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Search of human proteins with 190684694
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
(1118 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 2252 0.0
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] 2252 0.0
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens] 2252 0.0
gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens] 271 2e-72
gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo sapi... 271 2e-72
gi|45267835 ubiquitin specific protease 50 [Homo sapiens] 220 7e-57
gi|62243586 ubiquitin-specific protease 21 [Homo sapiens] 212 2e-54
gi|74027267 ubiquitin-specific protease 21 [Homo sapiens] 212 2e-54
gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens] 196 1e-49
gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens] 195 2e-49
gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens] 190 7e-48
gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens] 189 1e-47
gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens] 189 1e-47
gi|57529246 ubiquitin thioesterase 19 [Homo sapiens] 179 1e-44
gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens] 169 1e-41
gi|109638751 ubiquitin specific protease 6 [Homo sapiens] 167 4e-41
gi|22550104 ubiquitin specific protease 32 [Homo sapiens] 166 9e-41
gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens] 157 7e-38
gi|41152235 ubiquitin specific protease 51 [Homo sapiens] 153 1e-36
gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens] 141 3e-33
gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens] 141 3e-33
gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens] 138 3e-32
gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens] 135 3e-31
gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens] 135 3e-31
gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens] 133 8e-31
gi|148612811 ubiquitin specific protease 43 [Homo sapiens] 131 3e-30
gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo sap... 130 7e-30
gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo sapi... 130 7e-30
gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens] 130 7e-30
gi|183396780 ubiquitin specific protease 20 [Homo sapiens] 130 9e-30
>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 2252 bits (5836), Expect = 0.0
Identities = 1118/1118 (100%), Positives = 1118/1118 (100%)
Query: 1 MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAY 60
MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAY
Sbjct: 1 MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAY 60
Query: 61 VLYMKYVTVYNLIKKRPDFKQQQDYFHSILGPGNIKKAVEEAERLSESLKLRYEEAEVRK 120
VLYMKYVTVYNLIKKRPDFKQQQDYFHSILGPGNIKKAVEEAERLSESLKLRYEEAEVRK
Sbjct: 61 VLYMKYVTVYNLIKKRPDFKQQQDYFHSILGPGNIKKAVEEAERLSESLKLRYEEAEVRK 120
Query: 121 KLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSLENVLDSKDKTQKSNGEKNEKCETKEK 180
KLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSLENVLDSKDKTQKSNGEKNEKCETKEK
Sbjct: 121 KLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSLENVLDSKDKTQKSNGEKNEKCETKEK 180
Query: 181 GAITAKELYTMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP 240
GAITAKELYTMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP
Sbjct: 181 GAITAKELYTMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP 240
Query: 241 DDSKDTWKKRGNVEYVVLLDWFSSAKDLQIGTTLRSLKDALFKWESKTVLRNEPLVLEGG 300
DDSKDTWKKRGNVEYVVLLDWFSSAKDLQIGTTLRSLKDALFKWESKTVLRNEPLVLEGG
Sbjct: 241 DDSKDTWKKRGNVEYVVLLDWFSSAKDLQIGTTLRSLKDALFKWESKTVLRNEPLVLEGG 300
Query: 301 YENWLLCYPQYTTNAKVTPPPRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDE 360
YENWLLCYPQYTTNAKVTPPPRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDE
Sbjct: 301 YENWLLCYPQYTTNAKVTPPPRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDE 360
Query: 361 NIELISGQNERMGPLNISTPVEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEE 420
NIELISGQNERMGPLNISTPVEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEE
Sbjct: 361 NIELISGQNERMGPLNISTPVEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEE 420
Query: 421 HRIKSESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEK 480
HRIKSESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEK
Sbjct: 421 HRIKSESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEK 480
Query: 481 ELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKET 540
ELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKET
Sbjct: 481 ELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKET 540
Query: 541 SAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQKKSTGDVPHTSVTGDSGSG 600
SAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQKKSTGDVPHTSVTGDSGSG
Sbjct: 541 SAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQKKSTGDVPHTSVTGDSGSG 600
Query: 601 KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGRIVPGLPSGWAKFLD 660
KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGRIVPGLPSGWAKFLD
Sbjct: 601 KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGRIVPGLPSGWAKFLD 660
Query: 661 PITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSP 720
PITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSP
Sbjct: 661 PITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSP 720
Query: 721 DITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLR 780
DITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLR
Sbjct: 721 DITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLR 780
Query: 781 NLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTG 840
NLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTG
Sbjct: 781 NLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTG 840
Query: 841 QYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDH 900
QYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDH
Sbjct: 841 QYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDH 900
Query: 901 LDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTS 960
LDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTS
Sbjct: 901 LDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTS 960
Query: 961 KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW 1020
KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW
Sbjct: 961 KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW 1020
Query: 1021 KQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRW 1080
KQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRW
Sbjct: 1021 KQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRW 1080
Query: 1081 FKFDDHEVSDISVSSVKSSAAYILFYTSLGPRVTDVAT 1118
FKFDDHEVSDISVSSVKSSAAYILFYTSLGPRVTDVAT
Sbjct: 1081 FKFDDHEVSDISVSSVKSSAAYILFYTSLGPRVTDVAT 1118
>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 2252 bits (5836), Expect = 0.0
Identities = 1118/1118 (100%), Positives = 1118/1118 (100%)
Query: 1 MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAY 60
MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAY
Sbjct: 1 MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAY 60
Query: 61 VLYMKYVTVYNLIKKRPDFKQQQDYFHSILGPGNIKKAVEEAERLSESLKLRYEEAEVRK 120
VLYMKYVTVYNLIKKRPDFKQQQDYFHSILGPGNIKKAVEEAERLSESLKLRYEEAEVRK
Sbjct: 61 VLYMKYVTVYNLIKKRPDFKQQQDYFHSILGPGNIKKAVEEAERLSESLKLRYEEAEVRK 120
Query: 121 KLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSLENVLDSKDKTQKSNGEKNEKCETKEK 180
KLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSLENVLDSKDKTQKSNGEKNEKCETKEK
Sbjct: 121 KLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSLENVLDSKDKTQKSNGEKNEKCETKEK 180
Query: 181 GAITAKELYTMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP 240
GAITAKELYTMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP
Sbjct: 181 GAITAKELYTMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP 240
Query: 241 DDSKDTWKKRGNVEYVVLLDWFSSAKDLQIGTTLRSLKDALFKWESKTVLRNEPLVLEGG 300
DDSKDTWKKRGNVEYVVLLDWFSSAKDLQIGTTLRSLKDALFKWESKTVLRNEPLVLEGG
Sbjct: 241 DDSKDTWKKRGNVEYVVLLDWFSSAKDLQIGTTLRSLKDALFKWESKTVLRNEPLVLEGG 300
Query: 301 YENWLLCYPQYTTNAKVTPPPRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDE 360
YENWLLCYPQYTTNAKVTPPPRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDE
Sbjct: 301 YENWLLCYPQYTTNAKVTPPPRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDE 360
Query: 361 NIELISGQNERMGPLNISTPVEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEE 420
NIELISGQNERMGPLNISTPVEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEE
Sbjct: 361 NIELISGQNERMGPLNISTPVEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEE 420
Query: 421 HRIKSESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEK 480
HRIKSESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEK
Sbjct: 421 HRIKSESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEK 480
Query: 481 ELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKET 540
ELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKET
Sbjct: 481 ELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKET 540
Query: 541 SAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQKKSTGDVPHTSVTGDSGSG 600
SAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQKKSTGDVPHTSVTGDSGSG
Sbjct: 541 SAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQKKSTGDVPHTSVTGDSGSG 600
Query: 601 KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGRIVPGLPSGWAKFLD 660
KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGRIVPGLPSGWAKFLD
Sbjct: 601 KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGRIVPGLPSGWAKFLD 660
Query: 661 PITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSP 720
PITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSP
Sbjct: 661 PITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSP 720
Query: 721 DITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLR 780
DITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLR
Sbjct: 721 DITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLR 780
Query: 781 NLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTG 840
NLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTG
Sbjct: 781 NLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTG 840
Query: 841 QYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDH 900
QYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDH
Sbjct: 841 QYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDH 900
Query: 901 LDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTS 960
LDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTS
Sbjct: 901 LDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTS 960
Query: 961 KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW 1020
KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW
Sbjct: 961 KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW 1020
Query: 1021 KQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRW 1080
KQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRW
Sbjct: 1021 KQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRW 1080
Query: 1081 FKFDDHEVSDISVSSVKSSAAYILFYTSLGPRVTDVAT 1118
FKFDDHEVSDISVSSVKSSAAYILFYTSLGPRVTDVAT
Sbjct: 1081 FKFDDHEVSDISVSSVKSSAAYILFYTSLGPRVTDVAT 1118
>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 2252 bits (5836), Expect = 0.0
Identities = 1118/1118 (100%), Positives = 1118/1118 (100%)
Query: 1 MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAY 60
MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAY
Sbjct: 1 MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAY 60
Query: 61 VLYMKYVTVYNLIKKRPDFKQQQDYFHSILGPGNIKKAVEEAERLSESLKLRYEEAEVRK 120
VLYMKYVTVYNLIKKRPDFKQQQDYFHSILGPGNIKKAVEEAERLSESLKLRYEEAEVRK
Sbjct: 61 VLYMKYVTVYNLIKKRPDFKQQQDYFHSILGPGNIKKAVEEAERLSESLKLRYEEAEVRK 120
Query: 121 KLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSLENVLDSKDKTQKSNGEKNEKCETKEK 180
KLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSLENVLDSKDKTQKSNGEKNEKCETKEK
Sbjct: 121 KLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSLENVLDSKDKTQKSNGEKNEKCETKEK 180
Query: 181 GAITAKELYTMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP 240
GAITAKELYTMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP
Sbjct: 181 GAITAKELYTMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP 240
Query: 241 DDSKDTWKKRGNVEYVVLLDWFSSAKDLQIGTTLRSLKDALFKWESKTVLRNEPLVLEGG 300
DDSKDTWKKRGNVEYVVLLDWFSSAKDLQIGTTLRSLKDALFKWESKTVLRNEPLVLEGG
Sbjct: 241 DDSKDTWKKRGNVEYVVLLDWFSSAKDLQIGTTLRSLKDALFKWESKTVLRNEPLVLEGG 300
Query: 301 YENWLLCYPQYTTNAKVTPPPRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDE 360
YENWLLCYPQYTTNAKVTPPPRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDE
Sbjct: 301 YENWLLCYPQYTTNAKVTPPPRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDE 360
Query: 361 NIELISGQNERMGPLNISTPVEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEE 420
NIELISGQNERMGPLNISTPVEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEE
Sbjct: 361 NIELISGQNERMGPLNISTPVEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEE 420
Query: 421 HRIKSESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEK 480
HRIKSESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEK
Sbjct: 421 HRIKSESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEK 480
Query: 481 ELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKET 540
ELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKET
Sbjct: 481 ELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKET 540
Query: 541 SAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQKKSTGDVPHTSVTGDSGSG 600
SAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQKKSTGDVPHTSVTGDSGSG
Sbjct: 541 SAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQKKSTGDVPHTSVTGDSGSG 600
Query: 601 KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGRIVPGLPSGWAKFLD 660
KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGRIVPGLPSGWAKFLD
Sbjct: 601 KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGRIVPGLPSGWAKFLD 660
Query: 661 PITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSP 720
PITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSP
Sbjct: 661 PITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSP 720
Query: 721 DITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLR 780
DITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLR
Sbjct: 721 DITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLR 780
Query: 781 NLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTG 840
NLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTG
Sbjct: 781 NLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTG 840
Query: 841 QYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDH 900
QYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDH
Sbjct: 841 QYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDH 900
Query: 901 LDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTS 960
LDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTS
Sbjct: 901 LDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTS 960
Query: 961 KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW 1020
KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW
Sbjct: 961 KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW 1020
Query: 1021 KQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRW 1080
KQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRW
Sbjct: 1021 KQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRW 1080
Query: 1081 FKFDDHEVSDISVSSVKSSAAYILFYTSLGPRVTDVAT 1118
FKFDDHEVSDISVSSVKSSAAYILFYTSLGPRVTDVAT
Sbjct: 1081 FKFDDHEVSDISVSSVKSSAAYILFYTSLGPRVTDVAT 1118
>gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens]
Length = 396
Score = 271 bits (694), Expect = 2e-72
Identities = 144/343 (41%), Positives = 200/343 (58%), Gaps = 6/343 (1%)
Query: 772 SGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFG 831
S L GLRNLGNTC+MNSILQCL N L DY + Y D++ + + EEF
Sbjct: 53 SAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGS--NAHTALVEEFA 110
Query: 832 IIMKALWTGQYR-YISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNR 890
+++ +WT +SP +FK I + +F GY+QQD+QE L FL+DGLH ++N+ R
Sbjct: 111 KLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLR 170
Query: 891 KRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFM 950
+ EN DHL D + W+K+ + +S I LF GQ KS++ C C S F+ F
Sbjct: 171 PKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFW 230
Query: 951 YLSLPLASTS--KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLL 1008
LSLP+A + TL DC+RLF+KE+ L + + C CR R+ +KK I + P +L+
Sbjct: 231 DLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILV 290
Query: 1009 VHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHY 1068
+HLKRFS KL T V+FPL +LDL ++ N YNL++VSNH G GGHY
Sbjct: 291 LHLKRFSESRIRTSKLTTFVNFPLRDLDLREFA-SENTNHAVYNLYAVSNHSGTTMGGHY 349
Query: 1069 TAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFYTSLGP 1111
TAYC++ W F+D V+ +S S V++S AY+LFY P
Sbjct: 350 TAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYELASP 392
>gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo sapiens]
Length = 605
Score = 271 bits (694), Expect = 2e-72
Identities = 144/343 (41%), Positives = 200/343 (58%), Gaps = 6/343 (1%)
Query: 772 SGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFG 831
S L GLRNLGNTC+MNSILQCL N L DY + Y D++ + + EEF
Sbjct: 262 SAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGS--NAHTALVEEFA 319
Query: 832 IIMKALWTGQYR-YISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNR 890
+++ +WT +SP +FK I + +F GY+QQD+QE L FL+DGLH ++N+ R
Sbjct: 320 KLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLR 379
Query: 891 KRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFM 950
+ EN DHL D + W+K+ + +S I LF GQ KS++ C C S F+ F
Sbjct: 380 PKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFW 439
Query: 951 YLSLPLASTS--KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLL 1008
LSLP+A + TL DC+RLF+KE+ L + + C CR R+ +KK I + P +L+
Sbjct: 440 DLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILV 499
Query: 1009 VHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHY 1068
+HLKRFS KL T V+FPL +LDL ++ N YNL++VSNH G GGHY
Sbjct: 500 LHLKRFSESRIRTSKLTTFVNFPLRDLDLREFA-SENTNHAVYNLYAVSNHSGTTMGGHY 558
Query: 1069 TAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFYTSLGP 1111
TAYC++ W F+D V+ +S S V++S AY+LFY P
Sbjct: 559 TAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYELASP 601
>gi|45267835 ubiquitin specific protease 50 [Homo sapiens]
Length = 339
Score = 220 bits (560), Expect = 7e-57
Identities = 115/303 (37%), Positives = 168/303 (55%), Gaps = 7/303 (2%)
Query: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835
+TGL NLGNTC +N+I QCLC+ L +YF Y + + L EVA F +M
Sbjct: 43 VTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAFAYLMT 102
Query: 836 ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKE 895
+W G +SP+ F +G + F QQD+QE L+ +++ LHE L K +R
Sbjct: 103 DMWLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALKKYHYSRRRSY 162
Query: 896 ENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLP 955
E + + +K SII LF+ Q ++ CL C K + E F SLP
Sbjct: 163 EKG-------STQRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNEVFTVFSLP 215
Query: 956 LASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFS 1015
+ S +C+L+DCL+ F +++ LT NN +CS C ++++ + I K P +++ HLKRF
Sbjct: 216 IPSKYECSLRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPKIIIFHLKRFD 275
Query: 1016 YDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNA 1075
G K+KL+T + +PL NLDL+ Y+ KYNL +V NH+G LDGGHYTA+CKN+
Sbjct: 276 IQGTTKRKLRTDIHYPLTNLDLTPYICSIFRKYPKYNLCAVVNHFGDLDGGHYTAFCKNS 335
Query: 1076 ARQ 1078
Q
Sbjct: 336 VTQ 338
>gi|62243586 ubiquitin-specific protease 21 [Homo sapiens]
Length = 565
Score = 212 bits (539), Expect = 2e-54
Identities = 125/354 (35%), Positives = 181/354 (51%), Gaps = 26/354 (7%)
Query: 773 GPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGI 832
G GLRNLGNTC++N++LQCL + L D+ R ++ ++ G E+ E F
Sbjct: 208 GSGHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGG---GRAQELTEAFAD 264
Query: 833 IMKALW-TGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRK 891
++ ALW ++P F+ K F+GYSQQD+QE L LM+ LH ++N+ R
Sbjct: 265 VIGALWHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRA 324
Query: 892 RYKEENND---------------HLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQC 936
N L D A W+++ + +S IV LF GQ KS ++C
Sbjct: 325 PPILANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKC 384
Query: 937 LTCHKKSRTFEAFMYLSLPLASTS----KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARR 992
C +S TFE F LSLP+ K +L+DC LF+KEE+L N C CR +
Sbjct: 385 QACGYRSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFNLFTKEEELESENAPVCDRCRQKT 444
Query: 993 DSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLKKYN 1052
S KK+ + + P +L++HL RFS +K VDFPL+ L L + K Y
Sbjct: 445 RSTKKLTVQRFPRILVLHLNRFSASRGSIKKSSVGVDFPLQRLSLGDFA-SDKAGSPVYQ 503
Query: 1053 LFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFY 1106
L+++ NH G + GHYTA C+ + W ++D VS +S + V SS Y+LFY
Sbjct: 504 LYALCNHSGSVHYGHYTALCR--CQTGWHVYNDSRVSPVSENQVASSEGYVLFY 555
>gi|74027267 ubiquitin-specific protease 21 [Homo sapiens]
Length = 565
Score = 212 bits (539), Expect = 2e-54
Identities = 125/354 (35%), Positives = 181/354 (51%), Gaps = 26/354 (7%)
Query: 773 GPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGI 832
G GLRNLGNTC++N++LQCL + L D+ R ++ ++ G E+ E F
Sbjct: 208 GSGHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGG---GRAQELTEAFAD 264
Query: 833 IMKALW-TGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRK 891
++ ALW ++P F+ K F+GYSQQD+QE L LM+ LH ++N+ R
Sbjct: 265 VIGALWHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRA 324
Query: 892 RYKEENND---------------HLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQC 936
N L D A W+++ + +S IV LF GQ KS ++C
Sbjct: 325 PPILANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKC 384
Query: 937 LTCHKKSRTFEAFMYLSLPLASTS----KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARR 992
C +S TFE F LSLP+ K +L+DC LF+KEE+L N C CR +
Sbjct: 385 QACGYRSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFNLFTKEEELESENAPVCDRCRQKT 444
Query: 993 DSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLKKYN 1052
S KK+ + + P +L++HL RFS +K VDFPL+ L L + K Y
Sbjct: 445 RSTKKLTVQRFPRILVLHLNRFSASRGSIKKSSVGVDFPLQRLSLGDFA-SDKAGSPVYQ 503
Query: 1053 LFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFY 1106
L+++ NH G + GHYTA C+ + W ++D VS +S + V SS Y+LFY
Sbjct: 504 LYALCNHSGSVHYGHYTALCR--CQTGWHVYNDSRVSPVSENQVASSEGYVLFY 555
>gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens]
Length = 952
Score = 196 bits (498), Expect = 1e-49
Identities = 100/239 (41%), Positives = 142/239 (59%), Gaps = 4/239 (1%)
Query: 727 QEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLRNLGNTC 786
+ E+ P T N +N C P S + P P L GL NLGNTC
Sbjct: 214 KNEDGTWPRGPSTPNVKNSNYCLP----SYTAYKNYDYSEPGRNNEQPGLCGLSNLGNTC 269
Query: 787 YMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYIS 846
+MNS +QCL N P L +YF + YQ+++N N LG +GE+A+ + ++K +W+G++ Y++
Sbjct: 270 FMNSAIQCLSNTPPLTEYFLNDKYQEELNFDNPLGMRGEIAKSYAELIKQMWSGKFSYVT 329
Query: 847 PKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDFKA 906
P+ FK +G+ QF+GY QQD QELL FL+DGLHEDLN+ + + ++ D D
Sbjct: 330 PRAFKTQVGRFAPQFSGYQQQDCQELLAFLLDGLHEDLNRIRKKPYIQLKDADGRPDKVV 389
Query: 907 AEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQ 965
AE AW+ H + N+SIIV +F G FKST+ C C K S TF+ F YL+LPL + TL+
Sbjct: 390 AEEAWENHLKRNDSIIVDIFHGLFKSTLVCPECAKISVTFDPFCYLTLPLPMKKERTLE 448
Score = 162 bits (411), Expect = 1e-39
Identities = 71/143 (49%), Positives = 100/143 (69%)
Query: 964 LQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQK 1023
L+DC+ LF+ +EKL + +YC +C+ + + KK+++W LPPVL+VHLKRFSY + K
Sbjct: 759 LKDCIELFTTKEKLGAEDPWYCPNCKEHQQATKKLDLWSLPPVLVVHLKRFSYSRYMRDK 818
Query: 1024 LQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKF 1083
L T VDFP+ +LD+S+++I P +YNL +VSNHYGG+ GGHYTA+ KN +W+ F
Sbjct: 819 LDTLVDFPINDLDMSEFLINPNAGPCRYNLIAVSNHYGGMGGGHYTAFAKNKDDGKWYYF 878
Query: 1084 DDHEVSDISVSSVKSSAAYILFY 1106
DD VS S + S AAY+LFY
Sbjct: 879 DDSSVSTASEDQIVSKAAYVLFY 901
>gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens]
Length = 520
Score = 195 bits (496), Expect = 2e-49
Identities = 126/363 (34%), Positives = 181/363 (49%), Gaps = 46/363 (12%)
Query: 777 TGLRNLGNTCYMNSILQCLCNAPHLADYFN--------------RNCYQDDINRSNLLGH 822
TGLRNLGNTC+MN+ILQ L N YF R Y N +
Sbjct: 159 TGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVS- 217
Query: 823 KGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHE 882
+ EEF + ALW G SP+ + KI F GY QQD+ E + +L+D LH
Sbjct: 218 ---LVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHL 274
Query: 883 DLNKADN---RKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTC 939
+L N R +EN+ K + +++ A+F G ++ V CL C
Sbjct: 275 ELQGGFNGVSRSAILQENSTLSASNKCCING-------ASTVVTAIFGGILQNEVNCLIC 327
Query: 940 HKKSRTFEAFMYLSLPLASTSK------------CTLQDCLRLFSKEEKLTDNNRFYCSH 987
+SR F+ F+ LSL + S + C+L+DCLR F+ E+L + + C
Sbjct: 328 GTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHK 387
Query: 988 CRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNN 1047
C+ ++ S KK I KLP VL +HLKRF + + K+ T V+FPL LD+ Y++ P+N+
Sbjct: 388 CKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLLEPENS 447
Query: 1048 LKK---YNLFSVSNHYG-GLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYI 1103
+ Y+L +V H+G G+ GHYTAY + RWF F+D V+ +V + AYI
Sbjct: 448 GPESCLYDLAAVVVHHGSGVGSGHYTAYATHEG--RWFHFNDSTVTLTDEETVVKAKAYI 505
Query: 1104 LFY 1106
LFY
Sbjct: 506 LFY 508
>gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens]
Length = 963
Score = 190 bits (482), Expect = 7e-48
Identities = 93/192 (48%), Positives = 122/192 (63%)
Query: 774 PALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGII 833
P + GL NLGNTC+MNS LQCL N P L +YF NCY +++N N LG KGE+AE + +
Sbjct: 306 PGICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNCYLEELNFRNPLGMKGEIAEAYADL 365
Query: 834 MKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRY 893
+K W+G +R I P FK +G QF GY Q DSQELL FL+DGLHEDLN+ ++
Sbjct: 366 VKQAWSGHHRSIVPHVFKNKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYV 425
Query: 894 KEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLS 953
+ + D + A+ AWQ HK+ N+S+IV F G FKST+ C C S TF+ F YLS
Sbjct: 426 ELCDAAGRPDQEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLS 485
Query: 954 LPLASTSKCTLQ 965
+PL + K L+
Sbjct: 486 VPLPISHKRVLE 497
Score = 146 bits (369), Expect = 9e-35
Identities = 66/147 (44%), Positives = 99/147 (67%), Gaps = 4/147 (2%)
Query: 964 LQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQK 1023
LQ+C+ LF+ E L N +YC C+ + + KK+++W LP +L++HLKRFSY ++K
Sbjct: 781 LQECIELFTTVETLEKENPWYCPSCKQHQLATKKLDLWMLPEILIIHLKRFSYTKFSREK 840
Query: 1024 LQTSVDFPLENLDLSQYVIGPKN----NLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQR 1079
L T V+FP+ +LD S++VI P+N L KY+L +VSNHYGG+ GHYT + N +
Sbjct: 841 LDTLVEFPIRDLDFSEFVIQPQNESNPELYKYDLIAVSNHYGGMRDGHYTTFACNKDSGQ 900
Query: 1080 WFKFDDHEVSDISVSSVKSSAAYILFY 1106
W FDD+ VS ++ + ++S AAY+LFY
Sbjct: 901 WHYFDDNSVSPVNENQIESKAAYVLFY 927
>gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens]
Length = 963
Score = 189 bits (480), Expect = 1e-47
Identities = 90/183 (49%), Positives = 124/183 (67%)
Query: 774 PALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGII 833
P L GL NLGNTC+MNS LQCL N L DYF ++ Y+ +INR N LG KGE+AE + +
Sbjct: 299 PGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAYAEL 358
Query: 834 MKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRY 893
+K +W+G+ +++P+ FK +G+ QF+GY QQDSQELL FL+DGLHEDLN+ +
Sbjct: 359 IKQMWSGRDAHVAPRMFKTQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKKPYL 418
Query: 894 KEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLS 953
+ ++ + D A+ AW+ H+ N+S+IV F G FKST+ C C K S TF+ F YL+
Sbjct: 419 ELKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFCYLT 478
Query: 954 LPL 956
LPL
Sbjct: 479 LPL 481
Score = 145 bits (365), Expect = 3e-34
Identities = 63/143 (44%), Positives = 94/143 (65%)
Query: 964 LQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQK 1023
L+DC+ LF+ E L +++ +YC +C+ + + KK ++W LP +L+VHLKRFSY+ W+ K
Sbjct: 778 LRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNRYWRDK 837
Query: 1024 LQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKF 1083
L T V+FP+ L++S++V Y+L +VSNHYG + GHYTAY KN +W+ F
Sbjct: 838 LDTVVEFPIRGLNMSEFVCNLSARPYVYDLIAVSNHYGAMGVGHYTAYAKNKLNGKWYYF 897
Query: 1084 DDHEVSDISVSSVKSSAAYILFY 1106
DD VS S + + AAY+LFY
Sbjct: 898 DDSNVSLASEDQIVTKAAYVLFY 920
>gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens]
Length = 916
Score = 189 bits (480), Expect = 1e-47
Identities = 90/183 (49%), Positives = 124/183 (67%)
Query: 774 PALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGII 833
P L GL NLGNTC+MNS LQCL N L DYF ++ Y+ +INR N LG KGE+AE + +
Sbjct: 252 PGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAYAEL 311
Query: 834 MKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRY 893
+K +W+G+ +++P+ FK +G+ QF+GY QQDSQELL FL+DGLHEDLN+ +
Sbjct: 312 IKQMWSGRDAHVAPRMFKTQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKKPYL 371
Query: 894 KEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLS 953
+ ++ + D A+ AW+ H+ N+S+IV F G FKST+ C C K S TF+ F YL+
Sbjct: 372 ELKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFCYLT 431
Query: 954 LPL 956
LPL
Sbjct: 432 LPL 434
Score = 145 bits (365), Expect = 3e-34
Identities = 63/143 (44%), Positives = 94/143 (65%)
Query: 964 LQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQK 1023
L+DC+ LF+ E L +++ +YC +C+ + + KK ++W LP +L+VHLKRFSY+ W+ K
Sbjct: 731 LRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNRYWRDK 790
Query: 1024 LQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKF 1083
L T V+FP+ L++S++V Y+L +VSNHYG + GHYTAY KN +W+ F
Sbjct: 791 LDTVVEFPIRGLNMSEFVCNLSARPYVYDLIAVSNHYGAMGVGHYTAYAKNKLNGKWYYF 850
Query: 1084 DDHEVSDISVSSVKSSAAYILFY 1106
DD VS S + + AAY+LFY
Sbjct: 851 DDSNVSLASEDQIVTKAAYVLFY 873
>gi|57529246 ubiquitin thioesterase 19 [Homo sapiens]
Length = 1318
Score = 179 bits (455), Expect = 1e-44
Identities = 108/280 (38%), Positives = 144/280 (51%), Gaps = 13/280 (4%)
Query: 691 STPPTHKAKPQIPAERDREPSKLKRSYSSPDITQAIQEEEKRKPT--VTP---TVNRENK 745
STPP P E R K K S D + R P VTP T K
Sbjct: 406 STPPGGAPHPLTGQEEARAVEKDKSKARSEDT--GLDSVATRTPMEHVTPKPETHLASPK 463
Query: 746 PTCY----PKAEISRLSASQIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHL 801
PTC P + +S S + P TGL NLGNTC+MNS++Q L N L
Sbjct: 464 PTCMVPPMPHSPVSGDSVEEEEEEEKKV--CLPGFTGLVNLGNTCFMNSVIQSLSNTREL 521
Query: 802 ADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQF 861
D+F+ ++ +IN +N LG G +A F ++++ALW G + P K + QF
Sbjct: 522 RDFFHDRSFEAEINYNNPLGTGGRLAIGFAVLLRALWKGTHHAFQPSKLKAIVASKASQF 581
Query: 862 AGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESI 921
GY+Q D+QE + FL+DGLHEDLN+ N+ + ++D D AE AWQ+HK N+S
Sbjct: 582 TGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSDGRPDEVVAEEAWQRHKMRNDSF 641
Query: 922 IVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSK 961
IV LFQGQ+KS + C C K S TF+ F+YL +PL K
Sbjct: 642 IVDLFQGQYKSKLVCPVCAKVSITFDPFLYLPVPLPQKQK 681
Score = 131 bits (330), Expect = 3e-30
Identities = 81/232 (34%), Positives = 123/232 (53%), Gaps = 28/232 (12%)
Query: 887 ADNRKRYKEENND---HLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKS 943
+ NR++ E+ D L D + W+ +++L E ++VA ++C
Sbjct: 996 SSNREQRLEDKGDTPLELGDDCSLALVWRNNERLQEFVLVA------SKELEC--AEDPG 1047
Query: 944 RTFEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKL 1003
EA A TL CL LF++ E L +YC C+ R++ K++ +W+L
Sbjct: 1048 SAGEA--------ARAGHFTLDQCLNLFTRPEVLAPEEAWYCPQCKQHREASKQLLLWRL 1099
Query: 1004 PPVLLVHLKRFSYDG-RWKQKLQTSVDFPLENLDLSQYVIGPK-NNLKKYNLFSVSNHYG 1061
P VL+V LKRFS+ W+ K+ V+FP+ NLDLS++ IG K L Y+L++V NHYG
Sbjct: 1100 PNVLIVQLKRFSFRSFIWRDKINDLVEFPVRNLDLSKFCIGQKEEQLPSYDLYAVINHYG 1159
Query: 1062 GLDGGHYTAYCK---NAARQR----WFKFDDHEVSDISVSSVKSSAAYILFY 1106
G+ GGHYTA + + + QR W FDD V+ + S V + AY+LFY
Sbjct: 1160 GMIGGHYTACARLPNDRSSQRSDVGWRLFDDSTVTTVDESQVVTRYAYVLFY 1211
>gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens]
Length = 525
Score = 169 bits (429), Expect = 1e-41
Identities = 126/421 (29%), Positives = 186/421 (44%), Gaps = 66/421 (15%)
Query: 724 QAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLRNLG 783
+ I +EE+RK V + K E+ L + R + L GL NLG
Sbjct: 125 EIIAKEEQRKAWKMQGVGEKFSTWEPTKRELELLKHNPKRR--KITSNCTIGLRGLINLG 182
Query: 784 NTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYR 843
NTC+MN I+Q L + P L D+F D +R + + E + + ++G
Sbjct: 183 NTCFMNCIVQALTHTPLLRDFF-----LSDRHRCEMQSPSSCLVCEMSSLFQEFYSGHRS 237
Query: 844 YISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDD 903
P + AGY QQD+ E L+ +D LH DN K K N +H +
Sbjct: 238 PHIPYKLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDNGK--KANNPNHCN- 294
Query: 904 FKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSK-- 961
II +F G +S V C CH S T + F +SL L +S
Sbjct: 295 ----------------CIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPF 338
Query: 962 ---------------------CTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEI 1000
TL DCLR F++ E L + + CS C + ++S K++ +
Sbjct: 339 WPLSPGSEGNVVNGESHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTM 398
Query: 1001 WKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPK--------------- 1045
KLP V HLKRF + + ++K+ T V FPLE LD++ ++ K
Sbjct: 399 KKLPIVACFHLKRFEHSAKLRRKITTYVSFPLE-LDMTPFMASSKESRMNGQYQQPTDSL 457
Query: 1046 NNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILF 1105
NN KY+LF+V NH G L+ GHYT++ + + +WFK DD ++ S+ V S Y+LF
Sbjct: 458 NNDNKYSLFAVVNHQGTLESGHYTSFIRQ-HKDQWFKCDDAIITKASIKDVLDSEGYLLF 516
Query: 1106 Y 1106
Y
Sbjct: 517 Y 517
>gi|109638751 ubiquitin specific protease 6 [Homo sapiens]
Length = 1406
Score = 167 bits (424), Expect = 4e-41
Identities = 91/223 (40%), Positives = 133/223 (59%), Gaps = 5/223 (2%)
Query: 744 NKPTCYPKAEISRLSASQI-RNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLA 802
NK +P+ ++S+I R P G+ TGL NLGNTC+MNS +QC+ N L
Sbjct: 502 NKDMSWPEEMSFTANSSKIDRQKVPTEKGA----TGLSNLGNTCFMNSSIQCVSNTQPLT 557
Query: 803 DYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFA 862
YF + ++NR+N +G KG +A+ +G +++ LW+G + ++P + TI K +F
Sbjct: 558 QYFISGRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKSVAPLKLRRTIAKYAPKFD 617
Query: 863 GYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESII 922
G+ QQDSQELL FL+DGLHEDLN+ + + +++D D++ A AW H + N SII
Sbjct: 618 GFQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSDGRPDWEVAAEAWDNHLRRNRSII 677
Query: 923 VALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQ 965
V LF GQ +S V+C TC S F+ F +LSLPL S L+
Sbjct: 678 VDLFHGQLRSQVKCKTCGHISVRFDPFNFLSLPLPMDSYMDLE 720
Score = 70.5 bits (171), Expect = 9e-12
Identities = 32/86 (37%), Positives = 50/86 (58%)
Query: 957 ASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSY 1016
A L CLR F+ EE+L ++ +YCS C+ + KK+++W+LPP L++HLKRF +
Sbjct: 1026 AQAEPINLDSCLRAFTSEEELGESEMYYCSKCKTHCLATKKLDLWRLPPFLIIHLKRFQF 1085
Query: 1017 DGRWKQKLQTSVDFPLENLDLSQYVI 1042
K Q V F E+ D S +++
Sbjct: 1086 VNDQWIKSQKIVRFLRESFDPSAFLV 1111
Score = 53.1 bits (126), Expect = 1e-06
Identities = 23/60 (38%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 1051 YNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFYTSLG 1110
YNL+++S H G L GGHY Y KN +W+ ++D ++ + + +AYILFY G
Sbjct: 1312 YNLYAISCHSGILSGGHYITYAKN-PNCKWYCYNDSSCEELHPDEIDTDSAYILFYEQQG 1370
>gi|22550104 ubiquitin specific protease 32 [Homo sapiens]
Length = 1604
Score = 166 bits (421), Expect = 9e-41
Identities = 90/223 (40%), Positives = 134/223 (60%), Gaps = 5/223 (2%)
Query: 744 NKPTCYPKAEISRLSASQI-RNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLA 802
NK +P+ ++S+I R+ P G+ TGL NLGNTC+MNS +QC+ N L
Sbjct: 704 NKDMSWPEEMSFIANSSKIDRHKVPTEKGA----TGLSNLGNTCFMNSSIQCVSNTQPLT 759
Query: 803 DYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFA 862
YF + ++NR+N +G KG +A+ +G +++ LW+G + ++P + TI K +F
Sbjct: 760 QYFISGRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKNVAPLKLRWTIAKYAPRFN 819
Query: 863 GYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESII 922
G+ QQDSQELL FL+DGLHEDLN+ + + +++D D++ A AW H + N SI+
Sbjct: 820 GFQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSDGRPDWEVAAEAWDNHLRRNRSIV 879
Query: 923 VALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQ 965
V LF GQ +S V+C TC S F+ F +LSLPL S L+
Sbjct: 880 VDLFHGQLRSQVKCKTCGHISVRFDPFNFLSLPLPMDSYMHLE 922
Score = 81.6 bits (200), Expect = 4e-15
Identities = 37/87 (42%), Positives = 56/87 (64%), Gaps = 2/87 (2%)
Query: 957 ASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSY 1016
A L CLR F+ EE+L +N +YCS C+ + KK+++W+LPP+L++HLKRF +
Sbjct: 1228 AQAEPINLDSCLRAFTSEEELGENEMYYCSKCKTHCLATKKLDLWRLPPILIIHLKRFQF 1287
Query: 1017 -DGRWKQKLQTSVDFPLENLDLSQYVI 1042
+GRW K Q V FP E+ D S +++
Sbjct: 1288 VNGRW-IKSQKIVKFPRESFDPSAFLV 1313
Score = 53.1 bits (126), Expect = 1e-06
Identities = 23/60 (38%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 1051 YNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFYTSLG 1110
YNL+++S H G L GGHY Y KN +W+ ++D ++ + + +AYILFY G
Sbjct: 1510 YNLYAISCHSGILGGGHYVTYAKN-PNCKWYCYNDSSCKELHPDEIDTDSAYILFYEQQG 1568
>gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens]
Length = 438
Score = 157 bits (396), Expect = 7e-38
Identities = 111/373 (29%), Positives = 172/373 (46%), Gaps = 73/373 (19%)
Query: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835
L GL NLGNTC+MN I+Q L + P L D+F + ++ ++ L + E + +
Sbjct: 77 LRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELC-----LVCEMSSLFR 131
Query: 836 ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLH-----EDLNKADNR 890
L++G P + AGY QQD+ E L+ +D LH +D+ KA N
Sbjct: 132 ELYSGNPSPHVPYKLLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRHCKGDDVGKAAN- 190
Query: 891 KRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFM 950
N +H + II +F G +S V C CH S T +
Sbjct: 191 ------NPNHCN-----------------CIIDQIFTGGLQSDVTCQACHGVSTTIDPCW 227
Query: 951 YLSLPLASTSKC----------------------TLQDCLRLFSKEEKLTDNNRFYCSHC 988
+SL L + TL DCLR F++ E L + + C C
Sbjct: 228 DISLDLPGSCTSFWPMSPGRESSVNGESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSC 287
Query: 989 RARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPK--- 1045
++ ++S K++ + KLP V H KRF + + ++K+ T + FPLE LD++ ++ K
Sbjct: 288 QSYQESTKQLTMNKLPVVACFHFKRFEHSAKQRRKITTYISFPLE-LDMTPFMASSKESR 346
Query: 1046 ------------NNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISV 1093
NN KY+LF+V NH G L+ GHYT++ ++ + +WFK DD ++ S+
Sbjct: 347 MNGQLQLPTNSGNNENKYSLFAVVNHQGTLESGHYTSFIRH-HKDQWFKCDDAVITKASI 405
Query: 1094 SSVKSSAAYILFY 1106
V S Y+LFY
Sbjct: 406 KDVLDSEGYLLFY 418
>gi|41152235 ubiquitin specific protease 51 [Homo sapiens]
Length = 711
Score = 153 bits (386), Expect = 1e-36
Identities = 106/372 (28%), Positives = 171/372 (45%), Gaps = 63/372 (16%)
Query: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835
L GL NLGNTC+MN I+Q L + P L D+F + ++ + +L + E +
Sbjct: 362 LRGLINLGNTCFMNCIVQALTHIPLLKDFFLSDKHKCIMTSPSLC-----LVCEMSSLFH 416
Query: 836 ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKE 895
A+++G P I + AGY QQD+ E L+ ++D LH
Sbjct: 417 AMYSGSRTPHIPYKLLHLIWIHAEHLAGYRQQDAHEFLIAILDVLHR------------- 463
Query: 896 ENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLP 955
H D + A + II +F G +S V C CH S T + +SL
Sbjct: 464 ----HSKDDSGGQEA--NNPNCCNCIIDQIFTGGLQSDVTCQACHSVSTTIDPCWDISLD 517
Query: 956 LASTSKC-----------------------TLQDCLRLFSKEEKLTDNNRFYCSHCRARR 992
L + +L DCL+ F++ E L + + C+ C++ +
Sbjct: 518 LPGSCATFDSQNPERADSTVSRDDHIPGIPSLTDCLQWFTRPEHLGSSAKIKCNSCQSYQ 577
Query: 993 DSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKN------ 1046
+S K++ + KLP V HLKRF + G+ ++K+ T + FPLE LD++ ++ K
Sbjct: 578 ESTKQLTMKKLPIVACFHLKRFEHVGKQRRKINTFISFPLE-LDMTPFLASTKESRMKEG 636
Query: 1047 --------NLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKS 1098
N KY+LF+V NH+G L+ GHYT++ + + +WF DD ++ ++ +
Sbjct: 637 QPPTDCVPNENKYSLFAVINHHGTLESGHYTSFIRQ-QKDQWFSCDDAIITKATIEDLLY 695
Query: 1099 SAAYILFYTSLG 1110
S Y+LFY G
Sbjct: 696 SEGYLLFYHKQG 707
>gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens]
Length = 712
Score = 141 bits (356), Expect = 3e-33
Identities = 137/504 (27%), Positives = 209/504 (41%), Gaps = 111/504 (22%)
Query: 701 QIPAERDREPSKLKRSYSSPDITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSAS 760
Q+ AE + P + + I+ + P TP ++K + EIS+ +
Sbjct: 200 QVKAELESMPPRKSLRLQGLAQSTIIEIVSVQVPAQTPASPAKDKVLSTSENEISQKVSD 259
Query: 761 QIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCL------------------------- 795
P+ P +TGLRNLGNTCYMNS+LQ L
Sbjct: 260 SSVKRRPIVT---PGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASE 316
Query: 796 ----CNAPHLAD---YFNRNCYQDDI----NRSNLL----------GHKGEVAE------ 828
C P + D Y C + D +R + L G K E+ +
Sbjct: 317 KTRSCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTS 376
Query: 829 -------EFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLH 881
E + + +W+G++ +SP ++ ++ F GY+QQD+QE L L+D +
Sbjct: 377 QYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQ 436
Query: 882 EDLNKADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHK 941
+L E L + LN ++ +F GQ S V CL C
Sbjct: 437 REL----------ETTGTSLPALIPTSQRKLIKQVLN--VVNNIFHGQLLSQVTCLACDN 484
Query: 942 KSRTFEAFMYLSLPLASTSKCTLQDC----------LRLFSKEEKLTDNNRFYCSHCRAR 991
KS T E F LSL +C+ +D L F++ E L + + C C ++
Sbjct: 485 KSNTIEPFWDLSLEFPERYQCSGKDIASQPCLVTEMLAKFTETEAL-EGKIYVCDQCNSK 543
Query: 992 R-----------DSLKKIEIWKLPPVLLVHLKRFSYDGRW-KQKLQTSVDFPLENLDLSQ 1039
R ++ K++ I LP VL +HLKRF + GR ++K+ V F E L++
Sbjct: 544 RRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFE-EILNMEP 602
Query: 1040 YVIGPKNNLKK-------YNLFSVSNHYG-GLDGGHYTAYCKNAARQRWFKFDDHEVSDI 1091
Y + LK Y+L +V H+G G GHYTAYC N+ W +D ++S
Sbjct: 603 YCC--RETLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMC 660
Query: 1092 SVSSVKSSAAYILFYTSLGPRVTD 1115
++ V + AYILFYT RVT+
Sbjct: 661 TMDEVCKAQAYILFYTQ---RVTE 681
>gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens]
Length = 712
Score = 141 bits (356), Expect = 3e-33
Identities = 137/504 (27%), Positives = 209/504 (41%), Gaps = 111/504 (22%)
Query: 701 QIPAERDREPSKLKRSYSSPDITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSAS 760
Q+ AE + P + + I+ + P TP ++K + EIS+ +
Sbjct: 200 QVKAELESMPPRKSLRLQGLAQSTIIEIVSVQVPAQTPASPAKDKVLSTSENEISQKVSD 259
Query: 761 QIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCL------------------------- 795
P+ P +TGLRNLGNTCYMNS+LQ L
Sbjct: 260 SSVKRRPIVT---PGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASE 316
Query: 796 ----CNAPHLAD---YFNRNCYQDDI----NRSNLL----------GHKGEVAE------ 828
C P + D Y C + D +R + L G K E+ +
Sbjct: 317 KTRSCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTS 376
Query: 829 -------EFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLH 881
E + + +W+G++ +SP ++ ++ F GY+QQD+QE L L+D +
Sbjct: 377 QYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQ 436
Query: 882 EDLNKADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHK 941
+L E L + LN ++ +F GQ S V CL C
Sbjct: 437 REL----------ETTGTSLPALIPTSQRKLIKQVLN--VVNNIFHGQLLSQVTCLACDN 484
Query: 942 KSRTFEAFMYLSLPLASTSKCTLQDC----------LRLFSKEEKLTDNNRFYCSHCRAR 991
KS T E F LSL +C+ +D L F++ E L + + C C ++
Sbjct: 485 KSNTIEPFWDLSLEFPERYQCSGKDIASQPCLVTEMLAKFTETEAL-EGKIYVCDQCNSK 543
Query: 992 R-----------DSLKKIEIWKLPPVLLVHLKRFSYDGRW-KQKLQTSVDFPLENLDLSQ 1039
R ++ K++ I LP VL +HLKRF + GR ++K+ V F E L++
Sbjct: 544 RRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFE-EILNMEP 602
Query: 1040 YVIGPKNNLKK-------YNLFSVSNHYG-GLDGGHYTAYCKNAARQRWFKFDDHEVSDI 1091
Y + LK Y+L +V H+G G GHYTAYC N+ W +D ++S
Sbjct: 603 YCC--RETLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMC 660
Query: 1092 SVSSVKSSAAYILFYTSLGPRVTD 1115
++ V + AYILFYT RVT+
Sbjct: 661 TMDEVCKAQAYILFYTQ---RVTE 681
>gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens]
Length = 828
Score = 138 bits (347), Expect = 3e-32
Identities = 81/250 (32%), Positives = 121/250 (48%), Gaps = 48/250 (19%)
Query: 905 KAAEHAWQKHKQLNE---SIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPL----- 956
K A+ A K K+ ++ S+I +F G S+VQCLTC + S T E F LSLP+
Sbjct: 455 KKAQSASPKRKKQHKKYRSVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKED 514
Query: 957 -------------ASTSKC--------------------------TLQDCLRLFSKEEKL 977
C TLQDCL F ++L
Sbjct: 515 LAKLHSSSHPTSIVKAGSCGEAYAPQGWIAFFMEYVKSWFWGPVVTLQDCLAAFFARDEL 574
Query: 978 TDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDL 1037
+N + C C+ R+ +K ++ P +L +HLKRF ++ + K+ T V FPLE LDL
Sbjct: 575 KGDNMYSCEKCKKLRNGVKFCKVQNFPEILCIHLKRFRHELMFSTKISTHVSFPLEGLDL 634
Query: 1038 SQYVI-GPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSV 1096
++ + Y+L SV H+G GHY AYC+N W++FDD V+++S S+V
Sbjct: 635 QPFLAKDSPAQIVTYDLLSVICHHGTASSGHYIAYCRNNLNNLWYEFDDQSVTEVSESTV 694
Query: 1097 KSSAAYILFY 1106
+++ AY+LFY
Sbjct: 695 QNAEAYVLFY 704
Score = 72.4 bits (176), Expect = 2e-12
Identities = 44/112 (39%), Positives = 58/112 (51%), Gaps = 7/112 (6%)
Query: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835
LTGL+N+GNTCYMN+ LQ L N P L +F D K + + + +M
Sbjct: 184 LTGLKNIGNTCYMNAALQALSNCPPLTQFFL------DCGGLARTDKKPAICKSYLKLMT 237
Query: 836 ALW-TGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNK 886
LW + + P I +N F GYSQQD+QE L LMD LHE+L +
Sbjct: 238 ELWHKSRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCLMDLLHEELKE 289
>gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens]
Length = 942
Score = 135 bits (339), Expect = 3e-31
Identities = 81/258 (31%), Positives = 121/258 (46%), Gaps = 56/258 (21%)
Query: 905 KAAEHAWQKHKQLNE---SIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLP------ 955
K A+ A K K+ ++ S+I +F G S+VQCLTC + S T E F LSLP
Sbjct: 455 KKAQSASPKRKKQHKKYRSVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKED 514
Query: 956 ------------LASTSKC----------------------------------TLQDCLR 969
+ C TLQDCL
Sbjct: 515 LAKLHSSSHPTSIVKAGSCGEAYAPQGWIAFFMEYVKRFVVSCVPSWFWGPVVTLQDCLA 574
Query: 970 LFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVD 1029
F ++L +N + C C+ R+ +K ++ P +L +HLKRF ++ + K+ T V
Sbjct: 575 AFFARDELKGDNMYSCEKCKKLRNGVKFCKVQNFPEILCIHLKRFRHELMFSTKISTHVS 634
Query: 1030 FPLENLDLSQYVI-GPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEV 1088
FPLE LDL ++ + Y+L SV H+G GHY AYC+N W++FDD V
Sbjct: 635 FPLEGLDLQPFLAKDSPAQIVTYDLLSVICHHGTASSGHYIAYCRNNLNNLWYEFDDQSV 694
Query: 1089 SDISVSSVKSSAAYILFY 1106
+++S S+V+++ AY+LFY
Sbjct: 695 TEVSESTVQNAEAYVLFY 712
Score = 72.4 bits (176), Expect = 2e-12
Identities = 44/112 (39%), Positives = 58/112 (51%), Gaps = 7/112 (6%)
Query: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835
LTGL+N+GNTCYMN+ LQ L N P L +F D K + + + +M
Sbjct: 184 LTGLKNIGNTCYMNAALQALSNCPPLTQFFL------DCGGLARTDKKPAICKSYLKLMT 237
Query: 836 ALW-TGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNK 886
LW + + P I +N F GYSQQD+QE L LMD LHE+L +
Sbjct: 238 ELWHKSRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCLMDLLHEELKE 289
>gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens]
Length = 911
Score = 135 bits (339), Expect = 3e-31
Identities = 81/258 (31%), Positives = 121/258 (46%), Gaps = 56/258 (21%)
Query: 905 KAAEHAWQKHKQLNE---SIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLP------ 955
K A+ A K K+ ++ S+I +F G S+VQCLTC + S T E F LSLP
Sbjct: 424 KKAQSASPKRKKQHKKYRSVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKED 483
Query: 956 ------------LASTSKC----------------------------------TLQDCLR 969
+ C TLQDCL
Sbjct: 484 LAKLHSSSHPTSIVKAGSCGEAYAPQGWIAFFMEYVKRFVVSCVPSWFWGPVVTLQDCLA 543
Query: 970 LFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVD 1029
F ++L +N + C C+ R+ +K ++ P +L +HLKRF ++ + K+ T V
Sbjct: 544 AFFARDELKGDNMYSCEKCKKLRNGVKFCKVQNFPEILCIHLKRFRHELMFSTKISTHVS 603
Query: 1030 FPLENLDLSQYVI-GPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEV 1088
FPLE LDL ++ + Y+L SV H+G GHY AYC+N W++FDD V
Sbjct: 604 FPLEGLDLQPFLAKDSPAQIVTYDLLSVICHHGTASSGHYIAYCRNNLNNLWYEFDDQSV 663
Query: 1089 SDISVSSVKSSAAYILFY 1106
+++S S+V+++ AY+LFY
Sbjct: 664 TEVSESTVQNAEAYVLFY 681
Score = 72.4 bits (176), Expect = 2e-12
Identities = 44/112 (39%), Positives = 58/112 (51%), Gaps = 7/112 (6%)
Query: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835
LTGL+N+GNTCYMN+ LQ L N P L +F D K + + + +M
Sbjct: 153 LTGLKNIGNTCYMNAALQALSNCPPLTQFFL------DCGGLARTDKKPAICKSYLKLMT 206
Query: 836 ALW-TGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNK 886
LW + + P I +N F GYSQQD+QE L LMD LHE+L +
Sbjct: 207 ELWHKSRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCLMDLLHEELKE 258
>gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens]
Length = 370
Score = 133 bits (335), Expect = 8e-31
Identities = 110/358 (30%), Positives = 162/358 (45%), Gaps = 56/358 (15%)
Query: 778 GLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK-- 835
GL N GNTCY NS+LQ L YF R R +L +K + ++ ++
Sbjct: 40 GLVNFGNTCYCNSVLQAL--------YFCRPF------REKVLAYKSQPRKKESLLTCLA 85
Query: 836 ------ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLM----DGLHEDLN 885
A + I PK F + K N+ F Y QQD+ E L +L+ D L E+
Sbjct: 86 DLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERK 145
Query: 886 KADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRT 945
+ R N D+ ++ + W + +FQG + +CLTC S
Sbjct: 146 QEKQNGRLPNGNIDNENNNSTPDPTW----------VDEIFQGTLTNETRCLTCETISSK 195
Query: 946 FEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPP 1005
E F+ LS+ + + T CLR FS E L ++YC CR+++++ K++++ KLP
Sbjct: 196 DEDFLDLSVDVEQNTSIT--HCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPM 253
Query: 1006 VLLVHLKRFSYDGRWKQ--KLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYG-G 1062
+L +HLKRF Y + + KL V FPLE L L N + Y+L +V H G G
Sbjct: 254 ILALHLKRFKYMDQLHRYTKLSYRVVFPLE-LRLFNTSGDATNPDRMYDLVAVVVHCGSG 312
Query: 1063 LDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVK------------SSAAYILFYTS 1108
+ GHY A K + W FDD V I +++ S + YILFY S
Sbjct: 313 PNRGHYIAIVK--SHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQS 368
>gi|148612811 ubiquitin specific protease 43 [Homo sapiens]
Length = 1123
Score = 131 bits (330), Expect = 3e-30
Identities = 61/168 (36%), Positives = 96/168 (57%), Gaps = 23/168 (13%)
Query: 962 CTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWK 1021
CTL +C + ++KEE+L ++ + C HC+ + + K+ +W LP +L++HLKRF G +
Sbjct: 540 CTLDECFQFYTKEEQLAQDDAWKCPHCQVLQQGMVKLSLWTLPDILIIHLKRFCQVGERR 599
Query: 1022 QKLQTSVDFPLENLDLSQYV----------IGPKNNLKK-------------YNLFSVSN 1058
KL T V FPL L+++ +V +GP + K+ Y+L++V N
Sbjct: 600 NKLSTLVKFPLSGLNMAPHVAQRSTSPEAGLGPWPSWKQPDCLPTSYPLDFLYDLYAVCN 659
Query: 1059 HYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFY 1106
H+G L GGHYTAYC+N+ +W+ +DD V + V + AYILFY
Sbjct: 660 HHGNLQGGHYTAYCRNSLDGQWYSYDDSTVEPLREDEVNTRGAYILFY 707
Score = 112 bits (280), Expect = 2e-24
Identities = 65/189 (34%), Positives = 101/189 (53%), Gaps = 12/189 (6%)
Query: 770 GGSGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEE 829
G P GL+N GNTC+MN+++QCL N LA++ Y+ R+ EV E+
Sbjct: 94 GARPPGAQGLKNHGNTCFMNAVVQCLSNTDLLAEFLALGRYRAAPGRA-------EVTEQ 146
Query: 830 FGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADN 889
+++ALWT +Y +FK + K QF G SQ D+ E LL+L+D +HEDL +
Sbjct: 147 LAALVRALWTREYTPQLSAEFKNAVSKYGSQFQGNSQHDALEFLLWLLDRVHEDL---EG 203
Query: 890 RKRYKEENNDHLDDFKAAEHAWQKHKQ--LNESIIVALFQGQFKSTVQCLTCHKKSRTFE 947
R + K +E+ Q L +S + + FQ Q++S++ C C K+S TF+
Sbjct: 204 SSRGPVSEKLPPEATKTSENCLSPSAQLPLGQSFVQSHFQAQYRSSLTCPHCLKQSNTFD 263
Query: 948 AFMYLSLPL 956
F+ +SLP+
Sbjct: 264 PFLCVSLPI 272
>gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo sapiens]
Length = 359
Score = 130 bits (327), Expect = 7e-30
Identities = 109/354 (30%), Positives = 164/354 (46%), Gaps = 48/354 (13%)
Query: 778 GLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK-- 835
GL N GNTCY NS+LQ L YF R R N+L +K + ++ ++
Sbjct: 29 GLVNFGNTCYCNSVLQAL--------YFCRPF------RENVLAYKAQQKKKENLLTCLA 74
Query: 836 ------ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADN 889
A + I PK F + K ND F Y QQD+ E L +L++ + + L +
Sbjct: 75 DLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQE--- 131
Query: 890 RKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAF 949
++ +E+ N L + E A +L + + +FQG + +CL C S E F
Sbjct: 132 -EKKQEKQNGKLKNGNMNEPAENNKPEL--TWVHEIFQGTLTNETRCLNCETVSSKDEDF 188
Query: 950 MYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLV 1009
+ LS+ + + T CLR FS E L ++YC C +++++ K++ + KLP +L +
Sbjct: 189 LDLSVDVEQNTSIT--HCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILAL 246
Query: 1010 HLKRFSYDGRWKQ--KLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYG-GLDGG 1066
HLKRF Y + + KL V FPLE L L N + Y+L +V H G G + G
Sbjct: 247 HLKRFKYMEQLHRYTKLSYRVVFPLE-LRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRG 305
Query: 1067 HYTAYCKNAARQRWFKFDDHEVSDISVSSVK------------SSAAYILFYTS 1108
HY K + W FDD V I +++ S + YILFY S
Sbjct: 306 HYITIVK--SHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQS 357
>gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo sapiens]
Length = 366
Score = 130 bits (327), Expect = 7e-30
Identities = 109/354 (30%), Positives = 164/354 (46%), Gaps = 48/354 (13%)
Query: 778 GLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK-- 835
GL N GNTCY NS+LQ L YF R R N+L +K + ++ ++
Sbjct: 36 GLVNFGNTCYCNSVLQAL--------YFCRPF------RENVLAYKAQQKKKENLLTCLA 81
Query: 836 ------ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADN 889
A + I PK F + K ND F Y QQD+ E L +L++ + + L +
Sbjct: 82 DLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQE--- 138
Query: 890 RKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAF 949
++ +E+ N L + E A +L + + +FQG + +CL C S E F
Sbjct: 139 -EKKQEKQNGKLKNGNMNEPAENNKPEL--TWVHEIFQGTLTNETRCLNCETVSSKDEDF 195
Query: 950 MYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLV 1009
+ LS+ + + T CLR FS E L ++YC C +++++ K++ + KLP +L +
Sbjct: 196 LDLSVDVEQNTSIT--HCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILAL 253
Query: 1010 HLKRFSYDGRWKQ--KLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYG-GLDGG 1066
HLKRF Y + + KL V FPLE L L N + Y+L +V H G G + G
Sbjct: 254 HLKRFKYMEQLHRYTKLSYRVVFPLE-LRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRG 312
Query: 1067 HYTAYCKNAARQRWFKFDDHEVSDISVSSVK------------SSAAYILFYTS 1108
HY K + W FDD V I +++ S + YILFY S
Sbjct: 313 HYITIVK--SHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQS 364
>gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens]
Length = 1352
Score = 130 bits (327), Expect = 7e-30
Identities = 63/169 (37%), Positives = 95/169 (56%), Gaps = 26/169 (15%)
Query: 962 CTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWK 1021
CTL C +L++KEE+L ++ + C HC+ + + +W LP VL++HLKRF +G +
Sbjct: 596 CTLSQCFQLYTKEERLAPDDAWRCPHCKQLQQGSITLSLWTLPDVLIIHLKRFRQEGDRR 655
Query: 1022 QKLQTSVDFPLENLDLSQYVI------------------------GPKNNLKKYNLFSVS 1057
KLQ V FPL LD++ +V+ P++ + Y+L++V
Sbjct: 656 MKLQNMVKFPLTGLDMTPHVVKRSQSSWSLPSHWSPWRRPYGLGRDPEDYI--YDLYAVC 713
Query: 1058 NHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFY 1106
NH+G + GGHYTAYCKN+ W+ FDD +V +S V + AYILFY
Sbjct: 714 NHHGTMQGGHYTAYCKNSVDGLWYCFDDSDVQQLSEDEVCTQTAYILFY 762
Score = 109 bits (273), Expect = 1e-23
Identities = 66/192 (34%), Positives = 101/192 (52%), Gaps = 13/192 (6%)
Query: 774 PALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQ-------DDINRSNLLGHKG-- 824
P + GLRN GNTC+MN+ LQCL N A+Y Y+ D + G +G
Sbjct: 125 PGVAGLRNHGNTCFMNATLQCLSNTELFAEYLALGQYRAGRPEPSPDPEQPAGRGAQGQG 184
Query: 825 EVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDL 884
EV E+ +++ALWT +Y +DFK + K Q+ G SQ D+QE LL+L+D +HEDL
Sbjct: 185 EVTEQLAHLVRALWTLEYTPQHSRDFKTIVSKNALQYRGNSQHDAQEFLLWLLDRVHEDL 244
Query: 885 NKADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSR 944
N + + D ++ + + + LFQ Q++S++ C C K+S
Sbjct: 245 NHSVKQSGQPPLKPPSETDMMPEGPSF----PVCSTFVQELFQAQYRSSLTCPHCQKQSN 300
Query: 945 TFEAFMYLSLPL 956
TF+ F+ +SLP+
Sbjct: 301 TFDPFLCISLPI 312
>gi|183396780 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 130 bits (326), Expect = 9e-30
Identities = 74/248 (29%), Positives = 117/248 (47%), Gaps = 53/248 (21%)
Query: 912 QKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPL--------------- 956
++ +Q S+I +F G S VQCLTC + S T E F LSLP+
Sbjct: 435 RRKEQRYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPIPGKEDLAKLHSAIYQ 494
Query: 957 ---ASTSKC----------------------------------TLQDCLRLFSKEEKLTD 979
A C TL+DCL F ++L
Sbjct: 495 NVPAKPGACGDSYAAQGWLAFIVEYIRRFVVSCTPSWFWGPVVTLEDCLAAFFAADELKG 554
Query: 980 NNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQ 1039
+N + C C+ R+ +K ++ +LP +L +HLKRF ++ + K+ + V FPLE LDL
Sbjct: 555 DNMYSCERCKKLRNGVKYCKVLRLPEILCIHLKRFRHEVMYSFKINSHVSFPLEGLDLRP 614
Query: 1040 YVIGP-KNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKS 1098
++ + + Y+L SV H+G GHY AYC+N +W++FDD V+++ + V++
Sbjct: 615 FLAKECTSQITTYDLLSVICHHGTAGSGHYIAYCQNVINGQWYEFDDQYVTEVHETVVQN 674
Query: 1099 SAAYILFY 1106
+ Y+LFY
Sbjct: 675 AEGYVLFY 682
Score = 71.6 bits (174), Expect = 4e-12
Identities = 42/112 (37%), Positives = 63/112 (56%), Gaps = 7/112 (6%)
Query: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835
LTG++NLGN+CYMN+ LQ L N P L +F C + R++ K + + + ++
Sbjct: 144 LTGMKNLGNSCYMNAALQALSNCPPLTQFF-LEC--GGLVRTD---KKPALCKSYQKLVS 197
Query: 836 ALW-TGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNK 886
+W + Y+ P I +N F GY+QQD+QE L LMD LHE+L +
Sbjct: 198 EVWHKKRPSYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRCLMDQLHEELKE 249
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,951,611
Number of Sequences: 37866
Number of extensions: 2386952
Number of successful extensions: 54911
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1171
Number of HSP's successfully gapped in prelim test: 1247
Number of HSP's that attempted gapping in prelim test: 14952
Number of HSP's gapped (non-prelim): 19120
length of query: 1118
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1005
effective length of database: 13,968,660
effective search space: 14038503300
effective search space used: 14038503300
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.