Guide to the Human Genome
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Search of human proteins with 19923391

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19923391 homeobox D3 [Homo sapiens]
         (432 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19923391 homeobox D3 [Homo sapiens]                                909   0.0  
gi|24497513 homeobox A3 isoform a [Homo sapiens]                      401   e-112
gi|13562112 homeobox A3 isoform a [Homo sapiens]                      401   e-112
gi|84570137 homeobox B3 [Homo sapiens]                                394   e-109
gi|24497515 homeobox A3 isoform b [Homo sapiens]                      315   7e-86
gi|10140847 homeobox A2 [Homo sapiens]                                130   2e-30
gi|4504465 homeobox B2 [Homo sapiens]                                 126   3e-29
gi|23397672 homeobox D4 [Homo sapiens]                                125   7e-29
gi|13273315 homeobox B4 [Homo sapiens]                                121   1e-27
gi|148613882 homeobox A4 [Homo sapiens]                               114   2e-25
gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]          112   7e-25
gi|24497517 homeobox A5 [Homo sapiens]                                112   7e-25
gi|24497538 homeobox C4 [Homo sapiens]                                112   7e-25
gi|24497540 homeobox C4 [Homo sapiens]                                112   7e-25
gi|13375632 homeobox D1 [Homo sapiens]                                110   3e-24
gi|13489077 homeobox A6 [Homo sapiens]                                109   6e-24
gi|4504469 homeobox B5 [Homo sapiens]                                 107   2e-23
gi|24497526 homeobox B1 [Homo sapiens]                                104   1e-22
gi|11321638 homeobox C5 [Homo sapiens]                                103   3e-22
gi|15029506 homeobox D8 [Homo sapiens]                                101   1e-21
gi|24497556 homeobox A7 [Homo sapiens]                                100   3e-21
gi|23503237 homeobox B6 [Homo sapiens]                                 99   6e-21
gi|33457326 GS homeobox 1 [Homo sapiens]                               96   5e-20
gi|85068580 homeobox B7 [Homo sapiens]                                 96   6e-20
gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]                95   1e-19
gi|5031761 homeobox A1 isoform a [Homo sapiens]                        95   1e-19
gi|121114296 caudal type homeobox 1 [Homo sapiens]                     95   1e-19
gi|182765442 homeobox A10 isoform a [Homo sapiens]                     94   2e-19
gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]                  94   2e-19
gi|169636435 caudal type homeobox 2 [Homo sapiens]                     94   3e-19

>gi|19923391 homeobox D3 [Homo sapiens]
          Length = 432

 Score =  909 bits (2350), Expect = 0.0
 Identities = 432/432 (100%), Positives = 432/432 (100%)

Query: 1   MLFEQGQQALELPECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLD 60
           MLFEQGQQALELPECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLD
Sbjct: 1   MLFEQGQQALELPECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLD 60

Query: 61  TDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPP 120
           TDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPP
Sbjct: 61  TDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPP 120

Query: 121 PPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATA 180
           PPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATA
Sbjct: 121 PPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATA 180

Query: 181 GESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI 240
           GESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI
Sbjct: 181 GESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI 240

Query: 241 WFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPP 300
           WFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPP
Sbjct: 241 WFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSPP 300

Query: 301 AFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGG 360
           AFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGG
Sbjct: 301 AFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMASNGGGFASANLQGSPVYVGG 360

Query: 361 NFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQ 420
           NFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQ
Sbjct: 361 NFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSAHHSSQ 420

Query: 421 GRLPEAPKLTHL 432
           GRLPEAPKLTHL
Sbjct: 421 GRLPEAPKLTHL 432


>gi|24497513 homeobox A3 isoform a [Homo sapiens]
          Length = 443

 Score =  401 bits (1030), Expect = e-112
 Identities = 231/455 (50%), Positives = 283/455 (62%), Gaps = 51/455 (11%)

Query: 17  MQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLDTDYPGSACSIQSSAPL 76
           MQKA YY++  ++GGY Y +  + + Y+   QPYP  AA  + D +Y   ACS+QS  P 
Sbjct: 1   MQKATYYDSSAIYGGYPY-QAANGFAYNANQQPYPASAALGA-DGEYHRPACSLQS--PS 56

Query: 77  RAPAH-KGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQ-------------QPPQPPPP 122
            A  H K  EL+ +C+R  +         SQPP L                 QPPQP P 
Sbjct: 57  SAGGHPKAHELSEACLRTLSAPP------SQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQ 110

Query: 123 PPTLPPSSPTNPGGGVPAKKPKGGP---NASSS----SATISKQIFPWMKESRQNSKQKN 175
           PP   P++P  P    P +     P   NA+ S    S T++KQIFPWMKESRQN+KQK 
Sbjct: 111 PPAPTPAAPPPPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKT 170

Query: 176 SCATAGESCE-DKSPPGPAS-KRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNL 233
           S +++GESC  DKSPPG AS KR RTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNL
Sbjct: 171 SSSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNL 230

Query: 234 TERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLA 293
           TERQIKIWFQNRRMKYKKDQK KG+L S   QSP RSP   GA G++     L  V  + 
Sbjct: 231 TERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSL--VNSVP 288

Query: 294 YDAPSPPAFAKSQPNMYGL--AAYTAPLSSCL---PQQKRYAA--------PEFEPHPMA 340
           Y+  SPP F+K     YGL  A+Y A L SC    P QKRY A        P+++PH   
Sbjct: 289 YEPQSPPPFSKPPQGTYGLPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPHAHG 348

Query: 341 SNG-GGFASANLQGSPVYVGGNFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNH 399
             G G + + ++QGSPV+VGG++VE M+ +   +F L HL H +S ++DY  A  +   H
Sbjct: 349 LQGNGSYGTPHIQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLGSGH 408

Query: 400 HH--GPCDPHPTYTDLSAHHSSQGRLPEAPKLTHL 432
           HH  GP +PHPTYTDL+ HH SQGR+ EAPKLTHL
Sbjct: 409 HHGPGPGEPHPTYTDLTGHHPSQGRIQEAPKLTHL 443


>gi|13562112 homeobox A3 isoform a [Homo sapiens]
          Length = 443

 Score =  401 bits (1030), Expect = e-112
 Identities = 231/455 (50%), Positives = 283/455 (62%), Gaps = 51/455 (11%)

Query: 17  MQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLDTDYPGSACSIQSSAPL 76
           MQKA YY++  ++GGY Y +  + + Y+   QPYP  AA  + D +Y   ACS+QS  P 
Sbjct: 1   MQKATYYDSSAIYGGYPY-QAANGFAYNANQQPYPASAALGA-DGEYHRPACSLQS--PS 56

Query: 77  RAPAH-KGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQ-------------QPPQPPPP 122
            A  H K  EL+ +C+R  +         SQPP L                 QPPQP P 
Sbjct: 57  SAGGHPKAHELSEACLRTLSAPP------SQPPSLGEPPLHPPPPQAAPPAPQPPQPAPQ 110

Query: 123 PPTLPPSSPTNPGGGVPAKKPKGGP---NASSS----SATISKQIFPWMKESRQNSKQKN 175
           PP   P++P  P    P +     P   NA+ S    S T++KQIFPWMKESRQN+KQK 
Sbjct: 111 PPAPTPAAPPPPSSASPPQNASNNPTPANAAKSPLLNSPTVAKQIFPWMKESRQNTKQKT 170

Query: 176 SCATAGESCE-DKSPPGPAS-KRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNL 233
           S +++GESC  DKSPPG AS KR RTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNL
Sbjct: 171 SSSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNL 230

Query: 234 TERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLA 293
           TERQIKIWFQNRRMKYKKDQK KG+L S   QSP RSP   GA G++     L  V  + 
Sbjct: 231 TERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLNSMHSL--VNSVP 288

Query: 294 YDAPSPPAFAKSQPNMYGL--AAYTAPLSSCL---PQQKRYAA--------PEFEPHPMA 340
           Y+  SPP F+K     YGL  A+Y A L SC    P QKRY A        P+++PH   
Sbjct: 289 YEPQSPPPFSKPPQGTYGLPPASYPASLPSCAPPPPPQKRYTAAGAGAGGTPDYDPHAHG 348

Query: 341 SNG-GGFASANLQGSPVYVGGNFVESMAPASGPVFNLGHLSHPSSASVDYSCAAQIPGNH 399
             G G + + ++QGSPV+VGG++VE M+ +   +F L HL H +S ++DY  A  +   H
Sbjct: 349 LQGNGSYGTPHIQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAMDYGGAGPLGSGH 408

Query: 400 HH--GPCDPHPTYTDLSAHHSSQGRLPEAPKLTHL 432
           HH  GP +PHPTYTDL+ HH SQGR+ EAPKLTHL
Sbjct: 409 HHGPGPGEPHPTYTDLTGHHPSQGRIQEAPKLTHL 443


>gi|84570137 homeobox B3 [Homo sapiens]
          Length = 431

 Score =  394 bits (1011), Expect = e-109
 Identities = 230/454 (50%), Positives = 278/454 (61%), Gaps = 61/454 (13%)

Query: 17  MQKAAYYENPG--LFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLDTDYPGSACSIQSSA 74
           MQKA YY+N    LFGGY     ++ +G+  P  P PP  AA+ L+ DY  SACS+QS  
Sbjct: 1   MQKATYYDNAAAALFGGYSSYPGSNGFGFDVP--PQPPFQAATHLEGDYQRSACSLQSLG 58

Query: 75  PLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPPPPP--PTLPPSSPT 132
              AP  K  ELNGSCMRPG            P  L++   PP  PPP   PT   S+ +
Sbjct: 59  NA-APHAKSKELNGSCMRPGLA----------PEPLSA---PPGSPPPSAAPTSATSNSS 104

Query: 133 NPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATAGESCE------- 185
           N GG   +  PK GP  +S   T++KQIFPWMKESRQ SK KN+     E C        
Sbjct: 105 NGGGPSKSGPPKCGPGTNS---TLTKQIFPWMKESRQTSKLKNNSPGTAEGCGGGGGGGG 161

Query: 186 -----------------DKSPPGPA-SKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEM 227
                            DKSPPG A SKR RTAYTSAQLVELEKEFHFNRYLCRPRRVEM
Sbjct: 162 GGGSGGSGGGGGGGGGGDKSPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEM 221

Query: 228 ANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSP--PLGGAAGHVAYSGQ 285
           ANLLNL+ERQIKIWFQNRRMKYKKDQKAKG+  S    SP  SP  P+   AG +     
Sbjct: 222 ANLLNLSERQIKIWFQNRRMKYKKDQKAKGLASSSGGPSPAGSPPQPMQSTAGFMNALHS 281

Query: 286 LPPVPGLAYDAPSPPAFAKSQPNMYGLAA-YTAPLSSCLPQQK--RYAAPEFEPHPMASN 342
           + P    +Y++PSPPAF K+  N Y L + Y  PL  C   QK     APE+EPH + +N
Sbjct: 282 MTP----SYESPSPPAFGKAHQNAYALPSNYQPPLKGCGAPQKYPPTPAPEYEPHVLQAN 337

Query: 343 GGGFASANLQGSPVYV-GGNFVESMAPASGP-VFNLGHLSHPSSASVDYSCAAQIPGNHH 400
           GG + +  +QGSPVYV GG + + + P +GP ++ L HLSH  S ++DY+ A  +  + H
Sbjct: 338 GGAYGTPTMQGSPVYVGGGGYADPLPPPAGPSLYGLNHLSHHPSGNLDYNGAPPMAPSQH 397

Query: 401 HGPCDPHPTYTDLSAHHS--SQGRLPEAPKLTHL 432
           HGPC+PHPTYTDLS+HH+   QGR+ EAPKLTHL
Sbjct: 398 HGPCEPHPTYTDLSSHHAPPPQGRIQEAPKLTHL 431


>gi|24497515 homeobox A3 isoform b [Homo sapiens]
          Length = 285

 Score =  315 bits (806), Expect = 7e-86
 Identities = 170/287 (59%), Positives = 201/287 (70%), Gaps = 20/287 (6%)

Query: 164 MKESRQNSKQKNSCATAGESCE-DKSPPGPAS-KRVRTAYTSAQLVELEKEFHFNRYLCR 221
           MKESRQN+KQK S +++GESC  DKSPPG AS KR RTAYTSAQLVELEKEFHFNRYLCR
Sbjct: 1   MKESRQNTKQKTSSSSSGESCAGDKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCR 60

Query: 222 PRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVA 281
           PRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK KG+L S   QSP RSP   GA G++ 
Sbjct: 61  PRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKGKGMLTSSGGQSPSRSPVPPGAGGYLN 120

Query: 282 YSGQLPPVPGLAYDAPSPPAFAKSQPNMYGL--AAYTAPLSSCL---PQQKRYAA----- 331
               L  V  + Y+  SPP F+K     YGL  A+Y A L SC    P QKRY A     
Sbjct: 121 SMHSL--VNSVPYEPQSPPPFSKPPQGTYGLPPASYPASLPSCAPPPPPQKRYTAAGAGA 178

Query: 332 ---PEFEPHPMASNG-GGFASANLQGSPVYVGGNFVESMAPASGPVFNLGHLSHPSSASV 387
              P+++PH     G G + + ++QGSPV+VGG++VE M+ +   +F L HL H +S ++
Sbjct: 179 GGTPDYDPHAHGLQGNGSYGTPHIQGSPVFVGGSYVEPMSNSGPALFGLTHLPHAASGAM 238

Query: 388 DYSCAAQIPGNHHH--GPCDPHPTYTDLSAHHSSQGRLPEAPKLTHL 432
           DY  A  +   HHH  GP +PHPTYTDL+ HH SQGR+ EAPKLTHL
Sbjct: 239 DYGGAGPLGSGHHHGPGPGEPHPTYTDLTGHHPSQGRIQEAPKLTHL 285


>gi|10140847 homeobox A2 [Homo sapiens]
          Length = 376

 Score =  130 bits (327), Expect = 2e-30
 Identities = 69/157 (43%), Positives = 90/157 (57%), Gaps = 19/157 (12%)

Query: 119 PPPPPPTLPP----SSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQK 174
           PPP   T+P     S P +  GG P   P G   +   +  +    +PWMKE +   K  
Sbjct: 49  PPPFEQTIPSLNPGSHPRHGAGGRPKPSPAGSRGSPVPAGALQPPEYPWMKEKKAAKKTA 108

Query: 175 ---------------NSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYL 219
                           +C +  ES E     G  S+R+RTAYT+ QL+ELEKEFHFN+YL
Sbjct: 109 LLPAAAAAATAAATGPACLSHKESLEIADGSGGGSRRLRTAYTNTQLLELEKEFHFNKYL 168

Query: 220 CRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAK 256
           CRPRRVE+A LL+LTERQ+K+WFQNRRMK+K+  + K
Sbjct: 169 CRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCK 205


>gi|4504465 homeobox B2 [Homo sapiens]
          Length = 356

 Score =  126 bits (317), Expect = 3e-29
 Identities = 85/235 (36%), Positives = 115/235 (48%), Gaps = 48/235 (20%)

Query: 112 SEQQPPQPPPPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNS 171
           +E  P  PPPPPP LP + P      +  KK    P+ S++S + +    P         
Sbjct: 72  AEDGPALPPPPPPPLPAAPPAPEFPWMKEKKSAKKPSQSATSPSPAASAVP--------- 122

Query: 172 KQKNSCATAGESCEDKSPP---GPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMA 228
                 +  G   +    P   G  ++R+RTAYT+ QL+ELEKEFHFN+YLCRPRRVE+A
Sbjct: 123 -----ASGVGSPADGLGLPEAGGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIA 177

Query: 229 NLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPP 288
            LL+LTERQ+K+WFQNRRMK+K+             Q+  R PP G            P 
Sbjct: 178 ALLDLTERQVKVWFQNRRMKHKR-------------QTQHREPPDGE-----------PA 213

Query: 289 VPGLAYDAPSP---PAFAKSQPNMYGLAAYTAPLSSCLPQQKRYAAPEFEPHPMA 340
            PG   D   P   PA +   P+    A+  A  + C P +    A   +P P+A
Sbjct: 214 CPGALEDICDPAEEPAASPGGPS----ASRAAWEACCHPPEVVPGALSADPRPLA 264


>gi|23397672 homeobox D4 [Homo sapiens]
          Length = 255

 Score =  125 bits (314), Expect = 7e-29
 Identities = 100/272 (36%), Positives = 118/272 (43%), Gaps = 61/272 (22%)

Query: 28  LFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLD---TDYPGSACSIQSSAPLRAPAHKGA 84
           L GGY   +  D YG       + PP      D     + GS     S+ P R       
Sbjct: 24  LQGGYLGEQGADYYGGGAQGADFQPPGLYPRPDFGEQPFGGSGPGPGSALPAR------- 76

Query: 85  ELNGSCMRPGTGNSQGGGGGSQP-PGLNSEQQPPQPPPPPPTLP------PSSPTNPGGG 137
                    G G   GG GG    PG   E  P  P PPP  LP       S P  P  G
Sbjct: 77  ---------GHGQEPGGPGGHYAAPG---EPCPAPPAPPPAPLPGARAYSQSDPKQPPSG 124

Query: 138 VPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATAGESCEDKSPPGPASKRV 197
              K+P                ++PWMK+   NS   N   T GE            KR 
Sbjct: 125 TALKQPA--------------VVYPWMKKVHVNSVNPNY--TGGEP-----------KRS 157

Query: 198 RTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKG 257
           RTAYT  Q++ELEKEFHFNRYL R RR+E+A+ L L+ERQIKIWFQNRRMK+KKD K   
Sbjct: 158 RTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPN 217

Query: 258 ILHSPASQSPERSPPLGGAAGHVAYSGQLPPV 289
                +S S   S      +  VA S  L P+
Sbjct: 218 TKGRSSSSSSSSS-----CSSSVAPSQHLQPM 244


>gi|13273315 homeobox B4 [Homo sapiens]
          Length = 251

 Score =  121 bits (303), Expect = 1e-27
 Identities = 77/189 (40%), Positives = 92/189 (48%), Gaps = 42/189 (22%)

Query: 108 PGLNSEQQPPQPPPPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSS-------------- 153
           PG      PP PPPPPP L P +P  P  G    +P     A SSS              
Sbjct: 71  PGPPPPPPPPPPPPPPPGLSPRAPAPPPAGALLPEPGQRCEAVSSSPPPPPCAQNPLHPS 130

Query: 154 ----ATISKQIFPWMKESRQNSKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVEL 209
               A     ++PWM++   ++   N               G   KR RTAYT  Q++EL
Sbjct: 131 PSHSACKEPVVYPWMRKVHVSTVNPNYA-------------GGEPKRSRTAYTRQQVLEL 177

Query: 210 EKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPER 269
           EKEFH+NRYL R RRVE+A+ L L+ERQIKIWFQNRRMK+KKD K            P  
Sbjct: 178 EKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRMKWKKDHKL-----------PNT 226

Query: 270 SPPLGGAAG 278
               GGAAG
Sbjct: 227 KIRSGGAAG 235


>gi|148613882 homeobox A4 [Homo sapiens]
          Length = 320

 Score =  114 bits (285), Expect = 2e-25
 Identities = 95/282 (33%), Positives = 118/282 (41%), Gaps = 41/282 (14%)

Query: 31  GYGYSKTTDTYGYSTPHQPYPPPAAA----SSLDTDYP----GSACSIQSSAPLRAPAHK 82
           G G   T   Y   T  +P  P AA      + DT YP    G A   +   P + PA  
Sbjct: 64  GGGREPTASYYAPRTAREPAYPAAALYPAHGAADTAYPYGYRGGASPGRPPQPEQPPAQA 123

Query: 83  GAELNG----SCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPPPPPPTLPPSSPTNPGGGV 138
               +G      ++P             PP L     PP  P      P +     GG  
Sbjct: 124 KGPAHGLHASHVLQP-----------QLPPPLQPRAVPPAAPRRCEAAPATPGVPAGGSA 172

Query: 139 PAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATAGESCEDKSPPGPASKRVR 198
           PA        +          ++PWMK+                S  + S  G   KR R
Sbjct: 173 PACPLLLADKSPLGLKGKEPVVYPWMKKIHV-------------SAVNPSYNGGEPKRSR 219

Query: 199 TAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGI 258
           TAYT  Q++ELEKEFHFNRYL R RR+E+A+ L L+ERQ+KIWFQNRRMK+KKD K    
Sbjct: 220 TAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKLPNT 279

Query: 259 -LHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYDAPSP 299
            + S  S S    PP  G A     S  L P P  +   P P
Sbjct: 280 KMRSSNSASASAGPP--GKA--QTQSPHLHPHPHPSTSTPVP 317



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 5/69 (7%)

Query: 94  GTGNSQGGGGGSQPPGLNSEQQPPQPPPPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSS 153
           G+G + GG GG   PG    QQPP PP     L      + GGG         P  +   
Sbjct: 28  GSGGADGGPGGG--PGY---QQPPAPPTQHLPLQQPQLPHAGGGREPTASYYAPRTAREP 82

Query: 154 ATISKQIFP 162
           A  +  ++P
Sbjct: 83  AYPAAALYP 91


>gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]
          Length = 283

 Score =  112 bits (280), Expect = 7e-25
 Identities = 93/258 (36%), Positives = 122/258 (47%), Gaps = 64/258 (24%)

Query: 105 SQPPGLNSEQQPPQPPP--------------PPPTLP---PSSPTNPGGG-----VPAK- 141
           S P  L   +QPP PPP              PP   P   P    +P        +PA+ 
Sbjct: 31  SPPACLYMGRQPPPPPPHPFPGALGALEQGSPPDISPYEVPPLADDPAVAHLHHHLPAQL 90

Query: 142 ---KPKGGPNASSSSATISKQI------FPWMKESRQNSKQKNSCATAGESCEDKSPPGP 192
               P  GP    +   + ++       FPWMK ++ ++  K   A    + E +     
Sbjct: 91  ALPHPPAGPFPEGAEPGVLEEPNRVQLPFPWMKSTKAHA-WKGQWAGGAYAAEPEE---- 145

Query: 193 ASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKD 252
            +KR RTAYT AQL+ELEKEF FN+Y+ RPRRVE+A +LNLTER IKIWFQNRRMK+KK+
Sbjct: 146 -NKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQNRRMKWKKE 204

Query: 253 QKAK---------GILHSPASQSPERS----------PPLGG----AAGHVAYSGQLPPV 289
           +  K         G +  P       S          PP GG    AA   A  G+LP  
Sbjct: 205 EDKKRGGGTAVGGGGVAEPEQDCAVTSGEELLALPPPPPPGGAVPPAAPVAAREGRLP-- 262

Query: 290 PGLAYDAPSPPAFAKSQP 307
           PGL+  +P P + A  +P
Sbjct: 263 PGLS-ASPQPSSVAPRRP 279


>gi|24497517 homeobox A5 [Homo sapiens]
          Length = 270

 Score =  112 bits (280), Expect = 7e-25
 Identities = 81/240 (33%), Positives = 104/240 (43%), Gaps = 38/240 (15%)

Query: 31  GYGYS--------KTTDTYGYSTPHQPYPPPAAASSLDTDYPGSACSIQSSAPLRAPAHK 82
           GYGY+          +  +G     + Y   A+A+  +  Y   A S  S  P   P   
Sbjct: 46  GYGYNGMDLSVGRSGSGHFGSGERARSYAASASAAPAEPRYSQPATSTHSPQPDPLPCSA 105

Query: 83  GAELNGSCMRPGTGNSQGGGGGSQPPG----LNSEQQPPQPPPPPPTLPPSSPTNPGGGV 138
            A   GS    G  NS     G+        ++S +            P SS        
Sbjct: 106 VAPSPGSDSHHGGKNSLSNSSGASADAGSTHISSREGVGTASGAEEDAPASSEQASAQSE 165

Query: 139 PAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATAGESCEDKSPPGPASKRVR 198
           P+  P   P           QI+PWM++   +                    GP  KR R
Sbjct: 166 PSPAPPAQP-----------QIYPWMRKLHISHDNIG---------------GPEGKRAR 199

Query: 199 TAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGI 258
           TAYT  Q +ELEKEFHFNRYL R RR+E+A+ L L+ERQIKIWFQNRRMK+KKD K K +
Sbjct: 200 TAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSM 259


>gi|24497538 homeobox C4 [Homo sapiens]
          Length = 264

 Score =  112 bits (280), Expect = 7e-25
 Identities = 88/247 (35%), Positives = 112/247 (45%), Gaps = 56/247 (22%)

Query: 34  YSKTTDTYGYSTPHQP-YPPPAAASSLDTDYPGSACSIQSSAPLRAPAHKGAELNGSCMR 92
           Y +T ++ G+   HQ  YPPP    S    YP    S  S                    
Sbjct: 37  YGRTRES-GFQHHHQELYPPPPPRPS----YPERQYSCTSLQ------------------ 73

Query: 93  PGTGNSQGGG---GGSQPPGLNSEQQPPQPPPPPPTLPPSSPTNPGGGVPAKKPKGGPNA 149
            G GNS+G G    G   P     Q   +P P        SP  P    PA      P+ 
Sbjct: 74  -GPGNSRGHGPAQAGHHHP--EKSQSLCEPAPLSGASASPSPAPPACSQPA------PDH 124

Query: 150 SSSSATISKQIFPWMKESRQNSKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVEL 209
            SS+A+    ++PWMK+   ++   N               G   KR RTAYT  Q++EL
Sbjct: 125 PSSAASKQPIVYPWMKKIHVSTVNPNY-------------NGGEPKRSRTAYTRQQVLEL 171

Query: 210 EKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPER 269
           EKEFH+NRYL R RR+E+A+ L L+ERQIKIWFQNRRMK+KKD       H   +     
Sbjct: 172 EKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKD-------HRLPNTKVRS 224

Query: 270 SPPLGGA 276
           +PP G A
Sbjct: 225 APPAGAA 231


>gi|24497540 homeobox C4 [Homo sapiens]
          Length = 264

 Score =  112 bits (280), Expect = 7e-25
 Identities = 88/247 (35%), Positives = 112/247 (45%), Gaps = 56/247 (22%)

Query: 34  YSKTTDTYGYSTPHQP-YPPPAAASSLDTDYPGSACSIQSSAPLRAPAHKGAELNGSCMR 92
           Y +T ++ G+   HQ  YPPP    S    YP    S  S                    
Sbjct: 37  YGRTRES-GFQHHHQELYPPPPPRPS----YPERQYSCTSLQ------------------ 73

Query: 93  PGTGNSQGGG---GGSQPPGLNSEQQPPQPPPPPPTLPPSSPTNPGGGVPAKKPKGGPNA 149
            G GNS+G G    G   P     Q   +P P        SP  P    PA      P+ 
Sbjct: 74  -GPGNSRGHGPAQAGHHHP--EKSQSLCEPAPLSGASASPSPAPPACSQPA------PDH 124

Query: 150 SSSSATISKQIFPWMKESRQNSKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVEL 209
            SS+A+    ++PWMK+   ++   N               G   KR RTAYT  Q++EL
Sbjct: 125 PSSAASKQPIVYPWMKKIHVSTVNPNY-------------NGGEPKRSRTAYTRQQVLEL 171

Query: 210 EKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPER 269
           EKEFH+NRYL R RR+E+A+ L L+ERQIKIWFQNRRMK+KKD       H   +     
Sbjct: 172 EKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKD-------HRLPNTKVRS 224

Query: 270 SPPLGGA 276
           +PP G A
Sbjct: 225 APPAGAA 231


>gi|13375632 homeobox D1 [Homo sapiens]
          Length = 328

 Score =  110 bits (274), Expect = 3e-24
 Identities = 84/228 (36%), Positives = 110/228 (48%), Gaps = 21/228 (9%)

Query: 52  PPAAASSLDTDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLN 111
           P AAA   D  + GS  +      L   A  G    GS +   T     GGG     G  
Sbjct: 97  PAAAAGGADYGFLGSGPAYDFPGVLGRAADDG----GSHVHYATSAVFSGGGSFLLSGQV 152

Query: 112 SEQQPPQPPPPPPTLPPSSPTNPGG-----GVPAKKPKGGPNASSSSATISKQIFPWMKE 166
                 +P P P  L  S+  +PG        P   PK    AS   A  S   F WMK 
Sbjct: 153 DYAAFGEPGPFPACLKASADGHPGAFQTASPAPGTYPKSVSPASGLPAAFST--FEWMKV 210

Query: 167 SRQNSKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVE 226
            R N+ +K   A  G +    SP    S  +RT +++ QL ELEKEFHFN+YL R RR+E
Sbjct: 211 KR-NASKKGKLAEYGAA----SP----SSAIRTNFSTKQLTELEKEFHFNKYLTRARRIE 261

Query: 227 MANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSPPLG 274
           +AN L+L + Q+KIWFQNRRMK KK ++ +G+L +    +P + P  G
Sbjct: 262 IANCLHLNDTQVKIWFQNRRMKQKKRER-EGLLATAIPVAPLQLPLSG 308


>gi|13489077 homeobox A6 [Homo sapiens]
          Length = 233

 Score =  109 bits (272), Expect = 6e-24
 Identities = 79/210 (37%), Positives = 98/210 (46%), Gaps = 33/210 (15%)

Query: 48  QPYPPPAAASSLDTDYPGSACSIQSSAPLRAPAHKGAELNGSCM---RPGTGNSQGGGGG 104
           +P+P    ASSL      S C  Q S  + A      E   SC    +  +G S  G G 
Sbjct: 36  RPFPASYGASSLPDKTYTSPCFYQQSNSVLACNRASYEYGASCFYSDKDLSGASPSGSGK 95

Query: 105 SQPPGLNSEQQPPQPPPPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWM 164
            + PG      P Q            P +  G   A   +G     +S       ++PWM
Sbjct: 96  QRGPGDYLHFSPEQQ---------YKPDSSSGQGKALHDEGADRKYTSP------VYPWM 140

Query: 165 KESRQNSKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRR 224
           +       + NSCA A          G   +R R  YT  Q +ELEKEFHFNRYL R RR
Sbjct: 141 Q-------RMNSCAGAVY--------GSHGRRGRQTYTRYQTLELEKEFHFNRYLTRRRR 185

Query: 225 VEMANLLNLTERQIKIWFQNRRMKYKKDQK 254
           +E+AN L LTERQIKIWFQNRRMK+KK+ K
Sbjct: 186 IEIANALCLTERQIKIWFQNRRMKWKKENK 215


>gi|4504469 homeobox B5 [Homo sapiens]
          Length = 269

 Score =  107 bits (267), Expect = 2e-23
 Identities = 75/208 (36%), Positives = 102/208 (49%), Gaps = 28/208 (13%)

Query: 53  PAAASSLDTDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNS 112
           PA A         S+CS+  S+P   P   G + +G+     + + Q     S       
Sbjct: 77  PAPAQEPRFRQAASSCSL--SSPESLPCTNG-DSHGAKPSASSPSDQATSASSSANFTEI 133

Query: 113 EQQPPQPPPPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISK--QIFPWMKESRQN 170
           ++      P       SSP+         + +  P A+S++A   +  QIFPWM++   +
Sbjct: 134 DEASASSEPEEAASQLSSPS-------LARAQPEPMATSTAAPEGQTPQIFPWMRKLHIS 186

Query: 171 SKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANL 230
                               GP  KR RTAYT  Q +ELEKEFHFNRYL R RR+E+A+ 
Sbjct: 187 HDMT----------------GPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHA 230

Query: 231 LNLTERQIKIWFQNRRMKYKKDQKAKGI 258
           L L+ERQIKIWFQNRRMK+KKD K K +
Sbjct: 231 LCLSERQIKIWFQNRRMKWKKDNKLKSM 258


>gi|24497526 homeobox B1 [Homo sapiens]
          Length = 301

 Score =  104 bits (260), Expect = 1e-22
 Identities = 92/264 (34%), Positives = 115/264 (43%), Gaps = 48/264 (18%)

Query: 13  PECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTP----HQPYPPPAAASSLDTDYPGSAC 68
           P  + Q    Y + G +GG          G S+P    +  YP     S+L   +P SA 
Sbjct: 32  PPSSAQAVDSYASEGRYGG----------GLSSPAFQQNSGYPAQQPPSTLGVPFPSSAP 81

Query: 69  SIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGG-------GSQPPGLNSEQQP--PQP 119
           S        APA        S   P  G S+G GG       G+Q  GL+         P
Sbjct: 82  SGY------APAACSPSYGPSQYYP-LGQSEGDGGYFHPSSYGAQLGGLSDGYGAGGAGP 134

Query: 120 PPPPPTLPPSSPTNPGGGVPA-----KKPKGGPNASSSSATISKQIFPWMKESRQNSKQK 174
            P PP  PP          PA      + K  P  S  + T + + F WMK  R   K  
Sbjct: 135 GPYPPQHPPYGNEQTASFAPAYADLLSEDKETPCPSEPN-TPTARTFDWMKVKRNPPKTA 193

Query: 175 NSCATAGESCEDKSPPGPASKR-VRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNL 233
                        S PG  S   +RT +T+ QL ELEKEFHFN+YL R RRVE+A  L L
Sbjct: 194 KV-----------SEPGLGSPSGLRTNFTTRQLTELEKEFHFNKYLSRARRVEIAATLEL 242

Query: 234 TERQIKIWFQNRRMKYKKDQKAKG 257
            E Q+KIWFQNRRMK KK ++ +G
Sbjct: 243 NETQVKIWFQNRRMKQKKREREEG 266


>gi|11321638 homeobox C5 [Homo sapiens]
          Length = 222

 Score =  103 bits (257), Expect = 3e-22
 Identities = 77/213 (36%), Positives = 100/213 (46%), Gaps = 44/213 (20%)

Query: 65  GSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPPPPPP 124
           GSA  +Q+S       + G +L+ +   P   NS  G   +  P  + ++        P 
Sbjct: 28  GSASEVQASRY----CYGGLDLSITFPPPAPSNSLHGVDMAANPRAHPDRPACSAAAAPG 83

Query: 125 TLP---PSSPTNPG------------------GGVPAKKPKGGPNASSSSATISKQIFPW 163
             P    ++P NPG                  G +  ++ + G  A  S      QI+PW
Sbjct: 84  HAPGRDEAAPLNPGMYSQKAARPALEERAKSSGEIKEEQAQTGQPAGLSQPPAPPQIYPW 143

Query: 164 MKESRQNSKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPR 223
           M      +K   S  T G             KR RT+YT  Q +ELEKEFHFNRYL R R
Sbjct: 144 M------TKLHMSHETDG-------------KRSRTSYTRYQTLELEKEFHFNRYLTRRR 184

Query: 224 RVEMANLLNLTERQIKIWFQNRRMKYKKDQKAK 256
           R+E+AN L L ERQIKIWFQNRRMK+KKD K K
Sbjct: 185 RIEIANNLCLNERQIKIWFQNRRMKWKKDSKMK 217


>gi|15029506 homeobox D8 [Homo sapiens]
          Length = 290

 Score =  101 bits (252), Expect = 1e-21
 Identities = 79/229 (34%), Positives = 99/229 (43%), Gaps = 44/229 (19%)

Query: 41  YGYSTPHQPYPPPAAASSLDTDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQG 100
           YG S    P+ PP A +                 P  +P   G    G   R G G    
Sbjct: 54  YGNSAAGFPHAPPQAHAH----------------PHPSPPPSGTGCGG---REGRGQEYF 94

Query: 101 GGGGSQPPGLNSEQQPPQPPPPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQ- 159
             GG  P        PP P PPPP  PP     P GG+      G P        + +Q 
Sbjct: 95  HPGGGSPAAAYQAAPPPPPHPPPPPPPP-----PCGGIACH---GEPAKFYGYDNLQRQP 146

Query: 160 IFPWMKESR--QNSKQKNSCATAGESCE----DKSPP----------GPASKRVRTAYTS 203
           IF   +E+   Q    K+S    GE  +      SP            P  +R R  Y+ 
Sbjct: 147 IFTTQQEAELVQYPDCKSSSGNIGEDPDHLNQSSSPSQMFPWMRPQAAPGRRRGRQTYSR 206

Query: 204 AQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKD 252
            Q +ELEKEF FN YL R RR+E+++ L LTERQ+KIWFQNRRMK+KK+
Sbjct: 207 FQTLELEKEFLFNPYLTRKRRIEVSHALALTERQVKIWFQNRRMKWKKE 255


>gi|24497556 homeobox A7 [Homo sapiens]
          Length = 230

 Score =  100 bits (249), Expect = 3e-21
 Identities = 59/133 (44%), Positives = 74/133 (55%), Gaps = 26/133 (19%)

Query: 144 KGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATAGESCEDKSPPGPASKRVRTAYTS 203
           K    A   +A  + +I+PWM+ S                       GP  KR R  YT 
Sbjct: 103 KTDEGALHGAAEANFRIYPWMRSS-----------------------GPDRKRGRQTYTR 139

Query: 204 AQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPA 263
            Q +ELEKEFHFNRYL R RR+E+A+ L LTERQIKIWFQNRRMK+KK+ K +G     A
Sbjct: 140 YQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKDEG---PTA 196

Query: 264 SQSPERSPPLGGA 276
           + +PE + P   A
Sbjct: 197 AAAPEGAVPSAAA 209


>gi|23503237 homeobox B6 [Homo sapiens]
          Length = 224

 Score = 99.4 bits (246), Expect = 6e-21
 Identities = 53/113 (46%), Positives = 69/113 (61%), Gaps = 15/113 (13%)

Query: 157 SKQIFPWMKESRQNSKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFN 216
           S  ++PWM+       + NSC        + S  GP+ +R R  YT  Q +ELEKEFH+N
Sbjct: 124 STPVYPWMQ-------RMNSC--------NSSSFGPSGRRGRQTYTRYQTLELEKEFHYN 168

Query: 217 RYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPER 269
           RYL R RR+E+A+ L LTERQIKIWFQNRRMK+KK+ K        A +  E+
Sbjct: 169 RYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEEEK 221


>gi|33457326 GS homeobox 1 [Homo sapiens]
          Length = 264

 Score = 96.3 bits (238), Expect = 5e-20
 Identities = 63/155 (40%), Positives = 87/155 (56%), Gaps = 24/155 (15%)

Query: 112 SEQQPPQPPPPPPTLPPSSPTNPGGGVPAKKPKG------------GPNASSSSATISKQ 159
           S+   P  PP  P L  S P  P G      P G            GP A++++A + + 
Sbjct: 65  SQLHGPPGPPALPLLKASFP--PFGSQYCHAPLGRQHSAVSPGVAHGPAAAAAAAALYQT 122

Query: 160 IFPWMKESRQNSKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYL 219
            +P + + RQ       C     S +  S   P+SKR+RTA+TS QL+ELE+EF  N YL
Sbjct: 123 SYP-LPDPRQFH-----CI----SVDSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYL 172

Query: 220 CRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 254
            R RR+E+A  LNL+E+Q+KIWFQNRR+K+KK+ K
Sbjct: 173 SRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGK 207


>gi|85068580 homeobox B7 [Homo sapiens]
          Length = 217

 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 74/224 (33%), Positives = 95/224 (42%), Gaps = 52/224 (23%)

Query: 56  ASSLDTDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQG------------GGG 103
           A++L + YP S+    + A    P         +  RPG G   G            GGG
Sbjct: 7   ANTLFSKYPASSSVFATGA---FPEQTSCAFASNPQRPGYGAGSGASFAASMQGLYPGGG 63

Query: 104 GSQPP----------GLNSEQQPPQPPPPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSS 153
           G              GL          P    L    P +      AK+ +    A+ S+
Sbjct: 64  GMAGQSAAGVYAAGYGLEPSSFNMHCAPFEQNLSGVCPGDSAKAAGAKEQRDSDLAAESN 123

Query: 154 ATISKQIFPWMKESRQNSKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEF 213
                +I+PWM+ S                       G   KR R  YT  Q +ELEKEF
Sbjct: 124 F----RIYPWMRSS-----------------------GTDRKRGRQTYTRYQTLELEKEF 156

Query: 214 HFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKG 257
           H+NRYL R RR+E+A+ L LTERQIKIWFQNRRMK+KK+ K  G
Sbjct: 157 HYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRMKWKKENKTAG 200


>gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]
          Length = 411

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 87/287 (30%), Positives = 122/287 (42%), Gaps = 44/287 (15%)

Query: 33  GYSKTTDTYGYSTPHQPYPPPAAASSLDTDYPGSACSIQSSAPLRAPAHKGAELNGSCMR 92
           G ++T DT GYS+    + P A +     + P      +  AP    A +GAE       
Sbjct: 126 GEAETNDTNGYSSGGGGHSPSADSGD---EVPDDEDDDEDEAP-ETEAARGAE------- 174

Query: 93  PGTGNSQGGGGGSQPPGLNSEQQPPQPPPPPPTLPPSSPTNPGGGVP-AKKPKGGPNASS 151
                ++GGGGG    G   +        P  T+  ++   P    P A+ P GG  A  
Sbjct: 175 ----EARGGGGGLGARGSGCQGAAETDASPGATVDEAAAPGPRENSPVAQGPPGGAAAPG 230

Query: 152 SSATISKQIFPWMKESRQNSKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEK 211
            + T  +      K  R+ +         G   +   P     +R RTA+T  QLV LE 
Sbjct: 231 GAGTTPQGTATAAKPKRKRT---------GSDSKSGKP-----RRARTAFTYEQLVALEN 276

Query: 212 EFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSP 271
           +F   RYL    R+ +A  L+LTE Q+KIWFQNRR K+KK            +   + S 
Sbjct: 277 KFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQ-----------NPGADTSA 325

Query: 272 PLGGAAGHVAYSGQLPPVP-GLAYDAPSPPAFAKSQPNMYGLAAYTA 317
           P GG  G    +G    +P GL+  +PSPP  A     M+G A Y A
Sbjct: 326 PTGGGGGPGPGAGPGTGLPGGLSPLSPSPPMGAPL--GMHGPAGYPA 370


>gi|5031761 homeobox A1 isoform a [Homo sapiens]
          Length = 335

 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 86/276 (31%), Positives = 110/276 (39%), Gaps = 29/276 (10%)

Query: 18  QKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLDTDYPGSACSIQSSAPLR 77
           Q A Y  +  L   Y +S    +YG      PY P A     D         +    P  
Sbjct: 76  QPATYQTSGNLGVSYSHSSCGPSYGSQNFSAPYSPYALNQEAD---------VSGGYPQC 126

Query: 78  APAHKGAELNGSCMRPGTGNSQGGGGGSQPPGL--NSEQQPPQPPPPPPTLPPSSPTNPG 135
           APA     L+   ++    +    GG    P    +S  Q  Q           SP +  
Sbjct: 127 APAVYSGNLSSPMVQHHHHHQGYAGGAVGSPQYIHHSYGQEHQSLALATYNNSLSPLHAS 186

Query: 136 GGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATAGESCEDKSPPGPASK 195
                + P       +S  +   Q F WMK  R   K        GE      P      
Sbjct: 187 HQEACRSP-------ASETSSPAQTFDWMKVKRNPPKT----GKVGEYGYLGQP-----N 230

Query: 196 RVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKA 255
            VRT +T+ QL ELEKEFHFN+YL R RRVE+A  L L E Q+KIWFQNRRMK KK +K 
Sbjct: 231 AVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRRMKQKKREKE 290

Query: 256 KGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPG 291
             +  SPA  +P  +      +   + S    P PG
Sbjct: 291 GLLPISPA--TPPGNDEKAEESSEKSSSSPCVPSPG 324


>gi|121114296 caudal type homeobox 1 [Homo sapiens]
          Length = 265

 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 67/202 (33%), Positives = 90/202 (44%), Gaps = 41/202 (20%)

Query: 121 PPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATA 180
           PPP   P  +P  PG G+ A+ P GGP   SS        + WM+ S          A  
Sbjct: 94  PPPDFSPVPAPPGPGPGLLAQ-PLGGPGTPSSPGAQRPTPYEWMRRS---------VAAG 143

Query: 181 GESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKI 240
           G     K+       + R  YT  Q +ELEKEFH++RY+   R+ E+A  L LTERQ+KI
Sbjct: 144 GGGGSGKTR---TKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKI 200

Query: 241 WFQNRRMKYKKDQKAKGILHSPASQSPERSPPLGGAAGHVAYSGQLPPVPGLAYD---AP 297
           WFQNRR K +K  K K                            Q PP P +A+D    P
Sbjct: 201 WFQNRRAKERKVNKKK-------------------------QQQQQPPQPPMAHDITATP 235

Query: 298 SPPAFAKSQPNMYGLAAYTAPL 319
           + P+     P+   L A ++P+
Sbjct: 236 AGPSLGGLCPSNTSLLATSSPM 257


>gi|182765442 homeobox A10 isoform a [Homo sapiens]
          Length = 410

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 67/213 (31%), Positives = 98/213 (46%), Gaps = 40/213 (18%)

Query: 64  PGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGG-----------SQPPGLNS 112
           P   C++ +S+ +  P +            GT    G GGG           +QPPG   
Sbjct: 196 PPDGCALGTSSGVPVPGYFRLS-----QAYGTAKGYGSGGGGAQQLGAGPFPAQPPGRGF 250

Query: 113 EQQPPQPP--------------PPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISK 158
           +  P                  PPPPTL   S    GGG        G   + +S++ ++
Sbjct: 251 DLPPALASGSADAARKERALDSPPPPTLACGS----GGG------SQGDEEAHASSSAAE 300

Query: 159 QIFPWMKESRQNSKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRY 218
           ++ P   ES + S +K+S   +            + ++ R  YT  Q +ELEKEF FN Y
Sbjct: 301 ELSPAPSESSKASPEKDSLGNSKGENAANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMY 360

Query: 219 LCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK 251
           L R RR+E++  ++LT+RQ+KIWFQNRRMK KK
Sbjct: 361 LTRERRLEISRSVHLTDRQVKIWFQNRRMKLKK 393



 Score = 37.7 bits (86), Expect = 0.020
 Identities = 39/136 (28%), Positives = 50/136 (36%), Gaps = 33/136 (24%)

Query: 30  GGYGYSKTTDTYGYSTPHQPYPPPAAASSLDTDYPGSACSIQSSAPLRAPAHKGAELNGS 89
           GG G +      GY      Y PPAA    D  Y   +C +  +         G + N +
Sbjct: 44  GGGGGAGGGGGGGYYAHGGVYLPPAA----DLPYGLQSCGLFPTL--------GGKRNEA 91

Query: 90  CMRPGTGNSQGG------GGGSQPPGL------NSEQQPPQPPPPPPTLPPSSPTNPGGG 137
              PG+G   GG      G G  P  L      +   +PP  PPPPP   P  P  P   
Sbjct: 92  AS-PGSGGGGGGLGPGAHGYGPSPIDLWLDAPRSCRMEPPDGPPPPPQQQPPPPPQP--- 147

Query: 138 VPAKKPKGGPNASSSS 153
                P+  P A+S S
Sbjct: 148 -----PQPAPQATSCS 158


>gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]
          Length = 814

 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 87/287 (30%), Positives = 121/287 (42%), Gaps = 44/287 (15%)

Query: 33  GYSKTTDTYGYSTPHQPYPPPAAASSLDTDYPGSACSIQSSAPLRAPAHKGAELNGSCMR 92
           G ++T DT GYS+    + P A +     + P      +  AP    A +GAE       
Sbjct: 529 GEAETNDTNGYSSGGGGHSPSADSGD---EVPDDEDDDEDEAP-ETEAARGAE------- 577

Query: 93  PGTGNSQGGGGGSQPPGLNSEQQPPQPPPPPPTLPPSSPTNPGGGVP-AKKPKGGPNASS 151
                ++GGGGG    G   +        P  T+  ++   P    P A  P GG  A  
Sbjct: 578 ----EARGGGGGLGARGSGCQGAAETDASPGATVDEAAAPGPRENSPVAPGPPGGAAAPG 633

Query: 152 SSATISKQIFPWMKESRQNSKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEK 211
            + T  +      K  R+ +         G   +   P     +R RTA+T  QLV LE 
Sbjct: 634 GAGTTPQGTATAAKPKRKRT---------GSDSKSGKP-----RRARTAFTYEQLVALEN 679

Query: 212 EFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSP 271
           +F   RYL    R+ +A  L+LTE Q+KIWFQNRR K+KK            +   + S 
Sbjct: 680 KFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQ-----------NPGADTSA 728

Query: 272 PLGGAAGHVAYSGQLPPVP-GLAYDAPSPPAFAKSQPNMYGLAAYTA 317
           P GG  G    +G    +P GL+  +PSPP  A     M+G A Y A
Sbjct: 729 PTGGGGGPGPGAGPGTGLPGGLSPLSPSPPMGAPL--GMHGPAGYPA 773


>gi|169636435 caudal type homeobox 2 [Homo sapiens]
          Length = 313

 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 70/228 (30%), Positives = 107/228 (46%), Gaps = 24/228 (10%)

Query: 54  AAASSLDT-DYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNS 112
           AAA++LD+   PG +      APLR   +  A    +       +   GG  +   G +S
Sbjct: 50  AAAANLDSAQSPGPSWPAAYGAPLREDWNGYAPGGAAAAANAVAHGLNGGSPAAAMGYSS 109

Query: 113 --EQQPPQPPPPPPTLPPSSPTNPGGGVPAKKP-KGGPNASSSSATIS-----KQIFPWM 164
             +  P   P   P  P ++P+   G +    P   GP A++++  +S     + +  WM
Sbjct: 110 PADYHPHHHPHHHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSPGGQRRNLCEWM 169

Query: 165 KESRQNSKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRR 224
           ++  Q S         G   + ++       + R  YT  Q +ELEKEFH++RY+   R+
Sbjct: 170 RKPAQQS--------LGSQVKTRT-----KDKYRVVYTDHQRLELEKEFHYSRYITIRRK 216

Query: 225 VEMANLLNLTERQIKIWFQNRRMKYKKDQKAKGILHSPASQSPERSPP 272
            E+A  L L+ERQ+KIWFQNRR K +K  K K  L     Q P + PP
Sbjct: 217 AELAATLGLSERQVKIWFQNRRAKERKINKKK--LQQQQQQQPPQPPP 262



 Score = 36.6 bits (83), Expect = 0.045
 Identities = 16/27 (59%), Positives = 17/27 (62%), Gaps = 1/27 (3%)

Query: 113 EQQPPQPPPPPPTLPPSSPTNPGGGVP 139
           +QQPPQPPPPPP  PP     P   VP
Sbjct: 254 QQQPPQPPPPPPQ-PPQPQPGPLRSVP 279



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 2/44 (4%)

Query: 113 EQQPPQPPPPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATI 156
           +QQ  QPP PPP  PP  P  P  G     P+     SS  A++
Sbjct: 251 QQQQQQPPQPPP--PPPQPPQPQPGPLRSVPEPLSPVSSLQASV 292


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.130    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,302,110
Number of Sequences: 37866
Number of extensions: 1624952
Number of successful extensions: 31064
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 958
Number of HSP's successfully gapped in prelim test: 1198
Number of HSP's that attempted gapping in prelim test: 12326
Number of HSP's gapped (non-prelim): 11447
length of query: 432
length of database: 18,247,518
effective HSP length: 105
effective length of query: 327
effective length of database: 14,271,588
effective search space: 4666809276
effective search space used: 4666809276
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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