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Search of human proteins with 19718731
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
(1362 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 2801 0.0
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ... 1461 0.0
gi|11067749 bromodomain containing protein 3 [Homo sapiens] 751 0.0
gi|164419758 bromodomain containing 2 [Homo sapiens] 731 0.0
gi|4826806 bromodomain containing 2 [Homo sapiens] 731 0.0
gi|46399200 testis-specific bromodomain protein [Homo sapiens] 595 e-169
gi|46399198 testis-specific bromodomain protein [Homo sapiens] 595 e-169
gi|151301053 RNA binding motif protein 33 [Homo sapiens] 160 1e-38
gi|47132519 Ras association and pleckstrin homology domains 1 is... 150 8e-36
gi|110349719 titin isoform N2-A [Homo sapiens] 149 2e-35
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 131 5e-30
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 131 5e-30
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 131 5e-30
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 130 9e-30
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 125 2e-28
gi|160707881 formin 2 [Homo sapiens] 125 3e-28
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 123 1e-27
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 123 1e-27
gi|150417989 cyclin K isoform 1 [Homo sapiens] 121 5e-27
gi|150170670 piccolo isoform 2 [Homo sapiens] 119 2e-26
gi|150378539 piccolo isoform 1 [Homo sapiens] 119 2e-26
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 118 4e-26
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 118 4e-26
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 116 2e-25
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 115 4e-25
gi|55750053 atrophin-1 [Homo sapiens] 111 5e-24
gi|55750041 atrophin-1 [Homo sapiens] 111 5e-24
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 110 9e-24
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 110 9e-24
gi|146134388 YLP motif containing 1 [Homo sapiens] 107 1e-22
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 2801 bits (7261), Expect = 0.0
Identities = 1362/1362 (100%), Positives = 1362/1362 (100%)
Query: 1 MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQT 60
MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQT
Sbjct: 1 MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQT 60
Query: 61 NQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYW 120
NQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYW
Sbjct: 61 NQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYW 120
Query: 121 NAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRG 180
NAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRG
Sbjct: 121 NAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRG 180
Query: 181 RGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMT 240
RGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMT
Sbjct: 181 RGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMT 240
Query: 241 VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI 300
VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI
Sbjct: 241 VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI 300
Query: 301 DPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGI 360
DPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGI
Sbjct: 301 DPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGI 360
Query: 361 LKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGA 420
LKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGA
Sbjct: 361 LKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGA 420
Query: 421 DVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVV 480
DVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVV
Sbjct: 421 DVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVV 480
Query: 481 APPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKE 540
APPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKE
Sbjct: 481 APPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKE 540
Query: 541 KDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYE 600
KDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYE
Sbjct: 541 KDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYE 600
Query: 601 SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLK 660
SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLK
Sbjct: 601 SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLK 660
Query: 661 PSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETE 720
PSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETE
Sbjct: 661 PSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETE 720
Query: 721 MAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPP 780
MAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPP
Sbjct: 721 MAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPP 780
Query: 781 PPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLP 840
PPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLP
Sbjct: 781 PPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLP 840
Query: 841 QPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLL 900
QPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLL
Sbjct: 841 QPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLL 900
Query: 901 PQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPP 960
PQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPP
Sbjct: 901 PQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPP 960
Query: 961 PPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPP 1020
PPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPP
Sbjct: 961 PPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPP 1020
Query: 1021 HPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLT 1080
HPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLT
Sbjct: 1021 HPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLT 1080
Query: 1081 HQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESI 1140
HQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESI
Sbjct: 1081 HQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESI 1140
Query: 1141 KAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMG 1200
KAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMG
Sbjct: 1141 KAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMG 1200
Query: 1201 SWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERM 1260
SWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERM
Sbjct: 1201 SWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERM 1260
Query: 1261 RSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSM 1320
RSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSM
Sbjct: 1261 RSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSM 1320
Query: 1321 LDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF 1362
LDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF
Sbjct: 1321 LDQQRELARKREQERRRREAMAATIDMNFQSDLLSIFEENLF 1362
>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
sapiens]
Length = 722
Score = 1461 bits (3782), Expect = 0.0
Identities = 719/719 (100%), Positives = 719/719 (100%)
Query: 1 MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQT 60
MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQT
Sbjct: 1 MSAESGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQT 60
Query: 61 NQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYW 120
NQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYW
Sbjct: 61 NQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYW 120
Query: 121 NAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRG 180
NAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRG
Sbjct: 121 NAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRG 180
Query: 181 RGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMT 240
RGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMT
Sbjct: 181 RGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMT 240
Query: 241 VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI 300
VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI
Sbjct: 241 VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI 300
Query: 301 DPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGI 360
DPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGI
Sbjct: 301 DPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGI 360
Query: 361 LKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGA 420
LKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGA
Sbjct: 361 LKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGA 420
Query: 421 DVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVV 480
DVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVV
Sbjct: 421 DVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVV 480
Query: 481 APPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKE 540
APPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKE
Sbjct: 481 APPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKE 540
Query: 541 KDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYE 600
KDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYE
Sbjct: 541 KDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYE 600
Query: 601 SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLK 660
SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLK
Sbjct: 601 SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLK 660
Query: 661 PSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSET 719
PSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSET
Sbjct: 661 PSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSET 719
Score = 63.2 bits (152), Expect = 2e-09
Identities = 87/371 (23%), Positives = 142/371 (38%), Gaps = 24/371 (6%)
Query: 974 PPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQP 1033
PP PQP PPP Q P P P + T + PPQ Q P P P Q PPP P
Sbjct: 205 PPQTQTPQPNPPPVQA-TPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAP 263
Query: 1034 AKPQQVIQHHHSPRHHKSDPYST--GHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQP 1091
A Q +Q H P T G R+A + + + SL PP+
Sbjct: 264 A--PQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSL----PPEPKTTK 317
Query: 1092 KKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPE 1151
Q ++ V+P P V + + H +S S L+ E P
Sbjct: 318 LGQRRESSRPVKP-PKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPF 376
Query: 1152 MKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKK---DLKIKNMGSWASLVQK 1208
KPVDV + P K K E + ++ D+++ +
Sbjct: 377 YKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPD 436
Query: 1209 HPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDA 1268
H + A+ D FE R A+ +E E+ + A + A ++ S D+
Sbjct: 437 HEVV--AMARKLQDVFEM--RFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDS 492
Query: 1269 LEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELA 1328
+ + +++ + Q+ + QEQ + +Q AA++ Q Q ++P+ ++E
Sbjct: 493 SSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALS-----QPQQNKPKKKEKDKKE-- 545
Query: 1329 RKREQERRRRE 1339
+K+E+ +R+ E
Sbjct: 546 KKKEKHKRKEE 556
Score = 58.9 bits (141), Expect = 3e-08
Identities = 98/502 (19%), Positives = 168/502 (33%), Gaps = 112/502 (22%)
Query: 884 PARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQ-LQKVQPPT 942
P A +P TQTP PP+ P P ++ L +Q + V PP
Sbjct: 197 PNTTQASTPPQTQTPQPNPPPVQATPH-----------PFPAVTPDLIVQTPVMTVVPPQ 245
Query: 943 PLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPM 1002
PL Q+ PP P P QPPP P PQP Q PP QP+
Sbjct: 246 PL------QTPPPVPPQP------------QPPPAPAPQP-----VQSHPPIIAATPQPV 282
Query: 1003 QFSTHIQQ---PPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHL 1059
+ +++ P P H PP P P K ++ Q S R K
Sbjct: 283 KTKKGVKRKADTTTPTTIDPIHEPPSLPPEP----KTTKLGQRRESSRPVKPPKKDVPDS 338
Query: 1060 REAPSP---------LMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAAS-----VVQPQ 1105
++ P+P L S + + + H + +P E + P
Sbjct: 339 QQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPM 398
Query: 1106 PLVVVKEEKIHSPIIRSEP---------FSPSLRPEPPKHPESIKAP----------VHL 1146
+ +K K+ + R FS + PP H A +
Sbjct: 399 DMSTIK-SKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKM 457
Query: 1147 PQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLV 1206
P PE V V P + PP + PP + D
Sbjct: 458 PDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDS------------------------- 492
Query: 1207 QKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDE 1266
SS + SS+D E+ RA R E +E+ + A + + + + + ++ +
Sbjct: 493 -------SSDSDSSTDDSEE-ERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKK 544
Query: 1267 DALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRE 1326
+ ++ + EE ++ + ++ ++ ++ + + + P S+P + + E
Sbjct: 545 EKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEE 604
Query: 1327 LARKREQERRRREAMAATIDMN 1348
K +R+ ++D+N
Sbjct: 605 DKCKPMSYEEKRQ---LSLDIN 623
Score = 53.9 bits (128), Expect = 1e-06
Identities = 48/168 (28%), Positives = 66/168 (39%), Gaps = 30/168 (17%)
Query: 831 PQPELPPHLPQPPEHSTP---PHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARP 887
PQ + P P PP +TP P + +V P + PQ P +PP+P P
Sbjct: 206 PQTQTPQPNP-PPVQATPHPFPAVTPDLIVQTPVMTVVPPQ----PLQTPPPVPPQPQPP 260
Query: 888 PAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPS 947
PA PA PQP + PP + P P T ++ + PT + P
Sbjct: 261 PA--PA-------PQPVQSHPPIIAAT----PQPVKTKKGVK----RKADTTTPTTIDPI 303
Query: 948 VKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPR 995
PP LPP P + Q ++ P PP+ P QQH P +
Sbjct: 304 -----HEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEK 346
Score = 50.8 bits (120), Expect = 9e-06
Identities = 54/209 (25%), Positives = 82/209 (39%), Gaps = 20/209 (9%)
Query: 675 LRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSK--KKGHPG 732
L+K + E+ +++ +K +G E+ ++ S+ ++ P+++ + P
Sbjct: 158 LQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPP 217
Query: 733 REQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPA 792
+ H PV PP P Q PPP PP QP PPP P P Q
Sbjct: 218 VQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPP----QPQPPPAPAPQPVQ---- 269
Query: 793 MKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPH-----LPQPPEHST 847
S PP AT PV + D T +H P P LPP L Q E S
Sbjct: 270 --SHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEP-PSLPPEPKTTKLGQRRESSR 326
Query: 848 PPHLNQHAVVSPPALHNALPQQPSRPSNR 876
P + V P + + P++ S+ S +
Sbjct: 327 PVKPPKKDV--PDSQQHPAPEKSSKVSEQ 353
Score = 40.8 bits (94), Expect = 0.009
Identities = 76/426 (17%), Positives = 148/426 (34%), Gaps = 88/426 (20%)
Query: 457 MPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQE 516
+P +P+ P P P + A P + +D++T +
Sbjct: 253 VPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTT------------- 299
Query: 517 QLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKN 576
+ +HE + +P+ K ++ + + K K ++V ++++ A E K +++
Sbjct: 300 -IDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPK----KDVPDSQQHPAPEKSSKVSEQL 354
Query: 577 NSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHI 636
+ + + + P Y+ + + Y + + +D++ + + R
Sbjct: 355 KCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRD 414
Query: 637 IQSREPSLK-------NSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVI 689
Q ++ NP + E+ K + E+ R + P + V+
Sbjct: 415 AQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEM--------RFAKMPDEPEEPVV 466
Query: 690 AGSS-------KMKGFSSSESESSSESSSSDS--EDSETEMAP----------------- 723
A SS K+ SS SS SS SDS +DSE E A
Sbjct: 467 AVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLA 526
Query: 724 --------KSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPP--------------- 760
K KKK +E+KK H +++++ ++PPP
Sbjct: 527 ALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKK 586
Query: 761 ---PQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVL---EPQLPG 814
P + PPP + +++ P +Q + + P + V ++ EP L
Sbjct: 587 EPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKN 646
Query: 815 SVFDPI 820
S D I
Sbjct: 647 SNPDEI 652
>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
Length = 726
Score = 751 bits (1939), Expect = 0.0
Identities = 422/742 (56%), Positives = 490/742 (66%), Gaps = 88/742 (11%)
Query: 37 PANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPD 96
PA NPPPPE SNP+KP R+TNQLQY+ VV+KTLWKHQFAWPF QPVDA+KLNLPD
Sbjct: 13 PATPGPVNPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLWKHQFAWPFYQPVDAIKLNLPD 72
Query: 97 YYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKL 156
Y+KIIK PMDMGTIKKRLENNYYW+A EC+QDFNTMFTNCYIYNKP DDIVLMA+ALEK+
Sbjct: 73 YHKIIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKI 132
Query: 157 FLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPP 216
FLQK+ ++P EE E++ KG+GR + G G V +S P T Q PP
Sbjct: 133 FLQKVAQMPQEEVELLPPAPKGKGR-KPAAGAQSAGTQQV--AAVSSVSPATPF-QSVPP 188
Query: 217 PVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIA 276
V TP +I TPV T+ T PVPP PPP P P++
Sbjct: 189 TVSQTP---------VIAATPVPTITAN---VTSVPVPPAAAPPP-----PATPIVPVVP 231
Query: 277 ATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPP---EPKTTKLGQRRES-SRPVKPPK 332
TP PV KKGVKRKADTTTPTT PP +PK K+ RRES RP+KPPK
Sbjct: 232 PTP-PVVKKKGVKRKADTTTPTTSAITASRSESPPPLSDPKQAKVVARRESGGRPIKPPK 290
Query: 333 KDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCD 392
KD+ D + K K+SE L+ C IL+EM +KKHAAYAWPFYKPVD EAL LHDY D
Sbjct: 291 KDLEDGEVPQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHD 350
Query: 393 IIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEM 452
IIKHPMD+ST+K K++ REY DAQ F ADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEM
Sbjct: 351 IIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEM 410
Query: 453 RFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLA 512
RFAKMPDEP V +PA+P P + + S S S SDS + DSEEERA RLA
Sbjct: 411 RFAKMPDEP------VEAPALPAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLA 464
Query: 513 ELQEQLKAVHEQLAALSQPQQNKPKK------KEKDKKEKKKEKHKRKEEVEENKKSK-- 564
ELQEQLKAVHEQLAALSQ NKPKK KEK KK+K+KEK K K + EE KK+K
Sbjct: 465 ELQEQLKAVHEQLAALSQAPVNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVA 524
Query: 565 --AKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDI 622
AK+ KK ++++ + ++ + +Y+SEEE++ PMSY+EKRQLSLDI
Sbjct: 525 PPAKQAQQKKAPAKKANSTTTAGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDI 584
Query: 623 NKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKK-RKP 681
N+LPGEKLGRVVHIIQSREPSL++SNPDEIEIDFETLKP+TLRELERYV SCL+KK RKP
Sbjct: 585 NRLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKP 644
Query: 682 -----------------QAEKVDV---------------------------IAGSSKMKG 697
Q +K ++ G S++
Sbjct: 645 FSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSS 704
Query: 698 FSSSESESSSES-SSSDSEDSE 718
SSSES SSS S SSSDS DSE
Sbjct: 705 SSSSESGSSSSSGSSSDSSDSE 726
Score = 52.8 bits (125), Expect = 2e-06
Identities = 104/522 (19%), Positives = 182/522 (34%), Gaps = 89/522 (17%)
Query: 823 FTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPP 882
F Q + +PQ E+ P P P A Q + AA
Sbjct: 133 FLQKVAQMPQEEVELLPPAPKGKGRKP---------------AAGAQSAGTQQVAAVSSV 177
Query: 883 KPARP-PAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPP 941
PA P +V P ++QTP++ P+ P + P PP + PP
Sbjct: 178 SPATPFQSVPPTVSQTPVIAATPV---PTITANVTSVPVPPAAA--------------PP 220
Query: 942 TPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQP 1001
P P V P +PP P ++ ++++ P + PPP
Sbjct: 221 PPATPIV-------PVVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESPPPLS----- 268
Query: 1002 MQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLRE 1061
P Q + G +P P P++ ++ P+H + HLR
Sbjct: 269 ----------DPKQAKVVARRESGGRPIKP----PKKDLEDGEVPQHAGKKGKLSEHLRY 314
Query: 1062 APSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAAS--VVQPQPLVVVKEEKIHSPI 1119
S L +M + + P + V + EL + P L VK +
Sbjct: 315 CDSILR----EMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREY 370
Query: 1120 IRSEPFSPSLRP--------EPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPP 1171
++ F+ +R PP H E + L EM+ + + P P
Sbjct: 371 PDAQGFAADVRLMFSNCYKYNPPDH-EVVAMARKLQDVFEMRFAKMPDEPVEAPA--LPA 427
Query: 1172 PGAPDKDK-----QKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQ 1226
P AP K + E + + D + + A L ++ A S
Sbjct: 428 PAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQ---AP 484
Query: 1227 FRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQ 1286
+ ++KE++EK K + + EKEK +++ E + + +QA++ A++
Sbjct: 485 VNKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKKANSTT 544
Query: 1287 QQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELA 1328
RQ ++ +Q A A+ + + + P S D++R+L+
Sbjct: 545 TAGRQLKKGGKQ----ASASYDSEEEEEGLPMS-YDEKRQLS 581
Score = 31.2 bits (69), Expect = 7.1
Identities = 40/160 (25%), Positives = 59/160 (36%), Gaps = 16/160 (10%)
Query: 767 PPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQP 826
PP P+ + + P + QQ A A+ S P VP Q P P+ T
Sbjct: 149 PPAPKGKGRKPAAGAQSAGTQQVA-AVSSVSPATPFQSVPPTVSQTPVIAATPVPTITAN 207
Query: 827 ILHLPQPELPPHLPQPPE-------HSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAA 879
+ +P P P P PP TPP + + V P + ++R+ +
Sbjct: 208 VTSVPVP--PAAAPPPPATPIVPVVPPTPPVVKKKGV--KRKADTTTPTTSAITASRSES 263
Query: 880 LPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPP 919
PP A A ++ P +PP+ LED E P
Sbjct: 264 PPPLSDPKQAKVVARRESGGRP----IKPPKKDLEDGEVP 299
Score = 31.2 bits (69), Expect = 7.1
Identities = 14/30 (46%), Positives = 14/30 (46%)
Query: 751 APVPQQPPPPPQQPPPPPPPQQQQQPPPPP 780
A V P PP PPPP P PP PP
Sbjct: 206 ANVTSVPVPPAAAPPPPATPIVPVVPPTPP 235
>gi|164419758 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 731 bits (1886), Expect = 0.0
Identities = 418/771 (54%), Positives = 506/771 (65%), Gaps = 93/771 (12%)
Query: 5 SGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQ 64
+ PG R+R ++ +G E+ M++ A Q PAN PPPPE SNP KP R TNQLQ
Sbjct: 27 AAPGKRIRKPSLLYEGFESPTMASVPA-LQLTPAN-----PPPPEVSNPKKPGRVTNQLQ 80
Query: 65 YLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQE 124
YL +VV+K LWKHQFAWPF+QPVDAVKL LPDY+KIIK PMDMGTIK+RLENNYYW A E
Sbjct: 81 YLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASE 140
Query: 125 CIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGR--- 181
C+QDFNTMFTNCYIYNKP DDIVLMA+ LEK+FLQK+ +P EE E+++ K +
Sbjct: 141 CMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGA 200
Query: 182 ------GRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQ 235
G + P VS+V +T + PP+ P V PHP ++
Sbjct: 201 KLAALQGSVTSAHQVPAVSSVSHTALYTPPPEI------PTTVLNIPHP-------SVIS 247
Query: 236 TPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTT 295
+P++ + PP+ PPA QP+ KKGVKRKADTT
Sbjct: 248 SPLLKSLH----SAGPPLLAVTAAPPA-----------------QPLAKKKGVKRKADTT 286
Query: 296 TPT-TIDPIHEPPSLPP---EPKTTKL-GQRRESSRPVKPPKKDVPDSQQHPAPEKSSKV 350
TPT T P+ PP EPK +L RRES RP+KPP+KD+PDSQQ K K+
Sbjct: 287 TPTPTAILAPGSPASPPGSLEPKAARLPPMRRESGRPIKPPRKDLPDSQQQHQSSKKGKL 346
Query: 351 SEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAR 410
SEQLK C+GILKE+ +KKHAAYAWPFYKPVD ALGLHDY DIIKHPMD+ST+K K+E R
Sbjct: 347 SEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENR 406
Query: 411 EYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSS 470
+YRDAQEF ADVRLMFSNCYKYNPPDH+VVAMARKLQDVFE R+AKMPDEP EP S
Sbjct: 407 DYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVS 466
Query: 471 PAVPPP-TKVVAPPSSSDSSSDSSS------------DSDSSTDDSEEERAQRLAELQEQ 517
A+PP K + SS +SSS+SSS + +S + DSEEERA RLAELQEQ
Sbjct: 467 TAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQ 526
Query: 518 LKAVHEQLAALSQPQQNKPKKKEKDKKEKKK---EKHKRKEEVEENKKS-KAKEPP-PKK 572
L+AVHEQLAALSQ +KPK+K + K++KKK EKH+ + +E+ K +A PP PKK
Sbjct: 527 LRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKK 586
Query: 573 TKKNNSSNSNVSKKEPA---------------PMKSKPP--PT-YESEEEDKCKPMSYEE 614
+KK + S + P+ K+ PP PT Y+SEEE++ +PMSY+E
Sbjct: 587 SKKASGSGGGSAALGPSGFGPSGGSGTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDE 646
Query: 615 KRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSC 674
KRQLSLDINKLPGEKLGRVVHIIQ+REPSL++SNP+EIEIDFETLKPSTLRELERYV SC
Sbjct: 647 KRQLSLDINKLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLSC 706
Query: 675 LRKK-RKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPK 724
LRKK RKP K V G +K + + E + + T+ PK
Sbjct: 707 LRKKPRKPYTIKKPV--GKTKEELALEKKRELEKRLQDVSGQLNSTKKPPK 755
Score = 107 bits (266), Expect = 1e-22
Identities = 114/489 (23%), Positives = 189/489 (38%), Gaps = 50/489 (10%)
Query: 45 PPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQ--FAWPFQQPVDAVKLNLPDYYKIIK 102
P + +K + + QL++ ++ + L K +AWPF +PVDA L L DY+ IIK
Sbjct: 332 PDSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIK 391
Query: 103 TPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKIN 162
PMD+ T+K+++EN Y +AQE D MF+NCY YN P D+V MA L+ +F +
Sbjct: 392 HPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYA 451
Query: 163 ELPTEETE-----IMIVQAKGRGRGRKETGTAKPGV-STVPNTTQASTPPQTQTPQPNPP 216
++P E E + G + E+ + + S+ + + + +
Sbjct: 452 KMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEESESSD 511
Query: 217 PVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHP---- 272
+ H + L + + P+ P + + + +
Sbjct: 512 SEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADE 571
Query: 273 ----PIIAATPQPVKTKK-----------GVKRKADTTTPTTIDPIHEPPSLPPEPKTTK 317
P PQP K+KK G + T P + PP T
Sbjct: 572 DDKGPRAPRPPQPKKSKKASGSGGGSAALGPSGFGPSGGSGTKLPKKATKTAPPALPTGY 631
Query: 318 LGQRRESSRPVKPPKKDVPDSQQHPAP-EKSSKVSEQLKCCSGILKEMFAKKHAAYAWPF 376
+ E SRP+ +K + P EK +V ++ L++ ++ +
Sbjct: 632 DSEEEEESRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQAREPSLRDSNPEE-IEIDFET 690
Query: 377 YKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPD 436
KP + L + + K P TIK + + A E ++
Sbjct: 691 LKPSTLRELERYVLSCLRKKPRKPYTIKKPVGKTKEELALEKKRELE------------- 737
Query: 437 HEVVAMARKLQDVF-EMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSD 495
++LQDV ++ K P + SS +++ A SSSDSSS SSS
Sbjct: 738 -------KRLQDVSGQLNSTKKPPKKANEKTESSSAQQVAVSRLSASSSSSDSSSSSSSS 790
Query: 496 SDSSTDDSE 504
S S T DS+
Sbjct: 791 SSSDTSDSD 799
Score = 37.7 bits (86), Expect = 0.076
Identities = 34/121 (28%), Positives = 44/121 (36%), Gaps = 7/121 (5%)
Query: 875 NRAAALPPKPARPPAV----SPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQL 930
+ A P P P V P++ +PLL A PP +L PPA PL +
Sbjct: 222 SHTALYTPPPEIPTTVLNIPHPSVISSPLLKSLHSAGPP-LLAVTAAPPAQPLAKKKGVK 280
Query: 931 YLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQH 990
P L P + PP L P + + P PP + P QQQH
Sbjct: 281 RKADTTTPTPTAILAPGSP--ASPPGSLEPKAARLPPMRRESGRPIKPPRKDLPDSQQQH 338
Query: 991 Q 991
Q
Sbjct: 339 Q 339
Score = 35.0 bits (79), Expect = 0.49
Identities = 28/124 (22%), Positives = 56/124 (45%), Gaps = 19/124 (15%)
Query: 1213 PSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQA 1272
P AKSSS+S + + EE E+ + + + E+E E E R+ + EQ
Sbjct: 470 PPGLAKSSSESSSEESSSESSSEEEEE--EDEEDEEEEESESSDSEEERAHRLAELQEQL 527
Query: 1273 RRAHEEA------------RRRQEQQQQQRQEQQQQQQQQAA-----AVAAAATPQAQSS 1315
R HE+ R+R++++++++++ ++ + + A A PQ + S
Sbjct: 528 RAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKKS 587
Query: 1316 QPQS 1319
+ S
Sbjct: 588 KKAS 591
Score = 33.9 bits (76), Expect = 1.1
Identities = 26/114 (22%), Positives = 55/114 (48%), Gaps = 17/114 (14%)
Query: 1210 PTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDAL 1269
P S+++SSS+ E ++ E+EE E + + E+E E E R+ +
Sbjct: 471 PGLAKSSSESSSE--ESSSESSSEEEEEED----EEDEEEEESESSDSEEERAHRLAELQ 524
Query: 1270 EQARRAHEE-----------ARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQA 1312
EQ R HE+ +R++E+++++++ + ++ + +A A P+A
Sbjct: 525 EQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRA 578
Score = 33.9 bits (76), Expect = 1.1
Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Query: 697 GFSSSESESSSESSSSD--SEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVP 754
G + S SESSSE SSS+ SE+ E E +++ + ++ H ++Q+ V
Sbjct: 472 GLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVH 531
Query: 755 QQPPPPPQQPPPPPPPQQQQQ 775
+Q Q P P +++++
Sbjct: 532 EQLAALSQGPISKPKRKREKK 552
Score = 32.3 bits (72), Expect = 3.2
Identities = 18/68 (26%), Positives = 31/68 (45%), Gaps = 3/68 (4%)
Query: 692 SSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQ---MQQ 748
SS + S S SE E D E+ E+E + +++ H E ++ H+Q + Q
Sbjct: 480 SSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQ 539
Query: 749 APAPVPQQ 756
P P++
Sbjct: 540 GPISKPKR 547
Score = 32.0 bits (71), Expect = 4.2
Identities = 35/129 (27%), Positives = 46/129 (35%), Gaps = 33/129 (25%)
Query: 1063 PSPLMIHSPQMSQFQSL------THQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIH 1116
P P +I SP + S +PP Q + KK R A P P ++
Sbjct: 241 PHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPLAKKKGVKRKADTTTPTPTAILAPGSPA 300
Query: 1117 SPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPD 1176
SP EP + L PP ES GRP I+PP ++ PD
Sbjct: 301 SPPGSLEPKAARL---PPMRRES------------------GRP-IKPPRKD-----LPD 333
Query: 1177 KDKQKQEPK 1185
+Q Q K
Sbjct: 334 SQQQHQSSK 342
Score = 32.0 bits (71), Expect = 4.2
Identities = 17/45 (37%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
Query: 537 KKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNS 581
K KE+ EKK+E KR ++V + + K+PP K +K SS++
Sbjct: 723 KTKEELALEKKRELEKRLQDV-SGQLNSTKKPPKKANEKTESSSA 766
>gi|4826806 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 731 bits (1886), Expect = 0.0
Identities = 418/771 (54%), Positives = 506/771 (65%), Gaps = 93/771 (12%)
Query: 5 SGPGTRLRNLPVMGDGLETSQMSTTQAQAQPQPANAASTNPPPPETSNPNKPKRQTNQLQ 64
+ PG R+R ++ +G E+ M++ A Q PAN PPPPE SNP KP R TNQLQ
Sbjct: 27 AAPGKRIRKPSLLYEGFESPTMASVPA-LQLTPAN-----PPPPEVSNPKKPGRVTNQLQ 80
Query: 65 YLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQE 124
YL +VV+K LWKHQFAWPF+QPVDAVKL LPDY+KIIK PMDMGTIK+RLENNYYW A E
Sbjct: 81 YLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASE 140
Query: 125 CIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGR--- 181
C+QDFNTMFTNCYIYNKP DDIVLMA+ LEK+FLQK+ +P EE E+++ K +
Sbjct: 141 CMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGA 200
Query: 182 ------GRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQ 235
G + P VS+V +T + PP+ P V PHP ++
Sbjct: 201 KLAALQGSVTSAHQVPAVSSVSHTALYTPPPEI------PTTVLNIPHP-------SVIS 247
Query: 236 TPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTT 295
+P++ + PP+ PPA QP+ KKGVKRKADTT
Sbjct: 248 SPLLKSLH----SAGPPLLAVTAAPPA-----------------QPLAKKKGVKRKADTT 286
Query: 296 TPT-TIDPIHEPPSLPP---EPKTTKL-GQRRESSRPVKPPKKDVPDSQQHPAPEKSSKV 350
TPT T P+ PP EPK +L RRES RP+KPP+KD+PDSQQ K K+
Sbjct: 287 TPTPTAILAPGSPASPPGSLEPKAARLPPMRRESGRPIKPPRKDLPDSQQQHQSSKKGKL 346
Query: 351 SEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAR 410
SEQLK C+GILKE+ +KKHAAYAWPFYKPVD ALGLHDY DIIKHPMD+ST+K K+E R
Sbjct: 347 SEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIKHPMDLSTVKRKMENR 406
Query: 411 EYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSS 470
+YRDAQEF ADVRLMFSNCYKYNPPDH+VVAMARKLQDVFE R+AKMPDEP EP S
Sbjct: 407 DYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYAKMPDEPLEPGPLPVS 466
Query: 471 PAVPPP-TKVVAPPSSSDSSSDSSS------------DSDSSTDDSEEERAQRLAELQEQ 517
A+PP K + SS +SSS+SSS + +S + DSEEERA RLAELQEQ
Sbjct: 467 TAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQ 526
Query: 518 LKAVHEQLAALSQPQQNKPKKKEKDKKEKKK---EKHKRKEEVEENKKS-KAKEPP-PKK 572
L+AVHEQLAALSQ +KPK+K + K++KKK EKH+ + +E+ K +A PP PKK
Sbjct: 527 LRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKK 586
Query: 573 TKKNNSSNSNVSKKEPA---------------PMKSKPP--PT-YESEEEDKCKPMSYEE 614
+KK + S + P+ K+ PP PT Y+SEEE++ +PMSY+E
Sbjct: 587 SKKASGSGGGSAALGPSGFGPSGGSGTKLPKKATKTAPPALPTGYDSEEEEESRPMSYDE 646
Query: 615 KRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSC 674
KRQLSLDINKLPGEKLGRVVHIIQ+REPSL++SNP+EIEIDFETLKPSTLRELERYV SC
Sbjct: 647 KRQLSLDINKLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLSC 706
Query: 675 LRKK-RKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPK 724
LRKK RKP K V G +K + + E + + T+ PK
Sbjct: 707 LRKKPRKPYTIKKPV--GKTKEELALEKKRELEKRLQDVSGQLNSTKKPPK 755
Score = 107 bits (266), Expect = 1e-22
Identities = 114/489 (23%), Positives = 189/489 (38%), Gaps = 50/489 (10%)
Query: 45 PPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQ--FAWPFQQPVDAVKLNLPDYYKIIK 102
P + +K + + QL++ ++ + L K +AWPF +PVDA L L DY+ IIK
Sbjct: 332 PDSQQQHQSSKKGKLSEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDIIK 391
Query: 103 TPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKIN 162
PMD+ T+K+++EN Y +AQE D MF+NCY YN P D+V MA L+ +F +
Sbjct: 392 HPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDVFEFRYA 451
Query: 163 ELPTEETE-----IMIVQAKGRGRGRKETGTAKPGV-STVPNTTQASTPPQTQTPQPNPP 216
++P E E + G + E+ + + S+ + + + +
Sbjct: 452 KMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEESESSD 511
Query: 217 PVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHP---- 272
+ H + L + + P+ P + + + +
Sbjct: 512 SEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADE 571
Query: 273 ----PIIAATPQPVKTKK-----------GVKRKADTTTPTTIDPIHEPPSLPPEPKTTK 317
P PQP K+KK G + T P + PP T
Sbjct: 572 DDKGPRAPRPPQPKKSKKASGSGGGSAALGPSGFGPSGGSGTKLPKKATKTAPPALPTGY 631
Query: 318 LGQRRESSRPVKPPKKDVPDSQQHPAP-EKSSKVSEQLKCCSGILKEMFAKKHAAYAWPF 376
+ E SRP+ +K + P EK +V ++ L++ ++ +
Sbjct: 632 DSEEEEESRPMSYDEKRQLSLDINKLPGEKLGRVVHIIQAREPSLRDSNPEE-IEIDFET 690
Query: 377 YKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPD 436
KP + L + + K P TIK + + A E ++
Sbjct: 691 LKPSTLRELERYVLSCLRKKPRKPYTIKKPVGKTKEELALEKKRELE------------- 737
Query: 437 HEVVAMARKLQDVF-EMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSD 495
++LQDV ++ K P + SS +++ A SSSDSSS SSS
Sbjct: 738 -------KRLQDVSGQLNSTKKPPKKANEKTESSSAQQVAVSRLSASSSSSDSSSSSSSS 790
Query: 496 SDSSTDDSE 504
S S T DS+
Sbjct: 791 SSSDTSDSD 799
Score = 37.7 bits (86), Expect = 0.076
Identities = 34/121 (28%), Positives = 44/121 (36%), Gaps = 7/121 (5%)
Query: 875 NRAAALPPKPARPPAV----SPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQL 930
+ A P P P V P++ +PLL A PP +L PPA PL +
Sbjct: 222 SHTALYTPPPEIPTTVLNIPHPSVISSPLLKSLHSAGPP-LLAVTAAPPAQPLAKKKGVK 280
Query: 931 YLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQH 990
P L P + PP L P + + P PP + P QQQH
Sbjct: 281 RKADTTTPTPTAILAPGSP--ASPPGSLEPKAARLPPMRRESGRPIKPPRKDLPDSQQQH 338
Query: 991 Q 991
Q
Sbjct: 339 Q 339
Score = 35.0 bits (79), Expect = 0.49
Identities = 28/124 (22%), Positives = 56/124 (45%), Gaps = 19/124 (15%)
Query: 1213 PSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQA 1272
P AKSSS+S + + EE E+ + + + E+E E E R+ + EQ
Sbjct: 470 PPGLAKSSSESSSEESSSESSSEEEEE--EDEEDEEEEESESSDSEEERAHRLAELQEQL 527
Query: 1273 RRAHEEA------------RRRQEQQQQQRQEQQQQQQQQAA-----AVAAAATPQAQSS 1315
R HE+ R+R++++++++++ ++ + + A A PQ + S
Sbjct: 528 RAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKKS 587
Query: 1316 QPQS 1319
+ S
Sbjct: 588 KKAS 591
Score = 33.9 bits (76), Expect = 1.1
Identities = 26/114 (22%), Positives = 55/114 (48%), Gaps = 17/114 (14%)
Query: 1210 PTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDAL 1269
P S+++SSS+ E ++ E+EE E + + E+E E E R+ +
Sbjct: 471 PGLAKSSSESSSE--ESSSESSSEEEEEED----EEDEEEEESESSDSEEERAHRLAELQ 524
Query: 1270 EQARRAHEE-----------ARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQA 1312
EQ R HE+ +R++E+++++++ + ++ + +A A P+A
Sbjct: 525 EQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRA 578
Score = 33.9 bits (76), Expect = 1.1
Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Query: 697 GFSSSESESSSESSSSD--SEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVP 754
G + S SESSSE SSS+ SE+ E E +++ + ++ H ++Q+ V
Sbjct: 472 GLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVH 531
Query: 755 QQPPPPPQQPPPPPPPQQQQQ 775
+Q Q P P +++++
Sbjct: 532 EQLAALSQGPISKPKRKREKK 552
Score = 32.3 bits (72), Expect = 3.2
Identities = 18/68 (26%), Positives = 31/68 (45%), Gaps = 3/68 (4%)
Query: 692 SSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQ---MQQ 748
SS + S S SE E D E+ E+E + +++ H E ++ H+Q + Q
Sbjct: 480 SSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQ 539
Query: 749 APAPVPQQ 756
P P++
Sbjct: 540 GPISKPKR 547
Score = 32.0 bits (71), Expect = 4.2
Identities = 35/129 (27%), Positives = 46/129 (35%), Gaps = 33/129 (25%)
Query: 1063 PSPLMIHSPQMSQFQSL------THQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIH 1116
P P +I SP + S +PP Q + KK R A P P ++
Sbjct: 241 PHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPLAKKKGVKRKADTTTPTPTAILAPGSPA 300
Query: 1117 SPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPD 1176
SP EP + L PP ES GRP I+PP ++ PD
Sbjct: 301 SPPGSLEPKAARL---PPMRRES------------------GRP-IKPPRKD-----LPD 333
Query: 1177 KDKQKQEPK 1185
+Q Q K
Sbjct: 334 SQQQHQSSK 342
Score = 32.0 bits (71), Expect = 4.2
Identities = 17/45 (37%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
Query: 537 KKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNS 581
K KE+ EKK+E KR ++V + + K+PP K +K SS++
Sbjct: 723 KTKEELALEKKRELEKRLQDV-SGQLNSTKKPPKKANEKTESSSA 766
>gi|46399200 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 595 bits (1533), Expect = e-169
Identities = 360/763 (47%), Positives = 446/763 (58%), Gaps = 138/763 (18%)
Query: 35 PQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNL 94
P A NPPPPE N K R TNQLQYL +VVLK LWKH F+WPFQ+PVDAVKL L
Sbjct: 4 PSRQTAIIVNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQL 63
Query: 95 PDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALE 154
PDYY IIK PMD+ TIKKRLEN YY A ECI+DFNTMF+NCY+YNKPGDDIVLMA+ALE
Sbjct: 64 PDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALE 123
Query: 155 KLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPN 214
KLF+QK++++P EE + + + R + GT Q N
Sbjct: 124 KLFMQKLSQMPQEEQVVGVKE-------RIKKGT-----------------------QQN 153
Query: 215 PPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPI 274
A P+ T + Q + +V P + +P V +
Sbjct: 154 IAVSSAKEKSSPSATEKVFKQQEIPSVFPKTSI----------------SPLNVVQGASV 197
Query: 275 IAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKP--PK 332
+++ + KGVKRKADTTTP T + P ++ + P+K PK
Sbjct: 198 NSSSQTAAQVTKGVKRKADTTTPAT-SAVKASSEFSPT-----FTEKSVALPPIKENMPK 251
Query: 333 KDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCD 392
+PDSQQ K+ KV+EQL+ CS ILKEM AKKH +YAWPFY PVDV ALGLH+Y D
Sbjct: 252 NVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYD 311
Query: 393 IIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEM 452
++K+PMD+ TIK K++ +EY+DA +F ADVRLMF NCYKYNPPDHEVV MAR LQDVFE
Sbjct: 312 VVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFET 371
Query: 453 RFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLA 512
F+K+P EP E S P T + + ++++++SS+ +SS DDSE+ER +RLA
Sbjct: 372 HFSKIPIEPVE-----SMPLCYIKTD-ITETTGRENTNEASSEGNSS-DDSEDERVKRLA 424
Query: 513 ELQEQLKAVHEQLAALSQ-PQQNKPKKKEKDKKEKKKEK------HKRKEEVEENKKSKA 565
+LQEQLKAVH+QL LSQ P + KKKEK KKEKKKEK + RK + K K+
Sbjct: 425 KLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRLKEKS 484
Query: 566 KEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKL 625
K PKK K+ +SE+ED KPM+Y+EKRQLSL+INKL
Sbjct: 485 KRNQPKKRKQQFIG-------------------LKSEDEDNAKPMNYDEKRQLSLNINKL 525
Query: 626 PGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKK-RKPQAE 684
PG+KLGRVVHIIQSREPSL NSNPDEIEIDFETLK STLRELE+YV++CLRK+ KP A+
Sbjct: 526 PGDKLGRVVHIIQSREPSLSNSNPDEIEIDFETLKASTLRELEKYVSACLRKRPLKPPAK 585
Query: 685 KV--------------------DV---------------------------IAGSSKMKG 697
K+ DV ++ SS
Sbjct: 586 KIMMSKEELHSQKKQELEKRLLDVNNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSS 645
Query: 698 FSSSESESSSESSSSDSEDSETEMAPK---SKKKGHPGREQKK 737
SS SSS+ SSSDS DSE+EM PK K P +E K
Sbjct: 646 SSSESESSSSDLSSSDSSDSESEMFPKFTEVKPNDSPSKENVK 688
Score = 104 bits (259), Expect = 7e-22
Identities = 68/190 (35%), Positives = 101/190 (53%), Gaps = 21/190 (11%)
Query: 1171 PPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRA 1230
P G D + E + PV +KD+KIKN SW SL + P PS KSS + F QFR+A
Sbjct: 777 PSGDSDTTMLESECQAPV--QKDIKIKNADSWKSLGK--PVKPSGVMKSSDELFNQFRKA 832
Query: 1231 AREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQR 1290
A EKE + + + +H E+ + L+ + R+ + L E+ + Q +
Sbjct: 833 AIEKEVKARTQELIRKHLEQNTKELKASQENQRDLGNGLTV------ESFSNKIQNKCSG 886
Query: 1291 QEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQ 1350
+EQ++ QQ A + + L + R+LAR++EQERRRREAM TIDM Q
Sbjct: 887 EEQKEHQQSSEA-----------QDKSKLWLLKDRDLARQKEQERRRREAMVGTIDMTLQ 935
Query: 1351 SDLLSIFEEN 1360
SD++++FE N
Sbjct: 936 SDIMTMFENN 945
>gi|46399198 testis-specific bromodomain protein [Homo sapiens]
Length = 947
Score = 595 bits (1533), Expect = e-169
Identities = 360/763 (47%), Positives = 446/763 (58%), Gaps = 138/763 (18%)
Query: 35 PQPANAASTNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNL 94
P A NPPPPE N K R TNQLQYL +VVLK LWKH F+WPFQ+PVDAVKL L
Sbjct: 4 PSRQTAIIVNPPPPEYINTKKNGRLTNQLQYLQKVVLKDLWKHSFSWPFQRPVDAVKLQL 63
Query: 95 PDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALE 154
PDYY IIK PMD+ TIKKRLEN YY A ECI+DFNTMF+NCY+YNKPGDDIVLMA+ALE
Sbjct: 64 PDYYTIIKNPMDLNTIKKRLENKYYAKASECIEDFNTMFSNCYLYNKPGDDIVLMAQALE 123
Query: 155 KLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPN 214
KLF+QK++++P EE + + + R + GT Q N
Sbjct: 124 KLFMQKLSQMPQEEQVVGVKE-------RIKKGT-----------------------QQN 153
Query: 215 PPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPI 274
A P+ T + Q + +V P + +P V +
Sbjct: 154 IAVSSAKEKSSPSATEKVFKQQEIPSVFPKTSI----------------SPLNVVQGASV 197
Query: 275 IAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKP--PK 332
+++ + KGVKRKADTTTP T + P ++ + P+K PK
Sbjct: 198 NSSSQTAAQVTKGVKRKADTTTPAT-SAVKASSEFSPT-----FTEKSVALPPIKENMPK 251
Query: 333 KDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCD 392
+PDSQQ K+ KV+EQL+ CS ILKEM AKKH +YAWPFY PVDV ALGLH+Y D
Sbjct: 252 NVLPDSQQQYNVVKTVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYD 311
Query: 393 IIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEM 452
++K+PMD+ TIK K++ +EY+DA +F ADVRLMF NCYKYNPPDHEVV MAR LQDVFE
Sbjct: 312 VVKNPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARMLQDVFET 371
Query: 453 RFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLA 512
F+K+P EP E S P T + + ++++++SS+ +SS DDSE+ER +RLA
Sbjct: 372 HFSKIPIEPVE-----SMPLCYIKTD-ITETTGRENTNEASSEGNSS-DDSEDERVKRLA 424
Query: 513 ELQEQLKAVHEQLAALSQ-PQQNKPKKKEKDKKEKKKEK------HKRKEEVEENKKSKA 565
+LQEQLKAVH+QL LSQ P + KKKEK KKEKKKEK + RK + K K+
Sbjct: 425 KLQEQLKAVHQQLQVLSQVPFRKLNKKKEKSKKEKKKEKVNNSNENPRKMCEQMRLKEKS 484
Query: 566 KEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKL 625
K PKK K+ +SE+ED KPM+Y+EKRQLSL+INKL
Sbjct: 485 KRNQPKKRKQQFIG-------------------LKSEDEDNAKPMNYDEKRQLSLNINKL 525
Query: 626 PGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKK-RKPQAE 684
PG+KLGRVVHIIQSREPSL NSNPDEIEIDFETLK STLRELE+YV++CLRK+ KP A+
Sbjct: 526 PGDKLGRVVHIIQSREPSLSNSNPDEIEIDFETLKASTLRELEKYVSACLRKRPLKPPAK 585
Query: 685 KV--------------------DV---------------------------IAGSSKMKG 697
K+ DV ++ SS
Sbjct: 586 KIMMSKEELHSQKKQELEKRLLDVNNQLNSRKRQTKSDKTQPSKAVENVSRLSESSSSSS 645
Query: 698 FSSSESESSSESSSSDSEDSETEMAPK---SKKKGHPGREQKK 737
SS SSS+ SSSDS DSE+EM PK K P +E K
Sbjct: 646 SSSESESSSSDLSSSDSSDSESEMFPKFTEVKPNDSPSKENVK 688
Score = 104 bits (259), Expect = 7e-22
Identities = 68/190 (35%), Positives = 101/190 (53%), Gaps = 21/190 (11%)
Query: 1171 PPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRA 1230
P G D + E + PV +KD+KIKN SW SL + P PS KSS + F QFR+A
Sbjct: 777 PSGDSDTTMLESECQAPV--QKDIKIKNADSWKSLGK--PVKPSGVMKSSDELFNQFRKA 832
Query: 1231 AREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQR 1290
A EKE + + + +H E+ + L+ + R+ + L E+ + Q +
Sbjct: 833 AIEKEVKARTQELIRKHLEQNTKELKASQENQRDLGNGLTV------ESFSNKIQNKCSG 886
Query: 1291 QEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAATIDMNFQ 1350
+EQ++ QQ A + + L + R+LAR++EQERRRREAM TIDM Q
Sbjct: 887 EEQKEHQQSSEA-----------QDKSKLWLLKDRDLARQKEQERRRREAMVGTIDMTLQ 935
Query: 1351 SDLLSIFEEN 1360
SD++++FE N
Sbjct: 936 SDIMTMFENN 945
>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
Length = 1170
Score = 160 bits (404), Expect = 1e-38
Identities = 193/684 (28%), Positives = 255/684 (37%), Gaps = 169/684 (24%)
Query: 704 ESSSESSSSDSEDSETEMAPK-----SKKKGHPGR--------EQKKHHHHHHQQMQQAP 750
E S+E+ ++ E E E K S++ G G +Q++ + P
Sbjct: 247 ELSAEAKAALLEFEERERQHKQGRYSSRRGGRRGGPLMCRGVGDQRRESTERGRMKDHRP 306
Query: 751 APVPQQPPPPPQQPPPPPPPQQQQ------QPPP------------PPPPPSM---PQQA 789
A +P QPP PQ PPPPPPP QQQ QP P P PP M PQ
Sbjct: 307 ALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLE 366
Query: 790 APAMKSSPPPFIATQVPV---LEPQLPGSVFDPIGHFTQPILHLPQPEL-PPHLPQPPEH 845
P M +PPP + Q P + P G+V P+ P+ P+P + P P PPE
Sbjct: 367 TPRMMMTPPP-VTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEF 425
Query: 846 STPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQ--- 902
P H +P + N+ Q P P PP P ++ P P
Sbjct: 426 --PQH-------TPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLF 476
Query: 903 -----PPMAQPPQVLLEDEEP--PAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPP 955
PP PP LL P PL Q Q Q QP P V+ QPP
Sbjct: 477 LEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQ-QGQQPVFPRERPVRPALQPP 535
Query: 956 PP-----------------LPP-------------PPHPSVQQQLQQQPPPPPPPQPQPP 985
P +PP P H Q PP PPP QPQP
Sbjct: 536 GPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQ 595
Query: 986 PQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHS 1045
Q Q QPPP+ QPP QPPH PP Q PPPQ PQ QH H
Sbjct: 596 -QPQQQPPPQ-------------HQPP----HQPPHQPPPQHQPPPQ-HPPQHPPQHQHH 636
Query: 1046 PRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQ----PKKQELR---A 1098
HH HL P PLM S QF+ + PQ + P++Q LR
Sbjct: 637 HHHH--------HLSVPPPPLMPMS--QPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTT 686
Query: 1099 ASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVG 1158
+ V +P+ ++ + +R P +PS E + ++KP+
Sbjct: 687 SQNVSKRPMQQMQPTAPRNSNLRELPIAPS------HVIEMSSSRCSATPSAQVKPIVSA 740
Query: 1159 RPVIRPPEQNAPPPGAPDKDKQKQEPKTPVA-PKKDLKIKNMGSWASLVQKHPTTPSSTA 1217
P P A + K + K +P +PVA PK++ K T
Sbjct: 741 SP---PSRAVAGSRSSQGKTEVKVKPASPVAQPKEEAK--------------------TE 777
Query: 1218 KSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHE 1277
D E+ R R K E +K L+ E K+KE RQ++ +R+ E LE
Sbjct: 778 TEFPDEDEE-TRLYRLKIEEQKRLR---EEILKQKELRRQQQAGARKKE-LLE------- 825
Query: 1278 EARRRQEQQQQQRQEQQQQQQQQA 1301
R Q+QQQ +Q++QA
Sbjct: 826 --RLAQQQQQLYAPPPPAEQEEQA 847
Score = 71.2 bits (173), Expect = 6e-12
Identities = 106/480 (22%), Positives = 165/480 (34%), Gaps = 71/480 (14%)
Query: 739 HHHHHQQMQQAPAPVPQQPPPPPQQPPPP--PPPQQQQQPPPP------------PPPPS 784
H QQ QQ P P Q P PP QPPP PPPQ Q PP PPPP
Sbjct: 590 HQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPL 649
Query: 785 MPQ---QAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFT--QPILHLPQPELPPHL 839
MP Q P ++++ P ++++ PQ G + H T Q + P ++ P
Sbjct: 650 MPMSQPQFRPHVQTAQPQASSSRMQC--PQRQG-----LRHNTTSQNVSKRPMQQMQPTA 702
Query: 840 PQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPL 899
P+ P H + + +A P +P A+ P + S T+ +
Sbjct: 703 PRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASP-PSRAVAGSRSSQGKTEVKV 761
Query: 900 LPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVK---------- 949
P P+AQP + + E P + +L +++ ++++ ++
Sbjct: 762 KPASPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKK 821
Query: 950 ------VQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPR------PV 997
Q Q PPPP +Q L P P P P Q + R V
Sbjct: 822 ELLERLAQQQQQLYAPPPPAEQEEQALSPSPTNGNPLLPFPGAQVRQNVKNRLLVKNQDV 881
Query: 998 HLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTG 1057
+ +Q T P Q GQQ + + + + + HK P
Sbjct: 882 SISNVQPKTSNFVPSSANMQY-----QGQQMKALKHLRQTRTVPQSQTQPLHKVLPIKPA 936
Query: 1058 HLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHS 1117
+ E P + +P+++ Q + P + + P V+ K+
Sbjct: 937 DVEE---PAVPQTPRVASIQGRPQDTKPGVK-RTVTHRTNSGGGDGPHISSKVRVIKLSG 992
Query: 1118 PIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPP--PGAP 1175
S+ F HPE P LPQ PE+ P + + PP P P
Sbjct: 993 GGGESDGFF---------HPEG--QPQRLPQPPEVGPQPARKVTLTRGGLQQPPHLPAGP 1041
Score = 43.9 bits (102), Expect = 0.001
Identities = 44/187 (23%), Positives = 67/187 (35%), Gaps = 31/187 (16%)
Query: 174 VQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLI 233
+ +G G R+E+ P P Q P P PPP Q
Sbjct: 283 LMCRGVGDQRRESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQ-------------- 328
Query: 234 VQTPVMTVVPPQPLQTPPPV-------PPQPQ--PPPAPAPQPVQSHPPIIAATPQPVKT 284
Q P+ ++ PQPLQ PV PPQ PP P+ + + PP+ P+ +
Sbjct: 329 -QQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHI 387
Query: 285 KKGVKRKADTTTPTTIDPI--HEPPSLPPE--PKTTKLGQRRESSRP---VKPPKKDVPD 337
K T + P+ P++ P+ P + Q P +PP+ + D
Sbjct: 388 NPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQD 447
Query: 338 SQQHPAP 344
+ P P
Sbjct: 448 QWRAPPP 454
Score = 40.4 bits (93), Expect = 0.012
Identities = 40/148 (27%), Positives = 50/148 (33%), Gaps = 18/148 (12%)
Query: 195 TVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVP 254
T PN PP QP P Q P P Q P PP Q PP P
Sbjct: 574 TQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPP---QHPPQHP 630
Query: 255 PQ------------PQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDP 302
PQ P PP P QP Q P + A PQ ++ ++ TT
Sbjct: 631 PQHQHHHHHHHLSVPPPPLMPMSQP-QFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQN 689
Query: 303 IHEPPSLPPEPKTTKLGQRRESSRPVKP 330
+ + P +P + RE P+ P
Sbjct: 690 VSKRPMQQMQPTAPRNSNLRE--LPIAP 715
Score = 40.0 bits (92), Expect = 0.015
Identities = 117/616 (18%), Positives = 195/616 (31%), Gaps = 134/616 (21%)
Query: 206 PQTQTPQPNPPPVQ----ATPHPFPAVTPDLIVQTPVMTVVPP----QPLQTPPPVPPQP 257
P + T +P PP Q PF +Q P+ +PP QP Q PPQ
Sbjct: 546 PGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQH 605
Query: 258 QPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTK 317
QPP P QP H P P PP PP+ +
Sbjct: 606 QPPHQPPHQPPPQHQP----------------------------PPQHPPQHPPQHQHHH 637
Query: 318 LGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKC--CSGILKEMFAKKHAAYAWP 375
P P P + H + S +++C G+ ++ +
Sbjct: 638 HHHHLSVPPPPLMPMSQ-PQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQ 696
Query: 376 FYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPP 435
+P L + H ++MS+ + A V+ + S P
Sbjct: 697 QMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATP---------SAQVKPIVS-----ASP 742
Query: 436 DHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSD 495
VA +R Q E++ V P + V P + + ++
Sbjct: 743 PSRAVAGSRSSQGKTEVK-------------------VKPASPVAQPKEEAKTETE---- 779
Query: 496 SDSSTDDSEEERAQRL-AELQEQLKAVHEQLAALSQPQQNKPKKKEKDKK--EKKKEKHK 552
D+ EE R RL E Q++L+ + L + QQ +KKE ++ +++++ +
Sbjct: 780 ---FPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQLYA 836
Query: 553 RKEEVEENKKSKAKEPP--------PKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEE 604
E+ +++ + P P + N N + K + + + P T S
Sbjct: 837 PPPPAEQEEQALSPSPTNGNPLLPFPGAQVRQNVKNRLLVKNQDVSISNVQPKT--SNFV 894
Query: 605 DKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTL 664
M Y+ G+++ + H+ Q+R + P + +KP+ +
Sbjct: 895 PSSANMQYQ-------------GQQMKALKHLRQTRTVPQSQTQPLHKVL---PIKPADV 938
Query: 665 RELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPK 724
E PQ +V I G + + + +S +
Sbjct: 939 EE-----------PAVPQTPRVASIQGRPQDTKPGVKRTVTHRTNSGGGDGPHISSKVRV 987
Query: 725 SKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQ-----QQQPPPP 779
K G G H P PQ+ P PP+ P P QQPP
Sbjct: 988 IKLSGGGGESDGFFH----------PEGQPQRLPQPPEVGPQPARKVTLTRGGLQQPPHL 1037
Query: 780 PPPPSMPQQAAPAMKS 795
P P P +KS
Sbjct: 1038 PAGPHAHSPVPPGIKS 1053
Score = 36.6 bits (83), Expect = 0.17
Identities = 119/645 (18%), Positives = 212/645 (32%), Gaps = 124/645 (19%)
Query: 528 LSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKE 587
L P Q +P++ ++ + + H+ + + + PP + + + +
Sbjct: 586 LPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVP 645
Query: 588 PAPMKSKPPPTYE----------SEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHII 637
P P+ P + S +C S +++K P +
Sbjct: 646 PPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRP----------M 695
Query: 638 QSREPSL-KNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMK 696
Q +P+ +NSN E+ I PS + E+ S R P A+ +++ S +
Sbjct: 696 QQMQPTAPRNSNLRELPI-----APSHVIEM-----SSSRCSATPSAQVKPIVSASPPSR 745
Query: 697 GFSSSESE----------SSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQM 746
+ S S +S + + +ETE P ++ R + + +++
Sbjct: 746 AVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEF-PDEDEETRLYRLKIEEQKRLREEI 804
Query: 747 QQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVP 806
+ QQ ++ QQQQQ PPPP +QA ++ P + P
Sbjct: 805 LKQKELRRQQQAGARKKELLERLAQQQQQLYAPPPPAEQEEQALSPSPTNGNPLL----P 860
Query: 807 VLEPQLPGSVFDPIGHFTQPI-LHLPQPELPPHLP-------QPPEHSTPPHLNQHAVVS 858
Q+ +V + + Q + + QP+ +P Q + HL Q V
Sbjct: 861 FPGAQVRQNVKNRLLVKNQDVSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTV- 919
Query: 859 PPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEP 918
PQ ++P ++ LP KPA + P +PQ P Q +D +P
Sbjct: 920 --------PQSQTQPLHK--VLPIKPAD--------VEEPAVPQTPRVASIQGRPQDTKP 961
Query: 919 PAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPP 978
+ + + ++ + P P Q+ P PP
Sbjct: 962 GVKRTVTHRTNSGGGDGPHISSKVRVIKLSGGGGESDGFFHPEGQP-------QRLPQPP 1014
Query: 979 PPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQ 1038
PQ P R V L QQPPH P G P P +
Sbjct: 1015 EVGPQ---------PARKVTLTRGGL------------QQPPHLPAGPHAHSPVPPGIKS 1053
Query: 1039 VIQHH-------HSPRHHKSDPYSTGHLRE----------APSPLMIHSPQMS------Q 1075
+ H H + P G L P P ++ +S Q
Sbjct: 1054 IQGIHPAKKAIMHGRGRGVAGPMGRGRLMPNKQNLRVVECKPQPCVVSVEGLSSSTTDAQ 1113
Query: 1076 FQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPII 1120
+SL P Q++Q Q+ +A + + + ++K H +I
Sbjct: 1114 LKSLLMSVGPIQSLQMLPQQRKAIAKFKEPAHALAFQQKFHRHMI 1158
Score = 32.7 bits (73), Expect = 2.4
Identities = 41/163 (25%), Positives = 58/163 (35%), Gaps = 29/163 (17%)
Query: 196 VPNTTQASTPPQTQTPQ--PNPPPV-QATPHPFP---AVTPDLIVQTPVMTVVPPQP--- 246
VP S P PQ P PP Q TP P P + P L +Q PPQ
Sbjct: 401 VPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDP 460
Query: 247 ----------------LQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKR 290
L+ P PP P P + PV + P+ P P ++G +
Sbjct: 461 FFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQP 520
Query: 291 KADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKK 333
P + P +PP ++ G ++RP PP++
Sbjct: 521 VFPRERP--VRPALQPPGPVGILHFSQPGS--ATTRPFIPPRQ 559
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 150 bits (379), Expect = 8e-36
Identities = 184/686 (26%), Positives = 254/686 (37%), Gaps = 152/686 (22%)
Query: 692 SSKMKGFSSSES---ESSSESSSSDSEDSETEMA-------------PKSKKKGHPGREQ 735
SS +K SSS S S+ S+ SDS S+T+ A ++ K+G E
Sbjct: 531 SSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEES 590
Query: 736 KKHH----HHHHQQMQQAPAPVPQ----------QPPPPPQQPPPPPPPQQQQQPPPPPP 781
K + + + +P P+ PP PP PPPPPPP PPPPPP
Sbjct: 591 SKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPP-----PPPPPP 645
Query: 782 PPSMPQQAAPAMKSSPPPFIA-TQVPVLE--PQLPGSVFDP------IGHFTQPILHLPQ 832
PP +P Q+AP+ S+ P F+ + + L+ Q G++F P +P + +P
Sbjct: 646 PPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPP 705
Query: 833 PELPPHLPQPPEHSTP-------------PHLNQHAVVSPPA-------LHNALPQQPSR 872
+ P P PP TP P L Q + PP + P P
Sbjct: 706 NGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPP 765
Query: 873 PSNRAAALPPK-PARPPAVSPALTQT-PLLPQPPMAQPPQVLLEDEEPPAPPLTSMQM-- 928
P A LPP+ P +P PA T T + P A PP PP PP
Sbjct: 766 PPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPP-----TPTPPVPPAKKQPAFP 820
Query: 929 QLYLQQLQKVQP---PTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPP----- 980
Y+ P P P LP + PPP P P PSV +Q+ Q PPPP P
Sbjct: 821 ASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMES 880
Query: 981 QP-QPPPQQQHQPPPRPVHLQPMQFSTHIQ------QPPPPQGQ---QPPHPPPGQQPPP 1030
QP +P P P V +P + I PPPP+ PP P P PPP
Sbjct: 881 QPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPP 940
Query: 1031 PQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHS-----------PQMSQFQSL 1079
P P SP S S G + P+P S P+ SL
Sbjct: 941 PPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSL 1000
Query: 1080 THQ-SPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIH------------------SPII 1120
+ +PP ++ P K+ L P P K K++ +P++
Sbjct: 1001 VSKFTPPAESGSPSKETL-------PPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVL 1053
Query: 1121 RSE--------PFSPSLRPEPPKHPESIKAPVHLPQRP-EMKPVDVGRPVIRPPEQNAPP 1171
P PS PP PE+ LP P E+ V G + N P
Sbjct: 1054 SGRGKDSVVEFPSPPSDSDFPPPPPET-----ELPLPPIEIPAVFSGNTSPKVAVVN-PQ 1107
Query: 1172 PGAPDKDKQKQEPKTPVAPKKD-------LKIKNMGSWASLVQKHPTTPSSTAKSSSDSF 1224
P K K+ P P PK++ +I + A++V + PT+P S+
Sbjct: 1108 PQQWSKMSVKKAP-PPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFL 1166
Query: 1225 EQFRRAAREKE-EREKALKAQAEHAE 1249
R + K R +L ++ AE
Sbjct: 1167 ADLNRTLQRKSITRHGSLSSRMSRAE 1192
Score = 72.0 bits (175), Expect = 4e-12
Identities = 94/348 (27%), Positives = 121/348 (34%), Gaps = 119/348 (34%)
Query: 745 QMQQAPAPVPQQPPPPPQQPP--PPPPPQQQQQPPPPPPPPSMP---QQAAPAMKSS--- 796
Q P P P PPPPP+ PPPPP PPPPPPP + P + +P K+S
Sbjct: 905 QPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTS 964
Query: 797 ------PPPFIATQVPVL--------EPQLPGSVFDPIGHFTQPILH-------LPQPEL 835
PPP + EP+ P SV + FT P LP P
Sbjct: 965 SPGGKKPPPTPQRNSSIKSSSGAEHPEPKRP-SVDSLVSKFTPPAESGSPSKETLPPPAA 1023
Query: 836 PP-------------------------------------HLPQPPEHST-PPHLNQHAVV 857
PP P PP S PP + +
Sbjct: 1024 PPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELP 1083
Query: 858 SPP---------------ALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQ 902
PP A+ N PQQ S+ S + A P +P R S LTQ + Q
Sbjct: 1084 LPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRND--STRLTQAEISEQ 1141
Query: 903 PPMAQP-PQVLLEDEEPPAPPLTSMQMQL-YLQQLQKVQPPTPL-----LPSVKVQSQPP 955
P MA PQV P P +S+ +Q +L L + + L S +++P
Sbjct: 1142 PTMATVVPQV-------PTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPT 1194
Query: 956 PP-----LPPPP---------------HPSVQQQLQQQPPPPPPPQPQ 983
LPPPP H S L++ PPP PP + Q
Sbjct: 1195 ATMDDMALPPPPPELLSDQQKAGYGGSHISGYATLRRGPPPAPPKRDQ 1242
Score = 64.3 bits (155), Expect = 8e-10
Identities = 151/776 (19%), Positives = 237/776 (30%), Gaps = 145/776 (18%)
Query: 208 TQTPQPNPPPVQATPHPFPAVTPDLIVQ----TPVMTVVPPQPLQTPPPVPPQPQPPPAP 263
TQ + + +++ P+ ++ P L Q TP P PL PPP PP P PPP P
Sbjct: 585 TQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPP 644
Query: 264 APQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRE 323
P P+ S A + P+ K + + + + +PP+ P + +
Sbjct: 645 PPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHS-GALFKPPTPPV--------MQSQ 695
Query: 324 SSRP--VKPPKKDVPDSQQHPAPEKSSKVSEQLK--CCSGILKEMFAK---------KHA 370
S +P + PP VP P P QLK C+ L + A +H
Sbjct: 696 SVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHI 755
Query: 371 AYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCY 430
P P + P + TI + + A
Sbjct: 756 TQVAP---PTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAA---------- 802
Query: 431 KYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSS 490
PP K Q F + +P P P V V P +P A P S S
Sbjct: 803 ---PPTPTPPVPPAKKQPAFPASY--IPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSP 857
Query: 491 DSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEK 550
S + ++ Q A SQP + P K K
Sbjct: 858 VPSV----------------VKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAK 901
Query: 551 HKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPM 610
K + PPP+ +S P P PPP S DK
Sbjct: 902 PKWQPSSIPVPSPDFPPPPPE-----SSLVFPPPPPSPVPAPPPPPPPTASPTPDK---- 952
Query: 611 SYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERY 670
+ PG+K + K S+P + P T +
Sbjct: 953 ------------SGSPGKK-------------TSKTSSPGGKK------PPPTPQRNSSI 981
Query: 671 VTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMA----PKSK 726
+S + +P+ VD + S S S+ + ++ + + ++ P
Sbjct: 982 KSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVL 1041
Query: 727 KKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMP 786
++G + + + P+P P PPPPP+ + PP P
Sbjct: 1042 QQGCVSAKAPVLSGRGKDSVVEFPSP-------PSDSDFPPPPPETELPLPPIEIPAVFS 1094
Query: 787 QQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHS 846
+P +V V+ PQ Q + + PP P P+ +
Sbjct: 1095 GNTSP------------KVAVVNPQ------------PQQWSKMSVKKAPP--PTRPKRN 1128
Query: 847 TPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPA--RPPAVSPALTQTPLLPQPP 904
L Q + P + +PQ P+ P + + P A ++T+ L
Sbjct: 1129 DSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRM 1188
Query: 905 MAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPP 960
P ++D P PP + Q QK + + PPP PP
Sbjct: 1189 SRAEPTATMDDMALPPPPPELLSDQ------QKAGYGGSHISGYATLRRGPPPAPP 1238
Score = 59.3 bits (142), Expect = 2e-08
Identities = 50/194 (25%), Positives = 65/194 (33%), Gaps = 25/194 (12%)
Query: 185 ETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTP------- 237
++ + KP + PN PP P P Q P P P P
Sbjct: 693 QSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQV 752
Query: 238 --VMTVVPPQPLQTPPPVPPQPQPPPA--------PAPQPVQSHPPIIAATPQPVKTKKG 287
+ V PP P PPP P P PP A PAP ++ P++ P T
Sbjct: 753 QHITQVAPPTP--PPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPV 810
Query: 288 VKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPD------SQQH 341
K P + P P P P T Q+ ++P P VP SQ
Sbjct: 811 PPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFP 870
Query: 342 PAPEKSSKVSEQLK 355
P P + S+ LK
Sbjct: 871 PPPTPPAMESQPLK 884
Score = 58.5 bits (140), Expect = 4e-08
Identities = 46/151 (30%), Positives = 58/151 (38%), Gaps = 6/151 (3%)
Query: 204 TPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAP 263
TPP ++ P P P PAV Q P VP PPP PPP P
Sbjct: 874 TPPAMESQPLKPVPANVAPQSPPAVKAKPKWQ-PSSIPVPSPDFPPPPPESSLVFPPPPP 932
Query: 264 APQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRE 323
+P P PP A+P P K+ K+ + T++P +PP P + K E
Sbjct: 933 SPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGG----KKPPPTPQRNSSIKSSSGAE 988
Query: 324 SSRPVKPPKKDVPDSQQHPAPEKSSKVSEQL 354
P K P D S+ P E S E L
Sbjct: 989 HPEP-KRPSVDSLVSKFTPPAESGSPSKETL 1018
Score = 52.4 bits (124), Expect = 3e-06
Identities = 55/192 (28%), Positives = 69/192 (35%), Gaps = 48/192 (25%)
Query: 193 VSTVPNTTQASTP-PQTQTPQPNPPPVQATPHPF---PAVTPDLIVQTPVMTVVPPQPLQ 248
+ V + TQ + P P P P P P QA P P PA T V V PP P
Sbjct: 749 IHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTP 808
Query: 249 TPPP-----------VPPQPQPPPAPAP-------------------QPVQSHPPIIAAT 278
PP +PP P PP P P PV S IA+
Sbjct: 809 PVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQ 868
Query: 279 PQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDS 338
P T ++ + P + P PP++ +PK + SS PV P D P
Sbjct: 869 FPPPPTPPAMESQPLKPVPANVAP-QSPPAVKAKPKW------QPSSIPV--PSPDFP-- 917
Query: 339 QQHPAPEKSSKV 350
P P +SS V
Sbjct: 918 ---PPPPESSLV 926
Score = 52.0 bits (123), Expect = 4e-06
Identities = 50/168 (29%), Positives = 63/168 (37%), Gaps = 11/168 (6%)
Query: 186 TGTAKPGVS-TVPNTTQASTPP---QTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTV 241
T T P V+ P T PP Q P PP TP P P P L Q
Sbjct: 791 TKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTP-PVPVPPPTLPKQQSFCAK 849
Query: 242 VPPQPLQTPPPVPPQ--PQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTT 299
PP PL P V Q Q PP P P ++S P + P V + KA +
Sbjct: 850 PPPSPLSPVPSVVKQIASQFPPPPTPPAMESQP--LKPVPANVAPQSPPAVKAKPKWQPS 907
Query: 300 IDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKS 347
P+ P PP P+++ + S PP P + P P+KS
Sbjct: 908 SIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTAS--PTPDKS 953
Score = 37.0 bits (84), Expect = 0.13
Identities = 36/147 (24%), Positives = 51/147 (34%), Gaps = 34/147 (23%)
Query: 196 VPNTTQASTPPQTQTP---QPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPP 252
VP +PP + QP+ PV + P P L+ P PP P+ PPP
Sbjct: 886 VPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPP-----PPSPVPAPPP 940
Query: 253 VP---PQPQPPPAPAP--------QPVQSHPPIIAATPQPVKTKKGV-----KRKADTTT 296
P P P + +P P PP +K+ G KR + +
Sbjct: 941 PPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSL 1000
Query: 297 PTTIDPIHE----------PPSLPPEP 313
+ P E PP+ PP+P
Sbjct: 1001 VSKFTPPAESGSPSKETLPPPAAPPKP 1027
Score = 34.3 bits (77), Expect = 0.84
Identities = 48/204 (23%), Positives = 72/204 (35%), Gaps = 66/204 (32%)
Query: 177 KGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQT----PQPNPPPVQA-----TPH---- 223
K G+K + T+ PG P T Q ++ ++ + P+P P V + TP
Sbjct: 952 KSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESG 1011
Query: 224 -------PFPAVTPD-------------------LIVQTPVM------TVV----PPQPL 247
P PA P + + PV+ +VV PP
Sbjct: 1012 SPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDS 1071
Query: 248 QTPPPVPPQPQPPPAPAPQPV----QSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPI 303
PPP PP+ + P P P + P + PQP + K +KA
Sbjct: 1072 DFPPP-PPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKA----------- 1119
Query: 304 HEPPSLPPEPKTTKLGQRRESSRP 327
PP+ P +T+L Q S +P
Sbjct: 1120 -PPPTRPKRNDSTRLTQAEISEQP 1142
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 149 bits (376), Expect = 2e-35
Identities = 258/1251 (20%), Positives = 464/1251 (37%), Gaps = 208/1251 (16%)
Query: 45 PPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQ-PVDAVKL----NLPDYYK 99
PPPP+ P +PK+ + +R+ + K Q P + P+ ++ +P K
Sbjct: 9834 PPPPKV--PEEPKKVFEEK---IRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRK 9888
Query: 100 IIKTPMDMGTIKKRLENNYYWNAQECI---QDFNTMFTNCYIYNKPGDDIVLMAEALEKL 156
+ P+ + + K LE +E + +++ YI+ ++ + E + +
Sbjct: 9889 EVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHE---EEEFITEEEVVPV 9945
Query: 157 FLQKINELPT----EETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQ 212
K+ E+P EE + + V K KE AK V VP + P P+
Sbjct: 9946 IPVKVPEVPRKPVPEEKKPVPVPKK------KEAPPAK--VPEVPKKPEEKVP--VLIPK 9995
Query: 213 PNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPP-VPPQPQPP------PAPAP 265
PP P P+ V PV P+ ++ PP VP P+ P P PAP
Sbjct: 9996 KEKPPPAKVPEVPKKPVPEEKVPVPV-----PKKVEAPPAKVPEVPKKPVPEKKVPVPAP 10050
Query: 266 QPVQSHPPIIAATPQPV----KTKKGVKRKADT---TTPTTIDPIHEPPSLPPEPKTTKL 318
+ V++ P + P+ + K V +K + P +P+ P +LP E +
Sbjct: 10051 KKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVL-F 10109
Query: 319 GQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYK 378
+ V P +++V ++ PE+ + E+ +E+ ++ Y
Sbjct: 10110 EEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEE--------EEIPPEEEEVPPEEEYV 10161
Query: 379 PVDVEALGLHDYCDIIKH----PMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNP 434
P + E + + +K P + IK K+ ++
Sbjct: 10162 PEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKK----------------------- 10198
Query: 435 PDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSS 494
+ K ++ + ++P + EE + + P +V P S +
Sbjct: 10199 ------VVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIP 10252
Query: 495 DSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRK 554
+ S ++ EE R+ E+ + KAV E + PKK E + K+ + K
Sbjct: 10253 EEPPSIEEVEEVAPPRVPEVIK--KAVPEAPTPV-------PKKVEAPPAKVSKKIPEEK 10303
Query: 555 EEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEE 614
V KK P+ KK V KKE + PP + E+K +E
Sbjct: 10304 VPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKE-----AVPPAKGRTVLEEKVSVAFRQE 10358
Query: 615 ---KRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEID--FETLKPSTLRELER 669
K +L L++ + E++ P+E E E + E+E
Sbjct: 10359 VVVKERLELEVVEAEVEEI------------------PEEEEFHEVEEYFEEGEFHEVEE 10400
Query: 670 YVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKS-KKK 728
++ L + R + +V+ + ++ E ++ E SE + PK K
Sbjct: 10401 FIK--LEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTK 10458
Query: 729 GHPGRE-QKKHHHHHHQQMQQAPAPVPQQPPPPPQQPP---PP---------PPPQQQQQ 775
P +E K + + + VP++P PP + P PP P P ++
Sbjct: 10459 VVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKP 10518
Query: 776 PPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLE-PQLPGSVFDPIGHFTQPILHLPQPE 834
PPP P P++ P K PP +VP + P++P + + P P+PE
Sbjct: 10519 EAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAA---VPEKKVPEAIPPKPE 10575
Query: 835 L-PPHLPQPPEH--------STPPHLNQHAVVSPPALHNAL----------PQQPSRPSN 875
PP +P+ P+ + PP + V P + P++P P
Sbjct: 10576 SPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPT 10635
Query: 876 RA--------------AALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAP 921
+ A+PPKP PP P + + P + + +PP ++E+ EP AP
Sbjct: 10636 KVPEVPKVAVPEKKVPEAIPPKPESPP---PEVFEEP--EEVALEEPPAEVVEEPEPAAP 10690
Query: 922 PLTSM--QMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPP 979
P ++ + + ++ V P LP VKV P +P P V + + PP P
Sbjct: 10691 PQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVP 10750
Query: 980 PQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQV 1039
P+ ++ P+ + P + ++P + P P + PPP +P+++
Sbjct: 10751 EVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEI 10810
Query: 1040 I-QHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLT-----HQSPPQQNVQPKK 1093
+ +P K P + E P P + P+ + ++PP + +P+K
Sbjct: 10811 APEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEK 10870
Query: 1094 Q-ELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIK-APVHLP---- 1147
E P P +E + I + + PE P+ PE ++ P+ +P
Sbjct: 10871 VIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEK 10930
Query: 1148 --------QRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAP 1190
++PE K V + V+R + P P K ++ ++P P P
Sbjct: 10931 KVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPP 10981
Score = 143 bits (361), Expect = 1e-33
Identities = 248/1168 (21%), Positives = 430/1168 (36%), Gaps = 172/1168 (14%)
Query: 228 VTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQ----PVQSHPPIIAAT--PQP 281
V P + V+ P + P + P PVP + + PPA P+ P + P +I P P
Sbjct: 9942 VVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPP 10001
Query: 282 VKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKP-PKKDVPDSQQ 340
K + K+ P+ E P PK + + P KP P+K VP
Sbjct: 10002 AKVPEVPKK-----------PVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPV--- 10047
Query: 341 HPAPEK----SSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKH 396
PAP+K +KV E + K++ ++ P K V+ + + +
Sbjct: 10048 -PAPKKVEAPPAKVPE-------VPKKLIPEEKKPTPVP--KKVEAPPPKVPKKREPVPV 10097
Query: 397 PMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKL---QDVFEMR 453
P+ + + L E +E + + + P + EV+ ++ ++
Sbjct: 10098 PVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPE 10157
Query: 454 FAKMPDE----PEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQ 509
+P+E PEE V+ P VP P V ++ ++E A
Sbjct: 10158 EEYVPEEEEFVPEEEVLPEVKPKVPVPAPV---------PEIKKKVTEKKVVIPKKEEAP 10208
Query: 510 RLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPP 569
A++ E K V E+ L + ++ P + ++ +E+ + + EE ++ + PP
Sbjct: 10209 P-AKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPP 10267
Query: 570 --PKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPG 627
P+ KK + P P K + PP S++ EEK + + + P
Sbjct: 10268 RVPEVIKK-----AVPEAPTPVPKKVEAPPAKVSKKIP-------EEKVPVPVQKKEAPP 10315
Query: 628 EKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVD 687
K+ V + P K P + E + P+ R + S ++ E+++
Sbjct: 10316 AKVPEV----PKKVPEKKVLVPKK-----EAVPPAKGRTVLEEKVSVAFRQEVVVKERLE 10366
Query: 688 VIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQ 747
+ ++++ E E + E E E K ++ R +++H ++
Sbjct: 10367 LEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQH----RVEEEHRVEKVHRVI 10422
Query: 748 QAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPV 807
+ + P+ PP P ++ PP PP +P++ PA P I + V
Sbjct: 10423 EVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKV 10482
Query: 808 LEPQLPG-------SVFDP---IGHFTQPILHLPQPELPP-HLPQPPEHSTPPHLNQHAV 856
P+ P V P + P+ +PE PP +P+ P+ P + V
Sbjct: 10483 RVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVP----EKKV 10538
Query: 857 VSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDE 916
PP P++P P + +P V A+ P P P + + P+ ++ ++
Sbjct: 10539 PVPP------PKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEK 10592
Query: 917 EPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPP-----PPLPPPPHPSVQQQLQ 971
+ PA P ++ ++ + P ++P KV PP PP P P V +
Sbjct: 10593 KVPAAPPKKPEVT----PVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEK 10648
Query: 972 QQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPP 1031
+ P PP PPP+ +P + P + + PPQ PP P ++ P
Sbjct: 10649 KVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPA 10708
Query: 1032 QPAK-----PQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQ 1086
AK P +V + K P EAP P + P +
Sbjct: 10709 VVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAP-PAKVPEVPKEVVPEKKVAVPKK 10767
Query: 1087 QNVQPKK-QELRAASVVQPQPLVVVKEE-KIHSPIIRSEPFSPSLRPEPPKHPESIK-AP 1143
V P K E+ V++ +P V V E + P + EP + PE PE K P
Sbjct: 10768 PEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEP--EEIAPEEEIAPEEEKPVP 10825
Query: 1144 VHLPQRPEMKPVDVGR-----------PVIRPPEQNAPPPGAPDKDKQKQEPK------- 1185
V + PE+ P V PVI+ PE APPP P+ +K ++PK
Sbjct: 10826 VAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPE--APPPKEPEPEKVIEKPKLKPRPPP 10883
Query: 1186 -TPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQ 1244
P PK+D+K K A +K P P + E+ + +
Sbjct: 10884 PPPAPPKEDVKEKIFQLKAIPKKKVPEKP-------------------QVPEKVELTPLK 10924
Query: 1245 AEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAV 1304
EK+ +L ER ++E L+ R E +E+ + + ++ V
Sbjct: 10925 VPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPE------------EEEPKVEPKKLEKV 10972
Query: 1305 AAAATPQAQSSQPQSMLDQQRELARKRE 1332
A P+ +P ++ R+R+
Sbjct: 10973 KKPAVPEPPPPKPVEEVEVPTVTKRERK 11000
Score = 139 bits (351), Expect = 1e-32
Identities = 265/1262 (20%), Positives = 452/1262 (35%), Gaps = 250/1262 (19%)
Query: 205 PPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQP---PP 261
PP+ P P + P P P V PP P P VP +P P P
Sbjct: 9285 PPKVPELPEKPAPEEVAPVPIP------------KKVEPPAP--KVPEVPKKPVPEEKKP 9330
Query: 262 APAPQPVQSHPPIIAATP-QPVKTKK---GVKRKADTTTPTTIDPIHEPPSLPPEPKTTK 317
P P+ + PP + P +PV +K V +K + P + + + + E K T
Sbjct: 9331 VPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKE-APPAKVPEVQK--GVVTEEKITI 9387
Query: 318 LGQRRESSRPVKP--PKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWP 375
+ QR ES P P PKK VP+ ++ P P K +V K + K+ ++ A P
Sbjct: 9388 VTQREESPPPAVPEIPKKKVPE-ERKPVPRKEEEVPPPPK-VPALPKKPVPEEKVAVPVP 9445
Query: 376 FYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPP 435
K K P + + K E R F A+ +L F+ +
Sbjct: 9446 VAK----------------KAPPPRAEVSKKTVVEEKR----FVAEEKLSFAVPQRVEVT 9485
Query: 436 DHEVVA-----MARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSS 490
HEV A + + + V + + E EE + P + V S
Sbjct: 9486 RHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISK 9545
Query: 491 DSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEK 550
++ T ER ++ L+ ++ A E+ P+ PKK +KK
Sbjct: 9546 RVEAEPAEVT-----ERQEKKIVLKPKIPAKIEEPPPAKVPE--APKKIVPEKK------ 9592
Query: 551 HKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCK-- 608
V K K PPPK ++ K+P P K PP + EE K
Sbjct: 9593 ------VPAPVPKKEKVPPPKVPEE---------PKKPVPEKKVPPKVIKMEEPLPAKVT 9637
Query: 609 --PMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDE----IEIDFETLKPS 662
M ++ ++ + + K RV EP K + P+E ++ E P+
Sbjct: 9638 ERHMQITQEEKVLVAVTKKEAPPKARV-----PEEP--KRAVPEEKVLKLKPKREEEPPA 9690
Query: 663 TLRELERYV-----TSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDS 717
+ E + V S KR+PQ K +V K + ++ E S + E
Sbjct: 9691 KVTEFRKRVVKEEKVSIEAPKREPQPIK-EVTIMEEKERAYTLEEEAVSVQREEEYEEYE 9749
Query: 718 E------TEMAPKSKKKGHPGREQKKH--HHHHHQQMQQAPAPVPQQP---PPPPQQPPP 766
E E P + + E++++ + H + + + P+P +P P P +P
Sbjct: 9750 EYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKA 9809
Query: 767 PPP-------PQQQQQPPPP----PPPPSMPQQ---------------------AAPAMK 794
PP P+++ P P PPPP +P++ PA K
Sbjct: 9810 PPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAK 9869
Query: 795 ------------SSPPPFIATQVPVLEPQLPGSVF-DPIGHFTQPILHLPQ--------- 832
P P PV P++P + + + + + H+ +
Sbjct: 9870 VPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEY 9929
Query: 833 --------------PELPPHLPQPPEHSTPPHLNQHAV----VSPPALHNALPQQPSRPS 874
P +P +P+ P P V +PPA +P+ P +P
Sbjct: 9930 IHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPA---KVPEVPKKPE 9986
Query: 875 NRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQ 934
+ L PK +PP PA + P +P+ P+ + + ++ APP ++
Sbjct: 9987 EKVPVLIPKKEKPP---PA--KVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVP 10041
Query: 935 LQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPP 994
+KV P P K PP +P P + ++ + P P P P ++ +P P
Sbjct: 10042 EKKVPVPAP-----KKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVP 10096
Query: 995 RPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPY 1054
PV L + ++ P + P + P + + + + P + P
Sbjct: 10097 VPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPP 10156
Query: 1055 STGHLRE----APSPLMIHS-----PQMSQFQSLTHQSPPQQNVQPKKQELRAASV---- 1101
++ E P ++ P + + + ++ V PKK+E A V
Sbjct: 10157 EEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVP 10216
Query: 1102 --VQPQPLVVVKEEKIHSPIIRSEPFSPSLRPE----------------PPKHPESIK-- 1141
V+ + +++ KEE++ + EP + E PP+ PE IK
Sbjct: 10217 KKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKA 10276
Query: 1142 ---APVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKN 1198
AP +P++ E P V + + PE+ P P + K+ K P PKK + K
Sbjct: 10277 VPEAPTPVPKKVEAPPAKVSKKI---PEEKVP---VPVQKKEAPPAKVPEVPKKVPEKK- 10329
Query: 1199 MGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQE 1258
LV K P AK + E+ A R++ ++ L+ + AE E+ +E
Sbjct: 10330 -----VLVPKKEAVP--PAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEE 10382
Query: 1259 RMRSRE--DEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQ 1316
E +E + + + R E++ + + + + +A V P+A
Sbjct: 10383 FHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKG 10442
Query: 1317 PQ 1318
P+
Sbjct: 10443 PE 10444
Score = 135 bits (341), Expect = 2e-31
Identities = 239/1133 (21%), Positives = 407/1133 (35%), Gaps = 183/1133 (16%)
Query: 190 KPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQT 249
KP + VP + P + + P P P V+A P P V + + V P +
Sbjct: 9998 KPPPAKVPEVPKKPVPEE-KVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAP 10056
Query: 250 PPPVPPQP------QPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPI 303
P VP P + P P P+ V++ PP + +PV + ++ + I P
Sbjct: 10057 PAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVP- 10115
Query: 304 HEPPSLPPE----PKTTKLGQRRESSRP----VKPPKKDVPDSQQHPAPEKSSKVSEQLK 355
E LP E P+ ++ E P + P +++VP +++ PE+ V E+
Sbjct: 10116 -EEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEY-VPEEEEFVPEE-- 10171
Query: 356 CCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREY--- 412
+L E+ K P K E + + P + + K+E +
Sbjct: 10172 ---EVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAP-PAKVPEVPKKVEEKRIILP 10227
Query: 413 RDAQEFGADVRLMFSNCYKYNPPDHEVVA---MARKLQDVFEMRFAKMPDEPEEPVVAVS 469
++ + +V P+ E ++ + + + E+ P PE AV
Sbjct: 10228 KEEEVLPVEVT---------EEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVP 10278
Query: 470 SPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALS 529
P P KV APP+ S + +++ A++ E K V E+ +
Sbjct: 10279 EAPTPVPKKVEAPPAKV-----SKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVP 10333
Query: 530 QPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPA 589
+ + P K +EK +++ V+E + + E ++ + + E
Sbjct: 10334 KKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEG 10393
Query: 590 PMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSRE------PS 643
+E EE K + EE+ ++ EK+ RV+ + ++ E P
Sbjct: 10394 EF-------HEVEEFIKLEQHRVEEEHRV---------EKVHRVIEVFEAEEVEVFEKPK 10437
Query: 644 LKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSES 703
P+ E KP T + V + P+ K V+ ++
Sbjct: 10438 APPKGPEISEKIIPPKKPPT-----KVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPP 10492
Query: 704 ESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQ 763
E E ++ KK + ++ P P P++P PP +
Sbjct: 10493 TKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTK 10552
Query: 764 PPPPPPPQQQQQ------PP----PPPPPPSMPQQAAPAMK-SSPPPFIATQVPVLEPQL 812
P P ++ PP PPP P P++ P K + PP PV P+
Sbjct: 10553 VPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEA 10612
Query: 813 PGSVFDPIGHFTQPILHLPQPELPP-HLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPS 871
P V + P+ +PE+PP +P+ P+ + P A+ PP + P+
Sbjct: 10613 PKEV---VPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAI--PPKPESPPPEVFE 10667
Query: 872 RPSNRAAALPPKPA---RPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQM 928
P A PP PA P +T P P P P V + E PP +
Sbjct: 10668 EPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKE 10727
Query: 929 QLYLQQLQKVQPPTPLLPSVKVQSQPP-------------PPLPPPPHPSVQQQ--LQQQ 973
+ +++ V P P P KV P P +PP P V ++ L+++
Sbjct: 10728 VVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEK 10787
Query: 974 PPPPPPPQPQPPPQQQHQPP----------PRPVHLQPMQFSTHIQQPPP---------- 1013
P P P + + PP + ++ P P P+ + PPP
Sbjct: 10788 PAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKII 10847
Query: 1014 -----PQGQQPPHPPPGQ--------------QPPPPQPAKPQQVIQHH----------- 1043
P ++P PPP + +PPPP PA P++ ++
Sbjct: 10848 PEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKK 10907
Query: 1044 -----HSPRHHKSDPYST-GHLREAPSPLMIHSPQMSQ---FQSLTHQSPPQQN--VQPK 1092
P + P G ++ L P+ + +S+ + P ++ V+PK
Sbjct: 10908 VPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPK 10967
Query: 1093 KQE-LRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLP-QRP 1150
K E ++ +V +P P V+E ++ + R PEP K PE IK + LP P
Sbjct: 10968 KLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKI-----PEPTKVPE-IKPAIPLPAPEP 11021
Query: 1151 EMKPVDVGRPVIRPPEQNAPPP-GAP------DKDKQKQEPKTPVA-PKKDLK 1195
+ KP + + PP + P P AP K + + PK A PK +K
Sbjct: 11022 KPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIK 11074
Score = 130 bits (326), Expect = 1e-29
Identities = 236/1160 (20%), Positives = 419/1160 (36%), Gaps = 252/1160 (21%)
Query: 142 PGDDIVLMAEAL--EKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNT 199
P ++ VL E + E+ L + E+ EE E++ E P +P
Sbjct: 10102 PQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVL-----------PEEEEVLPEEEEIPPE 10150
Query: 200 TQASTPPQTQTPQPNP--PPVQATPH-----PFPAVTPDLIVQTPVMTVVPPQPLQTP-- 250
+ P + P+ P + P P PA P++ + VV P+ + P
Sbjct: 10151 EEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPA 10210
Query: 251 --PPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHE--P 306
P VP + + P+ + P + P+ ++ + + P +I+ + E P
Sbjct: 10211 KVPEVPKKVEEKRIILPKEEEVLPVEVTEEPE----EEPISEEEIPEEPPSIEEVEEVAP 10266
Query: 307 PSLP------------PEPKTTKLGQRRESSR------PVKPPKKDVPDSQQHPAPEKSS 348
P +P P PK + + S + PV KK+ P ++ PE
Sbjct: 10267 PRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAK---VPEVPK 10323
Query: 349 KVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKL- 407
KV E+ K + KK A ++ + ++K +++ +++++
Sbjct: 10324 KVPEK--------KVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVE 10375
Query: 408 ---EAREYRDAQEFGADVRL----MFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDE 460
E E+ + +E+ + F ++ + V ++ +VFE ++ ++
Sbjct: 10376 EIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEK 10435
Query: 461 PEEPVVA--VSSPAVP---PPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQ 515
P+ P +S +P PPTKVV +E ++ E+
Sbjct: 10436 PKAPPKGPEISEKIIPPKKPPTKVV----------------------PRKEPPAKVPEVP 10473
Query: 516 EQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKK 575
+++ V E++ +P+ P K + K+ ++K V KK +A PPPK +
Sbjct: 10474 KKI-VVEEKVRVPEEPR--VPPTKVPEVLPPKEVVPEKKVPVPPAKKPEA--PPPKVPEA 10528
Query: 576 NNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVH 635
P P K + PPT E P EK+
Sbjct: 10529 PKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVP----EKK------------------- 10565
Query: 636 IIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKM 695
+ P S P E+ P +E+ +KP+ V V
Sbjct: 10566 -VPEAIPPKPESPPPEV--------PEAPKEVVPEKKVPAAPPKKPEVTPVKV------- 10609
Query: 696 KGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQ 755
E+ + + + P K + P + + ++ VP+
Sbjct: 10610 -----------PEAPKEVVPEKKVPVPPPKKPEVPPTKVPEV------PKVAVPEKKVPE 10652
Query: 756 QPPPPPQQPPPP--PPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLP 813
PP P+ PPP P++ PP P+ AAP + PP + PV E + P
Sbjct: 10653 AIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPP-----KKPVPEKKAP 10707
Query: 814 GSVFDPIGHFTQPILHLPQPELPP-HLPQPPEHSTP----PHLNQHAVVSPPALHNALPQ 868
V +PELPP +P+ P+ P P + +PPA +P+
Sbjct: 10708 AVV-------------AKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPK 10754
Query: 869 QPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQM 928
+ + A+P KP PPA P + + P+L + P P E E P P +
Sbjct: 10755 EV--VPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVP----ERAESPPPEV----- 10803
Query: 929 QLYLQQLQKVQPPTPLLPS----VKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQP 984
++ +++ P + P V V + P +PPP P ++P P + P
Sbjct: 10804 ---YEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVP-------EEPKKIIPEKKVP 10853
Query: 985 PPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHH 1044
++ PPP+ +P P + + P P +PPPP PA P++ ++
Sbjct: 10854 VIKKPEAPPPK--------------EPEPEKVIEKPKLKP--RPPPPPPAPPKEDVKE-- 10895
Query: 1045 SPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQP 1104
L+ P + PQ+ + LT P + +K+ + +P
Sbjct: 10896 ----------KIFQLKAIPKKKVPEKPQVPEKVELT----PLKVPGGEKKVRKLLPERKP 10941
Query: 1105 QPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPV-DVGRPVIR 1163
+P KEE + ++R P + E PK E +K P +P+ P KPV +V P +
Sbjct: 10942 EP----KEEVVLKSVLRKRPEEEEPKVE-PKKLEKVKKPA-VPEPPPPKPVEEVEVPTVT 10995
Query: 1164 PPEQNAP-PPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSD 1222
E+ P P P+ P PK + ++K ++ P P T ++
Sbjct: 10996 KRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKT-------IKPPPVEPEPTPIAAPV 11048
Query: 1223 SFEQFRRAAREKEEREKALK 1242
+ + A K +E+A K
Sbjct: 11049 TVPVVGKKAEAKAPKEEAAK 11068
Score = 112 bits (281), Expect = 2e-24
Identities = 268/1321 (20%), Positives = 472/1321 (35%), Gaps = 261/1321 (19%)
Query: 226 PAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVK-T 284
P PD V P M + P + PP V P P P P P + PP P+ ++ T
Sbjct: 8934 PPDIPDSRVPIPTMPIRAVPPEEIPPVVAP---PIPLLLPTPEEKKPP-----PKRIEVT 8985
Query: 285 KKGVKRKAD--TTTPTTIDPIHEPPSLPPEPKT---------TKLGQRRESSRPVKPPKK 333
KK VK+ A P + P E PP P T + + E + + +K
Sbjct: 8986 KKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPEIIDVSSKAEEVKIMTITRK 9045
Query: 334 DVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHA-AYAWPFYKPVDVEALGLHDYCD 392
++ EK V ++ + +E + + Y PF +P E DY +
Sbjct: 9046 KEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEP--DEDYEE 9103
Query: 393 I---IKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDV 449
I K + + E +EY + +E + + Y+ + EV+ + +++ +
Sbjct: 9104 IKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAYQ----EREVIQVQKEVYEE 9159
Query: 450 FEMRF--AKMPDEP--------EEPVV-------------AVSSPAVPPPTKVVAP---- 482
R AK+P++ ++PV+ V VP +K + P
Sbjct: 9160 SHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPS 9219
Query: 483 -------------PSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQL---KAVHEQLA 526
P+ S + +EEE + + E+Q+++ + +H ++
Sbjct: 9220 RTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAIS 9279
Query: 527 ALSQPQQNKPKKKEKDKKEK---------------------KKEKHKRKEEVEENKKSKA 565
+P P+ EK E+ KK + K+ V KK A
Sbjct: 9280 KRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPA 9339
Query: 566 KEPP----PKKTKKNNSSNSNVSKKEPAP-----------------------MKSKPP-- 596
P PKK V+KK+ AP +S PP
Sbjct: 9340 APPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAV 9399
Query: 597 ---PTYESEEEDKCKPMSYEE----KRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNP 649
P + EE K P EE + +L +P EK+ V P K + P
Sbjct: 9400 PEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPV-------PVAKKAPP 9452
Query: 650 DEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSES 709
E+ T+ E +R+V PQ +V S++ + S E E S S
Sbjct: 9453 PRAEV-----SKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSIS 9507
Query: 710 SSSDSEDSETEMAPKSKKKGHPGREQ---KKHHHHHHQQMQQAPAPVPQ----------- 755
+ E E E A ++ + E+ ++ H ++++ PA V +
Sbjct: 9508 VYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPK 9567
Query: 756 -----QPPPPPQQPPPP---------PPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFI 801
+ PPP + P P P P +++ PPP P P++ P K P
Sbjct: 9568 IPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPP---- 9623
Query: 802 ATQVPVLEPQLPGSVFDPIGHFTQP---ILHLPQPELPP--HLPQPPEHSTPPH----LN 852
+V +E LP V + TQ ++ + + E PP +P+ P+ + P L
Sbjct: 9624 --KVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLK 9681
Query: 853 QHAVVSPPALHNALPQ---QPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPP 909
PPA + + + S A P+P + + + L + ++
Sbjct: 9682 PKREEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQR 9741
Query: 910 QVLLE----------------DEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQ 953
+ E +E + + Y + + + P +P V +
Sbjct: 9742 EEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEE 9801
Query: 954 PPPPLP-PPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPP 1012
P P P PP +++ + ++ P P P+ PP + P+ V + ++ S ++
Sbjct: 9802 PVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKE 9861
Query: 1013 PPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQ 1072
+P P KP++V+ P K + + E P L P+
Sbjct: 9862 QV-----------TEPAAKVPMKPKRVVAEEKVPVPRK-EVAPPVRVPEVPKEL---EPE 9906
Query: 1073 MSQFQS--LTH-----QSPPQQNVQPKKQELRAASVVQPQPLVV-------VKEEKIHSP 1118
F+ +TH ++ + +++ + VV P+ V V EEK P
Sbjct: 9907 EVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVP 9966
Query: 1119 IIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGR-----------PVIRPPEQ 1167
+ + + P+ PE PK PE K PV +P++ + P V PV P +
Sbjct: 9967 VPKKKEAPPAKVPEVPKKPEE-KVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKV 10025
Query: 1168 NAPPPGAPDKDKQK-QEPKTPV-APKK----DLKIKNMGSWASLVQKHPTTPSSTAKSSS 1221
APP P+ K+ E K PV APKK K+ + +K PT ++
Sbjct: 10026 EAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPP 10085
Query: 1222 DSFEQFRR-----AAREKEER---EKALKAQAEHAEKEKERLRQERMRSREDEDAL-EQA 1272
+ R A +EE E+ + + E +E+E L +E E+E+ L E+
Sbjct: 10086 PKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEE 10145
Query: 1273 RRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKRE 1332
EE E++ +E+ +++ V A + + + +++ + K+E
Sbjct: 10146 EIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKE 10205
Query: 1333 Q 1333
+
Sbjct: 10206 E 10206
Score = 103 bits (256), Expect = 1e-21
Identities = 219/1134 (19%), Positives = 376/1134 (33%), Gaps = 271/1134 (23%)
Query: 202 ASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPP 261
A P + + P P P P P VPP+ ++ P+P +
Sbjct: 9595 APVPKKEKVPPPKVPEEPKKPVP--------------EKKVPPKVIKMEEPLPAKVTERH 9640
Query: 262 APAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQR 321
Q Q ++A T + K V EP PE K KL +
Sbjct: 9641 M---QITQEEKVLVAVTKKEAPPKARVP--------------EEPKRAVPEEKVLKLKPK 9683
Query: 322 RESSRP----------VKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAA 371
RE P VK K + ++ P P K + E+ + + +E
Sbjct: 9684 REEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEE-------- 9735
Query: 372 YAWPFYKPVDVEALGLHDYCDIIKH-PMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCY 430
A + + E +DY + ++ P + + E REY +E
Sbjct: 9736 -AVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEE------------- 9781
Query: 431 KYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSS 490
HE + EPE+P+ P P PTK APP+
Sbjct: 9782 ------HE-----------------EYITEPEKPIPVKPVPEEPVPTKPKAPPA------ 9812
Query: 491 DSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEK 550
+ KAV E+ + P++ KP + ++ KK +
Sbjct: 9813 ------------------------KVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFE 9848
Query: 551 HKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPM 610
K + + + +K + EP K K +K P P K PP E + +P
Sbjct: 9849 EKIRISITKREKEQVTEPAAKVPMK--PKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPE 9906
Query: 611 SYEEKRQLSLDINKLPGEKLGRVVH-------------IIQSREPSLKNSNPDEIEIDFE 657
+ ++ + + E+ +H +I + P + E +
Sbjct: 9907 EVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVP 9966
Query: 658 TLK---------PSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSE 708
K P ++ E V + KK KP KV + E
Sbjct: 9967 VPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVP--------KKPVPEEKVP 10018
Query: 709 SSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPP-PPQQPPPP 767
++ P+ KK P +KK ++++ PA VP+ P P++ P
Sbjct: 10019 VPVPKKVEAPPAKVPEVPKKPVP---EKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPT 10075
Query: 768 PPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPI 827
P P++ + PPP P P A+ ++ E LP + + + +
Sbjct: 10076 PVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEE--EEVLPEEEEV 10133
Query: 828 LHLPQPELPPHLPQPPEHSTPPHLNQHA------VVSPPALHNALPQQP---------SR 872
L + LP PPE P ++ V L P+ P +
Sbjct: 10134 LPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKK 10193
Query: 873 PSNRAAALPPKPARPPAVSPALTQTP-----LLPQPPMAQPPQVLLEDEEPPAPPLTSMQ 927
+ + +P K PPA P + + +LP+ P +V E EE P +
Sbjct: 10194 VTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPE 10253
Query: 928 MQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPP-----PHPSVQQQLQQQPPP------ 976
++++++V PP +P V ++ P P P P P V +++ ++ P
Sbjct: 10254 EPPSIEEVEEVAPPR--VPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKK 10311
Query: 977 --PPPPQPQPP----------PQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPP 1024
PP P+ P P+++ PP + + + S +Q + +
Sbjct: 10312 EAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVE 10371
Query: 1025 GQQPPPPQPAKPQQVIQHHHSPRHHKSDPY---STGHLREAPSPLMIH-------SPQMS 1074
+ P+ + +V ++ H+ + + + E +H + ++
Sbjct: 10372 AEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVE 10431
Query: 1075 QFQSLTHQSPP------QQNVQPKKQELRAASVVQPQ------PLVVVKEEKIHSPIIRS 1122
F+ ++PP ++ + PKK + +P P +V EEK+ P
Sbjct: 10432 VFEK--PKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVP---E 10486
Query: 1123 EPFSP-----------------------SLRPE--PPKHPES-------IKAPVHLPQRP 1150
EP P + +PE PPK PE+ K PV P++P
Sbjct: 10487 EPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKP 10546
Query: 1151 EMKPVDVGR-----------PVIRPPEQNAPPPGAPDKDKQ-KQEPKTPVAPKK 1192
E+ P V P PP+ +PPP P+ K+ E K P AP K
Sbjct: 10547 EVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPK 10600
Score = 102 bits (253), Expect = 3e-21
Identities = 181/875 (20%), Positives = 333/875 (38%), Gaps = 153/875 (17%)
Query: 545 EKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYE---- 600
E+KK KR E ++ K AK+ K K + + KK P P P E
Sbjct: 8973 EEKKPPPKRIEVTKKAVKKDAKKVVAKP--KEMTPREEIVKKPPPPTTLIPAKAPEIIDV 9030
Query: 601 SEEEDKCKPMSYEEKRQLSLDINKLPGEKLG----RVVHIIQSREPSLKNSNPDEIEIDF 656
S + ++ K M+ K+++ + + +K + V I EP DE+E++
Sbjct: 9031 SSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPY------DELEVE- 9083
Query: 657 ETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSED 716
P T + Y ++ E++ V A + + E + D
Sbjct: 9084 ----PYTEPFEQPYY-----EEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYD 9134
Query: 717 SETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQ---- 772
E ++ ++ + QK+ + H++ + PA VP++ PPP + P ++
Sbjct: 9135 EGEEEWEEAYQEREVIQVQKEVYEESHER--KVPAKVPEKKAPPPPKVIKKPVIEKIEKT 9192
Query: 773 ----------------------QQQPPPPPPPPSMPQQAAPAMK------SSPPPFIAT- 803
Q+P P + + PA+ S F A+
Sbjct: 9193 SRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASH 9252
Query: 804 ---QVPVLEPQLPGSVFDPIGHFTQPILHLP---QPELPPHLPQPPEHSTPPHLNQHAV- 856
+V V P++ + T+ +H+ + E PP +P+ PE P + +
Sbjct: 9253 TEEEVSVTVPEVQKEIV------TEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIP 9306
Query: 857 --VSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLE 914
V PPA +P+ P +P P P + PA P + + P P P P V +
Sbjct: 9307 KKVEPPA--PKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKK 9364
Query: 915 DEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQP 974
E PPA + ++QK + V + + PPP P + P
Sbjct: 9365 KEAPPAK----------VPEVQKGVVTEEKITIVTQREESPPPAVP-----------EIP 9403
Query: 975 PPPPPPQPQPPPQQQHQ-PPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQP 1033
P + +P P+++ + PPP V P ++P P + P P + PPP
Sbjct: 9404 KKKVPEERKPVPRKEEEVPPPPKVPALP-------KKPVPEEKVAVPVPVAKKAPPPRAE 9456
Query: 1034 AKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNV---- 1089
+ V++ K P + + ++S + ++ S ++ V
Sbjct: 9457 VSKKTVVEEKRFVAEEKLS-------FAVPQRVEVTRHEVSAEEEWSY-SEEEEGVSISV 9508
Query: 1090 --QPKKQELRAASV----VQPQPLVVVKEEKIH--SPIIRSEPFSPSLRPE-----PPKH 1136
+ +++E A V V +P V EEK+H S + +EP + R E PK
Sbjct: 9509 YREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKI 9568
Query: 1137 PESIK--APVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDK----QKQEPKTPVAP 1190
P I+ P +P+ P+ + P P ++ PPP P++ K +K+ P +
Sbjct: 9569 PAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKM 9628
Query: 1191 KKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSF---EQFRRAAREKEEREKALKAQAEH 1247
++ L K + Q+ + T K + E+ +RA E EK LK + +
Sbjct: 9629 EEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPE----EKVLKLKPKR 9684
Query: 1248 AEKEKERLRQERMR-SREDEDALEQARRAHE---EARRRQEQQQQQRQEQQQ---QQQQQ 1300
E+ ++ + R R +E++ ++E +R + E +E+++ E++ Q++++
Sbjct: 9685 EEEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEE 9744
Query: 1301 AAAVAAAATPQAQSSQPQSMLDQQRELARKREQER 1335
+ + +P DQ E +RE ER
Sbjct: 9745 YEEYEEYDYKEFEEYEPTEEYDQYEEY-EEREYER 9778
Score = 78.2 bits (191), Expect = 5e-14
Identities = 128/615 (20%), Positives = 224/615 (36%), Gaps = 135/615 (21%)
Query: 456 KMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQ 515
++P+ P+E V PA PP V P ++ + + ++ +
Sbjct: 10580 EVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPE 10639
Query: 516 EQLKAVHE-QLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKE--PPPKK 572
AV E ++ P+ P + ++ E+ + E VEE + + + PPKK
Sbjct: 10640 VPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKK 10699
Query: 573 TKKNNSSNSNVSKKEPAPMKSKP--PPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKL 630
KK PA + KP PP E + P ++++ L + K P
Sbjct: 10700 PVP--------EKKAPAVVAKKPELPPVKVPEVPKEVVP-----EKKVPLVVPKKPEAPP 10746
Query: 631 GRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIA 690
+V + + P K + P + E+ P+ + E+ +KP E+ +
Sbjct: 10747 AKVPEVPKEVVPEKKVAVPKKPEV-----PPAKVPEV----------PKKPVLEEKPAVP 10791
Query: 691 GSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKH------HHHHHQ 744
+ +ES + E E+AP+ +K E++ +
Sbjct: 10792 VPER------AESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKK 10845
Query: 745 QMQQAPAPVPQQP-PPPPQQPPPPPPPQQQQ-QPPPPPPPPSMPQQ----------AAPA 792
+ + PV ++P PPP++P P ++ + +P PPPPPP+ P++ A P
Sbjct: 10846 IIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPK 10905
Query: 793 MKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLN 852
K P + +V + ++PG + + L LP P+P E
Sbjct: 10906 KKVPEKPQVPEKVELTPLKVPGG--------EKKVRKL----LPERKPEPKEE------- 10946
Query: 853 QHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVL 912
VV L RP + PK + P +P+PP +P
Sbjct: 10947 ---VVLKSVLR-------KRPEEEEPKVEPKKLEK-------VKKPAVPEPPPPKPV--- 10986
Query: 913 LEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLP-PPPHPSVQQQLQ 971
EE P +T + +K+ PT +P +K P PLP P P P + +++
Sbjct: 10987 ---EEVEVPTVTKRE--------RKIPEPTK-VPEIK----PAIPLPAPEPKPKPEAEVK 11030
Query: 972 QQPPPPPPPQPQP-----------------PPQQQHQPPPRPVHLQPMQFSTHIQQP--- 1011
PPP P+P P P+++ P P+ P + + I+
Sbjct: 11031 TIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRK 11090
Query: 1012 --PPPQGQQPPHPPP 1024
P G++PP P
Sbjct: 11091 LRPGSGGEKPPDEAP 11105
Score = 72.8 bits (177), Expect = 2e-12
Identities = 169/779 (21%), Positives = 277/779 (35%), Gaps = 169/779 (21%)
Query: 205 PPQTQTPQPNPPP----------------VQATPHPFPAVTPDLIVQTPVMTVVPPQPLQ 248
PP P+ PP V P P P+++ P VVP + +
Sbjct: 10455 PPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVL---PPKEVVPEKKVP 10511
Query: 249 TPPPVPPQPQPPPAP-APQPVQSHPPIIAATPQ-----PVKTKKGVKRKA-DTTTPTTID 301
PP P+ PP P AP+ V + P+ P K + K + P I
Sbjct: 10512 VPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIP 10571
Query: 302 PIHE--PPSLPPEPKTTKLGQRRESSRPVKPPKKD------VPDSQQHPAPEKSSKVSEQ 353
P E PP +P PK E P PPKK VP++ + PEK V
Sbjct: 10572 PKPESPPPEVPEAPKEVV----PEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPP 10627
Query: 354 LKC------CSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKL 407
K + K +K A P KP ++ + P +++ +
Sbjct: 10628 KKPEVPPTKVPEVPKVAVPEKKVPEAIP-PKPESPPP-------EVFEEPEEVALEEPPA 10679
Query: 408 EAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVA 467
E E E A ++ K P+ + A+ K E+ K+P+ P+E V
Sbjct: 10680 EVVE---EPEPAAPPQVTVPP--KKPVPEKKAPAVVAKKP---ELPPVKVPEVPKEVVPE 10731
Query: 468 VSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAA 527
P V P K APP+ ++ E+ +++ +++A
Sbjct: 10732 KKVPLVVPK-KPEAPPA-------------------------KVPEVPKEV-VPEKKVAV 10764
Query: 528 LSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKE 587
+P+ K E KK +EK V E +A+ PPP+ ++ ++E
Sbjct: 10765 PKKPEVPPAKVPEVPKKPVLEEKPA--VPVPE----RAESPPPEVYEEPEEI---APEEE 10815
Query: 588 PAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSRE-PSLKN 646
AP + KP P E EE + P EE +++ +P +K V +I+ E P K
Sbjct: 10816 IAPEEEKPVPVAEEEEPEVPPPAVPEEPKKI------IPEKK----VPVIKKPEAPPPKE 10865
Query: 647 SNPDEIEIDFETLKP-----------STLRELERYVTSCLRKK--RKPQA-EKVDVIAGS 692
P+++ I+ LKP ++E + + +KK KPQ EKV++
Sbjct: 10866 PEPEKV-IEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTP-- 10922
Query: 693 SKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAP 752
K+ G + E E E+ KS + P E+ K +++++ P
Sbjct: 10923 LKVPGGEKKVRKLLPERKPEPKE----EVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVP 10978
Query: 753 VPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQL 812
P P P + P ++++ P P P P PA + P P +V ++P
Sbjct: 10979 EPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKP--EAEVKTIKP-- 11034
Query: 813 PGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTP---PHLNQHAVVSPPALHNALPQQ 869
PP P+P + P P + + A P A P+
Sbjct: 11035 -----------------------PPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKG 11071
Query: 870 PSRPSNRAAALPPKPAR-----------PPAVSPALTQTPLLPQPPMAQPPQVLLEDEE 917
P + + P + R PP +P Q +P + + ++L + E
Sbjct: 11072 PIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESE 11130
Score = 41.2 bits (95), Expect = 0.007
Identities = 45/187 (24%), Positives = 66/187 (35%), Gaps = 23/187 (12%)
Query: 154 EKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPG-VSTVPNTTQASTPPQTQTPQ 212
EK + + E E E +++++ R R +E +P + V PP +
Sbjct: 10929 EKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEE 10988
Query: 213 PNPPPV----QATPHP--FPAVTPDLIVQTPVMTVVPPQPLQT--PPPVPPQPQPPPAPA 264
P V + P P P + P + + P P ++T PPPV P+P P AP
Sbjct: 10989 VEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPV 11048
Query: 265 PQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRES 324
PV A + KG PI P P P + + R
Sbjct: 11049 TVPVVGKKAEAKAPKEEAAKPKG--------------PIKGVPKKTPSPIEAERRKLRPG 11094
Query: 325 SRPVKPP 331
S KPP
Sbjct: 11095 SGGEKPP 11101
Score = 38.5 bits (88), Expect = 0.044
Identities = 58/282 (20%), Positives = 109/282 (38%), Gaps = 29/282 (10%)
Query: 1077 QSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKH 1136
Q L H++PP+ +PK + S+ L ++ SPI S +R P
Sbjct: 247 QQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLA---RQQSPSPIRHSPSPVRHVRAPTPSP 303
Query: 1137 PESIK-------APVHLPQRPEMKPVDVGRPVIRPPEQNAPPP----GAPDKDKQKQEPK 1185
S+ +P+ + P + V PE PPP G + + +
Sbjct: 304 VRSVSPAARISTSPIRSVRSPLLMRKTQASTVATGPE--VPPPWKQEGYVASSSEAEMRE 361
Query: 1186 TPVAPKKDLKIKNMGSWASLVQKHPT------TPSSTAKSSSDSFEQFRRAARE-KEERE 1238
T + ++ + VQ+ T +S + S+S + E A+E K++ +
Sbjct: 362 TTLTTSTQIRTEERWEGRYGVQEQVTISGAAGAAASVSASASYAAEAVATGAKEVKQDAD 421
Query: 1239 KALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQ 1298
K+ A + R+R+ + + E + A+R A Q Q+Q R+E ++
Sbjct: 422 KSAAVATVVAAVDMARVREPVISAVE-----QTAQRTTTTAVHIQPAQEQVRKEAEKTAV 476
Query: 1299 QQAAAVAAAATPQAQSSQPQSML-DQQRELARKREQERRRRE 1339
+ A A Q S+ + ++ +Q ++ EQ R+ E
Sbjct: 477 TKVVVAADKAKEQELKSRTKEVITTKQEQMHVTHEQIRKETE 518
Score = 37.4 bits (85), Expect = 0.099
Identities = 39/182 (21%), Positives = 72/182 (39%), Gaps = 21/182 (11%)
Query: 139 YNKPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAK------GRGRGRKETGTAKPG 192
Y+ + V A + +L +Q E+P ++T+ ++ A+ R + E
Sbjct: 174 YSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKKIEAHFDARS 233
Query: 193 VSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQ-TPP 251
++TV + Q P PP + P P + + + P P++ +P
Sbjct: 234 IATVEMVIDGAAGQQL--PHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPS 291
Query: 252 PVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKG--VKRKADTTTPTTIDPIHEPPSL 309
PV + AP P PV+S P + P+++ + + RK +T T P +
Sbjct: 292 PV----RHVRAPTPSPVRSVSPAARISTSPIRSVRSPLLMRKTQASTVAT------GPEV 341
Query: 310 PP 311
PP
Sbjct: 342 PP 343
Score = 36.2 bits (82), Expect = 0.22
Identities = 73/355 (20%), Positives = 137/355 (38%), Gaps = 44/355 (12%)
Query: 1016 GQQPPHPPPGQQPPPPQP---------AKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPL 1066
GQQ PH P + PP P+ AK Q Q SP H P H+R AP+P
Sbjct: 246 GQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVR--HVR-APTP- 301
Query: 1067 MIHSPQMSQFQSLTHQSPPQQNVQ-PKKQELRAASVVQPQPLVVV--KEEKIHSPIIRSE 1123
SP S + + P ++V+ P AS V P V K+E + +E
Sbjct: 302 ---SPVRSVSPAARISTSPIRSVRSPLLMRKTQASTVATGPEVPPPWKQEGYVASSSEAE 358
Query: 1124 PFSPSLRPEPP-KHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQ 1182
+L + E + + ++ + + A A + KQ
Sbjct: 359 MRETTLTTSTQIRTEERWEGRYGVQEQVTISGAAGAAASVSASASYAAEAVATGAKEVKQ 418
Query: 1183 EPKTPVAPKKDLKIKNMGSWA----SLVQKHPTTPSSTAKSSSDSFEQFRRAAREK---- 1234
+ A + +M S V++ ++TA + EQ R+ A +
Sbjct: 419 DADKSAAVATVVAAVDMARVREPVISAVEQTAQRTTTTAVHIQPAQEQVRKEAEKTAVTK 478
Query: 1235 ------EEREKALKAQAEHAEKEK--------ERLRQERMRSREDEDALEQARRAHEEAR 1280
+ +E+ LK++ + K E++R+E ++ + + A+ +E R
Sbjct: 479 VVVAADKAKEQELKSRTKEVITTKQEQMHVTHEQIRKETEKTFVPKVVISAAKAKEQETR 538
Query: 1281 RRQEQQQQQRQEQQQ--QQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQ 1333
+E ++Q+Q Q+ +Q+ + A + A+S++ +++ Q E +++Q
Sbjct: 539 ISEEITKKQKQVTQEAIRQETEITAASMVVVATAKSTKLETVPGAQEETTTQQDQ 593
Score = 34.3 bits (77), Expect = 0.84
Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 18/80 (22%)
Query: 747 QQAPAPVPQQPPPPPQQPPPPPPP-------QQQQQPPP-----------PPPPPSMPQQ 788
QQ P P + PP P+ P PP +QQ P P P PS +
Sbjct: 247 QQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPSPVRS 306
Query: 789 AAPAMKSSPPPFIATQVPVL 808
+PA + S P + + P+L
Sbjct: 307 VSPAARISTSPIRSVRSPLL 326
Score = 33.5 bits (75), Expect = 1.4
Identities = 24/105 (22%), Positives = 48/105 (45%), Gaps = 6/105 (5%)
Query: 923 LTSMQMQLYLQ--QLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPP 980
LT+ +++L L+ + + P P +P V + PP+ PP P + +++ PPP
Sbjct: 8923 LTTKEIKLELKPPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPTPEEKKPPPKRI 8982
Query: 981 Q--PQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPP 1023
+ + + + +P + P + +++PPPP P P
Sbjct: 8983 EVTKKAVKKDAKKVVAKPKEMTPRE--EIVKKPPPPTTLIPAKAP 9025
Score = 32.3 bits (72), Expect = 3.2
Identities = 55/295 (18%), Positives = 115/295 (38%), Gaps = 49/295 (16%)
Query: 1088 NVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLP 1147
++QP ++++R + VVV +K ++S + H H
Sbjct: 459 HIQPAQEQVRKEAEKTAVTKVVVAADKAKEQELKSRTKEVITTKQEQMHV------THEQ 512
Query: 1148 QRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLV- 1206
R E + V + VI + ++ +KQ+ T A +++ +I + AS+V
Sbjct: 513 IRKETEKTFVPKVVISAAKAKEQETRISEEITKKQKQVTQEAIRQETEI----TAASMVV 568
Query: 1207 ------QKHPTTPSSTAKSSSD------SFEQFRRAARE-------------KEER---- 1237
K T P + ++++ S+E+ + R+ KE+
Sbjct: 569 VATAKSTKLETVPGAQEETTTQQDQMHLSYEKIMKETRKTVVPKVIVATPKVKEQDLVSR 628
Query: 1238 -EKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQ- 1295
+ + + E + +E++R+E ++ A+ A+ +E R + RQEQ Q
Sbjct: 629 GREGITTKREQVQITQEKMRKEAEKTALSTIAVATAKAKEQETILRTRETMATRQEQIQV 688
Query: 1296 -------QQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQERRRREAMAA 1343
++ +A A AA QA+ +P+ + A++ E +E ++A
Sbjct: 689 THGKVDVGKKAEAVATVVAAVDQARVREPREPGHLEESYAQQTTLEYGYKERISA 743
Score = 32.3 bits (72), Expect = 3.2
Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 5/66 (7%)
Query: 851 LNQHAVVSPPALHNALPQ--QPSRPSNRAAALPPKPARPPAVSPALTQ---TPLLPQPPM 905
+ + AV SPP + + P+ P + P+P+ P AVSP T+ T + P+
Sbjct: 32655 VTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPV 32714
Query: 906 AQPPQV 911
+ PP++
Sbjct: 32715 SAPPKI 32720
Score = 32.0 bits (71), Expect = 4.2
Identities = 28/105 (26%), Positives = 41/105 (39%), Gaps = 13/105 (12%)
Query: 933 QQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQP 992
QQL PP ++ +P P PP + + QL +Q P P P + P
Sbjct: 247 QQLPHKTPP-------RIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAP 299
Query: 993 PPRPVH-LQP-MQFST----HIQQPPPPQGQQPPHPPPGQQPPPP 1031
P PV + P + ST ++ P + Q G + PPP
Sbjct: 300 TPSPVRSVSPAARISTSPIRSVRSPLLMRKTQASTVATGPEVPPP 344
Score = 32.0 bits (71), Expect = 4.2
Identities = 22/104 (21%), Positives = 46/104 (44%), Gaps = 12/104 (11%)
Query: 886 RPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLL 945
+PP + + + P+ P A PP+ + PP+ + + L L ++ +PP +
Sbjct: 8933 KPPDIPDS--RVPIPTMPIRAVPPEEI--------PPVVAPPIPLLLPTPEEKKPPPKRI 8982
Query: 946 PSVK--VQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQ 987
K V+ + P + ++++ ++PPPP P P+
Sbjct: 8983 EVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPE 9026
Score = 31.2 bits (69), Expect = 7.1
Identities = 17/53 (32%), Positives = 26/53 (49%), Gaps = 3/53 (5%)
Query: 761 PQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLP 813
P + PP PP+ + + P PP S+ +A A + SP P + PV + P
Sbjct: 250 PHKTPPRIPPKPKSRSPTPP---SIAAKAQLARQQSPSPIRHSPSPVRHVRAP 299
Score = 31.2 bits (69), Expect = 7.1
Identities = 54/270 (20%), Positives = 100/270 (37%), Gaps = 42/270 (15%)
Query: 1108 VVVKEEKIHSPIIRSEPFSPSLRP-EPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPE 1166
V +E ++S I R EP + E + IK + P P+ + P+ P
Sbjct: 8895 VTPDDEGVYSVIARLEPRGEARSTAELYLTTKEIKLELKPPDIPDSRVPIPTMPIRAVPP 8954
Query: 1167 QNAPPPGA-------PDKDKQKQEPK----TPVAPKKD-----LKIKNMGSWASLVQKHP 1210
+ PP A P +++K PK T A KKD K K M +V+K P
Sbjct: 8955 EEIPPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPP 9014
Query: 1211 --------TTPSSTAKSSSDSFEQFRRAAREKE-EREKALKAQAEHAEKEKERLRQERMR 1261
P SS + R+KE ++EK + + A +++R+ E
Sbjct: 9015 PPTTLIPAKAPEIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVFIESFE 9074
Query: 1262 SREDEDALEQARRAHE----------------EARRRQEQQQQQRQEQQQQQQQQAAAVA 1305
DE +E E EA++ ++ ++ E+ Q+ ++
Sbjct: 9075 EPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYD 9134
Query: 1306 AAATPQAQSSQPQSMLDQQRELARKREQER 1335
++ Q + ++ Q+E+ + + +
Sbjct: 9135 EGEEEWEEAYQEREVIQVQKEVYEESHERK 9164
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 131 bits (329), Expect = 5e-30
Identities = 196/715 (27%), Positives = 251/715 (35%), Gaps = 151/715 (21%)
Query: 624 KLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYV---TSCLRKKRK 680
K P GR I + S +NS P K T+++ + V S K K
Sbjct: 36 KQPASPDGRTSPINEDIRSSGRNS-PSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNK 94
Query: 681 PQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHH 740
Q EKV A ++ +SS+ + E S +S + S+ G K
Sbjct: 95 RQREKV---ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPK--- 148
Query: 741 HHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPF 800
+ Q P P QQQ PP P PA S+PP
Sbjct: 149 ----DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPG- 203
Query: 801 IATQVPVLEPQLPGSVFDPIGH------------FTQPILHLPQPELPPHLPQ-PPEHST 847
Q+P P + P G T P+ H + P PQ PP
Sbjct: 204 -TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHP 262
Query: 848 PPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLL-----PQ 902
PPH + H + P QPS PS+ A PP + P +L PLL PQ
Sbjct: 263 PPHPSPHPPLQP---LTGSAGQPSAPSH---AQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 316
Query: 903 ----PPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPL 958
PP A Q L A P TS+Q+ LQ QPP + Q PP PL
Sbjct: 317 PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP-------REQPLPPAPL 369
Query: 959 PPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQ-PMQFSTHIQQPPPP--- 1014
P PPP P PQ P Q H+ PP HL P FS + PPPP
Sbjct: 370 AMP----------HIKPPPTTPIPQLPAPQAHKHPP---HLSGPSPFSMNANLPPPPALK 416
Query: 1015 -----QGQQPP--HPPPGQ-----QPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREA 1062
PP HPPP Q QP P PA+P + Q + P S P TG + A
Sbjct: 417 PLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHP-PTGLHQVA 475
Query: 1063 PSPLMIHSPQM----------SQFQSLTHQSPPQQNVQPKKQELRAA--SVVQ----PQP 1106
P P P + + + T + P + QP A+ S+ P P
Sbjct: 476 PQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLP 535
Query: 1107 LVVVKEEKIHSPIIRSEPFSPSLRPEPPK-HPESIKAPVHLPQRPEM-KPVDVGRPVIRP 1164
V +KEE + EP SP P P P + P H Q K +D G
Sbjct: 536 TVQIKEEALDD---AEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRG------ 586
Query: 1165 PEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSF 1224
N+ + DL P S AK ++
Sbjct: 587 --YNS-------------------CARTDLYFM------------PLAGSKLAKKREEAI 613
Query: 1225 EQFRRAAREK--EEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHE 1277
E+ +R A +K EERE+ EKEKER R ER R RE E A + + AHE
Sbjct: 614 EKAKREAEQKAREERER-------EKEKEKERER-EREREREAERAAKASSSAHE 660
Score = 120 bits (300), Expect = 1e-26
Identities = 165/676 (24%), Positives = 240/676 (35%), Gaps = 157/676 (23%)
Query: 679 RKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKH 738
+K + +++ S+ +G SS+S S ++ SSD +D + + S P +
Sbjct: 113 KKTKTQEISRPNSPSEGEG-ESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDS 171
Query: 739 HHHHHQQMQQAPAPVPQQPP---PPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKS 795
QQM QA P Q P P P PP P Q P P P ++P Q +P
Sbjct: 172 DSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP--QLPTPGPTPSATAVPPQGSPTASQ 229
Query: 796 SPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHA 855
+P +PQ P T P+ H H+ Q
Sbjct: 230 APN----------QPQAP----------TAPVPHT-------------------HIQQ-- 248
Query: 856 VVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLED 915
PALH PQ+P P PP P+ P + P P AQPP L
Sbjct: 249 ---APALH---PQRPPSPHP-----PPHPSPHPPLQPLTGSAGQPSAPSHAQPP---LHG 294
Query: 916 EEPPAPPLTSMQMQLYLQQLQKVQPPTPL-LPSVKVQSQPP---PPLPPPPH-----PSV 966
+ PP P S+Q LQ PP P LP Q Q P P PH P+
Sbjct: 295 QGPPGPH--SLQAGPLLQH---PGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
Query: 967 QQQLQQQPPPPPPPQPQPPPQQQH-QPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPG 1025
Q LQ Q PP P P P H +PPP +T I Q P PQ + P G
Sbjct: 350 QSALQSQQPPREQPLPPAPLAMPHIKPPP----------TTPIPQLPAPQAHKHPPHLSG 399
Query: 1026 QQP-------PPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQS 1078
P PPP KP + HH P H P PL + PQ S
Sbjct: 400 PSPFSMNANLPPPPALKPLSSLSTHHPPSAH-------------PPPLQL-MPQSQPLPS 445
Query: 1079 LTHQSP---PQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPE--P 1133
Q P QN+ P + Q P P PF P P P
Sbjct: 446 SPAQPPGLTQSQNLPPPPASHPPTGLHQVAP----------QPPFAQHPFVPGGPPPITP 495
Query: 1134 PKHPESIKAPVH---LPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDK---QKQEPKTP 1187
P P + P Q P G + + P P K++ +EP++P
Sbjct: 496 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGG--SSCPLPTVQIKEEALDDAEEPESP 553
Query: 1188 VAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEH 1247
P + P+ + + S + + R +
Sbjct: 554 PPPPRS----------------PSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYF 597
Query: 1248 AEKEKERLRQERMRSREDEDALEQARR-----AHEEARRRQEQQQQQRQEQQQQQQQQAA 1302
+L ++R E+A+E+A+R A EE R +E+++++ +E++++++ + A
Sbjct: 598 MPLAGSKLAKKR------EEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERA 651
Query: 1303 AVAAAATPQAQSSQPQ 1318
A A+++ + + S PQ
Sbjct: 652 AKASSSAHEGRLSDPQ 667
Score = 52.8 bits (125), Expect = 2e-06
Identities = 50/165 (30%), Positives = 58/165 (35%), Gaps = 35/165 (21%)
Query: 198 NTTQASTPPQTQTPQPNPPPVQA----TPHPF--PAVTPDLIVQ--TPVMTVVPPQPLQT 249
N + + + Q Q Q PP +QA TP P P TP L TP T VPPQ T
Sbjct: 167 NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPT 226
Query: 250 PPPVPPQPQPPPAPAPQP-VQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPS 308
P QPQ P AP P +Q P + P P+ P H P
Sbjct: 227 ASQAPNQPQAPTAPVPHTHIQQAPALHPQRP-----------------PSPHPPPHPSPH 269
Query: 309 LPPEPKTTKLGQRRESSR---------PVKPPKKDVPDSQQHPAP 344
P +P T GQ S P P QHP P
Sbjct: 270 PPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP 314
Score = 48.9 bits (115), Expect = 3e-05
Identities = 49/155 (31%), Positives = 58/155 (37%), Gaps = 22/155 (14%)
Query: 205 PPQTQTPQP--NPPPVQATPHP---FPAVTPDLIVQTPVMTV-VPPQPLQTPPPVPPQPQ 258
PPQ Q P A PH PA L Q P +PP PL P PP
Sbjct: 321 PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTT 380
Query: 259 P-PPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPI-----HEPPSLPPE 312
P P PAPQ HPP ++ P P A+ P + P+ H PPS P
Sbjct: 381 PIPQLPAPQ-AHKHPPHLSG-PSP------FSMNANLPPPPALKPLSSLSTHHPPSAHPP 432
Query: 313 PKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKS 347
P + S P +PP + SQ P P S
Sbjct: 433 PLQLMPQSQPLPSSPAQPP--GLTQSQNLPPPPAS 465
Score = 40.8 bits (94), Expect = 0.009
Identities = 42/153 (27%), Positives = 55/153 (35%), Gaps = 35/153 (22%)
Query: 189 AKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPL- 247
A GV+ P++ TP Q TP P P P P + Q P P P+
Sbjct: 189 APTGVTPAPSSAPPGTP-QLPTPGPTPSATAVPPQGSPTAS-----QAPNQPQAPTAPVP 242
Query: 248 -----QTP---PPVPPQPQPP--PAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTP 297
Q P P PP P PP P+P HPP+ QP+ G P
Sbjct: 243 HTHIQQAPALHPQRPPSPHPPPHPSP-------HPPL-----QPLTGSAGQPSAPSHAQP 290
Query: 298 TTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKP 330
P+H PP P + + G + P +P
Sbjct: 291 ----PLHGQG--PPGPHSLQAGPLLQHPGPPQP 317
Score = 40.4 bits (93), Expect = 0.012
Identities = 57/243 (23%), Positives = 100/243 (41%), Gaps = 33/243 (13%)
Query: 459 DEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSS-----DSSSDSDSSTDD-----SEEERA 508
+EPE P SP+ P PT V P +S S+ D +S + TD + + A
Sbjct: 548 EEPESPPPPPRSPS-PEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLA 606
Query: 509 QRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEP 568
++ E E+ K EQ A ++ + ++KEK+K+ +++ + +R+ E S A E
Sbjct: 607 KKREEAIEKAKREAEQKA-----REEREREKEKEKEREREREREREAERAAKASSSAHEG 661
Query: 569 PPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINK---- 624
+ + + S EP P P Y + + +S + + N+
Sbjct: 662 RLSDPQLSGPGHMRPS-FEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPF 720
Query: 625 -LPGEKLGRVVHIIQSREPSLKNSNPD--EIEIDFETLKPSTLRELERYVTSCLRKKRKP 681
+P L ++ P L N +P E E+ ++ +RE E LR++ KP
Sbjct: 721 YMP---LNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERE------LRERMKP 771
Query: 682 QAE 684
E
Sbjct: 772 GFE 774
Score = 37.0 bits (84), Expect = 0.13
Identities = 83/409 (20%), Positives = 133/409 (32%), Gaps = 47/409 (11%)
Query: 197 PNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQ 256
P + A+ PP P P +T HP P+ P + P +P P Q P Q
Sbjct: 402 PFSMNANLPPP---PALKPLSSLSTHHP-PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQ 457
Query: 257 PQPPPAP----------APQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEP 306
PPP APQP + P + P P+ T P+T P P
Sbjct: 458 NLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPI---------TPPTCPSTSTPPAGP 508
Query: 307 PSLPPEPKTTKLGQRRE----SSRP-----VKPPKKDVPDSQQHPAPEKSSKVSEQLKCC 357
+ P + SS P +K D + + P P S E
Sbjct: 509 GTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEP---- 564
Query: 358 SGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLE---AREYRD 414
+ HA+ + FYK +D D+ P+ S + K E + R+
Sbjct: 565 ----TVVDTPSHASQSARFYKHLD-RGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKRE 619
Query: 415 AQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAV- 473
A++ + R K + E A + +P+ P+
Sbjct: 620 AEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFE 679
Query: 474 PPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQ 533
PPPT + A P + + R L LA
Sbjct: 680 PPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLY 739
Query: 534 N-KPKKKEKDKKEKK-KEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSN 580
N P +E++ +E++ +E+ R+ E+ E K + PP+ + ++N
Sbjct: 740 NVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPAAN 788
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 131 bits (329), Expect = 5e-30
Identities = 196/715 (27%), Positives = 251/715 (35%), Gaps = 151/715 (21%)
Query: 624 KLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYV---TSCLRKKRK 680
K P GR I + S +NS P K T+++ + V S K K
Sbjct: 590 KQPASPDGRTSPINEDIRSSGRNS-PSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNK 648
Query: 681 PQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHH 740
Q EKV A ++ +SS+ + E S +S + S+ G K
Sbjct: 649 RQREKV---ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPK--- 702
Query: 741 HHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPF 800
+ Q P P QQQ PP P PA S+PP
Sbjct: 703 ----DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPG- 757
Query: 801 IATQVPVLEPQLPGSVFDPIGH------------FTQPILHLPQPELPPHLPQ-PPEHST 847
Q+P P + P G T P+ H + P PQ PP
Sbjct: 758 -TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHP 816
Query: 848 PPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLL-----PQ 902
PPH + H + P QPS PS+ A PP + P +L PLL PQ
Sbjct: 817 PPHPSPHPPLQP---LTGSAGQPSAPSH---AQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 870
Query: 903 ----PPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPL 958
PP A Q L A P TS+Q+ LQ QPP + Q PP PL
Sbjct: 871 PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP-------REQPLPPAPL 923
Query: 959 PPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQ-PMQFSTHIQQPPPP--- 1014
P PPP P PQ P Q H+ PP HL P FS + PPPP
Sbjct: 924 AMP----------HIKPPPTTPIPQLPAPQAHKHPP---HLSGPSPFSMNANLPPPPALK 970
Query: 1015 -----QGQQPP--HPPPGQ-----QPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREA 1062
PP HPPP Q QP P PA+P + Q + P S P TG + A
Sbjct: 971 PLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHP-PTGLHQVA 1029
Query: 1063 PSPLMIHSPQM----------SQFQSLTHQSPPQQNVQPKKQELRAA--SVVQ----PQP 1106
P P P + + + T + P + QP A+ S+ P P
Sbjct: 1030 PQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLP 1089
Query: 1107 LVVVKEEKIHSPIIRSEPFSPSLRPEPPK-HPESIKAPVHLPQRPEM-KPVDVGRPVIRP 1164
V +KEE + EP SP P P P + P H Q K +D G
Sbjct: 1090 TVQIKEEALDD---AEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRG------ 1140
Query: 1165 PEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSF 1224
N+ + DL P S AK ++
Sbjct: 1141 --YNS-------------------CARTDLYFM------------PLAGSKLAKKREEAI 1167
Query: 1225 EQFRRAAREK--EEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHE 1277
E+ +R A +K EERE+ EKEKER R ER R RE E A + + AHE
Sbjct: 1168 EKAKREAEQKAREERER-------EKEKEKERER-EREREREAERAAKASSSAHE 1214
Score = 121 bits (304), Expect = 4e-27
Identities = 201/882 (22%), Positives = 305/882 (34%), Gaps = 182/882 (20%)
Query: 482 PPSSSDSSSDSSSDSDSSTDDSEEE------RAQRLAELQEQLKAVHEQLAALSQPQQNK 535
PPSS S+S+ D ++DSE+E R ++ E + + + +
Sbjct: 477 PPSSEFLDLSSASEDDFDSEDSEQELKGYACRHCFTTTSKDWHHGGRENILLCTDCRIHF 536
Query: 536 PKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVS---KKEPAPMK 592
K E EK + + + + +T+++ S S + KK+PA
Sbjct: 537 KKYGELPPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPD 596
Query: 593 SKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEI 652
+ P E + S N E + + ++ S SN +
Sbjct: 597 GRTSPINED-----IRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQR 651
Query: 653 EIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSS 712
E S E +R +K + +++ S+ +G SS+S S ++ SS
Sbjct: 652 E-----KVASDTEEADR------TSSKKTKTQEISRPNSPSEGEG-ESSDSRSVNDEGSS 699
Query: 713 DSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPP---PPPQQPPPPPP 769
D +D + + S P + QQM QA P Q P P P PP P
Sbjct: 700 DPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP 759
Query: 770 PQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILH 829
Q P P P ++P Q +P +P +PQ P T P+ H
Sbjct: 760 --QLPTPGPTPSATAVPPQGSPTASQAPN----------QPQAP----------TAPVPH 797
Query: 830 LPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPA 889
H+ Q PALH PQ+P P PP P+ P
Sbjct: 798 T-------------------HIQQ-----APALH---PQRPPSPHP-----PPHPSPHPP 825
Query: 890 VSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPL-LPSV 948
+ P P AQPP L + PP P S+Q LQ PP P LP
Sbjct: 826 LQPLTGSAGQPSAPSHAQPP---LHGQGPPGPH--SLQAGPLLQH---PGPPQPFGLPPQ 877
Query: 949 KVQSQPP---PPLPPPPH-----PSVQQQLQQQPPPPPPPQPQPPPQQQH-QPPPRPVHL 999
Q Q P P PH P+ Q LQ Q PP P P P H +PPP
Sbjct: 878 ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPP----- 932
Query: 1000 QPMQFSTHIQQPPPPQGQQPPHPPPGQQP-------PPPQPAKPQQVIQHHHSPRHHKSD 1052
+T I Q P PQ + P G P PPP KP + HH P H
Sbjct: 933 -----TTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAH--- 984
Query: 1053 PYSTGHLREAPSPLMIHSPQMSQFQSLTHQSP---PQQNVQPKKQELRAASVVQPQPLVV 1109
P PL + PQ S Q P QN+ P + Q P
Sbjct: 985 ----------PPPLQL-MPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAP--- 1030
Query: 1110 VKEEKIHSPIIRSEPFSPSLRPE--PPKHPESIKAPVH---LPQRPEMKPVDVGRPVIRP 1164
P PF P P PP P + P Q P G +
Sbjct: 1031 -------QPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGG 1083
Query: 1165 PEQNAPPPGAPDKDK---QKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSS 1221
+ P P K++ +EP++P P + P+ + + S
Sbjct: 1084 --SSCPLPTVQIKEEALDDAEEPESPPPPPRS----------------PSPEPTVVDTPS 1125
Query: 1222 DSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARR-----AH 1276
+ + R + +L ++R E+A+E+A+R A
Sbjct: 1126 HASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKR------EEAIEKAKREAEQKAR 1179
Query: 1277 EEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQ 1318
EE R +E+++++ +E++++++ + AA A+++ + + S PQ
Sbjct: 1180 EEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQ 1221
Score = 52.8 bits (125), Expect = 2e-06
Identities = 50/165 (30%), Positives = 58/165 (35%), Gaps = 35/165 (21%)
Query: 198 NTTQASTPPQTQTPQPNPPPVQA----TPHPF--PAVTPDLIVQ--TPVMTVVPPQPLQT 249
N + + + Q Q Q PP +QA TP P P TP L TP T VPPQ T
Sbjct: 721 NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPT 780
Query: 250 PPPVPPQPQPPPAPAPQP-VQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPS 308
P QPQ P AP P +Q P + P P+ P H P
Sbjct: 781 ASQAPNQPQAPTAPVPHTHIQQAPALHPQRP-----------------PSPHPPPHPSPH 823
Query: 309 LPPEPKTTKLGQRRESSR---------PVKPPKKDVPDSQQHPAP 344
P +P T GQ S P P QHP P
Sbjct: 824 PPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP 868
Score = 48.9 bits (115), Expect = 3e-05
Identities = 49/155 (31%), Positives = 58/155 (37%), Gaps = 22/155 (14%)
Query: 205 PPQTQTPQP--NPPPVQATPHP---FPAVTPDLIVQTPVMTV-VPPQPLQTPPPVPPQPQ 258
PPQ Q P A PH PA L Q P +PP PL P PP
Sbjct: 875 PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTT 934
Query: 259 P-PPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPI-----HEPPSLPPE 312
P P PAPQ HPP ++ P P A+ P + P+ H PPS P
Sbjct: 935 PIPQLPAPQ-AHKHPPHLSG-PSP------FSMNANLPPPPALKPLSSLSTHHPPSAHPP 986
Query: 313 PKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKS 347
P + S P +PP + SQ P P S
Sbjct: 987 PLQLMPQSQPLPSSPAQPP--GLTQSQNLPPPPAS 1019
Score = 40.8 bits (94), Expect = 0.009
Identities = 42/153 (27%), Positives = 55/153 (35%), Gaps = 35/153 (22%)
Query: 189 AKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPL- 247
A GV+ P++ TP Q TP P P P P + Q P P P+
Sbjct: 743 APTGVTPAPSSAPPGTP-QLPTPGPTPSATAVPPQGSPTAS-----QAPNQPQAPTAPVP 796
Query: 248 -----QTP---PPVPPQPQPP--PAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTP 297
Q P P PP P PP P+P HPP+ QP+ G P
Sbjct: 797 HTHIQQAPALHPQRPPSPHPPPHPSP-------HPPL-----QPLTGSAGQPSAPSHAQP 844
Query: 298 TTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKP 330
P+H PP P + + G + P +P
Sbjct: 845 ----PLHGQG--PPGPHSLQAGPLLQHPGPPQP 871
Score = 40.4 bits (93), Expect = 0.012
Identities = 57/243 (23%), Positives = 100/243 (41%), Gaps = 33/243 (13%)
Query: 459 DEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSS-----DSSSDSDSSTDD-----SEEERA 508
+EPE P SP+ P PT V P +S S+ D +S + TD + + A
Sbjct: 1102 EEPESPPPPPRSPS-PEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLA 1160
Query: 509 QRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEP 568
++ E E+ K EQ A ++ + ++KEK+K+ +++ + +R+ E S A E
Sbjct: 1161 KKREEAIEKAKREAEQKA-----REEREREKEKEKEREREREREREAERAAKASSSAHEG 1215
Query: 569 PPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINK---- 624
+ + + S EP P P Y + + +S + + N+
Sbjct: 1216 RLSDPQLSGPGHMRPS-FEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPF 1274
Query: 625 -LPGEKLGRVVHIIQSREPSLKNSNPD--EIEIDFETLKPSTLRELERYVTSCLRKKRKP 681
+P L ++ P L N +P E E+ ++ +RE E LR++ KP
Sbjct: 1275 YMP---LNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERE------LRERMKP 1325
Query: 682 QAE 684
E
Sbjct: 1326 GFE 1328
Score = 37.0 bits (84), Expect = 0.13
Identities = 83/409 (20%), Positives = 133/409 (32%), Gaps = 47/409 (11%)
Query: 197 PNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQ 256
P + A+ PP P P +T HP P+ P + P +P P Q P Q
Sbjct: 956 PFSMNANLPPP---PALKPLSSLSTHHP-PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQ 1011
Query: 257 PQPPPAP----------APQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEP 306
PPP APQP + P + P P+ T P+T P P
Sbjct: 1012 NLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPI---------TPPTCPSTSTPPAGP 1062
Query: 307 PSLPPEPKTTKLGQRRE----SSRP-----VKPPKKDVPDSQQHPAPEKSSKVSEQLKCC 357
+ P + SS P +K D + + P P S E
Sbjct: 1063 GTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEP---- 1118
Query: 358 SGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLE---AREYRD 414
+ HA+ + FYK +D D+ P+ S + K E + R+
Sbjct: 1119 ----TVVDTPSHASQSARFYKHLD-RGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKRE 1173
Query: 415 AQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAV- 473
A++ + R K + E A + +P+ P+
Sbjct: 1174 AEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFE 1233
Query: 474 PPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQ 533
PPPT + A P + + R L LA
Sbjct: 1234 PPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLY 1293
Query: 534 N-KPKKKEKDKKEKK-KEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSN 580
N P +E++ +E++ +E+ R+ E+ E K + PP+ + ++N
Sbjct: 1294 NVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPAAN 1342
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 131 bits (329), Expect = 5e-30
Identities = 196/715 (27%), Positives = 251/715 (35%), Gaps = 151/715 (21%)
Query: 624 KLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYV---TSCLRKKRK 680
K P GR I + S +NS P K T+++ + V S K K
Sbjct: 590 KQPASPDGRTSPINEDIRSSGRNS-PSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNK 648
Query: 681 PQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHH 740
Q EKV A ++ +SS+ + E S +S + S+ G K
Sbjct: 649 RQREKV---ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPK--- 702
Query: 741 HHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPF 800
+ Q P P QQQ PP P PA S+PP
Sbjct: 703 ----DIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPG- 757
Query: 801 IATQVPVLEPQLPGSVFDPIGH------------FTQPILHLPQPELPPHLPQ-PPEHST 847
Q+P P + P G T P+ H + P PQ PP
Sbjct: 758 -TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHP 816
Query: 848 PPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLL-----PQ 902
PPH + H + P QPS PS+ A PP + P +L PLL PQ
Sbjct: 817 PPHPSPHPPLQP---LTGSAGQPSAPSH---AQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 870
Query: 903 ----PPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPL 958
PP A Q L A P TS+Q+ LQ QPP + Q PP PL
Sbjct: 871 PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP-------REQPLPPAPL 923
Query: 959 PPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQ-PMQFSTHIQQPPPP--- 1014
P PPP P PQ P Q H+ PP HL P FS + PPPP
Sbjct: 924 AMP----------HIKPPPTTPIPQLPAPQAHKHPP---HLSGPSPFSMNANLPPPPALK 970
Query: 1015 -----QGQQPP--HPPPGQ-----QPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREA 1062
PP HPPP Q QP P PA+P + Q + P S P TG + A
Sbjct: 971 PLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHP-PTGLHQVA 1029
Query: 1063 PSPLMIHSPQM----------SQFQSLTHQSPPQQNVQPKKQELRAA--SVVQ----PQP 1106
P P P + + + T + P + QP A+ S+ P P
Sbjct: 1030 PQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLP 1089
Query: 1107 LVVVKEEKIHSPIIRSEPFSPSLRPEPPK-HPESIKAPVHLPQRPEM-KPVDVGRPVIRP 1164
V +KEE + EP SP P P P + P H Q K +D G
Sbjct: 1090 TVQIKEEALDD---AEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRG------ 1140
Query: 1165 PEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSF 1224
N+ + DL P S AK ++
Sbjct: 1141 --YNS-------------------CARTDLYFM------------PLAGSKLAKKREEAI 1167
Query: 1225 EQFRRAAREK--EEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHE 1277
E+ +R A +K EERE+ EKEKER R ER R RE E A + + AHE
Sbjct: 1168 EKAKREAEQKAREERER-------EKEKEKERER-EREREREAERAAKASSSAHE 1214
Score = 121 bits (304), Expect = 4e-27
Identities = 201/882 (22%), Positives = 305/882 (34%), Gaps = 182/882 (20%)
Query: 482 PPSSSDSSSDSSSDSDSSTDDSEEE------RAQRLAELQEQLKAVHEQLAALSQPQQNK 535
PPSS S+S+ D ++DSE+E R ++ E + + + +
Sbjct: 477 PPSSEFLDLSSASEDDFDSEDSEQELKGYACRHCFTTTSKDWHHGGRENILLCTDCRIHF 536
Query: 536 PKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVS---KKEPAPMK 592
K E EK + + + + +T+++ S S + KK+PA
Sbjct: 537 KKYGELPPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPD 596
Query: 593 SKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEI 652
+ P E + S N E + + ++ S SN +
Sbjct: 597 GRTSPINED-----IRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQR 651
Query: 653 EIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSS 712
E S E +R +K + +++ S+ +G SS+S S ++ SS
Sbjct: 652 E-----KVASDTEEADR------TSSKKTKTQEISRPNSPSEGEG-ESSDSRSVNDEGSS 699
Query: 713 DSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPP---PPPQQPPPPPP 769
D +D + + S P + QQM QA P Q P P P PP P
Sbjct: 700 DPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP 759
Query: 770 PQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILH 829
Q P P P ++P Q +P +P +PQ P T P+ H
Sbjct: 760 --QLPTPGPTPSATAVPPQGSPTASQAPN----------QPQAP----------TAPVPH 797
Query: 830 LPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPA 889
H+ Q PALH PQ+P P PP P+ P
Sbjct: 798 T-------------------HIQQ-----APALH---PQRPPSPHP-----PPHPSPHPP 825
Query: 890 VSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPL-LPSV 948
+ P P AQPP L + PP P S+Q LQ PP P LP
Sbjct: 826 LQPLTGSAGQPSAPSHAQPP---LHGQGPPGPH--SLQAGPLLQH---PGPPQPFGLPPQ 877
Query: 949 KVQSQPP---PPLPPPPH-----PSVQQQLQQQPPPPPPPQPQPPPQQQH-QPPPRPVHL 999
Q Q P P PH P+ Q LQ Q PP P P P H +PPP
Sbjct: 878 ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPP----- 932
Query: 1000 QPMQFSTHIQQPPPPQGQQPPHPPPGQQP-------PPPQPAKPQQVIQHHHSPRHHKSD 1052
+T I Q P PQ + P G P PPP KP + HH P H
Sbjct: 933 -----TTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAH--- 984
Query: 1053 PYSTGHLREAPSPLMIHSPQMSQFQSLTHQSP---PQQNVQPKKQELRAASVVQPQPLVV 1109
P PL + PQ S Q P QN+ P + Q P
Sbjct: 985 ----------PPPLQL-MPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAP--- 1030
Query: 1110 VKEEKIHSPIIRSEPFSPSLRPE--PPKHPESIKAPVH---LPQRPEMKPVDVGRPVIRP 1164
P PF P P PP P + P Q P G +
Sbjct: 1031 -------QPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGG 1083
Query: 1165 PEQNAPPPGAPDKDK---QKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSS 1221
+ P P K++ +EP++P P + P+ + + S
Sbjct: 1084 --SSCPLPTVQIKEEALDDAEEPESPPPPPRS----------------PSPEPTVVDTPS 1125
Query: 1222 DSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARR-----AH 1276
+ + R + +L ++R E+A+E+A+R A
Sbjct: 1126 HASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKR------EEAIEKAKREAEQKAR 1179
Query: 1277 EEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQ 1318
EE R +E+++++ +E++++++ + AA A+++ + + S PQ
Sbjct: 1180 EEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQ 1221
Score = 52.8 bits (125), Expect = 2e-06
Identities = 50/165 (30%), Positives = 58/165 (35%), Gaps = 35/165 (21%)
Query: 198 NTTQASTPPQTQTPQPNPPPVQA----TPHPF--PAVTPDLIVQ--TPVMTVVPPQPLQT 249
N + + + Q Q Q PP +QA TP P P TP L TP T VPPQ T
Sbjct: 721 NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPT 780
Query: 250 PPPVPPQPQPPPAPAPQP-VQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPS 308
P QPQ P AP P +Q P + P P+ P H P
Sbjct: 781 ASQAPNQPQAPTAPVPHTHIQQAPALHPQRP-----------------PSPHPPPHPSPH 823
Query: 309 LPPEPKTTKLGQRRESSR---------PVKPPKKDVPDSQQHPAP 344
P +P T GQ S P P QHP P
Sbjct: 824 PPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP 868
Score = 48.9 bits (115), Expect = 3e-05
Identities = 49/155 (31%), Positives = 58/155 (37%), Gaps = 22/155 (14%)
Query: 205 PPQTQTPQP--NPPPVQATPHP---FPAVTPDLIVQTPVMTV-VPPQPLQTPPPVPPQPQ 258
PPQ Q P A PH PA L Q P +PP PL P PP
Sbjct: 875 PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTT 934
Query: 259 P-PPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPI-----HEPPSLPPE 312
P P PAPQ HPP ++ P P A+ P + P+ H PPS P
Sbjct: 935 PIPQLPAPQ-AHKHPPHLSG-PSP------FSMNANLPPPPALKPLSSLSTHHPPSAHPP 986
Query: 313 PKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKS 347
P + S P +PP + SQ P P S
Sbjct: 987 PLQLMPQSQPLPSSPAQPP--GLTQSQNLPPPPAS 1019
Score = 40.8 bits (94), Expect = 0.009
Identities = 42/153 (27%), Positives = 55/153 (35%), Gaps = 35/153 (22%)
Query: 189 AKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPL- 247
A GV+ P++ TP Q TP P P P P + Q P P P+
Sbjct: 743 APTGVTPAPSSAPPGTP-QLPTPGPTPSATAVPPQGSPTAS-----QAPNQPQAPTAPVP 796
Query: 248 -----QTP---PPVPPQPQPP--PAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTP 297
Q P P PP P PP P+P HPP+ QP+ G P
Sbjct: 797 HTHIQQAPALHPQRPPSPHPPPHPSP-------HPPL-----QPLTGSAGQPSAPSHAQP 844
Query: 298 TTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKP 330
P+H PP P + + G + P +P
Sbjct: 845 ----PLHGQG--PPGPHSLQAGPLLQHPGPPQP 871
Score = 40.4 bits (93), Expect = 0.012
Identities = 57/243 (23%), Positives = 100/243 (41%), Gaps = 33/243 (13%)
Query: 459 DEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSS-----DSSSDSDSSTDD-----SEEERA 508
+EPE P SP+ P PT V P +S S+ D +S + TD + + A
Sbjct: 1102 EEPESPPPPPRSPS-PEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLA 1160
Query: 509 QRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEP 568
++ E E+ K EQ A ++ + ++KEK+K+ +++ + +R+ E S A E
Sbjct: 1161 KKREEAIEKAKREAEQKA-----REEREREKEKEKEREREREREREAERAAKASSSAHEG 1215
Query: 569 PPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINK---- 624
+ + + S EP P P Y + + +S + + N+
Sbjct: 1216 RLSDPQLSGPGHMRPS-FEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPF 1274
Query: 625 -LPGEKLGRVVHIIQSREPSLKNSNPD--EIEIDFETLKPSTLRELERYVTSCLRKKRKP 681
+P L ++ P L N +P E E+ ++ +RE E LR++ KP
Sbjct: 1275 YMP---LNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERE------LRERMKP 1325
Query: 682 QAE 684
E
Sbjct: 1326 GFE 1328
Score = 37.0 bits (84), Expect = 0.13
Identities = 83/409 (20%), Positives = 133/409 (32%), Gaps = 47/409 (11%)
Query: 197 PNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQ 256
P + A+ PP P P +T HP P+ P + P +P P Q P Q
Sbjct: 956 PFSMNANLPPP---PALKPLSSLSTHHP-PSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQ 1011
Query: 257 PQPPPAP----------APQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEP 306
PPP APQP + P + P P+ T P+T P P
Sbjct: 1012 NLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPI---------TPPTCPSTSTPPAGP 1062
Query: 307 PSLPPEPKTTKLGQRRE----SSRP-----VKPPKKDVPDSQQHPAPEKSSKVSEQLKCC 357
+ P + SS P +K D + + P P S E
Sbjct: 1063 GTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEP---- 1118
Query: 358 SGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLE---AREYRD 414
+ HA+ + FYK +D D+ P+ S + K E + R+
Sbjct: 1119 ----TVVDTPSHASQSARFYKHLD-RGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKRE 1173
Query: 415 AQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAV- 473
A++ + R K + E A + +P+ P+
Sbjct: 1174 AEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFE 1233
Query: 474 PPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQ 533
PPPT + A P + + R L LA
Sbjct: 1234 PPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLY 1293
Query: 534 N-KPKKKEKDKKEKK-KEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSN 580
N P +E++ +E++ +E+ R+ E+ E K + PP+ + ++N
Sbjct: 1294 NVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPAAN 1342
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 130 bits (327), Expect = 9e-30
Identities = 143/522 (27%), Positives = 206/522 (39%), Gaps = 93/522 (17%)
Query: 743 HQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAA-----PAMKS-- 795
+++M P P PPP++ P PPP+ + PPP P+ P A P +S
Sbjct: 435 NEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPL 494
Query: 796 SPPPFIATQVPVLEPQLPGSVFDPI--GHFTQPILHLPQPELPPHLPQPPEHS--TPPHL 851
SPPP + L P S F P+ + P P P L L PPE S +PP
Sbjct: 495 SPPP----EESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPF- 549
Query: 852 NQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQ-------PP 904
+ + +SPP + P+ P A+ L P P P +SP ++P+ P PP
Sbjct: 550 -EESPLSPPP-----EELPTSPPPEASRLSPPPEESP-MSPPPEESPMSPPPEASRLFPP 602
Query: 905 MAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPP--TPLLPSVKV----------QS 952
+ P +E P +PP + ++ + PP +P+ P +V +
Sbjct: 603 FEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRL 662
Query: 953 QPPP---PLPPPPHPS----VQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQ-PMQF 1004
PPP PL PPP S + + PPP P PP PPP + P++
Sbjct: 663 SPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEE 722
Query: 1005 STHIQQPPPPQ---GQQPPHPPPGQQPP--PPQPAKPQ---QVIQHHHSPR--------- 1047
S + P PQ + PH P + P P+P +P Q + H SP+
Sbjct: 723 SPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAV 782
Query: 1048 ---HHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQP 1104
H S HL P L + SPQ + P + QP++ L S
Sbjct: 783 PEEPHLSPQAEGPHLSPQPEELHL-SPQTEEPHLSPVPEEPCLSPQPEESHLSPQS---E 838
Query: 1105 QPLVVVKEEKIH-SPIIRSEPFSPSLRPE-PPKHPESIKAPVHL-----PQRPEMKPV-- 1155
+P + + E+ H SP + P SP RPE PP+ P AP L P P + P+
Sbjct: 839 EPCLSPRPEESHLSPELEKPPLSP--RPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLG 896
Query: 1156 -----DVGRPVIRPPEQNAP--PPGAPDKDKQKQEPKTPVAP 1190
+ G P + P + P P G P Q P P+ P
Sbjct: 897 EPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLM-PPDPLPP 937
Score = 125 bits (313), Expect = 4e-28
Identities = 135/500 (27%), Positives = 196/500 (39%), Gaps = 104/500 (20%)
Query: 748 QAPAPVPQQPP--PPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQV 805
Q AP+ ++ P PPP++ P PPP++ P PPP A + SPPP
Sbjct: 429 QLEAPLNEEMPLLPPPEESPLSPPPEES--PTSPPP---------EASRLSPPP------ 471
Query: 806 PVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLP-QPPEHSTPPHLNQHAVVSPPALHN 864
+LP S H ++P+ P P P PP S+P + + +SPP
Sbjct: 472 ----EELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPP---- 523
Query: 865 ALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQP---PMAQPPQVLL----EDEE 917
+ P P+ PP A P +SP ++PL P P P + PP+ +E
Sbjct: 524 --EESPPSPALETPLSPPPEASP--LSPPFEESPLSPPPEELPTSPPPEASRLSPPPEES 579
Query: 918 PPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPP---PLPPPPHPSVQQQLQQQP 974
P +PP M + ++ PP P PPP PL PPP S + P
Sbjct: 580 PMSPPPEESPMS-PPPEASRLFPPFEESP-----LSPPPEESPLSPPPEAS-----RLSP 628
Query: 975 PPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPP------PPQGQQPPHPPP--GQ 1026
PP P PP + PPP L P+ + + PP PP + P PPP +
Sbjct: 629 PPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASR 688
Query: 1027 QPPPPQ--PAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSP 1084
PPP+ P P P D + L E+P + PQ+ H SP
Sbjct: 689 LSPPPEDSPTSPPPEDSPASPP---PEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSP 745
Query: 1085 ----PQQNVQPKKQELRAASV---VQPQP----LVVVKEEKIHSPIIRSEPFSPSLRPEP 1133
P + +P++ L + + PQP L V EE P + + P L P+P
Sbjct: 746 RPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEE----PHLSPQAEGPHLSPQP 801
Query: 1134 ------PKHPESIKAPVHLPQRPEMKP--------VDVGRPVIRP-PEQN------APPP 1172
P+ E +PV P+ P + P P + P PE++ PP
Sbjct: 802 EELHLSPQTEEPHLSPV--PEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPP 859
Query: 1173 GAPDKDKQKQEPKTPVAPKK 1192
+P +K +EP AP++
Sbjct: 860 LSPRPEKPPEEPGQCPAPEE 879
Score = 100 bits (248), Expect = 1e-20
Identities = 121/466 (25%), Positives = 160/466 (34%), Gaps = 48/466 (10%)
Query: 739 HHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPP 798
H H Q Q V +Q P + PP P P P A + P
Sbjct: 347 HRCHKAQGGQTIRSVAEQHTPVCSRFSPPEPGDT---------PTDEPDALYVACQGQPK 397
Query: 799 PFIATQVPVLEP---QLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHA 855
T + EP Q G +P L P E P LP P E P +
Sbjct: 398 GGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESP 457
Query: 856 VVSPPALHNALP---QQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVL 912
PP P + P+ P A L +P +SP ++PL P PP + P L
Sbjct: 458 TSPPPEASRLSPPPEELPASPLPEALHL-SRPLEESPLSPPPEESPLSP-PPESSPFSPL 515
Query: 913 LEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPP--LPPPPHPSVQQQL 970
+E P +PP S L +PL P + PPP LP P P
Sbjct: 516 --EESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEAS--- 570
Query: 971 QQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPP 1030
+ PPP P PP + PPP L P F PPP + P P + PP
Sbjct: 571 RLSPPPEESPMSPPPEESPMSPPPEASRLFP-PFEESPLSPPPEESPLSPPPEASRLSPP 629
Query: 1031 PQ--PAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQN 1088
P+ P P SP S P L SPL + S + PP+++
Sbjct: 630 PEDSPMSPPP----EESP---MSPPPEVSRL----SPLPVVSRLSPPPEESPLSPPPEES 678
Query: 1089 VQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQ 1148
E AS + P P E+ SP P SP P + LP+
Sbjct: 679 PTSPPPE---ASRLSPPP-----EDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPE 730
Query: 1149 RPEMKPVDVGRPVIRPPEQN--APPPGAPDKDKQKQEPKTPVAPKK 1192
P++ P G + PE+ +P P P Q +EP P++
Sbjct: 731 EPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEE 776
Score = 87.8 bits (216), Expect = 6e-17
Identities = 138/624 (22%), Positives = 209/624 (33%), Gaps = 110/624 (17%)
Query: 754 PQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLP 813
PQ P P Q P P +P P PP+ P +P + PP + P
Sbjct: 2165 PQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGAS------SRP 2218
Query: 814 GSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHN-ALPQQPSR 872
G+ G F H P P H P P+ P P+L N A+P+ P
Sbjct: 2219 GA--GQPGEF-----HTTPPGTPRHQPSTPDPFLKPRC--------PSLDNLAVPESPGV 2263
Query: 873 PSNRAA--ALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQ- 929
+A+ L P P + + + L P PP + D L ++++
Sbjct: 2264 GGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKT 2323
Query: 930 ---LYLQQLQKVQPPTPLLPSVKVQSQPPPPL-----PPPPHPSV-----QQQLQQQPPP 976
+ P P + ++ Q PPP PP HP + QPP
Sbjct: 2324 PDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPL 2383
Query: 977 PPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKP 1036
P PQP PPP+ PPR + P + P PQ Q Q P P+P
Sbjct: 2384 TPRPQP-PPPESCCALPPRSLPSDPFS-----RVPASPQSQS-----SSQSPLTPRPLSA 2432
Query: 1037 QQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQEL 1096
+ +PR DPYS PS PQ + H+ P QP +
Sbjct: 2433 EAFCPSPVTPRFQSPDPYS-----RPPS-----RPQSRDPFAPLHKPP---RPQPPEVAF 2479
Query: 1097 RAASVVQ--------PQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAP----- 1143
+A S+ P L ++H+ + +P P +++P
Sbjct: 2480 KAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQP------------PNFVRSPGTGAF 2527
Query: 1144 VHLPQRPEMK-PVDVGRPVIRP--PEQNAPPP-------GAPDKDKQKQEPKTPVA---- 1189
V P P VG P ++P P+ PPP G + Q VA
Sbjct: 2528 VGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNF 2587
Query: 1190 -PKKDLKIKNMGSWASLVQKHPTTPSST--AKSSSDSFEQFRRAAREKEEREKALKAQAE 1246
P + GS P P S + S A ++ ++ + +
Sbjct: 2588 HPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKRED 2647
Query: 1247 HAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQE------QQQQQRQEQQQQQQQQ 1300
L + +D ++ E+ R+RQ +QQ QR +Q+++
Sbjct: 2648 PGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETA 2707
Query: 1301 AAAVAAAATPQAQSSQPQSMLDQQ 1324
AAA A P + ++P S +Q
Sbjct: 2708 AAAAGAVGPPGSWGAEPSSPAFEQ 2731
Score = 86.7 bits (213), Expect = 1e-16
Identities = 212/1058 (20%), Positives = 346/1058 (32%), Gaps = 256/1058 (24%)
Query: 163 ELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATP 222
+ PT+E + + V +G+ +G T Q +P P +A P
Sbjct: 379 DTPTDEPDALYVACQGQPKGGHVTSM--------------------QPKEPGPLQCEAKP 418
Query: 223 HPFPAVTPDLIVQTPVMTVVP--PQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQ 280
V + ++ P+ +P P P ++P PP+ + P +P P+ + PP
Sbjct: 419 LGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPE-ESPTSPPPEASRLSPPPEELPAS 477
Query: 281 PVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQ 340
P+ + R P+ E P PP ++ P+ PP + P S
Sbjct: 478 PLPEALHLSR-----------PLEESPLSPPPEES-----------PLSPPPESSPFS-- 513
Query: 341 HPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDM 400
P E E+ + + A+ P P + L P ++
Sbjct: 514 -PLEESPLSPPEESPPSPALETPLSPPPEAS---PLSPPFEESPLS--------PPPEEL 561
Query: 401 STIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFE-MRFAKMPD 459
T +R +E PP+ ++ + +F + +
Sbjct: 562 PTSPPPEASRLSPPPEESPMSP-----------PPEESPMSPPPEASRLFPPFEESPLSP 610
Query: 460 EPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLK 519
PEE SP PPP P DS + + E R L +
Sbjct: 611 PPEE------SPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSR--- 661
Query: 520 AVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSS 579
LS P + P EE+ S PPP+ ++ +
Sbjct: 662 --------LSPPPEESPLSPPP----------------EESPTS----PPPEASRLSPPP 693
Query: 580 NSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSL-DINKLPGEKLGRVVHIIQ 638
+ + P + PPP ED + EE L L + +L G H+
Sbjct: 694 EDSPTSPPPEDSPASPPP------EDSLMSLPLEESPLLPLPEEPQLCPRSEG--PHLSP 745
Query: 639 SREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKK--RKPQAEKVDVIAGSSKMK 696
E + P+E + + +P + E + ++ PQAE + ++
Sbjct: 746 RPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELH 805
Query: 697 GFSSSESESSS---ESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPV 753
+E S E + E+ ++P+S++ P + H ++++ P+
Sbjct: 806 LSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEE---PCLSPRPEESHLSPELEK--PPL 860
Query: 754 PQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLP 813
+P PP++P P P++ PPP P P PA+ P ++ L +LP
Sbjct: 861 SPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSP----LPEELP 916
Query: 814 GSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRP 873
P G +P L P L PP+ PP +PPAL + L +
Sbjct: 917 ---LSPSG----------EPSLSPQL-MPPDPLPPPLSPIITAAAPPAL-SPLGELEYPF 961
Query: 874 SNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQ 933
+ + P P P + +TP+ P PP+ D E P PP+
Sbjct: 962 GAKGDSDPESPLAAP-----ILETPISP------PPEANCTDPE-PVPPM---------- 999
Query: 934 QLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPP 993
+ PP+P P PLPP P +Q L P PP Q PP P
Sbjct: 1000 ----ILPPSPGSPVGPASPILMEPLPPQCSPLLQHSL--VPQNSPPSQCSPPALPLSVPS 1053
Query: 994 PRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQ-PAKPQQVIQHHHSPRHHKSD 1052
P L P+ + + H ++ P+ PA SP S
Sbjct: 1054 P----LSPIGKVVGVSD------EAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSC 1103
Query: 1053 PYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKE 1112
P APSP +P + F L + P +
Sbjct: 1104 P--------APSP----APALDDFSGLGEDTAPLDGID---------------------- 1129
Query: 1113 EKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAP-- 1170
+P +PEP + P S+ + E+K G PV+ PE+ AP
Sbjct: 1130 -------------APGSQPEPGQTPGSLAS--------ELK----GSPVLLDPEELAPVT 1164
Query: 1171 ----------PPGAPDKDKQKQEPKTPVAPKKDLKIKN 1198
G ++++EP+ PVAP IK+
Sbjct: 1165 PMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKS 1202
Score = 74.3 bits (181), Expect = 7e-13
Identities = 99/457 (21%), Positives = 180/457 (39%), Gaps = 72/457 (15%)
Query: 921 PPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPP 980
P + +++L +Q K+Q L V+ Q + L QQQ QQQ
Sbjct: 3557 PEADAEKLKLVTEQQSKIQKQ---LDQVRKQQKEHTNLMAEYRNKQQQQQQQQ------- 3606
Query: 981 QPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPP----PPQGQQPPHPPPGQQPP------- 1029
QQQ Q + L P Q + + P P G QPP PPG Q
Sbjct: 3607 ------QQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPG 3660
Query: 1030 ----PPQPAKP-------QQVIQHHHSPRHHKSDP---YSTGHLRE---APSPLMIHSPQ 1072
P QP P QQ Q H + P + G+L P ++ Q
Sbjct: 3661 GMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQ 3720
Query: 1073 MS---QFQSLTHQSPPQQNVQPKKQELRAASVVQPQP----------LVVVKEEKIHSPI 1119
+ Q L + QQ Q ++Q L +Q Q + K + + P
Sbjct: 3721 LQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPS 3780
Query: 1120 IRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVG-----RPVIRPPEQNAPPPGA 1174
L P+PP+ P+ + P + + P +G R V+ + P
Sbjct: 3781 SHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQL 3840
Query: 1175 PDKDKQKQEPKTPVAPKKDLKIKNM--GSWASL--VQKHPTTPSSTAKSSSDSFEQFRRA 1230
+ + + A ++ + ++ GS A L +Q+ + S K S+ ++
Sbjct: 3841 AQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQL 3900
Query: 1231 AREKE-EREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAH-----EEARRRQE 1284
++++ ++++ L+ Q + +++++L+Q++++ ++ + L+Q ++ ++ +++Q+
Sbjct: 3901 QQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQ 3960
Query: 1285 QQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSML 1321
QQQQQ Q+QQQQQQ + Q Q Q L
Sbjct: 3961 QQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVAL 3997
Score = 66.2 bits (160), Expect = 2e-10
Identities = 79/354 (22%), Positives = 119/354 (33%), Gaps = 61/354 (17%)
Query: 917 EPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPP 976
+P +TSMQ + P PL K + L P + +++ PPP
Sbjct: 395 QPKGGHVTSMQPK----------EPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPP 444
Query: 977 PPPPQPQPPPQQQHQPPPRPVHL---------QPMQFSTHIQQP------PPPQGQQPPH 1021
P PP + PPP L P+ + H+ +P PP + P
Sbjct: 445 EESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLS 504
Query: 1022 PPPGQQP---------PPPQPAKPQQVIQHHHSPRHHK---SDPYSTGHLREAPSPLMIH 1069
PPP P PP+ + P ++ SP S P+ L P L
Sbjct: 505 PPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTS 564
Query: 1070 SP-------------QMSQFQSLTHQSPPQQ--NVQPKKQELRAASVVQPQPLVVVKEEK 1114
P MS + SPP + + P +E + + PL E
Sbjct: 565 PPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEAS 624
Query: 1115 IHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQN--APPP 1172
SP P SP P P + LP + P P+ PPE++ +PPP
Sbjct: 625 RLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPP 684
Query: 1173 GA-----PDKDKQKQEP--KTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKS 1219
A P +D P +P +P + + ++ S + P P +S
Sbjct: 685 EASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRS 738
Score = 58.2 bits (139), Expect = 5e-08
Identities = 106/436 (24%), Positives = 144/436 (33%), Gaps = 94/436 (21%)
Query: 763 QPPPPPPPQQQQQPPPPPPPPSMPQQ---------AAPAMKSSPPPFIATQVPVLEPQLP 813
QP P P P Q PP P QQ + S A+ VP L Q
Sbjct: 4079 QPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPS 4138
Query: 814 GSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRP 873
S+ D G TQ +L Q P L +P +++T P P +P
Sbjct: 4139 VSLGDQPGSMTQNLLGPQQ----PMLERPMQNNTGPQ----------------PPKPGPV 4178
Query: 874 SNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQ 933
LP + P + Q Q +A+ PQ L L ++ MQ LQ
Sbjct: 4179 LQSGQGLP-----GVGIMPTVGQLRAQLQGVLAKNPQ-LRHLSPQQQQQLQALLMQRQLQ 4232
Query: 934 QLQKVQPPTPLLPSVKVQSQP-------PPPLP--PPPHPSVQQQLQQQPPPPPPPQ-PQ 983
Q Q V+ TP Q+ P P L P P Q+L P P PP+ P
Sbjct: 4233 QSQAVR-QTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPA 4291
Query: 984 PPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHH 1043
PP P PVH PPP Q+P P Q P P P +
Sbjct: 4292 PPGALSTGPVLGPVH----------PTPPPSSPQEPKRP---SQLPSPSSQLPTEA---- 4334
Query: 1044 HSPRHHKSDPYSTGHLREAP----SPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAA 1099
P H P G E P SP + L PP + +K E
Sbjct: 4335 QLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPE---- 4390
Query: 1100 SVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGR 1159
LV ++++ ++ PE+ + + + Q P +P +G
Sbjct: 4391 ----QSSLVPGHLDQVNGQVV----------------PEA--SQLSIKQEPREEPCALGA 4428
Query: 1160 PVIRPPEQNAPPPGAP 1175
++ E N P GAP
Sbjct: 4429 QSVK-REANGEPIGAP 4443
Score = 53.1 bits (126), Expect = 2e-06
Identities = 115/514 (22%), Positives = 171/514 (33%), Gaps = 84/514 (16%)
Query: 674 CLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETE--MAPKSKKKGHP 731
C +++ +A + A + K+K + +S+ + + E MA K+
Sbjct: 3543 CAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQ 3602
Query: 732 GREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAP 791
++Q++ H + +P+ P+ P Q P Q Q PP
Sbjct: 3603 QQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGM 3662
Query: 792 AMKSSPP-PFIATQVPVLEPQL----PGSVFDPIGHF-----------------TQPILH 829
A+ P PF+ T + + Q GS+ P G F + L
Sbjct: 3663 ALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQ 3722
Query: 830 LPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPA 889
L Q + L Q + Q ++ A+ Q P +N+A P+ PP+
Sbjct: 3723 LQQQRM--QLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPS 3780
Query: 890 VSPALTQTPLLPQPP-----MAQPPQV-LLEDEEP----PAPP----------------- 922
L L PQPP M P QV +L+ + P P P
Sbjct: 3781 SHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQL 3840
Query: 923 -----------LTSMQMQLYLQQLQKVQPPTPL--LPSVKVQSQPPPPLPPPPHPSVQQQ 969
L + Q Q QQ Q+ L L + P L P S+QQ
Sbjct: 3841 AQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQL 3900
Query: 970 LQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPP 1029
QQQ Q Q QQQ Q + LQ Q QQ Q QQ QQ
Sbjct: 3901 QQQQ----QLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQ 3956
Query: 1030 PPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNV 1089
Q + QQ Q + G L ++ + L SPQ Q Q + P
Sbjct: 3957 QQQQQQQQQFQQQQQQQQ--------MGLLNQSRTLL---SPQQQQQQQVA--LGPGMPA 4003
Query: 1090 QPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSE 1123
+P Q + + P L+ KE+ P + SE
Sbjct: 4004 KP-LQHFSSPGALGPTLLLTGKEQNTVDPAVSSE 4036
Score = 50.4 bits (119), Expect = 1e-05
Identities = 84/390 (21%), Positives = 140/390 (35%), Gaps = 38/390 (9%)
Query: 944 LLPSVKVQSQPPPPLPPPPHPSVQQQLQQQP----PPPPPPQPQPPPQQQHQPPPRPVHL 999
LL K + Q L P+ QQQ QQQ P P Q P + P
Sbjct: 3252 LLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQ 3311
Query: 1000 QPMQFSTHIQQPPPPQGQQPPHPPPG--QQPPPPQPAKPQQ---VIQHHHS------PRH 1048
Q +QP PQ P PP QQ P A ++ H P+
Sbjct: 3312 QLSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQ 3371
Query: 1049 HKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLV 1108
S + P + + Q++ Q L + P ++ + A ++ P
Sbjct: 3372 SSQPVLSQKPMGTMPPSMCMKPQQLAMQQQLANSFFPDTDLD----KFAAEDIIDP---- 3423
Query: 1109 VVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPV-DVGRPVIRPP-- 1165
+ K + + I+ S+ P + + + L QR P D+ V
Sbjct: 3424 IAKAKMVALKGIKKVMAQGSIGVAPGMNRQQVSL---LAQRLSGGPSSDLQNHVAAGSGQ 3480
Query: 1166 EQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFE 1225
E++A P P + P + + W Q+ +
Sbjct: 3481 ERSAGDPSQP----RPNPPTFAQGVINEADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHR 3536
Query: 1226 QFRRAAREKEEREKALKAQAEHAEKEKERLR---QERMRSREDEDALEQARRAHEEARRR 1282
+ R+A K+ K KA E E + E+L+ +++ + ++ D + + ++ H
Sbjct: 3537 KSRKALCAKQRTAK--KAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAE 3594
Query: 1283 QEQQQQQRQEQQQQQQQQAAAVAAAATPQA 1312
+QQQ+Q+QQQQQQQQ +AV A + Q+
Sbjct: 3595 YRNKQQQQQQQQQQQQQQHSAVLALSPSQS 3624
Score = 47.4 bits (111), Expect = 1e-04
Identities = 124/560 (22%), Positives = 187/560 (33%), Gaps = 72/560 (12%)
Query: 676 RKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQ 735
+++++ Q ++ +AG S ++ S S S S+ S ++ + + + +Q
Sbjct: 3857 QQQQQQQHQQQGSMAGLSHLQ--QSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQ 3914
Query: 736 KKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKS 795
++ QQ Q QQ QQ QQQQQ QQ +
Sbjct: 3915 QQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQ--QQQQQFQQQQQQ 3972
Query: 796 SPPPFIATQVPVLEPQL---------PGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHS 846
+ +L PQ PG P+ HF+ P L P L +
Sbjct: 3973 QQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSP------GALGPTLLLTGKE- 4025
Query: 847 TPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMA 906
Q+ V PA+ + + PS A+ P ++ P +P ++
Sbjct: 4026 ------QNTV--DPAVSSEATEGPSTHQGGPLAIGTTPE-------SMATEPGEVKPSLS 4070
Query: 907 QPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSV 966
Q+LL +P P +S+Q+Q L+ + Q LL + S S
Sbjct: 4071 GDSQLLLVQPQPQPQP-SSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASS 4129
Query: 967 QQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQ 1026
L QP QP Q P +P+ +PMQ +T Q P P Q PG
Sbjct: 4130 VPHLLAQPSVSLGDQPGSMTQNL-LGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGV 4188
Query: 1027 QPPPPQP---AKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQS 1083
P A+ Q V+ + RH S ++ + LM Q SQ Q+
Sbjct: 4189 GIMPTVGQLRAQLQGVLAKNPQLRH-----LSPQQQQQLQALLMQRQLQQSQ---AVRQT 4240
Query: 1084 PPQQNVQPKKQELRAASVVQPQ------PLVVVKEEKIHSPIIRSEPFSPS--------- 1128
PP Q + L+ QPQ P +E P + P P+
Sbjct: 4241 PPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGP 4300
Query: 1129 -LRP----EPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQE 1183
L P PP P+ K P LP P + P P P P P +
Sbjct: 4301 VLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLP---PTHPGTPKPQGPTLEPPPGR 4357
Query: 1184 PKTPVAPKKD-LKIKNMGSW 1202
A D L K +G W
Sbjct: 4358 VSPAAAQLADTLFSKGLGPW 4377
Score = 45.1 bits (105), Expect = 5e-04
Identities = 76/301 (25%), Positives = 113/301 (37%), Gaps = 29/301 (9%)
Query: 205 PPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPA 264
PP P P+ P P P V + Q P + P PL+ P P P PP P+
Sbjct: 2145 PPAGSVPGPDSPGELFLKLP-PQVPAQVPSQDP-FGLAPAYPLEPRFPTAP-PTYPPYPS 2201
Query: 265 PQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPP--EPKTTKLGQRR 322
P + PP++ A+ +P + G + TT P T P H+P + P +P+ L
Sbjct: 2202 PTGAPAQPPMLGASSRPGAGQPG---EFHTTPPGT--PRHQPSTPDPFLKPRCPSLDNLA 2256
Query: 323 ESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDV 382
P K + P P S+ + ++K KE +Y P VD
Sbjct: 2257 VPESPGVGGGK-ASEPLLSPPPFGESRKALEVK------KEELGASSPSYGPPNLGFVDS 2309
Query: 383 EALGLHDYCDIIKHPMDMSTIKSKLEAREYR-DAQEFGADVRLMF---SNCYKYNPPDHE 438
+ G H +K P K+ L R + + Q G +R + +PP H
Sbjct: 2310 PSSGTHLGGLELKTP---DVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHP 2366
Query: 439 VVAMARKLQDVFEMRFAKMPDEPE-EPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSD 497
+ D +A+ P P +P S A+PP + P S +S S S S
Sbjct: 2367 DIFRPGSYTD----PYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQ 2422
Query: 498 S 498
S
Sbjct: 2423 S 2423
Score = 44.7 bits (104), Expect = 6e-04
Identities = 55/195 (28%), Positives = 78/195 (40%), Gaps = 29/195 (14%)
Query: 744 QQMQQAPAPV--PQQPPPP----------PQQPPPPPPPQQQQQPPPPPPPPS--MPQQA 789
Q++ P P P+ P PP P P PPP Q+ + P P PS +P +A
Sbjct: 4275 QELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEA 4334
Query: 790 --APAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILH--LPQPELPPHL--PQPP 843
P +P P Q P LEP PG V + L + P +L Q P
Sbjct: 4335 QLPPTHPGTPKP----QGPTLEPP-PGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKP 4389
Query: 844 EHST--PPHLNQ-HAVVSPPALHNALPQQP-SRPSNRAAALPPKPARPPAVSPALTQTPL 899
E S+ P HL+Q + V P A ++ Q+P P A + A + T L
Sbjct: 4390 EQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHL 4449
Query: 900 LPQPPMAQPPQVLLE 914
L P ++ +LL+
Sbjct: 4450 LLAGPRSEAGHLLLQ 4464
Score = 42.7 bits (99), Expect = 0.002
Identities = 26/89 (29%), Positives = 38/89 (42%), Gaps = 17/89 (19%)
Query: 727 KKGHPGREQKKHHHHHHQ----QMQQAPAPVPQQPPPPPQQPPPPP-----------PPQ 771
K+ P E H + + ++Q AP P++P PPP P P P +
Sbjct: 4880 KQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTE 4939
Query: 772 QQQQPPPPPPPP--SMPQQAAPAMKSSPP 798
+PP P P P S P+ A P ++ PP
Sbjct: 4940 PLAEPPVPSPLPLASSPESARPKPRARPP 4968
Score = 42.0 bits (97), Expect = 0.004
Identities = 32/107 (29%), Positives = 42/107 (39%), Gaps = 21/107 (19%)
Query: 762 QQPPPPPPPQQ-------------QQQPPPP--PPPPSMPQQAAPAMKSSPPPFIATQVP 806
Q+ P P PP Q Q PPP P PP P +PA + P P
Sbjct: 4881 QESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEP 4940
Query: 807 VLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQ 853
+ EP +P P+ + P P+P P P+ E S PP L +
Sbjct: 4941 LAEPPVP----SPLPLASSPESARPKPRARP--PEEGEDSRPPRLKK 4981
Score = 41.6 bits (96), Expect = 0.005
Identities = 30/115 (26%), Positives = 43/115 (37%), Gaps = 7/115 (6%)
Query: 931 YLQQLQKVQPPTPLLPSVKVQS----QPPPPLPPPPHP---SVQQQLQQQPPPPPPPQPQ 983
+L+Q V P L + + S + P P PP H +V +Q PPP +P
Sbjct: 4856 WLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPS 4915
Query: 984 PPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQ 1038
PPP P P ++ T PP P P P P+ P++
Sbjct: 4916 PPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEE 4970
Score = 38.9 bits (89), Expect = 0.034
Identities = 42/176 (23%), Positives = 61/176 (34%), Gaps = 24/176 (13%)
Query: 859 PPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEP 918
P + P+ P+R +P + A P + L + P P + D
Sbjct: 4812 PNSYEVLFPESPARAGT-------EPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVL 4864
Query: 919 PAPPLTSMQMQLYLQQLQKVQPPTPLLPS------------VKVQSQPPPPLPPPPHPSV 966
P L S QL + L K + P P P+ V+ S PPP P PP +
Sbjct: 4865 PGYTLKS---QLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPL 4921
Query: 967 QQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQ--QPP 1020
P P P P + P P P+ P + PP +G+ +PP
Sbjct: 4922 APSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPP 4977
Score = 38.5 bits (88), Expect = 0.044
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 5/81 (6%)
Query: 215 PPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQP--QPPPAPAPQPVQSHP 272
PPP + +P P P T + +P +PL PP P P P + P+P ++ P
Sbjct: 4909 PPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKP-RARP 4967
Query: 273 PIIAATPQPVKTK--KGVKRK 291
P +P + K KGV+ K
Sbjct: 4968 PEEGEDSRPPRLKKWKGVRWK 4988
Score = 37.7 bits (86), Expect = 0.076
Identities = 53/227 (23%), Positives = 79/227 (34%), Gaps = 21/227 (9%)
Query: 750 PAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPP----SMPQQAAPAMKSSPPPFIATQV 805
P PVP PP P P +P PP P S+ Q +P + SPP +
Sbjct: 993 PEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPP-----AL 1047
Query: 806 PVLEPQLPGSVFDPIGHFTQPILHLPQPE--LPPHLPQPPEHSTPPHLNQHAVVSPPALH 863
P+ P + +G + LH + E P P +T P + +S PA
Sbjct: 1048 PLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPS 1107
Query: 864 NALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPL 923
A P P P P QTP + P +L +E P P
Sbjct: 1108 PA-PALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTP- 1165
Query: 924 TSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQL 970
M++Y + Q +P + Q +P P+ P P ++ +
Sbjct: 1166 ----MEVYPECKQTAGQGSP----CEEQEEPRAPVAPTPPTLIKSDI 1204
Score = 37.7 bits (86), Expect = 0.076
Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 30/113 (26%)
Query: 190 KPGVSTVPNTTQASTPPQTQTPQPNPP------PVQATPH-PFPAVTPDLIVQTPVMTVV 242
+PG T P + PP T PQP PP P ++ P PF V Q+ + +
Sbjct: 2370 RPGSYTDPY----AQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPL 2425
Query: 243 PPQPL--------------QTP-----PPVPPQPQPPPAPAPQPVQSHPPIIA 276
P+PL Q+P PP PQ + P AP +P + PP +A
Sbjct: 2426 TPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVA 2478
Score = 37.7 bits (86), Expect = 0.076
Identities = 50/219 (22%), Positives = 67/219 (30%), Gaps = 31/219 (14%)
Query: 859 PPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEP 918
P L + S PS+ + PP PA P ++ Q Q + P P
Sbjct: 2753 PSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPY-------P 2805
Query: 919 PAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPP 978
+ PL Q QL+ QQ S + S P P L S + + P P
Sbjct: 2806 GSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPG 2865
Query: 979 PPQPQPPPQQQH--------------------QPPPRPVHLQPMQFSTHIQQPPPPQGQQ 1018
P P P Q Q PP+ P+ H P +G
Sbjct: 2866 EPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLA 2925
Query: 1019 PPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTG 1057
PP + PP P ++ H H K TG
Sbjct: 2926 VSGLPPQKPSAPPAP----ELNNSLHPTPHTKGPTLPTG 2960
Score = 37.0 bits (84), Expect = 0.13
Identities = 31/101 (30%), Positives = 41/101 (40%), Gaps = 17/101 (16%)
Query: 912 LLEDEEP-PAPPL----TSMQMQLYLQQL------QKVQPPTPLLPSVK------VQSQP 954
LL+ E P P PP T L ++QL + PP+PL PS + P
Sbjct: 4878 LLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELP 4937
Query: 955 PPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPR 995
PL PP PS P P+ +PP + + PPR
Sbjct: 4938 TEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPR 4978
Score = 36.2 bits (82), Expect = 0.22
Identities = 67/278 (24%), Positives = 100/278 (35%), Gaps = 38/278 (13%)
Query: 940 PPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHL 999
PP P++ + S P P S L+ PP P P P + + PP+
Sbjct: 2116 PPPAAAPTIFIGS---PTTPAGLSTSADGFLK--PPAGSVPGPDSPGELFLKLPPQVPAQ 2170
Query: 1000 QPMQFSTHIQQPPPPQGQQPPHPP--PGQQPPPPQPAKPQQVIQHH-----HSPRHHKSD 1052
P Q + P + + P PP P P PA+P + H +
Sbjct: 2171 VPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTP 2230
Query: 1053 PYSTGHLREAPSPLMIHSPQMSQFQSL-THQSPPQQNVQPKKQELRAASVVQPQPLVVVK 1111
P + H P P + P+ +L +SP + + L + + + VK
Sbjct: 2231 PGTPRHQPSTPDPFL--KPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVK 2288
Query: 1112 EEKI--HSP--------IIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVG--- 1158
+E++ SP + S L K P+ KAP+ P+ +++P G
Sbjct: 2289 KEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPL-TPRASQVEPQSPGLGL 2347
Query: 1159 RPVIRPPEQN-AP-PPGAPD-------KDKQKQEPKTP 1187
RP PP Q AP PP PD D Q P TP
Sbjct: 2348 RPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTP 2385
Score = 36.2 bits (82), Expect = 0.22
Identities = 20/59 (33%), Positives = 23/59 (38%)
Query: 203 STPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPP 261
ST P P PPP P+ P Q P +PP TP P P +PPP
Sbjct: 4297 STGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPP 4355
Score = 34.7 bits (78), Expect = 0.64
Identities = 47/168 (27%), Positives = 63/168 (37%), Gaps = 43/168 (25%)
Query: 769 PPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPV--LEPQLPGSVFD---PIGHF 823
P QQQQQ QQ ++ S+P P A +P P L GS +
Sbjct: 3272 PAQQQQQ-----------QQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGA 3320
Query: 824 TQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPK 883
QP LPQP +P QPP H AL L + SN+ L +
Sbjct: 3321 RQP--GLPQPLMPT---QPPAH---------------ALQQRLAPSMAMVSNQGHMLSGQ 3360
Query: 884 PARPPAVSPALTQTPLLPQPPM-AQPPQVLLEDEEPPAPPLTSMQMQL 930
+ P + P+L Q PM PP + ++ P +MQ QL
Sbjct: 3361 HGGQAGLVPQQSSQPVLSQKPMGTMPPSMCMK------PQQLAMQQQL 3402
Score = 34.7 bits (78), Expect = 0.64
Identities = 30/124 (24%), Positives = 48/124 (38%), Gaps = 24/124 (19%)
Query: 209 QTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPV 268
++P P PP T H + +L V+ PP +PPP P P P P
Sbjct: 4882 ESPAPEPP----TQHSYTYNVSNLDVR---QLSAPPPEEPSPPPSPLAPSPASPPT---- 4930
Query: 269 QSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPV 328
P++ +P+ A+ P+ + P S P+P+ + + E SRP
Sbjct: 4931 ---EPLVELPTEPL---------AEPPVPSPLPLASSPESARPKPR-ARPPEEGEDSRPP 4977
Query: 329 KPPK 332
+ K
Sbjct: 4978 RLKK 4981
Score = 33.9 bits (76), Expect = 1.1
Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 8/68 (11%)
Query: 1266 EDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQ-----SM 1320
ED LE ++ E +++Q+ Q + QQQQQQQQ ++ +A P S P S+
Sbjct: 3250 EDLLEHEKK---ELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSL 3306
Query: 1321 LDQQRELA 1328
Q++L+
Sbjct: 3307 AGSQQQLS 3314
Score = 32.3 bits (72), Expect = 3.2
Identities = 44/182 (24%), Positives = 60/182 (32%), Gaps = 33/182 (18%)
Query: 191 PGVSTVPNTTQASTP-PQTQTPQPNPP----------PVQATPHPFPAVTPDLIVQTPVM 239
PG T P + P PQ P PP PV TP P P Q P
Sbjct: 4267 PGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSP 4326
Query: 240 TVVPPQPLQTPPPVP--PQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTP 297
+ P Q PP P P+PQ P P P + + ADT
Sbjct: 4327 SSQLPTEAQLPPTHPGTPKPQGP---------------TLEPPPGRVSPAAAQLADTLFS 4371
Query: 298 TTIDPIHEPPSL----PPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQ 353
+ P P +L PE + G + + V P + +Q P E + ++
Sbjct: 4372 KGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQL-SIKQEPREEPCALGAQS 4430
Query: 354 LK 355
+K
Sbjct: 4431 VK 4432
Score = 32.0 bits (71), Expect = 4.2
Identities = 36/168 (21%), Positives = 54/168 (32%), Gaps = 17/168 (10%)
Query: 993 PPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSD 1052
P P + + ++ PP P PP PPP Q P + + H
Sbjct: 4601 PTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEH--------- 4651
Query: 1053 PYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAAS------VVQPQP 1106
P R++ L S S +PP + + E S V P
Sbjct: 4652 PKDAASARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSP 4711
Query: 1107 LVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKP 1154
++ EE P + S + R P P +A + P P+ KP
Sbjct: 4712 ESILGEEAPRFPHLGSGRWEQEDRALSPVIPLIPRASI--PVFPDTKP 4757
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 125 bits (315), Expect = 2e-28
Identities = 133/464 (28%), Positives = 169/464 (36%), Gaps = 81/464 (17%)
Query: 705 SSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPP----P 760
SS+++ + D E+ +G P + K Q +P PQ PPP
Sbjct: 14 SSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNK------PQGPPSPPGKPQGPPPQGGNQ 67
Query: 761 PQQPPPPP-----PPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGS 815
PQ PPPPP PP Q P PPPP PQ P S P + P +PQ P
Sbjct: 68 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSP----RSPPGKPQGP-- 121
Query: 816 VFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSN 875
P QP+ PP P P+ P N+ PP P Q S
Sbjct: 122 ----------PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSR 171
Query: 876 RAAALPPKPARPPAVSPALTQ-TPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQ 934
+ + P KP PP Q P P P PPQ + + PP P
Sbjct: 172 SSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP------------- 218
Query: 935 LQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQ-----Q 989
K Q P P + ++ PP P P P Q Q Q PPPPP +PQ PP Q Q
Sbjct: 219 -GKPQGPPPQGDNKSQSARSPPGKPQGPPP--QGGNQPQGPPPPPGKPQGPPPQGGNKPQ 275
Query: 990 HQPPP-RPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQP--PPPQPAKPQQVIQHHHSP 1046
PPP +P P S PP Q P P G QP PPP P KPQ
Sbjct: 276 GPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ--------- 326
Query: 1047 RHHKSDPYSTGHLREAPSP--LMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQP 1104
P G+ + P P P +S + +SPP + P +QE + P
Sbjct: 327 ----GPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQE--GNNPQGP 380
Query: 1105 QPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQ 1148
P ++ +P P+ +P+ P P P PQ
Sbjct: 381 PPPAGGNPQQPQAP--------PAGQPQGPPRPPQGGRPSRPPQ 416
Score = 95.1 bits (235), Expect = 4e-19
Identities = 119/442 (26%), Positives = 141/442 (31%), Gaps = 124/442 (28%)
Query: 765 PPPPPPQQQQQPPPPPPPPSMPQQAAPA---MKSSPPPFIATQVPVLEPQLPGSVFDPIG 821
P PPQ +P PP PP PQ P PPP P +PQ P P G
Sbjct: 36 PQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPP------PPGKPQGP----PPQG 85
Query: 822 HFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALP 881
+ PQ PP PQ P PP ++ P P +P P + P
Sbjct: 86 G------NKPQGPPPPGKPQGP----PPQGDKSRSPRSP------PGKPQGPPPQGGNQP 129
Query: 882 PKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPP 941
P PP P PPQ + + PP P K Q P
Sbjct: 130 QGPPPPPG-------------KPQGPPPQGGNKPQGPPPPG--------------KPQGP 162
Query: 942 TPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQ-----QHQPPPRP 996
P + S+ PP P P P Q Q Q PPPPP +PQ PP Q Q PPP
Sbjct: 163 PPQGDNKSRSSRSPPGKPQGPPP--QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 220
Query: 997 VHLQPMQFSTHIQQPPPPQGQQPPHPPP--GQQP--PPPQPAKPQQVIQHHHSPRHHKSD 1052
P Q Q P G+ P PPP G QP PPP P KPQ
Sbjct: 221 PQGPPPQGDNKSQSARSPPGK-PQGPPPQGGNQPQGPPPPPGKPQ-------------GP 266
Query: 1053 PYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKE 1112
P G+ + P P Q PP Q +
Sbjct: 267 PPQGGNKPQGPPP------------PGKPQGPPPQGGSKSRSS----------------- 297
Query: 1113 EKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPP----EQN 1168
RS P P + PP+ + P P +P+ P G PP Q
Sbjct: 298 --------RSPPGKP--QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 347
Query: 1169 APPPGAPDKDKQKQEPKTPVAP 1190
PP G + P P P
Sbjct: 348 PPPQGGSKSRSARSPPGKPQGP 369
Score = 84.0 bits (206), Expect = 9e-16
Identities = 86/305 (28%), Positives = 107/305 (35%), Gaps = 41/305 (13%)
Query: 899 LLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPL 958
L+ P PPQ + + PP+PP K Q P P + Q Q PPP
Sbjct: 31 LIAGNPQGAPPQGGNKPQGPPSPP-------------GKPQGPPPQGGN---QPQGPPPP 74
Query: 959 PPPPHPSVQQQLQQQPPPPPPPQPQPPPQQ------QHQPPPRPVHLQPMQFSTHIQQPP 1012
P P Q + PPPP +PQ PP Q PP +P P Q Q PP
Sbjct: 75 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG-PPPQGGNQPQGPP 133
Query: 1013 PPQGQQPPHPPPGQQPP--PPQPAKPQ-QVIQHHHSPRHHKSDPYSTGHLREAPSPLMIH 1069
PP G+ PP G P PP P KPQ Q + R +S P + P P +
Sbjct: 134 PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKP----QGPPPQGGN 189
Query: 1070 SPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSL 1129
PQ Q PP Q + P P K + SP +P P
Sbjct: 190 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSP--PGKPQGP-- 245
Query: 1130 RPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPP----EQNAPPPGAPDKDKQKQEPK 1185
PP+ + P P +P+ P G PP Q PP G + P
Sbjct: 246 ---PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPG 302
Query: 1186 TPVAP 1190
P P
Sbjct: 303 KPQGP 307
Score = 83.6 bits (205), Expect = 1e-15
Identities = 96/365 (26%), Positives = 126/365 (34%), Gaps = 69/365 (18%)
Query: 832 QPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVS 891
+P+ PP P P+ P NQ PP PQ P PP P +P
Sbjct: 46 KPQGPPSPPGKPQGPPPQGGNQPQGPPPPP---GKPQGPPPQGGNKPQGPPPPGKPQGPP 102
Query: 892 PA--LTQTPLLPQ-PPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSV 948
P +++P P P PPQ + + PP PP K Q P P +
Sbjct: 103 PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP-------------GKPQGPPPQGGN- 148
Query: 949 KVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPP-PRPVHLQPMQFSTH 1007
K Q PPP P P P + + PP PQ PPPQ +QP P P +P
Sbjct: 149 KPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQG-PPPQGGNQPQGPPPPPGKP------ 201
Query: 1008 IQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLM 1067
Q PPP G +P PPP +P P P + P + P G+ + P P
Sbjct: 202 -QGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPP-- 258
Query: 1068 IHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSP 1127
P Q PPQ +P+ P P +P P
Sbjct: 259 --PPGKPQ------GPPPQGGNKPQGP---------PPP---------------GKPQGP 286
Query: 1128 SLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQK-QEPKT 1186
PP+ ++ P +P+ P G PP P G P + K Q P
Sbjct: 287 -----PPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 341
Query: 1187 PVAPK 1191
P P+
Sbjct: 342 PGKPQ 346
Score = 48.9 bits (115), Expect = 3e-05
Identities = 48/181 (26%), Positives = 65/181 (35%), Gaps = 12/181 (6%)
Query: 178 GRGRGRKETGTAKP-GVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQT 236
G+ +G G +P G P Q P PQ PPP + P ++
Sbjct: 178 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARS 237
Query: 237 PVMTVVPPQPL-----QTPPPVPPQPQ-PPPAPAPQPVQSHPPIIAATPQPVKTKKGVKR 290
P P P Q PPP P +PQ PPP +P PP P P K
Sbjct: 238 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSS 297
Query: 291 KADTTTPTTIDPI--HEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSS 348
++ P P ++P PP P + + ++P PP P Q P P+ S
Sbjct: 298 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP---PGKPQGPPPQGGS 354
Query: 349 K 349
K
Sbjct: 355 K 355
Score = 48.5 bits (114), Expect = 4e-05
Identities = 58/226 (25%), Positives = 79/226 (34%), Gaps = 33/226 (14%)
Query: 146 IVLMAEALEKLF-LQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQAST 204
++L++ AL L Q +NE ++E ++ G +G G KP P
Sbjct: 3 LILLSVALLALSSAQNLNEDVSQEESPSLIA--GNPQGAPPQGGNKPQGPPSPPGKPQGP 60
Query: 205 PPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPP---------VPP 255
PPQ PPP P P + P PP Q PPP PP
Sbjct: 61 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP-----PPGKPQGPPPQGDKSRSPRSPP 115
Query: 256 ------------QPQPPPAPAPQPVQSHPPIIAATPQ---PVKTKKGVKRKADTTTPTTI 300
QPQ PP P +P Q PP PQ P +G + D + ++
Sbjct: 116 GKPQGPPPQGGNQPQGPPPPPGKP-QGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSR 174
Query: 301 DPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEK 346
P +P PP+ G +P PP + Q P P K
Sbjct: 175 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 220
Score = 42.4 bits (98), Expect = 0.003
Identities = 42/168 (25%), Positives = 59/168 (35%), Gaps = 25/168 (14%)
Query: 178 GRGRGRKETGTAKP-GVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQT 236
G+ +G G +P G P Q P PQ PPP + P + ++
Sbjct: 240 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRS 299
Query: 237 PVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTT 296
P P +P PP QPQ PP P +P Q PP PQ
Sbjct: 300 P-----PGKPQGPPPQGGNQPQGPPPPPGKP-QGPPPQGGNKPQGPP------------- 340
Query: 297 PTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAP 344
P +P PP+ + R +P PP+++ + Q P P
Sbjct: 341 -----PPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPP 383
Score = 35.8 bits (81), Expect = 0.29
Identities = 40/166 (24%), Positives = 49/166 (29%), Gaps = 41/166 (24%)
Query: 178 GRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTP 237
G+ +G G +K S P PPQ PPP P P + P
Sbjct: 281 GKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 340
Query: 238 VMTVVPPQPLQTPPPV-----------PPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKK 286
PP Q PPP P +PQ PP Q PP PQ +
Sbjct: 341 -----PPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQA-- 393
Query: 287 GVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPK 332
P P PP P + RP +PP+
Sbjct: 394 ---------------PPAGQPQGPPRPP--------QGGRPSRPPQ 416
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 125 bits (314), Expect = 3e-28
Identities = 217/906 (23%), Positives = 318/906 (35%), Gaps = 183/906 (20%)
Query: 244 PQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPI 303
PQ L P Q PA A P P P P+ T +K TTT P
Sbjct: 375 PQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIK----TTTRQLSSPN 430
Query: 304 HEPPSLP---------PEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQL 354
H P P PEP ++ G R + P KK D +S+ +E+L
Sbjct: 431 HSPSQSPNQSPRIKRRPEPSLSR-GSRTALASVAAPAKKHRADGGLAAGLSRSADWTEEL 489
Query: 355 KCCS---GILKEMFAKKHAAYAWPFYKP-VDVEALGLHDYCDIIKHPMDMSTIKSKLEAR 410
+ G + + A+ + P + +A G D ++ T+ KL ++
Sbjct: 490 GARTPRVGGSAHLLERGVASDSGGGVSPALAAKASGAPAAADGFQNVFTGRTLLEKLFSQ 549
Query: 411 EYR----DAQEFGADVRLM-----FSNCYKYNPPDHEVVAMARKLQD-VFEMRFAKMPDE 460
+ +A++F + + M FS+C++ + A QD ++ P
Sbjct: 550 QENGPPEEAEKFCSRIIAMGLLLPFSDCFREPCNQNAQTNAASFDQDQLYTWAAVSQPTH 609
Query: 461 P---EEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQ-------- 509
E P++ PP+K PP D+ ++S S+ ++ ++R+
Sbjct: 610 SLDYSEGQFPRRVPSMGPPSK---PPDEEHRLEDAETESQSAVSETPQKRSDAVQKEVVD 666
Query: 510 ----------------------RLAELQEQLKAVHEQLAALSQPQQNKPKKK-----EKD 542
++AEL+ Q A+ ++A+ Q +N E
Sbjct: 667 MKSEGQATVIQQLEQTIEDLRTKIAELERQYPALDTEVASGHQGLENGVTASGDVCLEAL 726
Query: 543 KKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESE 602
+ E+K+ +H R E + + S +E + + P + PP ES
Sbjct: 727 RLEEKEVRHHRILEAKSIQTSPTEE----------GGVLTLPPVDGLPGRPPCPPGAESG 776
Query: 603 EEDK-CKPMSY-EEKRQLSLDINK-LPGEKLGRVV---HIIQSREPSLKNSNPDE-IEID 655
+ K C +S R++S+ ++ P + + + ++ S S P I +
Sbjct: 777 PQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTE 836
Query: 656 FETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSE 715
F+T ++ + SC P + SS M G +
Sbjct: 837 FQTSHEHSVSSA--FKNSC----NIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPT 890
Query: 716 DSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQ--PPPPPQQ---------- 763
T + +G + + P P+P PPPPP
Sbjct: 891 LPSTAIPQPPPLQGT-------------EMLPPPPPPLPGAGIPPPPPLPGAGILPLPPL 937
Query: 764 -----PPPPPPPQQQQQPPPPPP------PPSMPQQAAPAMKSSPPPFIATQVPVLEPQL 812
PPPPP P PPPP P PP +P P PPP +P P L
Sbjct: 938 PGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIP----PPPPLPGAGIPP-PPPL 992
Query: 813 PGSVFDP----IGHFTQPILHLPQPELPPHLPQPPEH-STPPHLNQHAVVSPPALHNA-L 866
PG+ P G P LP +PP P P PP L + PP L A +
Sbjct: 993 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1052
Query: 867 PQQPSRPSNRAAALPPKPARPPA---VSPALTQTPLLPQPPM----AQPPQVLLEDEEPP 919
P P P A +PP P P A P L + P PP+ PP L PP
Sbjct: 1053 PPPPPLP---GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP 1109
Query: 920 APPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLP----PPPHPSVQQQLQQQPP 975
PPL + PP P LP + PPPPLP PPP P + + PP
Sbjct: 1110 PPPLPGAGI-----------PPPPPLPGAGI--PPPPPLPGAGIPPPPPLPRVGI---PP 1153
Query: 976 PPPPP----QPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPP----GQQ 1027
PPP P P PP PPP P+ I PPP G P PPP G
Sbjct: 1154 PPPLPGAGIPPPPPLPGAGIPPPPPLP------GVGIPPPPPLPGVGIPPPPPLPGAGIP 1207
Query: 1028 PPPPQP 1033
PPPP P
Sbjct: 1208 PPPPLP 1213
Score = 119 bits (299), Expect = 2e-26
Identities = 108/311 (34%), Positives = 122/311 (39%), Gaps = 67/311 (21%)
Query: 751 APVPQQPPPPPQQPPPPPPPQQQQQPPPP-------PPPPSMPQQAAPAMKSSPPPFIAT 803
A +P PP P PPPPP PPPP PPPP +P P PPP
Sbjct: 962 AGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP----PPPPLPGA 1017
Query: 804 QVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEH-STPPHLNQHAVVSPPAL 862
+P P LPG+ P P LP +PP P P PP L + PP L
Sbjct: 1018 GIPP-PPPLPGAGIPP----PPP---LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1069
Query: 863 HNA-LPQQPSRPSNRAAALPPKPARPPA---VSPALTQTPLLPQPPM----AQPPQVLLE 914
A +P P P A +PP P P A P L + P PP+ PP L
Sbjct: 1070 PGAGIPPPPPLP---GAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPG 1126
Query: 915 DEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLP----PPPHPSVQQQL 970
PP PPL + PP P LP V + PPPPLP PPP P +
Sbjct: 1127 AGIPPPPPLPGAGI-----------PPPPPLPRVGI--PPPPPLPGAGIPPPPPLPGAGI 1173
Query: 971 QQQPPPPPPP----QPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPP------PQGQQPP 1020
PPPPP P P PP PPP P+ I PPP P PP
Sbjct: 1174 ---PPPPPLPGVGIPPPPPLPGVGIPPPPPLP------GAGIPPPPPLPGMGIPPAPAPP 1224
Query: 1021 HPPPGQQPPPP 1031
PPPG PPP
Sbjct: 1225 LPPPGTGIPPP 1235
Score = 119 bits (299), Expect = 2e-26
Identities = 123/403 (30%), Positives = 152/403 (37%), Gaps = 71/403 (17%)
Query: 750 PAPVPQQ--PPPPPQQ----PPPPPPPQQQQQPPPP------PPPPSMPQQAAPAMKSSP 797
P P+P PPPPP PPPPP P PPPP PPPP +P P P
Sbjct: 978 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP----P 1033
Query: 798 PPFIATQVPVLEPQLPGSVFDPI----GHFTQPILHLPQPELPPHLPQPPEH-STPPHLN 852
PP +P P LPG+ P G P LP +PP P P PP L
Sbjct: 1034 PPLPGAGIPP-PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1092
Query: 853 QHAVVSPPALHNA-LPQQPSRPSNRAAALPPKPARPPAVSPALTQTP---LLPQPPMAQ- 907
+ PP L +P P P A +PP P P A P P + P PP+ +
Sbjct: 1093 GAGIPPPPPLPGVGIPPPPPLPG---AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRV 1149
Query: 908 ---PPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLP----P 960
PP L PP PPL + PP P LP V + PPPPLP P
Sbjct: 1150 GIPPPPPLPGAGIPPPPPLPGAGI-----------PPPPPLPGVGI--PPPPPLPGVGIP 1196
Query: 961 PPHPSVQQQLQQQPP------PPPPPQPQPPPQQQHQPPP-RPVHLQPMQFSTHIQQPPP 1013
PP P + PP PP P P PPP PPP PV P+ P
Sbjct: 1197 PPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPT 1256
Query: 1014 PQ--GQQPPHPP-----------PGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLR 1060
PQ G PP P G + P +P +P + + H K D ST +
Sbjct: 1257 PQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRIQLHSKRDS-STSLIW 1315
Query: 1061 EAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQ 1103
E I + + S T ++ + + +A VV+
Sbjct: 1316 EKIEEPSIDCHEFEELFSKTAVKERKKPISDTISKTKAKQVVK 1358
Score = 49.7 bits (117), Expect = 2e-05
Identities = 44/155 (28%), Positives = 55/155 (35%), Gaps = 15/155 (9%)
Query: 192 GVSTVPNTTQASTPPQTQTPQ---PNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQ 248
G+ P A PP P P PPP+ P P P + P PP P
Sbjct: 1084 GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPP-----PPLPGA 1138
Query: 249 TPPPVPPQPQ---PPPAPAP-QPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIH 304
PP PP P+ PPP P P + PP+ A P GV P P
Sbjct: 1139 GIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPP 1198
Query: 305 EP---PSLPPEPKTTKLGQRRESSRPVKPPKKDVP 336
P +PP P +G + P+ PP +P
Sbjct: 1199 PPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIP 1233
Score = 47.0 bits (110), Expect = 1e-04
Identities = 36/131 (27%), Positives = 47/131 (35%), Gaps = 11/131 (8%)
Query: 192 GVSTVPNTTQASTPPQTQTPQ---PNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQP-- 246
G+ P A PP P+ P PPP+ P P P + P PP P
Sbjct: 1128 GIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPP-----PPLPGV 1182
Query: 247 -LQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHE 305
+ PPP+P PPP P P PP + P + P + P+
Sbjct: 1183 GIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSG 1242
Query: 306 PPSLPPEPKTT 316
PP LP +T
Sbjct: 1243 PPLLPQVGSST 1253
Score = 45.8 bits (107), Expect = 3e-04
Identities = 46/159 (28%), Positives = 59/159 (37%), Gaps = 21/159 (13%)
Query: 192 GVSTVPNTTQASTPPQTQTPQ---PNPPPVQAT----PHPFPAVTPDLIVQTPVMTVVPP 244
G+ P + PP P P PPP+ P P P V P + + PP
Sbjct: 1139 GIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPP 1198
Query: 245 QPLQTPPPVPPQPQP----PPAPAPQPVQSHPPIIAATPQPVKTKKG---VKRKADTTTP 297
PL PP P P PPAPAP P+ PP P P+ G + + +T P
Sbjct: 1199 PPLPGAGIPPPPPLPGMGIPPAPAP-PLP--PPGTGIPPPPLLPVSGPPLLPQVGSSTLP 1255
Query: 298 TTIDPIHEPPSLPPE----PKTTKLGQRRESSRPVKPPK 332
T PP LP G R++ P +P K
Sbjct: 1256 TPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMK 1294
Score = 44.3 bits (103), Expect = 8e-04
Identities = 47/181 (25%), Positives = 64/181 (35%), Gaps = 21/181 (11%)
Query: 185 ETGTAKPGVSTVPNTTQA----STPPQTQTPQPNPPPVQAT------PHPFP--AVTPDL 232
E+ ++ PG+ VP + P T P PPP+Q T P P P + P
Sbjct: 865 ESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPP 924
Query: 233 IVQTPVMTVVPPQP---LQTPPPVPPQPQPPPAPAP-QPVQSHPPIIAATPQPVKTKKGV 288
+ + +PP P + PPP+P PPP P P + PP+ A P G
Sbjct: 925 PLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGA 984
Query: 289 KRKADTTTPTTIDPIHEP---PSLPPEPKTTKLGQRRESSRPVK--PPKKDVPDSQQHPA 343
P P P +PP P G P PP +P + P
Sbjct: 985 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1044
Query: 344 P 344
P
Sbjct: 1045 P 1045
Score = 43.9 bits (102), Expect = 0.001
Identities = 31/67 (46%), Positives = 36/67 (53%), Gaps = 7/67 (10%)
Query: 1264 EDEDALEQARRAHEEARRRQEQQQQQRQ---EQQQQQQQQAAAVAAAATPQAQSSQPQSM 1320
E ED L ++A R Q+QQQQQ Q +QQQQQQQ A AA P A S QP +
Sbjct: 191 EQEDLLSDI----QQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAF 246
Query: 1321 LDQQREL 1327
L R L
Sbjct: 247 LGLDRFL 253
Score = 43.1 bits (100), Expect = 0.002
Identities = 46/169 (27%), Positives = 59/169 (34%), Gaps = 25/169 (14%)
Query: 192 GVSTVPNTTQASTPPQTQTPQ---PNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQP-- 246
G+ P A PP P P PPP+ P P P + P PP P
Sbjct: 1018 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP-----PPLPGA 1072
Query: 247 -LQTPPPVPPQPQPPPAPAP-QPVQSHPPI--IAATPQPVKTKKGVKRKADTTTPTTIDP 302
+ PPP+P PPP P P + PP+ + P P G+ P
Sbjct: 1073 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGI----PPPPPLPGAG 1128
Query: 303 IHEPPSL-----PPEPKTTKLGQRRESSRPVK--PPKKDVPDSQQHPAP 344
I PP L PP P ++G P PP +P + P P
Sbjct: 1129 IPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1177
Score = 43.1 bits (100), Expect = 0.002
Identities = 40/134 (29%), Positives = 47/134 (35%), Gaps = 15/134 (11%)
Query: 192 GVSTVPNTTQASTPPQTQTPQ---PNPPPVQAT----PHPFPAVTPDLIVQTPVMTVVPP 244
G+ P A PP P P PPP+ P P P V P + PP
Sbjct: 1106 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPP 1165
Query: 245 QPL-----QTPPPVPPQPQPPPAPAP-QPVQSHPPIIAA--TPQPVKTKKGVKRKADTTT 296
PL PPP+P PPP P P + PP+ A P P G+
Sbjct: 1166 PPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPL 1225
Query: 297 PTTIDPIHEPPSLP 310
P I PP LP
Sbjct: 1226 PPPGTGIPPPPLLP 1239
Score = 42.0 bits (97), Expect = 0.004
Identities = 44/165 (26%), Positives = 55/165 (33%), Gaps = 17/165 (10%)
Query: 192 GVSTVPNTTQASTPPQTQTPQ---PNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQP-- 246
G+ P A PP P P PPP+ P P P + P PP P
Sbjct: 974 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP-----PPLPGA 1028
Query: 247 -LQTPPPVPPQPQPPPAPAP-QPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIH 304
+ PPP+P PPP P P + PP+ A P G P P
Sbjct: 1029 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1088
Query: 305 EP---PSLPPEPKTTKLGQRRESSRPVK--PPKKDVPDSQQHPAP 344
P +PP P +G P PP +P + P P
Sbjct: 1089 PPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1133
Score = 38.5 bits (88), Expect = 0.044
Identities = 45/169 (26%), Positives = 58/169 (34%), Gaps = 27/169 (15%)
Query: 191 PGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVP-PQPLQT 249
P +P T +S+ P P PPP+ P + V T T +P P PLQ
Sbjct: 856 PSPPPLPCTESSSSMPGLGMVPPPPPPL-----------PGMTVPTLPSTAIPQPPPLQG 904
Query: 250 PPPVPPQPQPP------PAPAPQP---VQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI 300
+PP P PP P P P P + PP+ A P G P
Sbjct: 905 TEMLPPPP-PPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAG 963
Query: 301 DPIHEP---PSLPPEPKTTKLGQRRESSRPVK--PPKKDVPDSQQHPAP 344
P+ P +PP P G P PP +P + P P
Sbjct: 964 IPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1012
Score = 35.8 bits (81), Expect = 0.29
Identities = 48/189 (25%), Positives = 68/189 (35%), Gaps = 10/189 (5%)
Query: 187 GTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQP 246
G P +P PP P PPP+ P P P + + +PP
Sbjct: 1170 GAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPG 1229
Query: 247 LQTPPPVPPQPQPPPAPAPQPVQS---HPPIIAATPQPVKTKK-GVKRKADT-TTPTTID 301
PPP P P P PQ S P + P P+ + G+ D + I+
Sbjct: 1230 TGIPPP-PLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIE 1288
Query: 302 PIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSK--VSEQLKCCSG 359
P P P +L +R+SS + K + P H E SK V E+ K S
Sbjct: 1289 PCR--PMKPLYWTRIQLHSKRDSSTSLIWEKIEEPSIDCHEFEELFSKTAVKERKKPISD 1346
Query: 360 ILKEMFAKK 368
+ + AK+
Sbjct: 1347 TISKTKAKQ 1355
Score = 35.4 bits (80), Expect = 0.38
Identities = 73/329 (22%), Positives = 110/329 (33%), Gaps = 50/329 (15%)
Query: 680 KPQAEKVDVIAGSSKMKGFSS-SESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKH 738
+P AE V+ AG+ + SS S+++ S S+++ ED +++ + +
Sbjct: 157 RPIAEDVETAAGAQDGQRTSSGSDTDIYSFHSATEQEDLLSDIQQAIRLQ---------- 206
Query: 739 HHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPP 798
QQ QQ + QQ QQQQQ P + P +P P
Sbjct: 207 ----QQQQQQLQLQLQQQ--------------QQQQQLQGAEEPAAPPTAVSP----QPG 244
Query: 799 PFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLP-QPPEHSTPPHLNQHAVV 857
F+ +L P G+ P T+ L +LP L +P E PP V
Sbjct: 245 AFLGLDRFLLGPS-GGAGEAPGSPDTEQALSALS-DLPESLAAEPREPQQPPSPGGLPVS 302
Query: 858 SPPALHNALPQQPSRPSNRAAALPP---------KPARPPAVSPALTQTPLLPQPPMAQP 908
P+L A P PS+ A P P R + + P P
Sbjct: 303 EAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSP 362
Query: 909 PQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQ---PPPPLPPPPHPS 965
+ + AP + + Q P LP SQ P PL P +
Sbjct: 363 GEEWAPEVGEDAPQRLGEEPEEEAQGPD--APAAASLPGSPAPSQRCFKPYPLITPCYIK 420
Query: 966 VQQQLQQQPPPPPPPQPQPPPQQQHQPPP 994
+ P P P P+ + +P P
Sbjct: 421 TTTRQLSSPNHSPSQSPNQSPRIKRRPEP 449
Score = 33.5 bits (75), Expect = 1.4
Identities = 33/141 (23%), Positives = 48/141 (34%), Gaps = 9/141 (6%)
Query: 1059 LREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKI--- 1115
L + + + Q Q Q Q QQ +Q ++ + V PQP + ++
Sbjct: 196 LSDIQQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLG 255
Query: 1116 HSPIIRSEPFSPSLRPEPPKH---PESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPP 1172
S P SP PES+ A P+ P+ P G PV P A P
Sbjct: 256 PSGGAGEAPGSPDTEQALSALSDLPESLAAE---PREPQQPPSPGGLPVSEAPSLPAAQP 312
Query: 1173 GAPDKDKQKQEPKTPVAPKKD 1193
A D P P ++
Sbjct: 313 AAKDSPSSTAFPFPEAGPGEE 333
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 123 bits (309), Expect = 1e-27
Identities = 196/884 (22%), Positives = 321/884 (36%), Gaps = 209/884 (23%)
Query: 516 EQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEP-----PP 570
+Q + E+LA++ + ++K K+ +K++KE +EK +R +KS++ P P
Sbjct: 132 KQRQIEQEKLASMKKQDEDKDKR-DKEEKESSREKRERSRS-PRRRKSRSPSPRRRSSPV 189
Query: 571 KKTKKNNSSNS---NVSKKEPAPMKSKPPPTYESEEED-KCKPMSYEEKRQLSLDINKLP 626
++ +K + S S + P+P K T E E K K S +E S DI K+P
Sbjct: 190 RRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTS-DILKVP 248
Query: 627 GEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKV 686
+ I + +EPS + ++ E E ++K +P+
Sbjct: 249 KPE-----PIPEPKEPSPEKNSKKEKE----------------------KEKTRPR---- 277
Query: 687 DVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQM 746
S S S+S S + S + +S+ + + R +
Sbjct: 278 ------------SRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRR----------- 314
Query: 747 QQAPAPVPQQPPPPPQQPPP---PPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIAT 803
P P++ P P ++ PP PPPP+ ++ P A+ + SS +
Sbjct: 315 -----PSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRR--RRRSSASLSGSSSSSSSSRS 367
Query: 804 QVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALH 863
+ P +P P P T+ + P H P PP +TPP P H
Sbjct: 368 RSPPKKP--PKRTSSP-PRKTRRLSPSASPPRRRHRPSPP--ATPP---------PKTRH 413
Query: 864 NALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPL 923
+ PQQ +R ++ P T+ P P L E EE +
Sbjct: 414 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKM 473
Query: 924 TS----MQMQLYLQQLQKVQPPT----------PLLPSVK------------VQSQPPPP 957
+ Q + Y +Q Q+ + P VK +S P P
Sbjct: 474 AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSP 533
Query: 958 LPPPPHPSVQQQLQQQPPPPPP-----PQPQPPPQQQH-----------QPPPRPVHLQP 1001
S + + ++ P PPP P P PPP+++ PPPR P
Sbjct: 534 RKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP 593
Query: 1002 MQFSTHIQQ-----PPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYST 1056
++S IQ+ PPP + P PPP ++ P P P++ + H P+ +S P +
Sbjct: 594 RRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPP--PKRRVSHSPPPKQ-RSSPVTK 650
Query: 1057 GHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQ--PKKQELRAASVVQPQPLVVVKEEK 1114
R +PS H S +S PQ N + P + + P P V+
Sbjct: 651 ---RRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPP---VRRGA 704
Query: 1115 IHSPIIRSEPFSPSLRP----EPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAP 1170
SP R P SPS RP P+ IK P ++ V R V PE A
Sbjct: 705 SSSPQRRQSP-SPSTRPIRRVSRTPEPKKIKKAAS-PSPQSVRRVSSSRSVSGSPEPAAK 762
Query: 1171 PPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRA 1230
P AP Q Q P T +W+ P P AKS + S R +
Sbjct: 763 KPPAPPSPVQSQSPST--------------NWS------PAVPVKKAKSPTPSPSPPRNS 802
Query: 1231 AREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQR 1290
+E ++K K +H + +K + +
Sbjct: 803 DQEGGGKKKKKKKDKKHKKDKKHK-----------------------------------K 827
Query: 1291 QEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQE 1334
++ ++++ AAA AAA TP A ++ ++ ++ A + ++E
Sbjct: 828 HKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKE 871
Score = 103 bits (256), Expect = 1e-21
Identities = 175/803 (21%), Positives = 271/803 (33%), Gaps = 146/803 (18%)
Query: 489 SSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQ-NKPKKKEKDKKEKK 547
+S D D D EE+ + R E +E+ ++ + + P++ + P ++E+ + +
Sbjct: 142 ASMKKQDEDKDKRDKEEKESSR--EKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSR 199
Query: 548 KEKHKRKEEVEE---NKKSKAKEPPPKKTK---------KNNSSNSNVSKKEPAPMKSKP 595
+H+ K KK K E P K + S V K EP P +P
Sbjct: 200 SPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEP 259
Query: 596 PPTYESEEE---DKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPS-LKNSNPDE 651
P S++E +K +P S + S ++ P R H +SR S + +P
Sbjct: 260 SPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRR 319
Query: 652 IEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSS 711
P + R+ R+ R P + S+ + G SSS S S S S
Sbjct: 320 RPSPRRRTPPRRMPPPPRH-----RRSRSPVRRRR---RSSASLSGSSSSSSSSRSRSPP 371
Query: 712 SDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQ 771
T P+ ++ P + H P+P P PPP + P P
Sbjct: 372 K-KPPKRTSSPPRKTRRLSPSASPPRRRHR--------PSP-PATPPPKTRHSPTPQQSN 421
Query: 772 QQQQP----PPPPPPPSMPQQAAPAMKSSPPPFIATQVPVL---EPQLPGSVF--DPIGH 822
+ ++ P + + + SP P + L E G + D +
Sbjct: 422 RTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQ 481
Query: 823 FTQPILHLPQPELPPHLPQPPEHSTPPHLN-QHAVVSPPALHNALPQQPSRPSNRAAALP 881
Q Q E P + ++ V H+ P R
Sbjct: 482 RRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETS 541
Query: 882 PKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPP 941
P+ R + SP T+ P P A PP+ P PP ++ PP
Sbjct: 542 PRGRRRRSPSPPPTRRRRSPSP--APPPR---RRRTPTPPP----------RRRTPSPPP 586
Query: 942 TPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPP---PQPQPPPQQQ--HQPPPRP 996
PS + S PP+ PS + + PPPPP P PPP+++ H PPP+
Sbjct: 587 RRRSPSPRRYS---PPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPK- 642
Query: 997 VHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHK-SDPYS 1055
Q+ P ++ P S +H K S P
Sbjct: 643 ------------QRSSPVTKRRSP----------------------SLSSKHRKGSSPSR 668
Query: 1056 TGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKI 1115
+ +P P HSP T SPP V+
Sbjct: 669 STREARSPQPNKRHSPSPRPRAPQTSSSPPP-----------------------VRRGAS 705
Query: 1116 HSPIIRSEPFSPSLRP----EPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPP 1171
SP R P SPS RP P+ IK P ++ V R V PE A
Sbjct: 706 SSPQRRQSP-SPSTRPIRRVSRTPEPKKIKKAAS-PSPQSVRRVSSSRSVSGSPEPAAKK 763
Query: 1172 PGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAA 1231
P AP Q Q P T +P +K + TPS + +SD ++
Sbjct: 764 PPAPPSPVQSQSPSTNWSPAVPVK-----------KAKSPTPSPSPPRNSDQEGGGKKKK 812
Query: 1232 REKEEREKALKAQAEHAEKEKER 1254
++K+++ K K +H + +KE+
Sbjct: 813 KKKDKKHKKDKKHKKHKKHKKEK 835
Score = 83.2 bits (204), Expect = 2e-15
Identities = 122/608 (20%), Positives = 219/608 (36%), Gaps = 116/608 (19%)
Query: 456 KMPDEPEEPVVAVSSPAVPPPTKV-----VAPPSSSDSSSDSSSDSDSSTDDSEEERAQR 510
K P+ PE P V V P+V T V P + S + +S + +E+ R
Sbjct: 219 KTPELPE-PSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPR 277
Query: 511 LAELQEQLKAVHEQLAALSQPQQN--------------------KPKKKEKDKKEKKKEK 550
+ + + ++P++ P+++ ++ +
Sbjct: 278 SRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPR 337
Query: 551 HKR-KEEVEENKKSKAK-------------EPPPKKTKKNNSSNSNVSKK-----EPAPM 591
H+R + V ++S A PPKK K SS +++ P
Sbjct: 338 HRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRR 397
Query: 592 KSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDE 651
+ +P P + + P + R ++ PG G+V + + + P
Sbjct: 398 RHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKP 457
Query: 652 IEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESE------- 704
+++ + ++ + R++ + Q ++ +GSS SSSE E
Sbjct: 458 RKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSS-----SSSEDERPKRSHV 512
Query: 705 -----------SSSESSSSDSEDSETEMAPKSKKKGHPG----REQKKHHHHHHQQMQQA 749
S S S+S + E +P+ +++ P R ++ + ++
Sbjct: 513 KNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRT 572
Query: 750 PAPVPQQ--PPPPPQQ----------------PPPPPPPQQQQQPPPPPPPPSMPQQAAP 791
P P P++ P PPP++ P PPP ++ PPPPP + P
Sbjct: 573 PTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPK 632
Query: 792 AMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPI-----LHLPQP---ELPPHLPQPP 843
S PP PV + + P S+ + P PQP P P+ P
Sbjct: 633 RRVSHSPPPKQRSSPVTKRRSP-SLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAP 691
Query: 844 E-HSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALP-PKPARPPAVSPALTQTPLLP 901
+ S+PP + + A SP + P +RP R + P PK + A + +
Sbjct: 692 QTSSSPPPVRRGASSSPQRRQS--PSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSS 749
Query: 902 QPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKV-QSQPPPPLPP 960
++ P+ ++PPAPP +Q P T P+V V +++ P P P
Sbjct: 750 SRSVSGSPEPAA--KKPPAPP----------SPVQSQSPSTNWSPAVPVKKAKSPTPSPS 797
Query: 961 PPHPSVQQ 968
PP S Q+
Sbjct: 798 PPRNSDQE 805
Score = 82.0 bits (201), Expect = 4e-15
Identities = 131/636 (20%), Positives = 212/636 (33%), Gaps = 140/636 (22%)
Query: 474 PPPTKVVAPPSSSDSSSDSSSD---SDSSTDDSEEERAQRLAELQEQLKAVHE------- 523
P P + +P S S S + S + E+ ++ EL E V E
Sbjct: 180 PSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEAT 239
Query: 524 ---QLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSK------AKEPPPKKTK 574
+ + +P+ K+ +K KKEK K K +SK ++ P + +
Sbjct: 240 STSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPR 299
Query: 575 KNNSSNSN--------VSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDIN--- 623
+ + S S ++ P+P + PP + +R+ S ++
Sbjct: 300 RRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSS 359
Query: 624 ------------KLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYV 671
K P ++ + PS T P T
Sbjct: 360 SSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQ 419
Query: 672 TSCLRKKR--------------------------KPQAEKVDVIAGSSKMKGFSSSESES 705
++ RK R P+ KV+ ++ S + KG + ++S
Sbjct: 420 SNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVE-LSESEEDKGGKMAAADS 478
Query: 706 ------------SSESSSSDSEDSETEMAPKSK-KKGHPGREQKKHHHHHHQQMQQAPAP 752
S S S S SE E +S K G GR ++ H +P+P
Sbjct: 479 VQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRR-----HSPSRSASPSP 533
Query: 753 VPQQ------------PPPPP----QQPPPPPPPQQQQQPPPPP---PPPSMPQQAAPAM 793
+Q P PPP + P P PPP++++ P PPP P P++ +P+
Sbjct: 534 RKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP 593
Query: 794 KSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPP-----HLPQPPEHSTP 848
+ PP P P+ + P P P PP H P P + S+P
Sbjct: 594 RRYSPPIQRRYSPSPPPKRRTASPPP------PPKRRASPSPPPKRRVSHSPPPKQRSSP 647
Query: 849 PHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQP 908
+ +S + PSR + A + P P+ P QT P PP+ +
Sbjct: 648 VTKRRSPSLSS---KHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSP-PPVRRG 703
Query: 909 PQVLLEDEEPPAP---PLTSMQMQLYLQQLQKVQPPTP-----LLPSVKVQSQP-----P 955
+ + P+P P+ + ++++K P+P + S V P
Sbjct: 704 ASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKK 763
Query: 956 PPLPPPPHPSVQQQLQQQPPPP------PPPQPQPP 985
PP PP P S P P P P P PP
Sbjct: 764 PPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPP 799
Score = 77.8 bits (190), Expect = 7e-14
Identities = 139/695 (20%), Positives = 233/695 (33%), Gaps = 112/695 (16%)
Query: 661 PSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETE 720
PS EL++ K+R+ + EK+ + MK + + E S E E
Sbjct: 120 PSAFLELKKEEI----KQRQIEQEKL------ASMKKQDEDKDKRDKEEKESSREKRERS 169
Query: 721 MAPKSKKKGHPG---------REQKKHHHH--HHQQMQQAPAPVPQQPPPPPQQPPPPPP 769
+P+ +K P RE+K+ H H+ ++P+P P++ P+ P P
Sbjct: 170 RSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEP--- 226
Query: 770 PQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILH 829
V V EP + + T IL
Sbjct: 227 ----------------------------------SVKVKEPSVQEATS------TSDILK 246
Query: 830 LPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKP--ARP 887
+P+PE P +P + P + + + +R + + P + +R
Sbjct: 247 VPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRS 306
Query: 888 PAVSPALTQTPLL-PQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLP 946
+ SP +P P P PP+ + PP P + + ++
Sbjct: 307 RSYSPRRRPSPRRRPSPRRRTPPRRM-----PPPPRHRRSRSPVRRRRRSSASLSGSSSS 361
Query: 947 SVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFST 1006
S +S+ PP PP S ++ ++ P PP+ + P PPP+ H Q S
Sbjct: 362 SSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSN 421
Query: 1007 HIQQ------PPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLR 1060
++ P G+ H ++ P KP++V +S+ G +
Sbjct: 422 RTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKV-------ELSESEEDKGGKMA 474
Query: 1061 EAPS--PLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASV-----------VQPQPL 1107
A S + Q Q S + S ++ +PK+ ++ V P P
Sbjct: 475 AADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPR 534
Query: 1108 VVVKEEKIHSPIIRSEPFSPSLR---PEPPKHPESIKAPVHLPQRPEMKPVDVGR-PVIR 1163
KE RS P+ R P P P + P P+R P R P R
Sbjct: 535 KRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPR 594
Query: 1164 ---PPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSS 1220
PP Q P P K + P P S K ++P + +S
Sbjct: 595 RYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSP 654
Query: 1221 SDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARR-AHEEA 1279
S S + + ++ + RE A + K R R+ + + RR A
Sbjct: 655 SLSSKHRKGSSPSRSTRE------ARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSP 708
Query: 1280 RRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQS 1314
+RRQ R ++ + + + AA+P QS
Sbjct: 709 QRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQS 743
Score = 65.9 bits (159), Expect = 3e-10
Identities = 103/445 (23%), Positives = 159/445 (35%), Gaps = 109/445 (24%)
Query: 182 GRKETGTAKPGVSTVPNTTQASTPPQTQTPQ-PNPPPVQATPHPFPAVTPDLIVQTPVMT 240
GR+ + S P Q T P+ + + P+PPP + P PA
Sbjct: 518 GRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPA------------- 564
Query: 241 VVPPQPLQTPPPVPPQPQPPPAP---APQPVQSHPPIIAATPQPVKTKKGVKRKADTTTP 297
PP+ +TP P P + P P P +P P + PPI +R+ + P
Sbjct: 565 -PPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPI--------------QRRYSPSPP 609
Query: 298 TTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLKCC 357
P S PP PK RR S P PPK+ V S P ++SS V+++
Sbjct: 610 ----PKRRTASPPPPPK------RRASPSP--PPKRRV--SHSPPPKQRSSPVTKRR--- 652
Query: 358 SGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQE 417
S L KH S +S EAR + +
Sbjct: 653 SPSLSS-------------------------------KHRKGSSPSRSTREARSPQPNKR 681
Query: 418 FGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPT 477
R PP + + + + + P P+ VS P
Sbjct: 682 HSPSPRPRAPQTSSSPPPVRRGASSSPQRR--------QSPSPSTRPIRRVSRTPEPKKI 733
Query: 478 KVVAPPSSSDSSSDSSSDSDS-STDDSEEERAQRLAELQEQ-----------LKAVHEQL 525
K A PS SSS S S S + + ++ + +Q Q +K
Sbjct: 734 KKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPT 793
Query: 526 AALSQPQQN------KPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSS 579
+ S P+ + K KKK+KDKK KK +KHK+ ++ ++ K A ++
Sbjct: 794 PSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAA 853
Query: 580 NSNVSKKEPAPMKSKPPPTYESEEE 604
+ ++++EP + P P E+E E
Sbjct: 854 TTTLAQEEPV---AAPEPKKETESE 875
Score = 53.9 bits (128), Expect = 1e-06
Identities = 47/183 (25%), Positives = 69/183 (37%), Gaps = 28/183 (15%)
Query: 181 RGRKETGTAKPGVSTVPNTTQASTPPQTQTPQP-------NPPPVQATPHPFPAVTPDLI 233
RGR+ + P + + A P + +TP P +PPP + +P P P
Sbjct: 543 RGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPP--- 599
Query: 234 VQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPV----------K 283
+Q PP+ PP PP+ + P+P P+ SH P PV K
Sbjct: 600 IQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSK 659
Query: 284 TKKGVKRKADTTTPTTIDP--IHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQH 341
+KG T + P H P P P+T+ S PV+ P +Q
Sbjct: 660 HRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTS------SSPPPVRRGASSSPQRRQS 713
Query: 342 PAP 344
P+P
Sbjct: 714 PSP 716
Score = 42.7 bits (99), Expect = 0.002
Identities = 57/265 (21%), Positives = 106/265 (40%), Gaps = 36/265 (13%)
Query: 1085 PQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPV 1144
P ++ KK+E++ + Q + + K+++ + E S + E + P K+
Sbjct: 120 PSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRS 179
Query: 1145 HLPQRPEMKPV--DVGRPVIRPPE---QNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNM 1199
P+R PV + R R P ++ P AP+K + KTP P+ +K+K
Sbjct: 180 PSPRR-RSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKE-----KTPELPEPSVKVKEP 233
Query: 1200 GSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQER 1259
VQ+ +T + + + + EK ++ EKEKE+ R R
Sbjct: 234 S-----VQEATSTSDILKVPKPEPIPEPKEPSPEKNSKK----------EKEKEKTR-PR 277
Query: 1260 MRSREDEDALEQARR-AHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQ 1318
RSR + ++R +H RRR + + +++ ++ + P+ P+
Sbjct: 278 SRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPR 337
Query: 1319 SMLDQQRELARKREQERRRREAMAA 1343
R R RRRR + A+
Sbjct: 338 H--------RRSRSPVRRRRRSSAS 354
Score = 39.7 bits (91), Expect = 0.020
Identities = 102/589 (17%), Positives = 183/589 (31%), Gaps = 70/589 (11%)
Query: 244 PQPLQTPPP---VPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI 300
P P + P P PP+ PPP P+ +S P+ + ++ + +++ ++
Sbjct: 315 PSPRRRPSPRRRTPPRRMPPP---PRHRRSRSPVR-------RRRRSSASLSGSSSSSSS 364
Query: 301 DPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKK---------DVPDSQQHPAPEKS---- 347
PP PP+ ++ + R S PP++ P ++ P P++S
Sbjct: 365 SRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTR 424
Query: 348 -SKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSK 406
S+VS SG + + + P KP VE + M+ S
Sbjct: 425 KSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEE-----DKGGKMAAADSV 479
Query: 407 LEAREYRDAQEFGADVRLMFSNCYKYNP-----------------PDHEVVAMARKLQDV 449
+ R+YR + + S+ P P RK Q
Sbjct: 480 QQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKE 539
Query: 450 FEMRFAKMPDEPEEPVVAVSSPAVPPPTK----VVAPPSSSDSSSDSSSDSDSSTDDSEE 505
R + P SP+ PP + PP S S S S
Sbjct: 540 TSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYS-- 597
Query: 506 ERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKA 565
+Q + + P ++ K++ H + + +K
Sbjct: 598 ------PPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKR 651
Query: 566 KEP--PPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDIN 623
+ P K K ++ S S + P P K P + P S
Sbjct: 652 RSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRR 711
Query: 624 KLPGEKLGRVVHIIQSREPS--LKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKP 681
+ P + + ++ EP K ++P + + S+ R + +K P
Sbjct: 712 QSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSV----RRVSSSRSVSGSPEPAAKKPPAP 767
Query: 682 QAEKVDVIAGSSKMKGFSSSESESSSESSSSD-SEDSETEMAPKSKKKGHPGREQKKHHH 740
+ ++ +++S + S S + D E K KKK ++ KKH
Sbjct: 768 PSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKK 827
Query: 741 HHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQA 789
H + ++A A P Q++ P P +A
Sbjct: 828 HKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKETESEA 876
Score = 34.3 bits (77), Expect = 0.84
Identities = 29/143 (20%), Positives = 54/143 (37%), Gaps = 15/143 (10%)
Query: 181 RGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMT 240
R R + +++ ++ +S+ ++++P PP ++P P T L
Sbjct: 340 RSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSP---PRKTRRL-------- 388
Query: 241 VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI 300
P +PP +P PP P P+ S P + + + R + T
Sbjct: 389 ----SPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKG 444
Query: 301 DPIHEPPSLPPEPKTTKLGQRRE 323
E PS P+P+ +L + E
Sbjct: 445 TEKRESPSPAPKPRKVELSESEE 467
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 123 bits (308), Expect = 1e-27
Identities = 115/353 (32%), Positives = 136/353 (38%), Gaps = 45/353 (12%)
Query: 743 HQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPP--PSMPQQAAPAMKSSPPPF 800
H + PAP P Q PP P PPP P PPP PP S P Q P+ SP
Sbjct: 557 HLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSP--- 613
Query: 801 IATQVPVLEP--QLPGSVFDPIGHFTQPI--LHLPQPELP----PHLPQPPEHSTPPHLN 852
+AT P P LP P + P+ L P P+ P HL Q P S PP
Sbjct: 614 LATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP-FSPPPSPP 672
Query: 853 QHAVVSPPA----LHNALPQQPSRPSNRAAAL--PPKPARPPAVSPALTQTPLLPQPPMA 906
A SPPA +A P + PS A L PP P P +SP+ T P P PP+A
Sbjct: 673 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP-PPLA 731
Query: 907 QPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSV 966
PP + PP+PP + + P P +P + + PP +PP P S+
Sbjct: 732 APPL-----QVPPSPPAS--------PPMSPSATPPPRVP--PLLAAPPLQVPPSPPASL 776
Query: 967 QQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPG- 1025
+PPP PP PP Q PP Q FS P P PP PP
Sbjct: 777 PMSPLAKPPPQAPPALATPPLQALPSPPASFPGQ-APFSPSASLPMSPLATPPPQAPPVL 835
Query: 1026 ----QQPPPPQPAKPQQVIQHH---HSPRHHKSDPYSTGHLREAPSPLMIHSP 1071
Q PP PA P P S P T L P P SP
Sbjct: 836 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 888
Score = 120 bits (300), Expect = 1e-26
Identities = 138/465 (29%), Positives = 164/465 (35%), Gaps = 74/465 (15%)
Query: 750 PAPVPQQPP---PPPQQPPPPP-PPQQQQQPPPPPPPPSMPQQAAPAMKSSP---PPFIA 802
PA +P PP P P PP P PP Q P PP PPS QA P+M + P PP +
Sbjct: 328 PATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPS---QAPPSMTTPPMQAPPSLQ 384
Query: 803 TQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPAL 862
T P+ Q+P S+ T P L P L Q P L A
Sbjct: 385 TIPPI---QVPHSL-------TSPSLQAPPSPLALSSLQATTSLGSPTLQ--------AT 426
Query: 863 HNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPP 922
H+ L P R + + P +PA P SP L LP P Q L P + P
Sbjct: 427 HSFLTMSP-RQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTS--LSPAVSPLSSP 483
Query: 923 LTSMQMQLYLQQLQKVQPPTPL----LPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPP 978
LT +Q L L P PL +P ++ QS PP P S+ PP
Sbjct: 484 LTIHPLQA-LSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASL-----TTPPLEN 537
Query: 979 PPQPQPPPQQQHQPPPRPVHLQ--PMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQ--PA 1034
P PPP Q P HL+ P +Q PP P PP P PPPQ PA
Sbjct: 538 LPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPA 597
Query: 1035 KPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTH-QSPPQQNVQPKK 1093
+Q SP SPL PQ +L Q+PP P
Sbjct: 598 LASPPLQGLPSP---------------PLSPLATPPPQAPPXLALPPLQAPPSPPASPPL 642
Query: 1094 QELRAASVVQPQPLVVVKEEKIHSP-----------IIRSEPFSPSLRPEPPKHPESIKA 1142
L S P L V + SP S P SPS P P
Sbjct: 643 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 702
Query: 1143 PVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTP 1187
P+ +P P P P PP Q PP AP P +P
Sbjct: 703 PLQVPPSPPASP--PMSPSATPPPQAPPPLAAPPLQVPPSPPASP 745
Score = 120 bits (300), Expect = 1e-26
Identities = 134/501 (26%), Positives = 163/501 (32%), Gaps = 91/501 (18%)
Query: 758 PPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVF 817
P P PP PP Q P PP + +PA+ P + L S
Sbjct: 444 PSRPASTPPDSPPLQAPLSLPASPP--LQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQ 501
Query: 818 DPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALP-------QQP 870
P+ P L PP L PP T P L ++PP L A + P
Sbjct: 502 APLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETP 561
Query: 871 SRPSNRAAALPPKP-------------ARPPAVSPALTQTPL--LPQPPMA----QPPQ- 910
P+ PP P PP PAL PL LP PP++ PPQ
Sbjct: 562 PCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQA 621
Query: 911 ----VLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSV 966
L + PP+PP + L + P+P P+ P PPP P V
Sbjct: 622 PPXLALPPLQAPPSPPAS--------PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV 673
Query: 967 QQQLQQQPPPPPPPQPQPPPQQQH-------QPPPRPVHLQPMQFSTHIQQPPPPQGQQP 1019
Q PP P PP Q Q PP P PM S PPPQ P
Sbjct: 674 QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA----TPPPQAPPP 729
Query: 1020 PHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSL 1079
PP Q PP P PA P SP + P L AP + SP S S
Sbjct: 730 LAAPPLQVPPSP-PASPPM------SP--SATPPPRVPPLLAAPPLQVPPSPPASLPMSP 780
Query: 1080 THQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPES 1139
+ PPQ A + PL + P PFSPS
Sbjct: 781 LAKPPPQ-----------APPALATPPLQALPSPPASFP--GQAPFSPS----------- 816
Query: 1140 IKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNM 1199
LP P P PV+ P PP +P Q P+ P P D +
Sbjct: 817 ----ASLPMSPLATPPPQAPPVLAAPLLQVPP--SPPASPTLQAPRRPPTPGPDTSVSGP 870
Query: 1200 GSWASLVQKHPTTPSSTAKSS 1220
+L P PS + S+
Sbjct: 871 RLTLALAPGPPPPPSRSPSST 891
Score = 92.0 bits (227), Expect = 3e-18
Identities = 95/322 (29%), Positives = 116/322 (36%), Gaps = 49/322 (15%)
Query: 748 QAPAPVPQQPP------PPPQQP-------------PPPPPPQQQQQPPPPPPPPSM--- 785
QAP P PP P PQ P PPP PP Q PP PP S
Sbjct: 631 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 690
Query: 786 -PQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPE 844
P QA P++ + P QVP P P P+ P P P P L PP
Sbjct: 691 PPSQAPPSLAAPP-----LQVPPSPPASP-----PMSPSATPPPQAPPPLAAPPLQVPPS 740
Query: 845 HSTPPHLNQHAVVSP--PALHNALPQQPSRPSNRAAALPPKPAR--PPAVSPALTQTPL- 899
P ++ A P P L A P Q P + A+LP P PP PAL PL
Sbjct: 741 PPASPPMSPSATPPPRVPPLLAAPPLQV--PPSPPASLPMSPLAKPPPQAPPALATPPLQ 798
Query: 900 -LPQPPMAQPPQVLLEDEEP-PAPPLTSMQMQ---LYLQQLQKVQPPTPLLPSVKVQSQP 954
LP PP + P Q P PL + Q + L +V P P P+++ +P
Sbjct: 799 ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP 858
Query: 955 PPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQ--PP 1012
P P P + L P PPPP P P P H + +
Sbjct: 859 PTPGPDTSVSGPRLTLALAPGPPPP--PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 916
Query: 1013 PPQGQQPPHPPPGQQPPPPQPA 1034
P+G PPP + PA
Sbjct: 917 GPEGGAAASPPPDAELAACHPA 938
Score = 90.5 bits (223), Expect = 1e-17
Identities = 134/523 (25%), Positives = 177/523 (33%), Gaps = 92/523 (17%)
Query: 750 PAPVPQQPPPPPQQPP------------PPPPPQQQQQP--------------------- 776
P P P P PP + P P P +++P
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249
Query: 777 --PPPPPPPSMPQQAAPAMKSSPPP--FIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQ 832
P P + APA S P P A + P + P + +G + L P
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA-PALGPLSSSPLATPS 308
Query: 833 PELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAA--ALPPKPARPPAV 890
P P PP + L SPP L LP P PS + LP PA PP+
Sbjct: 309 PSGTKARPVPPPDNAATPLPATLPPSPP-LATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 367
Query: 891 SPALTQTPLLPQPPMAQ--PPQVLLED------EEPPAP-PLTSMQMQL-----YLQQLQ 936
+P TP + PP Q PP + + PP+P L+S+Q LQ
Sbjct: 368 APPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATH 427
Query: 937 KVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRP 996
+P + S P PP P +Q L P PP Q P P P
Sbjct: 428 SFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSL--PASPPLQTSLSPAV--SPLSSP 483
Query: 997 VHLQPMQ----FSTHIQQPP------PPQGQQPPHPPPGQQPPPPQPAKP--QQVIQHHH 1044
+ + P+Q ++H Q P PP Q PP Q PP P + +
Sbjct: 484 LTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAP 543
Query: 1045 SPRHHKSDPYSTGH-----------LREAPSPLMIHSPQM-SQFQSLTHQSPPQQNVQP- 1091
P S P +T H L+ PSPL P+ S + Q+PP P
Sbjct: 544 PPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPL 603
Query: 1092 ---KKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKA-PVHLP 1147
L + PQ + + +P S P SP L P P++ A VHL
Sbjct: 604 QGLPSPPLSPLATPPPQAPPXLALPPLQAP--PSPPASPPLSPLATPSPQAPNALAVHLL 661
Query: 1148 QRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAP 1190
Q P P PV P A PP +P Q P + AP
Sbjct: 662 QAPFSPP--PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 702
Score = 68.9 bits (167), Expect = 3e-11
Identities = 137/588 (23%), Positives = 185/588 (31%), Gaps = 102/588 (17%)
Query: 623 NKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQ 682
NK K G +R P L P + P+ LR L + RKP
Sbjct: 3 NKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLG----AAGAVGRKPL 58
Query: 683 AEKVDVIAG-----SSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKK 737
AE+ I G S+ G + S SS +S E AP +K PG
Sbjct: 59 AERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTS-PG----- 112
Query: 738 HHHHHHQQMQQAPAPVPQQP-----PPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPA 792
P P + P P Q ++ P +A A
Sbjct: 113 ------------PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGA 160
Query: 793 MKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLN 852
+ + P T P + + + T+ L P P P P + +
Sbjct: 161 RRDTSGPTPGTPSPAMARRSRAAG-------TEVGLPRPAPSARPRPPTEGPRKSVSSAS 213
Query: 853 QHAVVSPPALHNALPQQPS---RPSNRAAALPPKPARPPAVS-PALTQTPLLPQPPMAQP 908
+H+ P P RP++R+ + P PA S P+ TP P P +QP
Sbjct: 214 EHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP-SQP 272
Query: 909 PQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPP-----PLPP--P 961
L+ PP L L TP K + PPP PLP P
Sbjct: 273 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLP 332
Query: 962 PHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPH 1021
P P + P P PP P PP Q P P +T Q PP P
Sbjct: 333 PSPPLAT-----PLPLAPPSPSAPPSLQTLPSPP---------ATPPSQAPPSMTTPPMQ 378
Query: 1022 PPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIH---------SPQ 1072
PP Q PP IQ HS ++ L+ PSPL + SP
Sbjct: 379 APPSLQTIPP--------IQVPHS--------LTSPSLQAPPSPLALSSLQATTSLGSPT 422
Query: 1073 MSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRS-----EPFSP 1127
+ S SP Q A++ PL P+ S P S
Sbjct: 423 LQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSS 482
Query: 1128 SLRPEPPKHPESIKAPVHLPQRP----EMKPVDVGRPVIRPPEQNAPP 1171
L P + S+ + H PQ P M P++ + + PP PP
Sbjct: 483 PLTIHPLQALSSLAS--HSPQAPLSSLIMPPLET-QSSLAPPSLQTPP 527
Score = 60.1 bits (144), Expect = 1e-08
Identities = 47/146 (32%), Positives = 57/146 (39%), Gaps = 27/146 (18%)
Query: 185 ETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQ---TPVMTV 241
++ A P + T P +TPP P PPP+Q P TP L P
Sbjct: 515 QSSLAPPSLQTPP--ASLTTPPLENLPSLAPPPLQTASAPL--TTPHLETPPCPAPCPLQ 570
Query: 242 VPPQPLQTPPP------VPPQPQPPPAPAPQPVQS--HPPII-AATPQPVKTKKGVKRKA 292
PP PL TPPP P PQ PPA A P+Q PP+ ATP P
Sbjct: 571 APPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPP----------- 619
Query: 293 DTTTPTTIDPIHEPPSLPPEPKTTKL 318
+ P+ PPS P P + L
Sbjct: 620 QAPPXLALPPLQAPPSPPASPPLSPL 645
Score = 57.8 bits (138), Expect = 7e-08
Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 18/176 (10%)
Query: 197 PNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPV----------MTVVPPQP 246
P + +TPP P PP+QA P P PA P + TP + P P
Sbjct: 609 PPLSPLATPPPQAPPXLALPPLQAPPSP-PASPPLSPLATPSPQAPNALAVHLLQAPFSP 667
Query: 247 LQTPP---PVPPQPQPPPAPAPQPVQSHPPIIAATP---QPVKTKKGVKRKADTTTPTTI 300
+PP P P PP +P+ P PP +AA P P + T P
Sbjct: 668 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 727
Query: 301 DPIHEPP-SLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLK 355
P+ PP +PP P + + P PP P Q P+P S +S K
Sbjct: 728 PPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAK 783
Score = 54.7 bits (130), Expect = 6e-07
Identities = 49/158 (31%), Positives = 60/158 (37%), Gaps = 23/158 (14%)
Query: 191 PGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVP---PQPL 247
P P + ++TPP P PP+Q P P PA P TP V P PL
Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP-PASPPMSPSATPPPRVPPLLAAPPL 766
Query: 248 QTPPPVP----------PQPQPPPAPAPQPVQSHPPIIAATP--QPVKTKKGVKRKADTT 295
Q PP P P PQ PPA A P+Q+ P A+ P P + T
Sbjct: 767 QVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 826
Query: 296 TPTTIDPIHEPPSL--PPEPKTTKLGQRRESSRPVKPP 331
P P+ P L PP P + Q P +PP
Sbjct: 827 PPPQAPPVLAAPLLQVPPSPPASPTLQ-----APRRPP 859
Score = 53.5 bits (127), Expect = 1e-06
Identities = 43/142 (30%), Positives = 53/142 (37%), Gaps = 10/142 (7%)
Query: 213 PNPPPVQATPHPF-PAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQP--QPPPAPAPQPVQ 269
P PPVQA PF P +P + + PP P VPP P PP +P+ P
Sbjct: 668 PPSPPVQA---PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 724
Query: 270 SHPPIIAATP--QPVKTKKGVKRKADTTTPTTIDPIHEPPSL--PPEPKTTKLGQRRESS 325
PP +AA P P T P + P+ P L PP P +
Sbjct: 725 QAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP 784
Query: 326 RPVKPPKKDVPDSQQHPAPEKS 347
P PP P Q P+P S
Sbjct: 785 PPQAPPALATPPLQALPSPPAS 806
Score = 52.8 bits (125), Expect = 2e-06
Identities = 52/164 (31%), Positives = 62/164 (37%), Gaps = 21/164 (12%)
Query: 197 PNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPP--QPLQTPPP-V 253
P QA P T TP P P ATP P P + P+ + P PL TPPP
Sbjct: 566 PCPLQAPPSPLT-TPPPETPSSIATP---PPQAPPALASPPLQGLPSPPLSPLATPPPQA 621
Query: 254 PPQPQPPPAPAPQPVQSHPPII-AATPQP-VKTKKGVKRKADTTTPTTIDPIH---EPPS 308
PP PP AP + PP+ ATP P V +P P+ PP+
Sbjct: 622 PPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 681
Query: 309 LPP-EPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVS 351
PP P T Q PP P Q P+P S +S
Sbjct: 682 SPPVSPSATPPSQ--------APPSLAAPPLQVPPSPPASPPMS 717
Score = 47.0 bits (110), Expect = 1e-04
Identities = 53/203 (26%), Positives = 74/203 (36%), Gaps = 62/203 (30%)
Query: 189 AKPGVSTVP--NTTQASTPPQTQTPQPNP--------------PPVQATPHPFPAVTPDL 232
A P + T+P + T P Q P P+P P +QAT H F ++P
Sbjct: 379 APPSLQTIPPIQVPHSLTSPSLQAP-PSPLALSSLQATTSLGSPTLQAT-HSFLTMSPR- 435
Query: 233 IVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQS---------------HP----- 272
QT P +P TPP PP P PA P+Q+ HP
Sbjct: 436 --QTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALS 493
Query: 273 ---------PIIAATPQPVKTKKGVKRKADTTTPT--TIDPIHEPPSLPPEPKTTKLGQR 321
P+ + P++T+ + + T P T P+ PSL P P T
Sbjct: 494 SLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQT----- 548
Query: 322 RESSRPVKPPKKDVPDSQQHPAP 344
+S P+ P + P PAP
Sbjct: 549 --ASAPLTTPHLETPPC---PAP 566
Score = 46.6 bits (109), Expect = 2e-04
Identities = 49/176 (27%), Positives = 67/176 (38%), Gaps = 19/176 (10%)
Query: 180 GRGRKETGTAKPGVSTVPNTTQASTPPQTQ-TPQPNPPPVQATPHPF-----PAVTPDLI 233
G G + + S P ++ A + P + TP+ P Q P P VTP
Sbjct: 231 GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 290
Query: 234 VQTPVMTVVPPQPLQTPPP--VPPQPQPPP----APAPQPVQSHPPIIAATPQPVKTKKG 287
P + + PL TP P +P PPP P P + PP+ ATP P+
Sbjct: 291 DAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPL--ATPLPLAPP-- 346
Query: 288 VKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPA 343
A + T P PPS P TT Q S + + P + VP S P+
Sbjct: 347 -SPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQ--VPHSLTSPS 399
Score = 46.6 bits (109), Expect = 2e-04
Identities = 48/151 (31%), Positives = 53/151 (35%), Gaps = 33/151 (21%)
Query: 197 PNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTP-----P 251
P QA PPQ P+ + P P TP T V PP TP P
Sbjct: 274 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS-GTKARPVPPPDNAATPLPATLP 332
Query: 252 PVPP--QPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTP-------TTIDP 302
P PP P P P+P S PP + P P T + TT P TI P
Sbjct: 333 PSPPLATPLPLAPPSP----SAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPP 388
Query: 303 IHEPPSL-------PPEP-------KTTKLG 319
I P SL PP P TT LG
Sbjct: 389 IQVPHSLTSPSLQAPPSPLALSSLQATTSLG 419
Score = 37.4 bits (85), Expect = 0.099
Identities = 42/158 (26%), Positives = 56/158 (35%), Gaps = 32/158 (20%)
Query: 191 PGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTP-----------DLIVQTPVM 239
P P + ++TPP P PP+Q P P PA P + TP +
Sbjct: 739 PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSP-PASLPMSPLAKPPPQAPPALATPPL 797
Query: 240 TVVPPQPLQTPPPVPPQPQ------PPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKAD 293
+P P P P P P P PQ PP++AA V +
Sbjct: 798 QALPSPPASFPGQAPFSPSASLPMSPLATPPPQA----PPVLAAPLLQVP-------PSP 846
Query: 294 TTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPP 331
+PT P PP+ P P T+ G R + PP
Sbjct: 847 PASPTLQAP-RRPPT--PGPDTSVSGPRLTLALAPGPP 881
Score = 37.4 bits (85), Expect = 0.099
Identities = 37/123 (30%), Positives = 46/123 (37%), Gaps = 11/123 (8%)
Query: 196 VPNTTQASTPPQTQT-PQPNPPPVQATP--HPFPAVTPDLIVQTPV--MTVVPPQPLQTP 250
VP + AS P P P PP ATP P+ Q P +P PL TP
Sbjct: 768 VPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 827
Query: 251 PPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLP 310
P PQ PP A P+ PP A+P ++ DT+ + P P
Sbjct: 828 P-----PQAPPVLA-APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 881
Query: 311 PEP 313
P P
Sbjct: 882 PPP 884
Score = 35.8 bits (81), Expect = 0.29
Identities = 28/101 (27%), Positives = 39/101 (38%), Gaps = 8/101 (7%)
Query: 197 PNTTQASTPPQT-QTPQPNPPPVQATP----HPFPAVTPDLIVQTPVMTVVPPQPLQTPP 251
P + AS P TP P PPV A P P P +P L T P + P
Sbjct: 812 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR 871
Query: 252 ---PVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVK 289
+ P P PPP+ +P S P + + T + ++
Sbjct: 872 LTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 912
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 121 bits (303), Expect = 5e-27
Identities = 106/348 (30%), Positives = 128/348 (36%), Gaps = 87/348 (25%)
Query: 732 GREQKKHHHHHHQQMQQAPAPVPQQP------------PPPPQQPPPPPPPQQQQ---QP 776
G++Q HH H Q + P PQ P P PQQ P P QQQQ QP
Sbjct: 261 GKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQP 320
Query: 777 PPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELP 836
P P PS P+Q A+ V+ P+ +P P P++P
Sbjct: 321 KKPSPQPSSPRQVKRAV-------------VVSPKEENKAAEP-----------PPPKIP 356
Query: 837 P----HLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSP 892
H P PP H P PP +P P + A LP PPA
Sbjct: 357 KIETTHPPLPPAHPPPDR-------KPPLAAALGEAEPPGPVD-ATDLPKVQIPPPAHPA 408
Query: 893 ALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPT---------- 942
+ Q P LP P PP + + ++ Q LQ + K + P+
Sbjct: 409 PVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQS-LQSMMKTEGPSYGALPPAYGP 467
Query: 943 ----PLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPP--PPPPPQ-PQPPPQQQHQPPPR 995
P P V + PPPP+PPPP PP PPP P P PPP PP
Sbjct: 468 PAHLPYHPHVYPPNPPPPPVPPPP-------ASFPPPAIPPPTPGYPPPPPTYNPNFPPP 520
Query: 996 PVHLQPMQFSTHIQQPPPPQG-------QQPPHPPPGQQPPPPQPAKP 1036
P L P TH P PP G PP PPG QPP P P P
Sbjct: 521 PPRLPP----THAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPP 564
Score = 95.9 bits (237), Expect = 2e-19
Identities = 93/334 (27%), Positives = 110/334 (32%), Gaps = 85/334 (25%)
Query: 742 HHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFI 801
+ Q QQ P P Q PP P P PQ QQ P PS PQQ P +
Sbjct: 258 YSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQ---- 313
Query: 802 ATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPA 861
Q P +P+ P PQP S+P + + VVSP
Sbjct: 314 --QQPAQQPKKPS-------------------------PQP---SSPRQVKRAVVVSP-- 341
Query: 862 LHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAP 921
+ N+AA PP P P + P P P P L + EPP P
Sbjct: 342 ----------KEENKAAE-PPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGP 390
Query: 922 PLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPS---------------- 965
+ L KVQ P P P+ Q P P PPPP PS
Sbjct: 391 --------VDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGE 442
Query: 966 ----VQQQLQQQPPP---------PPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPP 1012
+Q ++ + P PP P P PPP PV P F PP
Sbjct: 443 GYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPP-AIPP 501
Query: 1013 PPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSP 1046
P G PP P PPP P P H P
Sbjct: 502 PTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPP 535
Score = 83.2 bits (204), Expect = 2e-15
Identities = 96/357 (26%), Positives = 118/357 (33%), Gaps = 113/357 (31%)
Query: 711 SSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQP------------- 757
S S+ SE P+ K P ++Q+ Q + P+P P P
Sbjct: 291 SQPSQSSEPSQ-PQQKDPQQPAQQQQP------AQQPKKPSPQPSSPRQVKRAVVVSPKE 343
Query: 758 ------PPPPQQPP-----PPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPP-PFIATQV 805
PPPP+ P PP PP PPP P AA ++ PP P AT +
Sbjct: 344 ENKAAEPPPPKIPKIETTHPPLPPAH-------PPPDRKPPLAAALGEAEPPGPVDATDL 396
Query: 806 PVLE---PQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPAL 862
P ++ P P V P P LP P PP S ++ +
Sbjct: 397 PKVQIPPPAHPAPVHQP-------------PPLPHRPPPPPPSSYMTGMSTTSSYMSGEG 443
Query: 863 HNALPQQPSRPSNRAAALPPKPARP------PAVSPALTQTPLLPQPPMAQPPQVLLEDE 916
+ +L ALPP P P V P P +P PP + PP +
Sbjct: 444 YQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAI---- 499
Query: 917 EPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPP 976
PP P PP P P+ PPPP PP H PP
Sbjct: 500 PPPTPG----------------YPPPP--PTYNPNFPPPPPRLPPTH--------AVPPH 533
Query: 977 PPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQP 1033
PPP PP PP P P G QPP PPP PPP P
Sbjct: 534 PPPGLGLPPAS---YPP-----------------PAVPPGGQPPVPPP--IPPPGMP 568
Score = 82.0 bits (201), Expect = 4e-15
Identities = 91/377 (24%), Positives = 131/377 (34%), Gaps = 63/377 (16%)
Query: 812 LPGSVFDPIGHFTQPILHLPQPELPPHLP----QPPEHSTPPHLNQHAVVSPPALHNALP 867
+P V + I H + + ++P H P QPP P + P + + P
Sbjct: 242 VPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQV--------PQVQQSQP 293
Query: 868 QQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQ 927
Q S PS P +PA+ PA Q P P P + P QV P
Sbjct: 294 SQSSEPSQPQQKDPQQPAQQQ--QPA--QQPKKPSPQPSSPRQVKRAVVVSPK------- 342
Query: 928 MQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPH--PSVQQQLQQQPPPPPPPQPQPP 985
++ + +PP P +P ++ P PP PPP P + L + PP P P
Sbjct: 343 -----EENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLP 397
Query: 986 PQQQHQPP-PRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHH 1044
Q P P PVH PPP +PP PPP + +
Sbjct: 398 KVQIPPPAHPAPVH------------QPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQ 445
Query: 1045 SPRHH-KSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQ 1103
S + K++ S G L A P + + +PP V P ++
Sbjct: 446 SLQSMMKTEGPSYGALPPAYGP----PAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPP 501
Query: 1104 PQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIR 1163
P P + P ++P+ P PP+ P + P H P + P P +
Sbjct: 502 PTPG--------YPP--PPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVP 551
Query: 1164 PPEQ-----NAPPPGAP 1175
P Q PPPG P
Sbjct: 552 PGGQPPVPPPIPPPGMP 568
Score = 78.6 bits (192), Expect = 4e-14
Identities = 86/322 (26%), Positives = 115/322 (35%), Gaps = 81/322 (25%)
Query: 704 ESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHH--QQMQQAPAPVPQQ----- 756
+ S S SS+ + + + ++ P ++ KK +Q+++A P++
Sbjct: 289 QQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAA 348
Query: 757 -PPPP---------PQQPPPPPPPQQQ--------QQPPPPP------PPPSMPQQAAPA 792
PPPP P PP PPP ++ + PP P P +P A PA
Sbjct: 349 EPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPA 408
Query: 793 MKSSPPPFIATQVPVLEPQLPGSVFDP---------IGHFTQPILHLPQPELPPHLPQPP 843
PPP +P P P S + G Q + + + E P + PP
Sbjct: 409 PVHQPPP-----LPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPP 463
Query: 844 EHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQP 903
+ P HL H V PP P P P PP PPA+ P TP P P
Sbjct: 464 AYGPPAHLPYHPHVYPPN-----PPPPPVPP------PPASFPPPAIPP---PTPGYPPP 509
Query: 904 PMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPH 963
P P PP PP L V P P + S PPP +PP
Sbjct: 510 PPTYNPNF------PPPPP--------RLPPTHAVPPHPPPGLGLPPASYPPPAVPPGGQ 555
Query: 964 PSVQQQLQQQPPPPPPPQPQPP 985
P V PPP PP PP
Sbjct: 556 PPV--------PPPIPPPGMPP 569
Score = 70.9 bits (172), Expect = 8e-12
Identities = 78/289 (26%), Positives = 99/289 (34%), Gaps = 62/289 (21%)
Query: 928 MQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPH-PSVQQQLQQQPPPPPPPQ---PQ 983
+ LY Q Q++ TP Q Q PP L P P P VQQ Q P PQ PQ
Sbjct: 255 LDLYSQGKQQMPHHTPH------QLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQ 308
Query: 984 PPPQQQH--QPP--PRPVHLQPMQFSTHI----------QQPPPPQ--GQQPPHPPPGQQ 1027
P QQQ Q P P P P Q + +PPPP+ + HPP
Sbjct: 309 QPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPA 368
Query: 1028 PPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQ 1087
PPP P P P L + P H + Q L H+ PP
Sbjct: 369 HPPPDRKPPLAAALGEAEP----PGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPP-- 422
Query: 1088 NVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPF---SPSLRPEPPKH---PESIK 1141
P P + S + E + ++ E P + P +
Sbjct: 423 ----------------PPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYG 466
Query: 1142 APVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAP 1190
P HLP P + P + P + PP + PPP P P TP P
Sbjct: 467 PPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIP--------PPTPGYP 507
Score = 65.1 bits (157), Expect = 4e-10
Identities = 91/394 (23%), Positives = 118/394 (29%), Gaps = 137/394 (34%)
Query: 529 SQPQQNKPKKKEKDKKEKKKEKH-----------KRKEEVEENKKSKAKEPPPKKTKKNN 577
SQPQQ P++ + ++ ++ K KR V +++KA EPPP K K
Sbjct: 300 SQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIE 359
Query: 578 SSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHII 637
+++ + P P + KPP E + P+ D LP ++ H
Sbjct: 360 TTHPPLPPAHPPPDR-KPPLAAALGEAEPPGPV----------DATDLPKVQIPPPAHPA 408
Query: 638 QSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKG 697
+P P P + G S
Sbjct: 409 PVHQPPPLPHRP-------------------------------PPPPPSSYMTGMSTTSS 437
Query: 698 FSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQP 757
+ S E S +S S + P H +H H + P P
Sbjct: 438 YMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAH-----LPYHPHVY----------PPNP 482
Query: 758 PPPPQQPPPPPPPQQQQQPPP--PPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGS 815
PPPP PPPP PPP PPP P P PPP P P P
Sbjct: 483 PPPPV--PPPP----ASFPPPAIPPPTPGYP----------PPP------PTYNPNFP-- 518
Query: 816 VFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSN 875
PP PP H+ PPH PP L
Sbjct: 519 --------------------PPPPRLPPTHAVPPH-------PPPGL------------- 538
Query: 876 RAAALPPKPARPPAVSPALTQTPLLPQPPMAQPP 909
LPP PPAV P P PP PP
Sbjct: 539 ---GLPPASYPPPAVPPGGQPPVPPPIPPPGMPP 569
Score = 47.0 bits (110), Expect = 1e-04
Identities = 34/106 (32%), Positives = 39/106 (36%), Gaps = 12/106 (11%)
Query: 216 PPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQP---QPPPAPA-----PQP 267
PP P P P + P VPP P PPP P P PPP P P P
Sbjct: 462 PPAYGPPAHLP-YHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPP 520
Query: 268 VQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEP 313
PP A P P G+ + P + P +PP PP P
Sbjct: 521 PPRLPPTHAVPPHP---PPGLGLPPASYPPPAVPPGGQPPVPPPIP 563
Score = 45.1 bits (105), Expect = 5e-04
Identities = 30/119 (25%), Positives = 49/119 (41%), Gaps = 14/119 (11%)
Query: 244 PQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPI 303
P LQ PP + P PQ P QP QS P + PQ ++ +++ P P
Sbjct: 270 PHQLQQPPSLQPTPQVPQVQQSQPSQSSEP---SQPQQKDPQQPAQQQQPAQQPKKPSP- 325
Query: 304 HEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQ--------QHPAPEKSSKVSEQL 354
PS P + K + +E ++ +PP +P + HP P++ ++ L
Sbjct: 326 --QPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAAL 382
Score = 44.7 bits (104), Expect = 6e-04
Identities = 42/162 (25%), Positives = 55/162 (33%), Gaps = 42/162 (25%)
Query: 192 GVSTVPNTT--QASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQT-PVMTVVPPQPLQ 248
G +P+ T Q PP Q P P P VQ + P + P Q P QP Q
Sbjct: 261 GKQQMPHHTPHQLQQPPSLQ-PTPQVPQVQQS-QPSQSSEPSQPQQKDPQQPAQQQQPAQ 318
Query: 249 TPPPVPPQP---------------------QPPPAPAPQPVQSHPPIIAATPQPVKTKKG 287
P PQP +PPP P+ +HPP+ A P P +
Sbjct: 319 QPKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPL 378
Query: 288 VKRKADTTTPTTID----------------PIHEPPSLPPEP 313
+ P +D P+H+PP LP P
Sbjct: 379 AAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRP 420
Score = 44.3 bits (103), Expect = 8e-04
Identities = 29/107 (27%), Positives = 35/107 (32%), Gaps = 27/107 (25%)
Query: 205 PPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPA 264
PP + P PPP P P P P+ PP P + PP P PPP
Sbjct: 490 PPASFPPPAIPPPTPGYPPPPPTYNPNF----------PPPPPRLPPTHAVPPHPPPGLG 539
Query: 265 PQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPP 311
P PP + QP + P PP +PP
Sbjct: 540 LPPASYPPPAVPPGGQP-----------------PVPPPIPPPGMPP 569
Score = 41.6 bits (96), Expect = 0.005
Identities = 26/84 (30%), Positives = 35/84 (41%), Gaps = 6/84 (7%)
Query: 183 RKETGTAKPGVSTVPN--TTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMT 240
++E A+P +P TT PP P PP A P D P +
Sbjct: 342 KEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDA-TDLPKVQ 400
Query: 241 VVPPQ---PLQTPPPVPPQPQPPP 261
+ PP P+ PPP+P +P PPP
Sbjct: 401 IPPPAHPAPVHQPPPLPHRPPPPP 424
Score = 41.2 bits (95), Expect = 0.007
Identities = 32/93 (34%), Positives = 35/93 (37%), Gaps = 13/93 (13%)
Query: 191 PGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHP-FPAVTPDLIVQTPVMTVVPPQP--- 246
P VP + PP P P PP T +P FP P L P VPP P
Sbjct: 482 PPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRL----PPTHAVPPHPPPG 537
Query: 247 LQTPPPVPPQPQPP-----PAPAPQPVQSHPPI 274
L PP P P P P P P P PP+
Sbjct: 538 LGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPV 570
Score = 38.9 bits (89), Expect = 0.034
Identities = 39/150 (26%), Positives = 58/150 (38%), Gaps = 32/150 (21%)
Query: 209 QTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVV----PPQPL--------QTPPPVPPQ 256
+ P P P ++ T P P P + P+ + PP P+ Q PPP P
Sbjct: 349 EPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPA 408
Query: 257 P--QPPP---APAPQPVQSHPPIIAATPQPVKTK--KGVKRKADTTTPT--TIDPIHEPP 307
P QPPP P P P S+ ++ T + + + ++ T P+ + P + PP
Sbjct: 409 PVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPP 468
Query: 308 S-LPPEPKTTKLGQRRESSRPVKPPKKDVP 336
+ LP P P PP VP
Sbjct: 469 AHLPYHPHV----------YPPNPPPPPVP 488
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 119 bits (299), Expect = 2e-26
Identities = 201/920 (21%), Positives = 330/920 (35%), Gaps = 131/920 (14%)
Query: 476 PTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNK 535
P + A ++ +S + S S ++ E +L+E + + Q+AA+ Q
Sbjct: 13 PEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERR------QIAAVMSRAQGL 66
Query: 536 PKKKEKDKKEKKKEKHKRKE-EVEENKKSKAKEPPPKKTKKNNSSNSNVSK--KEPAPMK 592
PK + H+++E + K + P P + + S S + + +
Sbjct: 67 PKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLP 126
Query: 593 SKPPPTYESEEEDKCKPMSYEEKRQLS----LDINKLPGEKLGRVVH------IIQSREP 642
+ P T +E + E K + ++N L + VV+ +I E
Sbjct: 127 GRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNAL--SAVSSVVNKFNPFDLISDSEA 184
Query: 643 SLKNSNPDEIEIDFETLKPSTLRE--LERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSS 700
S + + + + E KP + + L++ + K++ P D + K SS
Sbjct: 185 SQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGR---DPLQQDGTPKSISS 241
Query: 701 SESE-------SSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPV 753
+ E + + ++ +T+ A K + R Q K + + P
Sbjct: 242 QQPEKIKSQPPGTGKPIQGPTQTPQTDHA-KLPLQRDASRPQTKQADIVRGESVKPSLPS 300
Query: 754 PQQPPPPPQQPPPPPPPQQQ----QQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLE 809
P + PP QQP P PP QQ + P P PP+ P + P T P ++
Sbjct: 301 PSK--PPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP----GTVKPPVQ 354
Query: 810 PQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQ 869
P PG+ P QP+ P PP E + A+ PP + QQ
Sbjct: 355 P--PGTTKPP----AQPL----GPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQ 404
Query: 870 --PSRPSNRAAALP-PKPARP----PAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPP 922
P++P + P P +P PA +P T+TP+ P P Q P
Sbjct: 405 PGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ-------QAGPG 457
Query: 923 LTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQP 982
TS QQ +PP+ L K PPP P P P QQ +PP P
Sbjct: 458 KTS------AQQTGPTKPPSQLPGPAK----PPPQQPGPAKPPPQQPGSAKPPSQQPGST 507
Query: 983 QPPPQQQHQPPPRPVHLQPMQFSTHIQQP--PPPQGQQP-PHPPPGQQPPPP-------Q 1032
+PPPQQ P +P QP QQP P QQP P P QQ P +
Sbjct: 508 KPPPQQ--PGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK 565
Query: 1033 PAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSP-------- 1084
P +P V P + P + L + L++H P+ + F + T
Sbjct: 566 PLQPPTVSPSAKQP-PSQGLPKTICPLCNT-TELLLHVPEKANFNTCTECQTTVCSLCGF 623
Query: 1085 -PQQNVQPKKQEL-------------RAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLR 1130
P ++ K+ L A PQP + S + +S P
Sbjct: 624 NPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTS 683
Query: 1131 PEPPKHPESIKAPVHLPQRPE---MKPVDVGRPVIR---PPEQNAPPPGAPDKDKQ--KQ 1182
P+ P+ + P++P +P G P + PPE ++ AP K+ +
Sbjct: 684 PKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSE 743
Query: 1183 EPKTPVAPKKDLKIKNMGSWASLVQK-----HPTTPSSTAKSSSDSFEQFRRAAREKEER 1237
+ K PVA K + K + LV P PSS +S ++ + K +
Sbjct: 744 QDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEE----KTTPPLKTDS 799
Query: 1238 EKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQ 1297
K ++ EK + R D + + E ++Q Q+++E ++ Q
Sbjct: 800 AKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQ 859
Query: 1298 QQQAAAVAAAATPQAQSSQP 1317
+ + A P+ + P
Sbjct: 860 TKMSPKPDAKPMPKGSPTPP 879
Score = 95.5 bits (236), Expect = 3e-19
Identities = 249/1201 (20%), Positives = 398/1201 (33%), Gaps = 180/1201 (14%)
Query: 177 KGRGRGR---KETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHP-FPAVTPDL 232
K +G GR ++ GT K S P + S PP T P P T H P
Sbjct: 221 KQQGPGRDPLQQDGTPKSISSQQPEKIK-SQPPGTGKPIQGPTQTPQTDHAKLPLQRDAS 279
Query: 233 IVQTPVMTVV------PPQPLQTPPPVP-PQPQPPPAPAPQPVQSHPPIIAATPQPVKTK 285
QT +V P P + PP+ P P PPA P +S P QP
Sbjct: 280 RPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLT 339
Query: 286 KGVKRKADTTTPTTIDP-IHEPPSL---PPEPKTTKLGQRRESSRPVKPPKKDVPDS--- 338
K + ++ T P P +PP+ P +P + G + SS P P
Sbjct: 340 KPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGK 399
Query: 339 --QQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKH 396
Q P P K ++Q+ + ++ + A P PV G
Sbjct: 400 TPAQQPGPAKPP--TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPG---------- 447
Query: 397 PMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAK 456
I ++ AQ+ G PP A Q ++
Sbjct: 448 -----KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502
Query: 457 MPDE----PEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLA 512
P P++P A SP P TK PPS S+ S+ S S ++ + ++
Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTK---PPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS 559
Query: 513 EL--QEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPP 570
+ + L+ +A P Q PK + H P
Sbjct: 560 QTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLH-----------------VP 602
Query: 571 KKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKL 630
+K N + + P P +E C ++ + KR L D+ +P
Sbjct: 603 EKANFNTCTECQTTVCSLCGF--NPNPHLTEVKEWLC--LNCQMKRALGGDLAPVPSSPQ 658
Query: 631 GRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIA 690
++ + ++ S+P + P ++ ++ K+ P K +
Sbjct: 659 PKLKTAPVTTTSAVSKSSPQP-----QQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLH 713
Query: 691 GSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAP 750
GS K E++S S+ P K+ EQ K
Sbjct: 714 GSPSAKAKQPPEADSLSK--------------PAPPKEPSVPSEQDK------------- 746
Query: 751 APVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEP 810
APV P P+ P P PS Q+ K++PP + T +
Sbjct: 747 APVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPP--LKT-----DS 799
Query: 811 QLPGSVFDPIGHFTQPI--LHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQ 868
P F P G P +P+P + P S+ + V P Q
Sbjct: 800 AKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQ--VDP-------VQ 850
Query: 869 QPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQM 928
+ P + PKP P P + TP P+P Q + ++ P P S +
Sbjct: 851 KKEEPKKAQTKMSPKPDAKP--MPKGSPTPPGPRPTAG---QTVPTPQQSPKPQEQSRRF 905
Query: 929 QLYLQQL---QKVQPPTPLLP--------SVKVQSQPPPPLPPPPHPSVQQQ------LQ 971
L L + K QP TP + SQ + P Q ++
Sbjct: 906 SLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMK 965
Query: 972 QQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTH--IQQPPPPQGQQPPHPPPGQQPP 1029
Q P P PP Q PP+ Q PP P P++ T + P+ +Q P +
Sbjct: 966 QAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEK 1025
Query: 1030 PPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNV 1089
P P K + S L ++P P P ++ + PP N
Sbjct: 1026 KPPPIKDSK------SLTAEPQKAVLPTKLEKSPKPEST-CPLCKTELNIGSKDPPNFNT 1078
Query: 1090 QPK-KQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSL---RPEPPKHPESIKAPVH 1145
+ K ++ P P + +E + S L R PP
Sbjct: 1079 CTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPP----------- 1127
Query: 1146 LPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASL 1205
P P+ P+ V P ++ A PP KQ+QE KT K+K S
Sbjct: 1128 APSGPKASPMPV--PTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLS---- 1181
Query: 1206 VQKHPTTPSSTAKSSSDSFEQFRRAAREKE----EREKALKAQAEHAEKEKERLRQERMR 1261
++K P ++ K E+ + +A +++ E +K + + + +EK+ L +E+
Sbjct: 1182 MEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKP 1241
Query: 1262 SREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSML 1321
+ ED+ L +A+ + E EQ+ + Q Q +++ A T Q + QPQ+ +
Sbjct: 1242 TPEDKKLLPEAKTSAPE-----EQKHDLLKSQVQIAEEKLEGRVAPKTVQ-EGKQPQTKM 1295
Query: 1322 D 1322
+
Sbjct: 1296 E 1296
Score = 88.2 bits (217), Expect = 5e-17
Identities = 250/1307 (19%), Positives = 451/1307 (34%), Gaps = 226/1307 (17%)
Query: 184 KETGTAKPGVSTVPNTTQASTPP-----QTQTPQPNPPPVQATPHPFP-AVTPDLIVQTP 237
++TG+ KP S P + PP Q P P PP Q P P A P L Q+P
Sbjct: 374 QQTGSEKPS-SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGL--QSP 430
Query: 238 VMTVVPPQ-PLQTPPP--VPPQ-------------PQPPPAPAPQPVQSHPPIIAATPQP 281
P + P+Q P P +P Q P PP+ P P + P QP
Sbjct: 431 AKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQ------QP 484
Query: 282 VKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQH 341
K ++ P+ +PP P P Q + P + P P +QQ
Sbjct: 485 GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQP 544
Query: 342 PAPEKSSKVSEQLKCCSGILKEMFAKKHAAYA-WPFYKPVDVEALGLHDYCDIIKHPMDM 400
+ S++ S + +G K + + A P + + L + +++ H +
Sbjct: 545 SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEK 604
Query: 401 STIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDH-----EVVAMARKLQDVFEMRFA 455
+ + E + + S C +NP H E + + +++ A
Sbjct: 605 ANFNTCTECQ------------TTVCSLC-GFNPNPHLTEVKEWLCLNCQMKRALGGDLA 651
Query: 456 KMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQ 515
+P P+ + A T V+ S + D+ D S+ ++ L
Sbjct: 652 PVPSSPQPKL----KTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLV 707
Query: 516 EQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKK 575
+Q A QP + K KE + K V ++K + K P
Sbjct: 708 KQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLV 767
Query: 576 NNSS------------NSNVSKKEPAPMK---SKP----PPTYE--SEEEDKCKPMSYEE 614
++SS S +K P+K +KP PPT E S + K P +
Sbjct: 768 SSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASD 827
Query: 615 KRQLSLDINKLPGEKLGRVVHIIQSREP----SLKNSNPDEIEIDFETLKPSTLRELERY 670
+ +S + +V + + EP + + PD + + P R
Sbjct: 828 SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887
Query: 671 VTSCLRKKRKP--QAEKVDVIAGS-----------------SKMKGFSSS-ESESSSESS 710
++ KP Q+ + + GS K+ GF +S S++S+ S
Sbjct: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947
Query: 711 SSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAP--------------APVPQQ 756
++ ++ P + K P Q + QAP AP ++
Sbjct: 948 TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK 1007
Query: 757 PPPPPQQPPPPPPPQQQQQPPPPPPPPSM---PQQAAPAMKSSPPPFIATQVPVLEPQLP 813
P +Q P + +++PPP S+ PQ+A K P + P+ + +L
Sbjct: 1008 LEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELN 1067
Query: 814 GSVFDPIGHFT-----QPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQ 868
DP T + +L PHL + E Q A+ +P
Sbjct: 1068 IGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPP 1127
Query: 869 QPSRPSNRAAALPPK-PARPPAVSPALTQTPLLPQPPMAQPPQVLLE------DEEPPAP 921
PS P +P + ++ AV P + Q + +V+LE E P
Sbjct: 1128 APSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPP 1187
Query: 922 PLTSMQMQ----------LYLQQLQKVQPPTPLLP-SVKVQSQPPPPLPPPPHPSVQQQL 970
+T+ Q Q LQ+ + + L+P K++S+ PL L
Sbjct: 1188 MVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPL-----------L 1236
Query: 971 QQQPPPP------PPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPP 1024
+++ P P P + P +Q+H V + + + +G+QP
Sbjct: 1237 EEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKME 1296
Query: 1025 G---------------------QQPPPPQPAKPQQV------------------IQHHHS 1045
G +QP PP AKP QV Q S
Sbjct: 1297 GLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKS 1356
Query: 1046 PRHHKSDPYS----TGHLREAPSPLMIHSPQM---SQFQSLTHQSPPQQNVQPKKQELRA 1098
P+ YS + L E PS + + + S + +S P K E
Sbjct: 1357 PQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTV 1416
Query: 1099 ASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVG 1158
S+++ Q + E+ +++P S PE PK E ++ E + +
Sbjct: 1417 LSILEAQASTLADEKSEK----KTQPHEVS--PEQPKDQEKTQS------LSETLEITIS 1464
Query: 1159 RPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKN--MGSWASLVQKHPTTPSST 1216
I+ ++ KD K++ + + KD K K+ + + + + + S+
Sbjct: 1465 EEEIKESQEER-------KDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESS 1517
Query: 1217 AKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAH 1276
+S ++ RR + ++ + ++ + +E++ +R++ + DEDA +
Sbjct: 1518 ESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDA---SGSED 1574
Query: 1277 EEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQ 1323
+E R Q ++ E Q++++ + A + + + + +D+
Sbjct: 1575 DEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDE 1621
Score = 87.8 bits (216), Expect = 6e-17
Identities = 193/915 (21%), Positives = 302/915 (33%), Gaps = 191/915 (20%)
Query: 431 KYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAP---PSSSD 487
K+NP D +++ + Q+ + + E +P + P P K + P
Sbjct: 172 KFNPFD--LISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDP 229
Query: 488 SSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNK----PKKKEKDK 543
D + S SS Q+ +++ Q + + +Q Q P +++ +
Sbjct: 230 LQQDGTPKSISS---------QQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASR 280
Query: 544 KEKKKEKHKRKEEVEENKKSKAKEPPPKKTK-KNNSSNSNVSKKEPAPMK--------SK 594
+ K+ R E V+ + S +K P + T K + K +P P K +K
Sbjct: 281 PQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTK 340
Query: 595 PPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEI 654
P + +P + L K P ++ G S +PS + P +
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTG-------SEKPSSEQPGPKALAQ 393
Query: 655 D-----FETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSK----MKGFSSSESES 705
+P + + V + ++P + G +K G ++
Sbjct: 394 PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQ 453
Query: 706 SSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQA--PAPVPQQPPPPPQQ 763
+ +S + T+ + P +Q QQ A P+ P PPPQQ
Sbjct: 454 AGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQ 513
Query: 764 PPPPPPPQQQ--------QQPPPPPPPPSMPQQAAPAMKSSPPPFIAT------QVPVLE 809
P P P QQ QQP P P A P+ + S P T Q P +
Sbjct: 514 PGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS 573
Query: 810 PQ--------LPGSVFDPIGHFTQPILHLPQP-------------------ELPPHLPQ- 841
P LP ++ P+ + T+ +LH+P+ PHL +
Sbjct: 574 PSAKQPPSQGLPKTIC-PLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEV 632
Query: 842 -------------------PPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALP- 881
P S P L V + A+ + PQ P + S + A P
Sbjct: 633 KEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQ-PQQTSPKKDAAPK 691
Query: 882 ------PKPARPPAVSPALTQTPLLPQPPMA---QPPQV--LLEDEEPPAPPLTSMQMQL 930
P+P +PP L + P L P A QPP+ L + P P + S Q +
Sbjct: 692 QDLSKAPEPKKPPP----LVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKA 747
Query: 931 YL-----QQLQKVQPPTPL-----------LPSVKVQSQPPPPLPPPPHPSVQQQLQQQP 974
+ +Q + V+P T L +PS KVQSQ PP + Q P
Sbjct: 748 PVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFP 807
Query: 975 PP------------PPP---------PQPQPPPQQQHQPPPRPVHLQPMQFSTHIQ---- 1009
P P P P P + Q Q P +P + T +
Sbjct: 808 PTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD 867
Query: 1010 -QPPPPQGQQPPHPPP--GQQPPPPQPA-KPQQVIQHHH--------SPRHHKSDPYSTG 1057
+P P PP P P GQ P PQ + KPQ+ + +P+ + P T
Sbjct: 868 AKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETV 927
Query: 1058 HLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHS 1117
+ I S Q S S Q P P +A + QP
Sbjct: 928 TGKLFGFGASIFS-QASNLISTAGQPGPHSQSGPGAPMKQAPAPSQP------------- 973
Query: 1118 PIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDK 1177
P + P S P P +K P +++P P ++ E PP D
Sbjct: 974 PTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDS 1033
Query: 1178 DKQKQEPKTPVAPKK 1192
EP+ V P K
Sbjct: 1034 KSLTAEPQKAVLPTK 1048
Score = 67.0 bits (162), Expect = 1e-10
Identities = 59/197 (29%), Positives = 78/197 (39%), Gaps = 37/197 (18%)
Query: 753 VPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQL 812
+ QPPPPP PPPPPP PPPPPPPP +P +P P + PV
Sbjct: 2401 ISAQPPPPPPPPPPPPP------PPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTAT- 2453
Query: 813 PGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSR 872
+FD + + L LP + + +PP + P+ S
Sbjct: 2454 --PLFDAVTTLETTAV-LRSNGLP--------------VTRICTTAPPPVP---PKPSSI 2493
Query: 873 PSNRAAALPPKPARPP-AVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLT-SMQMQL 930
PS P+P++PP A P + Q P Q P P +P LT SM + L
Sbjct: 2494 PSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHP-------KPTGLSLTSSMTLNL 2546
Query: 931 YLQQLQKVQPPT-PLLP 946
K+ PT PL P
Sbjct: 2547 VTSADYKLPSPTSPLSP 2563
Score = 60.5 bits (145), Expect = 1e-08
Identities = 60/241 (24%), Positives = 87/241 (36%), Gaps = 46/241 (19%)
Query: 748 QAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQ----AAPAMKSS------- 796
Q P P P PPPPP PPPPPPP PP P P +P++ A+P ++
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPP---LPPPTSPKPTILPKKKLTVASPVTTATPLFDAVT 2460
Query: 797 -------------PPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPP 843
P I T P P P S+ P G H P+P PP P+P
Sbjct: 2461 TLETTAVLRSNGLPVTRICTTAPPPVPPKPSSI--PSG---LVFTHRPEPSKPPIAPKPV 2515
Query: 844 EHSTP----------PHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPA 893
P P ++ S L+ PS + P P S +
Sbjct: 2516 IPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKS 2575
Query: 894 LTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQ 953
LT+T ++ + P + + + +TS + + L V+P ++P V
Sbjct: 2576 LTETYVV----ITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEI 2631
Query: 954 P 954
P
Sbjct: 2632 P 2632
Score = 60.1 bits (144), Expect = 1e-08
Identities = 52/174 (29%), Positives = 64/174 (36%), Gaps = 33/174 (18%)
Query: 206 PQTQTPQPNPP--PVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAP 263
P +Q P +P + A P PF + I P PP P PPP PP P PPP P
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQP-----PPPPPPPPPPPPPPPPPPPPP 2426
Query: 264 APQPVQSHP------------PIIAATP--QPVKTKKGVKRKADTTTPTTIDPIHEPPSL 309
P P P P+ ATP V T + P T PP +
Sbjct: 2427 LPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPV 2486
Query: 310 PPEPKTTKLG----QRRESSRPVKPPKKDVPD--------SQQHPAPEKSSKVS 351
PP+P + G R E S+P PK +P + HP P S S
Sbjct: 2487 PPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTS 2540
Score = 59.7 bits (143), Expect = 2e-08
Identities = 58/217 (26%), Positives = 75/217 (34%), Gaps = 58/217 (26%)
Query: 939 QPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVH 998
+ P LPS P P P S + QPPPPPPP P PPP PPP
Sbjct: 2370 EKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPP-----PPP---- 2420
Query: 999 LQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGH 1058
PPPP PP PPP P P K V
Sbjct: 2421 ------------PPPP----PPLPPPTSPKPTILPKKKLTV------------------- 2445
Query: 1059 LREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSP 1118
SP+ +P +L + + N P + A P V K I S
Sbjct: 2446 ----ASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTA-----PPPVPPKPSSIPSG 2496
Query: 1119 II---RSEPFSPSLRPEP--PKHPESIKAPVHLPQRP 1150
++ R EP P + P+P P+ P + + P + +P
Sbjct: 2497 LVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKP 2533
Score = 55.8 bits (133), Expect = 3e-07
Identities = 78/320 (24%), Positives = 109/320 (34%), Gaps = 78/320 (24%)
Query: 883 KPARP-PAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPP 941
KPA P+ SP+++ P P+P + PP PP PP
Sbjct: 2371 KPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP-----------------PP 2413
Query: 942 TPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQP---PPQQQHQPPPRPVH 998
P PPPP PPP PP PPP P+P P ++ P
Sbjct: 2414 PP---------PPPPPPPPP------------PPLPPPTSPKPTILPKKKLTVASPVTTA 2452
Query: 999 LQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQV---IQHHHSPRHHKSDPYS 1055
T ++ + P PPP P KP + + H P K
Sbjct: 2453 TPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPP--- 2509
Query: 1056 TGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKI 1115
AP P++ PQ+ T Q P + +P L ++ + LV + K+
Sbjct: 2510 -----IAPKPVI---PQL----PTTTQKPTDIHPKPTGLSLTSSMTLN---LVTSADYKL 2554
Query: 1116 HSPIIRSEPFSPSLRPEPPKHPESIK---APVHLPQRPEMKPVDVGRPVIRPPEQ--NAP 1170
SP + P SP P+ +S+ + LP P G P Q +
Sbjct: 2555 PSP---TSPLSPHSNKSSPRFSKSLTETYVVITLPSEP-------GTPTDSSASQAITSW 2604
Query: 1171 PPGAPDKDKQKQEPKTPVAP 1190
P G+P KD EP V P
Sbjct: 2605 PLGSPSKDLVSVEPVFSVVP 2624
Score = 53.9 bits (128), Expect = 1e-06
Identities = 126/625 (20%), Positives = 224/625 (35%), Gaps = 110/625 (17%)
Query: 141 KPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTT 200
KP D+V + A K ++P+ + + QA+ + +T +AKP S P
Sbjct: 761 KPTTDLVSSSSATTK------PDIPSSKVQS---QAEEKTTPPLKTDSAKPSQSFPPTGE 811
Query: 201 QASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQT-PVMTVVPPQPLQTPPPVPPQPQP 259
+ S P+P + HP P+ Q PV P+ QT P +P
Sbjct: 812 KVSPFDSKAIPRPASDS-KIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKP 870
Query: 260 PPAPAPQPVQSHPPIIAATPQPVKTKKGVK--RKADTTTPTTIDPIHEPPSLPPEPKTTK 317
P +P P P P P ++ K + R+ + D P+ P E T K
Sbjct: 871 MPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGK 930
Query: 318 L------------------GQ------------RRESSRPVKPPKKDVP---DSQQHPAP 344
L GQ +++ P +PP P Q PAP
Sbjct: 931 LFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAP 990
Query: 345 EKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEAL--GLHDYCDIIKHPMDMST 402
KS V ++ K + E A++ P K + E + D + P +
Sbjct: 991 AKSIPVKKETKAPAAEKLEPKAEQA-----PTVKRTETEKKPPPIKDSKSLTAEP-QKAV 1044
Query: 403 IKSKLEARE----------------YRDAQEFG--ADVRLMFSNCYKYNPPDHEVV---- 440
+ +KLE +D F + + N +NP H
Sbjct: 1045 LPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEW 1104
Query: 441 ---------AMARKLQDVFEMRFAKM-PDEPEEPVVAVSS---PAVPPPTKVVAPPSSSD 487
A++ +L D+ +M A P PV SS AVPP K+V
Sbjct: 1105 LCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEV 1164
Query: 488 SSSDSSSDSDSSTDDSEEERAQRLA---ELQEQLKAVHEQLAALSQPQQNKPKKKEKDKK 544
+ + + E+ + + QE+ K ++ +AL Q ++ P++K+ +
Sbjct: 1165 KTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASAL-QEKKPLPEEKKLIPE 1223
Query: 545 EKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEE 604
E+K ++K +EE K+P P+ K + ++ +++ + E + E
Sbjct: 1224 EEKIRSEEKKPLLEE------KKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLE 1277
Query: 605 DKCKPMSYEEKRQLSLDINKLPG-------EKLGRVVHIIQSREPSLKNSNPDEIEIDFE 657
+ P + +E +Q + LP ++ + I+ + + PD++E
Sbjct: 1278 GRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPG-- 1335
Query: 658 TLKPSTLRELERYVTSCLRKKRKPQ 682
K T +E ++ TS ++ + PQ
Sbjct: 1336 --KEKTEKEDDKSDTSSSQQPKSPQ 1358
Score = 51.2 bits (121), Expect = 7e-06
Identities = 47/174 (27%), Positives = 71/174 (40%), Gaps = 23/174 (13%)
Query: 174 VQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQ--PNPPPVQATPHPFPAVTPD 231
+Q+ + G +T +PG +P Q + P +T Q P PP Q P PA P
Sbjct: 427 LQSPAKAPGPTKTPVQQPGPGKIP--AQQAGPGKTSAQQTGPTKPPSQL---PGPAKPP- 480
Query: 232 LIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRK 291
P QP PP P QP P+ QP + PP P ++ K
Sbjct: 481 -----------PQQPGPAKPP-PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK 528
Query: 292 ADTTTPTTIDPIHEPPS--LPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPA 343
+ P + P + PS P ++TK + S +P++PP P ++Q P+
Sbjct: 529 PPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS-PSAKQPPS 581
Score = 50.1 bits (118), Expect = 1e-05
Identities = 48/179 (26%), Positives = 65/179 (36%), Gaps = 14/179 (7%)
Query: 176 AKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATP-HPF-PAVTP--D 231
A+ G + + G AKP T + P T P PP P P PA P
Sbjct: 316 AQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQ 375
Query: 232 LIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRK 291
+ P P+ L PP V P P PA P Q TP+P+ + G++
Sbjct: 376 TGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQ-----VGTPKPLAQQPGLQSP 430
Query: 292 ADTTTPTTIDPIHEP-PSLPPEPKTTKLGQRRESSRPVKPPKK---DVPDSQQHPAPEK 346
A PT P+ +P P P + + + P KPP + Q P P K
Sbjct: 431 AKAPGPTK-TPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAK 488
Score = 47.4 bits (111), Expect = 1e-04
Identities = 42/147 (28%), Positives = 55/147 (37%), Gaps = 17/147 (11%)
Query: 175 QAKGRGR-GRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLI 233
Q G G+ ++TG KP P+ P Q P P PP Q P A P
Sbjct: 452 QQAGPGKTSAQQTGPTKP-----PSQLPGPAKPPPQQPGPAKPPPQ---QPGSAKPPS-- 501
Query: 234 VQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKAD 293
Q P T PPQ P P QP P+ QP + P +P ++ K +
Sbjct: 502 -QQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ 560
Query: 294 TTT-----PTTIDPIHEPPSLPPEPKT 315
T + P T+ P + P PKT
Sbjct: 561 TGSGKPLQPPTVSPSAKQPPSQGLPKT 587
Score = 46.6 bits (109), Expect = 2e-04
Identities = 120/597 (20%), Positives = 213/597 (35%), Gaps = 93/597 (15%)
Query: 165 PTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHP 224
PT E + ++ +AK ++ K V + P+T P Q
Sbjct: 1241 PTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQP---QTKMEG 1297
Query: 225 FPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQ--------SHPPIIA 276
P+ TP + P + +T + QPQPP P V+
Sbjct: 1298 LPSGTPQSL---------PKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDT 1348
Query: 277 ATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVP 336
++ Q K+ +G+ ++ + P +P + K G +++S ++ P
Sbjct: 1349 SSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSF-----SQESSP 1403
Query: 337 DSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKH 396
S A +S+ +S S + E KK + +P D E K
Sbjct: 1404 SSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQE-----------KT 1452
Query: 397 PMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAK 456
T++ + E +++QE D S + DH+ K + V ++ +
Sbjct: 1453 QSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHK-----EKSEFVDDITTRR 1507
Query: 457 MP-DEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSE-------EERA 508
P D EE + +SP P K SS S DS S ++ + E A
Sbjct: 1508 EPYDSVEESSESENSPV--PQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSA 1565
Query: 509 QRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEP 568
A E + + QL +S +++ K++ K K + KH+R +KS
Sbjct: 1566 DEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRL-----TRKSSTSID 1620
Query: 569 PPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGE 628
+ + + + E +K + + ESEE +R ++++N +
Sbjct: 1621 EDAGRRHSWHDEDDEAFDESPELKYRETKSQESEE--LVVTGGGGLRRFKTIELNSTIAD 1678
Query: 629 KLGRVVHIIQSREPSLKNSN---PDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEK 685
K S E S K ++ +E E++ E+L S + + + E
Sbjct: 1679 K--------YSAESSQKKTSLYFDEEPELEMESLTDS--------------PEDRSRGE- 1715
Query: 686 VDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHH 742
GSS + S + S + SS D EDS++ S KKG +++K H H
Sbjct: 1716 -----GSSSLHASSFTPGTSPTSVSSLD-EDSDSS---PSHKKGESKQQRKARHRPH 1763
Score = 44.7 bits (104), Expect = 6e-04
Identities = 45/154 (29%), Positives = 60/154 (38%), Gaps = 28/154 (18%)
Query: 874 SNRAAALPPKPARPPAVSPAL---TQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQL 930
S ++LP KP RP S +L Q P P PP PP PP PP TS + +
Sbjct: 2380 SPSVSSLPAKP-RPFFRSSSLDISAQPPPPPPPPPPPPPPP-PPPPPPPLPPPTSPKPTI 2437
Query: 931 YLQQLQKVQPP----TPL-----------------LPSVKVQSQPPPPLPPPPH--PSVQ 967
++ V P TPL LP ++ + PPP+PP P PS
Sbjct: 2438 LPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGL 2497
Query: 968 QQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQP 1001
+ P PP P+P Q +P + P
Sbjct: 2498 VFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHP 2531
Score = 44.3 bits (103), Expect = 8e-04
Identities = 66/298 (22%), Positives = 117/298 (39%), Gaps = 23/298 (7%)
Query: 462 EEPVVAVSSPAVPPPTKVVAPPSSSDSSSD----SSSDSDSSTD-DSEEERAQRLAELQE 516
EEP + + S P + SSS +S +S S SS D DS+ + + E ++
Sbjct: 1695 EEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQ 1754
Query: 517 QLKAVHEQLAALSQPQQNKPKKKE---------KDKKEKKKEKHKRKEEVEENKKSKAKE 567
Q KA H L ++ +++E + +K+++ E+ +RK +++KK K +
Sbjct: 1755 QRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDEL 1814
Query: 568 PPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPG 627
++ ++ + SN+S E A + E EE + Y + + ++
Sbjct: 1815 RAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEGFEISP 1874
Query: 628 EKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRK----PQA 683
EK+ V + + S DE I + L+ E + K K P A
Sbjct: 1875 EKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYEEMMHKTHKYKAFPAA 1934
Query: 684 EKVDVIAGSSKMKGFSSSES---ESSSESSSSDSEDSE--TEMAPKSKKKGHPGREQK 736
+ D + + G E ES E + + S D T ++ GREQK
Sbjct: 1935 NERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEENGFMQQKGREQK 1992
Score = 43.5 bits (101), Expect = 0.001
Identities = 61/288 (21%), Positives = 110/288 (38%), Gaps = 42/288 (14%)
Query: 1077 QSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKH 1136
Q L+ SPP+ +P E+ +S ++ V + SP + P SP P K
Sbjct: 3579 QYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPL---SPGKA 3635
Query: 1137 PESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQ----EPKTPVAPKK 1192
ES P P P D+ + P+ PP +P K Q +PK P++P
Sbjct: 3636 LESAFVPYEKPL-----PDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPK-PLSPTA 3689
Query: 1193 DLKIK------------------NMGSWASLVQKHPTTPSSTAKSSSDS-FEQFRRAARE 1233
D + + G+ + + P P + + S F +R
Sbjct: 3690 DESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNPPPEEISTGTQSTFSTMGTVSRR 3749
Query: 1234 K------EEREKALK---AQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEA-RRRQ 1283
+ R K L+ + + E+E +LR+++ E+E ++ R E RR+
Sbjct: 3750 RICRTNTMARAKILQDIDRELDLVERESAKLRKKQAELDEEEKEIDAKLRYLEMGINRRK 3809
Query: 1284 EQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKR 1331
E ++R+++++ Q A + SS + ++ Q + R R
Sbjct: 3810 EALLKEREKRERAYLQGVAEDRDYMSDSEVSSTRPTRIESQHGIERPR 3857
Score = 37.0 bits (84), Expect = 0.13
Identities = 37/124 (29%), Positives = 51/124 (41%), Gaps = 27/124 (21%)
Query: 237 PVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTT 296
P + PP Q P P+P Q P P Q TP+ + +++ K K+
Sbjct: 203 PEGIIKPPLQQQPPKPIPKQQGPGRDPLQQD---------GTPKSISSQQPEKIKSQ--P 251
Query: 297 PTTIDPIHEPPSLPPEPKTTKLGQRRESSRP------------VKP--PKKDVPDSQQHP 342
P T PI + P+ P+ KL +R++SRP VKP P P QQ P
Sbjct: 252 PGTGKPI-QGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQ-P 309
Query: 343 APEK 346
P K
Sbjct: 310 TPGK 313
Score = 35.0 bits (79), Expect = 0.49
Identities = 36/111 (32%), Positives = 48/111 (43%), Gaps = 4/111 (3%)
Query: 1222 DSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARR 1281
D +Q RE E EK +K Q E E ER QE R RE E + Q ++ E
Sbjct: 3208 DKQQQQLDLERELLELEK-IKQQRFAEELEWER--QEIQRFREQEKIMVQ-KKLEELQSM 3263
Query: 1282 RQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKRE 1332
+Q QQ +E+Q Q + +A Q Q Q L QQ E + R+
Sbjct: 3264 KQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKIRQ 3314
Score = 34.7 bits (78), Expect = 0.64
Identities = 35/137 (25%), Positives = 49/137 (35%), Gaps = 8/137 (5%)
Query: 913 LEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQ 972
+ D E + T ++ Q +++ + P T + Q+Q L PP P Q Q
Sbjct: 3834 MSDSEVSSTRPTRIESQHGIER-PRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSS 3892
Query: 973 QPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQ 1032
P P P QQ H H Q + T QP P Q P PQ
Sbjct: 3893 --PALPTQAPTSYTQQSHFEQQTLYHQQVSPYQT---QPTFQAVATMSFTPQVQPTPTPQ 3947
Query: 1033 PA--KPQQVIQHHHSPR 1047
P+ P Q++ PR
Sbjct: 3948 PSYQLPSQMMVIQQKPR 3964
Score = 33.9 bits (76), Expect = 1.1
Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 11/88 (12%)
Query: 1248 AEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAA 1307
+ K+ E +Q + R R L + EE R+E++ + QE+Q++ +QQ
Sbjct: 1746 SHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQ------- 1798
Query: 1308 ATPQAQSSQPQSMLDQQRELARKREQER 1335
Q +SS +S D+ EL +R +ER
Sbjct: 1799 ---QRKSSSKKSKKDKD-ELRAQRRRER 1822
Score = 32.7 bits (73), Expect = 2.4
Identities = 24/125 (19%), Positives = 59/125 (47%), Gaps = 10/125 (8%)
Query: 1211 TTPSSTAKSSSDSFEQFRRAAREKEEREKA--------LKAQAEHAEKEKERLRQERMRS 1262
T+P+S + DS E +++ KA L + +E+E+ R +E ++
Sbjct: 1729 TSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKE 1788
Query: 1263 REDEDALEQARR--AHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSM 1320
+E + +EQ +R + +++++ +++ + QR+ ++ + + A+P + Q M
Sbjct: 1789 QEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEM 1848
Query: 1321 LDQQR 1325
+ R
Sbjct: 1849 EELHR 1853
Score = 32.3 bits (72), Expect = 3.2
Identities = 37/167 (22%), Positives = 58/167 (34%), Gaps = 27/167 (16%)
Query: 653 EIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSS 712
EI +T T+R T +R + + E + I+ K S ++ ++S +
Sbjct: 3523 EISVQTEPVGTIR------TPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQ 3576
Query: 713 DSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQP-----PPPPQQP--- 764
+ PK KK+ P H +Q AP+P P+ P P P P
Sbjct: 3577 SPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSP-PKSPKVLYSPISPLSPGKA 3635
Query: 765 ------------PPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPP 799
P PQ+ P PP+ P+ A +S P
Sbjct: 3636 LESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDP 3682
Score = 31.6 bits (70), Expect = 5.4
Identities = 22/97 (22%), Positives = 46/97 (47%), Gaps = 6/97 (6%)
Query: 1244 QAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQ------ 1297
Q + + E+E L E+++ + + LE R+ + R +++ Q++ E+ Q
Sbjct: 3210 QQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQKKLEELQSMKQHLLF 3269
Query: 1298 QQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQE 1334
QQ+ A Q +Q Q L+Q ++L ++ Q+
Sbjct: 3270 QQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQ 3306
Score = 31.2 bits (69), Expect = 7.1
Identities = 23/104 (22%), Positives = 50/104 (48%), Gaps = 2/104 (1%)
Query: 1221 SDSFEQFRRAAREKEEREKAL-KAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEA 1279
++ E R+ + E+EK + + + E + K+ L ++ R+ + + Q A ++
Sbjct: 3232 AEELEWERQEIQRFREQEKIMVQKKLEELQSMKQHLLFQQEEERQAQFMMRQETLAQQQL 3291
Query: 1280 RRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQ 1323
+ Q QQ QQ Q QQ ++Q+ + + ++ PQ+ +Q
Sbjct: 3292 QLEQIQQLQQ-QLHQQLEEQKIRQIYQYNYDPSGTASPQTTTEQ 3334
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 119 bits (299), Expect = 2e-26
Identities = 201/920 (21%), Positives = 330/920 (35%), Gaps = 131/920 (14%)
Query: 476 PTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNK 535
P + A ++ +S + S S ++ E +L+E + + Q+AA+ Q
Sbjct: 13 PEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERR------QIAAVMSRAQGL 66
Query: 536 PKKKEKDKKEKKKEKHKRKE-EVEENKKSKAKEPPPKKTKKNNSSNSNVSK--KEPAPMK 592
PK + H+++E + K + P P + + S S + + +
Sbjct: 67 PKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLP 126
Query: 593 SKPPPTYESEEEDKCKPMSYEEKRQLS----LDINKLPGEKLGRVVH------IIQSREP 642
+ P T +E + E K + ++N L + VV+ +I E
Sbjct: 127 GRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNAL--SAVSSVVNKFNPFDLISDSEA 184
Query: 643 SLKNSNPDEIEIDFETLKPSTLRE--LERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSS 700
S + + + + E KP + + L++ + K++ P D + K SS
Sbjct: 185 SQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGR---DPLQQDGTPKSISS 241
Query: 701 SESE-------SSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPV 753
+ E + + ++ +T+ A K + R Q K + + P
Sbjct: 242 QQPEKIKSQPPGTGKPIQGPTQTPQTDHA-KLPLQRDASRPQTKQADIVRGESVKPSLPS 300
Query: 754 PQQPPPPPQQPPPPPPPQQQ----QQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLE 809
P + PP QQP P PP QQ + P P PP+ P + P T P ++
Sbjct: 301 PSK--PPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP----GTVKPPVQ 354
Query: 810 PQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQ 869
P PG+ P QP+ P PP E + A+ PP + QQ
Sbjct: 355 P--PGTTKPP----AQPL----GPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQ 404
Query: 870 --PSRPSNRAAALP-PKPARP----PAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPP 922
P++P + P P +P PA +P T+TP+ P P Q P
Sbjct: 405 PGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQ-------QAGPG 457
Query: 923 LTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQP 982
TS QQ +PP+ L K PPP P P P QQ +PP P
Sbjct: 458 KTS------AQQTGPTKPPSQLPGPAK----PPPQQPGPAKPPPQQPGSAKPPSQQPGST 507
Query: 983 QPPPQQQHQPPPRPVHLQPMQFSTHIQQP--PPPQGQQP-PHPPPGQQPPPP-------Q 1032
+PPPQQ P +P QP QQP P QQP P P QQ P +
Sbjct: 508 KPPPQQ--PGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK 565
Query: 1033 PAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSP-------- 1084
P +P V P + P + L + L++H P+ + F + T
Sbjct: 566 PLQPPTVSPSAKQP-PSQGLPKTICPLCNT-TELLLHVPEKANFNTCTECQTTVCSLCGF 623
Query: 1085 -PQQNVQPKKQEL-------------RAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLR 1130
P ++ K+ L A PQP + S + +S P
Sbjct: 624 NPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTS 683
Query: 1131 PEPPKHPESIKAPVHLPQRPE---MKPVDVGRPVIR---PPEQNAPPPGAPDKDKQ--KQ 1182
P+ P+ + P++P +P G P + PPE ++ AP K+ +
Sbjct: 684 PKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSE 743
Query: 1183 EPKTPVAPKKDLKIKNMGSWASLVQK-----HPTTPSSTAKSSSDSFEQFRRAAREKEER 1237
+ K PVA K + K + LV P PSS +S ++ + K +
Sbjct: 744 QDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEE----KTTPPLKTDS 799
Query: 1238 EKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQ 1297
K ++ EK + R D + + E ++Q Q+++E ++ Q
Sbjct: 800 AKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQ 859
Query: 1298 QQQAAAVAAAATPQAQSSQP 1317
+ + A P+ + P
Sbjct: 860 TKMSPKPDAKPMPKGSPTPP 879
Score = 95.5 bits (236), Expect = 3e-19
Identities = 249/1201 (20%), Positives = 398/1201 (33%), Gaps = 180/1201 (14%)
Query: 177 KGRGRGR---KETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHP-FPAVTPDL 232
K +G GR ++ GT K S P + S PP T P P T H P
Sbjct: 221 KQQGPGRDPLQQDGTPKSISSQQPEKIK-SQPPGTGKPIQGPTQTPQTDHAKLPLQRDAS 279
Query: 233 IVQTPVMTVV------PPQPLQTPPPVP-PQPQPPPAPAPQPVQSHPPIIAATPQPVKTK 285
QT +V P P + PP+ P P PPA P +S P QP
Sbjct: 280 RPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLT 339
Query: 286 KGVKRKADTTTPTTIDP-IHEPPSL---PPEPKTTKLGQRRESSRPVKPPKKDVPDS--- 338
K + ++ T P P +PP+ P +P + G + SS P P
Sbjct: 340 KPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGK 399
Query: 339 --QQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKH 396
Q P P K ++Q+ + ++ + A P PV G
Sbjct: 400 TPAQQPGPAKPP--TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPG---------- 447
Query: 397 PMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAK 456
I ++ AQ+ G PP A Q ++
Sbjct: 448 -----KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502
Query: 457 MPDE----PEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLA 512
P P++P A SP P TK PPS S+ S+ S S ++ + ++
Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTK---PPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS 559
Query: 513 EL--QEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPP 570
+ + L+ +A P Q PK + H P
Sbjct: 560 QTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLH-----------------VP 602
Query: 571 KKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKL 630
+K N + + P P +E C ++ + KR L D+ +P
Sbjct: 603 EKANFNTCTECQTTVCSLCGF--NPNPHLTEVKEWLC--LNCQMKRALGGDLAPVPSSPQ 658
Query: 631 GRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIA 690
++ + ++ S+P + P ++ ++ K+ P K +
Sbjct: 659 PKLKTAPVTTTSAVSKSSPQP-----QQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLH 713
Query: 691 GSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAP 750
GS K E++S S+ P K+ EQ K
Sbjct: 714 GSPSAKAKQPPEADSLSK--------------PAPPKEPSVPSEQDK------------- 746
Query: 751 APVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEP 810
APV P P+ P P PS Q+ K++PP + T +
Sbjct: 747 APVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPP--LKT-----DS 799
Query: 811 QLPGSVFDPIGHFTQPI--LHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQ 868
P F P G P +P+P + P S+ + V P Q
Sbjct: 800 AKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQ--VDP-------VQ 850
Query: 869 QPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQM 928
+ P + PKP P P + TP P+P Q + ++ P P S +
Sbjct: 851 KKEEPKKAQTKMSPKPDAKP--MPKGSPTPPGPRPTAG---QTVPTPQQSPKPQEQSRRF 905
Query: 929 QLYLQQL---QKVQPPTPLLP--------SVKVQSQPPPPLPPPPHPSVQQQ------LQ 971
L L + K QP TP + SQ + P Q ++
Sbjct: 906 SLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMK 965
Query: 972 QQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTH--IQQPPPPQGQQPPHPPPGQQPP 1029
Q P P PP Q PP+ Q PP P P++ T + P+ +Q P +
Sbjct: 966 QAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEK 1025
Query: 1030 PPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNV 1089
P P K + S L ++P P P ++ + PP N
Sbjct: 1026 KPPPIKDSK------SLTAEPQKAVLPTKLEKSPKPEST-CPLCKTELNIGSKDPPNFNT 1078
Query: 1090 QPK-KQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSL---RPEPPKHPESIKAPVH 1145
+ K ++ P P + +E + S L R PP
Sbjct: 1079 CTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPP----------- 1127
Query: 1146 LPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASL 1205
P P+ P+ V P ++ A PP KQ+QE KT K+K S
Sbjct: 1128 APSGPKASPMPV--PTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLS---- 1181
Query: 1206 VQKHPTTPSSTAKSSSDSFEQFRRAAREKE----EREKALKAQAEHAEKEKERLRQERMR 1261
++K P ++ K E+ + +A +++ E +K + + + +EK+ L +E+
Sbjct: 1182 MEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKP 1241
Query: 1262 SREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSML 1321
+ ED+ L +A+ + E EQ+ + Q Q +++ A T Q + QPQ+ +
Sbjct: 1242 TPEDKKLLPEAKTSAPE-----EQKHDLLKSQVQIAEEKLEGRVAPKTVQ-EGKQPQTKM 1295
Query: 1322 D 1322
+
Sbjct: 1296 E 1296
Score = 88.2 bits (217), Expect = 5e-17
Identities = 250/1307 (19%), Positives = 451/1307 (34%), Gaps = 226/1307 (17%)
Query: 184 KETGTAKPGVSTVPNTTQASTPP-----QTQTPQPNPPPVQATPHPFP-AVTPDLIVQTP 237
++TG+ KP S P + PP Q P P PP Q P P A P L Q+P
Sbjct: 374 QQTGSEKPS-SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGL--QSP 430
Query: 238 VMTVVPPQ-PLQTPPP--VPPQ-------------PQPPPAPAPQPVQSHPPIIAATPQP 281
P + P+Q P P +P Q P PP+ P P + P QP
Sbjct: 431 AKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQ------QP 484
Query: 282 VKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQH 341
K ++ P+ +PP P P Q + P + P P +QQ
Sbjct: 485 GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQP 544
Query: 342 PAPEKSSKVSEQLKCCSGILKEMFAKKHAAYA-WPFYKPVDVEALGLHDYCDIIKHPMDM 400
+ S++ S + +G K + + A P + + L + +++ H +
Sbjct: 545 SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEK 604
Query: 401 STIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDH-----EVVAMARKLQDVFEMRFA 455
+ + E + + S C +NP H E + + +++ A
Sbjct: 605 ANFNTCTECQ------------TTVCSLC-GFNPNPHLTEVKEWLCLNCQMKRALGGDLA 651
Query: 456 KMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQ 515
+P P+ + A T V+ S + D+ D S+ ++ L
Sbjct: 652 PVPSSPQPKL----KTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLV 707
Query: 516 EQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKK 575
+Q A QP + K KE + K V ++K + K P
Sbjct: 708 KQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLV 767
Query: 576 NNSS------------NSNVSKKEPAPMK---SKP----PPTYE--SEEEDKCKPMSYEE 614
++SS S +K P+K +KP PPT E S + K P +
Sbjct: 768 SSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASD 827
Query: 615 KRQLSLDINKLPGEKLGRVVHIIQSREP----SLKNSNPDEIEIDFETLKPSTLRELERY 670
+ +S + +V + + EP + + PD + + P R
Sbjct: 828 SKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887
Query: 671 VTSCLRKKRKP--QAEKVDVIAGS-----------------SKMKGFSSS-ESESSSESS 710
++ KP Q+ + + GS K+ GF +S S++S+ S
Sbjct: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947
Query: 711 SSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAP--------------APVPQQ 756
++ ++ P + K P Q + QAP AP ++
Sbjct: 948 TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK 1007
Query: 757 PPPPPQQPPPPPPPQQQQQPPPPPPPPSM---PQQAAPAMKSSPPPFIATQVPVLEPQLP 813
P +Q P + +++PPP S+ PQ+A K P + P+ + +L
Sbjct: 1008 LEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELN 1067
Query: 814 GSVFDPIGHFT-----QPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQ 868
DP T + +L PHL + E Q A+ +P
Sbjct: 1068 IGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPP 1127
Query: 869 QPSRPSNRAAALPPK-PARPPAVSPALTQTPLLPQPPMAQPPQVLLE------DEEPPAP 921
PS P +P + ++ AV P + Q + +V+LE E P
Sbjct: 1128 APSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPP 1187
Query: 922 PLTSMQMQ----------LYLQQLQKVQPPTPLLP-SVKVQSQPPPPLPPPPHPSVQQQL 970
+T+ Q Q LQ+ + + L+P K++S+ PL L
Sbjct: 1188 MVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPL-----------L 1236
Query: 971 QQQPPPP------PPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPP 1024
+++ P P P + P +Q+H V + + + +G+QP
Sbjct: 1237 EEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKME 1296
Query: 1025 G---------------------QQPPPPQPAKPQQV------------------IQHHHS 1045
G +QP PP AKP QV Q S
Sbjct: 1297 GLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKS 1356
Query: 1046 PRHHKSDPYS----TGHLREAPSPLMIHSPQM---SQFQSLTHQSPPQQNVQPKKQELRA 1098
P+ YS + L E PS + + + S + +S P K E
Sbjct: 1357 PQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTV 1416
Query: 1099 ASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVG 1158
S+++ Q + E+ +++P S PE PK E ++ E + +
Sbjct: 1417 LSILEAQASTLADEKSEK----KTQPHEVS--PEQPKDQEKTQS------LSETLEITIS 1464
Query: 1159 RPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKN--MGSWASLVQKHPTTPSST 1216
I+ ++ KD K++ + + KD K K+ + + + + + S+
Sbjct: 1465 EEEIKESQEER-------KDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESS 1517
Query: 1217 AKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAH 1276
+S ++ RR + ++ + ++ + +E++ +R++ + DEDA +
Sbjct: 1518 ESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDA---SGSED 1574
Query: 1277 EEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQ 1323
+E R Q ++ E Q++++ + A + + + + +D+
Sbjct: 1575 DEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDE 1621
Score = 87.8 bits (216), Expect = 6e-17
Identities = 193/915 (21%), Positives = 302/915 (33%), Gaps = 191/915 (20%)
Query: 431 KYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPPPTKVVAP---PSSSD 487
K+NP D +++ + Q+ + + E +P + P P K + P
Sbjct: 172 KFNPFD--LISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDP 229
Query: 488 SSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNK----PKKKEKDK 543
D + S SS Q+ +++ Q + + +Q Q P +++ +
Sbjct: 230 LQQDGTPKSISS---------QQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASR 280
Query: 544 KEKKKEKHKRKEEVEENKKSKAKEPPPKKTK-KNNSSNSNVSKKEPAPMK--------SK 594
+ K+ R E V+ + S +K P + T K + K +P P K +K
Sbjct: 281 PQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTK 340
Query: 595 PPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEI 654
P + +P + L K P ++ G S +PS + P +
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTG-------SEKPSSEQPGPKALAQ 393
Query: 655 D-----FETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSK----MKGFSSSESES 705
+P + + V + ++P + G +K G ++
Sbjct: 394 PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQ 453
Query: 706 SSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQA--PAPVPQQPPPPPQQ 763
+ +S + T+ + P +Q QQ A P+ P PPPQQ
Sbjct: 454 AGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQ 513
Query: 764 PPPPPPPQQQ--------QQPPPPPPPPSMPQQAAPAMKSSPPPFIAT------QVPVLE 809
P P P QQ QQP P P A P+ + S P T Q P +
Sbjct: 514 PGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS 573
Query: 810 PQ--------LPGSVFDPIGHFTQPILHLPQP-------------------ELPPHLPQ- 841
P LP ++ P+ + T+ +LH+P+ PHL +
Sbjct: 574 PSAKQPPSQGLPKTIC-PLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEV 632
Query: 842 -------------------PPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALP- 881
P S P L V + A+ + PQ P + S + A P
Sbjct: 633 KEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQ-PQQTSPKKDAAPK 691
Query: 882 ------PKPARPPAVSPALTQTPLLPQPPMA---QPPQV--LLEDEEPPAPPLTSMQMQL 930
P+P +PP L + P L P A QPP+ L + P P + S Q +
Sbjct: 692 QDLSKAPEPKKPPP----LVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKA 747
Query: 931 YL-----QQLQKVQPPTPL-----------LPSVKVQSQPPPPLPPPPHPSVQQQLQQQP 974
+ +Q + V+P T L +PS KVQSQ PP + Q P
Sbjct: 748 PVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFP 807
Query: 975 PP------------PPP---------PQPQPPPQQQHQPPPRPVHLQPMQFSTHIQ---- 1009
P P P P P + Q Q P +P + T +
Sbjct: 808 PTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD 867
Query: 1010 -QPPPPQGQQPPHPPP--GQQPPPPQPA-KPQQVIQHHH--------SPRHHKSDPYSTG 1057
+P P PP P P GQ P PQ + KPQ+ + +P+ + P T
Sbjct: 868 AKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETV 927
Query: 1058 HLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHS 1117
+ I S Q S S Q P P +A + QP
Sbjct: 928 TGKLFGFGASIFS-QASNLISTAGQPGPHSQSGPGAPMKQAPAPSQP------------- 973
Query: 1118 PIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDK 1177
P + P S P P +K P +++P P ++ E PP D
Sbjct: 974 PTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDS 1033
Query: 1178 DKQKQEPKTPVAPKK 1192
EP+ V P K
Sbjct: 1034 KSLTAEPQKAVLPTK 1048
Score = 67.0 bits (162), Expect = 1e-10
Identities = 59/197 (29%), Positives = 78/197 (39%), Gaps = 37/197 (18%)
Query: 753 VPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQL 812
+ QPPPPP PPPPPP PPPPPPPP +P +P P + PV
Sbjct: 2401 ISAQPPPPPPPPPPPPP------PPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTAT- 2453
Query: 813 PGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSR 872
+FD + + L LP + + +PP + P+ S
Sbjct: 2454 --PLFDAVTTLETTAV-LRSNGLP--------------VTRICTTAPPPVP---PKPSSI 2493
Query: 873 PSNRAAALPPKPARPP-AVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLT-SMQMQL 930
PS P+P++PP A P + Q P Q P P +P LT SM + L
Sbjct: 2494 PSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHP-------KPTGLSLTSSMTLNL 2546
Query: 931 YLQQLQKVQPPT-PLLP 946
K+ PT PL P
Sbjct: 2547 VTSADYKLPSPTSPLSP 2563
Score = 60.5 bits (145), Expect = 1e-08
Identities = 60/241 (24%), Positives = 87/241 (36%), Gaps = 46/241 (19%)
Query: 748 QAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQ----AAPAMKSS------- 796
Q P P P PPPPP PPPPPPP PP P P +P++ A+P ++
Sbjct: 2404 QPPPPPPPPPPPPPPPPPPPPPP---LPPPTSPKPTILPKKKLTVASPVTTATPLFDAVT 2460
Query: 797 -------------PPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPP 843
P I T P P P S+ P G H P+P PP P+P
Sbjct: 2461 TLETTAVLRSNGLPVTRICTTAPPPVPPKPSSI--PSG---LVFTHRPEPSKPPIAPKPV 2515
Query: 844 EHSTP----------PHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPA 893
P P ++ S L+ PS + P P S +
Sbjct: 2516 IPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKS 2575
Query: 894 LTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQ 953
LT+T ++ + P + + + +TS + + L V+P ++P V
Sbjct: 2576 LTETYVV----ITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEI 2631
Query: 954 P 954
P
Sbjct: 2632 P 2632
Score = 60.1 bits (144), Expect = 1e-08
Identities = 52/174 (29%), Positives = 64/174 (36%), Gaps = 33/174 (18%)
Query: 206 PQTQTPQPNPP--PVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAP 263
P +Q P +P + A P PF + I P PP P PPP PP P PPP P
Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQP-----PPPPPPPPPPPPPPPPPPPPP 2426
Query: 264 APQPVQSHP------------PIIAATP--QPVKTKKGVKRKADTTTPTTIDPIHEPPSL 309
P P P P+ ATP V T + P T PP +
Sbjct: 2427 LPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPV 2486
Query: 310 PPEPKTTKLG----QRRESSRPVKPPKKDVPD--------SQQHPAPEKSSKVS 351
PP+P + G R E S+P PK +P + HP P S S
Sbjct: 2487 PPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTS 2540
Score = 59.7 bits (143), Expect = 2e-08
Identities = 58/217 (26%), Positives = 75/217 (34%), Gaps = 58/217 (26%)
Query: 939 QPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVH 998
+ P LPS P P P S + QPPPPPPP P PPP PPP
Sbjct: 2370 EKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPP-----PPP---- 2420
Query: 999 LQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGH 1058
PPPP PP PPP P P K V
Sbjct: 2421 ------------PPPP----PPLPPPTSPKPTILPKKKLTV------------------- 2445
Query: 1059 LREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSP 1118
SP+ +P +L + + N P + A P V K I S
Sbjct: 2446 ----ASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTA-----PPPVPPKPSSIPSG 2496
Query: 1119 II---RSEPFSPSLRPEP--PKHPESIKAPVHLPQRP 1150
++ R EP P + P+P P+ P + + P + +P
Sbjct: 2497 LVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKP 2533
Score = 55.8 bits (133), Expect = 3e-07
Identities = 78/320 (24%), Positives = 109/320 (34%), Gaps = 78/320 (24%)
Query: 883 KPARP-PAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPP 941
KPA P+ SP+++ P P+P + PP PP PP
Sbjct: 2371 KPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP-----------------PP 2413
Query: 942 TPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQP---PPQQQHQPPPRPVH 998
P PPPP PPP PP PPP P+P P ++ P
Sbjct: 2414 PP---------PPPPPPPPP------------PPLPPPTSPKPTILPKKKLTVASPVTTA 2452
Query: 999 LQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQV---IQHHHSPRHHKSDPYS 1055
T ++ + P PPP P KP + + H P K
Sbjct: 2453 TPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPP--- 2509
Query: 1056 TGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKI 1115
AP P++ PQ+ T Q P + +P L ++ + LV + K+
Sbjct: 2510 -----IAPKPVI---PQL----PTTTQKPTDIHPKPTGLSLTSSMTLN---LVTSADYKL 2554
Query: 1116 HSPIIRSEPFSPSLRPEPPKHPESIK---APVHLPQRPEMKPVDVGRPVIRPPEQ--NAP 1170
SP + P SP P+ +S+ + LP P G P Q +
Sbjct: 2555 PSP---TSPLSPHSNKSSPRFSKSLTETYVVITLPSEP-------GTPTDSSASQAITSW 2604
Query: 1171 PPGAPDKDKQKQEPKTPVAP 1190
P G+P KD EP V P
Sbjct: 2605 PLGSPSKDLVSVEPVFSVVP 2624
Score = 53.9 bits (128), Expect = 1e-06
Identities = 126/625 (20%), Positives = 224/625 (35%), Gaps = 110/625 (17%)
Query: 141 KPGDDIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTT 200
KP D+V + A K ++P+ + + QA+ + +T +AKP S P
Sbjct: 761 KPTTDLVSSSSATTK------PDIPSSKVQS---QAEEKTTPPLKTDSAKPSQSFPPTGE 811
Query: 201 QASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQT-PVMTVVPPQPLQTPPPVPPQPQP 259
+ S P+P + HP P+ Q PV P+ QT P +P
Sbjct: 812 KVSPFDSKAIPRPASDS-KIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKP 870
Query: 260 PPAPAPQPVQSHPPIIAATPQPVKTKKGVK--RKADTTTPTTIDPIHEPPSLPPEPKTTK 317
P +P P P P P ++ K + R+ + D P+ P E T K
Sbjct: 871 MPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGK 930
Query: 318 L------------------GQ------------RRESSRPVKPPKKDVP---DSQQHPAP 344
L GQ +++ P +PP P Q PAP
Sbjct: 931 LFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAP 990
Query: 345 EKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEAL--GLHDYCDIIKHPMDMST 402
KS V ++ K + E A++ P K + E + D + P +
Sbjct: 991 AKSIPVKKETKAPAAEKLEPKAEQA-----PTVKRTETEKKPPPIKDSKSLTAEP-QKAV 1044
Query: 403 IKSKLEARE----------------YRDAQEFG--ADVRLMFSNCYKYNPPDHEVV---- 440
+ +KLE +D F + + N +NP H
Sbjct: 1045 LPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEW 1104
Query: 441 ---------AMARKLQDVFEMRFAKM-PDEPEEPVVAVSS---PAVPPPTKVVAPPSSSD 487
A++ +L D+ +M A P PV SS AVPP K+V
Sbjct: 1105 LCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEV 1164
Query: 488 SSSDSSSDSDSSTDDSEEERAQRLA---ELQEQLKAVHEQLAALSQPQQNKPKKKEKDKK 544
+ + + E+ + + QE+ K ++ +AL Q ++ P++K+ +
Sbjct: 1165 KTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASAL-QEKKPLPEEKKLIPE 1223
Query: 545 EKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEE 604
E+K ++K +EE K+P P+ K + ++ +++ + E + E
Sbjct: 1224 EEKIRSEEKKPLLEE------KKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLE 1277
Query: 605 DKCKPMSYEEKRQLSLDINKLPG-------EKLGRVVHIIQSREPSLKNSNPDEIEIDFE 657
+ P + +E +Q + LP ++ + I+ + + PD++E
Sbjct: 1278 GRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPG-- 1335
Query: 658 TLKPSTLRELERYVTSCLRKKRKPQ 682
K T +E ++ TS ++ + PQ
Sbjct: 1336 --KEKTEKEDDKSDTSSSQQPKSPQ 1358
Score = 51.2 bits (121), Expect = 7e-06
Identities = 47/174 (27%), Positives = 71/174 (40%), Gaps = 23/174 (13%)
Query: 174 VQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQ--PNPPPVQATPHPFPAVTPD 231
+Q+ + G +T +PG +P Q + P +T Q P PP Q P PA P
Sbjct: 427 LQSPAKAPGPTKTPVQQPGPGKIP--AQQAGPGKTSAQQTGPTKPPSQL---PGPAKPP- 480
Query: 232 LIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRK 291
P QP PP P QP P+ QP + PP P ++ K
Sbjct: 481 -----------PQQPGPAKPP-PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK 528
Query: 292 ADTTTPTTIDPIHEPPS--LPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPA 343
+ P + P + PS P ++TK + S +P++PP P ++Q P+
Sbjct: 529 PPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS-PSAKQPPS 581
Score = 50.1 bits (118), Expect = 1e-05
Identities = 48/179 (26%), Positives = 65/179 (36%), Gaps = 14/179 (7%)
Query: 176 AKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATP-HPF-PAVTP--D 231
A+ G + + G AKP T + P T P PP P P PA P
Sbjct: 316 AQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQ 375
Query: 232 LIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRK 291
+ P P+ L PP V P P PA P Q TP+P+ + G++
Sbjct: 376 TGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQ-----VGTPKPLAQQPGLQSP 430
Query: 292 ADTTTPTTIDPIHEP-PSLPPEPKTTKLGQRRESSRPVKPPKK---DVPDSQQHPAPEK 346
A PT P+ +P P P + + + P KPP + Q P P K
Sbjct: 431 AKAPGPTK-TPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAK 488
Score = 47.4 bits (111), Expect = 1e-04
Identities = 42/147 (28%), Positives = 55/147 (37%), Gaps = 17/147 (11%)
Query: 175 QAKGRGR-GRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLI 233
Q G G+ ++TG KP P+ P Q P P PP Q P A P
Sbjct: 452 QQAGPGKTSAQQTGPTKP-----PSQLPGPAKPPPQQPGPAKPPPQ---QPGSAKPPS-- 501
Query: 234 VQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKAD 293
Q P T PPQ P P QP P+ QP + P +P ++ K +
Sbjct: 502 -QQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ 560
Query: 294 TTT-----PTTIDPIHEPPSLPPEPKT 315
T + P T+ P + P PKT
Sbjct: 561 TGSGKPLQPPTVSPSAKQPPSQGLPKT 587
Score = 46.6 bits (109), Expect = 2e-04
Identities = 120/597 (20%), Positives = 213/597 (35%), Gaps = 93/597 (15%)
Query: 165 PTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHP 224
PT E + ++ +AK ++ K V + P+T P Q
Sbjct: 1241 PTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQP---QTKMEG 1297
Query: 225 FPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQ--------SHPPIIA 276
P+ TP + P + +T + QPQPP P V+
Sbjct: 1298 LPSGTPQSL---------PKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDT 1348
Query: 277 ATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVP 336
++ Q K+ +G+ ++ + P +P + K G +++S ++ P
Sbjct: 1349 SSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSF-----SQESSP 1403
Query: 337 DSQQHPAPEKSSKVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKH 396
S A +S+ +S S + E KK + +P D E K
Sbjct: 1404 SSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQE-----------KT 1452
Query: 397 PMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAK 456
T++ + E +++QE D S + DH+ K + V ++ +
Sbjct: 1453 QSLSETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHK-----EKSEFVDDITTRR 1507
Query: 457 MP-DEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSE-------EERA 508
P D EE + +SP P K SS S DS S ++ + E A
Sbjct: 1508 EPYDSVEESSESENSPV--PQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSA 1565
Query: 509 QRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEP 568
A E + + QL +S +++ K++ K K + KH+R +KS
Sbjct: 1566 DEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRL-----TRKSSTSID 1620
Query: 569 PPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGE 628
+ + + + E +K + + ESEE +R ++++N +
Sbjct: 1621 EDAGRRHSWHDEDDEAFDESPELKYRETKSQESEE--LVVTGGGGLRRFKTIELNSTIAD 1678
Query: 629 KLGRVVHIIQSREPSLKNSN---PDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEK 685
K S E S K ++ +E E++ E+L S + + + E
Sbjct: 1679 K--------YSAESSQKKTSLYFDEEPELEMESLTDS--------------PEDRSRGE- 1715
Query: 686 VDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHH 742
GSS + S + S + SS D EDS++ S KKG +++K H H
Sbjct: 1716 -----GSSSLHASSFTPGTSPTSVSSLD-EDSDSS---PSHKKGESKQQRKARHRPH 1763
Score = 44.7 bits (104), Expect = 6e-04
Identities = 45/154 (29%), Positives = 60/154 (38%), Gaps = 28/154 (18%)
Query: 874 SNRAAALPPKPARPPAVSPAL---TQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQL 930
S ++LP KP RP S +L Q P P PP PP PP PP TS + +
Sbjct: 2380 SPSVSSLPAKP-RPFFRSSSLDISAQPPPPPPPPPPPPPPP-PPPPPPPLPPPTSPKPTI 2437
Query: 931 YLQQLQKVQPP----TPL-----------------LPSVKVQSQPPPPLPPPPH--PSVQ 967
++ V P TPL LP ++ + PPP+PP P PS
Sbjct: 2438 LPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGL 2497
Query: 968 QQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQP 1001
+ P PP P+P Q +P + P
Sbjct: 2498 VFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHP 2531
Score = 44.3 bits (103), Expect = 8e-04
Identities = 66/298 (22%), Positives = 117/298 (39%), Gaps = 23/298 (7%)
Query: 462 EEPVVAVSSPAVPPPTKVVAPPSSSDSSSD----SSSDSDSSTD-DSEEERAQRLAELQE 516
EEP + + S P + SSS +S +S S SS D DS+ + + E ++
Sbjct: 1695 EEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQ 1754
Query: 517 QLKAVHEQLAALSQPQQNKPKKKE---------KDKKEKKKEKHKRKEEVEENKKSKAKE 567
Q KA H L ++ +++E + +K+++ E+ +RK +++KK K +
Sbjct: 1755 QRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDEL 1814
Query: 568 PPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPG 627
++ ++ + SN+S E A + E EE + Y + + ++
Sbjct: 1815 RAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEGFEISP 1874
Query: 628 EKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRK----PQA 683
EK+ V + + S DE I + L+ E + K K P A
Sbjct: 1875 EKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGSQKALKSAEEMYEEMMHKTHKYKAFPAA 1934
Query: 684 EKVDVIAGSSKMKGFSSSES---ESSSESSSSDSEDSE--TEMAPKSKKKGHPGREQK 736
+ D + + G E ES E + + S D T ++ GREQK
Sbjct: 1935 NERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEENGFMQQKGREQK 1992
Score = 43.5 bits (101), Expect = 0.001
Identities = 61/288 (21%), Positives = 110/288 (38%), Gaps = 42/288 (14%)
Query: 1077 QSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKH 1136
Q L+ SPP+ +P E+ +S ++ V + SP + P SP P K
Sbjct: 3579 QYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPL---SPGKA 3635
Query: 1137 PESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQ----EPKTPVAPKK 1192
ES P P P D+ + P+ PP +P K Q +PK P++P
Sbjct: 3636 LESAFVPYEKPL-----PDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPK-PLSPTA 3689
Query: 1193 DLKIK------------------NMGSWASLVQKHPTTPSSTAKSSSDS-FEQFRRAARE 1233
D + + G+ + + P P + + S F +R
Sbjct: 3690 DESSRAPFQYTEGYTTKGSQTMTSSGAQKKVKRTLPNPPPEEISTGTQSTFSTMGTVSRR 3749
Query: 1234 K------EEREKALK---AQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEA-RRRQ 1283
+ R K L+ + + E+E +LR+++ E+E ++ R E RR+
Sbjct: 3750 RICRTNTMARAKILQDIDRELDLVERESAKLRKKQAELDEEEKEIDAKLRYLEMGINRRK 3809
Query: 1284 EQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKR 1331
E ++R+++++ Q A + SS + ++ Q + R R
Sbjct: 3810 EALLKEREKRERAYLQGVAEDRDYMSDSEVSSTRPTRIESQHGIERPR 3857
Score = 37.0 bits (84), Expect = 0.13
Identities = 37/124 (29%), Positives = 51/124 (41%), Gaps = 27/124 (21%)
Query: 237 PVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTT 296
P + PP Q P P+P Q P P Q TP+ + +++ K K+
Sbjct: 203 PEGIIKPPLQQQPPKPIPKQQGPGRDPLQQD---------GTPKSISSQQPEKIKSQ--P 251
Query: 297 PTTIDPIHEPPSLPPEPKTTKLGQRRESSRP------------VKP--PKKDVPDSQQHP 342
P T PI + P+ P+ KL +R++SRP VKP P P QQ P
Sbjct: 252 PGTGKPI-QGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQ-P 309
Query: 343 APEK 346
P K
Sbjct: 310 TPGK 313
Score = 35.0 bits (79), Expect = 0.49
Identities = 36/111 (32%), Positives = 48/111 (43%), Gaps = 4/111 (3%)
Query: 1222 DSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARR 1281
D +Q RE E EK +K Q E E ER QE R RE E + Q ++ E
Sbjct: 3208 DKQQQQLDLERELLELEK-IKQQRFAEELEWER--QEIQRFREQEKIMVQ-KKLEELQSM 3263
Query: 1282 RQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRELARKRE 1332
+Q QQ +E+Q Q + +A Q Q Q L QQ E + R+
Sbjct: 3264 KQHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKIRQ 3314
Score = 34.7 bits (78), Expect = 0.64
Identities = 35/137 (25%), Positives = 49/137 (35%), Gaps = 8/137 (5%)
Query: 913 LEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQ 972
+ D E + T ++ Q +++ + P T + Q+Q L PP P Q Q
Sbjct: 3834 MSDSEVSSTRPTRIESQHGIER-PRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSS 3892
Query: 973 QPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQ 1032
P P P QQ H H Q + T QP P Q P PQ
Sbjct: 3893 --PALPTQAPTSYTQQSHFEQQTLYHQQVSPYQT---QPTFQAVATMSFTPQVQPTPTPQ 3947
Query: 1033 PA--KPQQVIQHHHSPR 1047
P+ P Q++ PR
Sbjct: 3948 PSYQLPSQMMVIQQKPR 3964
Score = 33.9 bits (76), Expect = 1.1
Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 11/88 (12%)
Query: 1248 AEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAA 1307
+ K+ E +Q + R R L + EE R+E++ + QE+Q++ +QQ
Sbjct: 1746 SHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQ------- 1798
Query: 1308 ATPQAQSSQPQSMLDQQRELARKREQER 1335
Q +SS +S D+ EL +R +ER
Sbjct: 1799 ---QRKSSSKKSKKDKD-ELRAQRRRER 1822
Score = 32.7 bits (73), Expect = 2.4
Identities = 24/125 (19%), Positives = 59/125 (47%), Gaps = 10/125 (8%)
Query: 1211 TTPSSTAKSSSDSFEQFRRAAREKEEREKA--------LKAQAEHAEKEKERLRQERMRS 1262
T+P+S + DS E +++ KA L + +E+E+ R +E ++
Sbjct: 1729 TSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKE 1788
Query: 1263 REDEDALEQARR--AHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSM 1320
+E + +EQ +R + +++++ +++ + QR+ ++ + + A+P + Q M
Sbjct: 1789 QEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEM 1848
Query: 1321 LDQQR 1325
+ R
Sbjct: 1849 EELHR 1853
Score = 32.3 bits (72), Expect = 3.2
Identities = 37/167 (22%), Positives = 58/167 (34%), Gaps = 27/167 (16%)
Query: 653 EIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSS 712
EI +T T+R T +R + + E + I+ K S ++ ++S +
Sbjct: 3523 EISVQTEPVGTIR------TPSIRARVDAKVEIIKHISAPEKTYKGGSLGCQTEADSDTQ 3576
Query: 713 DSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQP-----PPPPQQP--- 764
+ PK KK+ P H +Q AP+P P+ P P P P
Sbjct: 3577 SPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSP-PKSPKVLYSPISPLSPGKA 3635
Query: 765 ------------PPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPP 799
P PQ+ P PP+ P+ A +S P
Sbjct: 3636 LESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDP 3682
Score = 31.6 bits (70), Expect = 5.4
Identities = 22/97 (22%), Positives = 46/97 (47%), Gaps = 6/97 (6%)
Query: 1244 QAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQ------ 1297
Q + + E+E L E+++ + + LE R+ + R +++ Q++ E+ Q
Sbjct: 3210 QQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQKKLEELQSMKQHLLF 3269
Query: 1298 QQQAAAVAAAATPQAQSSQPQSMLDQQRELARKREQE 1334
QQ+ A Q +Q Q L+Q ++L ++ Q+
Sbjct: 3270 QQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQ 3306
Score = 31.2 bits (69), Expect = 7.1
Identities = 23/104 (22%), Positives = 50/104 (48%), Gaps = 2/104 (1%)
Query: 1221 SDSFEQFRRAAREKEEREKAL-KAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEA 1279
++ E R+ + E+EK + + + E + K+ L ++ R+ + + Q A ++
Sbjct: 3232 AEELEWERQEIQRFREQEKIMVQKKLEELQSMKQHLLFQQEEERQAQFMMRQETLAQQQL 3291
Query: 1280 RRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQ 1323
+ Q QQ QQ Q QQ ++Q+ + + ++ PQ+ +Q
Sbjct: 3292 QLEQIQQLQQ-QLHQQLEEQKIRQIYQYNYDPSGTASPQTTTEQ 3334
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 118 bits (295), Expect = 4e-26
Identities = 166/796 (20%), Positives = 269/796 (33%), Gaps = 85/796 (10%)
Query: 453 RFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPS-SSDSSSDSSSDSDSSTDDSEEERAQRL 511
++ K + E V +P PP +K PPS +S + ++ S + + ++
Sbjct: 51 KYDKCCPDYESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIES 110
Query: 512 AELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHK---RKEEVEENKKSKAKEP 568
E+ E+ Q ++ S + K K K ++ +K +V++NKK++ K+
Sbjct: 111 EEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKK 170
Query: 569 PPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGE 628
P K + + S + + K P T ++ +S K + IN
Sbjct: 171 PTPKPPVVDEAGSGLDNGD---FKVTTPDTSTTQH----NKVSTSPKITTAKPINP---- 219
Query: 629 KLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDV 688
PSL ++ E K +T+ E T
Sbjct: 220 ------------RPSLPPNSDTSKETSLTVNKETTVETKETTTT---------------- 251
Query: 689 IAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQ 748
+K E +S++ + S + S ++AP SK P K +
Sbjct: 252 ----NKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP--TPKAETTTKGPALTT 305
Query: 749 APAPVPQQPPPPPQQPPPPPPPQQ-QQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPV 807
P P P P P P P + P P P ++AP P P +
Sbjct: 306 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 365
Query: 808 LEPQ--LPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNA 865
P+ P + +P T+ P+ E P P+ P +TP + A +P
Sbjct: 366 TTPKEPAPTTTKEPAPTTTKSAPTTPK-EPAPTTPKKPAPTTP---KEPAPTTPKEPTPT 421
Query: 866 LPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDE------EPP 919
P++P+ + A PK P A TP P P + P E + P
Sbjct: 422 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 481
Query: 920 APPLTSMQMQLYLQ---QLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQ----LQQ 972
AP T + K P TP PS +P P P P P+ ++ +
Sbjct: 482 APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 541
Query: 973 QPPPPPPPQPQPPPQQQHQP--PPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPP 1030
+P P P +P P ++ P P P P + + + P + P ++P P
Sbjct: 542 EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP 601
Query: 1031 PQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQ 1090
P + +P +P T AP+ +P + + T P
Sbjct: 602 TTPEELAPTTPEEPTPT-TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT- 659
Query: 1091 PKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRP 1150
PK+ P L K +P +P L P K P S P P
Sbjct: 660 PKETAPTTPKGTAPTTL------KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 713
Query: 1151 E-MKPVDVGRPVIRPPEQNAP--PPGAPDKDKQKQEPKTP--VAPKKDLKIKNMGSWASL 1205
+ P P P++ AP P G ++ P TP APK+ G ++
Sbjct: 714 KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTT 773
Query: 1206 VQK-HPTTPSSTAKSS 1220
K PTTP TA ++
Sbjct: 774 SDKPAPTTPKETAPTT 789
Score = 105 bits (262), Expect = 3e-22
Identities = 157/756 (20%), Positives = 253/756 (33%), Gaps = 90/756 (11%)
Query: 464 PVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHE 523
P + + P P P+ PP+S S S + + +T +++E +Q +
Sbjct: 209 PKITTAKPINPRPS---LPPNSDTSKETSLTVNKETTVETKETTTTN-----KQTSTDGK 260
Query: 524 QLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNV 583
+ ++ Q+ K KD K K + E K A P + T ++
Sbjct: 261 EKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAST 320
Query: 584 SKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPS 643
+ KEP P K PT E + ++ + K P +EP+
Sbjct: 321 TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT--------PKEPA 372
Query: 644 LKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSES 703
P+T +E T K P K A ++ K ++
Sbjct: 373 -----------------PTTTKEPAPTTT-----KSAPTTPKEP--APTTPKKPAPTTPK 408
Query: 704 ESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPV-PQQPPPPPQ 762
E + + + + E AP +K+ P K PAP P++P P
Sbjct: 409 EPAPTTPKEPTPTTPKEPAPTTKE---PAPTTPKE-----------PAPTAPKKPAPTTP 454
Query: 763 QPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGH 822
+ P P P++ P P+ P++ AP S P P P + +P
Sbjct: 455 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 514
Query: 823 FTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSP--PALHNALPQQPSRPSNRAAAL 880
T+ E P P+ P +TP + A +P PA P+ P A
Sbjct: 515 TTKEPAPTTPKEPAPTTPKKPAPTTP---KEPAPTTPKEPAPTTTKKPAPTTPKEPAPTT 571
Query: 881 PPK--PARPPAVSPALTQ--TPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQ 936
P + P P ++P + P P+ P P+ L P P + + +
Sbjct: 572 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA--PTTPEEPTPTTPEEPAPTTPK 629
Query: 937 KVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRP 996
P TP P+ +P P P P P+ ++ P P P P P
Sbjct: 630 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 689
Query: 997 VHLQPM----QFSTHIQQPPP--PQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHK 1050
L P ST +P P P+G P P ++P P P +P +P K
Sbjct: 690 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP---KEPAPTTPKEPAPTTPKGTAPTTLK 746
Query: 1051 SDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSP--PQQNVQPKKQELRAASVVQPQPLV 1108
+P T + AP L + + + +P P++ +E + +P P
Sbjct: 747 -EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT 805
Query: 1109 ----VVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRP 1164
++ +P EP + P+ PE P P+ E P + G P +
Sbjct: 806 PETPPPTTSEVSTPTTTKEPTTIHKSPD-ESTPELSAEPT--PKALENSPKEPGVPTTKT 862
Query: 1165 PEQNAPPPGAPDKDKQKQE-----PKTPVAPKKDLK 1195
P P KDK + P+T A K K
Sbjct: 863 PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTK 898
Score = 57.4 bits (137), Expect = 9e-08
Identities = 49/176 (27%), Positives = 61/176 (34%), Gaps = 21/176 (11%)
Query: 186 TGTAKPGVSTV---PNTTQASTPPQTQTPQPNPP--PVQATPHPFPAVTPDLIVQTPVMT 240
T T +P +T P T + P + P P P P TP TP + P T
Sbjct: 374 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP----KEPAPT 429
Query: 241 VVPPQPLQTPPPVP-----PQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTT 295
P P P P P P P PAP + P P P K+ +
Sbjct: 430 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 489
Query: 296 TPTTIDP----IHEPPSLP--PEPKTTKLGQRRESSRPV-KPPKKDVPDSQQHPAP 344
TT +P P+ P P P TTK P PKK P + + PAP
Sbjct: 490 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 545
Score = 55.5 bits (132), Expect = 4e-07
Identities = 49/170 (28%), Positives = 61/170 (35%), Gaps = 14/170 (8%)
Query: 186 TGTAKPGVSTV---PNTTQASTPPQTQTPQPNPP--PVQATPHPFPAVTPDLIVQTPVMT 240
T T +P +T P T + +P T+ P P P P TP TP T T
Sbjct: 491 TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT---T 547
Query: 241 VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI 300
P P T P P P+ P P+ P P K K TTP +
Sbjct: 548 PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL 607
Query: 301 DPI--HEP-PSLP--PEPKTTKLGQRRESSRPV-KPPKKDVPDSQQHPAP 344
P EP P+ P P P T K P PK+ P + + PAP
Sbjct: 608 APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 657
Score = 54.7 bits (130), Expect = 6e-07
Identities = 50/194 (25%), Positives = 67/194 (34%), Gaps = 37/194 (19%)
Query: 183 RKETGTAKPGVSTV--PNTTQASTPPQTQTPQPNPPPVQATP----HPFPAVT------- 229
+ ET T P ++T P T P T +P P +++ P P P T
Sbjct: 293 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 352
Query: 230 ----PDLIVQTPVMTVVPPQPLQTPPPVPPQ----PQPPPAPAPQPVQSHPPIIAATPQP 281
P + T P P T P P P P PAP + P P P
Sbjct: 353 KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 412
Query: 282 VKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKP----PKKDVPD 337
K+ PTT +P P+ P EP T P KP PK+ P
Sbjct: 413 TTPKEPTPTTPKEPAPTTKEP---APTTPKEPAPT---------APKKPAPTTPKEPAPT 460
Query: 338 SQQHPAPEKSSKVS 351
+ + PAP + + S
Sbjct: 461 TPKEPAPTTTKEPS 474
Score = 54.7 bits (130), Expect = 6e-07
Identities = 40/157 (25%), Positives = 56/157 (35%), Gaps = 6/157 (3%)
Query: 197 PNTTQASTPPQTQTPQPNPPPVQA--TPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVP 254
P TT+ P + P P P A TP TP+ + T P P + P P
Sbjct: 553 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 612
Query: 255 PQPQP--PPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPE 312
+P P P PAP ++ P P P K+ PTT P P+ P
Sbjct: 613 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT--PKETAPTTPKG 670
Query: 313 PKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSK 349
T L + ++ PK+ P + + P K
Sbjct: 671 TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 707
Score = 53.5 bits (127), Expect = 1e-06
Identities = 45/170 (26%), Positives = 57/170 (33%), Gaps = 19/170 (11%)
Query: 186 TGTAKPGVST----VPNTTQASTPPQTQTPQPNPP--PVQATPHPFPAVTPDLIVQTPVM 239
T KP +T P T + P T+ P P P P TP TP + T
Sbjct: 530 TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT-- 587
Query: 240 TVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTT 299
P+ L P P P P AP + P P P K PTT
Sbjct: 588 ----PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTT 643
Query: 300 IDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSK 349
P P+ P EP T + ++ PK P + + PAP K
Sbjct: 644 --PKEPAPTTPKEPAPTTPKETAPTT-----PKGTAPTTLKEPAPTTPKK 686
Score = 51.2 bits (121), Expect = 7e-06
Identities = 48/188 (25%), Positives = 64/188 (34%), Gaps = 16/188 (8%)
Query: 161 INELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQA 220
+N+ T ET+ K KE T+ ++ T+ P T P P
Sbjct: 237 VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP-TSKVLAKPTPKAE 295
Query: 221 TPHPFPAVT----PDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIA 276
T PA+T P + P +P TP + P P PAP +S P
Sbjct: 296 TTTKGPALTTPKEPTPTTPKEPASTTPKEP--TPTTIKSAPTTPKEPAPTTTKS-APTTP 352
Query: 277 ATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVP 336
P P TK+ PTT + P P TTK PKK P
Sbjct: 353 KEPAPTTTKEPAPTTPKEPAPTT--------TKEPAPTTTKSAPTTPKEPAPTTPKKPAP 404
Query: 337 DSQQHPAP 344
+ + PAP
Sbjct: 405 TTPKEPAP 412
Score = 50.8 bits (120), Expect = 9e-06
Identities = 47/177 (26%), Positives = 64/177 (36%), Gaps = 21/177 (11%)
Query: 186 TGTAKPGVST----VPNTTQASTPPQTQTPQPNPP--PVQATPHPFPAVTPD---LIVQT 236
T KP +T P T + P T+ P P P P T P T + ++
Sbjct: 444 TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS 503
Query: 237 PVMTVVPPQPLQTPPPVP---PQPQP--PPAPAPQPVQSHPPIIAATPQPVKTKKGVKRK 291
T P P T P P +P P P PAP + P P P TKK
Sbjct: 504 APTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTT 563
Query: 292 ADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKP----PKKDVPDSQQHPAP 344
PTT P P+ P+ T ++ + P KP P++ P + + P P
Sbjct: 564 PKEPAPTT--PKETAPT-TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 617
Score = 50.8 bits (120), Expect = 9e-06
Identities = 50/185 (27%), Positives = 62/185 (33%), Gaps = 21/185 (11%)
Query: 184 KETGTAKPGVSTVPNTTQASTPPQTQTPQPNPP----------PVQATPHPFPAVTPDLI 233
KET P T P T + P + P P P P TP TP
Sbjct: 573 KETAPTTPKKLT-PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 631
Query: 234 VQTPVMTVVPPQPLQTPPPVPPQPQP--PPAPAPQPVQSHPPIIAATPQPVKTKK-GVKR 290
P P + P P +P P P AP + P P P KK K
Sbjct: 632 APNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKE 691
Query: 291 KADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRE--SSRPVKP----PKKDVPDSQQHPAP 344
A TTT + P+ P PK T +E + P +P PK P + + PAP
Sbjct: 692 LAPTTTKEPTSTTCDKPA-PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP 750
Query: 345 EKSSK 349
K
Sbjct: 751 TTPKK 755
Score = 50.1 bits (118), Expect = 1e-05
Identities = 50/188 (26%), Positives = 60/188 (31%), Gaps = 19/188 (10%)
Query: 165 PTEETEIMIVQAKGRGRGRKETGT-AKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPH 223
P E T I A + T T + P P T P T TP+ P P
Sbjct: 322 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPA 380
Query: 224 PFPAVTPDLIVQTPVMTV----VPPQPLQTPPPVPPQPQPPPAPAPQPVQSHP-PIIAAT 278
P + + P T P P + P P +P P P P P P
Sbjct: 381 PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE 440
Query: 279 PQPVKTKKGVKRKADTTTPTTIDPIHEPPSLP--PEPKTTKLGQRRESSRPVKPPKKDVP 336
P P KK PTT P P+ P P P TTK P K P
Sbjct: 441 PAPTAPKK--------PAPTT--PKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 490
Query: 337 DSQQHPAP 344
+ + PAP
Sbjct: 491 TTTKEPAP 498
Score = 49.3 bits (116), Expect = 3e-05
Identities = 48/192 (25%), Positives = 62/192 (32%), Gaps = 33/192 (17%)
Query: 188 TAKPGVSTVPNTTQASTPPQ-TQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQP 246
T K T P +TP + T T P P P P P P +P
Sbjct: 398 TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP 457
Query: 247 LQTPPPVP-------PQPQPPPAPAPQPVQSHP--------------PIIAATPQPVKTK 285
T P P P P P PAP +S P P P P TK
Sbjct: 458 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 517
Query: 286 KGV----KRKADTTT--PTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQ 339
+ K A TT P P P+ P EP T + ++ PK+ P +
Sbjct: 518 EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTT-----PKEPAPTTP 572
Query: 340 QHPAPEKSSKVS 351
+ AP K++
Sbjct: 573 KETAPTTPKKLT 584
Score = 48.5 bits (114), Expect = 4e-05
Identities = 50/195 (25%), Positives = 63/195 (32%), Gaps = 22/195 (11%)
Query: 161 INELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQA 220
I PT E K KE P + P T P T T +P P ++
Sbjct: 330 IKSAPTTPKEPAPTTTKSAPTTPKEPA---PTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 386
Query: 221 TPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQP----PPA-----PAPQPVQSH 271
P TP T P P + P P +P P PA PAP +
Sbjct: 387 AP-----TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 441
Query: 272 PPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEP-PSLPPEP-KTTKLGQRRESSRPVK 329
P P P K+ PTT EP P+ P EP TT + P
Sbjct: 442 APTAPKKPAPTTPKEPAPTTPKEPAPTT---TKEPSPTTPKEPAPTTTKSAPTTTKEPAP 498
Query: 330 PPKKDVPDSQQHPAP 344
K P + + P+P
Sbjct: 499 TTTKSAPTTPKEPSP 513
Score = 48.1 bits (113), Expect = 6e-05
Identities = 45/157 (28%), Positives = 56/157 (35%), Gaps = 9/157 (5%)
Query: 195 TVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQT---PVMTVVPPQPLQTPP 251
T P T + + P + P P P A P T + T P T P T P
Sbjct: 663 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT-PKGTAPTTP 721
Query: 252 PVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKK-GVKRKADTTTPTTIDPIHEPPSLP 310
P P P PAP + P P P KK K A TTT + P+ P
Sbjct: 722 KEP-APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA-P 779
Query: 311 PEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKS 347
PK T +E + PKK P + + P P S
Sbjct: 780 TTPKETAPTTPKEPAPTT--PKKPAPTTPETPPPTTS 814
Score = 47.8 bits (112), Expect = 7e-05
Identities = 40/165 (24%), Positives = 58/165 (35%), Gaps = 17/165 (10%)
Query: 181 RGRKETGTAKPGVST----VPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQT 236
+G T +P +T P T + + P + P P P A P T T
Sbjct: 714 KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP-TST 772
Query: 237 PVMTVVPPQPLQTPPPVPPQPQP--PPAPAPQPVQSHPPIIAATPQPVKTKK--GVKRKA 292
P P +T P P +P P P PAP ++ PP + P TK+ + +
Sbjct: 773 TSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 832
Query: 293 DTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPD 337
D +TP S P PK + + K P P+
Sbjct: 833 DESTPEL--------SAEPTPKALENSPKEPGVPTTKTPAATKPE 869
Score = 47.0 bits (110), Expect = 1e-04
Identities = 45/177 (25%), Positives = 55/177 (31%), Gaps = 29/177 (16%)
Query: 202 ASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPP-----PVPPQ 256
A T P+ P P TP TP T P P T P P P
Sbjct: 624 APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTT 683
Query: 257 PQPP------------------PAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPT 298
P+ P PAP + P P P K+ T PT
Sbjct: 684 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 743
Query: 299 TI-DPIHEPPSLPP----EPKTTKLGQRRESSRPV-KPPKKDVPDSQQHPAPEKSSK 349
T+ +P P P P TTK S +P PK+ P + + PAP K
Sbjct: 744 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK 800
Score = 44.7 bits (104), Expect = 6e-04
Identities = 47/189 (24%), Positives = 62/189 (32%), Gaps = 30/189 (15%)
Query: 184 KETGTAKPGVSTVPNTTQASTPPQTQTPQPNP---------------PPVQATPHPFPAV 228
KET P T P T + P + P P P TP
Sbjct: 661 KETAPTTPK-GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 719
Query: 229 TPDLIVQTPVMTVVPPQPLQTPPPVPPQPQP--PPAPAPQ---PVQSHPPIIAATPQPVK 283
TP T P P T P +P P P PAP+ P + P + +P
Sbjct: 720 TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 779
Query: 284 TKKGVKRKADTT--TPTTIDPIHEPPSLP--PEPKTTKLGQRRESSRPV---KPPKKDVP 336
T K A TT P P P+ P P P T+++ + P K P + P
Sbjct: 780 TTP--KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP 837
Query: 337 DSQQHPAPE 345
+ P P+
Sbjct: 838 ELSAEPTPK 846
Score = 42.7 bits (99), Expect = 0.002
Identities = 38/137 (27%), Positives = 49/137 (35%), Gaps = 5/137 (3%)
Query: 181 RGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMT 240
+G T + KP +T T A T P+ P P TP P T + V TP T
Sbjct: 767 KGPTSTTSDKPAPTTPKET--APTTPKEPAPTTPKKPAPTTPETPPPTTSE--VSTPTTT 822
Query: 241 VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI 300
P ++P P+ P P P + T P TK + A T T
Sbjct: 823 KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT-TER 881
Query: 301 DPIHEPPSLPPEPKTTK 317
D P + PK TK
Sbjct: 882 DLRTTPETTTAAPKMTK 898
Score = 40.0 bits (92), Expect = 0.015
Identities = 91/463 (19%), Positives = 159/463 (34%), Gaps = 68/463 (14%)
Query: 458 PDEPEEPVVAVSSPAVPPPT--KVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQ 515
P P+EP A ++P P PT K AP + ++ + + +T + +
Sbjct: 641 PTTPKEP--APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 698
Query: 516 EQLKAVHEQLAALS----------QPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKA 565
E ++ A + +P PK+ + ++ KK
Sbjct: 699 EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 758
Query: 566 KEPPPKKTKKNNSSNSN------------VSKKEPAPMK-SKPPPTYESEEEDKCKPMSY 612
KE P TK S+ S+ + KEPAP KP PT +S
Sbjct: 759 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 818
Query: 613 EEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVT 672
+ I+K P E + S EP+ K E T K + E T
Sbjct: 819 PTTTKEPTTIHKSPDESTPEL-----SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 873
Query: 673 SCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSES---------SSSDSEDSE----- 718
+ + + + + KM +++ +E ++ES +S+ ++D+
Sbjct: 874 AKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKIT 933
Query: 719 ----TEMAPK--SKKKGHPGRE-----QKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPP 767
T +APK + KK E ++ +A P PQ+P P++P
Sbjct: 934 TLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTST 993
Query: 768 PPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIA---TQVPVLEPQLPGSVFDPIGHFT 824
P+ + P P+ + + + +P IA Q Q P S + +
Sbjct: 994 KKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKS 1053
Query: 825 QPI----LHLPQPELPPHLPQP---PEHSTPPHL-NQHAVVSP 859
+ P L PH+ P P+ P + NQ +++P
Sbjct: 1054 EDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINP 1096
Score = 38.1 bits (87), Expect = 0.058
Identities = 35/147 (23%), Positives = 52/147 (35%), Gaps = 5/147 (3%)
Query: 181 RGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMT 240
R ET TA P ++ TT T T T P L T
Sbjct: 884 RTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPK 943
Query: 241 VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI 300
V + T + +P+ P + S A TP+P K K K+ T P T+
Sbjct: 944 VTTTKKTITTTEIMNKPEETAKPKDRATNSK----ATTPKPQKPTKAPKKPTSTKKPKTM 999
Query: 301 DPIHEPPSLP-PEPKTTKLGQRRESSR 326
+ +P + P P T+ + + +SR
Sbjct: 1000 PRVRKPKTTPTPRKMTSTMPELNPTSR 1026
Score = 36.2 bits (82), Expect = 0.22
Identities = 24/104 (23%), Positives = 46/104 (44%), Gaps = 5/104 (4%)
Query: 1156 DVGRPVIRPPEQNAPPPGAPD---KDKQKQEPKTP--VAPKKDLKIKNMGSWASLVQKHP 1210
+V P P + APPP K K+ PK P KK ++ + + S+ +
Sbjct: 65 EVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQE 124
Query: 1211 TTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKER 1254
++ SS++ SSS + + + + RE K + + +K + +
Sbjct: 125 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTK 168
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 118 bits (295), Expect = 4e-26
Identities = 166/796 (20%), Positives = 269/796 (33%), Gaps = 85/796 (10%)
Query: 453 RFAKMPDEPEEPVVAVSSPAVPPPTKVVAPPS-SSDSSSDSSSDSDSSTDDSEEERAQRL 511
++ K + E V +P PP +K PPS +S + ++ S + + ++
Sbjct: 92 KYDKCCPDYESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIES 151
Query: 512 AELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHK---RKEEVEENKKSKAKEP 568
E+ E+ Q ++ S + K K K ++ +K +V++NKK++ K+
Sbjct: 152 EEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKK 211
Query: 569 PPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGE 628
P K + + S + + K P T ++ +S K + IN
Sbjct: 212 PTPKPPVVDEAGSGLDNGD---FKVTTPDTSTTQH----NKVSTSPKITTAKPINP---- 260
Query: 629 KLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDV 688
PSL ++ E K +T+ E T
Sbjct: 261 ------------RPSLPPNSDTSKETSLTVNKETTVETKETTTT---------------- 292
Query: 689 IAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQ 748
+K E +S++ + S + S ++AP SK P K +
Sbjct: 293 ----NKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP--TPKAETTTKGPALTT 346
Query: 749 APAPVPQQPPPPPQQPPPPPPPQQ-QQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPV 807
P P P P P P P + P P P ++AP P P +
Sbjct: 347 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 406
Query: 808 LEPQ--LPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNA 865
P+ P + +P T+ P+ E P P+ P +TP + A +P
Sbjct: 407 TTPKEPAPTTTKEPAPTTTKSAPTTPK-EPAPTTPKKPAPTTP---KEPAPTTPKEPTPT 462
Query: 866 LPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDE------EPP 919
P++P+ + A PK P A TP P P + P E + P
Sbjct: 463 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP 522
Query: 920 APPLTSMQMQLYLQ---QLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQ----LQQ 972
AP T + K P TP PS +P P P P P+ ++ +
Sbjct: 523 APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 582
Query: 973 QPPPPPPPQPQPPPQQQHQP--PPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPP 1030
+P P P +P P ++ P P P P + + + P + P ++P P
Sbjct: 583 EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAP 642
Query: 1031 PQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQ 1090
P + +P +P T AP+ +P + + T P
Sbjct: 643 TTPEELAPTTPEEPTPT-TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT- 700
Query: 1091 PKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRP 1150
PK+ P L K +P +P L P K P S P P
Sbjct: 701 PKETAPTTPKGTAPTTL------KEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTP 754
Query: 1151 E-MKPVDVGRPVIRPPEQNAP--PPGAPDKDKQKQEPKTP--VAPKKDLKIKNMGSWASL 1205
+ P P P++ AP P G ++ P TP APK+ G ++
Sbjct: 755 KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTT 814
Query: 1206 VQK-HPTTPSSTAKSS 1220
K PTTP TA ++
Sbjct: 815 SDKPAPTTPKETAPTT 830
Score = 105 bits (262), Expect = 3e-22
Identities = 157/756 (20%), Positives = 253/756 (33%), Gaps = 90/756 (11%)
Query: 464 PVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHE 523
P + + P P P+ PP+S S S + + +T +++E +Q +
Sbjct: 250 PKITTAKPINPRPS---LPPNSDTSKETSLTVNKETTVETKETTTTN-----KQTSTDGK 301
Query: 524 QLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNV 583
+ ++ Q+ K KD K K + E K A P + T ++
Sbjct: 302 EKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAST 361
Query: 584 SKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPS 643
+ KEP P K PT E + ++ + K P +EP+
Sbjct: 362 TPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT--------PKEPA 413
Query: 644 LKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSES 703
P+T +E T K P K A ++ K ++
Sbjct: 414 -----------------PTTTKEPAPTTT-----KSAPTTPKEP--APTTPKKPAPTTPK 449
Query: 704 ESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPV-PQQPPPPPQ 762
E + + + + E AP +K+ P K PAP P++P P
Sbjct: 450 EPAPTTPKEPTPTTPKEPAPTTKE---PAPTTPKE-----------PAPTAPKKPAPTTP 495
Query: 763 QPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGH 822
+ P P P++ P P+ P++ AP S P P P + +P
Sbjct: 496 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 555
Query: 823 FTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSP--PALHNALPQQPSRPSNRAAAL 880
T+ E P P+ P +TP + A +P PA P+ P A
Sbjct: 556 TTKEPAPTTPKEPAPTTPKKPAPTTP---KEPAPTTPKEPAPTTTKKPAPTTPKEPAPTT 612
Query: 881 PPK--PARPPAVSPALTQ--TPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQ 936
P + P P ++P + P P+ P P+ L P P + + +
Sbjct: 613 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA--PTTPEEPTPTTPEEPAPTTPK 670
Query: 937 KVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRP 996
P TP P+ +P P P P P+ ++ P P P P P
Sbjct: 671 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 730
Query: 997 VHLQPM----QFSTHIQQPPP--PQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHK 1050
L P ST +P P P+G P P ++P P P +P +P K
Sbjct: 731 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP---KEPAPTTPKEPAPTTPKGTAPTTLK 787
Query: 1051 SDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSP--PQQNVQPKKQELRAASVVQPQPLV 1108
+P T + AP L + + + +P P++ +E + +P P
Sbjct: 788 -EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTT 846
Query: 1109 ----VVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRP 1164
++ +P EP + P+ PE P P+ E P + G P +
Sbjct: 847 PETPPPTTSEVSTPTTTKEPTTIHKSPD-ESTPELSAEPT--PKALENSPKEPGVPTTKT 903
Query: 1165 PEQNAPPPGAPDKDKQKQE-----PKTPVAPKKDLK 1195
P P KDK + P+T A K K
Sbjct: 904 PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTK 939
Score = 57.4 bits (137), Expect = 9e-08
Identities = 49/176 (27%), Positives = 61/176 (34%), Gaps = 21/176 (11%)
Query: 186 TGTAKPGVSTV---PNTTQASTPPQTQTPQPNPP--PVQATPHPFPAVTPDLIVQTPVMT 240
T T +P +T P T + P + P P P P TP TP + P T
Sbjct: 415 TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP----KEPAPT 470
Query: 241 VVPPQPLQTPPPVP-----PQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTT 295
P P P P P P P PAP + P P P K+ +
Sbjct: 471 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 530
Query: 296 TPTTIDP----IHEPPSLP--PEPKTTKLGQRRESSRPV-KPPKKDVPDSQQHPAP 344
TT +P P+ P P P TTK P PKK P + + PAP
Sbjct: 531 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 586
Score = 55.5 bits (132), Expect = 4e-07
Identities = 49/170 (28%), Positives = 61/170 (35%), Gaps = 14/170 (8%)
Query: 186 TGTAKPGVSTV---PNTTQASTPPQTQTPQPNPP--PVQATPHPFPAVTPDLIVQTPVMT 240
T T +P +T P T + +P T+ P P P P TP TP T T
Sbjct: 532 TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT---T 588
Query: 241 VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI 300
P P T P P P+ P P+ P P K K TTP +
Sbjct: 589 PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL 648
Query: 301 DPI--HEP-PSLP--PEPKTTKLGQRRESSRPV-KPPKKDVPDSQQHPAP 344
P EP P+ P P P T K P PK+ P + + PAP
Sbjct: 649 APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 698
Score = 54.7 bits (130), Expect = 6e-07
Identities = 50/194 (25%), Positives = 67/194 (34%), Gaps = 37/194 (19%)
Query: 183 RKETGTAKPGVSTV--PNTTQASTPPQTQTPQPNPPPVQATP----HPFPAVT------- 229
+ ET T P ++T P T P T +P P +++ P P P T
Sbjct: 334 KAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 393
Query: 230 ----PDLIVQTPVMTVVPPQPLQTPPPVPPQ----PQPPPAPAPQPVQSHPPIIAATPQP 281
P + T P P T P P P P PAP + P P P
Sbjct: 394 KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 453
Query: 282 VKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKP----PKKDVPD 337
K+ PTT +P P+ P EP T P KP PK+ P
Sbjct: 454 TTPKEPTPTTPKEPAPTTKEP---APTTPKEPAPT---------APKKPAPTTPKEPAPT 501
Query: 338 SQQHPAPEKSSKVS 351
+ + PAP + + S
Sbjct: 502 TPKEPAPTTTKEPS 515
Score = 54.7 bits (130), Expect = 6e-07
Identities = 40/157 (25%), Positives = 56/157 (35%), Gaps = 6/157 (3%)
Query: 197 PNTTQASTPPQTQTPQPNPPPVQA--TPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVP 254
P TT+ P + P P P A TP TP+ + T P P + P P
Sbjct: 594 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 653
Query: 255 PQPQP--PPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPE 312
+P P P PAP ++ P P P K+ PTT P P+ P
Sbjct: 654 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT--PKETAPTTPKG 711
Query: 313 PKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSK 349
T L + ++ PK+ P + + P K
Sbjct: 712 TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDK 748
Score = 53.5 bits (127), Expect = 1e-06
Identities = 45/170 (26%), Positives = 57/170 (33%), Gaps = 19/170 (11%)
Query: 186 TGTAKPGVST----VPNTTQASTPPQTQTPQPNPP--PVQATPHPFPAVTPDLIVQTPVM 239
T KP +T P T + P T+ P P P P TP TP + T
Sbjct: 571 TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT-- 628
Query: 240 TVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTT 299
P+ L P P P P AP + P P P K PTT
Sbjct: 629 ----PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTT 684
Query: 300 IDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSK 349
P P+ P EP T + ++ PK P + + PAP K
Sbjct: 685 --PKEPAPTTPKEPAPTTPKETAPTT-----PKGTAPTTLKEPAPTTPKK 727
Score = 51.2 bits (121), Expect = 7e-06
Identities = 48/188 (25%), Positives = 64/188 (34%), Gaps = 16/188 (8%)
Query: 161 INELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQA 220
+N+ T ET+ K KE T+ ++ T+ P T P P
Sbjct: 278 VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP-TSKVLAKPTPKAE 336
Query: 221 TPHPFPAVT----PDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIA 276
T PA+T P + P +P TP + P P PAP +S P
Sbjct: 337 TTTKGPALTTPKEPTPTTPKEPASTTPKEP--TPTTIKSAPTTPKEPAPTTTKS-APTTP 393
Query: 277 ATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVP 336
P P TK+ PTT + P P TTK PKK P
Sbjct: 394 KEPAPTTTKEPAPTTPKEPAPTT--------TKEPAPTTTKSAPTTPKEPAPTTPKKPAP 445
Query: 337 DSQQHPAP 344
+ + PAP
Sbjct: 446 TTPKEPAP 453
Score = 50.8 bits (120), Expect = 9e-06
Identities = 47/177 (26%), Positives = 64/177 (36%), Gaps = 21/177 (11%)
Query: 186 TGTAKPGVST----VPNTTQASTPPQTQTPQPNPP--PVQATPHPFPAVTPD---LIVQT 236
T KP +T P T + P T+ P P P P T P T + ++
Sbjct: 485 TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS 544
Query: 237 PVMTVVPPQPLQTPPPVP---PQPQP--PPAPAPQPVQSHPPIIAATPQPVKTKKGVKRK 291
T P P T P P +P P P PAP + P P P TKK
Sbjct: 545 APTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTT 604
Query: 292 ADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKP----PKKDVPDSQQHPAP 344
PTT P P+ P+ T ++ + P KP P++ P + + P P
Sbjct: 605 PKEPAPTT--PKETAPT-TPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 658
Score = 50.8 bits (120), Expect = 9e-06
Identities = 50/185 (27%), Positives = 62/185 (33%), Gaps = 21/185 (11%)
Query: 184 KETGTAKPGVSTVPNTTQASTPPQTQTPQPNPP----------PVQATPHPFPAVTPDLI 233
KET P T P T + P + P P P P TP TP
Sbjct: 614 KETAPTTPKKLT-PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 672
Query: 234 VQTPVMTVVPPQPLQTPPPVPPQPQP--PPAPAPQPVQSHPPIIAATPQPVKTKK-GVKR 290
P P + P P +P P P AP + P P P KK K
Sbjct: 673 APNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKE 732
Query: 291 KADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRE--SSRPVKP----PKKDVPDSQQHPAP 344
A TTT + P+ P PK T +E + P +P PK P + + PAP
Sbjct: 733 LAPTTTKEPTSTTCDKPA-PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP 791
Query: 345 EKSSK 349
K
Sbjct: 792 TTPKK 796
Score = 50.1 bits (118), Expect = 1e-05
Identities = 50/188 (26%), Positives = 60/188 (31%), Gaps = 19/188 (10%)
Query: 165 PTEETEIMIVQAKGRGRGRKETGT-AKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPH 223
P E T I A + T T + P P T P T TP+ P P
Sbjct: 363 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPA 421
Query: 224 PFPAVTPDLIVQTPVMTV----VPPQPLQTPPPVPPQPQPPPAPAPQPVQSHP-PIIAAT 278
P + + P T P P + P P +P P P P P P
Sbjct: 422 PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE 481
Query: 279 PQPVKTKKGVKRKADTTTPTTIDPIHEPPSLP--PEPKTTKLGQRRESSRPVKPPKKDVP 336
P P KK PTT P P+ P P P TTK P K P
Sbjct: 482 PAPTAPKK--------PAPTT--PKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 531
Query: 337 DSQQHPAP 344
+ + PAP
Sbjct: 532 TTTKEPAP 539
Score = 49.3 bits (116), Expect = 3e-05
Identities = 48/192 (25%), Positives = 62/192 (32%), Gaps = 33/192 (17%)
Query: 188 TAKPGVSTVPNTTQASTPPQ-TQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQP 246
T K T P +TP + T T P P P P P P +P
Sbjct: 439 TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP 498
Query: 247 LQTPPPVP-------PQPQPPPAPAPQPVQSHP--------------PIIAATPQPVKTK 285
T P P P P P PAP +S P P P P TK
Sbjct: 499 APTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 558
Query: 286 KGV----KRKADTTT--PTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQ 339
+ K A TT P P P+ P EP T + ++ PK+ P +
Sbjct: 559 EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTT-----PKEPAPTTP 613
Query: 340 QHPAPEKSSKVS 351
+ AP K++
Sbjct: 614 KETAPTTPKKLT 625
Score = 48.5 bits (114), Expect = 4e-05
Identities = 50/195 (25%), Positives = 63/195 (32%), Gaps = 22/195 (11%)
Query: 161 INELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQA 220
I PT E K KE P + P T P T T +P P ++
Sbjct: 371 IKSAPTTPKEPAPTTTKSAPTTPKEPA---PTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 427
Query: 221 TPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQP----PPA-----PAPQPVQSH 271
P TP T P P + P P +P P PA PAP +
Sbjct: 428 AP-----TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 482
Query: 272 PPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEP-PSLPPEP-KTTKLGQRRESSRPVK 329
P P P K+ PTT EP P+ P EP TT + P
Sbjct: 483 APTAPKKPAPTTPKEPAPTTPKEPAPTT---TKEPSPTTPKEPAPTTTKSAPTTTKEPAP 539
Query: 330 PPKKDVPDSQQHPAP 344
K P + + P+P
Sbjct: 540 TTTKSAPTTPKEPSP 554
Score = 48.1 bits (113), Expect = 6e-05
Identities = 45/157 (28%), Positives = 56/157 (35%), Gaps = 9/157 (5%)
Query: 195 TVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQT---PVMTVVPPQPLQTPP 251
T P T + + P + P P P A P T + T P T P T P
Sbjct: 704 TAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT-PKGTAPTTP 762
Query: 252 PVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKK-GVKRKADTTTPTTIDPIHEPPSLP 310
P P P PAP + P P P KK K A TTT + P+ P
Sbjct: 763 KEP-APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA-P 820
Query: 311 PEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKS 347
PK T +E + PKK P + + P P S
Sbjct: 821 TTPKETAPTTPKEPAPTT--PKKPAPTTPETPPPTTS 855
Score = 47.8 bits (112), Expect = 7e-05
Identities = 40/165 (24%), Positives = 58/165 (35%), Gaps = 17/165 (10%)
Query: 181 RGRKETGTAKPGVST----VPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQT 236
+G T +P +T P T + + P + P P P A P T T
Sbjct: 755 KGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP-TST 813
Query: 237 PVMTVVPPQPLQTPPPVPPQPQP--PPAPAPQPVQSHPPIIAATPQPVKTKK--GVKRKA 292
P P +T P P +P P P PAP ++ PP + P TK+ + +
Sbjct: 814 TSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 873
Query: 293 DTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPD 337
D +TP S P PK + + K P P+
Sbjct: 874 DESTPEL--------SAEPTPKALENSPKEPGVPTTKTPAATKPE 910
Score = 47.0 bits (110), Expect = 1e-04
Identities = 45/177 (25%), Positives = 55/177 (31%), Gaps = 29/177 (16%)
Query: 202 ASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPP-----PVPPQ 256
A T P+ P P TP TP T P P T P P P
Sbjct: 665 APTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTT 724
Query: 257 PQPP------------------PAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPT 298
P+ P PAP + P P P K+ T PT
Sbjct: 725 PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 784
Query: 299 TI-DPIHEPPSLPP----EPKTTKLGQRRESSRPV-KPPKKDVPDSQQHPAPEKSSK 349
T+ +P P P P TTK S +P PK+ P + + PAP K
Sbjct: 785 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKK 841
Score = 44.7 bits (104), Expect = 6e-04
Identities = 47/189 (24%), Positives = 62/189 (32%), Gaps = 30/189 (15%)
Query: 184 KETGTAKPGVSTVPNTTQASTPPQTQTPQPNP---------------PPVQATPHPFPAV 228
KET P T P T + P + P P P TP
Sbjct: 702 KETAPTTPK-GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 760
Query: 229 TPDLIVQTPVMTVVPPQPLQTPPPVPPQPQP--PPAPAPQ---PVQSHPPIIAATPQPVK 283
TP T P P T P +P P P PAP+ P + P + +P
Sbjct: 761 TPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 820
Query: 284 TKKGVKRKADTT--TPTTIDPIHEPPSLP--PEPKTTKLGQRRESSRPV---KPPKKDVP 336
T K A TT P P P+ P P P T+++ + P K P + P
Sbjct: 821 TTP--KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTP 878
Query: 337 DSQQHPAPE 345
+ P P+
Sbjct: 879 ELSAEPTPK 887
Score = 42.7 bits (99), Expect = 0.002
Identities = 38/137 (27%), Positives = 49/137 (35%), Gaps = 5/137 (3%)
Query: 181 RGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMT 240
+G T + KP +T T A T P+ P P TP P T + V TP T
Sbjct: 808 KGPTSTTSDKPAPTTPKET--APTTPKEPAPTTPKKPAPTTPETPPPTTSE--VSTPTTT 863
Query: 241 VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI 300
P ++P P+ P P P + T P TK + A T T
Sbjct: 864 KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKT-TER 922
Query: 301 DPIHEPPSLPPEPKTTK 317
D P + PK TK
Sbjct: 923 DLRTTPETTTAAPKMTK 939
Score = 40.0 bits (92), Expect = 0.015
Identities = 91/463 (19%), Positives = 159/463 (34%), Gaps = 68/463 (14%)
Query: 458 PDEPEEPVVAVSSPAVPPPT--KVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQ 515
P P+EP A ++P P PT K AP + ++ + + +T + +
Sbjct: 682 PTTPKEP--APTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 739
Query: 516 EQLKAVHEQLAALS----------QPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKA 565
E ++ A + +P PK+ + ++ KK
Sbjct: 740 EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 799
Query: 566 KEPPPKKTKKNNSSNSN------------VSKKEPAPMK-SKPPPTYESEEEDKCKPMSY 612
KE P TK S+ S+ + KEPAP KP PT +S
Sbjct: 800 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 859
Query: 613 EEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVT 672
+ I+K P E + S EP+ K E T K + E T
Sbjct: 860 PTTTKEPTTIHKSPDESTPEL-----SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 914
Query: 673 SCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSSES---------SSSDSEDSE----- 718
+ + + + + KM +++ +E ++ES +S+ ++D+
Sbjct: 915 AKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKIT 974
Query: 719 ----TEMAPK--SKKKGHPGRE-----QKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPP 767
T +APK + KK E ++ +A P PQ+P P++P
Sbjct: 975 TLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTST 1034
Query: 768 PPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIA---TQVPVLEPQLPGSVFDPIGHFT 824
P+ + P P+ + + + +P IA Q Q P S + +
Sbjct: 1035 KKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKS 1094
Query: 825 QPI----LHLPQPELPPHLPQP---PEHSTPPHL-NQHAVVSP 859
+ P L PH+ P P+ P + NQ +++P
Sbjct: 1095 EDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVPNQGIIINP 1137
Score = 38.1 bits (87), Expect = 0.058
Identities = 35/147 (23%), Positives = 52/147 (35%), Gaps = 5/147 (3%)
Query: 181 RGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMT 240
R ET TA P ++ TT T T T P L T
Sbjct: 925 RTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPK 984
Query: 241 VVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI 300
V + T + +P+ P + S A TP+P K K K+ T P T+
Sbjct: 985 VTTTKKTITTTEIMNKPEETAKPKDRATNSK----ATTPKPQKPTKAPKKPTSTKKPKTM 1040
Query: 301 DPIHEPPSLP-PEPKTTKLGQRRESSR 326
+ +P + P P T+ + + +SR
Sbjct: 1041 PRVRKPKTTPTPRKMTSTMPELNPTSR 1067
Score = 36.2 bits (82), Expect = 0.22
Identities = 24/104 (23%), Positives = 46/104 (44%), Gaps = 5/104 (4%)
Query: 1156 DVGRPVIRPPEQNAPPPGAPD---KDKQKQEPKTP--VAPKKDLKIKNMGSWASLVQKHP 1210
+V P P + APPP K K+ PK P KK ++ + + S+ +
Sbjct: 106 EVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQE 165
Query: 1211 TTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKER 1254
++ SS++ SSS + + + + RE K + + +K + +
Sbjct: 166 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTK 209
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 116 bits (290), Expect = 2e-25
Identities = 98/306 (32%), Positives = 117/306 (38%), Gaps = 42/306 (13%)
Query: 748 QAPAPV----PQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIAT 803
Q P+P PQ PPPPP +P PPP Q P PPPP PQ P S P
Sbjct: 37 QGPSPQGGNKPQGPPPPPGKPQGPPP--QGGNKPQGPPPPGKPQGPPPQGDKSRSP---- 90
Query: 804 QVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALH 863
+ P +PQ P P QP+ PP P P+ P N+ PP
Sbjct: 91 RSPPGKPQGP------------PPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKP 138
Query: 864 NALPQQ------PSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEE 917
P Q P P + PP+ P P P P P + PQ +
Sbjct: 139 QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGK 198
Query: 918 PPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPP 977
P PP + + K Q P P + Q Q PPP P P Q + PP
Sbjct: 199 PQGPPPQGDKSRSSQSPPGKPQGPPPQGGN---QPQGPPPPPGKPQGPPPQGGNKPQGPP 255
Query: 978 PPPQPQPPP-------QQQHQPPPRPVHLQPMQFSTHIQQPPPPQG---QQPPHPPPGQQ 1027
PP +PQ PP Q PP +P P Q + Q PPPP G QQP PP GQ
Sbjct: 256 PPGKPQGPPAQGGSKSQSARSPPGKPQG-PPQQEGNNPQGPPPPAGGNPQQPQAPPAGQP 314
Query: 1028 PPPPQP 1033
PP+P
Sbjct: 315 QGPPRP 320
Score = 110 bits (274), Expect = 1e-23
Identities = 102/325 (31%), Positives = 121/325 (37%), Gaps = 61/325 (18%)
Query: 723 PKSKKKGHPGREQKKHHHHHHQQMQQAPAPV------PQQPPPPPQQPPPPPPPQQQQQP 776
P K +G P + K Q P P P+ PP PQ PPP Q Q P
Sbjct: 53 PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPP 112
Query: 777 PPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELP 836
PPP P P Q + PPP +PQ P P G ++ P P
Sbjct: 113 PPPGKPQGPPPQGGNRPQGPPPPG--------KPQGP----PPQGDKSR------SPRSP 154
Query: 837 PHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSP---- 892
P PQ P PP PP PQ P + PP P +P P
Sbjct: 155 PGKPQGP----PPQGGNQPQGPPPP--PGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDK 208
Query: 893 -ALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQ 951
+Q+P P P PPQ + + PP PP K Q P P + +
Sbjct: 209 SRSSQSP--PGKPQGPPPQGGNQPQGPPPPP-------------GKPQGPPPQGGN---K 250
Query: 952 SQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQ---HQPPPRPVHLQPMQFSTHI 1008
Q PPP P P Q + Q PP +PQ PPQQ+ Q PP P P Q
Sbjct: 251 PQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQ----P 306
Query: 1009 QQPPPPQGQQPPHPPPGQQPP-PPQ 1032
Q PP Q Q PP PP G +P PPQ
Sbjct: 307 QAPPAGQPQGPPRPPQGGRPSRPPQ 331
Score = 73.9 bits (180), Expect = 1e-12
Identities = 72/233 (30%), Positives = 84/233 (36%), Gaps = 24/233 (10%)
Query: 949 KVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQ----QQHQPPPRPVHLQPMQF 1004
K Q PPPP P P Q PPPP PQ PPPQ + + PP P Q
Sbjct: 46 KPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG-PPPQGDKSRSPRSPPGKPQGPPPQG 104
Query: 1005 STHIQQPPPPQGQQPPHPPPGQQPP--PPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREA 1062
Q PPPP G+ PP G P PP P KPQ R +S P +
Sbjct: 105 GNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKP----QG 160
Query: 1063 PSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRS 1122
P P + PQ Q PP Q + K Q Q P K SP
Sbjct: 161 PPPQGGNQPQGPPPPPGKPQGPPPQGGK-KPQGPPPPGKPQGPPPQGDKSRSSQSP--PG 217
Query: 1123 EPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAP 1175
+P P PP+ + P P +P+ P G Q PPPG P
Sbjct: 218 KPQGP-----PPQGGNQPQGPPPPPGKPQGPPPQGGN-----KPQGPPPPGKP 260
Score = 67.8 bits (164), Expect = 7e-11
Identities = 68/244 (27%), Positives = 83/244 (34%), Gaps = 31/244 (12%)
Query: 961 PPHPSVQQQLQQQPPPPPPPQPQPPPQQ-----QHQPPPRPVHLQPMQFSTHIQQPPPPQ 1015
P PS Q + Q PPPPP +PQ PP Q Q PPP P Q PP
Sbjct: 36 PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPG 95
Query: 1016 GQQPPHPPPGQQP--PPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQM 1073
Q P P G QP PPP P KPQ P + P P P
Sbjct: 96 KPQGPPPQGGNQPQGPPPPPGKPQ------------GPPPQGGNRPQGPPPPGKPQGPPP 143
Query: 1074 SQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIR-----SEPFSPS 1128
+S + +SPP + P Q P P K P + P P
Sbjct: 144 QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP------GKPQGPPPQGGKKPQGPPPPG 197
Query: 1129 LRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQK-QEPKTP 1187
PP + ++ P +P+ P G PP P G P + K Q P P
Sbjct: 198 KPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 257
Query: 1188 VAPK 1191
P+
Sbjct: 258 GKPQ 261
Score = 51.2 bits (121), Expect = 7e-06
Identities = 56/199 (28%), Positives = 72/199 (36%), Gaps = 27/199 (13%)
Query: 1001 PMQFSTHIQQPPPPQGQQP--PHPPPG--QQPP---------PPQPAKPQQVIQHHHSPR 1047
P + + Q P P G +P P PPPG Q PP PP P KPQ R
Sbjct: 29 PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSR 88
Query: 1048 HHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPL 1107
+S P + P P + PQ Q PP Q + P P
Sbjct: 89 SPRSPPGKP----QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPP- 143
Query: 1108 VVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQ 1167
+ +K SP RS P P + PP+ + P P +P+ P G+ PP
Sbjct: 144 ---QGDKSRSP--RSPPGKP--QGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPP 196
Query: 1168 NAP--PPGAPDKDKQKQEP 1184
P PP DK + Q P
Sbjct: 197 GKPQGPPPQGDKSRSSQSP 215
Score = 43.5 bits (101), Expect = 0.001
Identities = 48/202 (23%), Positives = 70/202 (34%), Gaps = 7/202 (3%)
Query: 146 IVLMAEALEKLF-LQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQAST 204
++L++ AL L Q +NE ++E ++ G +G G KP P
Sbjct: 3 LILLSVALLALSSAQNLNEDVSQEESPSLIA--GNPQGPSPQGGNKPQGPPPPPGKPQGP 60
Query: 205 PPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPA 264
PPQ PPP P P ++P P P P P P P
Sbjct: 61 PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 120
Query: 265 PQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRES 324
P P + P P P K + + + +P + P +P PP+ G
Sbjct: 121 PPPQGGNRP--QGPPPPGKPQGPPPQGDKSRSPRS--PPGKPQGPPPQGGNQPQGPPPPP 176
Query: 325 SRPVKPPKKDVPDSQQHPAPEK 346
+P PP + Q P P K
Sbjct: 177 GKPQGPPPQGGKKPQGPPPPGK 198
Score = 37.4 bits (85), Expect = 0.099
Identities = 39/167 (23%), Positives = 53/167 (31%), Gaps = 13/167 (7%)
Query: 178 GRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTP 237
G+ +G G +P P PPQ PPP P P Q+P
Sbjct: 156 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSP 215
Query: 238 VMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTP 297
P P P P P P P P + P P P +G + + +
Sbjct: 216 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP---QGPPPPGKPQGPPAQGGSKSQ 272
Query: 298 TTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAP 344
+ PP P P ++E + P PP + QQ AP
Sbjct: 273 SA----RSPPGKPQGP------PQQEGNNPQGPPPPAGGNPQQPQAP 309
Score = 36.6 bits (83), Expect = 0.17
Identities = 46/192 (23%), Positives = 65/192 (33%), Gaps = 34/192 (17%)
Query: 178 GRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTP 237
G+ +G G +P P Q P ++ P PP + P P P
Sbjct: 116 GKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGK------PQGPPPQGGNQP 169
Query: 238 VMTVVPPQPLQTPPPV-------PPQPQPPPAPAPQPVQSH----PPIIAATPQPVKTKK 286
PP Q PPP PP P P P PQ +S PP PQ +
Sbjct: 170 QGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPP---GKPQGPPPQG 226
Query: 287 GVKRKADTTTPTTID---------PIHEPPSLPPEPKTTKLGQRRESSR-----PVKPPK 332
G + + P P PP P+ + G + +S+R P PP+
Sbjct: 227 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQ 286
Query: 333 KDVPDSQQHPAP 344
++ + Q P P
Sbjct: 287 QEGNNPQGPPPP 298
Score = 33.1 bits (74), Expect = 1.9
Identities = 31/107 (28%), Positives = 40/107 (37%), Gaps = 12/107 (11%)
Query: 178 GRGRGRKETGTAKP-GVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQT 236
G+ +G G +P G P Q P PQ PPP + P + ++
Sbjct: 217 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARS 276
Query: 237 PVMTVVPPQPLQTPPPVPPQPQPPPAPA---PQPVQSHPPIIAATPQ 280
P P +P P PQ PP PA PQ Q+ P A PQ
Sbjct: 277 P-----PGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP---AGQPQ 315
Score = 32.0 bits (71), Expect = 4.2
Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 8/60 (13%)
Query: 717 SETEMAPKSKKKGHPGREQKKHHHH------HHQQMQQAPAPVPQQPPPPPQ--QPPPPP 768
S++ +P K +G P +E + QQ Q PA PQ PP PPQ +P PP
Sbjct: 271 SQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 330
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 115 bits (287), Expect = 4e-25
Identities = 164/612 (26%), Positives = 221/612 (36%), Gaps = 109/612 (17%)
Query: 701 SESESSSES----SSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPA----- 751
S+S+SS +S S +D+ S + P Q +QQ AP
Sbjct: 626 SDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGS 685
Query: 752 -PVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVP-VLE 809
P P PP Q P P PPP P P+ P Q AP + PP T +P VL
Sbjct: 686 VPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLA 745
Query: 810 PQLPGSVFDPIGHFTQPI---------------LHLPQPELPPHL---PQPPEHSTPPHL 851
PQ P P+ P L +PQ L P PQ P P +
Sbjct: 746 PQ-PVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPI 804
Query: 852 NQHAVVS--PPALHN-----ALPQQPSRPSNRAAALPPKPARPPAVSPAL-TQTPLLPQP 903
A + PPAL + P P + + A LP A P SPAL Q LP P
Sbjct: 805 TPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHP 864
Query: 904 ---PMAQPPQVLLEDEEPPAPPLTSMQ----MQLYLQQLQKVQPPTPLLPSVKVQSQPPP 956
P+A P + ++ + P PL ++ L + P P+ P+ Q P
Sbjct: 865 PGAPLAMPCRTIVPN-APATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQ-MAPT 922
Query: 957 PLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQP----PPRPVHLQPMQFSTHIQQPP 1012
+PP PH +VQ P P PPQP PPQ P PP+PV L P Q
Sbjct: 923 DVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPV-LPP-------QPTR 974
Query: 1013 PPQGQQPPHPP-PGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSP 1071
PPQ PP P P Q PPQPA P + P PL H P
Sbjct: 975 PPQPVLPPQPMLPPQPVLPPQPALPVR------------------------PEPLQPHLP 1010
Query: 1072 QMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSE--PFSPSL 1129
+ + + P + A V P V V + SP + P +P L
Sbjct: 1011 EQA-----APAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPEL 1065
Query: 1130 RPEPPKHPESIKAPVH-LPQR-----PEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQE 1183
P+ P ++ A V +P + P P G P I P P +++Q +
Sbjct: 1066 LPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQ 1125
Query: 1184 PKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFR---RAAREKEEREKA 1240
K P P+ S S T+ + S +F R RAAR+ R
Sbjct: 1126 DKPPGLPQ---------SCESYGGSDVTSGKELSDSCEGAFGGGRLEGRAARKHHRRSTR 1176
Query: 1241 LKAQAEHAEKEK 1252
+++ E A + +
Sbjct: 1177 ARSRQERASRPR 1188
Score = 103 bits (256), Expect = 1e-21
Identities = 125/478 (26%), Positives = 175/478 (36%), Gaps = 57/478 (11%)
Query: 744 QQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIAT 803
++ Q +P + PP P Q Q Q PP P P Q P + +A+
Sbjct: 553 KEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSATSLAS 612
Query: 804 QVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALH 863
Q GS +Q + L L P P + P +++ V+
Sbjct: 613 DSTFDSGQ--GSTVYSDSQSSQQSVML--GSLADAAPSPAQCVCSPPVSEGPVLPQSLPS 668
Query: 864 NALPQQPSRPSNRAAALPPKPARPPAV-----SPALTQTPLLPQPPMAQPPQVLLEDEEP 918
QQP+ P PA PP++ PA++ P+LP P P
Sbjct: 669 LGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMP-----TGPGQ 723
Query: 919 PAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQ--QQPPP 976
PAPP L +V P P++P V PP L P QL+ Q P
Sbjct: 724 PAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQA 783
Query: 977 PPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPP-----PQGQQPPHPPP------- 1024
P P Q PPQ PP PV + P+ I PP P PP PPP
Sbjct: 784 PLQPLAQVPPQM----PPIPV-VPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAV 838
Query: 1025 -----GQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSL 1079
PP PA P Q ++ H P + P T + AP+ + + + +L
Sbjct: 839 ILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRT-IVPNAPATIPLLAVAPPGVAAL 897
Query: 1080 THQSP----PQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPK 1135
+ S P Q V P A + V P P V+ +R+ P P+L P+P
Sbjct: 898 SIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQN-------MRATPPQPALPPQPTL 950
Query: 1136 HPESIKAPVHLPQRPEMKPVDVGRP-VIRPPEQNAPP-PGAPDKDKQKQEPKTPVAPK 1191
P+ + LP +P + P V P RPP+ PP P P + +P PV P+
Sbjct: 951 PPQPV-----LPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPE 1003
Score = 61.6 bits (148), Expect = 5e-09
Identities = 64/240 (26%), Positives = 89/240 (37%), Gaps = 51/240 (21%)
Query: 826 PILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPA 885
P+ P PE P P P S PP +Q + L + +QPS +++ P+
Sbjct: 1317 PVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSK--EQPSFLASQQLLSQAGPS 1374
Query: 886 RPPAVSPALTQTPLLPQ-PPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPL 944
PP PA PL P PP+ PQ + AP ++M Q P TP
Sbjct: 1375 NPPGAPPA----PLAPSSPPVTALPQ------DGAAPATSTMPEPASGTASQAGGPGTPQ 1424
Query: 945 LPSVKVQSQPP------------------PPLPPPPHPSVQQQLQQQPPPPPPPQPQPPP 986
+ ++++ P P P P + + P PPP P+P P
Sbjct: 1425 GLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSP 1484
Query: 987 QQQHQPPPRPVHLQP----------MQFSTHIQQPPPPQGQ-QPPHPP-----PGQQPPP 1030
H P+P QP + +T Q P PP G PP PP G+ PPP
Sbjct: 1485 ---HSGTPQPALGQPAPLLPAAVGAVSLATS-QLPSPPLGPTVPPQPPSALESDGEGPPP 1540
Score = 57.0 bits (136), Expect = 1e-07
Identities = 134/583 (22%), Positives = 190/583 (32%), Gaps = 120/583 (20%)
Query: 757 PPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQ-AAPAMKSSPPPFIATQVPVLEPQLPGS 815
P PP PP P P PP ++PQ AAPA + P P T P P
Sbjct: 1373 PSNPPGAPPAPLAPSS-------PPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQG 1425
Query: 816 VFDPIGHFTQPILHLPQPE---------LPPHLPQPPEHSTPPHLNQHAVVSPPALHNAL 866
+ + +QP+ + L P P P ST + PPA
Sbjct: 1426 LTSEL-ETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPE--- 1481
Query: 867 PQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMA-----QPPQVLLEDEEPPAP 921
P + + A P P P AV T LP PP+ QPP L D E P P
Sbjct: 1482 -PSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPP 1540
Query: 922 -------PLTSMQMQLYLQQLQKVQPPTPLLPSVKVQ-------------SQPPP----- 956
+ S+ +L Q+ P + V+ QP
Sbjct: 1541 RVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGG 1600
Query: 957 --PLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPP- 1013
LPP P +V ++Q PQP ++ P R ++ S+ + P
Sbjct: 1601 DLALPPVPKEAVSGRVQ---------LPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPR 1651
Query: 1014 ---------PQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPS 1064
Q H P P +P +V P PS
Sbjct: 1652 SMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARV-----EPTDRDGGEAGESSAEPPPS 1706
Query: 1065 PLMIHSPQMSQFQSL-------THQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHS 1117
+ Q S Q+L + P QQ+V + + SVV Q E + S
Sbjct: 1707 DMGTVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQ-----DEWTLAS 1761
Query: 1118 PIIRSEPFSPSL-RPEPPKHPESIKAPVHLPQRPEMKPVDVGRPV----------IRPPE 1166
P P + E P P+ +K V Q V VG PV RPP
Sbjct: 1762 PHSLRYSAPPDVYLDEAPSSPD-VKLAVRRAQTASSIEVGVGEPVSSDSGDEGPRARPPV 1820
Query: 1167 Q---NAPPPGAPDKDKQK------QEPKT--PVAPKKDLKIKNMGSWASLVQKHPTTPSS 1215
Q + P G+ D K Q P + P+ ++ S+ H S
Sbjct: 1821 QKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPETPSRVGMKVPTISVTSFH----SQ 1876
Query: 1216 TAKSSSDSFEQFRRAAREKE---EREKALKAQAEHAEKEKERL 1255
++ SSD+ + A +KE REK LK +E ++K+ +
Sbjct: 1877 SSYISSDNDSELEDADIKKELQSLREKHLKEISELQSQQKQEI 1919
Score = 54.3 bits (129), Expect = 8e-07
Identities = 80/330 (24%), Positives = 107/330 (32%), Gaps = 63/330 (19%)
Query: 682 QAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHH 741
QAE+ I +MK + SE + +D P G E+ +
Sbjct: 1240 QAERETFI---EQMKDVMDKAEDMLSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQ--- 1293
Query: 742 HHQQMQQAPAPVPQQPPP----------PPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAP 791
QA APV QQ P + P P P+ P PP Q +AP
Sbjct: 1294 -----SQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEASQDSAP 1348
Query: 792 ----AMKSSPPPFIATQVPVLE---PQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPE 844
P F+A+Q + + PG+ P+ + P+ LPQ P PE
Sbjct: 1349 YKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPE 1408
Query: 845 HSTPPHLNQHAVVSPPALHNAL-PQQPSRPSNRA--------AALPPKPARPPAVSPALT 895
++ +P L + L QP ++ A L P P A S
Sbjct: 1409 PASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDA 1468
Query: 896 QTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLP------SVK 949
P P PP A P P P L P PLLP S+
Sbjct: 1469 SAPREPLPPPAPEPS---PHSGTPQPALGQ---------------PAPLLPAAVGAVSLA 1510
Query: 950 VQSQPPPPLPP--PPHPSVQQQLQQQPPPP 977
P PPL P PP P + + PPP
Sbjct: 1511 TSQLPSPPLGPTVPPQPPSALESDGEGPPP 1540
Score = 51.6 bits (122), Expect = 5e-06
Identities = 46/159 (28%), Positives = 63/159 (39%), Gaps = 36/159 (22%)
Query: 189 AKPGVSTVP-NTTQASTPPQ----TQTPQPNPPPVQATPH----------PFPAVTPDLI 233
A PGV+ + ++ A P Q PQ P V +PH P PA+ P
Sbjct: 890 APPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPT 949
Query: 234 VQTPVMTVVPPQPLQTPPPV-PPQPQPPPAPA--------PQPVQSHPPIIAATPQPVK- 283
+ P V+PPQP P PV PPQP PP P PQPV P + P+P++
Sbjct: 950 L--PPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQP 1007
Query: 284 ---------TKKGVKRKADTTTPTTIDPIHEPPSLPPEP 313
G + P +D + P++P P
Sbjct: 1008 HLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPP 1046
Score = 49.7 bits (117), Expect = 2e-05
Identities = 36/126 (28%), Positives = 48/126 (38%), Gaps = 11/126 (8%)
Query: 222 PHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQP 281
P FP + P + +P TV + P +PPQP PP P P + PP PQP
Sbjct: 913 PAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQP 972
Query: 282 VKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQ-- 339
+ + V P P LPP+P + + P + P SQ
Sbjct: 973 TRPPQPVLPPQPMLPP--------QPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQIL 1024
Query: 340 -QHPAP 344
HPAP
Sbjct: 1025 LGHPAP 1030
Score = 49.3 bits (116), Expect = 3e-05
Identities = 49/150 (32%), Positives = 58/150 (38%), Gaps = 27/150 (18%)
Query: 191 PGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTP 250
P +S P STP T QP PP Q P L TP+ V+ PQP+
Sbjct: 702 PAMSFAPVLPPPSTPMPTGPGQPAPPGQQ---------PPPLAQPTPLPQVLAPQPVVPL 752
Query: 251 PPVPPQPQPPPAPAPQ---PVQSHPPIIAATP-QPVKTKKGVKRKADTTTPTT----IDP 302
PVPP P APA Q P Q P + P QP+ P T ID
Sbjct: 753 QPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDG 812
Query: 303 IHEPPSLPPEPKTTKLGQRRESSRPVKPPK 332
+ PP+LP P T PV PP+
Sbjct: 813 L--PPALPDLPTAT--------VPPVPPPQ 832
Score = 47.4 bits (111), Expect = 1e-04
Identities = 45/165 (27%), Positives = 59/165 (35%), Gaps = 15/165 (9%)
Query: 189 AKPGVSTVPN-----TTQASTP--PQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTV 241
A P ST+P +QA P PQ T + A H P L+V T
Sbjct: 1399 AAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTP 1458
Query: 242 VPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTID 301
P P +P PPPAP P P P P P+ V + T+
Sbjct: 1459 APEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPL-LPAAVGAVSLATSQLPSP 1517
Query: 302 PIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEK 346
P+ P++PP+P + ES PP+ DS EK
Sbjct: 1518 PL--GPTVPPQPPSA-----LESDGEGPPPRVGFVDSTIKSLDEK 1555
Score = 44.3 bits (103), Expect = 8e-04
Identities = 32/100 (32%), Positives = 37/100 (37%), Gaps = 7/100 (7%)
Query: 187 GTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPV------MT 240
G P P Q + PQ PQP P PH P + P V P M
Sbjct: 722 GQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMP 781
Query: 241 VVPPQPL-QTPPPVPPQPQPPPAPAPQPVQSHPPIIAATP 279
P QPL Q PP +PP P PP + PP + P
Sbjct: 782 QAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLP 821
Score = 42.7 bits (99), Expect = 0.002
Identities = 35/138 (25%), Positives = 48/138 (34%), Gaps = 20/138 (14%)
Query: 191 PGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTP 250
P + T A P P P PP P PA++ ++ P P P
Sbjct: 667 PSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPST----PMPTGPG 722
Query: 251 PPVPPQPQPP----PAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPI--- 303
P PP QPP P P PQ V + P++ P P + + P + P+
Sbjct: 723 QPAPPGQQPPPLAQPTPLPQ-VLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMP 781
Query: 304 --------HEPPSLPPEP 313
PP +PP P
Sbjct: 782 QAPLQPLAQVPPQMPPIP 799
Score = 40.8 bits (94), Expect = 0.009
Identities = 44/171 (25%), Positives = 55/171 (32%), Gaps = 36/171 (21%)
Query: 201 QASTPPQTQTPQPNPPPVQATPHPFPAV----TPDLIVQTPVMTVVPPQPLQ-------- 248
QA P Q P P PP+ P P P + P TV P P Q
Sbjct: 782 QAPLQPLAQVP-PQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVIL 840
Query: 249 --TPPPVPPQ-----------PQPPPAPAPQP----VQSHP---PIIAATPQPV---KTK 285
P+PP P PP AP P V + P P++A P V
Sbjct: 841 PSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIH 900
Query: 286 KGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVP 336
V + P P +PP P T R +P PP+ +P
Sbjct: 901 SAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLP 951
Score = 37.0 bits (84), Expect = 0.13
Identities = 64/264 (24%), Positives = 86/264 (32%), Gaps = 34/264 (12%)
Query: 975 PPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQP------PHPPPGQQP 1028
P P P+ PP PP P + ++ P Q P PPG P
Sbjct: 1322 PAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPP 1381
Query: 1029 PPPQPAKP--QQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQ 1086
P P+ P + Q +P ++G +A P Q LT +
Sbjct: 1382 APLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGP--------GTPQGLTSE---L 1430
Query: 1087 QNVQPKKQELRAASVVQPQPLVV-----VKEEKIHSPIIRSEPFSPSLRPEPPKHPESIK 1141
+ QP + A V QPLVV + S S P P P P P S
Sbjct: 1431 ETSQPLAETHEAPLAV--QPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGT 1488
Query: 1142 APVHLPQRPEMKPVDVGRPVI------RPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLK 1195
L Q + P VG + PP PP P + E P D
Sbjct: 1489 PQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDST 1548
Query: 1196 IKNMGS--WASLVQKHPTTPSSTA 1217
IK++ L Q+H T S++A
Sbjct: 1549 IKSLDEKLRTLLYQEHVPTSSASA 1572
Score = 35.8 bits (81), Expect = 0.29
Identities = 49/217 (22%), Positives = 80/217 (36%), Gaps = 44/217 (20%)
Query: 145 DIVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQAST 204
D +L AE + F++++ ++ ++ E M+ + RG + GT+ P +ST T
Sbjct: 1236 DFILQAE--RETFIEQMKDV-MDKAEDMLSEDTDADRG-SDPGTSPPHLSTCG----LGT 1287
Query: 205 PPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPA 264
+++ Q N P + Q V+ + P P P+ P +
Sbjct: 1288 GEESRQSQANAP----------------VYQQNVLHTGKRWFIICPVAEHPAPEAPESSP 1331
Query: 265 PQPVQSHPPIIAATPQPVKTKKGVKRK----ADTTTPTTIDPIHEPPSLPPEPKTTKLGQ 320
P P+ S PP + P K + K + A + P PP PP P
Sbjct: 1332 PLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGP-SNPPGAPPAPLA----- 1385
Query: 321 RRESSRPVKPPKKDVPDSQQHPA----PEKSSKVSEQ 353
P PP +P PA PE +S + Q
Sbjct: 1386 ------PSSPPVTALPQDGAAPATSTMPEPASGTASQ 1416
Score = 34.3 bits (77), Expect = 0.84
Identities = 27/92 (29%), Positives = 37/92 (40%), Gaps = 11/92 (11%)
Query: 209 QTPQPNPPPVQATPHPFPAV----TPDLIVQTP-----VMTVVPPQPLQTPPPVPPQPQP 259
Q P PP P P V P+L+ Q P V V P QT +PP
Sbjct: 1038 QVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPAN-- 1095
Query: 260 PPAPAPQPVQSHPPIIAATPQPVKTKKGVKRK 291
PP P + S P + T +PV+ ++ + K
Sbjct: 1096 PPLPGGPGIASPCPTVQLTVEPVQEEQASQDK 1127
Score = 33.1 bits (74), Expect = 1.9
Identities = 54/212 (25%), Positives = 79/212 (37%), Gaps = 21/212 (9%)
Query: 992 PPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKS 1051
P +P Q + + PP P Q + QP PP+P +P + QH P S
Sbjct: 548 PALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEP-EADQHLLPPTLPTS 606
Query: 1052 -DPYSTGHLREAPSPLMIHSPQMSQFQSL-------THQSPPQQNVQPKKQELRAASVVQ 1103
++ ++ ++S S QS+ SP Q P E + Q
Sbjct: 607 ATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSE--GPVLPQ 664
Query: 1104 PQPLVVVKEEKIHSP--IIRSEPFSPSLRPEPPKH---PESIKAPVHLPQRPEMKPVDVG 1158
P + ++ +P + S P +P+ P +H P APV LP P G
Sbjct: 665 SLPSLGAYQQPTAAPGLPVGSVP-APACPPSLQQHFPDPAMSFAPV-LPPPSTPMPTGPG 722
Query: 1159 RPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAP 1190
+P PP Q PP P Q P+ PV P
Sbjct: 723 QPA--PPGQQPPPLAQPTPLPQVLAPQ-PVVP 751
Score = 32.0 bits (71), Expect = 4.2
Identities = 25/91 (27%), Positives = 36/91 (39%), Gaps = 25/91 (27%)
Query: 747 QQAPAPVPQQPPPPPQQPPPPPPPQ-------------------QQQQPPPPPPPPSMPQ 787
+ A AP PPP P+ P PQ Q P PP P++P
Sbjct: 1466 RDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPP 1525
Query: 788 QAAPAMKS---SPPP---FIATQVPVLEPQL 812
Q A++S PPP F+ + + L+ +L
Sbjct: 1526 QPPSALESDGEGPPPRVGFVDSTIKSLDEKL 1556
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 111 bits (277), Expect = 5e-24
Identities = 215/899 (23%), Positives = 297/899 (33%), Gaps = 218/899 (24%)
Query: 523 EQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSN 582
E+L + + D K +K + +K VEE A P K ++ + +
Sbjct: 25 EELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEE-----ASTPKVNKQGRSEEISES 79
Query: 583 VSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREP 642
S++ AP K+K E++ +P S D++ L G L
Sbjct: 80 ESEETNAPKKTK-------TEQELPRPQS-------PSDLDSLDGRSLN----------- 114
Query: 643 SLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSE 702
+S+P +I+ D + PS P + + D + S +G +
Sbjct: 115 DDGSSDPRDIDQDNRSTSPSIY---------------SPGSVENDSDSSSGLSQGPARPY 159
Query: 703 SESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHH---HHHHQQMQQAPAPVPQQPPP 759
S DS T P++ + HP +H +M QAP P PPP
Sbjct: 160 HPPPLFPPSPQPPDS-TPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAP---PGAPPP 215
Query: 760 PPQQPP---------PPPPPQ-------------QQQQPPPPPP-----------PPSMP 786
PQ P PP P+ +Q PPP P PP+ P
Sbjct: 216 HPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP 275
Query: 787 QQAAPA---MKSSPPPFIATQVPVLEPQLP---------GSVFDPIGHFTQPIL-HLPQP 833
+ S+PPP P + P LP + P G QP+ HLP P
Sbjct: 276 PTTPVGGGNLPSAPPP---ANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSP 332
Query: 834 E--------LPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPA 885
LPP + P + PH A S PA P S S+ AAA +
Sbjct: 333 HAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYS-SSSSSSAAASSSSSS 391
Query: 886 RPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQP----- 940
+ SP L P PP L +PP S+ Q Q P
Sbjct: 392 SSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRL 451
Query: 941 -------PTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQ-- 991
P P PS QS PP+ H QQQ QQQ Q Q QQQH
Sbjct: 452 LANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQ-----QQQQQQQQQQQHHGN 506
Query: 992 --PPPRPVHLQPMQ-FSTHIQQP---PPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHS 1045
PPP P++ S+H P P G P+PP PPP QV
Sbjct: 507 SGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPH----SQVSYSQAG 562
Query: 1046 PRHH--KSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQEL------- 1096
P S S+ + P SP Q + PP V L
Sbjct: 563 PNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGP-QGAPYPFPPVPTVTTSSATLSTVIATV 621
Query: 1097 -------RAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQR 1149
+ AS P P ++ SP P +P P + P +
Sbjct: 622 ASSPAGYKTASPPGPPPY----GKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTS 677
Query: 1150 PEMKP--VDVGRPVIRP-PEQNA---------PPPGAP------DKDKQKQEP------- 1184
P P G P + P P A PPP AP + KQEP
Sbjct: 678 PPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETP 737
Query: 1185 -------KTPVAPKKDLKIKNMGSWASLVQKH----------------PTTPSSTAKSSS 1221
++P P K + + + S ++ KH P S AK +
Sbjct: 738 ESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRA 797
Query: 1222 DSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEAR 1280
D E+ RR A ++ EK E+E+ER R E+ R RE E LE++ + +E R
Sbjct: 798 DLVEKVRREAEQRAREEK---------ERERERER-EKEREREKERELERSVKLAQEGR 846
Score = 109 bits (273), Expect = 2e-23
Identities = 209/874 (23%), Positives = 286/874 (32%), Gaps = 192/874 (21%)
Query: 572 KTKKNNSSNSNVS---KKEPAPM-------KSKPPPTYESEEEDKCKPMSYEEKRQLSLD 621
KT++N S S S K+ P P ++ P S + K + K+ +
Sbjct: 2 KTRQNKDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEE 61
Query: 622 INKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKP 681
+ K GR I +S S + + P + + + E +P + +L+ L
Sbjct: 62 ASTPKVNKQGRSEEISESE--SEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSS 119
Query: 682 QAEKVDVIAGSSKMKGFSSSESESSSESSSSDSED------------------SETEMAP 723
+D S+ +S E+ S+SSS S+ T P
Sbjct: 120 DPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQP 179
Query: 724 KSKKKGHPGREQKKHHHHHH---QQMQQAPAPVPQQPPPPPQQPP---------PPPPPQ 771
++ + HP +H +M QAP P PPP PQ P PP P+
Sbjct: 180 EASFEPHPSVTPTGYHAPMEPPTSRMFQAP---PGAPPPHPQLYPGGTGGVLSGPPMGPK 236
Query: 772 Q-------------QQQPPPPPP-----------PPSMPQQAAPA---MKSSPPPFIATQ 804
+Q PPP P PP+ P + S+PPP
Sbjct: 237 GGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPP---AN 293
Query: 805 VPVLEPQLP---------GSVFDPIGHFTQPIL-HLPQPE--------LPPHLPQPPEHS 846
P + P LP + P G QP+ HLP P LPP + P +
Sbjct: 294 FPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA 353
Query: 847 TPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMA 906
PH A S PA P S S+ AAA + + SP L P
Sbjct: 354 PSPHSLPPASSSAPAPPMRFPYSSSSSSS-AAASSSSSSSSSSASPFPASQALPSYPHSF 412
Query: 907 QPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPT------------PLLPSVKVQSQP 954
PP L +PP S+ Q Q PP P PS QS
Sbjct: 413 PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTA 472
Query: 955 PPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQ----PPPRPVHLQPMQF-STHIQ 1009
PP+ H QQQ QQQ Q Q QQQH PPP P++ S+H
Sbjct: 473 HPPVSTHHHHHQQQQQQQQQQ-----QQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHA 527
Query: 1010 QP---PPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPL 1066
P P G P+PP PPP + P S+ S+ + P
Sbjct: 528 HPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSN--SSSSTSQGSYPC 585
Query: 1067 MIHSPQMSQFQSLTHQSPPQQNVQPKKQEL--------------RAASVVQPQPLVVVKE 1112
SP Q + PP V L + AS P P
Sbjct: 586 SHPSPSQGP-QGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPY----G 640
Query: 1113 EKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKP--VDVGRPVIRP------ 1164
++ SP P +P P + P + P P G P + P
Sbjct: 641 KRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPA 700
Query: 1165 ---------PEQNAPPPGAPDKDKQ-KQEP--------------KTPVAPKKDLKIKNMG 1200
P AP G P Q KQEP ++P P K + + +
Sbjct: 701 GPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHA 760
Query: 1201 SWASLVQKH----------------PTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQ 1244
S ++ KH P S AK +D E+ RR E E+R + K +
Sbjct: 761 SQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRR---EAEQRAREEKER 817
Query: 1245 AEHAEKEKERLRQERMRSREDEDALEQARRAHEE 1278
E+EKER R E+ R E L Q RA E
Sbjct: 818 EREREREKERER-EKERELERSVKLAQEGRAPVE 850
Score = 43.9 bits (102), Expect = 0.001
Identities = 50/196 (25%), Positives = 71/196 (36%), Gaps = 37/196 (18%)
Query: 185 ETGTAKPGVSTVPN----TTQASTPPQTQTPQPNPPPVQATPHPFPAV----TPDLIVQT 236
+ G P VS+ N T+Q S P +P P Q P+PFP V T + T
Sbjct: 560 QAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGP---QGAPYPFPPVPTVTTSSATLST 616
Query: 237 PVMTVVP-PQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTT 295
+ TV P +T P P P AP+P ++ P P + G T
Sbjct: 617 VIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGT 676
Query: 296 TPT-----------TIDPIHEPP-------SLPPEPKTTKLGQ-------RRESSRPVKP 330
+P T+ P PP SLPP P G ++E + +
Sbjct: 677 SPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYET 736
Query: 331 PKKDVPDSQQHPAPEK 346
P+ VP ++ P K
Sbjct: 737 PESPVPPARSPSPPPK 752
Score = 41.6 bits (96), Expect = 0.005
Identities = 39/136 (28%), Positives = 52/136 (38%), Gaps = 10/136 (7%)
Query: 205 PPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAP- 263
PP Q P P +A+ P P+VTP M + Q PP PP P P P
Sbjct: 166 PPSPQPPDSTPRQPEASFEPHPSVTP--TGYHAPMEPPTSRMFQAPPGAPP-PHPQLYPG 222
Query: 264 APQPVQSHPPI---IAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQ 320
V S PP+ V G K+ TTP ++ + P +P TT +G
Sbjct: 223 GTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVG- 281
Query: 321 RRESSRPVKPPKKDVP 336
+ P PP + P
Sbjct: 282 --GGNLPSAPPPANFP 295
Score = 40.8 bits (94), Expect = 0.009
Identities = 29/85 (34%), Positives = 34/85 (40%), Gaps = 8/85 (9%)
Query: 187 GTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQP 246
GT KPG TV PP + P+ PP A P P ++ I Q P P+
Sbjct: 683 GTFKPGSPTVG---PGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPES 739
Query: 247 LQTPPPVPPQPQPPPAPAPQPVQSH 271
PVPP P P P V SH
Sbjct: 740 -----PVPPARSPSPPPKVVDVPSH 759
Score = 40.4 bits (93), Expect = 0.012
Identities = 35/118 (29%), Positives = 40/118 (33%), Gaps = 18/118 (15%)
Query: 243 PPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDP 302
P +P PP PP PQPP + QP S P + TP P T
Sbjct: 155 PARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHA---------PMEPPTSRM 205
Query: 303 IHEPPSL-PPEPKTTKLGQRRESSRPVKPPKKDVPDS--------QQHPAPEKSSKVS 351
PP PP P+ G S P PK S +QHP P VS
Sbjct: 206 FQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVS 263
Score = 38.5 bits (88), Expect = 0.044
Identities = 28/115 (24%), Positives = 56/115 (48%), Gaps = 20/115 (17%)
Query: 459 DEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDD-----------SEEER 507
+ PE PV SP+ PP KVV PS + S+ + D + +
Sbjct: 735 ETPESPVPPARSPS--PPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKL 792
Query: 508 AQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKK 562
A++ A+L E+++ EQ A + K++E++++ +K+ + +++ E+E + K
Sbjct: 793 AKKRADLVEKVRREAEQRA-------REEKEREREREREKEREREKERELERSVK 840
Score = 35.4 bits (80), Expect = 0.38
Identities = 26/96 (27%), Positives = 37/96 (38%), Gaps = 15/96 (15%)
Query: 194 STVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQT---- 249
S+ ++ +S+ + +P P + + PH FP T + P P P Q
Sbjct: 381 SSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQ 440
Query: 250 -PPPVPP--------QPQPPPAPAPQPVQS--HPPI 274
PPP PP P P P QS HPP+
Sbjct: 441 GPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPV 476
Score = 35.0 bits (79), Expect = 0.49
Identities = 42/185 (22%), Positives = 61/185 (32%), Gaps = 38/185 (20%)
Query: 192 GVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDL-----------IVQTPVMT 240
G S P T +TP PPP FP VTP+L +P
Sbjct: 266 GASGAPPTKPPTTPVGGGNLPSAPPPAN-----FPHVTPNLPPPPALRPLNNASASPPGL 320
Query: 241 VVPPQPLQTPPP---------VPPQPQPPPAPAPQPVQSHPPIIAATPQP--------VK 283
P P P P +PP P+ P AP P S PP ++ P P
Sbjct: 321 GAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSP-HSLPPASSSAPAPPMRFPYSSSS 379
Query: 284 TKKGVKRKADTTTPTTIDPIHEPPSLPPEPKT----TKLGQRRESSRPVKPPKKDVPDSQ 339
+ + +++ ++ P +LP P + T L + + +P
Sbjct: 380 SSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWS 439
Query: 340 QHPAP 344
Q P P
Sbjct: 440 QGPPP 444
Score = 32.3 bits (72), Expect = 3.2
Identities = 33/114 (28%), Positives = 38/114 (33%), Gaps = 25/114 (21%)
Query: 188 TAKPGVSTVPNTTQASTPPQTQTPQPN-----------PPPVQATPHPFP---------- 226
TA P VST + Q Q Q Q PPP A PHP
Sbjct: 471 TAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPY 530
Query: 227 AVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQ 280
A++P L P PP P PPP P PV S ++T Q
Sbjct: 531 AMSPSLGSLRPY----PPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQ 580
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 111 bits (277), Expect = 5e-24
Identities = 215/899 (23%), Positives = 297/899 (33%), Gaps = 218/899 (24%)
Query: 523 EQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSN 582
E+L + + D K +K + +K VEE A P K ++ + +
Sbjct: 25 EELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEE-----ASTPKVNKQGRSEEISES 79
Query: 583 VSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREP 642
S++ AP K+K E++ +P S D++ L G L
Sbjct: 80 ESEETNAPKKTK-------TEQELPRPQS-------PSDLDSLDGRSLN----------- 114
Query: 643 SLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSE 702
+S+P +I+ D + PS P + + D + S +G +
Sbjct: 115 DDGSSDPRDIDQDNRSTSPSIY---------------SPGSVENDSDSSSGLSQGPARPY 159
Query: 703 SESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHH---HHHHQQMQQAPAPVPQQPPP 759
S DS T P++ + HP +H +M QAP P PPP
Sbjct: 160 HPPPLFPPSPQPPDS-TPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAP---PGAPPP 215
Query: 760 PPQQPP---------PPPPPQ-------------QQQQPPPPPP-----------PPSMP 786
PQ P PP P+ +Q PPP P PP+ P
Sbjct: 216 HPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP 275
Query: 787 QQAAPA---MKSSPPPFIATQVPVLEPQLP---------GSVFDPIGHFTQPIL-HLPQP 833
+ S+PPP P + P LP + P G QP+ HLP P
Sbjct: 276 PTTPVGGGNLPSAPPP---ANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSP 332
Query: 834 E--------LPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPA 885
LPP + P + PH A S PA P S S+ AAA +
Sbjct: 333 HAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYS-SSSSSSAAASSSSSS 391
Query: 886 RPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQP----- 940
+ SP L P PP L +PP S+ Q Q P
Sbjct: 392 SSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRL 451
Query: 941 -------PTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQ-- 991
P P PS QS PP+ H QQQ QQQ Q Q QQQH
Sbjct: 452 LANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQ-----QQQQQQQQQQQHHGN 506
Query: 992 --PPPRPVHLQPMQ-FSTHIQQP---PPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHS 1045
PPP P++ S+H P P G P+PP PPP QV
Sbjct: 507 SGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPH----SQVSYSQAG 562
Query: 1046 PRHH--KSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQEL------- 1096
P S S+ + P SP Q + PP V L
Sbjct: 563 PNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGP-QGAPYPFPPVPTVTTSSATLSTVIATV 621
Query: 1097 -------RAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQR 1149
+ AS P P ++ SP P +P P + P +
Sbjct: 622 ASSPAGYKTASPPGPPPY----GKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTS 677
Query: 1150 PEMKP--VDVGRPVIRP-PEQNA---------PPPGAP------DKDKQKQEP------- 1184
P P G P + P P A PPP AP + KQEP
Sbjct: 678 PPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETP 737
Query: 1185 -------KTPVAPKKDLKIKNMGSWASLVQKH----------------PTTPSSTAKSSS 1221
++P P K + + + S ++ KH P S AK +
Sbjct: 738 ESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRA 797
Query: 1222 DSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEAR 1280
D E+ RR A ++ EK E+E+ER R E+ R RE E LE++ + +E R
Sbjct: 798 DLVEKVRREAEQRAREEK---------ERERERER-EKEREREKERELERSVKLAQEGR 846
Score = 109 bits (273), Expect = 2e-23
Identities = 209/874 (23%), Positives = 286/874 (32%), Gaps = 192/874 (21%)
Query: 572 KTKKNNSSNSNVS---KKEPAPM-------KSKPPPTYESEEEDKCKPMSYEEKRQLSLD 621
KT++N S S S K+ P P ++ P S + K + K+ +
Sbjct: 2 KTRQNKDSMSMRSGRKKEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEE 61
Query: 622 INKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKP 681
+ K GR I +S S + + P + + + E +P + +L+ L
Sbjct: 62 ASTPKVNKQGRSEEISESE--SEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSS 119
Query: 682 QAEKVDVIAGSSKMKGFSSSESESSSESSSSDSED------------------SETEMAP 723
+D S+ +S E+ S+SSS S+ T P
Sbjct: 120 DPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQP 179
Query: 724 KSKKKGHPGREQKKHHHHHH---QQMQQAPAPVPQQPPPPPQQPP---------PPPPPQ 771
++ + HP +H +M QAP P PPP PQ P PP P+
Sbjct: 180 EASFEPHPSVTPTGYHAPMEPPTSRMFQAP---PGAPPPHPQLYPGGTGGVLSGPPMGPK 236
Query: 772 Q-------------QQQPPPPPP-----------PPSMPQQAAPA---MKSSPPPFIATQ 804
+Q PPP P PP+ P + S+PPP
Sbjct: 237 GGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPP---AN 293
Query: 805 VPVLEPQLP---------GSVFDPIGHFTQPIL-HLPQPE--------LPPHLPQPPEHS 846
P + P LP + P G QP+ HLP P LPP + P +
Sbjct: 294 FPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA 353
Query: 847 TPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMA 906
PH A S PA P S S+ AAA + + SP L P
Sbjct: 354 PSPHSLPPASSSAPAPPMRFPYSSSSSSS-AAASSSSSSSSSSASPFPASQALPSYPHSF 412
Query: 907 QPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPT------------PLLPSVKVQSQP 954
PP L +PP S+ Q Q PP P PS QS
Sbjct: 413 PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTA 472
Query: 955 PPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQ----PPPRPVHLQPMQF-STHIQ 1009
PP+ H QQQ QQQ Q Q QQQH PPP P++ S+H
Sbjct: 473 HPPVSTHHHHHQQQQQQQQQQ-----QQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHA 527
Query: 1010 QP---PPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPL 1066
P P G P+PP PPP + P S+ S+ + P
Sbjct: 528 HPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSN--SSSSTSQGSYPC 585
Query: 1067 MIHSPQMSQFQSLTHQSPPQQNVQPKKQEL--------------RAASVVQPQPLVVVKE 1112
SP Q + PP V L + AS P P
Sbjct: 586 SHPSPSQGP-QGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPY----G 640
Query: 1113 EKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKP--VDVGRPVIRP------ 1164
++ SP P +P P + P + P P G P + P
Sbjct: 641 KRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPA 700
Query: 1165 ---------PEQNAPPPGAPDKDKQ-KQEP--------------KTPVAPKKDLKIKNMG 1200
P AP G P Q KQEP ++P P K + + +
Sbjct: 701 GPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHA 760
Query: 1201 SWASLVQKH----------------PTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQ 1244
S ++ KH P S AK +D E+ RR E E+R + K +
Sbjct: 761 SQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRR---EAEQRAREEKER 817
Query: 1245 AEHAEKEKERLRQERMRSREDEDALEQARRAHEE 1278
E+EKER R E+ R E L Q RA E
Sbjct: 818 EREREREKERER-EKERELERSVKLAQEGRAPVE 850
Score = 43.9 bits (102), Expect = 0.001
Identities = 50/196 (25%), Positives = 71/196 (36%), Gaps = 37/196 (18%)
Query: 185 ETGTAKPGVSTVPN----TTQASTPPQTQTPQPNPPPVQATPHPFPAV----TPDLIVQT 236
+ G P VS+ N T+Q S P +P P Q P+PFP V T + T
Sbjct: 560 QAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGP---QGAPYPFPPVPTVTTSSATLST 616
Query: 237 PVMTVVP-PQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTT 295
+ TV P +T P P P AP+P ++ P P + G T
Sbjct: 617 VIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGT 676
Query: 296 TPT-----------TIDPIHEPP-------SLPPEPKTTKLGQ-------RRESSRPVKP 330
+P T+ P PP SLPP P G ++E + +
Sbjct: 677 SPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYET 736
Query: 331 PKKDVPDSQQHPAPEK 346
P+ VP ++ P K
Sbjct: 737 PESPVPPARSPSPPPK 752
Score = 41.6 bits (96), Expect = 0.005
Identities = 39/136 (28%), Positives = 52/136 (38%), Gaps = 10/136 (7%)
Query: 205 PPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAP- 263
PP Q P P +A+ P P+VTP M + Q PP PP P P P
Sbjct: 166 PPSPQPPDSTPRQPEASFEPHPSVTP--TGYHAPMEPPTSRMFQAPPGAPP-PHPQLYPG 222
Query: 264 APQPVQSHPPI---IAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQ 320
V S PP+ V G K+ TTP ++ + P +P TT +G
Sbjct: 223 GTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVG- 281
Query: 321 RRESSRPVKPPKKDVP 336
+ P PP + P
Sbjct: 282 --GGNLPSAPPPANFP 295
Score = 40.8 bits (94), Expect = 0.009
Identities = 29/85 (34%), Positives = 34/85 (40%), Gaps = 8/85 (9%)
Query: 187 GTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQP 246
GT KPG TV PP + P+ PP A P P ++ I Q P P+
Sbjct: 683 GTFKPGSPTVG---PGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPES 739
Query: 247 LQTPPPVPPQPQPPPAPAPQPVQSH 271
PVPP P P P V SH
Sbjct: 740 -----PVPPARSPSPPPKVVDVPSH 759
Score = 40.4 bits (93), Expect = 0.012
Identities = 35/118 (29%), Positives = 40/118 (33%), Gaps = 18/118 (15%)
Query: 243 PPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDP 302
P +P PP PP PQPP + QP S P + TP P T
Sbjct: 155 PARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHA---------PMEPPTSRM 205
Query: 303 IHEPPSL-PPEPKTTKLGQRRESSRPVKPPKKDVPDS--------QQHPAPEKSSKVS 351
PP PP P+ G S P PK S +QHP P VS
Sbjct: 206 FQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVS 263
Score = 38.5 bits (88), Expect = 0.044
Identities = 28/115 (24%), Positives = 56/115 (48%), Gaps = 20/115 (17%)
Query: 459 DEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDD-----------SEEER 507
+ PE PV SP+ PP KVV PS + S+ + D + +
Sbjct: 735 ETPESPVPPARSPS--PPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKL 792
Query: 508 AQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKK 562
A++ A+L E+++ EQ A + K++E++++ +K+ + +++ E+E + K
Sbjct: 793 AKKRADLVEKVRREAEQRA-------REEKEREREREREKEREREKERELERSVK 840
Score = 35.4 bits (80), Expect = 0.38
Identities = 26/96 (27%), Positives = 37/96 (38%), Gaps = 15/96 (15%)
Query: 194 STVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQT---- 249
S+ ++ +S+ + +P P + + PH FP T + P P P Q
Sbjct: 381 SSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQ 440
Query: 250 -PPPVPP--------QPQPPPAPAPQPVQS--HPPI 274
PPP PP P P P QS HPP+
Sbjct: 441 GPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPV 476
Score = 35.0 bits (79), Expect = 0.49
Identities = 42/185 (22%), Positives = 61/185 (32%), Gaps = 38/185 (20%)
Query: 192 GVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDL-----------IVQTPVMT 240
G S P T +TP PPP FP VTP+L +P
Sbjct: 266 GASGAPPTKPPTTPVGGGNLPSAPPPAN-----FPHVTPNLPPPPALRPLNNASASPPGL 320
Query: 241 VVPPQPLQTPPP---------VPPQPQPPPAPAPQPVQSHPPIIAATPQP--------VK 283
P P P P +PP P+ P AP P S PP ++ P P
Sbjct: 321 GAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSP-HSLPPASSSAPAPPMRFPYSSSS 379
Query: 284 TKKGVKRKADTTTPTTIDPIHEPPSLPPEPKT----TKLGQRRESSRPVKPPKKDVPDSQ 339
+ + +++ ++ P +LP P + T L + + +P
Sbjct: 380 SSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWS 439
Query: 340 QHPAP 344
Q P P
Sbjct: 440 QGPPP 444
Score = 32.3 bits (72), Expect = 3.2
Identities = 33/114 (28%), Positives = 38/114 (33%), Gaps = 25/114 (21%)
Query: 188 TAKPGVSTVPNTTQASTPPQTQTPQPN-----------PPPVQATPHPFP---------- 226
TA P VST + Q Q Q Q PPP A PHP
Sbjct: 471 TAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPY 530
Query: 227 AVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQ 280
A++P L P PP P PPP P PV S ++T Q
Sbjct: 531 AMSPSLGSLRPY----PPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQ 580
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 110 bits (275), Expect = 9e-24
Identities = 107/353 (30%), Positives = 125/353 (35%), Gaps = 95/353 (26%)
Query: 743 HQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIA 802
H + AP P P P PPP PPPPPPP PPP P S P + + S P P
Sbjct: 159 HGAARTAP-PRPNVPAPPPPTPPPPPPPL------PPPLPSSSPIKTP--LVSPPGPLTK 209
Query: 803 TQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPAL 862
+PV+ P P P PP P PP TPP L +V+S A+
Sbjct: 210 GNLPVVAP--------------------PVPCAPPP-PPPPPPPTPPPLPPASVLSDKAV 248
Query: 863 HNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPP 922
L P + PP P PP P L P P +PP PP PP
Sbjct: 249 KPQLA-----PLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPA-----PPPPLPP 298
Query: 923 LTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPP-------PPHPSVQQQLQQQPP 975
S + L P P LP V S+ PPPLPP PP + Q L P
Sbjct: 299 YASCSPRASL--------PAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQAL---PA 347
Query: 976 PPPPPQPQPPPQQQHQ-----------PPPRPVHLQPM-QFSTHIQQPPPPQGQQPPHPP 1023
PP PP QP Q++ PPP P P + S+ QQ P P
Sbjct: 348 PPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQAT---AWTPTQQP 404
Query: 1024 PGQQP----------------------PPPQPAKPQQVIQHHHSPRHHKSDPY 1054
GQ PPP KP Q I PR P+
Sbjct: 405 GGQLRNGSLHIIDDFESKFTFHSVEDFPPPDEYKPCQKIYPSKIPRSRTPGPW 457
Score = 98.2 bits (243), Expect = 5e-20
Identities = 110/408 (26%), Positives = 133/408 (32%), Gaps = 136/408 (33%)
Query: 753 VPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMP-------------------------- 786
+P PPPPP PPPPPP PPPPPPS P
Sbjct: 1 MPVPPPPPPPLPPPPPP-----LGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQ 55
Query: 787 -----------QQAAPAMKSS------------------PP---PFIATQVPVLEPQLPG 814
++AP ++SS PP A PVL P
Sbjct: 56 GTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLR---PA 112
Query: 815 SVFDPIGHFT--QPILHLPQPELPPHL-------PQPPEHSTPPHLNQHAVVSPPALHNA 865
D G T P P P LP P P + A +PP +
Sbjct: 113 GQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVP 172
Query: 866 LPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQP--------PMAQPPQVLLEDEE 917
P P+ P PP P PP S + +TPL+ P P+ PP
Sbjct: 173 APPPPTPPP------PPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPP 226
Query: 918 PPAPPLT-------------SMQMQLYLQQLQKVQPPTPLLP----------------SV 948
PP PP T +++ QL L + PP PLLP
Sbjct: 227 PPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDA 286
Query: 949 KVQSQPPPPLPP------------PPHPSVQQQLQQQPP-PPPPPQPQPPPQ----QQHQ 991
+ PPPPLPP PP P V + PP PP P Q PPQ Q
Sbjct: 287 QEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALP 346
Query: 992 PPPRPVHLQPMQFSTHIQQPPPPQGQ-QPPHPPPGQQPPPPQPAKPQQ 1038
PP P QP +P G+ PP PP + P +K QQ
Sbjct: 347 APPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQ 394
Score = 76.6 bits (187), Expect = 1e-13
Identities = 105/417 (25%), Positives = 145/417 (34%), Gaps = 57/417 (13%)
Query: 778 PPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPP 837
P PPPP P P +PPP + PV DP G + L
Sbjct: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKG----------RSALLA 51
Query: 838 HLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPP-------------KP 884
+ Q +N + + + + R A+ PP +P
Sbjct: 52 DIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRP 111
Query: 885 ARPPAVSPALT-QTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTP 943
A V+ T Q P P P + + PPA P + + + PP P
Sbjct: 112 AGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAH--GAARTAPPRP 169
Query: 944 LLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPP-QQQHQPPPRPVHLQPM 1002
+P+ PPPP PPPP PPP PPP P P + PP P+
Sbjct: 170 NVPA------PPPPTPPPP-----------PPPLPPPLPSSSPIKTPLVSPPGPL----T 208
Query: 1003 QFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAK--PQQVIQHHHSPRHHKSDPYSTGHLR 1060
+ + + PP P PP PPP PPP PA + ++ +P H P L
Sbjct: 209 KGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLP 268
Query: 1061 EAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPII 1120
P + P S Q P + P AS+ P PL V P +
Sbjct: 269 PCGYPGLKAEP-ASPAQDAQEPPAPPPPLPPYASCSPRASLPAP-PLPGVNSSSETPPPL 326
Query: 1121 RSEPFSPSLRPEPPK-HPESIKAPVHLP-QRPEMKPVDVGRPVIRPPEQNAPPPGAP 1175
P SPS + P K +++ AP P +P ++ GRP + N PPP P
Sbjct: 327 --PPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLN-PPPAPP 380
Score = 70.1 bits (170), Expect = 1e-11
Identities = 53/167 (31%), Positives = 71/167 (42%), Gaps = 34/167 (20%)
Query: 191 PGVSTVPNTTQASTPPQTQTPQPN--PPPVQATPHPFPAVTPDLIVQTPVMT--VVPPQP 246
P + NT++A +T P+PN PP P P P + P L +P+ T V PP P
Sbjct: 147 PASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGP 206
Query: 247 LQ------TPPPVP---PQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTP 297
L PPVP P P PPP P P P+ PP + + VK +
Sbjct: 207 LTKGNLPVVAPPVPCAPPPPPPPPPPTPPPL---PPASVLSDKAVKPQ------------ 251
Query: 298 TTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAP 344
+ P+H PP PP P G + P P + D+Q+ PAP
Sbjct: 252 --LAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQ----DAQEPPAP 292
Score = 51.2 bits (121), Expect = 7e-06
Identities = 63/266 (23%), Positives = 91/266 (34%), Gaps = 37/266 (13%)
Query: 950 VQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQP----QPPPQQQHQPPPRPVHLQPMQFS 1005
V PPPPLPPPP P PPPPPP P ++ P R L +Q
Sbjct: 3 VPPPPPPPLPPPPPP------LGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQG 56
Query: 1006 THIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSP 1065
T +++ + P + +K + S P + G L P
Sbjct: 57 TRLRKVTQINDRSAPQ---------IESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFP 107
Query: 1066 LMIHSPQMSQFQSLTHQSPPQQNVQPK-KQELRAASVVQPQPLVVVKEEKIH-----SPI 1119
++ + Q T Q P + P+ + + ++ P + + H +P
Sbjct: 108 VLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPP 167
Query: 1120 IRSEPFSPSLRPEPPKHP--------ESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPP 1171
+ P P P PP P IK P+ P P K PV+ PP APP
Sbjct: 168 RPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKG---NLPVVAPPVPCAPP 224
Query: 1172 PGAPDKDKQKQEPKTPVAPKKDLKIK 1197
P P P P + D +K
Sbjct: 225 P-PPPPPPPTPPPLPPASVLSDKAVK 249
Score = 50.1 bits (118), Expect = 1e-05
Identities = 79/348 (22%), Positives = 111/348 (31%), Gaps = 55/348 (15%)
Query: 880 LPPKPARPPAVSPALTQTPLLPQPPMAQPP------QVLLEDEEPPAPPLTSMQMQLYLQ 933
+P P PP + P P PP + PP + D + + L +Q L+
Sbjct: 1 MPVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLR 60
Query: 934 QLQKVQP-PTPLLPSVK-------------VQSQPP----------PPLPPPPHPSVQQQ 969
++ ++ P + S K S PP P L P V
Sbjct: 61 KVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGG 120
Query: 970 LQQQPPPPPPPQPQPPPQQQHQP--PPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQ 1027
Q P P P+ P + P PP L + + PP+ P PPP
Sbjct: 121 KTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPP 180
Query: 1028 PPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQ 1087
PPPP P +P P + G+L P+ P PP
Sbjct: 181 PPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPP------------PPPP 228
Query: 1088 NVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKA----P 1143
P L ASV+ + V + +H P P P L PP +KA P
Sbjct: 229 PPPPTPPPLPPASVLSDK-AVKPQLAPLHLP-----PIPPPLPLLPPCGYPGLKAEPASP 282
Query: 1144 VHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPK 1191
Q P P + P + P P P + + P P+ PK
Sbjct: 283 AQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETP-PPLPPK 329
Score = 43.1 bits (100), Expect = 0.002
Identities = 52/220 (23%), Positives = 73/220 (33%), Gaps = 62/220 (28%)
Query: 191 PGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFP--------AVTPDLIVQ-----TP 237
PG T N + PP P P PPP TP P P AV P L P
Sbjct: 204 PGPLTKGNLPVVA-PPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPP 262
Query: 238 VMTVVPP--------------QPLQTPP------------------PVPPQP-------Q 258
+ ++PP Q Q PP P PP P
Sbjct: 263 PLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSET 322
Query: 259 PPPAPAPQPVQSHPP------IIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPE 312
PPP P P PP + A P P ++ +++K ++ PP+ P
Sbjct: 323 PPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPAR 382
Query: 313 PKTTKLGQRRESS---RPVKPPKKDVPDSQQHPAPEKSSK 349
TT+L + + + P + P + + H + SK
Sbjct: 383 SPTTELSSKSQQATAWTPTQQPGGQLRNGSLHIIDDFESK 422
Score = 36.6 bits (83), Expect = 0.17
Identities = 21/55 (38%), Positives = 22/55 (40%), Gaps = 13/55 (23%)
Query: 239 MTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKAD 293
M V PP P PPP PP PPP P P PV T R+AD
Sbjct: 1 MPVPPPPPPPLPPPPPPLGAPPPPPPSAP-------------PVSTDTSSLRRAD 42
Score = 32.7 bits (73), Expect = 2.4
Identities = 27/88 (30%), Positives = 40/88 (45%), Gaps = 8/88 (9%)
Query: 457 MPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQE 516
MP P P P PPP + APP S+ S+D+ S + R+ LA++Q+
Sbjct: 1 MPVPPPPP-----PPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQ 55
Query: 517 --QLKAVHEQLAALSQPQQNKPKKKEKD 542
+L+ V Q+ S PQ K K+
Sbjct: 56 GTRLRKV-TQINDRSAPQIESSKGTNKE 82
>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
sapiens]
Length = 309
Score = 110 bits (275), Expect = 9e-24
Identities = 98/298 (32%), Positives = 119/298 (39%), Gaps = 56/298 (18%)
Query: 754 PQQPPPPPQQPPPPPPP--QQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQ 811
PQ+ PPPP +P PP Q Q PPP P P P PPP
Sbjct: 47 PQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPP------------ 94
Query: 812 LPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPS 871
PG P G QP Q + PP P PE P NQ PP P
Sbjct: 95 RPGK---PEG---QPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQ--GPPPRPGKPEGPPP 146
Query: 872 RPSNRAAALPPKPARPPAVSP----ALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQ 927
+ N++ PP+P +P P P P P PPQ + + PP P
Sbjct: 147 QGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRP----- 201
Query: 928 MQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPH-PSVQQQLQQQPPPPPPPQPQ-PP 985
K + P P + QSQ PPP P P P Q + Q PPP P +PQ PP
Sbjct: 202 --------GKPEGPPPQGGN---QSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPP 250
Query: 986 PQQQHQPPPRPVHLQPMQFSTHIQQPPPPQG--QQPPHPPPGQ---QPPPPQPAKPQQ 1038
PQ+ ++P P +P Q PPPP G QQP PP G+ PPPPQ +P +
Sbjct: 251 PQEGNKPQRPPPPGRP-------QGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHR 301
Score = 102 bits (253), Expect = 3e-21
Identities = 102/340 (30%), Positives = 122/340 (35%), Gaps = 66/340 (19%)
Query: 709 SSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPP--------P 760
S+ S +ED E +P S G P E ++ + Q P P+ PP P
Sbjct: 15 SAQSLNEDVSQEESP-SVISGKP--EGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGP 71
Query: 761 PQQPPPP--PPPQQQQQPPPPPPPPSMPQQAAPA---MKSSPPPFIATQVPVLEPQLPGS 815
P +P P PPPQ Q PPP P P+ P PPP PG
Sbjct: 72 PPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPP------------RPGK 119
Query: 816 VFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSN 875
P P Q + PP P PE P NQ PP P + N
Sbjct: 120 PEGP------PPQGGNQSQGPPPRPGKPEGPPPQGGNQSQ--GPPPRPGKPEGPPPQGGN 171
Query: 876 RAAALPPKPARPPAVSP----ALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLY 931
++ PP P +P P P P P PPQ + + PP P
Sbjct: 172 QSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRP--------- 222
Query: 932 LQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPP---QQ 988
K + P P K Q PP P P P + Q+PPPP PQ PPP Q
Sbjct: 223 ----GKPEGP-PSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQ 277
Query: 989 QHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQP 1028
Q PPP P PPPPQG +P PP GQ P
Sbjct: 278 QPLPPPAGKPQGP---------PPPPQGGRPHRPPQGQPP 308
Score = 94.7 bits (234), Expect = 5e-19
Identities = 104/369 (28%), Positives = 132/369 (35%), Gaps = 99/369 (26%)
Query: 832 QPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQ-QPSRPSNRAAALPPKPARPPAV 890
Q E P + PE P NQ PP P+ +P + N++ PP+P +P
Sbjct: 25 QEESPSVISGKPEGRRPQGGNQPQRTPPPP---GKPEGRPPQGGNQSQGPPPRPGKPEGP 81
Query: 891 SPA----LTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLP 946
P P P P QPPQ + + PP P K + P P
Sbjct: 82 PPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRP-------------GKPEGPPPQGG 128
Query: 947 SVKVQSQPPPPLPPPPH-PSVQQQLQQQPPPPPPPQPQ-PPPQ---QQHQPPPRPVHLQ- 1000
+ QSQ PPP P P P Q Q Q PPP P +P+ PPPQ Q PPP P +
Sbjct: 129 N---QSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEG 185
Query: 1001 -PMQFSTHIQQPPPPQGQQPPHPPPG---QQPPPPQPAKPQQVIQHHHSPRHHKSDPYST 1056
P Q Q PPP G+ PP G Q PPP+P KP+ P
Sbjct: 186 PPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPE-------------GPPSQG 232
Query: 1057 GHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIH 1116
G+ + P P P Q PPQ+ +P+
Sbjct: 233 GNKPQGPPP----HPGKPQ------GPPPQEGNKPQ------------------------ 258
Query: 1117 SPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPD 1176
RP PP P+ P PQ+P P G+P PP P G P
Sbjct: 259 -------------RPPPPGRPQGPPPPGGNPQQP--LPPPAGKPQGPPP---PPQGGRPH 300
Query: 1177 KDKQKQEPK 1185
+ Q Q P+
Sbjct: 301 RPPQGQPPQ 309
Score = 80.5 bits (197), Expect = 1e-14
Identities = 79/259 (30%), Positives = 98/259 (37%), Gaps = 38/259 (14%)
Query: 951 QSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQ-PPPQ---QQHQPPPRP--VHLQPMQF 1004
Q PPPP P P Q Q Q PPP P +P+ PPPQ Q PPPRP QP Q
Sbjct: 48 QRTPPPPGKPEGRPP-QGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQG 106
Query: 1005 STHIQQPPPPQGQQPPHPPPG---QQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLRE 1061
Q PPP G+ PP G Q PPP+P KP+ P G+ +
Sbjct: 107 GNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPE-------------GPPPQGGNQSQ 153
Query: 1062 APSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIR 1121
P P Q PP +P+ + + Q P K E P
Sbjct: 154 GPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEG-PPPQGG 212
Query: 1122 SEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPE-----QNAPPPGAPD 1176
++ P RP P+ P P +P+ P G+P PP+ Q PPPG P
Sbjct: 213 NQSQGPPPRPGKPEGP-----PSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQ 267
Query: 1177 ----KDKQKQEPKTPVAPK 1191
Q+P P A K
Sbjct: 268 GPPPPGGNPQQPLPPPAGK 286
Score = 73.6 bits (179), Expect = 1e-12
Identities = 76/265 (28%), Positives = 90/265 (33%), Gaps = 65/265 (24%)
Query: 731 PGREQKKHHHHHHQQMQQAPAPVPQQPPPP----PQQPPPP-------PPPQ---QQQQP 776
PG+ + + +Q P P + PPP Q PPP PPPQ Q Q P
Sbjct: 96 PGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGP 155
Query: 777 PPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELP 836
PP P P P PPP PG P P Q + P
Sbjct: 156 PPRPGKPEGPPPQGGNQSQGPPPH------------PGKPEGP------PPQGGNQSQGP 197
Query: 837 PHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQ 896
P P PE P NQ PP PS+ N+ PP P +P P
Sbjct: 198 PPRPGKPEGPPPQGGNQSQ--GPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGN 255
Query: 897 TPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPP 956
P P PP +P + P PP + Q L PP P+ K Q PPP
Sbjct: 256 KPQRPPPP-GRP--------QGPPPPGGNPQQPL---------PP----PAGKPQGPPPP 293
Query: 957 PLPPPPHPSVQQQLQQQPPPPPPPQ 981
P PH +PP PPQ
Sbjct: 294 PQGGRPH---------RPPQGQPPQ 309
Score = 50.1 bits (118), Expect = 1e-05
Identities = 27/68 (39%), Positives = 32/68 (47%), Gaps = 9/68 (13%)
Query: 730 HPGREQKKHHHHHHQQMQQAPAPVPQQPPPP---PQQPPPPPPPQQQQQPPPPP------ 780
HPG+ Q ++ + P PQ PPPP PQQP PPP + Q PPPP
Sbjct: 242 HPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHR 301
Query: 781 PPPSMPQQ 788
PP P Q
Sbjct: 302 PPQGQPPQ 309
Score = 41.6 bits (96), Expect = 0.005
Identities = 59/241 (24%), Positives = 87/241 (36%), Gaps = 47/241 (19%)
Query: 146 IVLMAEALEKLF-LQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQAST 204
++L++ AL L Q +NE ++E ++ G+ GR+ G +P + P
Sbjct: 3 LILLSVALLALSSAQSLNEDVSQEESPSVIS--GKPEGRRPQGGNQPQRTPPPPGKPEGR 60
Query: 205 PPQ----TQTPQPNP-----PPVQAT-----PHPFPAVTPDLIVQTPVMTVVPP------ 244
PPQ +Q P P P PP Q P P P Q + PP
Sbjct: 61 PPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPPRPGKP 120
Query: 245 --------QPLQTPPPVPPQPQPPP--------APAPQPVQSHPPIIAATPQPVKTKKGV 288
Q PPP P +P+ PP P P+P + P PQ +G
Sbjct: 121 EGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGP----PPQGGNQSQGP 176
Query: 289 ---KRKADTTTPTTIDPIHEPPSLPPEPK-TTKLGQRRESSRPVKPPKKDVPDSQQHPAP 344
K + P + PP P +P+ G + P +P K + P SQ P
Sbjct: 177 PPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKP 236
Query: 345 E 345
+
Sbjct: 237 Q 237
Score = 38.9 bits (89), Expect = 0.034
Identities = 38/155 (24%), Positives = 52/155 (33%), Gaps = 22/155 (14%)
Query: 205 PPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQP-------LQTPPPVPPQP 257
PPQ PPP P P + P P P Q PPP P +P
Sbjct: 124 PPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKP 183
Query: 258 QPPP--------APAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSL 309
+ PP P P+P + P PQ +G + ++P
Sbjct: 184 EGPPPQGGNQSQGPPPRPGKPEGP----PPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGP 239
Query: 310 PPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAP 344
PP P + +E ++P +PP P Q P P
Sbjct: 240 PPHPGKPQGPPPQEGNKPQRPPP---PGRPQGPPP 271
Score = 38.1 bits (87), Expect = 0.058
Identities = 28/86 (32%), Positives = 32/86 (37%), Gaps = 3/86 (3%)
Query: 178 GRGRGRKETGTAKP-GVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQT 236
G+ G G KP G P Q P + PQ PPP + P P P +
Sbjct: 223 GKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPP 282
Query: 237 PV--MTVVPPQPLQTPPPVPPQPQPP 260
P PP P P PPQ QPP
Sbjct: 283 PAGKPQGPPPPPQGGRPHRPPQGQPP 308
Score = 37.0 bits (84), Expect = 0.13
Identities = 26/79 (32%), Positives = 29/79 (36%), Gaps = 18/79 (22%)
Query: 197 PNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTP--PPVP 254
P + PP +P PP PHP P PPQ P PP P
Sbjct: 220 PRPGKPEGPPSQGGNKPQGPP----PHPGKPQGP------------PPQEGNKPQRPPPP 263
Query: 255 PQPQPPPAPAPQPVQSHPP 273
+PQ PP P P Q PP
Sbjct: 264 GRPQGPPPPGGNPQQPLPP 282
Score = 36.6 bits (83), Expect = 0.17
Identities = 38/152 (25%), Positives = 47/152 (30%), Gaps = 29/152 (19%)
Query: 205 PPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQP-------LQTPPPVPPQP 257
PPQ PPP P P + P P P Q PPP P +P
Sbjct: 166 PPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKP 225
Query: 258 QPPPA----------PAPQPVQSHPPIIAATPQ---PVKTKKGVKRKADTTTPTTIDPIH 304
+ PP+ P P Q PP PQ P +G P
Sbjct: 226 EGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAG 285
Query: 305 EPPSLPPEPKTTKLGQRRESSRPVKPPKKDVP 336
+P PP P + RP +PP+ P
Sbjct: 286 KPQGPPPPP---------QGGRPHRPPQGQPP 308
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 107 bits (266), Expect = 1e-22
Identities = 151/585 (25%), Positives = 196/585 (33%), Gaps = 115/585 (19%)
Query: 708 ESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPP--PPPQQPP 765
E+S S T A S REQ QQM Q QP PPP PP
Sbjct: 29 EASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPP 88
Query: 766 PPPPP---QQQQQPPPPP-PPPSMP-----------QQAAPAMKSSPPPFIATQV---PV 807
PP P QPPPPP PPP P Q + PP + ++ P
Sbjct: 89 PPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPE 148
Query: 808 LEPQLPGSVFDPIGHFTQPILHLP--------QPELPPHLPQPPEHSTPPHLNQHAVVSP 859
P PGS P + P P QP LPP P P + +PP +Q +
Sbjct: 149 SPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQ--SPP--SQSYLAPT 204
Query: 860 PALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPP-------QVL 912
P+ ++ S S+ + LP A P S +++ LL PP + PP Q
Sbjct: 205 PSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEP 264
Query: 913 LED-------------EEPPAPPLTSMQMQLY--------LQQLQKVQPPTPLLPSVKVQ 951
LE EP +T + Q Y LQQ KV P V +
Sbjct: 265 LESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAK 324
Query: 952 SQPPPPLPPPPHPSVQQ----QLQQQPPPPPP----PQPQPPPQQQHQPPPRPVHLQPMQ 1003
P P P+ Q ++PP PPP P P PP + Q + P L+ +Q
Sbjct: 325 DTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQLQ 384
Query: 1004 -FSTHIQQPPPP------QGQQPPHPPPGQ---------QPPPP-QPAKPQQVIQHHHSP 1046
+ H QQ QG H Q QPPP Q ++H+
Sbjct: 385 AAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQ 444
Query: 1047 RHHKSDPYSTGHLREAPSPLMIHS-PQMSQFQSLT--------HQSPPQQNVQPKKQELR 1097
+ Y +HS P Q Q H Q +Q K +
Sbjct: 445 QQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQ 504
Query: 1098 ------AASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPE 1151
++ P P V P + P P++ PP P S+ PV P P
Sbjct: 505 NMKNQYMGNMSMPPPFV---------PYSQMPPPLPTM--PPPVLPPSLPPPVMPPALPA 553
Query: 1152 MKPVDVGRPVIRPPE--QNAPPPGAPDKDKQKQEPKTPVAPKKDL 1194
P P + PP + PPPG P P PV P L
Sbjct: 554 TVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPP--PVLPPPSL 596
Score = 103 bits (257), Expect = 1e-21
Identities = 110/432 (25%), Positives = 157/432 (36%), Gaps = 111/432 (25%)
Query: 838 HLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVS---PAL 894
H P PP PP PP + ALP+ P ++ P P+ +S L
Sbjct: 13 HYPPPP---VPP---------PPPV--ALPEASPGPGYSSSTTPAAPSSSGFMSFREQHL 58
Query: 895 TQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLP--SVKVQS 952
Q L Q Q Q +L+ P PPL PP P++P
Sbjct: 59 AQLQQLQQMHQKQ-MQCVLQPHHLPPPPL----------------PPPPVMPGGGYGDWQ 101
Query: 953 QPPPPLPPPPHPSVQQQLQQQ------------PP-------------PPPPPQPQPPPQ 987
PPPP+PPPP P++ Q QQQ PP PP PP PP
Sbjct: 102 PPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPS 161
Query: 988 QQHQPPPRPVHLQPMQFSTHIQQP-PPPQGQQPPHPPPGQQPPPPQP------AKPQQVI 1040
Q + PPP+P P + QP PP P PP Q P P + Q +
Sbjct: 162 QSYMPPPQP---PPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYL 218
Query: 1041 QHHHS--PRHHKSDPY-STGHLRE---APSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQ 1094
H S P S S GH + AP P P T Q P ++ K
Sbjct: 219 SHSQSYLPSSQASPSRPSQGHSKSQLLAPPP-----PSAPPGNKTTVQQEPLESGAKNKS 273
Query: 1095 ELRAASVVQPQPLVVVKEE-----------------KIHSPIIRSEPFSPSLRPEPPKHP 1137
+ + +P P + +E K+H P + P PEP K
Sbjct: 274 TEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEE 333
Query: 1138 ESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIK 1197
++ A +P+ P + P + PP + PPP P++ + + P++D ++K
Sbjct: 334 VTVPATSQVPESPSSE-----EPPLPPPNEEVPPPLPPEEPQSED-------PEEDARLK 381
Query: 1198 NMGSWASLVQKH 1209
+ + A+ Q+H
Sbjct: 382 QLQAAAAHWQQH 393
Score = 89.4 bits (220), Expect = 2e-17
Identities = 209/992 (21%), Positives = 327/992 (32%), Gaps = 194/992 (19%)
Query: 471 PAVPPPTKVVAPPSSSDSS-SDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALS 529
P VPPP V P +S S S++ + S+ R Q LA+LQ+ + +Q+ +
Sbjct: 17 PPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVL 76
Query: 530 QPQQN-------------------KPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPP 570
QP +P ++++++ + ++ PP
Sbjct: 77 QPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPP 136
Query: 571 KKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKL 630
S + P P S PP+ + P Y P
Sbjct: 137 GLVPMELESPP---ESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQ 193
Query: 631 GRVVHIIQSREPSLKNSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQA--EKVDV 688
+ PS +S+ S L + Y+ S +P K +
Sbjct: 194 SPPSQSYLAPTPSYSSSSSSS---------QSYLSHSQSYLPSSQASPSRPSQGHSKSQL 244
Query: 689 IAGS--SKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQ-Q 745
+A S G ++ + ES + + + + AP+ +EQ+++ + H
Sbjct: 245 LAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLS 304
Query: 746 MQQ------------------APAPV--------------------PQQPPPPPQQPPPP 767
+QQ P PV P PPP + PPP
Sbjct: 305 LQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPL 364
Query: 768 PPPQQQQQPPPPPPPPSMPQQAAPAMKS-------------------------------S 796
PP + Q + P Q AA +
Sbjct: 365 PPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQ 424
Query: 797 PPPFIATQ---VPVLEPQLPGSVFDPIGHFTQPILHLPQPELP--PHLPQPPEH------ 845
PPP I T + + ++ F + + L + +L PH Q E+
Sbjct: 425 PPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKT 484
Query: 846 ------STPPHLNQHAVVSPPALHNALPQQPSRP------SNRAAALP--PKPARPPAVS 891
+T +L Q V S + N S P S LP P P PP++
Sbjct: 485 WQGHMKATQSYL-QEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLP 543
Query: 892 PALTQTPLLPQ--PPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVK 949
P + P LP PP PP V+ PP+ P TS+ L PP P+LP
Sbjct: 544 PPV-MPPALPATVPPPGMPPPVM-----PPSLP-TSVPPPGMPPSLSSAGPP-PVLPPPS 595
Query: 950 VQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQ 1009
+ S PPP+ PPP S PPP P PP PP P +
Sbjct: 596 LSSAGPPPVLPPPSLS--------STAPPPVMPLPPLSSATPPPGIP--------PPGVP 639
Query: 1010 QPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIH 1069
Q PPQ P PP P KP+ + +P S P +T H PL
Sbjct: 640 QGIPPQLTAAPVPPASSSQSSQVPEKPRPALL--PTPVSFGSAPPTTYH-----PPLQSA 692
Query: 1070 SP--QMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSP 1127
P Q++ L+ + P + Q L +S QP+ VK+ + S + +P
Sbjct: 693 GPSEQVNSKAPLSKSALPYSSFS-SDQGLGESSAAPSQPITAVKDMPVRSGGLLPDPPRS 751
Query: 1128 SLRPEP-------PKHPESIKAPVHLPQRPEMKPVDVGRP-VIRPPEQNAPPPGAPDKDK 1179
S P P+ E + + P RP+ + RP RP + P G K K
Sbjct: 752 SYLESPRGPRFDGPRRFEDLGSRCEGP-RPKGPRFEGNRPDGPRPRYEGHPAEGT--KSK 808
Query: 1180 QKQEPKTP-----VAPKKDLKIKNMG-SW----ASLVQKHPTTPSSTAKSSSDSFEQFRR 1229
P+ P + P L + G W + Q+H P S A+ S + E
Sbjct: 809 WGMIPRGPASQFYITPSTSLSPRQSGPQWKGPKPAFGQQHQQQPKSQAEPLSGNKEPLAD 868
Query: 1230 AAREKEEREK----ALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQ 1285
+ +++ K A A+ + + + + S+++ E + E + Q
Sbjct: 869 TSSNQQKNFKMQSAAFSIAADVKDVKAAQSNENLSDSQQEPPKSEVSEGPVEPSNWDQNV 928
Query: 1286 QQQQRQEQQQQQQQQAAAVAAAATPQAQSSQP 1317
Q + Q + Q Q +A P AQS+ P
Sbjct: 929 QSMETQIDKAQAVTQPVPLANKPVP-AQSTFP 959
Score = 88.6 bits (218), Expect = 4e-17
Identities = 109/450 (24%), Positives = 148/450 (32%), Gaps = 139/450 (30%)
Query: 759 PPPQQPPPPPPP-------------------------------------QQQQQ------ 775
PPP P PPPPP QQ QQ
Sbjct: 15 PPP--PVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQM 72
Query: 776 ----------PPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQ 825
PPP PPPP MP + PP P+ P P + +
Sbjct: 73 QCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPP-------PMPPPPGPALSYQKQQQYKH 125
Query: 826 PILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPA 885
+LH Q + PP L P E +PP SPP +P P +++ PP+P
Sbjct: 126 QMLH-HQRDGPPGL-VPMELESPPE-------SPP-----VPPGSYMPPSQSYMPPPQP- 170
Query: 886 RPPAVSPALTQTPLLP--QPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTP 943
PP+ P + P LP QP +Q P P+ +S Q YL Q P +
Sbjct: 171 -PPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQ 229
Query: 944 LLPSVKVQSQ-------PPPPLPPPPHPSVQQQ------------LQQQPPPPPPPQPQP 984
PS Q PPPP PP + + QQ QQQ P P P
Sbjct: 230 ASPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMT 289
Query: 985 PPQQQ-----------------HQP-----------PPRPVHLQPMQFSTHIQQPPPPQG 1016
P +QQ H P P PV + + Q P P
Sbjct: 290 PQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVK-EEVTVPATSQVPESPSS 348
Query: 1017 QQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQF 1076
++PP PPP ++ PPP P + Q DP L++ +
Sbjct: 349 EEPPLPPPNEEVPPPLPPEEPQ-----------SEDPEEDARLKQLQAAAAHWQQHQQHR 397
Query: 1077 QSLTHQSPPQQNVQPKKQELRAASVVQPQP 1106
+Q Q++ Q ++ + ++QP P
Sbjct: 398 VGFQYQGIMQKHTQLQQILQQYQQIIQPPP 427
Score = 87.4 bits (215), Expect = 8e-17
Identities = 165/776 (21%), Positives = 274/776 (35%), Gaps = 115/776 (14%)
Query: 458 PDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERA------QRL 511
P P + A PPP+ APP + + +S + +E+++A +
Sbjct: 232 PSRPSQGHSKSQLLAPPPPS---APPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTM 288
Query: 512 AELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPK 571
++Q + L +L Q + +K K KEEV S+ E P
Sbjct: 289 TPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSS 348
Query: 572 KTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPM-------SYEEKRQLSLDINK 624
+ N V P P+ + P + + EE+ + K + ++ ++
Sbjct: 349 EEPPLPPPNEEV----PPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQG 404
Query: 625 LPGEKLGRVVHIIQSREPSLK-NSNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQA 683
+ +K ++ I+Q + ++ + + +D + ++ +++ ++ +
Sbjct: 405 IM-QKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWE 463
Query: 684 EKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHH 743
E++ +++ + ++ S E + ++ K + G +
Sbjct: 464 EQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPY 523
Query: 744 QQMQQAPAPVPQQPPP--PPQQPPP-PPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPF 800
QM P P+P PPP PP PPP PP PPP PPP MP P++ +S PP
Sbjct: 524 SQM---PPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMP----PSLPTSVPP- 575
Query: 801 IATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPEL-----PPHLPQPPEHSTPPHLNQHA 855
P + P L + P+ LP P L PP LP P ST P
Sbjct: 576 -----PGMPPSLSSAGPPPV---------LPPPSLSSAGPPPVLPPPSLSSTAP----PP 617
Query: 856 VVSPPALHNALPQQPSRPSNRAAALPPKPAR---PPAVSPALTQTPLLPQPPMAQPPQVL 912
V+ P L +A P P +PP+ PPA S +Q P P+P + P
Sbjct: 618 VMPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSF 677
Query: 913 LEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSV--QQQL 970
APP T Y LQ PS +V S+ P P+ S Q L
Sbjct: 678 -----GSAPPTT------YHPPLQSAG------PSEQVNSKAPLSKSALPYSSFSSDQGL 720
Query: 971 QQQPPPPPPP--------------QPQPPPQQQHQPPPRPVHLQPMQF---STHIQQPPP 1013
+ P P P PP + P P P +F + + P P
Sbjct: 721 GESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRP 780
Query: 1014 P----QGQQPPHPPPGQQPPPPQPAK------PQQVIQHHHSPRHHKSDPYSTGHLREAP 1063
+G +P P P + P + K P+ + P +G + P
Sbjct: 781 KGPRFEGNRPDGPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKGP 840
Query: 1064 SPLMIHSPQM---SQFQSLTHQSPPQQNV---QPKKQELRAASVVQPQPLVVVKEEKIHS 1117
P Q SQ + L+ P + Q K ++++A+ + VK + +
Sbjct: 841 KPAFGQQHQQQPKSQAEPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNE 900
Query: 1118 PIIRSEPFSP-SLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPP 1172
+ S+ P S E P P + V + K V +PV P N P P
Sbjct: 901 NLSDSQQEPPKSEVSEGPVEPSNWDQNVQSMETQIDKAQAVTQPV---PLANKPVP 953
Score = 86.3 bits (212), Expect = 2e-16
Identities = 198/894 (22%), Positives = 300/894 (33%), Gaps = 183/894 (20%)
Query: 467 AVSSPAVPPPTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLA 526
A SP+ PP++ P+ S SSS SSS S S S +Q Q H +
Sbjct: 187 AQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQ---GHSKSQ 243
Query: 527 ALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKK 586
L+ P + P K+ ++ P + KN S+ +
Sbjct: 244 LLAPPPPSAPP----------------------GNKTTVQQEPLESGAKNKSTEQQQAAP 281
Query: 587 EPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKN 646
EP P S P + + + +S +++ ++ L PG K G P +
Sbjct: 282 EPDP--STMTPQEQQQYWYRQHLLSLQQRTKVHL-----PGHKKG----------PVVAK 324
Query: 647 SNPDEIEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESS 706
P+ ++ E P+T + E P +E+ + + ++ E E
Sbjct: 325 DTPEPVKE--EVTVPATSQVPE-----------SPSSEEPPLPPPNEEVPPPLPPE-EPQ 370
Query: 707 SESSSSDSEDSETEMAPK--SKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQP 764
SE D+ + + A + + H Q + H Q+QQ Q PPP
Sbjct: 371 SEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQ 430
Query: 765 PPPPPPQ------QQQQ-----------------PPPPPPPPSMPQQAAPAMKSSPPPFI 801
Q QQQQ P Q+ K+
Sbjct: 431 TMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMK 490
Query: 802 ATQVPVLEP--QLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSP 859
ATQ + E +G+ + P +P ++PP LP P PP L P
Sbjct: 491 ATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSL------PP 544
Query: 860 PALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPP 919
P + ALP A +PP P PP V P P P + PP P
Sbjct: 545 PVMPPALP----------ATVPP-PGMPPPVMP--------PSLPTSVPP--------PG 577
Query: 920 APPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPP 979
PP L PP P+LP + S PPP+ PPP S PPP
Sbjct: 578 MPP-----------SLSSAGPP-PVLPPPSLSSAGPPPVLPPPSLS--------STAPPP 617
Query: 980 PQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQV 1039
P PP PP P + Q PPQ P PP P KP+
Sbjct: 618 VMPLPPLSSATPPPGIP--------PPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPA 669
Query: 1040 IQHHHSPRHHKSDPYSTGHLREAPSPLMIHSP--QMSQFQSLTHQSPPQQNVQPKKQELR 1097
+ +P S P +T H PL P Q++ L+ + P + Q L
Sbjct: 670 LLP--TPVSFGSAPPTTYH-----PPLQSAGPSEQVNSKAPLSKSALPYSSFS-SDQGLG 721
Query: 1098 AASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEP-------PKHPESIKAPVHLPQRP 1150
+S QP+ VK+ + S + +P S P P+ E + + P RP
Sbjct: 722 ESSAAPSQPITAVKDMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGP-RP 780
Query: 1151 EMKPVDVGRPV-IRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGSWASLVQKH 1209
+ + RP RP + P G K K P+ P AS
Sbjct: 781 KGPRFEGNRPDGPRPRYEGHPAEGT--KSKWGMIPRGP---------------ASQFYIT 823
Query: 1210 PTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDAL 1269
P+T S + + S ++ + A ++ +++ K+QAE KE L +++
Sbjct: 824 PST-SLSPRQSGPQWKGPKPAFGQQHQQQP--KSQAEPLSGNKEPLADTSSNQQKNFKMQ 880
Query: 1270 EQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQ 1323
A + + + Q + QQ+ ++ P QSM Q
Sbjct: 881 SAAFSIAADVKDVKAAQSNENLSDSQQEPPKSEVSEGPVEPSNWDQNVQSMETQ 934
Score = 57.8 bits (138), Expect = 7e-08
Identities = 66/250 (26%), Positives = 91/250 (36%), Gaps = 82/250 (32%)
Query: 858 SPPALHNALPQQPSRPSNRAAAL----PPKPARPPAVSPALTQTPLLPQPPMAQPPQVLL 913
S P + + LP Q SR N ++ PP RPP PPM +PP ++
Sbjct: 1481 SEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPP--------------PPMGKPPGSIV 1526
Query: 914 EDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQ 973
P APP S + +PP P+ PPP PPPP
Sbjct: 1527 R---PSAPPARS--------SVPVTRPPVPI----------PPPPPPPP----------L 1555
Query: 974 PPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQ-------------------PPPP 1014
PPPPP +PQ +Q + + + T+ +Q PPPP
Sbjct: 1556 PPPPPVIKPQTSAVEQERWDEDSFY---GLWDTNDEQGLNSEFKSETAAIPSAPVLPPPP 1612
Query: 1015 QGQQ--PPHPPPGQQPPPPQPAKPQQVIQHHH----SPRHHKSDPYSTGHLREAPSPLMI 1068
PP P P PP +P QQ + + H S + PY + P PL
Sbjct: 1613 VHSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGE-RITLRPDPL-- 1669
Query: 1069 HSPQMSQFQS 1078
P+ S F++
Sbjct: 1670 --PERSTFET 1677
Score = 57.4 bits (137), Expect = 9e-08
Identities = 91/374 (24%), Positives = 135/374 (36%), Gaps = 56/374 (14%)
Query: 23 TSQMSTTQAQAQPQ--PANAASTNPPPPETSNPNKPKRQTNQLQYLLRVV-LKTLWKHQF 79
TSQ+ + + +P P N P PPE P+ Q + +H+
Sbjct: 339 TSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRV 398
Query: 80 AWPFQ---QPVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNC 136
+ +Q Q ++ L Y +II+ P + T+ ++ +Y Q+ Q +
Sbjct: 399 GFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWERE 458
Query: 137 Y------IYNKPGDDIVLMAEALEKLFL--QKINELPTEETEIMIVQAKGRGRGRKETGT 188
+ +++ P D + E K + K + +E K + G
Sbjct: 459 FQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMSMPP 518
Query: 189 AKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVM-----TVVP 243
S +P PP P PPPV P PA P + PVM T VP
Sbjct: 519 PFVPYSQMPPPLPTMPPPVL--PPSLPPPVM--PPALPATVPPPGMPPPVMPPSLPTSVP 574
Query: 244 PQPLQT------PPPVPPQPQ----------PPPA---PAPQPVQSHPPIIAATPQPVKT 284
P + PPPV P P PPP+ AP PV PP+ +ATP P
Sbjct: 575 PPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIP 634
Query: 285 KKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKK----DVPDSQQ 340
GV P I P +PP +++ Q E RP P P +
Sbjct: 635 PPGV--------PQGIPPQLTAAPVPP-ASSSQSSQVPEKPRPALLPTPVSFGSAPPTTY 685
Query: 341 HPAPEKSSKVSEQL 354
HP P +S+ SEQ+
Sbjct: 686 HP-PLQSAGPSEQV 698
Score = 50.4 bits (119), Expect = 1e-05
Identities = 65/257 (25%), Positives = 95/257 (36%), Gaps = 55/257 (21%)
Query: 678 KRKPQAEKVDVIAGSSKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKK 737
+ P AE + SS+M G +S + E+ K+ ++ REQK+
Sbjct: 1412 RHSPMAEHMPSSHHSSEMMGSDASLDSDQGLGGVMVLSQRQHEIILKAAQELKMLREQKE 1471
Query: 738 HHHHHHQQMQQAPAPVPQQPPPPPQQ---------PPPPPPPQQQQQPPP-PPPPPSMPQ 787
Q+M+ + PPQ+ P PPP + PPP PP S+ +
Sbjct: 1472 QL----QKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVR 1527
Query: 788 QAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHST 847
+AP +SS VPV P +P +P P PP LP PP
Sbjct: 1528 PSAPPARSS--------VPVTRPPVP----------------IPPPPPPPPLPPPPPVIK 1563
Query: 848 PPHLNQHAVVSPP--------ALHNALPQQ--PSRPSNRAAALPPKPARPPAVSPALTQT 897
P Q + V L + +Q S + AA+P P PP +
Sbjct: 1564 P----QTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPP 1619
Query: 898 P---LLPQPPMAQPPQV 911
P + PPM++PP V
Sbjct: 1620 PGPVPMGMPPMSKPPPV 1636
Score = 48.5 bits (114), Expect = 4e-05
Identities = 50/172 (29%), Positives = 68/172 (39%), Gaps = 29/172 (16%)
Query: 832 QPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSN--RAAALPPKPA---- 885
+P++ HLP P E ++ + PP + P P + R +A P + +
Sbjct: 1482 EPQMADHLP-PQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVT 1540
Query: 886 RPPAVSPALTQTPLLPQPPMAQPPQV-LLEDEEPPAPPLTSMQMQLYLQQL-QKVQPPTP 943
RPP P P LP PP PQ +E E + Q L + + T
Sbjct: 1541 RPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETA 1600
Query: 944 LLPSVKVQSQPPPPLPPPP-HPSVQQQLQQQPPPPP-----PPQPQPPPQQQ 989
+PS P LPPPP H S+ PPP P PP +PPP QQ
Sbjct: 1601 AIPSA-------PVLPPPPVHSSI-------PPPGPVPMGMPPMSKPPPVQQ 1638
Score = 47.8 bits (112), Expect = 7e-05
Identities = 36/108 (33%), Positives = 47/108 (43%), Gaps = 6/108 (5%)
Query: 933 QQLQKVQPPTPLLPSVK-VQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQ 991
Q+L+ ++ L +K S+P PP S Q +P PPP PP +
Sbjct: 1461 QELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGK 1520
Query: 992 PPPRPVH--LQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQ 1037
PP V P + S + +PP P PP PPP PPPP KPQ
Sbjct: 1521 PPGSIVRPSAPPARSSVPVTRPPVPI--PPPPPPP-PLPPPPPVIKPQ 1565
Score = 45.1 bits (105), Expect = 5e-04
Identities = 34/127 (26%), Positives = 55/127 (43%), Gaps = 12/127 (9%)
Query: 146 IVLMAEALEKLFLQKINELPT-EETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQAS- 203
++++++ ++ L+ EL E + + + K G + P S + NT+
Sbjct: 1445 VMVLSQRQHEIILKAAQELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPG 1504
Query: 204 --TPPQTQTPQPNPPPVQATPHPF--PAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQP 259
PP + P PPP+ P P+ P ++ V PP P+ PPP PP P P
Sbjct: 1505 MYPPPGSYRP---PPPMGKPPGSIVRPSAPP---ARSSVPVTRPPVPIPPPPPPPPLPPP 1558
Query: 260 PPAPAPQ 266
PP PQ
Sbjct: 1559 PPVIKPQ 1565
Score = 43.9 bits (102), Expect = 0.001
Identities = 69/298 (23%), Positives = 99/298 (33%), Gaps = 33/298 (11%)
Query: 1021 HPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTG-------HLREAPSPLMIHSPQM 1073
H PP PPPP A P+ +S + P S+G HL + +H QM
Sbjct: 13 HYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQM 72
Query: 1074 SQFQSLTHQSPPQQNVQPKKQELRAASVVQPQP----------LVVVKEEKI-HSPIIRS 1122
Q H PP P QP P L K+++ H +
Sbjct: 73 -QCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQ 131
Query: 1123 EPFSPSLRP-EPPKHPESIKAP--VHLPQRPEMKPVDVGRPVIRPPEQNAP--PPGAPDK 1177
P L P E PES P ++P P P PP + P PP P
Sbjct: 132 RDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQP-S 190
Query: 1178 DKQKQEPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEER 1237
Q ++ +AP + S + L PSS A S R ++ +
Sbjct: 191 PSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPS--------RPSQGHSKS 242
Query: 1238 EKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQ 1295
+ K ++QE + S + EQ + A E Q+QQ+ +Q
Sbjct: 243 QLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQ 300
Score = 40.8 bits (94), Expect = 0.009
Identities = 29/108 (26%), Positives = 41/108 (37%), Gaps = 13/108 (12%)
Query: 242 VPPQPLQTPPPVPP-------QPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADT 294
+PP PL PPPV P QP PPP P P P ++ Q + + + D
Sbjct: 81 LPPPPL-PPPPVMPGGGYGDWQPPPPPMPPPP-----GPALSYQKQQQYKHQMLHHQRDG 134
Query: 295 TTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHP 342
+ PP PP P + + + P +PP P + P
Sbjct: 135 PPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQP 182
Score = 39.3 bits (90), Expect = 0.026
Identities = 55/213 (25%), Positives = 72/213 (33%), Gaps = 53/213 (24%)
Query: 159 QKINELPTEETEIMIVQAKGR-----GRGRKETGTAKPGVSTV-PNTTQA-STPPQTQTP 211
Q + LP +E+ + ++ G R KP S V P+ A S+ P T+ P
Sbjct: 1484 QMADHLPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPP 1543
Query: 212 QPNPPPVQATPHPFPAVTPDLIVQTPVM------------------------------TV 241
P PPP P P P P + QT +
Sbjct: 1544 VPIPPP--PPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAA 1601
Query: 242 VPPQPLQTPPPVPPQ-PQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTI 300
+P P+ PPPV P P P P P S PP + T G R T I
Sbjct: 1602 IPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQT-----VDYGHGRDISTNKVEQI 1656
Query: 301 DPIHEPPSLPPEP-------KTTKLGQRRESSR 326
P E +L P+P +T GQR R
Sbjct: 1657 -PYGERITLRPDPLPERSTFETEHAGQRDRYDR 1688
Score = 38.9 bits (89), Expect = 0.034
Identities = 49/189 (25%), Positives = 61/189 (32%), Gaps = 62/189 (32%)
Query: 212 QPNPPPVQATPHPF---------------------PAVTPDLIVQTPVMTVVPP----QP 246
QP PPP+ P P P + P + P VPP P
Sbjct: 101 QPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPP 160
Query: 247 LQT--PPPVPP---------QPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRK---- 291
Q+ PPP PP QP PPA P P QS P P P + +
Sbjct: 161 SQSYMPPPQPPPSYYPPTSSQPYLPPAQ-PSPSQSPPSQSYLAPTPSYSSSSSSSQSYLS 219
Query: 292 -------ADTTTPTTIDPIHE--------PPSLPPEPKTTKLGQRRESSRPVKPPKKDVP 336
+ +P+ H PPS PP KTT P++ K+
Sbjct: 220 HSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTT------VQQEPLESGAKNKS 273
Query: 337 DSQQHPAPE 345
QQ APE
Sbjct: 274 TEQQQAAPE 282
Score = 33.9 bits (76), Expect = 1.1
Identities = 20/58 (34%), Positives = 24/58 (41%), Gaps = 5/58 (8%)
Query: 217 PVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPP--QPQPPPAPAPQPVQSHP 272
PV A P P V P + VP P PP+PP + PPP P +P P
Sbjct: 320 PVVAKDTPEPVKEE---VTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDP 374
Score = 33.1 bits (74), Expect = 1.9
Identities = 31/105 (29%), Positives = 42/105 (40%), Gaps = 17/105 (16%)
Query: 1075 QFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSP--SLRPE 1132
+ + L Q Q ++ E + A + PQ E ++ + R + P S RP
Sbjct: 1462 ELKMLREQKEQLQKMKDFGSEPQMADHLPPQ------ESRLQNTSSRPGMYPPPGSYRPP 1515
Query: 1133 PP--KHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAP 1175
PP K P SI P P R + PV RPP PPP P
Sbjct: 1516 PPMGKPPGSIVRPSAPPARSSV-------PVTRPPVPIPPPPPPP 1553
Score = 32.0 bits (71), Expect = 4.2
Identities = 15/36 (41%), Positives = 19/36 (52%), Gaps = 1/36 (2%)
Query: 195 TVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTP 230
TVP T+Q P ++ P P PPP + P P P P
Sbjct: 335 TVPATSQVPESPSSEEP-PLPPPNEEVPPPLPPEEP 369
Score = 31.2 bits (69), Expect = 7.1
Identities = 29/120 (24%), Positives = 45/120 (37%), Gaps = 17/120 (14%)
Query: 243 PPQPLQTPPPVP-PQPQPPPAPAPQPVQSHPP---IIAATPQPVKTKKGVKRKADTTTPT 298
PP P+ PPPV P+ P P + + P ++ Q + + +++
Sbjct: 15 PPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQC 74
Query: 299 TIDPIH-EPPSLPPEPKTT--KLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQLK 355
+ P H PP LPP P G + P+ PP P P S + +Q K
Sbjct: 75 VLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPP----------PGPALSYQKQQQYK 124
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.127 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,737,150
Number of Sequences: 37866
Number of extensions: 6706801
Number of successful extensions: 285472
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2474
Number of HSP's successfully gapped in prelim test: 2661
Number of HSP's that attempted gapping in prelim test: 46176
Number of HSP's gapped (non-prelim): 97496
length of query: 1362
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1247
effective length of database: 13,892,928
effective search space: 17324481216
effective search space used: 17324481216
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.