Guide to the Human Genome
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Name: DPYD Sequence: fasta or formatted (1025aa) NCBI GI: 119943098
Description:

dihydropyrimidine dehydrogenase isoform 1

Referenced in:

Pyrimidine Biosynthesis and Catabolism

Other entries for this name:
alt prot [173aa] dihydropyrimidine dehydrogenase isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.4         86           2
 C cysteine            3.5         36           1
 D aspartate           4.9         50           2
 E glutamate           5.8         59           2
 F phenylalanine       4.2         43           2
 G glycine             7.7         79           2
 H histidine           1.0         10           1
 I isoleucine          6.8         70           2
 K lysine              6.8         70           2
 L leucine             8.1         83           2
 M methionine          2.4         25           1
 N asparagine          3.9         40           2
 P proline             6.0         62           3
 Q glutamine           3.4         35           2
 R arginine            3.7         38           2
 S serine              7.3         75           2
 T threonine           6.1         63           2
 V valine              6.4         66           2
 W tryptophan          1.1         11           1
 Y tyrosine            2.3         24           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   dihydropyrimidine dehydrogenase isoform 1 
DPYD                  0.154   dihydropyrimidine dehydrogenase isoform 2 
DHODH                 0.016   dihydroorotate dehydrogenase precursor 
DUS1L                 0.005   PP3111 protein 
SMOX                  0.004   spermine oxidase isoform 4 
SMOX                  0.004   spermine oxidase isoform 3 
SMOX                  0.004   spermine oxidase isoform 2 
SMOX                  0.004   spermine oxidase isoform 1 
MYOG                  0.004   myogenin 
FIGLA                 0.004   factor in the germline alpha 
DUS4L                 0.004   dihydrouridine synthase 4-like 
ABCE1                 0.004   ATP-binding cassette, sub-family E, member 1 
ABCE1                 0.004   ATP-binding cassette, sub-family E, member 1 
MTO1                  0.003   mitochondrial translation optimization 1 homolog is...
MTO1                  0.003   mitochondrial translation optimization 1 homolog iso...
MTO1                  0.003   mitochondrial translation optimization 1 homolog iso...
PIK3C2A               0.003   phosphoinositide-3-kinase, class 2 alpha polypeptid...
HOOK2                 0.003   hook homolog 2 isoform 2 
HOOK2                 0.003   hook homolog 2 isoform 1 
PYROXD2               0.002   pyridine nucleotide-disulphide oxidoreductase domai...
SYNE1                 0.002   spectrin repeat containing, nuclear envelope 1 isofo...
SYNE1                 0.002   spectrin repeat containing, nuclear envelope 1 isof...
ZNF100                0.002   zinc finger protein 100 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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