Guide to the Human Genome
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Search of human proteins with 19882217

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19882217 mitochondrial translation optimization 1 homolog
isoform b [Homo sapiens]
         (717 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19882217 mitochondrial translation optimization 1 homolog iso...  1434   0.0  
gi|74024895 mitochondrial translation optimization 1 homolog iso...  1368   0.0  
gi|183227703 mitochondrial translation optimization 1 homolog is...  1349   0.0  
gi|223029405 zinc finger protein 619 isoform 3 [Homo sapiens]          39   0.022
gi|94680985 cyclin J-like [Homo sapiens]                               38   0.029
gi|170932471 hypothetical protein LOC79703 [Homo sapiens]              38   0.029
gi|148277071 thioredoxin reductase 1 isoform 3 [Homo sapiens]          35   0.19 
gi|148277065 thioredoxin reductase 1 isoform 1 [Homo sapiens]          35   0.19 
gi|5454102 transforming, acidic coiled-coil containing protein 3...    35   0.24 
gi|51243063 MAD2L1 binding protein isoform 1 [Homo sapiens]            34   0.54 
gi|33519426 thioredoxin reductase 1 isoform 2 [Homo sapiens]           34   0.54 
gi|33519430 thioredoxin reductase 1 isoform 2 [Homo sapiens]           34   0.54 
gi|33519428 thioredoxin reductase 1 isoform 2 [Homo sapiens]           34   0.54 
gi|219881538 hypothetical protein LOC199870 isoform 2 [Homo sapi...    33   0.70 
gi|219881536 hypothetical protein LOC199870 isoform 1 [Homo sapi...    33   0.70 
gi|229577391 pyridine nucleotide-disulphide oxidoreductase domai...    33   0.92 
gi|6005810 mitogen-activated protein kinase kinase kinase kinase...    33   1.2  
gi|23943928 hypothetical protein LOC140680 [Homo sapiens]              33   1.2  
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]    32   1.6  
gi|60099474 tripartite motif-containing 61 [Homo sapiens]              32   1.6  
gi|203098013 all-trans-13,14-dihydroretinol saturase [Homo sapiens]    32   1.6  
gi|239735607 nucleoredoxin-like 2 isoform 2 [Homo sapiens]             32   2.0  
gi|8923708 FAD-dependent oxidoreductase domain containing 1 [Hom...    32   2.0  
gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1 [...    32   2.7  
gi|119943098 dihydropyrimidine dehydrogenase isoform 1 [Homo sap...    32   2.7  
gi|66348062 fumarylacetoacetate hydrolase domain containing 1 is...    32   2.7  
gi|148839316 NIMA-related kinase 4 [Homo sapiens]                      31   3.5  
gi|133908616 glycerol-3-phosphate dehydrogenase 2, mitochondrial...    31   3.5  
gi|133908614 glycerol-3-phosphate dehydrogenase 2, mitochondrial...    31   3.5  
gi|62543567 nudix (nucleoside diphosphate linked moiety X)-type ...    31   3.5  

>gi|19882217 mitochondrial translation optimization 1 homolog
           isoform b [Homo sapiens]
          Length = 717

 Score = 1434 bits (3713), Expect = 0.0
 Identities = 717/717 (100%), Positives = 717/717 (100%)

Query: 1   MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS 60
           MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS
Sbjct: 1   MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS 60

Query: 61  RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP 120
           RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP
Sbjct: 61  RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP 120

Query: 121 AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD 180
           AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD
Sbjct: 121 AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD 180

Query: 181 GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP 240
           GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP
Sbjct: 181 GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP 240

Query: 241 PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH 300
           PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH
Sbjct: 241 PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH 300

Query: 301 LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK 360
           LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK
Sbjct: 301 LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK 360

Query: 361 MITCIRGLEKAKVIQPDGVLLLLPRMECNGAISAHHNLPLPGYGVQYDYLDPRQITPSLE 420
           MITCIRGLEKAKVIQPDGVLLLLPRMECNGAISAHHNLPLPGYGVQYDYLDPRQITPSLE
Sbjct: 361 MITCIRGLEKAKVIQPDGVLLLLPRMECNGAISAHHNLPLPGYGVQYDYLDPRQITPSLE 420

Query: 421 THLVQRLFFAGQINGTTGYEEAAAQGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLT 480
           THLVQRLFFAGQINGTTGYEEAAAQGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLT
Sbjct: 421 THLVQRLFFAGQINGTTGYEEAAAQGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLT 480

Query: 481 TLGTSEPYRMFTSRVEFRLSLRPDNADSRLTLRGYKDAGCVSQQRYERACWMKSSLEEGI 540
           TLGTSEPYRMFTSRVEFRLSLRPDNADSRLTLRGYKDAGCVSQQRYERACWMKSSLEEGI
Sbjct: 481 TLGTSEPYRMFTSRVEFRLSLRPDNADSRLTLRGYKDAGCVSQQRYERACWMKSSLEEGI 540

Query: 541 SVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEVDMDSLAKAVPEPLKKYTKC 600
           SVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEVDMDSLAKAVPEPLKKYTKC
Sbjct: 541 SVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEVDMDSLAKAVPEPLKKYTKC 600

Query: 601 RELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIRDVSLSHEVREKLHFS 660
           RELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIRDVSLSHEVREKLHFS
Sbjct: 601 RELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIRDVSLSHEVREKLHFS 660

Query: 661 RPQTIGAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQYLCDADRLQEREL 717
           RPQTIGAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQYLCDADRLQEREL
Sbjct: 661 RPQTIGAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQYLCDADRLQEREL 717


>gi|74024895 mitochondrial translation optimization 1 homolog
           isoform a [Homo sapiens]
          Length = 692

 Score = 1368 bits (3542), Expect = 0.0
 Identities = 692/717 (96%), Positives = 692/717 (96%), Gaps = 25/717 (3%)

Query: 1   MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS 60
           MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS
Sbjct: 1   MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS 60

Query: 61  RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP 120
           RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP
Sbjct: 61  RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP 120

Query: 121 AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD 180
           AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD
Sbjct: 121 AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD 180

Query: 181 GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP 240
           GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP
Sbjct: 181 GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP 240

Query: 241 PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH 300
           PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH
Sbjct: 241 PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH 300

Query: 301 LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK 360
           LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK
Sbjct: 301 LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK 360

Query: 361 MITCIRGLEKAKVIQPDGVLLLLPRMECNGAISAHHNLPLPGYGVQYDYLDPRQITPSLE 420
           MITCIRGLEKAKVIQ                         PGYGVQYDYLDPRQITPSLE
Sbjct: 361 MITCIRGLEKAKVIQ-------------------------PGYGVQYDYLDPRQITPSLE 395

Query: 421 THLVQRLFFAGQINGTTGYEEAAAQGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLT 480
           THLVQRLFFAGQINGTTGYEEAAAQGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLT
Sbjct: 396 THLVQRLFFAGQINGTTGYEEAAAQGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLT 455

Query: 481 TLGTSEPYRMFTSRVEFRLSLRPDNADSRLTLRGYKDAGCVSQQRYERACWMKSSLEEGI 540
           TLGTSEPYRMFTSRVEFRLSLRPDNADSRLTLRGYKDAGCVSQQRYERACWMKSSLEEGI
Sbjct: 456 TLGTSEPYRMFTSRVEFRLSLRPDNADSRLTLRGYKDAGCVSQQRYERACWMKSSLEEGI 515

Query: 541 SVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEVDMDSLAKAVPEPLKKYTKC 600
           SVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEVDMDSLAKAVPEPLKKYTKC
Sbjct: 516 SVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEVDMDSLAKAVPEPLKKYTKC 575

Query: 601 RELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIRDVSLSHEVREKLHFS 660
           RELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIRDVSLSHEVREKLHFS
Sbjct: 576 RELAERLKIEATYESVLFHQLQEIKGVQQDEALQLPKDLDYLTIRDVSLSHEVREKLHFS 635

Query: 661 RPQTIGAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQYLCDADRLQEREL 717
           RPQTIGAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQYLCDADRLQEREL
Sbjct: 636 RPQTIGAASRIPGVTPAAIINLLRFVKTTQRRQSAMNESSKTDQYLCDADRLQEREL 692


>gi|183227703 mitochondrial translation optimization 1 homolog
           isoform c [Homo sapiens]
          Length = 732

 Score = 1349 bits (3491), Expect = 0.0
 Identities = 692/757 (91%), Positives = 692/757 (91%), Gaps = 65/757 (8%)

Query: 1   MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS 60
           MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS
Sbjct: 1   MFYFRGCGRWVAVSFTKQQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGS 60

Query: 61  RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP 120
           RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP
Sbjct: 61  RTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGVHYKVLNRRKGP 120

Query: 121 AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD 180
           AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD
Sbjct: 121 AVWGLRAQIDRKLYKQNMQKEILNTPLLTVQEGAVEDLILTEPEPEHTGKCRVSGVVLVD 180

Query: 181 GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP 240
           GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP
Sbjct: 181 GSTVYAESVILTTGTFLRGMIVIGLETHPAGRLGDQPSIGLAQTLEKLGFVVGRLKTGTP 240

Query: 241 PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH 300
           PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH
Sbjct: 241 PRIAKESINFSILNKHIPDNPSIPFSFTNETVWIKPEDQLPCYLTHTNPRVDEIVLKNLH 300

Query: 301 LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK 360
           LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK
Sbjct: 301 LNSHVKETTRGPRYCPSIESKVLRFPNRLHQVWLEPEGMDSDLIYPQGLSMTLPAELQEK 360

Query: 361 MITCIRGLEKAKVIQPDGVLLLLPRMECNGAISAHHNLPLPGYGVQYDYLDPRQITPSLE 420
           MITCIRGLEKAKVIQ                         PGYGVQYDYLDPRQITPSLE
Sbjct: 361 MITCIRGLEKAKVIQ-------------------------PGYGVQYDYLDPRQITPSLE 395

Query: 421 THLVQRLFFAGQINGTTGYEEAAA------------------------------------ 444
           THLVQRLFFAGQINGTTGYEEAAA                                    
Sbjct: 396 THLVQRLFFAGQINGTTGYEEAAAQTECCSVARLECSDMISQLQAILLPQPSLVAGTAGM 455

Query: 445 ----QGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLS 500
               QGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLS
Sbjct: 456 HHNTQGVIAGINASLRVSRKPPFVVSRTEGYIGVLIDDLTTLGTSEPYRMFTSRVEFRLS 515

Query: 501 LRPDNADSRLTLRGYKDAGCVSQQRYERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEA 560
           LRPDNADSRLTLRGYKDAGCVSQQRYERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEA
Sbjct: 516 LRPDNADSRLTLRGYKDAGCVSQQRYERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEA 575

Query: 561 SISTSRSLPVRALDVLKYEEVDMDSLAKAVPEPLKKYTKCRELAERLKIEATYESVLFHQ 620
           SISTSRSLPVRALDVLKYEEVDMDSLAKAVPEPLKKYTKCRELAERLKIEATYESVLFHQ
Sbjct: 576 SISTSRSLPVRALDVLKYEEVDMDSLAKAVPEPLKKYTKCRELAERLKIEATYESVLFHQ 635

Query: 621 LQEIKGVQQDEALQLPKDLDYLTIRDVSLSHEVREKLHFSRPQTIGAASRIPGVTPAAII 680
           LQEIKGVQQDEALQLPKDLDYLTIRDVSLSHEVREKLHFSRPQTIGAASRIPGVTPAAII
Sbjct: 636 LQEIKGVQQDEALQLPKDLDYLTIRDVSLSHEVREKLHFSRPQTIGAASRIPGVTPAAII 695

Query: 681 NLLRFVKTTQRRQSAMNESSKTDQYLCDADRLQEREL 717
           NLLRFVKTTQRRQSAMNESSKTDQYLCDADRLQEREL
Sbjct: 696 NLLRFVKTTQRRQSAMNESSKTDQYLCDADRLQEREL 732


>gi|223029405 zinc finger protein 619 isoform 3 [Homo sapiens]
          Length = 567

 Score = 38.5 bits (88), Expect = 0.022
 Identities = 17/24 (70%), Positives = 18/24 (75%)

Query: 379 VLLLLPRMECNGAISAHHNLPLPG 402
           V LLLPR+ECNG I  H NL LPG
Sbjct: 67  VSLLLPRLECNGVIFTHRNLCLPG 90


>gi|94680985 cyclin J-like [Homo sapiens]
          Length = 435

 Score = 38.1 bits (87), Expect = 0.029
 Identities = 17/26 (65%), Positives = 21/26 (80%)

Query: 377 DGVLLLLPRMECNGAISAHHNLPLPG 402
           +GV LL PR++C+G ISAH NL LPG
Sbjct: 94  NGVSLLSPRLKCSGMISAHCNLHLPG 119


>gi|170932471 hypothetical protein LOC79703 [Homo sapiens]
          Length = 677

 Score = 38.1 bits (87), Expect = 0.029
 Identities = 17/23 (73%), Positives = 19/23 (82%)

Query: 380 LLLLPRMECNGAISAHHNLPLPG 402
           L LLPR EC+GA+SAH NL LPG
Sbjct: 109 LTLLPRPECSGAVSAHCNLHLPG 131


>gi|148277071 thioredoxin reductase 1 isoform 3 [Homo sapiens]
          Length = 649

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 15/44 (34%), Positives = 27/44 (61%)

Query: 22  LARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLL 65
           L +++     P++  +D+I+IGGG  G  AA  AA+ G + ++L
Sbjct: 148 LLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVL 191


>gi|148277065 thioredoxin reductase 1 isoform 1 [Homo sapiens]
          Length = 551

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 15/44 (34%), Positives = 27/44 (61%)

Query: 22 LARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLL 65
          L +++     P++  +D+I+IGGG  G  AA  AA+ G + ++L
Sbjct: 50 LLKMNGPEDLPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVL 93


>gi|5454102 transforming, acidic coiled-coil containing protein 3
           [Homo sapiens]
          Length = 838

 Score = 35.0 bits (79), Expect = 0.24
 Identities = 23/79 (29%), Positives = 45/79 (56%), Gaps = 8/79 (10%)

Query: 573 LDVLKYEEVDMDSLAKAVPEPLKKY-TKCREL----AERLKIEATYESVLFHQLQEI--- 624
           +D+L+Y + D+D++ KA  E  ++  ++C EL     E  KI   +E V++  ++E+   
Sbjct: 634 VDLLQYSQKDLDAVVKATQEENRELRSRCEELHGKNLELGKIMDRFEEVVYQAMEEVQKQ 693

Query: 625 KGVQQDEALQLPKDLDYLT 643
           K + + E  ++ K+ D LT
Sbjct: 694 KELSKAEIQKVLKEKDQLT 712


>gi|51243063 MAD2L1 binding protein isoform 1 [Homo sapiens]
          Length = 306

 Score = 33.9 bits (76), Expect = 0.54
 Identities = 15/23 (65%), Positives = 16/23 (69%)

Query: 380 LLLLPRMECNGAISAHHNLPLPG 402
           L L PR+E NG  SAHHN  LPG
Sbjct: 10  LTLSPRLEHNGMTSAHHNFRLPG 32


>gi|33519426 thioredoxin reductase 1 isoform 2 [Homo sapiens]
          Length = 499

 Score = 33.9 bits (76), Expect = 0.54
 Identities = 14/34 (41%), Positives = 23/34 (67%)

Query: 32 PRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLL 65
          P++  +D+I+IGGG  G  AA  AA+ G + ++L
Sbjct: 8  PKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVL 41


>gi|33519430 thioredoxin reductase 1 isoform 2 [Homo sapiens]
          Length = 499

 Score = 33.9 bits (76), Expect = 0.54
 Identities = 14/34 (41%), Positives = 23/34 (67%)

Query: 32 PRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLL 65
          P++  +D+I+IGGG  G  AA  AA+ G + ++L
Sbjct: 8  PKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVL 41


>gi|33519428 thioredoxin reductase 1 isoform 2 [Homo sapiens]
          Length = 499

 Score = 33.9 bits (76), Expect = 0.54
 Identities = 14/34 (41%), Positives = 23/34 (67%)

Query: 32 PRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLL 65
          P++  +D+I+IGGG  G  AA  AA+ G + ++L
Sbjct: 8  PKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVL 41


>gi|219881538 hypothetical protein LOC199870 isoform 2 [Homo
           sapiens]
          Length = 312

 Score = 33.5 bits (75), Expect = 0.70
 Identities = 14/18 (77%), Positives = 15/18 (83%)

Query: 385 RMECNGAISAHHNLPLPG 402
           R+ECNG ISAH NL LPG
Sbjct: 49  RLECNGTISAHCNLHLPG 66


>gi|219881536 hypothetical protein LOC199870 isoform 1 [Homo
           sapiens]
          Length = 341

 Score = 33.5 bits (75), Expect = 0.70
 Identities = 14/18 (77%), Positives = 15/18 (83%)

Query: 385 RMECNGAISAHHNLPLPG 402
           R+ECNG ISAH NL LPG
Sbjct: 49  RLECNGTISAHCNLHLPG 66


>gi|229577391 pyridine nucleotide-disulphide oxidoreductase domain
          2 [Homo sapiens]
          Length = 581

 Score = 33.1 bits (74), Expect = 0.92
 Identities = 20/62 (32%), Positives = 26/62 (41%), Gaps = 1/62 (1%)

Query: 8  GRWVAVSFTKQQFPLARLSSDSA-APRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLLT 66
          GR +  +     FP  R  +  A     P +D +VIG GH G  AA    R G  T +  
Sbjct: 5  GRGLCKAVAASPFPAWRRDNTEARGGLKPEYDAVVIGAGHNGLVAAAYLQRLGVNTAVFE 64

Query: 67 HR 68
           R
Sbjct: 65 RR 66


>gi|6005810 mitogen-activated protein kinase kinase kinase kinase 1
           isoform 2 [Homo sapiens]
          Length = 833

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 15/23 (65%), Positives = 17/23 (73%)

Query: 380 LLLLPRMECNGAISAHHNLPLPG 402
           LL  PR+EC+G IS H NL LPG
Sbjct: 794 LLGSPRLECSGTISPHCNLLLPG 816


>gi|23943928 hypothetical protein LOC140680 [Homo sapiens]
          Length = 363

 Score = 32.7 bits (73), Expect = 1.2
 Identities = 41/143 (28%), Positives = 60/143 (41%), Gaps = 43/143 (30%)

Query: 532 MKSSLEEGISVLKSIE----FLSSKWKKLIPEAS-ISTSRSLPVRAL-----------DV 575
           MK+SL  G + L+ +     FLS   ++LI     +  S +L VRAL           D+
Sbjct: 101 MKTSLRSGRAALRELRSRENFLSKLNRELIETIQEMENSTTLHVRALLQQQDTLATIIDI 160

Query: 576 LKYEEVDMDSLAKAVPEPLKKYTKCR-----ELAERL--KIEATYESV------------ 616
           L+Y         K+  +  ++  KC+     + AE+L  KIE T E V            
Sbjct: 161 LEYSNKKRLQQLKSELQEWEEKKKCKMSYLEQQAEQLNAKIEKTQEEVNFLSTYMDHEYS 220

Query: 617 --------LFHQLQEIKGVQQDE 631
                   L  QLQ++K  QQDE
Sbjct: 221 IKSVQISTLMRQLQQVKDSQQDE 243


>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
          Length = 1233

 Score = 32.3 bits (72), Expect = 1.6
 Identities = 37/158 (23%), Positives = 77/158 (48%), Gaps = 20/158 (12%)

Query: 522 SQQRYERACWMKSSLEEGISVLKSIEFLSSKWKKLIPEASISTSRSLPVRALDVLKYEEV 581
           +Q+ Y++    K  ++E    + S+E    ++++ + E S S  R L +    V KY  +
Sbjct: 322 AQKHYKKR---KGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRL 378

Query: 582 DMDSLAKA--VPEPLKKYTKCR-------ELAERLKIEATYESVLFHQLQEIKGVQQDEA 632
             ++  +A  + + L+K+ + +       +L ER K+E   E+ +  +L+EI+  Q+   
Sbjct: 379 KEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVET--EAKIKQKLREIEENQK--- 433

Query: 633 LQLPKDLDYLTIRDVSLSHEVREKLHFSRPQTIGAASR 670
            ++ K  +Y+T    SL  E ++KL     + +  A R
Sbjct: 434 -RIEKLEEYITTSKQSL--EEQKKLEGELTEEVEMAKR 468


>gi|60099474 tripartite motif-containing 61 [Homo sapiens]
          Length = 209

 Score = 32.3 bits (72), Expect = 1.6
 Identities = 22/49 (44%), Positives = 28/49 (57%), Gaps = 6/49 (12%)

Query: 356 ELQEKMITCI--RGLEKAKVIQPDGVLLLLPRMECNGAISAHHNLPLPG 402
           EL EK+IT    + LE  K ++   V     R+EC+  ISAH NL LPG
Sbjct: 156 ELIEKVITMQTRKSLELKKKMESPSVT----RLECSCTISAHFNLRLPG 200


>gi|203098013 all-trans-13,14-dihydroretinol saturase [Homo sapiens]
          Length = 610

 Score = 32.3 bits (72), Expect = 1.6
 Identities = 19/48 (39%), Positives = 23/48 (47%), Gaps = 3/48 (6%)

Query: 38  DVIVIGGGHAGTEAATAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIG 85
           DV+VIG G  G  AA   A+ G R L+L       G   C  +FG  G
Sbjct: 69  DVVVIGSGFGGLAAAAILAKAGKRVLVLEQHTKAGG---CCHTFGKNG 113


>gi|239735607 nucleoredoxin-like 2 isoform 2 [Homo sapiens]
          Length = 135

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 15/23 (65%), Positives = 17/23 (73%)

Query: 380 LLLLPRMECNGAISAHHNLPLPG 402
           L LLPR+EC+G I AH NL L G
Sbjct: 104 LALLPRLECSGVILAHCNLCLLG 126


>gi|8923708 FAD-dependent oxidoreductase domain containing 1 [Homo
           sapiens]
          Length = 486

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 4/64 (6%)

Query: 25  LSSDSAAPRTPHFDVIVIGGGHAGTEAA----TAAARCGSRTLLLTHRVDTIGQMSCNPS 80
           L  D++     H DV+++GGG  G   A       +R G+  +L+  R  T  Q S   S
Sbjct: 52  LLQDTSHLPPEHSDVVIVGGGVLGLSVAYWLKKLESRRGAIRVLVVERDHTYSQASTGLS 111

Query: 81  FGGI 84
            GGI
Sbjct: 112 VGGI 115


>gi|217035093 cyclic nucleotide gated channel alpha 1 isoform 1
           [Homo sapiens]
          Length = 759

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 13/18 (72%), Positives = 16/18 (88%)

Query: 384 PRMECNGAISAHHNLPLP 401
           PR+EC+GAISAH +L LP
Sbjct: 7   PRLECSGAISAHCSLHLP 24


>gi|119943098 dihydropyrimidine dehydrogenase isoform 1 [Homo
           sapiens]
          Length = 1025

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 13/30 (43%), Positives = 19/30 (63%)

Query: 39  VIVIGGGHAGTEAATAAARCGSRTLLLTHR 68
           VIV+G G    + AT+A RCG+R + +  R
Sbjct: 335 VIVLGAGDTAFDCATSALRCGARRVFIVFR 364


>gi|66348062 fumarylacetoacetate hydrolase domain containing 1
           isoform 1 [Homo sapiens]
          Length = 248

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 13/23 (56%), Positives = 18/23 (78%)

Query: 380 LLLLPRMECNGAISAHHNLPLPG 402
           L L P++EC+ AI+AH +L LPG
Sbjct: 216 LTLSPKLECSSAITAHCSLELPG 238


>gi|148839316 NIMA-related kinase 4 [Homo sapiens]
          Length = 841

 Score = 31.2 bits (69), Expect = 3.5
 Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 8/42 (19%)

Query: 369 EKAKVIQP--------DGVLLLLPRMECNGAISAHHNLPLPG 402
           E  K +QP        D  L L P++EC+G I AH NL L G
Sbjct: 439 EPVKPLQPLIKEQKPKDQSLALSPKLECSGTILAHSNLRLLG 480


>gi|133908616 glycerol-3-phosphate dehydrogenase 2, mitochondrial
           [Homo sapiens]
          Length = 727

 Score = 31.2 bits (69), Expect = 3.5
 Identities = 20/64 (31%), Positives = 30/64 (46%)

Query: 34  TPHFDVIVIGGGHAGTEAATAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREV 93
           T  FD++VIGGG  G+  A  A   G +T L+     + G  S +      G  +L + +
Sbjct: 67  TSEFDILVIGGGATGSGCALDAVTRGLKTALVERDDFSSGTSSRSTKLIHGGVRYLQKAI 126

Query: 94  DALD 97
             LD
Sbjct: 127 MKLD 130


>gi|133908614 glycerol-3-phosphate dehydrogenase 2, mitochondrial
           [Homo sapiens]
          Length = 727

 Score = 31.2 bits (69), Expect = 3.5
 Identities = 20/64 (31%), Positives = 30/64 (46%)

Query: 34  TPHFDVIVIGGGHAGTEAATAAARCGSRTLLLTHRVDTIGQMSCNPSFGGIGKGHLMREV 93
           T  FD++VIGGG  G+  A  A   G +T L+     + G  S +      G  +L + +
Sbjct: 67  TSEFDILVIGGGATGSGCALDAVTRGLKTALVERDDFSSGTSSRSTKLIHGGVRYLQKAI 126

Query: 94  DALD 97
             LD
Sbjct: 127 MKLD 130


>gi|62543567 nudix (nucleoside diphosphate linked moiety X)-type
           motif 17 [Homo sapiens]
          Length = 328

 Score = 31.2 bits (69), Expect = 3.5
 Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 6/93 (6%)

Query: 18  QQFPLARLSSDSAAPRTPHFDVIVIGGGHAGTEAATAAARCGSRTLLLTHRVDTIGQMSC 77
           Q+ P    ++    PR P  ++    G   G      ++    +T+LLT R  T+   S 
Sbjct: 64  QRPPFCPFAALEERPRVPGAELPTDRGVDLGVAVILQSS---DKTVLLTRRARTL---SV 117

Query: 78  NPSFGGIGKGHLMREVDALDGLCSRICDQSGVH 110
           +P+      GH+  E + LDG    + ++SG+H
Sbjct: 118 SPNLWVPPGGHVELEEELLDGGLRELWEESGLH 150


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,352,494
Number of Sequences: 37866
Number of extensions: 1228708
Number of successful extensions: 2656
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 2620
Number of HSP's gapped (non-prelim): 49
length of query: 717
length of database: 18,247,518
effective HSP length: 110
effective length of query: 607
effective length of database: 14,082,258
effective search space: 8547930606
effective search space used: 8547930606
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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