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Search of human proteins with 19743903
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19743903 RAR-related orphan receptor A isoform a [Homo
sapiens]
(523 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19743903 RAR-related orphan receptor A isoform a [Homo sapiens] 1063 0.0
gi|19743905 RAR-related orphan receptor A isoform d [Homo sapiens] 937 0.0
gi|4506577 RAR-related orphan receptor A isoform c [Homo sapiens] 937 0.0
gi|19743901 RAR-related orphan receptor A isoform b [Homo sapiens] 937 0.0
gi|19743907 RAR-related orphan receptor B [Homo sapiens] 581 e-166
gi|19743909 RAR-related orphan receptor C isoform a [Homo sapiens] 471 e-133
gi|48255918 RAR-related orphan receptor C isoform b [Homo sapiens] 456 e-128
gi|224177493 nuclear receptor subfamily 1, group D, member 2 iso... 143 4e-34
gi|224177491 nuclear receptor subfamily 1, group D, member 2 iso... 143 4e-34
gi|189491739 nuclear receptor subfamily 2, group C, member 1 iso... 132 6e-31
gi|13430848 nuclear receptor subfamily 1, group D, member 1 [Hom... 131 2e-30
gi|45545405 nuclear receptor subfamily 5, group A, member 2 isof... 124 2e-28
gi|4504343 nuclear receptor subfamily 5, group A, member 2 isofo... 124 2e-28
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 124 3e-28
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 124 3e-28
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens] 122 6e-28
gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens] 122 6e-28
gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens] 122 1e-27
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens] 120 3e-27
gi|116284373 peroxisome proliferative activated receptor gamma i... 119 5e-27
gi|20336229 peroxisome proliferative activated receptor gamma is... 119 5e-27
gi|116284368 peroxisome proliferative activated receptor gamma i... 119 5e-27
gi|116284370 peroxisome proliferative activated receptor gamma i... 119 5e-27
gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo... 119 5e-27
gi|14149746 nuclear receptor subfamily 2, group F, member 2 isof... 119 9e-27
gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens] 119 9e-27
gi|4506755 retinoid X receptor, alpha [Homo sapiens] 115 7e-26
gi|189491766 nuclear receptor subfamily 2, group C, member 1 iso... 114 2e-25
gi|73808084 nuclear receptor subfamily 2, group C, member 1 isof... 114 2e-25
gi|11415052 retinoid X receptor, beta [Homo sapiens] 113 4e-25
>gi|19743903 RAR-related orphan receptor A isoform a [Homo sapiens]
Length = 523
Score = 1063 bits (2750), Expect = 0.0
Identities = 523/523 (100%), Positives = 523/523 (100%)
Query: 1 MESAPAAPDPAASEPGSSGADAAAGSRETPLNQESARKSEPPAPVRRQSYSSTSRGISVT 60
MESAPAAPDPAASEPGSSGADAAAGSRETPLNQESARKSEPPAPVRRQSYSSTSRGISVT
Sbjct: 1 MESAPAAPDPAASEPGSSGADAAAGSRETPLNQESARKSEPPAPVRRQSYSSTSRGISVT 60
Query: 61 KKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRT 120
KKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRT
Sbjct: 61 KKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRT 120
Query: 121 SRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAE 180
SRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAE
Sbjct: 121 SRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAE 180
Query: 181 PLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIK 240
PLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIK
Sbjct: 181 PLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIK 240
Query: 241 PEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITW 300
PEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITW
Sbjct: 241 PEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITW 300
Query: 301 QTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGS 360
QTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGS
Sbjct: 301 QTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGS 360
Query: 361 LEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEI 420
LEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEI
Sbjct: 361 LEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEI 420
Query: 421 ALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRAL 480
ALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRAL
Sbjct: 421 ALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRAL 480
Query: 481 CGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG 523
CGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
Sbjct: 481 CGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG 523
>gi|19743905 RAR-related orphan receptor A isoform d [Homo sapiens]
Length = 468
Score = 937 bits (2421), Expect = 0.0
Identities = 457/458 (99%), Positives = 458/458 (100%)
Query: 66 SQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRC 125
+QIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRC
Sbjct: 11 AQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRC 70
Query: 126 QHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPT 185
QHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPT
Sbjct: 71 QHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPT 130
Query: 186 YNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPIC 245
YNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPIC
Sbjct: 131 YNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPIC 190
Query: 246 DYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQ 305
DYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQ
Sbjct: 191 DYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQ 250
Query: 306 EEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVF 365
EEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVF
Sbjct: 251 EEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVF 310
Query: 366 IRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSA 425
IRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSA
Sbjct: 311 IRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSA 370
Query: 426 FVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHT 485
FVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHT
Sbjct: 371 FVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHT 430
Query: 486 EKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG 523
EKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
Sbjct: 431 EKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG 468
>gi|4506577 RAR-related orphan receptor A isoform c [Homo sapiens]
Length = 548
Score = 937 bits (2421), Expect = 0.0
Identities = 457/458 (99%), Positives = 458/458 (100%)
Query: 66 SQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRC 125
+QIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRC
Sbjct: 91 AQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRC 150
Query: 126 QHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPT 185
QHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPT
Sbjct: 151 QHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPT 210
Query: 186 YNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPIC 245
YNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPIC
Sbjct: 211 YNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPIC 270
Query: 246 DYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQ 305
DYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQ
Sbjct: 271 DYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQ 330
Query: 306 EEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVF 365
EEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVF
Sbjct: 331 EEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVF 390
Query: 366 IRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSA 425
IRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSA
Sbjct: 391 IRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSA 450
Query: 426 FVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHT 485
FVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHT
Sbjct: 451 FVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHT 510
Query: 486 EKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG 523
EKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
Sbjct: 511 EKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG 548
>gi|19743901 RAR-related orphan receptor A isoform b [Homo sapiens]
Length = 556
Score = 937 bits (2421), Expect = 0.0
Identities = 457/458 (99%), Positives = 458/458 (100%)
Query: 66 SQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRC 125
+QIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRC
Sbjct: 99 AQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRC 158
Query: 126 QHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPT 185
QHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPT
Sbjct: 159 QHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPT 218
Query: 186 YNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPIC 245
YNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPIC
Sbjct: 219 YNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPIC 278
Query: 246 DYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQ 305
DYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQ
Sbjct: 279 DYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQ 338
Query: 306 EEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVF 365
EEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVF
Sbjct: 339 EEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVF 398
Query: 366 IRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSA 425
IRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSA
Sbjct: 399 IRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSA 458
Query: 426 FVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHT 485
FVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHT
Sbjct: 459 FVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHT 518
Query: 486 EKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG 523
EKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
Sbjct: 519 EKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG 556
>gi|19743907 RAR-related orphan receptor B [Homo sapiens]
Length = 459
Score = 581 bits (1498), Expect = e-166
Identities = 290/457 (63%), Positives = 352/457 (77%), Gaps = 14/457 (3%)
Query: 66 SQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRC 125
+QIE+IPCKICGDKSSGIHYGVITCEGCKGFFRRSQQ+NA+YSCPRQ+NCLIDRT+RNRC
Sbjct: 3 AQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQNNASYSCPRQRNCLIDRTNRNRC 62
Query: 126 QHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPT 185
QHCRLQKCLA+GMSRDAVKFGRMSKKQRDSLYAEVQKH+ Q+ Q QQQ GEAE L
Sbjct: 63 QHCRLQKCLALGMSRDAVKFGRMSKKQRDSLYAEVQKHQ-QRLQEQRQQQSGEAEALARV 121
Query: 186 YNIS-ANGLTELHDDLSN-YIDGHTPEGSKADSAVSSFYLDI---QPSPDQSGLDINGIK 240
Y+ S +NGL+ L+++ S Y +GH + K++ Y ++ QPSPDQSGLD+ GIK
Sbjct: 122 YSSSISNGLSNLNNETSGTYANGHVIDLPKSEG-----YYNVDSGQPSPDQSGLDMTGIK 176
Query: 241 P---EPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQ 297
EPI D T F Y SF NG+ +P ++M E++ +AQNI KSHLETCQY EEL Q
Sbjct: 177 QIKQEPIYDLTSVPNLFTYSSFNNGQLAPGITMTEIDRIAQNIIKSHLETCQYTMEELHQ 236
Query: 298 ITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLK 357
+ WQT EEI+ YQ+K RE +WQ CAI+IT AIQYVVEFAKRI GFMELCQNDQI+LLK
Sbjct: 237 LAWQTHTYEEIKAYQSKSREALWQQCAIQITHAIQYVVEFAKRITGFMELCQNDQILLLK 296
Query: 358 AGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTE 417
+G LEVV +RMCRAF+ NNTV F+GKY +FK+LG +D ++ F+F K+LCS+ LTE
Sbjct: 297 SGCLEVVLVRMCRAFNPLNNTVLFEGKYGGMQMFKALGSDDLVNEAFDFAKNLCSLQLTE 356
Query: 418 DEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTL 477
+EIALFS+ VL+S DR+WL E K++KLQ+KI ALQHV+QKNH +D L KLI K+ T+
Sbjct: 357 EEIALFSSAVLISPDRAWLIEPRKVQKLQEKIYFALQHVIQKNHLDDETLAKLIAKIPTI 416
Query: 478 RALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSE 514
A+C H EKL FK +P+IV FPPLYKELF +
Sbjct: 417 TAVCNLHGEKLQVFKQSHPEIVNTLFPPLYKELFNPD 453
>gi|19743909 RAR-related orphan receptor C isoform a [Homo sapiens]
Length = 518
Score = 471 bits (1211), Expect = e-133
Identities = 251/508 (49%), Positives = 326/508 (64%), Gaps = 41/508 (8%)
Query: 48 QSYSSTSRGISVTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATY 107
Q SR + KKTHTSQIE+IPCKICGDKSSGIHYGVITCEGCKGFFRRSQ+ NA Y
Sbjct: 6 QRQHRASRELLAAKKTHTSQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAY 65
Query: 108 SCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQ 167
SC RQ+NC IDRTSRNRCQHCRLQKCLA+GMSRDAVKFGRMSKKQRDSL+AEVQK Q+
Sbjct: 66 SCTRQQNCPIDRTSRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQR 125
Query: 168 QQRDHQ-------------------------QQPGEAEPLTPTYNISANGLTELHDDLSN 202
QQ+ + Q P + P P + GL + +
Sbjct: 126 QQQQQEPVVKTPPAGAQGADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPS 185
Query: 203 YIDG--------------HTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYT 248
Y + ++PE KA+ S + Q +PD+ GL + + +
Sbjct: 186 YSNNLAKAGLNGASCHLEYSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELG 245
Query: 249 PASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEI 308
+ SF + +P S+ E+EHL Q++ KS+ ETCQ E+L + F +EE+
Sbjct: 246 QGPDSYGSPSFRSTPEAPYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEV 305
Query: 309 ENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRM 368
YQ K MW+ CA +TEAIQYVVEFAKR+ GFMELCQNDQIVLLKAG++EVV +RM
Sbjct: 306 TGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRM 365
Query: 369 CRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVL 428
CRA+++ N TV+F+GKY ++F++LGC + IS +F+F SL ++H +EDEIAL++A VL
Sbjct: 366 CRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVL 425
Query: 429 MSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKL 488
++A R LQEK K+E+LQ ++LA H L K HR+ IL KL K LR+LC +H E+L
Sbjct: 426 INAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQ-SILAKLPPK-GKLRSLCSQHVERL 483
Query: 489 MAFKAIYPDIVRLHFPPLYKELFTSEFE 516
F+ ++P +V+ FPPLYKELF++E E
Sbjct: 484 QIFQHLHPIVVQAAFPPLYKELFSTETE 511
>gi|48255918 RAR-related orphan receptor C isoform b [Homo sapiens]
Length = 497
Score = 456 bits (1172), Expect = e-128
Identities = 242/490 (49%), Positives = 317/490 (64%), Gaps = 41/490 (8%)
Query: 66 SQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRC 125
+QIE+IPCKICGDKSSGIHYGVITCEGCKGFFRRSQ+ NA YSC RQ+NC IDRTSRNRC
Sbjct: 3 TQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRC 62
Query: 126 QHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQ------------ 173
QHCRLQKCLA+GMSRDAVKFGRMSKKQRDSL+AEVQK Q+QQ+ +
Sbjct: 63 QHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGAQG 122
Query: 174 -------------QQPGEAEPLTPTYNISANGLTELHDDLSNYIDG-------------- 206
Q P + P P + GL + +Y +
Sbjct: 123 ADTLTYTLGLPDGQLPLGSSPDLPEASACPPGLLKASGSGPSYSNNLAKAGLNGASCHLE 182
Query: 207 HTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSP 266
++PE KA+ S + Q +PD+ GL + + + + SF + +P
Sbjct: 183 YSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELGQGPDSYGSPSFRSTPEAP 242
Query: 267 TVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIK 326
S+ E+EHL Q++ KS+ ETCQ E+L + F +EE+ YQ K MW+ CA
Sbjct: 243 YASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHH 302
Query: 327 ITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYA 386
+TEAIQYVVEFAKR+ GFMELCQNDQIVLLKAG++EVV +RMCRA+++ N TV+F+GKY
Sbjct: 303 LTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYG 362
Query: 387 SPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQ 446
++F++LGC + IS +F+F SL ++H +EDEIAL++A VL++A R LQEK K+E+LQ
Sbjct: 363 GMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQ 422
Query: 447 QKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPL 506
++LA H L K HR+ IL KL K LR+LC +H E+L F+ ++P +V+ FPPL
Sbjct: 423 YNLELAFHHHLCKTHRQ-SILAKLPPK-GKLRSLCSQHVERLQIFQHLHPIVVQAAFPPL 480
Query: 507 YKELFTSEFE 516
YKELF++E E
Sbjct: 481 YKELFSTETE 490
>gi|224177493 nuclear receptor subfamily 1, group D, member 2
isoform 2 [Homo sapiens]
Length = 504
Score = 143 bits (360), Expect = 4e-34
Identities = 77/182 (42%), Positives = 120/182 (65%), Gaps = 2/182 (1%)
Query: 313 NKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAF 372
+K +W+ ++ T A++ VVEFAKRI GF +L Q+DQ+ LLKAG+ EV+ +R F
Sbjct: 320 HKSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLF 379
Query: 373 DSQNNTVYF-DGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSA 431
D++ TV F GK S D S+G D ++ +FEF + L ++ L+++E++LF+A VL+SA
Sbjct: 380 DAKERTVTFLSGKKYSVDDLHSMGAGDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSA 439
Query: 432 DRSWLQEKVKIEKLQQKIQLALQHVLQKNH-REDGILTKLICKVSTLRALCGRHTEKLMA 490
DRS ++ +E LQ+ + AL+ ++ KNH E I TKL+ K+ LR+L H+E+L+A
Sbjct: 440 DRSGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLA 499
Query: 491 FK 492
FK
Sbjct: 500 FK 501
Score = 124 bits (312), Expect = 2e-28
Identities = 59/109 (54%), Positives = 75/109 (68%), Gaps = 4/109 (3%)
Query: 70 IIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYS-CPRQKNCLIDRTSRNRCQHC 128
++ CK+CGD +SG HYGV CEGCKGFFRRS Q N Y C + +NC I R +RNRCQ C
Sbjct: 25 VLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSIMRMNRNRCQQC 84
Query: 129 RLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQ---KHRMQQQQRDHQQ 174
R +KCL+VGMSRDAV+FGR+ K+++ + E+Q K M Q H Q
Sbjct: 85 RFKKCLSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQFSGHLQ 133
>gi|224177491 nuclear receptor subfamily 1, group D, member 2
isoform 1 [Homo sapiens]
Length = 579
Score = 143 bits (360), Expect = 4e-34
Identities = 77/182 (42%), Positives = 120/182 (65%), Gaps = 2/182 (1%)
Query: 313 NKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAF 372
+K +W+ ++ T A++ VVEFAKRI GF +L Q+DQ+ LLKAG+ EV+ +R F
Sbjct: 395 HKSGHEIWEEFSMSFTPAVKEVVEFAKRIPGFRDLSQHDQVNLLKAGTFEVLMVRFASLF 454
Query: 373 DSQNNTVYF-DGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSA 431
D++ TV F GK S D S+G D ++ +FEF + L ++ L+++E++LF+A VL+SA
Sbjct: 455 DAKERTVTFLSGKKYSVDDLHSMGAGDLLNSMFEFSEKLNALQLSDEEMSLFTAVVLVSA 514
Query: 432 DRSWLQEKVKIEKLQQKIQLALQHVLQKNH-REDGILTKLICKVSTLRALCGRHTEKLMA 490
DRS ++ +E LQ+ + AL+ ++ KNH E I TKL+ K+ LR+L H+E+L+A
Sbjct: 515 DRSGIENVNSVEALQETLIRALRTLIMKNHPNEASIFTKLLLKLPDLRSLNNMHSEELLA 574
Query: 491 FK 492
FK
Sbjct: 575 FK 576
Score = 129 bits (323), Expect = 9e-30
Identities = 71/180 (39%), Positives = 103/180 (57%), Gaps = 18/180 (10%)
Query: 3 SAPAAPDPAASEPGSSGADAAAGSRETPLNQE----SARKSEPPAPVRRQSYSSTSRGIS 58
S P++P+ + S+ + + + E L + S + S+ AP +S+S ++
Sbjct: 39 SVPSSPNSSNSDTNGNPKNGDLANIEGILKNDRIDCSMKTSKSSAPGMTKSHSGVTKFSG 98
Query: 59 VTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYS-CPRQKNCLI 117
+ ++ CK+CGD +SG HYGV CEGCKGFFRRS Q N Y C + +NC I
Sbjct: 99 M----------VLLCKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKKCLKNENCSI 148
Query: 118 DRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQ---KHRMQQQQRDHQQ 174
R +RNRCQ CR +KCL+VGMSRDAV+FGR+ K+++ + E+Q K M Q H Q
Sbjct: 149 MRMNRNRCQQCRFKKCLSVGMSRDAVRFGRIPKREKQRMLIEMQSAMKTMMNSQFSGHLQ 208
>gi|189491739 nuclear receptor subfamily 2, group C, member 1
isoform a [Homo sapiens]
Length = 603
Score = 132 bits (333), Expect = 6e-31
Identities = 129/481 (26%), Positives = 217/481 (45%), Gaps = 71/481 (14%)
Query: 73 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 132
C +CGDK+SG HYG +TCEGCKGFF+RS + N YSC K+C+I++ RNRCQ+CRLQ+
Sbjct: 113 CVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQR 172
Query: 133 CLAVGMSRDAVKFGR----MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEP--LTPTY 186
C+A GM +D+V+ R +S+++ + A +K +++ R P A P +T +
Sbjct: 173 CIAFGMKQDSVQCERKPIEVSREKSSNCAASTEKIYIRKDLR----SPLTATPTFVTDSE 228
Query: 187 NISANGLTELHDDLSNYIDGHTPEGSKADSAV-------------SSFYLDIQPSPDQSG 233
+ + GL D +++ H P G K +SAV S ++ S G
Sbjct: 229 STRSTGLL----DSGMFMNIH-PSGVKTESAVLMTSDKAESCQGDLSTLANVVTSLANLG 283
Query: 234 --LDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQY- 290
D++ E + ++ C F +T+ VS A + LA+ ++ CQ
Sbjct: 284 KTKDLSQNSNEMSMIESLSNDDTSLCEFQEMQTNGDVSRA-FDTLAKALNPGESTACQSS 342
Query: 291 ---LREELQQITWQTFLQEEIENYQNKQREVMWQL-CAIKITEA--------IQYVVEFA 338
+ + IT + + NY K+ ++ A ++T + Y+ E A
Sbjct: 343 VAGMEGSVHLITGDSSI-----NYTEKEGPLLSDSHVAFRLTMPSPMPEYLNVHYIGESA 397
Query: 339 KR-----------IDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQN---------NT 378
R I F L Q + I L+KA E+ + + + + N N
Sbjct: 398 SRLLFLSMHWALSIPSFQALGQENSISLVKAYWNELFTLGLAQCWQVMNVATILATFVNC 457
Query: 379 VYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQE 438
++ + + + I + EF S+ + + E A A VL S D L+
Sbjct: 458 LHNSLQQDKMSTERRKLLMEHIFKLQEFCNSMVKLCIDGYEYAYLKAIVLFSPDHPSLEN 517
Query: 439 KVKIEKLQQKIQLALQHVLQKNHREDGI-LTKLICKVSTLRALCGRHTEKLMAFKAIYPD 497
+IEK Q+K + Q + K + +D L++L+ ++ LR + TE+L FK + +
Sbjct: 518 MEQIEKFQEKAYVEFQDYITKTYPDDTYRLSRLLLRLPALRLMNATITEELF-FKGLIGN 576
Query: 498 I 498
I
Sbjct: 577 I 577
>gi|13430848 nuclear receptor subfamily 1, group D, member 1 [Homo
sapiens]
Length = 614
Score = 131 bits (329), Expect = 2e-30
Identities = 72/175 (41%), Positives = 100/175 (57%), Gaps = 9/175 (5%)
Query: 10 PAASEPGSSGADAAAGSRETPLNQESARKSEPPAP--VRRQSYSSTSRGISVTKKTHTSQ 67
P+ S+ GS + +++ S + S PP V + S S S + T +
Sbjct: 73 PSLSDDGSPSSSSSSSS-----SSSSFYNGSPPGSLQVAMEDSSRVSPSKSTSNITKLNG 127
Query: 68 IEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYS-CPRQKNCLIDRTSRNRCQ 126
+ ++ CK+CGD +SG HYGV CEGCKGFFRRS Q N Y C + +NC I R +RNRCQ
Sbjct: 128 MVLL-CKVCGDVASGFHYGVHACEGCKGFFRRSIQQNIQYKRCLKNENCSIVRINRNRCQ 186
Query: 127 HCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEP 181
CR +KCL+VGMSRDAV+FGR+ K+++ + AE+Q + Q P E P
Sbjct: 187 QCRFKKCLSVGMSRDAVRFGRIPKREKQRMLAEMQSAMNLANNQLSSQCPLETSP 241
Score = 128 bits (321), Expect = 1e-29
Identities = 70/176 (39%), Positives = 112/176 (63%), Gaps = 2/176 (1%)
Query: 319 MWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNT 378
+W+ ++ T A++ VVEFAK I GF +L Q+DQ+ LLKAG+ EV+ +R F+ ++ T
Sbjct: 435 IWEDFSMSFTPAVREVVEFAKHIPGFRDLSQHDQVTLLKAGTFEVLMVRFASLFNVKDQT 494
Query: 379 VYFDGKYA-SPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQ 437
V F + S ++G D +S +F+F + L S+ LTE+E+ LF+A VL+SADRS ++
Sbjct: 495 VMFLSRTTYSLQELGAMGMGDLLSAMFDFSEKLNSLALTEEELGLFTAVVLVSADRSGME 554
Query: 438 EKVKIEKLQQKIQLALQHVLQKNH-REDGILTKLICKVSTLRALCGRHTEKLMAFK 492
+E+LQ+ + AL+ ++ KN E TKL+ K+ LR L H+EKL++F+
Sbjct: 555 NSASVEQLQETLLRALRALVLKNRPLETSRFTKLLLKLPDLRTLNNMHSEKLLSFR 610
>gi|45545405 nuclear receptor subfamily 5, group A, member 2 isoform
1 [Homo sapiens]
Length = 541
Score = 124 bits (311), Expect = 2e-28
Identities = 113/450 (25%), Positives = 192/450 (42%), Gaps = 33/450 (7%)
Query: 73 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 132
C +CGDK SG HYG++TCE CKGFF+R+ Q+N Y+C +NC ID+T R RC +CR QK
Sbjct: 86 CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQK 145
Query: 133 CLAVGMSRDAV----------KFGRMSK-----KQRDSLYAEVQKHRMQQQQRDHQQQPG 177
CL+VGM +AV KFG M K KQ+ +++ + Q P
Sbjct: 146 CLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPS 205
Query: 178 EAEPLTPTYNI--SANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLD 235
+ + NI ++ GL H L +P + S + +Q
Sbjct: 206 DLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFP 265
Query: 236 INGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREEL 295
IK E YT + S+ ++ T S A + HL + K + E
Sbjct: 266 SRAIKSEYPDPYTSSPESIMGYSYM--DSYQTSSPASIPHLILELLKCEPD------EPQ 317
Query: 296 QQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVL 355
Q +LQ+E N ++ + L + + +VE+A+ F EL +DQ+ L
Sbjct: 318 VQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKL 377
Query: 356 LKAGSLEVVFIRMC--RAFDSQNNTVYF-DGKYASPDVFKSLG---CEDFISFVFEFGKS 409
L+ E++ + + + +++ G+ + S + +S E
Sbjct: 378 LQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAK 437
Query: 410 LCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNH-REDGILT 468
L S+ + E VL S D L+ +E +Q+++ AL N+ ++
Sbjct: 438 LRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFG 497
Query: 469 KLICKVSTLRALCGRHTEKLMAFKAIYPDI 498
+L+ ++ +RA+ E+ + +K + D+
Sbjct: 498 QLLLRLPEIRAI-SMQAEEYLYYKHLNGDV 526
>gi|4504343 nuclear receptor subfamily 5, group A, member 2 isoform
2 [Homo sapiens]
Length = 495
Score = 124 bits (311), Expect = 2e-28
Identities = 113/450 (25%), Positives = 192/450 (42%), Gaps = 33/450 (7%)
Query: 73 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 132
C +CGDK SG HYG++TCE CKGFF+R+ Q+N Y+C +NC ID+T R RC +CR QK
Sbjct: 40 CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQK 99
Query: 133 CLAVGMSRDAV----------KFGRMSK-----KQRDSLYAEVQKHRMQQQQRDHQQQPG 177
CL+VGM +AV KFG M K KQ+ +++ + Q P
Sbjct: 100 CLSVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPS 159
Query: 178 EAEPLTPTYNI--SANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLD 235
+ + NI ++ GL H L +P + S + +Q
Sbjct: 160 DLTISSAIQNIHSASKGLPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFP 219
Query: 236 INGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREEL 295
IK E YT + S+ ++ T S A + HL + K + E
Sbjct: 220 SRAIKSEYPDPYTSSPESIMGYSYM--DSYQTSSPASIPHLILELLKCEPD------EPQ 271
Query: 296 QQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVL 355
Q +LQ+E N ++ + L + + +VE+A+ F EL +DQ+ L
Sbjct: 272 VQAKIMAYLQQEQANRSKHEKLSTFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKL 331
Query: 356 LKAGSLEVVFIRMC--RAFDSQNNTVYF-DGKYASPDVFKSLG---CEDFISFVFEFGKS 409
L+ E++ + + + +++ G+ + S + +S E
Sbjct: 332 LQNCWSELLILDHIYRQVVHGKEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAK 391
Query: 410 LCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNH-REDGILT 468
L S+ + E VL S D L+ +E +Q+++ AL N+ ++
Sbjct: 392 LRSLQFDQREFVCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFG 451
Query: 469 KLICKVSTLRALCGRHTEKLMAFKAIYPDI 498
+L+ ++ +RA+ E+ + +K + D+
Sbjct: 452 QLLLRLPEIRAI-SMQAEEYLYYKHLNGDV 480
>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 124 bits (310), Expect = 3e-28
Identities = 63/139 (45%), Positives = 84/139 (60%), Gaps = 1/139 (0%)
Query: 15 PGSSGADAAAGSRETPLNQESARKSEPPAPVRRQSYSSTSRGISVTKKTHTSQIEII-PC 73
P G + G+ T +Q P+P ++ SS+S I + + I PC
Sbjct: 29 PPMLGGLSPPGALTTLQHQLPVSGYSTPSPATIETQSSSSEEIVPSPPSPPPLPRIYKPC 88
Query: 74 KICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKC 133
+C DKSSG HYGV CEGCKGFFRRS Q N Y+C R KNC+I++ +RNRCQ+CRLQKC
Sbjct: 89 FVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKC 148
Query: 134 LAVGMSRDAVKFGRMSKKQ 152
VGMS+++V+ R KK+
Sbjct: 149 FEVGMSKESVRNDRNKKKK 167
Score = 89.4 bits (220), Expect = 7e-18
Identities = 65/245 (26%), Positives = 117/245 (47%), Gaps = 20/245 (8%)
Query: 272 ELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVM----WQLCAIKI 327
E+ L + + K+H ET L + L + N ++QR + W +
Sbjct: 183 EVGELIEKVRKAHQETFPALCQ----------LGKYTTNNSSEQRVSLDIDLWDKFSELS 232
Query: 328 TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYF-DGKYA 386
T+ I VEFAK++ GF L DQI LLKA L+++ +R+C + + +T+ F DG
Sbjct: 233 TKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTL 292
Query: 387 SPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQ 446
+ + G VF F L + + + E L SA L+ DR L++ +++ LQ
Sbjct: 293 NRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQ 352
Query: 447 QKIQLALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPP 505
+ + AL+ +V ++ + K++ K++ LR++ + E+++ K P PP
Sbjct: 353 EPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPG----SMPP 408
Query: 506 LYKEL 510
L +E+
Sbjct: 409 LIQEM 413
>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 124 bits (310), Expect = 3e-28
Identities = 63/139 (45%), Positives = 84/139 (60%), Gaps = 1/139 (0%)
Query: 15 PGSSGADAAAGSRETPLNQESARKSEPPAPVRRQSYSSTSRGISVTKKTHTSQIEII-PC 73
P G + G+ T +Q P+P ++ SS+S I + + I PC
Sbjct: 29 PPMLGGLSPPGALTTLQHQLPVSGYSTPSPATIETQSSSSEEIVPSPPSPPPLPRIYKPC 88
Query: 74 KICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKC 133
+C DKSSG HYGV CEGCKGFFRRS Q N Y+C R KNC+I++ +RNRCQ+CRLQKC
Sbjct: 89 FVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKC 148
Query: 134 LAVGMSRDAVKFGRMSKKQ 152
VGMS+++V+ R KK+
Sbjct: 149 FEVGMSKESVRNDRNKKKK 167
Score = 89.4 bits (220), Expect = 7e-18
Identities = 65/245 (26%), Positives = 117/245 (47%), Gaps = 20/245 (8%)
Query: 272 ELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVM----WQLCAIKI 327
E+ L + + K+H ET L + L + N ++QR + W +
Sbjct: 183 EVGELIEKVRKAHQETFPALCQ----------LGKYTTNNSSEQRVSLDIDLWDKFSELS 232
Query: 328 TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYF-DGKYA 386
T+ I VEFAK++ GF L DQI LLKA L+++ +R+C + + +T+ F DG
Sbjct: 233 TKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTL 292
Query: 387 SPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQ 446
+ + G VF F L + + + E L SA L+ DR L++ +++ LQ
Sbjct: 293 NRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQ 352
Query: 447 QKIQLALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPP 505
+ + AL+ +V ++ + K++ K++ LR++ + E+++ K P PP
Sbjct: 353 EPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPG----SMPP 408
Query: 506 LYKEL 510
L +E+
Sbjct: 409 LIQEM 413
>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
Length = 443
Score = 122 bits (307), Expect = 6e-28
Identities = 52/81 (64%), Positives = 64/81 (79%)
Query: 72 PCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQ 131
PC +C DKSSG HYGV +CEGCKGFFRRS Q N Y+C R KNC+I++ +RNRCQ+CRLQ
Sbjct: 78 PCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQ 137
Query: 132 KCLAVGMSRDAVKFGRMSKKQ 152
KC VGMS++AV+ R KK+
Sbjct: 138 KCFEVGMSKEAVRNDRNKKKK 158
Score = 94.4 bits (233), Expect = 2e-19
Identities = 67/241 (27%), Positives = 117/241 (48%), Gaps = 12/241 (4%)
Query: 272 ELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAI 331
+LE L +SK+H ET L + L + T + ++ +W + T+ I
Sbjct: 174 QLEELITKVSKAHQETFPSLCQ-LGKYTTNSSADHRVQLDLG-----LWDKFSELATKCI 227
Query: 332 QYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYF-DGKYASPDV 390
+VEFAKR+ GF L DQI LLKA L+++ +R+C + + +T+ F DG +
Sbjct: 228 IKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQ 287
Query: 391 FKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQ 450
+ G VF F L + + + E L SA L+ DR L+E K++KLQ+ +
Sbjct: 288 MHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLL 347
Query: 451 LALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKE 509
AL+ + ++ + + +++ K++ LR + + E+ + K P PPL +E
Sbjct: 348 EALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPG----PMPPLIRE 403
Query: 510 L 510
+
Sbjct: 404 M 404
>gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]
Length = 454
Score = 122 bits (307), Expect = 6e-28
Identities = 52/81 (64%), Positives = 64/81 (79%)
Query: 72 PCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQ 131
PC +C DKSSG HYGV +CEGCKGFFRRS Q N Y+C R KNC+I++ +RNRCQ+CRLQ
Sbjct: 89 PCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQ 148
Query: 132 KCLAVGMSRDAVKFGRMSKKQ 152
KC VGMS++AV+ R KK+
Sbjct: 149 KCFEVGMSKEAVRNDRNKKKK 169
Score = 94.4 bits (233), Expect = 2e-19
Identities = 67/241 (27%), Positives = 117/241 (48%), Gaps = 12/241 (4%)
Query: 272 ELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAI 331
+LE L +SK+H ET L + L + T + ++ +W + T+ I
Sbjct: 185 QLEELITKVSKAHQETFPSLCQ-LGKYTTNSSADHRVQLDLG-----LWDKFSELATKCI 238
Query: 332 QYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYF-DGKYASPDV 390
+VEFAKR+ GF L DQI LLKA L+++ +R+C + + +T+ F DG +
Sbjct: 239 IKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQ 298
Query: 391 FKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQ 450
+ G VF F L + + + E L SA L+ DR L+E K++KLQ+ +
Sbjct: 299 MHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLL 358
Query: 451 LALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKE 509
AL+ + ++ + + +++ K++ LR + + E+ + K P PPL +E
Sbjct: 359 EALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPG----PMPPLIRE 414
Query: 510 L 510
+
Sbjct: 415 M 415
>gi|14916494 retinoic acid receptor, beta isoform 1 [Homo sapiens]
Length = 448
Score = 122 bits (305), Expect = 1e-27
Identities = 54/100 (54%), Positives = 69/100 (69%)
Query: 72 PCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQ 131
PC +C DKSSG HYGV CEGCKGFFRRS Q N Y+C R KNC+I++ +RNRCQ+CRLQ
Sbjct: 80 PCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMIYTCHRDKNCVINKVTRNRCQYCRLQ 139
Query: 132 KCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRD 171
KC VGMS+++V+ R KK+ S + + M + D
Sbjct: 140 KCFEVGMSKESVRNDRNKKKKETSKQECTESYEMTAELDD 179
Score = 100 bits (250), Expect = 2e-21
Identities = 68/242 (28%), Positives = 121/242 (50%), Gaps = 12/242 (4%)
Query: 271 AELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEA 330
AEL+ L + I K+H ET L + + T +++ + +W + T+
Sbjct: 175 AELDDLTEKIRKAHQETFPSLCQLGKYTT------NSSADHRVRLDLGLWDKFSELATKC 228
Query: 331 IQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYF-DGKYASPD 389
I +VEFAKR+ GF L DQI LLKA L+++ +R+C + + +T+ F DG +
Sbjct: 229 IIKIVEFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRT 288
Query: 390 VFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKI 449
+ G VF F L + + + E L SA L+ DR L+E K++KLQ+ +
Sbjct: 289 QMHNAGFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPL 348
Query: 450 QLALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYK 508
AL+ ++ ++ + + K++ K++ LR++ + E+++ K P PPL +
Sbjct: 349 LEALKIYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPG----SMPPLIQ 404
Query: 509 EL 510
E+
Sbjct: 405 EM 406
>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
Length = 457
Score = 120 bits (301), Expect = 3e-27
Identities = 51/81 (62%), Positives = 63/81 (77%)
Query: 72 PCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQ 131
PC +C DKSSG HYGV CEGCKGFFRRS Q N Y+C R KNC+I++ +RNRCQ+CRLQ
Sbjct: 82 PCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQ 141
Query: 132 KCLAVGMSRDAVKFGRMSKKQ 152
KC VGMS+++V+ R KK+
Sbjct: 142 KCFEVGMSKESVRNDRNKKKK 162
Score = 89.4 bits (220), Expect = 7e-18
Identities = 65/245 (26%), Positives = 117/245 (47%), Gaps = 20/245 (8%)
Query: 272 ELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVM----WQLCAIKI 327
E+ L + + K+H ET L + L + N ++QR + W +
Sbjct: 178 EVGELIEKVRKAHQETFPALCQ----------LGKYTTNNSSEQRVSLDIDLWDKFSELS 227
Query: 328 TEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYF-DGKYA 386
T+ I VEFAK++ GF L DQI LLKA L+++ +R+C + + +T+ F DG
Sbjct: 228 TKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTL 287
Query: 387 SPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQ 446
+ + G VF F L + + + E L SA L+ DR L++ +++ LQ
Sbjct: 288 NRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQ 347
Query: 447 QKIQLALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPP 505
+ + AL+ +V ++ + K++ K++ LR++ + E+++ K P PP
Sbjct: 348 EPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPG----SMPP 403
Query: 506 LYKEL 510
L +E+
Sbjct: 404 LIQEM 408
>gi|116284373 peroxisome proliferative activated receptor gamma
isoform 1 [Homo sapiens]
Length = 477
Score = 119 bits (299), Expect = 5e-27
Identities = 59/128 (46%), Positives = 84/128 (65%), Gaps = 6/128 (4%)
Query: 34 ESARKSEPPAPVRRQSYSSTSRGISVTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGC 93
+SA K EP +P YS ++ + + ++ + I C++CGDK+SG HYGV CEGC
Sbjct: 75 QSAIKVEPASP---PYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGC 131
Query: 94 KGFFRRSQQSNATYS-CPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQ 152
KGFFRR+ + Y C NC I + SRN+CQ+CR QKCLAVGMS +A++FGRM + +
Sbjct: 132 KGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAE 189
Query: 153 RDSLYAEV 160
++ L AE+
Sbjct: 190 KEKLLAEI 197
Score = 92.8 bits (229), Expect = 7e-19
Identities = 63/212 (29%), Positives = 107/212 (50%), Gaps = 9/212 (4%)
Query: 306 EEIENYQNKQREV---MWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLE 362
+ I Q + +EV ++Q C + EA+Q + E+AK I GF+ L NDQ+ LLK G E
Sbjct: 265 KHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHE 324
Query: 363 VVFIRMCRAFDSQNNTVYFDGKYASPDVFKSL--GCEDFISFVFEFGKSLCSMHLTEDEI 420
+++ + + + + + + KSL DF+ FEF ++ L + ++
Sbjct: 325 IIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDL 384
Query: 421 ALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDG-ILTKLICKVSTLRA 479
A+F A +++S DR L IE +Q + AL+ L+ NH E + KL+ K++ LR
Sbjct: 385 AIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQ 444
Query: 480 LCGRHTEKLMAFKAIYPDIVRLHFPPLYKELF 511
+ H + L K D + LH PL +E++
Sbjct: 445 IVTEHVQLLQVIKKTETD-MSLH--PLLQEIY 473
>gi|20336229 peroxisome proliferative activated receptor gamma
isoform 2 [Homo sapiens]
Length = 505
Score = 119 bits (299), Expect = 5e-27
Identities = 59/128 (46%), Positives = 84/128 (65%), Gaps = 6/128 (4%)
Query: 34 ESARKSEPPAPVRRQSYSSTSRGISVTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGC 93
+SA K EP +P YS ++ + + ++ + I C++CGDK+SG HYGV CEGC
Sbjct: 103 QSAIKVEPASP---PYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGC 159
Query: 94 KGFFRRSQQSNATYS-CPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQ 152
KGFFRR+ + Y C NC I + SRN+CQ+CR QKCLAVGMS +A++FGRM + +
Sbjct: 160 KGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAE 217
Query: 153 RDSLYAEV 160
++ L AE+
Sbjct: 218 KEKLLAEI 225
Score = 92.8 bits (229), Expect = 7e-19
Identities = 63/212 (29%), Positives = 107/212 (50%), Gaps = 9/212 (4%)
Query: 306 EEIENYQNKQREV---MWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLE 362
+ I Q + +EV ++Q C + EA+Q + E+AK I GF+ L NDQ+ LLK G E
Sbjct: 293 KHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHE 352
Query: 363 VVFIRMCRAFDSQNNTVYFDGKYASPDVFKSL--GCEDFISFVFEFGKSLCSMHLTEDEI 420
+++ + + + + + + KSL DF+ FEF ++ L + ++
Sbjct: 353 IIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDL 412
Query: 421 ALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDG-ILTKLICKVSTLRA 479
A+F A +++S DR L IE +Q + AL+ L+ NH E + KL+ K++ LR
Sbjct: 413 AIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQ 472
Query: 480 LCGRHTEKLMAFKAIYPDIVRLHFPPLYKELF 511
+ H + L K D + LH PL +E++
Sbjct: 473 IVTEHVQLLQVIKKTETD-MSLH--PLLQEIY 501
>gi|116284368 peroxisome proliferative activated receptor gamma
isoform 1 [Homo sapiens]
Length = 477
Score = 119 bits (299), Expect = 5e-27
Identities = 59/128 (46%), Positives = 84/128 (65%), Gaps = 6/128 (4%)
Query: 34 ESARKSEPPAPVRRQSYSSTSRGISVTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGC 93
+SA K EP +P YS ++ + + ++ + I C++CGDK+SG HYGV CEGC
Sbjct: 75 QSAIKVEPASP---PYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGC 131
Query: 94 KGFFRRSQQSNATYS-CPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQ 152
KGFFRR+ + Y C NC I + SRN+CQ+CR QKCLAVGMS +A++FGRM + +
Sbjct: 132 KGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAE 189
Query: 153 RDSLYAEV 160
++ L AE+
Sbjct: 190 KEKLLAEI 197
Score = 92.8 bits (229), Expect = 7e-19
Identities = 63/212 (29%), Positives = 107/212 (50%), Gaps = 9/212 (4%)
Query: 306 EEIENYQNKQREV---MWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLE 362
+ I Q + +EV ++Q C + EA+Q + E+AK I GF+ L NDQ+ LLK G E
Sbjct: 265 KHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHE 324
Query: 363 VVFIRMCRAFDSQNNTVYFDGKYASPDVFKSL--GCEDFISFVFEFGKSLCSMHLTEDEI 420
+++ + + + + + + KSL DF+ FEF ++ L + ++
Sbjct: 325 IIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDL 384
Query: 421 ALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDG-ILTKLICKVSTLRA 479
A+F A +++S DR L IE +Q + AL+ L+ NH E + KL+ K++ LR
Sbjct: 385 AIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQ 444
Query: 480 LCGRHTEKLMAFKAIYPDIVRLHFPPLYKELF 511
+ H + L K D + LH PL +E++
Sbjct: 445 IVTEHVQLLQVIKKTETD-MSLH--PLLQEIY 473
>gi|116284370 peroxisome proliferative activated receptor gamma
isoform 1 [Homo sapiens]
Length = 477
Score = 119 bits (299), Expect = 5e-27
Identities = 59/128 (46%), Positives = 84/128 (65%), Gaps = 6/128 (4%)
Query: 34 ESARKSEPPAPVRRQSYSSTSRGISVTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGC 93
+SA K EP +P YS ++ + + ++ + I C++CGDK+SG HYGV CEGC
Sbjct: 75 QSAIKVEPASP---PYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGC 131
Query: 94 KGFFRRSQQSNATYS-CPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQ 152
KGFFRR+ + Y C NC I + SRN+CQ+CR QKCLAVGMS +A++FGRM + +
Sbjct: 132 KGFFRRTIRLKLIYDRC--DLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAE 189
Query: 153 RDSLYAEV 160
++ L AE+
Sbjct: 190 KEKLLAEI 197
Score = 92.8 bits (229), Expect = 7e-19
Identities = 63/212 (29%), Positives = 107/212 (50%), Gaps = 9/212 (4%)
Query: 306 EEIENYQNKQREV---MWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLE 362
+ I Q + +EV ++Q C + EA+Q + E+AK I GF+ L NDQ+ LLK G E
Sbjct: 265 KHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHE 324
Query: 363 VVFIRMCRAFDSQNNTVYFDGKYASPDVFKSL--GCEDFISFVFEFGKSLCSMHLTEDEI 420
+++ + + + + + + KSL DF+ FEF ++ L + ++
Sbjct: 325 IIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDL 384
Query: 421 ALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDG-ILTKLICKVSTLRA 479
A+F A +++S DR L IE +Q + AL+ L+ NH E + KL+ K++ LR
Sbjct: 385 AIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQ 444
Query: 480 LCGRHTEKLMAFKAIYPDIVRLHFPPLYKELF 511
+ H + L K D + LH PL +E++
Sbjct: 445 IVTEHVQLLQVIKKTETD-MSLH--PLLQEIY 473
>gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo
sapiens]
Length = 423
Score = 119 bits (299), Expect = 5e-27
Identities = 66/155 (42%), Positives = 88/155 (56%), Gaps = 16/155 (10%)
Query: 5 PAAPDPAA--SEPGSSGA-----DAAAGSRETPLNQESARKSEPPAPVRRQSYSSTSRGI 57
P P+PAA + G GA A +G+ TP +P AP + +G
Sbjct: 20 PGGPNPAAQAARGGGGGAGEQQQQAGSGAPHTPQTP-----GQPGAPATPGTAGDKGQGP 74
Query: 58 SVTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLI 117
+ ++ + I C +CGDKSSG HYG TCEGCK FF+RS + N TY+C +NC I
Sbjct: 75 PGSGQSQ----QHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPI 130
Query: 118 DRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQ 152
D+ RN+CQ+CRL+KCL VGM R+AV+ GRM Q
Sbjct: 131 DQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQ 165
Score = 46.2 bits (108), Expect = 7e-05
Identities = 42/164 (25%), Positives = 74/164 (45%), Gaps = 4/164 (2%)
Query: 335 VEFAKRIDGFMELCQNDQIVLLKA--GSLEVVFIRMCRAFDSQNNTVYFDGKYASP-DVF 391
VE+A+ I F +L DQ+ LL+ L V+ C + G +ASP
Sbjct: 231 VEWARNIPFFPDLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSAD 290
Query: 392 KSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQL 451
+ + D I E + L ++H+ E + A VL ++D L + IE LQ+K Q
Sbjct: 291 RVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQC 350
Query: 452 ALQHVLQKNH-REDGILTKLICKVSTLRALCGRHTEKLMAFKAI 494
AL+ ++ + + KL+ ++ +LR + E+L + +
Sbjct: 351 ALEEYVRSQYPNQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLV 394
>gi|14149746 nuclear receptor subfamily 2, group F, member 2 isoform
a [Homo sapiens]
Length = 414
Score = 119 bits (297), Expect = 9e-27
Identities = 64/153 (41%), Positives = 83/153 (54%), Gaps = 13/153 (8%)
Query: 9 DPAASEPGSSGADAAA---------GSRETPLNQESARKSEPPAPVRRQSYSSTSRGISV 59
DP PGS G+ A+ G+ TP + PA Q+ + G
Sbjct: 10 DPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPA----QTAAGGQGGPGG 65
Query: 60 TKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDR 119
Q + I C +CGDKSSG HYG TCEGCK FF+RS + N +Y+C +NC ID+
Sbjct: 66 PGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQ 125
Query: 120 TSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQ 152
RN+CQ+CRL+KCL VGM R+AV+ GRM Q
Sbjct: 126 HHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQ 158
Score = 45.4 bits (106), Expect = 1e-04
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 4/164 (2%)
Query: 335 VEFAKRIDGFMELCQNDQIVLLKA--GSLEVVFIRMCRAFDSQNNTVYFDGKYASP-DVF 391
VE+A+ I F +L DQ+ LL+ L V+ C + G +ASP
Sbjct: 224 VEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSAD 283
Query: 392 KSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQL 451
+ + D I E + L ++H+ E + A VL ++D L + +E LQ+K Q
Sbjct: 284 RVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQC 343
Query: 452 ALQHVLQKNH-REDGILTKLICKVSTLRALCGRHTEKLMAFKAI 494
AL+ ++ + + KL+ ++ +LR + E+L + +
Sbjct: 344 ALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLV 387
>gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
Length = 463
Score = 119 bits (297), Expect = 9e-27
Identities = 66/161 (40%), Positives = 89/161 (55%), Gaps = 14/161 (8%)
Query: 3 SAPAAPDPAASEPGSSGADAAAGSRETPLNQESARKSEPPAP----VRRQSYSSTSRGIS 58
SA P A + P A S+ +N S+ + P P + +Y STS G S
Sbjct: 75 SAMGPPSGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPGIGNMNYPSTSPG-S 133
Query: 59 VTKKTHTSQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLID 118
+ K C ICGD+SSG HYGV +CEGCKGFF+R+ + + Y+C K+CLID
Sbjct: 134 LVKHI---------CAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLID 184
Query: 119 RTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAE 159
+ RNRCQ+CR QKCL +GM R+AV+ R ++R AE
Sbjct: 185 KRQRNRCQYCRYQKCLVMGMKREAVQEERQRSRERAESEAE 225
Score = 60.8 bits (146), Expect = 3e-09
Identities = 48/188 (25%), Positives = 84/188 (44%), Gaps = 4/188 (2%)
Query: 310 NYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMC 369
N +N + + +C + +VE+AKRI F +L DQ++LL+AG E++
Sbjct: 257 NMENSTNDPVTNICHAADKQLFT-LVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFS 315
Query: 370 -RAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVF-EFGKSLCSMHLTEDEIALFSAFV 427
R+ Q+ + G + S G V E + M + + E+ A V
Sbjct: 316 HRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIV 375
Query: 428 LMSADRSWLQEKVKIEKLQQKIQLALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTE 486
L + D L ++E L++K+ L+ + QK + G KL+ ++ LR++ + E
Sbjct: 376 LFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLE 435
Query: 487 KLMAFKAI 494
L FK I
Sbjct: 436 HLFFFKLI 443
>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
Length = 462
Score = 115 bits (289), Expect = 7e-26
Identities = 58/127 (45%), Positives = 79/127 (62%), Gaps = 16/127 (12%)
Query: 73 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 132
C ICGD+SSG HYGV +CEGCKGFF+R+ + + TY+C K+CLID+ RNRCQ+CR QK
Sbjct: 135 CAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQK 194
Query: 133 CLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGE--------AEPLTP 184
CLA+GM R+AV+ R K R+ ++ ++ ++ P E EP T
Sbjct: 195 CLAMGMKREAVQEERQRGKDRN-------ENEVESTSSANEDMPVERILEAELAVEPKTE 247
Query: 185 TYNISAN 191
TY + AN
Sbjct: 248 TY-VEAN 253
Score = 57.0 bits (136), Expect = 4e-08
Identities = 44/164 (26%), Positives = 78/164 (47%), Gaps = 3/164 (1%)
Query: 334 VVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMC-RAFDSQNNTVYFDGKYASPDVFK 392
+VE+AKRI F EL +DQ++LL+AG E++ R+ ++ + G + +
Sbjct: 279 LVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAH 338
Query: 393 SLGCEDFISFVF-EFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQL 451
S G V E + M + + E+ A VL + D L ++E L++K+
Sbjct: 339 SAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYA 398
Query: 452 ALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAI 494
+L+ + K + G KL+ ++ LR++ + E L FK I
Sbjct: 399 SLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLI 442
>gi|189491766 nuclear receptor subfamily 2, group C, member 1
isoform c [Homo sapiens]
Length = 483
Score = 114 bits (286), Expect = 2e-25
Identities = 62/152 (40%), Positives = 94/152 (61%), Gaps = 15/152 (9%)
Query: 73 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 132
C +CGDK+SG HYG +TCEGCKGFF+RS + N YSC K+C+I++ RNRCQ+CRLQ+
Sbjct: 113 CVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQR 172
Query: 133 CLAVGMSRDAVKFGR----MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEP--LTPTY 186
C+A GM +D+V+ R +S+++ + A +K +++ R P A P +T +
Sbjct: 173 CIAFGMKQDSVQCERKPIEVSREKSSNCAASTEKIYIRKDLR----SPLTATPTFVTDSE 228
Query: 187 NISANGLTELHDDLSNYIDGHTPEGSKADSAV 218
+ + GL D +++ H P G K +SAV
Sbjct: 229 STRSTGLL----DSGMFMNIH-PSGVKTESAV 255
>gi|73808084 nuclear receptor subfamily 2, group C, member 1 isoform
b [Homo sapiens]
Length = 467
Score = 114 bits (286), Expect = 2e-25
Identities = 62/152 (40%), Positives = 94/152 (61%), Gaps = 15/152 (9%)
Query: 73 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 132
C +CGDK+SG HYG +TCEGCKGFF+RS + N YSC K+C+I++ RNRCQ+CRLQ+
Sbjct: 113 CVVCGDKASGRHYGAVTCEGCKGFFKRSIRKNLVYSCRGSKDCIINKHHRNRCQYCRLQR 172
Query: 133 CLAVGMSRDAVKFGR----MSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEP--LTPTY 186
C+A GM +D+V+ R +S+++ + A +K +++ R P A P +T +
Sbjct: 173 CIAFGMKQDSVQCERKPIEVSREKSSNCAASTEKIYIRKDLR----SPLTATPTFVTDSE 228
Query: 187 NISANGLTELHDDLSNYIDGHTPEGSKADSAV 218
+ + GL D +++ H P G K +SAV
Sbjct: 229 STRSTGLL----DSGMFMNIH-PSGVKTESAV 255
>gi|11415052 retinoid X receptor, beta [Homo sapiens]
Length = 533
Score = 113 bits (283), Expect = 4e-25
Identities = 48/82 (58%), Positives = 61/82 (74%)
Query: 73 CKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQK 132
C ICGD+SSG HYGV +CEGCKGFF+R+ + + TYSC K+C +D+ RNRCQ+CR QK
Sbjct: 205 CAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQK 264
Query: 133 CLAVGMSRDAVKFGRMSKKQRD 154
CLA GM R+AV+ R K +D
Sbjct: 265 CLATGMKREAVQEERQRGKDKD 286
Score = 58.9 bits (141), Expect = 1e-08
Identities = 44/164 (26%), Positives = 79/164 (48%), Gaps = 3/164 (1%)
Query: 334 VVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMC-RAFDSQNNTVYFDGKYASPDVFK 392
+VE+AKRI F L +DQ++LL+AG E++ R+ D ++ + G + +
Sbjct: 350 LVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAH 409
Query: 393 SLGCEDFISFVF-EFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQL 451
S G V E + M + + E+ A +L + D L ++E L++K+
Sbjct: 410 SAGVGAIFDRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYA 469
Query: 452 ALQ-HVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAI 494
+L+ + QK + G KL+ ++ LR++ + E L FK I
Sbjct: 470 SLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLI 513
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,997,558
Number of Sequences: 37866
Number of extensions: 986052
Number of successful extensions: 6374
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 142
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 5866
Number of HSP's gapped (non-prelim): 421
length of query: 523
length of database: 18,247,518
effective HSP length: 107
effective length of query: 416
effective length of database: 14,195,856
effective search space: 5905476096
effective search space used: 5905476096
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.