Search of human proteins with 190014605

Search of human proteins with 190014605

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|190014605 programmed cell death 1 ligand 2 [Homo sapiens]
         (273 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|190014605 programmed cell death 1 ligand 2 [Homo sapiens]          552   e-157
gi|7661534 CD274 molecule [Homo sapiens]                              150   1e-36
gi|67188443 CD276 antigen isoform a [Homo sapiens]                     71   9e-13
gi|34932496 butyrophilin, subfamily 3, member A2 precursor [Homo...    71   1e-12
gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]       70   2e-12
gi|13376852 CD276 antigen isoform b [Homo sapiens]                     70   3e-12
gi|5901908 butyrophilin, subfamily 3, member A3 isoform a [Homo ...    67   2e-11
gi|37574628 butyrophilin, subfamily 3, member A3 isoform b [Homo...    60   2e-09
gi|37221189 butyrophilin, subfamily 3, member A1 isoform b [Homo...    59   5e-09
gi|222418660 butyrophilin, subfamily 3, member A1 isoform d [Hom...    59   5e-09
gi|37595558 butyrophilin, subfamily 3, member A1 isoform a [Homo...    59   5e-09
gi|6453813 butyrophilin, subfamily 2, member A2 isoform a [Homo ...    54   1e-07
gi|27477039 inducible T-cell co-stimulator ligand [Homo sapiens]       53   2e-07
gi|5921461 butyrophilin, subfamily 2, member A1 isoform 1 precur...    51   9e-07
gi|17975772 butyrophilin, subfamily 2, member A1 isoform 2 precu...    51   9e-07
gi|54607118 leucine-rich repeats and immunoglobulin-like domains...    45   5e-05
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]                    43   3e-04
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]                    43   3e-04
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]                    43   3e-04
gi|118572606 hemicentin 1 [Homo sapiens]                               43   3e-04
gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]       43   3e-04
gi|222418658 butyrophilin, subfamily 3, member A1 isoform c [Hom...    43   3e-04
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]             42   6e-04
gi|99028881 V-set domain containing T cell activation inhibitor ...    41   0.001
gi|5031927 skeletal muscle receptor tyrosine kinase [Homo sapiens]     41   0.001
gi|4885123 CD80 antigen precursor [Homo sapiens]                       40   0.002
gi|90903245 CD200 antigen isoform b [Homo sapiens]                     40   0.003
gi|90903247 CD200 antigen isoform a precursor [Homo sapiens]           40   0.003
gi|157739930 TAP binding protein-like [Homo sapiens]                   40   0.003
gi|139948432 adlican [Homo sapiens]                                    40   0.003

>gi|190014605 programmed cell death 1 ligand 2 [Homo sapiens]
          Length = 273

 Score =  552 bits (1422), Expect = e-157
 Identities = 273/273 (100%), Positives = 273/273 (100%)

Query: 1   MIFLLLMLSLELQLHQIAALFTVTVPKELYIIEHGSNVTLECNFDTGSHVNLGAITASLQ 60
           MIFLLLMLSLELQLHQIAALFTVTVPKELYIIEHGSNVTLECNFDTGSHVNLGAITASLQ
Sbjct: 1   MIFLLLMLSLELQLHQIAALFTVTVPKELYIIEHGSNVTLECNFDTGSHVNLGAITASLQ 60

Query: 61  KVENDTSPHRERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVK 120
           KVENDTSPHRERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVK
Sbjct: 61  KVENDTSPHRERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVK 120

Query: 121 ASYRKINTHILKVPETDEVELTCQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVL 180
           ASYRKINTHILKVPETDEVELTCQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVL
Sbjct: 121 ASYRKINTHILKVPETDEVELTCQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVL 180

Query: 181 RLKPPPGRNFSCVFWNTHVRELTLASIDLQSQMEPRTHPTWLLHIFIPFCIIAFIFIATV 240
           RLKPPPGRNFSCVFWNTHVRELTLASIDLQSQMEPRTHPTWLLHIFIPFCIIAFIFIATV
Sbjct: 181 RLKPPPGRNFSCVFWNTHVRELTLASIDLQSQMEPRTHPTWLLHIFIPFCIIAFIFIATV 240

Query: 241 IALRKQLCQKLYSSKDTTKRPVTTTKREVNSAI 273
           IALRKQLCQKLYSSKDTTKRPVTTTKREVNSAI
Sbjct: 241 IALRKQLCQKLYSSKDTTKRPVTTTKREVNSAI 273


>gi|7661534 CD274 molecule [Homo sapiens]
          Length = 290

 Score =  150 bits (378), Expect = 1e-36
 Identities = 95/242 (39%), Positives = 131/242 (54%), Gaps = 27/242 (11%)

Query: 21  FTVTVPKELYIIEHGSNVTLECNFDTGSHVNLGAITASLQKVENDT-------------- 66
           FTVTVPK+LY++E+GSN+T+EC F     ++L A+    +  + +               
Sbjct: 19  FTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQH 78

Query: 67  SPHRERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKI 126
           S +R+RA LL++QL LG A+  I  V+++D G Y+C+I YG A DYK +T+KV A Y KI
Sbjct: 79  SSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGA-DYKRITVKVNAPYNKI 137

Query: 127 NTHILKV-PETDEVELTCQATGYPLAEVSWPN-----VSVPANTSHSRTPEGLYQVTSVL 180
           N  IL V P T E ELTCQA GYP AEV W +     +S    T++S+  E L+ VTS L
Sbjct: 138 NQRILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGKTTTTNSKREEKLFNVTSTL 197

Query: 181 RLKPPPGRNFSCVF-----WNTHVRELTLASIDLQSQMEPRTHPTWLLHIFIPFCI-IAF 234
           R+       F C F        H  EL +  + L      RTH   L  I +   + + F
Sbjct: 198 RINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNERTHLVILGAILLCLGVALTF 257

Query: 235 IF 236
           IF
Sbjct: 258 IF 259


>gi|67188443 CD276 antigen isoform a [Homo sapiens]
          Length = 534

 Score = 71.2 bits (173), Expect = 9e-13
 Identities = 71/256 (27%), Positives = 115/256 (44%), Gaps = 34/256 (13%)

Query: 23  VTVPKELYIIEHGSNVTLECNFDTGSHVNLGAI------TASLQKVENDT------SPHR 70
           V VP++  +   G++ TL C+F      +L  +      T + Q V + T      S + 
Sbjct: 249 VQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGRDQGSAYA 308

Query: 71  ERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIII---YGVAWDYKYLTLKVKASYRKIN 127
            R  L  + L  G AS  + +V+V DEG + C +    +G A     ++L+V A Y K +
Sbjct: 309 NRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSA----AVSLQVAAPYSKPS 364

Query: 128 THI---LKVPETDEVELTCQA-TGYPLAEVSWPN-VSVP----ANTSHSRTPEGLYQVTS 178
             +     +   D V +TC +  GYP AEV W +   VP      TS     +GL+ V S
Sbjct: 365 MTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHS 424

Query: 179 VLRLKPPPGRNFSCVFWNTHVRELTLASIDLQSQMEPRTHPTWLLHIFI--PFCIIAFIF 236
           VLR+       +SC+  N  +++    S+ +  Q  P T P   L + +    C+IA + 
Sbjct: 425 VLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQ--PMTFPPEALWVTVGLSVCLIALLV 482

Query: 237 IATVIALR--KQLCQK 250
               +  R  KQ C++
Sbjct: 483 ALAFVCWRKIKQSCEE 498



 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 59/230 (25%), Positives = 103/230 (44%), Gaps = 32/230 (13%)

Query: 23  VTVPKELYIIEHGSNVTLECNFDTGSHVNLGAITA------------SLQKVENDTSPHR 70
           V VP++  +   G++ TL C+F      +L  +              S  + ++  S + 
Sbjct: 31  VQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQGSAYA 90

Query: 71  ERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIII---YGVAWDYKYLTLKVKASYRKIN 127
            R  L  + L  G AS  + +V+V DEG + C +    +G A     ++L+V A Y K +
Sbjct: 91  NRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSA----AVSLQVAAPYSKPS 146

Query: 128 THI---LKVPETDEVELTCQA-TGYPLAEVSWPN-VSVP----ANTSHSRTPEGLYQVTS 178
             +     +   D V +TC +  GYP AEV W +   VP      TS     +GL+ V S
Sbjct: 147 MTLEPNKDLRPGDTVTITCSSYQGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHS 206

Query: 179 VLRLKPPPGRNFSCVFWNTHVRELTLASIDLQSQMEPRTHPTWLLHIFIP 228
           +LR+       +SC+  N  +++   +S+ +     P+  PT  + + +P
Sbjct: 207 ILRVVLGANGTYSCLVRNPVLQQDAHSSVTI----TPQRSPTGAVEVQVP 252


>gi|34932496 butyrophilin, subfamily 3, member A2 precursor [Homo
           sapiens]
          Length = 334

 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 73/299 (24%), Positives = 131/299 (43%), Gaps = 31/299 (10%)

Query: 1   MIFLLLMLSLELQLHQI----AALFTVTVPKELYIIEHGSNVTLECN-FDTGSH--VNLG 53
           + FLLL   + L L Q+    +A F+V  P    +   G +  L C+ F T S   + L 
Sbjct: 7   LAFLLLNFHVSLLLVQLLTPCSAQFSVLGPSGPILAMVGEDADLPCHLFPTMSAETMELK 66

Query: 54  AITASLQKVEN-----------DTSPHRERATLLEEQLPLGKASFHIPQVQVRDEGQYQC 102
            +++SL++V N            ++P+R R ++L + +  GKA+  I  V   D G+Y C
Sbjct: 67  WVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLC 126

Query: 103 IIIYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATG-YPLAEVSWPNV--- 158
               G  ++   + LKV A    ++  + K  E   + L C++TG YP  ++ W N    
Sbjct: 127 YFQDGDFYEKALVELKVAALGSNLHVEV-KGYEDGGIHLECRSTGWYPQPQIQWSNAKGE 185

Query: 159 SVPA-NTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNTHVRELTLASIDLQSQMEPRT 217
           ++PA          GLY+V + + ++   G   SC+  N+ +     ASI +        
Sbjct: 186 NIPAVEAPVVADGVGLYEVAASVIMRGGSGEGVSCIIRNSLLGLEKTASISIADPFFRSA 245

Query: 218 HPTWLLHIFIPFCIIAFIFIATVIALRKQ------LCQKLYSSKDTTKRPVTTTKREVN 270
            P W+  +     I+  +       L +Q      L  ++ S ++  +     T+RE++
Sbjct: 246 QP-WIAALAGTLPILLLLLAGASYFLWRQQKEITALSSEIESEQEMKEMGYAATEREIS 303


>gi|166197658 butyrophilin, subfamily 1, member A1 [Homo sapiens]
          Length = 526

 Score = 70.1 bits (170), Expect = 2e-12
 Identities = 67/285 (23%), Positives = 124/285 (43%), Gaps = 29/285 (10%)

Query: 6   LMLSLELQLHQI-AALFTVTVPKELYIIEHGSNVTLECNFDTGSHVNLGAITASLQKVEN 64
           L+  + LQL ++ +A F V  P E  +   G +  L C     +      +    +KV  
Sbjct: 13  LLTLILLQLPKLDSAPFDVIGPPEPILAVVGEDAELPCRLSPNASAEHLELRWFRKKVSP 72

Query: 65  DTSPHRE--------------RATLLEEQLPLGKASFHIPQVQVRDEGQYQCIIIYGVAW 110
               HR+              RATL+++ +  G+ +  I  V+V D+G+Y C      ++
Sbjct: 73  AVLVHRDGREQEAEQMPEYRGRATLVQDGIAKGRVALRIRGVRVSDDGEYTCFFREDGSY 132

Query: 111 DYKYLTLKVKASYRKINTHI-LKVPETDEVELTCQATG-YPLAEVSWPNVSVP--ANTSH 166
           +   + LKV A     + HI ++V E  E+ L C + G YP  +V W         +TS 
Sbjct: 133 EEALVHLKVAA--LGSDPHISMQVQENGEICLECTSVGWYPEPQVQWRTSKGEKFPSTSE 190

Query: 167 SRTP--EGLYQVTSVLRLKPPPGRNFSCVFWNTHVRELTLASIDLQSQMEPRTHPTWLLH 224
           SR P  EGL+ V + + ++    +N SC   N  + +     I + +   PR  P W++ 
Sbjct: 191 SRNPDEEGLFTVAASVIIRDTSAKNVSCYIQNLLLGQEKKVEISIPASSLPRLTP-WIVA 249

Query: 225 IFIPFCIIAFIFIATVIALRKQLCQKLYSSKDTTKRPVTTTKREV 269
           + +   ++  + I ++         +LY+ +   +R   ++K  +
Sbjct: 250 VAVILMVLGLLTIGSIF-----FTWRLYNERPRERRNEFSSKERL 289


>gi|13376852 CD276 antigen isoform b [Homo sapiens]
          Length = 316

 Score = 69.7 bits (169), Expect = 3e-12
 Identities = 68/256 (26%), Positives = 113/256 (44%), Gaps = 34/256 (13%)

Query: 23  VTVPKELYIIEHGSNVTLECNFDTGSHVNLGAITA------------SLQKVENDTSPHR 70
           V VP++  +   G++ TL C+F      +L  +              S  + ++  S + 
Sbjct: 31  VQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFAEGQDQGSAYA 90

Query: 71  ERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIII---YGVAWDYKYLTLKVKASYRKIN 127
            R  L  + L  G AS  + +V+V DEG + C +    +G A     ++L+V A Y K +
Sbjct: 91  NRTALFPDLLAQGNASLRLQRVRVADEGSFTCFVSIRDFGSA----AVSLQVAAPYSKPS 146

Query: 128 THI---LKVPETDEVELTCQA-TGYPLAEVSWPN-VSVP----ANTSHSRTPEGLYQVTS 178
             +     +   D V +TC +  GYP AEV W +   VP      TS     +GL+ V S
Sbjct: 147 MTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQGVPLTGNVTTSQMANEQGLFDVHS 206

Query: 179 VLRLKPPPGRNFSCVFWNTHVRELTLASIDLQSQMEPRTHPTWLLHIFI--PFCIIAFIF 236
           VLR+       +SC+  N  +++    S+ +  Q  P T P   L + +    C+IA + 
Sbjct: 207 VLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQ--PMTFPPEALWVTVGLSVCLIALLV 264

Query: 237 IATVIALR--KQLCQK 250
               +  R  KQ C++
Sbjct: 265 ALAFVCWRKIKQSCEE 280


>gi|5901908 butyrophilin, subfamily 3, member A3 isoform a [Homo
           sapiens]
          Length = 584

 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 70/282 (24%), Positives = 124/282 (43%), Gaps = 25/282 (8%)

Query: 1   MIFLLLMLSLELQLHQI----AALFTVTVPKELYIIEHGSNVTLECN-FDTGSH--VNLG 53
           + FLLL   + L L Q+    +A F+V  P    +   G +  L C+ F T S   + L 
Sbjct: 7   LAFLLLNFHVSLFLVQLLTPCSAQFSVLGPSGPILAMVGEDADLPCHLFPTMSAETMELR 66

Query: 54  AITASLQKVEN-----------DTSPHRERATLLEEQLPLGKASFHIPQVQVRDEGQYQC 102
            +++SL++V N            ++P+R R ++L + +  GKA+  I  V   D G+Y C
Sbjct: 67  WVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLC 126

Query: 103 IIIYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATG-YPLAEVSWPNV--- 158
               G  ++   + LKV A    ++  + K  E   + L C++TG YP  ++ W +    
Sbjct: 127 YFQDGDFYEKALVELKVAALGSDLHIEV-KGYEDGGIHLECRSTGWYPQPQIKWSDTKGE 185

Query: 159 SVPA-NTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNTHVRELTLASIDLQSQMEPRT 217
           ++PA          GLY V + + ++   G   SC+  N+ +     ASI +        
Sbjct: 186 NIPAVEAPVVADGVGLYAVAASVIMRGSSGGGVSCIIRNSLLGLEKTASISIADPFFRSA 245

Query: 218 HPTWLLHIFIPFCIIAFIFIATVIALRKQLCQKLYSSKDTTK 259
            P W+  +     I   +       L +Q  +K+  S++T +
Sbjct: 246 QP-WIAALAGTLPISLLLLAGASYFLWRQQKEKIALSRETER 286


>gi|37574628 butyrophilin, subfamily 3, member A3 isoform b [Homo
           sapiens]
          Length = 542

 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 54/227 (23%), Positives = 102/227 (44%), Gaps = 8/227 (3%)

Query: 39  TLECNFDTGSHVNLGAITASLQKVEN-DTSPHRERATLLEEQLPLGKASFHIPQVQVRDE 97
           T+E  + + S   +  + A  ++VE+  ++P+R R ++L + +  GKA+  I  V   D 
Sbjct: 20  TMELRWVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDS 79

Query: 98  GQYQCIIIYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATG-YPLAEVSWP 156
           G+Y C    G  ++   + LKV A    ++  + K  E   + L C++TG YP  ++ W 
Sbjct: 80  GKYLCYFQDGDFYEKALVELKVAALGSDLHIEV-KGYEDGGIHLECRSTGWYPQPQIKWS 138

Query: 157 NV---SVPA-NTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNTHVRELTLASIDLQSQ 212
           +    ++PA          GLY V + + ++   G   SC+  N+ +     ASI +   
Sbjct: 139 DTKGENIPAVEAPVVADGVGLYAVAASVIMRGSSGGGVSCIIRNSLLGLEKTASISIADP 198

Query: 213 MEPRTHPTWLLHIFIPFCIIAFIFIATVIALRKQLCQKLYSSKDTTK 259
                 P W+  +     I   +       L +Q  +K+  S++T +
Sbjct: 199 FFRSAQP-WIAALAGTLPISLLLLAGASYFLWRQQKEKIALSRETER 244


>gi|37221189 butyrophilin, subfamily 3, member A1 isoform b [Homo
           sapiens]
          Length = 352

 Score = 58.9 bits (141), Expect = 5e-09
 Identities = 61/233 (26%), Positives = 105/233 (45%), Gaps = 26/233 (11%)

Query: 1   MIFLLLMLSLELQLHQI----AALFTVTVPKELYIIEHGSNVTLECN-FDTGSH--VNLG 53
           + FLLL   + L L Q+    +A F+V  P    +   G +  L C+ F T S   + L 
Sbjct: 7   LAFLLLNFRVCLLLLQLLMPHSAQFSVLGPSGPILAMVGEDADLPCHLFPTMSAETMELK 66

Query: 54  AITASLQKVEN-----------DTSPHRERATLLEEQLPLGKASFHIPQVQVRDEGQYQC 102
            +++SL++V N            ++P+R R ++L + +  GKA+  I  V   D G+Y C
Sbjct: 67  WVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLC 126

Query: 103 IIIYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATG-YPLAEVSWPNVSVP 161
               G  ++   + LKV A    ++  + K  +   + L C++TG YP  ++ W N +  
Sbjct: 127 YFQDGDFYEKALVELKVAALGSDLHVDV-KGYKDGGIHLECRSTGWYPQPQIQWSN-NKG 184

Query: 162 ANTSHSRTP-----EGLYQVTSVLRLKPPPGRNFSCVFWNTHVRELTLASIDL 209
            N      P      GLY V + + ++   G   SC   ++ +     ASI +
Sbjct: 185 ENIPTVEAPVVADGVGLYAVAASVIMRGSSGEGVSCTIRSSLLGLEKTASISI 237


>gi|222418660 butyrophilin, subfamily 3, member A1 isoform d [Homo
           sapiens]
          Length = 378

 Score = 58.9 bits (141), Expect = 5e-09
 Identities = 61/233 (26%), Positives = 105/233 (45%), Gaps = 26/233 (11%)

Query: 1   MIFLLLMLSLELQLHQI----AALFTVTVPKELYIIEHGSNVTLECN-FDTGSH--VNLG 53
           + FLLL   + L L Q+    +A F+V  P    +   G +  L C+ F T S   + L 
Sbjct: 7   LAFLLLNFRVCLLLLQLLMPHSAQFSVLGPSGPILAMVGEDADLPCHLFPTMSAETMELK 66

Query: 54  AITASLQKVEN-----------DTSPHRERATLLEEQLPLGKASFHIPQVQVRDEGQYQC 102
            +++SL++V N            ++P+R R ++L + +  GKA+  I  V   D G+Y C
Sbjct: 67  WVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLC 126

Query: 103 IIIYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATG-YPLAEVSWPNVSVP 161
               G  ++   + LKV A    ++  + K  +   + L C++TG YP  ++ W N +  
Sbjct: 127 YFQDGDFYEKALVELKVAALGSDLHVDV-KGYKDGGIHLECRSTGWYPQPQIQWSN-NKG 184

Query: 162 ANTSHSRTP-----EGLYQVTSVLRLKPPPGRNFSCVFWNTHVRELTLASIDL 209
            N      P      GLY V + + ++   G   SC   ++ +     ASI +
Sbjct: 185 ENIPTVEAPVVADGVGLYAVAASVIMRGSSGEGVSCTIRSSLLGLEKTASISI 237


>gi|37595558 butyrophilin, subfamily 3, member A1 isoform a [Homo
           sapiens]
          Length = 513

 Score = 58.9 bits (141), Expect = 5e-09
 Identities = 61/233 (26%), Positives = 105/233 (45%), Gaps = 26/233 (11%)

Query: 1   MIFLLLMLSLELQLHQI----AALFTVTVPKELYIIEHGSNVTLECN-FDTGSH--VNLG 53
           + FLLL   + L L Q+    +A F+V  P    +   G +  L C+ F T S   + L 
Sbjct: 7   LAFLLLNFRVCLLLLQLLMPHSAQFSVLGPSGPILAMVGEDADLPCHLFPTMSAETMELK 66

Query: 54  AITASLQKVEN-----------DTSPHRERATLLEEQLPLGKASFHIPQVQVRDEGQYQC 102
            +++SL++V N            ++P+R R ++L + +  GKA+  I  V   D G+Y C
Sbjct: 67  WVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLC 126

Query: 103 IIIYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATG-YPLAEVSWPNVSVP 161
               G  ++   + LKV A    ++  + K  +   + L C++TG YP  ++ W N +  
Sbjct: 127 YFQDGDFYEKALVELKVAALGSDLHVDV-KGYKDGGIHLECRSTGWYPQPQIQWSN-NKG 184

Query: 162 ANTSHSRTP-----EGLYQVTSVLRLKPPPGRNFSCVFWNTHVRELTLASIDL 209
            N      P      GLY V + + ++   G   SC   ++ +     ASI +
Sbjct: 185 ENIPTVEAPVVADGVGLYAVAASVIMRGSSGEGVSCTIRSSLLGLEKTASISI 237


>gi|6453813 butyrophilin, subfamily 2, member A2 isoform a [Homo
           sapiens]
          Length = 523

 Score = 53.9 bits (128), Expect = 1e-07
 Identities = 62/260 (23%), Positives = 101/260 (38%), Gaps = 24/260 (9%)

Query: 1   MIFLLLMLSLELQLHQIAALFTVTVPKELYIIEHGSNVTLECNFDTGSHVN--------- 51
           ++ LLL+LSL      ++A FTV  P    +   G N TL C+     +           
Sbjct: 17  LLLLLLLLSL---CALVSAQFTVVGPANPILAMVGENTTLRCHLSPEKNAEDMEVRWFRS 73

Query: 52  -----LGAITASLQKVENDTSPHRERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIIIY 106
                +       ++ E     +R R T + + +  G  +  I  V  ++ G Y+C    
Sbjct: 74  QFSPAVFVYKGGRERTEEQMEEYRGRITFVSKDINRGSVALVIHNVTAQENGIYRCYFQE 133

Query: 107 GVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATG-YPLAEVSWPN---VSVPA 162
           G ++D   L L V     K    I K  E   + L C + G YP     W +     VPA
Sbjct: 134 GRSYDEAILRLVVAGLGSKPLIEI-KAQEDGSIWLECISGGWYPEPLTVWRDPYGEVVPA 192

Query: 163 NTSHS-RTPEGLYQVTSVLRLKPPPGRNFSCVFWNTHVRELTLASIDLQSQMEPRTHPTW 221
               S    +GL+ VT+ + ++    RN SC   NT + +     I +     P   P W
Sbjct: 193 LKEVSIADADGLFMVTTAVIIRDKYVRNVSCSVNNTLLGQEKETVIFIPESFMPSASP-W 251

Query: 222 LLHIFIPFCIIAFIFIATVI 241
           ++ + +      ++   TVI
Sbjct: 252 MVALAVILTASPWMVSMTVI 271


>gi|27477039 inducible T-cell co-stimulator ligand [Homo sapiens]
          Length = 302

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 53/201 (26%), Positives = 80/201 (39%), Gaps = 29/201 (14%)

Query: 35  GSNVTLECNFDTGSHVNLGAITASLQ----------------KVENDTSPHRERATLLEE 78
           GS+V L C    GS  +L  +    Q                 +EN  S +R RA +   
Sbjct: 30  GSDVELSCACPEGSRFDLNDVYVYWQTSESKTVVTYHIPQNSSLENVDSRYRNRALMSPA 89

Query: 79  QLPLGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYL----TLKVKASYRKINTHILKVP 134
            +  G  S  +  V  +DE ++ C+++       + L    TL V A++          P
Sbjct: 90  GMLRGDFSLRLFNVTPQDEQKFHCLVLSQSLGFQEVLSVEVTLHVAANFSVPVVSAPHSP 149

Query: 135 ETDEVELTCQA-TGYPLAEVSWPNVSVPA-------NTSHSRTPEGLYQVTSVLRLKPPP 186
             DE+  TC +  GYP   V W N +  +       N +      GLY V SVLR+   P
Sbjct: 150 SQDELTFTCTSINGYPRPNVYWINKTDNSLLDQALQNDTVFLNMRGLYDVVSVLRIARTP 209

Query: 187 GRNFSCVFWNTHVRE-LTLAS 206
             N  C   N  +++ LT+ S
Sbjct: 210 SVNIGCCIENVLLQQNLTVGS 230


>gi|5921461 butyrophilin, subfamily 2, member A1 isoform 1 precursor
           [Homo sapiens]
          Length = 527

 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 57/264 (21%), Positives = 97/264 (36%), Gaps = 33/264 (12%)

Query: 4   LLLMLSLELQLHQIAALFTVTVPKELYIIEHGSNVTLECNFDTGSHVN------------ 51
           LLL+LSL      ++A F V  P +  +   G N TL C+     +              
Sbjct: 16  LLLLLSL---CALVSAQFIVVGPTDPILATVGENTTLRCHLSPEKNAEDMEVRWFRSQFS 72

Query: 52  --LGAITASLQKVENDTSPHRERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIIIYGVA 109
             +       ++ E     +R R T + + +  G  +  I  +  ++ G Y+C    G +
Sbjct: 73  PAVFVYKGGRERTEEQMEEYRGRTTFVSKDISRGSVALVIHNITAQENGTYRCYFQEGRS 132

Query: 110 WDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATG-YPLAEVSW--PNVSVPANTSH 166
           +D   L L V     K     ++  E   + L C + G YP     W  P   V      
Sbjct: 133 YDEAILHLVVAGLGSKPLIS-MRGHEDGGIRLECISRGWYPKPLTVWRDPYGGVAPALKE 191

Query: 167 SRTPE--GLYQVTSVLRLKPPPGRNFSCVFWNTHVRELTLASIDLQSQMEPRTHPTWLLH 224
              P+  GL+ VT+ + ++    RN SC   NT + +   + I +     P   P     
Sbjct: 192 VSMPDADGLFMVTTAVIIRDKSVRNMSCSINNTLLGQKKESVIFIPESFMPSVSP----- 246

Query: 225 IFIPFCIIAFIFIATVIALRKQLC 248
                C +A   I  ++ +   +C
Sbjct: 247 -----CAVALPIIVVILMIPIAVC 265


>gi|17975772 butyrophilin, subfamily 2, member A1 isoform 2
           precursor [Homo sapiens]
          Length = 334

 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 57/264 (21%), Positives = 97/264 (36%), Gaps = 33/264 (12%)

Query: 4   LLLMLSLELQLHQIAALFTVTVPKELYIIEHGSNVTLECNFDTGSHVN------------ 51
           LLL+LSL      ++A F V  P +  +   G N TL C+     +              
Sbjct: 16  LLLLLSL---CALVSAQFIVVGPTDPILATVGENTTLRCHLSPEKNAEDMEVRWFRSQFS 72

Query: 52  --LGAITASLQKVENDTSPHRERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIIIYGVA 109
             +       ++ E     +R R T + + +  G  +  I  +  ++ G Y+C    G +
Sbjct: 73  PAVFVYKGGRERTEEQMEEYRGRTTFVSKDISRGSVALVIHNITAQENGTYRCYFQEGRS 132

Query: 110 WDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATG-YPLAEVSW--PNVSVPANTSH 166
           +D   L L V     K     ++  E   + L C + G YP     W  P   V      
Sbjct: 133 YDEAILHLVVAGLGSKPLIS-MRGHEDGGIRLECISRGWYPKPLTVWRDPYGGVAPALKE 191

Query: 167 SRTPE--GLYQVTSVLRLKPPPGRNFSCVFWNTHVRELTLASIDLQSQMEPRTHPTWLLH 224
              P+  GL+ VT+ + ++    RN SC   NT + +   + I +     P   P     
Sbjct: 192 VSMPDADGLFMVTTAVIIRDKSVRNMSCSINNTLLGQKKESVIFIPESFMPSVSP----- 246

Query: 225 IFIPFCIIAFIFIATVIALRKQLC 248
                C +A   I  ++ +   +C
Sbjct: 247 -----CAVALPIIVVILMIPIAVC 265


>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
           [Homo sapiens]
          Length = 1093

 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 9/97 (9%)

Query: 62  VENDTSPHRERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIII--YGVAWDYKY-LTLK 118
           +EN    H +   ++E    L     H+ QV    EG+YQC+I   +G  + +K  LT+ 
Sbjct: 542 MENFVHVHAQDGEVMEYTTIL-----HLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVN 596

Query: 119 VKASYRKINTHILKVPETDEVELTCQATGYPLAEVSW 155
           V  S+ K   H + +  T    L C ATG+P  +++W
Sbjct: 597 VLPSFTK-TPHDITIRTTTMARLECAATGHPNPQIAW 632



 Score = 33.1 bits (74), Expect = 0.27
 Identities = 30/120 (25%), Positives = 46/120 (38%), Gaps = 17/120 (14%)

Query: 87  FHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINTHILKVPETDEV------- 139
           F I  V++ D G Y C             ++   A+   + T  L VP  D V       
Sbjct: 657 FFITDVKIDDAGVYSCTAQNSAG------SISANATLTVLETPSLVVPLEDRVVSVGETV 710

Query: 140 ELTCQATGYPLAEVSWPNVSVPANTS--HSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNT 197
            L C+ATG P   ++W     P + +  H  TP+   Q+  V  +       ++C   NT
Sbjct: 711 ALQCKATGNPPPRITWFKGDRPLSLTERHHLTPDN--QLLVVQNVVAEDAGRYTCEMSNT 768


>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3874

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 30/117 (25%), Positives = 48/117 (41%), Gaps = 2/117 (1%)

Query: 83   GKASFHIPQVQVRDEGQYQCII--IYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVE 140
            G     I + QV D+G Y C +  + G A     LT++V  ++    T  +       + 
Sbjct: 1893 GGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLV 1952

Query: 141  LTCQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNT 197
            LTC  +G P   V+W    +P  +S             + RL+P     ++CV  NT
Sbjct: 1953 LTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENT 2009



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 30/96 (31%), Positives = 42/96 (43%), Gaps = 5/96 (5%)

Query: 72   RATLLEEQLPLGKASFHIPQVQVRDEGQYQCIII--YGVAWDYKYLTLKVKASYRKINTH 129
            R + L  QL  G  + H  + +  D G+YQC+     GVA     L L+  A   ++   
Sbjct: 3069 RGSHLRHQLQNGSLTIH--RTERDDAGRYQCLAENEMGVAKKVVILVLQ-SAPVFQVEPQ 3125

Query: 130  ILKVPETDEVELTCQATGYPLAEVSWPNVSVPANTS 165
             + V   D+V L CQATG P   + W     P   S
Sbjct: 3126 DMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRAS 3161



 Score = 37.0 bits (84), Expect = 0.018
 Identities = 28/105 (26%), Positives = 42/105 (40%), Gaps = 6/105 (5%)

Query: 80   LPLGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKAS--YRKINTHILKVPETD 137
            L   KA   + +  V D G Y C  +       K+  L V  +  +    +H L V E  
Sbjct: 928  LSADKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLNVWVAPVFPLRESHTLTVREGH 987

Query: 138  EVELTCQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRL 182
               L+C+  G P  ++SW     P     +    GL  V++V RL
Sbjct: 988  PTSLSCECRGVPFPKISWRKDGQPLPGEGA----GLQHVSAVGRL 1028



 Score = 34.7 bits (78), Expect = 0.092
 Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 3/65 (4%)

Query: 94  VRDEGQYQCIIIYGVAWDYKYLTLKVKAS---YRKINTHILKVPETDEVELTCQATGYPL 150
           V DEG+YQC+         +   L+V A    +    T  + V E   V+L C+A G P 
Sbjct: 281 VGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPT 340

Query: 151 AEVSW 155
             ++W
Sbjct: 341 PNITW 345



 Score = 34.7 bits (78), Expect = 0.092
 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 8/104 (7%)

Query: 98   GQYQCII--IYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATGYPLAEVSW 155
            G+Y C      GVA  + +LT++     + + + +  V E +EV L C+A+G P   ++W
Sbjct: 2732 GRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAE-EEVLLPCEASGIPRPTITW 2790

Query: 156  --PNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNT 197
                ++V    S    P G  ++       P    N+ C+  N+
Sbjct: 2791 QKEGLNVATGVSTQVLPGGQLRIA---HASPEDAGNYLCIAKNS 2831



 Score = 33.5 bits (75), Expect = 0.20
 Identities = 40/148 (27%), Positives = 57/148 (38%), Gaps = 12/148 (8%)

Query: 88   HIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVK-----ASYRKINTHILKVPETDEVELT 142
            ++ Q Q+  EG Y C     V    + L L+V      A  R+  T +  V +     L 
Sbjct: 1030 YLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQV-SVVQDGVATLE 1088

Query: 143  CQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNTHVR-- 200
            C ATG P   V+W     P         +   Q   V R +      +SCV  N   R  
Sbjct: 1089 CNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAE 1148

Query: 201  ---ELT-LASIDLQSQMEPRTHPTWLLH 224
               EL+ L   +L   ++P T+ T  LH
Sbjct: 1149 RKFELSVLVPPELIGDLDPLTNITAALH 1176



 Score = 33.1 bits (74), Expect = 0.27
 Identities = 25/111 (22%), Positives = 47/111 (42%), Gaps = 7/111 (6%)

Query: 91   QVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINT---HILKVPETDEVELTCQATG 147
            Q Q +D G Y C+         +  +++V       N     ++KV +     L C  TG
Sbjct: 1221 QTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTG 1280

Query: 148  YPLAEVSWPNVSVP--ANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWN 196
            +P  +++W     P     +H  +P+G+  +  VL+       ++SC+  N
Sbjct: 1281 HPQPKLTWFKDGRPLARGDAHHISPDGV--LLQVLQANLSSAGHYSCIAAN 1329



 Score = 31.6 bits (70), Expect = 0.78
 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 7/71 (9%)

Query: 89  IPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYR----KINTHILKVPETDEVELTCQ 144
           I +V +RDEG Y C          + + LKV          +N  +L   E   V L C 
Sbjct: 661 IEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVL---ENASVTLECL 717

Query: 145 ATGYPLAEVSW 155
           A+G P  +VSW
Sbjct: 718 ASGVPPPDVSW 728



 Score = 30.8 bits (68), Expect = 1.3
 Identities = 23/95 (24%), Positives = 43/95 (45%), Gaps = 13/95 (13%)

Query: 74   TLLEEQLPLGKASFH----------IPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASY 123
            T L++++P+  ++ H          + ++Q    G Y C+     A   K   + V  + 
Sbjct: 1966 TWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAP 2025

Query: 124  RKINTHILK---VPETDEVELTCQATGYPLAEVSW 155
            R  ++ + +   V E  EV L C+A G P  +V+W
Sbjct: 2026 RIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAW 2060



 Score = 30.0 bits (66), Expect = 2.3
 Identities = 37/123 (30%), Positives = 50/123 (40%), Gaps = 19/123 (15%)

Query: 79  QLPLGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINT----HILKVP 134
           QL LG+A       Q  D G Y C     V    K   L V             +++K  
Sbjct: 366 QLQLGRA-------QSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAV 418

Query: 135 ETDEVELTCQATGYPLAEVSWPNVSVP-ANTSHSRTPEGLYQVTSVLRLKPPPGRN---F 190
               V L C A G+P   +SW +  +P A ++ SR    L    SVLRL+ P   +   +
Sbjct: 419 AGRPVALECVARGHPSPTLSWHHEGLPVAESNESR----LETDGSVLRLESPGEASSGLY 474

Query: 191 SCV 193
           SCV
Sbjct: 475 SCV 477



 Score = 30.0 bits (66), Expect = 2.3
 Identities = 16/68 (23%), Positives = 30/68 (44%), Gaps = 1/68 (1%)

Query: 89  IPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINTHI-LKVPETDEVELTCQATG 147
           +   +  D G+Y C+ +  V  D + + L+V      +   + + V   + V L CQ+  
Sbjct: 846 LASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHA 905

Query: 148 YPLAEVSW 155
            P   +SW
Sbjct: 906 MPPPVLSW 913



 Score = 30.0 bits (66), Expect = 2.3
 Identities = 29/119 (24%), Positives = 44/119 (36%), Gaps = 5/119 (4%)

Query: 83   GKASFHIPQVQVRDEGQYQCIIIYGVAWDYKY-----LTLKVKASYRKINTHILKVPETD 137
            G     IP V+  + G+Y C     V  D+ +     LT  V     +     + V  + 
Sbjct: 1611 GGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASS 1670

Query: 138  EVELTCQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWN 196
             V L C A G P+  +SW    +P + S         QV  V   +     ++ CV  N
Sbjct: 1671 TVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAEN 1729



 Score = 29.6 bits (65), Expect = 3.0
 Identities = 35/134 (26%), Positives = 48/134 (35%), Gaps = 19/134 (14%)

Query: 62   VENDTSP----HRERATLLEE---QLPLGKASFHIPQVQVRDEGQYQCII-----IYGVA 109
            VE + +P    HR+   L E+   Q P       +  +   D G Y C          VA
Sbjct: 2414 VEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVA 2473

Query: 110  WDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATGYPLAEVSWPNVSVPANTSHSR- 168
            +  +  T+    S        + V       L CQA G P   VSW    VP +    R 
Sbjct: 2474 FRVEIHTVPTIRS----GPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRF 2529

Query: 169  --TPEGLYQVTSVL 180
               PEG  ++  VL
Sbjct: 2530 EILPEGSLRIQPVL 2543



 Score = 29.3 bits (64), Expect = 3.9
 Identities = 32/110 (29%), Positives = 40/110 (36%), Gaps = 6/110 (5%)

Query: 89  IPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINTHILKVPE--TDEVELTCQAT 146
           I Q Q+ D G Y+C+             L+V    R      L  P      V LTC AT
Sbjct: 752 IEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNAT 811

Query: 147 GYPLAEVSW---PNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCV 193
           G P   + W    N   PA T   +   G   +T         GR +SCV
Sbjct: 812 GAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGR-YSCV 860



 Score = 29.3 bits (64), Expect = 3.9
 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 3/73 (4%)

Query: 86   SFHIPQVQVRDEGQYQCIIIY--GVAWDYKYLTLKVKASYRKIN-THILKVPETDEVELT 142
            +  I +VQ+ D G + C+     GVA     L ++V      +   + + V     VEL 
Sbjct: 2177 TLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELP 2236

Query: 143  CQATGYPLAEVSW 155
            C+A G PL  VSW
Sbjct: 2237 CEARGVPLPLVSW 2249



 Score = 28.9 bits (63), Expect = 5.0
 Identities = 23/120 (19%), Positives = 41/120 (34%), Gaps = 16/120 (13%)

Query: 64   NDTSPHRERATLLEEQLPLGKASFH----------IPQVQVRDEGQYQCIIIYGVAWDYK 113
            N T   + + T  ++  PL +   H          + Q  +   G Y CI    V    K
Sbjct: 1277 NVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTK 1336

Query: 114  YLTLKVKASYRKIN------THILKVPETDEVELTCQATGYPLAEVSWPNVSVPANTSHS 167
            +  L V  +   +          + V   + + L C+A  +P   ++W     P   S +
Sbjct: 1337 HFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRN 1396



 Score = 28.5 bits (62), Expect = 6.6
 Identities = 22/91 (24%), Positives = 36/91 (39%), Gaps = 6/91 (6%)

Query: 95   RDEGQYQCIII--YGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATGYPLAE 152
            +D  Q++C++    G A     +T+ V  +     T    V     V LTC +TG P   
Sbjct: 2638 QDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFT-VTMMAPVVLTCHSTGIPAPT 2696

Query: 153  VSWPNVSV---PANTSHSRTPEGLYQVTSVL 180
            VSW           + +  +P G  ++   L
Sbjct: 2697 VSWSKAGAQLGARGSGYRVSPSGALEIGQAL 2727



 Score = 28.1 bits (61), Expect = 8.6
 Identities = 19/80 (23%), Positives = 31/80 (38%), Gaps = 9/80 (11%)

Query: 82  LGKASFHIPQVQVRDEGQYQCIIIYGVAWDYK------YLTLKVKASYRKINTHILKVPE 135
           L + S  +  V   D G Y+C     V    +      Y+   ++   RK N   +    
Sbjct: 54  LEEGSLFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMA--- 110

Query: 136 TDEVELTCQATGYPLAEVSW 155
              + L C A G+P+ E+ W
Sbjct: 111 GQSLTLECDANGFPVPEIVW 130


>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 5065

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 30/117 (25%), Positives = 48/117 (41%), Gaps = 2/117 (1%)

Query: 83   GKASFHIPQVQVRDEGQYQCII--IYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVE 140
            G     I + QV D+G Y C +  + G A     LT++V  ++    T  +       + 
Sbjct: 3084 GGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLV 3143

Query: 141  LTCQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNT 197
            LTC  +G P   V+W    +P  +S             + RL+P     ++CV  NT
Sbjct: 3144 LTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENT 3200



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 30/96 (31%), Positives = 42/96 (43%), Gaps = 5/96 (5%)

Query: 72   RATLLEEQLPLGKASFHIPQVQVRDEGQYQCIII--YGVAWDYKYLTLKVKASYRKINTH 129
            R + L  QL  G  + H  + +  D G+YQC+     GVA     L L+  A   ++   
Sbjct: 4260 RGSHLRHQLQNGSLTIH--RTERDDAGRYQCLAENEMGVAKKVVILVLQ-SAPVFQVEPQ 4316

Query: 130  ILKVPETDEVELTCQATGYPLAEVSWPNVSVPANTS 165
             + V   D+V L CQATG P   + W     P   S
Sbjct: 4317 DMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRAS 4352



 Score = 38.1 bits (87), Expect = 0.008
 Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 4/113 (3%)

Query: 82  LGKASFHIPQVQVRDEGQYQCII--IYGVAWDYKYLTLKVKASYRKINTHILKVPETDEV 139
           L   S  I  +   D G+YQC+     GV     +L ++ +A    I+T      +  EV
Sbjct: 567 LADLSLEISGIIPTDGGRYQCVASNANGVTRASVWLLVR-EAPQVSIHTSSQHFSQGVEV 625

Query: 140 ELTCQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSC 192
           +++C A+GYP   +SW   S  A    SR          +  + P    N+SC
Sbjct: 626 KVSCSASGYPTPHISWSRES-QALQEDSRIHVDAQGTLIIQGVAPEDAGNYSC 677



 Score = 37.7 bits (86), Expect = 0.011
 Identities = 37/132 (28%), Positives = 54/132 (40%), Gaps = 8/132 (6%)

Query: 45   DTGSHVNLGAITASLQKVENDTSPHRERAT--LLEEQLPLGKASFHIPQVQVRDEGQYQC 102
            D G++V     T      E   S +R   +  + EE   L   S  + QVQV D G Y+C
Sbjct: 1040 DAGAYVCTATNTVGFSSQEMRLSVNRLALSKYVWEEYGLLPSGSLRLAQVQVGDSGHYEC 1099

Query: 103  III--YGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATGYPLAEVSWPNVSV 160
                  G A     L ++V    +     +LKV   + ++L C A G P  ++SW    V
Sbjct: 1100 TASNPAGSASHRYVLGVQVPPQVQP-GPRVLKVLVGEALDLNCVAEGNPEPQLSWSKDGV 1158

Query: 161  PANTSHSRTPEG 172
                   R P+G
Sbjct: 1159 ---VLQGRGPQG 1167



 Score = 37.4 bits (85), Expect = 0.014
 Identities = 28/105 (26%), Positives = 42/105 (40%), Gaps = 6/105 (5%)

Query: 80   LPLGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKAS--YRKINTHILKVPETD 137
            L   KA   + +  V D G Y C  +       K+  L V  +  +    +H L V E  
Sbjct: 2119 LSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGH 2178

Query: 138  EVELTCQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRL 182
               L+C+  G P  ++SW     P     +    GL  V++V RL
Sbjct: 2179 PTSLSCECRGVPFPKISWRKDGQPLPGEGA----GLQHVSAVGRL 2219



 Score = 34.7 bits (78), Expect = 0.092
 Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 3/65 (4%)

Query: 94   VRDEGQYQCIIIYGVAWDYKYLTLKVKAS---YRKINTHILKVPETDEVELTCQATGYPL 150
            V DEG+YQC+         +   L+V A    +    T  + V E   V+L C+A G P 
Sbjct: 1472 VGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPT 1531

Query: 151  AEVSW 155
              ++W
Sbjct: 1532 PNITW 1536



 Score = 34.7 bits (78), Expect = 0.092
 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 8/104 (7%)

Query: 98   GQYQCII--IYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATGYPLAEVSW 155
            G+Y C      GVA  + +LT++     + + + +  V E +EV L C+A+G P   ++W
Sbjct: 3923 GRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAE-EEVLLPCEASGIPRPTITW 3981

Query: 156  --PNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNT 197
                ++V    S    P G  ++       P    N+ C+  N+
Sbjct: 3982 QKEGLNVATGVSTQVLPGGQLRIA---HASPEDAGNYLCIAKNS 4022



 Score = 33.5 bits (75), Expect = 0.20
 Identities = 40/148 (27%), Positives = 57/148 (38%), Gaps = 12/148 (8%)

Query: 88   HIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVK-----ASYRKINTHILKVPETDEVELT 142
            ++ Q Q+  EG Y C     V    + L L+V      A  R+  T +  V +     L 
Sbjct: 2221 YLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQV-SVVQDGVATLE 2279

Query: 143  CQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNTHVR-- 200
            C ATG P   V+W     P         +   Q   V R +      +SCV  N   R  
Sbjct: 2280 CNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAE 2339

Query: 201  ---ELT-LASIDLQSQMEPRTHPTWLLH 224
               EL+ L   +L   ++P T+ T  LH
Sbjct: 2340 RKFELSVLVPPELIGDLDPLTNITAALH 2367



 Score = 33.1 bits (74), Expect = 0.27
 Identities = 25/111 (22%), Positives = 47/111 (42%), Gaps = 7/111 (6%)

Query: 91   QVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINT---HILKVPETDEVELTCQATG 147
            Q Q +D G Y C+         +  +++V       N     ++KV +     L C  TG
Sbjct: 2412 QTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTG 2471

Query: 148  YPLAEVSWPNVSVP--ANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWN 196
            +P  +++W     P     +H  +P+G+  +  VL+       ++SC+  N
Sbjct: 2472 HPQPKLTWFKDGRPLARGDAHHISPDGV--LLQVLQANLSSAGHYSCIAAN 2520



 Score = 32.3 bits (72), Expect = 0.46
 Identities = 31/98 (31%), Positives = 43/98 (43%), Gaps = 8/98 (8%)

Query: 131 LKVPETDEVELTCQA-TGYPLAEVSW--PNVSVPANTSHSRTPEGLYQVTSVLRLKPPPG 187
           ++V E   V L C    G PL E  W      +P  + HS   +G   +   L+     G
Sbjct: 894 VRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDRALQ--EHAG 951

Query: 188 RNFSCVFWNTHVRELTLASIDLQSQMEPRTHPTWLLHI 225
           R +SCV  NT   +     ++L  Q+ PR HPT   HI
Sbjct: 952 R-YSCVATNTAGSQHR--DVELVVQVPPRIHPTATHHI 986



 Score = 31.6 bits (70), Expect = 0.78
 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 7/71 (9%)

Query: 89   IPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYR----KINTHILKVPETDEVELTCQ 144
            I +V +RDEG Y C          + + LKV          +N  +L   E   V L C 
Sbjct: 1852 IEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVL---ENASVTLECL 1908

Query: 145  ATGYPLAEVSW 155
            A+G P  +VSW
Sbjct: 1909 ASGVPPPDVSW 1919



 Score = 30.8 bits (68), Expect = 1.3
 Identities = 23/95 (24%), Positives = 43/95 (45%), Gaps = 13/95 (13%)

Query: 74   TLLEEQLPLGKASFH----------IPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASY 123
            T L++++P+  ++ H          + ++Q    G Y C+     A   K   + V  + 
Sbjct: 3157 TWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAP 3216

Query: 124  RKINTHILK---VPETDEVELTCQATGYPLAEVSW 155
            R  ++ + +   V E  EV L C+A G P  +V+W
Sbjct: 3217 RIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAW 3251



 Score = 30.0 bits (66), Expect = 2.3
 Identities = 37/123 (30%), Positives = 50/123 (40%), Gaps = 19/123 (15%)

Query: 79   QLPLGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINT----HILKVP 134
            QL LG+A       Q  D G Y C     V    K   L V             +++K  
Sbjct: 1557 QLQLGRA-------QSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAV 1609

Query: 135  ETDEVELTCQATGYPLAEVSWPNVSVP-ANTSHSRTPEGLYQVTSVLRLKPPPGRN---F 190
                V L C A G+P   +SW +  +P A ++ SR    L    SVLRL+ P   +   +
Sbjct: 1610 AGRPVALECVARGHPSPTLSWHHEGLPVAESNESR----LETDGSVLRLESPGEASSGLY 1665

Query: 191  SCV 193
            SCV
Sbjct: 1666 SCV 1668



 Score = 30.0 bits (66), Expect = 2.3
 Identities = 16/68 (23%), Positives = 30/68 (44%), Gaps = 1/68 (1%)

Query: 89   IPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINTHI-LKVPETDEVELTCQATG 147
            +   +  D G+Y C+ +  V  D + + L+V      +   + + V   + V L CQ+  
Sbjct: 2037 LASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHA 2096

Query: 148  YPLAEVSW 155
             P   +SW
Sbjct: 2097 MPPPVLSW 2104



 Score = 30.0 bits (66), Expect = 2.3
 Identities = 29/119 (24%), Positives = 44/119 (36%), Gaps = 5/119 (4%)

Query: 83   GKASFHIPQVQVRDEGQYQCIIIYGVAWDYKY-----LTLKVKASYRKINTHILKVPETD 137
            G     IP V+  + G+Y C     V  D+ +     LT  V     +     + V  + 
Sbjct: 2802 GGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASS 2861

Query: 138  EVELTCQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWN 196
             V L C A G P+  +SW    +P + S         QV  V   +     ++ CV  N
Sbjct: 2862 TVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAEN 2920



 Score = 29.6 bits (65), Expect = 3.0
 Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 3/69 (4%)

Query: 89  IPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVK--ASYRKINTHILKVPETDEVELTCQAT 146
           I  V   D G Y C     V  D + +TL      S   +N  +L V   +E  L C+A+
Sbjct: 664 IQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVL-VAVGEEAVLVCEAS 722

Query: 147 GYPLAEVSW 155
           G P   V W
Sbjct: 723 GVPPPRVIW 731



 Score = 29.6 bits (65), Expect = 3.0
 Identities = 35/134 (26%), Positives = 48/134 (35%), Gaps = 19/134 (14%)

Query: 62   VENDTSP----HRERATLLEE---QLPLGKASFHIPQVQVRDEGQYQCII-----IYGVA 109
            VE + +P    HR+   L E+   Q P       +  +   D G Y C          VA
Sbjct: 3605 VEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVA 3664

Query: 110  WDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATGYPLAEVSWPNVSVPANTSHSR- 168
            +  +  T+    S        + V       L CQA G P   VSW    VP +    R 
Sbjct: 3665 FRVEIHTVPTIRS----GPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRF 3720

Query: 169  --TPEGLYQVTSVL 180
               PEG  ++  VL
Sbjct: 3721 EILPEGSLRIQPVL 3734



 Score = 29.3 bits (64), Expect = 3.9
 Identities = 32/110 (29%), Positives = 40/110 (36%), Gaps = 6/110 (5%)

Query: 89   IPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINTHILKVPE--TDEVELTCQAT 146
            I Q Q+ D G Y+C+             L+V    R      L  P      V LTC AT
Sbjct: 1943 IEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNAT 2002

Query: 147  GYPLAEVSW---PNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCV 193
            G P   + W    N   PA T   +   G   +T         GR +SCV
Sbjct: 2003 GAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGR-YSCV 2051



 Score = 29.3 bits (64), Expect = 3.9
 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 3/73 (4%)

Query: 86   SFHIPQVQVRDEGQYQCIIIY--GVAWDYKYLTLKVKASYRKIN-THILKVPETDEVELT 142
            +  I +VQ+ D G + C+     GVA     L ++V      +   + + V     VEL 
Sbjct: 3368 TLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELP 3427

Query: 143  CQATGYPLAEVSW 155
            C+A G PL  VSW
Sbjct: 3428 CEARGVPLPLVSW 3440



 Score = 28.9 bits (63), Expect = 5.0
 Identities = 17/75 (22%), Positives = 31/75 (41%), Gaps = 3/75 (4%)

Query: 84   KASFHIPQVQVRDEGQYQCIIIYGV---AWDYKYLTLKVKASYRKINTHILKVPETDEVE 140
            + S H   ++  D G+Y+C         AW+ +   L+         + +L+    +   
Sbjct: 1166 QGSVHFAAIRTSDAGRYRCEASNSAGVDAWEVELRVLEPPHWGADETSGLLERVAGENAS 1225

Query: 141  LTCQATGYPLAEVSW 155
            L C A G P  +V+W
Sbjct: 1226 LPCPARGTPKPQVTW 1240



 Score = 28.9 bits (63), Expect = 5.0
 Identities = 23/120 (19%), Positives = 41/120 (34%), Gaps = 16/120 (13%)

Query: 64   NDTSPHRERATLLEEQLPLGKASFH----------IPQVQVRDEGQYQCIIIYGVAWDYK 113
            N T   + + T  ++  PL +   H          + Q  +   G Y CI    V    K
Sbjct: 2468 NVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTK 2527

Query: 114  YLTLKVKASYRKIN------THILKVPETDEVELTCQATGYPLAEVSWPNVSVPANTSHS 167
            +  L V  +   +          + V   + + L C+A  +P   ++W     P   S +
Sbjct: 2528 HFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRN 2587



 Score = 28.5 bits (62), Expect = 6.6
 Identities = 22/91 (24%), Positives = 36/91 (39%), Gaps = 6/91 (6%)

Query: 95   RDEGQYQCIII--YGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATGYPLAE 152
            +D  Q++C++    G A     +T+ V  +     T    V     V LTC +TG P   
Sbjct: 3829 QDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFT-VTMMAPVVLTCHSTGIPAPT 3887

Query: 153  VSWPNVSV---PANTSHSRTPEGLYQVTSVL 180
            VSW           + +  +P G  ++   L
Sbjct: 3888 VSWSKAGAQLGARGSGYRVSPSGALEIGQAL 3918



 Score = 28.1 bits (61), Expect = 8.6
 Identities = 19/80 (23%), Positives = 31/80 (38%), Gaps = 9/80 (11%)

Query: 82   LGKASFHIPQVQVRDEGQYQCIIIYGVAWDYK------YLTLKVKASYRKINTHILKVPE 135
            L + S  +  V   D G Y+C     V    +      Y+   ++   RK N   +    
Sbjct: 1258 LEEGSLFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMA--- 1314

Query: 136  TDEVELTCQATGYPLAEVSW 155
               + L C A G+P+ E+ W
Sbjct: 1315 GQSLTLECDANGFPVPEIVW 1334


>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3783

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 30/117 (25%), Positives = 48/117 (41%), Gaps = 2/117 (1%)

Query: 83   GKASFHIPQVQVRDEGQYQCII--IYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVE 140
            G     I + QV D+G Y C +  + G A     LT++V  ++    T  +       + 
Sbjct: 1802 GGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLV 1861

Query: 141  LTCQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNT 197
            LTC  +G P   V+W    +P  +S             + RL+P     ++CV  NT
Sbjct: 1862 LTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENT 1918



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 31/96 (32%), Positives = 42/96 (43%), Gaps = 5/96 (5%)

Query: 72   RATLLEEQLPLGKASFHIPQVQVRDEGQYQCIII--YGVAWDYKYLTLKVKASYRKINTH 129
            R + L  QL  G  S  I + +  D G+YQC+     GVA     L L+  A   ++   
Sbjct: 2978 RGSHLRHQLQNG--SLTIRRTERDDAGRYQCLAENEMGVAKKVVILVLQ-SAPVFQVEPQ 3034

Query: 130  ILKVPETDEVELTCQATGYPLAEVSWPNVSVPANTS 165
             + V   D+V L CQATG P   + W     P   S
Sbjct: 3035 DMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRAS 3070



 Score = 37.4 bits (85), Expect = 0.014
 Identities = 28/105 (26%), Positives = 42/105 (40%), Gaps = 6/105 (5%)

Query: 80  LPLGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKAS--YRKINTHILKVPETD 137
           L   KA   + +  V D G Y C  +       K+  L V  +  +    +H L V E  
Sbjct: 837 LSADKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGH 896

Query: 138 EVELTCQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRL 182
              L+C+  G P  ++SW     P     +    GL  V++V RL
Sbjct: 897 PTRLSCECRGVPFPKISWRKDGQPLPGEGA----GLQHVSAVGRL 937



 Score = 34.7 bits (78), Expect = 0.092
 Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 3/65 (4%)

Query: 94  VRDEGQYQCIIIYGVAWDYKYLTLKVKAS---YRKINTHILKVPETDEVELTCQATGYPL 150
           V DEG+YQC+         +   L+V A    +    T  + V E   V+L C+A G P 
Sbjct: 190 VGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPT 249

Query: 151 AEVSW 155
             ++W
Sbjct: 250 PNITW 254



 Score = 34.7 bits (78), Expect = 0.092
 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 8/104 (7%)

Query: 98   GQYQCII--IYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATGYPLAEVSW 155
            G+Y C      GVA  + +LT++     + + + +  V E +EV L C+A+G P   ++W
Sbjct: 2641 GRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAE-EEVLLPCEASGIPRPTITW 2699

Query: 156  --PNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNT 197
                ++V    S    P G  ++       P    N+ C+  N+
Sbjct: 2700 QKEGLNVATGVSTQVLPGGQLRIA---HASPEDAGNYLCIAKNS 2740



 Score = 33.5 bits (75), Expect = 0.20
 Identities = 40/148 (27%), Positives = 57/148 (38%), Gaps = 12/148 (8%)

Query: 88   HIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVK-----ASYRKINTHILKVPETDEVELT 142
            ++ Q Q+  EG Y C     V    + L L+V      A  R+  T +  V +     L 
Sbjct: 939  YLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQV-SVVQDGVATLE 997

Query: 143  CQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNTHVR-- 200
            C ATG P   V+W     P         +   Q   V R +      +SCV  N   R  
Sbjct: 998  CNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAE 1057

Query: 201  ---ELT-LASIDLQSQMEPRTHPTWLLH 224
               EL+ L   +L   ++P T+ T  LH
Sbjct: 1058 RKFELSVLVPPELIGDLDPLTNITAALH 1085



 Score = 33.1 bits (74), Expect = 0.27
 Identities = 25/111 (22%), Positives = 47/111 (42%), Gaps = 7/111 (6%)

Query: 91   QVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINT---HILKVPETDEVELTCQATG 147
            Q Q +D G Y C+         +  +++V       N     ++KV +     L C  TG
Sbjct: 1130 QTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTG 1189

Query: 148  YPLAEVSWPNVSVP--ANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWN 196
            +P  +++W     P     +H  +P+G+  +  VL+       ++SC+  N
Sbjct: 1190 HPQPKLTWFKDGRPLARGDAHHISPDGV--LLQVLQANLSSAGHYSCIAAN 1238



 Score = 31.6 bits (70), Expect = 0.78
 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 7/71 (9%)

Query: 89  IPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYR----KINTHILKVPETDEVELTCQ 144
           I +V +RDEG Y C          + + LKV          +N  +L   E   V L C 
Sbjct: 570 IEKVDLRDEGIYTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVL---ENASVTLECL 626

Query: 145 ATGYPLAEVSW 155
           A+G P  +VSW
Sbjct: 627 ASGVPPPDVSW 637



 Score = 30.8 bits (68), Expect = 1.3
 Identities = 23/95 (24%), Positives = 43/95 (45%), Gaps = 13/95 (13%)

Query: 74   TLLEEQLPLGKASFH----------IPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASY 123
            T L++++P+  ++ H          + ++Q    G Y C+     A   K   + V  + 
Sbjct: 1875 TWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAVLVAP 1934

Query: 124  RKINTHILK---VPETDEVELTCQATGYPLAEVSW 155
            R  ++ + +   V E  EV L C+A G P  +V+W
Sbjct: 1935 RIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAW 1969



 Score = 30.0 bits (66), Expect = 2.3
 Identities = 37/123 (30%), Positives = 50/123 (40%), Gaps = 19/123 (15%)

Query: 79  QLPLGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINT----HILKVP 134
           QL LG+A       Q  D G Y C     V    K   L V             +++K  
Sbjct: 275 QLQLGRA-------QSSDAGVYTCKASNAVGAAEKATRLDVYVPPTIEGAGGRPYVVKAV 327

Query: 135 ETDEVELTCQATGYPLAEVSWPNVSVP-ANTSHSRTPEGLYQVTSVLRLKPPPGRN---F 190
               V L C A G+P   +SW +  +P A ++ SR    L    SVLRL+ P   +   +
Sbjct: 328 AGRPVALECVARGHPSPTLSWHHEGLPVAESNESR----LETDGSVLRLESPGEASSGLY 383

Query: 191 SCV 193
           SCV
Sbjct: 384 SCV 386



 Score = 30.0 bits (66), Expect = 2.3
 Identities = 16/68 (23%), Positives = 30/68 (44%), Gaps = 1/68 (1%)

Query: 89  IPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINTHI-LKVPETDEVELTCQATG 147
           +   +  D G+Y C+ +  V  D + + L+V      +   + + V   + V L CQ+  
Sbjct: 755 LASARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSILGEELNVSVVANESVALECQSHA 814

Query: 148 YPLAEVSW 155
            P   +SW
Sbjct: 815 MPPPVLSW 822



 Score = 30.0 bits (66), Expect = 2.3
 Identities = 29/119 (24%), Positives = 44/119 (36%), Gaps = 5/119 (4%)

Query: 83   GKASFHIPQVQVRDEGQYQCIIIYGVAWDYKY-----LTLKVKASYRKINTHILKVPETD 137
            G     IP V+  + G+Y C     V  D+ +     LT  V     +     + V  + 
Sbjct: 1520 GGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASS 1579

Query: 138  EVELTCQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWN 196
             V L C A G P+  +SW    +P + S         QV  V   +     ++ CV  N
Sbjct: 1580 TVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVAEN 1638



 Score = 29.6 bits (65), Expect = 3.0
 Identities = 35/134 (26%), Positives = 48/134 (35%), Gaps = 19/134 (14%)

Query: 62   VENDTSP----HRERATLLEE---QLPLGKASFHIPQVQVRDEGQYQCII-----IYGVA 109
            VE + +P    HR+   L E+   Q P       +  +   D G Y C          VA
Sbjct: 2323 VEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVA 2382

Query: 110  WDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATGYPLAEVSWPNVSVPANTSHSR- 168
            +  +  T+    S        + V       L CQA G P   VSW    VP +    R 
Sbjct: 2383 FRVEIHTVPTIRS----GPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRF 2438

Query: 169  --TPEGLYQVTSVL 180
               PEG  ++  VL
Sbjct: 2439 EILPEGSLRIQPVL 2452



 Score = 29.3 bits (64), Expect = 3.9
 Identities = 32/110 (29%), Positives = 40/110 (36%), Gaps = 6/110 (5%)

Query: 89  IPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINTHILKVPE--TDEVELTCQAT 146
           I Q Q+ D G Y+C+             L+V    R      L  P      V LTC AT
Sbjct: 661 IEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLTCNAT 720

Query: 147 GYPLAEVSW---PNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCV 193
           G P   + W    N   PA T   +   G   +T         GR +SCV
Sbjct: 721 GAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGR-YSCV 769



 Score = 29.3 bits (64), Expect = 3.9
 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 3/73 (4%)

Query: 86   SFHIPQVQVRDEGQYQCIIIY--GVAWDYKYLTLKVKASYRKIN-THILKVPETDEVELT 142
            +  I +VQ+ D G + C+     GVA     L ++V      +   + + V     VEL 
Sbjct: 2086 TLRISKVQLADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELP 2145

Query: 143  CQATGYPLAEVSW 155
            C+A G PL  VSW
Sbjct: 2146 CEARGVPLPLVSW 2158



 Score = 28.9 bits (63), Expect = 5.0
 Identities = 23/120 (19%), Positives = 41/120 (34%), Gaps = 16/120 (13%)

Query: 64   NDTSPHRERATLLEEQLPLGKASFH----------IPQVQVRDEGQYQCIIIYGVAWDYK 113
            N T   + + T  ++  PL +   H          + Q  +   G Y CI    V    K
Sbjct: 1186 NVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTK 1245

Query: 114  YLTLKVKASYRKIN------THILKVPETDEVELTCQATGYPLAEVSWPNVSVPANTSHS 167
            +  L V  +   +          + V   + + L C+A  +P   ++W     P   S +
Sbjct: 1246 HFQLSVLLAPTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRN 1305



 Score = 28.5 bits (62), Expect = 6.6
 Identities = 22/91 (24%), Positives = 36/91 (39%), Gaps = 6/91 (6%)

Query: 95   RDEGQYQCIII--YGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATGYPLAE 152
            +D  Q++C++    G A     +T+ V  +     T    V     V LTC +TG P   
Sbjct: 2547 QDSAQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFT-VTMMAPVVLTCHSTGIPAPT 2605

Query: 153  VSWPNVSV---PANTSHSRTPEGLYQVTSVL 180
            VSW           + +  +P G  ++   L
Sbjct: 2606 VSWSKAGAQLGARGSGYRVSPSGALEIGQAL 2636


>gi|118572606 hemicentin 1 [Homo sapiens]
          Length = 5635

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 4/83 (4%)

Query: 89   IPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINTHI----LKVPETDEVELTCQ 144
            +  + V D G+Y C+ +       K   L V A    I  H     + V E + V LTC+
Sbjct: 2350 LKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCE 2409

Query: 145  ATGYPLAEVSWPNVSVPANTSHS 167
            A+G PL  ++W     P + S+S
Sbjct: 2410 ASGIPLPSITWFKDGWPVSLSNS 2432



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 23/76 (30%), Positives = 34/76 (44%), Gaps = 3/76 (3%)

Query: 83   GKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINTHIL---KVPETDEV 139
            G     + Q  + D GQY C++      + K   L V      +  + L   KV E   V
Sbjct: 2438 GGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSV 2497

Query: 140  ELTCQATGYPLAEVSW 155
             LTC+ TG P+ E++W
Sbjct: 2498 TLTCEVTGNPVPEITW 2513



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 31/112 (27%), Positives = 50/112 (44%), Gaps = 6/112 (5%)

Query: 89   IPQVQVRDEGQYQCII--IYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQAT 146
            I   Q+ D G+Y C+     G A  Y  L + V  S     +  L V   + + LTC+ +
Sbjct: 2930 ILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVS 2989

Query: 147  GYPLAEVSWPNVSVP--ANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWN 196
            G+P  ++SW     P   NT+    P G  +   ++R K   G  ++C+  N
Sbjct: 2990 GFPPPDLSWLKNEQPIKLNTNTLIVPGG--RTLQIIRAKVSDGGEYTCIAIN 3039



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 40/134 (29%), Positives = 59/134 (44%), Gaps = 13/134 (9%)

Query: 26   PKELYIIEHGSN-VTLECNFDTGSHVNLGAITASLQKVENDTSPHRERATLLEEQLPLGK 84
            P+   I+E  SN VTL C+  TG      A   + +++EN  S        LE ++  G 
Sbjct: 3156 PEREVIVETISNPVTLTCDA-TGIPPPTIAWLKNHKRIENSDS--------LEVRILSGG 3206

Query: 85   ASFHIPQVQVRDEGQYQCII--IYGVAWDYKYLTLKVKASYRKINTHI-LKVPETDEVEL 141
            +   I + Q  D G Y CI   + G A  Y +L+++V  S         + V   + VEL
Sbjct: 3207 SKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVEL 3266

Query: 142  TCQATGYPLAEVSW 155
             C A G P   + W
Sbjct: 3267 VCNANGIPTPLIQW 3280



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 35/142 (24%), Positives = 57/142 (40%), Gaps = 9/142 (6%)

Query: 82   LGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKV-KASYRKINTHILKVPETDEVE 140
            L   +  I   Q+   G+Y C+        ++++TL V +    +     L V   + + 
Sbjct: 3947 LSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELHVILNNPIL 4006

Query: 141  LTCQATGYPLAEVSWPNVSVPANTS---HSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNT 197
            L C+ATG P   ++W    +  NTS   H+  P G  Q++  +R        + CV  N 
Sbjct: 4007 LPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVR---EDAGTYMCVAQNP 4063

Query: 198  HVRELTLASIDLQSQMEPRTHP 219
                  L  I L  Q+ P   P
Sbjct: 4064 --AGTALGKIKLNVQVPPVISP 4083



 Score = 38.5 bits (88), Expect = 0.006
 Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 2/70 (2%)

Query: 88   HIPQVQVRDEGQYQCIIIYGVAWDYK--YLTLKVKASYRKINTHILKVPETDEVELTCQA 145
            HI + +V D GQY C  I     D K  +L + V  S       ++    ++ V LTC A
Sbjct: 3116 HIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTCDA 3175

Query: 146  TGYPLAEVSW 155
            TG P   ++W
Sbjct: 3176 TGIPPPTIAW 3185



 Score = 37.7 bits (86), Expect = 0.011
 Identities = 49/187 (26%), Positives = 72/187 (38%), Gaps = 24/187 (12%)

Query: 26   PKELYIIEHGSNVTLECNFDTGSHVNLGAITASLQKVENDTSPHRERATLLEEQLPLGKA 85
            P E+ ++  G  VTL C   +     L     +  K     SP   R T L    P G  
Sbjct: 1086 PVEISVLA-GEEVTLPCEVKS-----LPPPIITWAKETQLISPFSPRHTFL----PSG-- 1133

Query: 86   SFHIPQVQVRDEGQYQCII--IYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTC 143
            S  I + +  D G Y C+   I G       L + V    ++   H LKV     V++ C
Sbjct: 1134 SMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQRGPKH-LKVQVGQRVDIPC 1192

Query: 144  QATGYPLAEVSWP---NVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWN---T 197
             A G PL  ++W    +  +     H   P+G     S+ +  P     ++CV  N   T
Sbjct: 1193 NAQGTPLPVITWSKGGSTMLVDGEHHVSNPDG---TLSIDQATPSDAGIYTCVATNIAGT 1249

Query: 198  HVRELTL 204
               E+TL
Sbjct: 1250 DETEITL 1256



 Score = 35.8 bits (81), Expect = 0.041
 Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 1/88 (1%)

Query: 86   SFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKA-SYRKINTHILKVPETDEVELTCQ 144
            S HI +VQ++D G+Y C+       + K  ++ V      +    IL   E   V L C+
Sbjct: 944  SLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIPVTLPCK 1003

Query: 145  ATGYPLAEVSWPNVSVPANTSHSRTPEG 172
            A+G P   V W       +TS ++   G
Sbjct: 1004 ASGNPKPSVIWSKKGELISTSSAKFSAG 1031



 Score = 35.0 bits (79), Expect = 0.070
 Identities = 28/100 (28%), Positives = 41/100 (41%), Gaps = 5/100 (5%)

Query: 65   DTSPHRERATLLEE--QLPLGKASFHIPQVQVRDEGQYQCII--IYGVAWDYKYLTLKVK 120
            D + H++   ++E   Q  L   S  I  VQ  D G Y C+   + G +     LT+ V 
Sbjct: 4109 DITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVP 4168

Query: 121  ASYRKINTHILKVPETDEVELTCQATGYPLAEVSWPNVSV 160
               R    H   V E  +  L C A G P   ++W   +V
Sbjct: 4169 PRIRSTEGHYT-VNENSQAILPCVADGIPTPAINWKKDNV 4207



 Score = 33.1 bits (74), Expect = 0.27
 Identities = 23/99 (23%), Positives = 40/99 (40%), Gaps = 3/99 (3%)

Query: 88   HIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKA--SYRKINTHILKVPETDEVELTCQA 145
            HI    V D G+Y C+       D + + L+V    S     T++  +    +  L C+A
Sbjct: 3769 HIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNV-QTTLACEA 3827

Query: 146  TGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRLKP 184
            TG P   ++W       N   ++    L    S++ + P
Sbjct: 3828 TGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISP 3866



 Score = 32.3 bits (72), Expect = 0.46
 Identities = 19/77 (24%), Positives = 35/77 (45%), Gaps = 1/77 (1%)

Query: 89   IPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVK-ASYRKINTHILKVPETDEVELTCQATG 147
            I   Q+ D G Y+C+ I        + +L+V  A     + +++ V   + V L C+A G
Sbjct: 1978 IESAQISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARG 2037

Query: 148  YPLAEVSWPNVSVPANT 164
             P   ++W     P ++
Sbjct: 2038 IPAPSLTWLKDGSPVSS 2054



 Score = 32.0 bits (71), Expect = 0.59
 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 4/80 (5%)

Query: 89   IPQVQVRDEGQYQCIIIYGVAWDYKY---LTLKVKASYRKINTHILKVPETDEVELTCQA 145
            I Q QV + G Y+C+     A D+K    +T+ V  + +        V +   V L C A
Sbjct: 1792 IAQAQVSNTGLYRCMAA-NTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIA 1850

Query: 146  TGYPLAEVSWPNVSVPANTS 165
             G P   ++W     P NT+
Sbjct: 1851 NGIPNPSITWLKDDQPVNTA 1870



 Score = 31.6 bits (70), Expect = 0.78
 Identities = 19/76 (25%), Positives = 34/76 (44%), Gaps = 3/76 (3%)

Query: 82  LGKASFHIPQVQVRDEGQYQCIIIY--GVAWDYKYLTLKVKASYRKINTHILKVPETDEV 139
           L   S  +  V+  D G+Y C++    G +    +LT++       +  +        EV
Sbjct: 571 LANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKN-QSFTGGSEV 629

Query: 140 ELTCQATGYPLAEVSW 155
            + C ATGYP  +++W
Sbjct: 630 SIMCSATGYPKPKIAW 645



 Score = 31.6 bits (70), Expect = 0.78
 Identities = 20/81 (24%), Positives = 36/81 (44%), Gaps = 3/81 (3%)

Query: 88   HIPQVQVRDEGQYQCIIIYGVAWDYK--YLTLKVKASYRKIN-THILKVPETDEVELTCQ 144
            H+   +  D+G+YQC +        K   LT+ +  S +  N T  + V     ++L C+
Sbjct: 1511 HLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECE 1570

Query: 145  ATGYPLAEVSWPNVSVPANTS 165
              G P+  ++W     P  +S
Sbjct: 1571 TRGLPMPAITWYKDGQPIMSS 1591



 Score = 31.6 bits (70), Expect = 0.78
 Identities = 20/79 (25%), Positives = 41/79 (51%), Gaps = 5/79 (6%)

Query: 89   IPQVQVRDEGQYQCIIIYGVAWDYKY--LTLKVKASYRKINTHILKVPETDEVELTCQAT 146
            +  V + D G Y C+       D     LT+ V  ++ ++   +  + + +++ L+C+AT
Sbjct: 4226 LENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDV-SLNKGEQLRLSCKAT 4284

Query: 147  GYPLAEVSWP--NVSVPAN 163
            G PL +++W   N  +PA+
Sbjct: 4285 GIPLPKLTWTFNNNIIPAH 4303



 Score = 30.8 bits (68), Expect = 1.3
 Identities = 22/76 (28%), Positives = 30/76 (39%), Gaps = 3/76 (3%)

Query: 82   LGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKY--LTLKVKASYRKINTHILKVPETDEV 139
            L   S  I    V D   Y+C +  G   D +   LT++V  S     T  L       V
Sbjct: 3856 LSSGSLVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAV 3915

Query: 140  ELTCQATGYPLAEVSW 155
             +TC A+G P   + W
Sbjct: 3916 -ITCTASGVPFPSIHW 3930



 Score = 30.0 bits (66), Expect = 2.3
 Identities = 18/63 (28%), Positives = 25/63 (39%), Gaps = 3/63 (4%)

Query: 96   DEGQYQCIIIYGVAWDYKYLTLKVKASYRKINTHI---LKVPETDEVELTCQATGYPLAE 152
            D G+Y C  I       KY  + V      I T+    + V    +V L CQ  G P  +
Sbjct: 1425 DAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPD 1484

Query: 153  VSW 155
            + W
Sbjct: 1485 IHW 1487



 Score = 30.0 bits (66), Expect = 2.3
 Identities = 19/78 (24%), Positives = 32/78 (41%), Gaps = 5/78 (6%)

Query: 83   GKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKA-----SYRKINTHILKVPETD 137
            G  +  I + +V D G+Y CI I       K  +L V        +   +  ++ V E  
Sbjct: 3016 GGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGT 3075

Query: 138  EVELTCQATGYPLAEVSW 155
             V L C++   P   ++W
Sbjct: 3076 SVSLECESNAVPPPVITW 3093



 Score = 30.0 bits (66), Expect = 2.3
 Identities = 24/111 (21%), Positives = 39/111 (35%), Gaps = 3/111 (2%)

Query: 89   IPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKIN---THILKVPETDEVELTCQA 145
            I + QV D   Y C+       D K+  L+V A     N   T  + V +     + C  
Sbjct: 3400 IVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACIT 3459

Query: 146  TGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWN 196
             G P   ++W     P       T      V  +L+ +      ++C+  N
Sbjct: 3460 DGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASN 3510



 Score = 29.6 bits (65), Expect = 3.0
 Identities = 21/73 (28%), Positives = 31/73 (42%), Gaps = 13/73 (17%)

Query: 91   QVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINTHILKVPETDEV--------ELT 142
            + +  D G+Y CI         K+  LKV         HI    E +E+        ELT
Sbjct: 3495 KAETEDSGKYTCIASNEAGEVSKHFILKVLEP-----PHINGSEEHEEISVIVNNPLELT 3549

Query: 143  CQATGYPLAEVSW 155
            C A+G P  +++W
Sbjct: 3550 CIASGIPAPKMTW 3562



 Score = 29.3 bits (64), Expect = 3.9
 Identities = 34/149 (22%), Positives = 57/149 (38%), Gaps = 9/149 (6%)

Query: 22   TVTVPKELYIIEHGSNVTLECNFDTGSHVNLGAITASLQKVENDTSPHRERATLLEEQLP 81
            T+ +P  +     G NVT + +    S + L   T  L           +      + L 
Sbjct: 1541 TIYIPPSI----KGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALY 1596

Query: 82   LGKASF-HIPQVQVRDEGQYQCII--IYGVAWDYKYLTLKVKASYR-KINTHILK-VPET 136
            + K  + HIP+ QV D   Y C +  + G A    ++ + V       + T + K V   
Sbjct: 1597 IDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIA 1656

Query: 137  DEVELTCQATGYPLAEVSWPNVSVPANTS 165
              + L C+A G P   ++W    VP   +
Sbjct: 1657 HSLTLECKAAGNPSPILTWLKDGVPVKAN 1685



 Score = 29.3 bits (64), Expect = 3.9
 Identities = 32/139 (23%), Positives = 51/139 (36%), Gaps = 13/139 (9%)

Query: 69   HRERATLLEEQ---LPLGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRK 125
            H++   L E++   +  G     I  VQV   G+Y C+         +  +L V  S   
Sbjct: 2514 HKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTI 2573

Query: 126  I------NTHILKVPETDEVELTCQATGYPLAEVSWPNVSVP--ANTSHSRTPEGLYQVT 177
                   N   + V       L C+A  YP A ++W     P  +N +    P G  +  
Sbjct: 2574 AGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGG--RTL 2631

Query: 178  SVLRLKPPPGRNFSCVFWN 196
             +L  +      +SCV  N
Sbjct: 2632 QILNAQEDNAGRYSCVATN 2650



 Score = 28.5 bits (62), Expect = 6.6
 Identities = 36/179 (20%), Positives = 68/179 (37%), Gaps = 20/179 (11%)

Query: 25   VPKELYIIEHGSNVTLECNFDTGSHVNLGAITASLQKVEND---TSPHRERATLLEEQLP 81
            +P ++ ++  G NV L CN +       G  T  +Q +++     S   ER      ++ 
Sbjct: 3252 IPSDVSVLL-GENVELVCNAN-------GIPTPLIQWLKDGKPIASGETERI-----RVS 3298

Query: 82   LGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASY----RKINTHILKVPETD 137
               ++ +I      D G+Y C+       + +   L V  +      K     L      
Sbjct: 3299 ANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDT 3358

Query: 138  EVELTCQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWN 196
             + + C+ATG P  +++W    +P   S         QV  ++R +      ++CV  N
Sbjct: 3359 SINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASN 3417


>gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]
          Length = 437

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 34/131 (25%), Positives = 58/131 (44%), Gaps = 12/131 (9%)

Query: 32  IEHGSNVTLECNFDTGSHVNLGAITASLQKVENDTSPHRERATLLEEQLPLGKASFH--- 88
           +  G    L C  D   + +L     + Q +  D     ++  L + ++ L +AS+H   
Sbjct: 36  VVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFD-----DKKALRDNRIELVRASWHELS 90

Query: 89  --IPQVQVRDEGQYQC-IIIYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQA 145
             +  V + DEGQY C +    V     YLT+       +I+     V E D ++LTC+ 
Sbjct: 91  ISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQLTCKT 150

Query: 146 TG-YPLAEVSW 155
           +G  P A++ W
Sbjct: 151 SGSKPAADIRW 161


>gi|222418658 butyrophilin, subfamily 3, member A1 isoform c [Homo
           sapiens]
          Length = 461

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 39/137 (28%), Positives = 65/137 (47%), Gaps = 18/137 (13%)

Query: 1   MIFLLLMLSLELQLHQI----AALFTVTVPKELYIIEHGSNVTLECN-FDTGSH--VNLG 53
           + FLLL   + L L Q+    +A F+V  P    +   G +  L C+ F T S   + L 
Sbjct: 7   LAFLLLNFRVCLLLLQLLMPHSAQFSVLGPSGPILAMVGEDADLPCHLFPTMSAETMELK 66

Query: 54  AITASLQKVEN-----------DTSPHRERATLLEEQLPLGKASFHIPQVQVRDEGQYQC 102
            +++SL++V N            ++P+R R ++L + +  GKA+  I  V   D G+Y C
Sbjct: 67  WVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLC 126

Query: 103 IIIYGVAWDYKYLTLKV 119
               G  ++   + LKV
Sbjct: 127 YFQDGDFYEKALVELKV 143


>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
          Length = 4391

 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 30/129 (23%), Positives = 54/129 (41%), Gaps = 8/129 (6%)

Query: 89   IPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATGY 148
            I  V++ D GQY+C           ++ L V+A  +      ++VP        C A+GY
Sbjct: 3542 IAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEVRVPAGSAAVFPCIASGY 3601

Query: 149  PLAEVSWPNV--SVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNTHVRELTLAS 206
            P  ++SW  +  S+P +   SR    +  + SV   +P     + C   N   +    A 
Sbjct: 3602 PTPDISWSKLDGSLPPD---SRLENNMLMLPSV---RPQDAGTYVCTATNRQGKVKAFAH 3655

Query: 207  IDLQSQMEP 215
            + +  ++ P
Sbjct: 3656 LQVPERVVP 3664



 Score = 30.8 bits (68), Expect = 1.3
 Identities = 27/83 (32%), Positives = 32/83 (38%), Gaps = 9/83 (10%)

Query: 89   IPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKAS------YRKINTHILKVPETDEVELT 142
            I  VQ+ D G Y C      A D    TL V+AS         I+   L V      E  
Sbjct: 1827 IRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFR 1886

Query: 143  CQATGYPLAEVSW---PNVSVPA 162
            C ATG P   + W   P   +PA
Sbjct: 1887 CSATGSPTPTLEWTGGPGGQLPA 1909



 Score = 28.9 bits (63), Expect = 5.0
 Identities = 28/136 (20%), Positives = 47/136 (34%), Gaps = 14/136 (10%)

Query: 34   HGSNVTLECNFDTGSHVNLGAITASLQKVENDTSPHR----ERATLLEEQLPLGKASFHI 89
            H   V      ++ S       T  L  +    +PH     +R   L  +  +  +   I
Sbjct: 2528 HSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQIVGSRLRI 2587

Query: 90   PQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYR----------KINTHILKVPETDEV 139
            PQV   D G+Y C +  G       L + ++ S            +I +    V E   +
Sbjct: 2588 PQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTL 2647

Query: 140  ELTCQATGYPLAEVSW 155
            +L C     P A ++W
Sbjct: 2648 DLNCVVARQPQAIITW 2663



 Score = 28.5 bits (62), Expect = 6.6
 Identities = 26/106 (24%), Positives = 42/106 (39%), Gaps = 6/106 (5%)

Query: 96   DEGQYQCII--IYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATGYPLAEV 153
            + G Y+C+    YGVA     L++    +   +    + V     V L C + G P +  
Sbjct: 3085 NHGTYRCVASNAYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSSA 3144

Query: 154  SWPNVSVPANTSHSRTPEGLYQVTSVLRL---KPPPGRNFSCVFWN 196
             W  +S        RT  GL    +VL++   KP     + C+  N
Sbjct: 3145 RWTRISSTPAKLEQRT-YGLMDSHAVLQISSAKPSDAGTYVCLAQN 3189



 Score = 28.1 bits (61), Expect = 8.6
 Identities = 27/101 (26%), Positives = 38/101 (37%), Gaps = 11/101 (10%)

Query: 79   QLPLGKASFH-----IPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYR---KINTHI 130
            QLP  KA  H     +P V+  D+ QY C              L V        +++   
Sbjct: 1906 QLP-AKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPER 1964

Query: 131  LKVPETDEVELTCQATGYPLAEVSW--PNVSVPANTSHSRT 169
             +V     V L C+A G P A ++W     S+P      RT
Sbjct: 1965 TQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERT 2005


>gi|99028881 V-set domain containing T cell activation inhibitor 1
           [Homo sapiens]
          Length = 282

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 50/182 (27%), Positives = 79/182 (43%), Gaps = 23/182 (12%)

Query: 70  RERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKA-SYRKINT 128
           R R  +  +Q+ +G AS  +  VQ+ D G Y+C II         L  K  A S  ++N 
Sbjct: 98  RGRTAVFADQVIVGNASLRLKNVQLTDAGTYKCYIITSKGKGNANLEYKTGAFSMPEVNV 157

Query: 129 HILKVPETDEVELTCQA-TGYPLAEVSW-------PNVSVPANTSHSRTPEGL-YQVTSV 179
                 ET    L C+A   +P   V W        N S  +NTS     E +  +V SV
Sbjct: 158 DYNASSET----LRCEAPRWFPQPTVVWASQVDQGANFSEVSNTSFELNSENVTMKVVSV 213

Query: 180 LRLKPPPGRNFSCVFWNTHVRELTLASIDL---QSQMEPRTHPTWLLHIFIPFCIIAFIF 236
           L         +SC+  N    ++  A+ D+   +S+++ R+H   LL+     C+ +F  
Sbjct: 214 L-YNVTINNTYSCMIEN----DIAKATGDIKVTESEIKRRSH-LQLLNSKASLCVSSFFA 267

Query: 237 IA 238
           I+
Sbjct: 268 IS 269


>gi|5031927 skeletal muscle receptor tyrosine kinase [Homo sapiens]
          Length = 869

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 41/137 (29%), Positives = 59/137 (43%), Gaps = 25/137 (18%)

Query: 26  PKELYIIEHGSNVTLECNFDTGSHVNLGAITASLQKVENDTSPHRERATLLEEQLPLGKA 85
           P  + IIE G    L C         +G    S+  ++ D SP RE + +      L   
Sbjct: 127 PINVKIIE-GLKAVLPCT-------TMGNPKPSVSWIKGD-SPLRENSRIAV----LESG 173

Query: 86  SFHIPQVQVRDEGQYQCIIIYGVAWDY-KYLTLKVKASYRKINTHILKVPETDE------ 138
           S  I  VQ  D GQY+C+    +   Y K + L+V+   R     IL+ PE+        
Sbjct: 174 SLRIHNVQKEDAGQYRCVAKNSLGTAYSKVVKLEVEVFAR-----ILRAPESHNVTFGSF 228

Query: 139 VELTCQATGYPLAEVSW 155
           V L C ATG P+  ++W
Sbjct: 229 VTLHCTATGIPVPTITW 245


>gi|4885123 CD80 antigen precursor [Homo sapiens]
          Length = 288

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 31/115 (26%), Positives = 53/115 (46%), Gaps = 10/115 (8%)

Query: 96  DEGQYQCIIIYGVAWDYK-----YLTLKVKASYRKINTHILKVPETDEVELTCQAT-GYP 149
           DEG Y+C+++      +K      +TL VKA +   +    ++P ++   + C  + G+P
Sbjct: 110 DEGTYECVVLKYEKDAFKREHLAEVTLSVKADFPTPSISDFEIPTSNIRRIICSTSGGFP 169

Query: 150 LAEVSWPNVSV---PANTSHSRTPE-GLYQVTSVLRLKPPPGRNFSCVFWNTHVR 200
              +SW          NT+ S+ PE  LY V+S L        +F C+    H+R
Sbjct: 170 EPHLSWLENGEELNAINTTVSQDPETELYAVSSKLDFNMTTNHSFMCLIKYGHLR 224


>gi|90903245 CD200 antigen isoform b [Homo sapiens]
          Length = 294

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 32/116 (27%), Positives = 45/116 (38%), Gaps = 18/116 (15%)

Query: 79  QLPLGKASFHIPQVQVRDEGQYQCII-------IYGVAWDYKYLTLKVKASYRKINTHIL 131
           QL L  ++     + + DEG Y C+        I G A    Y+   V   Y+    H+ 
Sbjct: 123 QLGLQNSTITFWNITLEDEGCYMCLFNTFGFGKISGTACLTVYVQPIVSLHYKFSEDHL- 181

Query: 132 KVPETDEVELTCQATGYPLAEVSW--PNVSVPANTSHSRTPEGLYQVTSVLRLKPP 185
                    +TC AT  P   V W  P   +  +T     P G   VTS+L +K P
Sbjct: 182 --------NITCSATARPAPMVFWKVPRSGIENSTVTLSHPNGTTSVTSILHIKDP 229


>gi|90903247 CD200 antigen isoform a precursor [Homo sapiens]
          Length = 269

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 32/116 (27%), Positives = 45/116 (38%), Gaps = 18/116 (15%)

Query: 79  QLPLGKASFHIPQVQVRDEGQYQCII-------IYGVAWDYKYLTLKVKASYRKINTHIL 131
           QL L  ++     + + DEG Y C+        I G A    Y+   V   Y+    H+ 
Sbjct: 98  QLGLQNSTITFWNITLEDEGCYMCLFNTFGFGKISGTACLTVYVQPIVSLHYKFSEDHL- 156

Query: 132 KVPETDEVELTCQATGYPLAEVSW--PNVSVPANTSHSRTPEGLYQVTSVLRLKPP 185
                    +TC AT  P   V W  P   +  +T     P G   VTS+L +K P
Sbjct: 157 --------NITCSATARPAPMVFWKVPRSGIENSTVTLSHPNGTTSVTSILHIKDP 204


>gi|157739930 TAP binding protein-like [Homo sapiens]
          Length = 468

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 56/227 (24%), Positives = 95/227 (41%), Gaps = 31/227 (13%)

Query: 35  GSNVTLECNFDTGSHVNLGAITASLQK----------VENDTSPHRERATLLEEQLPLGK 84
           GS+ +L+C F     ++L ++   LQ                   R+ ATL   QL + +
Sbjct: 205 GSSASLDCGFSMAPGLDLISVEWRLQHKGRGQLVYSWTAGQGQAVRKGATLEPAQLGMAR 264

Query: 85  -ASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTC 143
            AS  +P + ++DEG Y C I   +    + + L ++AS +     +    E     L C
Sbjct: 265 DASLTLPGLTIQDEGTYICQITTSLYRAQQIIQLNIQASPK---VRLSLANEALLPTLIC 321

Query: 144 QATG-YPL-AEVSW---------PNVSVPANTSHSRTPEGLYQVTSVLRLKP-PPGRNFS 191
              G YPL   V+W           VS  + +S  ++  G Y ++S L  +P   G  ++
Sbjct: 322 DIAGYYPLDVVVTWTREELGGSPAQVSGASFSSLRQSVAGTYSISSSLTAEPGSAGATYT 381

Query: 192 CVFWNTHVRELTLASIDLQSQMEPRTHPTWLLHIFI-PFCIIAFIFI 237
           C   +  + E   AS    +Q+ P    T L  IF     ++A +F+
Sbjct: 382 CQVTHISLEEPLGAS----TQVVPPERRTALGVIFASSLFLLALMFL 424


>gi|139948432 adlican [Homo sapiens]
          Length = 2828

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 30/120 (25%), Positives = 58/120 (48%), Gaps = 12/120 (10%)

Query: 86   SFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKV---KASYRKINTHILKVPETDEVELT 142
            + +  +V +R+EG Y C     V  D   + +KV    A+ R      ++VP  D V + 
Sbjct: 2308 TLYFNEVGMREEGDYTCFAENQVGKDEMRVRVKVVTAPATIRNKTYLAVQVPYGDVVTVA 2367

Query: 143  CQATGYPLAEVSW---PNVSVPANTSHSRTPEGLYQVTSVL--RLKPPPGRNFSCVFWNT 197
            C+A G P+ +V+W    N  +P ++   +    +YQ  ++L  + +     N++C+  N+
Sbjct: 2368 CEAKGEPMPKVTWLSPTNKVIPTSSEKYQ----IYQDGTLLIQKAQRSDSGNYTCLVRNS 2423



 Score = 36.2 bits (82), Expect = 0.032
 Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 7/72 (9%)

Query: 89   IPQVQVRDEGQYQCIIIYGVAWDYKYLTLKV-----KASYRKINTHILKVPETDEVELTC 143
            +  V  +D G Y C+    V  DY  L + V     K  +++ N H  KV    ++++ C
Sbjct: 2208 VKSVTDKDAGDYLCVARNKVGDDYVVLKVDVVMKPAKIEHKEENDH--KVFYGGDLKVDC 2265

Query: 144  QATGYPLAEVSW 155
             ATG P  E+SW
Sbjct: 2266 VATGLPNPEISW 2277



 Score = 32.0 bits (71), Expect = 0.59
 Identities = 30/107 (28%), Positives = 41/107 (38%), Gaps = 9/107 (8%)

Query: 82  LGKASFHIPQVQVRDEGQYQCIIIYGVAWD---YKYLTLKVKASYRKINTHILKVPETDE 138
           L      I  ++  D G YQCI       D   Y+ L         + +T  +     + 
Sbjct: 535 LSSGWLRIKSMEPSDSGLYQCIAQVRDEMDRMVYRVLVQSPSTQPAEKDTVTIGKNPGES 594

Query: 139 VELTCQATGYPLAEVSW--PN---VSVPANTSH-SRTPEGLYQVTSV 179
           V L C A   P A +SW  PN   ++  ANTSH    P G   +  V
Sbjct: 595 VTLPCNALAIPEAHLSWILPNRRIINDLANTSHVYMLPNGTLSIPKV 641



 Score = 32.0 bits (71), Expect = 0.59
 Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 13/84 (15%)

Query: 22  TVTVPKELYIIEHGSNVTLECNFDTGSHVNLGAITASLQKVENDTSPHRERATLLEEQLP 81
           TVT+ K       G +VTL CN       +L  I  + +++ ND +      T     LP
Sbjct: 584 TVTIGKN-----PGESVTLPCNALAIPEAHLSWILPN-RRIINDLAN-----TSHVYMLP 632

Query: 82  LGKASFHIPQVQVRDEGQYQCIII 105
            G  S  IP+VQV D G Y+C+ +
Sbjct: 633 NGTLS--IPKVQVSDSGYYRCVAV 654



 Score = 32.0 bits (71), Expect = 0.59
 Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 3/70 (4%)

Query: 89   IPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKI---NTHILKVPETDEVELTCQA 145
            I +VQV+D GQY C        D   + L V     +I   +   + V   D + + C A
Sbjct: 1915 IRKVQVQDRGQYMCTASNLHGLDRMVVLLSVTVQQPQILASHYQDVTVYLGDTIAMECLA 1974

Query: 146  TGYPLAEVSW 155
             G P  ++SW
Sbjct: 1975 KGTPAPQISW 1984



 Score = 30.4 bits (67), Expect = 1.7
 Identities = 19/74 (25%), Positives = 29/74 (39%), Gaps = 7/74 (9%)

Query: 89   IPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVE-------L 141
            I + Q  D G Y C++      D K + + V     KIN +   +    E+        +
Sbjct: 2405 IQKAQRSDSGNYTCLVRNSAGEDRKTVWIHVNVQPPKINGNPNPITTVREIAAGGSRKLI 2464

Query: 142  TCQATGYPLAEVSW 155
             C+A G P   V W
Sbjct: 2465 DCKAEGIPTPRVLW 2478



 Score = 28.1 bits (61), Expect = 8.6
 Identities = 31/91 (34%), Positives = 39/91 (42%), Gaps = 9/91 (9%)

Query: 135  ETDEVELTCQATGYPLAEVSWPNVSVPA----NTSHSRTPEGLYQVTSVLRLKPPPGR-N 189
            ETD V   C+ATG P   V+W  VS  A    NT   R  E L   T V+R      R  
Sbjct: 1868 ETDTV-FPCEATGKPKPFVTWTKVSTGALMTPNTRIQRF-EVLKNGTLVIRKVQVQDRGQ 1925

Query: 190  FSCVFWNTH--VRELTLASIDLQSQMEPRTH 218
            + C   N H   R + L S+ +Q      +H
Sbjct: 1926 YMCTASNLHGLDRMVVLLSVTVQQPQILASH 1956


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,570,941
Number of Sequences: 37866
Number of extensions: 483552
Number of successful extensions: 2221
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 152
Number of HSP's that attempted gapping in prelim test: 1685
Number of HSP's gapped (non-prelim): 629
length of query: 273
length of database: 18,247,518
effective HSP length: 101
effective length of query: 172
effective length of database: 14,423,052
effective search space: 2480764944
effective search space used: 2480764944
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.