Guide to the Human Genome
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Search of human proteins with 194097341

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194097341 period 1 [Homo sapiens]
         (1290 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194097341 period 1 [Homo sapiens]                                 2618   0.0  
gi|12707562 period 2 [Homo sapiens]                                   910   0.0  
gi|8567388 period 3 [Homo sapiens]                                    625   e-179
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    80   2e-14
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    79   2e-14
gi|71852582 aryl hydrocarbon receptor nuclear translocator-like ...    76   2e-13
gi|71852580 aryl hydrocarbon receptor nuclear translocator-like ...    76   2e-13
gi|42716311 aryl hydrocarbon receptor nuclear translocator-like ...    76   2e-13
gi|30795242 aryl hydrocarbon receptor nuclear translocator isofo...    75   3e-13
gi|4502231 aryl hydrocarbon receptor nuclear translocator isofor...    75   3e-13
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    74   7e-13
gi|31745180 aryl hydrocarbon receptor nuclear translocator-like ...    72   3e-12
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    72   3e-12
gi|68303555 aryl hydrocarbon receptor nuclear translocator 2 [Ho...    69   3e-11
gi|195963410 MEF2 activating motif and SAP domain containing tra...    68   5e-11
gi|32698970 MEF2 activating motif and SAP domain containing tran...    68   5e-11
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          68   5e-11
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          68   5e-11
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          68   5e-11
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    67   8e-11
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    67   1e-10
gi|9945318 MAX binding protein [Homo sapiens]                          67   1e-10
gi|163965366 nascent polypeptide-associated complex alpha subuni...    67   1e-10
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]         66   2e-10
gi|47132519 Ras association and pleckstrin homology domains 1 is...    65   5e-10
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    64   1e-09
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       64   1e-09
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         64   1e-09
gi|153792074 proline rich 12 [Homo sapiens]                            63   2e-09
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    63   2e-09

>gi|194097341 period 1 [Homo sapiens]
          Length = 1290

 Score = 2618 bits (6785), Expect = 0.0
 Identities = 1290/1290 (100%), Positives = 1290/1290 (100%)

Query: 1    MSGPLEGADGGGDPRPGESFCPGGVPSPGPPQHRPCPGPSLADDTDANSNGSSGNESNGH 60
            MSGPLEGADGGGDPRPGESFCPGGVPSPGPPQHRPCPGPSLADDTDANSNGSSGNESNGH
Sbjct: 1    MSGPLEGADGGGDPRPGESFCPGGVPSPGPPQHRPCPGPSLADDTDANSNGSSGNESNGH 60

Query: 61   ESRGASQRSSHSSSSGNGKDSALLETTESSKSTNSQSPSPPSSSIAYSLLSASSEQDNPS 120
            ESRGASQRSSHSSSSGNGKDSALLETTESSKSTNSQSPSPPSSSIAYSLLSASSEQDNPS
Sbjct: 61   ESRGASQRSSHSSSSGNGKDSALLETTESSKSTNSQSPSPPSSSIAYSLLSASSEQDNPS 120

Query: 121  TSGCSSEQSARARTQKELMTALRELKLRLPPERRGKGRSGTLATLQYALACVKQVQANQE 180
            TSGCSSEQSARARTQKELMTALRELKLRLPPERRGKGRSGTLATLQYALACVKQVQANQE
Sbjct: 121  TSGCSSEQSARARTQKELMTALRELKLRLPPERRGKGRSGTLATLQYALACVKQVQANQE 180

Query: 181  YYQQWSLEEGEPCSMDMSTYTLEELEHITSEYTLQNQDTFSVAVSFLTGRIVYISEQAAV 240
            YYQQWSLEEGEPCSMDMSTYTLEELEHITSEYTLQNQDTFSVAVSFLTGRIVYISEQAAV
Sbjct: 181  YYQQWSLEEGEPCSMDMSTYTLEELEHITSEYTLQNQDTFSVAVSFLTGRIVYISEQAAV 240

Query: 241  LLRCKRDVFRGTRFSELLAPQDVGVFYGSTAPSRLPTWGTGASAGSGLRDFTQEKSVFCR 300
            LLRCKRDVFRGTRFSELLAPQDVGVFYGSTAPSRLPTWGTGASAGSGLRDFTQEKSVFCR
Sbjct: 241  LLRCKRDVFRGTRFSELLAPQDVGVFYGSTAPSRLPTWGTGASAGSGLRDFTQEKSVFCR 300

Query: 301  IRGGPDRDPGPRYQPFRLTPYVTKIRVSDGAPAQPCCLLIAERIHSGYEAPRIPPDKRIF 360
            IRGGPDRDPGPRYQPFRLTPYVTKIRVSDGAPAQPCCLLIAERIHSGYEAPRIPPDKRIF
Sbjct: 301  IRGGPDRDPGPRYQPFRLTPYVTKIRVSDGAPAQPCCLLIAERIHSGYEAPRIPPDKRIF 360

Query: 361  TTRHTPSCLFQDVDERAAPLLGYLPQDLLGAPVLLFLHPEDRPLMLAIHKKILQLAGQPF 420
            TTRHTPSCLFQDVDERAAPLLGYLPQDLLGAPVLLFLHPEDRPLMLAIHKKILQLAGQPF
Sbjct: 361  TTRHTPSCLFQDVDERAAPLLGYLPQDLLGAPVLLFLHPEDRPLMLAIHKKILQLAGQPF 420

Query: 421  DHSPIRFCARNGEYVTMDTSWAGFVHPWSRKVAFVLGRHKVRTAPLNEDVFTPPAPSPAP 480
            DHSPIRFCARNGEYVTMDTSWAGFVHPWSRKVAFVLGRHKVRTAPLNEDVFTPPAPSPAP
Sbjct: 421  DHSPIRFCARNGEYVTMDTSWAGFVHPWSRKVAFVLGRHKVRTAPLNEDVFTPPAPSPAP 480

Query: 481  SLDTDIQELSEQIHRLLLQPVHSPSPTGLCGVGAVTSPGPLHSPGSSSDSNGGDAEGPGP 540
            SLDTDIQELSEQIHRLLLQPVHSPSPTGLCGVGAVTSPGPLHSPGSSSDSNGGDAEGPGP
Sbjct: 481  SLDTDIQELSEQIHRLLLQPVHSPSPTGLCGVGAVTSPGPLHSPGSSSDSNGGDAEGPGP 540

Query: 541  PAPVTFQQICKDVHLVKHQGQQLFIESRARPQSRPRLPATGTFKAKALPCQSPDPELEAG 600
            PAPVTFQQICKDVHLVKHQGQQLFIESRARPQSRPRLPATGTFKAKALPCQSPDPELEAG
Sbjct: 541  PAPVTFQQICKDVHLVKHQGQQLFIESRARPQSRPRLPATGTFKAKALPCQSPDPELEAG 600

Query: 601  SAPVQAPLALVPEEAERKEASSCSYQQINCLDSILRYLESCNLPSTTKRKCASSSSYTTS 660
            SAPVQAPLALVPEEAERKEASSCSYQQINCLDSILRYLESCNLPSTTKRKCASSSSYTTS
Sbjct: 601  SAPVQAPLALVPEEAERKEASSCSYQQINCLDSILRYLESCNLPSTTKRKCASSSSYTTS 660

Query: 661  SASDDDRQRTGPVSVGTKKDPPSAALSGEGATPRKEPVVGGTLSPLALANKAESVVSVTS 720
            SASDDDRQRTGPVSVGTKKDPPSAALSGEGATPRKEPVVGGTLSPLALANKAESVVSVTS
Sbjct: 661  SASDDDRQRTGPVSVGTKKDPPSAALSGEGATPRKEPVVGGTLSPLALANKAESVVSVTS 720

Query: 721  QCSFSSTIVHVGDKKPPESDIIMMEDLPGLAPGPAPSPAPSPTVAPDPAPDAYRPVGLTK 780
            QCSFSSTIVHVGDKKPPESDIIMMEDLPGLAPGPAPSPAPSPTVAPDPAPDAYRPVGLTK
Sbjct: 721  QCSFSSTIVHVGDKKPPESDIIMMEDLPGLAPGPAPSPAPSPTVAPDPAPDAYRPVGLTK 780

Query: 781  AVLSLHTQKEEQAFLSRFRDLGRLRGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAK 840
            AVLSLHTQKEEQAFLSRFRDLGRLRGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAK
Sbjct: 781  AVLSLHTQKEEQAFLSRFRDLGRLRGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAK 840

Query: 841  RSRHHQNPRAEAPCYVSHPSPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPP 900
            RSRHHQNPRAEAPCYVSHPSPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPP
Sbjct: 841  RSRHHQNPRAEAPCYVSHPSPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPP 900

Query: 901  APTSVPPAAFPAPLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLPA 960
            APTSVPPAAFPAPLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLPA
Sbjct: 901  APTSVPPAAFPAPLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLPA 960

Query: 961  LAPSPPHRPDSPLFNSRCSSPLQLNLLQLEELPRAEGAAVAGGPGSSAGPPPPSAEAAEP 1020
            LAPSPPHRPDSPLFNSRCSSPLQLNLLQLEELPRAEGAAVAGGPGSSAGPPPPSAEAAEP
Sbjct: 961  LAPSPPHRPDSPLFNSRCSSPLQLNLLQLEELPRAEGAAVAGGPGSSAGPPPPSAEAAEP 1020

Query: 1021 EARLAEVTESSNQDALSGSSDLLELLLQEDSRSGTGSAASGSLGSGLGSGSGSGSHEGGS 1080
            EARLAEVTESSNQDALSGSSDLLELLLQEDSRSGTGSAASGSLGSGLGSGSGSGSHEGGS
Sbjct: 1021 EARLAEVTESSNQDALSGSSDLLELLLQEDSRSGTGSAASGSLGSGLGSGSGSGSHEGGS 1080

Query: 1081 TSASITRSSQSSHTSKYFGSIDSSEAEAGAARGGAEPGDQVIKYVLQDPIWLLMANADQR 1140
            TSASITRSSQSSHTSKYFGSIDSSEAEAGAARGGAEPGDQVIKYVLQDPIWLLMANADQR
Sbjct: 1081 TSASITRSSQSSHTSKYFGSIDSSEAEAGAARGGAEPGDQVIKYVLQDPIWLLMANADQR 1140

Query: 1141 VMMTYQVPSRDMTSVLKQDRERLRAMQKQQPRFSEDQRRELGAVHSWVRKGQLPRALDVM 1200
            VMMTYQVPSRDMTSVLKQDRERLRAMQKQQPRFSEDQRRELGAVHSWVRKGQLPRALDVM
Sbjct: 1141 VMMTYQVPSRDMTSVLKQDRERLRAMQKQQPRFSEDQRRELGAVHSWVRKGQLPRALDVM 1200

Query: 1201 ACVDCGSSTQDPGHPDDPLFSELDGLGLEPMEEGGGEQGSSGGGSGEGEGCEEAQGGAKA 1260
            ACVDCGSSTQDPGHPDDPLFSELDGLGLEPMEEGGGEQGSSGGGSGEGEGCEEAQGGAKA
Sbjct: 1201 ACVDCGSSTQDPGHPDDPLFSELDGLGLEPMEEGGGEQGSSGGGSGEGEGCEEAQGGAKA 1260

Query: 1261 SSSQDLAMEEEEEGRSSSSPALPTAGNCTS 1290
            SSSQDLAMEEEEEGRSSSSPALPTAGNCTS
Sbjct: 1261 SSSQDLAMEEEEEGRSSSSPALPTAGNCTS 1290


>gi|12707562 period 2 [Homo sapiens]
          Length = 1255

 Score =  910 bits (2352), Expect = 0.0
 Identities = 569/1297 (43%), Positives = 744/1297 (57%), Gaps = 141/1297 (10%)

Query: 26   PSPGPPQHRPC-PGPS---LADDTDANSNGSSGNESNGHESRGASQRSSHSSSSGNGKDS 81
            PSP  P   P  P PS   L +D D +S GSSG+E+N + S G   + S    SG  K+ 
Sbjct: 9    PSPSNPTKEPVEPQPSQVPLQEDVDMSS-GSSGHETNENCSTGRDSQGSDCDDSG--KEL 65

Query: 82   ALLETTESSKSTNSQSPSPPSSSIAYSLLSASSEQDNPSTSGCSSEQSARARTQKELMTA 141
             +L     ++    QSP        +SL+ A SE  NPSTSGCSS+QS++  T KEL+  
Sbjct: 66   GMLVEPPDAR----QSPD------TFSLMMAKSEH-NPSTSGCSSDQSSKVDTHKELIKT 114

Query: 142  LRELKLRLPPERRGKGRSGTLATLQYALACVKQVQANQEYYQQWSLEEGEPCSMDMSTYT 201
            L+ELK+ LP +++ KG++ TLATL+YAL  VKQV+AN+EYYQ     EG PC  D+ +YT
Sbjct: 115  LKELKVHLPADKKAKGKASTLATLKYALRSVKQVKANEEYYQLLMSSEGHPCGADVPSYT 174

Query: 202  LEELEHITSEYTLQNQDTFSVAVSFLTGRIVYISEQAAVLLRCKRDVFRGTRFSELLAPQ 261
            +EE+E +TSE+ ++N D F+VAVS ++G+I+YIS+Q A +  CKRD F   +F E LAP 
Sbjct: 175  VEEMESVTSEHIVKNADMFAVAVSLVSGKILYISDQVASIFHCKRDAFSDAKFVEFLAPH 234

Query: 262  DVGVFYGSTAPSRLPTWGTGASAGSGLRDFTQEKSVFCRIRGGPDRDPGPRYQPFRLTPY 321
            DVGVF+  T+P +LP W   + A S  ++  +EKS FCR+      +   RY PFR+TPY
Sbjct: 235  DVGVFHSFTSPYKLPLWSMCSGADSFTQECMEEKSFFCRVSVRKSHENEIRYHPFRMTPY 294

Query: 322  VTKIRVSDGAPAQPCCLLIAERIHSGYEAPRIPPDKRIFTTRHTPSCLFQDVDERAAPLL 381
            + K+R   GA +Q CCLL+AER+HSGYEAPRIPP+KRIFTT HTP+CLFQDVDERA PLL
Sbjct: 295  LVKVRDQQGAESQLCCLLLAERVHSGYEAPRIPPEKRIFTTTHTPNCLFQDVDERAVPLL 354

Query: 382  GYLPQDLLGAPVLLFLHPEDRPLMLAIHKKILQLAGQPFDHSPIRFCARNGEYVTMDTSW 441
            GYLPQDL+  PVL+ LHP DRPLMLAIHKKILQ  GQPFD+SPIRF ARNGEY+T+DTSW
Sbjct: 355  GYLPQDLIETPVLVQLHPSDRPLMLAIHKKILQSGGQPFDYSPIRFRARNGEYITLDTSW 414

Query: 442  AGFVHPWSRKVAFVLGRHKVRTAPLNEDVFTPPAPSPAPSLDTDIQELSEQIHRLLLQPV 501
            + F++PWSRK++F++GRHKVR  PLNEDVF     +   +L   IQEL+EQIHRLLLQPV
Sbjct: 415  SSFINPWSRKISFIIGRHKVRVGPLNEDVFAAHPCTEEKALHPSIQELTEQIHRLLLQPV 474

Query: 502  HSPSPTGLCGVGAVTSPGPLHSPGSSSDSNGGDAEGPGPPAPVTFQQICKDVHLVKHQGQ 561
                 +G   +G+  S   L S  SSSDSNG +       +     +ICK+ +  K++  
Sbjct: 475  PHSGSSGYGSLGSNGSHEHLMSQTSSSDSNGHE------DSRRRRAEICKNGNKTKNRSH 528

Query: 562  QLFIESRARPQSRPRLPATGTFKAKALPCQSPDPELEAGSAPVQAPLALVPEEAERKEAS 621
                    + +S   +      + KA+P       +E  S  V       PEE   K   
Sbjct: 529  YSHESGEQKKKSVTEMQTNPPAEKKAVPA------MEKDSLGVS-----FPEELACKNQP 577

Query: 622  SCSYQQINCLDSILRYLESCNLPSTTKRKCASSSSYTTSSASDDDRQRTGPVSVGTKKDP 681
            +CSYQQI+CLDS++RYLESCN  +T KRKC   ++     +SD  +    P     + +P
Sbjct: 578  TCSYQQISCLDSVIRYLESCNEAATLKRKCEFPANVPALRSSDKRKATVSPGPHAGEAEP 637

Query: 682  PSAALSGEGATPRKEPVVGGTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPESDI 741
            PS   S  G        VG  L+ LAL  KAESV S+TSQCS+SSTIVHVGDKK P+ ++
Sbjct: 638  PSRVNSRTG--------VGTHLTSLALPGKAESVASLTSQCSYSSTIVHVGDKK-PQPEL 688

Query: 742  IMMEDLPGLAPGP-----APSPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLS 796
             M+ED    A GP        PA +  ++ +  P  ++ +GLTK VL+ HTQKEEQ+FL 
Sbjct: 689  EMVED---AASGPESLDCLAGPALACGLSQEKEP--FKKLGLTKEVLAAHTQKEEQSFLQ 743

Query: 797  RFRDLGRL---------------RGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKR 841
            +F+++ +L               +G  S  TAP      G         +    +SK  +
Sbjct: 744  KFKEIRKLSIFQSHCHYYLQERSKGQPSERTAPGLRNTSGIDSPWKKTGKNRKLKSKRVK 803

Query: 842  SRHHQNPRAEAPCYVSHPSPV--------PPSTPWPTPPATTPFPA-VVQPYPLPVFSPR 892
             R             + P  V        P  T   + PA  PFPA V   Y LPVF P 
Sbjct: 804  PRDSSESTGSGGPVSARPPLVGLNATAWSPSDTSQSSCPA-VPFPAPVPAAYSLPVF-PA 861

Query: 893  GGPQPLPPAPT-----------------SVPPAAFPAPLVTPMVALVLPNYLFP--TPS- 932
             G    PPAP                  +V P  FPAPL  P++A +LP+Y FP  TP+ 
Sbjct: 862  PGTVAAPPAPPHASFTVPAVPVDLQHQFAVQPPPFPAPL-APVMAFMLPSYSFPSGTPNL 920

Query: 933  ------------SYPYGALQTPAEGPPTPASHSPSPSLPALAP----SPPH---RPDSPL 973
                        S+P    +  +   P   S +  P  P   P    +PP    R   PL
Sbjct: 921  PQAFFPSQPQFPSHPTLTSEMASASQPEFPSRTSIPRQPCACPATRATPPSAMGRASPPL 980

Query: 974  FNSRCSSPLQLNLLQLEELPRAEGAAVAGGPGSS------AGPPPPSAEAAEPEARLA-- 1025
            F SR SSPLQLNLLQLEE P   G    G  G++      A   P ++   +P+A L   
Sbjct: 981  FQSRSSSPLQLNLLQLEEAPEG-GTGAMGTTGATETAAVGADCKPGTSRDQQPKAPLTRD 1039

Query: 1026 EVTESSNQDALSGSSDLLELLLQEDSRSGTGSAASGSLGSGLGSGSGSGSHEGGSTSASI 1085
            E +++ N DALS SS LL LLL ED  S +GSAAS SLGSG           G   S S 
Sbjct: 1040 EPSDTQNSDALSTSSGLLNLLLNEDLCSASGSAASESLGSG---------SLGCDASPSG 1090

Query: 1086 TRSSQSSHTSKYFGSIDSSEAEAGAARG-GAEPGDQVIKYVLQDPIWLLMANADQRVMMT 1144
              SS +SHTSKYFGSIDSSE    A    G E  +  IK VLQDPIWLLMA+AD  VMMT
Sbjct: 1091 AGSSDTSHTSKYFGSIDSSENNHKAKMNTGMEESEHFIKCVLQDPIWLLMADADSSVMMT 1150

Query: 1145 YQVPSRDMTSVLKQDRERLRAMQKQQPRFSEDQRRELGAVHSWVRKGQLPRALDVMACVD 1204
            YQ+PSR++ +VLK+DRE+L+ +QK QPRF+E Q++EL  VH W++ G LP A+DV  CV 
Sbjct: 1151 YQLPSRNLEAVLKEDREKLKLLQKLQPRFTESQKQELREVHQWMQTGGLPAAIDVAECVY 1210

Query: 1205 CGSSTQDPGHPDDPLFSELDGLGLEPMEEGGGEQGSS 1241
            C    ++ G+   P   ++  LGL  + +   ++  S
Sbjct: 1211 C--ENKEKGNICIPYEEDIPSLGLSEVSDTKEDENGS 1245


>gi|8567388 period 3 [Homo sapiens]
          Length = 1201

 Score =  625 bits (1613), Expect = e-179
 Identities = 439/1185 (37%), Positives = 609/1185 (51%), Gaps = 137/1185 (11%)

Query: 126  SEQSARARTQKELMTALRELKLRLPPERRGKGRSGTLATLQYALACVKQVQANQEYYQQW 185
            SEQ  R R  +EL+  ++E+K   P ERR K    TL  L YAL CV  VQAN E++Q  
Sbjct: 43   SEQQDRNRVSEELIMVVQEMKKYFPSERRNK--PSTLDALNYALRCVHSVQANSEFFQIL 100

Query: 186  SLEEGEPCSMDMSTYTLEELEHITSEYTLQNQDTFSVAVSFLTGRIVYISEQAAVLLRCK 245
            S + G P   D+S Y+LEEL  I SE+T +N DTF    SFL+GR+V+ISEQAA++L  K
Sbjct: 101  S-QNGAP-QADVSMYSLEELATIASEHTSKNTDTFVAVFSFLSGRLVHISEQAALILNRK 158

Query: 246  RDVFRGTRFSELLAPQDVGVFYGSTAPSRLPTWGTGASAGSGLRDFTQEKSVFCRIRGGP 305
            +DV   + F +LLAPQD+ VFY  TA ++LP W       +   +    K  FCRIRGG 
Sbjct: 159  KDVLASSHFVDLLAPQDMRVFYAHTARAQLPFWNNWTQRAARY-ECAPVKPFFCRIRGGE 217

Query: 306  DRDPGPRYQPFRLTPYVTKIR--VSDGAPAQPCCLLIAERIHSGYEAPRIPPDKRIFTTR 363
            DR     + PFR+ PY+  +         ++PCCL + E+IHSGYEAPRIP +KRIFTT 
Sbjct: 218  DRKQEKCHSPFRIIPYLIHVHHPAQPELESEPCCLTVVEKIHSGYEAPRIPVNKRIFTTT 277

Query: 364  HTPSCLFQDVDERAAPLLGYLPQDLLGAPVLLFLHPEDRPLMLAIHKKILQLAGQ-PFDH 422
            HTP C+F +VDE+A PLLGYLPQDL+G  +L +LHPEDR LM+AIH+K+L+ AG  PF+H
Sbjct: 278  HTPGCVFLEVDEKAVPLLGYLPQDLIGTSILSYLHPEDRSLMVAIHQKVLKYAGHPPFEH 337

Query: 423  SPIRFCARNGEYVTMDTSWAGFVHPWSRKVAFVLGRHKVRTAPLNEDVFTPPAPSPAPSL 482
            SPIRFC +NG+Y+ +D+SW+ FV+PWSRK++F++GRHKVRT+PLNEDVF         + 
Sbjct: 338  SPIRFCTQNGDYIILDSSWSSFVNPWSRKISFIIGRHKVRTSPLNEDVFATKIKKMNDN- 396

Query: 483  DTDIQELSEQIHRLLLQPVHSPSPTGLCGVGAVTSPGPLHSPGSSSDSNGGDAEGPGPPA 542
            D DI EL EQI++LLLQPVH    +G   +G+  S   L S  SSS+++G   E      
Sbjct: 397  DKDITELQEQIYKLLLQPVHVSVSSGYGSLGSSGSQEQLVSIASSSEASGHRVE-ETKAE 455

Query: 543  PVTFQQICKDVHLVKHQGQQLFIESRARPQSRP----RLPATGTFKAKALPCQSPDPELE 598
             +T QQ+   V+ +K+ GQQL+IES  +   +P    R    G  + K     S    L+
Sbjct: 456  QMTLQQVYASVNKIKNLGQQLYIESMTKSSFKPVTGTRTEPNGGGECKTF--TSFHQTLK 513

Query: 599  AGSAPVQAPLALVPEEAERKEASSCSYQQINCLDSILRYLESCNLPSTTKRKCASSSSYT 658
              S   +      P E  R +  S SYQQINC+DS++RYL+S N+P+  KRKC S ++ T
Sbjct: 514  NNSVYTE------PCEDLRNDEHSPSYQQINCIDSVIRYLKSYNIPA-LKRKCISCTN-T 565

Query: 659  TSSASDDDRQRTGPVSVGTKKDPPSAALSG--EGATPRKE-PVVGGTL-----SPLALAN 710
            TSS+S++D+Q         K D   A  +G    A P+ E P  G ++     +P  L+ 
Sbjct: 566  TSSSSEEDKQ-------NHKADDVQALQAGLQIPAIPKSEMPTNGRSIDTGGGAPQILST 618

Query: 711  KAESVVSVTSQCSFSSTIVHVGDKKPPES--DIIMMEDLPGLAPGPAPSPAPSPTVAPDP 768
               S+ S  SQC +SSTIVHV    PPE+  D  +  +   L   PAP  +         
Sbjct: 619  AMLSLGSGISQCGYSSTIVHV---PPPETARDATLFCEPWTLNMQPAPLTS--------- 666

Query: 769  APDAYRPVGLTKAVLSLHTQKEEQAFLSRFRD--------------------LGRLRGLD 808
              + ++ VGLT AVLS HTQKEEQ ++ +FR+                        +G  
Sbjct: 667  --EEFKHVGLTAAVLSAHTQKEEQNYVDKFREKILSSPYSSYLQQESRSKAKYSYFQGDS 724

Query: 809  SSSTAPSALGERGCHHG---PAPPSRRHHCRSKAKRSRHHQNPRAEAPCYVSHPSPVPPS 865
            +S    SA   +G H     P PP           R   HQN +   P   S P    P+
Sbjct: 725  TSKQTRSAGCRKGKHKRKKLPEPPDSSSSNTGSGPRRGAHQNAQPCCPSAASSPHTSSPT 784

Query: 866  TPWPTPPATTPFPAVVQPYPLPVFSPRG-----------GPQPLPPAPTSVPPAAFPAPL 914
             P P     +  P +V  +PLP  +  G           G   LP +    P  AFP P 
Sbjct: 785  FP-PAAMVPSQAPYLVPAFPLPAATSPGREYAAPGTAPEGLHGLPLSEGLQPYPAFPFPY 843

Query: 915  VTPMVALVLPN-----YLFPTPSSYPY-GALQTPAEGPPTPASHSPSPSLPALAPSPPHR 968
            +   + + LP+      L P+    P+ GA  + A  P   ++ SP+   P    S    
Sbjct: 844  LDTFMTVFLPDPPVCPLLSPSFLPCPFLGATASSAISPSMSSAMSPTLDPPPSVTSQRRE 903

Query: 969  PDS--------PLFNSRCSSPLQLNLLQLEELPRAEGA--------------AVAGGPGS 1006
             +         P   SR SSPLQLNLLQ EE+PR   +               V G  GS
Sbjct: 904  EEKWEAQSEGHPFITSRSSSPLQLNLLQ-EEMPRPSESPDQMRRNTCPQTEYCVTGNNGS 962

Query: 1007 ----------SAGPPP------PSAEAAEPEARLAEVTESSNQDALS-GSSDLLELLLQE 1049
                      S G PP      P+A A    +   +        ALS GS  +       
Sbjct: 963  ESSPATTGALSTGSPPRENPSHPTASALSTGSPPMKNPSHPTASALSTGSPPMKNPSHPT 1022

Query: 1050 DSRSGTGSAASGSLGSGLGSGSGSGSHEGGSTSASITRSSQSSHTSKYF-GSIDSSEAEA 1108
             S    G   S +      +   +GS    S S + + +S SS +S Y   S+ SS+   
Sbjct: 1023 ASTLSMGLPPSRTPSHPTATVLSTGSPPSESPSRTGSAASGSSDSSIYLTSSVYSSKISQ 1082

Query: 1109 GAARGGAEPGDQVIKYVLQDPIWLLMANADQRVMMTYQVPSRDMTSVLKQDRERLRAMQK 1168
               +       +    V ++PIW ++    +R++MTYQVP R    VLK+D E+L +M++
Sbjct: 1083 NGQQSQDVQKKETFPNVAEEPIWRMIRQTPERILMTYQVPERVKEVVLKEDLEKLESMRQ 1142

Query: 1169 QQPRFSEDQRRELGAVHSWVRKGQLPRALDVMACVDCGSSTQDPG 1213
            QQP+FS  Q+ EL  V++W++   + + +D+ ACV C +     G
Sbjct: 1143 QQPQFSHGQKEELAKVYNWIQSQTVTQEIDIQACVTCENEDSADG 1187



 Score = 30.8 bits (68), Expect = 8.8
 Identities = 24/99 (24%), Positives = 38/99 (38%), Gaps = 2/99 (2%)

Query: 55   NESNGHESRGASQRSSHSSSSGNGKDSALLETTESSKSTNSQSPSPPSSSIAYSLLSASS 114
            +ES     R    ++ +  +  NG +S+    T  + ST S     PS   A +L + S 
Sbjct: 938  SESPDQMRRNTCPQTEYCVTGNNGSESS--PATTGALSTGSPPRENPSHPTASALSTGSP 995

Query: 115  EQDNPSTSGCSSEQSARARTQKELMTALRELKLRLPPER 153
               NPS    S+  +     +         L + LPP R
Sbjct: 996  PMKNPSHPTASALSTGSPPMKNPSHPTASTLSMGLPPSR 1034


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 855

 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 155/582 (26%), Positives = 213/582 (36%), Gaps = 71/582 (12%)

Query: 516  TSPGPLHSPGSSSDSNGGDAEGPGPPAPVTFQQICKDVHLVKHQGQQLFIESRARPQSRP 575
            TSPGP+ SPG +S        G   P P+  + +         +G+      R+   +  
Sbjct: 109  TSPGPVSSPGRAS--------GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGA 160

Query: 576  RLPATGTFKAKALPC---QSPDPELEAGSAPVQAPLALV--PEEAERKEASSCSYQQINC 630
            R   +G       P    +S     E G  P  AP A    P E  RK  SS S      
Sbjct: 161  RRDTSGPTPGTPSPAMARRSRAAGTEVG-LPRPAPSARPRPPTEGPRKSVSSASEHSTTE 219

Query: 631  LDSILRYLESCN--LPSTTKRKCASSSSYTTSSASDDDRQRTGPVSVGTKKDP--PSA-- 684
                 R   S    L     R  +SS++  +S A      R+GP + GT + P  PS   
Sbjct: 220  PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA------RSGPSARGTPRAPAHPSQPK 273

Query: 685  -----ALSGEGATPRKEPVVGGTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPES 739
                 AL     TP ++      L PL+ +  A    S   Q     T+        P S
Sbjct: 274  PKGLQALRPPQVTPPRKDAAPA-LGPLSSSPLATPSPSAALQSQAPPTL-----PATPHS 327

Query: 740  DIIMMEDLPGLAPGPAPSPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFR 799
              +  +    L   P PSP+  P++   P+P A  P   T + L   T +   +FL    
Sbjct: 328  SSLTCQLATPLPLAP-PSPSAPPSLQTLPSPPATPPSQATTS-LGSPTLQATHSFLPS-P 384

Query: 800  DLGRLRGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEAPCYVSHP 859
             L  L        AP AL        P+PP+           +   Q P A A   +  P
Sbjct: 385  PLSPLA--TPPPQAPPALALPPLQAPPSPPASPP---LSPLATPSPQAPNALAVHLLQAP 439

Query: 860  SPVPPSTPWP---TPPATTPF-PAVVQPYPLP--VFSPRGGPQPLPPAP-----TSVPPA 908
               PPS P     +PPA+ P  P+   P   P  + +P     P PPA      ++ PP 
Sbjct: 440  FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 499

Query: 909  AFPAPLVTPMVALVL-PNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLP--ALAPSP 965
              P PL  P + L   P    P  ++ P  AL +P    P  A  SPS SLP   LA  P
Sbjct: 500  QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 559

Query: 966  PHRPD---SPLFNSRCSSPLQLNLLQLEELPRAEGAAVAGGP----GSSAGPPPPSAEAA 1018
            P  P    +PL     S P    L      P         GP      + GPPPP + + 
Sbjct: 560  PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS- 618

Query: 1019 EPEARLAEVTESSNQDALSGSSDLLELLLQEDSRSGTGSAAS 1060
             P + L+    + +    S ++   E L   DS    G+AAS
Sbjct: 619  -PSSTLSGPDLAGHS---SSATSTPEELRGYDSGPEGGAAAS 656



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 137/581 (23%), Positives = 182/581 (31%), Gaps = 73/581 (12%)

Query: 472  TPPAPSPAPSLDTDIQELSEQIHRLLLQPVHSPSPTG-LCGVGAVTSPGPLHSPGSSSD- 529
            TPP    AP+L             L   P+ +PSP+  L      T P   HS   +   
Sbjct: 286  TPPRKDAAPALGP-----------LSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQL 334

Query: 530  SNGGDAEGPGPPAPVTFQQICKDVHLVKHQGQQLFIESRARPQSRPRLPATGTF--KAKA 587
            +       P P AP + Q +         Q               P L AT +F      
Sbjct: 335  ATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL--------GSPTLQATHSFLPSPPL 386

Query: 588  LPCQSPDPELEAGSA--PVQAPLALVPEEAERKEASSCSYQQINCLDSILRYLESCNLPS 645
             P  +P P+     A  P+QAP +  P        ++ S Q  N L   L        PS
Sbjct: 387  SPLATPPPQAPPALALPPLQAPPS-PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 445

Query: 646  TTKRKCASSSSYTTSSASDDDRQRTGPVSVG----TKKDPPSAALSGEGATPRKEPVVGG 701
               +   S  +    S S     +  P            PP++      ATP  +     
Sbjct: 446  PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 505

Query: 702  TLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPESDIIMMEDLPGLAPGPAP-SPAP 760
               PL LA          +               PP   +  +   P   PG AP SP+ 
Sbjct: 506  AAPPLQLAKPPPQAPPALAT--------------PP---LQALPSPPASFPGQAPFSPSA 548

Query: 761  SPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRGLDSSSTAPSALGER 820
            S  ++P   P    P  L   +L +         L   R      G D+S + P  L   
Sbjct: 549  SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR-PPTPGPDTSVSGPR-LTLA 606

Query: 821  GCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEAP----CYVSHPSPVPPSTPWPTPPATTP 876
                 P PPSR             H +     P     Y S P     ++P P       
Sbjct: 607  LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAAC 666

Query: 877  FPAVVQPYPLPVFSPRGGP-QPLPPAPTSVPPAAFPAPLV----TPMVALVLPNYLFPTP 931
             PA     P P  + RG P  PLP  P + P +A     +     P  A   P  L P P
Sbjct: 667  HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 726

Query: 932  SSYPYGALQTPAEGPPTPASHSPSPSLPALAPSPPHRPDSPLFNSRCSSPLQLNLLQLEE 991
            S    G       G     + S SP    L   P          +  +S +Q  L +   
Sbjct: 727  SPGTSGGKAAAGAG---AGASSRSPKQARLGELP--------LGALQASVVQHLLSRTLL 775

Query: 992  LPRAEGAA--VAGGP-GSSAGPPPPSAEAAEPEARLAEVTE 1029
            L  AEGAA    GGP G+  G     A AA  +A L    E
Sbjct: 776  LAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAE 816



 Score = 37.7 bits (86), Expect = 0.072
 Identities = 68/290 (23%), Positives = 92/290 (31%), Gaps = 51/290 (17%)

Query: 748  PGL-APGPAPSPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRG 806
            PGL  P P  SP P P V P     A R +G   AV                + L    G
Sbjct: 22   PGLLTPRPPGSPRPPPPVTPA----ALRVLGAAGAVGR--------------KPLAERAG 63

Query: 807  LDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEAPCYVSHPSPVPPST 866
                +T P +    G       P+R     S+   SR   + R E      + SP P S+
Sbjct: 64   GIGGATIPESAPRAG-------PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS 116

Query: 867  PWPTPPATTPFPAVVQPYPLPVFS--PRGGPQPLPP---------APTSVPPAAFPAPLV 915
            P      T P P   +   +       RG     P            TS P    P+P +
Sbjct: 117  PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176

Query: 916  TPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLPALAPSPPHRPDS---- 971
                         P P+  P    + P EGP    S +   S    +P+   RP +    
Sbjct: 177  ARRSRAAGTEVGLPRPA--PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL 234

Query: 972  --PLFNSRCSSPLQLNLLQLEELPRAEGAAVAGGPGSSAGPPPPSAEAAE 1019
              P   S  SS   L+       P   G +  G P + A P  P  +  +
Sbjct: 235  QRPASRSLSSSATPLS------SPARSGPSARGTPRAPAHPSQPKPKGLQ 278



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 53/205 (25%), Positives = 68/205 (33%), Gaps = 34/205 (16%)

Query: 836  RSKAKRSRHHQNPRAEAPCYVSHPSPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRG-- 893
            R KAK     + P A AP  ++   P PP +P P PP T        P  L V    G  
Sbjct: 5    RDKAKAGAAARTPAARAPGLLT---PRPPGSPRPPPPVT--------PAALRVLGAAGAV 53

Query: 894  GPQPLPPAPTSVPPAAFPAPLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHS 953
            G +PL      +  A  P     P           PT S+    + + PA  PP      
Sbjct: 54   GRKPLAERAGGIGGATIPES--APRAG--------PTRSAGT--SSRNPASRPPASGRGE 101

Query: 954  PSPSLPALAPSPPHRPDSPLFNSRCSSPLQLNLLQLEELPRAEGAAV---------AGGP 1004
             +P     +P P   P      +R     Q  L    E   A G A          AG  
Sbjct: 102  RAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGAR 161

Query: 1005 GSSAGPPPPSAEAAEPEARLAEVTE 1029
              ++GP P +   A      A  TE
Sbjct: 162  RDTSGPTPGTPSPAMARRSRAAGTE 186


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 134/553 (24%), Positives = 191/553 (34%), Gaps = 90/553 (16%)

Query: 516  TSPGPLHSPGSSSDSNGGDAEGPGPPAPVTFQQICKDVHLVKHQGQQLFIESRARPQSRP 575
            +S  PL SP  S  S  G    P  P+              K +G Q     +  P  + 
Sbjct: 244  SSATPLSSPARSGPSARGTPRAPAHPSQP------------KPKGLQALRPPQVTPPRKD 291

Query: 576  RLPATGTFKAKALPCQSPD-------PELEAGSAPVQAPLALVPEEAERKEASSCSYQQI 628
              PA G   +  L   SP        P  +  + P+ A L   P  A     +  S    
Sbjct: 292  AAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPS---- 347

Query: 629  NCLDSILRYLESCNLPSTTKRKCASSSSYTTSSASDDDRQRTGPVSVGTKKDPPS----- 683
                S    L++   P  T    A  S  T    +    Q   P+ V      PS     
Sbjct: 348  ---PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP 404

Query: 684  ---AALSGEGATPRKEPVVGGTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPESD 740
               A  S +  T    P +  T S L ++ + ++  S+TS    +ST        PP+S 
Sbjct: 405  SPLALSSLQATTSLGSPTLQATHSFLTMSPR-QTQASLTSPSRPAST--------PPDSP 455

Query: 741  IIMMEDLPGLAPGPAPSPAP-----SPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFL 795
                   P  AP   P+  P     SP V+P  +P    P+    ++ S   Q    + +
Sbjct: 456  -------PLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLI 508

Query: 796  SRFRDLGRLRGLDSSSTAPSALGERGCHHGP--APPSRRHHCRSKAKRSRHHQNPRAEAP 853
                +        S  T P++L      + P  APP  +    S    + H + P   AP
Sbjct: 509  MPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQ--TASAPLTTPHLETPPCPAP 566

Query: 854  CYV-SHPSPV---PPSTP---------------------WPTPPATTPFPAVVQPYPLPV 888
            C + + PSP+   PP TP                      P+PP +       Q  P   
Sbjct: 567  CPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLA 626

Query: 889  FSPRGGPQPLPPAPTSVPPAAFPAPLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPP- 947
              P   P P PPA   + P A P+P     +A+ L    F  P S P  A  +P   PP 
Sbjct: 627  LPPLQAP-PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 685

Query: 948  TPASHSPSPSLPALAPSPPHRPDSPLFNSRCSSPLQLNLLQLEELPRAEGAAVAGGPGSS 1007
            +P++  PS + P+LA  P   P SP      S P+  +     + P    A     P S 
Sbjct: 686  SPSATPPSQAPPSLAAPPLQVPPSP----PASPPMSPSATPPPQAPPPLAAPPLQVPPSP 741

Query: 1008 AGPPPPSAEAAEP 1020
               PP S  A  P
Sbjct: 742  PASPPMSPSATPP 754



 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 151/630 (23%), Positives = 218/630 (34%), Gaps = 91/630 (14%)

Query: 473  PPAPSPAPSLDT----DIQELSEQIHRLLLQPVHSPSPTGLCGVGAVTSPGPLHSPGSSS 528
            PP+PS  PSL T         S+    +   P+ +P    L  +  +  P  L SP   +
Sbjct: 345  PPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPP--SLQTIPPIQVPHSLTSPSLQA 402

Query: 529  DSNGGDAEGPGPPAPVTFQQICKDVHL-------------VKHQGQQLFIESRARPQSRP 575
                       PP+P+    +     L             +  +  Q  + S +RP S P
Sbjct: 403  -----------PPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTP 451

Query: 576  RLPATGTFKAK-ALPCQSP-DPELEAGSAPVQAPLALVPEEAERKEASSCSYQQINCLDS 633
              P +   +A  +LP   P    L    +P+ +PL + P +A    AS      ++ L  
Sbjct: 452  --PDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIM 509

Query: 634  ILRYLESCNLPSTTKRKCASSSS----YTTSSASDDDRQRTGPVSVGTKKDPP------- 682
                 +S   P + +   AS ++       S A    +  + P++    + PP       
Sbjct: 510  PPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPL 569

Query: 683  SAALSGEGATPRKEPVVGGTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPESDII 742
             A  S     P + P    T  P A      ++ S   Q   S  +  +    P     +
Sbjct: 570  QAPPSPLTTPPPETPSSIATPPPQA----PPALASPPLQGLPSPPLSPLATPPPQAPPXL 625

Query: 743  MMEDLPGLAPGPAPSPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLG 802
             +  L    P P  SP  SP   P P       V L +A  S       QA  S      
Sbjct: 626  ALPPLQA-PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 684

Query: 803  RLRGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEAPCYVSHPSPV 862
                    S AP +L        P+PP+                +P A  P     P   
Sbjct: 685  VSPSATPPSQAPPSLAAPPLQVPPSPPASPP------------MSPSATPPPQAPPPLAA 732

Query: 863  PPSTPWPTPPATTPF-PAVVQPYPLP--VFSPRGGPQPLPPAPTSVPPAAFPAPLVTPMV 919
            PP    P+PPA+ P  P+   P  +P  + +P     P PPA   + P A P P   P +
Sbjct: 733  PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL 792

Query: 920  ALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLP--ALAPSPPHRPD---SPLF 974
            A         TP   P  AL +P    P  A  SPS SLP   LA  PP  P    +PL 
Sbjct: 793  A---------TP---PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 840

Query: 975  NSRCSSPLQLNLLQLEELPRAEGAAVAGGP----GSSAGPPPPSAEAAEPEARLAEVTES 1030
                S P    L      P         GP      + GPPPP + +  P + L+    +
Sbjct: 841  QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS--PSSTLSGPDLA 898

Query: 1031 SNQDALSGSSDLLELLLQEDSRSGTGSAAS 1060
             +    S ++   E L   DS    G+AAS
Sbjct: 899  GHS---SSATSTPEELRGYDSGPEGGAAAS 925



 Score = 67.8 bits (164), Expect = 6e-11
 Identities = 146/552 (26%), Positives = 195/552 (35%), Gaps = 105/552 (19%)

Query: 516  TSPGPLHSPGSSSDSNGGDAEGPGPPAPVTFQQICKDVHLVKHQGQQLFIESRARPQSRP 575
            TSPGP+ SPG +S        G   P P+  + +         +G+      R+   +  
Sbjct: 109  TSPGPVSSPGRAS--------GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGA 160

Query: 576  RL----PATGTFKAKALPCQSPDPELEAGSAPVQAPLA--LVPEEAERKEASSCSYQQIN 629
            R     P  GT  + A+  +S     E G  P  AP A    P E  RK  SS S     
Sbjct: 161  RRDTSGPTPGT-PSPAMARRSRAAGTEVG-LPRPAPSARPRPPTEGPRKSVSSASEHSTT 218

Query: 630  CLDSILRYLESC--NLPSTTKRKCASSSSYTTSSASDDDRQRTGPVSVGTKKDP--PS-- 683
                  R   S    L     R  +SS++  +S A      R+GP + GT + P  PS  
Sbjct: 219  EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA------RSGPSARGTPRAPAHPSQP 272

Query: 684  ------AALSGEGATPRKEPVVG-GTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKP 736
                  A    +   PRK+     G LS   LA  + S           +    +    P
Sbjct: 273  KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLP 332

Query: 737  PESDIIMMEDLPGLAPGPAPSPAPSPTVAPDP--APDAYRPVGLT----KAVLSLHTQKE 790
            P     +   LP LAP P+PS  PS    P P   P +  P  +T    +A  SL T   
Sbjct: 333  PSPP--LATPLP-LAP-PSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPP 388

Query: 791  EQAFLSRFRDLGRLRGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRA 850
             Q              +  S T+PS           APPS       +A  S      +A
Sbjct: 389  IQ--------------VPHSLTSPSL---------QAPPSPLALSSLQATTSLGSPTLQA 425

Query: 851  EAPCYVSHPSPVPPSTPWPTPPATTP--FPAVVQPYPLPVFSPRGGPQPLPPAPTSVPPA 908
                    P     S   P+ PA+TP   P +  P  LP           PP  TS+ PA
Sbjct: 426  THSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPA---------SPPLQTSLSPA 476

Query: 909  AFP--APLV----------------TPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPA 950
              P  +PL                  P+ +L++P     T SS    +LQTP     TP 
Sbjct: 477  VSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPP--LETQSSLAPPSLQTPPASLTTP- 533

Query: 951  SHSPSPSLPALAPSPPHRPDSPLFNSRCSSPLQLNLLQLEELPRAEGAAVAGGPGSSAGP 1010
               P  +LP+LAP P     +PL      +P       L+  P          P S A P
Sbjct: 534  ---PLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATP 590

Query: 1011 PP--PSAEAAEP 1020
            PP  P A A+ P
Sbjct: 591  PPQAPPALASPP 602



 Score = 61.2 bits (147), Expect = 6e-09
 Identities = 106/397 (26%), Positives = 138/397 (34%), Gaps = 57/397 (14%)

Query: 669  RTGPV-SVGTKKDPPSAALSGEGATPRKEPVVGGTLSPLALANKAESVVSVTS------Q 721
            R GP  S GT    P++     G   R  P    +  P++   +A              +
Sbjct: 76   RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 135

Query: 722  CSFSSTIVHVGDKKPPESDIIMM---EDLPGLAPG-PAPSPAPSPTVA------PDPAPD 771
             S   T+      + P+   +      D  G  PG P+P+ A     A      P PAP 
Sbjct: 136  ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS 195

Query: 772  AY-RPV--GLTKAVLSL--HTQKEEQAFLSRFRDLG------RLRGLDSSST-----APS 815
            A  RP   G  K+V S   H+  E      R    G        R L SS+T     A S
Sbjct: 196  ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 255

Query: 816  ALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEAPCYVSHPSPVPPSTPWPTPPATT 875
                RG    PA PS+      +A R      PR +A          P   P  + P  T
Sbjct: 256  GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA---------APALGPLSSSPLAT 306

Query: 876  PFPAVVQPYPLPVFSPRGGPQP--LPPAPTSVPPA--AFPAPLVTPMVALVLPNYLFPTP 931
            P P+  +  P+P       P P  LPP+P    P   A P+P   P +   LP+     P
Sbjct: 307  PSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQ-TLPSPPATPP 365

Query: 932  SSYPYGALQTPAEGPPTPASHSP--------SPSLPALAPSPPHRPDSPLFNSRCSSPLQ 983
            S  P      P + PP+  +  P        SPSL A  PSP          S  S  LQ
Sbjct: 366  SQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQA-PPSPLALSSLQATTSLGSPTLQ 424

Query: 984  LNLLQLEELPRAEGAAVAGGPGSSAGPPPPSAEAAEP 1020
                 L   PR   A++   P   A  PP S     P
Sbjct: 425  ATHSFLTMSPRQTQASLT-SPSRPASTPPDSPPLQAP 460



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 79/326 (24%), Positives = 105/326 (32%), Gaps = 53/326 (16%)

Query: 748  PGL-APGPAPSPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRG 806
            PGL  P P  SP P P V     P A R +G   AV                + L    G
Sbjct: 22   PGLLTPRPPGSPRPPPPV----TPAALRVLGAAGAV--------------GRKPLAERAG 63

Query: 807  LDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEAPCYVSHPSPVPPST 866
                +T P +    G       P+R     S+   SR   + R E      + SP P S+
Sbjct: 64   GIGGATIPESAPRAG-------PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS 116

Query: 867  PWPTPPATTPFPAVVQPYPLPVFS--PRGGPQPLPP---------APTSVPPAAFPAPLV 915
            P      T P P   +   +       RG     P            TS P    P+P +
Sbjct: 117  PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176

Query: 916  TPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLPALAPSPPHRPDS---- 971
                         P P+  P    + P EGP    S +   S    +P+   RP +    
Sbjct: 177  ARRSRAAGTEVGLPRPA--PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL 234

Query: 972  --PLFNSRCSSPLQLNLLQLEELPRAEGAAVAGGPGSSAGPPPPSAEAAEPEARLAEVTE 1029
              P   S  SS   L+       P   G +  G P + A P  P  +  +   R  +VT 
Sbjct: 235  QRPASRSLSSSATPLS------SPARSGPSARGTPRAPAHPSQPKPKGLQ-ALRPPQVT- 286

Query: 1030 SSNQDALSGSSDLLELLLQEDSRSGT 1055
               +DA      L    L   S SGT
Sbjct: 287  PPRKDAAPALGPLSSSPLATPSPSGT 312



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 53/205 (25%), Positives = 68/205 (33%), Gaps = 34/205 (16%)

Query: 836  RSKAKRSRHHQNPRAEAPCYVSHPSPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRG-- 893
            R KAK     + P A AP  ++   P PP +P P PP T        P  L V    G  
Sbjct: 5    RDKAKAGAAARTPAARAPGLLT---PRPPGSPRPPPPVT--------PAALRVLGAAGAV 53

Query: 894  GPQPLPPAPTSVPPAAFPAPLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHS 953
            G +PL      +  A  P     P           PT S+    + + PA  PP      
Sbjct: 54   GRKPLAERAGGIGGATIPES--APRAG--------PTRSAGT--SSRNPASRPPASGRGE 101

Query: 954  PSPSLPALAPSPPHRPDSPLFNSRCSSPLQLNLLQLEELPRAEGAAV---------AGGP 1004
             +P     +P P   P      +R     Q  L    E   A G A          AG  
Sbjct: 102  RAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGAR 161

Query: 1005 GSSAGPPPPSAEAAEPEARLAEVTE 1029
              ++GP P +   A      A  TE
Sbjct: 162  RDTSGPTPGTPSPAMARRSRAAGTE 186



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 46/162 (28%), Positives = 57/162 (35%), Gaps = 40/162 (24%)

Query: 750 LAPGPAPSPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRGLDS 809
           LAPGP P P+ SP+ +    PD     G + +  S  T +E             LRG DS
Sbjct: 876 LAPGPPPPPSRSPS-STLSGPDL---AGHSSSATS--TPEE-------------LRGYDS 916

Query: 810 SSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEAPCYVSHPSPVPPSTPWP 869
                    E G    P P +    C   A         R  AP      +   P  P P
Sbjct: 917 GP-------EGGAAASPPPDAELAACHPAAW-------SRGPAPPLAFRGA---PGAPLP 959

Query: 870 TPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPTSVPPAAFP 911
            PPAT P  A      L       GP+   PAP ++ P   P
Sbjct: 960 WPPATGPGSA----DGLCTIYETEGPESATPAPGALDPGPSP 997


>gi|71852582 aryl hydrocarbon receptor nuclear translocator-like
           isoform b [Homo sapiens]
          Length = 582

 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 90/409 (22%), Positives = 163/409 (39%), Gaps = 78/409 (19%)

Query: 203 EELEHITSEYTLQNQDTFSVAVSFLTGRIVYISEQAAVLLRCKRDVFRGTRFSELLAPQD 262
           +EL+H+     L+  D F   V    G+I+++SE    +L   ++   G    + L P+D
Sbjct: 102 DELKHLI----LRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDLIGQSLFDYLHPKD 157

Query: 263 VG-----VFYGSTAP-SRLPTWGTGASAGSGLRDFTQE------KSVFCRIRGG------ 304
           +      +    TAP  RL    TG    + +            +S FCR++        
Sbjct: 158 IAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSFFCRMKCNRPSVKV 217

Query: 305 PDRD---------PGPRYQPFRLTPYV-----TKIRVS-----DGAPAQPCCLLIAERIH 345
            D+D             +     T Y+     TK+ +      D       CL+   R+H
Sbjct: 218 EDKDFPSTCSKKKDRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLH 277

Query: 346 SGYEAPRIPPDKRI----FTTRHTPSCLFQDVDERAAPLLGYLPQDLLGAPVLLFLHPED 401
           S      +  + R+    + +RH     F  VD+RA  +L YLPQ+LLG     + H +D
Sbjct: 278 SHVVPQPVNGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTSCYEYFHQDD 337

Query: 402 RPLMLAIHKKILQLAGQPFDHSPIRFCARNGEYVTMDTSWAGFVHPWSRKVAFVLGRHKV 461
              +   H+++LQ   +    +  +F  ++G ++T+ + W  F++PW+++V +++  + V
Sbjct: 338 IGHLAECHRQVLQ-TREKITTNCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTV 396

Query: 462 RTAPLNE--DVFTPPAPSPAPSLDTDI-----------------------------QELS 490
             A + E  D   P   +   S+D+ +                             + ++
Sbjct: 397 VLANVLEGGDPTFPQLTASPHSMDSMLPSGEGGPKRTHPTVPGIPGGTRAGAGKIGRMIA 456

Query: 491 EQIHRLLLQPVHSPSPTGLCGVGAVTSPGP-LHSPGSSSDSNGGDAEGP 538
           E+I  +      SPS  G   +   ++P P   SPG     NGG  + P
Sbjct: 457 EEIMEIHRIRGSSPSSCGSSPLNITSTPPPDASSPGGKKILNGGTPDIP 505


>gi|71852580 aryl hydrocarbon receptor nuclear translocator-like
           isoform a [Homo sapiens]
          Length = 625

 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 90/409 (22%), Positives = 163/409 (39%), Gaps = 78/409 (19%)

Query: 203 EELEHITSEYTLQNQDTFSVAVSFLTGRIVYISEQAAVLLRCKRDVFRGTRFSELLAPQD 262
           +EL+H+     L+  D F   V    G+I+++SE    +L   ++   G    + L P+D
Sbjct: 145 DELKHLI----LRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDLIGQSLFDYLHPKD 200

Query: 263 VG-----VFYGSTAP-SRLPTWGTGASAGSGLRDFTQE------KSVFCRIRGG------ 304
           +      +    TAP  RL    TG    + +            +S FCR++        
Sbjct: 201 IAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSFFCRMKCNRPSVKV 260

Query: 305 PDRD---------PGPRYQPFRLTPYV-----TKIRVS-----DGAPAQPCCLLIAERIH 345
            D+D             +     T Y+     TK+ +      D       CL+   R+H
Sbjct: 261 EDKDFPSTCSKKKDRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLH 320

Query: 346 SGYEAPRIPPDKRI----FTTRHTPSCLFQDVDERAAPLLGYLPQDLLGAPVLLFLHPED 401
           S      +  + R+    + +RH     F  VD+RA  +L YLPQ+LLG     + H +D
Sbjct: 321 SHVVPQPVNGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTSCYEYFHQDD 380

Query: 402 RPLMLAIHKKILQLAGQPFDHSPIRFCARNGEYVTMDTSWAGFVHPWSRKVAFVLGRHKV 461
              +   H+++LQ   +    +  +F  ++G ++T+ + W  F++PW+++V +++  + V
Sbjct: 381 IGHLAECHRQVLQ-TREKITTNCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTV 439

Query: 462 RTAPLNE--DVFTPPAPSPAPSLDTDI-----------------------------QELS 490
             A + E  D   P   +   S+D+ +                             + ++
Sbjct: 440 VLANVLEGGDPTFPQLTASPHSMDSMLPSGEGGPKRTHPTVPGIPGGTRAGAGKIGRMIA 499

Query: 491 EQIHRLLLQPVHSPSPTGLCGVGAVTSPGP-LHSPGSSSDSNGGDAEGP 538
           E+I  +      SPS  G   +   ++P P   SPG     NGG  + P
Sbjct: 500 EEIMEIHRIRGSSPSSCGSSPLNITSTPPPDASSPGGKKILNGGTPDIP 548


>gi|42716311 aryl hydrocarbon receptor nuclear translocator-like
           isoform a [Homo sapiens]
          Length = 625

 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 90/409 (22%), Positives = 163/409 (39%), Gaps = 78/409 (19%)

Query: 203 EELEHITSEYTLQNQDTFSVAVSFLTGRIVYISEQAAVLLRCKRDVFRGTRFSELLAPQD 262
           +EL+H+     L+  D F   V    G+I+++SE    +L   ++   G    + L P+D
Sbjct: 145 DELKHLI----LRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDLIGQSLFDYLHPKD 200

Query: 263 VG-----VFYGSTAP-SRLPTWGTGASAGSGLRDFTQE------KSVFCRIRGG------ 304
           +      +    TAP  RL    TG    + +            +S FCR++        
Sbjct: 201 IAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPSRLCSGARRSFFCRMKCNRPSVKV 260

Query: 305 PDRD---------PGPRYQPFRLTPYV-----TKIRVS-----DGAPAQPCCLLIAERIH 345
            D+D             +     T Y+     TK+ +      D       CL+   R+H
Sbjct: 261 EDKDFPSTCSKKKDRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLH 320

Query: 346 SGYEAPRIPPDKRI----FTTRHTPSCLFQDVDERAAPLLGYLPQDLLGAPVLLFLHPED 401
           S      +  + R+    + +RH     F  VD+RA  +L YLPQ+LLG     + H +D
Sbjct: 321 SHVVPQPVNGEIRVKSMEYVSRHAIDGKFVFVDQRATAILAYLPQELLGTSCYEYFHQDD 380

Query: 402 RPLMLAIHKKILQLAGQPFDHSPIRFCARNGEYVTMDTSWAGFVHPWSRKVAFVLGRHKV 461
              +   H+++LQ   +    +  +F  ++G ++T+ + W  F++PW+++V +++  + V
Sbjct: 381 IGHLAECHRQVLQ-TREKITTNCYKFKIKDGSFITLRSRWFSFMNPWTKEVEYIVSTNTV 439

Query: 462 RTAPLNE--DVFTPPAPSPAPSLDTDI-----------------------------QELS 490
             A + E  D   P   +   S+D+ +                             + ++
Sbjct: 440 VLANVLEGGDPTFPQLTASPHSMDSMLPSGEGGPKRTHPTVPGIPGGTRAGAGKIGRMIA 499

Query: 491 EQIHRLLLQPVHSPSPTGLCGVGAVTSPGP-LHSPGSSSDSNGGDAEGP 538
           E+I  +      SPS  G   +   ++P P   SPG     NGG  + P
Sbjct: 500 EEIMEIHRIRGSSPSSCGSSPLNITSTPPPDASSPGGKKILNGGTPDIP 548


>gi|30795242 aryl hydrocarbon receptor nuclear translocator isoform
           3 [Homo sapiens]
          Length = 774

 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 109/481 (22%), Positives = 178/481 (37%), Gaps = 86/481 (17%)

Query: 198 STYTLEELEHITSEYTLQNQDTFSVAVSFLTGRIVYISEQAAVLLRCKRDVFRGTRFSEL 257
           S  T +EL+H+     L+  D F   VS  TGR+VY+S+    +L   +  + G+   + 
Sbjct: 142 SFLTDQELKHLI----LEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQ 197

Query: 258 LAPQDVGVFYGSTAPSRLPTWG------TGASAGSGLRDFTQ-----EKSVFCRIRGGPD 306
           + P DV       + S     G      TG     G +   +      +S  CR+R G  
Sbjct: 198 VHPDDVDKLREQLSTSENALTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGSS 257

Query: 307 ------------------------RDPGPRYQPFRLTPYVTK-----IRVSDGAP----A 333
                                   +D  P +     T Y+       + + D  P     
Sbjct: 258 SVDPVSVNRLSFVRNRCRNGLGSVKDGEPHFVVVHCTGYIKAWPPAGVSLPDDDPEAGQG 317

Query: 334 QPCCLLIAERIHSGYEAPRIPPDKRI-----FTTRHTPSCLFQDVDERAAPLLGYLPQDL 388
              CL+   R+     +P       +     F +RH    +F  VD R    +GY PQ+L
Sbjct: 318 SKFCLVAIGRLQVT-SSPNCTDMSNVCQPTEFISRHNIEGIFTFVDHRCVATVGYQPQEL 376

Query: 389 LGAPVLLFLHPEDRPLMLAIHKKILQLAGQPFDHSPIRFCARNGEYVTMDTSWAGFVHPW 448
           LG  ++ F HPED+ L+    +++++L GQ       RF ++N E++ M TS   F +P+
Sbjct: 377 LGKNIVEFCHPEDQQLLRDSFQQVVKLKGQVLS-VMFRFRSKNQEWLWMRTSSFTFQNPY 435

Query: 449 SRKVAFVL------GRHKVRTAPLNEDVFTPPAPSPAPSLDTDI--QELSEQIHRLLLQP 500
           S ++ +++              P   +    P   P  +L  ++   +L+ +  +   + 
Sbjct: 436 SDEIEYIICTNTNVKNSSQEPRPTLSNTIQRPQLGPTANLPLEMGSGQLAPRQQQQQTEL 495

Query: 501 VHSPSPTGLCG------VGAVTSPGPLHS-PGSSSDSNGGDAEGPGPPAPVTFQQICKDV 553
              P   GL        V  VT+ GP HS P   SD        P       F +I  ++
Sbjct: 496 DMVPGRDGLASYNHSQVVQPVTTTGPEHSKPLEKSDGLFAQDRDP------RFSEIYHNI 549

Query: 554 HLVKHQG---------QQLFIESRARPQSRPRLPATGTFKAKALPCQSPDPELEAGSAPV 604
           +  + +G         QQLF +    P + PR          A P     P   AG    
Sbjct: 550 NADQSKGISSSTVPATQQLFSQGNTFPPT-PRPAENFRNSGLAPPVTIVQPSASAGQMLA 608

Query: 605 Q 605
           Q
Sbjct: 609 Q 609


>gi|4502231 aryl hydrocarbon receptor nuclear translocator isoform 1
           [Homo sapiens]
          Length = 789

 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 109/481 (22%), Positives = 178/481 (37%), Gaps = 86/481 (17%)

Query: 198 STYTLEELEHITSEYTLQNQDTFSVAVSFLTGRIVYISEQAAVLLRCKRDVFRGTRFSEL 257
           S  T +EL+H+     L+  D F   VS  TGR+VY+S+    +L   +  + G+   + 
Sbjct: 157 SFLTDQELKHLI----LEAADGFLFIVSCETGRVVYVSDSVTPVLNQPQSEWFGSTLYDQ 212

Query: 258 LAPQDVGVFYGSTAPSRLPTWG------TGASAGSGLRDFTQ-----EKSVFCRIRGGPD 306
           + P DV       + S     G      TG     G +   +      +S  CR+R G  
Sbjct: 213 VHPDDVDKLREQLSTSENALTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGSS 272

Query: 307 ------------------------RDPGPRYQPFRLTPYVTK-----IRVSDGAP----A 333
                                   +D  P +     T Y+       + + D  P     
Sbjct: 273 SVDPVSVNRLSFVRNRCRNGLGSVKDGEPHFVVVHCTGYIKAWPPAGVSLPDDDPEAGQG 332

Query: 334 QPCCLLIAERIHSGYEAPRIPPDKRI-----FTTRHTPSCLFQDVDERAAPLLGYLPQDL 388
              CL+   R+     +P       +     F +RH    +F  VD R    +GY PQ+L
Sbjct: 333 SKFCLVAIGRLQVT-SSPNCTDMSNVCQPTEFISRHNIEGIFTFVDHRCVATVGYQPQEL 391

Query: 389 LGAPVLLFLHPEDRPLMLAIHKKILQLAGQPFDHSPIRFCARNGEYVTMDTSWAGFVHPW 448
           LG  ++ F HPED+ L+    +++++L GQ       RF ++N E++ M TS   F +P+
Sbjct: 392 LGKNIVEFCHPEDQQLLRDSFQQVVKLKGQVLS-VMFRFRSKNQEWLWMRTSSFTFQNPY 450

Query: 449 SRKVAFVL------GRHKVRTAPLNEDVFTPPAPSPAPSLDTDI--QELSEQIHRLLLQP 500
           S ++ +++              P   +    P   P  +L  ++   +L+ +  +   + 
Sbjct: 451 SDEIEYIICTNTNVKNSSQEPRPTLSNTIQRPQLGPTANLPLEMGSGQLAPRQQQQQTEL 510

Query: 501 VHSPSPTGLCG------VGAVTSPGPLHS-PGSSSDSNGGDAEGPGPPAPVTFQQICKDV 553
              P   GL        V  VT+ GP HS P   SD        P       F +I  ++
Sbjct: 511 DMVPGRDGLASYNHSQVVQPVTTTGPEHSKPLEKSDGLFAQDRDP------RFSEIYHNI 564

Query: 554 HLVKHQG---------QQLFIESRARPQSRPRLPATGTFKAKALPCQSPDPELEAGSAPV 604
           +  + +G         QQLF +    P + PR          A P     P   AG    
Sbjct: 565 NADQSKGISSSTVPATQQLFSQGNTFPPT-PRPAENFRNSGLAPPVTIVQPSASAGQMLA 623

Query: 605 Q 605
           Q
Sbjct: 624 Q 624


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
          Length = 816

 Score = 74.3 bits (181), Expect = 7e-13
 Identities = 150/578 (25%), Positives = 195/578 (33%), Gaps = 93/578 (16%)

Query: 516  TSPGPLHSPGSSSDSNGGDAEGPGPPAPVTFQQICKDVHLVKHQGQQLFIESRARPQSRP 575
            TSPGP+ SPG +S        G   P P+  + +         +G+      R+   +  
Sbjct: 100  TSPGPVSSPGRAS--------GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGA 151

Query: 576  RLPATGTFKAKALPC---QSPDPELEAGSAPVQAPLALV--PEEAERKEASSCSYQQINC 630
            R   +G       P    +S     E G  P  AP A    P E  RK  SS S      
Sbjct: 152  RRDTSGPTPGTPSPAMARRSRAAGTEVG-LPRPAPSARPRPPTEGPRKSVSSASEHSTTE 210

Query: 631  LDSILRYLESCN--LPSTTKRKCASSSSYTTSSASDDDRQRTGPVSVGTKKDP--PS--- 683
                 R   S    L     R  +SS++  +S A      R+GP + GT + P  PS   
Sbjct: 211  PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA------RSGPSARGTPRAPAHPSQPK 264

Query: 684  -----AALSGEGATPRKEPVVG-GTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPP 737
                 A    +   PRK+     G LS   LA  + S     S      T+       P 
Sbjct: 265  PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPS 324

Query: 738  ESDIIMMEDLPGLAPGPAPSPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSR 797
            ++   +            PSP  SP   P P      P  L    L           LS 
Sbjct: 325  QATTSLGSPTLQATHSFLPSPPLSPLATPPPQA----PPALALPPLQAPPSPPASPPLSP 380

Query: 798  FRDLGRLRGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEAPCYVS 857
                        S  AP+AL         +PP                 +P  +AP    
Sbjct: 381  LAT--------PSPQAPNALAVHLLQAPFSPPP----------------SPPVQAPFSPP 416

Query: 858  HPSPVPPSTPWPT--PPATTPFPAVVQPYP--LPVFSPRGGPQPLPPAPTSVPPA--AFP 911
               PV PS   P+  PP+    P  V P P   P  SP   P P  P P + PP   A P
Sbjct: 417  ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 476

Query: 912  APLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLP--ALAPSPPHRP 969
             P   P +A         TP   P  AL +P    P  A  SPS SLP   LA  PP  P
Sbjct: 477  PPQAPPALA---------TP---PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 524

Query: 970  D---SPLFNSRCSSPLQLNLLQLEELPRAEGAAVAGGP----GSSAGPPPPSAEAAEPEA 1022
                +PL     S P    L      P         GP      + GPPPP + +  P +
Sbjct: 525  PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS--PSS 582

Query: 1023 RLAEVTESSNQDALSGSSDLLELLLQEDSRSGTGSAAS 1060
             L+    + +    S ++   E L   DS    G+AAS
Sbjct: 583  TLSGPDLAGHS---SSATSTPEELRGYDSGPEGGAAAS 617



 Score = 71.2 bits (173), Expect = 6e-12
 Identities = 122/440 (27%), Positives = 155/440 (35%), Gaps = 99/440 (22%)

Query: 669  RTGPVSVGTKKDPPSAALSGEGATPRKEPVVG---------GTLSPLALANKAESVVSVT 719
            R GP    T+   P A+  GE A P K    G         GT  P  L  K   +    
Sbjct: 76   RAGP----TRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI---- 127

Query: 720  SQCSFSSTIVHVGDKKPPESDIIMM---EDLPGLAPG-PAPSPAPSPTVA------PDPA 769
               S   T+      + P+   +      D  G  PG P+P+ A     A      P PA
Sbjct: 128  ---SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 184

Query: 770  PDAY-RPV--GLTKAVLSL--HTQKEEQAFLSRFRDLG------RLRGLDSSST-----A 813
            P A  RP   G  K+V S   H+  E      R    G        R L SS+T     A
Sbjct: 185  PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 244

Query: 814  PSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEAP--------CYVSHPSPVPPS 865
             S    RG    PA PS+      +A R      PR +A           ++ PSP  P 
Sbjct: 245  RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPP 304

Query: 866  TP--------WPTPPATTPFPAVVQP-----------YPLPVFSPRGGPQPLPPAPTSVP 906
            +P         P+PPAT P  A                P P  SP   P P  P   ++P
Sbjct: 305  SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP 364

Query: 907  PAAFP---------APLVTPM------VALVLPNYLFPTPSSYPYGA-LQTPAEGPPTPA 950
            P   P         +PL TP       +A+ L    F  P S P  A    PA  P +P+
Sbjct: 365  PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424

Query: 951  SHSPSPSLPALA-------PSPPHRP---DSPLFNSRCSSPLQLNLLQLEELPRAEGAAV 1000
            +  PS + P+LA       PSPP  P    S     +   PL    LQL + P     A+
Sbjct: 425  ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 484

Query: 1001 AGGPGSSAGPPPPSAEAAEP 1020
            A  P  +   PP S     P
Sbjct: 485  ATPPLQALPSPPASFPGQAP 504



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 93/364 (25%), Positives = 116/364 (31%), Gaps = 89/364 (24%)

Query: 748  PGL-APGPAPSPAPSPTVAP------------DPAPDAYRPVGLTKAVLSLHTQKEEQAF 794
            PGL  P P  SP P P V P               P A R  G+  A +     +     
Sbjct: 22   PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81

Query: 795  LSRFRDLGR----------------LRGLDSSSTAPSALGERGCH--------HGPAPPS 830
             SR    GR                  G  S +T P  LG++G           G A  +
Sbjct: 82   TSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEA 141

Query: 831  -RRHHCRSKAKRSRHHQNPRAEAPCY----------VSHPSPVPPSTPWPTPPATTPFPA 879
             +R    + A+R      P   +P            V  P P P +   P PP   P  +
Sbjct: 142  PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR--PRPPTEGPRKS 199

Query: 880  V--------VQPYPLPVFSPRGGPQPLPPA---------PTSVPPAAFPAPLVTP----- 917
            V         +P P     P  G     PA         P S P  + P+   TP     
Sbjct: 200  VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 259

Query: 918  --------MVALVLPNYLFP----TPSSYPYGALQTPAEGPPTPASHSPSPSLPALAPSP 965
                    + AL  P    P     P+  P  +       P  P S S  PSL  L PSP
Sbjct: 260  PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTL-PSP 318

Query: 966  PHRPDSPLFNSRCSSPLQLNLLQLEELPRAEGAA-VAGGPGSSAGPP---PPSAEAAEPE 1021
            P  P S    S  S  LQ     L   P +  A      P + A PP   PPS  A+ P 
Sbjct: 319  PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 378

Query: 1022 ARLA 1025
            + LA
Sbjct: 379  SPLA 382



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 79/295 (26%), Positives = 100/295 (33%), Gaps = 26/295 (8%)

Query: 748  PGLAPGPAP-SPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRG 806
            P   PG AP SP+ S  ++P   P    P  L   +L +         L   R      G
Sbjct: 496  PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR-PPTPG 554

Query: 807  LDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEAP----CYVSHPSPV 862
             D+S + P  L        P PPSR             H +     P     Y S P   
Sbjct: 555  PDTSVSGPR-LTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 613

Query: 863  PPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGP-QPLPPAPTSVPPAAFPAPLV----TP 917
              ++P P        PA     P P  + RG P  PLP  P + P +A     +     P
Sbjct: 614  AAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGP 673

Query: 918  MVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLPALAPSPPHRPDSPLFNSR 977
              A   P  L P PS    G       G     + S SP    L   P          + 
Sbjct: 674  ESATPAPGALDPGPSPGTSGGKAAAGAG---AGASSRSPKQARLGELP--------LGAL 722

Query: 978  CSSPLQLNLLQLEELPRAEGAA--VAGGP-GSSAGPPPPSAEAAEPEARLAEVTE 1029
             +S +Q  L +   L  AEGAA    GGP G+  G     A AA  +A L    E
Sbjct: 723  QASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAE 777



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 64/247 (25%), Positives = 78/247 (31%), Gaps = 59/247 (23%)

Query: 836  RSKAKRSRHHQNPRAEAPCYVSHPSPVPPSTPWPTPPATTPF---PAVVQPYPL------ 886
            R KAK     + P A AP  ++   P  P  P P  PA          V   PL      
Sbjct: 5    RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG 64

Query: 887  ------PVFSPRGGPQPLPPAPTS-----VPPA--AFPAPLVTPMVA--LVLPNYL---- 927
                  P  +PR GP      P S      PPA    P P+ +P  A     P  L    
Sbjct: 65   IGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 124

Query: 928  ----------------FPTPSSYPYGALQT---PAEGPPTPA----SHSPSPSLPALAPS 964
                             P  S+   GA +    P  G P+PA    S +    +    P+
Sbjct: 125  LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 184

Query: 965  PPHRPDSPLFNSRCSSPLQLNLLQLEELPRAEGAAVAGG----PG----SSAGPPPPSAE 1016
            P  RP  P    R S          E  P A     AGG    P     SS+  P  S  
Sbjct: 185  PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 244

Query: 1017 AAEPEAR 1023
             + P AR
Sbjct: 245  RSGPSAR 251


>gi|31745180 aryl hydrocarbon receptor nuclear translocator-like 2
           [Homo sapiens]
          Length = 636

 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 114/529 (21%), Positives = 199/529 (37%), Gaps = 74/529 (13%)

Query: 38  GPSLADDTDANSNGSSGNESNGHESRGASQRSSHSSS---SGNGKDSALLET---TESSK 91
           G  L ++    +   S   S G         SSH +       G DS   ++   TE   
Sbjct: 11  GKVLREENQCIAPVVSSRVSPGTRPTAMGSFSSHMTEFPRKRKGSDSDPSQSGIMTEKVV 70

Query: 92  STNSQSPSPP--SSSIAYSLLSASSEQDNPSTSGCSSEQSARARTQK----ELMTALREL 145
              SQ+P     S+ I  S  S S  +D        + + A ++T+K    ++   + EL
Sbjct: 71  EKLSQNPLTYLLSTRIEISASSGSRVEDGEHQVKMKAFREAHSQTEKRRRDKMNNLIEEL 130

Query: 146 KLRLPPERRGKGRSGTLATLQYALACVKQVQANQEYYQQWSLEEGEPCSMDMSTYTLEEL 205
              +P       +   L  L+ A+  ++ ++     Y   +           S     EL
Sbjct: 131 SAMIPQCNPMARKLDKLTVLRMAVQHLRSLKGLTNSYVGSNYRP--------SFLQDNEL 182

Query: 206 EHITSEYTLQNQDTFSVAVSFLTGRIVYISEQAAVLLRCKRDVFRGTRFSELLAPQDVGV 265
            H+     L+  + F   V    G+I+++S+  + +L   +    G    + L P+DV  
Sbjct: 183 RHLI----LKTAEGFLFVVGCERGKILFVSKSVSKILNYDQASLTGQSLFDFLHPKDVAK 238

Query: 266 F------YGSTAPSRLPTWGTGASAGSGL-----RDFT-QEKSVFCRIRG---------- 303
                  +  +   +L    TG    S L     R ++   +S FCRI+           
Sbjct: 239 VKEQLSSFDISPREKLIDAKTGLQVHSNLHAGRTRVYSGSRRSFFCRIKSCKISVKEEHG 298

Query: 304 ---GPDRDPGPRYQPFRLTPYVT----------KIRVSDGAPAQPCCLLIAERIHSGYEA 350
                 +    ++     T Y+           + R S    +   CL+   R+   Y  
Sbjct: 299 CLPNSKKKEHRKFYTIHCTGYLRSWPPNIVGMEEERNSKKDNSNFTCLVAIGRLQP-YIV 357

Query: 351 PRIPPDKRI----FTTRHTPSCLFQDVDERAAPLLGYLPQDLLGAPVLLFLHPEDRPLML 406
           P+   +  +    F TR   +  F  VD+RA  +LGYLPQ+LLG     + H +D   + 
Sbjct: 358 PQNSGEINVKPTEFITRFAVNGKFVYVDQRATAILGYLPQELLGTSCYEYFHQDDHNNLT 417

Query: 407 AIHKKILQLAGQPFDHSPIRFCARNGEYVTMDTSWAGFVHPWSRKVAFVLGRHKVRTAPL 466
             HK +LQ   +    S  +F A++G +VT+ + W  F +PW++++ +++         +
Sbjct: 418 DKHKAVLQSKEKILTDS-YKFRAKDGSFVTLKSQWFSFTNPWTKELEYIVS--------V 468

Query: 467 NEDVFTPPAPSPAPSLDTDIQELSEQIHRLLLQPVHSPSPTGLCGVGAV 515
           N  V     P  A  L    Q  SE+  R     V   S   + G G++
Sbjct: 469 NTLVLGHSEPGEASFLPCSSQS-SEESSRQSCMSVPGMSTGTVLGAGSI 516


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 122/428 (28%), Positives = 153/428 (35%), Gaps = 85/428 (19%)

Query: 749  GLAPGPAPSPAPSPTV-APDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRGL 807
            G AP P P P PSP   AP P P  + P    + VL L             R+LG   GL
Sbjct: 1371 GGAPQPPPRP-PSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPAR---RELGYRAGL 1426

Query: 808  DSSS----TAPSALGERGCHHGP--AP------------PSRRHHCRSKAKRSRHHQNPR 849
             S       +P A      H  P  AP            P   H   SK  RS   + P 
Sbjct: 1427 GSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPE 1486

Query: 850  AEAPCYV---SHPSPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPTS-- 904
               P +V    +  P  P T    PP+    P V  P      SPR   + +PP+PTS  
Sbjct: 1487 -RLPLHVRFLENCQPRAPVTSGRGPPSEDG-PGVPPP------SPR---RSVPPSPTSPR 1535

Query: 905  ------VPPAAFPAPLVTPMVALVLPNYLF--PTPSSYPYGALQTPAEGPPTPASHSPSP 956
                  +P    P P   P V +    +LF  P P    +       E P TP    P P
Sbjct: 1536 ASEENGLPLLVLPPP--APSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLP 1593

Query: 957  SLPALA-PSPPHRPDS-----PLFNSRCSSPLQLNLLQLEELPRAEGAAVAGGPGSSAGP 1010
              PA A P PP  P +     P  +S  SS   L     E     +GA+ A G     GP
Sbjct: 1594 DTPAPATPLPPVPPPAVAAAPPTLDSTASS---LTSYDSEVATLTQGASAAPGDPHPPGP 1650

Query: 1011 PPPSAEAA---EPEARLAEVTESSNQ--DALSGSSDLLELLLQEDSRSGTGSAASGSLGS 1065
            P P+A A    +P       T+S  +  D+ S S   LE +    + S   +   GS G 
Sbjct: 1651 PAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGG 1710

Query: 1066 GLGSGSG---------------SGSHEGGSTSASITRSSQSSHTSKYFGSIDSSEAEAGA 1110
            G G+G+G                G   GGS++       Q    SK  G        A  
Sbjct: 1711 GGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRG-------RALG 1763

Query: 1111 ARGGAEPG 1118
            A GG  PG
Sbjct: 1764 ASGGLRPG 1771



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 122/574 (21%), Positives = 183/574 (31%), Gaps = 102/574 (17%)

Query: 551  KDVHLVKHQGQQLFIESRARPQSRPRLPATGTFKAKALPCQSPDPELEAGSAPVQAPLAL 610
            K V + +H      +  +A  Q++   P T + ++K++  +  + E E   APV +    
Sbjct: 752  KVVMVTRHPDMDEAVHKKAPQQAKRLPPPTISLRSKSMTSELEEMEYEQQPAPVPS---- 807

Query: 611  VPEEAERKEASSCSYQQ-INCLDSILRYLESCNLPSTTKRKCASSS-------SYTTSSA 662
                    E     YQ  +N LD IL   +     S +      +S        +  + +
Sbjct: 808  -------MEKKRTVYQMALNKLDEILAAAQQTISASESPGPGGLASLGKHRPKGFFATES 860

Query: 663  SDDDRQRTGPVSVGTKKDPPSAALSGEGATPRKEPVVGGTLSPLALANKAESVVSVTSQC 722
            S D   R  P       + PS    G G   R++ +         LA  A          
Sbjct: 861  SFDPHHRAQP-----SYERPSFLPPGPGLMLRQKSIGAAEDDRPYLAPPA---------M 906

Query: 723  SFSSTIVHVGDKKPPESDIIMMEDLPGLAPGPAPSPAPSPTVAPDPAPDAYRPVGLTKAV 782
             FS ++   G +  P        + P   P   P P+ S  + P P    + P       
Sbjct: 907  KFSRSLSVPGSEDIPPPPTTSPPEPPYSTP---PVPSSSGRLTPSPRGGPFNPGSGGPLP 963

Query: 783  LSLHTQKEEQAFLSRFRDLGRLRGLDSSSTAPSALGERG---CHHGPAPPSRRHHCRSKA 839
             S                       D  S   + +G R     H GP PP+  H      
Sbjct: 964  ASSPA------------------SFDGPSPPDTRVGSREKSLYHSGPLPPAHHH-----P 1000

Query: 840  KRSRHHQNPRAEAPCYVSHPSPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLP 899
                HH  P  +   + +HP P PP       P   P    + P P       GGP P P
Sbjct: 1001 PHHHHHHAPPPQPHHHHAHP-PHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTP 1059

Query: 900  PAPT----------------------SVPPAAFPAPLVTPMVA-------LVLPNYLFPT 930
             AP+                       +PP A  A +  P  +       LV    +   
Sbjct: 1060 GAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGE 1119

Query: 931  PSSYPYGALQTPAEGPPTPASHSPSPSLPALA-----PSPPHRPDSPLFNSRCSSPLQLN 985
            P     G    PA  P +PAS  P P++ A +     P P     +P  +S   S  Q +
Sbjct: 1120 PQK---GGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSS-QGS 1175

Query: 986  LLQLEELPRAEGAAVAGGPGSSAGPPPPSAEAAEPEARLAEVTESSNQDALSGSSDLLEL 1045
              + E   + E     GG GSS  P P  +      + +      S    L  +S     
Sbjct: 1176 STEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAA 1235

Query: 1046 LLQEDSRSGTGSAASGSLGSGLGSGSGSGSHEGG 1079
            L+    R G G        S L   + +G  +GG
Sbjct: 1236 LVGAARREG-GWQNEARRRSTLFLSTDAGDEDGG 1268



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 104/417 (24%), Positives = 135/417 (32%), Gaps = 125/417 (29%)

Query: 750  LAPGPA----PSPAPSPTVAPDPAPD-AYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRL 804
            L PGP      +PAP+  + P P P  A  P  L     SL +   E A L++       
Sbjct: 1584 LTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQ------- 1636

Query: 805  RGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEAPCYVSHPSPVPP 864
                 +S AP      G  H P PP+                 P A AP         PP
Sbjct: 1637 ----GASAAP------GDPHPPGPPA-----------------PAAPAPAAPQPGPDPPP 1669

Query: 865  STPWPTPPATT------PFPAVVQPYPLPVFSPRGG----------------PQPLPP-- 900
             T        +      P   +     L   S  GG                P+ L    
Sbjct: 1670 GTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYV 1729

Query: 901  --------APTSVPPAAFPAPLVTPMV----ALVLPNYLFPTPSSYPYGALQTPAE--GP 946
                      +S P   +P  L+TP      AL     L P PS    G L+ P     P
Sbjct: 1730 AYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPS----GGLRDPVTPTSP 1785

Query: 947  PTPASHSPSPSLPAL--APSPPH----------RPDSPLFNSRCSSPLQLNLLQLEELPR 994
                + + +  L AL     PP            P+ P      +S L   LL  EE   
Sbjct: 1786 TVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEE--- 1842

Query: 995  AEGAAVAGGPGSSAGPPPPSAEAAEPEARLAEVTESSNQDALSGSSDLLELLLQEDSRSG 1054
                    GPG    PPP     A+P+A      ++S    LS        L Q    S 
Sbjct: 1843 --------GPGPP--PPPLPGPLAQPQASALATVKASIISELSSK------LQQFGGSSA 1886

Query: 1055 TGSAASGSLGSGLGSGSGSGSHEGGST-----SASITR-----SSQSSHTSKYFGSI 1101
             G A   + G   GSG G  SH GG++     ++S+ R      SQSS  SK   S+
Sbjct: 1887 AGGALPWARG---GSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSL 1940



 Score = 34.7 bits (78), Expect = 0.61
 Identities = 22/72 (30%), Positives = 26/72 (36%)

Query: 11   GGDPRPGESFCPGGVPSPGPPQHRPCPGPSLADDTDANSNGSSGNESNGHESRGASQRSS 70
            G    PG+   PG      P    P PGP     TD+         S+ H     S  S+
Sbjct: 1637 GASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSAST 1696

Query: 71   HSSSSGNGKDSA 82
             SS S  G  SA
Sbjct: 1697 LSSLSAEGGGSA 1708



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 52/223 (23%), Positives = 75/223 (33%), Gaps = 28/223 (12%)

Query: 859  PSPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPTSVPPAAFPAPLVTPM 918
            P+P P S   P PP     P+     P+P    +  P       +S   +    P   P 
Sbjct: 1128 PAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIK-APSTSSSGRSSQGSSTEAEPPTQPE 1186

Query: 919  VALVLPNYLFPTPSSYPYGALQTPAEG-PPTPASHSPSPSLPALAPSPPHRPDSPLFNSR 977
                      PT      G+  +PA    P P S SP P+     P+ P  P +  F S+
Sbjct: 1187 ----------PTGGGGGGGSSPSPAPAMSPVPPSPSPVPT-----PASPSGPATLDFTSQ 1231

Query: 978  CSSPLQLNLLQLE-----ELPRAEGAAVAGGPGSSAGPPPPSAEAAEPEARLAEVTESSN 1032
              + L +   + E     E  R     ++   G   G        A P  RL      S 
Sbjct: 1232 FGAAL-VGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRH--SKSI 1288

Query: 1033 QDALSGSSDLLELLLQEDSRSGTGSAASGSLGSGLGSGSGSGS 1075
             + +  +   L L   E + SG G    G+     G G GS +
Sbjct: 1289 DEGMFSAEPYLRL---ESAGSGAGYGGYGAGSRAYGGGGGSSA 1328



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 29/105 (27%), Positives = 38/105 (36%), Gaps = 22/105 (20%)

Query: 12   GDPRPGESFCPGGVPSPGPPQHRPCPGPSLADDTDANS------------NGSSGNESNG 59
            G+P+ G    P   PSP  P   P P P++A  ++ NS              SSG  S G
Sbjct: 1118 GEPQKGGGLPPA--PSPTSPAS-PQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQG 1174

Query: 60   HESRGASQRSSHSSSSGNGKDSALLETTESSKSTNSQSPSPPSSS 104
              +          +  G G  S       S     + SP PPS S
Sbjct: 1175 SSTEAEPPTQPEPTGGGGGGGS-------SPSPAPAMSPVPPSPS 1212



 Score = 31.2 bits (69), Expect = 6.7
 Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 11/120 (9%)

Query: 655  SSYTTSSASDDDRQRTGPVSVGTKKDPPSAALSGEGATPRKEPVVGGT-LSPLALANKAE 713
            +SY     S   RQR    S  +    P ++L      P   P+  GT +SP A A    
Sbjct: 1909 ASYVPERTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGA 1968

Query: 714  SVVSVTSQCSFSSTIVHVG-DKKPPESDIIMMEDLPGLAPGPAPSPAPSPTVAPDPAPDA 772
            +  S +S  + +  +  V  + +PP         L   AP P+  PA    V+P P P +
Sbjct: 1969 TSPSASSSSTSTRHLQGVEFEMRPP---------LLRRAPSPSLLPASEHKVSPAPRPSS 2019


>gi|68303555 aryl hydrocarbon receptor nuclear translocator 2 [Homo
           sapiens]
          Length = 717

 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 71/310 (22%), Positives = 121/310 (39%), Gaps = 59/310 (19%)

Query: 198 STYTLEELEHITSEYTLQNQDTFSVAVSFLTGRIVYISEQAAVLLRCKRDVFRGTRFSEL 257
           S  T +EL+H+     L+  D F   V+  TGR++Y+S+    +L   +  + G+   E 
Sbjct: 131 SFLTEQELKHLI----LEAADGFLFVVAAETGRVIYVSDSVTPVLNQPQSEWFGSTLYEQ 186

Query: 258 LAPQDVGVFYGSTAPSRLPTWG------TGASAGSGLRDFTQ-----EKSVFCRIRGG-- 304
           + P DV         S     G      TG     G +   +      +S  CR+R G  
Sbjct: 187 VHPDDVEKLREQLCTSENSMTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGNA 246

Query: 305 ----------------------PDRDPGPRYQPFRLTPYVTKI---------RVSDGAPA 333
                                 P ++   +Y     T Y+              +D    
Sbjct: 247 PLDHLPLNRITTMRKRFRNGLGPVKEGEAQYAVVHCTGYIKAWPPAGMTIPEEDADVGQG 306

Query: 334 QPCCLLIAERIH-------SGYEAPRIPPDKRIFTTRHTPSCLFQDVDERAAPLLGYLPQ 386
              CL+   R+               +P +   F +RH    +   VD R   ++GY PQ
Sbjct: 307 SKYCLVAIGRLQVTSSPVCMDMNGMSVPTE---FLSRHNSDGIITFVDPRCISVIGYQPQ 363

Query: 387 DLLGAPVLLFLHPEDRPLMLAIHKKILQLAGQPFDHSPIRFCARNGEYVTMDTSWAGFVH 446
           DLLG  +L F HPED+  +    +++++L GQ       RF  +N E++ + TS   F +
Sbjct: 364 DLLGKDILEFCHPEDQSHLRESFQQVVKLKGQVLS-VMYRFRTKNREWMLIRTSSFTFQN 422

Query: 447 PWSRKVAFVL 456
           P+S ++ +++
Sbjct: 423 PYSDEIEYII 432


>gi|195963410 MEF2 activating motif and SAP domain containing
            transcriptional regulator isoform 1 [Homo sapiens]
          Length = 415

 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 85/286 (29%), Positives = 108/286 (37%), Gaps = 46/286 (16%)

Query: 752  PGPAPSP-APSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRGLDSS 810
            P   PSP  P P   P P+P  ++        L L T K E+  +S  R   RLRGL  S
Sbjct: 141  PRMKPSPLTPCPPGVPSPSPPPHK--------LELQTLKLEELTVSELRQQLRLRGLPVS 192

Query: 811  STAPSALGERGCHHGPAPPSRRHHCR---SKAKRSRHHQNPRAEA---------PCYVSH 858
             T  S L ER    G APP  R   R   S A        P+A A         P   SH
Sbjct: 193  GTK-SMLLER--MRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASH 249

Query: 859  PSPVPPSTPWP-TPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPTSVPPAAFPAPLVTP 917
              P+P +   P T PA TP PA   P   P  +P  GP             +    L   
Sbjct: 250  RPPLPRAADTPGTAPAPTPTPA---PAAAPALTPSSGP------------GSAALTLEEE 294

Query: 918  MVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLPALAPSPPHRPDSPLFNSR 977
            +   +    L P          Q   + P  P       S   L+PSP     S +F+S 
Sbjct: 295  LQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSS 354

Query: 978  CSSPLQLNLLQ----LEELPRAEGAAVAGGPGSSAGPPPPSAEAAE 1019
              SP   +        + L   E  A++GGP   +GPPPPS  +A+
Sbjct: 355  LPSPTNSSSPSPRDPTDSLDWLE--ALSGGPPLGSGPPPPSIFSAD 398



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 47/168 (27%), Positives = 60/168 (35%), Gaps = 21/168 (12%)

Query: 747 LPGLAPGPAPSPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRG 806
           LP  A  P  +PAP+PT AP  AP      G   A L+L  + +E     R   L   RG
Sbjct: 253 LPRAADTPGTAPAPTPTPAPAAAPALTPSSGPGSAALTLEEELQEAI---RRAQLLPNRG 309

Query: 807 LDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEAPCYVSHPSPVPPST 866
           +D        L ++     P PP       S    S    +    +    S PSP   S+
Sbjct: 310 ID------DILEDQVEPDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSS 363

Query: 867 PWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPTSVPPAAFPAPL 914
           P P  P  +          L       G  PL   P   PP+ F A L
Sbjct: 364 PSPRDPTDS----------LDWLEALSGGPPLGSGPP--PPSIFSADL 399



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 41/142 (28%), Positives = 47/142 (33%), Gaps = 18/142 (12%)

Query: 891  PRGGPQPLPPAPTSVPPAAFPAPLVTPMVALVLPNY----------LFPTPSSYPYGALQ 940
            PR  P PL P P  VP  + P P    +  L L             L   P S     L 
Sbjct: 141  PRMKPSPLTPCPPGVPSPS-PPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLL 199

Query: 941  TPAEG--PPTPASHSPSPSLPALAPSPPHRPDSPLFNSRCSSPLQLNLLQLEELPRAEGA 998
                G  PP           PA AP P  +P +     R  S           LPRA   
Sbjct: 200  ERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRA--- 256

Query: 999  AVAGGPGSSAGPPPPSAEAAEP 1020
              A  PG++  P P  A AA P
Sbjct: 257  --ADTPGTAPAPTPTPAPAAAP 276


>gi|32698970 MEF2 activating motif and SAP domain containing
            transcriptional regulator isoform 2 [Homo sapiens]
          Length = 312

 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 85/286 (29%), Positives = 108/286 (37%), Gaps = 46/286 (16%)

Query: 752  PGPAPSP-APSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRGLDSS 810
            P   PSP  P P   P P+P  ++        L L T K E+  +S  R   RLRGL  S
Sbjct: 38   PRMKPSPLTPCPPGVPSPSPPPHK--------LELQTLKLEELTVSELRQQLRLRGLPVS 89

Query: 811  STAPSALGERGCHHGPAPPSRRHHCR---SKAKRSRHHQNPRAEA---------PCYVSH 858
             T  S L ER    G APP  R   R   S A        P+A A         P   SH
Sbjct: 90   GTK-SMLLER--MRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASH 146

Query: 859  PSPVPPSTPWP-TPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPTSVPPAAFPAPLVTP 917
              P+P +   P T PA TP PA   P   P  +P  GP             +    L   
Sbjct: 147  RPPLPRAADTPGTAPAPTPTPA---PAAAPALTPSSGP------------GSAALTLEEE 191

Query: 918  MVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLPALAPSPPHRPDSPLFNSR 977
            +   +    L P          Q   + P  P       S   L+PSP     S +F+S 
Sbjct: 192  LQEAIRRAQLLPNRGIDDILEDQVEPDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSS 251

Query: 978  CSSPLQLNLLQ----LEELPRAEGAAVAGGPGSSAGPPPPSAEAAE 1019
              SP   +        + L   E  A++GGP   +GPPPPS  +A+
Sbjct: 252  LPSPTNSSSPSPRDPTDSLDWLE--ALSGGPPLGSGPPPPSIFSAD 295



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 47/168 (27%), Positives = 60/168 (35%), Gaps = 21/168 (12%)

Query: 747 LPGLAPGPAPSPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRG 806
           LP  A  P  +PAP+PT AP  AP      G   A L+L  + +E     R   L   RG
Sbjct: 150 LPRAADTPGTAPAPTPTPAPAAAPALTPSSGPGSAALTLEEELQEAI---RRAQLLPNRG 206

Query: 807 LDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEAPCYVSHPSPVPPST 866
           +D        L ++     P PP       S    S    +    +    S PSP   S+
Sbjct: 207 ID------DILEDQVEPDDPLPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSS 260

Query: 867 PWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPTSVPPAAFPAPL 914
           P P  P  +          L       G  PL   P   PP+ F A L
Sbjct: 261 PSPRDPTDS----------LDWLEALSGGPPLGSGPP--PPSIFSADL 296



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 41/142 (28%), Positives = 47/142 (33%), Gaps = 18/142 (12%)

Query: 891  PRGGPQPLPPAPTSVPPAAFPAPLVTPMVALVLPNY----------LFPTPSSYPYGALQ 940
            PR  P PL P P  VP  + P P    +  L L             L   P S     L 
Sbjct: 38   PRMKPSPLTPCPPGVPSPS-PPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLL 96

Query: 941  TPAEG--PPTPASHSPSPSLPALAPSPPHRPDSPLFNSRCSSPLQLNLLQLEELPRAEGA 998
                G  PP           PA AP P  +P +     R  S           LPRA   
Sbjct: 97   ERMRGGAPPRERPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSAASHRPPLPRA--- 153

Query: 999  AVAGGPGSSAGPPPPSAEAAEP 1020
              A  PG++  P P  A AA P
Sbjct: 154  --ADTPGTAPAPTPTPAPAAAP 173


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 123/506 (24%), Positives = 180/506 (35%), Gaps = 91/506 (17%)

Query: 568  RARPQSRPRLPATGTFKAKALPCQSPDPEL-EAGSAPVQA------PLALVPEEAERKEA 620
            R+  ++ P   +T +  +KA   +    ++ E  S+P+++       +A   EEA+R  +
Sbjct: 53   RSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSS 112

Query: 621  SSCSYQQINCLDSILRYLESCNLPSTTKRKCASSSSYTTSSASD-----DDRQRTGPVSV 675
                 Q+I+            N PS  + + + S S     +SD      D + T P S+
Sbjct: 113  KKTKTQEIS----------RPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSP-SI 161

Query: 676  GTKKD----------------PPSAALSGEGATPRKEPVVGGTLSPLALANKAESVVSVT 719
             + +D                 P A  +  G TP       GT   L       S  +V 
Sbjct: 162  PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGT-PQLPTPGPTPSATAVP 220

Query: 720  SQCSFSSTIVHVGDKKP----PESDIIMMEDLPGLAPGPAPSPAPSPTVAPDP-----AP 770
             Q S +++      + P    P + I   +  P L P   PSP P P  +P P       
Sbjct: 221  PQGSPTASQAPNQPQAPTAPVPHTHI---QQAPALHPQRPPSPHPPPHPSPHPPLQPLTG 277

Query: 771  DAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRGLDSSSTAPSALGERGCHHGPAPPS 830
             A +P   + A   LH Q        +   L +  G       P    +     G +P +
Sbjct: 278  SAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAA 337

Query: 831  RRHHCRSKAKRSR---HHQNPRAEAPCYVSHPSPVPPSTPWPTPPATTPFPAVVQPYPLP 887
               H   +   S+     Q P  E P       P P + P   PP TTP P +  P    
Sbjct: 338  AYPHTSLQLPASQSALQSQQPPREQPL-----PPAPLAMPHIKPPPTTPIPQLPAPQAHK 392

Query: 888  VFSPRGGPQP------LPPAP---------TSVPPAAFPAPLVTPMVALVLPNYLFPTPS 932
                  GP P      LPP P         T  PP+A P PL      L+  +   P+  
Sbjct: 393  HPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPL-----QLMPQSQPLPSSP 447

Query: 933  SYPYGALQTPAEGPPTPASHSPSPSLPALAPSPPHRPDSPLFNSRCSSPLQLNLLQLEEL 992
            + P G  Q+    PP PASH P+  L  +AP PP       F      P+          
Sbjct: 448  AQPPGLTQS-QNLPPPPASHPPT-GLHQVAPQPPFAQHP--FVPGGPPPITPPTCPSTST 503

Query: 993  PRAEGAAVAGGPGSSAGPPPPSAEAA 1018
            P A       GPG+SA PP   A A+
Sbjct: 504  PPA-------GPGTSAQPPCSGAAAS 522



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 62/247 (25%), Positives = 84/247 (34%), Gaps = 41/247 (16%)

Query: 808  DSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSR-HHQNPRAEAPCYVSH-PSPVPPS 865
            D+ ST+PS          P+P        S A++     Q P  +AP  V+  PS  PP 
Sbjct: 153  DNRSTSPSI---------PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPG 203

Query: 866  TPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPT-------------SVPPAAFPA 912
            TP    P  TP    V P   P  S        P AP                PP+  P 
Sbjct: 204  TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP 263

Query: 913  PLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPAS-------HSPSPSLPALAPSP 965
            P  +P   L         PS+  +       +GPP P S         P P  P   P  
Sbjct: 264  PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQ 323

Query: 966  PHRPDSPLFNSRCSS--------PLQLNLLQLEELPRAEGAAVAGGPGSSAGPPP--PSA 1015
              +  +PL  S  ++        P   + LQ ++ PR +    A        PPP  P  
Sbjct: 324  ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIP 383

Query: 1016 EAAEPEA 1022
            +   P+A
Sbjct: 384  QLPAPQA 390



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 48/177 (27%), Positives = 61/177 (34%), Gaps = 35/177 (19%)

Query: 826 PAPPSRRHHCRSKAKRSRHHQNPRAEAPCYV---SHPSPVPPSTP--------WPTPPAT 874
           P PP+     +  +  S HH       P  +   S P P  P+ P         P PPA+
Sbjct: 410 PPPPA----LKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS 465

Query: 875 TPFPAVVQPYPLPVFSPR----GGPQPLPPAP---TSVPPAAFPAPLVTPMVALVLPNYL 927
            P   + Q  P P F+      GGP P+ P     TS PPA        P          
Sbjct: 466 HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGS 525

Query: 928 FPTPSSYPYGALQT----------PAEGPPTPASHSPSPSLPALAPSPPHRPDSPLF 974
               SS P   +Q           P   PP P S SP P+   +  +P H   S  F
Sbjct: 526 IAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPT---VVDTPSHASQSARF 579



 Score = 33.1 bits (74), Expect = 1.8
 Identities = 75/321 (23%), Positives = 108/321 (33%), Gaps = 36/321 (11%)

Query: 473 PPAPSPAPSLDTDIQELSEQIHRLLLQP-VHSPSPTGLCGVGA---VTSPGPLHSPGSSS 528
           PP PSP P L        +       QP +H   P G   + A   +  PGP    G   
Sbjct: 263 PPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPP 322

Query: 529 DSNGGDAE-GPGPPA--PVTFQQICKDVHLVKHQGQQLFIESRARPQSRPRLPATGTFKA 585
            ++ G A  G  P A  P T  Q+            Q  ++S+  P+ +P  PA      
Sbjct: 323 QASQGQAPLGTSPAAAYPHTSLQL---------PASQSALQSQQPPREQPLPPAPLAMPH 373

Query: 586 KALPCQSPDPELEA-----------GSAPVQAPLALVPEEAERKEASSCSYQQINCLDSI 634
              P  +P P+L A           G +P      L P  A +  +S  ++   +     
Sbjct: 374 IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPP 433

Query: 635 LRYL-ESCNLPSTTKRKCASSSSYTTSSASDDDRQRTGPVSVGTKKDPPSAALSGEGATP 693
           L+ + +S  LPS+  +    + S             TG   V  +           G  P
Sbjct: 434 LQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS-HPPTGLHQVAPQPPFAQHPFVPGGPPP 492

Query: 694 RKEPVVGGTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPESDIIMMEDL-----P 748
              P    T +P A      S     S  + S   +  G   P  +  I  E L     P
Sbjct: 493 ITPPTCPSTSTPPA--GPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEP 550

Query: 749 GLAPGPAPSPAPSPTVAPDPA 769
              P P  SP+P PTV   P+
Sbjct: 551 ESPPPPPRSPSPEPTVVDTPS 571


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 123/506 (24%), Positives = 180/506 (35%), Gaps = 91/506 (17%)

Query: 568  RARPQSRPRLPATGTFKAKALPCQSPDPEL-EAGSAPVQA------PLALVPEEAERKEA 620
            R+  ++ P   +T +  +KA   +    ++ E  S+P+++       +A   EEA+R  +
Sbjct: 607  RSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSS 666

Query: 621  SSCSYQQINCLDSILRYLESCNLPSTTKRKCASSSSYTTSSASD-----DDRQRTGPVSV 675
                 Q+I+            N PS  + + + S S     +SD      D + T P S+
Sbjct: 667  KKTKTQEIS----------RPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSP-SI 715

Query: 676  GTKKD----------------PPSAALSGEGATPRKEPVVGGTLSPLALANKAESVVSVT 719
             + +D                 P A  +  G TP       GT   L       S  +V 
Sbjct: 716  PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGT-PQLPTPGPTPSATAVP 774

Query: 720  SQCSFSSTIVHVGDKKP----PESDIIMMEDLPGLAPGPAPSPAPSPTVAPDP-----AP 770
             Q S +++      + P    P + I   +  P L P   PSP P P  +P P       
Sbjct: 775  PQGSPTASQAPNQPQAPTAPVPHTHI---QQAPALHPQRPPSPHPPPHPSPHPPLQPLTG 831

Query: 771  DAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRGLDSSSTAPSALGERGCHHGPAPPS 830
             A +P   + A   LH Q        +   L +  G       P    +     G +P +
Sbjct: 832  SAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAA 891

Query: 831  RRHHCRSKAKRSR---HHQNPRAEAPCYVSHPSPVPPSTPWPTPPATTPFPAVVQPYPLP 887
               H   +   S+     Q P  E P       P P + P   PP TTP P +  P    
Sbjct: 892  AYPHTSLQLPASQSALQSQQPPREQPL-----PPAPLAMPHIKPPPTTPIPQLPAPQAHK 946

Query: 888  VFSPRGGPQP------LPPAP---------TSVPPAAFPAPLVTPMVALVLPNYLFPTPS 932
                  GP P      LPP P         T  PP+A P PL      L+  +   P+  
Sbjct: 947  HPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPL-----QLMPQSQPLPSSP 1001

Query: 933  SYPYGALQTPAEGPPTPASHSPSPSLPALAPSPPHRPDSPLFNSRCSSPLQLNLLQLEEL 992
            + P G  Q+    PP PASH P+  L  +AP PP       F      P+          
Sbjct: 1002 AQPPGLTQS-QNLPPPPASHPPT-GLHQVAPQPPFAQHP--FVPGGPPPITPPTCPSTST 1057

Query: 993  PRAEGAAVAGGPGSSAGPPPPSAEAA 1018
            P A       GPG+SA PP   A A+
Sbjct: 1058 PPA-------GPGTSAQPPCSGAAAS 1076



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 62/247 (25%), Positives = 84/247 (34%), Gaps = 41/247 (16%)

Query: 808  DSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSR-HHQNPRAEAPCYVSH-PSPVPPS 865
            D+ ST+PS          P+P        S A++     Q P  +AP  V+  PS  PP 
Sbjct: 707  DNRSTSPSI---------PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPG 757

Query: 866  TPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPT-------------SVPPAAFPA 912
            TP    P  TP    V P   P  S        P AP                PP+  P 
Sbjct: 758  TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP 817

Query: 913  PLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPAS-------HSPSPSLPALAPSP 965
            P  +P   L         PS+  +       +GPP P S         P P  P   P  
Sbjct: 818  PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQ 877

Query: 966  PHRPDSPLFNSRCSS--------PLQLNLLQLEELPRAEGAAVAGGPGSSAGPPP--PSA 1015
              +  +PL  S  ++        P   + LQ ++ PR +    A        PPP  P  
Sbjct: 878  ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIP 937

Query: 1016 EAAEPEA 1022
            +   P+A
Sbjct: 938  QLPAPQA 944



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 48/177 (27%), Positives = 61/177 (34%), Gaps = 35/177 (19%)

Query: 826  PAPPSRRHHCRSKAKRSRHHQNPRAEAPCYV---SHPSPVPPSTP--------WPTPPAT 874
            P PP+     +  +  S HH       P  +   S P P  P+ P         P PPA+
Sbjct: 964  PPPPA----LKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS 1019

Query: 875  TPFPAVVQPYPLPVFSPR----GGPQPLPPAP---TSVPPAAFPAPLVTPMVALVLPNYL 927
             P   + Q  P P F+      GGP P+ P     TS PPA        P          
Sbjct: 1020 HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGS 1079

Query: 928  FPTPSSYPYGALQT----------PAEGPPTPASHSPSPSLPALAPSPPHRPDSPLF 974
                SS P   +Q           P   PP P S SP P+   +  +P H   S  F
Sbjct: 1080 IAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPT---VVDTPSHASQSARF 1133



 Score = 33.1 bits (74), Expect = 1.8
 Identities = 75/321 (23%), Positives = 108/321 (33%), Gaps = 36/321 (11%)

Query: 473  PPAPSPAPSLDTDIQELSEQIHRLLLQP-VHSPSPTGLCGVGA---VTSPGPLHSPGSSS 528
            PP PSP P L        +       QP +H   P G   + A   +  PGP    G   
Sbjct: 817  PPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPP 876

Query: 529  DSNGGDAE-GPGPPA--PVTFQQICKDVHLVKHQGQQLFIESRARPQSRPRLPATGTFKA 585
             ++ G A  G  P A  P T  Q+            Q  ++S+  P+ +P  PA      
Sbjct: 877  QASQGQAPLGTSPAAAYPHTSLQL---------PASQSALQSQQPPREQPLPPAPLAMPH 927

Query: 586  KALPCQSPDPELEA-----------GSAPVQAPLALVPEEAERKEASSCSYQQINCLDSI 634
               P  +P P+L A           G +P      L P  A +  +S  ++   +     
Sbjct: 928  IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPP 987

Query: 635  LRYL-ESCNLPSTTKRKCASSSSYTTSSASDDDRQRTGPVSVGTKKDPPSAALSGEGATP 693
            L+ + +S  LPS+  +    + S             TG   V  +           G  P
Sbjct: 988  LQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS-HPPTGLHQVAPQPPFAQHPFVPGGPPP 1046

Query: 694  RKEPVVGGTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPESDIIMMEDL-----P 748
               P    T +P A      S     S  + S   +  G   P  +  I  E L     P
Sbjct: 1047 ITPPTCPSTSTPPA--GPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEP 1104

Query: 749  GLAPGPAPSPAPSPTVAPDPA 769
               P P  SP+P PTV   P+
Sbjct: 1105 ESPPPPPRSPSPEPTVVDTPS 1125


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 123/506 (24%), Positives = 180/506 (35%), Gaps = 91/506 (17%)

Query: 568  RARPQSRPRLPATGTFKAKALPCQSPDPEL-EAGSAPVQA------PLALVPEEAERKEA 620
            R+  ++ P   +T +  +KA   +    ++ E  S+P+++       +A   EEA+R  +
Sbjct: 607  RSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSS 666

Query: 621  SSCSYQQINCLDSILRYLESCNLPSTTKRKCASSSSYTTSSASD-----DDRQRTGPVSV 675
                 Q+I+            N PS  + + + S S     +SD      D + T P S+
Sbjct: 667  KKTKTQEIS----------RPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSP-SI 715

Query: 676  GTKKD----------------PPSAALSGEGATPRKEPVVGGTLSPLALANKAESVVSVT 719
             + +D                 P A  +  G TP       GT   L       S  +V 
Sbjct: 716  PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGT-PQLPTPGPTPSATAVP 774

Query: 720  SQCSFSSTIVHVGDKKP----PESDIIMMEDLPGLAPGPAPSPAPSPTVAPDP-----AP 770
             Q S +++      + P    P + I   +  P L P   PSP P P  +P P       
Sbjct: 775  PQGSPTASQAPNQPQAPTAPVPHTHI---QQAPALHPQRPPSPHPPPHPSPHPPLQPLTG 831

Query: 771  DAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRGLDSSSTAPSALGERGCHHGPAPPS 830
             A +P   + A   LH Q        +   L +  G       P    +     G +P +
Sbjct: 832  SAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAA 891

Query: 831  RRHHCRSKAKRSR---HHQNPRAEAPCYVSHPSPVPPSTPWPTPPATTPFPAVVQPYPLP 887
               H   +   S+     Q P  E P       P P + P   PP TTP P +  P    
Sbjct: 892  AYPHTSLQLPASQSALQSQQPPREQPL-----PPAPLAMPHIKPPPTTPIPQLPAPQAHK 946

Query: 888  VFSPRGGPQP------LPPAP---------TSVPPAAFPAPLVTPMVALVLPNYLFPTPS 932
                  GP P      LPP P         T  PP+A P PL      L+  +   P+  
Sbjct: 947  HPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPL-----QLMPQSQPLPSSP 1001

Query: 933  SYPYGALQTPAEGPPTPASHSPSPSLPALAPSPPHRPDSPLFNSRCSSPLQLNLLQLEEL 992
            + P G  Q+    PP PASH P+  L  +AP PP       F      P+          
Sbjct: 1002 AQPPGLTQS-QNLPPPPASHPPT-GLHQVAPQPPFAQHP--FVPGGPPPITPPTCPSTST 1057

Query: 993  PRAEGAAVAGGPGSSAGPPPPSAEAA 1018
            P A       GPG+SA PP   A A+
Sbjct: 1058 PPA-------GPGTSAQPPCSGAAAS 1076



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 62/247 (25%), Positives = 84/247 (34%), Gaps = 41/247 (16%)

Query: 808  DSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSR-HHQNPRAEAPCYVSH-PSPVPPS 865
            D+ ST+PS          P+P        S A++     Q P  +AP  V+  PS  PP 
Sbjct: 707  DNRSTSPSI---------PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPG 757

Query: 866  TPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPT-------------SVPPAAFPA 912
            TP    P  TP    V P   P  S        P AP                PP+  P 
Sbjct: 758  TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP 817

Query: 913  PLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPAS-------HSPSPSLPALAPSP 965
            P  +P   L         PS+  +       +GPP P S         P P  P   P  
Sbjct: 818  PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQ 877

Query: 966  PHRPDSPLFNSRCSS--------PLQLNLLQLEELPRAEGAAVAGGPGSSAGPPP--PSA 1015
              +  +PL  S  ++        P   + LQ ++ PR +    A        PPP  P  
Sbjct: 878  ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIP 937

Query: 1016 EAAEPEA 1022
            +   P+A
Sbjct: 938  QLPAPQA 944



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 48/177 (27%), Positives = 61/177 (34%), Gaps = 35/177 (19%)

Query: 826  PAPPSRRHHCRSKAKRSRHHQNPRAEAPCYV---SHPSPVPPSTP--------WPTPPAT 874
            P PP+     +  +  S HH       P  +   S P P  P+ P         P PPA+
Sbjct: 964  PPPPA----LKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS 1019

Query: 875  TPFPAVVQPYPLPVFSPR----GGPQPLPPAP---TSVPPAAFPAPLVTPMVALVLPNYL 927
             P   + Q  P P F+      GGP P+ P     TS PPA        P          
Sbjct: 1020 HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGS 1079

Query: 928  FPTPSSYPYGALQT----------PAEGPPTPASHSPSPSLPALAPSPPHRPDSPLF 974
                SS P   +Q           P   PP P S SP P+   +  +P H   S  F
Sbjct: 1080 IAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPT---VVDTPSHASQSARF 1133



 Score = 33.1 bits (74), Expect = 1.8
 Identities = 75/321 (23%), Positives = 108/321 (33%), Gaps = 36/321 (11%)

Query: 473  PPAPSPAPSLDTDIQELSEQIHRLLLQP-VHSPSPTGLCGVGA---VTSPGPLHSPGSSS 528
            PP PSP P L        +       QP +H   P G   + A   +  PGP    G   
Sbjct: 817  PPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPP 876

Query: 529  DSNGGDAE-GPGPPA--PVTFQQICKDVHLVKHQGQQLFIESRARPQSRPRLPATGTFKA 585
             ++ G A  G  P A  P T  Q+            Q  ++S+  P+ +P  PA      
Sbjct: 877  QASQGQAPLGTSPAAAYPHTSLQL---------PASQSALQSQQPPREQPLPPAPLAMPH 927

Query: 586  KALPCQSPDPELEA-----------GSAPVQAPLALVPEEAERKEASSCSYQQINCLDSI 634
               P  +P P+L A           G +P      L P  A +  +S  ++   +     
Sbjct: 928  IKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPP 987

Query: 635  LRYL-ESCNLPSTTKRKCASSSSYTTSSASDDDRQRTGPVSVGTKKDPPSAALSGEGATP 693
            L+ + +S  LPS+  +    + S             TG   V  +           G  P
Sbjct: 988  LQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS-HPPTGLHQVAPQPPFAQHPFVPGGPPP 1046

Query: 694  RKEPVVGGTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPESDIIMMEDL-----P 748
               P    T +P A      S     S  + S   +  G   P  +  I  E L     P
Sbjct: 1047 ITPPTCPSTSTPPA--GPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEP 1104

Query: 749  GLAPGPAPSPAPSPTVAPDPA 769
               P P  SP+P PTV   P+
Sbjct: 1105 ESPPPPPRSPSPEPTVVDTPS 1125


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
            sapiens]
          Length = 483

 Score = 67.4 bits (163), Expect = 8e-11
 Identities = 79/306 (25%), Positives = 110/306 (35%), Gaps = 45/306 (14%)

Query: 747  LPGLAPGPAPSPAPSPTV-APDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLR 805
            +P   P P P P P P + AP P P +  PV    + L     K   A L+  +   RLR
Sbjct: 1    MPVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLR 60

Query: 806  -----------GLDSS---------------STAPSALGERGCHHGPA--PPSRRHHCRS 837
                        ++SS               ++ P  LG+      P   P  +R     
Sbjct: 61   KVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGG 120

Query: 838  KAKRSRHHQNPRAEAPCYVSHPSPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQP 897
            K  +    + P    P        +PP++P     +     A   P P P       P P
Sbjct: 121  KTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAP-PRPNVPAPPPPTP 179

Query: 898  LPPAPTSVPPAAFPAPLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPS 957
             PP P   PP    +P+ TP+V+          P     G L  P   PP P +  P P 
Sbjct: 180  PPPPPPLPPPLPSSSPIKTPLVS---------PPGPLTKGNL--PVVAPPVPCAPPPPP- 227

Query: 958  LPALAPSPPHRPDSPLFNSRCSSPLQLNLLQLEEL-PRAEGAAVAGGPGSSAGPPPPSAE 1016
             P   P+PP  P + + + +   P QL  L L  + P        G PG  A P  P+ +
Sbjct: 228  -PPPPPTPPPLPPASVLSDKAVKP-QLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQD 285

Query: 1017 AAEPEA 1022
            A EP A
Sbjct: 286  AQEPPA 291


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 104/400 (26%), Positives = 138/400 (34%), Gaps = 86/400 (21%)

Query: 672  PVSVGTKKDPPSAALSGEGATPRKEPVVGGTLSPLALANKAESVVSVTSQC--SFSSTIV 729
            PV+ G    P  A     G  PR  P  G   SP      A  V  + S     FS   +
Sbjct: 814  PVAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPEL 873

Query: 730  HVGDKKPPESDIIMMEDLPG-LAPGPAPSPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQ 788
             +  +    +   +   +P   AP P P+PAP P   P P P    P   T    +    
Sbjct: 874  AMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPL-PTPYTYPAGAKQPI 932

Query: 789  KEEQAFLSRFRDLGRLRGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNP 848
              +  F S         G+ +   AP          GP P   + H +    ++   Q P
Sbjct: 933  PAQHHFSS---------GIPAGFPAPRI--------GPQP---QPHPQPHPSQAFGPQPP 972

Query: 849  RAEAPCYVSHPSPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPTSVPPA 908
            +   P  + HP   PP  P   PP  +P+P   QP  L         QP PP  T +   
Sbjct: 973  QQPLP--LQHPHLFPPQAPGLLPP-QSPYPYAPQPGVL--------GQPPPPLHTQL--- 1018

Query: 909  AFPAPLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLPALAPSPPHR 968
             +P P   P+ A                GAL  P+ GPP P    P P L A  P+P  R
Sbjct: 1019 -YPGPAQDPLPA--------------HSGALPFPSPGPPQP----PHPPL-AYGPAPSTR 1058

Query: 969  PDSPLFNSRCSSPLQLNLLQLEELPRAEGAAV-------AGGPGSSAGPPPPSAEAAEPE 1021
            P  P      ++PL +        P + G +        +  P    GP PP   AAEP 
Sbjct: 1059 PMGPQ-----AAPLTI------RGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAEPP 1107

Query: 1022 ARLAEVTESSNQDALSGSSDLLELLLQEDSRSGTGSAASG 1061
              L     ++  D LS S         E    GT S   G
Sbjct: 1108 PCLRRGAAAA--DLLSSS--------PESQHGGTQSPGGG 1137



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 12/62 (19%)

Query: 848  PRAEAPCYVSHPSPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPTSVPP 907
            P    P  +   +P+P S+P   PP ++P P   QP   P         P+P AP+S PP
Sbjct: 1526 PPGLPPASLPESTPIPSSSP---PPLSSPLPEAPQPKEEP---------PVPEAPSSGPP 1573

Query: 908  AA 909
            ++
Sbjct: 1574 SS 1575



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 25/73 (34%), Positives = 29/73 (39%), Gaps = 11/73 (15%)

Query: 897  PLPPAPTSVPPAAFPAPLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPP---TPASHS 953
            P P  P  +PPA+ P     P  +        P P S P      P E PP    P+S  
Sbjct: 1521 PGPAEPPGLPPASLPESTPIPSSS--------PPPLSSPLPEAPQPKEEPPVPEAPSSGP 1572

Query: 954  PSPSLPALAPSPP 966
            PS SL  LA   P
Sbjct: 1573 PSSSLELLASLTP 1585



 Score = 31.6 bits (70), Expect = 5.1
 Identities = 34/110 (30%), Positives = 41/110 (37%), Gaps = 26/110 (23%)

Query: 935  PYGALQTPAEGPPTPASHS--PSPSLPALAPSPPHRPDSPLFNSRCSSPLQLNLLQLEEL 992
            P G L++P    P PA     P  SLP   P P   P  PL     SSPL          
Sbjct: 1509 PPGGLESPVASLPGPAEPPGLPPASLPESTPIPSSSPP-PL-----SSPL---------- 1552

Query: 993  PRAEGAAVAGGPGSSAGPPPPSAEAAEPEARLAEVTESSNQDALSGSSDL 1042
            P A        P     PP P A ++ P +   E+  S   +A S  S L
Sbjct: 1553 PEA--------PQPKEEPPVPEAPSSGPPSSSLELLASLTPEAFSLDSSL 1594


>gi|9945318 MAX binding protein [Homo sapiens]
          Length = 582

 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 60/182 (32%), Positives = 75/182 (41%), Gaps = 37/182 (20%)

Query: 846  QNPRAEAPCYVSHPSPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPTSV 905
            + PR EAP     P P+ P  P P PP     PA +   P+PV +    PQPLPP P  +
Sbjct: 56   EEPRMEAP-----PLPLSPPAPPPAPPPPLATPAPLTVIPIPVVT--NSPQPLPP-PPPL 107

Query: 906  PPAAFPAPLVTPMVALV------------LPNY-LFPTPSS-YPYGALQTPAEGPPTPAS 951
            P AA P PL     ALV            LP+    PTP+   P      P  G P P  
Sbjct: 108  PAAAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQ 167

Query: 952  HSPSPSLPALAPSP-------PHRPDSPLFNSRCSSPLQLNLLQLEELPRAEGAAVAGGP 1004
              P+P L  +AP P       P +P  P   +       L L   EE+  +E     GG 
Sbjct: 168  PLPTPVL-TIAPHPGVQPQLAPQQPPPPTLGT-------LKLAPAEEVKSSEQKKRPGGI 219

Query: 1005 GS 1006
            G+
Sbjct: 220  GT 221



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 53/171 (30%), Positives = 70/171 (40%), Gaps = 20/171 (11%)

Query: 884  YPLPVFSPRGGPQPLPPAPTSVPPAAFPAPLVTPMVALVLP-----NYLFPTPSSYPYGA 938
            + LPV  PR    PLP +P + PPA  P PL TP    V+P     N   P P   P  A
Sbjct: 51   HTLPVEEPRMEAPPLPLSPPAPPPAP-PPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPA 109

Query: 939  LQTPAEGPPTPASHSPSPSLPALAPSP-PHRPDSP-----LFNSRCSSPLQLNLLQLEEL 992
               P    P   +   +P L    P+P P RP  P     L +S+ + P   +   L+ L
Sbjct: 110  AAQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPL 169

Query: 993  PRAEGAAVAGGPG-----SSAGPPPPSAEAAEPEARLAEVTESSNQDALSG 1038
            P      +A  PG     +   PPPP+      +   AE  +SS Q    G
Sbjct: 170  P-TPVLTIAPHPGVQPQLAPQQPPPPTLGTL--KLAPAEEVKSSEQKKRPG 217



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 24/62 (38%), Positives = 28/62 (45%), Gaps = 4/62 (6%)

Query: 861 PVPPSTPWPTPPATTPFP--AVVQPYPLPVFSPRGGPQPLPPAPTSVPPAAFPAPLVTPM 918
           P P +TP P PP   P P    + P  LPV   +  PQ   P P   PP A PA  + P 
Sbjct: 369 PPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQ--PQQKTPLPAPPPPPAAPAQTLVPA 426

Query: 919 VA 920
            A
Sbjct: 427 PA 428



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 108/478 (22%), Positives = 168/478 (35%), Gaps = 72/478 (15%)

Query: 472 TPPAPSPAPSLDTDIQELSEQIHRLLLQPVHSPSPTGLCGVGAVT-SPGPLHSPGSSSDS 530
           +PPAP PAP                   P+ +P+P  +  +  VT SP PL  P     +
Sbjct: 68  SPPAPPPAPP-----------------PPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAA 110

Query: 531 NGGDAEGPGPPAPVTFQQICKDVHLVKHQGQQLFIESRARPQSRPRLPATGTFK-AKALP 589
                  P  PA V    +            Q+   +   P S+  +P  G+ K  + LP
Sbjct: 111 AQPLPLAPRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLP 170

Query: 590 CQ----SPDPELEAGSAPVQAP------LALVPEE-----AERKEASSCSYQQI-NCLDS 633
                 +P P ++   AP Q P      L L P E      ++K       +++ N L+ 
Sbjct: 171 TPVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEVKSSEQKKRPGGIGTREVHNKLEK 230

Query: 634 ILR-YLESC------NLPSTTKRKCASSSSYTTSSASDDDRQRTGPVSVGTKKDPPSAAL 686
             R +L+ C      N+P+   +K ++ S   T+       +R        + +     L
Sbjct: 231 NRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRK-----EKEYEHEMERL 285

Query: 687 SGEG-ATPRKEPVVGGTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPESDIIMME 745
           + E  AT ++   +   LS      + + V+  T Q            +     D  M E
Sbjct: 286 AREKIATQQRLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNIDEDMEE 345

Query: 746 DLPGLAP-----GPAP----SPAPSPTVAPDPAPDAYRP----VGLTKAVLSLHTQKEEQ 792
           D  GL P      P P    S  P P+  P P P    P    V L  A L +  Q+ +Q
Sbjct: 346 DRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPLPPHPHPHPHSVALPPAHLPVQQQQPQQ 405

Query: 793 AFLSRFRDLGRLRGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAK--RSRHH--QNP 848
                           +   AP+ L       G       H   + A   ++ +H  Q P
Sbjct: 406 KTPLPAPPPPPAAPAQTLVPAPAHLVATA---GGGSTVIAHTATTHASVIQTVNHVLQGP 462

Query: 849 RAEAPCYVSHPSPVPPSTPWPTPPATTPFPAV-VQPYPLPVFSPRGGPQPLPPAPTSV 905
             +   +++H +P  PS      PAT P   + V P  L   +  G   PL P P +V
Sbjct: 463 GGK---HIAHIAPSAPSPAVQLAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVAV 517



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 27/75 (36%), Positives = 34/75 (45%), Gaps = 6/75 (8%)

Query: 895 PQPLPPAPTSVPPAAFPAPLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSP 954
           PQP     T  PP+  PAPL  P      P+ +   P+  P    Q P +  P PA   P
Sbjct: 359 PQPELLKSTLPPPSTTPAPL--PPHPHPHPHSVALPPAHLPVQQ-QQPQQKTPLPAP-PP 414

Query: 955 SPSLPA--LAPSPPH 967
            P+ PA  L P+P H
Sbjct: 415 PPAAPAQTLVPAPAH 429



 Score = 31.2 bits (69), Expect = 6.7
 Identities = 32/113 (28%), Positives = 40/113 (35%), Gaps = 14/113 (12%)

Query: 808 DSSSTAPSALGERGCHH-------GPAPPSRRHHCRSKAKRSRHHQNPRAEAPCYVSHPS 860
           D +ST+ ++ GE            G  PP   H  + +  +S         AP    HP 
Sbjct: 325 DQASTSTASEGEDNIDEDMEEDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAPL-PPHPH 383

Query: 861 PVPPSTPWPTPPATTPF----PAVVQPYPLPVFSPRGGPQPLPPAPTSVPPAA 909
           P P S     PPA  P     P    P P P   P    Q L PAP  +   A
Sbjct: 384 PHPHSVA--LPPAHLPVQQQQPQQKTPLPAPPPPPAAPAQTLVPAPAHLVATA 434


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 132/562 (23%), Positives = 181/562 (32%), Gaps = 104/562 (18%)

Query: 503  SPSPTGLCGVGAVTSPGPLHSPGSSSDSNGGDAEGPGPPAPVTFQ-------QICKDVHL 555
            SPSP G+  V   T   P     +  D+  G+   P  P   +F        Q  KD   
Sbjct: 793  SPSPLGV-SVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPA 851

Query: 556  VKHQGQQLFIESRARPQSRPRLPATGTFKAKAL---PCQSPDPELEAGSAPVQAPLALVP 612
              H        +   P+  P   A      K +   P ++P P +     P + P    P
Sbjct: 852  TTHS------PTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAP 905

Query: 613  EEAERKEASSCSYQQINCLDSILRYLESCNLPSTTKRKCASSSSYTTSSASDDDRQRTGP 672
            ++A     +S S ++     +         +P++   K A      T  A+     + GP
Sbjct: 906  KQAPALSMTSSSPKKARATPA------PKGIPASPSPKGAP-----TPPAATPPSPKGGP 954

Query: 673  VSVGTKKDPPSAALSGEGATPRKEPVVGGTLSPLALANKAESVVSVTSQCSFSSTIVHVG 732
             +   K  P   A     ATP      GG  +P           +  S     +T    G
Sbjct: 955  ATPSPKWAPTPPA-----ATPPSPK--GGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007

Query: 733  DKKPPESDIIMMEDLPGLAPGPAPSPAPSPTVAPDP--APDAYR-PVGL-TKAVLSLHTQ 788
               PP       +  P   P P  +  P     P P  +P A   P G  T    +L + 
Sbjct: 1008 APTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP 1067

Query: 789  KEEQAFLSRFRDLGRLRGLDS--SSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQ 846
            K   A  S       L+G  +  ++T PS  G      GPA PS +              
Sbjct: 1068 KGGPATPS-------LKGAPTPPAATPPSPKG------GPATPSPKG------------- 1101

Query: 847  NPRAEAPCYVSHPSP-----VPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPPA 901
               A  P   + PSP      PP    PT PA TP             SP+GG    PP 
Sbjct: 1102 ---APMPPAATPPSPKGGLATPPHKGAPTTPAATPP------------SPKGGLATPPPK 1146

Query: 902  PTSVPPAAFPAPLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLPAL 961
                 PAA P    +P   L  P          P GA  TPA  PP+P     +PS    
Sbjct: 1147 GAPTTPAATPP---SPKGGLATPP---------PKGAPTTPAATPPSPKGGLATPSPKGA 1194

Query: 962  APSPPHRPDSPLFNSRCSSPLQLNLLQLEELPRAEGAAVAGGPGS-----SAGPPPPSAE 1016
              +P   P SP       SP           P  +G      P       +A PP P   
Sbjct: 1195 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1254

Query: 1017 AAEPEARLAEVTESSNQDALSG 1038
             A P  + A    ++   +L G
Sbjct: 1255 PATPPPKGAPTPPAATPPSLKG 1276



 Score = 63.9 bits (154), Expect = 9e-10
 Identities = 106/401 (26%), Positives = 141/401 (35%), Gaps = 58/401 (14%)

Query: 653  SSSSYTTSSASDDDRQRTGPVSVGTKKDPPSAALSGEGATPRKEPVVGGTLSPLALANKA 712
            +SS  T +  +D        VS  TK+ P     +G   TP     +   +SP+  +   
Sbjct: 781  ASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPD-TPIGN--LSSPVSPVEASFLP 837

Query: 713  ESVVSVTSQCSFSSTIVHVGDKKP---PESDIIMMEDLPGLAPGPAPSPAPSPTVAPDPA 769
            E+ +S        +T        P   P    +      G+   P  +P PS    P P 
Sbjct: 838  ENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPK 897

Query: 770  PDAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRGLDSSST-----APSALGERGCHH 824
                 P       LS+ +   ++A     R     +G+ +S +      P A        
Sbjct: 898  EGPATPAPKQAPALSMTSSSPKKA-----RATPAPKGIPASPSPKGAPTPPAATPPSPKG 952

Query: 825  GPAPPSRRHHCRSKA------KRSRHHQNPR-AEAPCYVSHPSPVP-PSTPWP----TPP 872
            GPA PS +      A      K      +P+ A  P   + PSP   P+TP P    TPP
Sbjct: 953  GPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPP 1012

Query: 873  ATTPFPAVVQPYPLPVFSPRGGPQP----LPPAPTSVPPAAFPAPLVTPMVALVLPNYLF 928
            A TP        P P  SP   P P     PPA T   P   PA    P  A   P    
Sbjct: 1013 AVTP--------PSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATL 1064

Query: 929  PTPSSYP-----YGALQTPAEGPPTPASHSPSPSLPALAPSPP-HRPDSPLFNSRCSSPL 982
            P+P   P      GA   PA  PP+P     +PS P  AP PP   P SP      ++P 
Sbjct: 1065 PSPKGGPATPSLKGAPTPPAATPPSPKGGPATPS-PKGAPMPPAATPPSP--KGGLATPP 1121

Query: 983  QLNLLQLEELPRAEGAAVAGGPGSSAGPPP---PSAEAAEP 1020
                   +  P    A      G  A PPP   P+  AA P
Sbjct: 1122 H------KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1156



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 105/438 (23%), Positives = 148/438 (33%), Gaps = 74/438 (16%)

Query: 693  PRKEPVVGGTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPESDIIMMEDLPGLAP 752
            P+  PV  GTL+ L L   A     V      +           P + +++  ++P   P
Sbjct: 685  PKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCA---------PLATLVLAPEIPKSVP 735

Query: 753  GPAPSPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRGLDSSST 812
             P+  PA +P     P       +  T A+  + +  +E        D G      S  T
Sbjct: 736  SPSLPPAGTP-----PGTKKVDGISHTSALAPVASSPKE----CPTEDSGASATASSKGT 786

Query: 813  ------APSALGERGCHHGPAPPSRR---------HHCRSKAKRSRHHQNPRAEAPCYVS 857
                  +PS LG         PP+++          +  S          P        S
Sbjct: 787  LTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGS 846

Query: 858  HPSPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPTSVPPA--------- 908
              SP    +P P  P   P P+ V P      SP+G    LPP  T  P           
Sbjct: 847  KDSPATTHSPTPPSPKGAPTPSAVTP-----LSPKG--VTLPPKETPTPSVVNLPFPKEG 899

Query: 909  -AFPAPLVTPMVALV--LPNYLFPTP-------SSYPYGALQTPAEGPPTPASHSPSPSL 958
             A PAP   P +++    P     TP       S  P GA   PA  PP+P     +PS 
Sbjct: 900  PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPS- 958

Query: 959  PALAPSPP-HRPDSPLFNSRCSSPLQLNLLQLEELPRAEGAAVAGGPGSSAGPP---PPS 1014
            P  AP+PP   P SP       SP           P  +G      P  +  PP   PPS
Sbjct: 959  PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPS 1018

Query: 1015 ---AEAAEPEARLAEVTESSNQDALSGSSDLLELLLQEDSRSGTGSAASGSLGSGLGSGS 1071
               + AA P  + A    ++   +  GS     L        G  +  + +L S  G G 
Sbjct: 1019 PKGSPAATPFPKGASTPPAATPPSPKGSPAATPL------PKGAPTTPAATLPSPKG-GP 1071

Query: 1072 GSGSHEGGSTSASITRSS 1089
             + S +G  T  + T  S
Sbjct: 1072 ATPSLKGAPTPPAATPPS 1089



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 157/652 (24%), Positives = 207/652 (31%), Gaps = 151/652 (23%)

Query: 474  PAPSPAPSLDTDIQELSEQIHRLLLQPVH---SPSPTGLCGVGAVTSPGPLHSPGSSSDS 530
            PAP  AP+L   +   S +  R    P     SPSP G     A T P P   P + S  
Sbjct: 903  PAPKQAPALS--MTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPK 960

Query: 531  NGGDAEGPGPPAPVTFQQICKDVHLVKHQGQQLFIESRARPQSRPRLPATGTFKAKALP- 589
                     PP+P                 +       A P S    PAT + K    P 
Sbjct: 961  WAPTPPAATPPSPKGGP--------ATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPP 1012

Query: 590  -CQSPDPELEAGSAP----VQAPLALVPEEAERKEASSCSYQQINCLDSILRYLESCNLP 644
                P P+    + P       P A  P   +   A++        L        +  LP
Sbjct: 1013 AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATP-------LPKGAPTTPAATLP 1065

Query: 645  STTKRKCASS-SSYTTSSASDDDRQRTGPVSVGTKKDPPSAALSGEGATPRKEPVVGGTL 703
            S        S     T  A+     + GP +   K  P   A     ATP      GG  
Sbjct: 1066 SPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPA-----ATPPSPK--GGLA 1118

Query: 704  SPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPESDIIMMEDLPGLAPGPAPSPAPSPT 763
            +P    +K        +  S    +     K  P +         G    P P  AP+  
Sbjct: 1119 TP---PHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1175

Query: 764  VAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRGLDSSSTAPSALG----- 818
             A  P+P         K  L+  + K                    ++T PS  G     
Sbjct: 1176 AATPPSP---------KGGLATPSPKGAPT--------------TPAATPPSPKGGLATP 1212

Query: 819  -ERGCHHGPA--PPSRRHHCRSKAKRSRHHQNPRAEAPCYVSHPSPVPPSTPWPTPPATT 875
              +G    PA  PPS +    + + +      P A  P     P+  PP    PTPPA T
Sbjct: 1213 SPKGAPTTPAATPPSPKGGLATPSPKGAP-TTPAATPPSPKGGPATPPPKGA-PTPPAAT 1270

Query: 876  P----------------FPAVVQPYPLPVFSPRGGPQPLPPAPTSVPPAAFPA------- 912
            P                 PAVV P      SP+GGP   PP     PPAA P        
Sbjct: 1271 PPSLKGGLATPPHKGAPNPAVVTPP-----SPKGGPATSPPKGAPTPPAATPPSPKGSPG 1325

Query: 913  ----------PLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPA---SHSPSPSL- 958
                      P VTP      P     TPSS       +  EGP  PA   SH   P++ 
Sbjct: 1326 TPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT 1385

Query: 959  -------------------PALAP-SPPHRPDSPLFNSRCSSPLQLNL-------LQLEE 991
                               PA+ P SP   P +P+     ++P + +L       + L++
Sbjct: 1386 PPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKK 1445

Query: 992  LPRAEGAAVAGGPG--SSAGPP------PPSAEAAEPEARLAEVTESSNQDA 1035
             P    +A  GGP   SS G P      PPS +  EP A     T SS + A
Sbjct: 1446 APAT--SAPKGGPATPSSKGDPTLPAVTPPSPK--EPPAPKQVATSSSPKKA 1493



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 128/550 (23%), Positives = 187/550 (34%), Gaps = 111/550 (20%)

Query: 503  SPSPTGLCGVGAVTSPGPLHSPGSSSDSNGGDAEGPGPPAPVTFQQICKDVHLVKHQGQQ 562
            +PSP G     A T P P   P +           P PPA  T   +   +    H+G  
Sbjct: 1234 TPSPKGAPTTPAATPPSPKGGPATPPPKGA-----PTPPA-ATPPSLKGGLATPPHKGAP 1287

Query: 563  LFIESRARPQSRPRLPATGTFKAKALP--CQSPDPELEAGSAPVQA---PLALVPEEAER 617
                +   P S    PAT   K    P     P P+   G+ P +    P A+ P   + 
Sbjct: 1288 N--PAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG 1345

Query: 618  KEASSCSYQQINCLDSILRYLESCNLPSTTKRKCASSSSYTTSSASDDDRQRTGPVSVGT 677
                                     LP+TT    +S    TT S+ +      GP     
Sbjct: 1346 TPT----------------------LPATTP---SSKGGPTTPSSKE------GPT---- 1370

Query: 678  KKDPPSAALSGEGA------TPRKEPVV----GGTLSP--LALANKAESVVSVTSQCSFS 725
               PP+A  S +G       +P++ P +    G   SP  + L+ K      VT + + +
Sbjct: 1371 ---PPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAAT 1427

Query: 726  STIVHVGDKKPPESDIIMMEDLPGLAP---GPA-PSPAPSPTVAPDPAPDAYRPVGLTKA 781
             +    GD  PP    + ++  P  +    GPA PS    PT+ P   P + +     K 
Sbjct: 1428 PS---KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL-PAVTPPSPKEPPAPKQ 1483

Query: 782  VLSLHTQKEEQAFLSRFRDLGRLRGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKR 841
            V +  + K+  A  +             + T P+ +        PA PS R    +    
Sbjct: 1484 VATSSSPKKAPATPAPM----------GAPTLPAVIPSSP-KEVPATPSSRRDPIAPTAT 1532

Query: 842  SRHHQNPRAEAPCYVSHPSPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPPA 901
                + P   AP      + +PP+   P+P  T   PA+  P   P  +P       PPA
Sbjct: 1533 LLSKKTPATLAP----KEALIPPAMTVPSPKKT---PAIPTPKEAPA-TPSSKEASSPPA 1584

Query: 902  PTSVPPAAFPAPLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLPAL 961
             T       P+P             L P   + P     +P E P  PA   PSP     
Sbjct: 1585 VTPSTYKGAPSP----------KELLIPPAVTSP-----SPKEAPTPPAVTPPSPEKGPA 1629

Query: 962  APSPPHRPDSPLFNSRCSSPLQLNLLQLEELPRAEGAAVAGGPGSSAGPPPPSAEAAEPE 1021
             P+P   P SP       S L+ +      +    GA V   P +S G P      A  E
Sbjct: 1630 TPAPKGTPTSPPVT---PSSLKDSPTSPASVTCKMGATV---PQASKGLPAKKGPTALKE 1683

Query: 1022 ARLAEVTESS 1031
              +A   ES+
Sbjct: 1684 VLVAPAPEST 1693



 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 140/650 (21%), Positives = 202/650 (31%), Gaps = 137/650 (21%)

Query: 472  TPPAPSPAPSLDTDIQELSEQIHRLLLQPVHSPSPTGLC----GVGAVTSPGPLHSPGSS 527
            TPP+P   P+L       S +           P+P        G  A+T P P   P   
Sbjct: 1339 TPPSPKGTPTLPATTP--SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIP 1396

Query: 528  SDSNGGDAEGPG---------PPAPVTFQQICKDVHLVKHQGQQLFIESRARPQSRPRLP 578
            S    GD   P          P  PVT     ++      +G          P S  + P
Sbjct: 1397 SPK--GDPTSPAVIPLSPKKAPATPVT-----REGAATPSKGD--LTPPAVTPVSLKKAP 1447

Query: 579  ATGTFKA-KALPCQSPDPELEAGSAPVQ----APLALVPEEAERKEASSCSYQQINCLDS 633
            AT   K   A P    DP L A + P      AP  +    + +K  ++ +      L +
Sbjct: 1448 ATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPA 1507

Query: 634  ILRYLESCNLPSTTKRKCASSSSYTTSSASDDDRQRTGPVSVGTKKDPPSAALSGEGATP 693
            ++        PS+ K   A+ SS          R    P +    K  P+     E   P
Sbjct: 1508 VI--------PSSPKEVPATPSSR---------RDPIAPTATLLSKKTPATLAPKEALIP 1550

Query: 694  RKEPVVGGTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPESDIIMMEDLPGLAPG 753
                V     +P     K       + + S    +     K  P    ++   +P     
Sbjct: 1551 PAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELL---IPPAVTS 1607

Query: 754  PAPSPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRGLDSSSTA 813
            P+P  AP+P     P+P+        K      T        S  +D         S T+
Sbjct: 1608 PSPKEAPTPPAVTPPSPEKGPATPAPKG-----TPTSPPVTPSSLKD---------SPTS 1653

Query: 814  PSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEAPCYVSHPSPVPPSTPWPTPPA 873
            P+++    C  G   P       +K       + P A     V+   P P STP  T P 
Sbjct: 1654 PASVT---CKMGATVPQASKGLPAK-------KGPTALKEVLVA---PAPESTPIITAPT 1700

Query: 874  T----TPFPAVVQPYPLPVFSPRGG---------PQPL-------------------PPA 901
                 T   +   P   P  S + G         P PL                   P  
Sbjct: 1701 RKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKG 1760

Query: 902  PTSVPPAAFPAPLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLPAL 961
            P + P +    PL       VLP          P  A  + A  PP     +PSP +P L
Sbjct: 1761 PLAPPESKASTPLTAAAFEKVLPK---------PESASVSAAPSPPVSLPLAPSP-VPTL 1810

Query: 962  APSPPHRPDSPLFNSRCSSPLQLNLLQLEELPRAEGAAVAGG-----------PGSSAGP 1010
             P     P SP       S       + E LP      ++GG              SAG 
Sbjct: 1811 PPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGI 1870

Query: 1011 PPPSAEAAEPEARLAEVTESSNQDALSGSSD--LLELLLQEDSRSGTGSA 1058
            P P+  A +P      VT+++        SD  + EL  Q+ +++ T  A
Sbjct: 1871 PVPTPSAKQP------VTKNNKGSGTESDSDESVPELEEQDSTQATTQQA 1914



 Score = 34.3 bits (77), Expect = 0.79
 Identities = 43/165 (26%), Positives = 55/165 (33%), Gaps = 15/165 (9%)

Query: 864  PSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPTSVPPAAFPAPLVTPMVALVL 923
            P+T    P        +     L V +  G P P  P P S  P   P            
Sbjct: 10   PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPS 69

Query: 924  PNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLPALAPSPPHRPDSPLFNSRCSSPLQ 983
            P+ +  TP   P+     P     T      +P  P   P+    P SP   +  +SP+ 
Sbjct: 70   PSTIASTPLEVPF-----PQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALA-LASPMI 123

Query: 984  LNLLQLEELPRAEGAAVAGGP----GSSAGPP-----PPSAEAAE 1019
               L+      A  A VA  P     SSA PP     PPS   AE
Sbjct: 124  APTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAE 168



 Score = 30.8 bits (68), Expect = 8.8
 Identities = 44/156 (28%), Positives = 59/156 (37%), Gaps = 37/156 (23%)

Query: 860 SPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPTSVP----PAAFPA--P 913
           SP P  +   + P   PFP       LP+ +        P APT +P    P   PA   
Sbjct: 65  SPFPSPSTIASTPLEVPFPQSSSGTALPLGT-------APEAPTFLPNLIGPPISPAALA 117

Query: 914 LVTPMVALVLPNYLFPTPSSYPYGAL--------QTPAEGPP----TPASHSPSPSLPAL 961
           L +PM+A  L      TPSS    AL        Q  +  PP    +P S + + S   +
Sbjct: 118 LASPMIAPTLKG----TPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVI 173

Query: 962 APSPPHRPDSPLFNSRCSSPLQLNLLQLEELPRAEG 997
             S P  P  P  N        LN +  E +P  +G
Sbjct: 174 TLSAPIAPSEPKTN--------LNKVPSEVVPNPKG 201


>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
          Length = 1312

 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 99/404 (24%), Positives = 149/404 (36%), Gaps = 72/404 (17%)

Query: 500 PVHSPSPTGLCGVGAVTSPGPLHSPGSSSDSNGGDAEGPGPPAPVTFQQICKDVHLVKHQ 559
           P   P+P+      A +SP P  SP SSS S       P PPAP   +    D++   H 
Sbjct: 184 PAPPPAPSS-----ASSSPSP--SPSSSSPSPPPPPPPPAPPAPPAPR---FDIYDPFHP 233

Query: 560 GQQLFIESRARPQSRPRLPATGTFKAKALPCQSPDPELEAGSAPVQAPLALVPEEAERKE 619
             + +    A  Q       TG+  + +    SP+ E E              EE E +E
Sbjct: 234 TDEAYSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEE--------------EEEEEEE 279

Query: 620 ASSCSYQQINCLDSILRYLESCNLPSTTKRKCASSSSYTTSSASDDDRQRTGPV-SVGTK 678
                 ++     SI R  E+    +      + S  +    +   D Q T P  + GT 
Sbjct: 280 EEEDEEEEEGLSQSISRISETL---AGIYDDNSLSQDFPGDESPRPDAQPTQPTPAPGT- 335

Query: 679 KDPPSAALSGEGATPRKEPVVGGTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPE 738
             PP    +      R+   V GT +      K    V      +    ++  GD +  E
Sbjct: 336 --PPQVDSTRADGAMRRRVFVVGTEAEACREGKVSVEVVTAGGAALPPPLLPPGDSEIEE 393

Query: 739 SDIIMMEDLPGLA-----PG-----PAPSPAPSPTVAPDPAPDAYR-PVGLTKAVLSLHT 787
            +I+  E+ P LA     PG     P P+ + +PT  P P P A R P G     LSLH 
Sbjct: 394 GEIVQPEEEPRLALSLFRPGGRAARPTPAASATPTAQPLPQPPAPRAPEG--DDFLSLHA 451

Query: 788 QKEEQAFLSRFRDLG-----------RLRGLDSSSTAPSALGERGCHHGPA--------- 827
           + + +  L    DLG           R  GLD      +   ER     P+         
Sbjct: 452 ESDGEGALQ--VDLGEPAPAPPAADSRWGGLDLRRKILTQRRERYRQRSPSPAPAPAPAA 509

Query: 828 ---PPSRRHHCRSKAKRSRHHQNPRAEAPCYVSHPSPVPPSTPW 868
              PP+R+   +S+ +R R  +   A +    + P+P  P++PW
Sbjct: 510 AAGPPTRK---KSRRERKRSGEAKEAASSSSGTQPAPPAPASPW 550



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 28/111 (25%), Positives = 41/111 (36%), Gaps = 1/111 (0%)

Query: 929  PTPSSYPYGALQTPAEGPPTPASHSPSPSLPALAPSPPHRPDSPLFNSRCSSPLQLNLLQ 988
            P P   P  A  +P+  P + +   P P  P   P+PP  P   +++    +    +   
Sbjct: 184  PAPPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPP-APRFDIYDPFHPTDEAYSPPP 242

Query: 989  LEELPRAEGAAVAGGPGSSAGPPPPSAEAAEPEARLAEVTESSNQDALSGS 1039
              E            P SSAG P P  E  E E    E  +   ++ LS S
Sbjct: 243  APEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQS 293



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 33/139 (23%), Positives = 51/139 (36%), Gaps = 20/139 (14%)

Query: 23  GGVPSPGPPQHRPCPGPSLADDTDANSNGSSGNESNGHESRGASQRSSHSSSSGNGKDSA 82
           G +    P    P P  S   +   +S G SG E  G  S+   +RS  +SSS + ++  
Sbjct: 708 GRLDKSDPRGPSPAPASSPKREVLYDSEGLSGEERGGKSSQKDRRRSGAASSSSSSREKG 767

Query: 83  L-----------------LETTESSKSTNSQSPSPPSSSIAYSLLSASSEQDNPSTSGCS 125
                              +   SSK       S PSS        +S    + S+S CS
Sbjct: 768 SRRKALDGGDRDRDRDRDRDRDRSSKKARPPKESAPSSGPPPKPPVSSGSGSSSSSSSCS 827

Query: 126 SEQSARARTQKELMTALRE 144
           S    + + Q ++   +RE
Sbjct: 828 SR---KVKLQSKVAVLIRE 843



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 37/148 (25%), Positives = 54/148 (36%), Gaps = 26/148 (17%)

Query: 937  GALQTPAEGPPTPASHSPSPSLPALAPSPPHRPDSPLFNSRCSSPLQLNLLQLEELPRAE 996
            GA +T   G    A    +P   A  P P   PDS   +S C +P +++ L  E     E
Sbjct: 958  GAEETSWSGEERAAKVPSTPPPKAAPPPPALTPDSQTVDSSCKTP-EVSFLPEE---ATE 1013

Query: 997  GAAVAGGPGSSAGPPPPSAEAAEPEARLAEVTESSNQDALSGSSDLLELLLQEDSRSGTG 1056
             A V GG            E  E E    E  E   Q A +             + + T 
Sbjct: 1014 EAGVRGG---------AEEEEEEEEEEEEEEEEEEQQPATT-------------TATSTA 1051

Query: 1057 SAASGSLGSGLGSGSGSGSHEGGSTSAS 1084
            +AA  +  S   +   SG+ +G ++  S
Sbjct: 1052 AAAPSTAPSAGSTAGDSGAEDGPASRVS 1079


>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
            1 [Homo sapiens]
          Length = 1250

 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 75/308 (24%), Positives = 110/308 (35%), Gaps = 50/308 (16%)

Query: 752  PGPAPSPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRG----- 806
            P P P P P P   P P P    P   + A + +     + + ++R ++  +  G     
Sbjct: 632  PPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFV-----KYSTITRLQNASQHSGALFKP 686

Query: 807  -----LDSSSTAPSAL----GERGCHHGPAPPSRRHHCRSKAKRSRHHQN-PRAEAPC-- 854
                 + S S  P  L    G       P PP       ++ K +    + P+  AP   
Sbjct: 687  PTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPP 746

Query: 855  ----YVSHPSPVPPSTPWPTPPATTPFPAVVQPYPL-------------PVFSPRGGPQP 897
                 V H + V P TP P PP   P P    P PL             PV +    P P
Sbjct: 747  LKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTP 806

Query: 898  LPPAPTSVPPAAFPAPLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPS 957
             PP P +    AFPA  + P      P    P P           A+ PP+P S  PS  
Sbjct: 807  TPPVPPAKKQPAFPASYIPPSP----PTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPS-V 861

Query: 958  LPALAPSPPHRPDSPLFNSRCSSPLQLNLL-----QLEELPRAEGAAVAGGPGSSAGPPP 1012
            +  +A   P  P  P   S+   P+  N+       ++  P+ + +++   P     PPP
Sbjct: 862  VKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIP-VPSPDFPPPP 920

Query: 1013 PSAEAAEP 1020
            P +    P
Sbjct: 921  PESSLVFP 928



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 66/261 (25%), Positives = 97/261 (37%), Gaps = 53/261 (20%)

Query: 736 PPESDIIMMEDLPGLAPGPAPSPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFL 795
           PP   I  ++ +  +AP   P P P P   P  AP   +P+    A  S  T        
Sbjct: 744 PPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPP--KPLVTIPAPTSTKT-------- 793

Query: 796 SRFRDLGRLRGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEAPCY 855
                   +  + + +  P+          P PP+++      +     +  P    P  
Sbjct: 794 --------VAPVVTQAAPPTPT-------PPVPPAKKQPAFPAS-----YIPPSPPTP-- 831

Query: 856 VSHPSPVPPST--------PWPTPPATTPFPAVVQ----PYPLPVFSPRGGPQPLPPAPT 903
              P PVPP T          P P   +P P+VV+     +P P   P    QPL P P 
Sbjct: 832 ---PVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPA 888

Query: 904 SVPPAAFPAPLVTPM---VALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLPA 960
           +V P + PA    P     ++ +P+  FP P   P  +L  P   PP+P    P P  P 
Sbjct: 889 NVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPP--PESSLVFPPP-PPSPVPAPPPPPPPT 945

Query: 961 LAPSPPHRPDSPLFNSRCSSP 981
            +P+P          S+ SSP
Sbjct: 946 ASPTPDKSGSPGKKTSKTSSP 966



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 73/273 (26%), Positives = 94/273 (34%), Gaps = 40/273 (14%)

Query: 748  PGLAPGPAPSPAPSPTVAPD------PAPDAYRPVG--LTKAVLSLHTQ-----KEEQAF 794
            P   P P P PAP P  AP       PAP + + V   +T+A     T      K++ AF
Sbjct: 760  PPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAF 819

Query: 795  LSRFRDLGRLRGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEAPC 854
             + +  +            P  L ++       PPS      S  K+      P    P 
Sbjct: 820  PASY--IPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPA 877

Query: 855  YVSHP-SPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQP------LPPAPTSVPP 907
              S P  PVP +    +PPA    P   QP  +PV SP   P P       PP P S  P
Sbjct: 878  MESQPLKPVPANVAPQSPPAVKAKPKW-QPSSIPVPSPDFPPPPPESSLVFPPPPPSPVP 936

Query: 908  AAFPAPLVTPMVALVLPNYLFPTPSSYPYGALQTP-------AEGPPTPASHSPSPSLPA 960
            A  P P          P    PTP        +T         + PPTP  +S   S   
Sbjct: 937  APPPPP----------PPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSG 986

Query: 961  LAPSPPHRPDSPLFNSRCSSPLQLNLLQLEELP 993
                 P RP      S+ + P +      E LP
Sbjct: 987  AEHPEPKRPSVDSLVSKFTPPAESGSPSKETLP 1019



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 49/175 (28%), Positives = 55/175 (31%), Gaps = 54/175 (30%)

Query: 848 PRAEAPCYVSHPSPVPPSTPWPTPPATTPFPAVVQPYP----------LPVF-------- 889
           P+   P   S PSP  P  P P PP   P P    P P           P+F        
Sbjct: 613 PKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITR 672

Query: 890 ----SPRGG-----------------PQPLPPAPTSVPPAAFPAPLVTPMVALV------ 922
               S   G                 PQ L P    VPP   P P  TP  A+       
Sbjct: 673 LQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAP 732

Query: 923 ----LPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLPALAPSPPHRPDSPL 973
               LP +  P P    +         PPTP    P P +P  AP PP  P  PL
Sbjct: 733 CAPSLPQFSAPPPPLKIHQVQHITQVAPPTP---PPPPPIP--APLPPQAPPKPL 782



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 47/154 (30%), Positives = 58/154 (37%), Gaps = 27/154 (17%)

Query: 872  PATTPFPAVVQPYPLPVFSPRGGPQPLPPAPTSVPPAAFPAPLVT---PMVALVLPNYL- 927
            P  +P P +V PY     SP   P P PP P   PP   P PL +   P      P ++ 
Sbjct: 607  PPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVK 666

Query: 928  FPT-----PSSYPYGALQTPAEGPPTPASHSPSPSL----PALAPSPPHRPDSPLFNSRC 978
            + T      +S   GAL  P   PP   S S  P +      + P PP  P  P   S  
Sbjct: 667  YSTITRLQNASQHSGALFKPPT-PPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSA- 724

Query: 979  SSPLQLNLLQLEELPRAEGAAVAGGPGSSAGPPP 1012
                   + QL+  P A        P  SA PPP
Sbjct: 725  -------MAQLKPAPCAPSL-----PQFSAPPPP 746



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 67/291 (23%), Positives = 95/291 (32%), Gaps = 45/291 (15%)

Query: 705  PLALANKAESVVSVTSQCSFSSTIVHVGDKKPPESDIIMMEDLPGLAPGPAPSPAPSPTV 764
            P  +A ++   V    +   SS  V   D  PP  +  ++   P  +P PAP P P PT 
Sbjct: 887  PANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTA 946

Query: 765  APDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRGLDSSSTAPSALGERGCHH 824
            +  P PD     G   +  S    K+      R           +SS   S+  E   H 
Sbjct: 947  S--PTPDKSGSPGKKTSKTSSPGGKKPPPTPQR-----------NSSIKSSSGAE---HP 990

Query: 825  GPAPPSRRHHCRSKAKRSRHHQNPRAEAPCYVSHPSPVPPSTPWPTPPATTPFPAVVQ-- 882
             P  PS        +  S+      + +P   + P P  P  P     +    P V+Q  
Sbjct: 991  EPKRPS------VDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQG 1044

Query: 883  --PYPLPVFSPRGGPQ----PLPPAPTSVPPAAFPAPLVTPMVAL-------VLPNYLFP 929
                  PV S RG       P PP+ +  PP      L  P + +         P     
Sbjct: 1045 CVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVV 1104

Query: 930  TPSSYPYGALQTPAEGPPTPASHSPSPSL--------PALAPSPPHRPDSP 972
             P    +  +      PPT    + S  L        P +A   P  P SP
Sbjct: 1105 NPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSP 1155



 Score = 30.8 bits (68), Expect = 8.8
 Identities = 32/110 (29%), Positives = 44/110 (40%), Gaps = 16/110 (14%)

Query: 14   PRPGESFCPGGVPSPGPPQHRPCPGPSLADDTDANSNGSSGNESNGHESRGASQRSSHSS 73
            P P ES      P P P    P P P  A  T   S GS G            +++S +S
Sbjct: 918  PPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKS-GSPG------------KKTSKTS 964

Query: 74   SSGNGKDSALLETTESSKSTN-SQSPSP--PSSSIAYSLLSASSEQDNPS 120
            S G  K     +   S KS++ ++ P P  PS     S  +  +E  +PS
Sbjct: 965  SPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPS 1014


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 145/657 (22%), Positives = 209/657 (31%), Gaps = 183/657 (27%)

Query: 464  APLNEDVFTPPAPSP-APSLDTDIQELSEQIHRLLLQPVHSPSPTGLCGVGAVTSPGP-- 520
            +PL E   +PP  SP +P+L+T +    E      L P    SP         TSP P  
Sbjct: 513  SPLEESPLSPPEESPPSPALETPLSPPPEASP---LSPPFEESPLSPPPEELPTSPPPEA 569

Query: 521  --LHSPGSSSDSNGGDAEGPGPPAPVTFQQICKDVHLVKHQGQQLFIESRARPQSRPRLP 578
              L  P   S  +    E P  P P               +  +LF      P S P   
Sbjct: 570  SRLSPPPEESPMSPPPEESPMSPPP---------------EASRLFPPFEESPLSPP--- 611

Query: 579  ATGTFKAKALPCQSPDPELEAGSAPVQAPLALVPEEAERKEASSCSYQQINCLDSILRYL 638
                   +  P   P         P  +P++  PEE+        S  +++ L  + R  
Sbjct: 612  ------PEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVS--RLSPLPVVSRL- 662

Query: 639  ESCNLPSTTKRKCASSSSYTTSSASDDDRQRTGPVSVGTKKDPPSAALSGEGATPRKEPV 698
                          S     +  +   +   T P    ++  PP         +P   P 
Sbjct: 663  --------------SPPPEESPLSPPPEESPTSPPPEASRLSPPPED------SPTSPPP 702

Query: 699  VGGTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPESDIIMMEDLPGLAP---GPA 755
                 SP       +S++S+  +                ES ++ + + P L P   GP 
Sbjct: 703  EDSPASP----PPEDSLMSLPLE----------------ESPLLPLPEEPQLCPRSEGPH 742

Query: 756  PSPAPS-PTVAPDP-----APDAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRGLDS 809
             SP P  P ++P P     +P A  P         L  Q EE    +           + 
Sbjct: 743  LSPRPEEPHLSPRPEEPHLSPQAEEP--------HLSPQPEEPCLCAV---------PEE 785

Query: 810  SSTAPSALGERGCHHGPAP---------------PSRRHHCRSKAKRSRHHQNPRAEAPC 854
               +P A    G H  P P               P     C S  +    H +P++E PC
Sbjct: 786  PHLSPQA---EGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSP-QPEESHLSPQSEEPC 841

Query: 855  YV-----SHPSPV---PPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQ---------- 896
                   SH SP    PP +P P  P   P      P  LP+F P G P           
Sbjct: 842  LSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPA-PEELPLFPPPGEPSLSPLLGEPAL 900

Query: 897  ---------------PLPPA------PTSVPPAAFPAPLVTPMVALVLPNYLFPTPS-SY 934
                           PL P+      P  +PP   P PL +P++    P  L P     Y
Sbjct: 901  SEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPL-SPIITAAAPPALSPLGELEY 959

Query: 935  PYGA--------------LQTPAEGPPTPASHSPSPSLPALAPSPPHRPDSPLFNSRCSS 980
            P+GA              L+TP   PP      P P  P + P  P  P  P      +S
Sbjct: 960  PFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGP------AS 1013

Query: 981  PLQLNLLQLEELPRAEGAAV-AGGPGSSAGPPPPSAEAAEPEARLAEVTESSNQDAL 1036
            P+ +  L  +  P  + + V    P S   PP        P + + +V   S++  L
Sbjct: 1014 PILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAEL 1070



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 85/307 (27%), Positives = 114/307 (37%), Gaps = 56/307 (18%)

Query: 732  GDKKPPESDIIMMEDLPGLAPGPAPSP-APSPTVAP-DPAPDAYRPVGLTKAVLSLHTQK 789
            G +  P+ +  + E++P L P P  SP +P P  +P  P P+A R          L    
Sbjct: 423  GVQLEPQLEAPLNEEMP-LLPPPEESPLSPPPEESPTSPPPEASR----------LSPPP 471

Query: 790  EEQAFLSRFRDLGRLRGLDSSSTAPSALG-ERGCHHGPAPPSRRHHCRSKAKRSRHHQNP 848
            EE                  +S  P AL   R     P  P       S    S    +P
Sbjct: 472  EEL----------------PASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPF-SP 514

Query: 849  RAEAPCYVSHPSPVPPS----TPWPTPPATTPF-------PAVVQPYPLPVFSPRGGPQP 897
              E+P  +S P   PPS    TP   PP  +P        P    P  LP  SP      
Sbjct: 515  LEESP--LSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPT-SPPPEASR 571

Query: 898  LPPAPTSVPPAAFPAPLVTPMVALVLPNYLFP----TPSSYPYGALQTPAEGPPTPASHS 953
            L P P   P +  P P  +PM      + LFP    +P S P    ++P   PP  +  S
Sbjct: 572  LSPPPEESPMS--PPPEESPMSPPPEASRLFPPFEESPLSPP--PEESPLSPPPEASRLS 627

Query: 954  PSPSLPALAPSPPHRPDSPLFNSRCSSPLQLNLLQLEELPRAEGAAVAGGPGSSAGPPPP 1013
            P P    ++P P   P SP       SPL + + +L   P  E + ++  P  S   PPP
Sbjct: 628  PPPEDSPMSPPPEESPMSPPPEVSRLSPLPV-VSRLS--PPPEESPLSPPPEESPTSPPP 684

Query: 1014 SAEAAEP 1020
             A    P
Sbjct: 685  EASRLSP 691



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 54/193 (27%), Positives = 75/193 (38%), Gaps = 20/193 (10%)

Query: 848  PRAEAPCYVSHPSPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGP---QPLPPAPTS 904
            P  E+P  +S P    P++P P     +P P  +   PLP       P    PL P P  
Sbjct: 443  PPEESP--LSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEE 500

Query: 905  VPPAAFPAPLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLPALAPS 964
             P +  P P  +P   L   + L P   S P  AL+TP   PP  +  SP      L+P 
Sbjct: 501  SPLS--PPPESSPFSPLE-ESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPP 557

Query: 965  PPHRPDSPLFNSRCSSPLQLNLLQLEELPRAEGAAVAGGPGSSAGPPPPSAEAAEPEARL 1024
            P   P SP        P + + L     P  E + ++  P  S   PPP A    P    
Sbjct: 558  PEELPTSP--------PPEASRLS----PPPEESPMSPPPEESPMSPPPEASRLFPPFEE 605

Query: 1025 AEVTESSNQDALS 1037
            + ++    +  LS
Sbjct: 606  SPLSPPPEESPLS 618



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 171/731 (23%), Positives = 238/731 (32%), Gaps = 139/731 (19%)

Query: 462  RTAPLNEDVFTPPAPSPAP-SLDTDIQELSEQIHRLLLQPVHSPSPTGLCGVGAVTSPGP 520
            R +P  ED    P P  +P S   ++  LS       L P    SP       + TSP P
Sbjct: 625  RLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPP 684

Query: 521  ----LHSPGSSSDSNGGDAEGPGPPAPVTFQQICKDVHLVKHQGQQLFIESRARPQSRPR 576
                L  P   S ++    + P  P P       +D  +     +   +     PQ  PR
Sbjct: 685  EASRLSPPPEDSPTSPPPEDSPASPPP-------EDSLMSLPLEESPLLPLPEEPQLCPR 737

Query: 577  LPATGTFKAKALPCQSPDPELEAGSAPVQAP----------LALVPEE---AERKEASSC 623
                        P  SP PE    S   + P          L  VPEE   + + E    
Sbjct: 738  SEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHL 797

Query: 624  SYQQINCLDSILRYLESCNLPSTTKRKCASSSSYTTSSASDDDRQRTGPVSVGTKKDPP- 682
            S Q       +    E  +L    +  C S     +  +   +     P    +   P  
Sbjct: 798  SPQPEEL--HLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPEL 855

Query: 683  -SAALSGEGATPRKEPVVGGTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPESDI 741
                LS     P +EP  G   +P  L      +     + S S  +      +P E  +
Sbjct: 856  EKPPLSPRPEKPPEEP--GQCPAPEELP-----LFPPPGEPSLSPLLGEPALSEPGEPPL 908

Query: 742  IMM-EDLPGLAPGPAPSPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFRD 800
              + E+LP L+P   PS +P   + PDP P    P+ +T A             LS   +
Sbjct: 909  SPLPEELP-LSPSGEPSLSPQ-LMPPDPLPPPLSPI-ITAAA---------PPALSPLGE 956

Query: 801  LGRLRGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEAPCYVSHPS 860
            L    G    S   S L         +PP                     EA C  + P 
Sbjct: 957  LEYPFGAKGDSDPESPLAAPILETPISPPP--------------------EANC--TDPE 994

Query: 861  PVPPSTPWPTP--PATTPFPAVVQPYP---LPVFSPRGGPQPLPPAPTSVP--PAAFPAP 913
            PVPP    P+P  P     P +++P P    P+      PQ  PP+  S P  P + P+P
Sbjct: 995  PVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSP 1054

Query: 914  LVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLPALAPSPPHRPDSPL 973
            L +P+  +V                +   AE           P  PAL PS      SP+
Sbjct: 1055 L-SPIGKVV---------------GVSDEAELHEMETEKVSEPECPALEPSATSPLPSPM 1098

Query: 974  FNSRCSSPLQLNLLQ-----LEELPRAEGAAVAGG-------PGSSAGPPPPSAEAAEPE 1021
             +  C +P     L       E+    +G    G        PGS A     S    +PE
Sbjct: 1099 GDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPE 1158

Query: 1022 ARLAEVT-----ESSNQDALSGS---------------------SDLLELL--LQEDSRS 1053
              LA VT         Q A  GS                     SD++  +  L +   S
Sbjct: 1159 -ELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDAS 1217

Query: 1054 GTGSAASGSLGSGLGSGSGSGSHE-GGSTSASITRSSQSSH--TSKYFGSIDSSEAEAGA 1110
             +   +   LGS    G GS S E G ST  S  R   S    T     + DS   +AG 
Sbjct: 1218 ASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARDEGSLRLCTDSLPETDDSLLCDAGT 1277

Query: 1111 A-RGGAEPGDQ 1120
            A  GG   G++
Sbjct: 1278 AISGGKAEGEK 1288



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 65/253 (25%), Positives = 86/253 (33%), Gaps = 51/253 (20%)

Query: 737  PESDIIMMEDLPGLAPGPAPSPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLS 796
            P  D + + + PG+  G A  P  SP            P G ++  L +  +KEE    S
Sbjct: 2250 PSLDNLAVPESPGVGGGKASEPLLSPP-----------PFGESRKALEV--KKEELGASS 2296

Query: 797  RFRDLGRLRGLDSSSTAPSALGER----GCHHGPAPP-SRRHHCRSKAKRSRHHQNPRAE 851
                   L  +DS S+     G           P  P + +   +S     R  + P A+
Sbjct: 2297 PSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQ 2356

Query: 852  A--PCYVSHPS-----------PVPPSTPWPTPP------ATTPFPAVVQPYPLPVFSPR 892
            A  P   SHP              PP TP P PP      A  P      P+     SP+
Sbjct: 2357 ALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQ 2416

Query: 893  ---GGPQPLPPAPTSVPPAAFPAPLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTP 949
                   PL P P S   A  P+P        V P +  P P S P    Q  +  P  P
Sbjct: 2417 SQSSSQSPLTPRPLSA-EAFCPSP--------VTPRFQSPDPYSRPPSRPQ--SRDPFAP 2465

Query: 950  ASHSPSPSLPALA 962
                P P  P +A
Sbjct: 2466 LHKPPRPQPPEVA 2478



 Score = 35.4 bits (80), Expect = 0.36
 Identities = 29/93 (31%), Positives = 33/93 (35%), Gaps = 9/93 (9%)

Query: 929  PTPSSYPYGALQTPAEGPPTPASHSPSPSLPALAPSPPHRPDSPLFNSRCSSPLQLNLLQ 988
            PT  SY Y            P    PSP    LAPSP   P  PL        ++L    
Sbjct: 4889 PTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPL--------VELPTEP 4940

Query: 989  LEELPRAEGAAVAGGPGSSAGPPPPSAEAAEPE 1021
            L E P      +A  P  SA P P +    E E
Sbjct: 4941 LAEPPVPSPLPLASSP-ESARPKPRARPPEEGE 4972



 Score = 34.7 bits (78), Expect = 0.61
 Identities = 73/301 (24%), Positives = 88/301 (29%), Gaps = 91/301 (30%)

Query: 733  DKKPPESDIIMMEDLPGLAPGPAPSPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQ 792
            +K+    DI    D P L     P P    +  P  AP  +     T A LS        
Sbjct: 2085 NKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSAD---- 2140

Query: 793  AFLSRFRDLGRLRGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEA 852
                     G L+    S   P + GE      P  P++              Q+P   A
Sbjct: 2141 ---------GFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPS-----------QDPFGLA 2180

Query: 853  PCYVSHPSPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPTSVPPAAFPA 912
            P Y   P        +PT P T P      PYP    SP G                  A
Sbjct: 2181 PAYPLEPR-------FPTAPPTYP------PYP----SPTG------------------A 2205

Query: 913  PLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLPALAPSPPHRPDSP 972
            P   PM+                 GA   P  G P    H+  P  P   PS P     P
Sbjct: 2206 PAQPPML-----------------GASSRPGAGQP-GEFHTTPPGTPRHQPSTP----DP 2243

Query: 973  LFNSRCSSPLQLNLLQLEELPRAEGAAVAGGPGSS--AGPPPPSAEAAEPEARLAEVTES 1030
                RC S        L+ L   E   V GG  S     PPP        E +  E+  S
Sbjct: 2244 FLKPRCPS--------LDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGAS 2295

Query: 1031 S 1031
            S
Sbjct: 2296 S 2296



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 28/91 (30%), Positives = 35/91 (38%), Gaps = 16/91 (17%)

Query: 883  PYPLPVFSPRGGPQPLPPAPTSVPPAAFPA-PLVTPMVALVLPNYLFPTPSSYPYGALQT 941
            P   P+     GP+P  P     PP A    P++ P+          PTP   P  + Q 
Sbjct: 4269 PQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPV---------HPTP---PPSSPQE 4316

Query: 942  PAEGPPTPASHSPSPSLPALAPSPPHRPDSP 972
            P      P   SPS  LP  A  PP  P +P
Sbjct: 4317 PKRPSQLP---SPSSQLPTEAQLPPTHPGTP 4344



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 41/161 (25%), Positives = 55/161 (34%), Gaps = 14/161 (8%)

Query: 901  APTSVPPAAFPAPLVTPMVALV--LPNYL-FPTPSSYPYGAL------QTPAEGPPTPAS 951
            A    PP   P    +P+  L+   P    FP P + P   L      Q P   P  P +
Sbjct: 4236 AVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGA 4295

Query: 952  HSPSPSLPALAPSPP-HRPDSPLFNSRCSSPLQLNLLQLEELPRAEGAAVAGGPGSSAGP 1010
             S  P L  + P+PP   P  P   S+  SP      + +  P   G     GP      
Sbjct: 4296 LSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLE--- 4352

Query: 1011 PPPSAEAAEPEARLAEVTESSNQDALSGSSDLLELLLQEDS 1051
             PP    +   A+LA+   S          +L E    E S
Sbjct: 4353 -PPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQS 4392



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 28/99 (28%), Positives = 30/99 (30%), Gaps = 26/99 (26%)

Query: 860  SPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPTSVPPAAFPAPLVTPMV 919
            S  PP  P P P    P PA     PL           LP  P + PP   P PL     
Sbjct: 4907 SAPPPEEPSPPPSPLAPSPASPPTEPLV---------ELPTEPLAEPPVPSPLPL----- 4952

Query: 920  ALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSL 958
                        +S P  A   P   PP     S  P L
Sbjct: 4953 ------------ASSPESARPKPRARPPEEGEDSRPPRL 4979



 Score = 31.6 bits (70), Expect = 5.1
 Identities = 23/58 (39%), Positives = 27/58 (46%), Gaps = 7/58 (12%)

Query: 858  HPSPVPPSTPWPTPPATTPFPAVVQPYP--LPVFSPRGGPQP----LPPAPTSVPPAA 909
            HP+P P S   P  P+  P P+   P    LP   P G P+P    L P P  V PAA
Sbjct: 4306 HPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHP-GTPKPQGPTLEPPPGRVSPAA 4362



 Score = 30.8 bits (68), Expect = 8.8
 Identities = 37/151 (24%), Positives = 53/151 (35%), Gaps = 20/151 (13%)

Query: 473  PPAPS--PAPSLDTDIQELSEQIHRLLLQPV----HSPSPTGLCGVGAVTSPGPLHSPGS 526
            PPA +  P+P    DI             P+      P P   C +   + P    S   
Sbjct: 2353 PPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVP 2412

Query: 527  SSDSNGGDAEGPGPPAPVTFQQICKDVHLVKHQGQQLFIESRARPQSR---------PR- 576
            +S  +   ++ P  P P++ +  C      + Q    +    +RPQSR         PR 
Sbjct: 2413 ASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRP 2472

Query: 577  LPATGTFKAKALPCQSPDPELEAGSAPVQAP 607
             P    FKA +L   S    L AG  P   P
Sbjct: 2473 QPPEVAFKAGSLAHTS----LGAGGFPAALP 2499


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 99/371 (26%), Positives = 127/371 (34%), Gaps = 64/371 (17%)

Query: 736  PPESDIIMMEDLPGLAPGPAPSPAPSPTVAPDPAPD----AYRPVGLTKAVLSLHTQKEE 791
            PP S  + ++ +    P  AP   P  T+ P+        A  P G+  A LS+H+   +
Sbjct: 848  PPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGV--AALSIHSAVAQ 905

Query: 792  QAFLSRFRDLGRLRGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAE 851
                           L      P+A  +        PPS  H            QN RA 
Sbjct: 906  ---------------LPGQPVYPAAFPQMA--PTDVPPSPHHTV----------QNMRAT 938

Query: 852  APCYVSHPSPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQP-LPPAPTSVPPAAF 910
             P     P P  P  P   P  T P   V+ P P     P   PQP LPP P   P  A 
Sbjct: 939  PPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPAL 998

Query: 911  P--------------APLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSP 956
            P              AP  TP   ++L +   P P +    A Q P    P P +   SP
Sbjct: 999  PVRPEPLQPHLPEQAAPAATPGSQILLGH---PAPYAVDVAA-QVPT--VPVPPAAVLSP 1052

Query: 957  SLP-ALAPSPPH-RPDSPLFNSRCSSPLQLNLLQLEELPRAEGAAVAGGPGSSAGPPPPS 1014
             LP  L P+ P   P  P   +  S+ +Q    Q   L       + GGPG  A P P  
Sbjct: 1053 PLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPG-IASPCPTV 1111

Query: 1015 AEAAEPEARLAEVTESSNQDALSGSSDLLELLLQEDSRSG--TGSAASGSLGSGLGSGSG 1072
                EP        E ++QD   G     E     D  SG     +  G+ G G   G  
Sbjct: 1112 QLTVEPVQE-----EQASQDKPPGLPQSCESYGGSDVTSGKELSDSCEGAFGGGRLEGRA 1166

Query: 1073 SGSHEGGSTSA 1083
            +  H   ST A
Sbjct: 1167 ARKHHRRSTRA 1177



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 83/326 (25%), Positives = 113/326 (34%), Gaps = 72/326 (22%)

Query: 685 ALSGEGATPR-KEPVVGGTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPESDIIM 743
           A +G+   P  +EP     L P  L   A S+ S ++  S   + V+   +   +S  +M
Sbjct: 579 AQAGQPGPPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQS--VM 636

Query: 744 MEDLPGLAPGPAPSPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGR 803
           +  L   AP PA     SP V+  P         L +++ SL   ++  A          
Sbjct: 637 LGSLADAAPSPAQCVC-SPPVSEGPV--------LPQSLPSLGAYQQPTA---------- 677

Query: 804 LRGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEAPCYVSHPSPVP 863
             GL   S    A           PPS + H    A  S     P    P       P P
Sbjct: 678 APGLPVGSVPAPA----------CPPSLQQHFPDPAM-SFAPVLPPPSTPMPTGPGQPAP 726

Query: 864 PSTPWPTPPATTPFPAVVQPYPL-----------PVFSPRG--------GPQPLPPAP-- 902
           P    P     TP P V+ P P+           P  +P           P  +P AP  
Sbjct: 727 PGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQ 786

Query: 903 --TSVPPAAFPAPLVTPMVALV-----------LPNYLFP--TPSSYPYGALQTPAEGPP 947
               VPP   P P+V P+  L            LP    P   P  Y   A+  P+   P
Sbjct: 787 PLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAP 846

Query: 948 TPASHSPSPSLPALAPSPPHRPDSPL 973
            P +   SP+LP  A   PH P +PL
Sbjct: 847 LPPA---SPALPLQAVKLPHPPGAPL 869



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 46/145 (31%), Positives = 60/145 (41%), Gaps = 15/145 (10%)

Query: 859 PSPV-----PPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPTSVPPAA--FP 911
           PSP      PP +  P  P + P    +  Y  P  +P G P    PAP   P     FP
Sbjct: 645 PSPAQCVCSPPVSEGPVLPQSLPS---LGAYQQPTAAP-GLPVGSVPAPACPPSLQQHFP 700

Query: 912 APLVTPMVALVLPNYLFPTPSSYPYGALQTP---AEGPPTPASHSPSPSLPALAPSPPHR 968
            P ++    L  P+   PT    P    Q P   A+  P P   +P P +P L P PPH 
Sbjct: 701 DPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVP-LQPVPPHL 759

Query: 969 PDSPLFNSRCSSPLQLNLLQLEELP 993
           P      S+  +P QL  LQ+ + P
Sbjct: 760 PPYLAPASQVGAPAQLKPLQMPQAP 784



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 58/209 (27%), Positives = 71/209 (33%), Gaps = 43/209 (20%)

Query: 848  PRAEAPCYVSHPSPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGP--QPLPPAPTSV 905
            P    P Y S P+ + PS   P PPA+   P      P P  +P   P    +P AP ++
Sbjct: 826  PPVPPPQYFS-PAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATI 884

Query: 906  PPAAFPAPLVT--------------PMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPAS 951
            P  A   P V               P+     P          P+  +Q     PP PA 
Sbjct: 885  PLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPAL 944

Query: 952  HSPSPSL---PALAPSP-----------PHRPDSPLFNSRCSSPLQLNLLQLEELP---- 993
              P P+L   P L P P           P RP  P+   +   P Q  L     LP    
Sbjct: 945  -PPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPE 1003

Query: 994  -----RAEGAAVAGGPGSS--AGPPPPSA 1015
                   E AA A  PGS    G P P A
Sbjct: 1004 PLQPHLPEQAAPAATPGSQILLGHPAPYA 1032



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 83/369 (22%), Positives = 129/369 (34%), Gaps = 92/369 (24%)

Query: 586  KALPCQSPDPELEAGSAPVQAPLAL------VPEEAERKEASSCSYQQINCLDSILRYLE 639
            KA    S D + + GS P  +P  L        EE+ + +A++  YQQ N L +  R+  
Sbjct: 1256 KAEDMLSEDTDADRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQ-NVLHTGKRWFI 1314

Query: 640  SCNLPSTTKRKCASSSSYTTSSASDDDRQRTGPVSVGTKKDPPSAALSGEGATPRKEPVV 699
             C +      +   SS     S+                  PP A+   + + P K+   
Sbjct: 1315 ICPVAEHPAPEAPESSPPLPLSSL-----------------PPEAS---QDSAPYKDQ-- 1352

Query: 700  GGTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPESDII-MMEDLPGLAPGPAPSP 758
                    L++K +     + Q      +   G   PP +    +    P +   P    
Sbjct: 1353 --------LSSKEQPSFLASQQL-----LSQAGPSNPPGAPPAPLAPSSPPVTALPQDGA 1399

Query: 759  APSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLRGLDSSSTAPSALG 818
            AP+ +  P+PA       G       L ++ E    L+   +          +  P  +G
Sbjct: 1400 APATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEA-------PLAVQPLVVG 1452

Query: 819  ERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEAPCYVSHPSPVPPSTPWPTPPATTPFP 878
               C   PAP         +A  +R    PR           P+PP  P P+P + TP P
Sbjct: 1453 LAPCT--PAP---------EAASTRDASAPR----------EPLPPPAPEPSPHSGTPQP 1491

Query: 879  AVVQPYPLPVFSPRGGPQPLPPAPTSVPPAAFPAPLVTPMVALVLPNYLFPTPSSYPYGA 938
            A+ QP PL          P      S+  +  P+P + P V         P P S    A
Sbjct: 1492 ALGQPAPL---------LPAAVGAVSLATSQLPSPPLGPTVP--------PQPPS----A 1530

Query: 939  LQTPAEGPP 947
            L++  EGPP
Sbjct: 1531 LESDGEGPP 1539



 Score = 38.1 bits (87), Expect = 0.055
 Identities = 44/157 (28%), Positives = 52/157 (33%), Gaps = 48/157 (30%)

Query: 859  PSPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPR-----------GGP------------ 895
            PS  P + P P  P++ P  A+ Q    P  S             GGP            
Sbjct: 1373 PSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELET 1432

Query: 896  -QPLPP---APTSVPPAAF------PAPLVTPMVALVLPNYLFPTPSSYPYGALQTPAEG 945
             QPL     AP +V P         PAP          P    P P+  P     +P  G
Sbjct: 1433 SQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEP-----SPHSG 1487

Query: 946  PPTPASHSPSPSLPALA----------PSPPHRPDSP 972
             P PA   P+P LPA            PSPP  P  P
Sbjct: 1488 TPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVP 1524


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 192/814 (23%), Positives = 285/814 (35%), Gaps = 152/814 (18%)

Query: 301  IRGGPDRDPGPRYQPFRLTPYVTKIRVSDGAPAQPCCLLIAERIHSGYEAPRIPPDKRIF 360
            +  G  R P P     + TP    +R+S   P     LL    +  GY     PP     
Sbjct: 1092 VLSGTSRPPTPTLS-LKPTP-PAPVRLSPAPPPGSSSLLKPLTVPPGYT---FPPAAATT 1146

Query: 361  TTRHTPSCLFQDVDERAAPLLGYLPQDLLGAPVLLFLHPEDRPLMLAIHKKILQLAGQPF 420
            T+  T +         A P     PQ L+ +P +    P    + +    ++  LA +P 
Sbjct: 1147 TSTTTATAT-----TTAVPAPTPAPQRLILSPDMQARLPSGEVVSIG---QLASLAQRPV 1198

Query: 421  DHS----PIRFCARNGEYVTMDTSWA-----GFVHPWSRKVAFVL---GRHKVRTAPLNE 468
             ++    P+ F  + G  +T+  +       G   P  R V  ++   G+H + + P + 
Sbjct: 1199 ANAGGSKPLTFQIQ-GNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHV 1257

Query: 469  DVFTPPAPSPAPSLDTDIQELSEQIHRLLLQPVHSPSPTGLCGVGAVTSPGPLHSPGSSS 528
             +    AP+P P   T +  L          P  +P+PTGL          PL       
Sbjct: 1258 ALIQAVAPTPGP---TPVSVLPSST------PSTTPAPTGLSL--------PL------- 1293

Query: 529  DSNGGDAEGPGPPAPVTFQQICKDVHLVKHQGQQ--LFIESRARPQSRPR---LPATGTF 583
                  A    PP  V    + K   +V  Q  +  L       P  RP    LPA    
Sbjct: 1294 ------AANQVPPTMVNNTGVVK---IVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNP 1344

Query: 584  KAKALPCQSPDPELEAGSAPVQAP------LALVPEEAERKEASSCSYQQINCLDSILRY 637
            +    P + P P L    AP+  P      L LV   +    AS+     +  + S L  
Sbjct: 1345 RPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLT-ISSPLHV 1403

Query: 638  LESCNLPSTTKRKCASSSSYTT--SSASDDDRQRTGPVSVGTKKDPPSAA---------- 685
              S   P+++     +SS   +  SS        + P+SV T    P++A          
Sbjct: 1404 PSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPL 1463

Query: 686  -LSGEG------ATPRKEPVVGGTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPE 738
             +S  G       TP   PVV     P +LA    S  S ++     +T   +   + P 
Sbjct: 1464 TVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGAS-PSASALTLGLATAPSLSSSQTPG 1522

Query: 739  SDIIM---MEDLPGL----APGPAPSPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEE 791
              +++      +PGL    AP  +P   P+  +A  P P A  P    +A L        
Sbjct: 1523 HPLLLAPTSSHVPGLNSTVAPACSPVLVPASALA-SPFPSAPNPAP-AQASLLAPASSAS 1580

Query: 792  QAFLSRFRDLGRLRGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAE 851
            QA  +    L  +    ++  APS          PAPP         A       +P A 
Sbjct: 1581 QALAT---PLAPMAAPQTAILAPS----------PAPP--------LAPLPVLAPSPGA- 1618

Query: 852  APCYVSHPSPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGG----PQPLP---PAPTS 904
            AP   S  +PVP   P  T P T+   A   P P PV +P       P P+P   P+P S
Sbjct: 1619 APVLASSQTPVPVMAPSST-PGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPAS 1677

Query: 905  VPPAAFPAPLVTPMVALVLPNYLFPTPSSYPYGALQ------TPAEG-PPTPA---SHSP 954
                A  AP + P +    P+      +  P G         TPA    PTPA   S +P
Sbjct: 1678 TQTLAL-APALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAP 1736

Query: 955  SPSLP-----ALAPSPPHRPDSPLFNSRCSSPLQLNLLQLEELPRAEGAAVAGGPGSSAG 1009
             P L      +LAP+PP  P SP+       P   + L L     +          +   
Sbjct: 1737 GPPLGPTQTLSLAPAPPLAPASPV------GPAPAHTLTLAPASSSASLLAPASVQTLTL 1790

Query: 1010 PPPPSAEAAEPEARLAEVTESSNQDALSGSSDLL 1043
             P P        A+   +  +S Q   S +S L+
Sbjct: 1791 SPAPVPTLGPAAAQTLALAPASTQSPASQASSLV 1824



 Score = 51.6 bits (122), Expect = 5e-06
 Identities = 74/297 (24%), Positives = 103/297 (34%), Gaps = 18/297 (6%)

Query: 681  PPSAALSGEGATPRKEPVVGGTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPESD 740
            PP A L     +P   PV+  + +P+ +   A S    TS  S S          P  + 
Sbjct: 1604 PPLAPLPVLAPSPGAAPVLASSQTPVPVM--APSSTPGTSLASASPVPAPTPVLAPSSTQ 1661

Query: 741  IIMMEDLPGLAPGPAPSPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFRD 800
             +    LP   P P PSPA + T+A  PA             LSL T   +  F ++   
Sbjct: 1662 TM----LPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLS 1717

Query: 801  LGRLRGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSR-HHQNPRAEAPCYVSHP 859
            L     L  +     +L        P PP       S A        +P   AP +    
Sbjct: 1718 LTPASSLVPTPAQTLSLA-------PGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTL 1770

Query: 860  SPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQ-PLPPAPTSVPPAAFPAPLVTPM 918
            +P   S     P +       + P P+P   P       L PA T  P +   + +V+  
Sbjct: 1771 APASSSASLLAPASVQTL--TLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSAS 1828

Query: 919  VALVLP-NYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLPALAPSPPHRPDSPLF 974
             A  LP   +   P S       T   GPP+P S + S   P     PP  P SP +
Sbjct: 1829 GAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGPRPRRQPPPPPRSPFY 1885



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 92/369 (24%), Positives = 122/369 (33%), Gaps = 66/369 (17%)

Query: 803  RLRGLDSSSTAPSALGERGCHH--GPAPPSRRHHCRSKAKRSRHHQNPR-AEAPCYVSHP 859
            RLRG  + +   +       H       P R    R +  R      P  A AP  +   
Sbjct: 2398 RLRGARAETQGANHTPVISAHQTRSTTTPPRCSPARERVPRPAPRPRPTPASAPAAIPAL 2457

Query: 860  SPVPPSTPWP--TPPATTPFPAVVQPYPLPV--FSPRGGPQPLPPAPTSVPPAAFPAP-- 913
             PVP S P P   P   T  P  + P P P     P   P   PP   + PPA  P P  
Sbjct: 2458 VPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQ 2517

Query: 914  --LVTPMVALVLPNYLFPTPSS---YPYG----------ALQTPAEGPPTPASHSPSPSL 958
              LVTP   L+L     P  +S    P G          AL +P        + S + SL
Sbjct: 2518 TCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSL 2577

Query: 959  PALAPS----------PPHRPDSPLFNSRCSSPLQLNLL---QLEELP-RAEGAAVAGGP 1004
              + P           P    +  L  S  S  L+   +   Q +E P  AEG  +   P
Sbjct: 2578 SLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLP 2637

Query: 1005 GSSAGP----------PPPSAEAAEPEARLAEVTESSNQDALSGSSDLLELLLQEDSRSG 1054
                 P           PPSA + EP   L E  E+        S +L E      S   
Sbjct: 2638 EGEELPLCVSESNGLELPPSAASDEP---LQEPLEADRT-----SEELTEAKTPTSSPEK 2689

Query: 1055 TGSAASGSLGSGLGSGSGSGSHEGGSTSASITRSSQSSHTSKYFGSIDSSEAEAGAARGG 1114
                 +  + +   S S + S EG S +    R +          S D      G  R G
Sbjct: 2690 PQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRT----------SADVEIRGQGTGRPG 2739

Query: 1115 AEPGDQVIK 1123
              PG +V++
Sbjct: 2740 QPPGPKVLR 2748



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 78/299 (26%), Positives = 111/299 (37%), Gaps = 47/299 (15%)

Query: 785  LHTQKEEQAFLSRFRDLGRLRGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSRH 844
            L   KEE   L +  + G   G D SS        R      AP         + + +R 
Sbjct: 2346 LDQAKEEVFRLPQEEEEGPGAG-DESSCGTGGGTHRRSKKAKAPERPGTRVSERLRGARA 2404

Query: 845  HQNPRAEAPCYVSHPSPVPPSTPWPTPPAT-TPFPAVVQPYPLPVFSPRGGPQPLPPAPT 903
                    P   +H +    + P  +P     P PA  +P P P  +P   P  +P    
Sbjct: 2405 ETQGANHTPVISAHQTRSTTTPPRCSPARERVPRPAP-RPRPTPASAPAAIPALVP---- 2459

Query: 904  SVPPAAFPAPLVTPMVALVLPNYLFPT---PSSYPYGALQTPAEGPP----TPASHSPSP 956
               P + P P+  P    +LP ++ P+   PS  P     +PA  PP     P +H+P P
Sbjct: 2460 --VPVSAPVPISAPNPITILPVHILPSPPPPSQIP--PCSSPACTPPPACTPPPAHTPPP 2515

Query: 957  SLPALAPSPPHRPDSPLFNSRCSSPLQLNL--LQLEELPRAEGAAVAGGPGSSAGPPPPS 1014
            +   L       P SPL     S P+  ++  L L   P AE  A A             
Sbjct: 2516 AQTCLV-----TPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQA------------- 2557

Query: 1015 AEAAEPEA-RLAEVTESSNQD-ALSGSSDLLELLLQ-----EDSRSGTGSAASGSLGSG 1066
               A PE+  LA V  S     +L    DLL + ++     E + S T SA S +L +G
Sbjct: 2558 --LASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAG 2614



 Score = 39.3 bits (90), Expect = 0.025
 Identities = 48/155 (30%), Positives = 62/155 (40%), Gaps = 28/155 (18%)

Query: 826  PAPPSRRHHCRSKAKRSRHHQNPRAEAPCYVSHPSPVPPSTPWPTPPATTPFPAVVQPYP 885
            P PP R    + K  R      P+ E    V   +P  P  P P           V+P P
Sbjct: 981  PDPPPRPKPVKMKVNRMLQPV-PKQEGRTVVVVNNPRAPLGPVP-----------VRPPP 1028

Query: 886  LPVFSPRGGPQPLPPA-PTSVPPAAFPA-----PLVTPMVALVLPNYLFPTPSSYPYGAL 939
             P  S +  P P+P   P S+  +A PA     P   P   ++LP  L P   S P   L
Sbjct: 1029 GPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPP-LQPNSGSLPQ-VL 1086

Query: 940  QTP------AEGPPTPA-SHSPSPSLPA-LAPSPP 966
             +P         PPTP  S  P+P  P  L+P+PP
Sbjct: 1087 PSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPP 1121



 Score = 38.1 bits (87), Expect = 0.055
 Identities = 166/729 (22%), Positives = 244/729 (33%), Gaps = 162/729 (22%)

Query: 500  PVHSPSPTGLCGVGAVTSP---GPLHSPGSSSDSNGGDAEGPGPPAPVTFQQICKDVHLV 556
            P H+P P   C V   +SP   GP   P S+S +N     G  P A +  Q +     L 
Sbjct: 2509 PAHTPPPAQTCLV-TPSSPLLLGPPSVPISASVTNL--PLGLRPEAELCAQALASPESLE 2565

Query: 557  KHQGQQLFIESRARPQSRPRLPATGTF-----KAKALPCQSPDPELEAGSAP----VQAP 607
                      S +    +  LP          K  +L   +P   LEAGS P     +AP
Sbjct: 2566 LASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAP 2625

Query: 608  -------LALVPE--------------EAERKEASSCSYQQINCLDSILRYLESCNLPST 646
                   L ++PE              E     AS    Q+    D     L     P++
Sbjct: 2626 DSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTS 2685

Query: 647  TKRK-----CASSSSYTTSSASDDDRQRTGPVSVGTKKDPPSAALSGEGATPRKEPVVGG 701
            +  K      A  ++ +TSS++    +   P     ++      + G+G     +P    
Sbjct: 2686 SPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPK 2745

Query: 702  TLSPL-----ALANKAESVVSVTSQCSFSSTIVHVGDKKPPESDIIMMEDLPGLAPGPAP 756
             L  L      +  + E V     Q   +ST+V                  PG++   A 
Sbjct: 2746 VLRKLPGRLVTVVEEKELVRRRRQQRGAASTLV------------------PGVSETSA- 2786

Query: 757  SPAPSPTVAPDPAPDAYRPVG---LTKAVLSLHTQKEEQAFLSRFRDLGRLRGLDSSS-- 811
            SP  SP+V     P++  P+G         SL T  ++     R  +LG   G    +  
Sbjct: 2787 SPG-SPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSPENGD 2845

Query: 812  ------TAPSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEAPCYVSHPSPVPPS 865
                  T P+    RG      PP +    RS A   R       EAP           +
Sbjct: 2846 GALLAITPPAVKRRRG-----RPPKKN---RSPADAGRGVD----EAPSSTLK-GKTNGA 2892

Query: 866  TPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPTSVPPAAFPAPLVTPM------- 918
             P P P        V++P  +P      GPQPL P P        P PL++P+       
Sbjct: 2893 DPVPGPETLIVADPVLEPQLIP------GPQPLGPQPVH-----RPNPLLSPVEKRRRGR 2941

Query: 919  --VALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSL--------------PALA 962
               A  LP  +  T SS   G  ++  + PP P+  +P P L                ++
Sbjct: 2942 PPKARDLP--IPGTISSAGDGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTIS 2999

Query: 963  PSPPHRP-DSPLFNSRCSSPLQLNLLQLEELPRAEGAAVA-----GGPGSSAGPPPPSAE 1016
             SPP R    P  N     P QL +L  +     E   +       G G S G      +
Sbjct: 3000 TSPPKRKRGRPPKNPPSPRPSQLPVLDRDSTSVLESCGLGRRRQPQGQGESEG-SSSDED 3058

Query: 1017 AAEPEARLAEV-TESSNQDALSGSSDLLELLLQED---SRSGTGS--------------- 1057
             + P  RLA +  E+           ++  ++Q+D   + SG G                
Sbjct: 3059 GSRPLTRLARLRLEAEGMRGRKSGGSMVVAVIQDDLDLADSGPGGLELTPPVVSLTPKLR 3118

Query: 1058 ---AASGSLGSGLGS----GSGSGSHEGGSTSASITRSSQSSHTSKYFGSIDSSEAEAGA 1110
                  GSL   L +       +G+  GGS   +     Q        GS++ SEAEA  
Sbjct: 3119 STRLRPGSLVPPLETEKLPRKRAGAPVGGSPGLAKRGRLQPPSPLGPEGSVEESEAEAS- 3177

Query: 1111 ARGGAEPGD 1119
              G  E GD
Sbjct: 3178 --GEEEEGD 3184



 Score = 35.4 bits (80), Expect = 0.36
 Identities = 108/435 (24%), Positives = 149/435 (34%), Gaps = 77/435 (17%)

Query: 571  PQSRPRLPATGTFKAKALPCQSPDPELEAGS------APVQAPL---------ALVPEEA 615
            P S P     GT  A A P  +P P L   S      APV +PL         AL P  A
Sbjct: 1634 PSSTP-----GTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALA 1688

Query: 616  ERKEASSCSYQQINCLDSILRYLESCNLPSTTKRKCASSSSYTTSSASDDDRQRTGPVSV 675
                 SS S        +      +  L  T       + + T S A       T  +S+
Sbjct: 1689 PTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSL 1748

Query: 676  GTKKDPPSAALSGEGATPRKEPVVGGTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKK 735
                 PP A  S  G  P        TL+ LA A+ + S+++  S  + + +   V    
Sbjct: 1749 APA--PPLAPASPVGPAPAH------TLT-LAPASSSASLLAPASVQTLTLSPAPVPTLG 1799

Query: 736  PPESDIIMMEDLPGLAPGPAPSPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFL 795
            P  +  +       LAP    SPA   +     A  A  P+ +T  V  L   K+E   L
Sbjct: 1800 PAAAQTL------ALAPASTQSPASQASSLVVSASGA-APLPVTM-VSRLPVSKDEPDTL 1851

Query: 796  SRFRDLGRLRGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEAPCY 855
            +      R       STA S  G R     P PP    +  S  ++ +  ++ R E    
Sbjct: 1852 TL-----RSGPPSPPSTATSFGGPRPRRQPPPPPRSPFYLDSLEEKRKRQRSERLERIFQ 1906

Query: 856  VS--HPSPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPT--SVPPAAFP 911
            +S  H +  P          T P          PV SP G   P P  PT  +   AA  
Sbjct: 1907 LSEAHGALAPVYGTEVLDFCTLP---------QPVASPIGPRSPGPSHPTFWTYTEAAHR 1957

Query: 912  APLVTPM----VALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLPALAPSPPH 967
            A L        ++ ++  ++F  P          P E PP        PSL A  P P  
Sbjct: 1958 AVLFPQQRLDQLSEIIERFIFVMP----------PVEAPP--------PSLHACHPPPWL 1999

Query: 968  RPDSPLFNSRCSSPL 982
             P    F  + +S L
Sbjct: 2000 APRQAAFQEQLASEL 2014



 Score = 31.6 bits (70), Expect = 5.1
 Identities = 101/451 (22%), Positives = 143/451 (31%), Gaps = 72/451 (15%)

Query: 693  PRKEPVVGGTLSPLALANKAESVVSVTSQCSFSSTIVHVGDKKPPESDIIMMEDL----- 747
            PR  P       P  +     + V +++    +   VH+    PP S I           
Sbjct: 2443 PRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACTPP 2502

Query: 748  PGLAPGPAPSPAPSPTVAPDPA-------PDAYRPVGLTKAVLSLHTQKEEQAFLSRFRD 800
            P   P PA +P P+ T    P+       P       +T   L L  + E  A      +
Sbjct: 2503 PACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASPE 2562

Query: 801  LGRLRGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSK-AKRSRHHQNPRAEAPCYVSHP 859
               L  + SS T+  +L          PP        +    S  + +    AP      
Sbjct: 2563 SLELASVASSETSSLSL---------VPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEA 2613

Query: 860  SPVPPSTPWPTPPAT--TPFPAVVQPYPLPVFSPRGGPQPLPPAPTSVPPAAFPAPLVTP 917
              +P       P +   T    + +   LP+         LPP+  S  P     PL   
Sbjct: 2614 GSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEP--LQEPLEAD 2671

Query: 918  MVALVLPNYLFPTPS-SYPYGALQTPAEGPPTPASHSPSPSLPALAPSPPHRPDSPLFNS 976
              +  L     PT S   P   +      P T +S + SP  P+ A  PP R        
Sbjct: 2672 RTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPA-RPPRR-------- 2722

Query: 977  RCSSPLQLNLLQLEELPRAEGAAVAGGPGSSAGPPPPSAEAAEPEARLAEVTESSNQDAL 1036
            R S+ +++         R +G    G PG    PP P      P  RL  V E       
Sbjct: 2723 RTSADVEI---------RGQG---TGRPGQ---PPGPKVLRKLP-GRLVTVVE------- 2759

Query: 1037 SGSSDLLELLLQEDSRSGT-------GSAASGSLGSGLGSGSGSGSHEGGSTSASITRSS 1089
                +L+    Q+   + T        SA+ GS      SG  S    GG   A+    S
Sbjct: 2760 --EKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPESSPPIGGPCEAA---PS 2814

Query: 1090 QSSHTSKYFGSIDSSEAEAGAARGGA-EPGD 1119
             S  T      I     E G   GG+ E GD
Sbjct: 2815 SSLPTPPQQPFIARRHIELGVTGGGSPENGD 2845


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 59/178 (33%), Positives = 71/178 (39%), Gaps = 33/178 (18%)

Query: 847  NPRAEAPCYVSHPS--PVPPSTPWPTPPAT----------TPFPAVVQPYPLPVFSPRGG 894
            +P    P   S P   P+ P+   P PP            TP P +++  P P   P   
Sbjct: 1407 DPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPT 1466

Query: 895  PQPLPPAPTSVPPAAFPAPLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSP 954
            PQP PP P   P  A P+P   P+VA        PTPSS P      P   PP PA  SP
Sbjct: 1467 PQPQPPPPPPPPQPALPSP--PPLVA--------PTPSSPP----PPPLPPPPPPAMPSP 1512

Query: 955  SPSLP-ALAP--SPPHRPDSPLFNSRCSSPLQLNLLQLEELPRAEGAAVAGGPGSSAG 1009
             P  P A AP  +PP  P +P        P   +   L    + E AAV G     AG
Sbjct: 1513 PPPPPPAAAPLAAPPEEPAAP----SPEDPELPDTRPLHLAKKQETAAVCGETDEEAG 1566



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 39/122 (31%), Positives = 44/122 (36%), Gaps = 22/122 (18%)

Query: 845  HQNPRAEAPCYVSHPSPVPP--STPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAP 902
            + N   E P     P P PP   TP P PP   P P    P P P+ +P     P PP P
Sbjct: 1443 NSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLP 1502

Query: 903  TSVPPAAFPAPLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSP-SPSLPAL 961
               PPA                    P+P   P  A    A  P  PA+ SP  P LP  
Sbjct: 1503 PPPPPA-------------------MPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDT 1543

Query: 962  AP 963
             P
Sbjct: 1544 RP 1545



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 59/231 (25%), Positives = 76/231 (32%), Gaps = 69/231 (29%)

Query: 860  SPVPPSTPWPTPPATTPFPAVVQPY----------PLPVFSPR-------------GGPQ 896
            +P PP  P P PP   P P  ++ +          P P   P              G  +
Sbjct: 832  APQPPPPPPPPPP---PMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALE 888

Query: 897  PLPPAP-------------------TSVPPAAFPAPLVTPMVALVLPNYL--------FP 929
            PLPPAP                    S  P    AP   P+ ++  P+ L        FP
Sbjct: 889  PLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFP 948

Query: 930  TPSSY-------PYGALQTPAEGPPTPASHSPSPSLPALAPSPPHRPDSPLFNSRCSSPL 982
            T            YG    P +     A   P P  PA  P  P+ P         +  L
Sbjct: 949  TMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGL 1008

Query: 983  QLNLLQLEELPRAEGAAVAG----GPGSSAGPPPPS-----AEAAEPEARL 1024
             L+  +  ELP    A   G    GP  +A PPPP      A A+EP+  L
Sbjct: 1009 GLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGL 1059



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 105/456 (23%), Positives = 134/456 (29%), Gaps = 104/456 (22%)

Query: 667  RQRTGPVSVGTKKDPPSAALSGEGATP---------RKEPVVGGT----LSPL------- 706
            R R  P+ V T   P SA+   +GA           RK    GGT    L PL       
Sbjct: 1173 RPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVP 1232

Query: 707  ----ALANKAESVVSVTSQCSFSSTIVH---------VGDKKPPESDIIMMEDLPGLAPG 753
                 L   +   +S T   S  S++           V +K+P      M   L  L  G
Sbjct: 1233 KAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSG 1292

Query: 754  PAPSPAPSPTVAPDPAPDAYRPVGLTKAVLSL---------HTQKEEQAFLSRFRDLGRL 804
                P     + P  +P    P  +    L           H        L    +    
Sbjct: 1293 KRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAES 1352

Query: 805  RGLDSSSTAP-SALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEAPCYVSHPSPV- 862
             GL     +P   L E    +    PS          ++R  Q   + A   +  P    
Sbjct: 1353 EGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAG 1412

Query: 863  PPSTPWPTPPATTPFPAVVQPYPLPVF---SPRGGPQPLPPAPTSVPPAAFPAPLVTPMV 919
            P  T  P  P   P  AV  P PLP     +  G P+P P      PP   PAP   P  
Sbjct: 1413 PKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEP-PLLEEKPPPTPPPAPTPQPQP 1471

Query: 920  ALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLPALAPSPPHRPDSPLFNSRCS 979
                     P P   P  AL +P   PP  A    SP  P L P PP  P  P       
Sbjct: 1472 ---------PPPPPPPQPALPSP---PPLVAPTPSSPPPPPLPPPPP--PAMP------- 1510

Query: 980  SPLQLNLLQLEELPRAEGAAVAGGPGSSAGPPPPSAEAAEP-EARLAEVTESSNQDALSG 1038
                                          PPPP   AA P  A   E    S +D    
Sbjct: 1511 -----------------------------SPPPPPPPAAAPLAAPPEEPAAPSPEDPELP 1541

Query: 1039 SSDLLELLLQEDSRSGTGSAASGSLGSGLGSGSGSG 1074
             +  L L  ++++     +A  G      G   G G
Sbjct: 1542 DTRPLHLAKKQET-----AAVCGETDEEAGESGGEG 1572



 Score = 38.1 bits (87), Expect = 0.055
 Identities = 78/313 (24%), Positives = 107/313 (34%), Gaps = 57/313 (18%)

Query: 753  GPAPSPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFLSRFRDLGRLR----GLD 808
            G A  P  +P       P  Y    + +   SL    +E A  +    LGRL+    G +
Sbjct: 678  GGAGGPPGTPYELAKEDPQRYHLQSVIRTSASL----DEGATAALELGLGRLKEKKKGPE 733

Query: 809  SSSTAPSALGERGCHHG---------------PAPPSRRHHCRSKAKRSRHHQNPRAEAP 853
                 P  L     H+G               P PP+ +       + + H     A  P
Sbjct: 734  RGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQ-----STQPTPHGLLLEAGGP 788

Query: 854  CYVSHPSPVPPSTPWPTP------PATTPFPAVVQPYPLPVFSPRGGPQPLPPAPTSVP- 906
                 P  +PP  P   P      P+ +P  + V  + L   +  G PQP PP P   P 
Sbjct: 789  ---DLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPP 845

Query: 907  -PAAFPAPLVTPMVALVLPN-YLFPTPSSYPYGALQ---------TPAEGPP---TPASH 952
             P    A L +  +    P+  L P  S  P GA+Q          PA G      P S 
Sbjct: 846  MPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSE 905

Query: 953  SPSPSLPALAPSPPHRPDSPLFNSRCSSPLQLNLLQLEE---LPRAEGAAVAGGPGSSAG 1009
               P+    +PS P    +P F    S     +LLQ EE    P  E     GG     G
Sbjct: 906  GKDPAGAYRSPS-PQGTKAPRFVPLTSICFPDSLLQDEERSFFPTME-EMFGGGAADDYG 963

Query: 1010 PPPPSAEAAEPEA 1022
               P  +  +P+A
Sbjct: 964  KAGPPEDEGDPKA 976



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 92/412 (22%), Positives = 127/412 (30%), Gaps = 102/412 (24%)

Query: 724  FSSTIVHVGDKKPPESDIIMMEDLPGLAPGPAPSPAPSPTVAPDPAPDAYRPVGLTKAVL 783
            F + + H G   P  S + ++  L   + GP P P+ S  ++   +P             
Sbjct: 72   FDTGLHHAGSAGPDASVMNLISALE--SRGPQPGPSASSLLSQFRSPSWQT--------- 120

Query: 784  SLHTQKEEQAFLSRFRDLGRLRGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSR 843
            ++HT    + F+S     G L G   SST PS+       H   P S             
Sbjct: 121  AMHTPGPTELFIS-----GALPG---SSTFPSSSALSAYQH---PAS------------- 156

Query: 844  HHQNPRAEAPCYVSHPSPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPT 903
                       + S P PVP S     PP + P   ++ P+ +    P   P        
Sbjct: 157  -----------FGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAP-------- 197

Query: 904  SVPPAAFPAPLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLPALAP 963
                                       PSS  +  L     G   PA   P+ + P   P
Sbjct: 198  -------------------------TVPSSLGFERL--AGGGVLGPAGLGPAQT-PPYRP 229

Query: 964  SPPHRPDSPLFNSRCSSPLQLNLLQLEELPRAEGAAVAGGP------GSSAGPPPPSAEA 1017
             PP  P  P        P Q NLL       A  AA    P      G++ GPPPP  E 
Sbjct: 230  GPPDPPPPPR-----HLPTQFNLLASSS--AAAAAAEQSSPQLYNFSGAAPGPPPP--ER 280

Query: 1018 AEPEARLAEVTESSNQDALSGSSDLLELLLQEDSRSGTGSAASGSLGSGLGSGSGSGSHE 1077
            A P              A           LQ     G    + G   +   S  G G   
Sbjct: 281  ALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPS 340

Query: 1078 GGSTSASITRSSQSSHTSKYFGSIDSSEAEAGAARGGAEPGDQVIKYVLQDP 1129
             G+   S  ++  S  T+   G     EA  G   GG   G    + ++Q P
Sbjct: 341  PGAGEPS--KAGPSGATAGASGRATGPEAAGGGGAGGGGGG---YRPIIQSP 387



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 31/117 (26%), Positives = 44/117 (37%), Gaps = 32/117 (27%)

Query: 656  SYTTSSASDDDRQRTGPVSVGTKKDPPSAALSGEGATPRKEPVVGGTLSPLALANKAESV 715
            S +++ ++ DD    GP    T   PP   L+   A P   P+ G    P A +N     
Sbjct: 1397 SISSAISALDDPPLAGPKDTSTPDGPP---LAPAAAVPGPPPLPG---LPSANSN----- 1445

Query: 716  VSVTSQCSFSSTIVHVGDKKPPESDIIMMEDLPGLAPGPAPSPAPSPTVAPDPAPDA 772
                            G  +PP     ++E+ P   P PAP+P P P   P P   A
Sbjct: 1446 ----------------GTPEPP-----LLEEKPPPTPPPAPTPQPQPPPPPPPPQPA 1481



 Score = 31.2 bits (69), Expect = 6.7
 Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 10/120 (8%)

Query: 654  SSSYTTSSASDDDRQRTGPVSVGTKKDPPSAALSGEGATPRKEPVVGGTLSPLALANKAE 713
            SS    S A + D Q +   ++    DPP A    + +TP   P     L+P A      
Sbjct: 1381 SSDEEDSVAKNRDLQESISSAISALDDPPLAGPK-DTSTPDGPP-----LAPAAAVPGPP 1434

Query: 714  SVVSVTSQCSFSSTIVHVGDKKPPESDIIMMEDLPGLAPGPAPS----PAPSPTVAPDPA 769
             +  + S  S  +    + ++KPP +        P   P P P     P+P P VAP P+
Sbjct: 1435 PLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPS 1494



 Score = 31.2 bits (69), Expect = 6.7
 Identities = 36/156 (23%), Positives = 55/156 (35%), Gaps = 16/156 (10%)

Query: 885  PLPVFSPRGGPQPLPPAPTSVPPAAFPAPLVTPMVALVLPNYLFPTPSSYPYGALQTPAE 944
            P+PV        P+    +S PP   PAP   P           P  ++      QTP  
Sbjct: 1671 PVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPET---------PEKTTSEKPPEQTPET 1721

Query: 945  GPPTPASHSPSPSLPALAPSPPHRPDSPLFNSRCSSPLQLNLLQLEELPRAEGAAVAGGP 1004
              P P    P+P  P+L   P  +       +R   PL+          R E +   G P
Sbjct: 1722 AMPEP----PAPEKPSLL-RPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQP 1776

Query: 1005 GSSAGPP--PPSAEAAEPEARLAEVTESSNQDALSG 1038
             +S  P   P   +A  P  +  +  + +  +A +G
Sbjct: 1777 ATSRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAG 1812


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
            sapiens]
          Length = 1362

 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 58/221 (26%), Positives = 72/221 (32%), Gaps = 24/221 (10%)

Query: 796  SRFRDLGRLRGLDSSSTAPSALGERGCHHGPAPPSRRHHCRSKAKRSRHHQNPRAEAPCY 855
            S+ +         SS ++ S   +      P    + H  R + K   HH     +AP  
Sbjct: 693  SKMKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAP 752

Query: 856  VSHPSPVPPSTPWPTPPATTPFPAVVQPYPLPVFSPRGGPQPLPPAPTSVPPAAFPAPLV 915
            V    P PP  P P PP         Q  P P   P   PQ   PA  S PP     P +
Sbjct: 753  VPQQPPPPPQQPPPPPPPQQ------QQQPPPPPPPPSMPQQAAPAMKSSPP-----PFI 801

Query: 916  TPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPSLPALAPSPPHRPDSPLFN 975
               V ++ P            G++  P      P  H P P LP   P PP     P  N
Sbjct: 802  ATQVPVLEPQL---------PGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLN 852

Query: 976  SRC--SSPLQLNLLQLEELPRAEGAAVAGGPGSSAGPPPPS 1014
                 S P   N   L + P       A  P   A PP  S
Sbjct: 853  QHAVVSPPALHN--ALPQQPSRPSNRAAALPPKPARPPAVS 891



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 40/128 (31%), Positives = 50/128 (39%), Gaps = 26/128 (20%)

Query: 849 RAEAPCYVSHPSPVPP---STPWPTPPAT------TPFPAVVQPYPLPVFSPRGGPQPLP 899
           +A  P     P P PP   +TP P P  T      TP   VV P PL        P P+P
Sbjct: 201 QASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQT------PPPVP 254

Query: 900 PAPTSVPPAAFPAPLVT--PMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPSPS 957
           P P   PPA  P P+ +  P++A        P P     G  +       TP +  P   
Sbjct: 255 PQP-QPPPAPAPQPVQSHPPIIAAT------PQPVKTKKGVKR--KADTTTPTTIDPIHE 305

Query: 958 LPALAPSP 965
            P+L P P
Sbjct: 306 PPSLPPEP 313



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 49/214 (22%), Positives = 66/214 (30%), Gaps = 39/214 (18%)

Query: 826  PAPPSRRHHCRSKAKRSRHHQNPRAEAPCYVSHPSPVPPSTPWPTPPATTPFPAVVQPYP 885
            PAPP      +   ++ +  Q P    P       P PP  P P P          QP P
Sbjct: 919  PAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQ--QPPP 976

Query: 886  LPVFSPRGGPQPL---PPAPTSVPPAAFPAPLVTPMVALVLPNYLFPTPSSYPYGALQTP 942
             P   P+  PQ     PP P  + P  F   +  P           P P        Q P
Sbjct: 977  PPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQP-----------PPPQG------QQP 1019

Query: 943  AEGPPTPASHSPSPSLPALA----PSPPHRPDSPLFNS---RCSSPLQLNLLQLEELPRA 995
               PP      P P+ P        SP H    P          SPL ++  Q+ +    
Sbjct: 1020 PHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSL 1079

Query: 996  EGAAVAGGPGSSAGPPPPSAEAAEPEARLAEVTE 1029
                      +   PP  + +  + E R A V +
Sbjct: 1080 ----------THQSPPQQNVQPKKQELRAASVVQ 1103



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 37/151 (24%), Positives = 54/151 (35%), Gaps = 23/151 (15%)

Query: 473  PPAPSPAPSLDTDIQELSEQIHRLLLQPVHSPSPTGLCGVGAVTSPGPLHSPGSSSDSNG 532
            PP P P P      Q     +H   LQP+   +         +  P P   P      + 
Sbjct: 977  PPPPQPQPPPQQQHQPPPRPVH---LQPMQFSTH--------IQQPPP---PQGQQPPHP 1022

Query: 533  GDAEGPGPPAPVTFQQICKDVHLVKHQGQQLFIESRARPQSRPRL---PATGTFKA---K 586
               + P PP P   QQ+ +  H  +H     +     R    P +   P    F++   +
Sbjct: 1023 PPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQ 1082

Query: 587  ALPCQSPDP---ELEAGSAPVQAPLALVPEE 614
            + P Q+  P   EL A S     PL +V EE
Sbjct: 1083 SPPQQNVQPKKQELRAASVVQPQPLVVVKEE 1113



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 78/338 (23%), Positives = 105/338 (31%), Gaps = 55/338 (16%)

Query: 736  PPESDIIMMEDLPGLAPGPAPSPAPSPTVAPDPAPDAYRPVGLTKAVLSLHTQKEEQAFL 795
            PP    +  +      P P P P P P     P P   RPV L     S H Q+      
Sbjct: 960  PPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPP---RPVHLQPMQFSTHIQQPPPP-- 1014

Query: 796  SRFRDLGRLRGLDSSSTAPSALGERGCHHGPAPPS---RRHHCRSKAKRSRHHQNPRAEA 852
                     +G       P   G++     PA P    + HH     K   +      EA
Sbjct: 1015 ---------QGQQPPHPPP---GQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREA 1062

Query: 853  PCYVSHPSPVP---PSTPWPTPPATTPFP--------AVVQPYPL------PVFSPRGGP 895
            P  +   SP      S    +PP     P        +VVQP PL       + SP    
Sbjct: 1063 PSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRS 1122

Query: 896  QPLPPAPTSVPPAAFPAPLVTPMVALVLPNYLFPTPSSYPYGALQTPAEGPPTPASHSPS 955
            +P  P+    PP   P  +  P   + LP      P       ++ P +  P P   +P 
Sbjct: 1123 EPFSPSLRPEPP-KHPESIKAP---VHLPQRPEMKPVDVGRPVIRPPEQNAPPPG--APD 1176

Query: 956  PSLPALAPSPPHRPDSPLFNSRCSSPLQLNLLQLEELPRAEGAAVAGGPGSSAGPPPPSA 1015
                   P  P  P   L      S   L    +++ P          P S+A     S 
Sbjct: 1177 KDKQKQEPKTPVAPKKDLKIKNMGSWASL----VQKHPTT--------PSSTAKSSSDSF 1224

Query: 1016 EAAEPEARLAEVTESSNQDALSGSSDLLELLLQEDSRS 1053
            E     AR  E  E + +     +    E L QE  RS
Sbjct: 1225 EQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRS 1262


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,553,017
Number of Sequences: 37866
Number of extensions: 4436667
Number of successful extensions: 57420
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 469
Number of HSP's successfully gapped in prelim test: 1814
Number of HSP's that attempted gapping in prelim test: 28035
Number of HSP's gapped (non-prelim): 20642
length of query: 1290
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1176
effective length of database: 13,930,794
effective search space: 16382613744
effective search space used: 16382613744
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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