BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] (1118 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 2252 0.0 gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] 2252 0.0 gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens] 2252 0.0 gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens] 271 2e-72 gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo sapi... 271 2e-72 gi|45267835 ubiquitin specific protease 50 [Homo sapiens] 220 7e-57 gi|62243586 ubiquitin-specific protease 21 [Homo sapiens] 212 2e-54 gi|74027267 ubiquitin-specific protease 21 [Homo sapiens] 212 2e-54 gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens] 196 1e-49 gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens] 195 2e-49 gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens] 190 7e-48 gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens] 189 1e-47 gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens] 189 1e-47 gi|57529246 ubiquitin thioesterase 19 [Homo sapiens] 179 1e-44 gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens] 169 1e-41 gi|109638751 ubiquitin specific protease 6 [Homo sapiens] 167 4e-41 gi|22550104 ubiquitin specific protease 32 [Homo sapiens] 166 9e-41 gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens] 157 7e-38 gi|41152235 ubiquitin specific protease 51 [Homo sapiens] 153 1e-36 gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens] 141 3e-33 gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens] 141 3e-33 gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens] 138 3e-32 gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens] 135 3e-31 gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens] 135 3e-31 gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens] 133 8e-31 gi|148612811 ubiquitin specific protease 43 [Homo sapiens] 131 3e-30 gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo sap... 130 7e-30 gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo sapi... 130 7e-30 gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens] 130 7e-30 gi|183396780 ubiquitin specific protease 20 [Homo sapiens] 130 9e-30 >gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] Length = 1118 Score = 2252 bits (5836), Expect = 0.0 Identities = 1118/1118 (100%), Positives = 1118/1118 (100%) Query: 1 MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAY 60 MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAY Sbjct: 1 MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAY 60 Query: 61 VLYMKYVTVYNLIKKRPDFKQQQDYFHSILGPGNIKKAVEEAERLSESLKLRYEEAEVRK 120 VLYMKYVTVYNLIKKRPDFKQQQDYFHSILGPGNIKKAVEEAERLSESLKLRYEEAEVRK Sbjct: 61 VLYMKYVTVYNLIKKRPDFKQQQDYFHSILGPGNIKKAVEEAERLSESLKLRYEEAEVRK 120 Query: 121 KLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSLENVLDSKDKTQKSNGEKNEKCETKEK 180 KLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSLENVLDSKDKTQKSNGEKNEKCETKEK Sbjct: 121 KLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSLENVLDSKDKTQKSNGEKNEKCETKEK 180 Query: 181 GAITAKELYTMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP 240 GAITAKELYTMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP Sbjct: 181 GAITAKELYTMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP 240 Query: 241 DDSKDTWKKRGNVEYVVLLDWFSSAKDLQIGTTLRSLKDALFKWESKTVLRNEPLVLEGG 300 DDSKDTWKKRGNVEYVVLLDWFSSAKDLQIGTTLRSLKDALFKWESKTVLRNEPLVLEGG Sbjct: 241 DDSKDTWKKRGNVEYVVLLDWFSSAKDLQIGTTLRSLKDALFKWESKTVLRNEPLVLEGG 300 Query: 301 YENWLLCYPQYTTNAKVTPPPRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDE 360 YENWLLCYPQYTTNAKVTPPPRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDE Sbjct: 301 YENWLLCYPQYTTNAKVTPPPRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDE 360 Query: 361 NIELISGQNERMGPLNISTPVEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEE 420 NIELISGQNERMGPLNISTPVEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEE Sbjct: 361 NIELISGQNERMGPLNISTPVEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEE 420 Query: 421 HRIKSESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEK 480 HRIKSESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEK Sbjct: 421 HRIKSESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEK 480 Query: 481 ELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKET 540 ELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKET Sbjct: 481 ELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKET 540 Query: 541 SAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQKKSTGDVPHTSVTGDSGSG 600 SAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQKKSTGDVPHTSVTGDSGSG Sbjct: 541 SAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQKKSTGDVPHTSVTGDSGSG 600 Query: 601 KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGRIVPGLPSGWAKFLD 660 KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGRIVPGLPSGWAKFLD Sbjct: 601 KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGRIVPGLPSGWAKFLD 660 Query: 661 PITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSP 720 PITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSP Sbjct: 661 PITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSP 720 Query: 721 DITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLR 780 DITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLR Sbjct: 721 DITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLR 780 Query: 781 NLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTG 840 NLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTG Sbjct: 781 NLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTG 840 Query: 841 QYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDH 900 QYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDH Sbjct: 841 QYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDH 900 Query: 901 LDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTS 960 LDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTS Sbjct: 901 LDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTS 960 Query: 961 KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW 1020 KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW Sbjct: 961 KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW 1020 Query: 1021 KQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRW 1080 KQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRW Sbjct: 1021 KQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRW 1080 Query: 1081 FKFDDHEVSDISVSSVKSSAAYILFYTSLGPRVTDVAT 1118 FKFDDHEVSDISVSSVKSSAAYILFYTSLGPRVTDVAT Sbjct: 1081 FKFDDHEVSDISVSSVKSSAAYILFYTSLGPRVTDVAT 1118 >gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] Length = 1118 Score = 2252 bits (5836), Expect = 0.0 Identities = 1118/1118 (100%), Positives = 1118/1118 (100%) Query: 1 MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAY 60 MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAY Sbjct: 1 MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAY 60 Query: 61 VLYMKYVTVYNLIKKRPDFKQQQDYFHSILGPGNIKKAVEEAERLSESLKLRYEEAEVRK 120 VLYMKYVTVYNLIKKRPDFKQQQDYFHSILGPGNIKKAVEEAERLSESLKLRYEEAEVRK Sbjct: 61 VLYMKYVTVYNLIKKRPDFKQQQDYFHSILGPGNIKKAVEEAERLSESLKLRYEEAEVRK 120 Query: 121 KLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSLENVLDSKDKTQKSNGEKNEKCETKEK 180 KLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSLENVLDSKDKTQKSNGEKNEKCETKEK Sbjct: 121 KLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSLENVLDSKDKTQKSNGEKNEKCETKEK 180 Query: 181 GAITAKELYTMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP 240 GAITAKELYTMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP Sbjct: 181 GAITAKELYTMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP 240 Query: 241 DDSKDTWKKRGNVEYVVLLDWFSSAKDLQIGTTLRSLKDALFKWESKTVLRNEPLVLEGG 300 DDSKDTWKKRGNVEYVVLLDWFSSAKDLQIGTTLRSLKDALFKWESKTVLRNEPLVLEGG Sbjct: 241 DDSKDTWKKRGNVEYVVLLDWFSSAKDLQIGTTLRSLKDALFKWESKTVLRNEPLVLEGG 300 Query: 301 YENWLLCYPQYTTNAKVTPPPRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDE 360 YENWLLCYPQYTTNAKVTPPPRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDE Sbjct: 301 YENWLLCYPQYTTNAKVTPPPRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDE 360 Query: 361 NIELISGQNERMGPLNISTPVEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEE 420 NIELISGQNERMGPLNISTPVEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEE Sbjct: 361 NIELISGQNERMGPLNISTPVEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEE 420 Query: 421 HRIKSESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEK 480 HRIKSESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEK Sbjct: 421 HRIKSESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEK 480 Query: 481 ELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKET 540 ELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKET Sbjct: 481 ELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKET 540 Query: 541 SAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQKKSTGDVPHTSVTGDSGSG 600 SAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQKKSTGDVPHTSVTGDSGSG Sbjct: 541 SAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQKKSTGDVPHTSVTGDSGSG 600 Query: 601 KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGRIVPGLPSGWAKFLD 660 KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGRIVPGLPSGWAKFLD Sbjct: 601 KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGRIVPGLPSGWAKFLD 660 Query: 661 PITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSP 720 PITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSP Sbjct: 661 PITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSP 720 Query: 721 DITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLR 780 DITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLR Sbjct: 721 DITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLR 780 Query: 781 NLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTG 840 NLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTG Sbjct: 781 NLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTG 840 Query: 841 QYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDH 900 QYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDH Sbjct: 841 QYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDH 900 Query: 901 LDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTS 960 LDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTS Sbjct: 901 LDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTS 960 Query: 961 KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW 1020 KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW Sbjct: 961 KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW 1020 Query: 1021 KQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRW 1080 KQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRW Sbjct: 1021 KQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRW 1080 Query: 1081 FKFDDHEVSDISVSSVKSSAAYILFYTSLGPRVTDVAT 1118 FKFDDHEVSDISVSSVKSSAAYILFYTSLGPRVTDVAT Sbjct: 1081 FKFDDHEVSDISVSSVKSSAAYILFYTSLGPRVTDVAT 1118 >gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens] Length = 1118 Score = 2252 bits (5836), Expect = 0.0 Identities = 1118/1118 (100%), Positives = 1118/1118 (100%) Query: 1 MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAY 60 MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAY Sbjct: 1 MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAY 60 Query: 61 VLYMKYVTVYNLIKKRPDFKQQQDYFHSILGPGNIKKAVEEAERLSESLKLRYEEAEVRK 120 VLYMKYVTVYNLIKKRPDFKQQQDYFHSILGPGNIKKAVEEAERLSESLKLRYEEAEVRK Sbjct: 61 VLYMKYVTVYNLIKKRPDFKQQQDYFHSILGPGNIKKAVEEAERLSESLKLRYEEAEVRK 120 Query: 121 KLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSLENVLDSKDKTQKSNGEKNEKCETKEK 180 KLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSLENVLDSKDKTQKSNGEKNEKCETKEK Sbjct: 121 KLEEKDRQEEAQRLQQKRQETGREDGGTLAKGSLENVLDSKDKTQKSNGEKNEKCETKEK 180 Query: 181 GAITAKELYTMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP 240 GAITAKELYTMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP Sbjct: 181 GAITAKELYTMMTDKNISLIIMDARRMQDYQDSCILHSLSVPEEAISPGVTASWIEAHLP 240 Query: 241 DDSKDTWKKRGNVEYVVLLDWFSSAKDLQIGTTLRSLKDALFKWESKTVLRNEPLVLEGG 300 DDSKDTWKKRGNVEYVVLLDWFSSAKDLQIGTTLRSLKDALFKWESKTVLRNEPLVLEGG Sbjct: 241 DDSKDTWKKRGNVEYVVLLDWFSSAKDLQIGTTLRSLKDALFKWESKTVLRNEPLVLEGG 300 Query: 301 YENWLLCYPQYTTNAKVTPPPRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDE 360 YENWLLCYPQYTTNAKVTPPPRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDE Sbjct: 301 YENWLLCYPQYTTNAKVTPPPRRQNEEVSISLDFTYPSLEESIPSKPAAQTPPASIEVDE 360 Query: 361 NIELISGQNERMGPLNISTPVEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEE 420 NIELISGQNERMGPLNISTPVEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEE Sbjct: 361 NIELISGQNERMGPLNISTPVEPVAASKSDVSPIIQPVPSIKNVPQIDRTKKPAVKLPEE 420 Query: 421 HRIKSESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEK 480 HRIKSESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEK Sbjct: 421 HRIKSESTNHEQQSPQSGKVIPDRSTKPVVFSPTLMLTDEEKARIHAETALLMEKNKQEK 480 Query: 481 ELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKET 540 ELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKET Sbjct: 481 ELRERQQEEQKEKLRKEEQEQKAKKKQEAEENEITEKQQKAKEEMEKKESEQAKKEDKET 540 Query: 541 SAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQKKSTGDVPHTSVTGDSGSG 600 SAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQKKSTGDVPHTSVTGDSGSG Sbjct: 541 SAKRGKEITGVKRQSKSEHETSDAKKSVEDRGKRCPTPEIQKKSTGDVPHTSVTGDSGSG 600 Query: 601 KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGRIVPGLPSGWAKFLD 660 KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGRIVPGLPSGWAKFLD Sbjct: 601 KPFKIKGQPESGILRTGTFREDTDDTERNKAQREPLTRARSEEMGRIVPGLPSGWAKFLD 660 Query: 661 PITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSP 720 PITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSP Sbjct: 661 PITGTFRYYHSPTNTVHMYPPEMAPSSAPPSTPPTHKAKPQIPAERDREPSKLKRSYSSP 720 Query: 721 DITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLR 780 DITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLR Sbjct: 721 DITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLR 780 Query: 781 NLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTG 840 NLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTG Sbjct: 781 NLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTG 840 Query: 841 QYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDH 900 QYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDH Sbjct: 841 QYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDH 900 Query: 901 LDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTS 960 LDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTS Sbjct: 901 LDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTS 960 Query: 961 KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW 1020 KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW Sbjct: 961 KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRW 1020 Query: 1021 KQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRW 1080 KQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRW Sbjct: 1021 KQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRW 1080 Query: 1081 FKFDDHEVSDISVSSVKSSAAYILFYTSLGPRVTDVAT 1118 FKFDDHEVSDISVSSVKSSAAYILFYTSLGPRVTDVAT Sbjct: 1081 FKFDDHEVSDISVSSVKSSAAYILFYTSLGPRVTDVAT 1118 >gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens] Length = 396 Score = 271 bits (694), Expect = 2e-72 Identities = 144/343 (41%), Positives = 200/343 (58%), Gaps = 6/343 (1%) Query: 772 SGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFG 831 S L GLRNLGNTC+MNSILQCL N L DY + Y D++ + + EEF Sbjct: 53 SAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGS--NAHTALVEEFA 110 Query: 832 IIMKALWTGQYR-YISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNR 890 +++ +WT +SP +FK I + +F GY+QQD+QE L FL+DGLH ++N+ R Sbjct: 111 KLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLR 170 Query: 891 KRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFM 950 + EN DHL D + W+K+ + +S I LF GQ KS++ C C S F+ F Sbjct: 171 PKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFW 230 Query: 951 YLSLPLASTS--KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLL 1008 LSLP+A + TL DC+RLF+KE+ L + + C CR R+ +KK I + P +L+ Sbjct: 231 DLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILV 290 Query: 1009 VHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHY 1068 +HLKRFS KL T V+FPL +LDL ++ N YNL++VSNH G GGHY Sbjct: 291 LHLKRFSESRIRTSKLTTFVNFPLRDLDLREFA-SENTNHAVYNLYAVSNHSGTTMGGHY 349 Query: 1069 TAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFYTSLGP 1111 TAYC++ W F+D V+ +S S V++S AY+LFY P Sbjct: 350 TAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYELASP 392 >gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo sapiens] Length = 605 Score = 271 bits (694), Expect = 2e-72 Identities = 144/343 (41%), Positives = 200/343 (58%), Gaps = 6/343 (1%) Query: 772 SGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFG 831 S L GLRNLGNTC+MNSILQCL N L DY + Y D++ + + EEF Sbjct: 262 SAQGLAGLRNLGNTCFMNSILQCLSNTRELRDYCLQRLYMRDLHHGS--NAHTALVEEFA 319 Query: 832 IIMKALWTGQYR-YISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNR 890 +++ +WT +SP +FK I + +F GY+QQD+QE L FL+DGLH ++N+ R Sbjct: 320 KLIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLR 379 Query: 891 KRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFM 950 + EN DHL D + W+K+ + +S I LF GQ KS++ C C S F+ F Sbjct: 380 PKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTDCGYCSTVFDPFW 439 Query: 951 YLSLPLASTS--KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLL 1008 LSLP+A + TL DC+RLF+KE+ L + + C CR R+ +KK I + P +L+ Sbjct: 440 DLSLPIAKRGYPEVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKRCIKKFSIQRFPKILV 499 Query: 1009 VHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHY 1068 +HLKRFS KL T V+FPL +LDL ++ N YNL++VSNH G GGHY Sbjct: 500 LHLKRFSESRIRTSKLTTFVNFPLRDLDLREFA-SENTNHAVYNLYAVSNHSGTTMGGHY 558 Query: 1069 TAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFYTSLGP 1111 TAYC++ W F+D V+ +S S V++S AY+LFY P Sbjct: 559 TAYCRSPGTGEWHTFNDSSVTPMSSSQVRTSDAYLLFYELASP 601 >gi|45267835 ubiquitin specific protease 50 [Homo sapiens] Length = 339 Score = 220 bits (560), Expect = 7e-57 Identities = 115/303 (37%), Positives = 168/303 (55%), Gaps = 7/303 (2%) Query: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835 +TGL NLGNTC +N+I QCLC+ L +YF Y + + L EVA F +M Sbjct: 43 VTGLWNLGNTCCVNAISQCLCSILPLVEYFLTGKYITALQKFLLPSDCSEVATAFAYLMT 102 Query: 836 ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKE 895 +W G +SP+ F +G + F QQD+QE L+ +++ LHE L K +R Sbjct: 103 DMWLGDSDCVSPEIFWSALGNLYPAFTKKMQQDAQEFLICVLNELHEALKKYHYSRRRSY 162 Query: 896 ENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLP 955 E + + +K SII LF+ Q ++ CL C K + E F SLP Sbjct: 163 EKG-------STQRCCRKWITTETSIITQLFEEQLNYSIVCLKCEKCTYKNEVFTVFSLP 215 Query: 956 LASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFS 1015 + S +C+L+DCL+ F +++ LT NN +CS C ++++ + I K P +++ HLKRF Sbjct: 216 IPSKYECSLRDCLQCFFQQDALTWNNEIHCSFCETKQETAVRASISKAPKIIIFHLKRFD 275 Query: 1016 YDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNA 1075 G K+KL+T + +PL NLDL+ Y+ KYNL +V NH+G LDGGHYTA+CKN+ Sbjct: 276 IQGTTKRKLRTDIHYPLTNLDLTPYICSIFRKYPKYNLCAVVNHFGDLDGGHYTAFCKNS 335 Query: 1076 ARQ 1078 Q Sbjct: 336 VTQ 338 >gi|62243586 ubiquitin-specific protease 21 [Homo sapiens] Length = 565 Score = 212 bits (539), Expect = 2e-54 Identities = 125/354 (35%), Positives = 181/354 (51%), Gaps = 26/354 (7%) Query: 773 GPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGI 832 G GLRNLGNTC++N++LQCL + L D+ R ++ ++ G E+ E F Sbjct: 208 GSGHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGG---GRAQELTEAFAD 264 Query: 833 IMKALW-TGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRK 891 ++ ALW ++P F+ K F+GYSQQD+QE L LM+ LH ++N+ R Sbjct: 265 VIGALWHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRA 324 Query: 892 RYKEENND---------------HLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQC 936 N L D A W+++ + +S IV LF GQ KS ++C Sbjct: 325 PPILANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKC 384 Query: 937 LTCHKKSRTFEAFMYLSLPLASTS----KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARR 992 C +S TFE F LSLP+ K +L+DC LF+KEE+L N C CR + Sbjct: 385 QACGYRSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFNLFTKEEELESENAPVCDRCRQKT 444 Query: 993 DSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLKKYN 1052 S KK+ + + P +L++HL RFS +K VDFPL+ L L + K Y Sbjct: 445 RSTKKLTVQRFPRILVLHLNRFSASRGSIKKSSVGVDFPLQRLSLGDFA-SDKAGSPVYQ 503 Query: 1053 LFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFY 1106 L+++ NH G + GHYTA C+ + W ++D VS +S + V SS Y+LFY Sbjct: 504 LYALCNHSGSVHYGHYTALCR--CQTGWHVYNDSRVSPVSENQVASSEGYVLFY 555 >gi|74027267 ubiquitin-specific protease 21 [Homo sapiens] Length = 565 Score = 212 bits (539), Expect = 2e-54 Identities = 125/354 (35%), Positives = 181/354 (51%), Gaps = 26/354 (7%) Query: 773 GPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGI 832 G GLRNLGNTC++N++LQCL + L D+ R ++ ++ G E+ E F Sbjct: 208 GSGHVGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRRDFRQEVPGG---GRAQELTEAFAD 264 Query: 833 IMKALW-TGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRK 891 ++ ALW ++P F+ K F+GYSQQD+QE L LM+ LH ++N+ R Sbjct: 265 VIGALWHPDSCEAVNPTRFRAVFQKYVPSFSGYSQQDAQEFLKLLMERLHLEINRRGRRA 324 Query: 892 RYKEENND---------------HLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQC 936 N L D A W+++ + +S IV LF GQ KS ++C Sbjct: 325 PPILANGPVPSPPRRGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKC 384 Query: 937 LTCHKKSRTFEAFMYLSLPLASTS----KCTLQDCLRLFSKEEKLTDNNRFYCSHCRARR 992 C +S TFE F LSLP+ K +L+DC LF+KEE+L N C CR + Sbjct: 385 QACGYRSTTFEVFCDLSLPIPKKGFAGGKVSLRDCFNLFTKEEELESENAPVCDRCRQKT 444 Query: 993 DSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLKKYN 1052 S KK+ + + P +L++HL RFS +K VDFPL+ L L + K Y Sbjct: 445 RSTKKLTVQRFPRILVLHLNRFSASRGSIKKSSVGVDFPLQRLSLGDFA-SDKAGSPVYQ 503 Query: 1053 LFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFY 1106 L+++ NH G + GHYTA C+ + W ++D VS +S + V SS Y+LFY Sbjct: 504 LYALCNHSGSVHYGHYTALCR--CQTGWHVYNDSRVSPVSENQVASSEGYVLFY 555 >gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens] Length = 952 Score = 196 bits (498), Expect = 1e-49 Identities = 100/239 (41%), Positives = 142/239 (59%), Gaps = 4/239 (1%) Query: 727 QEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLRNLGNTC 786 + E+ P T N +N C P S + P P L GL NLGNTC Sbjct: 214 KNEDGTWPRGPSTPNVKNSNYCLP----SYTAYKNYDYSEPGRNNEQPGLCGLSNLGNTC 269 Query: 787 YMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYIS 846 +MNS +QCL N P L +YF + YQ+++N N LG +GE+A+ + ++K +W+G++ Y++ Sbjct: 270 FMNSAIQCLSNTPPLTEYFLNDKYQEELNFDNPLGMRGEIAKSYAELIKQMWSGKFSYVT 329 Query: 847 PKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDFKA 906 P+ FK +G+ QF+GY QQD QELL FL+DGLHEDLN+ + + ++ D D Sbjct: 330 PRAFKTQVGRFAPQFSGYQQQDCQELLAFLLDGLHEDLNRIRKKPYIQLKDADGRPDKVV 389 Query: 907 AEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQ 965 AE AW+ H + N+SIIV +F G FKST+ C C K S TF+ F YL+LPL + TL+ Sbjct: 390 AEEAWENHLKRNDSIIVDIFHGLFKSTLVCPECAKISVTFDPFCYLTLPLPMKKERTLE 448 Score = 162 bits (411), Expect = 1e-39 Identities = 71/143 (49%), Positives = 100/143 (69%) Query: 964 LQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQK 1023 L+DC+ LF+ +EKL + +YC +C+ + + KK+++W LPPVL+VHLKRFSY + K Sbjct: 759 LKDCIELFTTKEKLGAEDPWYCPNCKEHQQATKKLDLWSLPPVLVVHLKRFSYSRYMRDK 818 Query: 1024 LQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKF 1083 L T VDFP+ +LD+S+++I P +YNL +VSNHYGG+ GGHYTA+ KN +W+ F Sbjct: 819 LDTLVDFPINDLDMSEFLINPNAGPCRYNLIAVSNHYGGMGGGHYTAFAKNKDDGKWYYF 878 Query: 1084 DDHEVSDISVSSVKSSAAYILFY 1106 DD VS S + S AAY+LFY Sbjct: 879 DDSSVSTASEDQIVSKAAYVLFY 901 >gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens] Length = 520 Score = 195 bits (496), Expect = 2e-49 Identities = 126/363 (34%), Positives = 181/363 (49%), Gaps = 46/363 (12%) Query: 777 TGLRNLGNTCYMNSILQCLCNAPHLADYFN--------------RNCYQDDINRSNLLGH 822 TGLRNLGNTC+MN+ILQ L N YF R Y N + Sbjct: 159 TGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVS- 217 Query: 823 KGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHE 882 + EEF + ALW G SP+ + KI F GY QQD+ E + +L+D LH Sbjct: 218 ---LVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLDHLHL 274 Query: 883 DLNKADN---RKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTC 939 +L N R +EN+ K + +++ A+F G ++ V CL C Sbjct: 275 ELQGGFNGVSRSAILQENSTLSASNKCCING-------ASTVVTAIFGGILQNEVNCLIC 327 Query: 940 HKKSRTFEAFMYLSLPLASTSK------------CTLQDCLRLFSKEEKLTDNNRFYCSH 987 +SR F+ F+ LSL + S + C+L+DCLR F+ E+L + + C Sbjct: 328 GTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELYMCHK 387 Query: 988 CRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNN 1047 C+ ++ S KK I KLP VL +HLKRF + + K+ T V+FPL LD+ Y++ P+N+ Sbjct: 388 CKKKQKSTKKFWIQKLPKVLCLHLKRFHWTAYLRNKVDTYVEFPLRGLDMKCYLLEPENS 447 Query: 1048 LKK---YNLFSVSNHYG-GLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYI 1103 + Y+L +V H+G G+ GHYTAY + RWF F+D V+ +V + AYI Sbjct: 448 GPESCLYDLAAVVVHHGSGVGSGHYTAYATHEG--RWFHFNDSTVTLTDEETVVKAKAYI 505 Query: 1104 LFY 1106 LFY Sbjct: 506 LFY 508 >gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens] Length = 963 Score = 190 bits (482), Expect = 7e-48 Identities = 93/192 (48%), Positives = 122/192 (63%) Query: 774 PALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGII 833 P + GL NLGNTC+MNS LQCL N P L +YF NCY +++N N LG KGE+AE + + Sbjct: 306 PGICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNCYLEELNFRNPLGMKGEIAEAYADL 365 Query: 834 MKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRY 893 +K W+G +R I P FK +G QF GY Q DSQELL FL+DGLHEDLN+ ++ Sbjct: 366 VKQAWSGHHRSIVPHVFKNKVGHFASQFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYV 425 Query: 894 KEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLS 953 + + D + A+ AWQ HK+ N+S+IV F G FKST+ C C S TF+ F YLS Sbjct: 426 ELCDAAGRPDQEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLS 485 Query: 954 LPLASTSKCTLQ 965 +PL + K L+ Sbjct: 486 VPLPISHKRVLE 497 Score = 146 bits (369), Expect = 9e-35 Identities = 66/147 (44%), Positives = 99/147 (67%), Gaps = 4/147 (2%) Query: 964 LQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQK 1023 LQ+C+ LF+ E L N +YC C+ + + KK+++W LP +L++HLKRFSY ++K Sbjct: 781 LQECIELFTTVETLEKENPWYCPSCKQHQLATKKLDLWMLPEILIIHLKRFSYTKFSREK 840 Query: 1024 LQTSVDFPLENLDLSQYVIGPKN----NLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQR 1079 L T V+FP+ +LD S++VI P+N L KY+L +VSNHYGG+ GHYT + N + Sbjct: 841 LDTLVEFPIRDLDFSEFVIQPQNESNPELYKYDLIAVSNHYGGMRDGHYTTFACNKDSGQ 900 Query: 1080 WFKFDDHEVSDISVSSVKSSAAYILFY 1106 W FDD+ VS ++ + ++S AAY+LFY Sbjct: 901 WHYFDDNSVSPVNENQIESKAAYVLFY 927 >gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens] Length = 963 Score = 189 bits (480), Expect = 1e-47 Identities = 90/183 (49%), Positives = 124/183 (67%) Query: 774 PALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGII 833 P L GL NLGNTC+MNS LQCL N L DYF ++ Y+ +INR N LG KGE+AE + + Sbjct: 299 PGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAYAEL 358 Query: 834 MKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRY 893 +K +W+G+ +++P+ FK +G+ QF+GY QQDSQELL FL+DGLHEDLN+ + Sbjct: 359 IKQMWSGRDAHVAPRMFKTQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKKPYL 418 Query: 894 KEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLS 953 + ++ + D A+ AW+ H+ N+S+IV F G FKST+ C C K S TF+ F YL+ Sbjct: 419 ELKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFCYLT 478 Query: 954 LPL 956 LPL Sbjct: 479 LPL 481 Score = 145 bits (365), Expect = 3e-34 Identities = 63/143 (44%), Positives = 94/143 (65%) Query: 964 LQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQK 1023 L+DC+ LF+ E L +++ +YC +C+ + + KK ++W LP +L+VHLKRFSY+ W+ K Sbjct: 778 LRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNRYWRDK 837 Query: 1024 LQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKF 1083 L T V+FP+ L++S++V Y+L +VSNHYG + GHYTAY KN +W+ F Sbjct: 838 LDTVVEFPIRGLNMSEFVCNLSARPYVYDLIAVSNHYGAMGVGHYTAYAKNKLNGKWYYF 897 Query: 1084 DDHEVSDISVSSVKSSAAYILFY 1106 DD VS S + + AAY+LFY Sbjct: 898 DDSNVSLASEDQIVTKAAYVLFY 920 >gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens] Length = 916 Score = 189 bits (480), Expect = 1e-47 Identities = 90/183 (49%), Positives = 124/183 (67%) Query: 774 PALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGII 833 P L GL NLGNTC+MNS LQCL N L DYF ++ Y+ +INR N LG KGE+AE + + Sbjct: 252 PGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAYAEL 311 Query: 834 MKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRY 893 +K +W+G+ +++P+ FK +G+ QF+GY QQDSQELL FL+DGLHEDLN+ + Sbjct: 312 IKQMWSGRDAHVAPRMFKTQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKKPYL 371 Query: 894 KEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLS 953 + ++ + D A+ AW+ H+ N+S+IV F G FKST+ C C K S TF+ F YL+ Sbjct: 372 ELKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFCYLT 431 Query: 954 LPL 956 LPL Sbjct: 432 LPL 434 Score = 145 bits (365), Expect = 3e-34 Identities = 63/143 (44%), Positives = 94/143 (65%) Query: 964 LQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQK 1023 L+DC+ LF+ E L +++ +YC +C+ + + KK ++W LP +L+VHLKRFSY+ W+ K Sbjct: 731 LRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNRYWRDK 790 Query: 1024 LQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKF 1083 L T V+FP+ L++S++V Y+L +VSNHYG + GHYTAY KN +W+ F Sbjct: 791 LDTVVEFPIRGLNMSEFVCNLSARPYVYDLIAVSNHYGAMGVGHYTAYAKNKLNGKWYYF 850 Query: 1084 DDHEVSDISVSSVKSSAAYILFY 1106 DD VS S + + AAY+LFY Sbjct: 851 DDSNVSLASEDQIVTKAAYVLFY 873 >gi|57529246 ubiquitin thioesterase 19 [Homo sapiens] Length = 1318 Score = 179 bits (455), Expect = 1e-44 Identities = 108/280 (38%), Positives = 144/280 (51%), Gaps = 13/280 (4%) Query: 691 STPPTHKAKPQIPAERDREPSKLKRSYSSPDITQAIQEEEKRKPT--VTP---TVNRENK 745 STPP P E R K K S D + R P VTP T K Sbjct: 406 STPPGGAPHPLTGQEEARAVEKDKSKARSEDT--GLDSVATRTPMEHVTPKPETHLASPK 463 Query: 746 PTCY----PKAEISRLSASQIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHL 801 PTC P + +S S + P TGL NLGNTC+MNS++Q L N L Sbjct: 464 PTCMVPPMPHSPVSGDSVEEEEEEEKKV--CLPGFTGLVNLGNTCFMNSVIQSLSNTREL 521 Query: 802 ADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQF 861 D+F+ ++ +IN +N LG G +A F ++++ALW G + P K + QF Sbjct: 522 RDFFHDRSFEAEINYNNPLGTGGRLAIGFAVLLRALWKGTHHAFQPSKLKAIVASKASQF 581 Query: 862 AGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESI 921 GY+Q D+QE + FL+DGLHEDLN+ N+ + ++D D AE AWQ+HK N+S Sbjct: 582 TGYAQHDAQEFMAFLLDGLHEDLNRIQNKPYTETVDSDGRPDEVVAEEAWQRHKMRNDSF 641 Query: 922 IVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSK 961 IV LFQGQ+KS + C C K S TF+ F+YL +PL K Sbjct: 642 IVDLFQGQYKSKLVCPVCAKVSITFDPFLYLPVPLPQKQK 681 Score = 131 bits (330), Expect = 3e-30 Identities = 81/232 (34%), Positives = 123/232 (53%), Gaps = 28/232 (12%) Query: 887 ADNRKRYKEENND---HLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKS 943 + NR++ E+ D L D + W+ +++L E ++VA ++C Sbjct: 996 SSNREQRLEDKGDTPLELGDDCSLALVWRNNERLQEFVLVA------SKELEC--AEDPG 1047 Query: 944 RTFEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKL 1003 EA A TL CL LF++ E L +YC C+ R++ K++ +W+L Sbjct: 1048 SAGEA--------ARAGHFTLDQCLNLFTRPEVLAPEEAWYCPQCKQHREASKQLLLWRL 1099 Query: 1004 PPVLLVHLKRFSYDG-RWKQKLQTSVDFPLENLDLSQYVIGPK-NNLKKYNLFSVSNHYG 1061 P VL+V LKRFS+ W+ K+ V+FP+ NLDLS++ IG K L Y+L++V NHYG Sbjct: 1100 PNVLIVQLKRFSFRSFIWRDKINDLVEFPVRNLDLSKFCIGQKEEQLPSYDLYAVINHYG 1159 Query: 1062 GLDGGHYTAYCK---NAARQR----WFKFDDHEVSDISVSSVKSSAAYILFY 1106 G+ GGHYTA + + + QR W FDD V+ + S V + AY+LFY Sbjct: 1160 GMIGGHYTACARLPNDRSSQRSDVGWRLFDDSTVTTVDESQVVTRYAYVLFY 1211 >gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens] Length = 525 Score = 169 bits (429), Expect = 1e-41 Identities = 126/421 (29%), Positives = 186/421 (44%), Gaps = 66/421 (15%) Query: 724 QAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSASQIRNLNPVFGGSGPALTGLRNLG 783 + I +EE+RK V + K E+ L + R + L GL NLG Sbjct: 125 EIIAKEEQRKAWKMQGVGEKFSTWEPTKRELELLKHNPKRR--KITSNCTIGLRGLINLG 182 Query: 784 NTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYR 843 NTC+MN I+Q L + P L D+F D +R + + E + + ++G Sbjct: 183 NTCFMNCIVQALTHTPLLRDFF-----LSDRHRCEMQSPSSCLVCEMSSLFQEFYSGHRS 237 Query: 844 YISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDD 903 P + AGY QQD+ E L+ +D LH DN K K N +H + Sbjct: 238 PHIPYKLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDNGK--KANNPNHCN- 294 Query: 904 FKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSK-- 961 II +F G +S V C CH S T + F +SL L +S Sbjct: 295 ----------------CIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPF 338 Query: 962 ---------------------CTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEI 1000 TL DCLR F++ E L + + CS C + ++S K++ + Sbjct: 339 WPLSPGSEGNVVNGESHVSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTM 398 Query: 1001 WKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPK--------------- 1045 KLP V HLKRF + + ++K+ T V FPLE LD++ ++ K Sbjct: 399 KKLPIVACFHLKRFEHSAKLRRKITTYVSFPLE-LDMTPFMASSKESRMNGQYQQPTDSL 457 Query: 1046 NNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILF 1105 NN KY+LF+V NH G L+ GHYT++ + + +WFK DD ++ S+ V S Y+LF Sbjct: 458 NNDNKYSLFAVVNHQGTLESGHYTSFIRQ-HKDQWFKCDDAIITKASIKDVLDSEGYLLF 516 Query: 1106 Y 1106 Y Sbjct: 517 Y 517 >gi|109638751 ubiquitin specific protease 6 [Homo sapiens] Length = 1406 Score = 167 bits (424), Expect = 4e-41 Identities = 91/223 (40%), Positives = 133/223 (59%), Gaps = 5/223 (2%) Query: 744 NKPTCYPKAEISRLSASQI-RNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLA 802 NK +P+ ++S+I R P G+ TGL NLGNTC+MNS +QC+ N L Sbjct: 502 NKDMSWPEEMSFTANSSKIDRQKVPTEKGA----TGLSNLGNTCFMNSSIQCVSNTQPLT 557 Query: 803 DYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFA 862 YF + ++NR+N +G KG +A+ +G +++ LW+G + ++P + TI K +F Sbjct: 558 QYFISGRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKSVAPLKLRRTIAKYAPKFD 617 Query: 863 GYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESII 922 G+ QQDSQELL FL+DGLHEDLN+ + + +++D D++ A AW H + N SII Sbjct: 618 GFQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSDGRPDWEVAAEAWDNHLRRNRSII 677 Query: 923 VALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQ 965 V LF GQ +S V+C TC S F+ F +LSLPL S L+ Sbjct: 678 VDLFHGQLRSQVKCKTCGHISVRFDPFNFLSLPLPMDSYMDLE 720 Score = 70.5 bits (171), Expect = 9e-12 Identities = 32/86 (37%), Positives = 50/86 (58%) Query: 957 ASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSY 1016 A L CLR F+ EE+L ++ +YCS C+ + KK+++W+LPP L++HLKRF + Sbjct: 1026 AQAEPINLDSCLRAFTSEEELGESEMYYCSKCKTHCLATKKLDLWRLPPFLIIHLKRFQF 1085 Query: 1017 DGRWKQKLQTSVDFPLENLDLSQYVI 1042 K Q V F E+ D S +++ Sbjct: 1086 VNDQWIKSQKIVRFLRESFDPSAFLV 1111 Score = 53.1 bits (126), Expect = 1e-06 Identities = 23/60 (38%), Positives = 35/60 (58%), Gaps = 1/60 (1%) Query: 1051 YNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFYTSLG 1110 YNL+++S H G L GGHY Y KN +W+ ++D ++ + + +AYILFY G Sbjct: 1312 YNLYAISCHSGILSGGHYITYAKN-PNCKWYCYNDSSCEELHPDEIDTDSAYILFYEQQG 1370 >gi|22550104 ubiquitin specific protease 32 [Homo sapiens] Length = 1604 Score = 166 bits (421), Expect = 9e-41 Identities = 90/223 (40%), Positives = 134/223 (60%), Gaps = 5/223 (2%) Query: 744 NKPTCYPKAEISRLSASQI-RNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLA 802 NK +P+ ++S+I R+ P G+ TGL NLGNTC+MNS +QC+ N L Sbjct: 704 NKDMSWPEEMSFIANSSKIDRHKVPTEKGA----TGLSNLGNTCFMNSSIQCVSNTQPLT 759 Query: 803 DYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFA 862 YF + ++NR+N +G KG +A+ +G +++ LW+G + ++P + TI K +F Sbjct: 760 QYFISGRHLYELNRTNPIGMKGHMAKCYGDLVQELWSGTQKNVAPLKLRWTIAKYAPRFN 819 Query: 863 GYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESII 922 G+ QQDSQELL FL+DGLHEDLN+ + + +++D D++ A AW H + N SI+ Sbjct: 820 GFQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSDGRPDWEVAAEAWDNHLRRNRSIV 879 Query: 923 VALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQ 965 V LF GQ +S V+C TC S F+ F +LSLPL S L+ Sbjct: 880 VDLFHGQLRSQVKCKTCGHISVRFDPFNFLSLPLPMDSYMHLE 922 Score = 81.6 bits (200), Expect = 4e-15 Identities = 37/87 (42%), Positives = 56/87 (64%), Gaps = 2/87 (2%) Query: 957 ASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSY 1016 A L CLR F+ EE+L +N +YCS C+ + KK+++W+LPP+L++HLKRF + Sbjct: 1228 AQAEPINLDSCLRAFTSEEELGENEMYYCSKCKTHCLATKKLDLWRLPPILIIHLKRFQF 1287 Query: 1017 -DGRWKQKLQTSVDFPLENLDLSQYVI 1042 +GRW K Q V FP E+ D S +++ Sbjct: 1288 VNGRW-IKSQKIVKFPRESFDPSAFLV 1313 Score = 53.1 bits (126), Expect = 1e-06 Identities = 23/60 (38%), Positives = 35/60 (58%), Gaps = 1/60 (1%) Query: 1051 YNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFYTSLG 1110 YNL+++S H G L GGHY Y KN +W+ ++D ++ + + +AYILFY G Sbjct: 1510 YNLYAISCHSGILGGGHYVTYAKN-PNCKWYCYNDSSCKELHPDEIDTDSAYILFYEQQG 1568 >gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens] Length = 438 Score = 157 bits (396), Expect = 7e-38 Identities = 111/373 (29%), Positives = 172/373 (46%), Gaps = 73/373 (19%) Query: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835 L GL NLGNTC+MN I+Q L + P L D+F + ++ ++ L + E + + Sbjct: 77 LRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELC-----LVCEMSSLFR 131 Query: 836 ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLH-----EDLNKADNR 890 L++G P + AGY QQD+ E L+ +D LH +D+ KA N Sbjct: 132 ELYSGNPSPHVPYKLLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRHCKGDDVGKAAN- 190 Query: 891 KRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFM 950 N +H + II +F G +S V C CH S T + Sbjct: 191 ------NPNHCN-----------------CIIDQIFTGGLQSDVTCQACHGVSTTIDPCW 227 Query: 951 YLSLPLASTSKC----------------------TLQDCLRLFSKEEKLTDNNRFYCSHC 988 +SL L + TL DCLR F++ E L + + C C Sbjct: 228 DISLDLPGSCTSFWPMSPGRESSVNGESHIPGITTLTDCLRRFTRPEHLGSSAKIKCGSC 287 Query: 989 RARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPK--- 1045 ++ ++S K++ + KLP V H KRF + + ++K+ T + FPLE LD++ ++ K Sbjct: 288 QSYQESTKQLTMNKLPVVACFHFKRFEHSAKQRRKITTYISFPLE-LDMTPFMASSKESR 346 Query: 1046 ------------NNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISV 1093 NN KY+LF+V NH G L+ GHYT++ ++ + +WFK DD ++ S+ Sbjct: 347 MNGQLQLPTNSGNNENKYSLFAVVNHQGTLESGHYTSFIRH-HKDQWFKCDDAVITKASI 405 Query: 1094 SSVKSSAAYILFY 1106 V S Y+LFY Sbjct: 406 KDVLDSEGYLLFY 418 >gi|41152235 ubiquitin specific protease 51 [Homo sapiens] Length = 711 Score = 153 bits (386), Expect = 1e-36 Identities = 106/372 (28%), Positives = 171/372 (45%), Gaps = 63/372 (16%) Query: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835 L GL NLGNTC+MN I+Q L + P L D+F + ++ + +L + E + Sbjct: 362 LRGLINLGNTCFMNCIVQALTHIPLLKDFFLSDKHKCIMTSPSLC-----LVCEMSSLFH 416 Query: 836 ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKE 895 A+++G P I + AGY QQD+ E L+ ++D LH Sbjct: 417 AMYSGSRTPHIPYKLLHLIWIHAEHLAGYRQQDAHEFLIAILDVLHR------------- 463 Query: 896 ENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLP 955 H D + A + II +F G +S V C CH S T + +SL Sbjct: 464 ----HSKDDSGGQEA--NNPNCCNCIIDQIFTGGLQSDVTCQACHSVSTTIDPCWDISLD 517 Query: 956 LASTSKC-----------------------TLQDCLRLFSKEEKLTDNNRFYCSHCRARR 992 L + +L DCL+ F++ E L + + C+ C++ + Sbjct: 518 LPGSCATFDSQNPERADSTVSRDDHIPGIPSLTDCLQWFTRPEHLGSSAKIKCNSCQSYQ 577 Query: 993 DSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKN------ 1046 +S K++ + KLP V HLKRF + G+ ++K+ T + FPLE LD++ ++ K Sbjct: 578 ESTKQLTMKKLPIVACFHLKRFEHVGKQRRKINTFISFPLE-LDMTPFLASTKESRMKEG 636 Query: 1047 --------NLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKS 1098 N KY+LF+V NH+G L+ GHYT++ + + +WF DD ++ ++ + Sbjct: 637 QPPTDCVPNENKYSLFAVINHHGTLESGHYTSFIRQ-QKDQWFSCDDAIITKATIEDLLY 695 Query: 1099 SAAYILFYTSLG 1110 S Y+LFY G Sbjct: 696 SEGYLLFYHKQG 707 >gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens] Length = 712 Score = 141 bits (356), Expect = 3e-33 Identities = 137/504 (27%), Positives = 209/504 (41%), Gaps = 111/504 (22%) Query: 701 QIPAERDREPSKLKRSYSSPDITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSAS 760 Q+ AE + P + + I+ + P TP ++K + EIS+ + Sbjct: 200 QVKAELESMPPRKSLRLQGLAQSTIIEIVSVQVPAQTPASPAKDKVLSTSENEISQKVSD 259 Query: 761 QIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCL------------------------- 795 P+ P +TGLRNLGNTCYMNS+LQ L Sbjct: 260 SSVKRRPIVT---PGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASE 316 Query: 796 ----CNAPHLAD---YFNRNCYQDDI----NRSNLL----------GHKGEVAE------ 828 C P + D Y C + D +R + L G K E+ + Sbjct: 317 KTRSCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTS 376 Query: 829 -------EFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLH 881 E + + +W+G++ +SP ++ ++ F GY+QQD+QE L L+D + Sbjct: 377 QYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQ 436 Query: 882 EDLNKADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHK 941 +L E L + LN ++ +F GQ S V CL C Sbjct: 437 REL----------ETTGTSLPALIPTSQRKLIKQVLN--VVNNIFHGQLLSQVTCLACDN 484 Query: 942 KSRTFEAFMYLSLPLASTSKCTLQDC----------LRLFSKEEKLTDNNRFYCSHCRAR 991 KS T E F LSL +C+ +D L F++ E L + + C C ++ Sbjct: 485 KSNTIEPFWDLSLEFPERYQCSGKDIASQPCLVTEMLAKFTETEAL-EGKIYVCDQCNSK 543 Query: 992 R-----------DSLKKIEIWKLPPVLLVHLKRFSYDGRW-KQKLQTSVDFPLENLDLSQ 1039 R ++ K++ I LP VL +HLKRF + GR ++K+ V F E L++ Sbjct: 544 RRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFE-EILNMEP 602 Query: 1040 YVIGPKNNLKK-------YNLFSVSNHYG-GLDGGHYTAYCKNAARQRWFKFDDHEVSDI 1091 Y + LK Y+L +V H+G G GHYTAYC N+ W +D ++S Sbjct: 603 YCC--RETLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMC 660 Query: 1092 SVSSVKSSAAYILFYTSLGPRVTD 1115 ++ V + AYILFYT RVT+ Sbjct: 661 TMDEVCKAQAYILFYTQ---RVTE 681 >gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens] Length = 712 Score = 141 bits (356), Expect = 3e-33 Identities = 137/504 (27%), Positives = 209/504 (41%), Gaps = 111/504 (22%) Query: 701 QIPAERDREPSKLKRSYSSPDITQAIQEEEKRKPTVTPTVNRENKPTCYPKAEISRLSAS 760 Q+ AE + P + + I+ + P TP ++K + EIS+ + Sbjct: 200 QVKAELESMPPRKSLRLQGLAQSTIIEIVSVQVPAQTPASPAKDKVLSTSENEISQKVSD 259 Query: 761 QIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCL------------------------- 795 P+ P +TGLRNLGNTCYMNS+LQ L Sbjct: 260 SSVKRRPIVT---PGVTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASE 316 Query: 796 ----CNAPHLAD---YFNRNCYQDDI----NRSNLL----------GHKGEVAE------ 828 C P + D Y C + D +R + L G K E+ + Sbjct: 317 KTRSCKHPPVTDTVVYQMNECQEKDTGFVCSRQSSLSSGLSGGASKGRKMELIQPKEPTS 376 Query: 829 -------EFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLH 881 E + + +W+G++ +SP ++ ++ F GY+QQD+QE L L+D + Sbjct: 377 QYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQ 436 Query: 882 EDLNKADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHK 941 +L E L + LN ++ +F GQ S V CL C Sbjct: 437 REL----------ETTGTSLPALIPTSQRKLIKQVLN--VVNNIFHGQLLSQVTCLACDN 484 Query: 942 KSRTFEAFMYLSLPLASTSKCTLQDC----------LRLFSKEEKLTDNNRFYCSHCRAR 991 KS T E F LSL +C+ +D L F++ E L + + C C ++ Sbjct: 485 KSNTIEPFWDLSLEFPERYQCSGKDIASQPCLVTEMLAKFTETEAL-EGKIYVCDQCNSK 543 Query: 992 R-----------DSLKKIEIWKLPPVLLVHLKRFSYDGRW-KQKLQTSVDFPLENLDLSQ 1039 R ++ K++ I LP VL +HLKRF + GR ++K+ V F E L++ Sbjct: 544 RRRFSSKPVVLTEAQKQLMICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFE-EILNMEP 602 Query: 1040 YVIGPKNNLKK-------YNLFSVSNHYG-GLDGGHYTAYCKNAARQRWFKFDDHEVSDI 1091 Y + LK Y+L +V H+G G GHYTAYC N+ W +D ++S Sbjct: 603 YCC--RETLKSLRPECFIYDLSAVVMHHGKGFGSGHYTAYCYNSEGGFWVHCNDSKLSMC 660 Query: 1092 SVSSVKSSAAYILFYTSLGPRVTD 1115 ++ V + AYILFYT RVT+ Sbjct: 661 TMDEVCKAQAYILFYTQ---RVTE 681 >gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens] Length = 828 Score = 138 bits (347), Expect = 3e-32 Identities = 81/250 (32%), Positives = 121/250 (48%), Gaps = 48/250 (19%) Query: 905 KAAEHAWQKHKQLNE---SIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPL----- 956 K A+ A K K+ ++ S+I +F G S+VQCLTC + S T E F LSLP+ Sbjct: 455 KKAQSASPKRKKQHKKYRSVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKED 514 Query: 957 -------------ASTSKC--------------------------TLQDCLRLFSKEEKL 977 C TLQDCL F ++L Sbjct: 515 LAKLHSSSHPTSIVKAGSCGEAYAPQGWIAFFMEYVKSWFWGPVVTLQDCLAAFFARDEL 574 Query: 978 TDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDL 1037 +N + C C+ R+ +K ++ P +L +HLKRF ++ + K+ T V FPLE LDL Sbjct: 575 KGDNMYSCEKCKKLRNGVKFCKVQNFPEILCIHLKRFRHELMFSTKISTHVSFPLEGLDL 634 Query: 1038 SQYVI-GPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSV 1096 ++ + Y+L SV H+G GHY AYC+N W++FDD V+++S S+V Sbjct: 635 QPFLAKDSPAQIVTYDLLSVICHHGTASSGHYIAYCRNNLNNLWYEFDDQSVTEVSESTV 694 Query: 1097 KSSAAYILFY 1106 +++ AY+LFY Sbjct: 695 QNAEAYVLFY 704 Score = 72.4 bits (176), Expect = 2e-12 Identities = 44/112 (39%), Positives = 58/112 (51%), Gaps = 7/112 (6%) Query: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835 LTGL+N+GNTCYMN+ LQ L N P L +F D K + + + +M Sbjct: 184 LTGLKNIGNTCYMNAALQALSNCPPLTQFFL------DCGGLARTDKKPAICKSYLKLMT 237 Query: 836 ALW-TGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNK 886 LW + + P I +N F GYSQQD+QE L LMD LHE+L + Sbjct: 238 ELWHKSRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCLMDLLHEELKE 289 >gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens] Length = 942 Score = 135 bits (339), Expect = 3e-31 Identities = 81/258 (31%), Positives = 121/258 (46%), Gaps = 56/258 (21%) Query: 905 KAAEHAWQKHKQLNE---SIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLP------ 955 K A+ A K K+ ++ S+I +F G S+VQCLTC + S T E F LSLP Sbjct: 455 KKAQSASPKRKKQHKKYRSVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKED 514 Query: 956 ------------LASTSKC----------------------------------TLQDCLR 969 + C TLQDCL Sbjct: 515 LAKLHSSSHPTSIVKAGSCGEAYAPQGWIAFFMEYVKRFVVSCVPSWFWGPVVTLQDCLA 574 Query: 970 LFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVD 1029 F ++L +N + C C+ R+ +K ++ P +L +HLKRF ++ + K+ T V Sbjct: 575 AFFARDELKGDNMYSCEKCKKLRNGVKFCKVQNFPEILCIHLKRFRHELMFSTKISTHVS 634 Query: 1030 FPLENLDLSQYVI-GPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEV 1088 FPLE LDL ++ + Y+L SV H+G GHY AYC+N W++FDD V Sbjct: 635 FPLEGLDLQPFLAKDSPAQIVTYDLLSVICHHGTASSGHYIAYCRNNLNNLWYEFDDQSV 694 Query: 1089 SDISVSSVKSSAAYILFY 1106 +++S S+V+++ AY+LFY Sbjct: 695 TEVSESTVQNAEAYVLFY 712 Score = 72.4 bits (176), Expect = 2e-12 Identities = 44/112 (39%), Positives = 58/112 (51%), Gaps = 7/112 (6%) Query: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835 LTGL+N+GNTCYMN+ LQ L N P L +F D K + + + +M Sbjct: 184 LTGLKNIGNTCYMNAALQALSNCPPLTQFFL------DCGGLARTDKKPAICKSYLKLMT 237 Query: 836 ALW-TGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNK 886 LW + + P I +N F GYSQQD+QE L LMD LHE+L + Sbjct: 238 ELWHKSRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCLMDLLHEELKE 289 >gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens] Length = 911 Score = 135 bits (339), Expect = 3e-31 Identities = 81/258 (31%), Positives = 121/258 (46%), Gaps = 56/258 (21%) Query: 905 KAAEHAWQKHKQLNE---SIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLP------ 955 K A+ A K K+ ++ S+I +F G S+VQCLTC + S T E F LSLP Sbjct: 424 KKAQSASPKRKKQHKKYRSVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKED 483 Query: 956 ------------LASTSKC----------------------------------TLQDCLR 969 + C TLQDCL Sbjct: 484 LAKLHSSSHPTSIVKAGSCGEAYAPQGWIAFFMEYVKRFVVSCVPSWFWGPVVTLQDCLA 543 Query: 970 LFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVD 1029 F ++L +N + C C+ R+ +K ++ P +L +HLKRF ++ + K+ T V Sbjct: 544 AFFARDELKGDNMYSCEKCKKLRNGVKFCKVQNFPEILCIHLKRFRHELMFSTKISTHVS 603 Query: 1030 FPLENLDLSQYVI-GPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEV 1088 FPLE LDL ++ + Y+L SV H+G GHY AYC+N W++FDD V Sbjct: 604 FPLEGLDLQPFLAKDSPAQIVTYDLLSVICHHGTASSGHYIAYCRNNLNNLWYEFDDQSV 663 Query: 1089 SDISVSSVKSSAAYILFY 1106 +++S S+V+++ AY+LFY Sbjct: 664 TEVSESTVQNAEAYVLFY 681 Score = 72.4 bits (176), Expect = 2e-12 Identities = 44/112 (39%), Positives = 58/112 (51%), Gaps = 7/112 (6%) Query: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835 LTGL+N+GNTCYMN+ LQ L N P L +F D K + + + +M Sbjct: 153 LTGLKNIGNTCYMNAALQALSNCPPLTQFFL------DCGGLARTDKKPAICKSYLKLMT 206 Query: 836 ALW-TGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNK 886 LW + + P I +N F GYSQQD+QE L LMD LHE+L + Sbjct: 207 ELWHKSRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCLMDLLHEELKE 258 >gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens] Length = 370 Score = 133 bits (335), Expect = 8e-31 Identities = 110/358 (30%), Positives = 162/358 (45%), Gaps = 56/358 (15%) Query: 778 GLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK-- 835 GL N GNTCY NS+LQ L YF R R +L +K + ++ ++ Sbjct: 40 GLVNFGNTCYCNSVLQAL--------YFCRPF------REKVLAYKSQPRKKESLLTCLA 85 Query: 836 ------ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLM----DGLHEDLN 885 A + I PK F + K N+ F Y QQD+ E L +L+ D L E+ Sbjct: 86 DLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERK 145 Query: 886 KADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRT 945 + R N D+ ++ + W + +FQG + +CLTC S Sbjct: 146 QEKQNGRLPNGNIDNENNNSTPDPTW----------VDEIFQGTLTNETRCLTCETISSK 195 Query: 946 FEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPP 1005 E F+ LS+ + + T CLR FS E L ++YC CR+++++ K++++ KLP Sbjct: 196 DEDFLDLSVDVEQNTSIT--HCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPM 253 Query: 1006 VLLVHLKRFSYDGRWKQ--KLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYG-G 1062 +L +HLKRF Y + + KL V FPLE L L N + Y+L +V H G G Sbjct: 254 ILALHLKRFKYMDQLHRYTKLSYRVVFPLE-LRLFNTSGDATNPDRMYDLVAVVVHCGSG 312 Query: 1063 LDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVK------------SSAAYILFYTS 1108 + GHY A K + W FDD V I +++ S + YILFY S Sbjct: 313 PNRGHYIAIVK--SHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQS 368 >gi|148612811 ubiquitin specific protease 43 [Homo sapiens] Length = 1123 Score = 131 bits (330), Expect = 3e-30 Identities = 61/168 (36%), Positives = 96/168 (57%), Gaps = 23/168 (13%) Query: 962 CTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWK 1021 CTL +C + ++KEE+L ++ + C HC+ + + K+ +W LP +L++HLKRF G + Sbjct: 540 CTLDECFQFYTKEEQLAQDDAWKCPHCQVLQQGMVKLSLWTLPDILIIHLKRFCQVGERR 599 Query: 1022 QKLQTSVDFPLENLDLSQYV----------IGPKNNLKK-------------YNLFSVSN 1058 KL T V FPL L+++ +V +GP + K+ Y+L++V N Sbjct: 600 NKLSTLVKFPLSGLNMAPHVAQRSTSPEAGLGPWPSWKQPDCLPTSYPLDFLYDLYAVCN 659 Query: 1059 HYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFY 1106 H+G L GGHYTAYC+N+ +W+ +DD V + V + AYILFY Sbjct: 660 HHGNLQGGHYTAYCRNSLDGQWYSYDDSTVEPLREDEVNTRGAYILFY 707 Score = 112 bits (280), Expect = 2e-24 Identities = 65/189 (34%), Positives = 101/189 (53%), Gaps = 12/189 (6%) Query: 770 GGSGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEE 829 G P GL+N GNTC+MN+++QCL N LA++ Y+ R+ EV E+ Sbjct: 94 GARPPGAQGLKNHGNTCFMNAVVQCLSNTDLLAEFLALGRYRAAPGRA-------EVTEQ 146 Query: 830 FGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADN 889 +++ALWT +Y +FK + K QF G SQ D+ E LL+L+D +HEDL + Sbjct: 147 LAALVRALWTREYTPQLSAEFKNAVSKYGSQFQGNSQHDALEFLLWLLDRVHEDL---EG 203 Query: 890 RKRYKEENNDHLDDFKAAEHAWQKHKQ--LNESIIVALFQGQFKSTVQCLTCHKKSRTFE 947 R + K +E+ Q L +S + + FQ Q++S++ C C K+S TF+ Sbjct: 204 SSRGPVSEKLPPEATKTSENCLSPSAQLPLGQSFVQSHFQAQYRSSLTCPHCLKQSNTFD 263 Query: 948 AFMYLSLPL 956 F+ +SLP+ Sbjct: 264 PFLCVSLPI 272 >gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo sapiens] Length = 359 Score = 130 bits (327), Expect = 7e-30 Identities = 109/354 (30%), Positives = 164/354 (46%), Gaps = 48/354 (13%) Query: 778 GLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK-- 835 GL N GNTCY NS+LQ L YF R R N+L +K + ++ ++ Sbjct: 29 GLVNFGNTCYCNSVLQAL--------YFCRPF------RENVLAYKAQQKKKENLLTCLA 74 Query: 836 ------ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADN 889 A + I PK F + K ND F Y QQD+ E L +L++ + + L + Sbjct: 75 DLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQE--- 131 Query: 890 RKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAF 949 ++ +E+ N L + E A +L + + +FQG + +CL C S E F Sbjct: 132 -EKKQEKQNGKLKNGNMNEPAENNKPEL--TWVHEIFQGTLTNETRCLNCETVSSKDEDF 188 Query: 950 MYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLV 1009 + LS+ + + T CLR FS E L ++YC C +++++ K++ + KLP +L + Sbjct: 189 LDLSVDVEQNTSIT--HCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILAL 246 Query: 1010 HLKRFSYDGRWKQ--KLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYG-GLDGG 1066 HLKRF Y + + KL V FPLE L L N + Y+L +V H G G + G Sbjct: 247 HLKRFKYMEQLHRYTKLSYRVVFPLE-LRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRG 305 Query: 1067 HYTAYCKNAARQRWFKFDDHEVSDISVSSVK------------SSAAYILFYTS 1108 HY K + W FDD V I +++ S + YILFY S Sbjct: 306 HYITIVK--SHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQS 357 >gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo sapiens] Length = 366 Score = 130 bits (327), Expect = 7e-30 Identities = 109/354 (30%), Positives = 164/354 (46%), Gaps = 48/354 (13%) Query: 778 GLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK-- 835 GL N GNTCY NS+LQ L YF R R N+L +K + ++ ++ Sbjct: 36 GLVNFGNTCYCNSVLQAL--------YFCRPF------RENVLAYKAQQKKKENLLTCLA 81 Query: 836 ------ALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADN 889 A + I PK F + K ND F Y QQD+ E L +L++ + + L + Sbjct: 82 DLFHSIATQKKKVGVIPPKKFISRLRKENDLFDNYMQQDAHEFLNYLLNTIADILQE--- 138 Query: 890 RKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAF 949 ++ +E+ N L + E A +L + + +FQG + +CL C S E F Sbjct: 139 -EKKQEKQNGKLKNGNMNEPAENNKPEL--TWVHEIFQGTLTNETRCLNCETVSSKDEDF 195 Query: 950 MYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLV 1009 + LS+ + + T CLR FS E L ++YC C +++++ K++ + KLP +L + Sbjct: 196 LDLSVDVEQNTSIT--HCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPMILAL 253 Query: 1010 HLKRFSYDGRWKQ--KLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYG-GLDGG 1066 HLKRF Y + + KL V FPLE L L N + Y+L +V H G G + G Sbjct: 254 HLKRFKYMEQLHRYTKLSYRVVFPLE-LRLFNTSSDAVNLDRMYDLVAVVVHCGSGPNRG 312 Query: 1067 HYTAYCKNAARQRWFKFDDHEVSDISVSSVK------------SSAAYILFYTS 1108 HY K + W FDD V I +++ S + YILFY S Sbjct: 313 HYITIVK--SHGFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQS 364 >gi|120587027 ubiquitin specific peptidase 31 [Homo sapiens] Length = 1352 Score = 130 bits (327), Expect = 7e-30 Identities = 63/169 (37%), Positives = 95/169 (56%), Gaps = 26/169 (15%) Query: 962 CTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWK 1021 CTL C +L++KEE+L ++ + C HC+ + + +W LP VL++HLKRF +G + Sbjct: 596 CTLSQCFQLYTKEERLAPDDAWRCPHCKQLQQGSITLSLWTLPDVLIIHLKRFRQEGDRR 655 Query: 1022 QKLQTSVDFPLENLDLSQYVI------------------------GPKNNLKKYNLFSVS 1057 KLQ V FPL LD++ +V+ P++ + Y+L++V Sbjct: 656 MKLQNMVKFPLTGLDMTPHVVKRSQSSWSLPSHWSPWRRPYGLGRDPEDYI--YDLYAVC 713 Query: 1058 NHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFY 1106 NH+G + GGHYTAYCKN+ W+ FDD +V +S V + AYILFY Sbjct: 714 NHHGTMQGGHYTAYCKNSVDGLWYCFDDSDVQQLSEDEVCTQTAYILFY 762 Score = 109 bits (273), Expect = 1e-23 Identities = 66/192 (34%), Positives = 101/192 (52%), Gaps = 13/192 (6%) Query: 774 PALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQ-------DDINRSNLLGHKG-- 824 P + GLRN GNTC+MN+ LQCL N A+Y Y+ D + G +G Sbjct: 125 PGVAGLRNHGNTCFMNATLQCLSNTELFAEYLALGQYRAGRPEPSPDPEQPAGRGAQGQG 184 Query: 825 EVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDL 884 EV E+ +++ALWT +Y +DFK + K Q+ G SQ D+QE LL+L+D +HEDL Sbjct: 185 EVTEQLAHLVRALWTLEYTPQHSRDFKTIVSKNALQYRGNSQHDAQEFLLWLLDRVHEDL 244 Query: 885 NKADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSR 944 N + + D ++ + + + LFQ Q++S++ C C K+S Sbjct: 245 NHSVKQSGQPPLKPPSETDMMPEGPSF----PVCSTFVQELFQAQYRSSLTCPHCQKQSN 300 Query: 945 TFEAFMYLSLPL 956 TF+ F+ +SLP+ Sbjct: 301 TFDPFLCISLPI 312 >gi|183396780 ubiquitin specific protease 20 [Homo sapiens] Length = 914 Score = 130 bits (326), Expect = 9e-30 Identities = 74/248 (29%), Positives = 117/248 (47%), Gaps = 53/248 (21%) Query: 912 QKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPL--------------- 956 ++ +Q S+I +F G S VQCLTC + S T E F LSLP+ Sbjct: 435 RRKEQRYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPIPGKEDLAKLHSAIYQ 494 Query: 957 ---ASTSKC----------------------------------TLQDCLRLFSKEEKLTD 979 A C TL+DCL F ++L Sbjct: 495 NVPAKPGACGDSYAAQGWLAFIVEYIRRFVVSCTPSWFWGPVVTLEDCLAAFFAADELKG 554 Query: 980 NNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQ 1039 +N + C C+ R+ +K ++ +LP +L +HLKRF ++ + K+ + V FPLE LDL Sbjct: 555 DNMYSCERCKKLRNGVKYCKVLRLPEILCIHLKRFRHEVMYSFKINSHVSFPLEGLDLRP 614 Query: 1040 YVIGP-KNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKS 1098 ++ + + Y+L SV H+G GHY AYC+N +W++FDD V+++ + V++ Sbjct: 615 FLAKECTSQITTYDLLSVICHHGTAGSGHYIAYCQNVINGQWYEFDDQYVTEVHETVVQN 674 Query: 1099 SAAYILFY 1106 + Y+LFY Sbjct: 675 AEGYVLFY 682 Score = 71.6 bits (174), Expect = 4e-12 Identities = 42/112 (37%), Positives = 63/112 (56%), Gaps = 7/112 (6%) Query: 776 LTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMK 835 LTG++NLGN+CYMN+ LQ L N P L +F C + R++ K + + + ++ Sbjct: 144 LTGMKNLGNSCYMNAALQALSNCPPLTQFF-LEC--GGLVRTD---KKPALCKSYQKLVS 197 Query: 836 ALW-TGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNK 886 +W + Y+ P I +N F GY+QQD+QE L LMD LHE+L + Sbjct: 198 EVWHKKRPSYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRCLMDQLHEELKE 249 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.129 0.369 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 45,951,611 Number of Sequences: 37866 Number of extensions: 2386952 Number of successful extensions: 54911 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1171 Number of HSP's successfully gapped in prelim test: 1247 Number of HSP's that attempted gapping in prelim test: 14952 Number of HSP's gapped (non-prelim): 19120 length of query: 1118 length of database: 18,247,518 effective HSP length: 113 effective length of query: 1005 effective length of database: 13,968,660 effective search space: 14038503300 effective search space used: 14038503300 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.