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Search of human proteins with 19743905
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19743905 RAR-related orphan receptor A isoform d [Homo
sapiens]
(468 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19743905 RAR-related orphan receptor A isoform d [Homo sapiens] 957 0.0
gi|4506577 RAR-related orphan receptor A isoform c [Homo sapiens] 941 0.0
gi|19743901 RAR-related orphan receptor A isoform b [Homo sapiens] 940 0.0
gi|19743903 RAR-related orphan receptor A isoform a [Homo sapiens] 937 0.0
gi|19743907 RAR-related orphan receptor B [Homo sapiens] 585 e-167
gi|48255918 RAR-related orphan receptor C isoform b [Homo sapiens] 458 e-129
gi|19743909 RAR-related orphan receptor C isoform a [Homo sapiens] 456 e-128
gi|224177493 nuclear receptor subfamily 1, group D, member 2 iso... 143 4e-34
gi|224177491 nuclear receptor subfamily 1, group D, member 2 iso... 143 4e-34
gi|189491739 nuclear receptor subfamily 2, group C, member 1 iso... 132 5e-31
gi|13430848 nuclear receptor subfamily 1, group D, member 1 [Hom... 128 1e-29
gi|45545405 nuclear receptor subfamily 5, group A, member 2 isof... 124 2e-28
gi|4504343 nuclear receptor subfamily 5, group A, member 2 isofo... 124 2e-28
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens] 122 5e-28
gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens] 122 5e-28
gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens] 122 9e-28
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 120 3e-27
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens] 120 3e-27
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 120 3e-27
gi|4506755 retinoid X receptor, alpha [Homo sapiens] 115 7e-26
gi|189491766 nuclear receptor subfamily 2, group C, member 1 iso... 114 1e-25
gi|73808084 nuclear receptor subfamily 2, group C, member 1 isof... 114 1e-25
gi|116284373 peroxisome proliferative activated receptor gamma i... 114 2e-25
gi|20336229 peroxisome proliferative activated receptor gamma is... 114 2e-25
gi|116284368 peroxisome proliferative activated receptor gamma i... 114 2e-25
gi|116284370 peroxisome proliferative activated receptor gamma i... 114 2e-25
gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo... 114 2e-25
gi|11415052 retinoid X receptor, beta [Homo sapiens] 113 3e-25
gi|14149746 nuclear receptor subfamily 2, group F, member 2 isof... 112 6e-25
gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens] 111 1e-24
>gi|19743905 RAR-related orphan receptor A isoform d [Homo sapiens]
Length = 468
Score = 957 bits (2473), Expect = 0.0
Identities = 468/468 (100%), Positives = 468/468 (100%)
Query: 1 MMYFVIAAMKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNC 60
MMYFVIAAMKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNC
Sbjct: 1 MMYFVIAAMKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNC 60
Query: 61 LIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQ 120
LIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQ
Sbjct: 61 LIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQ 120
Query: 121 PGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLD 180
PGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLD
Sbjct: 121 PGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLD 180
Query: 181 INGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREEL 240
INGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREEL
Sbjct: 181 INGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREEL 240
Query: 241 QQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVL 300
QQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVL
Sbjct: 241 QQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVL 300
Query: 301 LKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHL 360
LKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHL
Sbjct: 301 LKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHL 360
Query: 361 TEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVS 420
TEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVS
Sbjct: 361 TEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVS 420
Query: 421 TLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG 468
TLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
Sbjct: 421 TLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG 468
>gi|4506577 RAR-related orphan receptor A isoform c [Homo sapiens]
Length = 548
Score = 941 bits (2432), Expect = 0.0
Identities = 460/466 (98%), Positives = 462/466 (99%)
Query: 3 YFVIAAMKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLI 62
+ + A KAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLI
Sbjct: 83 FLLPALRKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLI 142
Query: 63 DRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPG 122
DRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPG
Sbjct: 143 DRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPG 202
Query: 123 EAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDIN 182
EAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDIN
Sbjct: 203 EAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDIN 262
Query: 183 GIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQ 242
GIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQ
Sbjct: 263 GIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQ 322
Query: 243 ITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLK 302
ITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLK
Sbjct: 323 ITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLK 382
Query: 303 AGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTE 362
AGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTE
Sbjct: 383 AGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTE 442
Query: 363 DEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTL 422
DEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTL
Sbjct: 443 DEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTL 502
Query: 423 RALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG 468
RALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
Sbjct: 503 RALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG 548
>gi|19743901 RAR-related orphan receptor A isoform b [Homo sapiens]
Length = 556
Score = 940 bits (2429), Expect = 0.0
Identities = 459/460 (99%), Positives = 459/460 (99%)
Query: 9 MKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRN 68
M AQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRN
Sbjct: 97 MNAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRN 156
Query: 69 RCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLT 128
RCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLT
Sbjct: 157 RCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLT 216
Query: 129 PTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEP 188
PTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEP
Sbjct: 217 PTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEP 276
Query: 189 ICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTF 248
ICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTF
Sbjct: 277 ICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTF 336
Query: 249 LQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEV 308
LQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEV
Sbjct: 337 LQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEV 396
Query: 309 VFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALF 368
VFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALF
Sbjct: 397 VFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALF 456
Query: 369 SAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGR 428
SAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGR
Sbjct: 457 SAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGR 516
Query: 429 HTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG 468
HTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
Sbjct: 517 HTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG 556
>gi|19743903 RAR-related orphan receptor A isoform a [Homo sapiens]
Length = 523
Score = 937 bits (2421), Expect = 0.0
Identities = 457/458 (99%), Positives = 458/458 (100%)
Query: 11 AQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRC 70
+QIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRC
Sbjct: 66 SQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRC 125
Query: 71 QHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPT 130
QHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPT
Sbjct: 126 QHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPT 185
Query: 131 YNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPIC 190
YNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPIC
Sbjct: 186 YNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPIC 245
Query: 191 DYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQ 250
DYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQ
Sbjct: 246 DYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQ 305
Query: 251 EEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVF 310
EEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVF
Sbjct: 306 EEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVF 365
Query: 311 IRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSA 370
IRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSA
Sbjct: 366 IRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSA 425
Query: 371 FVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHT 430
FVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHT
Sbjct: 426 FVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHT 485
Query: 431 EKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG 468
EKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
Sbjct: 486 EKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG 523
>gi|19743907 RAR-related orphan receptor B [Homo sapiens]
Length = 459
Score = 585 bits (1508), Expect = e-167
Identities = 292/459 (63%), Positives = 354/459 (77%), Gaps = 14/459 (3%)
Query: 9 MKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRN 68
M+AQIE+IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQ+NA+YSCPRQ+NCLIDRT+RN
Sbjct: 1 MRAQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRN 60
Query: 69 RCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLT 128
RCQHCRLQKCLA+GMSRDAVKFGRMSKKQRDSLYAEVQKH+ Q+ Q QQQ GEAE L
Sbjct: 61 RCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQ-QRLQEQRQQQSGEAEALA 119
Query: 129 PTYNIS-ANGLTELHDDLSN-YIDGHTPEGSKADSAVSSFYLDI---QPSPDQSGLDING 183
Y+ S +NGL+ L+++ S Y +GH + K++ Y ++ QPSPDQSGLD+ G
Sbjct: 120 RVYSSSISNGLSNLNNETSGTYANGHVIDLPKSEG-----YYNVDSGQPSPDQSGLDMTG 174
Query: 184 IKP---EPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREEL 240
IK EPI D T F Y SF NG+ +P ++M E++ +AQNI KSHLETCQY EEL
Sbjct: 175 IKQIKQEPIYDLTSVPNLFTYSSFNNGQLAPGITMTEIDRIAQNIIKSHLETCQYTMEEL 234
Query: 241 QQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVL 300
Q+ WQT EEI+ YQ+K RE +WQ CAI+IT AIQYVVEFAKRI GFMELCQNDQI+L
Sbjct: 235 HQLAWQTHTYEEIKAYQSKSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILL 294
Query: 301 LKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHL 360
LK+G LEVV +RMCRAF+ NNTV F+GKY +FK+LG +D ++ F+F K+LCS+ L
Sbjct: 295 LKSGCLEVVLVRMCRAFNPLNNTVLFEGKYGGMQMFKALGSDDLVNEAFDFAKNLCSLQL 354
Query: 361 TEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVS 420
TE+EIALFS+ VL+S DR+WL E K++KLQ+KI ALQHV+QKNH +D L KLI K+
Sbjct: 355 TEEEIALFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQHVIQKNHLDDETLAKLIAKIP 414
Query: 421 TLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSE 459
T+ A+C H EKL FK +P+IV FPPLYKELF +
Sbjct: 415 TITAVCNLHGEKLQVFKQSHPEIVNTLFPPLYKELFNPD 453
>gi|48255918 RAR-related orphan receptor C isoform b [Homo sapiens]
Length = 497
Score = 458 bits (1178), Expect = e-129
Identities = 243/492 (49%), Positives = 318/492 (64%), Gaps = 41/492 (8%)
Query: 9 MKAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRN 68
M+ QIE+IPCKICGDKSSGIHYGVITCEGCKGFFRRSQ+ NA YSC RQ+NC IDRTSRN
Sbjct: 1 MRTQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRN 60
Query: 69 RCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQ---------- 118
RCQHCRLQKCLA+GMSRDAVKFGRMSKKQRDSL+AEVQK Q+QQ+ +
Sbjct: 61 RCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGA 120
Query: 119 ---------------QQPGEAEPLTPTYNISANGLTELHDDLSNYIDG------------ 151
Q P + P P + GL + +Y +
Sbjct: 121 QGADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAKAGLNGASCH 180
Query: 152 --HTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGET 209
++PE KA+ S + Q +PD+ GL + + + + SF +
Sbjct: 181 LEYSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELGQGPDSYGSPSFRSTPE 240
Query: 210 SPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCA 269
+P S+ E+EHL Q++ KS+ ETCQ E+L + F +EE+ YQ K MW+ CA
Sbjct: 241 APYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCA 300
Query: 270 IKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGK 329
+TEAIQYVVEFAKR+ GFMELCQNDQIVLLKAG++EVV +RMCRA+++ N TV+F+GK
Sbjct: 301 HHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGK 360
Query: 330 YASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEK 389
Y ++F++LGC + IS +F+F SL ++H +EDEIAL++A VL++A R LQEK K+E+
Sbjct: 361 YGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQ 420
Query: 390 LQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFP 449
LQ ++LA H L K HR+ IL KL K LR+LC +H E+L F+ ++P +V+ FP
Sbjct: 421 LQYNLELAFHHHLCKTHRQ-SILAKLPPK-GKLRSLCSQHVERLQIFQHLHPIVVQAAFP 478
Query: 450 PLYKELFTSEFE 461
PLYKELF++E E
Sbjct: 479 PLYKELFSTETE 490
>gi|19743909 RAR-related orphan receptor C isoform a [Homo sapiens]
Length = 518
Score = 456 bits (1173), Expect = e-128
Identities = 245/499 (49%), Positives = 322/499 (64%), Gaps = 44/499 (8%)
Query: 5 VIAAMK---AQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCL 61
++AA K +QIE+IPCKICGDKSSGIHYGVITCEGCKGFFRRSQ+ NA YSC RQ+NC
Sbjct: 15 LLAAKKTHTSQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCP 74
Query: 62 IDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQ--- 118
IDRTSRNRCQHCRLQKCLA+GMSRDAVKFGRMSKKQRDSL+AEVQK Q+QQ+ +
Sbjct: 75 IDRTSRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVV 134
Query: 119 ----------------------QQPGEAEPLTPTYNISANGLTELHDDLSNYIDG----- 151
Q P + P P + GL + +Y +
Sbjct: 135 KTPPAGAQGADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAKAG 194
Query: 152 ---------HTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYC 202
++PE KA+ S + Q +PD+ GL + + + +
Sbjct: 195 LNGASCHLEYSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELGQGPDSYGSP 254
Query: 203 SFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQRE 262
SF + +P S+ E+EHL Q++ KS+ ETCQ E+L + F +EE+ YQ K
Sbjct: 255 SFRSTPEAPYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMW 314
Query: 263 VMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNN 322
MW+ CA +TEAIQYVVEFAKR+ GFMELCQNDQIVLLKAG++EVV +RMCRA+++ N
Sbjct: 315 EMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNR 374
Query: 323 TVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQ 382
TV+F+GKY ++F++LGC + IS +F+F SL ++H +EDEIAL++A VL++A R LQ
Sbjct: 375 TVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQ 434
Query: 383 EKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPD 442
EK K+E+LQ ++LA H L K HR+ IL KL K LR+LC +H E+L F+ ++P
Sbjct: 435 EKRKVEQLQYNLELAFHHHLCKTHRQ-SILAKLPPK-GKLRSLCSQHVERLQIFQHLHPI 492
Query: 443 IVRLHFPPLYKELFTSEFE 461
+V+ FPPLYKELF++E E
Sbjct: 493 VVQAAFPPLYKELFSTETE 511
>gi|224177493 nuclear receptor subfamily 1, group D, member 2
isoform 2 [Homo sapiens]
Length = 504
Score = 143 bits (360), Expect = 4e-34
Identities = 77/182 (42%), Positives = 120/182 (65%), Gaps = 2/182 (1%)
Query: 258 NKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAF 317
+K +W+ ++ T A++ VVEFAKRI GF +L Q+DQ+ LLKAG+ EV+ +R F
Sbjct: 320 HKSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLF 379
Query: 318 DSQNNTVYF-DGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSA 376
D++ TV F GK S D S+G D ++ +FEF + L ++ L+++E++LF+A VL+SA
Sbjct: 380 DAKERTVTFLSGKKYSVDDLHSMGAGDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSA 439
Query: 377 DRSWLQEKVKIEKLQQKIQLALQHVLQKNH-REDGILTKLICKVSTLRALCGRHTEKLMA 435
DRS ++ +E LQ+ + AL+ ++ KNH E I TKL+ K+ LR+L H+E+L+A
Sbjct: 440 DRSGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLA 499
Query: 436 FK 437
FK
Sbjct: 500 FK 501
Score = 124 bits (312), Expect = 1e-28
Identities = 59/109 (54%), Positives = 75/109 (68%), Gaps = 4/109 (3%)
Query: 15 IIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYS-CPRQKNCLIDRTSRNRCQHC 73
++ CK+CGD +SG HYGV CEGCKGFFRRS Q N Y C + +NC I R +RNRCQ C
Sbjct: 25 VLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQC 84
Query: 74 RLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQ---KHRMQQQQRDHQQ 119
R +KCL+VGMSRDAV+FGR+ K+++ + E+Q K M Q H Q
Sbjct: 85 RFKKCLSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQFSGHLQ 133
>gi|224177491 nuclear receptor subfamily 1, group D, member 2
isoform 1 [Homo sapiens]
Length = 579
Score = 143 bits (360), Expect = 4e-34
Identities = 77/182 (42%), Positives = 120/182 (65%), Gaps = 2/182 (1%)
Query: 258 NKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAF 317
+K +W+ ++ T A++ VVEFAKRI GF +L Q+DQ+ LLKAG+ EV+ +R F
Sbjct: 395 HKSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLF 454
Query: 318 DSQNNTVYF-DGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSA 376
D++ TV F GK S D S+G D ++ +FEF + L ++ L+++E++LF+A VL+SA
Sbjct: 455 DAKERTVTFLSGKKYSVDDLHSMGAGDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSA 514
Query: 377 DRSWLQEKVKIEKLQQKIQLALQHVLQKNH-REDGILTKLICKVSTLRALCGRHTEKLMA 435
DRS ++ +E LQ+ + AL+ ++ KNH E I TKL+ K+ LR+L H+E+L+A
Sbjct: 515 DRSGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLA 574
Query: 436 FK 437
FK
Sbjct: 575 FK 576
Score = 124 bits (312), Expect = 1e-28
Identities = 59/109 (54%), Positives = 75/109 (68%), Gaps = 4/109 (3%)
Query: 15 IIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYS-CPRQKNCLIDRTSRNRCQHC 73
++ CK+CGD +SG HYGV CEGCKGFFRRS Q N Y C + +NC I R +RNRCQ C
Sbjct: 100 VLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQC 159
Query: 74 RLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQ---KHRMQQQQRDHQQ 119
R +KCL+VGMSRDAV+FGR+ K+++ + E+Q K M Q H Q
Sbjct: 160 RFKKCLSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQFSGHLQ 208
>gi|189491739 nuclear receptor subfamily 2, group C, member 1
isoform a [Homo sapiens]
Length = 603
Score = 132 bits (333), Expect = 5e-31
Identities = 129/481 (26%), Positives = 217/481 (45%), Gaps = 71/481 (14%)
Query: 18 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 77
C +CGDK+SG HYG +TCEGCKGFF+RS + N YSC K+C+I++ RNRCQ+CRLQ+
Sbjct: 113 CVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQR 172
Query: 78 CLAVGMSRDAVKFGR----MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEP--LTPTY 131
C+A GM +D+V+ R +S+++ + A +K +++ R P A P +T +
Sbjct: 173 CIAFGMKQDSVQCERKPIEVSREKSSNCAASTEKIYIRKDLR----SPLTATPTFVTDSE 228
Query: 132 NISANGLTELHDDLSNYIDGHTPEGSKADSAV-------------SSFYLDIQPSPDQSG 178
+ + GL D +++ H P G K +SAV S ++ S G
Sbjct: 229 STRSTGLL----DSGMFMNIH-PSGVKTESAVLMTSDKAESCQGDLSTLANVVTSLANLG 283
Query: 179 --LDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQY- 235
D++ E + ++ C F +T+ VS A + LA+ ++ CQ
Sbjct: 284 KTKDLSQNSNEMSMIESLSNDDTSLCEFQEMQTNGDVSRA-FDTLAKALNPGESTACQSS 342
Query: 236 ---LREELQQITWQTFLQEEIENYQNKQREVMWQL-CAIKITEA--------IQYVVEFA 283
+ + IT + + NY K+ ++ A ++T + Y+ E A
Sbjct: 343 VAGMEGSVHLITGDSSI-----NYTEKEGPLLSDSHVAFRLTMPSPMPEYLNVHYIGESA 397
Query: 284 KR-----------IDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQN---------NT 323
R I F L Q + I L+KA E+ + + + + N N
Sbjct: 398 SRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNVATILATFVNC 457
Query: 324 VYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQE 383
++ + + + I + EF S+ + + E A A VL S D L+
Sbjct: 458 LHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVLFSPDHPSLEN 517
Query: 384 KVKIEKLQQKIQLALQHVLQKNHREDGI-LTKLICKVSTLRALCGRHTEKLMAFKAIYPD 442
+IEK Q+K + Q + K + +D L++L+ ++ LR + TE+L FK + +
Sbjct: 518 MEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEELF-FKGLIGN 576
Query: 443 I 443
I
Sbjct: 577 I 577
>gi|13430848 nuclear receptor subfamily 1, group D, member 1 [Homo
sapiens]
Length = 614
Score = 128 bits (321), Expect = 1e-29
Identities = 70/176 (39%), Positives = 112/176 (63%), Gaps = 2/176 (1%)
Query: 264 MWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNT 323
+W+ ++ T A++ VVEFAK I GF +L Q+DQ+ LLKAG+ EV+ +R F+ ++ T
Sbjct: 435 IWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQT 494
Query: 324 VYFDGKYA-SPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQ 382
V F + S ++G D +S +F+F + L S+ LTE+E+ LF+A VL+SADRS ++
Sbjct: 495 VMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGME 554
Query: 383 EKVKIEKLQQKIQLALQHVLQKNH-REDGILTKLICKVSTLRALCGRHTEKLMAFK 437
+E+LQ+ + AL+ ++ KN E TKL+ K+ LR L H+EKL++F+
Sbjct: 555 NSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKLLSFR 610
Score = 127 bits (318), Expect = 3e-29
Identities = 59/113 (52%), Positives = 76/113 (67%), Gaps = 1/113 (0%)
Query: 15 IIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYS-CPRQKNCLIDRTSRNRCQHC 73
++ CK+CGD +SG HYGV CEGCKGFFRRS Q N Y C + +NC I R +RNRCQ C
Sbjct: 129 VLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQQC 188
Query: 74 RLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEP 126
R +KCL+VGMSRDAV+FGR+ K+++ + AE+Q + Q P E P
Sbjct: 189 RFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETSP 241
>gi|45545405 nuclear receptor subfamily 5, group A, member 2 isoform
1 [Homo sapiens]
Length = 541
Score = 124 bits (311), Expect = 2e-28
Identities = 113/450 (25%), Positives = 192/450 (42%), Gaps = 33/450 (7%)
Query: 18 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 77
C +CGDK SG HYG++TCE CKGFF+R+ Q+N Y+C +NC ID+T R RC +CR QK
Sbjct: 86 CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQK 145
Query: 78 CLAVGMSRDAV----------KFGRMSK-----KQRDSLYAEVQKHRMQQQQRDHQQQPG 122
CL+VGM +AV KFG M K KQ+ +++ + Q P
Sbjct: 146 CLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPS 205
Query: 123 EAEPLTPTYNI--SANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLD 180
+ + NI ++ GL H L +P + S + +Q
Sbjct: 206 DLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFP 265
Query: 181 INGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREEL 240
IK E YT + S+ ++ T S A + HL + K + E
Sbjct: 266 SRAIKSEYPDPYTSSPESIMGYSYM--DSYQTSSPASIPHLILELLKCEPD------EPQ 317
Query: 241 QQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVL 300
Q +LQ+E N ++ + L + + +VE+A+ F EL +DQ+ L
Sbjct: 318 VQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKL 377
Query: 301 LKAGSLEVVFIRMC--RAFDSQNNTVYF-DGKYASPDVFKSLG---CEDFISFVFEFGKS 354
L+ E++ + + + +++ G+ + S + +S E
Sbjct: 378 LQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAK 437
Query: 355 LCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNH-REDGILT 413
L S+ + E VL S D L+ +E +Q+++ AL N+ ++
Sbjct: 438 LRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFG 497
Query: 414 KLICKVSTLRALCGRHTEKLMAFKAIYPDI 443
+L+ ++ +RA+ E+ + +K + D+
Sbjct: 498 QLLLRLPEIRAI-SMQAEEYLYYKHLNGDV 526
>gi|4504343 nuclear receptor subfamily 5, group A, member 2 isoform
2 [Homo sapiens]
Length = 495
Score = 124 bits (311), Expect = 2e-28
Identities = 113/450 (25%), Positives = 192/450 (42%), Gaps = 33/450 (7%)
Query: 18 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 77
C +CGDK SG HYG++TCE CKGFF+R+ Q+N Y+C +NC ID+T R RC +CR QK
Sbjct: 40 CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQK 99
Query: 78 CLAVGMSRDAV----------KFGRMSK-----KQRDSLYAEVQKHRMQQQQRDHQQQPG 122
CL+VGM +AV KFG M K KQ+ +++ + Q P
Sbjct: 100 CLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPS 159
Query: 123 EAEPLTPTYNI--SANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLD 180
+ + NI ++ GL H L +P + S + +Q
Sbjct: 160 DLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFP 219
Query: 181 INGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREEL 240
IK E YT + S+ ++ T S A + HL + K + E
Sbjct: 220 SRAIKSEYPDPYTSSPESIMGYSYM--DSYQTSSPASIPHLILELLKCEPD------EPQ 271
Query: 241 QQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVL 300
Q +LQ+E N ++ + L + + +VE+A+ F EL +DQ+ L
Sbjct: 272 VQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKL 331
Query: 301 LKAGSLEVVFIRMC--RAFDSQNNTVYF-DGKYASPDVFKSLG---CEDFISFVFEFGKS 354
L+ E++ + + + +++ G+ + S + +S E
Sbjct: 332 LQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAK 391
Query: 355 LCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNH-REDGILT 413
L S+ + E VL S D L+ +E +Q+++ AL N+ ++
Sbjct: 392 LRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFG 451
Query: 414 KLICKVSTLRALCGRHTEKLMAFKAIYPDI 443
+L+ ++ +RA+ E+ + +K + D+
Sbjct: 452 QLLLRLPEIRAI-SMQAEEYLYYKHLNGDV 480
>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
Length = 443
Score = 122 bits (307), Expect = 5e-28
Identities = 52/81 (64%), Positives = 64/81 (79%)
Query: 17 PCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQ 76
PC +C DKSSG HYGV +CEGCKGFFRRS Q N Y+C R KNC+I++ +RNRCQ+CRLQ
Sbjct: 78 PCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQ 137
Query: 77 KCLAVGMSRDAVKFGRMSKKQ 97
KC VGMS++AV+ R KK+
Sbjct: 138 KCFEVGMSKEAVRNDRNKKKK 158
Score = 94.4 bits (233), Expect = 2e-19
Identities = 67/241 (27%), Positives = 117/241 (48%), Gaps = 12/241 (4%)
Query: 217 ELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAI 276
+LE L +SK+H ET L + L + T + ++ +W + T+ I
Sbjct: 174 QLEELITKVSKAHQETFPSLCQ-LGKYTTNSSADHRVQLDLG-----LWDKFSELATKCI 227
Query: 277 QYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYF-DGKYASPDV 335
+VEFAKR+ GF L DQI LLKA L+++ +R+C + + +T+ F DG +
Sbjct: 228 IKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQ 287
Query: 336 FKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQ 395
+ G VF F L + + + E L SA L+ DR L+E K++KLQ+ +
Sbjct: 288 MHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLL 347
Query: 396 LALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKE 454
AL+ + ++ + + +++ K++ LR + + E+ + K P PPL +E
Sbjct: 348 EALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPG----PMPPLIRE 403
Query: 455 L 455
+
Sbjct: 404 M 404
>gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]
Length = 454
Score = 122 bits (307), Expect = 5e-28
Identities = 52/81 (64%), Positives = 64/81 (79%)
Query: 17 PCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQ 76
PC +C DKSSG HYGV +CEGCKGFFRRS Q N Y+C R KNC+I++ +RNRCQ+CRLQ
Sbjct: 89 PCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQ 148
Query: 77 KCLAVGMSRDAVKFGRMSKKQ 97
KC VGMS++AV+ R KK+
Sbjct: 149 KCFEVGMSKEAVRNDRNKKKK 169
Score = 94.4 bits (233), Expect = 2e-19
Identities = 67/241 (27%), Positives = 117/241 (48%), Gaps = 12/241 (4%)
Query: 217 ELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAI 276
+LE L +SK+H ET L + L + T + ++ +W + T+ I
Sbjct: 185 QLEELITKVSKAHQETFPSLCQ-LGKYTTNSSADHRVQLDLG-----LWDKFSELATKCI 238
Query: 277 QYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYF-DGKYASPDV 335
+VEFAKR+ GF L DQI LLKA L+++ +R+C + + +T+ F DG +
Sbjct: 239 IKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQ 298
Query: 336 FKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQ 395
+ G VF F L + + + E L SA L+ DR L+E K++KLQ+ +
Sbjct: 299 MHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLL 358
Query: 396 LALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKE 454
AL+ + ++ + + +++ K++ LR + + E+ + K P PPL +E
Sbjct: 359 EALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPG----PMPPLIRE 414
Query: 455 L 455
+
Sbjct: 415 M 415
>gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens]
Length = 448
Score = 122 bits (305), Expect = 9e-28
Identities = 54/100 (54%), Positives = 69/100 (69%)
Query: 17 PCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQ 76
PC +C DKSSG HYGV CEGCKGFFRRS Q N Y+C R KNC+I++ +RNRCQ+CRLQ
Sbjct: 80 PCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQ 139
Query: 77 KCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRD 116
KC VGMS+++V+ R KK+ S + + M + D
Sbjct: 140 KCFEVGMSKESVRNDRNKKKKETSKQECTESYEMTAELDD 179
Score = 100 bits (250), Expect = 2e-21
Identities = 68/242 (28%), Positives = 121/242 (50%), Gaps = 12/242 (4%)
Query: 216 AELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEA 275
AEL+ L + I K+H ET L + + T +++ + +W + T+
Sbjct: 175 AELDDLTEKIRKAHQETFPSLCQLGKYTT------NSSADHRVRLDLGLWDKFSELATKC 228
Query: 276 IQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYF-DGKYASPD 334
I +VEFAKR+ GF L DQI LLKA L+++ +R+C + + +T+ F DG +
Sbjct: 229 IIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRT 288
Query: 335 VFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKI 394
+ G VF F L + + + E L SA L+ DR L+E K++KLQ+ +
Sbjct: 289 QMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPL 348
Query: 395 QLALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYK 453
AL+ ++ ++ + + K++ K++ LR++ + E+++ K P PPL +
Sbjct: 349 LEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPG----SMPPLIQ 404
Query: 454 EL 455
E+
Sbjct: 405 EM 406
>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 120 bits (301), Expect = 3e-27
Identities = 51/81 (62%), Positives = 63/81 (77%)
Query: 17 PCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQ 76
PC +C DKSSG HYGV CEGCKGFFRRS Q N Y+C R KNC+I++ +RNRCQ+CRLQ
Sbjct: 87 PCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQ 146
Query: 77 KCLAVGMSRDAVKFGRMSKKQ 97
KC VGMS+++V+ R KK+
Sbjct: 147 KCFEVGMSKESVRNDRNKKKK 167
Score = 89.4 bits (220), Expect = 7e-18
Identities = 65/245 (26%), Positives = 117/245 (47%), Gaps = 20/245 (8%)
Query: 217 ELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVM----WQLCAIKI 272
E+ L + + K+H ET L + L + N ++QR + W +
Sbjct: 183 EVGELIEKVRKAHQETFPALCQ----------LGKYTTNNSSEQRVSLDIDLWDKFSELS 232
Query: 273 TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYF-DGKYA 331
T+ I VEFAK++ GF L DQI LLKA L+++ +R+C + + +T+ F DG
Sbjct: 233 TKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTL 292
Query: 332 SPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQ 391
+ + G VF F L + + + E L SA L+ DR L++ +++ LQ
Sbjct: 293 NRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQ 352
Query: 392 QKIQLALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPP 450
+ + AL+ +V ++ + K++ K++ LR++ + E+++ K P PP
Sbjct: 353 EPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPG----SMPP 408
Query: 451 LYKEL 455
L +E+
Sbjct: 409 LIQEM 413
>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
Length = 457
Score = 120 bits (301), Expect = 3e-27
Identities = 51/81 (62%), Positives = 63/81 (77%)
Query: 17 PCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQ 76
PC +C DKSSG HYGV CEGCKGFFRRS Q N Y+C R KNC+I++ +RNRCQ+CRLQ
Sbjct: 82 PCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQ 141
Query: 77 KCLAVGMSRDAVKFGRMSKKQ 97
KC VGMS+++V+ R KK+
Sbjct: 142 KCFEVGMSKESVRNDRNKKKK 162
Score = 89.4 bits (220), Expect = 7e-18
Identities = 65/245 (26%), Positives = 117/245 (47%), Gaps = 20/245 (8%)
Query: 217 ELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVM----WQLCAIKI 272
E+ L + + K+H ET L + L + N ++QR + W +
Sbjct: 178 EVGELIEKVRKAHQETFPALCQ----------LGKYTTNNSSEQRVSLDIDLWDKFSELS 227
Query: 273 TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYF-DGKYA 331
T+ I VEFAK++ GF L DQI LLKA L+++ +R+C + + +T+ F DG
Sbjct: 228 TKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTL 287
Query: 332 SPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQ 391
+ + G VF F L + + + E L SA L+ DR L++ +++ LQ
Sbjct: 288 NRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQ 347
Query: 392 QKIQLALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPP 450
+ + AL+ +V ++ + K++ K++ LR++ + E+++ K P PP
Sbjct: 348 EPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPG----SMPP 403
Query: 451 LYKEL 455
L +E+
Sbjct: 404 LIQEM 408
>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 120 bits (301), Expect = 3e-27
Identities = 51/81 (62%), Positives = 63/81 (77%)
Query: 17 PCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQ 76
PC +C DKSSG HYGV CEGCKGFFRRS Q N Y+C R KNC+I++ +RNRCQ+CRLQ
Sbjct: 87 PCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQ 146
Query: 77 KCLAVGMSRDAVKFGRMSKKQ 97
KC VGMS+++V+ R KK+
Sbjct: 147 KCFEVGMSKESVRNDRNKKKK 167
Score = 89.4 bits (220), Expect = 7e-18
Identities = 65/245 (26%), Positives = 117/245 (47%), Gaps = 20/245 (8%)
Query: 217 ELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVM----WQLCAIKI 272
E+ L + + K+H ET L + L + N ++QR + W +
Sbjct: 183 EVGELIEKVRKAHQETFPALCQ----------LGKYTTNNSSEQRVSLDIDLWDKFSELS 232
Query: 273 TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYF-DGKYA 331
T+ I VEFAK++ GF L DQI LLKA L+++ +R+C + + +T+ F DG
Sbjct: 233 TKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTL 292
Query: 332 SPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQ 391
+ + G VF F L + + + E L SA L+ DR L++ +++ LQ
Sbjct: 293 NRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQ 352
Query: 392 QKIQLALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPP 450
+ + AL+ +V ++ + K++ K++ LR++ + E+++ K P PP
Sbjct: 353 EPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPG----SMPP 408
Query: 451 LYKEL 455
L +E+
Sbjct: 409 LIQEM 413
>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
Length = 462
Score = 115 bits (289), Expect = 7e-26
Identities = 58/127 (45%), Positives = 79/127 (62%), Gaps = 16/127 (12%)
Query: 18 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 77
C ICGD+SSG HYGV +CEGCKGFF+R+ + + TY+C K+CLID+ RNRCQ+CR QK
Sbjct: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194
Query: 78 CLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGE--------AEPLTP 129
CLA+GM R+AV+ R K R+ ++ ++ ++ P E EP T
Sbjct: 195 CLAMGMKREAVQEERQRGKDRN-------ENEVESTSSANEDMPVERILEAELAVEPKTE 247
Query: 130 TYNISAN 136
TY + AN
Sbjct: 248 TY-VEAN 253
Score = 57.0 bits (136), Expect = 4e-08
Identities = 44/164 (26%), Positives = 78/164 (47%), Gaps = 3/164 (1%)
Query: 279 VVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMC-RAFDSQNNTVYFDGKYASPDVFK 337
+VE+AKRI F EL +DQ++LL+AG E++ R+ ++ + G + +
Sbjct: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAH 338
Query: 338 SLGCEDFISFVF-EFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQL 396
S G V E + M + + E+ A VL + D L ++E L++K+
Sbjct: 339 SAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYA 398
Query: 397 ALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAI 439
+L+ + K + G KL+ ++ LR++ + E L FK I
Sbjct: 399 SLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLI 442
>gi|189491766 nuclear receptor subfamily 2, group C, member 1
isoform c [Homo sapiens]
Length = 483
Score = 114 bits (286), Expect = 1e-25
Identities = 62/152 (40%), Positives = 94/152 (61%), Gaps = 15/152 (9%)
Query: 18 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 77
C +CGDK+SG HYG +TCEGCKGFF+RS + N YSC K+C+I++ RNRCQ+CRLQ+
Sbjct: 113 CVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQR 172
Query: 78 CLAVGMSRDAVKFGR----MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEP--LTPTY 131
C+A GM +D+V+ R +S+++ + A +K +++ R P A P +T +
Sbjct: 173 CIAFGMKQDSVQCERKPIEVSREKSSNCAASTEKIYIRKDLR----SPLTATPTFVTDSE 228
Query: 132 NISANGLTELHDDLSNYIDGHTPEGSKADSAV 163
+ + GL D +++ H P G K +SAV
Sbjct: 229 STRSTGLL----DSGMFMNIH-PSGVKTESAV 255
>gi|73808084 nuclear receptor subfamily 2, group C, member 1 isoform
b [Homo sapiens]
Length = 467
Score = 114 bits (286), Expect = 1e-25
Identities = 62/152 (40%), Positives = 94/152 (61%), Gaps = 15/152 (9%)
Query: 18 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 77
C +CGDK+SG HYG +TCEGCKGFF+RS + N YSC K+C+I++ RNRCQ+CRLQ+
Sbjct: 113 CVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQR 172
Query: 78 CLAVGMSRDAVKFGR----MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEP--LTPTY 131
C+A GM +D+V+ R +S+++ + A +K +++ R P A P +T +
Sbjct: 173 CIAFGMKQDSVQCERKPIEVSREKSSNCAASTEKIYIRKDLR----SPLTATPTFVTDSE 228
Query: 132 NISANGLTELHDDLSNYIDGHTPEGSKADSAV 163
+ + GL D +++ H P G K +SAV
Sbjct: 229 STRSTGLL----DSGMFMNIH-PSGVKTESAV 255
>gi|116284373 peroxisome proliferative activated receptor gamma
isoform 1 [Homo sapiens]
Length = 477
Score = 114 bits (284), Expect = 2e-25
Identities = 51/91 (56%), Positives = 67/91 (73%), Gaps = 3/91 (3%)
Query: 16 IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYS-CPRQKNCLIDRTSRNRCQHCR 74
I C++CGDK+SG HYGV CEGCKGFFRR+ + Y C NC I + SRN+CQ+CR
Sbjct: 109 IECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQYCR 166
Query: 75 LQKCLAVGMSRDAVKFGRMSKKQRDSLYAEV 105
QKCLAVGMS +A++FGRM + +++ L AE+
Sbjct: 167 FQKCLAVGMSHNAIRFGRMPQAEKEKLLAEI 197
Score = 92.8 bits (229), Expect = 6e-19
Identities = 63/212 (29%), Positives = 107/212 (50%), Gaps = 9/212 (4%)
Query: 251 EEIENYQNKQREV---MWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLE 307
+ I Q + +EV ++Q C + EA+Q + E+AK I GF+ L NDQ+ LLK G E
Sbjct: 265 KHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHE 324
Query: 308 VVFIRMCRAFDSQNNTVYFDGKYASPDVFKSL--GCEDFISFVFEFGKSLCSMHLTEDEI 365
+++ + + + + + + KSL DF+ FEF ++ L + ++
Sbjct: 325 IIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDL 384
Query: 366 ALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDG-ILTKLICKVSTLRA 424
A+F A +++S DR L IE +Q + AL+ L+ NH E + KL+ K++ LR
Sbjct: 385 AIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQ 444
Query: 425 LCGRHTEKLMAFKAIYPDIVRLHFPPLYKELF 456
+ H + L K D + LH PL +E++
Sbjct: 445 IVTEHVQLLQVIKKTETD-MSLH--PLLQEIY 473
>gi|20336229 peroxisome proliferative activated receptor gamma
isoform 2 [Homo sapiens]
Length = 505
Score = 114 bits (284), Expect = 2e-25
Identities = 51/91 (56%), Positives = 67/91 (73%), Gaps = 3/91 (3%)
Query: 16 IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYS-CPRQKNCLIDRTSRNRCQHCR 74
I C++CGDK+SG HYGV CEGCKGFFRR+ + Y C NC I + SRN+CQ+CR
Sbjct: 137 IECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQYCR 194
Query: 75 LQKCLAVGMSRDAVKFGRMSKKQRDSLYAEV 105
QKCLAVGMS +A++FGRM + +++ L AE+
Sbjct: 195 FQKCLAVGMSHNAIRFGRMPQAEKEKLLAEI 225
Score = 92.8 bits (229), Expect = 6e-19
Identities = 63/212 (29%), Positives = 107/212 (50%), Gaps = 9/212 (4%)
Query: 251 EEIENYQNKQREV---MWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLE 307
+ I Q + +EV ++Q C + EA+Q + E+AK I GF+ L NDQ+ LLK G E
Sbjct: 293 KHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHE 352
Query: 308 VVFIRMCRAFDSQNNTVYFDGKYASPDVFKSL--GCEDFISFVFEFGKSLCSMHLTEDEI 365
+++ + + + + + + KSL DF+ FEF ++ L + ++
Sbjct: 353 IIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDL 412
Query: 366 ALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDG-ILTKLICKVSTLRA 424
A+F A +++S DR L IE +Q + AL+ L+ NH E + KL+ K++ LR
Sbjct: 413 AIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQ 472
Query: 425 LCGRHTEKLMAFKAIYPDIVRLHFPPLYKELF 456
+ H + L K D + LH PL +E++
Sbjct: 473 IVTEHVQLLQVIKKTETD-MSLH--PLLQEIY 501
>gi|116284368 peroxisome proliferative activated receptor gamma
isoform 1 [Homo sapiens]
Length = 477
Score = 114 bits (284), Expect = 2e-25
Identities = 51/91 (56%), Positives = 67/91 (73%), Gaps = 3/91 (3%)
Query: 16 IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYS-CPRQKNCLIDRTSRNRCQHCR 74
I C++CGDK+SG HYGV CEGCKGFFRR+ + Y C NC I + SRN+CQ+CR
Sbjct: 109 IECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQYCR 166
Query: 75 LQKCLAVGMSRDAVKFGRMSKKQRDSLYAEV 105
QKCLAVGMS +A++FGRM + +++ L AE+
Sbjct: 167 FQKCLAVGMSHNAIRFGRMPQAEKEKLLAEI 197
Score = 92.8 bits (229), Expect = 6e-19
Identities = 63/212 (29%), Positives = 107/212 (50%), Gaps = 9/212 (4%)
Query: 251 EEIENYQNKQREV---MWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLE 307
+ I Q + +EV ++Q C + EA+Q + E+AK I GF+ L NDQ+ LLK G E
Sbjct: 265 KHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHE 324
Query: 308 VVFIRMCRAFDSQNNTVYFDGKYASPDVFKSL--GCEDFISFVFEFGKSLCSMHLTEDEI 365
+++ + + + + + + KSL DF+ FEF ++ L + ++
Sbjct: 325 IIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDL 384
Query: 366 ALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDG-ILTKLICKVSTLRA 424
A+F A +++S DR L IE +Q + AL+ L+ NH E + KL+ K++ LR
Sbjct: 385 AIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQ 444
Query: 425 LCGRHTEKLMAFKAIYPDIVRLHFPPLYKELF 456
+ H + L K D + LH PL +E++
Sbjct: 445 IVTEHVQLLQVIKKTETD-MSLH--PLLQEIY 473
>gi|116284370 peroxisome proliferative activated receptor gamma
isoform 1 [Homo sapiens]
Length = 477
Score = 114 bits (284), Expect = 2e-25
Identities = 51/91 (56%), Positives = 67/91 (73%), Gaps = 3/91 (3%)
Query: 16 IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYS-CPRQKNCLIDRTSRNRCQHCR 74
I C++CGDK+SG HYGV CEGCKGFFRR+ + Y C NC I + SRN+CQ+CR
Sbjct: 109 IECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQYCR 166
Query: 75 LQKCLAVGMSRDAVKFGRMSKKQRDSLYAEV 105
QKCLAVGMS +A++FGRM + +++ L AE+
Sbjct: 167 FQKCLAVGMSHNAIRFGRMPQAEKEKLLAEI 197
Score = 92.8 bits (229), Expect = 6e-19
Identities = 63/212 (29%), Positives = 107/212 (50%), Gaps = 9/212 (4%)
Query: 251 EEIENYQNKQREV---MWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLE 307
+ I Q + +EV ++Q C + EA+Q + E+AK I GF+ L NDQ+ LLK G E
Sbjct: 265 KHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHE 324
Query: 308 VVFIRMCRAFDSQNNTVYFDGKYASPDVFKSL--GCEDFISFVFEFGKSLCSMHLTEDEI 365
+++ + + + + + + KSL DF+ FEF ++ L + ++
Sbjct: 325 IIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDL 384
Query: 366 ALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDG-ILTKLICKVSTLRA 424
A+F A +++S DR L IE +Q + AL+ L+ NH E + KL+ K++ LR
Sbjct: 385 AIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQ 444
Query: 425 LCGRHTEKLMAFKAIYPDIVRLHFPPLYKELF 456
+ H + L K D + LH PL +E++
Sbjct: 445 IVTEHVQLLQVIKKTETD-MSLH--PLLQEIY 473
>gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo
sapiens]
Length = 423
Score = 114 bits (284), Expect = 2e-25
Identities = 50/82 (60%), Positives = 61/82 (74%)
Query: 16 IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRL 75
I C +CGDKSSG HYG TCEGCK FF+RS + N TY+C +NC ID+ RN+CQ+CRL
Sbjct: 84 IECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRL 143
Query: 76 QKCLAVGMSRDAVKFGRMSKKQ 97
+KCL VGM R+AV+ GRM Q
Sbjct: 144 KKCLKVGMRREAVQRGRMPPTQ 165
Score = 46.2 bits (108), Expect = 6e-05
Identities = 42/164 (25%), Positives = 74/164 (45%), Gaps = 4/164 (2%)
Query: 280 VEFAKRIDGFMELCQNDQIVLLKA--GSLEVVFIRMCRAFDSQNNTVYFDGKYASP-DVF 336
VE+A+ I F +L DQ+ LL+ L V+ C + G +ASP
Sbjct: 231 VEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSAD 290
Query: 337 KSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQL 396
+ + D I E + L ++H+ E + A VL ++D L + IE LQ+K Q
Sbjct: 291 RVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQC 350
Query: 397 ALQHVLQKNH-REDGILTKLICKVSTLRALCGRHTEKLMAFKAI 439
AL+ ++ + + KL+ ++ +LR + E+L + +
Sbjct: 351 ALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLV 394
>gi|11415052 retinoid X receptor, beta [Homo sapiens]
Length = 533
Score = 113 bits (283), Expect = 3e-25
Identities = 48/82 (58%), Positives = 61/82 (74%)
Query: 18 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 77
C ICGD+SSG HYGV +CEGCKGFF+R+ + + TYSC K+C +D+ RNRCQ+CR QK
Sbjct: 205 CAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQK 264
Query: 78 CLAVGMSRDAVKFGRMSKKQRD 99
CLA GM R+AV+ R K +D
Sbjct: 265 CLATGMKREAVQEERQRGKDKD 286
Score = 58.9 bits (141), Expect = 9e-09
Identities = 44/164 (26%), Positives = 79/164 (48%), Gaps = 3/164 (1%)
Query: 279 VVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMC-RAFDSQNNTVYFDGKYASPDVFK 337
+VE+AKRI F L +DQ++LL+AG E++ R+ D ++ + G + +
Sbjct: 350 LVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAH 409
Query: 338 SLGCEDFISFVF-EFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQL 396
S G V E + M + + E+ A +L + D L ++E L++K+
Sbjct: 410 SAGVGAIFDRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYA 469
Query: 397 ALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAI 439
+L+ + QK + G KL+ ++ LR++ + E L FK I
Sbjct: 470 SLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLI 513
>gi|14149746 nuclear receptor subfamily 2, group F, member 2 isoform
a [Homo sapiens]
Length = 414
Score = 112 bits (281), Expect = 6e-25
Identities = 50/86 (58%), Positives = 63/86 (73%)
Query: 12 QIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQ 71
Q + I C +CGDKSSG HYG TCEGCK FF+RS + N +Y+C +NC ID+ RN+CQ
Sbjct: 73 QQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQ 132
Query: 72 HCRLQKCLAVGMSRDAVKFGRMSKKQ 97
+CRL+KCL VGM R+AV+ GRM Q
Sbjct: 133 YCRLKKCLKVGMRREAVQRGRMPPTQ 158
Score = 45.4 bits (106), Expect = 1e-04
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 4/164 (2%)
Query: 280 VEFAKRIDGFMELCQNDQIVLLKA--GSLEVVFIRMCRAFDSQNNTVYFDGKYASP-DVF 336
VE+A+ I F +L DQ+ LL+ L V+ C + G +ASP
Sbjct: 224 VEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSAD 283
Query: 337 KSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQL 396
+ + D I E + L ++H+ E + A VL ++D L + +E LQ+K Q
Sbjct: 284 RVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQC 343
Query: 397 ALQHVLQKNH-REDGILTKLICKVSTLRALCGRHTEKLMAFKAI 439
AL+ ++ + + KL+ ++ +LR + E+L + +
Sbjct: 344 ALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLV 387
>gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
Length = 463
Score = 111 bits (278), Expect = 1e-24
Identities = 48/87 (55%), Positives = 63/87 (72%)
Query: 18 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 77
C ICGD+SSG HYGV +CEGCKGFF+R+ + + Y+C K+CLID+ RNRCQ+CR QK
Sbjct: 139 CAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQK 198
Query: 78 CLAVGMSRDAVKFGRMSKKQRDSLYAE 104
CL +GM R+AV+ R ++R AE
Sbjct: 199 CLVMGMKREAVQEERQRSRERAESEAE 225
Score = 60.8 bits (146), Expect = 2e-09
Identities = 48/188 (25%), Positives = 84/188 (44%), Gaps = 4/188 (2%)
Query: 255 NYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMC 314
N +N + + +C + +VE+AKRI F +L DQ++LL+AG E++
Sbjct: 257 NMENSTNDPVTNICHAADKQLFT-LVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFS 315
Query: 315 -RAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVF-EFGKSLCSMHLTEDEIALFSAFV 372
R+ Q+ + G + S G V E + M + + E+ A V
Sbjct: 316 HRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIV 375
Query: 373 LMSADRSWLQEKVKIEKLQQKIQLALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTE 431
L + D L ++E L++K+ L+ + QK + G KL+ ++ LR++ + E
Sbjct: 376 LFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLE 435
Query: 432 KLMAFKAI 439
L FK I
Sbjct: 436 HLFFFKLI 443
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.135 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,100,402
Number of Sequences: 37866
Number of extensions: 818479
Number of successful extensions: 3838
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 125
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 3414
Number of HSP's gapped (non-prelim): 306
length of query: 468
length of database: 18,247,518
effective HSP length: 106
effective length of query: 362
effective length of database: 14,233,722
effective search space: 5152607364
effective search space used: 5152607364
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.