Search of human proteins with 197276625

Search of human proteins with 197276625

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|197276625 solute carrier family 6 (neurotransmitter
transporter, taurine), member 6 isoform b [Homo sapiens]
         (200 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|197276625 solute carrier family 6 (neurotransmitter transport...   429   e-121
gi|197276623 solute carrier family 6 (neurotransmitter transport...   429   e-121
gi|54607094 solute carrier family 6 (neurotransmitter transporte...   429   e-121
gi|171184408 solute carrier family 6 (neurotransmitter transport...   236   1e-62
gi|171184406 solute carrier family 6 (neurotransmitter transport...   236   1e-62
gi|171184404 solute carrier family 6 (neurotransmitter transport...   236   1e-62
gi|7657587 solute carrier family 6 (neurotransmitter transporter...   234   4e-62
gi|21361581 solute carrier family 6 (neurotransmitter transporte...   232   1e-61
gi|5032097 solute carrier family 6 member 8 isoform 1 [Homo sapi...   196   8e-51
gi|218563756 solute carrier family 6 member 8 isoform 2 [Homo sa...   196   8e-51
gi|188528618 solute carrier family 6 (neurotransmitter transport...   188   3e-48
gi|4557046 solute carrier family 6 member 2 [Homo sapiens]            186   1e-47
gi|4507043 solute carrier family 6 member 4 [Homo sapiens]            179   1e-45
gi|4507041 solute carrier family 6 (neurotransmitter transporter...   179   1e-45
gi|134304856 solute carrier family 6, member 7 [Homo sapiens]         168   3e-42
gi|92859670 solute carrier family 6 (neurotransmitter transporte...   167   5e-42
gi|67782313 solute carrier family 6 member 9 isoform 1 [Homo sap...   162   2e-40
gi|67782317 solute carrier family 6 member 9 isoform 3 [Homo sap...   159   1e-39
gi|67782315 solute carrier family 6 member 9 isoform 2 [Homo sap...   159   1e-39
gi|6005715 solute carrier family 6 (amino acid transporter), mem...   154   4e-38
gi|58219014 solute carrier family 6, member 17 [Homo sapiens]         152   1e-37
gi|21361693 solute carrier family 6, member 15 isoform 2 [Homo s...   148   3e-36
gi|33354281 solute carrier family 6, member 15 isoform 1 [Homo s...   148   3e-36
gi|11181770 solute carrier family 6, member 20 isoform 1 [Homo s...   140   9e-34
gi|12408638 solute carrier family 6, member 20 isoform 2 [Homo s...   140   9e-34
gi|194018524 solute carrier family 6, member 18 [Homo sapiens]        138   4e-33
gi|51468073 solute carrier family 6, member 19 [Homo sapiens]         136   1e-32
gi|55749589 solute carrier family 6, member 16 [Homo sapiens]         105   3e-23
gi|218563758 solute carrier family 6 member 8 isoform 3 [Homo sa...   100   6e-22
gi|226437581 solute carrier family 6, member 15 isoform 3 [Homo ...    80   9e-16

>gi|197276625 solute carrier family 6 (neurotransmitter transporter,
           taurine), member 6 isoform b [Homo sapiens]
          Length = 200

 Score =  429 bits (1104), Expect = e-121
 Identities = 200/200 (100%), Positives = 200/200 (100%)

Query: 1   MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVG 60
           MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVG
Sbjct: 1   MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVG 60

Query: 61  LGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLF 120
           LGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLF
Sbjct: 61  LGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLF 120

Query: 121 SGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNK 180
           SGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNK
Sbjct: 121 SGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNK 180

Query: 181 SVWITISSTNFTSPVIEFWE 200
           SVWITISSTNFTSPVIEFWE
Sbjct: 181 SVWITISSTNFTSPVIEFWE 200


>gi|197276623 solute carrier family 6 (neurotransmitter transporter,
           taurine), member 6 isoform a [Homo sapiens]
          Length = 620

 Score =  429 bits (1104), Expect = e-121
 Identities = 200/200 (100%), Positives = 200/200 (100%)

Query: 1   MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVG 60
           MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVG
Sbjct: 1   MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVG 60

Query: 61  LGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLF 120
           LGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLF
Sbjct: 61  LGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLF 120

Query: 121 SGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNK 180
           SGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNK
Sbjct: 121 SGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNK 180

Query: 181 SVWITISSTNFTSPVIEFWE 200
           SVWITISSTNFTSPVIEFWE
Sbjct: 181 SVWITISSTNFTSPVIEFWE 200


>gi|54607094 solute carrier family 6 (neurotransmitter transporter,
           taurine), member 6 isoform a [Homo sapiens]
          Length = 620

 Score =  429 bits (1104), Expect = e-121
 Identities = 200/200 (100%), Positives = 200/200 (100%)

Query: 1   MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVG 60
           MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVG
Sbjct: 1   MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVG 60

Query: 61  LGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLF 120
           LGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLF
Sbjct: 61  LGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLF 120

Query: 121 SGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNK 180
           SGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNK
Sbjct: 121 SGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNK 180

Query: 181 SVWITISSTNFTSPVIEFWE 200
           SVWITISSTNFTSPVIEFWE
Sbjct: 181 SVWITISSTNFTSPVIEFWE 200


>gi|171184408 solute carrier family 6 (neurotransmitter transporter,
           betaine/GABA), member 12 [Homo sapiens]
          Length = 614

 Score =  236 bits (601), Expect = 1e-62
 Identities = 107/174 (61%), Positives = 127/174 (72%), Gaps = 2/174 (1%)

Query: 27  GTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIF 86
           G + + E E +   R +W++K++FVLSVAG  +GLGNVWRFPYLCYKNGGGAF IPYFIF
Sbjct: 22  GEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIF 81

Query: 87  LFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWAT 146
            F  G+PVFFLE+ +GQYTS+G +T W KICPLF GIG ASVVI S LNVYYI+ILAWA 
Sbjct: 82  FFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWAL 141

Query: 147 YYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWE 200
           +YLF SF  ELPW  CN+ WNT HC +     +          NFTSPV+EFWE
Sbjct: 142 FYLFSSFTSELPWTTCNNFWNTEHCTD--FLNHSGAGTVTPFENFTSPVMEFWE 193


>gi|171184406 solute carrier family 6 (neurotransmitter transporter,
           betaine/GABA), member 12 [Homo sapiens]
          Length = 614

 Score =  236 bits (601), Expect = 1e-62
 Identities = 107/174 (61%), Positives = 127/174 (72%), Gaps = 2/174 (1%)

Query: 27  GTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIF 86
           G + + E E +   R +W++K++FVLSVAG  +GLGNVWRFPYLCYKNGGGAF IPYFIF
Sbjct: 22  GEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIF 81

Query: 87  LFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWAT 146
            F  G+PVFFLE+ +GQYTS+G +T W KICPLF GIG ASVVI S LNVYYI+ILAWA 
Sbjct: 82  FFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWAL 141

Query: 147 YYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWE 200
           +YLF SF  ELPW  CN+ WNT HC +     +          NFTSPV+EFWE
Sbjct: 142 FYLFSSFTSELPWTTCNNFWNTEHCTD--FLNHSGAGTVTPFENFTSPVMEFWE 193


>gi|171184404 solute carrier family 6 (neurotransmitter transporter,
           betaine/GABA), member 12 [Homo sapiens]
          Length = 614

 Score =  236 bits (601), Expect = 1e-62
 Identities = 107/174 (61%), Positives = 127/174 (72%), Gaps = 2/174 (1%)

Query: 27  GTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIF 86
           G + + E E +   R +W++K++FVLSVAG  +GLGNVWRFPYLCYKNGGGAF IPYFIF
Sbjct: 22  GEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIF 81

Query: 87  LFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWAT 146
            F  G+PVFFLE+ +GQYTS+G +T W KICPLF GIG ASVVI S LNVYYI+ILAWA 
Sbjct: 82  FFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWAL 141

Query: 147 YYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWE 200
           +YLF SF  ELPW  CN+ WNT HC +     +          NFTSPV+EFWE
Sbjct: 142 FYLFSSFTSELPWTTCNNFWNTEHCTD--FLNHSGAGTVTPFENFTSPVMEFWE 193


>gi|7657587 solute carrier family 6 (neurotransmitter transporter,
           GABA), member 11 [Homo sapiens]
          Length = 632

 Score =  234 bits (597), Expect = 4e-62
 Identities = 107/180 (59%), Positives = 131/180 (72%), Gaps = 1/180 (0%)

Query: 21  SPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFL 80
           S G +P   P  + +    +R  W++K++FVLSVAG  +GLGNVWRFPYLCYKNGGGAFL
Sbjct: 30  SGGAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFL 89

Query: 81  IPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIV 140
           IPY +F    G+PVFFLE  +GQ+TSEGGITCW K+CPLF GIGYA+ VI + LNVYYI+
Sbjct: 90  IPYVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYII 149

Query: 141 ILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWE 200
           ILAWA +YL   F  ELPWA C H WNT +C+E   + N S +  +S  N TSPV+EFWE
Sbjct: 150 ILAWAIFYLSNCFTTELPWATCGHEWNTENCVE-FQKLNVSNYSHVSLQNATSPVMEFWE 208


>gi|21361581 solute carrier family 6 (neurotransmitter transporter,
           GABA), member 13 [Homo sapiens]
          Length = 602

 Score =  232 bits (592), Expect = 1e-61
 Identities = 107/170 (62%), Positives = 128/170 (75%), Gaps = 3/170 (1%)

Query: 31  EDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGS 90
           E + E    +R  W++K++FVLSVAG  +GLGNVWRFPYLCYKNGGGAF IPY +FLF  
Sbjct: 22  EKKEEDGTLERGHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLVFLFTC 81

Query: 91  GLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLF 150
           G+PVF LE  +GQYTS+GG+T W KICP+F GIGYAS +IV LLNVYYI++LAWA +YLF
Sbjct: 82  GIPVFLLETALGQYTSQGGVTAWRKICPIFEGIGYASQMIVILLNVYYIIVLAWALFYLF 141

Query: 151 QSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWE 200
            SF  +LPW  C H WNT HCME   + N S  +  +S N TSPVIEFWE
Sbjct: 142 SSFTIDLPWGGCYHEWNTEHCME-FQKTNGS--LNGTSENATSPVIEFWE 188


>gi|5032097 solute carrier family 6 member 8 isoform 1 [Homo
           sapiens]
          Length = 635

 Score =  196 bits (499), Expect = 8e-51
 Identities = 97/198 (48%), Positives = 120/198 (60%), Gaps = 18/198 (9%)

Query: 17  ILKPSPGKSPGTRPEDEAEGKP------PQREKWSSKIDFVLSVAGGFVGLGNVWRFPYL 70
           ++ P P  +P         G P      P RE W+ ++DF++S  G  VGLGNVWRFPYL
Sbjct: 22  LIAPGPDGAPAKGDGPVGLGTPGGRLAVPPRETWTRQMDFIMSCVGFAVGLGNVWRFPYL 81

Query: 71  CYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVI 130
           CYKNGGG FLIPY +     G+P+FFLEI +GQ+   G I  W  ICPLF G+GYAS+VI
Sbjct: 82  CYKNGGGVFLIPYVLIALVGGIPIFFLEISLGQFMKAGSINVW-NICPLFKGLGYASMVI 140

Query: 131 VSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTN 190
           V   N YYI++LAW  YYL +SF   LPWA C H+WNTP C+E    ++ +     S  N
Sbjct: 141 VFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWNTPDCVEIFRHEDCA---NASLAN 197

Query: 191 FT--------SPVIEFWE 200
            T        SPVIEFWE
Sbjct: 198 LTCDQLADRRSPVIEFWE 215


>gi|218563756 solute carrier family 6 member 8 isoform 2 [Homo
           sapiens]
          Length = 625

 Score =  196 bits (499), Expect = 8e-51
 Identities = 97/198 (48%), Positives = 120/198 (60%), Gaps = 18/198 (9%)

Query: 17  ILKPSPGKSPGTRPEDEAEGKP------PQREKWSSKIDFVLSVAGGFVGLGNVWRFPYL 70
           ++ P P  +P         G P      P RE W+ ++DF++S  G  VGLGNVWRFPYL
Sbjct: 22  LIAPGPDGAPAKGDGPVGLGTPGGRLAVPPRETWTRQMDFIMSCVGFAVGLGNVWRFPYL 81

Query: 71  CYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVI 130
           CYKNGGG FLIPY +     G+P+FFLEI +GQ+   G I  W  ICPLF G+GYAS+VI
Sbjct: 82  CYKNGGGVFLIPYVLIALVGGIPIFFLEISLGQFMKAGSINVW-NICPLFKGLGYASMVI 140

Query: 131 VSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTN 190
           V   N YYI++LAW  YYL +SF   LPWA C H+WNTP C+E    ++ +     S  N
Sbjct: 141 VFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWNTPDCVEIFRHEDCA---NASLAN 197

Query: 191 FT--------SPVIEFWE 200
            T        SPVIEFWE
Sbjct: 198 LTCDQLADRRSPVIEFWE 215


>gi|188528618 solute carrier family 6 (neurotransmitter transporter,
           GABA), member 1 [Homo sapiens]
          Length = 599

 Score =  188 bits (477), Expect = 3e-48
 Identities = 84/162 (51%), Positives = 111/162 (68%), Gaps = 9/162 (5%)

Query: 39  PQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLE 98
           P R+ W  + DF++S  G  +GLGNVWRFPYLC KNGGGAFLIPYF+ L  +G+P+F LE
Sbjct: 42  PDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLE 101

Query: 99  IIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELP 158
             +GQYTS GG+  W K+ P+F G+G A+ V+   LN+YYIVI++WA YYL+ SF   LP
Sbjct: 102 CSLGQYTSIGGLGVW-KLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLP 160

Query: 159 WAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWE 200
           W  C++ WNT  C         S +  +++TN TS V+EFWE
Sbjct: 161 WKQCDNPWNTDRCF--------SNYSMVNTTNMTSAVVEFWE 194


>gi|4557046 solute carrier family 6 member 2 [Homo sapiens]
          Length = 617

 Score =  186 bits (471), Expect = 1e-47
 Identities = 90/169 (53%), Positives = 110/169 (65%), Gaps = 6/169 (3%)

Query: 35  EGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPV 94
           +G    RE W  KIDF+LSV G  V L NVWRFPYLCYKNGGGAFLIPY +FL  +G+P+
Sbjct: 50  DGDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPL 109

Query: 95  FFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQ 154
           F++E+ +GQY  EG  T W KICP F G+GYA ++I   +  YY VI+AW+ YYLF SF 
Sbjct: 110 FYMELALGQYNREGAATVW-KICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFT 168

Query: 155 KELPWAHCNHSWNTPHCMEDTMRKNKSV---WITISSTNFTSPVIEFWE 200
             LPW  C H+WN+P+C  D    N SV       S   FT P  EF+E
Sbjct: 169 LNLPWTDCGHTWNSPNC-TDPKLLNGSVLGNHTKYSKYKFT-PAAEFYE 215


>gi|4507043 solute carrier family 6 member 4 [Homo sapiens]
          Length = 630

 Score =  179 bits (455), Expect = 1e-45
 Identities = 87/187 (46%), Positives = 113/187 (60%), Gaps = 12/187 (6%)

Query: 20  PSPGKS-------PGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCY 72
           PSPG         P T     AE    +RE W  K+DF+LSV G  V LGNVWRFPY+CY
Sbjct: 51  PSPGAGDDTRHSIPATTTTLVAELHQGERETWGKKVDFLLSVIGYAVDLGNVWRFPYICY 110

Query: 73  KNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVS 132
           +NGGGAFL+PY I     G+P+F++E+ +GQY   G I+ W KICP+F GIGYA  +I  
Sbjct: 111 QNGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAF 170

Query: 133 LLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFT 192
            +  YY  I+AWA YYL  SF  +LPW  C +SWNT +C  +   ++   W    + + T
Sbjct: 171 YIASYYNTIMAWALYYLISSFTDQLPWTSCKNSWNTGNC-TNYFSEDNITW----TLHST 225

Query: 193 SPVIEFW 199
           SP  EF+
Sbjct: 226 SPAEEFY 232


>gi|4507041 solute carrier family 6 (neurotransmitter transporter,
           dopamine), member 3 [Homo sapiens]
          Length = 620

 Score =  179 bits (455), Expect = 1e-45
 Identities = 78/160 (48%), Positives = 109/160 (68%), Gaps = 1/160 (0%)

Query: 41  REKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEII 100
           RE W  KIDF+LSV G  V L NVWRFPYLCYKNGGGAFL+PY +F+  +G+P+F++E+ 
Sbjct: 60  RETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELA 119

Query: 101 IGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA 160
           +GQ+  EG    W KICP+  G+G+  ++I   +  +Y VI+AWA +YLF SF  ELPW 
Sbjct: 120 LGQFNREGAAGVW-KICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWI 178

Query: 161 HCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWE 200
           HCN+SWN+P+C +     +      ++ T  T+P  E++E
Sbjct: 179 HCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFE 218


>gi|134304856 solute carrier family 6, member 7 [Homo sapiens]
          Length = 636

 Score =  168 bits (425), Expect = 3e-42
 Identities = 77/159 (48%), Positives = 107/159 (67%), Gaps = 1/159 (0%)

Query: 41  REKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEII 100
           R  W+ K+DF+LS  G  VGLGNVWRFPY  Y NGGGAFL+PYF+ L   G+P+FFLE+ 
Sbjct: 37  RGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELS 96

Query: 101 IGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA 160
           +GQ++S G +  W KI PLF G G A ++IV L+ +YY +I+A+  +YLF S   +LPW 
Sbjct: 97  LGQFSSLGPLAVW-KISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLPWE 155

Query: 161 HCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFW 199
           HC + WNT  C+E  + K+ +  + ++ T   SP  E+W
Sbjct: 156 HCGNWWNTELCLEHRVSKDGNGALPLNLTCTVSPSEEYW 194


>gi|92859670 solute carrier family 6 (neurotransmitter transporter,
           glycine), member 5 [Homo sapiens]
          Length = 797

 Score =  167 bits (423), Expect = 5e-42
 Identities = 75/145 (51%), Positives = 100/145 (68%), Gaps = 1/145 (0%)

Query: 31  EDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGS 90
           EDE   +   R  WSSK+DF+LS+ G  VGLGNVWRFPYL ++NGGGAFLIPY + L  +
Sbjct: 181 EDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALA 240

Query: 91  GLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLF 150
           GLP+FFLE+ +GQ+ S+G ++ W+ I P   G G A ++I  L+ +YY VI+ +  +YLF
Sbjct: 241 GLPIFFLEVSLGQFASQGPVSVWKAI-PALQGCGIAMLIISVLIAIYYNVIICYTLFYLF 299

Query: 151 QSFQKELPWAHCNHSWNTPHCMEDT 175
            SF   LPW  CN+ WNTP C + T
Sbjct: 300 ASFVSVLPWGSCNNPWNTPECKDKT 324


>gi|67782313 solute carrier family 6 member 9 isoform 1 [Homo
           sapiens]
          Length = 652

 Score =  162 bits (410), Expect = 2e-40
 Identities = 71/158 (44%), Positives = 101/158 (63%), Gaps = 1/158 (0%)

Query: 14  HKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYK 73
           H  +   SP ++     E     +  +R  W ++I+FVL+  G  VGLGNVWRFPYLCY+
Sbjct: 19  HGPVAPSSPEQNGAVPSEATKRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYR 78

Query: 74  NGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSL 133
           NGGGAF+ PYFI L   G+P+FF+E+  GQ+ S+G +  W +I P+F G+GY  +V+ + 
Sbjct: 79  NGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVW-RISPMFKGVGYGMMVVSTY 137

Query: 134 LNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHC 171
           + +YY V++  A YY F S    LPWA+CN+ WNT  C
Sbjct: 138 IGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTHDC 175


>gi|67782317 solute carrier family 6 member 9 isoform 3 [Homo
           sapiens]
          Length = 633

 Score =  159 bits (403), Expect = 1e-39
 Identities = 67/132 (50%), Positives = 93/132 (70%), Gaps = 1/132 (0%)

Query: 40  QREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEI 99
           +R  W ++I+FVL+  G  VGLGNVWRFPYLCY+NGGGAF+ PYFI L   G+P+FF+E+
Sbjct: 26  KRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMEL 85

Query: 100 IIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPW 159
             GQ+ S+G +  W +I P+F G+GY  +V+ + + +YY V++  A YY F S    LPW
Sbjct: 86  SFGQFASQGCLGVW-RISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPW 144

Query: 160 AHCNHSWNTPHC 171
           A+CN+ WNT  C
Sbjct: 145 AYCNNPWNTHDC 156


>gi|67782315 solute carrier family 6 member 9 isoform 2 [Homo
           sapiens]
          Length = 706

 Score =  159 bits (403), Expect = 1e-39
 Identities = 67/132 (50%), Positives = 93/132 (70%), Gaps = 1/132 (0%)

Query: 40  QREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEI 99
           +R  W ++I+FVL+  G  VGLGNVWRFPYLCY+NGGGAF+ PYFI L   G+P+FF+E+
Sbjct: 99  KRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMEL 158

Query: 100 IIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPW 159
             GQ+ S+G +  W +I P+F G+GY  +V+ + + +YY V++  A YY F S    LPW
Sbjct: 159 SFGQFASQGCLGVW-RISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPW 217

Query: 160 AHCNHSWNTPHC 171
           A+CN+ WNT  C
Sbjct: 218 AYCNNPWNTHDC 229


>gi|6005715 solute carrier family 6 (amino acid transporter), member
           14 [Homo sapiens]
          Length = 642

 Score =  154 bits (390), Expect = 4e-38
 Identities = 80/169 (47%), Positives = 109/169 (64%), Gaps = 22/169 (13%)

Query: 41  REKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEII 100
           R  WS K D++LS+ G  VGLGNVWRFPYL Y NGGGAFLIPY I L  +GLP+FFLE  
Sbjct: 36  RGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLECS 95

Query: 101 IGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA 160
           +GQ+ S G ++ W +I PLF G+G   V+I   + +YY VI+A++ YY+F SFQ ELPW 
Sbjct: 96  LGQFASLGPVSVW-RILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSELPWK 154

Query: 161 HCNHSWNTPHC-----------------MEDTMRKNKSVWITISSTNFT 192
           +C+ SW+  +C                 +++ ++ NKS W+ I+  NFT
Sbjct: 155 NCS-SWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKS-WVDIN--NFT 199


>gi|58219014 solute carrier family 6, member 17 [Homo sapiens]
          Length = 727

 Score =  152 bits (385), Expect = 1e-37
 Identities = 66/151 (43%), Positives = 97/151 (64%), Gaps = 1/151 (0%)

Query: 12  DFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLC 71
           D+ + +L  + G++ G +   E E     R  W+SK+ ++L+  G  VGLGN+WRFPYLC
Sbjct: 32  DYKQSVLNVA-GEAGGKQKAVEEELDAEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLC 90

Query: 72  YKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIV 131
            KNGGGA+L+PY + L   G+P+FFLE+ +GQ    G I  W  ICP   GIG++S ++ 
Sbjct: 91  QKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWHYICPRLGGIGFSSCIVC 150

Query: 132 SLLNVYYIVILAWATYYLFQSFQKELPWAHC 162
             + +YY VI+ W+ +Y F+SFQ  LPW+ C
Sbjct: 151 LFVGLYYNVIIGWSIFYFFKSFQYPLPWSEC 181


>gi|21361693 solute carrier family 6, member 15 isoform 2 [Homo
           sapiens]
          Length = 289

 Score =  148 bits (373), Expect = 3e-36
 Identities = 67/150 (44%), Positives = 93/150 (62%), Gaps = 6/150 (4%)

Query: 32  DEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSG 91
           +E      +R  W+SK+ ++L+  G  VGLGNVWRFPYLC KNGGGA+L+PY I L   G
Sbjct: 52  EEGSEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIG 111

Query: 92  LPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQ 151
           +P+FFLE+ +GQ    G I  W  I P   GIG+AS V+   + +YY VI+ W+ +Y  Q
Sbjct: 112 IPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQ 171

Query: 152 SFQKELPWAHC------NHSWNTPHCMEDT 175
           SFQ+ LPW  C      +H++  P C + +
Sbjct: 172 SFQQPLPWDQCPLVKNASHTFVEPECEQSS 201


>gi|33354281 solute carrier family 6, member 15 isoform 1 [Homo
           sapiens]
          Length = 730

 Score =  148 bits (373), Expect = 3e-36
 Identities = 67/150 (44%), Positives = 93/150 (62%), Gaps = 6/150 (4%)

Query: 32  DEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSG 91
           +E      +R  W+SK+ ++L+  G  VGLGNVWRFPYLC KNGGGA+L+PY I L   G
Sbjct: 52  EEGSEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIG 111

Query: 92  LPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQ 151
           +P+FFLE+ +GQ    G I  W  I P   GIG+AS V+   + +YY VI+ W+ +Y  Q
Sbjct: 112 IPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQ 171

Query: 152 SFQKELPWAHC------NHSWNTPHCMEDT 175
           SFQ+ LPW  C      +H++  P C + +
Sbjct: 172 SFQQPLPWDQCPLVKNASHTFVEPECEQSS 201


>gi|11181770 solute carrier family 6, member 20 isoform 1 [Homo
           sapiens]
          Length = 592

 Score =  140 bits (352), Expect = 9e-34
 Identities = 67/157 (42%), Positives = 93/157 (59%)

Query: 41  REKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEII 100
           R  W++ + FV +     VGLGNVWRFPYLC   GGG+FL+PY I L   G+P+ +LE+ 
Sbjct: 5   RPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELA 64

Query: 101 IGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA 160
           +GQ   +G I  W  I P  SG+G ASVV+   L++YY VI AWA +YLF SFQ  LPW+
Sbjct: 65  VGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWS 124

Query: 161 HCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIE 197
            C  + N     E+  + + + +     T   SP ++
Sbjct: 125 VCPLNGNHTGYDEECEKASSTQYFWYRKTLNISPSLQ 161


>gi|12408638 solute carrier family 6, member 20 isoform 2 [Homo
           sapiens]
          Length = 555

 Score =  140 bits (352), Expect = 9e-34
 Identities = 67/157 (42%), Positives = 93/157 (59%)

Query: 41  REKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEII 100
           R  W++ + FV +     VGLGNVWRFPYLC   GGG+FL+PY I L   G+P+ +LE+ 
Sbjct: 5   RPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELA 64

Query: 101 IGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA 160
           +GQ   +G I  W  I P  SG+G ASVV+   L++YY VI AWA +YLF SFQ  LPW+
Sbjct: 65  VGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWS 124

Query: 161 HCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIE 197
            C  + N     E+  + + + +     T   SP ++
Sbjct: 125 VCPLNGNHTGYDEECEKASSTQYFWYRKTLNISPSLQ 161


>gi|194018524 solute carrier family 6, member 18 [Homo sapiens]
          Length = 628

 Score =  138 bits (347), Expect = 4e-33
 Identities = 64/145 (44%), Positives = 86/145 (59%)

Query: 30  PEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFG 89
           P+  A     +R KW +K  ++LS  G  VGLGN+WRFPYLC   GGGAFLIPY I L  
Sbjct: 7   PDPAACDLGDERPKWDNKAQYLLSCTGFAVGLGNIWRFPYLCQTYGGGAFLIPYVIALVF 66

Query: 90  SGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYL 149
            G+P+F +E+ IGQ   +G +  W  I P  SG+G   V +  L+++YY  I+AW  +YL
Sbjct: 67  EGIPIFHVELAIGQRLRKGSVGVWTAISPYLSGVGLGCVTLSFLISLYYNTIVAWVLWYL 126

Query: 150 FQSFQKELPWAHCNHSWNTPHCMED 174
             SFQ  LPW+ C    N    +E+
Sbjct: 127 LNSFQHPLPWSSCPPDLNRTGFVEE 151


>gi|51468073 solute carrier family 6, member 19 [Homo sapiens]
          Length = 634

 Score =  136 bits (343), Expect = 1e-32
 Identities = 67/178 (37%), Positives = 103/178 (57%), Gaps = 10/178 (5%)

Query: 28  TRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFL 87
           T  ++EA  +P    KW +K  ++L+  G  VGLGNVWRFPYLC  +GGGAF+IP+ I L
Sbjct: 23  TIEQEEASSRP----KWDNKAQYMLTCLGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILL 78

Query: 88  FGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATY 147
              G+P+ +LE  IGQ    G +  W  I P   G+G AS++   ++ +YY  I++W  +
Sbjct: 79  VLEGIPLLYLEFAIGQRLRRGSLGVWSSIHPALKGLGLASMLTSFMVGLYYNTIISWIMW 138

Query: 148 YLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVW------ITISSTNFTSPVIEFW 199
           YLF SFQ+ LPW+ C  + N    +++  R +   +      + IS++   S  I++W
Sbjct: 139 YLFNSFQEPLPWSDCPLNENQTGYVDECARSSPVDYFWYRETLNISTSISDSGSIQWW 196


>gi|55749589 solute carrier family 6, member 16 [Homo sapiens]
          Length = 736

 Score =  105 bits (261), Expect = 3e-23
 Identities = 51/139 (36%), Positives = 77/139 (55%), Gaps = 4/139 (2%)

Query: 41  REKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEII 100
           R  WSSK +++L+  G  +    +WRF YL   +GG +F   Y   LF  G+P+ FLE+ 
Sbjct: 103 RPFWSSKTEYILAQVGFSMKPSCLWRFAYLWLNSGGCSFAAIYIFMLFLVGVPLLFLEMA 162

Query: 101 IGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA 160
            GQ   +GG+  W+ I P   G+GY+S ++  +L +Y+ V+ +W  +Y+ QSFQ  +PW 
Sbjct: 163 AGQSMRQGGMGVWKIIAPWIGGVGYSSFMVCFILGLYFNVVNSWIIFYMSQSFQFPVPWE 222

Query: 161 HC----NHSWNTPHCMEDT 175
            C    N S   P C   T
Sbjct: 223 KCPLTMNSSGFDPECERTT 241


>gi|218563758 solute carrier family 6 member 8 isoform 3 [Homo
           sapiens]
          Length = 520

 Score =  100 bits (250), Expect = 6e-22
 Identities = 51/101 (50%), Positives = 61/101 (60%), Gaps = 12/101 (11%)

Query: 108 GGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWN 167
           G I  W  ICPLF G+GYAS+VIV   N YYI++LAW  YYL +SF   LPWA C H+WN
Sbjct: 4   GSINVWN-ICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWN 62

Query: 168 TPHCMEDTMRKNKSVWITISSTNFT--------SPVIEFWE 200
           TP C+E    ++ +     S  N T        SPVIEFWE
Sbjct: 63  TPDCVEIFRHEDCA---NASLANLTCDQLADRRSPVIEFWE 100


>gi|226437581 solute carrier family 6, member 15 isoform 3 [Homo
           sapiens]
          Length = 623

 Score = 80.5 bits (197), Expect = 9e-16
 Identities = 36/91 (39%), Positives = 53/91 (58%), Gaps = 6/91 (6%)

Query: 91  GLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLF 150
           G+P+FFLE+ +GQ    G I  W  I P   GIG+AS V+   + +YY VI+ W+ +Y  
Sbjct: 4   GIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFS 63

Query: 151 QSFQKELPWAHC------NHSWNTPHCMEDT 175
           QSFQ+ LPW  C      +H++  P C + +
Sbjct: 64  QSFQQPLPWDQCPLVKNASHTFVEPECEQSS 94


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.141    0.474 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,135,087
Number of Sequences: 37866
Number of extensions: 432019
Number of successful extensions: 1327
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1273
Number of HSP's gapped (non-prelim): 45
length of query: 200
length of database: 18,247,518
effective HSP length: 97
effective length of query: 103
effective length of database: 14,574,516
effective search space: 1501175148
effective search space used: 1501175148
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.