Search of human proteins with 197276623

Search of human proteins with 197276623

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|197276623 solute carrier family 6 (neurotransmitter
transporter, taurine), member 6 isoform a [Homo sapiens]
         (620 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|197276623 solute carrier family 6 (neurotransmitter transport...  1293   0.0  
gi|54607094 solute carrier family 6 (neurotransmitter transporte...  1293   0.0  
gi|7657587 solute carrier family 6 (neurotransmitter transporter...   781   0.0  
gi|21361581 solute carrier family 6 (neurotransmitter transporte...   771   0.0  
gi|171184408 solute carrier family 6 (neurotransmitter transport...   763   0.0  
gi|171184406 solute carrier family 6 (neurotransmitter transport...   763   0.0  
gi|171184404 solute carrier family 6 (neurotransmitter transport...   763   0.0  
gi|5032097 solute carrier family 6 member 8 isoform 1 [Homo sapi...   686   0.0  
gi|218563756 solute carrier family 6 member 8 isoform 2 [Homo sa...   668   0.0  
gi|188528618 solute carrier family 6 (neurotransmitter transport...   616   e-176
gi|218563758 solute carrier family 6 member 8 isoform 3 [Homo sa...   590   e-168
gi|92859670 solute carrier family 6 (neurotransmitter transporte...   522   e-148
gi|4557046 solute carrier family 6 member 2 [Homo sapiens]            517   e-146
gi|4507041 solute carrier family 6 (neurotransmitter transporter...   501   e-142
gi|134304856 solute carrier family 6, member 7 [Homo sapiens]         498   e-141
gi|4507043 solute carrier family 6 member 4 [Homo sapiens]            482   e-136
gi|67782313 solute carrier family 6 member 9 isoform 1 [Homo sap...   471   e-133
gi|67782317 solute carrier family 6 member 9 isoform 3 [Homo sap...   469   e-132
gi|67782315 solute carrier family 6 member 9 isoform 2 [Homo sap...   469   e-132
gi|6005715 solute carrier family 6 (amino acid transporter), mem...   456   e-128
gi|197276625 solute carrier family 6 (neurotransmitter transport...   429   e-120
gi|51468073 solute carrier family 6, member 19 [Homo sapiens]         366   e-101
gi|194018524 solute carrier family 6, member 18 [Homo sapiens]        353   3e-97
gi|11181770 solute carrier family 6, member 20 isoform 1 [Homo s...   341   1e-93
gi|12408638 solute carrier family 6, member 20 isoform 2 [Homo s...   285   1e-76
gi|58219014 solute carrier family 6, member 17 [Homo sapiens]         275   1e-73
gi|33354281 solute carrier family 6, member 15 isoform 1 [Homo s...   256   4e-68
gi|226437581 solute carrier family 6, member 15 isoform 3 [Homo ...   188   1e-47
gi|21361693 solute carrier family 6, member 15 isoform 2 [Homo s...   183   4e-46
gi|55749589 solute carrier family 6, member 16 [Homo sapiens]         171   2e-42

>gi|197276623 solute carrier family 6 (neurotransmitter transporter,
           taurine), member 6 isoform a [Homo sapiens]
          Length = 620

 Score = 1293 bits (3345), Expect = 0.0
 Identities = 620/620 (100%), Positives = 620/620 (100%)

Query: 1   MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVG 60
           MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVG
Sbjct: 1   MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVG 60

Query: 61  LGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLF 120
           LGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLF
Sbjct: 61  LGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLF 120

Query: 121 SGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNK 180
           SGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNK
Sbjct: 121 SGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNK 180

Query: 181 SVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVR 240
           SVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVR
Sbjct: 181 SVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVR 240

Query: 241 STGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFF 300
           STGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFF
Sbjct: 241 STGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFF 300

Query: 301 SYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIA 360
           SYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIA
Sbjct: 301 SYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIA 360

Query: 361 DVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPS 420
           DVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPS
Sbjct: 361 DVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPS 420

Query: 421 FLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIA 480
           FLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIA
Sbjct: 421 FLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIA 480

Query: 481 WIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPN 540
           WIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPN
Sbjct: 481 WIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPN 540

Query: 541 WAIGLGWSLALSSMLCVPLVIVIRLCQTEGPFLVRVKYLLTPREPNRWAVEREGATPYNS 600
           WAIGLGWSLALSSMLCVPLVIVIRLCQTEGPFLVRVKYLLTPREPNRWAVEREGATPYNS
Sbjct: 541 WAIGLGWSLALSSMLCVPLVIVIRLCQTEGPFLVRVKYLLTPREPNRWAVEREGATPYNS 600

Query: 601 RTVMNGALVKPTHIIVETMM 620
           RTVMNGALVKPTHIIVETMM
Sbjct: 601 RTVMNGALVKPTHIIVETMM 620


>gi|54607094 solute carrier family 6 (neurotransmitter transporter,
           taurine), member 6 isoform a [Homo sapiens]
          Length = 620

 Score = 1293 bits (3345), Expect = 0.0
 Identities = 620/620 (100%), Positives = 620/620 (100%)

Query: 1   MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVG 60
           MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVG
Sbjct: 1   MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVG 60

Query: 61  LGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLF 120
           LGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLF
Sbjct: 61  LGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLF 120

Query: 121 SGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNK 180
           SGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNK
Sbjct: 121 SGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNK 180

Query: 181 SVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVR 240
           SVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVR
Sbjct: 181 SVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVR 240

Query: 241 STGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFF 300
           STGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFF
Sbjct: 241 STGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFF 300

Query: 301 SYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIA 360
           SYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIA
Sbjct: 301 SYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIA 360

Query: 361 DVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPS 420
           DVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPS
Sbjct: 361 DVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPS 420

Query: 421 FLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIA 480
           FLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIA
Sbjct: 421 FLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIA 480

Query: 481 WIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPN 540
           WIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPN
Sbjct: 481 WIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPN 540

Query: 541 WAIGLGWSLALSSMLCVPLVIVIRLCQTEGPFLVRVKYLLTPREPNRWAVEREGATPYNS 600
           WAIGLGWSLALSSMLCVPLVIVIRLCQTEGPFLVRVKYLLTPREPNRWAVEREGATPYNS
Sbjct: 541 WAIGLGWSLALSSMLCVPLVIVIRLCQTEGPFLVRVKYLLTPREPNRWAVEREGATPYNS 600

Query: 601 RTVMNGALVKPTHIIVETMM 620
           RTVMNGALVKPTHIIVETMM
Sbjct: 601 RTVMNGALVKPTHIIVETMM 620


>gi|7657587 solute carrier family 6 (neurotransmitter transporter,
           GABA), member 11 [Homo sapiens]
          Length = 632

 Score =  781 bits (2017), Expect = 0.0
 Identities = 360/562 (64%), Positives = 437/562 (77%), Gaps = 1/562 (0%)

Query: 21  SPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFL 80
           S G +P   P  + +    +R  W++K++FVLSVAG  +GLGNVWRFPYLCYKNGGGAFL
Sbjct: 30  SGGAAPARHPRVKRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFL 89

Query: 81  IPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIV 140
           IPY +F    G+PVFFLE  +GQ+TSEGGITCW K+CPLF GIGYA+ VI + LNVYYI+
Sbjct: 90  IPYVVFFICCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYII 149

Query: 141 ILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWE 200
           ILAWA +YL   F  ELPWA C H WNT +C+E   + N S +  +S  N TSPV+EFWE
Sbjct: 150 ILAWAIFYLSNCFTTELPWATCGHEWNTENCVE-FQKLNVSNYSHVSLQNATSPVMEFWE 208

Query: 201 RNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVL 260
             VL++S GI+H G+L+W+LALCLL  W +C+FCIWKG +STGKVVY TATFP+ MLL+L
Sbjct: 209 HRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLIL 268

Query: 261 LVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKY 320
           L+RG+TLPGA  GIKFYLYPD++RL DPQVW+DAGTQIFFSYAICLG +T+LGSYN Y  
Sbjct: 269 LIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNN 328

Query: 321 NSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTM 380
           N YRDC++L CLNSGTSFV+GFAIFS+LGFMA EQGV IA+VAESGPGLAFIAYPKAVTM
Sbjct: 329 NCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTM 388

Query: 381 MPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISY 440
           MPL   W+ LFF+ML+ LGLDSQFV VE  +T++VD+YP   R+GYRRE+ I  +  ISY
Sbjct: 389 MPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSVISY 448

Query: 441 LLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRP 500
            LGL M+TEGGMY+FQLFD YAASG+CLL+VA FEC  I W+YG +  YD IEDMIGYRP
Sbjct: 449 FLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDMIGYRP 508

Query: 501 GPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLV 560
              +K+ W ++TP +C G FIF L+KY PL YN  Y YP W  G+GW +ALSSMLC+PL 
Sbjct: 509 PSLIKWCWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGWLMALSSMLCIPLW 568

Query: 561 IVIRLCQTEGPFLVRVKYLLTP 582
           I I + +TEG    +++ L TP
Sbjct: 569 ICITVWKTEGTLPEKLQKLTTP 590


>gi|21361581 solute carrier family 6 (neurotransmitter transporter,
           GABA), member 13 [Homo sapiens]
          Length = 602

 Score =  771 bits (1992), Expect = 0.0
 Identities = 360/554 (64%), Positives = 434/554 (78%), Gaps = 3/554 (0%)

Query: 31  EDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGS 90
           E + E    +R  W++K++FVLSVAG  +GLGNVWRFPYLCYKNGGGAF IPY +FLF  
Sbjct: 22  EKKEEDGTLERGHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLVFLFTC 81

Query: 91  GLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLF 150
           G+PVF LE  +GQYTS+GG+T W KICP+F GIGYAS +IV LLNVYYI++LAWA +YLF
Sbjct: 82  GIPVFLLETALGQYTSQGGVTAWRKICPIFEGIGYASQMIVILLNVYYIIVLAWALFYLF 141

Query: 151 QSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSLSPGI 210
            SF  +LPW  C H WNT HCME   + N S  +  +S N TSPVIEFWER VL +S GI
Sbjct: 142 SSFTIDLPWGGCYHEWNTEHCME-FQKTNGS--LNGTSENATSPVIEFWERRVLKISDGI 198

Query: 211 DHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGA 270
            H G+L+W+LALCLLL W++C+FCIWKGV+STGKVVYFTATFP+ ML+VLL+RG+TLPGA
Sbjct: 199 QHLGALRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVVLLIRGVTLPGA 258

Query: 271 GAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLG 330
             GI+FYLYP++TRL DPQVW+DAGTQIFFS+AICLG +T+LGSYNKY  N YRDC+ L 
Sbjct: 259 AQGIQFYLYPNLTRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCYRDCIALC 318

Query: 331 CLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSIL 390
            LNSGTSFV+GFAIFSILGFM+QEQGV I++VAESGPGLAFIAYP+AV M+P    W+  
Sbjct: 319 FLNSGTSFVAGFAIFSILGFMSQEQGVPISEVAESGPGLAFIAYPRAVVMLPFSPLWACC 378

Query: 391 FFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEG 450
           FF M++LLGLDSQFV VE  +T+LVD+YP   RK  RRE+ I  V  +S+L+GL M+TEG
Sbjct: 379 FFFMVVLLGLDSQFVCVESLVTALVDMYPHVFRKKNRREVLILGVSVVSFLVGLIMLTEG 438

Query: 451 GMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAV 510
           GMYVFQLFDYYAASG+CLL+VA FE   +AW+YG    YD IEDMIGYRP P +KY W  
Sbjct: 439 GMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGAKRFYDNIEDMIGYRPWPLIKYCWLF 498

Query: 511 ITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRLCQTEG 570
           +TP +C   F+FSL+KY PLTYNK Y YP W   LGW LALSSM+C+P   + RL   +G
Sbjct: 499 LTPAVCTATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALSSMVCIPAWSLYRLGTLKG 558

Query: 571 PFLVRVKYLLTPRE 584
           PF  R++ L+ P E
Sbjct: 559 PFRERIRQLMCPAE 572


>gi|171184408 solute carrier family 6 (neurotransmitter transporter,
           betaine/GABA), member 12 [Homo sapiens]
          Length = 614

 Score =  763 bits (1971), Expect = 0.0
 Identities = 354/556 (63%), Positives = 432/556 (77%), Gaps = 2/556 (0%)

Query: 27  GTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIF 86
           G + + E E +   R +W++K++FVLSVAG  +GLGNVWRFPYLCYKNGGGAF IPYFIF
Sbjct: 22  GEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIF 81

Query: 87  LFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWAT 146
            F  G+PVFFLE+ +GQYTS+G +T W KICPLF GIG ASVVI S LNVYYI+ILAWA 
Sbjct: 82  FFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWAL 141

Query: 147 YYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSL 206
           +YLF SF  ELPW  CN+ WNT HC +     +          NFTSPV+EFWER VL +
Sbjct: 142 FYLFSSFTSELPWTTCNNFWNTEHCTD--FLNHSGAGTVTPFENFTSPVMEFWERRVLGI 199

Query: 207 SPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLT 266
           + GI   GSL+W+LALCLLL W++C+FCIWKGV+STGKVVYFTATFP+ ML++LL+RG+T
Sbjct: 200 TSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVT 259

Query: 267 LPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDC 326
           LPGA  GI +YL PD+ RL+DPQVW+DAGTQIFFS+AIC G +T+LGSYNKY  N Y+DC
Sbjct: 260 LPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDC 319

Query: 327 MLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTF 386
           + L  LNS TSFV+GF +FSILGFM+QEQGV I++VAESGPGLAFIA+PKAVTMMPL   
Sbjct: 320 IALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQL 379

Query: 387 WSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTM 446
           WS LFFIML+ LGLDSQFV VE  +T+ +D++P  LRK  RRE+ I  +  + YL+GL +
Sbjct: 380 WSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFL 439

Query: 447 VTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKY 506
           VTEGGMY+FQLFDYYA+SG+CLL+++ FE   I+W+YG D  YD IEDMIGYRP P +K 
Sbjct: 440 VTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKI 499

Query: 507 SWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRLC 566
           SW  +TP LC+  F+FSL KY PL YN  YVYP W   +GW LALSSM+CVPL +VI L 
Sbjct: 500 SWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLL 559

Query: 567 QTEGPFLVRVKYLLTP 582
           +T GPF  R++ L+TP
Sbjct: 560 KTRGPFRKRLRQLITP 575


>gi|171184406 solute carrier family 6 (neurotransmitter transporter,
           betaine/GABA), member 12 [Homo sapiens]
          Length = 614

 Score =  763 bits (1971), Expect = 0.0
 Identities = 354/556 (63%), Positives = 432/556 (77%), Gaps = 2/556 (0%)

Query: 27  GTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIF 86
           G + + E E +   R +W++K++FVLSVAG  +GLGNVWRFPYLCYKNGGGAF IPYFIF
Sbjct: 22  GEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIF 81

Query: 87  LFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWAT 146
            F  G+PVFFLE+ +GQYTS+G +T W KICPLF GIG ASVVI S LNVYYI+ILAWA 
Sbjct: 82  FFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWAL 141

Query: 147 YYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSL 206
           +YLF SF  ELPW  CN+ WNT HC +     +          NFTSPV+EFWER VL +
Sbjct: 142 FYLFSSFTSELPWTTCNNFWNTEHCTD--FLNHSGAGTVTPFENFTSPVMEFWERRVLGI 199

Query: 207 SPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLT 266
           + GI   GSL+W+LALCLLL W++C+FCIWKGV+STGKVVYFTATFP+ ML++LL+RG+T
Sbjct: 200 TSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVT 259

Query: 267 LPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDC 326
           LPGA  GI +YL PD+ RL+DPQVW+DAGTQIFFS+AIC G +T+LGSYNKY  N Y+DC
Sbjct: 260 LPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDC 319

Query: 327 MLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTF 386
           + L  LNS TSFV+GF +FSILGFM+QEQGV I++VAESGPGLAFIA+PKAVTMMPL   
Sbjct: 320 IALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQL 379

Query: 387 WSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTM 446
           WS LFFIML+ LGLDSQFV VE  +T+ +D++P  LRK  RRE+ I  +  + YL+GL +
Sbjct: 380 WSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFL 439

Query: 447 VTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKY 506
           VTEGGMY+FQLFDYYA+SG+CLL+++ FE   I+W+YG D  YD IEDMIGYRP P +K 
Sbjct: 440 VTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKI 499

Query: 507 SWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRLC 566
           SW  +TP LC+  F+FSL KY PL YN  YVYP W   +GW LALSSM+CVPL +VI L 
Sbjct: 500 SWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLL 559

Query: 567 QTEGPFLVRVKYLLTP 582
           +T GPF  R++ L+TP
Sbjct: 560 KTRGPFRKRLRQLITP 575


>gi|171184404 solute carrier family 6 (neurotransmitter transporter,
           betaine/GABA), member 12 [Homo sapiens]
          Length = 614

 Score =  763 bits (1971), Expect = 0.0
 Identities = 354/556 (63%), Positives = 432/556 (77%), Gaps = 2/556 (0%)

Query: 27  GTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIF 86
           G + + E E +   R +W++K++FVLSVAG  +GLGNVWRFPYLCYKNGGGAF IPYFIF
Sbjct: 22  GEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIF 81

Query: 87  LFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWAT 146
            F  G+PVFFLE+ +GQYTS+G +T W KICPLF GIG ASVVI S LNVYYI+ILAWA 
Sbjct: 82  FFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWAL 141

Query: 147 YYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSL 206
           +YLF SF  ELPW  CN+ WNT HC +     +          NFTSPV+EFWER VL +
Sbjct: 142 FYLFSSFTSELPWTTCNNFWNTEHCTD--FLNHSGAGTVTPFENFTSPVMEFWERRVLGI 199

Query: 207 SPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLT 266
           + GI   GSL+W+LALCLLL W++C+FCIWKGV+STGKVVYFTATFP+ ML++LL+RG+T
Sbjct: 200 TSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVT 259

Query: 267 LPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDC 326
           LPGA  GI +YL PD+ RL+DPQVW+DAGTQIFFS+AIC G +T+LGSYNKY  N Y+DC
Sbjct: 260 LPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDC 319

Query: 327 MLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTF 386
           + L  LNS TSFV+GF +FSILGFM+QEQGV I++VAESGPGLAFIA+PKAVTMMPL   
Sbjct: 320 IALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQL 379

Query: 387 WSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTM 446
           WS LFFIML+ LGLDSQFV VE  +T+ +D++P  LRK  RRE+ I  +  + YL+GL +
Sbjct: 380 WSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFL 439

Query: 447 VTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKY 506
           VTEGGMY+FQLFDYYA+SG+CLL+++ FE   I+W+YG D  YD IEDMIGYRP P +K 
Sbjct: 440 VTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKI 499

Query: 507 SWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRLC 566
           SW  +TP LC+  F+FSL KY PL YN  YVYP W   +GW LALSSM+CVPL +VI L 
Sbjct: 500 SWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLL 559

Query: 567 QTEGPFLVRVKYLLTP 582
           +T GPF  R++ L+TP
Sbjct: 560 KTRGPFRKRLRQLITP 575


>gi|5032097 solute carrier family 6 member 8 isoform 1 [Homo
           sapiens]
          Length = 635

 Score =  686 bits (1770), Expect = 0.0
 Identities = 328/580 (56%), Positives = 415/580 (71%), Gaps = 18/580 (3%)

Query: 17  ILKPSPGKSPGTRPEDEAEGKP------PQREKWSSKIDFVLSVAGGFVGLGNVWRFPYL 70
           ++ P P  +P         G P      P RE W+ ++DF++S  G  VGLGNVWRFPYL
Sbjct: 22  LIAPGPDGAPAKGDGPVGLGTPGGRLAVPPRETWTRQMDFIMSCVGFAVGLGNVWRFPYL 81

Query: 71  CYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVI 130
           CYKNGGG FLIPY +     G+P+FFLEI +GQ+   G I  W  ICPLF G+GYAS+VI
Sbjct: 82  CYKNGGGVFLIPYVLIALVGGIPIFFLEISLGQFMKAGSINVWN-ICPLFKGLGYASMVI 140

Query: 131 VSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTN 190
           V   N YYI++LAW  YYL +SF   LPWA C H+WNTP C+E    ++ +     S  N
Sbjct: 141 VFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWNTPDCVEIFRHEDCA---NASLAN 197

Query: 191 FT--------SPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRST 242
            T        SPVIEFWE  VL LS G++ PG+L W++ LCLL  W++ +FC+WKGV+ST
Sbjct: 198 LTCDQLADRRSPVIEFWENKVLRLSGGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKST 257

Query: 243 GKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSY 302
           GK+VYFTATFP+ +L+VLLVRG+ LPGA  GI +YL PD ++L  PQVWIDAGTQIFFSY
Sbjct: 258 GKIVYFTATFPYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSY 317

Query: 303 AICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADV 362
           AI LGA+T+LGSYN++  N Y+D ++L  +NSGTSF +GF +FSILGFMA EQGV I+ V
Sbjct: 318 AIGLGALTALGSYNRFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMAAEQGVHISKV 377

Query: 363 AESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFL 422
           AESGPGLAFIAYP+AVT+MP+   W+ LFF MLLLLGLDSQFV VEG IT L+DL P+  
Sbjct: 378 AESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASY 437

Query: 423 RKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWI 482
              ++REI +A  C++ +++ L+MVT+GGMYVFQLFDYY+ASG  LLW AF+EC V+AW+
Sbjct: 438 YFRFQREISVALCCALCFVIDLSMVTDGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWV 497

Query: 483 YGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWA 542
           YG D   D I  MIGYRP PWMK+ W+  TP++C+G FIF++V Y PL YN TYVYP W 
Sbjct: 498 YGADRFMDDIACMIGYRPCPWMKWCWSFFTPLVCMGIFIFNVVYYEPLVYNNTYVYPWWG 557

Query: 543 IGLGWSLALSSMLCVPLVIVIRLCQTEGPFLVRVKYLLTP 582
             +GW+ ALSSMLCVPL ++  L + +G    R ++L  P
Sbjct: 558 EAMGWAFALSSMLCVPLHLLGCLLRAKGTMAERWQHLTQP 597


>gi|218563756 solute carrier family 6 member 8 isoform 2 [Homo
           sapiens]
          Length = 625

 Score =  668 bits (1724), Expect = 0.0
 Identities = 324/580 (55%), Positives = 408/580 (70%), Gaps = 28/580 (4%)

Query: 17  ILKPSPGKSPGTRPEDEAEGKP------PQREKWSSKIDFVLSVAGGFVGLGNVWRFPYL 70
           ++ P P  +P         G P      P RE W+ ++DF++S  G  VGLGNVWRFPYL
Sbjct: 22  LIAPGPDGAPAKGDGPVGLGTPGGRLAVPPRETWTRQMDFIMSCVGFAVGLGNVWRFPYL 81

Query: 71  CYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVI 130
           CYKNGGG FLIPY +     G+P+FFLEI +GQ+   G I  W  ICPLF G+GYAS+VI
Sbjct: 82  CYKNGGGVFLIPYVLIALVGGIPIFFLEISLGQFMKAGSINVWN-ICPLFKGLGYASMVI 140

Query: 131 VSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTN 190
           V   N YYI++LAW  YYL +SF   LPWA C H+WNTP C+E    ++ +     S  N
Sbjct: 141 VFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWNTPDCVEIFRHEDCA---NASLAN 197

Query: 191 FT--------SPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRST 242
            T        SPVIEFWE  VL LS G++ PG+L W++ LCLL  W++ +FC+WKGV+ST
Sbjct: 198 LTCDQLADRRSPVIEFWENKVLRLSGGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKST 257

Query: 243 GKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSY 302
           GK+VYFTATFP+ +L+VLLVRG+ LPGA  GI +YL PD ++L  PQVWIDAGTQIFFSY
Sbjct: 258 GKIVYFTATFPYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSY 317

Query: 303 AICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADV 362
           AI LGA+T+LGSYN++  N Y          +GTSF +GF +FSILGFMA EQGV I+ V
Sbjct: 318 AIGLGALTALGSYNRFNNNCY----------NGTSFFAGFVVFSILGFMAAEQGVHISKV 367

Query: 363 AESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFL 422
           AESGPGLAFIAYP+AVT+MP+   W+ LFF MLLLLGLDSQFV VEG IT L+DL P+  
Sbjct: 368 AESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASY 427

Query: 423 RKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWI 482
              ++REI +A  C++ +++ L+MVT+GGMYVFQLFDYY+ASG  LLW AF+EC V+AW+
Sbjct: 428 YFRFQREISVALCCALCFVIDLSMVTDGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWV 487

Query: 483 YGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWA 542
           YG D   D I  MIGYRP PWMK+ W+  TP++C+G FIF++V Y PL YN TYVYP W 
Sbjct: 488 YGADRFMDDIACMIGYRPCPWMKWCWSFFTPLVCMGIFIFNVVYYEPLVYNNTYVYPWWG 547

Query: 543 IGLGWSLALSSMLCVPLVIVIRLCQTEGPFLVRVKYLLTP 582
             +GW+ ALSSMLCVPL ++  L + +G    R ++L  P
Sbjct: 548 EAMGWAFALSSMLCVPLHLLGCLLRAKGTMAERWQHLTQP 587


>gi|188528618 solute carrier family 6 (neurotransmitter transporter,
           GABA), member 1 [Homo sapiens]
          Length = 599

 Score =  616 bits (1589), Expect = e-176
 Identities = 286/546 (52%), Positives = 386/546 (70%), Gaps = 12/546 (2%)

Query: 39  PQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLE 98
           P R+ W  + DF++S  G  +GLGNVWRFPYLC KNGGGAFLIPYF+ L  +G+P+F LE
Sbjct: 42  PDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLE 101

Query: 99  IIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELP 158
             +GQYTS GG+  W K+ P+F G+G A+ V+   LN+YYIVI++WA YYL+ SF   LP
Sbjct: 102 CSLGQYTSIGGLGVW-KLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLP 160

Query: 159 WAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKW 218
           W  C++ WNT  C  +        +  +++TN TS V+EFWERN+  ++ G+D PG ++W
Sbjct: 161 WKQCDNPWNTDRCFSN--------YSMVNTTNMTSAVVEFWERNMHQMTDGLDKPGQIRW 212

Query: 219 DLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYL 278
            LA+ L + W++ +FCIWKGV  TGKVVYF+AT+P+ ML++L  RG+TLPGA  GI FY+
Sbjct: 213 PLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYI 272

Query: 279 YPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSF 338
            P+  +L D +VW+DA TQIFFSY + LG++ +LGSYN +  N YRD +++ C+NS TS 
Sbjct: 273 TPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSM 332

Query: 339 VSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLL 398
            +GF IFSI+GFMA      IADVA SGPGLAF+AYP+AVT +P+   W+ILFF MLL+L
Sbjct: 333 FAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLML 392

Query: 399 GLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLF 458
           G+DSQF  VEG IT+LVD YP  LR   RRE+FIA VC ISYL+GL+ +T+GG+YVF+LF
Sbjct: 393 GIDSQFCTVEGFITALVDEYPRLLRN--RRELFIAAVCIISYLIGLSNITQGGIYVFKLF 450

Query: 459 DYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVG 518
           DYY+ASG+ LL++ FFEC  I+W YG +  YD I++M+G RP  W K  W+  TP++  G
Sbjct: 451 DYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAG 510

Query: 519 CFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRLCQTEGPFLVRVKY 578
            FIFS V+  PLT    YV+P W  G+GW +ALSSM+ +P  +       +G    R++ 
Sbjct: 511 VFIFSAVQMTPLTMG-NYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRIQV 569

Query: 579 LLTPRE 584
           ++ P E
Sbjct: 570 MVQPSE 575


>gi|218563758 solute carrier family 6 member 8 isoform 3 [Homo
           sapiens]
          Length = 520

 Score =  590 bits (1521), Expect = e-168
 Identities = 282/483 (58%), Positives = 356/483 (73%), Gaps = 12/483 (2%)

Query: 108 GGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWN 167
           G I  W  ICPLF G+GYAS+VIV   N YYI++LAW  YYL +SF   LPWA C H+WN
Sbjct: 4   GSINVWN-ICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWN 62

Query: 168 TPHCMEDTMRKNKSVWITISSTNFT--------SPVIEFWERNVLSLSPGIDHPGSLKWD 219
           TP C+E    ++ +     S  N T        SPVIEFWE  VL LS G++ PG+L W+
Sbjct: 63  TPDCVEIFRHEDCA---NASLANLTCDQLADRRSPVIEFWENKVLRLSGGLEVPGALNWE 119

Query: 220 LALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLY 279
           + LCLL  W++ +FC+WKGV+STGK+VYFTATFP+ +L+VLLVRG+ LPGA  GI +YL 
Sbjct: 120 VTLCLLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGALDGIIYYLK 179

Query: 280 PDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFV 339
           PD ++L  PQVWIDAGTQIFFSYAI LGA+T+LGSYN++  N Y+D ++L  +NSGTSF 
Sbjct: 180 PDWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINSGTSFF 239

Query: 340 SGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLG 399
           +GF +FSILGFMA EQGV I+ VAESGPGLAFIAYP+AVT+MP+   W+ LFF MLLLLG
Sbjct: 240 AGFVVFSILGFMAAEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLLLG 299

Query: 400 LDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFD 459
           LDSQFV VEG IT L+DL P+     ++REI +A  C++ +++ L+MVT+GGMYVFQLFD
Sbjct: 300 LDSQFVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDGGMYVFQLFD 359

Query: 460 YYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGC 519
           YY+ASG  LLW AF+EC V+AW+YG D   D I  MIGYRP PWMK+ W+  TP++C+G 
Sbjct: 360 YYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFFTPLVCMGI 419

Query: 520 FIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRLCQTEGPFLVRVKYL 579
           FIF++V Y PL YN TYVYP W   +GW+ ALSSMLCVPL ++  L + +G    R ++L
Sbjct: 420 FIFNVVYYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAKGTMAERWQHL 479

Query: 580 LTP 582
             P
Sbjct: 480 TQP 482


>gi|92859670 solute carrier family 6 (neurotransmitter transporter,
           glycine), member 5 [Homo sapiens]
          Length = 797

 Score =  522 bits (1344), Expect = e-148
 Identities = 254/580 (43%), Positives = 376/580 (64%), Gaps = 32/580 (5%)

Query: 31  EDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGS 90
           EDE   +   R  WSSK+DF+LS+ G  VGLGNVWRFPYL ++NGGGAFLIPY + L  +
Sbjct: 181 EDEQGDENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALA 240

Query: 91  GLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLF 150
           GLP+FFLE+ +GQ+ S+G ++ W+ I P   G G A ++I  L+ +YY VI+ +  +YLF
Sbjct: 241 GLPIFFLEVSLGQFASQGPVSVWKAI-PALQGCGIAMLIISVLIAIYYNVIICYTLFYLF 299

Query: 151 QSFQKELPWAHCNHSWNTPHCMEDTMR---------------KNKSVWIT----ISSTNF 191
            SF   LPW  CN+ WNTP C + T                 KN +  +T    ++  NF
Sbjct: 300 ASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVISDHPKIQIKNSTFCMTAYPNVTMVNF 359

Query: 192 TSPVI--------EFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTG 243
           TS           E+++  VL +S GI++PG ++W LALCL L W++ +  + KG++++G
Sbjct: 360 TSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLALCLFLAWVIVYASLAKGIKTSG 419

Query: 244 KVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYA 303
           KVVYFTATFP+ +L++LL+RG+TLPGAGAGI +++ P   +L D  VW DA TQIFFS +
Sbjct: 420 KVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLS 479

Query: 304 ICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVA 363
              G + +L SYNK+  N YRD +++ C NS TS  +GF IFS++GFMA E+ V+I +VA
Sbjct: 480 AAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVA 539

Query: 364 ESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLR 423
           + GPG+AF+ YP+A+T +PL  FW+I+FF+MLL LGLD+ F  +E  +TS+ D +P +LR
Sbjct: 540 DQGPGIAFVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLR 599

Query: 424 KGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIY 483
               + +F    C   +++G  M+T+GG+Y+FQL D YAAS   L+ +A FE   I+++Y
Sbjct: 600 T--HKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAAS-YALVIIAIFELVGISYVY 656

Query: 484 GGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAI 543
           G     + IE MIG++P  + K  WA +TP +      FS  ++ P+TY  +Y YPNW++
Sbjct: 657 GLQRFCEDIEMMIGFQPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYG-SYRYPNWSM 715

Query: 544 GLGWSLALSSMLCVPLVIVIRLCQTEGPFLVRVKYLLTPR 583
            LGW +   S++ +P++ VI++    G F+ R+K + +P+
Sbjct: 716 VLGWLMLACSVIWIPIMFVIKMHLAPGRFIERLKLVCSPQ 755


>gi|4557046 solute carrier family 6 member 2 [Homo sapiens]
          Length = 617

 Score =  517 bits (1332), Expect = e-146
 Identities = 258/563 (45%), Positives = 355/563 (63%), Gaps = 11/563 (1%)

Query: 35  EGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPV 94
           +G    RE W  KIDF+LSV G  V L NVWRFPYLCYKNGGGAFLIPY +FL  +G+P+
Sbjct: 50  DGDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPL 109

Query: 95  FFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQ 154
           F++E+ +GQY  EG  T W KICP F G+GYA ++I   +  YY VI+AW+ YYLF SF 
Sbjct: 110 FYMELALGQYNREGAATVW-KICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFT 168

Query: 155 KELPWAHCNHSWNTPHCMEDTMRKNKSVW--ITISSTNFTSPVIEFWERNVLSL--SPGI 210
             LPW  C H+WN+P+C +  +     +      S   FT P  EF+ER VL L  S GI
Sbjct: 169 LNLPWTDCGHTWNSPNCTDPKLLNGSVLGNHTKYSKYKFT-PAAEFYERGVLHLHESSGI 227

Query: 211 DHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGA 270
              G  +W L LCL++V +V +F +WKGV+++GKVV+ TAT P+ +L VLLV G+TLPGA
Sbjct: 228 HDIGLPQWQLLLCLMVVVIVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGA 287

Query: 271 GAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLG 330
             GI  YL+ D  RL++  VWIDA TQIFFS     G + +  SYNK+  N YRD +L  
Sbjct: 288 SNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTS 347

Query: 331 CLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSIL 390
            +N  TSFVSGFAIFSILG+MA E  V+I DVA  G GL FI YP+A++ +   TFW+++
Sbjct: 348 SINCITSFVSGFAIFSILGYMAHEHKVNIEDVATEGAGLVFILYPEAISTLSGSTFWAVV 407

Query: 391 FFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEG 450
           FF+MLL LGLDS    +E  IT L D +    R    R++F   V   ++LL L  +T+G
Sbjct: 408 FFVMLLALGLDSSMGGMEAVITGLADDFQVLKR---HRKLFTFGVTFSTFLLALFCITKG 464

Query: 451 GMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAV 510
           G+YV  L D +AA G  +L+    E   ++W YG D   + I+ M+G+RPG + +  W  
Sbjct: 465 GIYVLTLLDTFAA-GTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFRPGLYWRLCWKF 523

Query: 511 ITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRLCQTEG 570
           ++P   +   + S++ + PLTY+  Y++P WA  +GW +ALSSM+ VP+ ++ +   T+G
Sbjct: 524 VSPAFLLFVVVVSIINFKPLTYD-DYIFPPWANWVGWGIALSSMVLVPIYVIYKFLSTQG 582

Query: 571 PFLVRVKYLLTPREPNRWAVERE 593
               R+ Y +TP   +    +R+
Sbjct: 583 SLWERLAYGITPENEHHLVAQRD 605


>gi|4507041 solute carrier family 6 (neurotransmitter transporter,
           dopamine), member 3 [Homo sapiens]
          Length = 620

 Score =  501 bits (1290), Expect = e-142
 Identities = 248/554 (44%), Positives = 349/554 (62%), Gaps = 9/554 (1%)

Query: 41  REKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEII 100
           RE W  KIDF+LSV G  V L NVWRFPYLCYKNGGGAFL+PY +F+  +G+P+F++E+ 
Sbjct: 60  RETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYMELA 119

Query: 101 IGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA 160
           +GQ+  EG    W KICP+  G+G+  ++I   +  +Y VI+AWA +YLF SF  ELPW 
Sbjct: 120 LGQFNREGAAGVW-KICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSSFTTELPWI 178

Query: 161 HCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSL--SPGIDHPGSLKW 218
           HCN+SWN+P+C +     +      ++ T  T+P  E++ER VL L  S GID  G  +W
Sbjct: 179 HCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQSHGIDDLGPPRW 238

Query: 219 DLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYL 278
            L  CL+LV ++ +F +WKGV+++GKVV+ TAT P+ +L  LL+RG+TLPGA  GI+ YL
Sbjct: 239 QLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPGAIDGIRAYL 298

Query: 279 YPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSF 338
             D  RL +  VWIDA TQ+ FS  +  G + +  SYNK+  N YRD ++   +NS TSF
Sbjct: 299 SVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVTTSINSLTSF 358

Query: 339 VSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLL 398
            SGF +FS LG+MAQ+  V I DVA+ GPGL FI YP+A+  +PL + W+++FFIMLL L
Sbjct: 359 SSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAVVFFIMLLTL 418

Query: 399 GLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLF 458
           G+DS    +E  IT L+D +    R    RE+F  F+   ++LL L  VT GG+YVF L 
Sbjct: 419 GIDSAMGGMESVITGLIDEFQLLHR---HRELFTLFIVLATFLLSLFCVTNGGIYVFTLL 475

Query: 459 DYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVG 518
           D++AA G  +L+    E   +AW YG     D I+ M G RP  + +  W +++P   + 
Sbjct: 476 DHFAA-GTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLF 534

Query: 519 CFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRLCQTEGPFLVRVKY 578
             + S+V + P  Y   Y++P+WA  LGW +A SSM  VP+    + C   G F  ++ Y
Sbjct: 535 VVVVSIVTFRPPHYG-AYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFREKLAY 593

Query: 579 LLTPREPNRWAVER 592
            + P E +R  V+R
Sbjct: 594 AIAP-EKDRELVDR 606


>gi|134304856 solute carrier family 6, member 7 [Homo sapiens]
          Length = 636

 Score =  498 bits (1283), Expect = e-141
 Identities = 247/544 (45%), Positives = 351/544 (64%), Gaps = 7/544 (1%)

Query: 41  REKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEII 100
           R  W+ K+DF+LS  G  VGLGNVWRFPY  Y NGGGAFL+PYF+ L   G+P+FFLE+ 
Sbjct: 37  RGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELS 96

Query: 101 IGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA 160
           +GQ++S G +  W KI PLF G G A ++IV L+ +YY +I+A+  +YLF S   +LPW 
Sbjct: 97  LGQFSSLGPLAVW-KISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLPWE 155

Query: 161 HCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSL--SPGIDHPGSLKW 218
           HC + WNT  C+E  + K+ +  + ++ T   SP  E+W R VL +  S GI  PG ++W
Sbjct: 156 HCGNWWNTELCLEHRVSKDGNGALPLNLTCTVSPSEEYWSRYVLHIQGSQGIGSPGEIRW 215

Query: 219 DLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYL 278
           +L LCLLL W++ F CI KGV+S+GKVVYFTATFP+ +LL+LLVRG+TLPGA  GI+FYL
Sbjct: 216 NLCLCLLLAWVIVFLCILKGVKSSGKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYL 275

Query: 279 YPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSF 338
            P    L   +VWI+A  QIF+S  +  G + +  SYN +  N YRD  ++   N+ TS 
Sbjct: 276 TPQFHHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSI 335

Query: 339 VSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLL 398
           ++GFAIFS+LG+M+QE GV +  VA++GPGLAF+ YP+A+TM+PL  FWS LFF MLL L
Sbjct: 336 LAGFAIFSVLGYMSQELGVPVDQVAKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTL 395

Query: 399 GLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLF 458
           GLDSQF  +E  +T++ D +P +LR   ++ +F   +C   YL+GL + T+GGMY   L 
Sbjct: 396 GLDSQFAFLETIVTAVTDEFPYYLRP--KKAVFSGLICVAMYLMGLILTTDGGMYWLVLL 453

Query: 459 DYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVG 518
           D Y+AS   L+ V    C  +  +YG       I  M+G++PG + +  W  ++P   + 
Sbjct: 454 DDYSAS-FGLMVVVITTCLAVTRVYGIQRFCRDIHMMLGFKPGLYFRACWLFLSPATLLA 512

Query: 519 CFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRLCQTEGPFLVRVKY 578
             ++S+VKY P  Y  +Y +P WA  LG  + L S L +P  +++ + + EG    R++ 
Sbjct: 513 LMVYSIVKYQPSEYG-SYRFPPWAELLGILMGLLSCLMIPAGMLVAVLREEGSLWERLQQ 571

Query: 579 LLTP 582
              P
Sbjct: 572 ASRP 575


>gi|4507043 solute carrier family 6 member 4 [Homo sapiens]
          Length = 630

 Score =  482 bits (1240), Expect = e-136
 Identities = 250/576 (43%), Positives = 351/576 (60%), Gaps = 19/576 (3%)

Query: 20  PSPGKS-------PGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCY 72
           PSPG         P T     AE    +RE W  K+DF+LSV G  V LGNVWRFPY+CY
Sbjct: 51  PSPGAGDDTRHSIPATTTTLVAELHQGERETWGKKVDFLLSVIGYAVDLGNVWRFPYICY 110

Query: 73  KNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVS 132
           +NGGGAFL+PY I     G+P+F++E+ +GQY   G I+ W KICP+F GIGYA  +I  
Sbjct: 111 QNGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWRKICPIFKGIGYAICIIAF 170

Query: 133 LLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFT 192
            +  YY  I+AWA YYL  SF  +LPW  C +SWNT +C  +   ++   W    + + T
Sbjct: 171 YIASYYNTIMAWALYYLISSFTDQLPWTSCKNSWNTGNC-TNYFSEDNITW----TLHST 225

Query: 193 SPVIEFWERNVLSL--SPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTA 250
           SP  EF+ R+VL +  S G+   G + W LALC++L++ V +F IWKGV+++GKVV+ TA
Sbjct: 226 SPAEEFYTRHVLQIHRSKGLQDLGGISWQLALCIMLIFTVIYFSIWKGVKTSGKVVWVTA 285

Query: 251 TFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMT 310
           TFP+ +L VLLVRG TLPGA  G+ FYL P+  +L +  VWIDA  QIFFS     G + 
Sbjct: 286 TFPYIILSVLLVRGATLPGAWRGVLFYLKPNWQKLLETGVWIDAAAQIFFSLGPGFGVLL 345

Query: 311 SLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVA-ESGPGL 369
           +  SYNK+  N Y+D ++   +N  TSFVSGF IF++LG+MA+ +  D+++VA ++GP L
Sbjct: 346 AFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNEDVSEVAKDAGPSL 405

Query: 370 AFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRRE 429
            FI Y +A+  MP  TF++I+FF+ML+ LGLDS F  +EG IT+++D +P    K  RRE
Sbjct: 406 LFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLDEFPHVWAK--RRE 463

Query: 430 IFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLY 489
            F+  V    +   L  +T GG YV +L + Y A+G  +L VA  E   ++W YG     
Sbjct: 464 RFVLAVVITCFFGSLVTLTFGGAYVVKLLEEY-ATGPAVLTVALIEAVAVSWFYGITQFC 522

Query: 490 DGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSL 549
             +++M+G+ PG + +  W  I+P+  +   I S +   P      Y YP W+I LG+ +
Sbjct: 523 RDVKEMLGFSPGWFWRICWVAISPLFLL-FIICSFLMSPPQLRLFQYNYPYWSIILGYCI 581

Query: 550 ALSSMLCVPLVIVIRLCQTEGPFLVRVKYLLTPREP 585
             SS +C+P  I  RL  T G F  R+   +TP  P
Sbjct: 582 GTSSFICIPTYIAYRLIITPGTFKERIIKSITPETP 617


>gi|67782313 solute carrier family 6 member 9 isoform 1 [Homo
           sapiens]
          Length = 652

 Score =  471 bits (1213), Expect = e-133
 Identities = 239/576 (41%), Positives = 356/576 (61%), Gaps = 20/576 (3%)

Query: 14  HKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYK 73
           H  +   SP ++     E     +  +R  W ++I+FVL+  G  VGLGNVWRFPYLCY+
Sbjct: 19  HGPVAPSSPEQNGAVPSEATKRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYR 78

Query: 74  NGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSL 133
           NGGGAF+ PYFI L   G+P+FF+E+  GQ+ S+G +  W +I P+F G+GY  +V+ + 
Sbjct: 79  NGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVW-RISPMFKGVGYGMMVVSTY 137

Query: 134 LNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHC---MEDTMRKNKSVWITISST- 189
           + +YY V++  A YY F S    LPWA+CN+ WNT  C   ++ +   N S    + S  
Sbjct: 138 IGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNL 197

Query: 190 --------NFTSPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRS 241
                     TSP  E+W   VL LS  I + G ++  L  CL + WLV F C+ +GV+S
Sbjct: 198 SHLLNHSLQRTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKS 257

Query: 242 TGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFS 301
           +GKVVYFTATFP+ +L +L VRG+TL GA  GI +YL P   ++ + +VW DA +QIF+S
Sbjct: 258 SGKVVYFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYS 317

Query: 302 YAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIAD 361
                G + ++ SYNK+  N YRD +++   N  TS  +GF IFSILGFMA   GVD++ 
Sbjct: 318 LGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVDVSR 377

Query: 362 VAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPS- 420
           VA+ GPGLAF+AYP+A+T++P+   WS+LFF ML+LLGL +QF  +E  +T++VD   + 
Sbjct: 378 VADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNE 437

Query: 421 -FLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVI 479
             L+K   +      V    +LLG+ + ++ G+Y   L D YAAS   L+ ++   C  I
Sbjct: 438 WILQK---KTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAAS-FSLVVISCIMCVAI 493

Query: 480 AWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYP 539
            +IYG  N +  I+ M+G+ P  + +  W  ++P +     +F++++Y P+TYN  Y YP
Sbjct: 494 MYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTVIQYQPITYNH-YQYP 552

Query: 540 NWAIGLGWSLALSSMLCVPLVIVIRLCQTEGPFLVR 575
            WA+ +G+ +ALSS+LC+PL  + RLC+T+G  L++
Sbjct: 553 GWAVAIGFLMALSSVLCIPLYAMFRLCRTDGDTLLQ 588


>gi|67782317 solute carrier family 6 member 9 isoform 3 [Homo
           sapiens]
          Length = 633

 Score =  469 bits (1206), Expect = e-132
 Identities = 235/550 (42%), Positives = 348/550 (63%), Gaps = 20/550 (3%)

Query: 40  QREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEI 99
           +R  W ++I+FVL+  G  VGLGNVWRFPYLCY+NGGGAF+ PYFI L   G+P+FF+E+
Sbjct: 26  KRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMEL 85

Query: 100 IIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPW 159
             GQ+ S+G +  W +I P+F G+GY  +V+ + + +YY V++  A YY F S    LPW
Sbjct: 86  SFGQFASQGCLGVW-RISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPW 144

Query: 160 AHCNHSWNTPHC---MEDTMRKNKSVWITISST---------NFTSPVIEFWERNVLSLS 207
           A+CN+ WNT  C   ++ +   N S    + S            TSP  E+W   VL LS
Sbjct: 145 AYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLS 204

Query: 208 PGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTL 267
             I + G ++  L  CL + WLV F C+ +GV+S+GKVVYFTATFP+ +L +L VRG+TL
Sbjct: 205 DDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTL 264

Query: 268 PGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCM 327
            GA  GI +YL P   ++ + +VW DA +QIF+S     G + ++ SYNK+  N YRD +
Sbjct: 265 EGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSV 324

Query: 328 LLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFW 387
           ++   N  TS  +GF IFSILGFMA   GVD++ VA+ GPGLAF+AYP+A+T++P+   W
Sbjct: 325 IISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLW 384

Query: 388 SILFFIMLLLLGLDSQFVEVEGQITSLVDLYPS--FLRKGYRREIFIAFVCSISYLLGLT 445
           S+LFF ML+LLGL +QF  +E  +T++VD   +   L+K   +      V    +LLG+ 
Sbjct: 385 SLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQK---KTYVTLGVAVAGFLLGIP 441

Query: 446 MVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMK 505
           + ++ G+Y   L D YAAS   L+ ++   C  I +IYG  N +  I+ M+G+ P  + +
Sbjct: 442 LTSQAGIYWLLLMDNYAAS-FSLVVISCIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQ 500

Query: 506 YSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRL 565
             W  ++P +     +F++++Y P+TYN  Y YP WA+ +G+ +ALSS+LC+PL  + RL
Sbjct: 501 ICWRFVSPAIIFFILVFTVIQYQPITYNH-YQYPGWAVAIGFLMALSSVLCIPLYAMFRL 559

Query: 566 CQTEGPFLVR 575
           C+T+G  L++
Sbjct: 560 CRTDGDTLLQ 569


>gi|67782315 solute carrier family 6 member 9 isoform 2 [Homo
           sapiens]
          Length = 706

 Score =  469 bits (1206), Expect = e-132
 Identities = 235/550 (42%), Positives = 348/550 (63%), Gaps = 20/550 (3%)

Query: 40  QREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEI 99
           +R  W ++I+FVL+  G  VGLGNVWRFPYLCY+NGGGAF+ PYFI L   G+P+FF+E+
Sbjct: 99  KRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMEL 158

Query: 100 IIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPW 159
             GQ+ S+G +  W +I P+F G+GY  +V+ + + +YY V++  A YY F S    LPW
Sbjct: 159 SFGQFASQGCLGVW-RISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPW 217

Query: 160 AHCNHSWNTPHC---MEDTMRKNKSVWITISST---------NFTSPVIEFWERNVLSLS 207
           A+CN+ WNT  C   ++ +   N S    + S            TSP  E+W   VL LS
Sbjct: 218 AYCNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLS 277

Query: 208 PGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTL 267
             I + G ++  L  CL + WLV F C+ +GV+S+GKVVYFTATFP+ +L +L VRG+TL
Sbjct: 278 DDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTL 337

Query: 268 PGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCM 327
            GA  GI +YL P   ++ + +VW DA +QIF+S     G + ++ SYNK+  N YRD +
Sbjct: 338 EGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSV 397

Query: 328 LLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFW 387
           ++   N  TS  +GF IFSILGFMA   GVD++ VA+ GPGLAF+AYP+A+T++P+   W
Sbjct: 398 IISITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLW 457

Query: 388 SILFFIMLLLLGLDSQFVEVEGQITSLVDLYPS--FLRKGYRREIFIAFVCSISYLLGLT 445
           S+LFF ML+LLGL +QF  +E  +T++VD   +   L+K   +      V    +LLG+ 
Sbjct: 458 SLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQK---KTYVTLGVAVAGFLLGIP 514

Query: 446 MVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMK 505
           + ++ G+Y   L D YAAS   L+ ++   C  I +IYG  N +  I+ M+G+ P  + +
Sbjct: 515 LTSQAGIYWLLLMDNYAAS-FSLVVISCIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQ 573

Query: 506 YSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRL 565
             W  ++P +     +F++++Y P+TYN  Y YP WA+ +G+ +ALSS+LC+PL  + RL
Sbjct: 574 ICWRFVSPAIIFFILVFTVIQYQPITYNH-YQYPGWAVAIGFLMALSSVLCIPLYAMFRL 632

Query: 566 CQTEGPFLVR 575
           C+T+G  L++
Sbjct: 633 CRTDGDTLLQ 642


>gi|6005715 solute carrier family 6 (amino acid transporter), member
           14 [Homo sapiens]
          Length = 642

 Score =  456 bits (1172), Expect = e-128
 Identities = 244/570 (42%), Positives = 349/570 (61%), Gaps = 43/570 (7%)

Query: 41  REKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEII 100
           R  WS K D++LS+ G  VGLGNVWRFPYL Y NGGGAFLIPY I L  +GLP+FFLE  
Sbjct: 36  RGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLECS 95

Query: 101 IGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA 160
           +GQ+ S G ++ W +I PLF G+G   V+I   + +YY VI+A++ YY+F SFQ ELPW 
Sbjct: 96  LGQFASLGPVSVW-RILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSELPWK 154

Query: 161 HCNHSWNTPHC-----------------MEDTMRKNKSVWITISSTNFTS---------- 193
           +C+ SW+  +C                 +++ ++ NKS W+ I+  NFT           
Sbjct: 155 NCS-SWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKS-WVDIN--NFTCINGSEIYQPG 210

Query: 194 --PVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTAT 251
             P  ++W +  L  S G++  G + W LALCLLL WL+    ++KG++S+GKVVYFTA 
Sbjct: 211 QLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTAL 270

Query: 252 FPFAMLLVLLVRGLTLPGAGAGIKFYL--YPDITRLEDPQVWIDAGTQIFFSYAICLGAM 309
           FP+ +LL+LLVRG TL GA  GI +Y+    + T+L++ +VW DA TQIF+S ++  G +
Sbjct: 271 FPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGGL 330

Query: 310 TSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGL 369
            +L SYNK+K N + D +++   N  TS  +GFAIFSILG MA   G +++ V +SG  L
Sbjct: 331 VALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFDL 390

Query: 370 AFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRRE 429
           AFIAYP+A+  +P   FWSILFF MLL LGLDSQF  +E   T++ DL+P  ++K   R 
Sbjct: 391 AFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKK--MRV 448

Query: 430 IFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLY 489
                 C + +LLGL  VT+ G+Y   L D++ A G  +L  A  E   I WIYGG+   
Sbjct: 449 PITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCA-GWGILIAAILELVGIIWIYGGNRFI 507

Query: 490 DGIEDMIGYRP---GPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLG 546
           +  E MIG +      W +  W VITP+L +  FI+SLV++    Y     YP+W + LG
Sbjct: 508 EDTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYG-AIPYPDWGVALG 566

Query: 547 WSLALSSMLCVPLVIVIRLCQTEGPFLVRV 576
           W + +  ++ +P++ +I++ Q +G    R+
Sbjct: 567 WCMIVFCIIWIPIMAIIKIIQAKGNIFQRL 596


>gi|197276625 solute carrier family 6 (neurotransmitter transporter,
           taurine), member 6 isoform b [Homo sapiens]
          Length = 200

 Score =  429 bits (1104), Expect = e-120
 Identities = 200/200 (100%), Positives = 200/200 (100%)

Query: 1   MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVG 60
           MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVG
Sbjct: 1   MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVG 60

Query: 61  LGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLF 120
           LGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLF
Sbjct: 61  LGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLF 120

Query: 121 SGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNK 180
           SGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNK
Sbjct: 121 SGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNK 180

Query: 181 SVWITISSTNFTSPVIEFWE 200
           SVWITISSTNFTSPVIEFWE
Sbjct: 181 SVWITISSTNFTSPVIEFWE 200


>gi|51468073 solute carrier family 6, member 19 [Homo sapiens]
          Length = 634

 Score =  366 bits (940), Expect = e-101
 Identities = 210/613 (34%), Positives = 309/613 (50%), Gaps = 91/613 (14%)

Query: 28  TRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFL 87
           T  ++EA  +P    KW +K  ++L+  G  VGLGNVWRFPYLC  +GGGAF+IP+ I L
Sbjct: 23  TIEQEEASSRP----KWDNKAQYMLTCLGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILL 78

Query: 88  FGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATY 147
              G+P+ +LE  IGQ    G +  W  I P   G+G AS++   ++ +YY  I++W  +
Sbjct: 79  VLEGIPLLYLEFAIGQRLRRGSLGVWSSIHPALKGLGLASMLTSFMVGLYYNTIISWIMW 138

Query: 148 YLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSLS 207
           YLF SFQ+ LPW+ C  + N    +++  R              +SPV  FW R  L++S
Sbjct: 139 YLFNSFQEPLPWSDCPLNENQTGYVDECAR--------------SSPVDYFWYRETLNIS 184

Query: 208 PGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTL 267
             I   GS++W + LCL   W V + C  +G+ +TGK VY T+T P+ +L + L+RGLTL
Sbjct: 185 TSISDSGSIQWWMLLCLACAWSVLYMCTIRGIETTGKAVYITSTLPYVVLTIFLIRGLTL 244

Query: 268 PGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCM 327
            GA  GI F   P++T L  P  W+DAG Q+FFS+++  G + S  SYN    N  +D +
Sbjct: 245 KGATNGIVFLFTPNVTELAQPDTWLDAGAQVFFSFSLAFGGLISFSSYNSVHNNCEKDSV 304

Query: 328 LLGCLNSGTSFVSGFAIFSILGFMA---------------------------QEQGVDI- 359
           ++  +N  TS      ++S++GF A                           QE  VD+ 
Sbjct: 305 IVSIINGFTSVYVAIVVYSVIGFRATQRYDDCFSTNILTLINGFDLPEGNVTQENFVDMQ 364

Query: 360 ------------------ADV------AESGPGLAFIAYPKAVTMMPLPTFWSILFFIML 395
                              D+      A  G GLAFI + +A+T MPL   WS+LFFIML
Sbjct: 365 QRCNASDPAAYAQLVFQTCDINAFLSEAVEGTGLAFIVFTEAITKMPLSPLWSVLFFIML 424

Query: 396 LLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVF 455
             LGL S F  +EG +  L DL    +   + +E+    +C  ++L+G       G Y  
Sbjct: 425 FCLGLSSMFGNMEGVVVPLQDL--RVIPPKWPKEVLTGLICLGTFLIGFIFTLNSGQYWL 482

Query: 456 QLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVL 515
            L D YA S + LL +AF E F + ++YG D     IE MIG++P  + + +W V++P+L
Sbjct: 483 SLLDSYAGS-IPLLIIAFCEMFSVVYVYGVDRFNKDIEFMIGHKPNIFWQVTWRVVSPLL 541

Query: 516 CVGCFIFSLVKYV--PLTY------------NKTYVYPNWAIGLGWSLALSSMLCVPLVI 561
            +  F+F  V  V   LTY            ++   YPNW   +   +A    L +P   
Sbjct: 542 MLIIFLFFFVVEVSQELTYSIWDPGYEEFPKSQKISYPNWVYVVVVIVAGVPSLTIPGYA 601

Query: 562 VIRL----CQTEG 570
           + +L    CQ  G
Sbjct: 602 IYKLIRNHCQKPG 614


>gi|194018524 solute carrier family 6, member 18 [Homo sapiens]
          Length = 628

 Score =  353 bits (906), Expect = 3e-97
 Identities = 205/601 (34%), Positives = 303/601 (50%), Gaps = 82/601 (13%)

Query: 30  PEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFG 89
           P+  A     +R KW +K  ++LS  G  VGLGN+WRFPYLC   GGGAFLIPY I L  
Sbjct: 7   PDPAACDLGDERPKWDNKAQYLLSCTGFAVGLGNIWRFPYLCQTYGGGAFLIPYVIALVF 66

Query: 90  SGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYL 149
            G+P+F +E+ IGQ   +G +  W  I P  SG+G   V +  L+++YY  I+AW  +YL
Sbjct: 67  EGIPIFHVELAIGQRLRKGSVGVWTAISPYLSGVGLGCVTLSFLISLYYNTIVAWVLWYL 126

Query: 150 FQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSLSPG 209
             SFQ  LPW+ C    N    +E+                 +S V  FW R  L+++  
Sbjct: 127 LNSFQHPLPWSSCPPDLNRTGFVEECQG--------------SSAVSYFWYRQTLNITAD 172

Query: 210 IDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPG 269
           I+  GS++W L +CL   W V + C+ +G+ +TGKV+YFTA FP+ +L + L+RGLTLPG
Sbjct: 173 INDSGSIQWWLLICLAASWAVVYMCVIRGIETTGKVIYFTALFPYLVLTIFLIRGLTLPG 232

Query: 270 AGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLL 329
           A  G+ +   P++  L++P+VW+DA TQIFFS ++  G   +  SYN  + +  +D +++
Sbjct: 233 ATKGLIYLFTPNMHILQNPRVWLDAATQIFFSLSLAFGGHIAFASYNSPRNDCQKDAVVI 292

Query: 330 GCLNSGTSFVSGFAIFSILGFMA---------------------QEQGV----------- 357
             +N  TS  +  A+FS+LGF A                      EQ +           
Sbjct: 293 ALVNRMTSLYASIAVFSVLGFKATNDYEHCLDRNILSLINDFDFPEQSISRDDYPAVLMH 352

Query: 358 --------------------DIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLL 397
                               D  D + SGPGLAF+ + +    MP    W++LFF ML  
Sbjct: 353 LNATWPKRVAQLPLKACLLEDFLDKSASGPGLAFVVFTETDLHMPGAPVWAMLFFGMLFT 412

Query: 398 LGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQL 457
           LGL + F  VE  IT L+D+    L +   +E     VC + +L       + G Y  ++
Sbjct: 413 LGLSTMFGTVEAVITPLLDV--GVLPRWVPKEALTGLVCLVCFLSATCFTLQSGNYWLEI 470

Query: 458 FDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITP-VLC 516
           FD +AAS   LL +AF E   + ++YG     D I  M G RP P+ + +W V++P +L 
Sbjct: 471 FDNFAAS-PNLLMLAFLEVVGVVYVYGMKRFCDDIAWMTGRRPSPYWRLTWRVVSPLLLT 529

Query: 517 VGCFIFSLVKYVPLTY---NKTY---------VYPNWAIGLGWSLALSSMLCVPLVIVIR 564
           +      L+ + PL Y   N  Y         +YP WA      L+L  +L VP+  + +
Sbjct: 530 IFVAYIILLFWKPLRYKAWNPKYELFPSRQEKLYPGWARAACVLLSLLPVLWVPVAALAQ 589

Query: 565 L 565
           L
Sbjct: 590 L 590


>gi|11181770 solute carrier family 6, member 20 isoform 1 [Homo
           sapiens]
          Length = 592

 Score =  341 bits (874), Expect = 1e-93
 Identities = 201/589 (34%), Positives = 288/589 (48%), Gaps = 91/589 (15%)

Query: 41  REKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEII 100
           R  W++ + FV +     VGLGNVWRFPYLC   GGG+FL+PY I L   G+P+ +LE+ 
Sbjct: 5   RPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELA 64

Query: 101 IGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA 160
           +GQ   +G I  W  I P  SG+G ASVV+   L++YY VI AWA +YLF SFQ  LPW+
Sbjct: 65  VGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWS 124

Query: 161 HC----NHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSL 216
            C    NH+     C +             SST +      FW R  L++SP +   G +
Sbjct: 125 VCPLNGNHTGYDEECEK------------ASSTQY------FWYRKTLNISPSLQENGGV 166

Query: 217 KWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKF 276
           +W+ ALCLLL WLV + CI +G  STGKVVYFTA+ P+ +L++ L+RGLTL GA  G+ +
Sbjct: 167 QWEPALCLLLAWLVVYLCILRGTESTGKVVYFTASLPYCVLIIYLIRGLTLHGATNGLMY 226

Query: 277 YLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGT 336
              P I +L +P+ WI+A TQIFFS  +  G++ +  SYN+   N  +  +++  +NS T
Sbjct: 227 MFTPKIEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINSFT 286

Query: 337 SFVSGFAIFSILGFMAQ--------------------EQGVDIADVAESGPGLAFIAYP- 375
           S  +    FSI GF A                     E G   A   E   G    AYP 
Sbjct: 287 SIFASIVTFSIYGFKATFNYENCLKKVSLLLTNTFDLEDGFLTASNLEQVKGYLASAYPS 346

Query: 376 ---------------------------------KAVTMMPLPTFWSILFFIMLLLLGLDS 402
                                            +A+  M +   WS+L+F MLL+LG+ S
Sbjct: 347 KYSEMFPQIKNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGS 406

Query: 403 QFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYA 462
                   +T L D     +     +E     VC ++  +G+    E G Y F +F+ YA
Sbjct: 407 MLGNTAAILTPLTD--SKIISSHLPKEAISGLVCLVNCAIGMVFTMEAGNYWFDIFNDYA 464

Query: 463 ASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIF 522
           A+ + LL +   E   + ++YG       ++ M G     + K  WA ++P+L V  F+F
Sbjct: 465 AT-LSLLLIVLVETIAVCYVYGLRRFESDLKAMTGRAVSWYWKVMWAGVSPLLIVSLFVF 523

Query: 523 SLVKYV---PLTYNK---------TYVYPNWAIGLGWSLALSSMLCVPL 559
            L  Y+    L Y           T  YP +A+ +   L  SS +C+PL
Sbjct: 524 YLSDYILTGTLKYQAWDASQGQLVTKDYPAYALAVIGLLVASSTMCIPL 572


>gi|12408638 solute carrier family 6, member 20 isoform 2 [Homo
           sapiens]
          Length = 555

 Score =  285 bits (728), Expect = 1e-76
 Identities = 183/589 (31%), Positives = 262/589 (44%), Gaps = 128/589 (21%)

Query: 41  REKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEII 100
           R  W++ + FV +     VGLGNVWRFPYLC   GGG+FL+PY I L   G+P+ +LE+ 
Sbjct: 5   RPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELA 64

Query: 101 IGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA 160
           +GQ   +G I  W  I P  SG+G ASVV+   L++YY VI AWA +YLF SFQ  LPW+
Sbjct: 65  VGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWS 124

Query: 161 HC----NHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSL 216
            C    NH+     C +             SST +      FW R  L++SP +   G +
Sbjct: 125 VCPLNGNHTGYDEECEK------------ASSTQY------FWYRKTLNISPSLQENGGV 166

Query: 217 KWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKF 276
           +W+ ALCLLL WLV + CI +G  STGK                                
Sbjct: 167 QWEPALCLLLAWLVVYLCILRGTESTGK-------------------------------- 194

Query: 277 YLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGT 336
                I +L +P+ WI+A TQIFFS  +  G++ +  SYN+   N  +  +++  +NS T
Sbjct: 195 -----IEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINSFT 249

Query: 337 SFVSGFAIFSILGFMAQ--------------------EQGVDIADVAESGPGLAFIAYP- 375
           S  +    FSI GF A                     E G   A   E   G    AYP 
Sbjct: 250 SIFASIVTFSIYGFKATFNYENCLKKVSLLLTNTFDLEDGFLTASNLEQVKGYLASAYPS 309

Query: 376 ---------------------------------KAVTMMPLPTFWSILFFIMLLLLGLDS 402
                                            +A+  M +   WS+L+F MLL+LG+ S
Sbjct: 310 KYSEMFPQIKNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGS 369

Query: 403 QFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYA 462
                   +T L D     +     +E     VC ++  +G+    E G Y F +F+ YA
Sbjct: 370 MLGNTAAILTPLTD--SKIISSHLPKEAISGLVCLVNCAIGMVFTMEAGNYWFDIFNDYA 427

Query: 463 ASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIF 522
           A+ + LL +   E   + ++YG       ++ M G     + K  WA ++P+L V  F+F
Sbjct: 428 AT-LSLLLIVLVETIAVCYVYGLRRFESDLKAMTGRAVSWYWKVMWAGVSPLLIVSLFVF 486

Query: 523 SLVKYV---PLTYNK---------TYVYPNWAIGLGWSLALSSMLCVPL 559
            L  Y+    L Y           T  YP +A+ +   L  SS +C+PL
Sbjct: 487 YLSDYILTGTLKYQAWDASQGQLVTKDYPAYALAVIGLLVASSTMCIPL 535


>gi|58219014 solute carrier family 6, member 17 [Homo sapiens]
          Length = 727

 Score =  275 bits (702), Expect = 1e-73
 Identities = 132/341 (38%), Positives = 198/341 (58%), Gaps = 13/341 (3%)

Query: 12  DFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLC 71
           D+ + +L  + G++ G +   E E     R  W+SK+ ++L+  G  VGLGN+WRFPYLC
Sbjct: 32  DYKQSVLNVA-GEAGGKQKAVEEELDAEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLC 90

Query: 72  YKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIV 131
            KNGGGA+L+PY + L   G+P+FFLE+ +GQ    G I  W  ICP   GIG++S ++ 
Sbjct: 91  QKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWHYICPRLGGIGFSSCIVC 150

Query: 132 SLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNKSVWITISSTNF 191
             + +YY VI+ W+ +Y F+SFQ  LPW+ C             + +N SV +  +    
Sbjct: 151 LFVGLYYNVIIGWSIFYFFKSFQYPLPWSEC------------PVVRNGSVAVVEAECEK 198

Query: 192 TSPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTAT 251
           +S    FW R  L +S  I   G L W + LCLL+ W +    + KG++S+GKV+YF++ 
Sbjct: 199 SSATTYFWYREALDISDSISESGGLNWKMTLCLLVAWSIVGMAVVKGIQSSGKVMYFSSL 258

Query: 252 FPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTS 311
           FP+ +L   LVRGL L GA  GI     P + ++ DPQVW +A TQ+FF+  +  G + +
Sbjct: 259 FPYVVLACFLVRGLLLRGAVDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIA 318

Query: 312 LGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMA 352
             SYNK   N + D  L+  +N  TS ++   +F++LGF A
Sbjct: 319 FSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLGFKA 359


>gi|33354281 solute carrier family 6, member 15 isoform 1 [Homo
           sapiens]
          Length = 730

 Score =  256 bits (654), Expect = 4e-68
 Identities = 122/327 (37%), Positives = 189/327 (57%), Gaps = 24/327 (7%)

Query: 32  DEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSG 91
           +E      +R  W+SK+ ++L+  G  VGLGNVWRFPYLC KNGGGA+L+PY I L   G
Sbjct: 52  EEGSEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIG 111

Query: 92  LPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQ 151
           +P+FFLE+ +GQ    G I  W  I P   GIG+AS V+   + +YY VI+ W+ +Y  Q
Sbjct: 112 IPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQ 171

Query: 152 SFQKELPWAHC------NHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLS 205
           SFQ+ LPW  C      +H++  P C +             S+T +      +W R  L+
Sbjct: 172 SFQQPLPWDQCPLVKNASHTFVEPECEQS------------SATTY------YWYREALN 213

Query: 206 LSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGL 265
           +S  I   G L W + +CLL  W++    + KG++S+GK++YF++ FP+ +L+  L+R  
Sbjct: 214 ISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKIIYFSSLFPYVVLICFLIRAF 273

Query: 266 TLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRD 325
            L G+  GI+    P +  + +P+VW +A TQ+FF+  +  G + +  SYNK   N + D
Sbjct: 274 LLNGSIDGIRHMFTPKLEIMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFD 333

Query: 326 CMLLGCLNSGTSFVSGFAIFSILGFMA 352
            +L+  +N  TS ++   +F++LGF A
Sbjct: 334 AVLVSFINFFTSVLATLVVFAVLGFKA 360



 Score =  127 bits (319), Expect = 3e-29
 Identities = 72/213 (33%), Positives = 115/213 (53%), Gaps = 18/213 (8%)

Query: 363 AESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFL 422
           A  G GLAFIA+ +A+T  P   FWS++FF+ML+ LGL S F  +EG +T +VD +    
Sbjct: 435 AVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIEGIVTPIVDTFK--- 491

Query: 423 RKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWI 482
               R+EI     C +++ +GL  V   G Y   +FD Y+A+ + LL V   E   + ++
Sbjct: 492 ---VRKEILTVICCLLAFCIGLIFVQRSGNYFVTMFDDYSAT-LPLLIVVILENIAVCFV 547

Query: 483 YGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVK--YVPLTYN------- 533
           YG D   + ++DM+G+ P  +  Y W  I+P++ +   I S+V     P  YN       
Sbjct: 548 YGIDKFMEDLKDMLGFAPSRYYYYMWKYISPLMLLSLLIASVVNMGLSPPGYNAWIEDKA 607

Query: 534 --KTYVYPNWAIGLGWSLALSSMLCVPLVIVIR 564
             +   YP W + +  SL + ++L VP+V ++R
Sbjct: 608 SEEFLSYPTWGLVVCVSLVVFAILPVPVVFIVR 640


>gi|226437581 solute carrier family 6, member 15 isoform 3 [Homo
           sapiens]
          Length = 623

 Score =  188 bits (478), Expect = 1e-47
 Identities = 91/268 (33%), Positives = 149/268 (55%), Gaps = 24/268 (8%)

Query: 91  GLPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLF 150
           G+P+FFLE+ +GQ    G I  W  I P   GIG+AS V+   + +YY VI+ W+ +Y  
Sbjct: 4   GIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFS 63

Query: 151 QSFQKELPWAHC------NHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVL 204
           QSFQ+ LPW  C      +H++  P C +             S+T +      +W R  L
Sbjct: 64  QSFQQPLPWDQCPLVKNASHTFVEPECEQS------------SATTY------YWYREAL 105

Query: 205 SLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRG 264
           ++S  I   G L W + +CLL  W++    + KG++S+GK++YF++ FP+ +L+  L+R 
Sbjct: 106 NISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKIIYFSSLFPYVVLICFLIRA 165

Query: 265 LTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYR 324
             L G+  GI+    P +  + +P+VW +A TQ+FF+  +  G + +  SYNK   N + 
Sbjct: 166 FLLNGSIDGIRHMFTPKLEIMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHF 225

Query: 325 DCMLLGCLNSGTSFVSGFAIFSILGFMA 352
           D +L+  +N  TS ++   +F++LGF A
Sbjct: 226 DAVLVSFINFFTSVLATLVVFAVLGFKA 253



 Score =  127 bits (319), Expect = 3e-29
 Identities = 72/213 (33%), Positives = 115/213 (53%), Gaps = 18/213 (8%)

Query: 363 AESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPSFL 422
           A  G GLAFIA+ +A+T  P   FWS++FF+ML+ LGL S F  +EG +T +VD +    
Sbjct: 328 AVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIEGIVTPIVDTFK--- 384

Query: 423 RKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIAWI 482
               R+EI     C +++ +GL  V   G Y   +FD Y+A+ + LL V   E   + ++
Sbjct: 385 ---VRKEILTVICCLLAFCIGLIFVQRSGNYFVTMFDDYSAT-LPLLIVVILENIAVCFV 440

Query: 483 YGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVK--YVPLTYN------- 533
           YG D   + ++DM+G+ P  +  Y W  I+P++ +   I S+V     P  YN       
Sbjct: 441 YGIDKFMEDLKDMLGFAPSRYYYYMWKYISPLMLLSLLIASVVNMGLSPPGYNAWIEDKA 500

Query: 534 --KTYVYPNWAIGLGWSLALSSMLCVPLVIVIR 564
             +   YP W + +  SL + ++L VP+V ++R
Sbjct: 501 SEEFLSYPTWGLVVCVSLVVFAILPVPVVFIVR 533


>gi|21361693 solute carrier family 6, member 15 isoform 2 [Homo
           sapiens]
          Length = 289

 Score =  183 bits (465), Expect = 4e-46
 Identities = 91/236 (38%), Positives = 133/236 (56%), Gaps = 27/236 (11%)

Query: 32  DEAEGKPPQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSG 91
           +E      +R  W+SK+ ++L+  G  VGLGNVWRFPYLC KNGGGA+L+PY I L   G
Sbjct: 52  EEGSEVEDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIG 111

Query: 92  LPVFFLEIIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQ 151
           +P+FFLE+ +GQ    G I  W  I P   GIG+AS V+   + +YY VI+ W+ +Y  Q
Sbjct: 112 IPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQ 171

Query: 152 SFQKELPWAHC------NHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLS 205
           SFQ+ LPW  C      +H++  P C +             S+T +      +W R  L+
Sbjct: 172 SFQQPLPWDQCPLVKNASHTFVEPECEQS------------SATTY------YWYREALN 213

Query: 206 LSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLL 261
           +S  I   G L W + +CLL  W++    + KG++S+GKV   +   PF +LL+ +
Sbjct: 214 ISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLITI 266


>gi|55749589 solute carrier family 6, member 16 [Homo sapiens]
          Length = 736

 Score =  171 bits (432), Expect = 2e-42
 Identities = 102/316 (32%), Positives = 154/316 (48%), Gaps = 22/316 (6%)

Query: 41  REKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEII 100
           R  WSSK +++L+  G  +    +WRF YL   +GG +F   Y   LF  G+P+ FLE+ 
Sbjct: 103 RPFWSSKTEYILAQVGFSMKPSCLWRFAYLWLNSGGCSFAAIYIFMLFLVGVPLLFLEMA 162

Query: 101 IGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA 160
            GQ   +GG+  W+ I P   G+GY+S ++  +L +Y+ V+ +W  +Y+ QSFQ  +PW 
Sbjct: 163 AGQSMRQGGMGVWKIIAPWIGGVGYSSFMVCFILGLYFNVVNSWIIFYMSQSFQFPVPWE 222

Query: 161 HC----NHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSL 216
            C    N S   P C                    T+P I FW +  L  S  I+  GS 
Sbjct: 223 KCPLTMNSSGFDPECER------------------TTPSIYFWYQQALKASDRIEDGGSP 264

Query: 217 KWDLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKF 276
            + L L   L W +    +  G++STGKV+Y     P  +++   +R L L GA  G++ 
Sbjct: 265 VYSLVLPFFLCWCLVGAFMINGLKSTGKVIYVLVLLPCFIIVGFFIRTLLLEGAKFGLQQ 324

Query: 277 YLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGT 336
            +   I+ + +  VW  AG Q+  +  I LG++ SL SY     N   D  L+  +N  T
Sbjct: 325 LVVAKISDVYNMSVWSLAGGQVLSNTGIGLGSVASLASYMPQSNNCLSDAFLVSVINLLT 384

Query: 337 SFVSGFAIFSILGFMA 352
             V     F +LGF A
Sbjct: 385 LLVFTSFNFCVLGFWA 400


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.143    0.475 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,692,732
Number of Sequences: 37866
Number of extensions: 1190981
Number of successful extensions: 3508
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 3371
Number of HSP's gapped (non-prelim): 44
length of query: 620
length of database: 18,247,518
effective HSP length: 108
effective length of query: 512
effective length of database: 14,157,990
effective search space: 7248890880
effective search space used: 7248890880
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.