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Search of human proteins with 195222734
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|195222734 lymphoid enhancer-binding factor 1 isoform 3 [Homo
sapiens]
(386 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|195222734 lymphoid enhancer-binding factor 1 isoform 3 [Homo ... 816 0.0
gi|195222732 lymphoid enhancer-binding factor 1 isoform 2 [Homo ... 764 0.0
gi|7705917 lymphoid enhancer-binding factor 1 isoform 1 [Homo sa... 749 0.0
gi|226371627 transcription factor 7-like 2 isoform 6 [Homo sapiens] 416 e-116
gi|226371623 transcription factor 7-like 2 isoform 4 [Homo sapiens] 407 e-114
gi|170014696 transcription factor 7-like 2 isoform 2 [Homo sapiens] 396 e-110
gi|226371625 transcription factor 7-like 2 isoform 5 [Homo sapiens] 396 e-110
gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens] 379 e-105
gi|13786123 HMG-box transcription factor TCF-3 [Homo sapiens] 360 e-100
gi|226371620 transcription factor 7-like 2 isoform 3 [Homo sapiens] 353 2e-97
gi|42518080 transcription factor 7 (T-cell specific, HMG-box) is... 325 6e-89
gi|42518078 transcription factor 7 (T-cell specific, HMG-box) is... 269 4e-72
gi|47419938 transcription factor 7 (T-cell specific, HMG-box) is... 269 4e-72
gi|198442851 transcription factor 7 (T-cell specific, HMG-box) 6... 244 9e-65
gi|198442849 transcription factor 7 (T-cell specific, HMG-box) 5... 244 9e-65
gi|42518074 transcription factor 7 (T-cell specific, HMG-box) is... 244 9e-65
gi|42714657 transcription factor 7 (T-cell specific, HMG-box) is... 244 9e-65
gi|112421108 capicua homolog [Homo sapiens] 76 4e-14
gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Hom... 64 3e-10
gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Hom... 64 3e-10
gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo... 64 3e-10
gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo... 64 3e-10
gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo... 63 4e-10
gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo... 63 4e-10
gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo... 63 4e-10
gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo... 61 1e-09
gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Hom... 61 1e-09
gi|41406089 SRY-box 13 [Homo sapiens] 59 1e-08
gi|13899269 SRY-box 7 [Homo sapiens] 55 8e-08
gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens] 55 1e-07
>gi|195222734 lymphoid enhancer-binding factor 1 isoform 3 [Homo
sapiens]
Length = 386
Score = 816 bits (2107), Expect = 0.0
Identities = 386/386 (100%), Positives = 386/386 (100%)
Query: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE
Sbjct: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
Query: 61 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM 120
SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM
Sbjct: 61 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM 120
Query: 121 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS 180
NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS
Sbjct: 121 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS 180
Query: 181 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMIPGPPGPHTTGIPHPAIVTPQV 240
KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMIPGPPGPHTTGIPHPAIVTPQV
Sbjct: 181 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMIPGPPGPHTTGIPHPAIVTPQV 240
Query: 241 KQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAA 300
KQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAA
Sbjct: 241 KQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAA 300
Query: 301 INQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESAS 360
INQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESAS
Sbjct: 301 INQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESAS 360
Query: 361 GGKRSSFPTCKAKAATPGPLLEMEAC 386
GGKRSSFPTCKAKAATPGPLLEMEAC
Sbjct: 361 GGKRSSFPTCKAKAATPGPLLEMEAC 386
>gi|195222732 lymphoid enhancer-binding factor 1 isoform 2 [Homo
sapiens]
Length = 371
Score = 764 bits (1973), Expect = 0.0
Identities = 361/361 (100%), Positives = 361/361 (100%)
Query: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE
Sbjct: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
Query: 61 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM 120
SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM
Sbjct: 61 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM 120
Query: 121 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS 180
NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS
Sbjct: 121 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS 180
Query: 181 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMIPGPPGPHTTGIPHPAIVTPQV 240
KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMIPGPPGPHTTGIPHPAIVTPQV
Sbjct: 181 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMIPGPPGPHTTGIPHPAIVTPQV 240
Query: 241 KQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAA 300
KQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAA
Sbjct: 241 KQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAA 300
Query: 301 INQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESAS 360
INQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESAS
Sbjct: 301 INQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESAS 360
Query: 361 G 361
G
Sbjct: 361 G 361
>gi|7705917 lymphoid enhancer-binding factor 1 isoform 1 [Homo
sapiens]
Length = 399
Score = 749 bits (1934), Expect = 0.0
Identities = 361/389 (92%), Positives = 361/389 (92%), Gaps = 28/389 (7%)
Query: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE
Sbjct: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
Query: 61 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM 120
SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM
Sbjct: 61 SEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKGPSYSSYSGYIMMPNM 120
Query: 121 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS 180
NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS
Sbjct: 121 NNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNS 180
Query: 181 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGW--------------------------- 213
KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGW
Sbjct: 181 KQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWQGQPVYPITGGFRQPYPSSLSVDTSMS 240
Query: 214 -FSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK 272
FSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK
Sbjct: 241 RFSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIK 300
Query: 273 KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM 332
KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM
Sbjct: 301 KPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHM 360
Query: 333 QLYPGWSARDNYGKKKKRKREKLQESASG 361
QLYPGWSARDNYGKKKKRKREKLQESASG
Sbjct: 361 QLYPGWSARDNYGKKKKRKREKLQESASG 389
>gi|226371627 transcription factor 7-like 2 isoform 6 [Homo sapiens]
Length = 442
Score = 416 bits (1070), Expect = e-116
Identities = 240/453 (52%), Positives = 281/453 (62%), Gaps = 80/453 (17%)
Query: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
MPQL+GGGG +L A DE+I FKDEG+ Q+EK + E DLAD+KSSLVNE
Sbjct: 1 MPQLNGGGGD-----DLGANDELISFKDEGE-QEEK---SSENSSAERDLADVKSSLVNE 51
Query: 61 SEIIP-ASNGHEVARQAQTSQEPYHDKAREHPDDG-KHPDGGLYNKGPSYSSYSGYIMMP 118
SE +S+ E R+ E + DK+RE ++ K DGGL+ KGP Y Y +IM+P
Sbjct: 52 SETNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLF-KGPPYPGYP-FIMIP 109
Query: 119 NMNNDPYMSNGSLSP---------------------------------PIPRTSNKVPVV 145
++ + PY+ NGSLSP P SNKVPVV
Sbjct: 110 DLTS-PYLPNGSLSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVV 168
Query: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
Q H VHPLTPLITYS+EHF+PG+ P H+P+DV+ K G+ R P PDI +YPLSPG VG
Sbjct: 169 QHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVG 228
Query: 206 QITPPLGW---------------------------------FSHHMIPGPPGPHTTGIPH 232
QI PLGW F HM+P HTTGIPH
Sbjct: 229 QIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPH 288
Query: 233 PAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAE 292
PAIVTP VKQE +D +H + +KE+E K+PHIKKPLNAFMLYMKEMRA VVAE
Sbjct: 289 PAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAE 348
Query: 293 CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR 352
CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR
Sbjct: 349 CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR 408
Query: 353 EKLQESASGGKRSSFPTCKAKAATPGPLLEMEA 385
+K +G K+S+F T K KAA L+MEA
Sbjct: 409 DKQPGETNGEKKSAFATYKVKAAASAHPLQMEA 441
>gi|226371623 transcription factor 7-like 2 isoform 4 [Homo sapiens]
Length = 455
Score = 407 bits (1046), Expect = e-114
Identities = 240/466 (51%), Positives = 281/466 (60%), Gaps = 93/466 (19%)
Query: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
MPQL+GGGG +L A DE+I FKDEG+ Q+EK + E DLAD+KSSLVNE
Sbjct: 1 MPQLNGGGGD-----DLGANDELISFKDEGE-QEEK---SSENSSAERDLADVKSSLVNE 51
Query: 61 SEIIP-ASNGHEVARQAQTSQEPYHDKAREHPDDG-KHPDGGLYNKGPSYSSYSGYIMMP 118
SE +S+ E R+ E + DK+RE ++ K DGGL+ KGP Y Y +IM+P
Sbjct: 52 SETNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLF-KGPPYPGYP-FIMIP 109
Query: 119 NMNNDPYMSNGSLSP---------------------------------PIPRTSNKVPVV 145
++ + PY+ NGSLSP P SNKVPVV
Sbjct: 110 DLTS-PYLPNGSLSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVV 168
Query: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
Q H VHPLTPLITYS+EHF+PG+ P H+P+DV+ K G+ R P PDI +YPLSPG VG
Sbjct: 169 QHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVG 228
Query: 206 QITPPLGW-----------------------------FSHHMIPGPPGPHTTGIPHPAIV 236
QI PLGW F HM+P HTTGIPHPAIV
Sbjct: 229 QIPHPLGWQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIV 288
Query: 237 TPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLK 296
TP VKQE +D +H + +KE+E K+PHIKKPLNAFMLYMKEMRA VVAECTLK
Sbjct: 289 TPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLK 348
Query: 297 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQ 356
ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR+K
Sbjct: 349 ESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQP 408
Query: 357 ESA-----------------SGGKRSSFPTCKAKAATPGPLLEMEA 385
+G K+S+F T K KAA L+MEA
Sbjct: 409 GETNEHSECFLNPCLSLPPITGEKKSAFATYKVKAAASAHPLQMEA 454
>gi|170014696 transcription factor 7-like 2 isoform 2 [Homo sapiens]
Length = 596
Score = 396 bits (1018), Expect = e-110
Identities = 227/422 (53%), Positives = 264/422 (62%), Gaps = 80/422 (18%)
Query: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
MPQL+GGGG +L A DE+I FKDEG+ Q+EK + E DLAD+KSSLVNE
Sbjct: 1 MPQLNGGGGD-----DLGANDELISFKDEGE-QEEK---SSENSSAERDLADVKSSLVNE 51
Query: 61 SEIIP-ASNGHEVARQAQTSQEPYHDKAREHPDDG-KHPDGGLYNKGPSYSSYSGYIMMP 118
SE +S+ E R+ E + DK+RE ++ K DGGL+ KGP Y Y +IM+P
Sbjct: 52 SETNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLF-KGPPYPGYP-FIMIP 109
Query: 119 NMNNDPYMSNGSLSP---------------------------------PIPRTSNKVPVV 145
++ + PY+ NGSLSP P SNKVPVV
Sbjct: 110 DLTS-PYLPNGSLSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVV 168
Query: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
Q H VHPLTPLITYS+EHF+PG+ P H+P+DV+ K G+ R P PDI +YPLSPG VG
Sbjct: 169 QHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVG 228
Query: 206 QITPPLGW---------------------------------FSHHMIPGPPGPHTTGIPH 232
QI PLGW F HM+P HTTGIPH
Sbjct: 229 QIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPH 288
Query: 233 PAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAE 292
PAIVTP VKQE +D +H + +KE+E K+PHIKKPLNAFMLYMKEMRA VVAE
Sbjct: 289 PAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAE 348
Query: 293 CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR 352
CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR
Sbjct: 349 CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR 408
Query: 353 EK 354
+K
Sbjct: 409 DK 410
>gi|226371625 transcription factor 7-like 2 isoform 5 [Homo sapiens]
Length = 579
Score = 396 bits (1018), Expect = e-110
Identities = 227/422 (53%), Positives = 264/422 (62%), Gaps = 80/422 (18%)
Query: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
MPQL+GGGG +L A DE+I FKDEG+ Q+EK + E DLAD+KSSLVNE
Sbjct: 1 MPQLNGGGGD-----DLGANDELISFKDEGE-QEEK---SSENSSAERDLADVKSSLVNE 51
Query: 61 SEIIP-ASNGHEVARQAQTSQEPYHDKAREHPDDG-KHPDGGLYNKGPSYSSYSGYIMMP 118
SE +S+ E R+ E + DK+RE ++ K DGGL+ KGP Y Y +IM+P
Sbjct: 52 SETNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLF-KGPPYPGYP-FIMIP 109
Query: 119 NMNNDPYMSNGSLSP---------------------------------PIPRTSNKVPVV 145
++ + PY+ NGSLSP P SNKVPVV
Sbjct: 110 DLTS-PYLPNGSLSPTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSNKVPVV 168
Query: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
Q H VHPLTPLITYS+EHF+PG+ P H+P+DV+ K G+ R P PDI +YPLSPG VG
Sbjct: 169 QHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVG 228
Query: 206 QITPPLGW---------------------------------FSHHMIPGPPGPHTTGIPH 232
QI PLGW F HM+P HTTGIPH
Sbjct: 229 QIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPH 288
Query: 233 PAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAE 292
PAIVTP VKQE +D +H + +KE+E K+PHIKKPLNAFMLYMKEMRA VVAE
Sbjct: 289 PAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAE 348
Query: 293 CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR 352
CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR
Sbjct: 349 CTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR 408
Query: 353 EK 354
+K
Sbjct: 409 DK 410
>gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens]
Length = 602
Score = 379 bits (973), Expect = e-105
Identities = 227/445 (51%), Positives = 264/445 (59%), Gaps = 103/445 (23%)
Query: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
MPQL+GGGG +L A DE+I FKDEG+ Q+EK + E DLAD+KSSLVNE
Sbjct: 1 MPQLNGGGGD-----DLGANDELISFKDEGE-QEEK---SSENSSAERDLADVKSSLVNE 51
Query: 61 SEIIP-ASNGHEVARQAQTSQEPYHDKAREHPDDG-KHPDGGLYNKGPSYSSYSGYIMMP 118
SE +S+ E R+ E + DK+RE ++ K DGGL+ KGP Y Y +IM+P
Sbjct: 52 SETNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLF-KGPPYPGYP-FIMIP 109
Query: 119 NMNNDPYMSN---------------------------------------------GSL-- 131
++ + PY+ N GSL
Sbjct: 110 DLTS-PYLPNGSLSPTARTLHFQSGSTHYSAYKTIEHQIAVQYLQMKWPLLDVQAGSLQS 168
Query: 132 --------SP-PIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQ 182
SP P SNKVPVVQ H VHPLTPLITYS+EHF+PG+ P H+P+DV+ K
Sbjct: 169 RQALKDARSPSPAHIVSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKT 228
Query: 183 GMSRHPPAPDIPTFYPLSPGGVGQITPPLGW----------------------------- 213
G+ R P PDI +YPLSPG VGQI PLGW
Sbjct: 229 GIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNA 288
Query: 214 ----FSHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRP 269
F HM+P HTTGIPHPAIVTP VKQE +D +H + +KE+E K+P
Sbjct: 289 SMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKP 348
Query: 270 HIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQ 329
HIKKPLNAFMLYMKEMRA VVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQ
Sbjct: 349 HIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQ 408
Query: 330 LHMQLYPGWSARDNYGKKKKRKREK 354
LHMQLYPGWSARDNYGKKKKRKR+K
Sbjct: 409 LHMQLYPGWSARDNYGKKKKRKRDK 433
>gi|13786123 HMG-box transcription factor TCF-3 [Homo sapiens]
Length = 588
Score = 360 bits (925), Expect = e-100
Identities = 213/436 (48%), Positives = 262/436 (60%), Gaps = 89/436 (20%)
Query: 1 MPQLSGGGGGGGGDP---------------ELCATDEMIPFKDEGDPQKEKIFAEISHPE 45
MPQL GGGGGGGG +L A DE+IPF+DEG ++E S
Sbjct: 1 MPQLGGGGGGGGGGSGGGGGSSAGAAGGGDDLGANDELIPFQDEGGEEQEPSSDSAS--- 57
Query: 46 EEGDLADIKSSLVNESEIIPASNGHEVARQAQTSQEPYHDKAREHPDDGKHPDGGLYNKG 105
+ DL ++KSSLVNESE +S+ E R+ Q ++ + K R++ + + P + KG
Sbjct: 58 AQRDLDEVKSSLVNESENQSSSSDSEAERRPQPVRDTFQ-KPRDYFAEVRRPQDSAFFKG 116
Query: 106 PSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRT--------------------------- 138
P Y Y ++M+P++++ PY+SNG LSP RT
Sbjct: 117 PPYPGYP-FLMIPDLSS-PYLSNGPLSPGGARTYLQMKWPLLDVPSSATVKDTRSPSPAH 174
Query: 139 -SNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFY 197
SNKVPVVQ H +HPLTPLITYS++HFSPGS P+H+ +++ K G+ R P ++ +Y
Sbjct: 175 LSNKVPVVQHPHHMHPLTPLITYSNDHFSPGSPPTHLSPEIDPKTGIPRPPHPSELSPYY 234
Query: 198 PLSPGGVGQITPPLGW-------------------------------------FSHHMI- 219
PLSPG VGQI PLGW FS HM+
Sbjct: 235 PLSPGAVGQIPHPLGWLVPQQGQPMYSLPPGGFRHPYPALAMNASMSSLVSSRFSPHMVA 294
Query: 220 PGPPGPHTTGIPHPAIVTPQVKQEH-PHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAF 278
P PG T+GIPHPAIV+P VKQE P + S + VK +KE+E K+PH+KKPLNAF
Sbjct: 295 PAHPGLPTSGIPHPAIVSPIVKQEPAPPSLSPAVSVKSPVTVKKEEE-KKPHVKKPLNAF 353
Query: 279 MLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGW 338
MLYMKEMRA VVAECTLKESAAINQILGR+WH LSREEQAKYYELARKERQLH QLYP W
Sbjct: 354 MLYMKEMRAKVVAECTLKESAAINQILGRKWHNLSREEQAKYYELARKERQLHSQLYPTW 413
Query: 339 SARDNYGKKKKRKREK 354
SARDNYGKKKKRKREK
Sbjct: 414 SARDNYGKKKKRKREK 429
>gi|226371620 transcription factor 7-like 2 isoform 3 [Homo sapiens]
Length = 489
Score = 353 bits (905), Expect = 2e-97
Identities = 230/502 (45%), Positives = 273/502 (54%), Gaps = 131/502 (26%)
Query: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
MPQL+GGGG +L A DE+I FKDEG+ Q+EK + E DLAD+KSSLVNE
Sbjct: 1 MPQLNGGGGD-----DLGANDELISFKDEGE-QEEK---SSENSSAERDLADVKSSLVNE 51
Query: 61 SEIIP-ASNGHEVARQAQTSQEPYHDKAREHPDD-GKHPDGGLYNKGPSYSSYSGYIMMP 118
SE +S+ E R+ E + DK+RE ++ K DGGL+ KGP Y Y +IM+P
Sbjct: 52 SETNQNSSSDSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLF-KGPPYPGYP-FIMIP 109
Query: 119 NMNNDPYMSNGSLSPPIPRT--SNKVPVV-------------------QPSHAVHPLTPL 157
++ + PY+ NGSLS P RT K P++ P+H V PL P
Sbjct: 110 DLTS-PYLPNGSLS-PTARTYLQMKWPLLDVQAGSLQSRQALKDARSPSPAHIVSPL-PC 166
Query: 158 IT--YSDEHFSPGS------------------------------------HPSHI----- 174
T + +HF P S HP H+
Sbjct: 167 CTQGHDCQHFYPPSDFTVSTQVFRDMKRSHSLQKVGEPWCIESNKVPVVQHPHHVHPLTP 226
Query: 175 ------------------PSDVNSKQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGW--- 213
P+DV+ K G+ R P PDI +YPLSPG VGQI PLGW
Sbjct: 227 LITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDISPYYPLSPGTVGQIPHPLGWLVP 286
Query: 214 ------------------------------FSHHMIPGPPGPHTTGIPHPAIVTPQVKQE 243
F HM+P HTTGIPHPAIVTP VKQE
Sbjct: 287 QQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPPHHTLHTTGIPHPAIVTPTVKQE 346
Query: 244 HPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQ 303
+D +H + +KE+E K+PHIKKPLNAFMLYMKEMRA VVAECTLKESAAINQ
Sbjct: 347 SSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLYMKEMRAKVVAECTLKESAAINQ 406
Query: 304 ILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESASGGK 363
ILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKR+K +G K
Sbjct: 407 ILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKKRKRDKQPGETNGEK 466
Query: 364 RSSFPTCKAKAATPGPLLEMEA 385
+S+F T K KAA L+MEA
Sbjct: 467 KSAFATYKVKAAASAHPLQMEA 488
>gi|42518080 transcription factor 7 (T-cell specific, HMG-box)
isoform 1 [Homo sapiens]
Length = 384
Score = 325 bits (832), Expect = 6e-89
Identities = 198/403 (49%), Positives = 245/403 (60%), Gaps = 42/403 (10%)
Query: 1 MPQLSGGGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNE 60
MPQL GGGG GG +L A DE++ F+DEG+ Q +K + PE DLA++KSSLVNE
Sbjct: 1 MPQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPER--DLAELKSSLVNE 58
Query: 61 SEIIPASNG--------------HEVARQAQTSQEPYHDKAREHPDDG-KHPD--GGLYN 103
SE G E + +Q + DK E +DG K P+ G+Y
Sbjct: 59 SEGAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLEDGLKAPECTSGMYK 118
Query: 104 KGPSYSSYSGYIMMPNMNNDPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDE 163
+ + YS + ++ M+ P G P P P+ + + H + L Y E
Sbjct: 119 E----TVYSAFNLL--MHYPPPSGAGQHPQPQP------PLHKANQPPHGVPQLSLY--E 164
Query: 164 HFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVGQITPPLGWFSHHMI---P 220
HF+ HP+ P+D++ KQ + R PD+ FY L+ G +GQ+ + WF+H +
Sbjct: 165 HFN-SPHPTPAPADISQKQ-VHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGS 222
Query: 221 GPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKPLNAFML 280
G PG H IPHPAIV P KQE D +L K Q E + E+E K+P IKKPLNAFML
Sbjct: 223 GVPG-HPAAIPHPAIVPPSGKQELQPFDRNL---KTQAESKAEKEAKKPTIKKPLNAFML 278
Query: 281 YMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSA 340
YMKEMRA V+AECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSA
Sbjct: 279 YMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSA 338
Query: 341 RDNYGKKKKRKREKLQESASGGKRSSFPTCKAKAATPGPLLEM 383
RDNYGKKK+R REK QES +GGKR++F T KAA P P L M
Sbjct: 339 RDNYGKKKRRSREKHQESTTGGKRNAFGTYPEKAAAPAPFLPM 381
>gi|42518078 transcription factor 7 (T-cell specific, HMG-box)
isoform 2 [Homo sapiens]
Length = 269
Score = 269 bits (687), Expect = 4e-72
Identities = 146/241 (60%), Positives = 169/241 (70%), Gaps = 14/241 (5%)
Query: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
QP H V L+ EHF+ HP+ P+D++ KQ + R PD+ FY L+ G +G
Sbjct: 37 QPPHGVPQLSLY-----EHFN-SPHPTPAPADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
Query: 206 QITPPLGWFSHHMI---PGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRK 262
Q+ + WF+H + G PG H IPHPAIV P KQE D +L K Q E +
Sbjct: 90 QLPHTVSWFTHPSLMLGSGVPG-HPAAIPHPAIVPPSGKQELQPFDRNL---KTQAESKA 145
Query: 263 EQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYE 322
E+E K+P IKKPLNAFMLYMKEMRA V+AECTLKESAAINQILGRRWHALSREEQAKYYE
Sbjct: 146 EKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYE 205
Query: 323 LARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESASGGKRSSFPTCKAKAATPGPLLE 382
LARKERQLHMQLYPGWSARDNYGKKK+R REK QES +GGKR++F T KAA P P L
Sbjct: 206 LARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTGGKRNAFGTYPEKAAAPAPFLP 265
Query: 383 M 383
M
Sbjct: 266 M 266
>gi|47419938 transcription factor 7 (T-cell specific, HMG-box)
isoform 2 [Homo sapiens]
Length = 269
Score = 269 bits (687), Expect = 4e-72
Identities = 146/241 (60%), Positives = 169/241 (70%), Gaps = 14/241 (5%)
Query: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
QP H V L+ EHF+ HP+ P+D++ KQ + R PD+ FY L+ G +G
Sbjct: 37 QPPHGVPQLSLY-----EHFN-SPHPTPAPADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
Query: 206 QITPPLGWFSHHMI---PGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRK 262
Q+ + WF+H + G PG H IPHPAIV P KQE D +L K Q E +
Sbjct: 90 QLPHTVSWFTHPSLMLGSGVPG-HPAAIPHPAIVPPSGKQELQPFDRNL---KTQAESKA 145
Query: 263 EQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYE 322
E+E K+P IKKPLNAFMLYMKEMRA V+AECTLKESAAINQILGRRWHALSREEQAKYYE
Sbjct: 146 EKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYE 205
Query: 323 LARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESASGGKRSSFPTCKAKAATPGPLLE 382
LARKERQLHMQLYPGWSARDNYGKKK+R REK QES +GGKR++F T KAA P P L
Sbjct: 206 LARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTGGKRNAFGTYPEKAAAPAPFLP 265
Query: 383 M 383
M
Sbjct: 266 M 266
>gi|198442851 transcription factor 7 (T-cell specific, HMG-box) 6
[Homo sapiens]
Length = 250
Score = 244 bits (623), Expect = 9e-65
Identities = 133/218 (61%), Positives = 154/218 (70%), Gaps = 14/218 (6%)
Query: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
QP H V L+ EHF+ HP+ P+D++ KQ + R PD+ FY L+ G +G
Sbjct: 37 QPPHGVPQLSLY-----EHFN-SPHPTPAPADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
Query: 206 QITPPLGWFSHHMI---PGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRK 262
Q+ + WF+H + G PG H IPHPAIV P KQE D +L K Q E +
Sbjct: 90 QLPHTVSWFTHPSLMLGSGVPG-HPAAIPHPAIVPPSGKQELQPFDRNL---KTQAESKA 145
Query: 263 EQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYE 322
E+E K+P IKKPLNAFMLYMKEMRA V+AECTLKESAAINQILGRRWHALSREEQAKYYE
Sbjct: 146 EKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYE 205
Query: 323 LARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESAS 360
LARKERQLHMQLYPGWSARDNYGKKK+R REK QES +
Sbjct: 206 LARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTT 243
>gi|198442849 transcription factor 7 (T-cell specific, HMG-box) 5
[Homo sapiens]
Length = 366
Score = 244 bits (623), Expect = 9e-65
Identities = 133/218 (61%), Positives = 154/218 (70%), Gaps = 14/218 (6%)
Query: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
QP H V L+ EHF+ HP+ P+D++ KQ + R PD+ FY L+ G +G
Sbjct: 37 QPPHGVPQLSLY-----EHFN-SPHPTPAPADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
Query: 206 QITPPLGWFSHHMI---PGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRK 262
Q+ + WF+H + G PG H IPHPAIV P KQE D +L K Q E +
Sbjct: 90 QLPHTVSWFTHPSLMLGSGVPG-HPAAIPHPAIVPPSGKQELQPFDRNL---KTQAESKA 145
Query: 263 EQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYE 322
E+E K+P IKKPLNAFMLYMKEMRA V+AECTLKESAAINQILGRRWHALSREEQAKYYE
Sbjct: 146 EKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYE 205
Query: 323 LARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESAS 360
LARKERQLHMQLYPGWSARDNYGKKK+R REK QES +
Sbjct: 206 LARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTT 243
>gi|42518074 transcription factor 7 (T-cell specific, HMG-box)
isoform 3 [Homo sapiens]
Length = 269
Score = 244 bits (623), Expect = 9e-65
Identities = 133/218 (61%), Positives = 154/218 (70%), Gaps = 14/218 (6%)
Query: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
QP H V L+ EHF+ HP+ P+D++ KQ + R PD+ FY L+ G +G
Sbjct: 37 QPPHGVPQLSLY-----EHFN-SPHPTPAPADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
Query: 206 QITPPLGWFSHHMI---PGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRK 262
Q+ + WF+H + G PG H IPHPAIV P KQE D +L K Q E +
Sbjct: 90 QLPHTVSWFTHPSLMLGSGVPG-HPAAIPHPAIVPPSGKQELQPFDRNL---KTQAESKA 145
Query: 263 EQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYE 322
E+E K+P IKKPLNAFMLYMKEMRA V+AECTLKESAAINQILGRRWHALSREEQAKYYE
Sbjct: 146 EKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYE 205
Query: 323 LARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESAS 360
LARKERQLHMQLYPGWSARDNYGKKK+R REK QES +
Sbjct: 206 LARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTT 243
>gi|42714657 transcription factor 7 (T-cell specific, HMG-box)
isoform 4 [Homo sapiens]
Length = 268
Score = 244 bits (623), Expect = 9e-65
Identities = 133/218 (61%), Positives = 154/218 (70%), Gaps = 14/218 (6%)
Query: 146 QPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPAPDIPTFYPLSPGGVG 205
QP H V L+ EHF+ HP+ P+D++ KQ + R PD+ FY L+ G +G
Sbjct: 37 QPPHGVPQLSLY-----EHFN-SPHPTPAPADISQKQ-VHRPLQTPDLSGFYSLTSGSMG 89
Query: 206 QITPPLGWFSHHMI---PGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRK 262
Q+ + WF+H + G PG H IPHPAIV P KQE D +L K Q E +
Sbjct: 90 QLPHTVSWFTHPSLMLGSGVPG-HPAAIPHPAIVPPSGKQELQPFDRNL---KTQAESKA 145
Query: 263 EQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYE 322
E+E K+P IKKPLNAFMLYMKEMRA V+AECTLKESAAINQILGRRWHALSREEQAKYYE
Sbjct: 146 EKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYE 205
Query: 323 LARKERQLHMQLYPGWSARDNYGKKKKRKREKLQESAS 360
LARKERQLHMQLYPGWSARDNYGKKK+R REK QES +
Sbjct: 206 LARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTT 243
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 76.3 bits (186), Expect = 4e-14
Identities = 68/277 (24%), Positives = 121/277 (43%), Gaps = 30/277 (10%)
Query: 134 PIPRTSNKVPVVQPSHAVHPLT-PLITYSDEHFSPGSHPSHIPSDVNSKQGMSRHPPA-- 190
P S P VQPS A P + P+ + + + + +H + PP
Sbjct: 42 PFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGAT 101
Query: 191 -PDIPTFYPLSPGGV---GQITPPLGWFSHHMIPGPPGP----HTTGIPHP----AIVTP 238
P+ P P P GV G+ PP + GPPG T H +I++P
Sbjct: 102 CPESPGPGPPHPLGVVESGKGPPPT---TEEEASGPPGEPRLDSETESDHDDAFLSIMSP 158
Query: 239 QVKQEHP---HTDSDLMHVKPQHEQRKEQEPKRP------HIKKPLNAFMLYMKEMRANV 289
+++ P L + + + E++ + P HI++P+NAFM++ K RA V
Sbjct: 159 EIQLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRALV 218
Query: 290 VAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKK 349
+++ +++ILG W+AL +E+ KY++LA + ++ H + +P W + KK
Sbjct: 219 HQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSS 278
Query: 350 RKREKLQESASGGKRSSFPTCKAK---AATPGPLLEM 383
+ + +GG + + ++ AA PG E+
Sbjct: 279 SEAKPTSLGLAGGHKETRERSMSETGTAAAPGVSSEL 315
>gi|224967054 SRY (sex determining region Y)-box 6 isoform 4 [Homo
sapiens]
Length = 841
Score = 63.5 bits (153), Expect = 3e-10
Identities = 30/84 (35%), Positives = 51/84 (60%), Gaps = 6/84 (7%)
Query: 269 PHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKER 328
PHIK+P+NAFM++ K+ R ++ ++ I++ILG RW ++S +E+ YYE +
Sbjct: 632 PHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLS 691
Query: 329 QLHMQLYPGWSARDNYGKKKKRKR 352
++H++ YP NY K + KR
Sbjct: 692 KIHLEKYP------NYKYKPRPKR 709
>gi|224967050 SRY (sex determining region Y)-box 6 isoform 3 [Homo
sapiens]
Length = 801
Score = 63.5 bits (153), Expect = 3e-10
Identities = 30/84 (35%), Positives = 51/84 (60%), Gaps = 6/84 (7%)
Query: 269 PHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKER 328
PHIK+P+NAFM++ K+ R ++ ++ I++ILG RW ++S +E+ YYE +
Sbjct: 592 PHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLS 651
Query: 329 QLHMQLYPGWSARDNYGKKKKRKR 352
++H++ YP NY K + KR
Sbjct: 652 KIHLEKYP------NYKYKPRPKR 669
>gi|70909338 SRY (sex determining region Y)-box 6 isoform 1 [Homo
sapiens]
Length = 804
Score = 63.5 bits (153), Expect = 3e-10
Identities = 30/84 (35%), Positives = 51/84 (60%), Gaps = 6/84 (7%)
Query: 269 PHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKER 328
PHIK+P+NAFM++ K+ R ++ ++ I++ILG RW ++S +E+ YYE +
Sbjct: 595 PHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLS 654
Query: 329 QLHMQLYPGWSARDNYGKKKKRKR 352
++H++ YP NY K + KR
Sbjct: 655 KIHLEKYP------NYKYKPRPKR 672
>gi|71037389 SRY (sex determining region Y)-box 6 isoform 2 [Homo
sapiens]
Length = 808
Score = 63.5 bits (153), Expect = 3e-10
Identities = 30/84 (35%), Positives = 51/84 (60%), Gaps = 6/84 (7%)
Query: 269 PHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKER 328
PHIK+P+NAFM++ K+ R ++ ++ I++ILG RW ++S +E+ YYE +
Sbjct: 599 PHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKSMSNQEKQPYYEEQARLS 658
Query: 329 QLHMQLYPGWSARDNYGKKKKRKR 352
++H++ YP NY K + KR
Sbjct: 659 KIHLEKYP------NYKYKPRPKR 676
>gi|30061558 SRY (sex determining region Y)-box 5 isoform c [Homo
sapiens]
Length = 377
Score = 63.2 bits (152), Expect = 4e-10
Identities = 34/139 (24%), Positives = 70/139 (50%), Gaps = 16/139 (11%)
Query: 258 HEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQ 317
+ + + + PHIK+P+NAFM++ K+ R ++ ++ I++ILG RW A++ E+
Sbjct: 157 YRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEK 216
Query: 318 AKYYELARKERQLHMQLYPGWSARDN-------YGKK---------KKRKREKLQESASG 361
YYE + + H++ YP + + GKK + +R+++++ +
Sbjct: 217 QPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNV 276
Query: 362 GKRSSFPTCKAKAATPGPL 380
G+++ P A PG +
Sbjct: 277 GQQAQIPIATAGVVYPGAI 295
>gi|23308715 SRY (sex determining region Y)-box 5 isoform b [Homo
sapiens]
Length = 750
Score = 63.2 bits (152), Expect = 4e-10
Identities = 34/139 (24%), Positives = 70/139 (50%), Gaps = 16/139 (11%)
Query: 258 HEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQ 317
+ + + + PHIK+P+NAFM++ K+ R ++ ++ I++ILG RW A++ E+
Sbjct: 530 YRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEK 589
Query: 318 AKYYELARKERQLHMQLYPGWSARDN-------YGKK---------KKRKREKLQESASG 361
YYE + + H++ YP + + GKK + +R+++++ +
Sbjct: 590 QPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNV 649
Query: 362 GKRSSFPTCKAKAATPGPL 380
G+++ P A PG +
Sbjct: 650 GQQAQIPIATAGVVYPGAI 668
>gi|23308713 SRY (sex determining region Y)-box 5 isoform a [Homo
sapiens]
Length = 763
Score = 63.2 bits (152), Expect = 4e-10
Identities = 34/139 (24%), Positives = 70/139 (50%), Gaps = 16/139 (11%)
Query: 258 HEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQ 317
+ + + + PHIK+P+NAFM++ K+ R ++ ++ I++ILG RW A++ E+
Sbjct: 543 YRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNLEK 602
Query: 318 AKYYELARKERQLHMQLYPGWSARDN-------YGKK---------KKRKREKLQESASG 361
YYE + + H++ YP + + GKK + +R+++++ +
Sbjct: 603 QPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYFNV 662
Query: 362 GKRSSFPTCKAKAATPGPL 380
G+++ P A PG +
Sbjct: 663 GQQAQIPIATAGVVYPGAI 681
>gi|5902112 SRY (sex determining region Y)-box 30 isoform b [Homo
sapiens]
Length = 501
Score = 61.2 bits (147), Expect = 1e-09
Identities = 27/80 (33%), Positives = 48/80 (60%)
Query: 270 HIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQ 329
H+K+P+NAFM++ + R + +A I+ LG W+ LS E++ YY+ A+K ++
Sbjct: 336 HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKE 395
Query: 330 LHMQLYPGWSARDNYGKKKK 349
H + +PGW + GK+K+
Sbjct: 396 KHREEFPGWVYQPRPGKRKR 415
>gi|30581117 SRY (sex determining region Y)-box 30 isoform a [Homo
sapiens]
Length = 753
Score = 61.2 bits (147), Expect = 1e-09
Identities = 27/80 (33%), Positives = 48/80 (60%)
Query: 270 HIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQ 329
H+K+P+NAFM++ + R + +A I+ LG W+ LS E++ YY+ A+K ++
Sbjct: 336 HVKRPMNAFMVWARIHRPALAKANPAANNAEISVQLGLEWNKLSEEQKKPYYDEAQKIKE 395
Query: 330 LHMQLYPGWSARDNYGKKKK 349
H + +PGW + GK+K+
Sbjct: 396 KHREEFPGWVYQPRPGKRKR 415
>gi|41406089 SRY-box 13 [Homo sapiens]
Length = 622
Score = 58.5 bits (140), Expect = 1e-08
Identities = 34/107 (31%), Positives = 58/107 (54%), Gaps = 10/107 (9%)
Query: 270 HIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQ 329
HIK+P+NAFM++ K+ R ++ +++I++ILG RW +++ +E+ YYE + +
Sbjct: 423 HIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSR 482
Query: 330 LHMQLYPGWSARDNYGKKKKRKREKLQESASGGKRSSFPTCKAKAAT 376
H++ YP +Y K + KR + E GKR KA T
Sbjct: 483 QHLEKYP------DYKYKPRPKRTCIVE----GKRLRVGEYKALMRT 519
>gi|13899269 SRY-box 7 [Homo sapiens]
Length = 388
Score = 55.5 bits (132), Expect = 8e-08
Identities = 26/80 (32%), Positives = 47/80 (58%)
Query: 271 IKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQL 330
I++P+NAFM++ K+ R + + +A ++++LG+ W AL+ ++ Y + A + R
Sbjct: 45 IRRPMNAFMVWAKDERKRLAVQNPDLHNAELSKMLGKSWKALTLSQKRPYVDEAERLRLQ 104
Query: 331 HMQLYPGWSARDNYGKKKKR 350
HMQ YP + R K+ KR
Sbjct: 105 HMQDYPNYKYRPRRKKQAKR 124
>gi|21264339 SRY (sex determining region Y)-box 12 [Homo sapiens]
Length = 315
Score = 55.1 bits (131), Expect = 1e-07
Identities = 37/119 (31%), Positives = 56/119 (47%), Gaps = 10/119 (8%)
Query: 270 HIKKPLNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQ 329
HIK+P+NAFM++ + R ++ + +A I++ LGRRW L E+ + A + R
Sbjct: 39 HIKRPMNAFMVWSQHERRKIMDQWPDMHNAEISKRLGRRWQLLQDSEKIPFVREAERLRL 98
Query: 330 LHMQLYPGWSARDNYGKKKK----RKREKLQESASGGKR----SSFPTCKAKAATPGPL 380
HM YP + R KK K + R + + GG R P + A GPL
Sbjct: 99 KHMADYPDYKYRPR--KKSKGAPAKARPRPPGGSGGGSRLKPGPQLPGRGGRRAAGGPL 155
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.132 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,846,417
Number of Sequences: 37866
Number of extensions: 1172683
Number of successful extensions: 6336
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 93
Number of HSP's successfully gapped in prelim test: 276
Number of HSP's that attempted gapping in prelim test: 5707
Number of HSP's gapped (non-prelim): 859
length of query: 386
length of database: 18,247,518
effective HSP length: 104
effective length of query: 282
effective length of database: 14,309,454
effective search space: 4035266028
effective search space used: 4035266028
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.