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Search of human proteins with 113416879
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|113416879 PREDICTED: hypothetical protein [Homo sapiens]
(175 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|113416879 PREDICTED: hypothetical protein [Homo sapiens] 379 e-106
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 67 1e-11
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 62 2e-10
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 62 3e-10
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 61 6e-10
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 61 6e-10
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 61 6e-10
gi|7706501 WW domain binding protein 11 [Homo sapiens] 60 7e-10
gi|39812378 RAN binding protein 9 [Homo sapiens] 59 2e-09
gi|11386183 WAS protein family, member 2 [Homo sapiens] 59 2e-09
gi|110832843 TBP-associated factor 4 [Homo sapiens] 59 3e-09
gi|60460889 Myb protein P42POP [Homo sapiens] 59 3e-09
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 59 3e-09
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 58 4e-09
gi|19924099 synapsin I isoform Ia [Homo sapiens] 57 6e-09
gi|19924097 synapsin I isoform Ib [Homo sapiens] 57 6e-09
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 57 8e-09
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 57 8e-09
gi|22027541 programmed cell death 7 [Homo sapiens] 57 8e-09
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 57 8e-09
gi|21704281 junctophilin 2 isoform 1 [Homo sapiens] 57 1e-08
gi|33356148 formin-like 1 [Homo sapiens] 56 1e-08
gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 56 2e-08
gi|18079216 CASK interacting protein 1 [Homo sapiens] 56 2e-08
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 56 2e-08
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 56 2e-08
gi|160707881 formin 2 [Homo sapiens] 55 2e-08
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 55 2e-08
gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo sa... 55 3e-08
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 55 3e-08
>gi|113416879 PREDICTED: hypothetical protein [Homo sapiens]
Length = 175
Score = 379 bits (974), Expect = e-106
Identities = 175/175 (100%), Positives = 175/175 (100%)
Query: 1 MPNKASGRRQGRARGRPHSQVSLARRAPLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPP 60
MPNKASGRRQGRARGRPHSQVSLARRAPLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPP
Sbjct: 1 MPNKASGRRQGRARGRPHSQVSLARRAPLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPP 60
Query: 61 AARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAP 120
AARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAP
Sbjct: 61 AARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAP 120
Query: 121 APGRDALRLPPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRPAPRPGHAQ 175
APGRDALRLPPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRPAPRPGHAQ
Sbjct: 121 APGRDALRLPPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRPAPRPGHAQ 175
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 66.6 bits (161), Expect = 1e-11
Identities = 49/162 (30%), Positives = 61/162 (37%), Gaps = 19/162 (11%)
Query: 26 RAPLMFGPGLRDPPPPRPAPPR-------PGEEPGNRHPPPPAARTHPGSCRARCPSPAA 78
R P+ GPG P PP P PP P ++P + PPP HP + + P P
Sbjct: 44 RGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPP 103
Query: 79 GGLRGPWTA-----APGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDAL------ 127
P A APG A +++A P + PGS P P
Sbjct: 104 QDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPT-SGAPPGSGPGPTPTPPPAVTSAPP 162
Query: 128 RLPPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRPAP 169
PPP PP P PP P +A P P P P+ P P
Sbjct: 163 GAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGP 204
Score = 33.5 bits (75), Expect = 0.097
Identities = 37/122 (30%), Positives = 43/122 (35%), Gaps = 21/122 (17%)
Query: 27 APLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWT 86
AP GPG PPP PG P P P + P + P AGG P
Sbjct: 141 APPGSGPGPTPTPPPAVTSAPPGAPP-----PTPPSSGVPTT------PPQAGGPPPPPA 189
Query: 87 AAPG-RQRADEGAAAARPERQRVWARRLPGSAAAPAP-GRDALRLPPPPPPPPERPRLPP 144
A PG +G P+ ++PG P P G L P P PP R P
Sbjct: 190 AVPGPGPGPKQGPGPGGPK-----GGKMPG---GPKPGGGPGLSTPGGHPKPPHRGGGEP 241
Query: 145 AG 146
G
Sbjct: 242 RG 243
Score = 31.2 bits (69), Expect = 0.48
Identities = 20/65 (30%), Positives = 21/65 (32%), Gaps = 6/65 (9%)
Query: 114 PGSAAAPAPGRDALRLPPP--PPPPPERPRLPPAGLAGGPADSAPPSP----APAPRSRP 167
P P P + PPP PPP P PP PP P P P
Sbjct: 56 PKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGP 115
Query: 168 APRPG 172
P PG
Sbjct: 116 GPAPG 120
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 62.4 bits (150), Expect = 2e-10
Identities = 49/138 (35%), Positives = 55/138 (39%), Gaps = 30/138 (21%)
Query: 38 PPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADEG 97
PPP R PP P P N PPPP AR R P P + R P TAAP
Sbjct: 280 PPPSRGGPPPPPPPPHNSGPPPPPARG-----RGAPPPPPS---RAP-TAAP------PP 324
Query: 98 AAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPP---PERPRLPPAGLAGGPADS 154
+RP S A P P + + PPPP P P P PP + G +
Sbjct: 325 PPPSRP------------SVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVA 372
Query: 155 APPSPAPAPRSRPAPRPG 172
PP P P P P P PG
Sbjct: 373 PPPPPPPPPPPGPPPPPG 390
Score = 45.4 bits (106), Expect = 2e-05
Identities = 25/55 (45%), Positives = 28/55 (50%), Gaps = 6/55 (10%)
Query: 119 APAPGRDALRLPPPPPPPPER--PRLPPAGLAGGPADSAPPSPAPAPRSRPAPRP 171
AP P + PPPPPPPP P PPA G P PP P+ AP + P P P
Sbjct: 276 APPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAP----PPPPSRAPTAAPPPPP 326
Score = 38.5 bits (88), Expect = 0.003
Identities = 43/137 (31%), Positives = 52/137 (37%), Gaps = 39/137 (28%)
Query: 28 PLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTA 87
P + G G PPPP P PP PG PPPP PG P+ G + P TA
Sbjct: 363 PSVLGVGPVAPPPPPPPPPPPG-------PPPP-----PG-------LPSDGDHQVPTTA 403
Query: 88 APGRQRAD---EGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPERPRLPP 144
D EGA + E+ S GRDAL R +
Sbjct: 404 GNKAALLDQIREGAQLKKVEQ---------NSRPVSCSGRDALL-------DQIRQGIQL 447
Query: 145 AGLAGGPADSAPPSPAP 161
+A G +S PP+PAP
Sbjct: 448 KSVADG-QESTPPTPAP 463
Score = 36.2 bits (82), Expect = 0.015
Identities = 20/52 (38%), Positives = 23/52 (44%), Gaps = 13/52 (25%)
Query: 124 RDALRLPPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRPAPRPGHAQ 175
++ LR PPPPPP R GGP PP P P S P P P +
Sbjct: 269 KNELRRQAPPPPPPSR---------GGP----PPPPPPPHNSGPPPPPARGR 307
Score = 35.4 bits (80), Expect = 0.025
Identities = 24/75 (32%), Positives = 29/75 (38%), Gaps = 1/75 (1%)
Query: 97 GAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPERPRLPPAGLAGGPADSAP 156
G A + E +R P S P P PPPPP PP + P +AP
Sbjct: 264 GVEAVKNELRRQAPPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPT-AAP 322
Query: 157 PSPAPAPRSRPAPRP 171
P P P+ S P P
Sbjct: 323 PPPPPSRPSVAVPPP 337
Score = 26.9 bits (58), Expect = 9.0
Identities = 17/48 (35%), Positives = 19/48 (39%), Gaps = 1/48 (2%)
Query: 15 GRPHSQVSLARRAPLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPAA 62
G P S+ P+ P PPPP P PP PG H P A
Sbjct: 357 GPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPP-PGLPSDGDHQVPTTA 403
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 62.0 bits (149), Expect = 3e-10
Identities = 63/181 (34%), Positives = 68/181 (37%), Gaps = 30/181 (16%)
Query: 3 NKASGRRQGRARGRPHSQVSLARRAPLMFGPGLRDPPPPRPA---PPRPG----EEPGNR 55
++A+ + GR RGR V R P GPG PPPP PA PPRP PG
Sbjct: 193 SRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPG--GPPPPFPAGQTPPRPPLGPPGPPGPP 250
Query: 56 HPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPG 115
PPPP P P G P PG+ G P LP
Sbjct: 251 GPPPPGQVLPP----PLAGPPNRGDRPPPPVLFPGQPF---GQPPLGP---------LPP 294
Query: 116 SAAAPAPGRDALRLPPPP---PPPPERPRLP-PAGLAGGPADSAPPSPAPA-PRSRPAPR 170
P PG PPPP PPPP P P P G G P APP P P P P
Sbjct: 295 GPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPA 354
Query: 171 P 171
P
Sbjct: 355 P 355
Score = 48.5 bits (114), Expect = 3e-06
Identities = 45/131 (34%), Positives = 49/131 (37%), Gaps = 11/131 (8%)
Query: 49 GEEPGNRHPPPP-----AARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADEGAAAARP 103
G+ G PP AA G R R P GG R P A PG A P
Sbjct: 178 GQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGP-PPPFPAGQTP 236
Query: 104 ERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPER-PRLPPAGLAGGPADSAPPSPAPA 162
R + PG P PG+ LPPP PP R R PP L G PP P
Sbjct: 237 PRPPLGPPGPPGPPGPPPPGQV---LPPPLAGPPNRGDRPPPPVLFPGQPFGQPPL-GPL 292
Query: 163 PRSRPAPRPGH 173
P P P PG+
Sbjct: 293 PPGPPPPVPGY 303
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 60.8 bits (146), Expect = 6e-10
Identities = 60/179 (33%), Positives = 65/179 (36%), Gaps = 37/179 (20%)
Query: 22 SLARRAPLMFGPGLR-DPPPPRPAPPRPGEE--PGNRHPPPPAARTHPGSCRARCPSPAA 78
S+ RAP+ P L D P PP PG+ P PPPP PG P
Sbjct: 566 SVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLP 625
Query: 79 GG--------LRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPG--RDALR 128
GG L G T P EG P LPG A P P + R
Sbjct: 626 GGTAISPPPPLSGDATIPP-PPPLPEGVGIPSPS-------SLPGGTAIPPPPPLPGSAR 677
Query: 129 LPPPPPP-------PPERPRL--------PPAGLAGGPADSAPPSPAPAPRSRPAPRPG 172
+PPPPPP PP P L PP L GGP PP P P P P PG
Sbjct: 678 IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPG-IPPPPPFPGGPGIPPPPPG 735
Score = 55.1 bits (131), Expect = 3e-08
Identities = 50/147 (34%), Positives = 57/147 (38%), Gaps = 24/147 (16%)
Query: 27 APLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWT 86
A + P + P PAPP PG+ G PPPPA PG P P P
Sbjct: 559 AAITVPPSVPSRAPVPPAPPLPGDS-GTIIPPPPA----PGDSTTPPPPPPPPP---PPP 610
Query: 87 AAPGRQRADEGAAAARPERQRVWARRLPGSAA-APAPGRDALRLPPPPPPPPERPRLP-P 144
PG G + P LPG A +P P PPPPP PE +P P
Sbjct: 611 PLPG------GVCISSPPS-------LPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSP 657
Query: 145 AGLAGGPADSAPPSPAPAPRSRPAPRP 171
+ L GG A PP P P P P P
Sbjct: 658 SSLPGGTA-IPPPPPLPGSARIPPPPP 683
Score = 45.1 bits (105), Expect = 3e-05
Identities = 30/72 (41%), Positives = 32/72 (44%), Gaps = 10/72 (13%)
Query: 112 RLPGSAAAPAPGRDALRLPPPP--------PPPPERPRLPPAGLAGGPADSAPPS-PAPA 162
R P A P PG +PPPP PPPP P PP L GG S+PPS P
Sbjct: 570 RAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPP-PPPPLPGGVCISSPPSLPGGT 628
Query: 163 PRSRPAPRPGHA 174
S P P G A
Sbjct: 629 AISPPPPLSGDA 640
Score = 44.3 bits (103), Expect = 5e-05
Identities = 46/150 (30%), Positives = 50/150 (33%), Gaps = 27/150 (18%)
Query: 28 PLMFGPGLRDPPPPRPAP---PRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRG- 83
P + G PPPP P P P PG PPP PGS R P P G G
Sbjct: 634 PPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPL--PGSARIPPPPPPLPGSAGI 691
Query: 84 --PWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAP----GRDALRLPPPPPPPP 137
P PG + G P LPG P P G + PPPPP
Sbjct: 692 PPPPPPLPG----EAGMPPPPPP--------LPGGPGIPPPPPFPGGPGI---PPPPPGM 736
Query: 138 ERPRLPPAGLAGGPADSAPPSPAPAPRSRP 167
P PP G A P P +P
Sbjct: 737 GMPPPPPFGFGVPAAPVLPFGLTPKKLYKP 766
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 60.8 bits (146), Expect = 6e-10
Identities = 60/179 (33%), Positives = 65/179 (36%), Gaps = 37/179 (20%)
Query: 22 SLARRAPLMFGPGLR-DPPPPRPAPPRPGEE--PGNRHPPPPAARTHPGSCRARCPSPAA 78
S+ RAP+ P L D P PP PG+ P PPPP PG P
Sbjct: 575 SVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLP 634
Query: 79 GG--------LRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPG--RDALR 128
GG L G T P EG P LPG A P P + R
Sbjct: 635 GGTAISPPPPLSGDATIPP-PPPLPEGVGIPSPS-------SLPGGTAIPPPPPLPGSAR 686
Query: 129 LPPPPPP-------PPERPRL--------PPAGLAGGPADSAPPSPAPAPRSRPAPRPG 172
+PPPPPP PP P L PP L GGP PP P P P P PG
Sbjct: 687 IPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPG-IPPPPPFPGGPGIPPPPPG 744
Score = 55.1 bits (131), Expect = 3e-08
Identities = 50/147 (34%), Positives = 57/147 (38%), Gaps = 24/147 (16%)
Query: 27 APLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWT 86
A + P + P PAPP PG+ G PPPPA PG P P P
Sbjct: 568 AAITVPPSVPSRAPVPPAPPLPGDS-GTIIPPPPA----PGDSTTPPPPPPPPP---PPP 619
Query: 87 AAPGRQRADEGAAAARPERQRVWARRLPGSAA-APAPGRDALRLPPPPPPPPERPRLP-P 144
PG G + P LPG A +P P PPPPP PE +P P
Sbjct: 620 PLPG------GVCISSPPS-------LPGGTAISPPPPLSGDATIPPPPPLPEGVGIPSP 666
Query: 145 AGLAGGPADSAPPSPAPAPRSRPAPRP 171
+ L GG A PP P P P P P
Sbjct: 667 SSLPGGTA-IPPPPPLPGSARIPPPPP 692
Score = 45.1 bits (105), Expect = 3e-05
Identities = 30/72 (41%), Positives = 32/72 (44%), Gaps = 10/72 (13%)
Query: 112 RLPGSAAAPAPGRDALRLPPPP--------PPPPERPRLPPAGLAGGPADSAPPS-PAPA 162
R P A P PG +PPPP PPPP P PP L GG S+PPS P
Sbjct: 579 RAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPP-PPPPLPGGVCISSPPSLPGGT 637
Query: 163 PRSRPAPRPGHA 174
S P P G A
Sbjct: 638 AISPPPPLSGDA 649
Score = 44.3 bits (103), Expect = 5e-05
Identities = 46/150 (30%), Positives = 50/150 (33%), Gaps = 27/150 (18%)
Query: 28 PLMFGPGLRDPPPPRPAP---PRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRG- 83
P + G PPPP P P P PG PPP PGS R P P G G
Sbjct: 643 PPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPL--PGSARIPPPPPPLPGSAGI 700
Query: 84 --PWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAP----GRDALRLPPPPPPPP 137
P PG + G P LPG P P G + PPPPP
Sbjct: 701 PPPPPPLPG----EAGMPPPPPP--------LPGGPGIPPPPPFPGGPGI---PPPPPGM 745
Query: 138 ERPRLPPAGLAGGPADSAPPSPAPAPRSRP 167
P PP G A P P +P
Sbjct: 746 GMPPPPPFGFGVPAAPVLPFGLTPKKLYKP 775
>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
sapiens]
Length = 247
Score = 60.8 bits (146), Expect = 6e-10
Identities = 57/193 (29%), Positives = 72/193 (37%), Gaps = 43/193 (22%)
Query: 2 PNKASGR--RQGRARGRPHSQVSLARRAPLMFGPGLRDPPPPRPAPPRPGEEPGN---RH 56
P K GR + G P R P G + PPP P RP + GN R
Sbjct: 75 PGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRP 134
Query: 57 PPPPAARTHP---GSCRARCPSPAAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRL 113
PPPP P G +++ P P G GP + R+ AR
Sbjct: 135 PPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRS---------------ARSP 179
Query: 114 PGSAAAPAPGRDALRL--PPPP-----PPP----PERPRLPPAGLAGGPADSAPPSPAPA 162
PG P P ++ + PPPP PPP P++P+ PPAG P P P
Sbjct: 180 PGKPQGP-PQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAPPAG--------KPQGPPPP 230
Query: 163 PRSRPAPRPGHAQ 175
P+ PRP Q
Sbjct: 231 PQGGRPPRPAQGQ 243
Score = 53.9 bits (128), Expect = 7e-08
Identities = 45/143 (31%), Positives = 55/143 (38%), Gaps = 25/143 (17%)
Query: 36 RDPPPP---RPAPPRPGEEPGNRHPPP--PAARTHPGSCRARCPSPAAGGLRGPWTAAPG 90
R PPPP + PP+ G + PPP P R G +++ P P G P G
Sbjct: 49 RPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERP-PPQGG 107
Query: 91 RQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPERPRLPPAGLAGG 150
Q +PER P G + PPPPP PERP PP GG
Sbjct: 108 NQSQGTPPPPGKPERP-------------PPQGGNQSHRPPPPPGKPERP--PP---QGG 149
Query: 151 PADSAPPSPAPAPRSRPAPRPGH 173
PP P P P P+ G+
Sbjct: 150 NQSQGPP-PHPGKPEGPPPQEGN 171
Score = 38.1 bits (87), Expect = 0.004
Identities = 19/44 (43%), Positives = 23/44 (52%), Gaps = 3/44 (6%)
Query: 130 PPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRPAPRPGH 173
P PPPPP +P+ PP GG PP P P RP P+ G+
Sbjct: 47 PQRPPPPPGKPQGPPP--QGGNQSQGPPPPPGKPEGRP-PQGGN 87
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 60.5 bits (145), Expect = 7e-10
Identities = 60/176 (34%), Positives = 66/176 (37%), Gaps = 41/176 (23%)
Query: 5 ASGRRQGRARGRPHSQVSLARRAPLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPAART 64
AS ++Q + P SQ+ +AP M GP PPP P P PG G PPP A
Sbjct: 386 ASSQQQAPPQSVPPSQI----QAPPMPGPPPLGPPPAPPLRP-PGPPTGLPPGPPPGA-- 438
Query: 65 HPGSCRARCPSPAAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGR 124
P R P GLRGP + G RP PG P PG
Sbjct: 439 -PPFLRP----PGMPGLRGPLP-----RLLPPGPPPGRP----------PGPPPGPPPG- 477
Query: 125 DALRLPPPPPPPPERPRLPPAGLAGGPADSA---------PPSPAPAPRSRPAPRP 171
LPP PPP PRLPP G P P PAP PAP P
Sbjct: 478 ----LPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLP 529
Score = 58.9 bits (141), Expect = 2e-09
Identities = 51/156 (32%), Positives = 54/156 (34%), Gaps = 36/156 (23%)
Query: 19 SQVSLARRAPLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAA 78
S S ++AP P + PP P PP G PPPA P P P
Sbjct: 384 STASSQQQAPPQSVPPSQIQAPPMPGPPPLG--------PPPAPPLRP-------PGPPT 428
Query: 79 GGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPE 138
G GP AP R PG P L PPP PP
Sbjct: 429 GLPPGPPPGAPPFLRP-------------------PGMPGLRGPLPRLLPPGPPPGRPPG 469
Query: 139 RPRLPPAGLAGGPADSAPPS--PAPAPRSRPAPRPG 172
P PP GL GP PP P PAP P PRPG
Sbjct: 470 PPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPG 505
Score = 26.9 bits (58), Expect = 9.0
Identities = 33/115 (28%), Positives = 42/115 (36%), Gaps = 26/115 (22%)
Query: 33 PGLRDPP--------PPRPAPPRPGEEPGNRHPPP-----PAA-----------RTHPGS 68
PG+ PP PP PP P PG PP P A T S
Sbjct: 504 PGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATATIS 563
Query: 69 CRARCPSPAAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPG 123
+ + +P A R TA R R + A A P+R+ +P + AAP G
Sbjct: 564 AKPQITNPKAEITRFVPTAL--RVRRENKGATAAPQRKSEDDSAVPLAKAAPKSG 616
>gi|39812378 RAN binding protein 9 [Homo sapiens]
Length = 729
Score = 59.3 bits (142), Expect = 2e-09
Identities = 49/142 (34%), Positives = 55/142 (38%), Gaps = 20/142 (14%)
Query: 38 PPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADEG 97
PPPP PP+ ++ PPPPAA P+P A +PG EG
Sbjct: 5 PPPP---PPQQQQQQQQLSPPPPAALAPVSG--VVLPAPPAVSAGSSPAGSPGGGAGGEG 59
Query: 98 AAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPERPRLP------PAGLAG-- 149
AA P + AAP P PPPPPPPP P P GLA
Sbjct: 60 LGAAAAALLLHPPPPPPPATAAPPP-------PPPPPPPPASAAAPASGPPAPPGLAAGP 112
Query: 150 GPADSAPPSPAPAPRSRPAPRP 171
GPA AP A S AP P
Sbjct: 113 GPAGGAPTPALVAGSSAAAPFP 134
Score = 37.4 bits (85), Expect = 0.007
Identities = 27/67 (40%), Positives = 29/67 (43%), Gaps = 4/67 (5%)
Query: 35 LRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRA 94
L PPPP PA P P PPPPA+ P S P AAG GP AP
Sbjct: 69 LHPPPPPPPATAAPPPPP--PPPPPPASAAAPASGPPAPPGLAAG--PGPAGGAPTPALV 124
Query: 95 DEGAAAA 101
+AAA
Sbjct: 125 AGSSAAA 131
Score = 35.4 bits (80), Expect = 0.025
Identities = 22/59 (37%), Positives = 25/59 (42%), Gaps = 5/59 (8%)
Query: 33 PGLRDPPPPRPAPPRPGE--EPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAP 89
P PPPP P PP P P + P PP PG P+PA + G AAP
Sbjct: 77 PATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPA-GGAPTPAL--VAGSSAAAP 132
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 58.9 bits (141), Expect = 2e-09
Identities = 43/134 (32%), Positives = 47/134 (35%), Gaps = 27/134 (20%)
Query: 38 PPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADEG 97
PPP P PG +PG PPPA P P P G P T P
Sbjct: 300 PPPAPPLGSPPGPKPG--FAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPP-------- 349
Query: 98 AAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPERPRLPPAGLAGGPADSAPP 157
P + P A PPPPPP + P LPP L+ P APP
Sbjct: 350 ----------------PSPPSFPPHPDFAAPPPPPPPPAADYPTLPPPPLS-QPTGGAPP 392
Query: 158 SPAPAPRSRPAPRP 171
P P P P P P
Sbjct: 393 PPPPPPPPGPPPPP 406
Score = 52.4 bits (124), Expect = 2e-07
Identities = 44/134 (32%), Positives = 49/134 (36%), Gaps = 20/134 (14%)
Query: 33 PGLRDPP-PPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGR 91
PG PP PP P PP G P PPPP PG+ PSP + + A P
Sbjct: 314 PGFAPPPAPPPPPPPMIGIPP----PPPPVGFGSPGTPPP--PSPPSFPPHPDFAAPPPP 367
Query: 92 QRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPERPRLPPAGLAGGP 151
P P + P G PPPPPPPP P P G G P
Sbjct: 368 PPPPAADYPTLP----------PPPLSQPTGGAPP---PPPPPPPPGPPPPPFTGADGQP 414
Query: 152 ADSAPPSPAPAPRS 165
A P S P+S
Sbjct: 415 AIPPPLSDTTKPKS 428
Score = 37.7 bits (86), Expect = 0.005
Identities = 26/66 (39%), Positives = 33/66 (50%), Gaps = 9/66 (13%)
Query: 116 SAAAPAPGRDALRLPPPPPP---PPERPRLPPAGLAGGPADS----APPSPAPAPRSRPA 168
SA++P+P LPPPP P + R +GLAG S + P PAP S P
Sbjct: 254 SASSPSPSFSEDNLPPPPAEFSYPVDNQR--GSGLAGPKRSSVVSPSHPPPAPPLGSPPG 311
Query: 169 PRPGHA 174
P+PG A
Sbjct: 312 PKPGFA 317
Score = 36.6 bits (83), Expect = 0.011
Identities = 41/149 (27%), Positives = 53/149 (35%), Gaps = 42/149 (28%)
Query: 38 PPPPRP---APPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRA 94
PPPP+ + P P N PPPPA ++P + GL GP +R+
Sbjct: 247 PPPPQSDSASSPSPSFSEDNL-PPPPAEFSYP------VDNQRGSGLAGP-------KRS 292
Query: 95 DEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPERPRLPPAGLA------ 148
+ + P + GS P PG PPP P P P G+
Sbjct: 293 SVVSPSHPPPAPPL------GSPPGPKPGF-------APPPAPPPPPPPMIGIPPPPPPV 339
Query: 149 --GGPADSAPPSPAPAPR----SRPAPRP 171
G P PPSP P + P P P
Sbjct: 340 GFGSPGTPPPPSPPSFPPHPDFAAPPPPP 368
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 58.5 bits (140), Expect = 3e-09
Identities = 63/177 (35%), Positives = 71/177 (40%), Gaps = 39/177 (22%)
Query: 16 RPHSQVSLARRAPLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSC------ 69
+P +LA RA GPG P P P P PG+ G P AA+T GS
Sbjct: 159 KPAGPAALAARA----GPGPGPGPGPGPGPG-PGKPAG-----PGAAQTLNGSAALLNSH 208
Query: 70 RARCPSPA------AGGLRGPWTAAPGR--QRADEGAAAARPERQRVWARRLPGSAAAPA 121
A P+ + A L P AAPG Q AAA P A P AAPA
Sbjct: 209 HAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPP------APAAPSPPAAPA 262
Query: 122 PGRDALRLPPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPR-------SRPAPRP 171
P A PPPPP P R P G GP +AP P PA + PAP P
Sbjct: 263 PAAPAAAPPPPPPAPATLAR--PPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAP 317
Score = 54.7 bits (130), Expect = 4e-08
Identities = 52/149 (34%), Positives = 61/149 (40%), Gaps = 29/149 (19%)
Query: 38 PPPPRPAPPRPGEEPGNRHP----------PPPAARTHPGSCRAR-CPSPAAG------G 80
PPPP PAP PG HP PPPAA + GS A P+PAAG G
Sbjct: 270 PPPPPPAPATLARPPG--HPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSG 327
Query: 81 LRGPWTA----APG-RQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALR--LPPP- 132
GP A APG + + + A P + A P S AA ++ LP P
Sbjct: 328 QPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPA 387
Query: 133 --PPPPPERPRLPPAGLAGGPADSAPPSP 159
PPP P P P G AG S +P
Sbjct: 388 AVPPPAPGTPTGLPKGAAGAVTQSLSRTP 416
Score = 53.9 bits (128), Expect = 7e-08
Identities = 63/226 (27%), Positives = 69/226 (30%), Gaps = 71/226 (31%)
Query: 15 GRPHSQVSLARRAPLMFGPGLRDPPPP------------RPAPPRPGEEPGNRHPPPPAA 62
G P AP PG PPP RP PP P P PPAA
Sbjct: 65 GSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAA 124
Query: 63 RTHP---GSCRARCPSPAAGGL-RGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAA 118
+ P GS + P PAA + GP A G A AA R PG
Sbjct: 125 KLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAG--PAKPAGPAALAARAGPGPGPGPGPGP 182
Query: 119 APAPGRDA-----------------------------------LRLPPP----------- 132
P PG+ A L LP P
Sbjct: 183 GPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPP 242
Query: 133 -----PPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRPAPRPGH 173
PP P P P A PA +APP P PAP + P PGH
Sbjct: 243 FVGAAAPPAPAAPSPPAAPAPAAPA-AAPPPPPPAPATLARP-PGH 286
Score = 50.1 bits (118), Expect = 1e-06
Identities = 47/141 (33%), Positives = 52/141 (36%), Gaps = 27/141 (19%)
Query: 43 PAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADEG----A 98
PA P G PG PPPA R PG GG + P +P R G A
Sbjct: 75 PAAPAEGA-PGAAPEPPPAGRARPGG----------GGPQRPGPPSPRRPLVPAGPAPPA 123
Query: 99 AAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPERPRLP--PAGLAGGPADSAP 156
A RP + GSA + AP A + P P P P P PA LA
Sbjct: 124 AKLRPPPE--------GSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPG 175
Query: 157 PSPAPAPRSRPA--PRPGHAQ 175
P P P P P PG AQ
Sbjct: 176 PGPGPGPGPGPGKPAGPGAAQ 196
Score = 45.1 bits (105), Expect = 3e-05
Identities = 56/176 (31%), Positives = 64/176 (36%), Gaps = 38/176 (21%)
Query: 28 PLMFGPGLRDPP------PPRPAPPRPGEEPGNR------HPPPPAART------HPG-- 67
P G ++ PP PP PA P P P PPPPA T HP
Sbjct: 231 PAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGP 290
Query: 68 -SCRARCPSPAAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPG-SAAAPAPGRD 125
+ P PAA G AAP A G A V + PG +AAAPAPG
Sbjct: 291 PTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAG-------VSGQPGPGAAAAAPAPGVK 343
Query: 126 A---LRLPPPPPPPPER-----PRLPPAGLAGGPA-DSAPPSPAPAPRSRPAPRPG 172
A R+ PP + P A + GP A PSPA P P G
Sbjct: 344 AESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTG 399
>gi|60460889 Myb protein P42POP [Homo sapiens]
Length = 399
Score = 58.5 bits (140), Expect = 3e-09
Identities = 50/163 (30%), Positives = 57/163 (34%), Gaps = 33/163 (20%)
Query: 33 PGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRG-PWTAAPGR 91
P L PPP P P P PPP + + P R A +R T G
Sbjct: 225 PPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGL 284
Query: 92 QRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPERPRLPP------- 144
+ E +A P LPG+ P PPPPPPPP RP LPP
Sbjct: 285 AKLSEALSALLP--------LLPGT---PVDSLPPPLPPPPPPPPPPRPVLPPPAPKVEI 333
Query: 145 --------------AGLAGGPADSAPPSPAPAPRSRPAPRPGH 173
A +A AP S APR PAP P H
Sbjct: 334 TPEPVSVVAAVVDGAVVAARGVIIAPRSEEGAPRPPPAPLPPH 376
Score = 44.3 bits (103), Expect = 5e-05
Identities = 44/145 (30%), Positives = 54/145 (37%), Gaps = 19/145 (13%)
Query: 30 MFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPA-------ARTHPGSCRARCPSPAAGGLR 82
+ GPG+ P A P P ++ PPP A + RA + + G
Sbjct: 119 ILGPGVAAPGAGAGAEEPPAA-PSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSS 177
Query: 83 GPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPERPRL 142
P A EG ER+ P SA P L L PPPP PP P
Sbjct: 178 SPEPWARPSCTPQEGGCPRPKERESP-----PPSALQPVQ-LPRLALSPPPPAPPLPPPP 231
Query: 143 PPAGLAGGPADSAPPSPAPAPRSRP 167
P A +A +PPSP P PR P
Sbjct: 232 PLAQVA-----PSPPSPPPPPRPPP 251
Score = 36.6 bits (83), Expect = 0.011
Identities = 39/132 (29%), Positives = 46/132 (34%), Gaps = 33/132 (25%)
Query: 9 RQGRARGRPHSQVSLARRAPLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGS 68
RQG A+ +L+ PL+ G + PPP P PP P PPPP
Sbjct: 281 RQGLAK----LSEALSALLPLLPGTPVDSLPPPLPPPPPP--------PPPP-------- 320
Query: 69 CRARCPSPAAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALR 128
R P PA P + D AAR G AP A R
Sbjct: 321 -RPVLPPPAPKVEITPEPVSVVAAVVDGAVVAAR------------GVIIAPRSEEGAPR 367
Query: 129 LPPPPPPPPERP 140
PP P PP + P
Sbjct: 368 PPPAPLPPHDSP 379
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 58.5 bits (140), Expect = 3e-09
Identities = 47/154 (30%), Positives = 52/154 (33%), Gaps = 13/154 (8%)
Query: 14 RGRPHSQVSLARRAPLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARC 73
R S L P P DP AP PG P PPPP P A
Sbjct: 740 RAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASP 799
Query: 74 PSPAAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPP 133
P+A G ++PG + D G P PG AA G R PP
Sbjct: 800 DPPSAVASPGSGLSSPGPKPGDSGYETETPFSPE---GAFPGGGAAEEEGVPRPR-APPE 855
Query: 134 PPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRP 167
PP P PR PP P P P PR +P
Sbjct: 856 PPDPGAPRPPP---------DPGPLPLPGPREKP 880
Score = 48.1 bits (113), Expect = 4e-06
Identities = 44/143 (30%), Positives = 51/143 (35%), Gaps = 28/143 (19%)
Query: 49 GEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPG-----------RQRADEG 97
G P R P P + G+C C G W P RA+ G
Sbjct: 687 GGGPSRRGPLPCPLCSREGACS--CLPLERGDAVAGWGGHPALGCPHPPEDDSSLRAERG 744
Query: 98 AAAARPERQRVWARR-----LPGSAAAPAPGRDALRLPPPPPPPPERPRLPPAGLAGGPA 152
+ A P A L G+AA PGR PPPPPPPP P P A
Sbjct: 745 SLADLPMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADP-------AA 797
Query: 153 DSAPPSPAPAP---RSRPAPRPG 172
PPS +P S P P+PG
Sbjct: 798 SPDPPSAVASPGSGLSSPGPKPG 820
Score = 47.0 bits (110), Expect = 8e-06
Identities = 47/139 (33%), Positives = 51/139 (36%), Gaps = 21/139 (15%)
Query: 36 RDPPPPRPAPPRPGEE--PGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQR 93
R P P R G E PG P P PG+ R +P GG APG R
Sbjct: 1083 RAPAPSAVVSSRNGGETAPGPLGPAPKNGTLEPGTERR---APETGGA----PRAPGAGR 1135
Query: 94 ADEGAAAARPERQRVWARRLPGSAA-APAPGRDALRLPPPPPPPPERPRLPPAGLAGGPA 152
D G+ P PGS A A D R PPPPP P P P L
Sbjct: 1136 LDLGSGGRAPVGTGTAPGGGPGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRL----- 1190
Query: 153 DSAPPSPAPAPRSRPAPRP 171
PAP PR+RP P
Sbjct: 1191 -----EPAP-PRARPEVAP 1203
Score = 46.2 bits (108), Expect = 1e-05
Identities = 45/138 (32%), Positives = 52/138 (37%), Gaps = 18/138 (13%)
Query: 36 RDPPPPRPAPPRPGEEPGNRHPPPPAART------HPGSCRARCPSPAA----GGLRGPW 85
R PPP P PP P +P P PP AR PG+ +R A G P
Sbjct: 1171 RPQPPPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRAGGDTALSGDGDPPKPE 1230
Query: 86 TAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPERP--RLP 143
P R + +++ AR S A P L L P P P P RP
Sbjct: 1231 RKGPEMPRLFLDLGPPQGNSEQIKARLSRLSLALP-----PLTLTPFPGPGPRRPPWEGA 1285
Query: 144 PAGLAGGPADSA-PPSPA 160
AG AGG A A P PA
Sbjct: 1286 DAGAAGGEAGGAGAPGPA 1303
Score = 34.3 bits (77), Expect = 0.057
Identities = 29/108 (26%), Positives = 34/108 (31%), Gaps = 17/108 (15%)
Query: 40 PPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADEGAA 99
PPRP PP PPPP P +P G L P+ G AD
Sbjct: 445 PPRPPPP----------PPPPRDGPFPWPWPPAHSAPRPGTLSSPFPLLDGFPGADPDDV 494
Query: 100 AARPERQR------VWARRLPGSA-AAPAPGRDALRLPPPPPPPPERP 140
E R +W + G+ AP PP P P P
Sbjct: 495 LTVTESSRGLNLECLWEKARRGAGRGGGAPAWQPASAPPAPHANPSNP 542
Score = 33.5 bits (75), Expect = 0.097
Identities = 18/43 (41%), Positives = 19/43 (44%), Gaps = 13/43 (30%)
Query: 130 PPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRPAPRPG 172
PP PPPPP PR P P P P + APRPG
Sbjct: 445 PPRPPPPPPPPR-------------DGPFPWPWPPAHSAPRPG 474
Score = 30.8 bits (68), Expect = 0.63
Identities = 58/217 (26%), Positives = 65/217 (29%), Gaps = 86/217 (39%)
Query: 32 GPGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCR-------ARCPSPAAGGLRGP 84
GPG R PP G E G P PA A P AAG RGP
Sbjct: 1274 GPGPRRPPWEGADAGAAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGP-RGP 1332
Query: 85 WTAAPGRQRA--------DEGAAAARP-------------------ERQR---------- 107
GR RA A AARP ER+R
Sbjct: 1333 -----GRARAAPVPVVVSSADADAARPLRGLLKSPRGADEPEDSELERKRKMVSFHGDVT 1387
Query: 108 --VWARRLPG---SAAAPAPGRDALRLPPPPPPPP------------------------E 138
++ + P S AP G PP PP PP +
Sbjct: 1388 VYLFDQETPTNELSVQAPPEGDTDPSTPPAPPTPPHPATPGDGFPSNDSGFGGSFEWAED 1447
Query: 139 RPRLPPAG-------LAGGPADSAPPSPAPAPRSRPA 168
P LPP G + PA P PA AP +RPA
Sbjct: 1448 FPLLPPPGPPLCFSRFSVSPALETPGPPARAPDARPA 1484
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 58.2 bits (139), Expect = 4e-09
Identities = 46/144 (31%), Positives = 55/144 (38%), Gaps = 17/144 (11%)
Query: 38 PPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGR------ 91
PPPPRP P P R PPPP+ R+ P S +A P G P R
Sbjct: 1103 PPPPRPVAPPTRPAPPQR-PPPPSGRSQP-SPQAGLAGPGPAGYSTARPTIPPRAGVISA 1160
Query: 92 --QRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPP--PPPPERPRLPPAGL 147
A A PE Q + GS P P + PP PPP +R + P +
Sbjct: 1161 PQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPV 1220
Query: 148 A-----GGPADSAPPSPAPAPRSR 166
A GP + P P PRSR
Sbjct: 1221 AAPMPQSGPQPNLETPPQPPPRSR 1244
Score = 42.4 bits (98), Expect = 2e-04
Identities = 39/135 (28%), Positives = 50/135 (37%), Gaps = 22/135 (16%)
Query: 43 PAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADEGAAAAR 102
P +P G P + RT P C SP GP + P R
Sbjct: 1022 PQHLQPSSSSGLGTSPSSSPRTSP------CQSPTIS--EGPVPSLP-----------IR 1062
Query: 103 PERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPERP-RLPPAGLAGGPADSAPPS--P 159
P R P + ++P + A LP P P P R PP P APP P
Sbjct: 1063 PSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPP 1122
Query: 160 APAPRSRPAPRPGHA 174
P+ RS+P+P+ G A
Sbjct: 1123 PPSGRSQPSPQAGLA 1137
Score = 40.4 bits (93), Expect = 8e-04
Identities = 45/159 (28%), Positives = 60/159 (37%), Gaps = 30/159 (18%)
Query: 19 SQVSLARRAPLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAA 78
S S R +P P + + P P P RP P +R P PP+A++ P + P P
Sbjct: 1036 SPSSSPRTSPCQ-SPTISEGPVPS-LPIRPSRAP-SRTPGPPSAQSSPIDAQPATPLPQ- 1091
Query: 79 GGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPE 138
+ Q + +R P P R A PPPP
Sbjct: 1092 -----------------------KDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRS 1128
Query: 139 RPRLPPAGLAG-GPADSAPPSPAPAPRSRPAPRP-GHAQ 175
+P P AGLAG GPA + P PR+ P HA+
Sbjct: 1129 QPS-PQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHAR 1166
>gi|19924099 synapsin I isoform Ia [Homo sapiens]
Length = 705
Score = 57.4 bits (137), Expect = 6e-09
Identities = 46/161 (28%), Positives = 57/161 (35%), Gaps = 20/161 (12%)
Query: 32 GPGLRDPPPPRPAPPRPGEEPGNRHP-----PPPAARTHPGSCRARCPSPAAGGLRGPWT 86
GP + PPP+ PP+PG P + P PPP + H SP L P +
Sbjct: 454 GPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTS 513
Query: 87 A--APGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPP---------PP 135
A P Q A R R P +A PA + PP P
Sbjct: 514 APQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPA 573
Query: 136 PPERPRLPPAGLAGGPADSAPPSPA----PAPRSRPAPRPG 172
PP+ PP G PP PA A ++ P PR G
Sbjct: 574 PPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTG 614
Score = 46.2 bits (108), Expect = 1e-05
Identities = 49/180 (27%), Positives = 64/180 (35%), Gaps = 28/180 (15%)
Query: 1 MPNKASGRRQGRARGRPHSQVSLARRAPLMFGPGLRDPPPPRP-APPRPGEEPGNRHPPP 59
+P+ S +Q ++ P +Q + P+ GPG PP RP A P P + G PP
Sbjct: 508 LPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGA--PPAARPPASPSPQRQAG----PP 561
Query: 60 PAAR----THPGSCRARCPSPAAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPG 115
A R + P +A P +GP PG A P RQ
Sbjct: 562 QATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPG---------PAGPTRQ--------A 604
Query: 116 SAAAPAPGRDALRLPPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRPAPRPGHAQ 175
S A P P P P P P LA P+ PP A P P+ +Q
Sbjct: 605 SQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQ 664
Score = 37.7 bits (86), Expect = 0.005
Identities = 34/132 (25%), Positives = 48/132 (36%), Gaps = 15/132 (11%)
Query: 39 PPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADEGA 98
P R +P P + PPP PG P P +GP + +
Sbjct: 443 PLGRQTSQQPAGPPAQQRPPPQGGPPQPG------PGPQR---QGPPLQQRPPPQGQQHL 493
Query: 99 AAARPERQRVWARRLPGSAAAP-APGRDALRLPPPPPPPPERPRLPPAGLAGGPADSAPP 157
+ P +RLP +AP P A PP R P AG G P + PP
Sbjct: 494 SGLGPPAGSPLPQRLPSPTSAPQQPASQA----APPTQGQGRQSRPVAGGPGAPPAARPP 549
Query: 158 SPAPAPRSRPAP 169
+ +P+P+ + P
Sbjct: 550 A-SPSPQRQAGP 560
Score = 30.8 bits (68), Expect = 0.63
Identities = 19/47 (40%), Positives = 22/47 (46%), Gaps = 3/47 (6%)
Query: 127 LRLPPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRP-APRPG 172
L+ P PPPPPP P G +A S AP + P AP PG
Sbjct: 25 LQRPQPPPPPPGAH--SPGATPGPGTATAERSSGVAPAASPAAPSPG 69
Score = 28.9 bits (63), Expect = 2.4
Identities = 20/72 (27%), Positives = 27/72 (37%), Gaps = 5/72 (6%)
Query: 35 LRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGS-----CRARCPSPAAGGLRGPWTAAP 89
+ D P+P PP PG P P A S PSP + G G +++
Sbjct: 22 MTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGGFFSSLS 81
Query: 90 GRQRADEGAAAA 101
+ AAAA
Sbjct: 82 NAVKQTTAAAAA 93
>gi|19924097 synapsin I isoform Ib [Homo sapiens]
Length = 669
Score = 57.4 bits (137), Expect = 6e-09
Identities = 46/161 (28%), Positives = 57/161 (35%), Gaps = 20/161 (12%)
Query: 32 GPGLRDPPPPRPAPPRPGEEPGNRHP-----PPPAARTHPGSCRARCPSPAAGGLRGPWT 86
GP + PPP+ PP+PG P + P PPP + H SP L P +
Sbjct: 454 GPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTS 513
Query: 87 A--APGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPP---------PP 135
A P Q A R R P +A PA + PP P
Sbjct: 514 APQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTSVSGPA 573
Query: 136 PPERPRLPPAGLAGGPADSAPPSPA----PAPRSRPAPRPG 172
PP+ PP G PP PA A ++ P PR G
Sbjct: 574 PPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTG 614
Score = 45.8 bits (107), Expect = 2e-05
Identities = 51/184 (27%), Positives = 65/184 (35%), Gaps = 32/184 (17%)
Query: 1 MPNKASGRRQGRARGRPHSQVSLARRAPLMFGPGLRDPPPPRP-APPRPGEEPGNRHPPP 59
+P+ S +Q ++ P +Q + P+ GPG PP RP A P P + G PP
Sbjct: 508 LPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGA--PPAARPPASPSPQRQAG----PP 561
Query: 60 PAAR----THPGSCRARCPSPAAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPG 115
A R + P +A P +GP PG A P RQ
Sbjct: 562 QATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPG---------PAGPTRQ--------A 604
Query: 116 SAAAPAPGRDALRLPPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRPAPR----P 171
S A P P P P P P LA P+ PP A P P+ P
Sbjct: 605 SQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASP 664
Query: 172 GHAQ 175
AQ
Sbjct: 665 AQAQ 668
Score = 37.7 bits (86), Expect = 0.005
Identities = 34/132 (25%), Positives = 48/132 (36%), Gaps = 15/132 (11%)
Query: 39 PPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADEGA 98
P R +P P + PPP PG P P +GP + +
Sbjct: 443 PLGRQTSQQPAGPPAQQRPPPQGGPPQPG------PGPQR---QGPPLQQRPPPQGQQHL 493
Query: 99 AAARPERQRVWARRLPGSAAAP-APGRDALRLPPPPPPPPERPRLPPAGLAGGPADSAPP 157
+ P +RLP +AP P A PP R P AG G P + PP
Sbjct: 494 SGLGPPAGSPLPQRLPSPTSAPQQPASQA----APPTQGQGRQSRPVAGGPGAPPAARPP 549
Query: 158 SPAPAPRSRPAP 169
+ +P+P+ + P
Sbjct: 550 A-SPSPQRQAGP 560
Score = 30.8 bits (68), Expect = 0.63
Identities = 19/47 (40%), Positives = 22/47 (46%), Gaps = 3/47 (6%)
Query: 127 LRLPPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRP-APRPG 172
L+ P PPPPPP P G +A S AP + P AP PG
Sbjct: 25 LQRPQPPPPPPGAH--SPGATPGPGTATAERSSGVAPAASPAAPSPG 69
Score = 28.9 bits (63), Expect = 2.4
Identities = 20/72 (27%), Positives = 27/72 (37%), Gaps = 5/72 (6%)
Query: 35 LRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGS-----CRARCPSPAAGGLRGPWTAAP 89
+ D P+P PP PG P P A S PSP + G G +++
Sbjct: 22 MTDLQRPQPPPPPPGAHSPGATPGPGTATAERSSGVAPAASPAAPSPGSSGGGGFFSSLS 81
Query: 90 GRQRADEGAAAA 101
+ AAAA
Sbjct: 82 NAVKQTTAAAAA 93
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 57.0 bits (136), Expect = 8e-09
Identities = 57/186 (30%), Positives = 69/186 (37%), Gaps = 34/186 (18%)
Query: 16 RPHSQVSLARRAPLMFGPGLRDPPPP----RPAPPRP--GEEPGNRHPPPPAA-RTHPGS 68
+P S S R P+ PG R PP R PPRP G +P + PP P+ R S
Sbjct: 139 KPFSPPSGPGRFPVP-SPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSS 197
Query: 69 CRARCPSPAAGGLRGPWTAA-----PGRQRADEGAAAARPE---RQRVWARRLPGSAAAP 120
R P GG R P PG + G + R ++ R P P
Sbjct: 198 PHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPP---LPP 254
Query: 121 APGRDALRLPPPPPPP---------------PERPRLPPAGLAGGPADSAPPSPAPAPRS 165
P R PPPPPPP P + PP P+ S+ P P P S
Sbjct: 255 TPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPS 314
Query: 166 RPAPRP 171
RP P P
Sbjct: 315 RPGPPP 320
Score = 52.4 bits (124), Expect = 2e-07
Identities = 53/174 (30%), Positives = 66/174 (37%), Gaps = 21/174 (12%)
Query: 3 NKASGRRQGRARGRPHSQVS-LARRAPLMFGPGL----RDPPPPRPAPPRPGEEPGNRHP 57
N+ + G R P S S + R PL P + PPPP P RP P
Sbjct: 225 NRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPP 284
Query: 58 PPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADE--GAAAARPERQRVWARRLPG 115
PPP P P P+A P P R +++ E R+ R L
Sbjct: 285 PPPQNNKPPVPST---PRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSL 341
Query: 116 SAAAP---APGRDALRLPPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSR 166
S++ P +PGR P PPPP ERP P P + P P P P SR
Sbjct: 342 SSSTPPLPSPGRSG----PLPPPPSERPPPP----VRDPPGRSGPLPPPPPVSR 387
Score = 50.8 bits (120), Expect = 6e-07
Identities = 45/152 (29%), Positives = 56/152 (36%), Gaps = 32/152 (21%)
Query: 25 RRAPLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGP 84
R++PL + PP P P R ++ PPPP P R P P + P
Sbjct: 236 RQSPLSSSSPFSNRPPLPPTPSRALDD--KPPPPPPPVGNRPSIHREAVPPPPPQNNKPP 293
Query: 85 WTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPP-----ER 139
+ P R S+ AP P R PPP PP E
Sbjct: 294 VPSTP----------------------RPSASSQAPPPPPPPSRPGPPPLPPSSSGNDET 331
Query: 140 PRLPPAGLAGGPADSAPPSPAPAPRSRPAPRP 171
PRLP L+ + S PP P+P RS P P P
Sbjct: 332 PRLPQRNLS--LSSSTPPLPSPG-RSGPLPPP 360
Score = 46.6 bits (109), Expect = 1e-05
Identities = 37/124 (29%), Positives = 46/124 (37%), Gaps = 30/124 (24%)
Query: 17 PHSQVSLARRAPLMFGPGLRDP--PPPRPAPPRPGEEPGNRH---PPPPAARTHPGSCRA 71
P +SL+ P + PG P PPP PP P +P R PPPP + + RA
Sbjct: 335 PQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRA 394
Query: 72 RCPSPAAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPP 131
+P P R D + RP LP P R + PP
Sbjct: 395 LPATP----------QLPSRSGVDSPRSGPRPP--------LP-------PDRPSAGAPP 429
Query: 132 PPPP 135
PPPP
Sbjct: 430 PPPP 433
Score = 46.2 bits (108), Expect = 1e-05
Identities = 45/146 (30%), Positives = 54/146 (36%), Gaps = 32/146 (21%)
Query: 39 PPPRPAPPRPGEEP------GNRHPPP-PAARTHPGSCRARCPSPAAGGLRGPWTAAPGR 91
PPP P P RPG P GN P P S PSP G GP P
Sbjct: 307 PPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSP---GRSGPLPPPPSE 363
Query: 92 Q-----RADEGAAAARP-----ERQRVWARRLPGSAAAPA-PGRDALRLPPPPPPPPERP 140
+ R G + P R +R LP + P+ G D+ R P PP PP+R
Sbjct: 364 RPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDR- 422
Query: 141 RLPPAGLAGGPADSAPPSPAPAPRSR 166
P+ APP P P+ R
Sbjct: 423 ----------PSAGAPPPPPPSTSIR 438
Score = 29.3 bits (64), Expect = 1.8
Identities = 17/35 (48%), Positives = 18/35 (51%), Gaps = 5/35 (14%)
Query: 140 PRLPPAGLAGGPADSAPP-SPAPAPRSRPAPRPGH 173
P LPP GG + SA P SP P P P PGH
Sbjct: 127 PLLPP----GGRSTSAKPFSPPSGPGRFPVPSPGH 157
Score = 28.9 bits (63), Expect = 2.4
Identities = 18/52 (34%), Positives = 19/52 (36%), Gaps = 7/52 (13%)
Query: 120 PAPGRDALRLPPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRPAPRP 171
P GR P PP P R +P G GP P P P PRP
Sbjct: 130 PPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGP-------PEPQRNRMPPPRP 174
Score = 28.9 bits (63), Expect = 2.4
Identities = 12/28 (42%), Positives = 13/28 (46%)
Query: 37 DPPPPRPAPPRPGEEPGNRHPPPPAART 64
D P P PP P + P PPPP T
Sbjct: 408 DSPRSGPRPPLPPDRPSAGAPPPPPPST 435
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 57.0 bits (136), Expect = 8e-09
Identities = 57/186 (30%), Positives = 69/186 (37%), Gaps = 34/186 (18%)
Query: 16 RPHSQVSLARRAPLMFGPGLRDPPPP----RPAPPRP--GEEPGNRHPPPPAA-RTHPGS 68
+P S S R P+ PG R PP R PPRP G +P + PP P+ R S
Sbjct: 139 KPFSPPSGPGRFPVP-SPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSS 197
Query: 69 CRARCPSPAAGGLRGPWTAA-----PGRQRADEGAAAARPE---RQRVWARRLPGSAAAP 120
R P GG R P PG + G + R ++ R P P
Sbjct: 198 PHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPP---LPP 254
Query: 121 APGRDALRLPPPPPPP---------------PERPRLPPAGLAGGPADSAPPSPAPAPRS 165
P R PPPPPPP P + PP P+ S+ P P P S
Sbjct: 255 TPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPS 314
Query: 166 RPAPRP 171
RP P P
Sbjct: 315 RPGPPP 320
Score = 52.4 bits (124), Expect = 2e-07
Identities = 53/174 (30%), Positives = 66/174 (37%), Gaps = 21/174 (12%)
Query: 3 NKASGRRQGRARGRPHSQVS-LARRAPLMFGPGL----RDPPPPRPAPPRPGEEPGNRHP 57
N+ + G R P S S + R PL P + PPPP P RP P
Sbjct: 225 NRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPP 284
Query: 58 PPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADE--GAAAARPERQRVWARRLPG 115
PPP P P P+A P P R +++ E R+ R L
Sbjct: 285 PPPQNNKPPVPST---PRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSL 341
Query: 116 SAAAP---APGRDALRLPPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSR 166
S++ P +PGR P PPPP ERP P P + P P P P SR
Sbjct: 342 SSSTPPLPSPGRSG----PLPPPPSERPPPP----VRDPPGRSGPLPPPPPVSR 387
Score = 50.8 bits (120), Expect = 6e-07
Identities = 45/152 (29%), Positives = 56/152 (36%), Gaps = 32/152 (21%)
Query: 25 RRAPLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGP 84
R++PL + PP P P R ++ PPPP P R P P + P
Sbjct: 236 RQSPLSSSSPFSNRPPLPPTPSRALDD--KPPPPPPPVGNRPSIHREAVPPPPPQNNKPP 293
Query: 85 WTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPP-----ER 139
+ P R S+ AP P R PPP PP E
Sbjct: 294 VPSTP----------------------RPSASSQAPPPPPPPSRPGPPPLPPSSSGNDET 331
Query: 140 PRLPPAGLAGGPADSAPPSPAPAPRSRPAPRP 171
PRLP L+ + S PP P+P RS P P P
Sbjct: 332 PRLPQRNLS--LSSSTPPLPSPG-RSGPLPPP 360
Score = 46.6 bits (109), Expect = 1e-05
Identities = 37/124 (29%), Positives = 46/124 (37%), Gaps = 30/124 (24%)
Query: 17 PHSQVSLARRAPLMFGPGLRDP--PPPRPAPPRPGEEPGNRH---PPPPAARTHPGSCRA 71
P +SL+ P + PG P PPP PP P +P R PPPP + + RA
Sbjct: 335 PQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRA 394
Query: 72 RCPSPAAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPP 131
+P P R D + RP LP P R + PP
Sbjct: 395 LPATP----------QLPSRSGVDSPRSGPRPP--------LP-------PDRPSAGAPP 429
Query: 132 PPPP 135
PPPP
Sbjct: 430 PPPP 433
Score = 46.2 bits (108), Expect = 1e-05
Identities = 45/146 (30%), Positives = 54/146 (36%), Gaps = 32/146 (21%)
Query: 39 PPPRPAPPRPGEEP------GNRHPPP-PAARTHPGSCRARCPSPAAGGLRGPWTAAPGR 91
PPP P P RPG P GN P P S PSP G GP P
Sbjct: 307 PPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSP---GRSGPLPPPPSE 363
Query: 92 Q-----RADEGAAAARP-----ERQRVWARRLPGSAAAPA-PGRDALRLPPPPPPPPERP 140
+ R G + P R +R LP + P+ G D+ R P PP PP+R
Sbjct: 364 RPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDR- 422
Query: 141 RLPPAGLAGGPADSAPPSPAPAPRSR 166
P+ APP P P+ R
Sbjct: 423 ----------PSAGAPPPPPPSTSIR 438
Score = 29.3 bits (64), Expect = 1.8
Identities = 17/35 (48%), Positives = 18/35 (51%), Gaps = 5/35 (14%)
Query: 140 PRLPPAGLAGGPADSAPP-SPAPAPRSRPAPRPGH 173
P LPP GG + SA P SP P P P PGH
Sbjct: 127 PLLPP----GGRSTSAKPFSPPSGPGRFPVPSPGH 157
Score = 28.9 bits (63), Expect = 2.4
Identities = 18/52 (34%), Positives = 19/52 (36%), Gaps = 7/52 (13%)
Query: 120 PAPGRDALRLPPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRPAPRP 171
P GR P PP P R +P G GP P P P PRP
Sbjct: 130 PPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGP-------PEPQRNRMPPPRP 174
Score = 28.9 bits (63), Expect = 2.4
Identities = 12/28 (42%), Positives = 13/28 (46%)
Query: 37 DPPPPRPAPPRPGEEPGNRHPPPPAART 64
D P P PP P + P PPPP T
Sbjct: 408 DSPRSGPRPPLPPDRPSAGAPPPPPPST 435
>gi|22027541 programmed cell death 7 [Homo sapiens]
Length = 485
Score = 57.0 bits (136), Expect = 8e-09
Identities = 52/148 (35%), Positives = 57/148 (38%), Gaps = 27/148 (18%)
Query: 28 PLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTA 87
P FG G PPPP+P PP P P PPP + P R P P G P+
Sbjct: 4 PPFFGQGRPGPPPPQPPPPAPFGCP----PPPLPSPAFPPPLPQR-PGPFPGA-SAPFLQ 57
Query: 88 APGRQRADEGAAAARPERQRVWARRLPGSAAA--PAPGRDALRLPPPPPPPPERPRLPPA 145
P A R A R G A A P P PPP PPPP + R P
Sbjct: 58 PP----------LALQPRASAEASRGGGGAGAFYPVP-------PPPLPPPPPQCRPFPG 100
Query: 146 GLAGGPADSAPPSPAP--APRSRPAPRP 171
AG PP P P +PR AP P
Sbjct: 101 TDAGERPRPPPPGPGPPWSPRWPEAPPP 128
Score = 28.5 bits (62), Expect = 3.1
Identities = 13/24 (54%), Positives = 13/24 (54%), Gaps = 2/24 (8%)
Query: 38 PPPPRPAPPRPGEEPGNRHPPPPA 61
PPPP P PP P PPPPA
Sbjct: 109 PPPPGPGPPWSPRWP--EAPPPPA 130
Score = 28.1 bits (61), Expect = 4.1
Identities = 19/52 (36%), Positives = 21/52 (40%), Gaps = 8/52 (15%)
Query: 127 LRLPP------PPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRPAPRPG 172
+ LPP P PPPP PPA P P+ P RP P PG
Sbjct: 1 MALPPFFGQGRPGPPPP--QPPPPAPFGCPPPPLPSPAFPPPLPQRPGPFPG 50
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 57.0 bits (136), Expect = 8e-09
Identities = 49/142 (34%), Positives = 54/142 (38%), Gaps = 29/142 (20%)
Query: 39 PPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQ--RADE 96
PPP PAPP P P P A P AR P AA P + P + RA
Sbjct: 127 PPPTPAPPPP---------PAPVAAAAP----ARAPRAAAAAATAPPSPGPAQPGPRAQR 173
Query: 97 GAAAARPERQRVWARRLPGSAAAPAPGRDALRLPP-------PPPPPPERPRLPPAGLAG 149
A A P A P + A PA R R PP PP PPP +P PP
Sbjct: 174 AAPLAAPPP----APAAPPAVAPPAGPR---RAPPPAVAAREPPLPPPPQPPAPPQQQQP 226
Query: 150 GPADSAPPSPAPAPRSRPAPRP 171
P PP A R+ A RP
Sbjct: 227 PPPQPQPPPEGGAVRAGGAARP 248
Score = 53.5 bits (127), Expect = 9e-08
Identities = 43/142 (30%), Positives = 47/142 (33%), Gaps = 14/142 (9%)
Query: 34 GLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQR 93
G P PPR P PP PA P A P+ A TA P
Sbjct: 105 GATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPS--- 161
Query: 94 ADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPERPRLPPAGLAGGPAD 153
G A P QR P +A PAP PP PP R PP +A
Sbjct: 162 --PGPAQPGPRAQRA----APLAAPPPAPAA-----PPAVAPPAGPRRAPPPAVAAREPP 210
Query: 154 SAPPSPAPAPRSRPAPRPGHAQ 175
PP PAP + P P Q
Sbjct: 211 LPPPPQPPAPPQQQQPPPPQPQ 232
Score = 53.1 bits (126), Expect = 1e-07
Identities = 46/135 (34%), Positives = 49/135 (36%), Gaps = 19/135 (14%)
Query: 42 RPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADEGAAA- 100
R PPR G P PP A R P + A P P T AP A AAA
Sbjct: 98 RVQPPRRGATPP---APPRAPRGAPAAAAAAAPPP---------TPAPPPPPAPVAAAAP 145
Query: 101 ARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPERPRLPPAGLAGGPADSAPPS-- 158
AR R A P S PG A R P PPP P GP + PP+
Sbjct: 146 ARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVA 205
Query: 159 ----PAPAPRSRPAP 169
P P P PAP
Sbjct: 206 AREPPLPPPPQPPAP 220
Score = 43.5 bits (101), Expect = 9e-05
Identities = 42/134 (31%), Positives = 51/134 (38%), Gaps = 29/134 (21%)
Query: 25 RRAPLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPA------- 77
RRAP P + PP P PP+P P + PPPP + P R A
Sbjct: 197 RRAP---PPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLRE 253
Query: 78 -------AGGLRGPWTAAPGRQRA---DEGAAAARPERQRVWARRLPGSAAAPAPGRDAL 127
+GG G T GR + +E AA R ER R+ A LP PG
Sbjct: 254 VVRYLGGSGGAGGRLTR--GRVQGLLEEEAAARGRLERTRLGALALP---RGDRPG---- 304
Query: 128 RLPPPPPPPPERPR 141
R PP P R +
Sbjct: 305 RAPPAASARPSRSK 318
Score = 42.4 bits (98), Expect = 2e-04
Identities = 40/125 (32%), Positives = 45/125 (36%), Gaps = 27/125 (21%)
Query: 26 RAPLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPW 85
RAP PP P PA P P + PP P+PAA P
Sbjct: 147 RAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPP-------------PAPAA-----PP 188
Query: 86 TAAP--GRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPERPRLP 143
AP G +RA A AAR LP PAP + PP P PPPE +
Sbjct: 189 AVAPPAGPRRAPPPAVAAREP-------PLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVR 241
Query: 144 PAGLA 148
G A
Sbjct: 242 AGGAA 246
Score = 33.9 bits (76), Expect = 0.074
Identities = 33/113 (29%), Positives = 42/113 (37%), Gaps = 15/113 (13%)
Query: 60 PAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADEGAAAARPERQR----VWARRLPG 115
PA H R P A ++ WT Q DEG A R + A G
Sbjct: 356 PAGAQHHQLNGERGPQSAKERVK-EWTPCGPHQGQDEGRGPAPGSGTRQVFSMAAMNKEG 414
Query: 116 SAAAPAPGRDALRLPPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRPA 168
A+ A G D+ P P P PP +P LP AD P P + +P+
Sbjct: 415 GTASVATGPDS---PSPVPLPPGKPALP-------GADGTPFGCPPGRKEKPS 457
>gi|21704281 junctophilin 2 isoform 1 [Homo sapiens]
Length = 696
Score = 56.6 bits (135), Expect = 1e-08
Identities = 50/158 (31%), Positives = 61/158 (38%), Gaps = 35/158 (22%)
Query: 38 PPPPRPAP-------PRP-GEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAP 89
P PPR +P PRP G P PP R PG + SP G W P
Sbjct: 463 PQPPRESPQLHERETPRPEGGSPSPAGTPPQPKRPRPGVSKDGLLSP------GAWNGEP 516
Query: 90 GRQRA-----DEGAAAARPERQRVWARRLPGSAAAPAPGRD------------ALRLPPP 132
+ + EGA P R + A PAP R+ A+R PP
Sbjct: 517 SGEGSRSVTPSEGAGRRSPARPATERMAIEALQAPPAPSREPEVALYQGYHSYAVRTTPP 576
Query: 133 PPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRPAPR 170
PPP E P ++G ++SAP SPA AP P R
Sbjct: 577 EPPPFEDQ--PEPEVSG--SESAPSSPATAPLQAPTLR 610
Score = 28.9 bits (63), Expect = 2.4
Identities = 25/82 (30%), Positives = 29/82 (35%), Gaps = 2/82 (2%)
Query: 92 QRADEGAAAARPERQ--RVWARRLPGSAAAPAPGRDALRLPPPPPPPPERPRLPPAGLAG 149
+ A++ A AA E R AR L P P RL E PP AG
Sbjct: 399 EAAEQAALAANQESNIARTLARELAPDFYQPGPEYQKRRLLQEILENSESLLEPPDRGAG 458
Query: 150 GPADSAPPSPAPAPRSRPAPRP 171
PP +P R PRP
Sbjct: 459 AAGLPQPPRESPQLHERETPRP 480
Score = 28.9 bits (63), Expect = 2.4
Identities = 19/53 (35%), Positives = 20/53 (37%), Gaps = 5/53 (9%)
Query: 120 PAPGRDALRLPPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRPAPRPG 172
P G A LP PP P+ GG PSPA P PRPG
Sbjct: 453 PDRGAGAAGLPQPPRESPQLHERETPRPEGG-----SPSPAGTPPQPKRPRPG 500
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 56.2 bits (134), Expect = 1e-08
Identities = 48/143 (33%), Positives = 52/143 (36%), Gaps = 21/143 (14%)
Query: 29 LMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAA 88
++ GPG D P G P P P A PA G P
Sbjct: 491 ILRGPG--DAVSIEILPVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPL 548
Query: 89 PGRQRADEGAAAARPERQRVWARRLPGS----AAAPAPGRDALRLPPPPPPPPERPRLPP 144
PG E +A P+ A LPGS A P PG LPPPPPPPP PP
Sbjct: 549 PGLPSPQEAPPSAPPQ-----APPLPGSPEPPPAPPLPG----DLPPPPPPPP-----PP 594
Query: 145 AGLAGGPADSAPPSPAPAPRSRP 167
G GP PP P P P P
Sbjct: 595 PG-TDGPVPPPPPPPPPPPGGPP 616
Score = 49.7 bits (117), Expect = 1e-06
Identities = 39/126 (30%), Positives = 43/126 (34%), Gaps = 34/126 (26%)
Query: 38 PPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADEG 97
PPPP P P P E P + PP A PGS P G L P P
Sbjct: 544 PPPPLPGLPSPQEAPPSA---PPQAPPLPGSPEPPPAPPLPGDLPPPPPPPP-------- 592
Query: 98 AAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPERPRLPPAGLAGGPADSAPP 157
P PG D +PPPPPPPP P PP L ++ P
Sbjct: 593 ----------------------PPPGTDG-PVPPPPPPPPPPPGGPPDALGRRDSELGPG 629
Query: 158 SPAPAP 163
A P
Sbjct: 630 VKAKKP 635
Score = 41.6 bits (96), Expect = 4e-04
Identities = 43/149 (28%), Positives = 47/149 (31%), Gaps = 31/149 (20%)
Query: 54 NRHPP-----PPAARTHPGSCRARCPSPAAGGL----RGPWTAAP------------GRQ 92
+R PP PPAA T P + + GL RGP A G
Sbjct: 456 SRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGD 515
Query: 93 RADEGAAAARPERQRVWARR-LPGSAAAPAPGRDAL--------RLPPPPPPPPERPRLP 143
G P A PG+A P P L PP PP P P P
Sbjct: 516 APTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPP 575
Query: 144 PAGLAGGPADSAPPSPAPAP-RSRPAPRP 171
PA G PP P P P P P P
Sbjct: 576 PAPPLPGDLPPPPPPPPPPPGTDGPVPPP 604
Score = 30.0 bits (66), Expect = 1.1
Identities = 15/34 (44%), Positives = 16/34 (47%)
Query: 27 APLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPP 60
AP + G PPPP P P G P PPPP
Sbjct: 577 APPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPP 610
>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
Length = 1295
Score = 55.8 bits (133), Expect = 2e-08
Identities = 52/168 (30%), Positives = 61/168 (36%), Gaps = 39/168 (23%)
Query: 38 PPPPRPAPPRPGEEPGNRHPPPPAART------------HPGSCR-----ARCPSPAAG- 79
PPPPRP P P R PPP AR+ PG+ R PSP AG
Sbjct: 1108 PPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGAPKSPGTTRKDNIGRSQPSPQAGL 1167
Query: 80 ---GLRGPWTAAP-----------GRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRD 125
G G TA P + A A PE Q + GS P P +
Sbjct: 1168 AGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKP 1227
Query: 126 ALRLPPPP--PPPPERPRLPPAGLA-----GGPADSAPPSPAPAPRSR 166
PP PPP +R + P +A GP + P P PRSR
Sbjct: 1228 QAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSR 1275
Score = 41.2 bits (95), Expect = 5e-04
Identities = 41/134 (30%), Positives = 49/134 (36%), Gaps = 15/134 (11%)
Query: 43 PAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADEGAAAAR 102
P +P G P + RT P C SP GP + P R
Sbjct: 1027 PQHLQPSSSSGLGTSPSSSPRTSP------CQSPTIS--EGPVPSLPIRPSRAPSRTPGP 1078
Query: 103 PERQRVWARRLPGSAAAPAPGRD-ALRLPP--PPPPPPERPRLPPAGLAGGPADSAPPSP 159
P Q + + A P P +D A L P PPPP P P PA P S SP
Sbjct: 1079 PSAQ---SSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSP 1135
Query: 160 APAPRSRPAPR-PG 172
AP + AP+ PG
Sbjct: 1136 APTRKEFGAPKSPG 1149
Score = 39.3 bits (90), Expect = 0.002
Identities = 50/173 (28%), Positives = 65/173 (37%), Gaps = 30/173 (17%)
Query: 19 SQVSLARRAPLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAA 78
S S R +P P + + P P P RP P +R P PP+A++ P + P P
Sbjct: 1041 SPSSSPRTSPCQ-SPTISEGPVPS-LPIRPSRAP-SRTPGPPSAQSSPIDAQPATPLPQK 1097
Query: 79 GGLR-------------GPWT--AAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPG 123
+ P T A P R GA + P R+ A + PG+ G
Sbjct: 1098 DPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGAPKSPGTTRKDNIG 1157
Query: 124 RD------ALRLPPPPPPPPERPRLPP-AGLAGGPADSAPPSPAPAPRSRPAP 169
R L P P RP +PP AG+ SAP S A A R P
Sbjct: 1158 RSQPSPQAGLAGPGPAGYSTARPTIPPRAGVI-----SAPQSHARASAGRLTP 1205
Score = 35.8 bits (81), Expect = 0.019
Identities = 41/152 (26%), Positives = 55/152 (36%), Gaps = 13/152 (8%)
Query: 8 RRQGRARGRPHSQVSLARRAPLMFGPGLRDPPPPRPA-PPRPGE-EPGNRHPPPPAARTH 65
R+ R +P Q LA GPG RP PPR G H A R
Sbjct: 1152 RKDNIGRSQPSPQAGLA-------GPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLT 1204
Query: 66 PGSCRARCPSPAAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPG-R 124
P S +++ + G P P Q A ++ P QR+ +P +A P G +
Sbjct: 1205 PES-QSKTSETSKGSTFLPEPLKP--QAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQ 1261
Query: 125 DALRLPPPPPPPPERPRLPPAGLAGGPADSAP 156
L PP PPP P+ + P P
Sbjct: 1262 PNLETPPQPPPRSRSSHSLPSEASSQPQQEQP 1293
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 55.8 bits (133), Expect = 2e-08
Identities = 48/154 (31%), Positives = 60/154 (38%), Gaps = 31/154 (20%)
Query: 37 DPPPP-------------RPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRG 83
+PPPP RPA + G P PPPP A P P P G
Sbjct: 1162 EPPPPLSVYHNGTGTVRRRPASEQAG--PPELPPPPPPAEPPPTDLAHLPPLPPPEGE-- 1217
Query: 84 PWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPG------RDALRLPPP----P 133
P + +P ++ P S P PG + A PPP P
Sbjct: 1218 --ARKPAKPPVSPKPVLTQPV-PKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKP 1274
Query: 134 PPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRP 167
PPPP P+ P +AG P+ SA PSPAP+P +P
Sbjct: 1275 PPPPTAPK-PVKAVAGLPSGSAGPSPAPSPARQP 1307
Score = 45.4 bits (106), Expect = 2e-05
Identities = 47/151 (31%), Positives = 59/151 (39%), Gaps = 23/151 (15%)
Query: 19 SQVSLARRAPLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAA 78
S +++ PL GPG + PP P + PPPP P A PS +A
Sbjct: 1242 SPTPTSKKVPLP-GPGSPEVKRAHGTPP-----PVSPKPPPPPTAPKPVKAVAGLPSGSA 1295
Query: 79 GGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPE 138
G P +P RQ AA A+P P A P+PG AL +P P
Sbjct: 1296 GPSPAP---SPARQPP---AALAKPPGTPPSLGASP--AKPPSPGAPALHVPAKP----- 1342
Query: 139 RPRLPPAGLAGGPADSAPP---SPAPAPRSR 166
PR A A A APP SP + R +
Sbjct: 1343 -PRAAAAAAAAAAAPPAPPEGASPGDSARQK 1372
Score = 42.4 bits (98), Expect = 2e-04
Identities = 37/129 (28%), Positives = 44/129 (34%), Gaps = 18/129 (13%)
Query: 40 PPRPAPPRPGEEPGNRH--PPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADEG 97
PP P PR PG H PP +T PGS +A L GP AP +
Sbjct: 757 PPVPGKPRQVLPPGTSHFTPPQTPTKTRPGSPQA---------LGGPHGPAPATAKVKPT 807
Query: 98 AAAARPERQRVWARRLPGSAA-------APAPGRDALRLPPPPPPPPERPRLPPAGLAGG 150
P + + R LP S P P + P P PP P P
Sbjct: 808 PQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAPPPVPTAVPTLCLPP 867
Query: 151 PADSAPPSP 159
AD+ P P
Sbjct: 868 EADAEPGRP 876
Score = 41.2 bits (95), Expect = 5e-04
Identities = 33/133 (24%), Positives = 42/133 (31%), Gaps = 34/133 (25%)
Query: 46 PRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADEGAAAARPER 105
P+ E PPPP + H G+ G RP
Sbjct: 1152 PKAKEREAGPEPPPPLSVYHNGT----------------------------GTVRRRPAS 1183
Query: 106 QRVWARRLPGSAA-APAPGRDALRLPPPPPPP-----PERPRLPPAGLAGGPADSAPPSP 159
++ LP A P D LPP PPP P +P + P + P SP
Sbjct: 1184 EQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQGSP 1243
Query: 160 APAPRSRPAPRPG 172
P + P P PG
Sbjct: 1244 TPTSKKVPLPGPG 1256
Score = 40.4 bits (93), Expect = 8e-04
Identities = 42/142 (29%), Positives = 54/142 (38%), Gaps = 20/142 (14%)
Query: 50 EEPGNRHPPPPAARTHPGSC---RARCPSPA----AGGLRGPWTAAPGRQR--ADEGAAA 100
E+P + PP P A T S RAR S + G GP + Q DEG A
Sbjct: 676 EKPSSHLPPTPRATTRQDSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGPAP 735
Query: 101 ARPERQRVWARR---LPGSAAAPAPGRDALRLPP-----PPPPPPERPRLPPAGLAGGPA 152
P R+ R + ++ P PG+ LPP PP P + R GGP
Sbjct: 736 GTPPREARPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPGSPQALGGPH 795
Query: 153 DSAPPSPAPAPRSR---PAPRP 171
AP + P + P RP
Sbjct: 796 GPAPATAKVKPTPQLLPPTERP 817
Score = 36.6 bits (83), Expect = 0.011
Identities = 41/151 (27%), Positives = 47/151 (31%), Gaps = 38/151 (25%)
Query: 52 PGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTA-----------APGRQRADEGAAA 100
PG P P G R R PS G+ GP A +Q E
Sbjct: 1081 PGESADPGPFVEDGTGRQRPRGPSKGEAGVEGPPLAKVEASATLKRRIRAKQNQQENVKF 1140
Query: 101 ARPERQRVWAR-RLPGSAAAPAP---------GRDALRLPP----------PPPPPPERP 140
E V R + A P P G +R P PPPPPP P
Sbjct: 1141 ILTESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEP 1200
Query: 141 RLPPAGLAGGPADSAPPSPAPAPRSRPAPRP 171
PP LA PP P P +R +P
Sbjct: 1201 --PPTDLA-----HLPPLPPPEGEARKPAKP 1224
Score = 34.3 bits (77), Expect = 0.057
Identities = 36/133 (27%), Positives = 42/133 (31%), Gaps = 24/133 (18%)
Query: 43 PAPPRPGEEPGNRHPP----PPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADEGA 98
PA P P P P PP A PG + R S + A+ DE
Sbjct: 846 PAAPGPAPPPVPTAVPTLCLPPEADAEPGRPKKRAHS------LNRYAASDSEPERDELL 899
Query: 99 AAARPERQRVWARRLPGSAAAPAPG--------------RDALRLPPPPPPPPERPRLPP 144
A RR+ S + AP R + PPPPPP L
Sbjct: 900 VPAAAGPYATVQRRVGRSHSVRAPAGADKNVNRSQSFAVRPRKKGPPPPPPKRSSSALAS 959
Query: 145 AGLAGGPADSAPP 157
A LA P A P
Sbjct: 960 ANLADEPVPDAEP 972
Score = 33.1 bits (74), Expect = 0.13
Identities = 41/170 (24%), Positives = 53/170 (31%), Gaps = 38/170 (22%)
Query: 15 GRPHSQVSLARRAPLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCP 74
G P ++R + G PPR A P R PP PG R P
Sbjct: 713 GPPGPSSPMSRSQEYLLDEGPAPGTPPREARPGRHGHSIKRASVPPV----PGKPRQVLP 768
Query: 75 SPAAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPP 134
P P T P + R + + G PAP ++ P
Sbjct: 769 -PGTSHFTPPQT----------------PTKTRPGSPQALGGPHGPAPATAKVKPTPQLL 811
Query: 135 PPPERPRLP----------------PAGLAGGPADSAP-PSPAPAPRSRP 167
PP ERP P P + G +AP P+P P P + P
Sbjct: 812 PPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAPPPVPTAVP 861
Score = 26.9 bits (58), Expect = 9.0
Identities = 16/58 (27%), Positives = 21/58 (36%), Gaps = 13/58 (22%)
Query: 126 ALRLPPPPPPPPERPRLPP-------------AGLAGGPADSAPPSPAPAPRSRPAPR 170
A+ PPPP P P + P GPA+ P + P+ P PR
Sbjct: 630 AIESPPPPEPTPADCQSPKMTTFQDSELSDELQAAMTGPAEVGPTTEKPSSHLPPTPR 687
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 55.8 bits (133), Expect = 2e-08
Identities = 47/166 (28%), Positives = 61/166 (36%), Gaps = 40/166 (24%)
Query: 38 PPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPA-------AGGLRGPW----- 85
PPPP P P P + PPPP+ P + + P P A PW
Sbjct: 471 PPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTT 530
Query: 86 --TAAPG--------RQRADEGAAAARPERQR----------VWARRLPGSAAAPAP--- 122
T + G +Q+A A+ P+ Q V PG+ P P
Sbjct: 531 TTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPP 590
Query: 123 -GRDALRLPPPPPPPPERP----RLPPAGLAGGPADSAPPSPAPAP 163
+ PPPPPPPP P + G+AG P PP+P P P
Sbjct: 591 GSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPP 636
Score = 38.1 bits (87), Expect = 0.004
Identities = 37/141 (26%), Positives = 44/141 (31%), Gaps = 34/141 (24%)
Query: 28 PLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTA 87
P+ P PPPP PP P P N+ P PP P + +P G+
Sbjct: 412 PMQHNPN--GPPPPWMQPPPP---PMNQGPHPPGHHGPPPMDQYLGSTPVGSGV------ 460
Query: 88 APGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPERPRLPPAGL 147
R +G P P P PPPPPP + P P L
Sbjct: 461 ----YRLHQGKGMMPP----------PPMGMMP---------PPPPPPSGQPPPPPSGPL 497
Query: 148 AGGPADSAPPSPAPAPRSRPA 168
P P P P S A
Sbjct: 498 PPWQQQQQQPPPPPPPSSSMA 518
Score = 31.2 bits (69), Expect = 0.48
Identities = 18/66 (27%), Positives = 26/66 (39%), Gaps = 5/66 (7%)
Query: 8 RRQGRARGRPHSQVSLARRAPLMFGPGLRDPPPPRPAPPRPGEEPGN-----RHPPPPAA 62
++Q A P + + PG++ P PP PP P PG+ PPPP
Sbjct: 546 QQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPP 605
Query: 63 RTHPGS 68
P +
Sbjct: 606 PMDPSN 611
Score = 29.3 bits (64), Expect = 1.8
Identities = 20/64 (31%), Positives = 25/64 (39%), Gaps = 11/64 (17%)
Query: 117 AAAPAPGRDALRLPPPPPPPPERPRLPPAGLAGGPADS---------APPSPAPAPRSRP 167
A+AP P A PPPP + P + GP++S P P P S P
Sbjct: 341 ASAPRPAAPANN--PPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHSFP 398
Query: 168 APRP 171
P P
Sbjct: 399 HPLP 402
Score = 28.9 bits (63), Expect = 2.4
Identities = 44/186 (23%), Positives = 52/186 (27%), Gaps = 56/186 (30%)
Query: 27 APLMFGPGLRDPPPPRP--APPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGP 84
AP+ G P P + PRP N PPPP+ + S R P
Sbjct: 323 APVPASVGSTSGPATTPLASAPRPAAPANN--PPPPSLMSTTQS-------------RPP 367
Query: 85 W-TAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRL-------PPP---P 133
W + P R G P P + G + PPP P
Sbjct: 368 WMNSGPSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQP 427
Query: 134 PPPPERPRLPPAGLAGGPA-----DSAP-----------------------PSPAPAPRS 165
PPPP P G G P S P P P P P
Sbjct: 428 PPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSG 487
Query: 166 RPAPRP 171
+P P P
Sbjct: 488 QPPPPP 493
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 55.8 bits (133), Expect = 2e-08
Identities = 54/172 (31%), Positives = 65/172 (37%), Gaps = 31/172 (18%)
Query: 17 PHSQVSLARRAPLMFGPGLRDPPPPRPA--PPR--------PGEEPGNRHPPPPAARTHP 66
P S SL +APL P L P P RP PP P E P + PPP A T P
Sbjct: 773 PSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLP 832
Query: 67 G----SCRARCPSPAAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAA--- 119
G + P PA+ P APG + + PE A LP S+ +
Sbjct: 833 GIFVIQNQLGVPPPASN----PAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAV 888
Query: 120 ----------PAPGRDALRLPPPPPPPPERPRLPPAGLAGGPADSAPPSPAP 161
PAP +L PP P + PP L P +APP P P
Sbjct: 889 ASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPP 940
Score = 40.8 bits (94), Expect = 6e-04
Identities = 46/164 (28%), Positives = 64/164 (39%), Gaps = 19/164 (11%)
Query: 19 SQVSLARRAPLMFGPG---LRDPPPPR-PAPPRPGEEPGNRHPPPPAARTHPGSCRARCP 74
SQ L+ P + P + PPP + PAP P + P P ++ P A P
Sbjct: 705 SQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASP----APAP 760
Query: 75 S-PAAGGLRGPWTAA----PGRQRADEGAAAARPERQRVWAR--RLPGSAAAPAPGRDAL 127
PAA L+GP ++ P + + P R +R P S + P P L
Sbjct: 761 QIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRP-PSEPPL 819
Query: 128 RLPPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRPAPRP 171
P PPP P LP + PP+ PAP + P+P
Sbjct: 820 H---PCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQP 860
Score = 40.4 bits (93), Expect = 8e-04
Identities = 43/149 (28%), Positives = 48/149 (32%), Gaps = 31/149 (20%)
Query: 38 PPPPRPAPPRPGEEPGN-RHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADE 96
PP P P PP G+ G HPPP A P CP LR + G A E
Sbjct: 1346 PPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLP---LRKTYRENVGGPGAPE 1402
Query: 97 GAAAARPERQRVWARRLPGSAAAPAPGR----------------DALRLPPPPPPPPERP 140
G A R G + AP P + D L PPPE P
Sbjct: 1403 GTPAGRAR----------GGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPE-P 1451
Query: 141 RLPPAGLAGGPADSAPPSPAPAPRSRPAP 169
A G P AP P R +P
Sbjct: 1452 AASAAQGTGDPDWEAPGLPPAKRRKSESP 1480
Score = 36.2 bits (82), Expect = 0.015
Identities = 20/54 (37%), Positives = 23/54 (42%), Gaps = 7/54 (12%)
Query: 120 PAPGRDALRLPPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRPAPRPGH 173
P P + PPP PPPP PP G G D PP+ AP +P H
Sbjct: 1335 PPPATLKVAEPPPRPPPPP----PPTGQMNGTVDHPPPA---APERKPLGTAPH 1381
Score = 31.2 bits (69), Expect = 0.48
Identities = 21/63 (33%), Positives = 24/63 (38%), Gaps = 5/63 (7%)
Query: 117 AAAPAPGRDALRLPPPPPPPPERPRLPPAGLAGGPADSAPPSP-----APAPRSRPAPRP 171
AAA L + P P PP P GL A P +P AP + P P P
Sbjct: 609 AAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSP 668
Query: 172 GHA 174
G A
Sbjct: 669 GLA 671
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 55.5 bits (132), Expect = 2e-08
Identities = 52/155 (33%), Positives = 60/155 (38%), Gaps = 28/155 (18%)
Query: 28 PLMFGPGLRDPPP-PRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWT 86
P + G G+ PPP P P P PG PPPP PG+ P P G P
Sbjct: 1023 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL---PGA-GIPPPPPLPGAGIPPPP 1078
Query: 87 AAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPP----PERPRL 142
PG G P LPG+ P P + +PPPPP P P P L
Sbjct: 1079 PLPGA-----GIPPPPP---------LPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL 1124
Query: 143 PPAGLAGGP--ADSAPPSPAPAPR---SRPAPRPG 172
P AG+ P + P P P PR P P PG
Sbjct: 1125 PGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPG 1159
Score = 55.1 bits (131), Expect = 3e-08
Identities = 52/156 (33%), Positives = 58/156 (37%), Gaps = 22/156 (14%)
Query: 28 PLMFGPGLRDPPP-PRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWT 86
P + G G+ PPP P P P PG PPPP PG+ P P G P
Sbjct: 1078 PPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPL---PGA-GIPPPPPLPGAGIPPPP 1133
Query: 87 AAPGRQRADEGAAAARPERQRVWARR---LPGSAAAPAPGRDALRLPPPPPPP----PER 139
PG P RV LPG+ P P +PPPPP P P
Sbjct: 1134 PLPG------AGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPP 1187
Query: 140 PRLPPAGLAGGP----ADSAPPSPAPAPRSRPAPRP 171
P LP G+ P A PP P P PAP P
Sbjct: 1188 PPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAP 1223
Score = 54.3 bits (129), Expect = 5e-08
Identities = 55/163 (33%), Positives = 59/163 (36%), Gaps = 41/163 (25%)
Query: 33 PGLRDPPPPR-------PAPPRPGEE-------PGNRHPPPPAARTHPGSCRARCPSPAA 78
PG PPPP P PP PG PG PPPP PG+ P P
Sbjct: 916 PGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPL---PGA-GIPLPPPLP 971
Query: 79 GGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPP-- 136
G P PG G P LPG+ P P +PPPPP P
Sbjct: 972 GAGIPPPPPLPGA-----GIPPPPP---------LPGAGIPPPPPLPGAGIPPPPPLPGA 1017
Query: 137 --PERPRLPPAGLAGGP----ADSAPPSPAP-APRSRPAPRPG 172
P P LP AG+ P A PP P P A P P PG
Sbjct: 1018 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1060
Score = 54.3 bits (129), Expect = 5e-08
Identities = 54/153 (35%), Positives = 58/153 (37%), Gaps = 32/153 (20%)
Query: 33 PGLRDPPPPRPAP----PRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAA 88
PG PPPP P P P P PG PPPP PG+ P P G P
Sbjct: 949 PGAAIPPPP-PLPGAGIPLPPPLPGAGIPPPPPL---PGA-GIPPPPPLPGAGIPPPPPL 1003
Query: 89 PGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPP----PERPRLPP 144
PG G P LPG+ P P +PPPPP P P P LP
Sbjct: 1004 PGA-----GIPPPPP---------LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1049
Query: 145 AGLAGGP----ADSAPPSPAP-APRSRPAPRPG 172
AG+ P A PP P P A P P PG
Sbjct: 1050 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1082
Score = 53.9 bits (128), Expect = 7e-08
Identities = 52/156 (33%), Positives = 58/156 (37%), Gaps = 30/156 (19%)
Query: 28 PLMFGPGLRDPPP-PRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWT 86
P + G G+ PPP P P P PG PPPP PG+ P P G P
Sbjct: 1045 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL---PGA-GIPPPPPLPGAGIPPPP 1100
Query: 87 AAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPP-------PPPPER 139
PG G P LPG+ P P +PPPP PPPP
Sbjct: 1101 PLPG-----VGIPPPPP---------LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1146
Query: 140 PRL---PPAGLAGGPADSAPPSPAPAPRSRPAPRPG 172
PR+ PP L G PP P A P P PG
Sbjct: 1147 PRVGIPPPPPLPGAGIPPPPPLPG-AGIPPPPPLPG 1181
Score = 52.0 bits (123), Expect = 3e-07
Identities = 55/167 (32%), Positives = 60/167 (35%), Gaps = 40/167 (23%)
Query: 28 PLMFGPGLRDPPPPRPA------PPRPGEE-------PGNRHPPPPAARTHPGSCRARCP 74
PL L PPPP P PP PG PG PPPP PG+ P
Sbjct: 901 PLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPL---PGAAIPPPP 957
Query: 75 SPAAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPP 134
G+ P PG G P LPG+ P P +PPPPP
Sbjct: 958 PLPGAGIPLP-PPLPGA-----GIPPPPP---------LPGAGIPPPPPLPGAGIPPPPP 1002
Query: 135 PP----PERPRLPPAGLAGGP----ADSAPPSPAP-APRSRPAPRPG 172
P P P LP AG+ P A PP P P A P P PG
Sbjct: 1003 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1049
Score = 52.0 bits (123), Expect = 3e-07
Identities = 50/151 (33%), Positives = 56/151 (37%), Gaps = 27/151 (17%)
Query: 28 PLMFGPGLRDPPP-PRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWT 86
P + G G+ PPP P P P PG PPPP PG+ P P G P
Sbjct: 1056 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL---PGA-GIPPPPPLPGVGIPPPP 1111
Query: 87 AAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPP----PERPRL 142
PG G P LPG+ P P +PPPPP P P P L
Sbjct: 1112 PLPGA-----GIPPPPP---------LPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPL 1157
Query: 143 PPAGLAGGP----ADSAPPSPAPAPRSRPAP 169
P AG+ P A PP P P P P
Sbjct: 1158 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP 1188
Score = 51.2 bits (121), Expect = 4e-07
Identities = 49/155 (31%), Positives = 55/155 (35%), Gaps = 15/155 (9%)
Query: 33 PGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQ 92
PG+ P P A P+P G PPP P P AG L P G
Sbjct: 884 PGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIP 943
Query: 93 RADEGAAAARPERQRVWARR------LPGSAAAPAPGRDALRLPPPPPPP----PERPRL 142
AA P + LPG+ P P +PPPPP P P P L
Sbjct: 944 PPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1003
Query: 143 PPAGLAGGP----ADSAPPSPAP-APRSRPAPRPG 172
P AG+ P A PP P P A P P PG
Sbjct: 1004 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1038
Score = 51.2 bits (121), Expect = 4e-07
Identities = 49/151 (32%), Positives = 55/151 (36%), Gaps = 27/151 (17%)
Query: 28 PLMFGPGLRDPPP-PRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWT 86
P + G G+ PPP P P P PG PPPP PG P P G P
Sbjct: 1067 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL---PG-VGIPPPPPLPGAGIPPPP 1122
Query: 87 AAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPP----PERPRL 142
PG G P LPG+ P P + +PPPPP P P P L
Sbjct: 1123 PLPGA-----GIPPPPP---------LPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPL 1168
Query: 143 PPAGLAGGP----ADSAPPSPAPAPRSRPAP 169
P AG+ P PP P P P P
Sbjct: 1169 PGAGIPPPPPLPGVGIPPPPPLPGVGIPPPP 1199
Score = 48.9 bits (115), Expect = 2e-06
Identities = 46/141 (32%), Positives = 49/141 (34%), Gaps = 36/141 (25%)
Query: 28 PLMFGPGLRDPPP-PRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWT 86
P + G G+ PPP PR P P PG PPPP P P AG P
Sbjct: 1133 PPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPP-------------PLPGAG--IPPPP 1177
Query: 87 AAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPP------PPPERP 140
PG G P LPG P P +PPPPP PP P
Sbjct: 1178 PLPG-----VGIPPPPP---------LPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAP 1223
Query: 141 RLPPAGLAGGPADSAPPSPAP 161
LPP G P P S P
Sbjct: 1224 PLPPPGTGIPPPPLLPVSGPP 1244
Score = 48.1 bits (113), Expect = 4e-06
Identities = 50/151 (33%), Positives = 57/151 (37%), Gaps = 24/151 (15%)
Query: 33 PGLRDPPPPRPAP----PRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAA 88
PG PPPP P P P P PG PPPP PG+ P G+ P
Sbjct: 1092 PGAGIPPPP-PLPGVGIPPPPPLPGAGIPPPPPL---PGAGIPPPPPLPGAGIPPP---- 1143
Query: 89 PGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPP--PP--PERPRLPP 144
P R P LPG+ P P + +PPPPP P P LP
Sbjct: 1144 PPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPG 1203
Query: 145 AGLAGG---PADSAPPSPAPAPRSRPAPRPG 172
AG+ P PP+PAP P P PG
Sbjct: 1204 AGIPPPPPLPGMGIPPAPAP-----PLPPPG 1229
Score = 46.6 bits (109), Expect = 1e-05
Identities = 48/146 (32%), Positives = 52/146 (35%), Gaps = 21/146 (14%)
Query: 39 PPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPS---PAAGGLRGPWTAAPGRQRAD 95
PPP P PG PPP PG PS P L+G P
Sbjct: 858 PPPLPCTESSSSMPGLGMVPPPPPPL-PGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPL- 915
Query: 96 EGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPP----PERPRLPPAGLAGGP 151
GA P LPG+ P P +PPPPP P P P LP AG+ P
Sbjct: 916 PGAGIPPPP-------PLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPP 968
Query: 152 ----ADSAPPSPAP-APRSRPAPRPG 172
A PP P P A P P PG
Sbjct: 969 PLPGAGIPPPPPLPGAGIPPPPPLPG 994
Score = 39.3 bits (90), Expect = 0.002
Identities = 51/168 (30%), Positives = 65/168 (38%), Gaps = 25/168 (14%)
Query: 11 GRARGRPHSQVSLARRAPLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCR 70
G A G P ++ +L+ + L L P PP PG P + P PAA+
Sbjct: 261 GEAPGSPDTEQALSALSDLP--ESLAAEPREPQQPPSPGGLPVSEAPSLPAAQP------ 312
Query: 71 ARCPSPAAGGLRGPWTAAPGRQRAD---EGAAAARPERQ----RVWARRLPGSAAAPAPG 123
A SP++ P A PG + A GA E + R PG AP G
Sbjct: 313 AAKDSPSSTAFPFP-EAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVG 371
Query: 124 RDA-LRLPPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRS-RPAP 169
DA RL P + P P A S P SPAP+ R +P P
Sbjct: 372 EDAPQRLGEEPEEEAQGPDAPAAA-------SLPGSPAPSQRCFKPYP 412
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 55.5 bits (132), Expect = 2e-08
Identities = 50/172 (29%), Positives = 59/172 (34%), Gaps = 49/172 (28%)
Query: 33 PGLRDPPPPRPAPP----------------RPGEEPGNRHPPPPAARTHPGSCRARCPSP 76
PG+ PP P PP PG + HP PP HPG + +
Sbjct: 255 PGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHH 314
Query: 77 AAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPP- 135
GL P PG G RP PG P PG + +PP PP
Sbjct: 315 GPHGLGHPHAGPPG----SGGQPPPRPP---------PG---MPHPGPPPMGMPPRGPPF 358
Query: 136 --PPERP-RLPPAGLAGGP------ADSAPPSP-------APAPRSRPAPRP 171
P P +PP G+ G P + PP P P P RP PRP
Sbjct: 359 GSPMGHPGPMPPHGMRGPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTPRP 410
Score = 50.1 bits (118), Expect = 1e-06
Identities = 58/206 (28%), Positives = 64/206 (31%), Gaps = 41/206 (19%)
Query: 5 ASGRRQGRARGR---PHSQVSLARRAPLMFGPGLRDPPPPRPAP-----------PRPGE 50
+ G R G A R + +S A R +F D PPP AP P PG
Sbjct: 182 SKGERHGSAAERLLAAQNPLSQADRPHQLFA----DAPPPPSAPNPVVSSLGSGLPPPGM 237
Query: 51 EPGNRHPPP--PAARTHPGSCRARCPSPAAGGLRG---PWTAAPGRQRADEGAAAARP-- 103
P PPP P PG A P P G G P PG G + P
Sbjct: 238 PPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFP 297
Query: 104 --------ERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPERPRL--PPAGLA----- 148
Q A P P G PPP PPP P PP G+
Sbjct: 298 PGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPP 357
Query: 149 -GGPADSAPPSPAPAPRSRPAPRPGH 173
G P P P R P P H
Sbjct: 358 FGSPMGHPGPMPPHGMRGPPPLMPPH 383
Score = 49.7 bits (117), Expect = 1e-06
Identities = 50/152 (32%), Positives = 54/152 (35%), Gaps = 45/152 (29%)
Query: 15 GRPH---SQVSLARRAPLMFG------PGLRDPPPPRPAP--PRPGEEPGN---RHPPPP 60
G PH SQ+ LA P G PG PPPRP P P PG P R PP
Sbjct: 300 GMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFG 359
Query: 61 AARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAP 120
+ HPG P P G +RGP P G P
Sbjct: 360 SPMGHPG------PMPPHG-MRGPPPLMPPH-----------------------GYTGPP 389
Query: 121 APGRDAL-RLPPPPPPPPERPRLPPAGLAGGP 151
P R P PPP P RP +PP G GP
Sbjct: 390 RPPPYGYQRGPLPPPRPTPRPPVPPRGPLRGP 421
>gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo
sapiens]
Length = 756
Score = 55.1 bits (131), Expect = 3e-08
Identities = 49/136 (36%), Positives = 57/136 (41%), Gaps = 25/136 (18%)
Query: 38 PP--PPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRAD 95
PP PP PP P EPG P AA+ PG R +P GP +PG
Sbjct: 5 PPASPPGSEPPGPDPEPGG-PDGPGAAQLAPGPAELRLGAPVG----GPDPQSPGLDEPA 59
Query: 96 EGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPERPRLPPAGLAGGPADSA 155
GAAA R W +A PAPG + P P PP PR P G ++
Sbjct: 60 PGAAADGGAR---W-------SAGPAPGLEGGPRDPGPSAPP--PRSGPRGQL-----AS 102
Query: 156 PPSPAPAPRSRPAPRP 171
P +P P PRS AP P
Sbjct: 103 PDAPGPGPRSE-APLP 117
Score = 31.2 bits (69), Expect = 0.48
Identities = 36/127 (28%), Positives = 46/127 (36%), Gaps = 18/127 (14%)
Query: 34 GLRDP----PPPRP-------APPRPGEEPGNRHPPPP-----AARTHPGSCR-ARCPSP 76
G RDP PPPR +P PG P + P P + P C A CP
Sbjct: 81 GPRDPGPSAPPPRSGPRGQLASPDAPGPGPRSEAPLPELDPLFSWTEEPEECGPASCPES 140
Query: 77 AAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPP 136
A L+G ++ R D + P + + PGS P+ LP P
Sbjct: 141 APFRLQGSSSSHRARGEVDVFSPFPAPTAGELALEQGPGSPPQPSDLSQTHPLPSEPVGS 200
Query: 137 PE-RPRL 142
E PRL
Sbjct: 201 QEDGPRL 207
Score = 27.7 bits (60), Expect = 5.3
Identities = 25/63 (39%), Positives = 29/63 (46%), Gaps = 13/63 (20%)
Query: 116 SAAAPA--PGRDALRLPPPPPPPPERPRLPPAG-LAGGPAD---SAP---PSPAPAPRSR 166
++A PA PG + PP P P P P P A LA GPA+ AP P P
Sbjct: 2 ASAPPASPPGSE----PPGPDPEPGGPDGPGAAQLAPGPAELRLGAPVGGPDPQSPGLDE 57
Query: 167 PAP 169
PAP
Sbjct: 58 PAP 60
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 55.1 bits (131), Expect = 3e-08
Identities = 46/156 (29%), Positives = 54/156 (34%), Gaps = 50/156 (32%)
Query: 24 ARRAPLMFGPGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRG 83
AR AP P + PPPP P PP P P PP P P++ ++
Sbjct: 162 ARTAPPR--PNVPAPPPPTPPPPPP--------PLPP-------------PLPSSSPIKT 198
Query: 84 PWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPERPRLP 143
P + PG G+ AP PPPPPPPP P LP
Sbjct: 199 PLVSPPGPLTK--------------------GNLPVVAPPVPCAPPPPPPPPPPTPPPLP 238
Query: 144 PAGLAGGPADS-------APPSPAPAPRSRPAPRPG 172
PA + A PP P P P P PG
Sbjct: 239 PASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPG 274
Score = 47.0 bits (110), Expect = 8e-06
Identities = 47/137 (34%), Positives = 51/137 (37%), Gaps = 12/137 (8%)
Query: 38 PPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCP--SPAAGGLRGPW-TAAPGRQRA 94
P P PAPP P P PPPP P S + P SP +G AP A
Sbjct: 167 PRPNVPAPPPPTPPP----PPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCA 222
Query: 95 DEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPERPRLPPAGLAGGPADS 154
P S A P L LPP PPP P LPP G G A+
Sbjct: 223 PPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPP---LPLLPPCGYPGLKAE- 278
Query: 155 APPSPAPAPRSRPAPRP 171
P SPA + PAP P
Sbjct: 279 -PASPAQDAQEPPAPPP 294
Score = 45.4 bits (106), Expect = 2e-05
Identities = 42/140 (30%), Positives = 51/140 (36%), Gaps = 6/140 (4%)
Query: 38 PPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADEG 97
PPPP P P P ++ P A H P G G A P D
Sbjct: 229 PPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPG-LKAEPASPAQDAQ 287
Query: 98 AAAARPERQRVWARRLPGSA--AAPAPG-RDALRLPPPPPPPPERPRLPP--AGLAGGPA 152
A P +A P ++ A P PG + PPP PP + PP AG PA
Sbjct: 288 EPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPA 347
Query: 153 DSAPPSPAPAPRSRPAPRPG 172
APP P + + RPG
Sbjct: 348 PPAPPGSQPFLQKKRHGRPG 367
Score = 44.7 bits (104), Expect = 4e-05
Identities = 44/162 (27%), Positives = 51/162 (31%), Gaps = 53/162 (32%)
Query: 33 PGLRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGPWTAAPGRQ 92
P LR A + G+ PG+R P P R P+ G P A+P
Sbjct: 107 PVLRPAGQRDVAGGKTGQGPGSRAPSP------------RLPNKTISGPLIP-PASPRLG 153
Query: 93 RADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPERPRLPP-------- 144
E AAR AP R + PPPP PPP P LPP
Sbjct: 154 NTSEAHGAART-----------------APPRPNVPAPPPPTPPPPPPPLPPPLPSSSPI 196
Query: 145 ---------------AGLAGGPADSAPPSPAPAPRSRPAPRP 171
+ P APP P P P P P P
Sbjct: 197 KTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLP 238
Score = 44.7 bits (104), Expect = 4e-05
Identities = 51/160 (31%), Positives = 61/160 (38%), Gaps = 23/160 (14%)
Query: 26 RAPLMFGPG-LRDPPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCPSPAAGGLRGP 84
+ PL+ PG L P APP P P PPPP T P P P A L
Sbjct: 197 KTPLVSPPGPLTKGNLPVVAPPVPCAPPP---PPPPPPPTPP-------PLPPASVLSDK 246
Query: 85 WTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPA-PGRDALRLPPPPPP-PPERPRL 142
A Q A P + PG A PA P +DA P PPPP PP
Sbjct: 247 ---AVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCS 303
Query: 143 PPAGLAGGP-------ADSAPPSPAPAPRSRPAPRPGHAQ 175
P A L P +++ PP P +P + P+ AQ
Sbjct: 304 PRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQ 343
Score = 41.2 bits (95), Expect = 5e-04
Identities = 50/182 (27%), Positives = 58/182 (31%), Gaps = 52/182 (28%)
Query: 38 PPPPRPAPPRPGEEPGNRHPPPPAARTHPGSCRARCP----------------------- 74
PPPP P PP P P P P T S R P
Sbjct: 7 PPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQIN 66
Query: 75 ---SPAAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAPGRDAL---- 127
+P +G T G A+ A+ P ++A P PA RD
Sbjct: 67 DRSAPQIESSKG--TNKEGGGSANTRGASTPPTLGDLFAGGFP--VLRPAGQRDVAGGKT 122
Query: 128 ------RLPPPPPP---------PPERPRLPPAGLAGGPADSAPPS---PAPAPRSRPAP 169
R P P P PP PRL A G A +APP PAP P + P P
Sbjct: 123 GQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPP 182
Query: 170 RP 171
P
Sbjct: 183 PP 184
Score = 39.3 bits (90), Expect = 0.002
Identities = 41/136 (30%), Positives = 49/136 (36%), Gaps = 28/136 (20%)
Query: 33 PGLRDPPPPRPAPPRPGEEPGNRHPP-PPAARTHPGSCRARCPSPAAGGLRGPWTAAPGR 91
PGL+ P +P + +EP PP PP A P RA P+P PG
Sbjct: 273 PGLKAEPA---SPAQDAQEPPAPPPPLPPYASCSP---RASLPAPPL----------PGV 316
Query: 92 QRADEGAAAARPERQRVWARRLPGSAAAPAPGRDALRLPPPPPPPPERPRLPPA--GLAG 149
+ E P+ S AP A LP PP PP +P L G G
Sbjct: 317 NSSSETPPPLPPKSP---------SFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPG 367
Query: 150 GPADSAPPSPAPAPRS 165
P PAP RS
Sbjct: 368 AGGGKLNPPPAPPARS 383
Score = 38.5 bits (88), Expect = 0.003
Identities = 19/44 (43%), Positives = 20/44 (45%)
Query: 131 PPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRPAPRPGHA 174
PPPPPPP P PP G P SAPP R A G +
Sbjct: 4 PPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRS 47
Score = 35.0 bits (79), Expect = 0.033
Identities = 16/35 (45%), Positives = 18/35 (51%), Gaps = 6/35 (17%)
Query: 129 LPPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAP 163
+P PPPPPP P PP P + PP P AP
Sbjct: 1 MPVPPPPPPPLPPPPP------PLGAPPPPPPSAP 29
Score = 29.3 bits (64), Expect = 1.8
Identities = 14/29 (48%), Positives = 14/29 (48%), Gaps = 4/29 (13%)
Query: 120 PAPGRDALRLPPPPPP----PPERPRLPP 144
P P LPPPPPP PP P PP
Sbjct: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPP 30
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.137 0.459
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,471,621
Number of Sequences: 37866
Number of extensions: 1384681
Number of successful extensions: 45018
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1622
Number of HSP's successfully gapped in prelim test: 2115
Number of HSP's that attempted gapping in prelim test: 9583
Number of HSP's gapped (non-prelim): 18343
length of query: 175
length of database: 18,247,518
effective HSP length: 95
effective length of query: 80
effective length of database: 14,650,248
effective search space: 1172019840
effective search space used: 1172019840
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.