Guide to the Human Genome
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Name: ICOSLG Sequence: fasta or formatted (302aa) NCBI GI: 27477039
Description:

inducible T-cell co-stimulator ligand

Referenced in:

Butyrophilin Family
T cells

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.0         18           2
 C cysteine            3.0          9           2
 D aspartate           5.0         15           1
 E glutamate           5.3         16           1
 F phenylalanine       3.3         10           1
 G glycine             5.6         17           1
 H histidine           2.0          6           1
 I isoleucine          3.3         10           1
 K lysine              2.0          6           1
 L leucine            11.3         34           2
 M methionine          1.7          5           1
 N asparagine          6.0         18           1
 P proline             4.3         13           1
 Q glutamine           4.6         14           2
 R arginine            5.3         16           1
 S serine              9.6         29           2
 T threonine           6.3         19           1
 V valine             11.3         34           3
 W tryptophan          1.7          5           1
 Y tyrosine            2.6          8           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   inducible T-cell co-stimulator ligand 
CD276                 0.135   CD276 antigen isoform b 
CD276                 0.127   CD276 antigen isoform a 
BTN1A1                0.070   butyrophilin, subfamily 1, member A1 
CD86                  0.060   CD86 antigen isoform 2 precursor 
CD86                  0.060   CD86 antigen isoform 1 
CD80                  0.060   CD80 antigen precursor 
BTNL8                 0.055   butyrophilin-like 8 isoform 4 precursor 
BTNL8                 0.055   butyrophilin-like 8 isoform 2 precursor 
BTNL8                 0.055   butyrophilin-like 8 isoform 1 precursor 
CD274                 0.055   CD274 molecule 
BTNL2                 0.055   butyrophilin-like 2 
HHLA2                 0.053   HERV-H LTR-associating 2 
BTN3A2                0.051   butyrophilin, subfamily 3, member A2 precursor [Homo...
PDCD1LG2              0.048   programmed cell death 1 ligand 2 
VTCN1                 0.046   V-set domain containing T cell activation inhibitor ...
BTN3A1                0.046   butyrophilin, subfamily 3, member A1 isoform b [Homo...
BTN3A1                0.046   butyrophilin, subfamily 3, member A1 isoform d [Hom...
BTN3A1                0.046   butyrophilin, subfamily 3, member A1 isoform a [Homo...
BTN3A3                0.043   butyrophilin, subfamily 3, member A3 isoform a 
BTN3A3                0.039   butyrophilin, subfamily 3, member A3 isoform b [Homo...
BTN2A1                0.039   butyrophilin, subfamily 2, member A1 isoform 1 precur...
BTN2A1                0.039   butyrophilin, subfamily 2, member A1 isoform 2 precu...
BTN2A2                0.036   butyrophilin, subfamily 2, member A2 isoform a 
BTNL9                 0.034   butyrophilin-like 9 
MCAM                  0.033   melanoma cell adhesion molecule 
CD200                 0.029   CD200 antigen isoform b 
CD200                 0.029   CD200 antigen isoform a precursor 
SIRPA                 0.029   signal-regulatory protein alpha precursor 
SIRPA                 0.029   signal-regulatory protein alpha precursor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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