPPESASHSTL 5284 Score = 58.9 bits (141), Expect = 2e-08 Identities = 146/747 (19%), Positives = 255/747 (34%), Gaps = 104/747 (13%) Query: 128 LTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIP 187 L + P+ FS T+P+ + +T G + T E + S + Sbjct: 10324 LPSSTPVPFSSSTFTTTDSSTIPALHEITSSSATPYRVDTSLGTESSTTEGRLVMVSTLD 10383 Query: 188 VATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTT 247 ++ G+ L MT +V++ + S P L ++ L R Sbjct: 10384 TSSQPGRTSSSPILDTRMTESVELGTVTSAYQVPSL---STRLTR------------TDG 10428 Query: 248 VLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTA 307 ++ +++PN A + ++ + + P T+++ P + T R ++ TTTA Sbjct: 10429 IMEHITKIPNEAAHRGTIRPV-------KGPQTSTSPASPKGLHTGGTKRMET---TTTA 10478 Query: 308 AHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSH---PALGTPKQQLHTMA 364 T +AL T+R TL + P LGT +M Sbjct: 10479 LKTTTTALK------------------------TTSRATLTTSVYTPTLGTLTPLNASMQ 10514 Query: 365 QKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVT 424 + T + V P + T AT+ G+ + T P +T S ++ A+ V+ Sbjct: 10515 MASTIPTEMMITTPYVFPDVPETTSSLATSLGAETSTALPRTTPSVFNRESETT-ASLVS 10573 Query: 425 TSNIPVAKVVPQ-QITHTSPRIQPDYPAERSSLIPISGHRASPN--PVAMETRSDNRPSV 481 S + V+ ++ + P + + IP + +PN ++T S S Sbjct: 10574 RSGAERSPVIQTLDVSSSEPDTTASWVIHPAETIPTVS-KTTPNFFHSELDTVSSTATSH 10632 Query: 482 PVQFQYFLPTYPPSAYPLAAHTYTPIT--SSVSTIRQYPVSAQAPNSAITAQTGVG-VAS 538 +PT + P TP+ S T +P ++P+ T T + A Sbjct: 10633 GADVSSAIPT---NISPSELDALTPLVTISGTDTSTTFPTLTKSPHETETRTTWLTHPAE 10689 Query: 539 TVHLNPMQLMTVDASHARHIQGIQPAP-ISTQGIQPAPIGTPGI------QPAPLGTQGI 591 T P + + I +P T P +PG Q GT Sbjct: 10690 TSSTIPRTIPNFSHHESDATPSIATSPGAETSSAIPIMTVSPGAEDLVTSQVTSSGTDRN 10749 Query: 592 HSATPINTQGLQPAPMGTQQPQPEGKTSAVVLAD------------------GATIVANP 633 + + +P + + PE +TS+ + T N Sbjct: 10750 MTIPTLTLSPGEPKTIASLVTHPEAQTSSAIPTSTISPAVSRLVTSMVTSLAAKTSTTNR 10809 Query: 634 ISNPFSAAPAATTVVQTHSQSASTNAPAQGS---SPRPSILRKKPATDGAKPKSEIH--- 687 PA T + TH S P S + + GA+ S + Sbjct: 10810 ALTNSPGEPATTVSLVTHPAQTSPTVPWTTSIFFHSKSDTTPSMTTSHGAESSSAVPTPT 10869 Query: 688 VSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGA 747 VS P V+ S++ TI + + P T P+M + + A+ T+ Sbjct: 10870 VSTEVPGVVTPLVTSSRAVISTTIPILTLSPGEPETTPSMATSHGEEASSAIPTPTVSPG 10929 Query: 748 VP--ITPPITTIAAAPPPSVTVGGSLSSVLGPP--VPEIKVKEEVEPMDIMRPV-SAVPP 802 VP +T +T+ A ++ + L+ LG P P + E + V VP Sbjct: 10930 VPGVVTSLVTSSRAVTSTTIPI---LTFSLGEPETTPSMATSHGTEAGSAVPTVLPEVPG 10986 Query: 803 LATNTVSPSLALLANNLSMPTSDLPPG 829 + T+ V+ S A+ + L PT L PG Sbjct: 10987 MVTSLVASSRAVTSTTL--PTLTLSPG 11011 Score = 58.2 bits (139), Expect = 4e-08 Identities = 187/864 (21%), Positives = 301/864 (34%), Gaps = 121/864 (14%) Query: 27 MSSQQFPRLGAPSTG-----LSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMS 81 +S+ P STG LS+A + A +G I SG S S E Sbjct: 10262 LSTDLLPSAETISTGTVMPSLSEAMTSFATTGVPRAI---------SGSGSPFSRTESGP 10312 Query: 82 SSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTP-AVPLSFSEGL 140 ++L + E P+ +T +S P + TP V S Sbjct: 10313 GDATLSTIAESLPSSTPVPFSSSTFTTTD---SSTIPALHEITSSSATPYRVDTSLGTES 10369 Query: 141 MKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTME-SSIPQASAIP-----VATISGQ 194 + M S + P S P + ++T ++E ++ A +P + G Sbjct: 10370 STTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGTVTSAYQVPSLSTRLTRTDGI 10429 Query: 195 QGH----PSNLHHIMTTNVQMSIIRSNAPGPP--LHIGASHLPRGAAAAAVMSSSKVTTV 248 H P+ H T S +P P LH G + A +++ + T Sbjct: 10430 MEHITKIPNEAAHRGTIRPVKGPQTSTSPASPKGLHTGGTKRMETTTTALKTTTTALKTT 10489 Query: 249 LRPTSQL----PNAATAQPAVQHI-IHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVI 303 R T P T P + + I + +TT P T S + Sbjct: 10490 SRATLTTSVYTPTLGTLTPLNASMQMASTIPTEMMITTPYVFPDVPETTSSLATSLGAET 10549 Query: 304 TTTAAHATDSALSRPTLSIQHPPSAAISIQRPA-QSRDVT-----TRITLPSHPALGTPK 357 +T T S +R + + S + + + P Q+ DV+ T + HPA P Sbjct: 10550 STALPRTTPSVFNRESETTASLVSRSGAERSPVIQTLDVSSSEPDTTASWVIHPAETIPT 10609 Query: 358 QQLHT-----MAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMT 412 T T+ ST T A V+ + TN PS A + T + T T T Sbjct: 10610 VSKTTPNFFHSELDTVSSTATS-HGADVSSAIPTNISPSELDALTPLVTISGTDTSTTFP 10668 Query: 413 VPSHSSHAT----------AVTTSNIPVAKVVPQQITHTS---PRIQPDYPAERSSLIPI 459 + S H T A T+S IP + +P H S P I AE SS IPI Sbjct: 10669 TLTKSPHETETRTTWLTHPAETSSTIP--RTIPNFSHHESDATPSIATSPGAETSSAIPI 10726 Query: 460 SGHRASPNP----VAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIR 515 SP + T S ++ + P P + L H +S++ T Sbjct: 10727 M--TVSPGAEDLVTSQVTSSGTDRNMTIPTLTLSPGEPKTIASLVTHPEAQTSSAIPTST 10784 Query: 516 QYPVSAQAPNSAITAQTGVGVASTVHL--NPMQLMTVDASHARHIQGIQPAPISTQGIQP 573 P ++ S +T+ + L +P + T + Q P +T Sbjct: 10785 ISPAVSRLVTSMVTSLAAKTSTTNRALTNSPGEPATTVSLVTHPAQTSPTVPWTTSIFFH 10844 Query: 574 APIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVAN- 632 + T P+ + G S++ + P T + G + +V + A I Sbjct: 10845 SKSDTT---PSMTTSHGAESSSAV--------PTPTVSTEVPGVVTPLVTSSRAVISTTI 10893 Query: 633 PISNPFSAAPAATTVVQT-HSQSASTNAPAQGSSPR-PSILRKKPATDGAKPKSEIHV-- 688 PI P T + T H + AS+ P SP P ++ + A + I + Sbjct: 10894 PILTLSPGEPETTPSMATSHGEEASSAIPTPTVSPGVPGVVTSLVTSSRAVTSTTIPILT 10953 Query: 689 -SMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGA 747 S+ P T +++ + + AVP + P + +++A S AV +T+P Sbjct: 10954 FSLGEPETTP--SMATSHGTEAGSAVPTVLPEVPGMVTSLVA-----SSRAVTSTTLP-T 11005 Query: 748 VPITP--PITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT 805 + ++P P TT P + + G SS + PE VP + T Sbjct: 11006 LTLSPGEPETT----PSMATSHGAEASSTVPTVSPE------------------VPGVVT 11043 Query: 806 NTVSPSLALLANNLSMPTSDLPPG 829 + V+ S + N+ S+PT L PG Sbjct: 11044 SLVTSSSGV--NSTSIPTLILSPG 11065 Score = 55.8 bits (133), Expect = 2e-07 Identities = 161/738 (21%), Positives = 255/738 (34%), Gaps = 142/738 (19%) Query: 78 EHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFS 137 E SSSSSL P + + S H+ +S PV +V LS + Sbjct: 4154 EETSSSSSLVPIHATTSP------SNILLTSQGHSPSSTPPVT----------SVFLSET 4197 Query: 138 EGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGH 197 GL K + P PP+ S G+ T E+S + Sbjct: 4198 SGLGKTTDMSRISLEPGTSLPPNLSS----TAGEALSTYEASRDTKA------------- 4240 Query: 198 PSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPN 257 +HH T V S+ P H A + +++S + + TS + Sbjct: 4241 ---IHHSADTAVTNMEATSSEYSPI----PGHTKPSKATSPLVTSHIMGDITSSTSVFGS 4293 Query: 258 AATAQPAVQHIIHQPIQSRPP--VTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSAL 315 + T + ++Q +Q R V +S V+ VS+ A + V T A ++ +++ Sbjct: 4294 SETTEIETVSSVNQGLQERSTSQVASSATETSTVITHVSSGDATTHVTKTQATFSSGTSI 4353 Query: 316 SRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPV 375 S P I + T T PS + T + TI + P Sbjct: 4354 SSPHQFI-------------TSTNTFTDVSTNPSTSLIMTESSGV------TITTQTGPT 4394 Query: 376 AAATVAP-ILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVV 434 AAT P +L T+T+P T T + +T S T + + Sbjct: 4395 GAATQGPYLLDTSTMPYLT------------ETPLAVTPDFMQSEKTTLISKG------- 4435 Query: 435 PQQITHTSPR--IQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTY 492 P+ ++ TSP + YP SSL P + P A T S PV L + Sbjct: 4436 PKDVSWTSPPSVAETSYP---SSLTPFL---VTTIPPATSTLQGQHTSSPVSATSVLTSG 4489 Query: 493 PPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAIT-----------AQTGVGVASTVH 541 + + P+T+S + A +A T A T +G AS+ H Sbjct: 4490 LVKTTDMLNTSMEPVTNSPQNLNNPSNEILATLAATTDIETIHPSINKAVTNMGTASSAH 4549 Query: 542 LNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQG 601 + T+ S P S+ G A I PG + + + S T + Sbjct: 4550 VLHS---TLPVSSEPSTATSPMVPASSMGDALASISIPGSETTDIEGEPTSSLTAGRKEN 4606 Query: 602 LQPAPMGTQQPQPEGKTSAVVLAD---GATIVANPISNP-----FSAAPAATTV---VQT 650 T Q S ++L++ GA A + P F PA +T + + Sbjct: 4607 ------STLQEMNSTTESNIILSNVSVGAITEATKMEVPSFDATFIPTPAQSTKFPDIFS 4660 Query: 651 HSQSASTNAPAQGSSPRPSILRKKPATDGAKPK-------SEIHVSMATPVTVS-----M 698 + S +N+P S + + + GA K S + S TP V+ Sbjct: 4661 VASSRLSNSPPMTISTH--MTTTQTGSSGATSKIPLALDTSTLETSAGTPSVVTEGFAHS 4718 Query: 699 ETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIA 758 + + NND V +Q PP A+SP SQ V ++T+P +V TP + + Sbjct: 4719 KITTAMNND-----VKDVSQTNPPF---QDEASSPSSQAPVLVTTLPSSVAFTPQWHSTS 4770 Query: 759 AAPPPSVTVGGSLSSVLG 776 + S + SL G Sbjct: 4771 SPVSMSSVLTSSLVKTAG 4788 Score = 55.5 bits (132), Expect = 3e-07 Identities = 176/782 (22%), Positives = 295/782 (37%), Gaps = 168/782 (21%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVV 97 PST LS+A S SG +G+ NP++T E S++ S +++ P Sbjct: 2065 PSTSLSEALS----SGHSGVSNPSSTTT------------EFPLFSAASTSAAKQRNPET 2108 Query: 98 VRPYPQVQMLSTHHAVASA-TPVAVTAPPAHLTPAVPLSFS-------EGL-MKPPPKPT 148 PQ ST + AS+ T ++ T A ++ VPL + GL + P+ Sbjct: 2109 ETHGPQNTAASTLNTDASSVTGLSETPVGASISSEVPLPMAITSRSDVSGLTSESTANPS 2168 Query: 149 MPSRPIAPAP-PSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTT 207 + + A T+SLP V+ M P +IP+ + HP TT Sbjct: 2169 LGTASSAGTKLTRTISLPTS-ESLVSFRMNKD-PWTVSIPLGS------HP-------TT 2213 Query: 208 NVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQH 267 N + S I N+ GPP ++TV P+ Sbjct: 2214 NTETS-IPVNSAGPP---------------------GLSTVASDVIDTPSDGA------- 2244 Query: 268 IIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPS 327 +S P V+ S + P V T+S ++ T + T SR T S Sbjct: 2245 ------ESIPTVSFSPS-PDTEVTTISHFPEKTTHSFRTISSLTHELTSRVTPIPGDWMS 2297 Query: 328 AAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATN 387 +A+S + S +T LG ++TI S AA T +PI+ T Sbjct: 2298 SAMSTKPTGASPSIT----------LG---------ERRTITS-----AAPTTSPIVLTA 2333 Query: 388 TIPSATTAGSVSHTQAPTSTIV----TMTVPSHSSHA-----TAVTTSNIPVAK---VVP 435 + +T + T TS I+ T +PS SS + T++ +S + V K + P Sbjct: 2334 SFTETSTVSLDNETTVKTSDILDARKTNELPSDSSSSSDLINTSIASSTMDVTKTASISP 2393 Query: 436 QQIT----HTSPRI----QPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQY 487 I+ +SP + +P P + + S N +++ S N P Sbjct: 2394 TSISGMTASSSPSLFSSDRPQVPTSTTETNTATSPSVSSNTYSLDGGS-NVGGTPSTLPP 2452 Query: 488 FLPTYPPS------AYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQ-TGVGVASTV 540 F T+P A+ T++ + S+ + + P S+ + +++ A T V ST Sbjct: 2453 FTITHPVETSSALLAWSRPVRTFSTMVSTDTASGENPTSSNSVVTSVPAPGTWTSVGSTT 2512 Query: 541 HLNPMQLMTVD---ASHARHIQGIQPAPISTQGIQPAPI-GTPGIQPAPLGT----QGIH 592 L M + +H+ I+PA T + A + G+ A L T + IH Sbjct: 2513 DLPAMGFLKTSPAGEAHSLLASTIEPATAFTPHLSAAVVTGSSATSEASLLTTSESKAIH 2572 Query: 593 SA-----TPIN-----TQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAP 642 S+ TP + T + + + TS +++ D TI+ + +S P S P Sbjct: 2573 SSPQTPTTPTSGANWETSATPESLLVVTETSDTTLTSKILVTD--TILFSTVSTPPSKFP 2630 Query: 643 AATTVVQTHSQSASTNAPA---QGSSPRPSILRKKPATD---------GAKPKSEIHVS- 689 + T+ + + PA + P S+ +T G P++ + +S Sbjct: 2631 STGTLSGASFPTLLPDTPAIPLTATEPTSSLATSFDSTPLVTIASDSLGTVPETTLTMSE 2690 Query: 690 MATPVTVSMETVSNQNNDQPTIAVPPTAQ---QPPPTIPTMIAA---ASPPSQPAVALST 743 + + ++TVSN + P I + + P T P+ I A + VALST Sbjct: 2691 TSNGDALVLKTVSNPDRSIPGITIQGVTESPLHPSSTSPSKIVAPRNTTYEGSITVALST 2750 Query: 744 IP 745 +P Sbjct: 2751 LP 2752 Score = 52.8 bits (125), Expect = 2e-06 Identities = 176/834 (21%), Positives = 282/834 (33%), Gaps = 152/834 (18%) Query: 78 EHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLS-- 135 E SSSSSL S P V PQ S+ + TP V P LS Sbjct: 10016 EKTSSSSSLLSLPVTTSPSVSSTLPQSIPSSSFSVTSLLTPGMVKTTDTSTEPGTSLSPN 10075 Query: 136 --------FSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESS---IPQAS 184 + + + PS +A T S ++ V++ E S P + Sbjct: 10076 LSGTSVEILAASEVTTDTEKIHPSSSMAVTNVGTTSSGHELYSSVSIHSEPSKATYPVGT 10135 Query: 185 AIPVATISGQQGHPSNLH----------HIMT----TNVQM---SIIRSNAPGPPLHIGA 227 +A S P+N H+ + TN+ + S+ +N P P G+ Sbjct: 10136 PSSMAETSISTSMPANFETTGFEAEPFSHLTSGFRKTNMSLDTSSVTPTNTPSSP---GS 10192 Query: 228 SHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIP- 286 +HL + + S+ + P SQ + I P + P +T S I Sbjct: 10193 THLLQSSKTDFTSSAKTSSPDWPPASQYTE-------IPVDIITPFNASPSITESTGITS 10245 Query: 287 -PAVVATVSATRAQSPVIT--TTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTT 343 P T+S T + + T +A + P+LS A S R ++ Sbjct: 10246 FPESRFTMSVTESTHHLSTDLLPSAETISTGTVMPSLS-----EAMTSFATTGVPRAISG 10300 Query: 344 RITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAAT-------VAPILATNTIPSA---- 392 + S G L T+A+ ST P +++T P L T SA Sbjct: 10301 SGSPFSRTESGPGDATLSTIAESLPSSTPVPFSSSTFTTTDSSTIPALHEITSSSATPYR 10360 Query: 393 --TTAGSVSHTQ----APTSTIVTMTVPSHSSHATAVTT--------SNIPVAKVVPQ-- 436 T+ G+ S T ST+ T + P +S + + T + A VP Sbjct: 10361 VDTSLGTESSTTEGRLVMVSTLDTSSQPGRTSSSPILDTRMTESVELGTVTSAYQVPSLS 10420 Query: 437 -QITHTSPRIQ-----PDYPAERSSLIPISGHRASPNPVA-----------METRSDNRP 479 ++T T ++ P+ A R ++ P+ G + S +P + MET + Sbjct: 10421 TRLTRTDGIMEHITKIPNEAAHRGTIRPVKGPQTSTSPASPKGLHTGGTKRMETTTTALK 10480 Query: 480 SVPVQFQ-YFLPTYPPSAYPLAAHTYTPITSSVSTIRQYP---------VSAQAPNSAIT 529 + + T S Y T TP+ +S+ P V P + + Sbjct: 10481 TTTTALKTTSRATLTTSVYTPTLGTLTPLNASMQMASTIPTEMMITTPYVFPDVPETTSS 10540 Query: 530 AQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPI----GTPGIQPAP 585 T +G ++ L P +V + + +S G + +P+ +P Sbjct: 10541 LATSLGAETSTAL-PRTTPSVFNRESETTASL----VSRSGAERSPVIQTLDVSSSEPDT 10595 Query: 586 LGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAAT 645 + IH A I T + T+ AD ++ + IS S A T Sbjct: 10596 TASWVIHPAETIPTVSKTTPNFFHSELDTVSSTATSHGADVSSAIPTNISP--SELDALT 10653 Query: 646 TVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEI---------HVSMATP--- 693 +V ST P SP + R T A+ S I H S ATP Sbjct: 10654 PLVTISGTDTSTTFPTLTKSPHETETRTTWLTHPAETSSTIPRTIPNFSHHESDATPSIA 10713 Query: 694 --------VTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPP----------- 734 + + TVS D T V + TIPT+ + P Sbjct: 10714 TSPGAETSSAIPIMTVSPGAEDLVTSQVTSSGTDRNMTIPTLTLSPGEPKTIASLVTHPE 10773 Query: 735 --SQPAVALSTIPGAVP--ITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKV 784 + A+ STI AV +T +T++AA + T +L++ G P + + Sbjct: 10774 AQTSSAIPTSTISPAVSRLVTSMVTSLAA---KTSTTNRALTNSPGEPATTVSL 10824 Score = 52.4 bits (124), Expect = 2e-06 Identities = 182/877 (20%), Positives = 309/877 (35%), Gaps = 161/877 (18%) Query: 25 VEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLI--------NPAATVNDESGRDSEVSA 76 VE S P L PST S PS I SG+ G +PA ++ G +S Sbjct: 1185 VETSRWNMPNL--PST-TSLTPSNIPTSGAIGKSTLVPLDTPSPATSLEASEGGLPTLST 1241 Query: 77 REHMSSSSSLQ--SREEKQEPV--------VVRP-------YPQVQ----MLSTHHAVAS 115 +++ S+ + + P VV+P +P ++ + + A +S Sbjct: 1242 YPESTNTPSIHLGAHASSESPSTIKLTMASVVKPGSYTPLTFPSIETHIHVSTARMAYSS 1301 Query: 116 ATPVAVTAPPAHLTPAV--PLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVT 173 + +TAP T + P ++ + PK T ++ P TL P + Sbjct: 1302 GSSPEMTAPGETNTGSTWDPTTY---ITTTDPKDTSSAQVSTPHSVRTLRTTENHPKTES 1358 Query: 174 VTME--SSIPQASAIP--------VATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGP-- 221 T S P+ S+ P TI+ H + LH+ +APGP Sbjct: 1359 ATPAAYSGSPKISSSPNLTSPATKAWTITDTTEHSTQLHYTKLAEKSSGFETQSAPGPVS 1418 Query: 222 -----PLHIGASHLPRGA---AAAAVMSSSKVTTVLRP--------------TSQLPNAA 259 IG+S L + V++ S+ TT+ P ++ L ++ Sbjct: 1419 VVIPTSPTIGSSTLELTSDVPGEPLVLAPSEQTTITLPMATWLSTSLTEEMASTDLDISS 1478 Query: 260 TAQPAVQHIIHQPIQS-RPPVTTSNAIPPAVVATVSATRAQ------------------S 300 + P I P+ + ++ S A A+ T S T Q + Sbjct: 1479 PSSPMSTFAIFPPMSTPSHELSKSEADTSAIRNTDSTTLDQHLGIRSLGRTGDLTTVPIT 1538 Query: 301 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSH-----PALGT 355 P+ TT + S ++ TLS P+ + + + + PSH P LGT Sbjct: 1539 PLTTTWTSVIEHSTQAQDTLSATMSPT---HVTQSLKDQTSIPASASPSHLTEVYPELGT 1595 Query: 356 PKQQLHTMAQKTIF---STGTPVAAATVAPILATNTIP-SATTAGSVSH----------- 400 Q + ++ T F ST T P +T P TT GS S Sbjct: 1596 ---QGRSSSEATTFWKPSTDTLSREIETGPTNIQSTPPMDNTTTGSSSSGVTLGIAHLPI 1652 Query: 401 -TQAPTSTIVTMTVPSHSSHATA--VTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLI 457 T +P T M + SS AT T + V + I+ + R+ + + Sbjct: 1653 GTSSPAETSTNMALERRSSTATVSMAGTMGLLVTSAPGRSISQSLGRVSSVLSESTTEGV 1712 Query: 458 PISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTP----------I 507 S +SP + T+ + S ++ Y + ++ PL + TP Sbjct: 1713 TDSSKGSSPR---LNTQGNTALSSSLEPSYAEGSQMSTSIPLTSSPTTPDVEFIGGSTFW 1769 Query: 508 TSSVSTIRQYPVSAQAPNSAITAQT--GVGVASTVHLNPMQLMTVDASHARHIQGIQPAP 565 T V+T+ +S + + ++ T + ST + +L T ++ P Sbjct: 1770 TKEVTTVMTSDISKSSARTESSSATLMSTALGSTENTGKEKLRTASMDLPSPTPSMEVTP 1829 Query: 566 ISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLAD 625 + + AP T + + G+H+++ + T + G T A L + Sbjct: 1830 WISLTLSNAPNTTDSLDL----SHGVHTSS--------AGTLATDRSLNTGVTRASRLEN 1877 Query: 626 GATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSE 685 G+ + +S S T++ T S++ + + P +T G + S Sbjct: 1878 GSDTSSKSLSMGNS---THTSMTYTEKSEVSSSIHPRPETSAPGAETTLTSTPGNRAISL 1934 Query: 686 IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQP--PPTIP-TMIAAASPPSQPAVALS 742 + PV E +S P I P P PPTI T +QP A+S Sbjct: 1935 TLPFSSIPVE---EVISTGITSGPDINSAPMTHSPITPPTIVWTSTGTIEQSTQPLHAVS 1991 Query: 743 TIPGAVPI--TPPITTIAAAPPP----SVTVGGSLSS 773 + +V TP + ++A + P SV+ G S SS Sbjct: 1992 SEKVSVQTQSTPYVNSVAVSASPTHENSVSSGSSTSS 2028 Score = 51.2 bits (121), Expect = 5e-06 Identities = 175/819 (21%), Positives = 305/819 (37%), Gaps = 154/819 (18%) Query: 78 EHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFS 137 E SSSSSL S P + P P V + P + + P HLT ++P S Sbjct: 6506 EKTSSSSSLLSL-----PAITSPSP----------VPTTLPESRPSSPVHLT-SLPTS-- 6547 Query: 138 EGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPG-----QVTVTMESSIPQASAIPVATIS 192 GL+K T +A PP+ S K+P + T M S A T S Sbjct: 6548 -GLVKT----TDMLASVASLPPNLGSTSHKIPTTSEDIKDTEKMYPSTNIAVTNVGTTTS 6602 Query: 193 GQQGH--------PSNLHHIMTT--NVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSS 242 ++ + P + M T N++ +I+ ++ PG +S + R + S+ Sbjct: 6603 EKESYSSVPAYSEPPKVTSPMVTSFNIRDTIVSTSMPG------SSEITR----IEMEST 6652 Query: 243 SKVTTVLR--PTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS 300 + L+ TSQ P +T + AV H + T+ A + S+ R Sbjct: 6653 FSLAHGLKGTSTSQDPIVSTEKSAVLHKL-----------TTGATETSRTEVASSRRTSI 6701 Query: 301 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQL 360 P H+T+S P +S + PS IS+ +S ++T I + P LG+ Q Sbjct: 6702 P----GPDHSTES----PDISTEVIPSLPISLGI-TESSNMT--IITRTGPPLGSTSQGT 6750 Query: 361 HTMAQKTIFSTGTPVAAATVA-------------PILATNTIPSATTAGSVSHTQAP--- 404 T+ T S + AT P + + TIP + S S + P Sbjct: 6751 FTLDTPTTSSRAGTHSMATQEFPHSEMTTVMNKDPEILSWTIPPSIEKTSFSSSLMPSPA 6810 Query: 405 -TSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHR 463 TS V+ T+P + TS + + V+ TSP P SS + H Sbjct: 6811 MTSPPVSSTLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSPEPTTSSPPNLSS----TSHE 6866 Query: 464 ---ASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVS 520 + A+E + + + + + LA T T+ + T + Sbjct: 6867 ILTTDEDTTAIEAMHPSTSTAATNVETTSSGHGSQSSVLADSEKTKATAPMDTTSTMGHT 6926 Query: 521 AQAPNSAITAQ-TGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTP 579 + + +++++ T + ST L P G++ IS Q A T Sbjct: 6927 TVSTSMSVSSETTKIKRESTYSLTP---------------GLRETSIS----QNASFSTD 6967 Query: 580 G---IQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISN 636 + P GT S T + + G P G + + VL + +T Sbjct: 6968 TSIVLSEVPTGTTAEVSRTEVTSSGRTSIP---------GPSQSTVLPEIST-------R 7011 Query: 637 PFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTV 696 + A+ T+ ++ + T GS+ + + L +T ++ K+ ++ P + Sbjct: 7012 TMTRLFASPTMTESAEMTIPTQTGPSGSTSQDT-LTLDTSTTKSQAKTHSTLTQRFPHSE 7070 Query: 697 SMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITP-PIT 755 +S D + P + + P ++P++++ + S P ++ ST+P + +P P+T Sbjct: 7071 MTTLMSRGPGDMSWQSSP--SLENPSSLPSLLSLPATTSPPPIS-STLPVTISSSPLPVT 7127 Query: 756 TIAAAPPPSVT--VGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLA 813 ++ + P + T + S V P +E R + T V PS Sbjct: 7128 SLLTSSPVTTTDMLHTSPELVTSSPPKLSHTSDE-------RLTTGKDTTNTEAVHPSTN 7180 Query: 814 LLANNLSMPTS--DLPPGA---SPRKKPRKQQHVISTEE 847 A+N+ +P+S + P A S K + ST+E Sbjct: 7181 TAASNVEIPSSGHESPSSALADSETSKATSPMFITSTQE 7219 Score = 50.8 bits (120), Expect = 7e-06 Identities = 157/810 (19%), Positives = 286/810 (35%), Gaps = 125/810 (15%) Query: 109 THHAVASATPVAVTAPPAHLTP---AVPLSFSEGLMKPPPKPTMPSRPIAPAP----PST 161 TH A P +V P P + P S PP S +P+P PS Sbjct: 9395 THSATTQRFPQSVVTTPMSRGPEDVSWPSPLSVEKNSPPSSLVSSSSVTSPSPLYSTPSG 9454 Query: 162 LSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGP 221 S VP VT S + +A+ + A++ + N++ +T++ ++ ++ Sbjct: 9455 SSHSSPVP--VTSLFTSIMMKATDMLDASLEPETTSAPNMN--ITSDESLAASKATTETE 9510 Query: 222 PLHI----GASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRP 277 +H+ ASH+ +A + SSS + PT + T+ +++ + Sbjct: 9511 AIHVFENTAASHVETTSATEELYSSSPGFS--EPTKVISPVVTSSSIRDNMVSTTMPGSS 9568 Query: 278 PVT-----TSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISI 332 +T + +++ P + T ++ S T+T + S + + PS+ SI Sbjct: 9569 GITRIEIESMSSLTPGLRETRTSQDITSSTETSTVLYKMPSGATPEVSRTEVMPSSRTSI 9628 Query: 333 QRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSA 392 PAQS T + + + T + + +T T + AT Sbjct: 9629 PGPAQS---TMSLDISDEVVTRLSTSPIMTESAEITITTQTGYSLAT------------- 9672 Query: 393 TTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIP-VAKVVPQQITHTSPR-IQPDYP 450 S P T +T +HS+ + ++ S + + P+ ++ TSPR ++ Sbjct: 9673 ------SQVTLPLGTSMTFLSGTHSTMSQGLSHSEMTNLMSRGPESLSWTSPRFVETTRS 9726 Query: 451 AERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSS 510 + + +P++ S +PV+ T D+ PS P+ + + + P TSS Sbjct: 9727 SSSLTSLPLT---TSLSPVS-STLLDSSPSSPLPVTSLILPGLVKTTEVLDTSSEPKTSS 9782 Query: 511 VSTIRQYPVSAQAPN-----------SAITAQTGVGVASTVHLNPMQLMT---------- 549 + V A + S+ TA V +S+VH + ++ Sbjct: 9783 SPNLSSTSVEIPATSEIMTDTEKIHPSSNTAVAKVRTSSSVHESHSSVLADSETTITIPS 9842 Query: 550 ---VDASHARHIQGIQPAPISTQGIQPAPIG--TPGIQPAPLG--------TQGIHSATP 596 A + PA T+ I P TPG + T + P Sbjct: 9843 MGITSAVDDTTVFTSNPAFSETRRIPTEPTFSLTPGFRETSTSEETTSITETSAVLYGVP 9902 Query: 597 IN--TQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQS 654 + T+ M + + + + D T V +S+ S+ + +T + +Q Sbjct: 9903 TSATTEVSMTEIMSSNRIHIPDSDQSTMSPDIITEVITRLSS--SSMMSESTQMTITTQK 9960 Query: 655 ASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMET--------VSNQNN 706 +S A AQ + + T P +H M T ++ S E V ++ Sbjct: 9961 SSPGATAQSTLTLATTTAPLARTHSTVPPRFLHSEMTTLMSRSPENPSWKSSLFVEKTSS 10020 Query: 707 DQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVT 766 +++P T P++ + + + P S +V PG V T S Sbjct: 10021 SSSLLSLPVTTS---PSVSSTLPQSIPSSSFSVTSLLTPGMVKTT----------DTSTE 10067 Query: 767 VGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTS-- 824 G SLS L EI EV T + PS ++ N+ +S Sbjct: 10068 PGTSLSPNLSGTSVEILAASEV-------------TTDTEKIHPSSSMAVTNVGTTSSGH 10114 Query: 825 DLPPGASPRKKPRKQQHVISTEEGDMMETN 854 +L S +P K + + T M ET+ Sbjct: 10115 ELYSSVSIHSEPSKATYPVGT-PSSMAETS 10143 Score = 47.4 bits (111), Expect = 7e-05 Identities = 167/852 (19%), Positives = 304/852 (35%), Gaps = 125/852 (14%) Query: 106 MLSTH--HAVASATPVAVTAPPAHLTPAVP------LSFSEGLMKPPPKPTMPSRPIAPA 157 M TH ++ T + +A P+HLT P S SE P SR I Sbjct: 1562 MSPTHVTQSLKDQTSIPASASPSHLTEVYPELGTQGRSSSEATTFWKPSTDTLSREIETG 1621 Query: 158 PPSTLSLPPKVPGQVTVTMESS---------IPQASAIPVATISGQQGHPSNLHHIMTTN 208 P + S PP T T SS +P ++ P T + + ++ Sbjct: 1622 PTNIQSTPPM---DNTTTGSSSSGVTLGIAHLPIGTSSPAETSTNMALERRSSTATVSMA 1678 Query: 209 VQMSIIRSNAPGPPLHIG---ASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAV 265 M ++ ++APG + S + + V SSK ++ R +Q A ++ Sbjct: 1679 GTMGLLVTSAPGRSISQSLGRVSSVLSESTTEGVTDSSKGSSP-RLNTQGNTALSSSLEP 1737 Query: 266 QHIIHQPIQSRPPVTTSNAIPPAV-----------VATV---------SATRAQSPVITT 305 + + + P+T+S P V TV + T + S + + Sbjct: 1738 SYAEGSQMSTSIPLTSSPTTPDVEFIGGSTFWTKEVTTVMTSDISKSSARTESSSATLMS 1797 Query: 306 TAAHATDSA-----------LSRPTLSIQHPPSAAISIQRP---AQSRDVTTRITLPSHP 351 TA +T++ L PT S++ P ++++ S D++ + S Sbjct: 1798 TALGSTENTGKEKLRTASMDLPSPTPSMEVTPWISLTLSNAPNTTDSLDLSHGVHTSSAG 1857 Query: 352 ALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVS-------HTQAP 404 L T + + + + G+ ++ +++ +T+T + T VS T AP Sbjct: 1858 TLATDRSLNTGVTRASRLENGSDTSSKSLSMGNSTHTSMTYTEKSEVSSSIHPRPETSAP 1917 Query: 405 TSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRA 464 + + P + + + + S+IPV +V+ IT + P I P S + P + Sbjct: 1918 GAETTLTSTPGNRAISLTLPFSSIPVEEVISTGIT-SGPDIN-SAPMTHSPITPPTIVWT 1975 Query: 465 SPNPVAMETR-----SDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQY-P 518 S + T+ S + SV Q ++ + SA P ++ ++S ST Y Sbjct: 1976 STGTIEQSTQPLHAVSSEKVSVQTQSTPYVNSVAVSASPTHENS---VSSGSSTSSPYSS 2032 Query: 519 VSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGT 578 S ++ +S I+ + + S + L T ST + G Sbjct: 2033 ASLESLDSTISRRN--AITSWLWDLTTSLPTTTWP-------------STSLSEALSSGH 2077 Query: 579 PGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVA---NPIS 635 G+ T + +T + T+ P+ ++ + D +++ P+ Sbjct: 2078 SGVSNPSSTTTEFPLFSAASTSAAKQRNPETETHGPQNTAASTLNTDASSVTGLSETPVG 2137 Query: 636 NPFSAAPAATTVVQTHSQ-----SASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSM 690 S+ + + S S ST P+ G++ S K + P SE VS Sbjct: 2138 ASISSEVPLPMAITSRSDVSGLTSESTANPSLGTA---SSAGTKLTRTISLPTSESLVSF 2194 Query: 691 ---ATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGA 747 P TVS+ S+ + T ++P + PP PS A ++ T+ + Sbjct: 2195 RMNKDPWTVSIPLGSHPTTNTET-SIPVNSAGPPGLSTVASDVIDTPSDGAESIPTVSFS 2253 Query: 748 VPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNT 807 +TTI+ P + ++SS+ E+ + P D M + P Sbjct: 2254 PSPDTEVTTISHFPEKTTHSFRTISSL----THELTSRVTPIPGDWMSSAMSTKPTG--- 2306 Query: 808 VSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLL 867 SPS+ L + P SP ++ T T S D+E + S + Sbjct: 2307 ASPSITL---GERRTITSAAPTTSP---------IVLTASFTETSTVSLDNETTVKTSDI 2354 Query: 868 VKAEKRKSPPKE 879 + A K P + Sbjct: 2355 LDARKTNELPSD 2366 Score = 47.4 bits (111), Expect = 7e-05 Identities = 152/790 (19%), Positives = 292/790 (36%), Gaps = 89/790 (11%) Query: 102 PQVQMLSTHHAVASATPVAVTAPPAHLTPAVP------LSFSEGLMKPPPKPTMPSRPIA 155 P+++ S + S+T + T P LT A ++ S P P + S I+ Sbjct: 4895 PKLRETSISQEITSSTETS-TVPYKELTGATTEVSRTDVTSSSSTSFPGPDQSTVSLDIS 4953 Query: 156 PAPPSTLSLPPKVP--GQVTVTMESSIPQASAIPVATISGQQGHP-SNLHHIMT---TNV 209 + LS P + ++T+T ++ A++ T+ P + +H MT + + Sbjct: 4954 TETNTRLSTSPIMTESAEITITTQTGPHGATSQDTFTMDPSNTTPQAGIHSAMTHGFSQL 5013 Query: 210 QMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHI- 268 ++ + S P + + ++ ++ +SS +TT +S LP + P + Sbjct: 5014 DVTTLMSRIPQDVSWTSPPSVDKTSSPSSFLSSPAMTTPSLISSTLPEDKLSSPMTSLLT 5073 Query: 269 -----IHQPIQSR-PPVTTS----NAIPPAVVATVSATRAQSPVITTTAAHATDSALSRP 318 I +++R PVT+S ++ ++AT ++ + + T+ + Sbjct: 5074 SGLVKITDILRTRLEPVTSSLPNFSSTSDKILATSKDSKDTKEIFPSINTEETNVKANNS 5133 Query: 319 TLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAA 378 P A + +TT + P+ P+ P +H ++ T Sbjct: 5134 GHESHSPALADSETPKATTQMVITTTVGDPA-PSTSMP---VHGSSETTNIKREPTYFLT 5189 Query: 379 TVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQI 438 +T+ S T S ++ PT TI ++ +S ++ ++T + + V P Sbjct: 5190 PRLRETSTSQESSFPTDTSFLLSKVPTGTITEVSSTGVNS-SSKISTPDHDKSTVPPDTF 5248 Query: 439 THTSPRIQPDYPAERSSLIPISGHRASPNPVAMET----------RSDNRPSVPVQFQYF 488 T PR+ +S+ + I+ + P + T + +V F Y Sbjct: 5249 TGEIPRVFTSSIKTKSAEMTITTQASPPESASHSTLPLDTSTTLSQGGTHSTVTQGFPYS 5308 Query: 489 LPTYPPSAYP--LAAHTYTPI--TSSVSTIRQYP-VSAQAPNSAITAQTGVGVASTVHLN 543 T P ++ T P+ TSSVS++ P +++ +P S+ + Q+ V Sbjct: 5309 EVTTLMGMGPGNVSWMTTPPVEETSSVSSLMSSPAMTSPSPVSSTSPQSIPSSPLPVTAL 5368 Query: 544 PMQLM--TVDASHARHIQGIQPAPISTQGI---QPAPIGTPGIQPAPLGTQGIHSATPIN 598 P ++ T D + + +P + I +PA A + + T + Sbjct: 5369 PTSVLVTTTDVLGTTSPESVTSSPPNLSSITHERPATYKDTAHTEAAMHHSTNTAVTNVG 5428 Query: 599 TQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTN 658 T G K+ + VLAD T A P+ + S + T + S + Sbjct: 5429 TSG------------SGHKSQSSVLADSETSKATPLMSTTSTLGDTSVSTSTPNISQTNQ 5476 Query: 659 APAQGSSPRPSILRKKPATDGAKPKSEIH----------VSMATPVTVSMETVSNQNNDQ 708 + ++ LR+ ++ +E + ++ A+ +S S + D+ Sbjct: 5477 IQTEPTASLSPRLRESSTSEKTSSTTETNTAFSYVPTGAITQASRTEISSSRTSISDLDR 5536 Query: 709 PTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVP--ITPPITTIAAAPPPSVT 766 PTIA P + + T +T PGA I P T+ ++ Sbjct: 5537 PTIA-PDISTGMITRLFTSPIMTKSAEMTVTTQTTTPGATSQGILPWDTS------TTLF 5589 Query: 767 VGGSLSSV-LGPPVPEIKVKEEVEPMDI----MRPV----SAVPPLATNTVSPSLALLAN 817 GG+ S+V G P EI P D+ PV S ++ + SPS + Sbjct: 5590 QGGTHSTVSQGFPHSEITTLRSRTPGDVSWMTTPPVEETSSGFSLMSPSMTSPSPVSSTS 5649 Query: 818 NLSMPTSDLP 827 S+P+S LP Sbjct: 5650 PESIPSSPLP 5659 Score = 45.4 bits (106), Expect = 3e-04 Identities = 162/742 (21%), Positives = 249/742 (33%), Gaps = 106/742 (14%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVV 97 PST S A S +S + + V G S + ++SS+ L S + Sbjct: 3580 PSTWSSTAAS---DSWTVTDMTSNLKVARSPGTISTMHTTSFLASSTELDSMSTPHGRIT 3636 Query: 98 VRPYPQVQMLSTHHAVASATPVAV-TAPPAHLTPAVPLS-FSEGLMKPPPKPTMPSRPIA 155 V V S AV + T + T P+ T + P+S FS P + S Sbjct: 3637 VIGTSLVTPSSDASAVKTETSTSERTLSPSDTTASTPISTFSRVQRMSISVPDILSTSWT 3696 Query: 156 PAPPSTLSLP--------------PKVPGQVTV-----TMESSIPQASAIPVATISGQQG 196 P+ +P P P + T++ ++ + AT S QG Sbjct: 3697 PSSTEAEDVPVSMVSTDHASTKTDPNTPLSTFLFDSLSTLDWDTGRSLSSATATTSAPQG 3756 Query: 197 HPSNLHHIMTTNVQMSIIRSNAPGP---PLHIGASHLPRGAAAAAVMSSSKVT-TVLRPT 252 TT ++++ +P P IG H+ AA+ SS VT + PT Sbjct: 3757 --------ATTPQELTLETMISPATSQLPFSIG--HITSAVTPAAMARSSGVTFSRPDPT 3806 Query: 253 SQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATD 312 S+ + Q H R TT + IP + + Q TT A AT Sbjct: 3807 SKKAEQTSTQLPTTTSAHPGQVPRSAATTLDVIPHTAKTPDATFQRQGQTALTTEARATS 3866 Query: 313 SALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSH--PALGTPKQQLHTMA------ 364 + + S P + I+ + S D +T S L T L + Sbjct: 3867 DSWNEKEKST--PSAPWITEMMNSVSEDTIKEVTSSSSVLRTLNTLDINLESGTTSSPSW 3924 Query: 365 QKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVT 424 + + + P + T + +T TT S A STI P+HS A++ Sbjct: 3925 KSSPYERIAPSESTTDKEAIHPSTNTVETTGWVTSSEHASHSTI-----PAHS--ASSKL 3977 Query: 425 TSNIPVAKVVPQQITHTSPRIQPDYP---AERSSLIPISGHRASPNPVAMETRSDNRPSV 481 TS + Q I S P+ E +S + I SP M+T S + S+ Sbjct: 3978 TSPVVTTSTREQAIVSMSTTTWPESTRARTEPNSFLTIELRDVSP---YMDTSSTTQTSI 4034 Query: 482 PVQFQYFLPTYPPSAYPLAAHTYTPITS----SVSTIRQYPVSAQAPNSAITAQTGVGVA 537 P + + T ITS S S + Q S+ +P+ AIT Sbjct: 4035 ---------ISSPGSTAITKGPRTEITSSKRISSSFLAQSMRSSDSPSEAIT-------- 4077 Query: 538 STVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPI 597 L+ MT +Q P S T PL T + + Sbjct: 4078 ---RLSNFPAMTESGGMILAMQTSPPGATSLSAPTLDTSATASWTGTPLATTQRFTYSE- 4133 Query: 598 NTQGLQPAPMGTQQPQP-----EGKTSAVVLADGATIVANPISNPFSAAPAATTVV---- 648 T P T QP P +S++V T +N + +P++T V Sbjct: 4134 KTTLFSKGPEDTSQPSPPSVEETSSSSSLVPIHATTSPSNILLTSQGHSPSSTPPVTSVF 4193 Query: 649 --QTHSQSASTNAPAQGSSPRPSILRKKPATDG--------AKPKSEIHVSMATPVTVSM 698 +T +T+ P S+ +T G ++ IH S T VT +M Sbjct: 4194 LSETSGLGKTTDMSRISLEPGTSLPPNLSSTAGEALSTYEASRDTKAIHHSADTAVT-NM 4252 Query: 699 ETVSNQNNDQPTIAVPPTAQQP 720 E S++ + P P A P Sbjct: 4253 EATSSEYSPIPGHTKPSKATSP 4274 Score = 45.4 bits (106), Expect = 3e-04 Identities = 182/907 (20%), Positives = 315/907 (34%), Gaps = 171/907 (18%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDE--SGRDSEVSAREHMSSSSSLQSREEKQ-- 93 P++ L+ + + S L A TV + +G +EVS E +S S + S E+ Sbjct: 7536 PASSLTTRLRETSTSEETSLATEANTVLSKVSTGATTEVSRTEAISFSRTSMSGPEQSTM 7595 Query: 94 -EPVVVRPYPQVQMLSTHHAVASATPVAVTAPPA-------HLTPAVPLSFSEG---LMK 142 + + + P++ S A T T P +L A S+ E +++ Sbjct: 7596 SQDISIGTIPRISASSVLTESAKMTITTQTGPSESTLESTLNLNTATTPSWVETHSIVIQ 7655 Query: 143 PPPKPTM-------------PSRPIAP--APPST-LSLPPKV-PGQVTVTMESSIPQASA 185 P P M PS P +PPS+ LSLP P V+ T + IP S Sbjct: 7656 GFPHPEMTTSMGRGPGGVSWPSPPFVKETSPPSSPLSLPAVTSPHPVSTTFLAHIPP-SP 7714 Query: 186 IPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKV 245 +PV ++ P+ I+ T+ + S++ H + A AV S+ Sbjct: 7715 LPVTSLL--TSGPATTTDILGTSTEPGTSSSSSLSTTSHERLTTYKDTAHTEAVHPSTNT 7772 Query: 246 TTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSA----TRAQSP 301 N AT + S P TTS +V+ + A R Q+ Sbjct: 7773 GGT--------NVATTSSGYKSQSSVLADSSPMCTTSTMGDTSVLTSTPAFLETRRIQTE 7824 Query: 302 VITT--------TAAHATDSALSRPTLSIQHPPSAAISIQR--------PAQSR---DVT 342 + ++ + + T S T+ + P A I + PAQS D++ Sbjct: 7825 LASSLTPGLRESSGSEGTSSGTKMSTVLSKVPTGATTEISKEDVTSIPGPAQSTISPDIS 7884 Query: 343 TR-ITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATN-TIPSATTAGSVSH 400 TR ++ S + T ++ TM T T +T+ T+ T+ +T + SH Sbjct: 7885 TRTVSWFSTSPVMTESAEI-TMNTHTSPLGATTQGTSTLDTSSTTSLTMTHSTISQGFSH 7943 Query: 401 TQAPT-------------STIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQP 447 +Q T ++ T PS S ++ TTS PV+ +P+ I+ Sbjct: 7944 SQMSTLMRRGPEDVSWMSPPLLEKTRPSFSLMSSPATTSPSPVSSTLPESIS-------- 7995 Query: 448 DYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPI 507 SS +P++ S +A T ++ S PV P + + Sbjct: 7996 ------SSPLPVTSLLTS--GLAKTTDMLHKSSEPV------TNSPANLSSTSVEILATS 8041 Query: 508 TSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPIS 567 + T + +P S+ T VG +S+ H + D+ ++ + + Sbjct: 8042 EVTTDTEKTHP-------SSNRTVTDVGTSSSGH-ESTSFVLADSQTSK----VTSPMVI 8089 Query: 568 TQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGA 627 T ++ + T T G + I T+ +G + KTS + Sbjct: 8090 TSTMEDTSVST--------STPGFFETSRIQTEPTSSLTLGLR------KTS----SSEG 8131 Query: 628 TIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIH 687 T +A +S S P T + ++ S+ S Sbjct: 8132 TSLATEMSTVLSGVPTGATAEVSRTEVTSS--------------------------SRTS 8165 Query: 688 VSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGA 747 +S +TVS ET + PT ++ + + T ++P S V +ST P Sbjct: 8166 ISGFAQLTVSPETSTETITRLPTSSIMTESAEMMIKTQTDPPGSTPESTHTVDISTTPNW 8225 Query: 748 VPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNT 807 V +T + + V S +L P ++ + + ++ P+++ Sbjct: 8226 VETHSTVTQRFSHSEMTTLVSRSPGDMLWPSQSSVEETSSASSLLSLPATTSPSPVSSTL 8285 Query: 808 VS--PSLALLANNLSMP----TSD-----LPPGASPRKKPRKQQHVISTEEGDMMETNST 856 V PS +L +L P T+D PG S H T D ++T Sbjct: 8286 VEDFPSASLPVTSLLNPGLVITTDRMGISREPGTSSTSNLSSTSHERLTTLEDTVDTEDM 8345 Query: 857 DDEKSTA 863 TA Sbjct: 8346 QPSTHTA 8352 Score = 38.5 bits (88), Expect = 0.033 Identities = 159/748 (21%), Positives = 267/748 (35%), Gaps = 119/748 (15%) Query: 147 PTMPSRPIAPAPPSTLSLP-PKVPGQVTVTMESSIPQASAIPVATISGQQ--GHPSNLHH 203 PT S A + PS S P+VP T T ++ P S+ + G G PS L Sbjct: 2393 PTSISGMTASSSPSLFSSDRPQVPTSTTETNTATSPSVSSNTYSLDGGSNVGGTPSTLPP 2452 Query: 204 IMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAA--VMSSSKVTTVLRP--------TS 253 T+ + A P+ ++ + A+ S+S VT+V P T+ Sbjct: 2453 FTITHPVETSSALLAWSRPVRTFSTMVSTDTASGENPTSSNSVVTSVPAPGTWTSVGSTT 2512 Query: 254 QLPNAATAQPAVQHIIHQPIQSR-PPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATD 312 LP + + H + S P T A V T S+ +++ ++TT+ + A Sbjct: 2513 DLPAMGFLKTSPAGEAHSLLASTIEPATAFTPHLSAAVVTGSSATSEASLLTTSESKAIH 2572 Query: 313 SALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTG 372 S+ PT P S A + TP+ L + +T +T Sbjct: 2573 SSPQTPTT----PTSGA-------------------NWETSATPESLL--VVTETSDTTL 2607 Query: 373 TPVAAATVAPILATNTIPSA--TTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPV 430 T T + +T + P + + G++S PT T +P ++ T+ ++ Sbjct: 2608 TSKILVTDTILFSTVSTPPSKFPSTGTLSGASFPTLLPDTPAIPLTATEPTSSLATSFDS 2667 Query: 431 AKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVP---VQFQY 487 +V I S P+ S ++ + + ++T S+ S+P +Q Sbjct: 2668 TPLV--TIASDSLGTVPETTLTMS-------ETSNGDALVLKTVSNPDRSIPGITIQGVT 2718 Query: 488 FLPTYPPSAYP--LAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPM 545 P +P S P + A T S+ T+ + A S + +Q+ +T Sbjct: 2719 ESPLHPSSTSPSKIVAPRNTTYEGSI-TVALSTLPAGTTGSLVFSQSSENSETTA----- 2772 Query: 546 QLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPA 605 VD+S + P +QG+ + GI+ + G T+ Sbjct: 2773 ---LVDSSAGLERASVMPLTTGSQGM----ASSGGIRSGSTHSTG--------TKTFSSL 2817 Query: 606 PMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSS 665 P+ T P G+ +A+ + I N ++ S AP V T ++S + SS Sbjct: 2818 PL-TMNP---GEVTAM-----SEITTNRLTATQSTAPKGIPVKPTSAESGLLTPVSASSS 2868 Query: 666 PRPSI--LRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPT 723 P + L P T G P+S + + S++T S A PT Q T Sbjct: 2869 PSKAFASLTTAPPTWGI-PQSTLTFEFSE--VPSLDTKS---------ASLPTPGQSLNT 2916 Query: 724 IPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSV-------TVGGSLSSVLG 776 IP S S + +LS P P +T+ A S T GS S + Sbjct: 2917 IPD-----SDASTASSSLSKSPEKNPRARMMTSTKAISASSFQSTGFTETPEGSASPSMA 2971 Query: 777 PPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKP 836 P + +P +S P ++ S +L S T+ G + R Sbjct: 2972 GHEPRVPTSGTGDPRYASESMSYPDPSKASSAMTSTSL----ASKLTTLFSTGQAARSGS 3027 Query: 837 RKQQHVISTEEGDMMETNSTDDEKSTAK 864 +STE+ ET+ ST++ Sbjct: 3028 SSSPISLSTEK----ETSFLSPTASTSR 3051 Score = 36.6 bits (83), Expect = 0.13 Identities = 143/753 (18%), Positives = 266/753 (35%), Gaps = 108/753 (14%) Query: 38 PSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSR---EEKQE 94 P +SQA + S +A + V E + + S QS EE Sbjct: 5867 PIGTISQATLTLDTSSTASWEGTHSPVTQRFPHSEETTTMSRSTKGVSWQSPPSVEETSS 5926 Query: 95 PVVVRPYPQVQMLST-HHAVASATPVAVTAPPAHLTPAVPLS--FSEGLMKPPPKPTMPS 151 P P P + S+ + AV+ ++P T A+P++ + G K S Sbjct: 5927 PSSPVPLPAITSHSSLYSAVSGSSP----------TSALPVTSLLTSGRRKTIDMLDTHS 5976 Query: 152 RPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQM 211 + + PS S ++ T +I S T G LH ++ + Q Sbjct: 5977 ELVTSSLPSASSFSGEILTSEASTNTETI-HFSENTAETNMGTTNSMHKLHSSVSIHSQP 6035 Query: 212 S---------------IIRSNAPGPPLHIGASH---------LPRGAAAAAVMSSSKVTT 247 S I+ ++ PG P L + A + S+++ T Sbjct: 6036 SGHTPPKVTGSMMEDAIVSTSTPGSPETKNVDRDSTSPLTPELKEDSTALVMNSTTESNT 6095 Query: 248 VLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTA 307 V S +AAT + + P + P + + P + S++ + SP +T + Sbjct: 6096 VFSSVSL--DAATEVSRAEVTYYDP--TFMPASAQSTKSPDISPEASSSHSNSPPLTIS- 6150 Query: 308 AHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTP----------- 356 + T++ Q PS S+ + + D +T T P+ T Sbjct: 6151 --------THKTIATQTGPSGVTSLGQ--LTLDTSTIATSAGTPSARTQDFVDSETTSVM 6200 Query: 357 KQQLHTMAQKTIFSTGTPVAAATVAPILAT-------NTIPSATTAGSVSHTQAPTSTIV 409 L+ + + + FS + ++ AP+L T +T+ +T+ VS T PT T+ Sbjct: 6201 NNDLNDVLKTSPFSAEEANSLSSQAPLLVTTSPSPVTSTLQEHSTSSLVSVTSVPTPTLA 6260 Query: 410 TMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPV 469 +T + + N+ + T T +P+ +++ + G +SPN Sbjct: 6261 KITDMDTNLEPVTRSPQNLRNTLATSEATTDTHTM----HPSINTAVANV-GTTSSPNEF 6315 Query: 470 AMETRSDNRP--------SVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSA 521 D+ P + T P + + S + +R+ S Sbjct: 6316 YFTVSPDSDPYKATSAVVITSTSGDSIVSTSMPRSSAMKKIESETTFSLIFRLRETSTSQ 6375 Query: 522 QAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPI----STQGIQPAP-- 575 + +S+ T+ T A T + + +S IQG + + ST+ + Sbjct: 6376 KIGSSSDTS-TVFDKAFTAATTEVSRTELTSSSRTSIQGTEKPTMSPDTSTRSVTMLSTF 6434 Query: 576 IGTPGIQPAPLGTQ-GIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPI 634 G + + TQ G H AT T + +Q T D +T+ + Sbjct: 6435 AGLTKSEERTIATQTGPHRATSQGTLTWDTSITTSQAGTHSAMTHGFSQLDLSTLTSR-- 6492 Query: 635 SNPFSAAPAATTVVQTHSQSASTNAPAQGS-SPRPSILRKKPATDGAKPKSEIHVSMATP 693 + + + +V +T S S+ + PA S SP P+ L + ++P S +H++ + P Sbjct: 6493 VPEYISGTSPPSVEKTSSSSSLLSLPAITSPSPVPTTLPE------SRPSSPVHLT-SLP 6545 Query: 694 VTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPT 726 + ++T + ++PP IPT Sbjct: 6546 TSGLVKTTDMLAS---VASLPPNLGSTSHKIPT 6575 Score = 32.7 bits (73), Expect = 1.8 Identities = 160/862 (18%), Positives = 297/862 (34%), Gaps = 146/862 (16%) Query: 39 STGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVV 98 S GL +A +GS G+ A++ SG S+ S ++ P+ + Sbjct: 2777 SAGLERASVMPLTTGSQGM---ASSGGIRSG------------STHSTGTKTFSSLPLTM 2821 Query: 99 RPYPQVQM--LSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIA- 155 P M ++T+ A+ + TAP P P S GL+ P + PS+ A Sbjct: 2822 NPGEVTAMSEITTNRLTATQS----TAPKG--IPVKPTSAESGLLTPVSASSSPSKAFAS 2875 Query: 156 --PAPP------STLSLP-PKVPGQVTVTME--------SSIPQASAIPVATISGQQGHP 198 APP STL+ +VP T + ++IP + A ++ + Sbjct: 2876 LTTAPPTWGIPQSTLTFEFSEVPSLDTKSASLPTPGQSLNTIPDSDASTASSSLSKSPEK 2935 Query: 199 SNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNA 258 + +MT+ +S + G + P G+A+ ++ ++P + Sbjct: 2936 NPRARMMTSTKAISASSFQS------TGFTETPEGSASPSMAGHE---------PRVPTS 2980 Query: 259 ATAQP--AVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRA------QSPVITTTAAHA 310 T P A + + + TS ++ + S +A SP+ +T Sbjct: 2981 GTGDPRYASESMSYPDPSKASSAMTSTSLASKLTTLFSTGQAARSGSSSSPISLSTEKET 3040 Query: 311 T----DSALSRPTL-----SIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLH 361 + ++ SR T S+ P+ + +Q A + T+ + + Q Sbjct: 3041 SFLSPTASTSRKTSLFLGPSMARQPNILVHLQTSALTLSPTSTLNMSQEEPPELTSSQTI 3100 Query: 362 TMAQKTIFSTGTPVAAATVAPILATNTIP-SATTAGSVSHTQAPTSTIVTMTVPSHSSHA 420 + T T T + P T+ +P S+ T + +P + +++VP+ +S Sbjct: 3101 AEEEGTTAETQTLTFTPSETP---TSLLPVSSPTEPTARRKSSPETWASSISVPAKTSLV 3157 Query: 421 TAVTTSNIPVAKVVPQ--QITHTSPRIQPDYPAERSSLIPISGHRASPN-PVAMETRSDN 477 + + K+ Q Q T P PAE + P SP ++ S Sbjct: 3158 ETTDGTLVTTIKMSSQAAQGNSTWPA-----PAEETGSSPAGTSPGSPEMSTTLKIMSSK 3212 Query: 478 RPSVPVQFQYFLPTYP---PSAYPLAAHTYTPIT-------SSVSTIRQYPVSAQAPNSA 527 PS+ + + + P P T P+T S ++I P +P + Sbjct: 3213 EPSISPEIRSTVRNSPWKTPETTVPMETTVEPVTLQSTALGSGSTSISHLPTGTTSPTKS 3272 Query: 528 ITAQ---------------------TGVGVASTVHLNPMQLMTVDASHARHIQGI--QPA 564 T +G + L M +++++ AR I G Q + Sbjct: 3273 PTENMLATERVSLSPSPPEAWTNLYSGTPGGTRQSLATMSSVSLESPTARSITGTGQQSS 3332 Query: 565 P---ISTQGIQ-----PAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEG 616 P T G++ + GT G L T P+ + P + + + + Sbjct: 3333 PELVSKTTGMEFSMWHGSTGGTTGDTHVSLSTSSNILEDPVTS----PNSVSSLTDKSKH 3388 Query: 617 KTSAVVLADGATIVANPISNPFSAAPAAT--TVVQTHSQSASTNAPAQGS----SPRPSI 670 KT V I + ++N AA T +V + +S ++S + GS P + Sbjct: 3389 KTETWV--STTAIPSTVLNNKIMAAEQQTSRSVDEAYSSTSSWSDQTSGSDITLGASPDV 3446 Query: 671 LRKKPATDGAKPKSEIHVSMATPVTVSMETVS-NQNNDQPTIAVPPTAQQPPPTIPTMIA 729 T A+ S + + S+ S + + ++ P + + + Sbjct: 3447 TNTLYITSTAQTTSLVSLPSGDQGITSLTNPSGGKTSSASSVTSPSIGLETLRANVSAVK 3506 Query: 730 AASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVE 789 + P+ ++ ++ P V I T ++T G+ S P PE+ Sbjct: 3507 SDIAPTAGHLSQTSSPAEVSILDVTTAPTPGISTTITTMGTNSISTTTPNPEV------- 3559 Query: 790 PMDIMRPVSAVPPLATNTVSPS 811 M M A T+T PS Sbjct: 3560 GMSTMDSTPATERRTTSTEHPS 3581 >gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] Length = 2089 Score = 82.0 bits (201), Expect = 3e-15 Identities = 212/987 (21%), Positives = 330/987 (33%), Gaps = 171/987 (17%) Query: 5 RHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINPAATV 64 R Q GE E GG + Q +S P G + L S SGS Sbjct: 944 RDTQRGEPE-----GGSQDQKGQASSPTPEPGVGAGDLPGPTSAPVPSGS---------- 988 Query: 65 NDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAP 124 GR S VS R H + + ++ +R +V A P T P Sbjct: 989 -QSGGRGSPVSPRRHQKGLLNCKM-PPAEKASRIRAAEKVSRGDQESPDACLPP---TVP 1043 Query: 125 PAHLTPAVPL-SFSEGLMKPPP--KPTMPS-RPI-----------APAPPSTLSLPPKVP 169 A P PL S S+ + PPP P +PS +P AP P + L P P Sbjct: 1044 EAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHP 1103 Query: 170 GQVTVTMESS----IPQASAIPV---ATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPP 222 T +SS P SA P +T + Q P + S +++ P P Sbjct: 1104 KPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVP 1163 Query: 223 LHIGASHLPRGAAAAAVMSSSKVTTVLR----------PTSQLPNAATAQPAVQHIIHQP 272 A L + ++S + V R P + +P A QP+ +P Sbjct: 1164 T---APELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTS--TDRP 1218 Query: 273 IQSRPP------------VTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTL 320 + S P V T + P +T PV + AT +R ++ Sbjct: 1219 VTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSV 1278 Query: 321 SIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKT-IFSTGTPVAAAT 379 P RP+ S D TPK T +T + S TP Sbjct: 1279 KTPEPVVPTAPELRPSTSTDRPV-----------TPKPTSRTTRSRTNMSSVKTPETVVP 1327 Query: 380 VAPILATNTI--------PSATTAGS---VSHTQAPTSTI-VTMTVPSHSSHATAVTTSN 427 AP L +T P++ T S +S + P ST+ + +P +S VT Sbjct: 1328 TAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPE- 1386 Query: 428 IPVAKV-----------VPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRS- 475 P ++ P+ + T+P+++P ++ +P P + TR Sbjct: 1387 -PTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQP---------VTPEPTSQATRGR 1436 Query: 476 DNRPSVPVQFQYFLPTYP---PSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITA-- 530 NR SV + +PT P PS T P TS + R S + P + + Sbjct: 1437 TNRSSVKTP-ETVVPTAPELQPSTSTDQPVTPEP-TSQATRGRTDRSSVKTPETVVPTAP 1494 Query: 531 --QTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPL-- 586 Q V P T + ++ + + +QP+ + P P Sbjct: 1495 ELQASASTDQPVTSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSR 1554 Query: 587 GTQGIHSATPINT--------QGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPIS-NP 637 T+G + + + T LQP+ Q PE + A + V P P Sbjct: 1555 ATRGRTNRSSVKTPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVP 1614 Query: 638 FSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVS 697 + P TT T+ + + R S+ KP A S++ T +V+ Sbjct: 1615 TAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAA---SDLEPFTPTDQSVT 1671 Query: 698 METVSNQNNDQ---------------PTIAVPPTAQQP----PPTIPTMI---AAASPPS 735 E ++ + P P T QP P T P+ I AA P Sbjct: 1672 PEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPG 1731 Query: 736 QPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMR 795 A + P + P+ P +V SL+++ P P++ +E Sbjct: 1732 SLAAPIDHKPCSAPLEPKSQASRNQRWGAVRAAESLTAIPEPASPQL-----LETPIHAS 1786 Query: 796 PVSAVPPLATNTVSPSL---ALLANNLSMPTSDLPPGASPRKKPRKQQH--VISTEEGDM 850 + V P + +P L A + S+ T D PP ++ Q +I EE D Sbjct: 1787 QIQKVEPAGRSRFTPELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDT 1846 Query: 851 METNSTDDEKSTAKSLLVKAEKRKSPP 877 E +++ T K K ++ + P Sbjct: 1847 AEKPGKEEDVVTPKPGKRKRDQAEEEP 1873 >gi|161019170 mucin 5AC [Homo sapiens] Length = 6207 Score = 79.7 bits (195), Expect = 1e-14 Identities = 156/721 (21%), Positives = 249/721 (34%), Gaps = 118/721 (16%) Query: 114 ASATPV---AVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPG 170 A+A P T P A A+P S + T P+ ++ A PS S P V Sbjct: 3157 ATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPS--STPETVHT 3214 Query: 171 QVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGP----PLHIG 226 +T ++ A+ VAT S G + TT + S++PG P+ I Sbjct: 3215 STVLTTTATTTGATG-SVATPSSTPGTAHTTKVLTTTTTGFTATPSSSPGTARTLPVWIS 3273 Query: 227 ASHLPRGAAAAAVMSS------------SKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQ 274 + P + SS + TTV + P+++T H P+ Sbjct: 3274 TTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHT--PPVP 3331 Query: 275 SRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQR 334 + T ++ P+ TV + T H T+ P+ H P+A Sbjct: 3332 NTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITE-----PSTGTSHTPAA------ 3380 Query: 335 PAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATT 394 TT T S PAL +P T T TP + AT T PS T Sbjct: 3381 -------TTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATAT-PSKTR 3432 Query: 395 AGSV---SHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPD-YP 450 ++ S T AP +T+VTM + + + + ++ P P Sbjct: 3433 TSTLLPSSPTSAPITTVVTMGCEPQCAWS---------------EWLDYSYPMPGPSGGD 3477 Query: 451 AERSSLIPISGHRASPNPVAMETRSDNRPSVPVQ-------------------------- 484 + S I +G P+ +E R+ +P VP++ Sbjct: 3478 FDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLRELGQVVECSLDFGLVCRNREQVGKFK 3537 Query: 485 --FQYFLPTY------PPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGV 536 F Y + + PS P + T TP ++ +T + A +A T T + Sbjct: 3538 MCFNYEIRVFCCNYGHCPST-PATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPS 3596 Query: 537 ASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGT--------PGIQPAPLGT 588 ++ P +++T A+ + S + P+ T P P T Sbjct: 3597 STPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFT 3656 Query: 589 QGIHSATPINTQGLQPAPMGTQQPQ--PEGKTSAVVLADGATIVANPISNPFSAAPAATT 646 G P T A M T P PE ++ VL AT S ++ TT Sbjct: 3657 LGTTGTLPEQTT-TPMATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTT 3715 Query: 647 VVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNN 706 + T +A+T A G + PS P T + ++ P T S T S+ Sbjct: 3716 WILTELTTAATTTAATGPTATPS---STPGTTWILTEPSTTATVTVP-TGSTATASSTRA 3771 Query: 707 DQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPG--AVPITPPITTIAAAPPPS 764 T+ V + T PT+I++ + PS + +P + TP T++ A P S Sbjct: 3772 TAGTLKVLTST----ATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSS 3827 Query: 765 V 765 + Sbjct: 3828 L 3828 Score = 77.8 bits (190), Expect = 5e-14 Identities = 154/673 (22%), Positives = 236/673 (35%), Gaps = 82/673 (12%) Query: 115 SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTV 174 +++P APPA T AVP + SEGL P T+ + S P VPG T Sbjct: 2327 TSSPGLTRAPPASTT-AVP-TLSEGLTSPRYTSTLGTATTGGPTTPAGSTEPTVPGVAT- 2383 Query: 175 TMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGA 234 S++P SA+P T S PS + T + S R AS P Sbjct: 2384 ---STLPTRSALPGTTGSLGTWRPSQPPTLAPTTMATSRARPTGTAST----ASKEPLTT 2436 Query: 235 AAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVT----------TSNA 284 + A + +S+++T TS T P Q P ++ Sbjct: 2437 SLAPTL-TSELSTSQAETSTPRTETTMSPLTNTTTSQGTTRCQPKCEWTEWFDVDFPTSG 2495 Query: 285 IPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPP---SAAISIQRPAQSRDV 341 + + T RA + A + P +SI + ++ ++ D Sbjct: 2496 VAGGDMETFENIRAAGGKMCWAPKSIECRAENYPEVSIDQVGQVLTCSLETGLTCKNEDQ 2555 Query: 342 TTRITL--PSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVS 399 T R + + + H + ST TP + IL T +ATT S Sbjct: 2556 TGRFNMCFNYNVRVLCCDDYSHCPSTPATSSTATPSSTPGTTWIL-TKPTTTATTTASTG 2614 Query: 400 HTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPI 459 T PTST+ T P T TT + +K P +SP PA RS+ Sbjct: 2615 STATPTSTL--RTAPPPKVLTTTATTPTVTSSKATPS----SSPGTATALPALRSTATTP 2668 Query: 460 SGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPV 519 + +P P + + R S + T PS+ P AHT T +T++ +T Sbjct: 2669 TATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATT------ 2722 Query: 520 SAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTP 579 A S T + G A T + +T G P +P Sbjct: 2723 -TGATGSVATPSSTPGTAHTTKV---------------------PTTTTTGFTATPSSSP 2760 Query: 580 GIQPAPLGTQGIHSATPINTQGLQPAPM---GTQQPQPEGKTSAVVLADGATIVANPISN 636 G P I + T T+G P GT T+ +A G+ +A P S+ Sbjct: 2761 GTALTP--PVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGS--MATPSSS 2816 Query: 637 PFSAA-----PAATTVVQTHSQSASTNAP----AQGSSPRPSILRKKPATDGAKPKSEIH 687 ++ P T+ TH +S ++P +S IL T+ + S H Sbjct: 2817 TQTSGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTS--H 2874 Query: 688 VSMATPVTVSMET--VSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPA-VALSTI 744 AT T T +S+ + T PP+ P T + + + P+ ST+ Sbjct: 2875 TLAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTL 2934 Query: 745 PGAVPITPPITTI 757 + P + PITT+ Sbjct: 2935 LPSSPTSAPITTV 2947 Score = 77.8 bits (190), Expect = 5e-14 Identities = 173/815 (21%), Positives = 273/815 (33%), Gaps = 146/815 (17%) Query: 114 ASATPV---AVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPG 170 A+A P T P A A+P S + T P+ ++ A PS+ P+ Sbjct: 4304 ATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSST---PETAH 4360 Query: 171 QVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPG----PPLHIG 226 TV ++ + VAT S G TT ++ S++PG PP+ I Sbjct: 4361 TSTVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWIS 4420 Query: 227 ASHLPRGAAAAAVMSS------------SKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQ 274 + P + + SS + TTV + P+++T H P+ Sbjct: 4421 TTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHT--PPVP 4478 Query: 275 SRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQR 334 + T ++ P+ TV + T H T+ P+ H P+A Sbjct: 4479 NTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITE-----PSTGTSHTPAA------ 4527 Query: 335 PAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATT 394 TT T S PAL +P P + T +P T P TT Sbjct: 4528 -------TTGTTQHSTPALSSPH----------------PSSRTTESPPSPGTTTPGHTT 4564 Query: 395 AGS-VSHTQAPTSTIVTMTVPSHSSHA--TAVTTSNIPVAKVVPQQITHTSPRIQPD-YP 450 A S + T P+ T + +PS + A T V T+ + + ++ P P Sbjct: 4565 ATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGD 4624 Query: 451 AERSSLIPISGHRASPNPVAMETRSDNRPSVPV--------------------------- 483 + S I +G P+ +E R+ +P VP+ Sbjct: 4625 FDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFK 4684 Query: 484 -----QFQYFLPTYP--PSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGV 536 + + F Y PS P + T P ++ +T ++ A +A T T Sbjct: 4685 MCFNYEIRVFCCNYGHCPST-PATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPS 4743 Query: 537 ASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGT--------PGIQPAPLGT 588 ++ P +++T A+ + S + P+ T + P P T Sbjct: 4744 STPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSST 4803 Query: 589 QGIHSATPINTQGLQPAPMGTQQPQ--PEGKTSAVVLADGATIVANPISNPFSAAPAATT 646 G P T A M T P PE ++ VL AT S ++ TT Sbjct: 4804 LGTTGTLPEQTT-TPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTT 4862 Query: 647 VVQTHSQSASTNAPAQGSSPRPS-------ILRKKPAT--------DGAKPKSE------ 685 + T +A+T A G + PS IL + T A P S Sbjct: 4863 WILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWI 4922 Query: 686 -IHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTI 744 S VTV + + ++ Q T P + T PT+ ++ + PS + + Sbjct: 4923 LTEPSTTATVTVPTGSTATASSTQATAGTPHVS--TTATTPTVTSSKATPSSSPGTATAL 4980 Query: 745 PG--AVPITPPITTIAAAPPPSV-TVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVP 801 P + TP T+ A P S+ T LS P M P S Sbjct: 4981 PALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTP----------TATMSTATPSSTPE 5030 Query: 802 PLATNTVSPSLALLANNL-SMPTSDLPPGASPRKK 835 + T+TV + A S+ T PG + K Sbjct: 5031 TVHTSTVLTATATTTGATGSVATPSSTPGTAHTTK 5065 Score = 73.2 bits (178), Expect = 1e-12 Identities = 157/762 (20%), Positives = 254/762 (33%), Gaps = 131/762 (17%) Query: 95 PVVVRPYPQVQMLSTHHAVASATPVAVTAPPA-HLTPAVPLSFSEGLMKPPPKPTM---- 149 P V+ +++ A S++P TA PA T P + S + P P ++ Sbjct: 2629 PKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATS---VTPIPSSSLGTTW 2685 Query: 150 -----PSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHI 204 + P A +T S P+ TV ++ + VAT S G Sbjct: 2686 TRLSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVP 2745 Query: 205 MTTNVQMSIIRSNAPG----PPLHIGASHLPR------------GAAAAAVMSSSKVTTV 248 TT + S++PG PP+ I + P G A + ++ TTV Sbjct: 2746 TTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTV 2805 Query: 249 LRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSA--TRAQSPVITTT 306 + P+++T H P+ + T ++PP+ TV T A S ++ TT Sbjct: 2806 ATGSMATPSSSTQTSGTTHT--PPVPNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTT 2863 Query: 307 AAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQK 366 H T+ P+ H +A TT T S PAL +P Sbjct: 2864 --HITE-----PSTVTSHTLAA-------------TTGTTQHSTPALSSPH--------- 2894 Query: 367 TIFSTGTPVAAATVAPILATNTIPSATTAGS-VSHTQAPTSTIVTMTVPSHSSHA--TAV 423 P + T +P T P TTA S + T P+ T + +PS + A T V Sbjct: 2895 -------PSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTV 2947 Query: 424 TTSNIPVAKVVPQQITHTSPRIQPD-YPAERSSLIPISGHRASPNPVAMETRSDNRPSVP 482 T + + ++ P P + S I +G P+ +E R+ +P VP Sbjct: 2948 VTMGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVP 3007 Query: 483 VQ----------------------------FQYFL----------PTYP-------PSAY 497 ++ F Y + P+ P PS+ Sbjct: 3008 LRELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPSST 3067 Query: 498 PLAAHTYTPITSSVSTIRQYPVSAQAPNSAITA--QTGVGVASTVHLNPMQLMTVDASHA 555 P T +T++ +T +A ++ T T +TV + T ++ A Sbjct: 3068 PGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQA 3127 Query: 556 R----HIQGIQPAPISTQGIQPAPIGTPGIQPA-PLGTQGIHSATPINTQGLQPAPMGTQ 610 H+ P T + P +PG A P + T + + + +GT Sbjct: 3128 TAGTPHVSTTATTPTVTSS-KATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTT 3186 Query: 611 QPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSI 670 + T+ AT + P + S T + S +T + G++ + Sbjct: 3187 WTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTAHTTKV 3246 Query: 671 LRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAA 730 L A P S + PV +S T T + P P + T Sbjct: 3247 LTTTTTGFTATPSSSPGTARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTT 3306 Query: 731 ASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLS 772 + S + ST TPP+ A T G SLS Sbjct: 3307 VATGSMATPSSSTQTSGTTHTPPVPNTTA-----TTHGRSLS 3343 Score = 71.6 bits (174), Expect = 4e-12 Identities = 115/527 (21%), Positives = 186/527 (35%), Gaps = 54/527 (10%) Query: 278 PVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQ 337 P T+S A P + T Q+ TTTA + +A+ T PP S Sbjct: 3558 PATSSTATPSSTPGTTWILTEQTTAATTTATTGS-TAIPSSTPGTAPPPKVLTSTATTPT 3616 Query: 338 SRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTA-- 395 + +++ T S P T L + A K+ ++ TP+ + T+ T T+P TT Sbjct: 3617 A--TSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLG---TTGTLPEQTTTPM 3671 Query: 396 ---GSVSHTQAP----TSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPD 448 ++ + P TST++T + + ++ T S+ P + ++T + Sbjct: 3672 ATMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAAT 3731 Query: 449 YPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPIT 508 P S P + E + +VP + +A L T T T Sbjct: 3732 GPTATPSSTP------GTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATT 3785 Query: 509 SSVSTIRQYPVSAQAPNSAITAQTGVGVAST-VHLNPMQLMTVDASHARHIQGIQP-API 566 +V + R P S+ +A+ A T + + ++ + R Q P A + Sbjct: 3786 PTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATM 3845 Query: 567 STQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADG 626 ST TP P + T + + T T+ + P T+ V Sbjct: 3846 ST--------ATPSSTPETVHTSTVLTTTTTTTRATGSVATPSSTP-GTAHTTKVPTTTT 3896 Query: 627 ATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEI 686 A P S+P +A + S +T +GS+ PS + P T + + Sbjct: 3897 TGFTATPSSSPGTALTPPVWI------STTTTPTTRGSTVTPSSI---PGT--THTATVL 3945 Query: 687 HVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQP-------AV 739 + T T SM T S+ T PP P T T + PPS P Sbjct: 3946 TTTTTTVATGSMATPSSSTQTSGTTHTPPV----PNTTATTHGRSLPPSSPHTVRTAWTS 4001 Query: 740 ALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKE 786 A S I G IT P T + P + + + L P P + E Sbjct: 4002 ATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPHPSSRTTE 4048 Score = 70.9 bits (172), Expect = 6e-12 Identities = 95/427 (22%), Positives = 160/427 (37%), Gaps = 65/427 (15%) Query: 243 SKVTTVLRPTSQLPNAAT--AQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS 300 +++TT T + AT + P I+ + P T + +P AT S+T+A + Sbjct: 3075 TELTTTATTTESTGSTATPSSTPGTTWIL-----TEPSTTATVTVPTGSTATASSTQATA 3129 Query: 301 --PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQ 358 P ++TTA T ++ S +A +++ A + T+ +PS +LGT Sbjct: 3130 GTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPS-SSLGTTWT 3188 Query: 359 QLHTMAQKTIFSTGTPVAA-ATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHS 417 +L T TP A +T P T+ ++T + + T T ++ T + + Sbjct: 3189 RLS--------QTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGT 3240 Query: 418 SHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDN 477 +H T V T+ P T+ R P ++ T Sbjct: 3241 AHTTKVLTTTTTGFTATPSSSPGTA--------------------RTLPVWISTTTTPTT 3280 Query: 478 RPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVA 537 R S T PS+ P HT T +T++ +T+ A S T + + Sbjct: 3281 RGS----------TVTPSSIPGTTHTPTVLTTTTTTV--------ATGSMATPSSSTQTS 3322 Query: 538 STVHLNPMQLMTVDASHARHIQGIQPAPIST--QGIQPAPIGTPGIQPAPLGTQGIHSAT 595 T H P+ T +H R + P + T +GT I GT +AT Sbjct: 3323 GTTHTPPVP-NTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAAT 3381 Query: 596 PINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHS--Q 653 TQ PA P P +T+ + G T + + + A A + +T + Sbjct: 3382 TGTTQHSTPA---LSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATATPSKTRTSTLLP 3438 Query: 654 SASTNAP 660 S+ T+AP Sbjct: 3439 SSPTSAP 3445 Score = 70.5 bits (171), Expect = 8e-12 Identities = 156/696 (22%), Positives = 246/696 (35%), Gaps = 92/696 (13%) Query: 108 STHHAVASATPV---AVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSL 164 S+ A+A P T P A A+P S + T P+ ++ A PS S Sbjct: 3796 SSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPS--ST 3853 Query: 165 PPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPG---- 220 P V +T ++ +A+ VAT S G TT + S++PG Sbjct: 3854 PETVHTSTVLTTTTTTTRATG-SVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALT 3912 Query: 221 PPLHIGASHLPR------------GAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHI 268 PP+ I + P G A + ++ TTV + P+++T H Sbjct: 3913 PPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHT 3972 Query: 269 IHQPIQSRPPVTTSNAIPPAVVATVSA--TRAQSPVITTTAAHATDSALSRPTLSIQHPP 326 P+ + T ++PP+ TV T A S ++ TT H T+ P+ H P Sbjct: 3973 --PPVPNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTT--HITE-----PSTVTSHTP 4023 Query: 327 SAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILAT 386 +A TT T S PAL +P T T +P + T P Sbjct: 4024 AA-------------TTSTTQHSTPALSSPHPSSRT--------TESPPSPGTTTPGHTR 4062 Query: 387 NTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA--TAVTTSNIPVAKVVPQQITHTSPR 444 T S TTA T P+ T + +PS + A T V T+ + + ++ P Sbjct: 4063 GT--SRTTA-----TATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPM 4115 Query: 445 IQPDY-PAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHT 503 P + S I +G P+ +E R+ +P VP++ + + L Sbjct: 4116 PGPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLR-ELGQVVECSLDFGLVCRN 4174 Query: 504 YTPITSSVSTIRQYPVSA------QAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARH 557 + Y + P++ T+ T ++ + +T A+ Sbjct: 4175 REQV-GKFKMCFNYEIRVFCCNYGHCPSTPATSSTATPSSTPGTTWILTKLTTTATTTES 4233 Query: 558 IQGIQPAPISTQGI-----QPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAP-MGTQQ 611 G P ST G +P+ T + P G+ +AT +TQ P + T Sbjct: 4234 T-GSTATPSSTPGTTWILTEPSTTATVTV---PTGS----TATASSTQATAGTPHVSTTA 4285 Query: 612 PQPEGKTS-AVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSI 670 P +S A + T A P + P AT+ S S T + P+ Sbjct: 4286 TTPTVTSSKATPFSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTA 4345 Query: 671 LRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPP-PTIPTMIA 729 AT + P++ H S T +T + T + + P TA PT T Sbjct: 4346 TMST-ATPSSTPETA-HTS--TVLTTTATTTRATGSVATPSSTPGTAHTTKVPTTTTTGF 4401 Query: 730 AASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSV 765 +P S P A + T P T+ + P SV Sbjct: 4402 TVTPSSSPGTARTPPVWISTTTTPTTSGSTVTPSSV 4437 Score = 65.1 bits (157), Expect = 3e-10 Identities = 118/536 (22%), Positives = 188/536 (35%), Gaps = 70/536 (13%) Query: 274 QSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQ 333 Q+ TT+ A+ ++ T V+T+TA T ++ S+ T S + + + Sbjct: 3579 QTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATS-SKATSSSSPRTATTLPVL 3637 Query: 334 RPAQSRDVTTRITLPSHPALGT----PKQQLHTMA-QKTIFSTGTPVAAATVAPILATNT 388 ++ T T LGT P+Q MA TI + TP T + +L T Sbjct: 3638 TSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSSTPETTHT-STVLTT-- 3694 Query: 389 IPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITH---TSPRI 445 ATT + S P+ST T + + + A T + P A T T P Sbjct: 3695 --KATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPST 3752 Query: 446 QPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYT 505 S S RA+ + + T + P+V + + + P +A L A T Sbjct: 3753 TATVTVPTGSTATASSTRATAGTLKVLTSTATTPTV-ISSRATPSSSPGTATALPALRST 3811 Query: 506 PITSSVSTIRQYPVSA-----------QAPNSAITAQTGVGVASTVHLNPMQLMTVDASH 554 T + +++ P S+ P + ++ T TVH + + T + Sbjct: 3812 ATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTR 3871 Query: 555 ARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAP----MGTQ 610 A G P ST GT P T +ATP ++ G P T Sbjct: 3872 A---TGSVATPSSTP-------GTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTT 3921 Query: 611 QPQPEGKT-----------SAVVLADGATIVA-NPISNPFSAA---------PAATTVVQ 649 P G T +A VL T VA ++ P S+ P T Sbjct: 3922 TPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTAT 3981 Query: 650 THSQSASTNAP----AQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQN 705 TH +S ++P +S IL T+ + S + + S +S+ + Sbjct: 3982 THGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTPAATTSTTQHSTPALSSPH 4041 Query: 706 NDQPTIAVPPTAQQPPP-----TIPTMIAAASPPSQPAVALSTIPGAVPITPPITT 756 T PP+ P T T A ++ + L + P + PIT +TT Sbjct: 4042 PSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRTSTLLPSSPTSAPITTVVTT 4097 Score = 63.5 bits (153), Expect = 1e-09 Identities = 175/754 (23%), Positives = 251/754 (33%), Gaps = 89/754 (11%) Query: 115 SATPVAVTAPPAHLTPAVPLSF-SEGLMKPPPKP--------TMPSRPIAPAPPS---TL 162 S TP A T H TPA+ S + PP P T SR A A PS T Sbjct: 4522 SHTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTS 4581 Query: 163 SLPPKVPGQV---TVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMS--IIRSN 217 +L P P TV PQ + S PS +N++ + + Sbjct: 4582 TLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPSGGDFDTYSNIRAAGGAVCEQ 4641 Query: 218 APGPPLHIGASH-LPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHII-----HQ 271 G A +P G V S V R Q+ + H Sbjct: 4642 PLGLECRAQAQPGVPLGELGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHC 4701 Query: 272 PIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAIS 331 P P T+S A+P + T + TTTA+ + +A T PP S Sbjct: 4702 P---STPATSSTAMPSSTPGTTWILTELTTTATTTASTGS-TATPSSTPGTAPPPKVLTS 4757 Query: 332 IQRPAQSRDVTT-RITLPSHPALGTPKQQLHTMAQK------------TIFSTGTPVAAA 378 PA + T+ + T S P T L + A K T+ +TGT + Sbjct: 4758 ---PATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGT-LPEQ 4813 Query: 379 TVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQI 438 T P+ +TI ++T + TST++T + + ++ T S+ P + ++ Sbjct: 4814 TTTPVATMSTIHPSSTPETTH-----TSTVLTTKATTTRATSSTSTPSSTPGTTWILTEL 4868 Query: 439 THTSPRIQPDYPAERSSLIP----ISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPP 494 T + P S P I + T S PS + L Sbjct: 4869 TTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWIL----- 4923 Query: 495 SAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASH 554 P T T T S +T +A P+ + TA T V S+ T A Sbjct: 4924 -TEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPT-VTSSKATPSSSPGTATALP 4981 Query: 555 ARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQP 614 A P S I + +GT T+ + TP T + Sbjct: 4982 ALRSTATTPTATSFTAIPSSSLGT-------TWTRLSQTTTPTATMSTATPSSTPETVHT 5034 Query: 615 EGKTSAVVLADGAT-IVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRK 673 +A GAT VA P S P A TT V T + + T P S P Sbjct: 5035 STVLTATATTTGATGSVATPSSTP---GTAHTTKVPTTTTTGFTATP----SSSPGTALT 5087 Query: 674 KPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIP-------- 725 P T S IH S +TP T TV T A TA P T+ Sbjct: 5088 PPTTTPMSTMSTIHTS-STPETTHTSTVLTTTATM-TRATNSTA-TPSSTLGTTRILTEL 5144 Query: 726 TMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVK 785 T A + + LS+ PG I +TIA P+ + + S++ P++ Sbjct: 5145 TTTATTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTT 5204 Query: 786 EEVEPMDIMRPVSAVPPLATNTVSPSLALLANNL 819 P S VP +T + + A+L ++L Sbjct: 5205 MATMP---TATASTVPSSSTVGTTRTPAVLPSSL 5235 Score = 62.0 bits (149), Expect = 3e-09 Identities = 126/546 (23%), Positives = 180/546 (32%), Gaps = 94/546 (17%) Query: 39 STGLSQAPSQIANSGSAG--LINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPV 96 STG + PS + L +PA T S + + S+ ++ L S K Sbjct: 4735 STGSTATPSSTPGTAPPPKVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTAT 4794 Query: 97 VVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAP 156 V P P + +T P T P A ++ P S E T + A Sbjct: 4795 SVTPIPSSTLGTT-----GTLPEQTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRAT 4849 Query: 157 APPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRS 216 + ST S P +T ++ A+ P AT S G L + TT + S Sbjct: 4850 SSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTELTTTATTTASTGS 4909 Query: 217 NA-----PGP------PLHIGASHLPRGAAAAAVMSSSKV------TTVLRPT------- 252 A PG P +P G+ A A + + TT PT Sbjct: 4910 TATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKAT 4969 Query: 253 -SQLPNAATAQPAVQHIIHQPIQSR---------------------PPVTTSNAIPPAVV 290 S P ATA PA++ P + P T S A P + Sbjct: 4970 PSSSPGTATALPALRSTATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTP 5029 Query: 291 ATVSATRAQSPVITTTAA--------------HATDSALSRPTLSIQHPPSAAISIQRPA 336 TV + + TTT A H T + T P S+ + P Sbjct: 5030 ETVHTSTVLTATATTTGATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPP 5089 Query: 337 QSRDVTTRITL-----PSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPS 391 + ++T T+ P T TM + T ST TP + IL T + Sbjct: 5090 TTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATN-STATPSSTLGTTRILTELTTTA 5148 Query: 392 ATTAGS-----VSHTQAPT------STIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITH 440 TTA + +S T T STI T+ VP+ S+ + T KVV T Sbjct: 5149 TTTAATGSTATLSSTPGTTWILTEPSTIATVMVPTGSTATASSTLGTAHTPKVVTTMAT- 5207 Query: 441 TSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLA 500 P +S +P S + A+ S SV L T P+ +P + Sbjct: 5208 --------MPTATASTVPSSSTVGTTRTPAVLPSSLPTFSVSTVSSSVLTTLRPTGFP-S 5258 Query: 501 AHTYTP 506 +H TP Sbjct: 5259 SHFSTP 5264 Score = 60.1 bits (144), Expect = 1e-08 Identities = 145/639 (22%), Positives = 212/639 (33%), Gaps = 82/639 (12%) Query: 243 SKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIP---PAVVATVSATRAQ 299 S TV PT A++ Q + P VT+S A P P + A R+ Sbjct: 4254 STTATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRST 4313 Query: 300 SPVITTTAAHATDSALSRPT---LSIQHPPSAAISIQRPAQSRDV--------TTRITLP 348 + T T+ A S+ T LS P+A +S P+ + + TT T Sbjct: 4314 ATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTR 4373 Query: 349 SHPALGTPKQQ---LHTMAQKTIFSTG-------TPVAAATVAPILATNTIPSATTAGSV 398 + ++ TP HT T +TG +P A T ++T T P TT+GS Sbjct: 4374 ATGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTP--TTSGST 4431 Query: 399 SHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIP 458 + T T TV + ++ A + P + THT P SL P Sbjct: 4432 VTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSP 4491 Query: 459 ISGHR-----ASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVST 513 S H S + T PS ++ P+A TP SS Sbjct: 4492 SSPHTVRTAWTSATSGTLGTTHITEPSTGT-------SHTPAATTGTTQHSTPALSSPHP 4544 Query: 514 IRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPIS---TQG 570 + S +P + T +T P + T + API+ T G Sbjct: 4545 SSRTTESPPSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTS----APITTVVTTG 4600 Query: 571 IQPAPIGTPGIQ---PAPLGTQGIHSATPINTQGLQPA----PMG------TQQPQPEGK 617 +P + + P P G G T N + A P+G Q P G+ Sbjct: 4601 CEPQCAWSEWLDYSYPMP-GPSGGDFDTYSNIRAAGGAVCEQPLGLECRAQAQPGVPLGE 4659 Query: 618 TSAVV---LADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKK 674 VV L G F V + + PA S+ PS Sbjct: 4660 LGQVVECSLDFGLVCRNREQVGKFKMCFNYEIRVFCCNYGHCPSTPATSSTAMPS---ST 4716 Query: 675 PATDGAKPKSEIHVSMATPVTVSMETVSNQN-NDQPTIAVPPTAQQPPPTIPTMIAAASP 733 P T + I + T T + T S + P A PP P T PT ++ + Sbjct: 4717 PGT------TWILTELTTTATTTASTGSTATPSSTPGTAPPPKVLTSPATTPTATSSKAT 4770 Query: 734 PSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDI 793 S +T+P T + P PS T+G + +PE + V M Sbjct: 4771 SSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTT------GTLPE-QTTTPVATMST 4823 Query: 794 MRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASP 832 + P S T+TV L A +S P ++P Sbjct: 4824 IHPSSTPETTHTSTV---LTTKATTTRATSSTSTPSSTP 4859 Score = 57.0 bits (136), Expect = 9e-08 Identities = 106/455 (23%), Positives = 155/455 (34%), Gaps = 66/455 (14%) Query: 361 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA 420 H + ST TP + IL T +ATT + T P+ST T P Sbjct: 3553 HCPSTPATSSTATPSSTPGTTWILTEQTT-AATTTATTGSTAIPSSTPGTAPPPK----- 3606 Query: 421 TAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPS 480 +T+ P A + + +SPR P S+ + +P P + P Sbjct: 3607 VLTSTATTPTA-TSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPE 3665 Query: 481 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTV 540 + T PS+ P HT T +T+ +T R S+ + S+ T + T Sbjct: 3666 QTTTPMATMSTIHPSSTPETTHTSTVLTTKATTTRA--TSSMSTPSSTPGTTWILTELTT 3723 Query: 541 HLNPMQLMTVDASHARHIQGIQPAPISTQGI-----QPAPIGTPGIQPAPLGTQGIHSAT 595 A+ G P ST G +P+ T + P G+ S+T Sbjct: 3724 -----------AATTTAATGPTATPSSTPGTTWILTEPSTTATVTV---PTGSTATASST 3769 Query: 596 PINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSA 655 T G T + A + T A P + P AT+V S S Sbjct: 3770 RA-TAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSL 3828 Query: 656 STNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPP 715 T + P+ AT + P++ +H S T +T + T + + P Sbjct: 3829 GTAWTRLSQTTTPTATMST-ATPSSTPET-VHTS--TVLTTTTTTTRATGSVATPSSTPG 3884 Query: 716 TAQQPP-PTIPTMIAAASPPSQPAVAL---------------------STIPG----AVP 749 TA PT T A+P S P AL S+IPG A Sbjct: 3885 TAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTPSSIPGTTHTATV 3944 Query: 750 ITPPITTIA----AAPPPSVTVGGSLSSVLGPPVP 780 +T TT+A A P S G+ + PPVP Sbjct: 3945 LTTTTTTVATGSMATPSSSTQTSGTTHT---PPVP 3976 Score = 56.2 bits (134), Expect = 2e-07 Identities = 101/438 (23%), Positives = 153/438 (34%), Gaps = 80/438 (18%) Query: 361 HTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPT------------STI 408 H + ST TP + IL T +ATT S T P+ ST Sbjct: 4198 HCPSTPATSSTATPSSTPGTTWIL-TKLTTTATTTESTGSTATPSSTPGTTWILTEPSTT 4256 Query: 409 VTMTVPSHSSH--------------ATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERS 454 T+TVP+ S+ +T TT + +K P +SP PA RS Sbjct: 4257 ATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATP----FSSPGTATALPALRS 4312 Query: 455 SLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTI 514 + + + P + + R S + T PS+ P AHT T +T++ +T Sbjct: 4313 TATTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTT 4372 Query: 515 RQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPA 574 R A S T + G A T + +T G Sbjct: 4373 R-------ATGSVATPSSTPGTAHTTKV---------------------PTTTTTGFTVT 4404 Query: 575 PIGTPGIQPAPLGTQGIHSATPINTQGLQPAPM---GTQQPQPEGKTSAVVLADGATIVA 631 P +PG P I + T T G P GT T+ +A G+ +A Sbjct: 4405 PSSSPGTARTP--PVWISTTTTPTTSGSTVTPSSVPGTTHTPTVLTTTTTTVATGS--MA 4460 Query: 632 NPISNPFSAA-----PAATTVVQTHSQSASTNAP----AQGSSPRPSILRKKPATDGAKP 682 P S+ ++ P T TH +S S ++P +S L T+ + Sbjct: 4461 TPSSSTQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTG 4520 Query: 683 KSEIHVSMATPVTVSMET--VSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPA-V 739 S H AT T T +S+ + T PP+ P T + + + P+ Sbjct: 4521 TS--HTPAATTGTTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTTATSRTTATATPSKT 4578 Query: 740 ALSTIPGAVPITPPITTI 757 ST+ + P + PITT+ Sbjct: 4579 RTSTLLPSSPTSAPITTV 4596 Score = 55.5 bits (132), Expect = 3e-07 Identities = 116/530 (21%), Positives = 172/530 (32%), Gaps = 58/530 (10%) Query: 39 STGLSQAPSQIANSGSAG--LINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPV 96 +TG + PS + L + A T S + + S+ ++ L S K Sbjct: 3588 TTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSKATSSSSPRTATTLPVLTSTATKSTAT 3647 Query: 97 VVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAP 156 P P + +T P T P A ++ P S E + ++ Sbjct: 3648 SFTPIPSFTLGTT-----GTLPEQTTTPMATMSTIHPSSTPE---TTHTSTVLTTKATTT 3699 Query: 157 APPSTLSLPPKVPGQVTVTME---SSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSI 213 S++S P PG + E ++ A+ P AT S G L TT Sbjct: 3700 RATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTPGTTWILTEPSTTATVTVP 3759 Query: 214 IRSNAPGPPLHIGASHLP--RGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQ 271 S A A L A + SS+ T S P ATA PA++ Sbjct: 3760 TGSTATASSTRATAGTLKVLTSTATTPTVISSRATP-----SSSPGTATALPALRSTA-- 3812 Query: 272 PIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAIS 331 + P T+ AIP + + T +Q+ T T + AT S+ + Sbjct: 3813 ---TTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPE-----------TVH 3858 Query: 332 IQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTG-------TPVAAATVAPIL 384 + TTR T TP HT T +TG +P A T + Sbjct: 3859 TSTVLTTTTTTTRATGSVATPSSTPGTA-HTTKVPTTTTTGFTATPSSSPGTALTPPVWI 3917 Query: 385 ATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPR 444 +T T P TT GS + T T TV + ++ A + P + THT P Sbjct: 3918 STTTTP--TTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPV 3975 Query: 445 IQPDYPAERSSLIPISGHR-----ASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPL 499 SL P S H S + T PS + ++ P+A Sbjct: 3976 PNTTATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPST-------VTSHTPAATTS 4028 Query: 500 AAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMT 549 TP SS + S +P + T +T P + T Sbjct: 4029 TTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATATPSKTRT 4078 Score = 53.5 bits (127), Expect = 1e-06 Identities = 143/589 (24%), Positives = 198/589 (33%), Gaps = 123/589 (20%) Query: 251 PTSQLPNAATAQPAVQHIIHQPIQS----RPPVTTSNAIPPAVVATVSATRAQSPVITTT 306 PT++L A T QP S R P ++ A+P S + TT Sbjct: 2305 PTTELETATTTTTQALFSTPQPTSSPGLTRAPPASTTAVPTLSEGLTSPRYTSTLGTATT 2364 Query: 307 AAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHP-ALGTPK-QQLHTMA 364 T + + PT+ P A S + TR LP +LGT + Q T+A Sbjct: 2365 GGPTTPAGSTEPTV-----PGVATST--------LPTRSALPGTTGSLGTWRPSQPPTLA 2411 Query: 365 QKTIF-STGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAV 423 T+ S P A+ A T + T +S +QA TST T T S T Sbjct: 2412 PTTMATSRARPTGTASTASKEPLTTSLAPTLTSELSTSQAETSTPRTETT---MSPLTNT 2468 Query: 424 TTSNIPVAKVVPQQITHTSPRIQ------PDYPA--------ERSSLIPISGHRASPNPV 469 TTS Q T P+ + D+P E I +G + P Sbjct: 2469 TTS---------QGTTRCQPKCEWTEWFDVDFPTSGVAGGDMETFENIRAAGGKMCWAPK 2519 Query: 470 AMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAIT 529 ++E R++N P V + +T S+ T N T Sbjct: 2520 SIECRAENYPEVSID-----------------QVGQVLTCSLET------GLTCKNEDQT 2556 Query: 530 AQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQ 589 + + + N L D SH PA ST P GT I P T Sbjct: 2557 GRFNM----CFNYNVRVLCCDDYSHCPST----PATSSTATPSSTP-GTTWILTKPTTTA 2607 Query: 590 GI-----HSATPINTQGLQPAP--MGTQQPQPEGKTS-AVVLADGATIVANPISNPFSAA 641 +ATP +T P P + T P +S A + T A P + Sbjct: 2608 TTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATT 2667 Query: 642 PAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETV 701 P AT+V S S T + P+ AT + P++ H S T +T + T Sbjct: 2668 PTATSVTPIPSSSLGTTWTRLSQTTTPTATMST-ATPSSTPETA-HTS--TVLTATATTT 2723 Query: 702 SNQNNDQPTIAVPPTAQQPP-PTIPTMIAAASPPSQPAVAL------------------- 741 + + P TA PT T A+P S P AL Sbjct: 2724 GATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTV 2783 Query: 742 --STIPG----AVPITPPITTIA----AAPPPSVTVGGSLSSVLGPPVP 780 S+IPG A +T TT+A A P S G+ + PPVP Sbjct: 2784 TPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHT---PPVP 2829 Score = 47.4 bits (111), Expect = 7e-05 Identities = 100/436 (22%), Positives = 153/436 (35%), Gaps = 92/436 (21%) Query: 373 TPVAAATVAPI-------LATNTIPSATTAGSVSHTQAPT------------STIVTMTV 413 TP ++T P + T +ATT S T P+ ST T+TV Sbjct: 3055 TPATSSTAMPSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTV 3114 Query: 414 PSHSSH--------------ATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPI 459 P+ S+ +T TT + +K P +SP PA RS+ Sbjct: 3115 PTGSTATASSTQATAGTPHVSTTATTPTVTSSKATP----FSSPGTATALPALRSTATTP 3170 Query: 460 SGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPV 519 + + P + + R S + T PS+ P HT T +T++ +T Sbjct: 3171 TATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATT------ 3224 Query: 520 SAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTP 579 A S T + G A T +++T +T G P +P Sbjct: 3225 -TGATGSVATPSSTPGTAHTT-----KVLTT----------------TTTGFTATPSSSP 3262 Query: 580 GIQPAPLGTQGIHSATPINTQGLQPAPM---GTQQPQPEGKTSAVVLADGATIVANPISN 636 G A I + T T+G P GT T+ +A G+ +A P S+ Sbjct: 3263 G--TARTLPVWISTTTTPTTRGSTVTPSSIPGTTHTPTVLTTTTTTVATGS--MATPSSS 3318 Query: 637 PFSAA-----PAATTVVQTHSQSASTNAP----AQGSSPRPSILRKKPATDGAKPKSEIH 687 ++ P T TH +S S ++P +S L T+ + S H Sbjct: 3319 TQTSGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTS--H 3376 Query: 688 VSMATPVTVSMET--VSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPA----VAL 741 AT T T +S+ + T PP+ P T P A S + A Sbjct: 3377 TPAATTGTTQHSTPALSSPHPSSRTTESPPS---PGTTTPGHTRATSRTTATATPSKTRT 3433 Query: 742 STIPGAVPITPPITTI 757 ST+ + P + PITT+ Sbjct: 3434 STLLPSSPTSAPITTV 3449 Score = 32.0 bits (71), Expect = 3.1 Identities = 46/202 (22%), Positives = 78/202 (38%), Gaps = 24/202 (11%) Query: 639 SAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSM 698 + P TT ++T + +T A S+P+P+ P A P S T ++ Sbjct: 2300 ATTPPPTTELET---ATTTTTQALFSTPQPT---SSPGLTRAPPAS----------TTAV 2343 Query: 699 ETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP--GAVP-ITPPIT 755 T+S + TA PT P A ++ P+ P VA ST+P A+P T + Sbjct: 2344 PTLSEGLTSPRYTSTLGTATTGGPTTP---AGSTEPTVPGVATSTLPTRSALPGTTGSLG 2400 Query: 756 TIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALL 815 T + PP++ +S P + EP+ + L+T+ S Sbjct: 2401 TWRPSQPPTLAPTTMATSRARPTGTASTASK--EPLTTSLAPTLTSELSTSQAETSTPRT 2458 Query: 816 ANNLSMPTSDLPPGASPRKKPR 837 +S T+ + R +P+ Sbjct: 2459 ETTMSPLTNTTTSQGTTRCQPK 2480 Score = 32.0 bits (71), Expect = 3.1 Identities = 33/151 (21%), Positives = 52/151 (34%), Gaps = 12/151 (7%) Query: 690 MATPVTVSMETVSNQNNDQPT----IAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIP 745 + P T + T S + PT A PP T PT+ ++ + PS + +P Sbjct: 2600 LTKPTTTATTTASTGSTATPTSTLRTAPPPKVLTTTATTPTVTSSKATPSSSPGTATALP 2659 Query: 746 GAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLAT 805 T + P PS ++G + + + P M P S T Sbjct: 2660 ALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTP-------TATMSTATPSSTPETAHT 2712 Query: 806 NTVSPSLALLANNL-SMPTSDLPPGASPRKK 835 +TV + A S+ T PG + K Sbjct: 2713 STVLTATATTTGATGSVATPSSTPGTAHTTK 2743 >gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo sapiens] Length = 1560 Score = 77.0 bits (188), Expect = 8e-14 Identities = 168/757 (22%), Positives = 252/757 (33%), Gaps = 192/757 (25%) Query: 115 SATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPK--VPGQV 172 S P+AV AP +P VP ++ P P P +P PP L PK P Sbjct: 321 SGQPLAV-APGLGSSPLVPAP--NVILHRTPTPIQP-KPAGVLPPKLYQLTPKPFAPAGA 376 Query: 173 TVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPR 232 T+T++ + A+P Q P NL + +++ S P P L Sbjct: 377 TLTIQG---EPGALPQ-----QPKAPQNLTFMAAGKAGQNVVLSGFPAPALQAN------ 422 Query: 233 GAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVAT 292 + +PP TT+ A PP Sbjct: 423 ----------------------------------------VFKQPPATTTGAAPP----- 437 Query: 293 VSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSR-DVTTRITLPSHP 351 Q P ALS+P +S+ H + SI PAQ + LP P Sbjct: 438 ------QPP-----------GALSKP-MSV-HLLNQGSSIVIPAQHMLPGQNQFLLPGAP 478 Query: 352 ALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTM 411 A+ P QQL + A T ++A + + AG +S ++ Sbjct: 479 AVQLP-QQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLS-----LGPVLAP 532 Query: 412 TVPSHSSHATAVTTSNI--PVAKVVPQQITHTS-PRIQPDYPAERSSLIPISGHRASPNP 468 +HS+H + + P +P + S P PA ++ + G P+ Sbjct: 533 HSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSA 592 Query: 469 VAMETRSDN--RPSVPV----QFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVS-- 520 VAM D +P+ P + L P P A T P+ +Q P + Sbjct: 593 VAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPT 652 Query: 521 --AQAPNSAITAQTGVGVASTVH---------LNPMQLMTVDASHARHIQGIQPAPISTQ 569 A AP A T Q G+AS+ P ++T D+ +Q P S Q Sbjct: 653 PQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDS-----LQMFLPQERSQQ 707 Query: 570 GIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATI 629 PL +G H + P + + AP Q P P A +A GA + Sbjct: 708 ---------------PLSAEGPHLSVPASV--IVSAPPPAQDPAP-----ATPVAKGAGL 745 Query: 630 VANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVS 689 + S APA A+ G S PS+ + P Sbjct: 746 GPQAPDSQASPAPAPQI-------PAAAPLKGPGPSSSPSLPHQAPL------------- 785 Query: 690 MATPVTVSMETVSNQNNDQPTIAVPPTAQQP--PPTIPTMIAAASPPSQPAVALSTIPGA 747 D P + P + P PP+ P ++ PPS+P + P A Sbjct: 786 ----------------GDSPHLPSPHPTRPPSRPPSRPQSVSR--PPSEPPLHPCPPPQA 827 Query: 748 VPITPPITTI---AAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLA 804 P P I I PPP+ + GPP P ++ + + P + P +PP + Sbjct: 828 PPTLPGIFVIQNQLGVPPPA---SNPAPTAPGPPQPPLRPQSQ-PPEGPLPPAPHLPPSS 883 Query: 805 TNTVSPSLALLANNLSMPTS-----DLPPGASPRKKP 836 T++ S + ++ L PT PP P K P Sbjct: 884 TSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSP 920 Score = 61.2 bits (147), Expect = 5e-09 Identities = 170/825 (20%), Positives = 289/825 (35%), Gaps = 144/825 (17%) Query: 104 VQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKP-PPKPTMPSRPIAPAPPSTL 162 VQ + A A PV P PAV GL +P +P P A APP Sbjct: 603 VQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQA- 661 Query: 163 SLPPKVPGQVTVTMESSIPQ-ASAIPVATIS------------GQQGHPSNLHHIMTTNV 209 + P PG + + + Q SA P A ++ QQ + H+ +V Sbjct: 662 TTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHL---SV 718 Query: 210 QMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAA-------TAQ 262 S+I S P A+ + +GA S+ + P Q+P AA ++ Sbjct: 719 PASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPA--PAPQIPAAAPLKGPGPSSS 776 Query: 263 PAVQH---IIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPT 319 P++ H + P P T + PP+ +VS ++ P+ H + PT Sbjct: 777 PSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPL------HPCPPPQAPPT 830 Query: 320 LSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAAT 379 L + + PA + P+ A G P+ L +Q P Sbjct: 831 LPGIFVIQNQLGVPPPASN---------PAPTAPGPPQPPLRPQSQ-------PPEGPLP 874 Query: 380 VAPILATNTIPSATTAGS--VSHTQAPTSTIVTMTVP----SHSSHATAVTTSNIPVAKV 433 AP L ++ SA + S S APT + + P H S T +P Sbjct: 875 PAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAA 934 Query: 434 VP-------QQITHTSPRI-QPDYPAERSSLIP---ISGHRASPNPVAMETRSDNRP--- 479 P Q +T P + QP ER +P I ++A P A +T + P Sbjct: 935 PPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTS 994 Query: 480 ---SVPVQFQY-----FLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQ 531 SV V Q P++ P+ P+AA P+ + + + + + N A A Sbjct: 995 PAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAEN--KAFASNLPTLNVAKAAS 1052 Query: 532 TGVGVASTVHLN---------PMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQ 582 +G G S + P + +A H+ Q + + P + Sbjct: 1053 SGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVLH-----------PDYK 1101 Query: 583 PA-PLGTQGIHSATPINT-QGLQPAPMGTQQPQPEGKTSAVVLADGATIVANP-----IS 635 A P +H P + QG P+P + E +T + L + N + Sbjct: 1102 TAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVSTQLLKRTQAMLNKYRLLLLE 1161 Query: 636 NPFSAAPAATTVV--QTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATP 693 +P+A V+ + Q T + ++KP + + S+ P Sbjct: 1162 ESRRVSPSAEMVMIDRMFIQEEKTTLALD-----KQLAKEKPDEYVSSSR-----SLGLP 1211 Query: 694 VTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPP 753 + S E + + + P + QPPP +PT + + + +++ + ++ Sbjct: 1212 IAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSS 1271 Query: 754 ITTIAAAPPPSVTVGGSLSSVLGPPVP----------EIKVKEEVEPMDIMRPVSAVPPL 803 ++ +AA G + S PP+ ++K+K+E ++ +A+ P+ Sbjct: 1272 SSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHN-TALDPV 1330 Query: 804 ATNTVSPSLALLANNLSMP------------TSDLPPGASPRKKP 836 P+ +A P T D PP A+P +KP Sbjct: 1331 HQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKP 1375 Score = 56.6 bits (135), Expect = 1e-07 Identities = 138/622 (22%), Positives = 205/622 (32%), Gaps = 116/622 (18%) Query: 140 LMKPPPKPTMPSRPIAPAPPSTLSLPPKV-----------------PGQVTVTMESS--- 179 + K PP T + P P PP LS P V PGQ + + Sbjct: 423 VFKQPPATTTGAAP--PQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAV 480 Query: 180 -IPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPR-GAAAA 237 +PQ + A + GQ + H + N GP L +G P GA +A Sbjct: 481 QLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGP-LSLGPVLAPHSGAHSA 539 Query: 238 AVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTT---SNAIPPAVVATVS 294 ++S++ + Q+P + A QP + P TT +PP+ VA ++ Sbjct: 540 HILSAAPIQVGQPALFQMPVSLAAGSLPTQ--SQPAPAGPAATTVLQGVTLPPSAVAMLN 597 Query: 295 -------------ATRAQSPVITTTAAHATDSALSRPT-LSIQHPPSAAISIQRPAQSRD 340 AT +PV+T A A+S P L +Q P + Q+P Q+ Sbjct: 598 TPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQA-----QQPPQAP- 651 Query: 341 VTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNT---IPSATTAGS 397 T + P P L + +K + G P +A A + + +P + Sbjct: 652 -TPQAAAPPQATTPQPSPGLASSPEKIVL--GQPPSATPTAILTQDSLQMFLPQERSQQP 708 Query: 398 VS----HTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPA-- 451 +S H P S IV+ P+ + P + SP P PA Sbjct: 709 LSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPD--SQASPAPAPQIPAAA 766 Query: 452 -------ERSSLIPI------SGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYP 498 S +P S H SP+P +R +RP + P P +P Sbjct: 767 PLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSR-----PPSEPPLHP 821 Query: 499 LAAHTYTPITSSVSTIR-QYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARH 557 P + I+ Q V A N A TA P + A H Sbjct: 822 CPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPP 881 Query: 558 IQGIQPAPISTQGIQPAPIGTPG---IQPAPLGTQGIH-SATPINTQGLQPAPMGTQQPQ 613 S++ P TP +Q P +QG H S TP T L P P P Sbjct: 882 SSTSSAVASSSETSSRLPAPTPSDFQLQFPP--SQGPHKSPTPPPTLHLVPEPAAPPPPP 939 Query: 614 PEG-----------------------KTSAVVLAD--GATIVANPISNPFS--AAPAATT 646 P S ++L + G A S +PAA+ Sbjct: 940 PRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASV 999 Query: 647 VVQTHSQSASTNAPAQGSSPRP 668 +V + S + AP+ +P P Sbjct: 1000 LVSGQAPSGTPTAPSHAPAPAP 1021 >gi|149773456 hypothetical protein LOC643314 [Homo sapiens] Length = 1427 Score = 74.3 bits (181), Expect = 6e-13 Identities = 123/537 (22%), Positives = 195/537 (36%), Gaps = 92/537 (17%) Query: 237 AAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVAT-VSA 295 AA +S+ + TV T +P A AV P T+ A+ A+ +SA Sbjct: 898 AAAVSAPERATVPAVTVSVPEGTAAVAAVSS----------PEETAPAVAAAITQEGMSA 947 Query: 296 TRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGT 355 SP AA A ++ + + P + A ++ P + R++ P PA + Sbjct: 948 VAGFSP---EWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPA--S 1002 Query: 356 PKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATT-AGSVSHTQAPTSTIVTMTVP 414 P + T + T + P +P A T+ A +V + PTS + P Sbjct: 1003 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTP 1062 Query: 415 SH-SSHATAVTTSNIPV--AKVVPQQITHTSPRIQ---PDYPAERSSLIPISGHRASPNP 468 +S A AV T P A VP TSP P+ P ++ +P ASP Sbjct: 1063 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASP-A 1121 Query: 469 VAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAI 528 A+ T P P +PT A+P A ++S + P + +P +A+ Sbjct: 1122 AAVPT-----PEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAV 1176 Query: 529 TAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGT 588 P + + A A + PA A + TP A L Sbjct: 1177 PT-------------PAESASFAAVVATLEEPTSPA---------ASVPTPAAMVATLEE 1214 Query: 589 QGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVV 648 +A+ ++ +PA + PE TS + P S+A A T Sbjct: 1215 FTSPAASVPTSE--EPASLAAAVSNPEEPTSPAAAVP-------TLEEPTSSAAAVLTPE 1265 Query: 649 QTHSQSASTNAPAQGSSPRPSILR-KKPATDGAKPKSEIHVSMATPVTVSMETVSNQNND 707 + S +AS P + +SP ++ ++PA+ A A P Sbjct: 1266 ELSSPAASVPTPEEPASPAAAVSNLEEPASPAA----------AVPT------------- 1302 Query: 708 QPTIAVPPTAQQPPPTIPTMIAAASPPSQ-------PAVALSTIPGAVPITPPITTI 757 P +A P A P P +P + AAA PP + P + +S +VPI+ T + Sbjct: 1303 -PEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPV 1358 Score = 63.2 bits (152), Expect = 1e-09 Identities = 144/633 (22%), Positives = 215/633 (33%), Gaps = 119/633 (18%) Query: 251 PTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSP--------V 302 P Q P+ A P V+ + + S T+ A+P V A P + Sbjct: 829 PVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASI 888 Query: 303 ITTTAAHATDSALSRP--------TLSIQHPPSAAISIQRPAQSRD-VTTRITLPSHPAL 353 ++ T +A+S P T+S+ +A ++ P ++ V IT A+ Sbjct: 889 VSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAV 948 Query: 354 G--TPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTM 411 +P+ + GTP T A + P T A VS + P S + Sbjct: 949 AGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPD-TAAVRVSTPEEPASPAAAV 1007 Query: 412 TVPSH-SSHATAVTTSNIPV--AKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNP 468 P +S A AV T P A VP TSP P E P S A P P Sbjct: 1008 PTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEE-----PTSPAAAVPTP 1062 Query: 469 VAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAI 528 E + +VP + PT P +A P +P ++V T P +P +A+ Sbjct: 1063 ---EEPTSPAAAVPTPEE---PTSPAAAVPTPEEPTSP-AAAVPT----PEEPTSPAAAV 1111 Query: 529 TAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGT 588 P P P P P Sbjct: 1112 ----------------------------------PTP-------EEPASPAAAVPTPEEP 1130 Query: 589 QGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAAT--T 646 +A P + PAP P PE SA V A+P + + A +A+ Sbjct: 1131 ASPAAAVPTPEEPAFPAPA---VPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAA 1187 Query: 647 VVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVT---------VS 697 VV T + S A + + L + + + P SE S+A V+ + Sbjct: 1188 VVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAA 1247 Query: 698 METVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASP---------PSQPAVALST----- 743 + T+ + + P P ++PT ASP P+ PA A+ T Sbjct: 1248 VPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAA 1307 Query: 744 IPGAVPITPPITTI-AAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPP 802 IP A TP + I AAA PP V S +G VP + V + + I + V Sbjct: 1308 IPAASVPTPEVPAIPAAAVPPMEEV-----SPIG--VPFLGVSAHTDSVPISEEGTPVLE 1360 Query: 803 LATNT---VSPSLALLANNLSMPTSDLPPGASP 832 A++T + L L + TS + G P Sbjct: 1361 EASSTGMWIKEDLDSLVFGIKEVTSTVLHGKVP 1393 Score = 55.5 bits (132), Expect = 3e-07 Identities = 83/358 (23%), Positives = 126/358 (35%), Gaps = 50/358 (13%) Query: 59 NPAATVNDESGRDSEVSA----REHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVA 114 +PAA V S +A E S ++++ + EE P P P+ T A A Sbjct: 1028 SPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP---TSPAAA 1084 Query: 115 SATPVAVTAPPAHL-TPAVPLSFSEGLMKP--PPKPTM----PSRPIAPAPPSTLSLPPK 167 TP T+P A + TP P S + + P P P P P +PA P Sbjct: 1085 VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPA 1144 Query: 168 VPGQVTVTMESSIPQASAIPV--ATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHI 225 P T E S A A+P + S P+ V ++ +P Sbjct: 1145 FPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSP------ 1198 Query: 226 GASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAI 285 A+ +P AA A + PTS+ P + A S P TS Sbjct: 1199 -AASVPTPAAMVATLEEFTSPAASVPTSEEPASLAA-----------AVSNPEEPTS--- 1243 Query: 286 PPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRI 345 P A V T+ + P ++ AA T LS P S+ P + PA + + Sbjct: 1244 PAAAVPTL-----EEPT-SSAAAVLTPEELSSPAASVPTP-------EEPASPAAAVSNL 1290 Query: 346 TLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQA 403 P+ PA P ++ + ++ + P A P + + G +HT + Sbjct: 1291 EEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDS 1348 Score = 55.1 bits (131), Expect = 3e-07 Identities = 111/525 (21%), Positives = 176/525 (33%), Gaps = 89/525 (16%) Query: 61 AATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVAS---AT 117 AA + D+ + + E +S +++ + E + P+P +L T Sbjct: 838 AAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEEEDVT 897 Query: 118 PVAVTAPPAHLTPAVPLSFSEGLMK----PPPKPTMPS----------RPIAPAPPSTLS 163 AV+AP PAV +S EG P+ T P+ +A P + Sbjct: 898 AAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAA 957 Query: 164 LPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRS-----NA 218 L VP +T E P+ P T+ + + + T S + Sbjct: 958 LAITVP----ITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEP 1013 Query: 219 PGPPLHIGASHLPRGAAAAA------VMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQP 272 P + P AAA ++ V T PTS P AA P Sbjct: 1014 TSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTS--PAAAVPTP--------- 1062 Query: 273 IQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHA-------TDSALSRPTLSIQHP 325 P + + A+P T A +P T+ A A T A + PT + P Sbjct: 1063 ---EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT--PEEP 1117 Query: 326 PSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILA 385 S A ++ P + + P PA P + + TP +A+ A + Sbjct: 1118 ASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVP 1177 Query: 386 TNTIPSATTAGSVSHTQAPTSTIVTMTVPS--------HSSHATAVTTSNIP--VAKVVP 435 T SA+ A V+ + PTS ++ P+ +S A +V TS P +A V Sbjct: 1178 T-PAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVS 1236 Query: 436 QQITHTSPR----------------IQPDYPAERSSLIPISGHRASPNPVAMETRSDNRP 479 TSP + P+ + ++ +P ASP P Sbjct: 1237 NPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASP 1296 Query: 480 SVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAP 524 + V PT +A P AA TP ++ P+ +P Sbjct: 1297 AAAV------PTPEVAAIP-AASVPTPEVPAIPAAAVPPMEEVSP 1334 Score = 49.7 bits (117), Expect = 1e-05 Identities = 82/330 (24%), Positives = 119/330 (36%), Gaps = 47/330 (14%) Query: 573 PAPIGTPGIQP-APLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVA 631 PAP GT + P + I A+ ++ + P+ + V T Sbjct: 864 PAPEGTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAV 923 Query: 632 NPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILR-KKPAT--DGAK-----PK 683 +S+P APA + SA G SP + L P T DG P Sbjct: 924 AAVSSPEETAPAVAAAITQEGMSA-----VAGFSPEWAALAITVPITEEDGTPEGPVTPA 978 Query: 684 SEIHVSMATPVTVSMETVSNQNNDQPTIAVP-------PTAQQPPPTIPTMIAAASPPSQ 736 + +H P T ++ + + P AVP P A P P PT AAA PP + Sbjct: 979 TTVHAP-EEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPE 1037 Query: 737 PAVALSTIPGAVPITP--PITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIM 794 T P A TP P + AA P P + ++V P P P + Sbjct: 1038 EP----TSPAAAVPTPEEPTSPAAAVPTPEEPTSPA-AAVPTPEEPTSPAAAVPTPEEPT 1092 Query: 795 RPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPR------KKPRKQQHVISTEEG 848 P +AVP T SP+ A +PT + P ASP ++P + T E Sbjct: 1093 SPAAAVPTPEEPT-SPAAA-------VPTPEEP--ASPAAAVPTPEEPASPAAAVPTPEE 1142 Query: 849 DMMETNS--TDDEKSTAKSLLVKAEKRKSP 876 + T +E ++A + E+ SP Sbjct: 1143 PAFPAPAVPTPEESASAAVAVPTPEESASP 1172 >gi|148612809 WNK lysine deficient protein kinase 1 [Homo sapiens] Length = 2382 Score = 74.3 bits (181), Expect = 6e-13 Identities = 162/676 (23%), Positives = 254/676 (37%), Gaps = 115/676 (17%) Query: 239 VMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPI-QSRPPVTTSNAIPPAVVATVSATR 297 + +SS + PTS L + A + I P+ +SR + S P + TV+A+ Sbjct: 1231 IPASSMPQQIGIPTSSLTQVVHS--AGRRFIVSPVPESR--LRESKVFPSEITDTVAAST 1286 Query: 298 AQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSH--PALGT 355 AQSP + + H+ S LS+Q A ++R + T SH P Sbjct: 1287 AQSPGMNLS--HSASS------LSLQQ---AFSELRRAQMTEGPNTAPPNFSHTGPTFPV 1335 Query: 356 PKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSV-SHTQAPTST----IVT 410 L ++A G P AA AP+ AT++ P+ + + S PT + T Sbjct: 1336 VPPFLSSIA-------GVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIAGVAT 1388 Query: 411 MT----------VPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPIS 460 T P S + S+I + VV I+ TSP +Q P S ++ +S Sbjct: 1389 STGVVTSGGLPIPPVSESPVLSSVVSSITIPAVV--SISTTSPSLQ--VPTSTSEIV-VS 1443 Query: 461 GHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVS 520 P+ T + S P S + T +SVST +P + Sbjct: 1444 STALYPSVTVSATSASAGGSTATPGPK--PPAVVSQQAAGSTTVGATLTSVSTTTSFPST 1501 Query: 521 AQAPNSAITAQTGVG-VASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTP 579 A + +++ T +A TV ++ L S + AP S+ A + + Sbjct: 1502 ASQLSIQLSSSTSTPTLAETVVVSAHSLDKTSHSSTTGLAFSLSAPSSSSS-PGAGVSSY 1560 Query: 580 GIQPA---PLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISN 636 QP PL + ++TPI PQ G TS +L +I P+ Sbjct: 1561 ISQPGGLHPLVIPSVIASTPI-------------LPQAAGPTSTPLLPQVPSIP--PLVQ 1605 Query: 637 PFSAAPAAT-TVVQTHSQSA------STNAPAQGSSPRPSILRKKPATDGAKPK------ 683 P + PA T++ + Q A T+ P S +P K P D K Sbjct: 1606 PVANVPAVQQTLIHSQPQPALLPNQPHTHCPEVDSDTQP----KAPGIDDIKTLEEKLRS 1661 Query: 684 --SEIHVSMATPVTVSMETV----SNQNNDQPTIAVPPTAQQ--------PPPTIP--TM 727 SE S A +VS+ET S PT AV P+ PP +P T+ Sbjct: 1662 LFSEHSSSGAQHASVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTV 1721 Query: 728 IAAASP---PSQPAVALSTI-----PGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPV 779 +P P Q + +ST PG P PP+T P + G+L S PP Sbjct: 1722 ALPVTPVVTPGQVSTPVSTTTSGVKPGTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPF 1781 Query: 780 PEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQ 839 P + + +P++ + T+SP + + + + P S P A + Q Sbjct: 1782 PGPSLTQSQQPLE------DLDAQLRRTLSPEMITVTSAVG-PVSMAAPTAITEAGTQPQ 1834 Query: 840 QHVISTEEGDMMETNS 855 + V +EG ++ T+S Sbjct: 1835 KGVSQVKEGPVLATSS 1850 Score = 65.9 bits (159), Expect = 2e-10 Identities = 185/914 (20%), Positives = 315/914 (34%), Gaps = 107/914 (11%) Query: 16 GAGGGRRLQVEMSSQQFPRLG-----APSTGL--SQAPSQI-ANSGSAGLINPAATVNDE 67 G G + +SSQQ G A STG PS + A S G+ P++ + Sbjct: 658 GQGSSVFTESRVSSQQTVSYGSQHEQAHSTGTVPGHIPSTVQAQSQPHGVYPPSSVAQGQ 717 Query: 68 SGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAH 127 S S+ +SSS +Q +++Q + + P Q + + S + A TA P Sbjct: 718 SQGQPSSSSLTGVSSSQPIQHPQQQQG--IQQTAPPQQTVQYSLSQTSTSSEATTAQPVS 775 Query: 128 L--TPAVPLSFSEGLMKP--PPKPTMPSRPIAPAPPSTLSLPPKVPGQ-VTVTMESSIPQ 182 P V S G P P PT+ P P +P + V P Sbjct: 776 QPQAPQVLPQVSAGKQLPVSQPVPTIQGEPQIPVATQPSVVPVHSGAHFLPVGQPLPTPL 835 Query: 183 ASAIPVATISGQQGHPSNLHHIMTTNVQMSII----RSNAPGPPLHIGASHLPRGAAAAA 238 PV+ I P + H+ T S + + P L + +S + Sbjct: 836 LPQYPVSQI------PISTPHVSTAQTGFSSLPITMAAGITQPLLTLASSATTAAIPGVS 889 Query: 239 VMSSSKVTTVLRPTSQLPNAA---TAQPAVQHI---IHQPIQSRPPVTTSNAI----PPA 288 + S++ T+L+P +QLP+ QPAVQ + + + P+++ + + PP Sbjct: 890 TVVPSQLPTLLQPVTQLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPR 949 Query: 289 VVATV--SATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRIT 346 + + A S + + H+T + PT + P +Q +S + Sbjct: 950 LPPQYPGDSNIAPSSNVASVCIHSTVLSPPMPTEVLATPGYFPTVVQPYVESNLLVPMGG 1009 Query: 347 LPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTS 406 + + P L AQ S+ V +T + P+ A V+ TQA Sbjct: 1010 VGGQVQVSQPGGSL---AQAPTTSSQQAVLESTQG---VSQVAPAEPVA--VAQTQATQP 1061 Query: 407 TIVTMTVPS-HSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRAS 465 T + +V S HS A+ ++ N V + T+ R R S+ S H + Sbjct: 1062 TTLASSVDSAHSDVASGMSDGNENVPSSSGRHEGRTTKRHY------RKSVRSRSRHEKT 1115 Query: 466 PNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPN 525 P N+ V+ Q L H +T ++ + P Sbjct: 1116 SRPKLRILNVSNKGDRVVECQ------------LETHNRKMVTF------KFDLDGDNPE 1157 Query: 526 SAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGI--QPAPISTQGIQPAPIGTPGIQP 583 T N L S ++ I + + ++ + P G G++ Sbjct: 1158 EIATIMVN---------NDFILAIERESFVDQVREIIEKADEMLSEDVSVEPEGDQGLES 1208 Query: 584 AP-LGTQGIHSATPINTQGLQPAPMGTQQPQ---PEGKTSAVVLADGATIVANPI----- 634 G + + + QP P + Q P + VV + G + +P+ Sbjct: 1209 LQGKDDYGFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRL 1268 Query: 635 -SNPFSAAPAATTVVQTHSQSASTNAPAQGSS----PRPSILRKKPATDGAK--PKSEIH 687 + + TV + +QS N SS S LR+ T+G P + H Sbjct: 1269 RESKVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAPPNFSH 1328 Query: 688 VSMATPVTVS-METVSNQNNDQPTIAVPPTAQQPPPTIPTMI--AAASPPSQPAVALSTI 744 PV + +++ A P PP I T + + + P++ +A Sbjct: 1329 TGPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQSEVTVPTEEGIA---- 1384 Query: 745 PGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLA 804 V + + T P P V+ LSSV+ V + P S + Sbjct: 1385 --GVATSTGVVTSGGLPIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEIVV 1442 Query: 805 TNT-VSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTA 863 ++T + PS+ + A + S S PG P +Q +T + ++T STA Sbjct: 1443 SSTALYPSVTVSATSASAGGSTATPGPKPPAVVSQQAAGSTTVGATLTSVSTTTSFPSTA 1502 Query: 864 KSLLVKAEKRKSPP 877 L ++ S P Sbjct: 1503 SQLSIQLSSSTSTP 1516 Score = 53.5 bits (127), Expect = 1e-06 Identities = 173/778 (22%), Positives = 275/778 (35%), Gaps = 165/778 (21%) Query: 16 GAGGGRRLQVEM-----SSQQFPRLGAPSTGLSQAPSQIANSGSAGLINPAATVNDESGR 70 G G ++L+ E +S ++G P++ L+Q + ++G +++P V + R Sbjct: 1216 GFSGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQV---VHSAGRRFIVSP---VPESRLR 1269 Query: 71 DSEVSARE------------------HMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHH- 111 +S+V E H +SS SLQ + + P + H Sbjct: 1270 ESKVFPSEITDTVAASTAQSPGMNLSHSASSLSLQQAFSELRRAQMTEGPNTAPPNFSHT 1329 Query: 112 ------------AVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRP-IAPAP 158 ++A A P T + P S +++ + T+P+ IA Sbjct: 1330 GPTFPVVPPFLSSIAGVPTTAAATAPVPATSSPPNDISTSVIQS--EVTVPTEEGIAGVA 1387 Query: 159 PST-------LSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQM 211 ST L +PP V ++ SSI + + ++T S P++ I Sbjct: 1388 TSTGVVTSGGLPIPPVSESPVLSSVVSSITIPAVVSISTTSPSLQVPTSTSEI------- 1440 Query: 212 SIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQ 271 ++ S A P + + A TS +TA P Sbjct: 1441 -VVSSTALYPSVTVSA------------------------TSASAGGSTATPG------- 1468 Query: 272 PIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAIS 331 +PP S A TV AT + V TTT+ +T S LS S P+ A + Sbjct: 1469 ---PKPPAVVSQ--QAAGSTTVGAT--LTSVSTTTSFPSTASQLSIQLSSSTSTPTLAET 1521 Query: 332 IQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAP-ILATNTIP 390 + A S D T SH + T A + S G V++ P L IP Sbjct: 1522 VVVSAHSLDKT------SHSS--TTGLAFSLSAPSSSSSPGAGVSSYISQPGGLHPLVIP 1573 Query: 391 SATTAGSV-SHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDY 449 S + + PTST + VPS V +N+P V Q + H+ P QP Sbjct: 1574 SVIASTPILPQAAGPTSTPLLPQVPSIPPLVQPV--ANVP---AVQQTLIHSQP--QP-- 1624 Query: 450 PAERSSLIPISGHRASPNPVAMETRSDNRPSVP------VQFQYFLPTYPPSAYPLAAHT 503 +L+P H P E SD +P P + + + A H Sbjct: 1625 -----ALLPNQPHTHCP-----EVDSDTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHA 1674 Query: 504 YTPITSSV---STIRQ-YPVSAQAPNSAITAQTGVGVAST-VHLNPMQLMTVDASHARHI 558 + +S+ ST+ P +A AP+ +T+ T + T + L + L + Sbjct: 1675 SVSLETSLVIESTVTPGIPTTAVAPSKLLTSTTSTCLPPTNLPLGTVALPVTPVVTPGQV 1734 Query: 559 QGIQPAPISTQGIQPAPIGTPGIQP-------APLGTQGIHSATPINTQGLQPAPMGTQQ 611 P +T G++P GT +P P+GT+ P P P TQ Sbjct: 1735 S--TPVSTTTSGVKP---GTAPSKPPLTKAPVLPVGTELPAGTLPSEQLPPFPGPSLTQS 1789 Query: 612 PQPEGKTSAVV---LADGATIVANPISNPFSAAPAATTVVQTHSQ---SASTNAPAQGSS 665 QP A + L+ V + + AAP A T T Q S P +S Sbjct: 1790 QQPLEDLDAQLRRTLSPEMITVTSAVGPVSMAAPTAITEAGTQPQKGVSQVKEGPVLATS 1849 Query: 666 PRPSILRK-----KPATDGA----KPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVP 714 + + A DGA K KSE S+ + S +V + ++ + T+ P Sbjct: 1850 SGAGVFKMGRFQVSVAADGAQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLVKP 1907 Score = 46.2 bits (108), Expect = 2e-04 Identities = 99/449 (22%), Positives = 161/449 (35%), Gaps = 71/449 (15%) Query: 322 IQHPPSAAISIQRPA-QSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATV 380 I+ PSA+ I + S V+T++ P P +Q + ++ S GT + Sbjct: 603 IKQLPSASTGIPTASTTSASVSTQVE-PEEPEADQHQQLQYQQPSISVLSDGTVDSGQGS 661 Query: 381 APILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITH 440 + + T + H QA + T TVP H + V + P P + Sbjct: 662 SVFTESRVSSQQTVSYGSQHEQAHS----TGTVPGHI--PSTVQAQSQPHGVYPPSSVAQ 715 Query: 441 TSPRIQPDYPAERSSLIPISGHRASPNPVAME-TRSDNRPSVPVQF---QYFLPTYPPSA 496 + QP SSL +S + +P + + P VQ+ Q + +A Sbjct: 716 GQSQGQP----SSSSLTGVSSSQPIQHPQQQQGIQQTAPPQQTVQYSLSQTSTSSEATTA 771 Query: 497 YPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHAR 556 P++ + VS +Q PVS P I + + VA+ + P+ +H Sbjct: 772 QPVSQPQAPQVLPQVSAGKQLPVSQPVP--TIQGEPQIPVATQPSVVPVH----SGAHFL 825 Query: 557 HIQGIQPAPISTQ-GIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPE 615 + P P+ Q + PI TP + A G S+ PI G QP Sbjct: 826 PVGQPLPTPLLPQYPVSQIPISTPHVSTAQTG----FSSLPITMAA------GITQP--- 872 Query: 616 GKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKP 675 + LA AT +A P +TVV S P++L +P Sbjct: 873 ----LLTLASSATT---------AAIPGVSTVV---------------PSQLPTLL--QP 902 Query: 676 ATDGAKPKSEIHVSMATPVTVSMETVSN--QNNDQPTIAVPPTAQQPPPTIPTMIAAASP 733 T + S++H + P SM +N Q + P + Q PP +P S Sbjct: 903 VT---QLPSQVHPQLLQPAVQSMGIPANLGQAAEVPLSSGDVLYQGFPPRLPPQYPGDSN 959 Query: 734 PSQPAVALSTIPGAVPITPPITTIAAAPP 762 + + S + ++PP+ T A P Sbjct: 960 IAPSSNVASVCIHSTVLSPPMPTEVLATP 988 Score = 32.0 bits (71), Expect = 3.1 Identities = 44/166 (26%), Positives = 63/166 (37%), Gaps = 34/166 (20%) Query: 639 SAAPAATTVVQTH-----SQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATP 693 S AATT H S +NA A P L +P+ A P+S A P Sbjct: 65 SRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSL-PQPSIPAAVPQS------APP 117 Query: 694 VTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAV---ALSTIPGAV-- 748 ETV+ A AQQPP AA+ P + AV A ST+P + Sbjct: 118 EPHREETVT-------ATATSQVAQQPP--------AAAAPGEQAVAGPAPSTVPSSTSK 162 Query: 749 --PITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMD 792 P++ P + PP G S P + ++++E ++ Sbjct: 163 DRPVSQPSLVGSKEEPPPARSGSGGGSAKEPQEERSQQQDDIEELE 208 >gi|148612879 polyhomeotic like 3 [Homo sapiens] Length = 995 Score = 74.3 bits (181), Expect = 6e-13 Identities = 150/685 (21%), Positives = 249/685 (36%), Gaps = 112/685 (16%) Query: 288 AVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITL 347 AV A++S+ R P + T + S++S+ ++++ P+ A I R S + IT Sbjct: 110 AVQASLSSGR---PSTSPTGSVTQQSSMSQTSINLSTSPTPAQLISRSQASSSTSGSITQ 166 Query: 348 PS------HPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHT 401 + P L + Q++ AQ IF+ T VAA + I ++ S++ + + Sbjct: 167 QTMLLGSTSPTLTASQAQMYLRAQMLIFTPATTVAAVQ-SDIPVVSSSSSSSCQSAATQV 225 Query: 402 QAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISG 461 Q T + V S S + +TS + + T TS +I P+ S+ S Sbjct: 226 QNLTLRSQKLGVLSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESP 285 Query: 462 HRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSA 521 S + T S ++ P + P + L H P+ S S + + + Sbjct: 286 SLESRSTAVTRTSSIHQLIAPASYS------PIQPHSLIKHQQIPLHSPPSKVSHHQLIL 339 Query: 522 QAPN---SAITAQTGV-GVASTVHLNPMQ-------LMTVDASHARHIQGIQPAPISTQG 570 Q IT Q + H P+Q + H IQ P+P++ Sbjct: 340 QQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQS-HPSPLTVSP 398 Query: 571 -----------IQPAPIGTPGIQPA-PLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKT 618 + P P +P P + Q + P+ + LQP P Q + + Sbjct: 399 NQSQSAQQSVVVSPPPPHSPSQSPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQA 458 Query: 619 SA-------VVLADGATIVANPISNPFSAAPAATTVVQTHSQ-SASTNAPAQGSSPRPSI 670 +A + L + P+ +P V +H Q S+ ++P +SP P + Sbjct: 459 TAQLNLPSHLPLPASPVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASP-PQM 517 Query: 671 LRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQN---NDQPTIAVPPTAQQPPPTIPTM 727 PA P + P +S V QN +++ A Q P T+P Sbjct: 518 STSPPAQIPPLPLQSMQSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLP-- 575 Query: 728 IAAASPPSQPAVALSTIPGAVPITPPI-------------------TTIAAAPPP----- 763 PP AV L P A P+ PP+ + PPP Sbjct: 576 -----PPQTVAVNLQVQPPA-PVDPPVVYQVEDVCEEEMPEESDECVRMDRTPPPPTLSP 629 Query: 764 -SVTVGGS---------LSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLA 813 ++TVG L V P V + P D PPL + P+ Sbjct: 630 AAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDPSHVSVPPPPL----LLPAAT 685 Query: 814 LLANNLSMPTS-----DLPPGASPRKKPRKQQHVISTEEGDMMETNSTDDEKSTAKSLLV 868 +N+ SM +S + PP A KP+ HVI EG +++ + + SLL+ Sbjct: 686 TRSNSTSMHSSIPSIENKPPQAI--VKPQILTHVI---EGFVIQ-EGLEPFPVSRSSLLI 739 Query: 869 KAEKRKSPPKEYIDEEGVRYVPVRP 893 + +K P +D + + V V+P Sbjct: 740 EQPVKKRP---LLDNQVINSVCVQP 761 Score = 38.5 bits (88), Expect = 0.033 Identities = 95/490 (19%), Positives = 180/490 (36%), Gaps = 101/490 (20%) Query: 33 PRLGAPSTGLSQAPS--QIANSGSAGLINPAATVNDES----GRDSEVSAREHMSSSSSL 86 P L + ST +++ S Q+ S I P + + + S+VS + + L Sbjct: 285 PSLESRSTAVTRTSSIHQLIAPASYSPIQPHSLIKHQQIPLHSPPSKVSHHQLI-----L 339 Query: 87 QSREEKQEPVVVRPYPQVQMLSTH------HAVASA---------TPVAVTAPPAHLTPA 131 Q ++++ +P+ ++ Q S H H + A +P+ P ++P Sbjct: 340 QQQQQQIQPITLQNSTQDPPPSQHCIPLQNHGLPPAPSNAQSQHCSPIQSHPSPLTVSPN 399 Query: 132 VPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATI 191 S + ++ PP P PS+ T+ + PQA P + Sbjct: 400 QSQSAQQSVVVSPPPPHSPSQ------------------SPTIIIH---PQALIQPHPLV 438 Query: 192 SGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRP 251 S NL T N + + N P SHLP A+ + + + ++ P Sbjct: 439 SSALQPGPNLQQ-STANQVQATAQLNLP--------SHLPLPASPVVHIGPVQQSALVSP 489 Query: 252 TSQLPNAATAQPAVQHIIHQPIQSRPPVTTS--NAIPPAVVATVSATR------------ 297 Q+ + + Q + PI S P ++TS IPP + ++ + + Sbjct: 490 GQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPPAQIPPLPLQSMQSLQVQPEILSQGQVL 549 Query: 298 AQSPVITTTAAHATDSALSRPTLSIQHPPSAAIS--IQRPA--------QSRDVTTR--- 344 Q+ +++ A ++ + P ++ P + A++ +Q PA Q DV Sbjct: 550 VQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVDPPVVYQVEDVCEEEMP 609 Query: 345 ------ITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSV 398 + + P T T+ + ++ P+ P +A+ + + Sbjct: 610 EESDECVRMDRTPPPPTLSPAAITVGRGEDLTSEHPLLEQVELPAVASVSASVIKSPSDP 669 Query: 399 SHTQAPTSTIV----TMTVPSHSSHATAVTTSNIPVAKVV-PQQITHT------SPRIQP 447 SH P ++ T S S H++ + N P +V PQ +TH ++P Sbjct: 670 SHVSVPPPPLLLPAATTRSNSTSMHSSIPSIENKPPQAIVKPQILTHVIEGFVIQEGLEP 729 Query: 448 DYPAERSSLI 457 +P RSSL+ Sbjct: 730 -FPVSRSSLL 738 >gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 673 Score = 73.6 bits (179), Expect = 9e-13 Identities = 162/713 (22%), Positives = 256/713 (35%), Gaps = 103/713 (14%) Query: 165 PPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLH 224 P + P + + T S + P + + G PS T ++ + R++ G P Sbjct: 4 PTRTPSRASPTRTPSTASLTGTP--SRASLTGTPS------TASLMGTPSRASLTGTPPR 55 Query: 225 IGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNA 284 AS + A+ ++S S+ + +S L T P++ + P ++ T A Sbjct: 56 --ASLKGTTSMASLMVSPSRASLTRMQSSSL---LTRTPSMASLKRMPPRASRTRTLPRA 110 Query: 285 IPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTR 344 +T S TR+ S TT SR +LS+ +AA+ Sbjct: 111 SLMRRPSTASLTRSPSRASLTTTP-------SRASLSMTPSTAAAL-------------- 149 Query: 345 ITLPSHPALG-TPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQA 403 T+PS +L TP + TM T T TP A+ T+ +TA S T+ Sbjct: 150 -TMPSRASLTRTPPRASLTMTPSTASLTRTPPRASPTGMPSRTSPTGMPSTA---SLTKM 205 Query: 404 PTSTIVTMTVPSHSSHAT---AVTTSNIPVAKVVPQQIT----HTSPRIQPDYPAERSSL 456 ++ +T T+ S T A T + P A + T T PR P R+SL Sbjct: 206 DSTASITRTLSRASPTGTPPRASPTGSPPRASLSMMPSTALLIRTPPRASPTGMLSRTSL 265 Query: 457 I-----------PISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYT 505 P ASP PS LP P+ L+ + T Sbjct: 266 TKMDSTASITRTPSRPSTASPTGTPSRASLSMTPST-ASLMRMLPRASPTGM-LSRTSLT 323 Query: 506 PITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAP 565 + S+ S R P ++ + + TG ++ P + + + G+ + Sbjct: 324 KMDSTASISRTPPRASITRTPSRASPTGKPSTASPTGTPSRASPTGSPSTASLTGLS-ST 382 Query: 566 ISTQGIQP--APIGTPGI-----QPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKT 618 S G P +P GTP +P G+ S T I +P T+ P T Sbjct: 383 ASPTGTPPRASPTGTPSTASLTRKPPRASPTGMLSRTSITKMDSTASP--TRTPPRASPT 440 Query: 619 SAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPA--------QGSSPRPSI 670 G A+P P A+P T + + S ST +P GS R S+ Sbjct: 441 -------GTPPRASPTGTPSRASPTGTQSTASPTGSPSTASPTGSPSTASPTGSPSRASL 493 Query: 671 LRKKPATDGAKPKSEIHV----SMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPT 726 R K +S + S A+P T + T S + +A+ ++ P+ Sbjct: 494 TRTPSRASLTKMESTASITRTPSRASP-TWTPSTASPTGSPSTALAMGSPSRAALTRTPS 552 Query: 727 MIAAASPPSQPAVALSTIPGAVPIT-PPITTIAAAPPPSVTVGG--SLSSVLGPPVPEIK 783 + PS+ ++ T P +T P T + PPS + G S +S G P + Sbjct: 553 RASLTRTPSRASL---TTPSRASLTRTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSALL 609 Query: 784 VKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKP 836 K MD ++ PP A+ T +P A+ P P G PR P Sbjct: 610 TK-----MDSTASITRTPPRASPTETPP---RASPTGTPPRASPTGTPPRASP 654 Score = 48.9 bits (115), Expect = 2e-05 Identities = 126/533 (23%), Positives = 189/533 (35%), Gaps = 101/533 (18%) Query: 122 TAPPAHLTPAVPLSFSEGLMKPPPKPT-MPSRPIAPAPPSTLSL---------------- 164 T P A LT P + S P PT MPSR PST SL Sbjct: 160 TPPRASLT-MTPSTASLTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRA 218 Query: 165 -----PPKVP--GQVTVTMESSIPQASAI----PVATISGQQGHPSNLHHIMTTNVQMSI 213 PP+ G S +P + + P A+ +G S T ++ + Sbjct: 219 SPTGTPPRASPTGSPPRASLSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTP 278 Query: 214 IRSNAPGP---PLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQ----PAVQ 266 R + P P S P A+ ++ + T +L TS +TA P Sbjct: 279 SRPSTASPTGTPSRASLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRA 338 Query: 267 HIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPP 326 I P ++ P S A P + S T + S T + + P S P Sbjct: 339 SITRTPSRASPTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPTGTPPRASPTGTP 398 Query: 327 SAAISIQRPAQ-------SRDVTTRI-----------------TLPSHPALGTPKQQLHT 362 S A ++P + SR T++ T P GTP + T Sbjct: 399 STASLTRKPPRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASPT 458 Query: 363 MAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATA 422 Q T TG+P +T +P + +T S T +P+ +T T PS +S Sbjct: 459 GTQSTASPTGSP---STASPTGSPST---------ASPTGSPSRASLTRT-PSRASLTKM 505 Query: 423 VTTSNIPVAKVVPQQITHTSPRIQPDY-PAERSSLIPISGHRASPNPV-AMETRSDNRPS 480 +T++ IT T R P + P+ S S A +P A TR+ +R S Sbjct: 506 ESTAS----------ITRTPSRASPTWTPSTASPTGSPSTALAMGSPSRAALTRTPSRAS 555 Query: 481 VPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTI--RQYPVSAQAPNSAITAQTGVGVAS 538 + T PS L + +T + ST+ + P SA +P + + G+ S Sbjct: 556 L---------TRTPSRASLTTPSRASLTRTPSTVLLTRMPPSA-SPTGMPSRTSPTGMPS 605 Query: 539 TVHLNPM-QLMTVDASHARHIQGIQPAPISTQGIQP--APIGTPGIQPAPLGT 588 + L M ++ + R P S G P +P GTP + +P GT Sbjct: 606 SALLTKMDSTASITRTPPRASPTETPPRASPTGTPPRASPTGTPP-RASPTGT 657 >gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens] Length = 987 Score = 73.6 bits (179), Expect = 9e-13 Identities = 166/712 (23%), Positives = 255/712 (35%), Gaps = 122/712 (17%) Query: 81 SSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGL 140 S++ L+S ++ Q P + P P+ A A +PP + PL S+ Sbjct: 328 STNPLLESLKKMQTPPSLPPCPES---------AGAATTEALSPPKTPSLLPPLGLSQS- 377 Query: 141 MKPP---PKPTMPSRP------IAPAP---PST-LSLPPKVPGQVTVTMESSIPQASAIP 187 PP P P+ S+P + PAP P+T PP + + +++ + A Sbjct: 378 -GPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPK 436 Query: 188 VATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSK--- 244 + + G Q + + + + PP P G + A SS Sbjct: 437 QSFLFGTQNTSPSSPAAPAASSASPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLP 496 Query: 245 -VTTVLRPTSQLPNAATAQPAVQHIIHQPI--QSRPPVTTSNAIPPAVVATVSATRAQSP 301 T+ PT Q P ++ P + P Q+ P T P SAT A +P Sbjct: 497 TTTSTTAPTFQ-PVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAP 555 Query: 302 VITTTAAHATDSALSRPTLS--IQHPPSAAISIQRPAQSRDVTTRITLPSHPAL-GTPKQ 358 + T+A+ +TDSA S+P I S+++S T+ T S P L G P+ Sbjct: 556 I--TSASPSTDSA-SKPAFGFGINSVSSSSVST--------TTSTATAASQPFLFGAPQA 604 Query: 359 QL--HTMAQKTIFSTGTPVAAATVAPILATN-----TIPSATTAGSVSHT----QAPTST 407 T A +IF G P A T + + +P+AT++ + + TS Sbjct: 605 SAASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTAVPTATSSSAADFSGFGSTLATSA 664 Query: 408 IVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPN 467 T + P+ + T+ T NIP + P YP P G Sbjct: 665 PATSSQPTLTFSNTSTPTFNIPFGSSAKSPL--------PSYPGANPQ--PAFGAAEGQP 714 Query: 468 PVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSA 527 P A + PS F T+ SA P A TP +S I V A P Sbjct: 715 PGAAKPALT--PSFGSSF-----TFGNSAAPAPATAPTPAPASTIKI----VPAHVPT-- 761 Query: 528 ITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLG 587 P+Q A+H+ G++ +T AP + QPA G Sbjct: 762 ----------------PIQPTFGGATHSAF--GLK----ATASAFGAPASS---QPAFGG 796 Query: 588 TQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTV 647 + + S + G T Q G +S+V G+T +P + SAAPA + Sbjct: 797 STAVFSFGAATSSGFG----ATTQTASSGSSSSVF---GST-TPSPFTFGGSAAPAGSGS 848 Query: 648 ----VQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSN 703 V T SA+T A + G+ S P T G + +TP ++ + + Sbjct: 849 FGINVATPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTE 908 Query: 704 QNNDQPTIAVPPTAQQ-PPPTIPT-----MIAAASPPSQPAVALSTIPGAVP 749 A P Q P P + T A+S P+Q V + A P Sbjct: 909 SKPVFGGTATPTFGQNTPAPGVGTSGSSLSFGASSAPAQGFVGVGPFGSAAP 960 Score = 52.0 bits (123), Expect = 3e-06 Identities = 134/609 (22%), Positives = 205/609 (33%), Gaps = 100/609 (16%) Query: 241 SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQS 300 SSS ++ SQ P + + + H S P +A ++ + Sbjct: 168 SSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTP------------LAADKESQGEK 215 Query: 301 PVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALG------ 354 TT ++ S P S Q + R + ++TLP P LG Sbjct: 216 AADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGE------QLTLPPPPQLGYSITAE 269 Query: 355 ----TPKQQLHTMAQKTIFSTGTPVAAATVAPILA----TNTIPSATTAGSVSHTQAPTS 406 K L Q + + T P T T+P+A TA PTS Sbjct: 270 DLDLEKKASLQWFNQALEDKSDAASNSVTETPPTTQPSFTFTLPAAATASP------PTS 323 Query: 407 TIVTMTVPSHSSHATAVTTSNIPVAKVVPQQI-THTSPRIQPDYPAERSSLIPISGHRAS 465 + T P S T ++P P+ T+ + P P S L P+ ++ Sbjct: 324 LLAPSTNPLLESLKKMQTPPSLPPC---PESAGAATTEALSP--PKTPSLLPPLGLSQSG 378 Query: 466 PNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPN 525 P + D++P P +P PS P A T P T T + P + AP+ Sbjct: 379 PPGLLPSPSFDSKP--PTTLLGLIPA--PSMVP-ATDTKAPPTLQAETATK-PQATSAPS 432 Query: 526 SAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAP 585 A G +T +P AS + I AP ++ P P G P+ Sbjct: 433 PAPKQSFLFGTQNTSPSSPAAPAASSASPM--FKPIFTAPPKSEKEGPTPPG-----PSV 485 Query: 586 LGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAAT 645 T S+ P T P T QP V + + P+ PF Sbjct: 486 TATAPSSSSLPTTTSTTAP----TFQP---------VFSSMGPPASVPLPAPFFKQTTTP 532 Query: 646 TVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGA-KPKSEIHVSMATPVTVSMETVSNQ 704 T + T + S+ P I P+TD A KP ++ + +VS T + Sbjct: 533 ATAPTTTAPLFTGLASATSAVAP-ITSASPSTDSASKPAFGFGINSVSSSSVSTTTSTAT 591 Query: 705 NNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPS 764 QP + P A AA+ P+ ++ P A+P T +TT + + P + Sbjct: 592 AASQPFLFGAPQAS----------AASFTPAMGSIFQFGKPPALPTTTTVTTFSQSLPTA 641 Query: 765 VTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTS 824 V S S+ D S + A T S L +N S PT Sbjct: 642 VPTATSSSAA-----------------DFSGFGSTLATSAPAT-SSQPTLTFSNTSTPTF 683 Query: 825 DLPPGASPR 833 ++P G+S + Sbjct: 684 NIPFGSSAK 692 Score = 46.2 bits (108), Expect = 2e-04 Identities = 83/389 (21%), Positives = 136/389 (34%), Gaps = 94/389 (24%) Query: 470 AMETRSDNRPSVPVQFQYFLPTYPPSAYP--LAAHTYTPITSSVSTIRQYPVSAQAPNSA 527 A + ++ P+ F + LP ++ P L A + P+ S+ ++ P P SA Sbjct: 293 ASNSVTETPPTTQPSFTFTLPAAATASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESA 352 Query: 528 ITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLG 587 G A+T L+P + P+ + G+ + G PG+ P+P Sbjct: 353 -------GAATTEALSPPKT---------------PSLLPPLGLSQS--GPPGLLPSP-- 386 Query: 588 TQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTV 647 S P GL PAP + P + K + A+ AT Sbjct: 387 --SFDSKPPTTLLGLIPAP--SMVPATDTKAPPTLQAETAT------------------- 423 Query: 648 VQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNND 707 + +T+AP+ +P+ S L T + P + S A+P+ Sbjct: 424 -----KPQATSAPSP--APKQSFLFGTQNTSPSSPAAPA-ASSASPMF------------ 463 Query: 708 QPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTV 767 +P PP +++ PT P A+ PS ++ +T A P +++ PP SV Sbjct: 464 KPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSSM--GPPASV-- 519 Query: 768 GGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLP 827 P+P K+ P A P T + LA A + P + Sbjct: 520 ----------PLPAPFFKQTTTP--------ATAPTTTAPLFTGLA-SATSAVAPITSAS 560 Query: 828 PGASPRKKPRKQQHVISTEEGDMMETNST 856 P KP + S + T ST Sbjct: 561 PSTDSASKPAFGFGINSVSSSSVSTTTST 589 >gi|171460948 TSC22 domain family, member 1 isoform 1 [Homo sapiens] Length = 1073 Score = 71.2 bits (173), Expect = 5e-12 Identities = 183/899 (20%), Positives = 318/899 (35%), Gaps = 115/899 (12%) Query: 9 AGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINPAATVNDES 68 A + A G G G SS+ FP PS L Q P A+S S P ++N S Sbjct: 38 ASALNAAGTGVGSNAT---SSEDFP---PPS--LLQPPPPAASSTSGPQPPPPQSLNLLS 89 Query: 69 GRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHL 128 + + ++ + ++ + V P +S+++++A T +H Sbjct: 90 QAQLQA---QPLAPGGTQMKKKSGFQITSVTPAQISASISSNNSIAEDTESYDDLDESHT 146 Query: 129 TPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLS--LPPKVPGQVTVTMES-------S 179 LS SE L + T P + TL+ + PG V+ Sbjct: 147 ED---LSSSEILDVSLSRATDLGEPERSSSEETLNNFQEAETPGAVSPNQPHLPQPHLPH 203 Query: 180 IPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAV 239 +PQ + + I+G HP +LHH + + + + + ++ + G ++ V Sbjct: 204 LPQQNVV----INGN-AHPHHLHHHHQIHHGHHLQHGHHHPSHVAVASASITGGPPSSPV 258 Query: 240 M------SSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATV 293 SS T + PTS + ++ + + ++ R P TT +V T Sbjct: 259 SRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNM-------RAPSTTGGIGINSVTGTS 311 Query: 294 SATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPAL 353 + + + + T S L +S + PSAA P + V I Sbjct: 312 TVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGNGT 371 Query: 354 GTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTMTV 413 + + ++ TG V++ P + T+ S + T Sbjct: 372 ISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYE 431 Query: 414 PSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMET 473 ++ AT N V V I TS R + SS+ +S + S M Sbjct: 432 KENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEM-- 489 Query: 474 RSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTG 533 P+V VQ Q P V T++Q + P S Sbjct: 490 ---GAPTVVVQQQQ---------QQQQQQQQQPALQGV-TLQQMDFGSTGPQSIPAVSIP 536 Query: 534 VGVASTVHLNPMQLMTVDASHARHIQGIQPAPI-----STQGIQPAPIGTPGIQPAPLGT 588 ++ + ++ +QL + + S+ + QG+QP P+ + GIQP+P+ G+ A LG Sbjct: 537 QSISQS-QISQVQLQSQELSYQQK-QGLQPVPLQATMSAATGIQPSPVNVVGVTSA-LGQ 593 Query: 589 QGIHS------------ATPINT-----------QGLQPAPMGTQQPQPEGKTSAVVLAD 625 Q S A P+ T Q Q PM + Q P S Sbjct: 594 QPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPA 653 Query: 626 GATIVANPI-------SNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATD 678 + PI P SA A T V +Q P Q P+ + +PA Sbjct: 654 SEYVQQQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQ-----PTAVPAQPAGA 708 Query: 679 GAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPA 738 +P + +++ T S Q + PT P+ Q P P++I +PPS Sbjct: 709 SVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVP----PSVIQQGAPPSS-- 762 Query: 739 VALSTIPGAVP--ITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRP 796 +P A I + T A + P + + S + PP P + VEP+ Sbjct: 763 ---QVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQP-----QGVEPVAQGIV 814 Query: 797 VSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKKPRKQQHVISTEEGDMMETNS 855 +P +++ + S+++ + S S +P + P+ +T+ G+++++ S Sbjct: 815 SQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVS 873 Score = 35.8 bits (81), Expect = 0.22 Identities = 68/315 (21%), Positives = 109/315 (34%), Gaps = 48/315 (15%) Query: 29 SQQFPRLGAPSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVS---AREHMSSSSS 85 SQ P + P G + P Q+ G P + G V+ A E++ Sbjct: 608 SQAAPPVQTPLPG-APPPQQL----QYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPI 662 Query: 86 LQSREEKQEP----------VVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLS 135 LQ+ +P V+ PQ L A P + P PA + Sbjct: 663 LQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSA 722 Query: 136 FSEGLM--------KPPPKPTMPSRPIAP------APPSTLSLPPKVPGQVTVTMESSIP 181 G P PS + P APPS+ +PP G + +++S P Sbjct: 723 VPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAP 782 Query: 182 QASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMS 241 ++P + Q ++T Q + A G I + LP ++ + S Sbjct: 783 ---SLPQQLVIASQSS------LLTVPPQPQGVEPVAQG----IVSQQLPAVSSLPSA-S 828 Query: 242 SSKVTTVLRPT--SQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQ 299 S VT+ + T S +P+A T Q+I P + S + PP + + AQ Sbjct: 829 SISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQ 888 Query: 300 SPVITTTAAHATDSA 314 +++T A A Sbjct: 889 QIPLSSTQFSAQSLA 903 >gi|169205253 PREDICTED: hypothetical protein [Homo sapiens] Length = 3859 Score = 70.5 bits (171), Expect = 8e-12 Identities = 180/821 (21%), Positives = 278/821 (33%), Gaps = 127/821 (15%) Query: 95 PVVVRPYPQVQMLSTHHAVASATPV---AVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPS 151 PV P V + V S T AV PA +P VP++ ++G + P P Sbjct: 589 PVTPADSPVVPVTPADSPVLSVTLADSPAVPVTPAD-SPVVPVTPADGPVVPVASADSPF 647 Query: 152 RPIAPAPPSTLSLPPKVPGQVTVTMESS--IPQASA----IPVATISGQ------QGHPS 199 P+ PA +S+ P + VT S +P SA IPV T G+ G P Sbjct: 648 VPVTPADDPIVSVTPAESPAIPVTQADSPVVPVTSADRPVIPVTTADGRIVPVTAAGDPI 707 Query: 200 NLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAA 259 + + ++ PG P+ G + S V P + Sbjct: 708 -----------VPVTPADTPGSPVTSA-----DGPVVPVTSADSPFVPVTPPDGPVVPVT 751 Query: 260 TAQPAVQHIIHQPIQSR--PPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSR 317 +A V P+ S P V ++A P VA VS+ A PV+ T A A+ Sbjct: 752 SADGPV-----APVSSADGPVVPVTSADGP--VAPVSS--ADGPVVPVTPADTNGPAV-- 800 Query: 318 PTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPA---------LGTPKQQLHTMAQKTI 368 P S P I P +P PA +P + + Sbjct: 801 PVTSADSPFVPVIPADSPVVPVTPADDPIVPVTPADSSFVPVISADSPFVPVIPADGPVV 860 Query: 369 FSTGTPVAAATVAPI-------LATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHAT 421 + T V V P+ A T+ A S P +V P+ A Sbjct: 861 VDSSTDVLVVPVFPVNCILVPAFADETVVPLNPADSPVIPVTPPDDLVVPVTPTDCPVA- 919 Query: 422 AVTTSNIPVAKVVP-----QQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSD 476 VT+++ PV V P +T + P PA+ ++P++ + +PV T +D Sbjct: 920 PVTSADCPVVPVTPADSPADPVTAADGPVVPFTPAD-DPIVPVT---PADSPVVSVTPAD 975 Query: 477 NRPSVPVQF--QYFLPTYPPS----AYPLAAHTYTPITSSVSTIRQYPV-SAQAPNSAIT 529 P VPV F+P P + A P+T + S + PV SA P S +T Sbjct: 976 G-PVVPVASADSPFVPVTPADDPIVSVTPAESPAIPVTQADSPV--VPVTSADRPVSPVT 1032 Query: 530 AQTGVGVASTVHLNPMQLMT-VDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGT 588 G V T +P+ +T D + P T P TP P T Sbjct: 1033 TADGRIVPVTAAGDPIVPVTPADTPGSPVTSADGPVVPVTSADSPFVPVTPPDGPVVPVT 1092 Query: 589 QGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVV 648 P+++ P+ +G + V ADG + P +PF A + Sbjct: 1093 SADGPVAPVSSADGPVVPV----TSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDPI 1148 Query: 649 QTHSQSAS-------TNAPAQGSSPRPS-ILRKKPATDGAKPKSEIHVSMATPVTVSMET 700 + + S ++P +P S ++ PA P S + Sbjct: 1149 VPVTPADSPVLSVTLADSPVVPVTPADSPVIPVPPANGPVVPVSSADSPFVPVIPADGLV 1208 Query: 701 VSNQNND------QPT--IAVPPTAQQPPPTI---PTMIAAASPPSQPAVALSTIPG-AV 748 V + + D PT I VP A P ++ + + +P P V +++ V Sbjct: 1209 VLDSSTDVLVVPVSPTDGILVPDLADDPVVSVTIADSPVIPVTPADSPVVPVTSADSPVV 1268 Query: 749 PITP------------PITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPM----- 791 P+TP P+ ++ A P V V S+ P +P V P+ Sbjct: 1269 PVTPADSPVILVTPVGPVVSVTTADGPVVLV----STADSPVIPVTSADSPVVPVTPADG 1324 Query: 792 DIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASP 832 ++ SA P T + + P + P SP Sbjct: 1325 PVVPVTSADSPFVPVTPADDPIVPVTPADSPIVSVTPAESP 1365 Score = 66.2 bits (160), Expect = 1e-10 Identities = 151/723 (20%), Positives = 247/723 (34%), Gaps = 111/723 (15%) Query: 123 APPAHLTPA----VPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTME- 177 +P +TPA VP++ ++G + P +P P+ PA + P V+V Sbjct: 1593 SPVIPVTPADSTVVPVTLADGPVVPVTSVDIPVVPVTPANGPVAPVTPVDDPVVSVNPAD 1652 Query: 178 -SSIPQASA-IPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAA 235 S +P SA PV ++ G + + + A P + + + P Sbjct: 1653 GSVVPVTSADCPVVPVTPADG--------------LVVPVTPADSPIVPVTPADSPVVLV 1698 Query: 236 AAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRP----PVTTSNAIPPAVVA 291 +A VT P + +A T P P+ S PVT+++++P Sbjct: 1699 TSADSPVIPVTPADSPVVPVTSADTDSPG------SPVTSADGPVVPVTSADSLP----- 1747 Query: 292 TVSATRAQSPVITTTAAH---ATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLP 348 V T A PV+ T+A A S+ P + + S + + + D T +T Sbjct: 1748 -VPVTPADGPVVPVTSADGPVAPVSSADGPVVPVTPADSPVVPV---TTADDPTVPVTPA 1803 Query: 349 SHPALGTPKQQLHTMAQKTIFSTGTPVAAAT----------------------VAPILAT 386 P + P + + S PV A + P LA Sbjct: 1804 DSPVVPVPPANGPIVPVTSADSPFVPVIPADGLVVLDSSTDVLVVPVSPTDGILVPDLAD 1863 Query: 387 NTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQ-----ITHT 441 + + S T A S P + V + P+ VT+ + PV V P +T Sbjct: 1864 DPVVSVTIADSPVIPVTPADSPVVLVTPADGP-VVPVTSVDNPVVPVTPADNPVIPVTPV 1922 Query: 442 SPRIQPDYPAE------RSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPS 495 + P PA+ S+ PI + +PV T +D+ P +PV P P + Sbjct: 1923 DDPVVPVTPADDPIVPVTSADSPIVSVTPADSPVFPVTPADS-PVIPVA-SADSPLVPVT 1980 Query: 496 AYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHA 555 + P V + A++P +T V T +P+ +T D+ Sbjct: 1981 PADMVVVPVIPADGPVIPV----TPAESPAIPVTPTDSPVVPVTSADSPVIPVTADSPFV 2036 Query: 556 RHIQGIQPA----PISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQ 611 P P + PI P + P L + S TP N+ P+ Sbjct: 2037 PVTPADSPVIPVTPPDDLVVPVTPIDCP-VVPVTLVDCPVVSVTPANS------PVDPVT 2089 Query: 612 PQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQ-GSSPRPSI 670 P +G V AD I P + A +++ + + + S P SP S+ Sbjct: 2090 PA-DGPVVPVTPADSPVIPVTPADDLIVPVTPADSLIVSVTPADSPVVPVTPADSPVISV 2148 Query: 671 LRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIP--TMI 728 P + V PVT + D P I V P P P + + Sbjct: 2149 ASADSPVVPVTPADTVVV----PVTPA---------DGPVIPVTPAESPAIPVTPADSPV 2195 Query: 729 AAASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEV 788 +P P V ++ + PP + P+ T G ++S GP VP + Sbjct: 2196 VPVTPADDPVVPVTPADSPIVPVPPASDPVVPVTPADTPGSPVASADGPVVPVTSADSPL 2255 Query: 789 EPM 791 P+ Sbjct: 2256 VPV 2258 Score = 64.3 bits (155), Expect = 6e-10 Identities = 171/788 (21%), Positives = 274/788 (34%), Gaps = 120/788 (15%) Query: 113 VASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQV 172 V SA V PA P VP++ ++ P P P+ PA +S+ P + Sbjct: 1309 VTSADSPVVPVTPAD-GPVVPVTSADSPFVPVTPADDPIVPVTPADSPIVSVTPAESPAI 1367 Query: 173 TVTMESS--IPQASA----IPVATISGQ------------QGHPSNLHHIMTTNVQMSII 214 VT S +P SA IP+ T + P++ T+ ++ Sbjct: 1368 PVTPADSPVVPVTSADSPLIPLTTAGSRVVPVTPTGDPIVPVTPADTPGSPVTSADGPVV 1427 Query: 215 RSNAPGPPL-HIGASHLPRGAAAAAVMSSSKVTT--------------VLRPTSQLPNAA 259 G P+ + + P +A VTT V+ TS Sbjct: 1428 PVTPAGDPIVPVTPADTPGSPVTSADGPVVPVTTPDGPLVPVSPPDGPVVPVTSADGPVV 1487 Query: 260 TAQPAVQHIIHQPIQSRP--PVTTSNA----IPPAVVATVSATRAQSPVITTTAAHA--- 310 PA I P PVT +++ + PA + V T A PVI T+A Sbjct: 1488 PVTPADSPFIPVTTADDPIVPVTPADSPVVPVTPADIPVVPVTPANGPVIHVTSADCPFV 1547 Query: 311 ----TDS--ALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMA 364 D AL T + P S + P + D +T+ P + T A Sbjct: 1548 PVIPADGLVALDSSTDVLVVPVSPTDGVLVPDLADDPVVSVTIADSPVIPV------TPA 1601 Query: 365 QKTIFSTGTPVAAATVAPILATN--TIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATA 422 T+ +A V P+ + + +P G V+ P V P+ S Sbjct: 1602 DSTV--VPVTLADGPVVPVTSVDIPVVPVTPANGPVAPV-TPVDDPVVSVNPADGS-VVP 1657 Query: 423 VTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVP 482 VT+++ PV V P + P PA+ S ++P++ + +PV + T +D+ P +P Sbjct: 1658 VTSADCPVVPVTP-----ADGLVVPVTPAD-SPIVPVT---PADSPVVLVTSADS-PVIP 1707 Query: 483 VQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPV-SAQAPNSAITAQTGVGVASTVH 541 V P+ P+ P+TS+ + PV SA P +T+ + V T Sbjct: 1708 V---------TPADSPV-----VPVTSADTDSPGSPVTSADGPVVPVTSADSLPVPVTPA 1753 Query: 542 LNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQG 601 P+ +T AP+S+ P+ TP P T P+ Sbjct: 1754 DGPVVPVTSADGPV--------APVSSADGPVVPV-TPADSPVVPVTTADDPTVPVTPAD 1804 Query: 602 LQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPA 661 P+ P G V AD + P + +V S + P Sbjct: 1805 SPVVPV----PPANGPIVPVTSADSPFVPVIPADGLVVLDSSTDVLVVPVSPTDGILVPD 1860 Query: 662 QGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETVSNQNN--------DQPTIAV 713 P S+ P ++ V + TP + V++ +N D P I V Sbjct: 1861 LADDPVVSVTIADSPVIPVTP-ADSPVVLVTPADGPVVPVTSVDNPVVPVTPADNPVIPV 1919 Query: 714 PPTAQQPPPTIPT--MIAAASPPSQPAVALSTIPGAV-PITP---PITTIAAAPPPSVTV 767 P P P I + P V+++ V P+TP P+ +A+A P V V Sbjct: 1920 TPVDDPVVPVTPADDPIVPVTSADSPIVSVTPADSPVFPVTPADSPVIPVASADSPLVPV 1979 Query: 768 GGS---LSSVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTS 824 + + V+ P I V P + P + T+ SP + + A++ +P + Sbjct: 1980 TPADMVVVPVIPADGPVIPVTPAESPAIPVTPTDSPVVPVTSADSPVIPVTADSPFVPVT 2039 Query: 825 DLPPGASP 832 P SP Sbjct: 2040 ---PADSP 2044 Score = 63.5 bits (153), Expect = 1e-09 Identities = 186/874 (21%), Positives = 299/874 (34%), Gaps = 131/874 (14%) Query: 37 APSTGLSQAPSQIANSGSAGLINPAATVNDESGRDSEVSAREHMSSSSSLQSREEKQEPV 96 +P ++ A S + SA +P + V G V++ + + PV Sbjct: 1703 SPVIPVTPADSPVVPVTSADTDSPGSPVTSADGPVVPVTSADSL--------------PV 1748 Query: 97 VVRPY--PQVQMLSTHHAVA---SATPVAVTAPPAHLTPAVPLSFSEGLMKP------PP 145 V P P V + S VA SA V PA +P VP++ ++ P P Sbjct: 1749 PVTPADGPVVPVTSADGPVAPVSSADGPVVPVTPAD-SPVVPVTTADDPTVPVTPADSPV 1807 Query: 146 KPTMPSR-PIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHI 204 P P+ PI P + P +P V ++SS +PV+ G L Sbjct: 1808 VPVPPANGPIVPVTSADSPFVPVIPADGLVVLDSST-DVLVVPVSPTDGI------LVPD 1860 Query: 205 MTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPA 264 + + +S+ +++P P+ A + V+ + V+ TS PA Sbjct: 1861 LADDPVVSVTIADSPVIPV--------TPADSPVVLVTPADGPVVPVTSVDNPVVPVTPA 1912 Query: 265 VQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQH 324 +I P V + A P V T A SP+++ T A + ++ P S Sbjct: 1913 DNPVIPVTPVDDPVVPVTPADDPIV----PVTSADSPIVSVTPADSPVFPVT-PADSPVI 1967 Query: 325 PPSAAISIQRPAQSRDVTTRITLPSH-PALGTPKQQLHTMAQKTIFSTGTPVAAAT--VA 381 P ++A S P D+ +P+ P + + + S PV +A V Sbjct: 1968 PVASADSPLVPVTPADMVVVPVIPADGPVIPVTPAESPAIPVTPTDSPVVPVTSADSPVI 2027 Query: 382 PILATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHT 441 P+ A + T A S P +V P VT + PV V P Sbjct: 2028 PVTADSPFVPVTPADSPVIPVTPPDDLVVPVTPIDCP-VVPVTLVDCPVVSVTPAN---- 2082 Query: 442 SPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAA 501 SP + P PA+ ++P++ + +PV T +D+ + + P+ P+ Sbjct: 2083 SP-VDPVTPAD-GPVVPVT---PADSPVIPVTPADDLIVPVTPADSLIVSVTPADSPVVP 2137 Query: 502 HTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHI--- 558 TP S V ++ SA +P +T V V T P+ +T S A + Sbjct: 2138 --VTPADSPVISV----ASADSPVVPVTPADTVVVPVTPADGPVIPVTPAESPAIPVTPA 2191 Query: 559 -QGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQG---------------- 601 + P + + P I P P + + TP +T G Sbjct: 2192 DSPVVPVTPADDPVVPVTPADSPIVPVPPASDPVVPVTPADTPGSPVASADGPVVPVTSA 2251 Query: 602 ---LQPAPMGTQQPQP--------------EGKTSAVVLADGATIVANPISNP-FSAAPA 643 L P G P +G V LAD P +P F +PA Sbjct: 2252 DSPLVPVTPGDSPVVPVTPADSPVFPVTSADGPVFPVTLADDPVFPVTPADDPIFPVSPA 2311 Query: 644 ATTVVQ-THSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMET-- 700 + VV T + P S P P + + +T V V + + Sbjct: 2312 DSPVVPVTPANIPVVPVPPANGSVVPVTSAGSPFVPIIPADGLVVLDSSTDVLVVLVSPT 2371 Query: 701 -------------VSNQNNDQPTIAVPPTAQQPPPTIPT--MIAAASPPSQPAVALSTIP 745 VS +D P I V PT P P + + P V ++ Sbjct: 2372 DGIPVPDLADDPVVSVTTSDSPVIPVTPTDSPVVPVAPADGPVVPVTSVDSPVVPVTPAD 2431 Query: 746 G-AVPITPPITTIAAAPP---PSVTV---GGSLSSVLGPPVPEIKVKEEVEPMDIMRPVS 798 +P+TP + + A P P V+V G + V +P I V P+ + P Sbjct: 2432 SPVIPVTPADSLVVPATPADDPVVSVTPADGPVVPVTTADIPVISVTSADSPVVPVTPAD 2491 Query: 799 AVPPLATNTVSPSLALLANNLSMPTSDLPPGASP 832 + + T + S+ + A P + P SP Sbjct: 2492 GL--VVPVTSADSVVVPATPADCPLVPVDPADSP 2523 Score = 59.7 bits (143), Expect = 1e-08 Identities = 163/738 (22%), Positives = 252/738 (34%), Gaps = 119/738 (16%) Query: 112 AVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQ 171 A+ + PV P +P VP++ ++G + P P+ PA +S+ P Sbjct: 360 AIPADGPVVPVTPAD--SPVVPVTPADGPVVSVASADSPFVPVTPADDPIVSVTPADSPV 417 Query: 172 VTVTMESSIPQASAIPVATISGQ------QGHPSNLHHIMTTNVQMSIIRSNAPGPPLHI 225 V VT S IPV T G+ G P + + + S + S A GP + + Sbjct: 418 VPVTSADS----PLIPVTTADGRVVPVTAAGDP--IVPVTPADTPGSPVTS-ADGPVVPV 470 Query: 226 GASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNA----ATAQPAVQHIIHQPIQSRPPVTT 281 ++ +P VT+ P + + +A PA I PVTT Sbjct: 471 TSADIPLVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTPADSPFI--------PVTT 522 Query: 282 SN----AIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQ 337 ++ + PA +S T A+SP I T A DS + P P S P Sbjct: 523 ADDLIVPVTPADSPVLSVTPAESPAIPVTPA---DSPIV-PVTPANGPVVPVTSADSPFV 578 Query: 338 SRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGS 397 +P PA + +PV + T+A A P+ + Sbjct: 579 PVIPADGPVVPVTPA---------DSPVVPVTPADSPVLSVTLADSPAVPVTPADSPVVP 629 Query: 398 VSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLI 457 V+ P + V S S VT ++ P+ V P + S I Sbjct: 630 VTPADGP-----VVPVASADSPFVPVTPADDPIVSVTPAE----------------SPAI 668 Query: 458 PISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQY 517 P++ + +PV T +D RP +PV A P+T++ I Sbjct: 669 PVT---QADSPVVPVTSAD-RPVIPV--------------TTADGRIVPVTAAGDPI--V 708 Query: 518 PVS-AQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQ--PAPISTQGIQPA 574 PV+ A P S +T+ G V T +P +T + AP+S+ Sbjct: 709 PVTPADTPGSPVTSADGPVVPVTSADSPFVPVTPPDGPVVPVTSADGPVAPVSSADGPVV 768 Query: 575 PIGTPGIQPAPLGTQG--IHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVAN 632 P+ + AP+ + + TP +T G PA T P V+ AD + Sbjct: 769 PVTSADGPVAPVSSADGPVVPVTPADTNG--PAVPVTSADSP---FVPVIPADSPVVPVT 823 Query: 633 PISNPF-SAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMA 691 P +P PA ++ V S ++P P + +TD + Sbjct: 824 PADDPIVPVTPADSSFVPV----ISADSPFVPVIPADGPVVVDSSTDVLVVPVFPVNCIL 879 Query: 692 TPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPT------------MIAAASPPSQPAV 739 P V D P I V P P PT + +P PA Sbjct: 880 VPAFADETVVPLNPADSPVIPVTPPDDLVVPVTPTDCPVAPVTSADCPVVPVTPADSPAD 939 Query: 740 ALSTIPG-AVPITP---PITTIAAAPPPSVTV---GGSLSSVLGPPVPEIKVKEEVEPMD 792 ++ G VP TP PI + A P V+V G + V P + V +P+ Sbjct: 940 PVTAADGPVVPFTPADDPIVPVTPADSPVVSVTPADGPVVPVASADSPFVPVTPADDPIV 999 Query: 793 IMRPVSAVPPLATNTVSP 810 + P + T SP Sbjct: 1000 SVTPAESPAIPVTQADSP 1017 Score = 55.8 bits (133), Expect = 2e-07 Identities = 159/696 (22%), Positives = 249/696 (35%), Gaps = 105/696 (15%) Query: 113 VASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQV 172 V SA V PA P VP++ + G + P P P+A A + + P Sbjct: 111 VTSADDPVVPITPAD-NPVVPVTSANGPVIPVTPADSPVFPVASADGPVVPVTPADSPVF 169 Query: 173 TVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPR 232 VT P S + T + P +T +I + A GP +H+ ++ Sbjct: 170 PVT-----PADSPLFPVTPADSPLFP------VTPADSAAIPVTPADGPVVHVTPAN--- 215 Query: 233 GAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVAT 292 G + S V TV S + PA I+ PVT +++ + V Sbjct: 216 GTVVPVTPADSPVVTVASTDSPV---VPVTPADDPIV--------PVTPADS---SFVPV 261 Query: 293 VSATRAQSPVITTTAAHATDSALS------RPTLSIQHPPSAAISIQRPAQSRDVTTRIT 346 +SA PVI DS+ P I P A +I + +T Sbjct: 262 ISADSPFVPVIPADGPVVVDSSTDVLVVPVFPVNCILVPAFADETIXXXXXXXSLVVSVT 321 Query: 347 LPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNT--IPSATTAGSVSHTQAP 404 P + T A + S +A + V P+ ++ +P+ G V Sbjct: 322 TADDPIVPV------TPADSPVLS--VTLADSPVVPVTPADSPFVPAIPADGPVVPVTPA 373 Query: 405 TSTIVTMT--------VPSHSSHATAVTTSNIPVAKVVPQQ-----ITHTSPRIQPDYPA 451 S +V +T V S S VT ++ P+ V P +T + P A Sbjct: 374 DSPVVPVTPADGPVVSVASADSPFVPVTPADDPIVSVTPADSPVVPVTSADSPLIPVTTA 433 Query: 452 ERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSV 511 + ++P++ A+ +P+ T +D P PV P P ++ + TP V Sbjct: 434 D-GRVVPVT---AAGDPIVPVTPADT-PGSPVT-SADGPVVPVTSADIPLVPVTPPDGPV 487 Query: 512 STIRQYPVSAQAPNSAITAQTGVGVASTVHLNP-MQLMTVDASHARHIQGIQPAPISTQG 570 + SA P + +++ G V T +P + + T D I + PA Sbjct: 488 VPV----TSADGPVAPVSSADGPVVPVTPADSPFIPVTTADDL----IVPVTPADSPVLS 539 Query: 571 IQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIV 630 + PA +P I P + I TP N P T P V+ ADG + Sbjct: 540 VTPAE--SPAIPVTPADSP-IVPVTPAN----GPVVPVTSADSP---FVPVIPADGPVVP 589 Query: 631 ANPISNP-FSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVS 689 P +P PA + V+ ++PA +P S + DG S Sbjct: 590 VTPADSPVVPVTPADSPVLSV----TLADSPAVPVTPADSPVVPVTPADGPVVPVASADS 645 Query: 690 MATPVTVSME-TVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPG-A 747 PVT + + VS + P I P Q P +P A +P + ++T G Sbjct: 646 PFVPVTPADDPIVSVTPAESPAI---PVTQADSPVVPVTSA-----DRPVIPVTTADGRI 697 Query: 748 VPIT---PPITTIAAAPPPSVTVGGSLSSVLGPPVP 780 VP+T PI + P+ T G ++S GP VP Sbjct: 698 VPVTAAGDPIVPVT----PADTPGSPVTSADGPVVP 729 Score = 53.9 bits (128), Expect = 8e-07 Identities = 164/712 (23%), Positives = 252/712 (35%), Gaps = 110/712 (15%) Query: 112 AVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQ 171 +VASA V PA T VP++ ++G + P P+ P+ PA + + P Sbjct: 2147 SVASADSPVVPVTPAD-TVVVPVTPADGPVIPVTPAESPAIPVTPADSPVVPVTPADDPV 2205 Query: 172 VTVTMESS----IPQAS--AIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHI 225 V VT S +P AS +PV T + G P ++A GP + + Sbjct: 2206 VPVTPADSPIVPVPPASDPVVPV-TPADTPGSPV----------------ASADGPVVPV 2248 Query: 226 GASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSN-- 283 ++ P S V V S + +A V PVT ++ Sbjct: 2249 TSADSP---LVPVTPGDSPVVPVTPADSPVFPVTSADGPVF-----------PVTLADDP 2294 Query: 284 --AIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDV 341 + PA + A SPV+ T A+ P + + PP+ + + Sbjct: 2295 VFPVTPADDPIFPVSPADSPVVPVTPANI-------PVVPV--PPANGSVVPVTSAGSPF 2345 Query: 342 TTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHT 401 I L + L + T G PV P LA + + S TT+ S Sbjct: 2346 VPIIPADGLVVLDSSTDVLVVLVSPT---DGIPV------PDLADDPVVSVTTSDSPVIP 2396 Query: 402 QAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISG 461 PT + V P+ VT+ + PV V P SP I P PA+ S ++P + Sbjct: 2397 VTPTDSPVVPVAPADGP-VVPVTSVDSPVVPVTPAD----SPVI-PVTPAD-SLVVPAT- 2448 Query: 462 HRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSA-YPLAAHT-----YTPITSSVSTIR 515 + +PV T +D P VPV SA P+ T P+TS+ S + Sbjct: 2449 --PADDPVVSVTPADG-PVVPVTTADIPVISVTSADSPVVPVTPADGLVVPVTSADSVVV 2505 Query: 516 QYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPA--PISTQGIQP 573 A P + V T + NP+ +T D S + + P++ G+ Sbjct: 2506 P-ATPADCPLVPVDPADSPIVLFTPYDNPVVSVTSDDSPVFPVTPADSSVVPVTPAGVPV 2564 Query: 574 APIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANP 633 P+ TPG P T P+ + P+ T P S AD + P Sbjct: 2565 VPV-TPGDGPVVPVTPADSLVVPVTSADSPVFPV-TPADSPVFPVSP---ADDLVVPVTP 2619 Query: 634 ISNPF-SAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMAT 692 +P +PA + VV PA G ++ PA P + Sbjct: 2620 GDSPVVPVSPADSPVVLV--------TPADGP-----VVPVTPANGPVVPVTSADSPFVP 2666 Query: 693 PVTVSMETVSNQNNDQPTIAVPPT-AQQPPPTIPTMIAAASPPSQPAVALSTIPGAVPIT 751 + V + + D + V PT P + +P P V ++ PG P+ Sbjct: 2667 VIPADGLVVLDSSTDVLVVPVFPTDGILVPDLADDPVVPVTPGDDPVVPVT--PGDDPVI 2724 Query: 752 PPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIM-RPVSAVPP 802 P +T P VT +GP VP++ + V P + PV +V P Sbjct: 2725 P-VTPADDGPFVPVT------PAVGPVVPDLTADDSVVPDSLTDDPVISVCP 2769 Score = 53.9 bits (128), Expect = 8e-07 Identities = 173/799 (21%), Positives = 276/799 (34%), Gaps = 168/799 (21%) Query: 95 PVVVRPYPQVQMLSTHHAVASATP---VAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPS 151 P +R +P V ST V ++TP + V PA VP++ G + P P Sbjct: 2868 PDPIRAFPVVPKPSTFSPVVTSTPADWIDVIVTPADCAD-VPVNPVNGPVVPDLSGDCPV 2926 Query: 152 RPIAPAPPSTLSLPPKVPGQVTVTMESSIPQAS-------AIPVATISGQQGHP--SNLH 202 P+ P + PP V V T + P + +PV +G S Sbjct: 2927 VPVPPTDDIVVLNPPDVVFAVVSTPVTDGPVVTDPATDGLMVPVTPANGSVAPVTLSEYP 2986 Query: 203 HIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQ 262 + T +++ GP + P +A ++V+S+ ++ +PN A Sbjct: 2987 DVTVTPADGTVVSPTIGGPVV-------PDPSADSSVVSNPTTDGLI-----VPNPLLAG 3034 Query: 263 PAVQHIIHQPIQSRPPVTTSNAIPPAVVAT---VSATRAQSPVIT--TTAAH------AT 311 P V P T + P ++A V+ T A PV+ TT A Sbjct: 3035 PVV-----------PVTPTDGPLAPVILADCPDVTVTPADGPVVCAFTTGGPVFPDPTAE 3083 Query: 312 DSALSRPTLS---IQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTM----- 363 +S PT+ + +P + + PA DV P PA P ++ + Sbjct: 3084 GLVVSNPTVDDPVVTNPSTKGLVSATPADCADV------PVIPA-DCPDVLVNLVNDSVV 3136 Query: 364 ----AQKTIFSTGTP----------VAAATVAPILATNTIPSATTAG---SVSHTQAPTS 406 A T+ S P + PI +P TT G SV+ AP Sbjct: 3137 PDFTADWTVVSVSPPDDLVAPDPPDEVPVVLVPITDGPVVPDLTTDGLVVSVTPAGAPVV 3196 Query: 407 TI-------VTMT------VPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAER 453 + VT+T VP SS V S + +VP +T + PD PA Sbjct: 3197 PVFLTDCPDVTVTPADSPVVPDPSSDGPVVADS-LDDDGLVP--VTPADDSVVPDSPAN- 3252 Query: 454 SSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVST 513 ++P + PVA + D P VPV P+ P + T Sbjct: 3253 GLVVP---DPTTDGPVAPDPSVDG-PVVPVT---------PADAPTVSVTL--------- 3290 Query: 514 IRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQP 573 A P+ +T G+ V+ + P+ S + PA S + P Sbjct: 3291 -------ADCPDVTVTPPDGLVVSDSKRGGPV---VTGLSTNDPVITATPADFSDVTVTP 3340 Query: 574 APIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLA--DGATIVA 631 A + PA ++ +P+ + + P + VVL D +V Sbjct: 3341 ADFEDVPVTPANCPDVPVNPESPVVSDLAVDFLVVPVVPSDD----LVVLEPPDKVPVVP 3396 Query: 632 NPISNPFSAAPAATTVVQTHSQSASTN----APAQGSSPRPSI-----LRKKPATDGAKP 682 +PISN + T S + +PA G ++ + PA D Sbjct: 3397 DPISNGLVVSDPITNNTAATDPSVDGSVVPVSPADGPVAPVTLADCPDVTITPADDSVVS 3456 Query: 683 KSEIHVSMA-TPVTV-----------SMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAA 730 S+I PVT+ S VS+ D P + +PP P + A Sbjct: 3457 DSKIRAEFEDVPVTIADCPNVPVNPKSGPVVSDLAVDCPVVPIPP---------PDDLVA 3507 Query: 731 ASPPSQPAVALSTIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEP 790 PP + V I ++ ++ P+T A PS + G + V+ P + V + V Sbjct: 3508 PEPPDEVPVVPDPITDSLVVSDPMTDGPVASDPS--IDGIVVPVVSP--SGLLVLDSVAD 3563 Query: 791 MDIMRPVSAVPPLATNTVS 809 + I+ SA P+ T++ Sbjct: 3564 VSILPDTSADVPVTPVTLA 3582 Score = 40.4 bits (93), Expect = 0.009 Identities = 171/800 (21%), Positives = 274/800 (34%), Gaps = 129/800 (16%) Query: 100 PYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPP 159 P P + S +PV P +P VP++ ++G + P T P+ P P Sbjct: 2375 PVPDLADDPVVSVTTSDSPVIPVTPTD--SPVVPVAPADGPVVP---VTSVDSPVVPVTP 2429 Query: 160 STLSLPPKVPGQVTVTMESSIPQASA-IPVATISGQQGHPSNLHHIMTTNVQ-MSIIRSN 217 + + P P V +P A PV +++ G + + T ++ +S+ ++ Sbjct: 2430 ADSPVIPVTPADSLV-----VPATPADDPVVSVTPADG---PVVPVTTADIPVISVTSAD 2481 Query: 218 APGPPL-HIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATA-QPAVQHIIHQPIQS 275 +P P+ +P +A + V+ ++ L P + P ++ Sbjct: 2482 SPVVPVTPADGLVVPVTSADSVVVPATPADCPLVPVDPADSPIVLFTPYDNPVVSVTSDD 2541 Query: 276 RP--PVTTSNA----IPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSAA 329 P PVT +++ + PA V V T PV+ T A +L P S P Sbjct: 2542 SPVFPVTPADSSVVPVTPAGVPVVPVTPGDGPVVPVTPA----DSLVVPVTSADSPVFPV 2597 Query: 330 ISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTI 389 P + +P P +P + + T V P A + Sbjct: 2598 TPADSPVFPVSPADDLVVPVTPG-DSPVVPVSPADSPVVLVTPADGPVVPVTP--ANGPV 2654 Query: 390 PSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDY 449 T+A S P +V + + T I V + + +P P Sbjct: 2655 VPVTSADSPFVPVIPADGLVVLDSSTDVLVVPVFPTDGILVPDLADDPVVPVTPGDDP-- 2712 Query: 450 PAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAH------- 502 ++P++ +PV T +D+ P VPV P P L A Sbjct: 2713 ------VVPVT---PGDDPVIPVTPADDGPFVPV-----TPAVGPVVPDLTADDSVVPDS 2758 Query: 503 -TYTPITSSV--------STIRQ--------YPVSAQAPNSAITAQTGVGVAST---VHL 542 T P+ S T+R YPV+ + V V T V L Sbjct: 2759 LTDDPVISVCPDDGLVVPDTVRDSDGPEVSVYPVTGPVVTDSAADCPVVSVPLTDGLVVL 2818 Query: 543 NPMQLMTVDASHARHIQG-IQPAPISTQGIQPAP-IGTPGIQPAPLGTQGIHS---ATPI 597 P V A H G + P P+ + P + P + A G+ A P+ Sbjct: 2819 CPPD--EVPAVHDSVTNGLVVPDPVIDGPVFSNPSVDGPIVPVASADNPGVPDPIRAFPV 2876 Query: 598 NTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPF---SAAPAATTVVQTHSQS 654 + +P+ T P + V AD A + NP++ P + V Sbjct: 2877 VPKPSTFSPVVTSTP-ADWIDVIVTPADCADVPVNPVNGPVVPDLSGDCPVVPVPPTDDI 2935 Query: 655 ASTNAP----AQGSSP-RPSILRKKPATDGAK-PKSEIHVSMATPVTVSMETVSNQNNDQ 708 N P A S+P + PATDG P + + S+A PVT+S + Sbjct: 2936 VVLNPPDVVFAVVSTPVTDGPVVTDPATDGLMVPVTPANGSVA-PVTLS---------EY 2985 Query: 709 PTIAVPP---TAQQPP---PTIPTMIAAASPPSQPAVALSTIPG------AVPITP---P 753 P + V P T P P +P A +S S P +P VP+TP P Sbjct: 2986 PDVTVTPADGTVVSPTIGGPVVPDPSADSSVVSNPTTDGLIVPNPLLAGPVVPVTPTDGP 3045 Query: 754 ITTIAAAPPPSVTVGGSLSSVL------GPPVPEIKVKEEVEPMDIMRPVSAVPPLATNT 807 + + A P VTV + V+ GP P+ E + + P + P+ TN Sbjct: 3046 LAPVILADCPDVTVTPADGPVVCAFTTGGPVFPD----PTAEGLVVSNP-TVDDPVVTN- 3099 Query: 808 VSPSLALLANNLSMPTSDLP 827 PS L + +D+P Sbjct: 3100 --PSTKGLVSATPADCADVP 3117 >gi|239752529 PREDICTED: similar to mucin [Homo sapiens] Length = 594 Score = 69.3 bits (168), Expect = 2e-11 Identities = 111/489 (22%), Positives = 172/489 (35%), Gaps = 77/489 (15%) Query: 71 DSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVTAPPAHLTP 130 DS + ++S+ + P+ ++ +T H+ S T + T L+P Sbjct: 28 DSTSHSNPSLTSAITTTETRSHSPPIFTSSITTIE--TTSHSTPSFTSLMTTTETTSLSP 85 Query: 131 -AVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQASAIPVA 189 A S S P+ S PS PP +T T +S S V Sbjct: 86 PAFTFSISTTETNSHSPPSFTSSIATTETPS--HSPPSFTSLITTTESTSHSPLSFTSVI 143 Query: 190 TISGQQGH--PSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTT 247 T + H PS I TT SH P +S +TT Sbjct: 144 TTTESTSHSTPSFTSSIATTET-----------------TSHTPPSF-------TSLITT 179 Query: 248 VLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTT------SNAIPPAVVATVSATRAQSP 301 P+ P+ + A + H P + T S I +++AT +T +P Sbjct: 180 TETPSHSNPSFTSLITATESTSHSPPSFTSAIATTGITSHSTPIFTSLIATTDSTSHSTP 239 Query: 302 VITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQQLH 361 T++ + S P+ S + S P+ + +TT T S P+L + Sbjct: 240 SFTSSITSTETISHSTPSFSSLITATKTTSHSTPSLTSLITTTNTSHSTPSLTSLVTSTE 299 Query: 362 TMAQKTIFSTGTPVAAATVAPILAT-----NTIPSATTAGSVSHTQAPTSTIVTMTVPSH 416 T S TP + + I AT + S TT G+ SH+ P+ T +T T+ Sbjct: 300 TA------SHSTPSFTSLITTIEATSHSTPSLTSSITTTGTTSHS-TPSFTYLT-TITES 351 Query: 417 SSHATAVTTSNIPVAKVVPQQITHTSPR-IQPDYPAERSSLIPISGHRASPNPVAMETRS 475 +SH+T TS I + + I +P I P P+ S + ET S Sbjct: 352 TSHSTPSLTSAITTTETMSHSILGFTPSIISPSTPSYISLI------------ATTETPS 399 Query: 476 DNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVG 535 + PS P + A+H+ +TS++ST S S IT Sbjct: 400 HSTPSFPSSI---------TTTQSASHSTPSLTSAISTTEAMSHSIPVFTSLITT----- 445 Query: 536 VASTVHLNP 544 +T HL P Sbjct: 446 TETTSHLPP 454 Score = 50.8 bits (120), Expect = 7e-06 Identities = 76/328 (23%), Positives = 120/328 (36%), Gaps = 39/328 (11%) Query: 108 STHHAVASATPVAVTAPPAHLTPAVP--LSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLP 165 +T H+ S T + T +H TP++ ++ +E P T I ST SL Sbjct: 267 TTSHSTPSLTSLITTTNTSHSTPSLTSLVTSTETASHSTPSFTSLITTIEATSHSTPSLT 326 Query: 166 PKVPGQVTVTMESSIPQASAIPVATISGQQGHPSNLHHIMTTNVQM--------SIIRSN 217 + T T S P + + T S PS I TT SII + Sbjct: 327 SSIT--TTGTTSHSTPSFTYLTTITESTSHSTPSLTSAITTTETMSHSILGFTPSIISPS 384 Query: 218 APGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRP 277 P I + P + + S + + T L +A + A+ H I Sbjct: 385 TPSYISLIATTETPSHSTPSFPSSITTTQSASHSTPSLTSAISTTEAMSHSIPVFTSLIT 444 Query: 278 PVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHP-PSAAISIQRPA 336 T++ +PP + ++ T+ TT+ + + +AL T + H PS SI Sbjct: 445 TTETTSHLPPRFTSLITTTK------TTSHSPPSFTALITSTKTTSHSTPSFTSSI---- 494 Query: 337 QSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPS----- 391 TT T S P+ + T S TP ++++A T+T P Sbjct: 495 ----ATTETTSHSPPSFTSSSTTTET------HSHSTPGFSSSIATSKTTSTSPPRFTFA 544 Query: 392 -ATTAGSVSHTQAPTSTIVTMTVPSHSS 418 ATT ++ T T I + SHS+ Sbjct: 545 IATTKTTLHSTPRFTLAIASTKTTSHST 572 Score = 33.5 bits (75), Expect = 1.1 Identities = 30/136 (22%), Positives = 52/136 (38%), Gaps = 3/136 (2%) Query: 628 TIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIH 687 T +S P +TT +HS + T++ A +P S + S Sbjct: 77 TTETTSLSPPAFTFSISTTETNSHSPPSFTSSIATTETPSHSPPSFTSLITTTESTSHSP 136 Query: 688 VSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQPAVALSTIPGA 747 +S + +T + T + + +IA T PP+ ++I PS + +++ A Sbjct: 137 LSFTSVITTTESTSHSTPSFTSSIATTETTSHTPPSFTSLITTTETPSHSNPSFTSLITA 196 Query: 748 VPIT---PPITTIAAA 760 T PP T A A Sbjct: 197 TESTSHSPPSFTSAIA 212 >gi|56549668 AT rich interactive domain 2 (ARID, RFX-like) [Homo sapiens] Length = 1835 Score = 69.3 bits (168), Expect = 2e-11 Identities = 137/633 (21%), Positives = 216/633 (34%), Gaps = 107/633 (16%) Query: 272 PIQ---SRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTLSIQHPPSA 328 PIQ + PV+TS V + + A SP + + R ++ Q Sbjct: 607 PIQMYYQQQPVSTSVV---RVDSVPDVSPAPSPAGIPHGSQTIGNHFQRTPVANQSSNLT 663 Query: 329 AISIQRPAQSRDVTTRIT--LPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILAT 386 A + P Q + +P +P+ T +QQ A T+ + P+ V + Sbjct: 664 ATQMSFPVQGVHTVAQTVSRIPQNPSPHTHQQQ---NAPVTVIQSKAPIPCEVVKATVIQ 720 Query: 387 NTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQ 446 N+IP S++ P + V V +HS+ VT N P I SP + Sbjct: 721 NSIPQTGVPVSIAVGGGPPQSSV---VQNHSTGPQPVTVVNSQTLLHHPSVIPQQSP-LH 776 Query: 447 PDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTP 506 P + S P++ + + M R N P+ Sbjct: 777 TVVPGQIPSGTPVTVIQQAVPQSHMFGRVQNIPAC------------------------- 811 Query: 507 ITSSVSTIRQYPVSAQAPNSAITAQTGVGVAS--TVHLNPMQLMTVDASHARHIQGIQPA 564 TS+VS +Q ++ P + QT G S TV + P Q +T AS+ +Q Sbjct: 812 -TSTVSQGQQLITTSPQPVQTSSQQTSAGSQSQDTVIIAPPQYVTTSASNIVSATSVQNF 870 Query: 565 PISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLA 624 ++T G G P Q + +G Q I P P+ +QQ Sbjct: 871 QVAT-GQMVTIAGVPSPQASRVGFQNI-----------APKPLPSQQVS----------- 907 Query: 625 DGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDGAKPKS 684 +T+V PI P + +V +Q T APA I+ PA A Sbjct: 908 --STVVQQPIQQPQQPTQQSVVIVSQPAQQGQTYAPA-----IHQIVLANPAALPAGQTV 960 Query: 685 EIHVSMATPVTVSMETVSNQNNDQPTI---AVPPTAQQPPPTIPTMIAAASPPSQPAVAL 741 ++ + S V NN PT + P +Q PPPT+ M++ Q Sbjct: 961 QLTGQPNITPSSSPSPVPATNNQVPTAMSSSSTPQSQGPPPTVSQMLSVKRQQQQ----- 1015 Query: 742 STIPGAVPITPPITTIAAAPPPSVTVGGSLSSVLGPPVPEIKVKEEVEPMDIMRPVSAVP 801 A PP V V V P +++V+ + + +P S Sbjct: 1016 -------------QHSPAPPPQQVQV-----QVQQPQQVQMQVQPQQSNAGVGQPASGES 1057 Query: 802 PLATNTVSPSL--ALLANNLSMPTSDLPPGASPR-KKPRKQQHVISTEEGDMMETNSTDD 858 L + P + L +P +PP + R P+ V S + T Sbjct: 1058 SLIKQLLLPKRGPSTPGGKLILPAPQIPPPNNARAPSPQVVYQVASNQAAGFGVQGQT-- 1115 Query: 859 EKSTAKSLLVKAEKRKSPPKEYIDEEGVRYVPV 891 A+ LLV + + P GV+ VP+ Sbjct: 1116 ---PAQQLLVGQQNVQLVPSAMPPSGGVQTVPI 1145 Score = 53.1 bits (126), Expect = 1e-06 Identities = 120/588 (20%), Positives = 207/588 (35%), Gaps = 101/588 (17%) Query: 144 PPKPTMPSRPIAPAPPSTLSLPPKVPGQVT--VTMESSIPQASAIPVATISGQ------- 194 P P+ + AP + + +P +V +++SIPQ + +PV+ G Sbjct: 685 PQNPSPHTHQQQNAPVTVIQSKAPIPCEVVKATVIQNSIPQ-TGVPVSIAVGGGPPQSSV 743 Query: 195 -QGHPSNLHHIMTTNVQMSIIRSNA--PGPPLH-IGASHLPRGAAAAAVMSSSKVTTVLR 250 Q H + + N Q + + PLH + +P G + + + + Sbjct: 744 VQNHSTGPQPVTVVNSQTLLHHPSVIPQQSPLHTVVPGQIPSGTPVTVIQQAVPQSHMFG 803 Query: 251 PTSQLPNAATAQPAVQHIIH---QPIQSRPPVTTSNA--------IPPAVVAT-----VS 294 +P + Q +I QP+Q+ T++ + PP V T VS Sbjct: 804 RVQNIPACTSTVSQGQQLITTSPQPVQTSSQQTSAGSQSQDTVIIAPPQYVTTSASNIVS 863 Query: 295 ATRAQSPVITT----TAAHATDSALSRPTLSIQHP---PSAAIS---IQRPAQSRDVTTR 344 AT Q+ + T T A SR P PS +S +Q+P Q T+ Sbjct: 864 ATSVQNFQVATGQMVTIAGVPSPQASRVGFQNIAPKPLPSQQVSSTVVQQPIQQPQQPTQ 923 Query: 345 --ITLPSHPALG--TPKQQLHTM---------AQKTIFSTGTP--VAAATVAPILATNT- 388 + + S PA T +H + A +T+ TG P +++ +P+ ATN Sbjct: 924 QSVVIVSQPAQQGQTYAPAIHQIVLANPAALPAGQTVQLTGQPNITPSSSPSPVPATNNQ 983 Query: 389 IPSATTAGSVSHTQAPTSTIVTMTV---PSHSSHATAVTTSNIPVAKVVPQQITHTSPRI 445 +P+A ++ S +Q P T+ M H+ A + V PQQ+ ++ Sbjct: 984 VPTAMSSSSTPQSQGPPPTVSQMLSVKRQQQQQHSPAPPPQQVQVQVQQPQQV---QMQV 1040 Query: 446 QPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYT 505 QP + P SG + + + R + P + P PP Sbjct: 1041 QPQQ-SNAGVGQPASGESSLIKQLLLPKRGPSTPGGKLILP--APQIPP----------- 1086 Query: 506 PITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLN---PMQLMTVDASHARHIQGIQ 562 P +A+AP+ + Q A+ + P Q + V + + + Sbjct: 1087 ------------PNNARAPSPQVVYQVASNQAAGFGVQGQTPAQQLLVGQQNVQLVPSAM 1134 Query: 563 PAPISTQGIQPAPIGTPGIQPAPLGTQG---IHSATPINTQGLQPAPMGTQQPQ--PEGK 617 P + G+Q PI I P PL + I T N + P + P +G Sbjct: 1135 PP---SGGVQTVPISNLQILPGPLISNSPATIFQGTSGNQVTITVVPNTSFAPATVSQGN 1191 Query: 618 TSAVVLADGATI--VANPISNPFSAAPAATTVVQTHSQSASTNAPAQG 663 + ++ G T+ + P PA S + P +G Sbjct: 1192 ATQLIAPAGITMSGTQTGVGLPVQTLPATQASPAGQSSCTTATPPFKG 1239 >gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens] Length = 1486 Score = 68.9 bits (167), Expect = 2e-11 Identities = 167/800 (20%), Positives = 279/800 (34%), Gaps = 107/800 (13%) Query: 59 NPAATVNDESGRDS-EVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASAT 117 +P +TV D + + + S +S+ +SL P +++T ++S Sbjct: 339 SPTSTVTDSTTKIAYSTSMTGTLSTETSLPPTSSSLPTTETATTPMTNLVTTTTEISS-- 396 Query: 118 PVAVTAPPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTME 177 H TP+ S + P S PS + P+ T T Sbjct: 397 ---------HSTPSFSSSTIYSTVTSHSTPRFTSSITTTETPSHST--PRFTSSFTNTKT 445 Query: 178 SSIPQASAIPVATISGQQGH--PSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAA 235 +S S + T + H PS I TT RS SH R Sbjct: 446 TSHRSPSFTSLITTTETTSHSTPSFTSSITTTETTSHSARSFTSSITTTETTSHNTRSFT 505 Query: 236 AAAVMSSSKVTTVLRPTSQLPNAATAQ---PAVQHII---HQPIQSRPPVT-------TS 282 ++ + + + TS + T P+ I P+ S P +T T+ Sbjct: 506 SSITTTETNSHSTTSFTSSITTTETTSHSTPSFSSSITTTETPLHSTPGLTSWVTTTKTT 565 Query: 283 NAIPPAVVATVSATRAQSP---------VITTTAAHATDSALSRPTLSIQHPPSAAISIQ 333 + I P + ++++ T S T T + +T S S S + AI+ Sbjct: 566 SHITPGLTSSITTTETTSHSTPGFTSSITTTETTSESTPSLSSSTIYSTVSTSTTAITSH 625 Query: 334 RPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATN--TIPS 391 VT PS + P L T+ ++ T T + T P + T+ T+P+ Sbjct: 626 FTTSETAVTPTPVTPSSLSTDIPTTSLRTLTPSSV-GTSTSLTTTTDFPSIPTDISTLPT 684 Query: 392 AT--TAGSVSHTQAPTSTIVTMTVPSHSS-HATAVTTSNIPVAK------VVPQQITHTS 442 T + S S TS++V T P+ S+ T T N P++ V+P+ T T Sbjct: 685 RTHIISSSPSIQSTETSSLVGTTSPTMSTVRMTLRITENTPISSFSTSIVVIPETPTQTP 744 Query: 443 PRIQPDYPAERS---SLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSAY-- 497 P + + S + + +S + + T S ++ Q +P+ S Sbjct: 745 PVLTSATGTQTSPAPTTVTFGSTDSSTSTLHTLTPSTALSTIVSTSQVPIPSTHSSTLQT 804 Query: 498 -PLAAHTYTPITS-SVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHA 555 P T +TS S T + + + N+ +T+ + + +ST P +M+ S A Sbjct: 805 TPSTPSLQTSLTSTSEFTTESFTRGSTSTNAILTSFSTIIWSST----PTIIMSSSPSSA 860 Query: 556 R---------HIQGIQPAPISTQGIQPAPI-GTPGIQPAPLG---------TQGIHSATP 596 H P ST+ + A I G P + + T + TP Sbjct: 861 SITPVFSTTIHSVPSSPYIFSTENVGSASITGFPSLSSSATTSTSSTSSSLTTALTEITP 920 Query: 597 ---INTQGLQPAPMG-TQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQ--- 649 I+ P P T P T V D +T +P + P + P T +V Sbjct: 921 FSYISLPSTTPCPGTITITIVPASPTDPCVEMDPSTEATSPPTTPLTVFPFTTEMVTCPT 980 Query: 650 --------THSQSASTNAPAQGSSPRPSILRKKPATDGAKPKSEIHVSMATPVTVSMETV 701 T S+ P SS P+ G P + + S P + + + Sbjct: 981 SISIQTTLTTYMDTSSMMPESESSISPNA--SSSTGTGTVPTNTVFTSTRLPTSETW--L 1036 Query: 702 SNQNN---DQPTIAVPPTAQQPPPTIPTMIAAASP---PSQPAVALSTIPGAVPITPPIT 755 SN + P ++ P +P ++PT++ +S PS P S P A TP T Sbjct: 1037 SNSSVIPLPLPGVSTIPLTMKPSSSLPTILRTSSKSTHPSPPTTRTSETPVATTQTP--T 1094 Query: 756 TIAAAPPPSVTVGGSLSSVL 775 T+ + +T + S L Sbjct: 1095 TLTSRRTTRITSQMTTQSTL 1114 Score = 68.2 bits (165), Expect = 4e-11 Identities = 169/836 (20%), Positives = 301/836 (36%), Gaps = 126/836 (15%) Query: 74 VSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVAVT----------A 123 V++ ++SS + + +P + S + S+TPV T Sbjct: 253 VTSTSPITSSITSTNTVTSMTTTASQPTATNTLSSPTRTILSSTPVLSTETITSGITNTT 312 Query: 124 PPAHLTPAVPLSFSEGLMKPPPKPTMPSRPIAPAPPSTLSLPPKVPGQVTVTMESSIPQA 183 P + L +P + S P + T P+ P + ST + T++ E+S+P Sbjct: 313 PLSTLVTTLPTTISRST--PTSETTYPTSPTSTVTDSTTKIAYSTSMTGTLSTETSLPPT 370 Query: 184 SAIPVATISGQQGHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSS 243 S +++ + + + +++TT ++S + P ++ + + +S Sbjct: 371 S----SSLPTTETATTPMTNLVTTTTEIS-----SHSTPSFSSSTIYSTVTSHSTPRFTS 421 Query: 244 KVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAI---PPAVVATVSATR--- 297 +TT P+ P ++ + H+ +TT+ P+ ++++ T Sbjct: 422 SITTTETPSHSTPRFTSSFTNTKTTSHRSPSFTSLITTTETTSHSTPSFTSSITTTETTS 481 Query: 298 ------AQSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHP 351 S T T +H T S S T + + S S + + T+ T Sbjct: 482 HSARSFTSSITTTETTSHNTRSFTSSITTTETNSHSTT-SFTSSITTTETTSHSTPSFSS 540 Query: 352 ALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSVSHTQAPTSTIVTM 411 ++ T + LH+ T + T T + + ++ T T+ + T + T+T T Sbjct: 541 SITTTETPLHSTPGLTSWVTTTKTTSHITPGLTSSITTTETTSHSTPGFTSSITTTETTS 600 Query: 412 -TVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAERSSLIPISGHRA-SPNPV 469 + PS SS T S A + T+ P P+ S+ IP + R +P+ V Sbjct: 601 ESTPSLSSSTIYSTVSTSTTAITSHFTTSETAVTPTPVTPSSLSTDIPTTSLRTLTPSSV 660 Query: 470 AME---TRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNS 526 T + + PS+P + T P T T I SS +I+ S+ + Sbjct: 661 GTSTSLTTTTDFPSIPTD----ISTLP---------TRTHIISSSPSIQSTETSSLVGTT 707 Query: 527 AITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPL 586 + T T V T+ + T +S + I I P T + + GT PAP Sbjct: 708 SPTMST---VRMTLRITE---NTPISSFSTSIVVIPETPTQTPPVLTSATGTQ-TSPAPT 760 Query: 587 ---------GTQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNP 637 T +H+ TP + L +Q P P +S T+ P + Sbjct: 761 TVTFGSTDSSTSTLHTLTP--STALSTIVSTSQVPIPSTHSS--------TLQTTPSTPS 810 Query: 638 FSAAPAATTVVQTHS---QSASTNAPAQG------SSPRPSILRKKPATDGAKP--KSEI 686 + +T+ T S S STNA SS I+ P++ P + I Sbjct: 811 LQTSLTSTSEFTTESFTRGSTSTNAILTSFSTIIWSSTPTIIMSSSPSSASITPVFSTTI 870 Query: 687 HVSMATPVTVSMETV------------------SNQNNDQPTIAVP----------PTAQ 718 H ++P S E V ++ + T A+ P+ Sbjct: 871 HSVPSSPYIFSTENVGSASITGFPSLSSSATTSTSSTSSSLTTALTEITPFSYISLPSTT 930 Query: 719 QPPPTIPTMIAAASPPSQPAVAL-----STIPGAVPITP-PITTIAAAPPPSVTVGGSLS 772 P TI I AS P+ P V + +T P P+T P TT P S+++ +L+ Sbjct: 931 PCPGTITITIVPAS-PTDPCVEMDPSTEATSPPTTPLTVFPFTTEMVTCPTSISIQTTLT 989 Query: 773 SVLGPPVPEIKVKEEVEPMDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPP 828 + + + + + P + P TNTV S L + + S + P Sbjct: 990 TYMDTSSMMPESESSISPNASSSTGTGTVP--TNTVFTSTRLPTSETWLSNSSVIP 1043 Score = 66.2 bits (160), Expect = 1e-10 Identities = 148/741 (19%), Positives = 254/741 (34%), Gaps = 102/741 (13%) Query: 196 GHPSNLHHIMTTNVQMSIIRSNAPGPPLHIGASHLPRG-----------------AAAAA 238 GH N +TT+ ++I P+ S P A Sbjct: 69 GHRENAPMTLTTSPHDTLISETLLNSPVSSNTSTTPTSKFAFKVETTPPTVLVYSATTEC 128 Query: 239 VMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRA 298 V +S + T+ PTS T Q A ++ PVTT V +T S T Sbjct: 129 VYPTSFIITISHPTSIC--VTTTQVAFTSSYTSTPVTQKPVTT-------VTSTYSMTTT 179 Query: 299 QSPVITTTAAHATDSALSRPTLSIQHPPSAAISIQRPAQSRDVTTRITLPSHPALGTPKQ 358 + T++ +T +A P +++ PS+ + + +T T P P Sbjct: 180 EKGTSAMTSSPSTTTARETPIVTVT--PSSVSATDTTFHTTISSTTRTTERTPL---PTG 234 Query: 359 QLHTMAQKTIFSTGTPVAAATVAPILA----TNTIPSATTAGS----VSHTQAPTSTIVT 410 +HT T T A + +PI + TNT+ S TT S + +PT TI++ Sbjct: 235 SIHTTTSPTPVFTTLKTAVTSTSPITSSITSTNTVTSMTTTASQPTATNTLSSPTRTILS 294 Query: 411 MTVPSHSSHATAVTTSNIPVAKVV---PQQITHTSPRIQPDYPAERSSLIPISGHRASPN 467 T + T+ T+ P++ +V P I+ ++P + YP +S + S + + + Sbjct: 295 STPVLSTETITSGITNTTPLSTLVTTLPTTISRSTPTSETTYPTSPTSTVTDSTTKIAYS 354 Query: 468 PVAMETRSDNRPSVPVQFQYFLPTYPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSA 527 +M S+P PT S+ P TP+T+ V+T + + S+ Sbjct: 355 -TSMTGTLSTETSLP-------PT--SSSLPTTETATTPMTNLVTTTTEISSHSTPSFSS 404 Query: 528 ITAQTGVGVASTVHLNPMQLMTVDASHARHIQGIQPAPISTQGIQPAPIGTPGIQPAPLG 587 T + V ST T SH+ S + +P Sbjct: 405 STIYSTVTSHSTPRFTSSITTTETPSHS-----TPRFTSSFTNTKTTSHRSPSFTSLITT 459 Query: 588 TQGIHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADG--------ATIVANPISNPFS 639 T+ +TP T + T TS++ + + + +N S Sbjct: 460 TETTSHSTPSFTSSITTTE--TTSHSARSFTSSITTTETTSHNTRSFTSSITTTETNSHS 517 Query: 640 AAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPATDG----AKPKSEIHVSMATPVT 695 +++ T + S ST + + + + L P K S I + + +T Sbjct: 518 TTSFTSSITTTETTSHSTPSFSSSITTTETPLHSTPGLTSWVTTTKTTSHITPGLTSSIT 577 Query: 696 VSMETVSNQNNDQPTIAVPPTAQQPPP------------TIPTMIAAASPPSQPAVALST 743 + T + +I T + P T T I + S+ AV + Sbjct: 578 TTETTSHSTPGFTSSITTTETTSESTPSLSSSTIYSTVSTSTTAITSHFTTSETAVTPTP 637 Query: 744 I-PGAVPITPPITTIAAAPPPSVTVGGSLSSVLG-PPVPE-----------IKVKEEVEP 790 + P ++ P T++ P SV SL++ P +P I ++ Sbjct: 638 VTPSSLSTDIPTTSLRTLTPSSVGTSTSLTTTTDFPSIPTDISTLPTRTHIISSSPSIQS 697 Query: 791 MDIMRPVSAVPPLATNTVSPSLALLANN--LSMPTSDLPPGASPRKKPRKQQHVISTEEG 848 + V P +TV +L + N S TS + +P + P T+ Sbjct: 698 TETSSLVGTTSP-TMSTVRMTLRITENTPISSFSTSIVVIPETPTQTPPVLTSATGTQTS 756 Query: 849 DMMET---NSTDDEKSTAKSL 866 T STD ST +L Sbjct: 757 PAPTTVTFGSTDSSTSTLHTL 777 >gi|222352122 hypothetical protein LOC284297 [Homo sapiens] Length = 1573 Score = 68.2 bits (165), Expect = 4e-11 Identities = 132/599 (22%), Positives = 198/599 (33%), Gaps = 97/599 (16%) Query: 220 GPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQSRPPV 279 GP L G + P V + P + P A + A P S P Sbjct: 959 GPTLGAGTTRSPGSPPTLRVHGDTGSPRKPWPERRPPRPAATRTA------PPTPSPGPS 1012 Query: 280 TTSNAIPPAVVATVSATRAQSPVITTTAAHATDSA-LSRPTLSIQHPPSAAISIQRPAQS 338 + PP T ++R +P T+ +D+ S PT + + + P + Sbjct: 1013 ASPG--PPGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFA 1070 Query: 339 RDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAPILATNTIPSATTAGSV 398 +P+ +P L T+ ++ TP +++P + +P + T + Sbjct: 1071 LSTPDSSVVPALTPEPSPTP-LPTLPKELTSDPSTPSEVTSLSP--TSEQVPESDTTPDL 1127 Query: 399 SHTQAPTSTIVT----MTVPSHSSHATAVTTSNIPVAKVVPQQITHTSPRIQPDYPAE-- 452 T P S+ V+ PS S H T P + P IT +P + P +P Sbjct: 1128 DTT--PYSSTVSEYSRSPDPSPSPHPTTT-----PDPTMAPDPITTLNPTVTPHFPTTPH 1180 Query: 453 -----------RSSLIPISGHRASPNPVAMETRSDNRP---SVPVQFQYFLPTYPP-SAY 497 S++IP +P P T S P + P F PT P S Sbjct: 1181 PTTTPHPTTITHSTMIP--DPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTT 1238 Query: 498 PLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVH--LNPMQLMTVDASHA 555 P T P T + ST+ P + P + + T +T H P T + Sbjct: 1239 PHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTTT 1298 Query: 556 RHIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPE 615 H + P P +T P P TP P T S+TP+ T P +GT+ P Sbjct: 1299 PH-PTMTPDPTTT----PYPTTTPDPTTTPHPTTPDPSSTPVITTVSLPTSLGTELSSP- 1352 Query: 616 GKTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKP 675 A T H Q T S+ + L P Sbjct: 1353 -------------------------TLAPTVKPSLHPQLTFTAPAPHTSTSQIPTLEPSP 1387 Query: 676 ATDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPT---------AQQPPPTI-P 725 A + + +S SM +S E + P + PPT P P + P Sbjct: 1388 ALESSPSRSSTATSMDP---LSTEDFKPPRSQSPNLTPPPTHTPHSASDLTVSPDPLLSP 1444 Query: 726 TMIAAASPPSQPAVALSTIPGAVP--------ITPPITTIAAAPPPSVTVGGSLSSVLG 776 T PP P + L PG P TPP+ +A PP V + ++ V G Sbjct: 1445 TAHPLDHPPLDP-LTLGPTPGQSPGPHGPCVAPTPPVRVMACEPPALVELVAAVRDVGG 1502 Score = 67.8 bits (164), Expect = 5e-11 Identities = 133/565 (23%), Positives = 194/565 (34%), Gaps = 95/565 (16%) Query: 144 PPKPTMPSRPIAPAPPSTLSLPPKV-PGQVTVTMESSIPQASAIPVA-TISGQQGHPSNL 201 P KP RP P P +T + PP PG P AS P ++ Sbjct: 985 PRKPWPERRP--PRPAATRTAPPTPSPG----------PSASPGPPGPALTSDSSRELTP 1032 Query: 202 HHIMTTNVQMSIIRSNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATA 261 H +T+ ++ P P P ++ +S + P S + A T Sbjct: 1033 HSALTSEATSDAPDTSPPTPD--------PASRTNPDLILTSPDFALSTPDSSVVPALTP 1084 Query: 262 QPAVQHIIHQPIQSRPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHAT---DSALSRP 318 +P+ P+ + P TS+ P+ V ++S T Q P TT T S +S Sbjct: 1085 EPSPT-----PLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEY 1139 Query: 319 TLSIQHPPSA-AISIQRPAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTI-FSTGTPVA 376 + S PS + P + D T + P T T TI ST P Sbjct: 1140 SRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTTPHPTTITHSTMIPDP 1199 Query: 377 AATVAP---ILATNTIPSATTAGSVSHTQAPTSTIVTMTV-PSHSSHATAVTTSN-IPVA 431 T P I + IP TT T PT+T + T P+ + H T +T S IP Sbjct: 1200 TTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTITHSTMIPDP 1259 Query: 432 KVVPQQITHTSPRIQPDYPAERSSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPT 491 PQ T P P +P +P+P T P Y T Sbjct: 1260 TTTPQPFTTMQPTTMP-HPTTTPHPTTTPHPTTTPHPTT--TPHPTMTPDPTTTPYPTTT 1316 Query: 492 YPPSAYPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVH--LNPMQLMT 549 P+ P H TP SS I + P S T + +A TV L+P T Sbjct: 1317 PDPTTTP---HPTTPDPSSTPVI----TTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFT 1369 Query: 550 VDASHAR--HIQGIQPAP-----------------ISTQGIQPAPIGTPGIQPAPLGTQG 590 A H I ++P+P +ST+ +P +P + P P T Sbjct: 1370 APAPHTSTSQIPTLEPSPALESSPSRSSTATSMDPLSTEDFKPPRSQSPNLTPPPTHTP- 1428 Query: 591 IHSATPINTQGLQPAPMGTQQPQPEGKTSAVVLADGATIVANPISNPFSAAPAATTVVQT 650 HSA+ + T P P +L+ A + +P +P + P T Sbjct: 1429 -HSASDL-----------TVSPDP-------LLSPTAHPLDHPPLDPLTLGP-------T 1462 Query: 651 HSQSASTNAPAQGSSPRPSILRKKP 675 QS + P +P ++ +P Sbjct: 1463 PGQSPGPHGPCVAPTPPVRVMACEP 1487 Score = 54.3 bits (129), Expect = 6e-07 Identities = 111/484 (22%), Positives = 162/484 (33%), Gaps = 95/484 (19%) Query: 385 ATNTIPSATTAGSVSHTQAPTSTIVTMTVPSHSSHA--TAVTTSNIP-VAKVVPQQITHT 441 AT T P + G + P + + + + H+ T+ TS+ P + P + T Sbjct: 999 ATRTAPPTPSPGPSASPGPPGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRT 1058 Query: 442 SPRI---QPDYPAER--SSLIPISGHRASPNPVAMETRSDNRPSVPVQFQYFLPTYPPSA 496 +P + PD+ SS++P SP P+ P++P + T PS Sbjct: 1059 NPDLILTSPDFALSTPDSSVVPALTPEPSPTPL---------PTLPKEL-----TSDPS- 1103 Query: 497 YPLAAHTYTPITSSVSTIRQYPVSAQAPNSAITAQTGVGVASTVHLNPMQLMTVDASHAR 556 T + +TS T Q P S P+ T + STV + Sbjct: 1104 ------TPSEVTSLSPTSEQVPESDTTPDLDTTPYS-----STV--------------SE 1138 Query: 557 HIQGIQPAPISTQGIQPAPIGTPGIQPAPLGTQGIHSATPINTQGLQPAPMGTQQPQPEG 616 + + P+P P P TP AP I + P T P T P P Sbjct: 1139 YSRSPDPSP------SPHPTTTPDPTMAP---DPITTLNPTVTPHFPTTPHPTTTPHPTT 1189 Query: 617 KTSAVVLADGATIVANPISNPFSAAPAATTVVQTHSQSASTNAPAQGSSPRPSILRKKPA 676 T + ++ D T PF TT+ THS T P ++P+P + Sbjct: 1190 ITHSTMIPDPTTT-----PQPF------TTI--THS----TMIPDPTTTPQPFTTMQPTT 1232 Query: 677 TDGAKPKSEIHVSMATPVTVSMETVSNQNNDQPTIAVPPTAQQPPPTIPTMIAAASPPSQ 736 T + T +T S QP + PT P T P P + Sbjct: 1233 TPHSTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTT 1292 Query: 737 PAVALSTIPGAVP---------ITPPITTI--AAAPPPS-------VTVGGSLSSVLGPP 778 P + P P TP TT P PS V++ SL + L P Sbjct: 1293 PHPTTTPHPTMTPDPTTTPYPTTTPDPTTTPHPTTPDPSSTPVITTVSLPTSLGTELSSP 1352 Query: 779 VPEIKVKEEVEP---MDIMRPVSAVPPLATNTVSPSLALLANNLSMPTSDLPPGASPRKK 835 VK + P P ++ + T SP+L + S TS P K Sbjct: 1353 TLAPTVKPSLHPQLTFTAPAPHTSTSQIPTLEPSPALESSPSRSSTATSMDPLSTEDFKP 1412 Query: 836 PRKQ 839 PR Q Sbjct: 1413 PRSQ 1416 Score = 51.2 bits (121), Expect = 5e-06 Identities = 110/497 (22%), Positives = 160/497 (32%), Gaps = 63/497 (12%) Query: 4 PRHPQAGEIEAGGAGGGRRLQVEMSSQQFPRLGAPSTGLSQAPSQIANSGSAGLINPAAT 63 P P G + G G L + S + P S S AP S +PA+ Sbjct: 1004 PPTPSPGPSASPGPPGPA-LTSDSSRELTPHSALTSEATSDAPDT-----SPPTPDPASR 1057 Query: 64 VNDE---SGRDSEVSAREHMSSSSSLQSREEKQEPVVVRPYPQVQMLSTHHAVASATPVA 120 N + + D +S + SS + E P+ P ST V S +P + Sbjct: 1058 TNPDLILTSPDFALSTPD--SSVVPALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTS 1115 Query: 121 VTAPPAHLTP---AVPLS--FSEGLMKPPPKP----------TMPSRPIAPAPPS----- 160 P + TP P S SE P P P TM PI P+ Sbjct: 1116 EQVPESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHF 1175 Query: 161 -TLSLPPKVPGQVTVTMESSIPQASAIP----VATISGQQGHPSNLHHIMTTNVQMSIIR 215 T P P T+T + IP + P T S P+ TT + Sbjct: 1176 PTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPH 1235 Query: 216 SNAPGPPLHIGASHLPRGAAAAAVMSSSKVTTVLRPTSQLPNAATAQPAVQHIIHQPIQS 275 S P P + + ++ + T ++PT+ T P H Sbjct: 1236 STTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTP--HPTTTP 1293 Query: 276 RPPVTTSNAIPPAVVATVSATRAQSPVITTTAAHATDSALSRPTL-SIQHPPSAAISIQR 334 P T + P T T P TTT T S P + ++ P S + Sbjct: 1294 HPTTTPHPTMTPDPTTTPYPTTTPDP--TTTPHPTTPDPSSTPVITTVSLPTSLGTELSS 1351 Query: 335 PAQSRDVTTRITLPSHPALGTPKQQLHTMAQKTIFSTGTPVAAATVAP---ILATNTIPS 391 P + V + HP L HT + T P A +P AT+ P Sbjct: 1352 PTLAPTVKPSL----HPQLTFTAPAPHTSTSQ--IPTLEPSPALESSPSRSSTATSMDPL 1405 Query: 392 ATTAGSVSHTQAPTSTIVTMTVPSHSSH-ATAVTTSNIPVAKVVPQQITHTSPRIQPDYP 450 +T +Q+P T P+H+ H A+ +T S P+ + H P Sbjct: 1406 STEDFKPPRSQSPNLT----PPPTHTPHSASDLTVSPDPLLSPTAHPLDHP--------P 1453 Query: 451 AERSSLIPISGHRASPN 467 + +L P G P+ Sbjct: 1454 LDPLTLGPTPGQSPGPH 1470 Score = 32.3 bits (72), Expect = 2.4 Identities = 56/237 (23%), Positives = 72/237 (30%), Gaps = 40/237 (16%) Query: 100 PYPQVQMLSTHHAVASATPVAVTAPPAHLTPAVPLSFSEGLMKPPPK----------PTM 149 P P M T + TP T P TP P + M P P PT Sbjct: 1263 PQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPH-PTTTPHPTMTPDPTTTPYPTTTPDPTT 1321 Query: 150 PSRPIAPAPPST-----LSLP-----------------PKVPGQVTVTMESSIPQASAIP 187 P P P ST +SLP P + Q+T T + S IP Sbjct: 1322 TPHPTTPDPSSTPVITTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQIP 1381 Query: 188 VATISGQQGHPSNLHHIMTTNVQMSIIRSNAP---GPPLHIGASHLPRGAAAAAVMSSSK 244 S + T+ +S P P L +H P A+ V Sbjct: 1382 TLEPSPALESSPSRSSTATSMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTVSPDPL 1441 Query: 245 VTTVLRPTSQLPNAATA---QPAVQHIIHQP-IQSRPPVTTSNAIPPAVVATVSATR 297 ++ P P P H P + PPV PPA+V V+A R Sbjct: 1442 LSPTAHPLDHPPLDPLTLGPTPGQSPGPHGPCVAPTPPVRVMACEPPALVELVAAVR 1498 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.310 0.124 0.354 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 46,727,311 Number of Sequences: 37866 Number of extensions: 2651103 Number of successful extensions: 26506 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 205 Number of HSP's successfully gapped in prelim test: 1186 Number of HSP's that attempted gapping in prelim test: 13320 Number of HSP's gapped (non-prelim): 7320 length of query: 1048 length of database: 18,247,518 effective HSP length: 113 effective length of query: 935 effective length of database: 13,968,660 effective search space: 13060697100 effective search space used: 13060697100 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.