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Search of human proteins with 189083719
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|189083719 laminin, beta 3 precursor [Homo sapiens]
(1172 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62868217 laminin, beta 3 precursor [Homo sapiens] 2418 0.0
gi|62868215 laminin, beta 3 precursor [Homo sapiens] 2418 0.0
gi|189083719 laminin, beta 3 precursor [Homo sapiens] 2418 0.0
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 468 e-131
gi|143770880 laminin, beta 4 [Homo sapiens] 447 e-125
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 424 e-118
gi|21264602 laminin alpha 5 [Homo sapiens] 323 5e-88
gi|93204871 netrin 4 [Homo sapiens] 305 1e-82
gi|219842266 usherin isoform B [Homo sapiens] 298 3e-80
gi|219842259 usherin isoform A [Homo sapiens] 298 3e-80
gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 276 6e-74
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 269 1e-71
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 269 1e-71
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 253 6e-67
gi|148613884 netrin 1 [Homo sapiens] 223 6e-58
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 213 1e-54
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 200 6e-51
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 200 6e-51
gi|5453810 netrin 3 [Homo sapiens] 196 1e-49
gi|164414431 netrin G1 isoform 1 [Homo sapiens] 162 2e-39
gi|24308065 netrin 5 [Homo sapiens] 156 1e-37
gi|190014607 netrin G2 [Homo sapiens] 152 2e-36
gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens] 138 4e-32
gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens] 135 2e-31
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 120 6e-27
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 116 1e-25
gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] 114 5e-25
gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo... 112 2e-24
gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo... 112 2e-24
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 109 2e-23
>gi|62868217 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 2418 bits (6266), Expect = 0.0
Identities = 1172/1172 (100%), Positives = 1172/1172 (100%)
Query: 1 MRPFFLLCFALPGLLHAQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYCTQYG 60
MRPFFLLCFALPGLLHAQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYCTQYG
Sbjct: 1 MRPFFLLCFALPGLLHAQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYCTQYG 60
Query: 61 EWQMKCCKCDSRQPHNYYSHRVENVASSSGPMRWWQSQNDVNPVSLQLDLDRRFQLQEVM 120
EWQMKCCKCDSRQPHNYYSHRVENVASSSGPMRWWQSQNDVNPVSLQLDLDRRFQLQEVM
Sbjct: 61 EWQMKCCKCDSRQPHNYYSHRVENVASSSGPMRWWQSQNDVNPVSLQLDLDRRFQLQEVM 120
Query: 121 MEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFPRVRQGRPQSWQDVRCQSLPQRP 180
MEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFPRVRQGRPQSWQDVRCQSLPQRP
Sbjct: 121 MEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFPRVRQGRPQSWQDVRCQSLPQRP 180
Query: 181 NARLNGGKVQLNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVPQRGYHPPSAYYA 240
NARLNGGKVQLNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVPQRGYHPPSAYYA
Sbjct: 181 NARLNGGKVQLNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVPQRGYHPPSAYYA 240
Query: 241 VSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNR 300
VSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNR
Sbjct: 241 VSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNR 300
Query: 301 PWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQL 360
PWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQL
Sbjct: 301 PWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQL 360
Query: 361 HYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGL 420
HYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGL
Sbjct: 361 HYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGL 420
Query: 421 TYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEP 480
TYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEP
Sbjct: 421 TYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEP 480
Query: 481 CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRG 540
CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRG
Sbjct: 481 CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRG 540
Query: 541 TEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDADLREQALRFG 600
TEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDADLREQALRFG
Sbjct: 541 TEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDADLREQALRFG 600
Query: 601 RLRNATASLWSGPGLEDRGLASRILDAKSKIEQIRAVLSSPAVTEQEVAQVASAILSLRR 660
RLRNATASLWSGPGLEDRGLASRILDAKSKIEQIRAVLSSPAVTEQEVAQVASAILSLRR
Sbjct: 601 RLRNATASLWSGPGLEDRGLASRILDAKSKIEQIRAVLSSPAVTEQEVAQVASAILSLRR 660
Query: 661 TLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKREQFEKISSADPSGAFRMLST 720
TLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKREQFEKISSADPSGAFRMLST
Sbjct: 661 TLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKREQFEKISSADPSGAFRMLST 720
Query: 721 AYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGGGGTGSPKLVALRLEMSSLPDL 780
AYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGGGGTGSPKLVALRLEMSSLPDL
Sbjct: 721 AYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGGGGTGSPKLVALRLEMSSLPDL 780
Query: 781 TPTFNKLCGNSRQMACTPISCPGELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLR 840
TPTFNKLCGNSRQMACTPISCPGELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLR
Sbjct: 781 TPTFNKLCGNSRQMACTPISCPGELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLR 840
Query: 841 GFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLT 900
GFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLT
Sbjct: 841 GFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLT 900
Query: 901 DPDTDAATIQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARAR 960
DPDTDAATIQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARAR
Sbjct: 901 DPDTDAATIQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARAR 960
Query: 961 RLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQ 1020
RLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQ
Sbjct: 961 RLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQ 1020
Query: 1021 VLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFER 1080
VLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFER
Sbjct: 1021 VLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFER 1080
Query: 1081 IKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAI 1140
IKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAI
Sbjct: 1081 IKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAI 1140
Query: 1141 MLRSADLTGLEKRVEQIRDHINGRVLYYATCK 1172
MLRSADLTGLEKRVEQIRDHINGRVLYYATCK
Sbjct: 1141 MLRSADLTGLEKRVEQIRDHINGRVLYYATCK 1172
>gi|62868215 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 2418 bits (6266), Expect = 0.0
Identities = 1172/1172 (100%), Positives = 1172/1172 (100%)
Query: 1 MRPFFLLCFALPGLLHAQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYCTQYG 60
MRPFFLLCFALPGLLHAQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYCTQYG
Sbjct: 1 MRPFFLLCFALPGLLHAQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYCTQYG 60
Query: 61 EWQMKCCKCDSRQPHNYYSHRVENVASSSGPMRWWQSQNDVNPVSLQLDLDRRFQLQEVM 120
EWQMKCCKCDSRQPHNYYSHRVENVASSSGPMRWWQSQNDVNPVSLQLDLDRRFQLQEVM
Sbjct: 61 EWQMKCCKCDSRQPHNYYSHRVENVASSSGPMRWWQSQNDVNPVSLQLDLDRRFQLQEVM 120
Query: 121 MEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFPRVRQGRPQSWQDVRCQSLPQRP 180
MEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFPRVRQGRPQSWQDVRCQSLPQRP
Sbjct: 121 MEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFPRVRQGRPQSWQDVRCQSLPQRP 180
Query: 181 NARLNGGKVQLNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVPQRGYHPPSAYYA 240
NARLNGGKVQLNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVPQRGYHPPSAYYA
Sbjct: 181 NARLNGGKVQLNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVPQRGYHPPSAYYA 240
Query: 241 VSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNR 300
VSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNR
Sbjct: 241 VSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNR 300
Query: 301 PWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQL 360
PWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQL
Sbjct: 301 PWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQL 360
Query: 361 HYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGL 420
HYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGL
Sbjct: 361 HYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGL 420
Query: 421 TYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEP 480
TYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEP
Sbjct: 421 TYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEP 480
Query: 481 CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRG 540
CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRG
Sbjct: 481 CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRG 540
Query: 541 TEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDADLREQALRFG 600
TEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDADLREQALRFG
Sbjct: 541 TEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDADLREQALRFG 600
Query: 601 RLRNATASLWSGPGLEDRGLASRILDAKSKIEQIRAVLSSPAVTEQEVAQVASAILSLRR 660
RLRNATASLWSGPGLEDRGLASRILDAKSKIEQIRAVLSSPAVTEQEVAQVASAILSLRR
Sbjct: 601 RLRNATASLWSGPGLEDRGLASRILDAKSKIEQIRAVLSSPAVTEQEVAQVASAILSLRR 660
Query: 661 TLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKREQFEKISSADPSGAFRMLST 720
TLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKREQFEKISSADPSGAFRMLST
Sbjct: 661 TLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKREQFEKISSADPSGAFRMLST 720
Query: 721 AYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGGGGTGSPKLVALRLEMSSLPDL 780
AYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGGGGTGSPKLVALRLEMSSLPDL
Sbjct: 721 AYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGGGGTGSPKLVALRLEMSSLPDL 780
Query: 781 TPTFNKLCGNSRQMACTPISCPGELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLR 840
TPTFNKLCGNSRQMACTPISCPGELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLR
Sbjct: 781 TPTFNKLCGNSRQMACTPISCPGELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLR 840
Query: 841 GFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLT 900
GFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLT
Sbjct: 841 GFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLT 900
Query: 901 DPDTDAATIQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARAR 960
DPDTDAATIQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARAR
Sbjct: 901 DPDTDAATIQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARAR 960
Query: 961 RLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQ 1020
RLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQ
Sbjct: 961 RLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQ 1020
Query: 1021 VLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFER 1080
VLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFER
Sbjct: 1021 VLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFER 1080
Query: 1081 IKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAI 1140
IKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAI
Sbjct: 1081 IKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAI 1140
Query: 1141 MLRSADLTGLEKRVEQIRDHINGRVLYYATCK 1172
MLRSADLTGLEKRVEQIRDHINGRVLYYATCK
Sbjct: 1141 MLRSADLTGLEKRVEQIRDHINGRVLYYATCK 1172
>gi|189083719 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 2418 bits (6266), Expect = 0.0
Identities = 1172/1172 (100%), Positives = 1172/1172 (100%)
Query: 1 MRPFFLLCFALPGLLHAQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYCTQYG 60
MRPFFLLCFALPGLLHAQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYCTQYG
Sbjct: 1 MRPFFLLCFALPGLLHAQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYCTQYG 60
Query: 61 EWQMKCCKCDSRQPHNYYSHRVENVASSSGPMRWWQSQNDVNPVSLQLDLDRRFQLQEVM 120
EWQMKCCKCDSRQPHNYYSHRVENVASSSGPMRWWQSQNDVNPVSLQLDLDRRFQLQEVM
Sbjct: 61 EWQMKCCKCDSRQPHNYYSHRVENVASSSGPMRWWQSQNDVNPVSLQLDLDRRFQLQEVM 120
Query: 121 MEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFPRVRQGRPQSWQDVRCQSLPQRP 180
MEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFPRVRQGRPQSWQDVRCQSLPQRP
Sbjct: 121 MEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFPRVRQGRPQSWQDVRCQSLPQRP 180
Query: 181 NARLNGGKVQLNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVPQRGYHPPSAYYA 240
NARLNGGKVQLNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVPQRGYHPPSAYYA
Sbjct: 181 NARLNGGKVQLNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVPQRGYHPPSAYYA 240
Query: 241 VSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNR 300
VSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNR
Sbjct: 241 VSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNR 300
Query: 301 PWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQL 360
PWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQL
Sbjct: 301 PWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQL 360
Query: 361 HYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGL 420
HYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGL
Sbjct: 361 HYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGL 420
Query: 421 TYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEP 480
TYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEP
Sbjct: 421 TYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEP 480
Query: 481 CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRG 540
CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRG
Sbjct: 481 CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRG 540
Query: 541 TEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDADLREQALRFG 600
TEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDADLREQALRFG
Sbjct: 541 TEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDADLREQALRFG 600
Query: 601 RLRNATASLWSGPGLEDRGLASRILDAKSKIEQIRAVLSSPAVTEQEVAQVASAILSLRR 660
RLRNATASLWSGPGLEDRGLASRILDAKSKIEQIRAVLSSPAVTEQEVAQVASAILSLRR
Sbjct: 601 RLRNATASLWSGPGLEDRGLASRILDAKSKIEQIRAVLSSPAVTEQEVAQVASAILSLRR 660
Query: 661 TLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKREQFEKISSADPSGAFRMLST 720
TLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKREQFEKISSADPSGAFRMLST
Sbjct: 661 TLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKREQFEKISSADPSGAFRMLST 720
Query: 721 AYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGGGGTGSPKLVALRLEMSSLPDL 780
AYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGGGGTGSPKLVALRLEMSSLPDL
Sbjct: 721 AYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGGGGTGSPKLVALRLEMSSLPDL 780
Query: 781 TPTFNKLCGNSRQMACTPISCPGELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLR 840
TPTFNKLCGNSRQMACTPISCPGELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLR
Sbjct: 781 TPTFNKLCGNSRQMACTPISCPGELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLR 840
Query: 841 GFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLT 900
GFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLT
Sbjct: 841 GFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLT 900
Query: 901 DPDTDAATIQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARAR 960
DPDTDAATIQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARAR
Sbjct: 901 DPDTDAATIQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARAR 960
Query: 961 RLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQ 1020
RLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQ
Sbjct: 961 RLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQ 1020
Query: 1021 VLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFER 1080
VLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFER
Sbjct: 1021 VLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFER 1080
Query: 1081 IKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAI 1140
IKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAI
Sbjct: 1081 IKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAI 1140
Query: 1141 MLRSADLTGLEKRVEQIRDHINGRVLYYATCK 1172
MLRSADLTGLEKRVEQIRDHINGRVLYYATCK
Sbjct: 1141 MLRSADLTGLEKRVEQIRDHINGRVLYYATCK 1172
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 468 bits (1204), Expect = e-131
Identities = 231/514 (44%), Positives = 304/514 (59%), Gaps = 26/514 (5%)
Query: 21 CSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYC-TQYGEWQMKCCKCDSRQPH---- 75
CSRG+CYP GDLLVGR L ASSTCGL P+ YC + + + KC CDSR+P
Sbjct: 42 CSRGSCYPATGDLLVGRADRLTASSTCGLNGPQPYCIVSHLQDEKKCFLCDSRRPFSARD 101
Query: 76 NYYSHRVENVASSSGPMR---WWQSQNDVNPVSLQLDLDRRFQLQEVMMEFQGPMPAGML 132
N +SHR++NV +S P R WWQS+N + V++QLDL+ F ++M F+ PA ML
Sbjct: 102 NPHSHRIQNVVTSFAPQRRAAWWQSENGIPAVTIQLDLEAEFHFTHLIMTFKTFRPAAML 161
Query: 133 IERSSDFGKTWRVYQYLAADCTSTFPRVRQGRPQSWQDVRCQSLPQRPNARLNGGKVQLN 192
+ERS+DFG+TW VY+Y + DC + FP V P+ W DV C+S G +V
Sbjct: 162 VERSADFGRTWHVYRYFSYDCGADFPGVPLAPPRHWDDVVCESRYSEIEPSTEG-EVIYR 220
Query: 193 LMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVPQRGYHP-----PSAYYAVSQLRLQ 247
++D IP S +IQ + +ITNLRVN TRL + P YYA+ +L ++
Sbjct: 221 VLDPAIPIPDPYSSRIQNLLKITNLRVNLTRLHTLGDNLLDPRREIREKYYYALYELVVR 280
Query: 248 GSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEG 307
G+CFC+GHA CAP PGA A VH C+C+HNT G NCE+C FY + PWRPAE
Sbjct: 281 GNCFCYGHASECAPAPGAPAHAEG--MVHGACICKHNTRGLNCEQCQDFYRDLPWRPAED 338
Query: 308 QDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRR 367
+H C++C+C+GH+ +CHFD AV+ AS GGVCD C+ +T G++CE C+ ++R+
Sbjct: 339 GHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPT 398
Query: 368 PGASIQETCISCECDPDGAVPGAPCDP--------VTGQCVCKEHVQGERCDLCKPGFTG 419
C SC+CDP G+ G CD V+GQC CKEHV G RC C+ GF G
Sbjct: 399 KDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFG 458
Query: 420 LTYANPQGCHRCDCNILGS-RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASG-QG 477
L+ ++ GC RC CN G+ PCD SG C C V G CD+C P HW L+ G
Sbjct: 459 LSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLG 518
Query: 478 CEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMC 511
C PC CD +L PQC++ TGQC CR+ G C
Sbjct: 519 CRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRC 552
Score = 416 bits (1070), Expect = e-116
Identities = 300/978 (30%), Positives = 448/978 (45%), Gaps = 111/978 (11%)
Query: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
C C+GHAD C GA G C+ +T G +CERC ++ P P GQ
Sbjct: 877 CVCNGHADECNTHTGACLG------------CRDHTGGEHCERCIAGFHGDPRLPYGGQ- 923
Query: 310 AHECQRCDC-NGHSETCHFDPAVFAASQGAYGG--VCDNCRDHTEGKNCERCQLHYFRN- 365
C+ C C G HF + Q Y VC +CR G CE C +F +
Sbjct: 924 ---CRPCPCPEGPGSQRHF---ATSCHQDEYSQQIVC-HCRAGYTGLRCEACAPGHFGDP 976
Query: 366 RRPGASIQETCISCEC-------DPDGAVPGAPCDPVTGQCV-CKEHVQGERCDLCKPGF 417
RPG C CEC DPD CDP TGQC+ C H +G C CKPGF
Sbjct: 977 SRPGGR----CQLCECSGNIDPMDPDA------CDPHTGQCLRCLHHTEGPHCAHCKPGF 1026
Query: 418 TGLTYANPQGCHRCDCNILGSRRDM-------PCDEESGRCLCLPNVVGPKCDQCAPYHW 470
G A Q CHRC CN+LG+ CD SG+C CLPNV GP CD+CAP W
Sbjct: 1027 HG--QAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFW 1084
Query: 471 KLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATG 530
L SG GC+PCAC P + P CN+FTGQC CR GFGG CS +C + +GD
Sbjct: 1085 NLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCS-----ECQELHWGDPGLQ 1139
Query: 531 CRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDA 590
C ACDCD RG + P C + +G C CRPG++G RCDQC RG+ +P C CH CF +D
Sbjct: 1140 CHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHPCHACFGDWDR 1199
Query: 591 DLREQALRFGRLRNATASLWSGPGLEDRGLASRILDAKSKIEQIRAVLSSPAVTEQEVAQ 650
+++ A R RL L L S + K+ ++ ++ + + AQ
Sbjct: 1200 VVQDLAARTQRLEQRAQELQQTGVL--GAFESSFWHMQEKLGIVQGIVGARNTSAASTAQ 1257
Query: 651 VASAILSLRRT-------LQGLQLDL-PLEEETLSLPRDLESLDRSFNGLLTMYQRKREQ 702
+ A LRR L L+ DL +++E + L L+R L ++ +
Sbjct: 1258 LVEATEELRREIGEATEHLTQLEADLTDVQDENFNANHALSGLERDRLALNLTLRQLDQH 1317
Query: 703 FEKISSADPSGAFRMLSTAYEQSAQAAQQVSDSSRLL--------------DQLRDSRRE 748
+ + ++ GA+ + A+ QSA+A ++ + S+ + + L D+++E
Sbjct: 1318 LDLLKHSNFLGAYDSIRHAHSQSAEAERRANTSALAVPSPVSNSASARHRTEALMDAQKE 1377
Query: 749 ---AERLVRQAGGGGGTGSPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGEL 805
++ + Q G KL A +S LT +CG C C G
Sbjct: 1378 DFNSKHMANQRALG------KLSAHTHTLS----LTDINELVCGAPGDAPCATSPCGGAG 1427
Query: 806 CPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQ-----MIRAAE--E 858
C ++G RC G+ GA A + R A+LQR + R AE
Sbjct: 1428 CRDEDGQ---PRCGGL--SCNGAAATADLALGRARHTQAELQRALAEGGSILSRVAETRR 1482
Query: 859 SASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLA 918
AS+ Q AQ + +ASR Q+E+ + + LIQ V+DFL D +I+ V+ VL
Sbjct: 1483 QASEAQQRAQAALDKANASRGQVEQANQELQELIQSVKDFLNQEGADPDSIEMVATRVLE 1542
Query: 919 LWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAHAVEG 978
L +P + + I L +VD +L++T D+ RA +L +A ARS A +
Sbjct: 1543 LSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLLQDARRARSWAEDEKQ 1602
Query: 979 QVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGD 1038
+ E V L + A AQ ++G R + + +VQ+ + AE+ ++S ++
Sbjct: 1603 KAETVQAALEEAQRAQGIAQGAIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQ 1662
Query: 1039 FWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFE-RIKQKYAELK---DRLGQ 1094
+E L+ + A A++ A A +A A++ + +Y +K +R Q
Sbjct: 1663 LDALLEALKLKRAGNSLAASTAEETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKAQ 1722
Query: 1095 SSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRV 1154
+ + AR + ++ EA +L + + R++++E +A+ ++A L GLE R+
Sbjct: 1723 GVLAAQ--ARAEQLRDEARDLLQAAQDKLQRLQELEGTYEENERALESKAAQLDGLEARM 1780
Query: 1155 EQIRDHINGRVLYYATCK 1172
+ IN +V Y TC+
Sbjct: 1781 RSVLQAINLQVQIYNTCQ 1798
Score = 144 bits (362), Expect = 6e-34
Identities = 93/291 (31%), Positives = 126/291 (43%), Gaps = 49/291 (16%)
Query: 316 CDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHY----FRNRRPGAS 371
C C GH+ C P A ++G G C C+ +T G NCE+CQ Y +R G S
Sbjct: 283 CFCYGHASECAPAPGAPAHAEGMVHGACI-CKHNTRGLNCEQCQDFYRDLPWRPAEDGHS 341
Query: 372 IQETCISCECD--------------PDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGF 417
C CEC G V G CD C+ + G C+LC+P F
Sbjct: 342 --HACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDG------CQHNTAGRHCELCRPFF 393
Query: 418 ---TGLTYANPQGCHRCDCNILGSRRDMPCDEE--------SGRCLCLPNVVGPKCDQCA 466
+P C CDC+ +GS+ CD SG+C C +VVG +C QC
Sbjct: 394 YRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCR 453
Query: 467 PYHWKLASGQ--GCEPCACDPHNSL--SPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDR 522
+ L+ GC C C+ ++ S C+ +G C C+ G C +C
Sbjct: 454 DGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCD-----RCLPG 508
Query: 523 TYG--DVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY 571
+G GCR CDCD G P CD+ +G+C CR + G RC+Q Q GY
Sbjct: 509 HWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGY 559
Score = 133 bits (335), Expect = 9e-31
Identities = 77/215 (35%), Positives = 101/215 (46%), Gaps = 33/215 (15%)
Query: 372 IQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRC 431
I + C+C+P G++ + C+P GQC+CK V G RCDLC PG+ G P GC C
Sbjct: 776 IYNGALPCQCNPQGSL-SSECNPHGGQCLCKPGVVGRRCDLCAPGYYGF---GPTGCQAC 831
Query: 432 DCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSP 491
C+ G+ + C++ SG+CLC G +CD+C W S C PC C+ H +
Sbjct: 832 QCSHEGALSSL-CEKTSGQCLCRTGAFGLRCDRCQRGQWGFPS---CRPCVCNGH---AD 884
Query: 492 QCNQFTGQC-PCREGFGGLMCS--AAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDK 548
+CN TG C CR+ GG C A P YG CR C C EGPG +
Sbjct: 885 ECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGG---QCRPCPC----PEGPGSQR 937
Query: 549 ASGR------------CLCRPGLTGPRCDQCQRGY 571
C CR G TG RC+ C G+
Sbjct: 938 HFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGH 972
Score = 103 bits (256), Expect = 1e-21
Identities = 73/241 (30%), Positives = 98/241 (40%), Gaps = 45/241 (18%)
Query: 380 ECDPDGAVPGAPCDP---VTGQCVCKEHVQGERCDLCKPGFTGLTY-----ANPQGCHRC 431
EC P PGAP V G C+CK + +G C+ C+ + L + + C +C
Sbjct: 291 ECAP---APGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKC 347
Query: 432 DCN--ILGSRRDMPCDEESGRCL------CLPNVVGPKCDQCAPYHWK-----LASGQGC 478
+C+ DM SG C N G C+ C P+ ++ L C
Sbjct: 348 ECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVC 407
Query: 479 EPCACDPHNSLS---------PQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYG---D 526
C CDP S P +GQC C+E G C +QC D +G
Sbjct: 408 RSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRC-----QQCRDGFFGLSIS 462
Query: 527 VATGCRACDCDFRGTEGPG---CDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHP 583
GCR C C+ RGT PG CD SG C C+ +TG CD+C G+ + C P
Sbjct: 463 DRLGCRRCQCNARGTV-PGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRP 521
Query: 584 C 584
C
Sbjct: 522 C 522
Score = 102 bits (254), Expect = 2e-21
Identities = 59/150 (39%), Positives = 73/150 (48%), Gaps = 16/150 (10%)
Query: 444 CDEESGRCLCLPNVVGPKCDQCAPYHWKLAS--GQGCEPCACDPHNSLSPQCNQFTGQCP 501
C EE +P+ P + CAP L++ G PC C+P SLS +CN GQC
Sbjct: 749 CHEEG----LVPSKTSPS-EACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCL 803
Query: 502 CREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTG 561
C+ G G C C YG TGC+AC C G C+K SG+CLCR G G
Sbjct: 804 CKPGVVGRRCDL-----CAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFG 858
Query: 562 PRCDQCQRGYCNRYPVCVACHPCFQTYDAD 591
RCD+CQRG +P +C PC AD
Sbjct: 859 LRCDRCQRGQWG-FP---SCRPCVCNGHAD 884
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 447 bits (1150), Expect = e-125
Identities = 225/523 (43%), Positives = 306/523 (58%), Gaps = 25/523 (4%)
Query: 17 AQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYCT-QYGEWQMKCCKCDSRQPH 75
AQ C+RGAC+P GDLLVGR L ASSTCGL++ + YC Y E + KC CDSR P+
Sbjct: 19 AQDDCNRGACHPTTGDLLVGRNTQLMASSTCGLSRAQKYCILSYLEGEQKCFICDSRFPY 78
Query: 76 NYY----SHRVENVASSSGPMR---WWQSQNDVNPVSLQLDLDRRFQLQEVMMEFQGPMP 128
+ Y SH +ENV S P R WWQS+N ++ VS++LDL+ F+ +++ F+ P
Sbjct: 79 DPYDQPNSHTIENVIVSFEPDREKKWWQSENGLDHVSIRLDLEALFRFSHLILTFKTFRP 138
Query: 129 AGMLIERSSDFGKTWRVYQYLAADCTSTFPRVRQGRPQSWQDVRCQSLPQRPNARLNGGK 188
A ML+ERS+D+G W+V++Y A DC ++FP + G+ Q D+ C S GG+
Sbjct: 139 AAMLVERSTDYGHNWKVFKYFAKDCATSFPNITSGQAQGVGDIVCDSKYSDIEPS-TGGE 197
Query: 189 VQLNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVP------QRGYHPPSAYYAVS 242
V L ++D I S IQ++ +TNLR+NFT+L + ++ YYA+
Sbjct: 198 VVLKVLDPSFEIENPYSPYIQDLVTLTNLRINFTKLHTLGDALLGRRQNDSLDKYYYALY 257
Query: 243 QLRLQGSCFCHGHADRCAPKPGASAGP-STAVQVHDVCVCQHNTAGPNCERCAPFYNNRP 301
++ ++GSCFC+GHA C P S VH CVCQHNT GPNCERC F+ + P
Sbjct: 258 EMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAP 317
Query: 302 WRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLH 361
WRPA + C+ C CN HS CHFD + AS G GGVC++C+ +TEG++C+RC+
Sbjct: 318 WRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPL 377
Query: 362 YFRNRRPGASIQETCISCECDPDGAVPGAPC----DP----VTGQCVCKEHVQGERCDLC 413
++R+ S CI CECDPDG + G C DP V GQC+CKE+V+G +CD C
Sbjct: 378 FYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQC 437
Query: 414 KPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLA 473
KP GL+ +P GC CDCN LGS + CD ++G+CLCL V G C++C +W L
Sbjct: 438 KPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLG 497
Query: 474 SG-QGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAA 515
+ GC PC CD + S C+ GQC CR G CS A
Sbjct: 498 NHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPA 540
Score = 361 bits (927), Expect = 2e-99
Identities = 259/996 (26%), Positives = 429/996 (43%), Gaps = 125/996 (12%)
Query: 253 HG-HADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAH 311
HG H C P+ + + QV C C +G C+RC Y P
Sbjct: 812 HGCHPCHCHPQ---GSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFP---------- 858
Query: 312 ECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGAS 371
C C CN +E C DP G C NC T G+NCERC Y+ N G
Sbjct: 859 SCHPCPCNRFAELC--DPET---------GSCFNCGGFTTGRNCERCIDGYYGNPSSG-- 905
Query: 372 IQETCISCECDPDGA-------------------------------------------VP 388
+ C C C D + +
Sbjct: 906 --QPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRIS 963
Query: 389 GAPCDP-----------------VTGQCV-CKEHVQGERCDLCKPGFTGLTYANPQGCHR 430
GAPC P VTG+C+ C + QG C LCKPG G A Q C R
Sbjct: 964 GAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGS--ALNQTCRR 1021
Query: 431 CDCNILG-SRRDMP-------CDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCA 482
C C+ G S + P CD +G C CLPNV G CD+CA +W L G+GC+ C
Sbjct: 1022 CSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCD 1081
Query: 483 CDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTE 542
CDP S S C+Q TGQCPC+ G+GG CS +C + YGD C CDC+ GT+
Sbjct: 1082 CDPRTSQSSHCDQLTGQCPCKLGYGGKRCS-----ECQENYYGDPPGRCIPCDCNRAGTQ 1136
Query: 543 GPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDADLREQALRFGRL 602
P CD +G C CR G++G RCD+C RG+ +P C+ CH CF +D + + L
Sbjct: 1137 KPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPTCLQCHLCFDQWDHTISSLSKAVQGL 1196
Query: 603 RNATASLWSGPGLEDRGLASRILDA-----KSKIEQIRAVLSSPAVTEQEVAQVASAILS 657
A+ +ED+ + +A + + +I +L P + +V S
Sbjct: 1197 MRLAAN------MEDKRETLPVCEADFKDLRGNVSEIERILKHPVFPSGKFLKVKDYHDS 1250
Query: 658 LRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKREQFEKISSADPSGAFRM 717
+RR + L L E L +E + LL Q + + + +A + +
Sbjct: 1251 VRRQIMQLNEQLKAVYEFQDLKDTIERAKNEADLLLEDLQEEIDLQSSVLNASIADSSEN 1310
Query: 718 LSTAYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGGGGTGSPKLVALRLEMSSL 777
+ Y S+ A ++++++S ++ ++R + ++ T L RL+ +
Sbjct: 1311 IKKYYHISSSAEKKINETSSTINTSANTRNDLLTILDTL-----TSKGNLSLERLKQIKI 1365
Query: 778 PDLTPTFNKLCGNSRQMACTPISCPGELCPQDNG--TACGSRCRGVLPRAGGAFLMAGQV 835
PD+ K+CG+ + C P+ C G LC G G C G L + A A +
Sbjct: 1366 PDIQILNEKVCGDPGNVPCVPLPCGGALCTGRKGHRKCRGPGCHGSLTLSTNALQKAQEA 1425
Query: 836 AEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQV 895
+R + Q++ + I + E A +++A +L ++ R+Q + + L I++V
Sbjct: 1426 KSIIRNLDKQVRGLKNQIESISEQAEVSKNNALQLREKLGNIRNQSDSEEENINLFIKKV 1485
Query: 896 RDFLTDPDTDAATIQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQD 955
++FL + + I++V+ VL + LP S + ++ +IQ + ++ ++
Sbjct: 1486 KNFLLEENVPPEDIEKVANGVLDIHLPIPSQNLTDELVKIQKHMQLCEDYRTDENRLNEE 1545
Query: 956 IARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRV 1015
A++L +A+ A A+ + ++ + L+Q + A T+ + ++ I+ V
Sbjct: 1546 ADGAQKLLVKAKAAEKAANILL-NLDKTLNQLQQAQITQGRANSTITQLTANITKIKKNV 1604
Query: 1016 AEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQ 1075
+ + R K + KQ + L+ + ++ AV A+ AE A QA S +
Sbjct: 1605 LQAENQTREM-KSELELAKQRSGLEDGLSLLQTKLQRHQDHAVNAKVQAESAQHQAGSLE 1663
Query: 1076 EGFERIKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLR 1135
+ F +K++YA L+ + + + E +++ +K AE+L G+T + R+ D+E ++
Sbjct: 1664 KEFVELKKQYAILQRKTSTTGLTKETLGKVKQLKDAAEKLAGDTEAKIRRITDLERKIQD 1723
Query: 1136 GSQAIMLRSADLTGLEKRVEQIRDHINGRVLYYATC 1171
+ + ++ L LE +V I++ I + YA C
Sbjct: 1724 LNLSRQAKADQLRILEDQVVAIKNEIVEQEKKYARC 1759
Score = 149 bits (375), Expect = 2e-35
Identities = 96/291 (32%), Positives = 133/291 (45%), Gaps = 47/291 (16%)
Query: 316 CDCNGHSETCH----FDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNR--RPG 369
C CNGH+ C VF+ G G C C+ +T+G NCERC+ +F++ RP
Sbjct: 265 CFCNGHASECRPMQKMRGDVFSPP-GMVHGQCV-CQHNTDGPNCERCK-DFFQDAPWRPA 321
Query: 370 ASIQET-CISCECDP--------------DGAVPGAPCDPVTGQCVCKEHVQGERCDLCK 414
A +Q+ C SC C+ G + G C+ C+ + +G+ CD C+
Sbjct: 322 ADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCED------CQHNTEGQHCDRCR 375
Query: 415 PGFTG---LTYANPQGCHRCDCN--------ILGSRRDMPCDEESGRCLCLPNVVGPKCD 463
P F T ++P C C+C+ I S D +G+CLC NV G KCD
Sbjct: 376 PLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCD 435
Query: 464 QCAPYHWKLASGQ--GCEPCACDPHNSLS-PQCNQFTGQCPCREGFGGLMCSAAAIRQCP 520
QC P H+ L++ GC+PC C+P SL C+ TGQC C G C +
Sbjct: 436 QCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWG 495
Query: 521 DRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY 571
G+ GC CDCD G C +G+C CRP +TG C + GY
Sbjct: 496 ---LGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGY 543
Score = 114 bits (286), Expect = 4e-25
Identities = 96/332 (28%), Positives = 117/332 (35%), Gaps = 97/332 (29%)
Query: 325 CHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPD 384
CH +V +S GG C C+ G+ C+RC + G C C C P
Sbjct: 771 CHPQGSV-GSSCSRLGGQCQ-CKPLVVGRCCDRCSTGSYDLGHHG------CHPCHCHPQ 822
Query: 385 GAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPC 444
G+ CD VTGQC C V G RCD C G+ G CH C CN R C
Sbjct: 823 GS-KDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGF-----PSCHPCPCN----RFAELC 872
Query: 445 DEESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDPHNSLSPQCNQFTGQ--- 499
D E+G C C G C++C Y+ +SGQ C PC C P NQ+
Sbjct: 873 DPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPD----DPSSNQYFAHSCY 928
Query: 500 ---------CPCREGFGGLMC-------------SAAAIRQCPDRTYGDV--------AT 529
C C +G+ G C S A + C DV T
Sbjct: 929 QNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVT 988
Query: 530 G-----------------------------CRACDCDFRGTE----GPG-----CDKASG 551
G CR C C G PG CD +G
Sbjct: 989 GECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTG 1048
Query: 552 RCLCRPGLTGPRCDQCQRGYCNRYP--VCVAC 581
C C P +TG CD+C GY N P C +C
Sbjct: 1049 ACPCLPNVTGLACDRCADGYWNLVPGRGCQSC 1080
Score = 113 bits (282), Expect = 1e-24
Identities = 73/236 (30%), Positives = 107/236 (45%), Gaps = 26/236 (11%)
Query: 370 ASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCH 429
A + + ++C+C P G+V G+ C + GQC CK V G CD C G L + GCH
Sbjct: 760 AKLHDGAVACKCHPQGSV-GSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGH---HGCH 815
Query: 430 RCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSL 489
C C+ GS +D CD+ +G+C C V G +CD+C ++ S C PC C N
Sbjct: 816 PCHCHPQGS-KDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPS---CHPCPC---NRF 868
Query: 490 SPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATG--CRACDCD--------FR 539
+ C+ TG C GF + +C D YG+ ++G CR C C F
Sbjct: 869 AELCDPETGSCFNCGGF----TTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFA 924
Query: 540 GTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVA-CHPCFQTYDADLRE 594
+ + C C G TG +C +C G+ + A C PC + D+ +
Sbjct: 925 HSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTD 980
Score = 40.0 bits (92), Expect = 0.013
Identities = 26/91 (28%), Positives = 31/91 (34%), Gaps = 27/91 (29%)
Query: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
C+C G +CE C Y W G H C CDC+ GA
Sbjct: 475 CLCLSYVTGAHCEECTVGY----W--GLGNHLHGCSPCDCD---------------IGGA 513
Query: 339 YGGVCD------NCRDHTEGKNCERCQLHYF 363
Y VC CR H G++C YF
Sbjct: 514 YSNVCSPKNGQCECRPHVTGRSCSEPAPGYF 544
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 424 bits (1090), Expect = e-118
Identities = 218/517 (42%), Positives = 296/517 (57%), Gaps = 30/517 (5%)
Query: 21 CSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYC-TQYGEWQMKCCKCDSRQPH---- 75
C+ G+CYP GDLL+GR + L +STCGL KPE YC + + KC C+S+ P+
Sbjct: 30 CAEGSCYPATGDLLIGRAQKLSVTSTCGLHKPEPYCIVSHLQEDKKCFICNSQDPYHETL 89
Query: 76 NYYSHRVENVASSSGPMR---WWQSQNDVNPVSLQLDLDRRFQLQEVMMEFQGPMPAGML 132
N SH +ENV ++ P R WWQS+N V V++QLDL+ F ++M F+ PA ML
Sbjct: 90 NPDSHLIENVVTTFAPNRLKIWWQSENGVENVTIQLDLEAEFHFTHLIMTFKTFRPAAML 149
Query: 133 IERSSDFGKTWRVYQYLAADCTSTFPRVRQGRPQSWQDVRCQSLPQ--RPNARLNGGKVQ 190
IERSSDFGKTW VY+Y A DC ++FP + G + D+ C S P+ G+V
Sbjct: 150 IERSSDFGKTWGVYRYFAYDCEASFPGISTGPMKKVDDIICDSRYSDIEPSTE---GEVI 206
Query: 191 LNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPV-----PQRGYHPPSAYYAVSQLR 245
+D I S +IQ + +ITNLR+ F +L + R YYAV +
Sbjct: 207 FRALDPAFKIEDPYSPRIQNLLKITNLRIKFVKLHTLGDNLLDSRMEIREKYYYAVYDMV 266
Query: 246 LQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPA 305
++G+CFC+GHA CAP G + VH C+C+HNT G NCE C FY++ PWRPA
Sbjct: 267 VRGNCFCYGHASECAPVDGFNE--EVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPA 324
Query: 306 EGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRN 365
EG++++ C++C+CN HS +CHFD AV+ A+ GGVCD+C+ +T G+NCE+C+ Y+++
Sbjct: 325 EGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQH 384
Query: 366 RRPGASIQETCISCECDPDGAVPGAPCDPVT--------GQCVCKEHVQGERCDLCKPGF 417
C C CDP G+ CD T GQC CK +V+GE CD+CK GF
Sbjct: 385 PERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGF 444
Query: 418 TGLTYANPQGCHRCDCNILGS-RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASG- 475
L+ +P GC C CN LG+ PCD E+G C C V G CDQC P HW L++
Sbjct: 445 YDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDL 504
Query: 476 QGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCS 512
GC PC CD +L+ C +GQC CR G C+
Sbjct: 505 DGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCN 541
Score = 396 bits (1017), Expect = e-110
Identities = 272/964 (28%), Positives = 461/964 (47%), Gaps = 87/964 (9%)
Query: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERC-APFYNNRPWRPAEGQ 308
C C+GHAD C P G CQ T G NCERC A +Y + P G
Sbjct: 867 CQCNGHADDCDPVTGECLN------------CQDYTMGHNCERCLAGYYGD----PIIGS 910
Query: 309 DAHECQRCDC-------NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLH 361
H C+ C C + +C+ DP + VCD G C+ C
Sbjct: 911 GDH-CRPCPCPDGPDSGRQFARSCYQDPVTLQLAC-----VCD---PGYIGSRCDDCASG 961
Query: 362 YFRNRRPGASIQETCISCEC--DPDGAVPGAPCDPVTGQCV-CKEHVQGERCDLCKPGFT 418
YF N + + +C C+C + D P A CD TG+C+ C H +GE C C+ G+
Sbjct: 962 YFGNP---SEVGGSCQPCQCHNNIDTTDPEA-CDKETGRCLKCLYHTEGEHCQFCRFGYY 1017
Query: 419 GLTYANPQGCHRCDCNILGSRR------DMPCDEESGRCLCLPNVVGPKCDQCAPYHWKL 472
G A Q C +C CN LG+ + D CD+ +G+CLCLPNV+G CD+CAP W+L
Sbjct: 1018 G--DALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQL 1075
Query: 473 ASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCR 532
ASG GC+PC C+ +S P CN+FTGQC C GFGG CS +C + +GD CR
Sbjct: 1076 ASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCS-----ECQELFWGDPDVECR 1130
Query: 533 ACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDADL 592
ACDCD RG E P CD+++G+C+C G+ GPRCD+C RGY +P C CH CF +D +
Sbjct: 1131 ACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCHQCFALWDVII 1190
Query: 593 REQALRFGR-LRNATASLWSGPGLEDRGLASRILDAKSKIEQIRAVLS-SPAVTEQEVAQ 650
E R R L A A SG R + + K+ +I+ +L+ SPA + +
Sbjct: 1191 AELTNRTHRFLEKAKALKISGVIGPYRETVDSV---ERKVSEIKDILAQSPAA--EPLKN 1245
Query: 651 VASAILSLRRTLQGL-----QLDLPLEEETL---SLPRDLESLDRSFNGLLTMYQRKREQ 702
+ + + ++ + Q+++ L + T S ++L+SL L + EQ
Sbjct: 1246 IGNLFEEAEKLIKDVTEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVKELAEQ 1305
Query: 703 FEKISSADPSGAFRMLSTAYEQSAQAAQQVS-----------DSSRLLDQLRDSRREAER 751
E I ++D GA ++ ++ S +A ++V+ S+ + D++ D E E
Sbjct: 1306 LEFIKNSDIRGALDSITKYFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVMMERES 1365
Query: 752 LVRQAGGGGGTGSPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGELCPQDNG 811
++ + L L ++ SL DL+ CG +C+ C G C D G
Sbjct: 1366 QFKEK---QEEQARLLDELAGKLQSL-DLSAAAEMTCGTPPGASCSETECGGPNCRTDEG 1421
Query: 812 -TACGS-RCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQR 869
CG C G++ A A+ A + + + A++++ +M+ A+ A + + SA+
Sbjct: 1422 ERKCGGPGCGGLVTVAHNAWQKAMDLDQDVLSALAEVEQLSKMVSEAKLRADEAKQSAED 1481
Query: 870 LETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSATVL 929
+ + +A++ +M++ R LI+Q+R+FLT D +I+ V+ VL + +P+ +
Sbjct: 1482 ILLKTNATKEKMDKSNEELRNLIKQIRNFLTQDSADLDSIEAVANEVLKMEMPSTPQQLQ 1541
Query: 930 QKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQ 989
+I+ L V+++L + DIARA L EA+ A A V+ + V L +
Sbjct: 1542 NLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRASKSATDVKVTADMVKEALEE 1601
Query: 990 GTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQ 1049
A A+ ++ ++ Q+ + ++ +E+ + + ++++ + +EEL+ +
Sbjct: 1602 AEKAQVAAEKAIKQADEDIQGTQNLLTSIESETAASEETLFNASQRISELERNVEELKRK 1661
Query: 1050 ARQQGAEAVQAQQLAEGASEQALSAQEGFE-RIKQKYAELKDRLGQSSMLGEQGAR-IQS 1107
A Q EA +++ + A ++ + + +KY ++++ + + + R +
Sbjct: 1662 AAQNSGEAEYIEKVVYTVKQSAEDVKKTLDGELDEKYKKVENLIAKKTEESADARRKAEM 1721
Query: 1108 VKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQIRDHINGRVLY 1167
++ EA+ L + + +KD+E + + + ++ +L LE V + I+ +V
Sbjct: 1722 LQNEAKTLLAQANSKLQLLKDLERKYEDNQRYLEDKAQELARLEGEVRSLLKDISQKVAV 1781
Query: 1168 YATC 1171
Y+TC
Sbjct: 1782 YSTC 1785
Score = 139 bits (350), Expect = 2e-32
Identities = 81/233 (34%), Positives = 111/233 (47%), Gaps = 38/233 (16%)
Query: 370 ASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCH 429
A + +T ++CECDP G++ + CDP GQC C+ +V G C+ C PG G P GC
Sbjct: 764 ALLHQTGLACECDPQGSL-SSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGF---GPSGCK 819
Query: 430 RCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSL 489
C+C++ GS C+ +G+C C V +CD+C P HW S C+PC C+ H
Sbjct: 820 PCECHLQGSVNAF-CNPVTGQCHCFQGVYARQCDRCLPGHWGFPS---CQPCQCNGH--- 872
Query: 490 SPQCNQFTGQC-PCREGFGGLMCSAAAIRQCPDRTYGDVATG----CRACDCDFRGTEGP 544
+ C+ TG+C C++ G C +C YGD G CR C C +GP
Sbjct: 873 ADDCDPVTGECLNCQDYTMGHNC-----ERCLAGYYGDPIIGSGDHCRPCPC----PDGP 923
Query: 545 GCDKASGR------------CLCRPGLTGPRCDQCQRGYC-NRYPVCVACHPC 584
+ R C+C PG G RCD C GY N V +C PC
Sbjct: 924 DSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPC 976
Score = 132 bits (332), Expect = 2e-30
Identities = 89/289 (30%), Positives = 120/289 (41%), Gaps = 45/289 (15%)
Query: 316 CDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYF-----------R 364
C C GH+ C +G G C CR +T+G NCE C Y
Sbjct: 271 CFCYGHASECAPVDGFNEEVEGMVHGHC-MCRHNTKGLNCELCMDFYHDLPWRPAEGRNS 329
Query: 365 NRRPGASIQETCISCECD-----PDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGF-- 417
N + E ISC D G V G CD C+ + G C+ CKP +
Sbjct: 330 NACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDD------CQHNTMGRNCEQCKPFYYQ 383
Query: 418 -TGLTYANPQGCHRCDCNILGSRRDMPCDEES--------GRCLCLPNVVGPKCDQCAPY 468
+P C RC C+ GS+ + CD + G+C C NV G CD C
Sbjct: 384 HPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEG 443
Query: 469 HWKLASGQ--GCEPCACDPHNSL--SPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTY 524
+ L+S GC+ CAC+P ++ C+ TG C C+ G C QC +
Sbjct: 444 FYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCD-----QCLPEHW 498
Query: 525 G--DVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY 571
G + GCR CDCD G C SG+C CRP + G +C++ + GY
Sbjct: 499 GLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGY 547
Score = 123 bits (308), Expect = 1e-27
Identities = 102/335 (30%), Positives = 134/335 (40%), Gaps = 98/335 (29%)
Query: 325 CHFDPAVFAASQGAYGGVCD------NCRDHTEGKNCERCQLHYFRNRRPGASIQETCIS 378
C DP QG+ VCD CR + G+ C RC F G C
Sbjct: 773 CECDP------QGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSG------CKP 820
Query: 379 CECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC--HRCDCN-- 434
CEC G+V A C+PVTGQC C + V +CD C PG G P C H DC+
Sbjct: 821 CECHLQGSV-NAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPV 879
Query: 435 ---------------------------ILGSR---RDMPCDE--ESGR------------ 450
I+GS R PC + +SGR
Sbjct: 880 TGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVT 939
Query: 451 ----CLCLPNVVGPKCDQCAPYHWKLAS--GQGCEPCACDPHNSLS----PQCNQFTGQC 500
C+C P +G +CD CA ++ S G C+PC C HN++ C++ TG+C
Sbjct: 940 LQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQC--HNNIDTTDPEACDKETGRC 997
Query: 501 -PCREGFGGLMCSAAAIRQCPDRTYGD-VATGCRACDCDFRGT-------EGPGCDKASG 551
C G C + C YGD + CR C C++ GT CDKA+G
Sbjct: 998 LKCLYHTEGEHC-----QFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATG 1052
Query: 552 RCLCRPGLTGPRCDQCQRGYCNRYPVC--VACHPC 584
+CLC P + G CD+C N + + C PC
Sbjct: 1053 QCLCLPNVIGQNCDRCAP---NTWQLASGTGCDPC 1084
Score = 77.8 bits (190), Expect = 6e-14
Identities = 44/138 (31%), Positives = 65/138 (47%), Gaps = 12/138 (8%)
Query: 450 RCLCLPN----VVGPKCDQCAPYHWKLAS--GQGCEPCACDPHNSLSPQCNQFTGQCPCR 503
R CL N V P D C + +++ Q C CDP SLS C+ GQC CR
Sbjct: 736 RYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCR 795
Query: 504 EGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPR 563
G C+ +C T+G +GC+ C+C +G+ C+ +G+C C G+ +
Sbjct: 796 PNVVGRTCN-----RCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQ 850
Query: 564 CDQCQRGYCNRYPVCVAC 581
CD+C G+ +P C C
Sbjct: 851 CDRCLPGHWG-FPSCQPC 867
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 323 bits (829), Expect = 5e-88
Identities = 215/648 (33%), Positives = 304/648 (46%), Gaps = 105/648 (16%)
Query: 3 PFFLLCFALPGLLHAQQACSRG-ACYPPVGDLLVGRTRFLRASSTCGLTKP--------- 52
P L+ AL G A++ G + +PP +L G + AS+TCG P
Sbjct: 21 PLLLVGLALLGAARAREEAGGGFSLHPPYFNLAEGAR--IAASATCGEEAPARGSPRPTE 78
Query: 53 ETYC--------------TQYGEWQMKCCKCDSRQPHNYYSHRVENVASSSGPMRWWQSQ 98
+ YC T G++ C +S + H + + G RWWQS
Sbjct: 79 DLYCKLVGGPVAGGDPNQTIRGQYCDICTAANSNKAHPASN-------AIDGTERWWQSP 131
Query: 99 N-----DVNPVSLQLDLDRRFQLQEVMMEF-QGPMPAGMLIERSSDFGKTWRVYQYLAA- 151
+ N V++ LDL + F + V+++F P P ++ERS DFG+T++ +Q+ A+
Sbjct: 132 PLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQFFASS 191
Query: 152 --DCTSTFPRVRQGRPQSWQDVRCQSLPQRPNARLNGGKVQLNLMDLVSGIPATQ----S 205
DC F R C + R NG V + LV+G P S
Sbjct: 192 KRDCLERFGPQTLERITRDDAAICTTEYSRIVPLENGEIV----VSLVNGRPGAMNFSYS 247
Query: 206 QKIQEVGEITNLRVNFTR----LAPVPQRGYHPPSA----YYAVSQLRLQGSCFCHGHAD 257
++E + TN+R+ F R L + + P+ YY++ + + G C CHGHAD
Sbjct: 248 PLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCHGHAD 307
Query: 258 RCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCD 317
C K P+ ++ C CQHNT G C+RC P +N +PW+PA A+ECQ C+
Sbjct: 308 ACDAKD-----PTDPFRLQ--CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCN 360
Query: 318 CNGHSETCHFDPAV--FAASQ---GAY--GGVCDNCRDHTEGKNCERCQLHYFRNRRPGA 370
C GH+ C++DP V ASQ G Y GGVC +C+ HT G NCERC ++R+
Sbjct: 361 CYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPL 420
Query: 371 SIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGL--TYANPQGC 428
C C C+ D C+ +TG+C C+ + GERCD+C GFTG Y P
Sbjct: 421 DSPHVCRRCNCESD--FTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSS 478
Query: 429 H-------------RCDCNILGSRRDMPC--DEESGRCLCLPNVVGPKCDQCAPYHWKLA 473
+ CDC+ G++ + C D GRCLC PN G C+ CAP +
Sbjct: 479 NDTREQVLPAGQIVNCDCSAAGTQGN-ACRKDPRVGRCLCKPNFQGTHCELCAPGFY--- 534
Query: 474 SGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRA 533
G GC+PC C +C+ TGQC CR GF G C A P + + C+
Sbjct: 535 -GPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCA----PGYFHFPL---CQL 586
Query: 534 CDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVAC 581
C C GT GCD+A GRCLC+P GP CD+C+ GY + +P C AC
Sbjct: 587 CGCSPAGTLPEGCDEA-GRCLCQPEFAGPHCDRCRPGY-HGFPNCQAC 632
Score = 216 bits (550), Expect = 1e-55
Identities = 255/957 (26%), Positives = 362/957 (37%), Gaps = 176/957 (18%)
Query: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERC-APFYNNRPWRPAEG 307
C CHGH+DRC P G VCV CQHNT G +CERC A F ++R
Sbjct: 1864 CQCHGHSDRCLPGSG-------------VCVDCQHNTEGAHCERCQAGFVSSRD------ 1904
Query: 308 QDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDN------CRDHTEGKNCERCQLH 361
+ C C C P ++ A G V C+ G +CERC
Sbjct: 1905 DPSAPCVSCPC----------PLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPG 1954
Query: 362 YFRNRRPGASIQETCISCECDPDGA--VPGAPCDPVTGQCV-CKEHVQGERCDLCKPGFT 418
+F N + +C C+C +G + + CDP+TG C C H G RC++C PGF
Sbjct: 1955 FFGNP---LVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFY 2011
Query: 419 GLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGC 478
G P C RCDC G+ CD SG CLC V G +CD+C H+ GC
Sbjct: 2012 GNALL-PGNCTRCDCTPCGTEA---CDPHSGHCLCKAGVTGRRCDRCQEGHFGFDGCGGC 2067
Query: 479 EPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDF 538
PCAC P S +C+ +GQC CR G G C R+C +G GCR C C
Sbjct: 2068 RPCACGPAAEGS-ECHPQSGQCHCRPGTMGPQC-----RECAPGYWGLPEQGCRRCQC-- 2119
Query: 539 RGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPV----------CVACHPCFQTY 588
G CD +GRC C PGL+G RCD C + + + PV C C C
Sbjct: 2120 ---PGGRCDPHTGRCNCPPGLSGERCDTCSQQH--QVPVPGGPVGHSIHCEVCDHCVVLL 2174
Query: 589 DADLREQALRFGRLRNATASLWSGPGLEDRGLASRILDAKSKIEQIRAVLSSPAVTEQEV 648
DL R G L A G A R+ + I +++ L SP E
Sbjct: 2175 LDDLE----RAGALLPAIHEQLRGINASSMAWA-RLHRLNASIADLQSQLRSPLGPRHET 2229
Query: 649 AQVASAILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKREQFEKISS 708
AQ QL++ LE+++ SL +D L G R+Q
Sbjct: 2230 AQ---------------QLEV-LEQQSTSLGQDARRLGGQAVG-------TRDQ------ 2260
Query: 709 ADPSGAFRMLSTAYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAG--GGGGTGSPK 766
A + A + + LL +R R L+ Q G G +P
Sbjct: 2261 ------------ASQLLAGTEATLGHAKTLLAAIRAVDRTLSELMSQTGHLGLANASAPS 2308
Query: 767 LVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGELCPQDNGTACGSRCRGVLPRAG 826
L ++ + L +R + + EL A L
Sbjct: 2309 GEQLLRTLAEVERLLWEM-----RARDLGAPQAAAEAELAAAQRLLARVQEQLSSLWEEN 2363
Query: 827 GAFLMAGQVAEQLRGFNAQLQRTRQMIRAAEES---ASQIQSSAQRLETQVSASRSQMEE 883
A +A Q ++L A L R+ + A ++ A ++ S Q + + ++
Sbjct: 2364 QA--LATQTRDRLAQHEAGLMDLREALNRAVDATREAQELNSRNQERLEEALQRKQELSR 2421
Query: 884 DVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSA--TVLQKMNEI------ 935
D + + RD L ++ + E + L D A +LQ+M
Sbjct: 2422 DNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLLQRMQTFSPAGSK 2481
Query: 936 -------QAIAARLPNVDLVLSQTKQDIARARRLQ--AEAEEARSRAHAVEGQVEDVVGN 986
+A A +L + L LS D+ + R Q EA A SR ED G
Sbjct: 2482 LRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYSRILQAVQAAEDAAGQ 2541
Query: 987 LRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQ---LGDFWTRM 1043
ALQ+A T R Q V QQ+L + L +M ++ LG W +
Sbjct: 2542 ------ALQQADHTWATVVR-----QGLVDRAQQLLANSTALEEAMLQEQQRLGLVWAAL 2590
Query: 1044 EELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYAELKDRLGQSSMLGEQGA 1103
+ R Q R A+ Q + + A QA+ A + E K K A K A
Sbjct: 2591 QGARTQLRDVRAKKDQLEAHIQAA--QAMLAMDTDETSK-KIAHAK----------AVAA 2637
Query: 1104 RIQSVKTEAEELFGETMEMMDRMKDMELELLRG---SQAIMLRSADLTGLEKRVEQI 1157
Q T + E ++R + + E LRG QA++ ++ LEK + Q+
Sbjct: 2638 EAQDTATRVQSQLQAMQENVERWQG-QYEGLRGQDLGQAVLDAGHSVSTLEKTLPQL 2693
Score = 171 bits (434), Expect = 3e-42
Identities = 101/300 (33%), Positives = 132/300 (44%), Gaps = 45/300 (15%)
Query: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
C+CQ AGP+C+RC P Y+ P CQ C C DP
Sbjct: 605 CLCQPEFAGPHCDRCRPGYHGFP----------NCQACTC---------DPRGALDQLCG 645
Query: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQ 398
GG+C CR G C+ C PG +C+ C C +G++ A CDP +GQ
Sbjct: 646 AGGLC-RCRPGYTGTACQECS--------PGFHGFPSCVPCHCSAEGSLHAA-CDPRSGQ 695
Query: 399 CVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVV 458
C C+ V G RCD C PG Y CH + D E C+C +V
Sbjct: 696 CSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPV----DPALPEAQVPCMCRAHVE 751
Query: 459 GPKCDQCAPYHWKLASG--QGCEPCACDPHNSLS--PQCNQFTGQCPCREGFGGLMCSAA 514
GP CD+C P W L+ +GC C+CD +L +C TGQC C+ G C++
Sbjct: 752 GPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACAS- 810
Query: 515 AIRQCPDRTYG-DVAT--GCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY 571
C D +G D A GCR+C CD G G C+ +G C CRP GP C + R +
Sbjct: 811 ----CKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDH 866
Score = 127 bits (318), Expect = 8e-29
Identities = 70/195 (35%), Positives = 86/195 (44%), Gaps = 22/195 (11%)
Query: 379 CECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGS 438
C C GA G C+P GQC C HV G C C G+ G C CDC G+
Sbjct: 1438 CGCHEVGAT-GPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFP-----NCRPCDC---GA 1488
Query: 439 RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDP---HNSLSPQCNQ 495
R CDE +G+C+C P + P C C P + GCE C C P C+
Sbjct: 1489 RL---CDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDT 1545
Query: 496 FTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLC 555
+GQC CR G C C +G CR CDC GT CD +G+C C
Sbjct: 1546 DSGQCKCRPNVTGRRCDT-----CSPGFHG--YPRCRPCDCHEAGTAPGVCDPLTGQCYC 1598
Query: 556 RPGLTGPRCDQCQRG 570
+ + GP+CDQC G
Sbjct: 1599 KENVQGPKCDQCSLG 1613
Score = 114 bits (285), Expect = 5e-25
Identities = 83/271 (30%), Positives = 105/271 (38%), Gaps = 54/271 (19%)
Query: 248 GSCFCHG-----HADRCAPKPGASAGPSTAVQVHD-------------VCVCQHNTAGPN 289
G C C H DRC +PG P+ D +C C+ G
Sbjct: 603 GRCLCQPEFAGPHCDRC--RPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTA 660
Query: 290 CERCAPFYNNRP-----WRPAEGQDAHECQ----RCDCNGHSETCHFDPAVFAASQGAY- 339
C+ C+P ++ P AEG C +C C D V A Y
Sbjct: 661 CQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYC 720
Query: 340 -GGVCDN------------------CRDHTEGKNCERCQLHYFRNRRPGASIQETCISCE 380
G C CR H EG +C+RC+ ++ S E C C
Sbjct: 721 EAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGL---SPSNPEGCTRCS 777
Query: 381 CDPDGAVPG-APCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSR 439
CD G + G A C P TGQC CK HV G+ C CK GF GL A+ GC C C+I G
Sbjct: 778 CDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDI-GGA 836
Query: 440 RDMPCDEESGRCLCLPNVVGPKCDQCAPYHW 470
C+ +G C C PN GP C + A H+
Sbjct: 837 LGQSCEPRTGVCRCRPNTQGPTCSEPARDHY 867
Score = 104 bits (260), Expect = 4e-22
Identities = 67/199 (33%), Positives = 83/199 (41%), Gaps = 36/199 (18%)
Query: 248 GSCFCHGHA-----DRCAP--------KPGASAGPSTAVQVHDVCVCQHNTAGPNCERCA 294
G C CH H RCA +P G ++ C+C T P+C C
Sbjct: 1455 GQCPCHAHVIGRDCSRCATGYWGFPNCRP-CDCGARLCDELTGQCICPPRTIPPDCLLCQ 1513
Query: 295 PFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKN 354
P P G C+ C+C+G DP S G C CR + G+
Sbjct: 1514 P--QTFGCHPLVG-----CEECNCSGPGIQELTDPTCDTDS-----GQC-KCRPNVTGRR 1560
Query: 355 CERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCK 414
C+ C PG C C+C G PG CDP+TGQC CKE+VQG +CD C
Sbjct: 1561 CDTCS--------PGFHGYPRCRPCDCHEAGTAPGV-CDPLTGQCYCKENVQGPKCDQCS 1611
Query: 415 PGFTGLTYANPQGCHRCDC 433
G L ANP+GC RC C
Sbjct: 1612 LGTFSLDAANPKGCTRCFC 1630
Score = 94.0 bits (232), Expect = 8e-19
Identities = 55/173 (31%), Positives = 77/173 (44%), Gaps = 19/173 (10%)
Query: 413 CKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKL 472
C+ L+ G C C+ +G+ C+ G+C C +V+G C +CA +W
Sbjct: 1420 CRNAAASLSLFYNNGARPCGCHEVGATGPT-CEPFGGQCPCHAHVIGRDCSRCATGYWGF 1478
Query: 473 ASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYG-DVATGC 531
+ C PC C C++ TGQC C C C +T+G GC
Sbjct: 1479 PN---CRPCDCGAR-----LCDELTGQCICPPRTIPPDCLL-----CQPQTFGCHPLVGC 1525
Query: 532 RACDCDFRGTE---GPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVAC 581
C+C G + P CD SG+C CRP +TG RCD C G+ + YP C C
Sbjct: 1526 EECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGF-HGYPRCRPC 1577
Score = 36.2 bits (82), Expect = 0.19
Identities = 23/75 (30%), Positives = 32/75 (42%), Gaps = 8/75 (10%)
Query: 253 HGHADRCAPKPGASAG--PSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDA 310
HG+ RC P AG P + C C+ N GP C++C+ + +G
Sbjct: 1569 HGYP-RCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKG--- 1624
Query: 311 HECQRCDCNGHSETC 325
C RC C G +E C
Sbjct: 1625 --CTRCFCFGATERC 1637
>gi|93204871 netrin 4 [Homo sapiens]
Length = 628
Score = 305 bits (782), Expect = 1e-82
Identities = 181/467 (38%), Positives = 246/467 (52%), Gaps = 48/467 (10%)
Query: 11 LPGLLHAQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYC-----TQYGEWQMK 65
L G+ C + AC P +G+L +GR L A +TCG E YC T Q K
Sbjct: 20 LSGVAGVSSRCEK-ACNPRMGNLALGRK--LWADTTCGQNATELYCFYSENTDLTCRQPK 76
Query: 66 CCKCDSRQPHNYYSHRVENVASSSG--PMRWWQSQNDVNPVSLQLDLDRRFQLQEVMMEF 123
C KC++ PH +H +A SS P WWQS DV+ +QLDL+ F +++ F
Sbjct: 77 CDKCNAAYPH--LAHLPSAMADSSFRFPRTWWQSAEDVHREKIQLDLEAEFYFTHLIVMF 134
Query: 124 QGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFPR----VRQGRPQSWQDVRCQSLPQR 179
+ P PA M+++RS DFGKTW+ Y+Y A +C++TF V++G C S
Sbjct: 135 KSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATFGLEDDVVKKG-------AICTSKYSS 187
Query: 180 PNARLNGGKVQLNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVP-QRG--YHPPS 236
P GG+V + S K+QE +ITNLRV + P QR P
Sbjct: 188 PFP-CTGGEVIFKALSPPYDTENPYSAKVQEQLKITNLRVQLLKRQSCPCQRNDLNEEPQ 246
Query: 237 --AYYAVSQLRLQGSCFCHGHADRCAPKPGASA--GPSTAVQVHDVCVCQHNTAGPNCER 292
+YA+ ++GSCFC+GHAD+C P G P T VH C+C+HNTAG +C+
Sbjct: 247 HFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCMCKHNTAGSHCQH 306
Query: 293 CAPFYNNRPWRPAEGQDA--HECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHT 350
CAP YN+RPW A+G+ +EC+ C CNGH++TCHFD V+ AS GGVCD+C+ +T
Sbjct: 307 CAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNT 366
Query: 351 EGKNCERCQLHYFRNRRPGASIQETCISCECDPDGA--VPGAP---CDPVTGQCVCKEHV 405
EG+ C+RC+ ++R+ R S + C C C P G+ +P CDP G C CK V
Sbjct: 367 EGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGV 426
Query: 406 QGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCL 452
G RCD C G+ G GC CDC GS CD +G C+
Sbjct: 427 AGRRCDRCMVGYWGF---GDYGCRPCDC--AGS-----CDPITGDCI 463
Score = 91.3 bits (225), Expect = 5e-18
Identities = 62/218 (28%), Positives = 88/218 (40%), Gaps = 50/218 (22%)
Query: 316 CDCNGHSETC----HFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGAS 371
C CNGH++ C F P + G C C+ +T G +C+ C Y N RP +
Sbjct: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKC-MCKHNTAGSHCQHCAPLY--NDRPWEA 318
Query: 372 IQ------ETCISCEC--------------DPDGAVPGAPCDPVTGQCVCKEHVQGERCD 411
C +C+C + G G CD C+ + +G+ C
Sbjct: 319 ADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDD------CQHNTEGQYCQ 372
Query: 412 LCKPGF---TGLTYANPQGCHRCDCNILGSRRDMP------CDEESGRCLCLPNVVGPKC 462
CKPGF ++ P C C C+ +GS +P CD +G C C P V G +C
Sbjct: 373 RCKPGFYRDLRRPFSAPDACKPCSCHPVGSAV-LPANSVTFCDPSNGDCPCKPGVAGRRC 431
Query: 463 DQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQC 500
D+C +W GC PC C + C+ TG C
Sbjct: 432 DRCMVGYWGFGD-YGCRPCDC------AGSCDPITGDC 462
Score = 69.7 bits (169), Expect = 2e-11
Identities = 53/204 (25%), Positives = 77/204 (37%), Gaps = 47/204 (23%)
Query: 449 GRCLCLPNVVGPKCDQCAPYH----WKLASGQG-----CEPCACDPH--------NSLSP 491
G+C+C N G C CAP + W+ A G+ C C C+ H N
Sbjct: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 350
Query: 492 QCNQFTGQCP-CREGFGGLMCSAAAIRQCPDRTYGDVAT------GCRACDCDFRGT--- 541
N+ G C C+ G C ++C Y D+ C+ C C G+
Sbjct: 351 SGNRSGGVCDDCQHNTEGQYC-----QRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVL 405
Query: 542 ---EGPGCDKASGRCLCRPGLTGPRCDQCQRGY-------CNRYPVCVACHP----CFQT 587
CD ++G C C+PG+ G RCD+C GY C +C P C +
Sbjct: 406 PANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCDCAGSCDPITGDCISS 465
Query: 588 Y-DADLREQALRFGRLRNATASLW 610
+ D D + F + N + W
Sbjct: 466 HTDIDWYHEVPDFRPVHNKSEPAW 489
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 298 bits (762), Expect = 3e-80
Identities = 164/499 (32%), Positives = 253/499 (50%), Gaps = 38/499 (7%)
Query: 104 VSLQLDLDR-RFQLQEVMMEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFPRVRQ 162
V++ +DL+ ++Q+ ++++F P P + I+R + W +QY A +C F
Sbjct: 369 VTISVDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNC-GAFGMKNN 427
Query: 163 GRPQSWQDVRCQSLPQ-RPNARLNGGKVQLNLMDLVSGIPATQSQ-----KIQEVGEITN 216
G + V C L P +R G V +++ + +QE + T
Sbjct: 428 GDLEKPDSVNCLQLSNFTPYSR---GNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQ 484
Query: 217 LRVNFTRLAPVPQRGYHPPSAYYAVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVH 276
+R +F + + YYAV ++ + G C CHGHAD C +T+
Sbjct: 485 IRFHFHGQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADNC---------DTTSQPYR 535
Query: 277 DVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHF----DPAVF 332
+C + T G +C+RC P YN++P+R + A C+ C CN HS++CH+ DP F
Sbjct: 536 CLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPF 595
Query: 333 AASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGA-P 391
+G GGVCD+C +T G+NCE C+ ++FR S + C C+CD G G+
Sbjct: 596 EHFRGG-GGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSIL 654
Query: 392 CDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGS-RRDMPCDEESGR 450
CD + GQC CK HV G +C+ C+ GF L +P GC C+CN G+ D+ C + SG+
Sbjct: 655 CDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQ 714
Query: 451 CLCLPNVVGPKCDQCAPYHWKLA---SGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFG 507
C C NV+G +CD C + +K + GCEPC C+ H S++ CN +GQC C++
Sbjct: 715 CKCKANVIGLRCDHC-NFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAK 773
Query: 508 GLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGT-EGPGCDKASGRCLCRPGLTGPRCDQ 566
GL C C + YG T C+ACDCD G+ G C+ +G+C+C+P + G +C++
Sbjct: 774 GLQCDT-----CRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNK 828
Query: 567 CQRG-YCNRYPVCVACHPC 584
C G + R C PC
Sbjct: 829 CLEGNFYLRQNNSFLCLPC 847
Score = 179 bits (453), Expect = 2e-44
Identities = 110/336 (32%), Positives = 154/336 (45%), Gaps = 46/336 (13%)
Query: 264 GASAGPSTAVQVHDVCVCQHNTAGPNCERCAP-FYNNRPWRPAEGQDAHECQRCDCNGHS 322
G G Q+ C C+ + +G C +C FYN + D C C+CN
Sbjct: 647 GTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYN------LQELDPDGCSPCNCNTSG 700
Query: 323 E-----TCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQET-C 376
TCH + G C C+ + G C+ C + R S + C
Sbjct: 701 TVDGDITCHQN-----------SGQC-KCKANVIGLRCDHCNFGFKFLR----SFNDVGC 744
Query: 377 ISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNIL 436
C+C+ G+V C+P +GQC CK+ +G +CD C+ F GL N C CDC+
Sbjct: 745 EPCQCNLHGSV-NKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTN---CKACDCDTA 800
Query: 437 GSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQG--CEPCACDPHNSLSPQ-- 492
GS C+ ++G+C+C PNV G +C++C ++ L C PC CD +++
Sbjct: 801 GSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLL 860
Query: 493 CNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYG---DVATGCRACDCDFRGT-EGPGCDK 548
CN+ TGQCPC+ G GL C+ QC Y D C+ C+CD GT G CD
Sbjct: 861 CNKSTGQCPCKLGVTGLRCN-----QCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDP 915
Query: 549 ASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPC 584
SG+CLC P G RC+QCQ G+ C PC
Sbjct: 916 ISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPC 951
Score = 177 bits (449), Expect = 5e-44
Identities = 107/325 (32%), Positives = 150/325 (46%), Gaps = 45/325 (13%)
Query: 250 CFCHGHADR-CAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAP-FYNNRPWRPAEG 307
C HG ++ C P G C C+ G C+ C FY G
Sbjct: 749 CNLHGSVNKFCNPHSGQ-------------CECKKEAKGLQCDTCRENFY---------G 786
Query: 308 QDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRR 367
D C+ CDC +T P A G C C+ + EG+ C +C F R+
Sbjct: 787 LDVTNCKACDC----DTAGSLPGTVC---NAKTGQCI-CKPNVEGRQCNKCLEGNFYLRQ 838
Query: 368 PGASIQETCISCECDPDGAVPGAP-CDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQ 426
+ + C+ C CD G + G+ C+ TGQC CK V G RC+ C+P LT N Q
Sbjct: 839 NNSFL---CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQ 895
Query: 427 GCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDP 485
C C+C+ LG+ CD SG+CLC+PN G +C+QC P ++ + GC PC+C
Sbjct: 896 HCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHT 955
Query: 486 HNSLSPQCNQFTGQCPCRE-GFGGLMCSAAAIRQCPDRTYG-DVATG-CRACDCDFRGTE 542
+++ CN TGQC C++ G C QC D +G D TG C+ C+C G
Sbjct: 956 TGAVNHICNSLTGQCVCQDASIAGQRCD-----QCKDHYFGFDPQTGRCQPCNCHLSGAL 1010
Query: 543 GPGCDKASGRCLCRPGLTGPRCDQC 567
C +G+C C+ +TG +CD C
Sbjct: 1011 NETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 165 bits (418), Expect = 2e-40
Identities = 101/339 (29%), Positives = 153/339 (45%), Gaps = 36/339 (10%)
Query: 257 DRCAP----KPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHE 312
D C+P G G T Q C C+ N G C+ C N ++ +
Sbjct: 689 DGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHC-----NFGFKFLRSFNDVG 743
Query: 313 CQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASI 372
C+ C CN H F + G C+ C+ +G C+ C+ +++ G +
Sbjct: 744 CEPCQCNLHGSVNKFC--------NPHSGQCE-CKKEAKGLQCDTCRENFY-----GLDV 789
Query: 373 QETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCD 432
C +C+CD G++PG C+ TGQC+CK +V+G +C+ C G L N C C+
Sbjct: 790 TN-CKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCN 848
Query: 433 CNILGS-RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLA--SGQGCEPCACDPHNSL 489
C+ G+ + C++ +G+C C V G +C+QC P+ + L + Q C+ C CD +L
Sbjct: 849 CDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTL 908
Query: 490 SPQ-CNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDV--ATGCRACDCDFRGTEGPGC 546
C+ +GQC C G C+ QC Y ATGC C C G C
Sbjct: 909 PGTICDPISGQCLCVPNRQGRRCN-----QCQPGFYISPGNATGCLPCSCHTTGAVNHIC 963
Query: 547 DKASGRCLCRPG-LTGPRCDQCQRGYCNRYPVCVACHPC 584
+ +G+C+C+ + G RCDQC+ Y P C PC
Sbjct: 964 NSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPC 1002
Score = 91.3 bits (225), Expect = 5e-18
Identities = 60/199 (30%), Positives = 90/199 (45%), Gaps = 39/199 (19%)
Query: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
C C+ G C +C P N + CQ C+C+ S G
Sbjct: 868 CPCKLGVTGLRCNQCEPHRYNLTI-----DNFQHCQMCECD---------------SLGT 907
Query: 339 YGG-VCDN------CRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAP 391
G +CD C + +G+ C +CQ ++ + PG + C+ C C GAV
Sbjct: 908 LPGTICDPISGQCLCVPNRQGRRCNQCQPGFYIS--PGNATG--CLPCSCHTTGAVNHI- 962
Query: 392 CDPVTGQCVCKE-HVQGERCDLCKPGFTGLTYANPQG--CHRCDCNILGSRRDMPCDEES 448
C+ +TGQCVC++ + G+RCD CK + G +PQ C C+C++ G+ + C +
Sbjct: 963 CNSLTGQCVCQDASIAGQRCDQCKDHYFGF---DPQTGRCQPCNCHLSGALNET-CHLVT 1018
Query: 449 GRCLCLPNVVGPKCDQCAP 467
G+C C V G KCD C P
Sbjct: 1019 GQCFCKQFVTGSKCDACVP 1037
Score = 72.0 bits (175), Expect = 3e-12
Identities = 52/182 (28%), Positives = 73/182 (40%), Gaps = 40/182 (21%)
Query: 257 DRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRC 316
D PG P + C+C N G C +C P + P +A C C
Sbjct: 903 DSLGTLPGTICDP-----ISGQCLCVPNRQGRRCNQCQPGFYISPG------NATGCLPC 951
Query: 317 DCNGHSETCHFDPAVFAASQGAYGGVCDN------CRDHT-EGKNCERCQLHYFRNRRPG 369
C+ + GA +C++ C+D + G+ C++C+ HYF G
Sbjct: 952 SCH---------------TTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYF-----G 991
Query: 370 ASIQE-TCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428
Q C C C GA+ C VTGQC CK+ V G +CD C P + L N GC
Sbjct: 992 FDPQTGRCQPCNCHLSGAL-NETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGC 1050
Query: 429 HR 430
+
Sbjct: 1051 SK 1052
>gi|219842259 usherin isoform A [Homo sapiens]
Length = 1546
Score = 298 bits (762), Expect = 3e-80
Identities = 164/499 (32%), Positives = 253/499 (50%), Gaps = 38/499 (7%)
Query: 104 VSLQLDLDR-RFQLQEVMMEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFPRVRQ 162
V++ +DL+ ++Q+ ++++F P P + I+R + W +QY A +C F
Sbjct: 369 VTISVDLENGQYQVFYIIIQFFSPQPTEIRIQRKKENSLDWEDWQYFARNC-GAFGMKNN 427
Query: 163 GRPQSWQDVRCQSLPQ-RPNARLNGGKVQLNLMDLVSGIPATQSQ-----KIQEVGEITN 216
G + V C L P +R G V +++ + +QE + T
Sbjct: 428 GDLEKPDSVNCLQLSNFTPYSR---GNVTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQ 484
Query: 217 LRVNFTRLAPVPQRGYHPPSAYYAVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVH 276
+R +F + + YYAV ++ + G C CHGHAD C +T+
Sbjct: 485 IRFHFHGQYYTTETAVNLRHRYYAVDEITISGRCQCHGHADNC---------DTTSQPYR 535
Query: 277 DVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHF----DPAVF 332
+C + T G +C+RC P YN++P+R + A C+ C CN HS++CH+ DP F
Sbjct: 536 CLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPF 595
Query: 333 AASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGA-P 391
+G GGVCD+C +T G+NCE C+ ++FR S + C C+CD G G+
Sbjct: 596 EHFRGG-GGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSIL 654
Query: 392 CDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGS-RRDMPCDEESGR 450
CD + GQC CK HV G +C+ C+ GF L +P GC C+CN G+ D+ C + SG+
Sbjct: 655 CDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQ 714
Query: 451 CLCLPNVVGPKCDQCAPYHWKLA---SGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFG 507
C C NV+G +CD C + +K + GCEPC C+ H S++ CN +GQC C++
Sbjct: 715 CKCKANVIGLRCDHC-NFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAK 773
Query: 508 GLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGT-EGPGCDKASGRCLCRPGLTGPRCDQ 566
GL C C + YG T C+ACDCD G+ G C+ +G+C+C+P + G +C++
Sbjct: 774 GLQCDT-----CRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNK 828
Query: 567 CQRG-YCNRYPVCVACHPC 584
C G + R C PC
Sbjct: 829 CLEGNFYLRQNNSFLCLPC 847
Score = 179 bits (453), Expect = 2e-44
Identities = 110/336 (32%), Positives = 154/336 (45%), Gaps = 46/336 (13%)
Query: 264 GASAGPSTAVQVHDVCVCQHNTAGPNCERCAP-FYNNRPWRPAEGQDAHECQRCDCNGHS 322
G G Q+ C C+ + +G C +C FYN + D C C+CN
Sbjct: 647 GTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYN------LQELDPDGCSPCNCNTSG 700
Query: 323 E-----TCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQET-C 376
TCH + G C C+ + G C+ C + R S + C
Sbjct: 701 TVDGDITCHQN-----------SGQC-KCKANVIGLRCDHCNFGFKFLR----SFNDVGC 744
Query: 377 ISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNIL 436
C+C+ G+V C+P +GQC CK+ +G +CD C+ F GL N C CDC+
Sbjct: 745 EPCQCNLHGSV-NKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTN---CKACDCDTA 800
Query: 437 GSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQG--CEPCACDPHNSLSPQ-- 492
GS C+ ++G+C+C PNV G +C++C ++ L C PC CD +++
Sbjct: 801 GSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLL 860
Query: 493 CNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYG---DVATGCRACDCDFRGT-EGPGCDK 548
CN+ TGQCPC+ G GL C+ QC Y D C+ C+CD GT G CD
Sbjct: 861 CNKSTGQCPCKLGVTGLRCN-----QCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDP 915
Query: 549 ASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPC 584
SG+CLC P G RC+QCQ G+ C PC
Sbjct: 916 ISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPC 951
Score = 177 bits (449), Expect = 5e-44
Identities = 107/325 (32%), Positives = 150/325 (46%), Gaps = 45/325 (13%)
Query: 250 CFCHGHADR-CAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAP-FYNNRPWRPAEG 307
C HG ++ C P G C C+ G C+ C FY G
Sbjct: 749 CNLHGSVNKFCNPHSGQ-------------CECKKEAKGLQCDTCRENFY---------G 786
Query: 308 QDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRR 367
D C+ CDC +T P A G C C+ + EG+ C +C F R+
Sbjct: 787 LDVTNCKACDC----DTAGSLPGTVC---NAKTGQCI-CKPNVEGRQCNKCLEGNFYLRQ 838
Query: 368 PGASIQETCISCECDPDGAVPGAP-CDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQ 426
+ + C+ C CD G + G+ C+ TGQC CK V G RC+ C+P LT N Q
Sbjct: 839 NNSFL---CLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQ 895
Query: 427 GCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDP 485
C C+C+ LG+ CD SG+CLC+PN G +C+QC P ++ + GC PC+C
Sbjct: 896 HCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHT 955
Query: 486 HNSLSPQCNQFTGQCPCRE-GFGGLMCSAAAIRQCPDRTYG-DVATG-CRACDCDFRGTE 542
+++ CN TGQC C++ G C QC D +G D TG C+ C+C G
Sbjct: 956 TGAVNHICNSLTGQCVCQDASIAGQRCD-----QCKDHYFGFDPQTGRCQPCNCHLSGAL 1010
Query: 543 GPGCDKASGRCLCRPGLTGPRCDQC 567
C +G+C C+ +TG +CD C
Sbjct: 1011 NETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 165 bits (418), Expect = 2e-40
Identities = 101/339 (29%), Positives = 153/339 (45%), Gaps = 36/339 (10%)
Query: 257 DRCAP----KPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHE 312
D C+P G G T Q C C+ N G C+ C N ++ +
Sbjct: 689 DGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHC-----NFGFKFLRSFNDVG 743
Query: 313 CQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASI 372
C+ C CN H F + G C+ C+ +G C+ C+ +++ G +
Sbjct: 744 CEPCQCNLHGSVNKFC--------NPHSGQCE-CKKEAKGLQCDTCRENFY-----GLDV 789
Query: 373 QETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCD 432
C +C+CD G++PG C+ TGQC+CK +V+G +C+ C G L N C C+
Sbjct: 790 TN-CKACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCN 848
Query: 433 CNILGS-RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLA--SGQGCEPCACDPHNSL 489
C+ G+ + C++ +G+C C V G +C+QC P+ + L + Q C+ C CD +L
Sbjct: 849 CDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTL 908
Query: 490 SPQ-CNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDV--ATGCRACDCDFRGTEGPGC 546
C+ +GQC C G C+ QC Y ATGC C C G C
Sbjct: 909 PGTICDPISGQCLCVPNRQGRRCN-----QCQPGFYISPGNATGCLPCSCHTTGAVNHIC 963
Query: 547 DKASGRCLCRPG-LTGPRCDQCQRGYCNRYPVCVACHPC 584
+ +G+C+C+ + G RCDQC+ Y P C PC
Sbjct: 964 NSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPC 1002
Score = 91.3 bits (225), Expect = 5e-18
Identities = 60/199 (30%), Positives = 90/199 (45%), Gaps = 39/199 (19%)
Query: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
C C+ G C +C P N + CQ C+C+ S G
Sbjct: 868 CPCKLGVTGLRCNQCEPHRYNLTI-----DNFQHCQMCECD---------------SLGT 907
Query: 339 YGG-VCDN------CRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAP 391
G +CD C + +G+ C +CQ ++ + PG + C+ C C GAV
Sbjct: 908 LPGTICDPISGQCLCVPNRQGRRCNQCQPGFYIS--PGNATG--CLPCSCHTTGAVNHI- 962
Query: 392 CDPVTGQCVCKE-HVQGERCDLCKPGFTGLTYANPQG--CHRCDCNILGSRRDMPCDEES 448
C+ +TGQCVC++ + G+RCD CK + G +PQ C C+C++ G+ + C +
Sbjct: 963 CNSLTGQCVCQDASIAGQRCDQCKDHYFGF---DPQTGRCQPCNCHLSGALNET-CHLVT 1018
Query: 449 GRCLCLPNVVGPKCDQCAP 467
G+C C V G KCD C P
Sbjct: 1019 GQCFCKQFVTGSKCDACVP 1037
Score = 72.0 bits (175), Expect = 3e-12
Identities = 52/182 (28%), Positives = 73/182 (40%), Gaps = 40/182 (21%)
Query: 257 DRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRC 316
D PG P + C+C N G C +C P + P +A C C
Sbjct: 903 DSLGTLPGTICDP-----ISGQCLCVPNRQGRRCNQCQPGFYISPG------NATGCLPC 951
Query: 317 DCNGHSETCHFDPAVFAASQGAYGGVCDN------CRDHT-EGKNCERCQLHYFRNRRPG 369
C+ + GA +C++ C+D + G+ C++C+ HYF G
Sbjct: 952 SCH---------------TTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYF-----G 991
Query: 370 ASIQE-TCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428
Q C C C GA+ C VTGQC CK+ V G +CD C P + L N GC
Sbjct: 992 FDPQTGRCQPCNCHLSGAL-NETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGC 1050
Query: 429 HR 430
+
Sbjct: 1051 SK 1052
>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
Length = 1609
Score = 276 bits (707), Expect = 6e-74
Identities = 161/467 (34%), Positives = 237/467 (50%), Gaps = 48/467 (10%)
Query: 43 ASSTCGLTKPETYCTQYGEWQM--KCCKCDSRQPHNYYSHRVENVASSSGPMRWWQSQND 100
A++TCG T PE YC Q G + C CD+ QPH + ++ WWQSQ
Sbjct: 65 ATNTCG-TPPEEYCVQTGVTGVTKSCHLCDAGQPHLQHGAAFLTDYNNQADTTWWQSQTM 123
Query: 101 V------NPVSLQLDLDRRFQLQEVMMEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCT 154
+ + ++L L L + F + V ++F P I + + W YQY + C
Sbjct: 124 LAGVQYPSSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIPYQYYSGSCE 183
Query: 155 STFPRVRQGRPQSWQDVRCQSLPQRPN--ARLNGGKVQLNLMDLVSGIPAT----QSQKI 208
+T+ + +G ++ D + + + L GG V + ++ G P+ S +
Sbjct: 184 NTYSKANRGFIRTGGDEQQALCTDEFSDISPLTGGNVAFSTLE---GRPSAYNFDNSPVL 240
Query: 209 QEVGEITNLRVNFTRLAPVPQRGYHPP----SAYYAVSQLRLQGSCFCHGHADRCAPKPG 264
QE T++RV RL ++ P S YYA+S + G C C+GHA C
Sbjct: 241 QEWVTATDIRVTLNRLNTFGDEVFNDPKVLKSYYYAISDFAVGGRCKCNGHASECMKNEF 300
Query: 265 ASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSET 324
VC C+HNT G +CE+C PF+N+RPWR A + A EC CDCNG S+
Sbjct: 301 DKL----------VCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQE 350
Query: 325 CHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPD 384
C+FDP ++ ++ +GG C NC+D+T+G +CERC+ ++FR E C SC C P
Sbjct: 351 CYFDPELYRST--GHGGHCTNCQDNTDGAHCERCRENFFR-----LGNNEACSSCHCSPV 403
Query: 385 GAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPC 444
G++ CD G+C CK V G++CD C+PGF LT A GC C C+ GS + C
Sbjct: 404 GSL-STQCDSY-GRCSCKPGVMGDKCDRCQPGFHSLTEA---GCRPCSCDPSGSIDE--C 456
Query: 445 DEESGRCLCLPNVVGPKCDQCAPYHWKLASG--QGCEPCACDPHNSL 489
+ E+GRC+C NV G C++C P + L S +GC PC C H+S+
Sbjct: 457 NIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSV 503
Score = 253 bits (647), Expect = 6e-67
Identities = 228/943 (24%), Positives = 387/943 (41%), Gaps = 108/943 (11%)
Query: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
C C+GH++ C P+ G VC C+ NTAGP+CE+C+ Y + +
Sbjct: 724 CACNGHSETCDPETG-------------VCNCRDNTAGPHCEKCSDGY----YGDSTAGT 766
Query: 310 AHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPG 369
+ +CQ C C G S +C P VC NC T GK CE C YF +
Sbjct: 767 SSDCQPCPCPGGS-SCAVVPKTKEV-------VCTNCPTGTTGKRCELCDDGYFGDPLGR 818
Query: 370 ASIQETCISCECDPDGAVPGAP--CDPVTGQCV-CKEHVQGERCDLCKPGFTGLTYA-NP 425
C C+C D P A C+ +TG+C+ C + G CD CK GF G A NP
Sbjct: 819 NGPVRLCRLCQCS-DNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNP 877
Query: 426 QG-CHRCDCNILGS-RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCAC 483
C C+CN+ G+ ++ C+ +G+C CLP+V G C C P + L SGQGCE C C
Sbjct: 878 ADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSGQGCERCDC 937
Query: 484 DPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEG 543
S + QC+ TGQC C+ G G C +C +G GC+ CDC G+
Sbjct: 938 HALGSTNGQCDIRTGQCECQPGITGQHC-----ERCEVNHFGFGPEGCKPCDCHPEGSLS 992
Query: 544 PGCDKASGRCLCRPGLTGPRCDQCQRGY-CNR-YPVCVACHPCFQTYDADLREQALRFGR 601
C K GRC CR G G RCDQC+ Y NR +P C C C++ + + ++
Sbjct: 993 LQC-KDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQECPACYRLVKDKVADHRVKLQE 1051
Query: 602 LRNATASLWSGPGL-EDRGLASRILDAKSKI-EQIRAVLSSPAVTEQEVAQVASAILSLR 659
L + A+L +G + D+ R+ +A+ ++ + +R V + + ++ +L
Sbjct: 1052 LESLIANLGTGDEMVTDQAFEDRLKEAEREVMDLLREAQDVKDVDQNLMDRLQRVNNTLS 1111
Query: 660 RTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQRKREQ----------FEKISSA 709
+ LQ EET +L + + L+ + R+ E+ + S+
Sbjct: 1112 SQISRLQNIRNTIEETGNLAEQARAHVENTERLIEIASRELEKAKVAAANVSVTQPESTG 1171
Query: 710 DPSGAFRMLSTAYEQSAQAAQQVSDSSRLLDQLRDSRREAERLVRQAGGGGGTGSPKLVA 769
DP+ + A + + + Q+ D R+ D+ EA L+ + G + ++
Sbjct: 1172 DPNNMTLLAEEARKLAERHKQEADDIVRVAKTANDTSTEAYNLLLRTLAGENQTAFEIEE 1231
Query: 770 LRLEMSSLPDLTPTFNKLCGNSRQ-------MACTPISCPGELCPQDNGTACGSRCRGVL 822
L + +++ K + A + +L P D+ T + +
Sbjct: 1232 LNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLSPLDSET-LENEANNIK 1290
Query: 823 PRAGGAFLMAGQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSASRSQME 882
A + Q + ++ ++ E Q +A +L + A+++ E
Sbjct: 1291 MEAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAE 1350
Query: 883 EDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSATVLQK-MNEIQAIAAR 941
E ++ R +Q+ D L + +++ V D+ T ++ + +I AI
Sbjct: 1351 EAAKKGRDTLQEANDILNN-------LKDFDRRV------NDNKTAAEEALRKIPAINQT 1397
Query: 942 LPNVDLVLSQTKQDIARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTM 1001
+ + + +Q + A A+A EA+++AH E R + + A T
Sbjct: 1398 ITEANEKTREAQQALGSA---AADATEAKNKAHEAE----------RIASAVQKNATSTK 1444
Query: 1002 QGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQARQQGAEAVQAQ 1061
R+ + D + V +M KQL + ++ + A Q A A
Sbjct: 1445 AEAERTFAEVTD-----------LDNEVNNMLKQLQEAEKELKRKQDDADQDMMMAGMAS 1493
Query: 1062 QLAEGASEQALSAQEGFERIKQKYAELKDRLGQ-----SSMLGEQGARIQSVKTEAEELF 1116
Q A+ A A A+ + +L ++LGQ + L E + K E
Sbjct: 1494 QAAQEAEINARKAKNSVTSLLSIINDLLEQLGQLDTVDLNKLNEIEGTLNKAKDEM---- 1549
Query: 1117 GETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQIRD 1159
+ ++ ++ D+E E + AIM + D+ + K + + D
Sbjct: 1550 -KVSDLDRKVSDLENEAKKQEAAIMDYNRDIEEIMKDIRNLED 1591
Score = 103 bits (258), Expect = 7e-22
Identities = 62/201 (30%), Positives = 89/201 (44%), Gaps = 23/201 (11%)
Query: 399 CVCKEHVQGERCDLCKPGFTG-----LTYANPQGCHRCDCNILGSRRDMPCDEE------ 447
C CK + G C+ C P F T + C CDCN G ++ D E
Sbjct: 305 CNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCN--GRSQECYFDPELYRSTG 362
Query: 448 -SGRCL-CLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREG 505
G C C N G C++C ++L + + C C C P SLS QC+ + G+C C+ G
Sbjct: 363 HGGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPVGSLSTQCDSY-GRCSCKPG 421
Query: 506 FGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCD 565
G C +C + GCR C CD G+ C+ +GRC+C+ + G C+
Sbjct: 422 VMGDKCD-----RCQPGFHSLTEAGCRPCSCDPSGSIDE-CNIETGRCVCKDNVEGFNCE 475
Query: 566 QCQRGYCN-RYPVCVACHPCF 585
+C+ G+ N C PCF
Sbjct: 476 RCKPGFFNLESSNPRGCTPCF 496
Score = 45.8 bits (107), Expect = 2e-04
Identities = 31/97 (31%), Positives = 39/97 (40%), Gaps = 25/97 (25%)
Query: 248 GSCFCH-----GHADRCAP----------KPGASAGPSTAVQVHDV----CVCQHNTAGP 288
G C C DRC P +P S PS ++ ++ CVC+ N G
Sbjct: 414 GRCSCKPGVMGDKCDRCQPGFHSLTEAGCRP-CSCDPSGSIDECNIETGRCVCKDNVEGF 472
Query: 289 NCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETC 325
NCERC P + N E + C C C GHS C
Sbjct: 473 NCERCKPGFFN-----LESSNPRGCTPCFCFGHSSVC 504
>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
Length = 3333
Score = 269 bits (688), Expect = 1e-71
Identities = 186/593 (31%), Positives = 262/593 (44%), Gaps = 97/593 (16%)
Query: 43 ASSTCG-------LTKPETYCTQYG-----------EWQMKCCKCDSRQPHNYYSHRVEN 84
A++TCG +PE YC G + Q C C+S P +H V N
Sbjct: 62 ATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQF-CDYCNSEDPRK--AHPVTN 118
Query: 85 VASSSGPMRWWQSQ-----NDVNPVSLQLDLDRRFQLQEVMMEF-QGPMPAGMLIERSSD 138
G RWWQS N V+L LDL + F + ++++F P P ++ERS D
Sbjct: 119 AID--GSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVD 176
Query: 139 FGKTWRVYQYLA---ADCTSTFPRVRQGRPQSWQDVRCQSLPQRPNARLNGGKVQLNLMD 195
FG T+ +QY A DC F R DV C + R NG V +
Sbjct: 177 FGSTYSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVV----VS 232
Query: 196 LVSGIPA----TQSQKIQEVGEITNLRVNFTR----LAPVPQRGYHPPSA----YYAVSQ 243
L++G P T S ++E + TN+R+ F R L + + P+ YY++
Sbjct: 233 LINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKD 292
Query: 244 LRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWR 303
+ + G C C+GHA+ C P + C CQH+T G C+RC YN R WR
Sbjct: 293 ISIGGQCVCNGHAEVCNIN-----NPEKLFR----CECQHHTCGETCDRCCTGYNQRRWR 343
Query: 304 PAEGQDAHECQRCDCNGHSETCHFDPAV-----FAASQGAY--GGVCDNCRDHTEGKNCE 356
PA + +HEC+ C+C+GH+ C++DP V +QG Y GGVC NC+ +T G NCE
Sbjct: 344 PAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCE 403
Query: 357 RCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPG 416
+C Y+R + CI C CDP+ A C+ +G+C CK + G+ C+ C G
Sbjct: 404 QCAKGYYRPYGVPVDAPDGCIPCSCDPEHA---DGCEQGSGRCHCKPNFHGDNCEKCAIG 460
Query: 417 FTGLTY---------ANPQG-------CHRCDCNILGSRRDMPCDEESGRCLCLPNVVGP 460
+ + + P CDCN+ G ++ CD GRCLC P V GP
Sbjct: 461 YYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEI-CDAH-GRCLCRPGVEGP 518
Query: 461 KCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCP 520
+CD C + C+ C C S C+ TGQC CR G G C +C
Sbjct: 519 RCDTCRSGFYSFPI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCD-----RCL 570
Query: 521 DRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCN 573
Y + CD GT + G C C+ + GP C +C+ Y N
Sbjct: 571 SGAYDFPHCQGSSSACDPAGT----INSNLGYCQCKLHVEGPTCSRCKLLYWN 619
Score = 124 bits (311), Expect = 5e-28
Identities = 67/215 (31%), Positives = 97/215 (45%), Gaps = 27/215 (12%)
Query: 377 ISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNIL 436
+ CEC P GA G C P GQC C+ +V G +C C G G P C R
Sbjct: 1264 LPCECHPTGAT-GPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGR------ 1316
Query: 437 GSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLS---PQC 493
C+E +G+C C P V P+C+ C + + GCE C C ++ P+C
Sbjct: 1317 -----RLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPEC 1371
Query: 494 NQFTGQCPCREGFGGLMCS--AAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASG 551
++ +GQC C+ G C A+ + P+ C C+C+ GTE CD +G
Sbjct: 1372 DRDSGQCRCKPRITGRQCDRCASGFYRFPE---------CVPCNCNRDGTEPGVCDPGTG 1422
Query: 552 RCLCRPGLTGPRCDQCQRGYCNRYPVCV-ACHPCF 585
CLC+ + G C+ C+ G + P + C CF
Sbjct: 1423 ACLCKENVEGTECNVCREGSFHLDPANLKGCTSCF 1457
Score = 105 bits (263), Expect = 2e-22
Identities = 72/221 (32%), Positives = 90/221 (40%), Gaps = 42/221 (19%)
Query: 276 HDVCVCQHNTAGPNCERCAPFYNNRP-----WRPAEGQDAHEC---------------QR 315
H C+C+ GP C+ C + + P W A G C QR
Sbjct: 506 HGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQR 565
Query: 316 CD-----------CNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFR 364
CD C G S C DPA S Y C C+ H EG C RC+L Y+
Sbjct: 566 CDRCLSGAYDFPHCQGSSSAC--DPAGTINSNLGY---CQ-CKLHVEGPTCSRCKLLYWN 619
Query: 365 NRRPGASIQETCISCECDPDGAVPGA-PCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYA 423
+ S C C+C G V G C G C CK HV G+ CD C+ G+ L +
Sbjct: 620 LDKENPS---GCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKS 676
Query: 424 NPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQ 464
N GC C C+I G+ M C SG C C +VVG C +
Sbjct: 677 NYFGCQGCQCDIGGALSSM-CSGPSGVCQCREHVVGKVCQR 716
Score = 99.8 bits (247), Expect = 1e-20
Identities = 74/237 (31%), Positives = 95/237 (40%), Gaps = 40/237 (16%)
Query: 251 FCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDA 310
F H A C P + GP + + C CQ N G C RCA + P
Sbjct: 1258 FYHKGALPCECHPTGATGPHCSPEGGQ-CPCQPNVIGRQCTRCATGHYGFP--------- 1307
Query: 311 HECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGA 370
C+ C C C G C C T CE C+ H F + P A
Sbjct: 1308 -RCKPCSCG--RRLCE-----------EMTGQC-RCPPRTVRPQCEVCETHSF-SFHPMA 1351
Query: 371 SIQETCISCECDPDGAVPGA--PCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428
C C C G + A CD +GQC CK + G +CD C GF Y P+ C
Sbjct: 1352 G----CEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGF----YRFPE-C 1402
Query: 429 HRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQC--APYHWKLASGQGCEPCAC 483
C+CN G+ + CD +G CLC NV G +C+ C +H A+ +GC C C
Sbjct: 1403 VPCNCNRDGTEPGV-CDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
Score = 95.9 bits (237), Expect = 2e-19
Identities = 60/197 (30%), Positives = 87/197 (44%), Gaps = 34/197 (17%)
Query: 277 DVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQ 336
++C C AG +C+ C+P Y +R +G C C+CNGHS C
Sbjct: 1652 EICACPPAYAGDSCQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQDG-------- 1699
Query: 337 GAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCEC-DPDGAVPGAPCDPV 395
G+C NC+ +T G++CERCQ Y+ G ++ +C +C C + G +
Sbjct: 1700 ---SGICVNCQHNTAGEHCERCQEGYY-----GNAVHGSCRACPCPHTNSFATGCVVNGG 1751
Query: 396 TGQCVCKEHVQGERCDLCKPGFTGLTYANPQ----GCHRCDCNILGSRRDMPCDEESGRC 451
+C CK G +C+ C PG+ G NPQ C C CN G C +G C
Sbjct: 1752 DVRCSCKAGYTGTQCERCAPGYFG----NPQKFGGSCQPCSCNSNGQLGS--CHPLTGDC 1805
Query: 452 LCL-PNVVGP--KCDQC 465
+ P P +CD C
Sbjct: 1806 INQEPKDSSPAEECDDC 1822
Score = 84.3 bits (207), Expect = 6e-16
Identities = 150/716 (20%), Positives = 272/716 (37%), Gaps = 85/716 (11%)
Query: 451 CLCLPNVVGPKCDQCAPYHWK----LASGQGCEPCACDPHNSLSPQCNQFTGQCP-CREG 505
C C P G C C+P +++ L +G+ C PC C+ H++ QC +G C C+
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGR-CVPCNCNGHSN---QCQDGSGICVNCQHN 1709
Query: 506 FGGLMCSAAAIRQCPDRTYGDVATG-CRACDCDFRGTEGPGCDKASG--RCLCRPGLTGP 562
G C +C + YG+ G CRAC C + GC G RC C+ G TG
Sbjct: 1710 TAGEHCE-----RCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGT 1764
Query: 563 RCDQCQRGYC-NRYPVCVACHPCFQTYDADLREQALRFGRLRNATASLWSGPGLEDRGLA 621
+C++C GY N +C PC N+ L S L +
Sbjct: 1765 QCERCAPGYFGNPQKFGGSCQPC-----------------SCNSNGQLGSCHPLTGDCIN 1807
Query: 622 SRILDAKSKIEQIRAVLSSPAVTEQEVAQVASAILSLRRTLQGLQLDLPLEEETLSL--- 678
D+ S E+ S ++A + + ++ LQGL L E+ +
Sbjct: 1808 QEPKDS-SPAEECDDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQ 1866
Query: 679 PRDLESLDRSFNGLLTMYQRKREQFEKISSADPSGAFRMLSTAYEQSAQAAQ-------Q 731
+DL + ++ ++ + K E E+ D + F L + +++ AQ +
Sbjct: 1867 AKDLRNQLLNYRSAISNHGSKIEGLER-ELTDLNQEFETLQEKAQVNSRKAQTLNNNVNR 1925
Query: 732 VSDSSRLLD-QLRDSRREAERLVRQAGGGGGTGS--PKLVALRLEMSSLPDLTPTFNKLC 788
+ S++ LD ++++ R L++Q G G G+ P R + + N+
Sbjct: 1926 ATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRNF 1985
Query: 789 GNSRQMACTPISCPGELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQR 848
G + A E +++ G +A + + L + A+L
Sbjct: 1986 GKHLREA--------EADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSD 2037
Query: 849 TRQMIRAAEESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAAT 908
R ++ A A Q Q E + A + Q++E L +LT D+
Sbjct: 2038 LRARLQEAAAQAKQANGLNQENERALGAIQRQVKE----INSLQSDFTKYLTTADS---- 2089
Query: 909 IQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEE 968
+ + +AL L S E + +AA L LS ++++R+ + EE
Sbjct: 2090 --SLLQTNIALQLMEKS------QKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEE 2141
Query: 969 ARSRAHAVE---GQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPA 1025
A A +++ Q+E++ N G ++ A D L I+ + +
Sbjct: 2142 AEKHARSLQELAKQLEEIKRN-ASGDELVRCAVDAATAYENILNAIKAAEDAANRAASAS 2200
Query: 1026 EKLVTSMTKQ-----LGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALS-AQEGFE 1079
E + ++ K+ + ++L ++A+ + Q A +Q L+ E
Sbjct: 2201 ESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKE 2260
Query: 1080 RIKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLR 1135
I L+D L G+ A I S K+ + T E++D + ++ ++ R
Sbjct: 2261 VIDTNLTTLRDGL-HGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVER 2315
Score = 80.5 bits (197), Expect = 9e-15
Identities = 45/147 (30%), Positives = 61/147 (41%), Gaps = 41/147 (27%)
Query: 476 QGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIR------------------ 517
+G PC C P + P C+ GQCPC+ G C+ A
Sbjct: 1261 KGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCE 1320
Query: 518 ------QCPDRTYGDVA-------------TGCRACDCDFRGT---EGPGCDKASGRCLC 555
+CP RT GC C+C RGT P CD+ SG+C C
Sbjct: 1321 EMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRC 1380
Query: 556 RPGLTGPRCDQCQRGYCNRYPVCVACH 582
+P +TG +CD+C G+ R+P CV C+
Sbjct: 1381 KPRITGRQCDRCASGF-YRFPECVPCN 1406
Score = 72.4 bits (176), Expect = 2e-12
Identities = 54/170 (31%), Positives = 73/170 (42%), Gaps = 40/170 (23%)
Query: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
C C+GH+++C G +CV CQHNTAG +CERC Y G
Sbjct: 1687 CNCNGHSNQCQDGSG-------------ICVNCQHNTAGEHCERCQEGY--------YGN 1725
Query: 309 DAH-ECQRCDCNGHSETCHFDPAVFAASQGAYGG-VCDNCRDHTEGKNCERCQLHYFRNR 366
H C+ C C H+ + FA GG V +C+ G CERC YF N
Sbjct: 1726 AVHGSCRACPC-PHTNS-------FATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNP 1777
Query: 367 RPGASIQETCISCECDPDGAVPGAPCDPVTGQCV---CKEHVQGERCDLC 413
+ +C C C+ +G + C P+TG C+ K+ E CD C
Sbjct: 1778 Q---KFGGSCQPCSCNSNGQL--GSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 70.5 bits (171), Expect = 9e-12
Identities = 45/160 (28%), Positives = 68/160 (42%), Gaps = 15/160 (9%)
Query: 346 CRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCV-CKEH 404
C G +C+ C Y+R+ + C+ C C+ C +G CV C+ +
Sbjct: 1656 CPPAYAGDSCQGCSPGYYRDHK--GLYTGRCVPCNCNGHSN----QCQDGSGICVNCQHN 1709
Query: 405 VQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESG--RCLCLPNVVGPKC 462
GE C+ C+ G+ G A C C C S C G RC C G +C
Sbjct: 1710 TAGEHCERCQEGYYG--NAVHGSCRACPCPHTNSFAT-GCVVNGGDVRCSCKAGYTGTQC 1766
Query: 463 DQCAPYHW--KLASGQGCEPCACDPHNSLSPQCNQFTGQC 500
++CAP ++ G C+PC+C+ + L C+ TG C
Sbjct: 1767 ERCAPGYFGNPQKFGGSCQPCSCNSNGQLG-SCHPLTGDC 1805
Score = 42.0 bits (97), Expect = 0.003
Identities = 31/114 (27%), Positives = 45/114 (39%), Gaps = 22/114 (19%)
Query: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
C CH K G +G Q C C+ + G +C+ C Y E +
Sbjct: 631 CKCH--------KAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYF-----ALEKSN 677
Query: 310 AHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYF 363
CQ C C+ A+ + G GVC CR+H GK C+R + +Y+
Sbjct: 678 YFGCQGCQCD-------IGGALSSMCSGP-SGVCQ-CREHVVGKVCQRPENNYY 722
>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
Length = 3277
Score = 269 bits (688), Expect = 1e-71
Identities = 186/593 (31%), Positives = 262/593 (44%), Gaps = 97/593 (16%)
Query: 43 ASSTCG-------LTKPETYCTQYG-----------EWQMKCCKCDSRQPHNYYSHRVEN 84
A++TCG +PE YC G + Q C C+S P +H V N
Sbjct: 62 ATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQF-CDYCNSEDPRK--AHPVTN 118
Query: 85 VASSSGPMRWWQSQ-----NDVNPVSLQLDLDRRFQLQEVMMEF-QGPMPAGMLIERSSD 138
G RWWQS N V+L LDL + F + ++++F P P ++ERS D
Sbjct: 119 AID--GSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVD 176
Query: 139 FGKTWRVYQYLA---ADCTSTFPRVRQGRPQSWQDVRCQSLPQRPNARLNGGKVQLNLMD 195
FG T+ +QY A DC F R DV C + R NG V +
Sbjct: 177 FGSTYSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVV----VS 232
Query: 196 LVSGIPA----TQSQKIQEVGEITNLRVNFTR----LAPVPQRGYHPPSA----YYAVSQ 243
L++G P T S ++E + TN+R+ F R L + + P+ YY++
Sbjct: 233 LINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVTRRYYYSIKD 292
Query: 244 LRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWR 303
+ + G C C+GHA+ C P + C CQH+T G C+RC YN R WR
Sbjct: 293 ISIGGQCVCNGHAEVCNIN-----NPEKLFR----CECQHHTCGETCDRCCTGYNQRRWR 343
Query: 304 PAEGQDAHECQRCDCNGHSETCHFDPAV-----FAASQGAY--GGVCDNCRDHTEGKNCE 356
PA + +HEC+ C+C+GH+ C++DP V +QG Y GGVC NC+ +T G NCE
Sbjct: 344 PAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCE 403
Query: 357 RCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPG 416
+C Y+R + CI C CDP+ A C+ +G+C CK + G+ C+ C G
Sbjct: 404 QCAKGYYRPYGVPVDAPDGCIPCSCDPEHA---DGCEQGSGRCHCKPNFHGDNCEKCAIG 460
Query: 417 FTGLTY---------ANPQG-------CHRCDCNILGSRRDMPCDEESGRCLCLPNVVGP 460
+ + + P CDCN+ G ++ CD GRCLC P V GP
Sbjct: 461 YYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEI-CDAH-GRCLCRPGVEGP 518
Query: 461 KCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCP 520
+CD C + C+ C C S C+ TGQC CR G G C +C
Sbjct: 519 RCDTCRSGFYSFPI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCD-----RCL 570
Query: 521 DRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCN 573
Y + CD GT + G C C+ + GP C +C+ Y N
Sbjct: 571 SGAYDFPHCQGSSSACDPAGT----INSNLGYCQCKLHVEGPTCSRCKLLYWN 619
Score = 124 bits (311), Expect = 5e-28
Identities = 67/215 (31%), Positives = 97/215 (45%), Gaps = 27/215 (12%)
Query: 377 ISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNIL 436
+ CEC P GA G C P GQC C+ +V G +C C G G P C R
Sbjct: 1264 LPCECHPTGAT-GPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGR------ 1316
Query: 437 GSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLS---PQC 493
C+E +G+C C P V P+C+ C + + GCE C C ++ P+C
Sbjct: 1317 -----RLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPEC 1371
Query: 494 NQFTGQCPCREGFGGLMCS--AAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASG 551
++ +GQC C+ G C A+ + P+ C C+C+ GTE CD +G
Sbjct: 1372 DRDSGQCRCKPRITGRQCDRCASGFYRFPE---------CVPCNCNRDGTEPGVCDPGTG 1422
Query: 552 RCLCRPGLTGPRCDQCQRGYCNRYPVCV-ACHPCF 585
CLC+ + G C+ C+ G + P + C CF
Sbjct: 1423 ACLCKENVEGTECNVCREGSFHLDPANLKGCTSCF 1457
Score = 105 bits (263), Expect = 2e-22
Identities = 72/221 (32%), Positives = 90/221 (40%), Gaps = 42/221 (19%)
Query: 276 HDVCVCQHNTAGPNCERCAPFYNNRP-----WRPAEGQDAHEC---------------QR 315
H C+C+ GP C+ C + + P W A G C QR
Sbjct: 506 HGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSALGSYQMPCSSVTGQCECRPGVTGQR 565
Query: 316 CD-----------CNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFR 364
CD C G S C DPA S Y C C+ H EG C RC+L Y+
Sbjct: 566 CDRCLSGAYDFPHCQGSSSAC--DPAGTINSNLGY---CQ-CKLHVEGPTCSRCKLLYWN 619
Query: 365 NRRPGASIQETCISCECDPDGAVPGA-PCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYA 423
+ S C C+C G V G C G C CK HV G+ CD C+ G+ L +
Sbjct: 620 LDKENPS---GCSECKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKS 676
Query: 424 NPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQ 464
N GC C C+I G+ M C SG C C +VVG C +
Sbjct: 677 NYFGCQGCQCDIGGALSSM-CSGPSGVCQCREHVVGKVCQR 716
Score = 99.8 bits (247), Expect = 1e-20
Identities = 74/237 (31%), Positives = 95/237 (40%), Gaps = 40/237 (16%)
Query: 251 FCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDA 310
F H A C P + GP + + C CQ N G C RCA + P
Sbjct: 1258 FYHKGALPCECHPTGATGPHCSPEGGQ-CPCQPNVIGRQCTRCATGHYGFP--------- 1307
Query: 311 HECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGA 370
C+ C C C G C C T CE C+ H F + P A
Sbjct: 1308 -RCKPCSCG--RRLCE-----------EMTGQC-RCPPRTVRPQCEVCETHSF-SFHPMA 1351
Query: 371 SIQETCISCECDPDGAVPGA--PCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC 428
C C C G + A CD +GQC CK + G +CD C GF Y P+ C
Sbjct: 1352 G----CEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGF----YRFPE-C 1402
Query: 429 HRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQC--APYHWKLASGQGCEPCAC 483
C+CN G+ + CD +G CLC NV G +C+ C +H A+ +GC C C
Sbjct: 1403 VPCNCNRDGTEPGV-CDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
Score = 95.9 bits (237), Expect = 2e-19
Identities = 60/197 (30%), Positives = 87/197 (44%), Gaps = 34/197 (17%)
Query: 277 DVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQ 336
++C C AG +C+ C+P Y +R +G C C+CNGHS C
Sbjct: 1652 EICACPPAYAGDSCQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQDG-------- 1699
Query: 337 GAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCEC-DPDGAVPGAPCDPV 395
G+C NC+ +T G++CERCQ Y+ G ++ +C +C C + G +
Sbjct: 1700 ---SGICVNCQHNTAGEHCERCQEGYY-----GNAVHGSCRACPCPHTNSFATGCVVNGG 1751
Query: 396 TGQCVCKEHVQGERCDLCKPGFTGLTYANPQ----GCHRCDCNILGSRRDMPCDEESGRC 451
+C CK G +C+ C PG+ G NPQ C C CN G C +G C
Sbjct: 1752 DVRCSCKAGYTGTQCERCAPGYFG----NPQKFGGSCQPCSCNSNGQLGS--CHPLTGDC 1805
Query: 452 LCL-PNVVGP--KCDQC 465
+ P P +CD C
Sbjct: 1806 INQEPKDSSPAEECDDC 1822
Score = 86.3 bits (212), Expect = 2e-16
Identities = 147/693 (21%), Positives = 256/693 (36%), Gaps = 137/693 (19%)
Query: 451 CLCLPNVVGPKCDQCAPYHWK----LASGQGCEPCACDPHNSLSPQCNQFTGQCP-CREG 505
C C P G C C+P +++ L +G+ C PC C+ H++ QC +G C C+
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYRDHKGLYTGR-CVPCNCNGHSN---QCQDGSGICVNCQHN 1709
Query: 506 FGGLMCSAAAIRQCPDRTYGDVATG-CRACDCDFRGTEGPGCDKASG--RCLCRPGLTGP 562
G C +C + YG+ G CRAC C + GC G RC C+ G TG
Sbjct: 1710 TAGEHCE-----RCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGT 1764
Query: 563 RCDQCQRGY---------------CNRYPVCVACHP------------------------ 583
+C++C GY CN +CHP
Sbjct: 1765 QCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 1824
Query: 584 CFQTYDADLREQALRFGRLRNATASLWSGPGL--EDRGLASRILDAKSKIEQIRAVLSSP 641
C T DL + +++ L + GL + R + ++ D ++++ R+ +S+
Sbjct: 1825 CVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNH 1884
Query: 642 AVTEQEVAQVASAILSLRRTLQGLQLDL-PLEEETLSLPRDLESLDRSFNGLLTMYQRKR 700
S I L R L L + L+E+ R ++L+ + N Q +
Sbjct: 1885 ----------GSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVN---RATQSAK 1931
Query: 701 EQFEKISSADPSGAFRMLSTAYEQSAQA-----AQQVSDS----SRLLDQLRDSRREAER 751
E KI + + ++++ Q A + DS L LR +EA
Sbjct: 1932 ELDVKIKNVIRNVHMLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAA 1991
Query: 752 LVRQAGGGGGTGSPKLVALRLEMSSLPDLTPTFNK-LCGNSRQMACTPISCP-------- 802
+QA G L A++ ++ + L F K L + T I+
Sbjct: 1992 QAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKE 2051
Query: 803 -GELCPQDNGT--ACGSRCRGVLPRAGGAFLM--AGQVAEQLRGFNAQLQRTR------Q 851
+L N + R + AG L+ A + A L+ QL+ + +
Sbjct: 2052 YEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDE 2111
Query: 852 MIRAAEESA-------SQIQSSAQRLETQVSASRSQME----EDVRRTRLLIQQVRDFLT 900
++R A ++A + I+++ SAS S ++ ED+ R + D L
Sbjct: 2112 LVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLL 2171
Query: 901 DPD--TDAATIQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIAR 958
+ T QEVS A+ L + TV +++ +D L+ + +
Sbjct: 2172 NEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEV------------IDTNLTTLRDGLHG 2219
Query: 959 ARR--LQAEAEEARSRAHAVEGQVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVA 1016
+R + A A+S ++V+ L ++ +DT T
Sbjct: 2220 IQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNE--------- 2270
Query: 1017 EVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQ 1049
+ ++ L A+ V +T +L D W ++E + Q
Sbjct: 2271 DFKKALTDADNSVNKLTNKLPDLWRKIESINQQ 2303
Score = 80.5 bits (197), Expect = 9e-15
Identities = 45/147 (30%), Positives = 61/147 (41%), Gaps = 41/147 (27%)
Query: 476 QGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIR------------------ 517
+G PC C P + P C+ GQCPC+ G C+ A
Sbjct: 1261 KGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCE 1320
Query: 518 ------QCPDRTYGDVA-------------TGCRACDCDFRGT---EGPGCDKASGRCLC 555
+CP RT GC C+C RGT P CD+ SG+C C
Sbjct: 1321 EMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRC 1380
Query: 556 RPGLTGPRCDQCQRGYCNRYPVCVACH 582
+P +TG +CD+C G+ R+P CV C+
Sbjct: 1381 KPRITGRQCDRCASGF-YRFPECVPCN 1406
Score = 72.4 bits (176), Expect = 2e-12
Identities = 54/170 (31%), Positives = 73/170 (42%), Gaps = 40/170 (23%)
Query: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
C C+GH+++C G +CV CQHNTAG +CERC Y G
Sbjct: 1687 CNCNGHSNQCQDGSG-------------ICVNCQHNTAGEHCERCQEGY--------YGN 1725
Query: 309 DAH-ECQRCDCNGHSETCHFDPAVFAASQGAYGG-VCDNCRDHTEGKNCERCQLHYFRNR 366
H C+ C C H+ + FA GG V +C+ G CERC YF N
Sbjct: 1726 AVHGSCRACPC-PHTNS-------FATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNP 1777
Query: 367 RPGASIQETCISCECDPDGAVPGAPCDPVTGQCV---CKEHVQGERCDLC 413
+ +C C C+ +G + C P+TG C+ K+ E CD C
Sbjct: 1778 Q---KFGGSCQPCSCNSNGQL--GSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 42.0 bits (97), Expect = 0.003
Identities = 31/114 (27%), Positives = 45/114 (39%), Gaps = 22/114 (19%)
Query: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
C CH K G +G Q C C+ + G +C+ C Y E +
Sbjct: 631 CKCH--------KAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYF-----ALEKSN 677
Query: 310 AHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYF 363
CQ C C+ A+ + G GVC CR+H GK C+R + +Y+
Sbjct: 678 YFGCQGCQCD-------IGGALSSMCSGP-SGVCQ-CREHVVGKVCQRPENNYY 722
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 253 bits (647), Expect = 6e-67
Identities = 169/504 (33%), Positives = 233/504 (46%), Gaps = 59/504 (11%)
Query: 20 ACSRGA-----CYPPVGDLLVGRTRFLRASSTCGLTKPETYCTQYGEWQM--KCCKCDSR 72
AC GA C P + GR +AS TCG + PE +C G C +CD+
Sbjct: 24 ACYDGAGRPQRCLPVFENAAFGR--LAQASHTCG-SPPEDFCPHVGAAGAGAHCQRCDAA 80
Query: 73 QPHNYYSHRVENVASSSGPMRWWQSQNDV------NPVSLQLDLDRRFQLQEVMMEFQGP 126
P +++ S WWQS + V++ L L + +++ V ++F
Sbjct: 81 DPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLRLGKAYEITYVRLKFHTS 140
Query: 127 MPAGMLIERSSDFGKTWRVYQYLAADCTSTF--PRVRQGRPQSWQDVRCQSLPQRPNARL 184
P I + S W YQ+ +A C T+ P + RP + V + + L
Sbjct: 141 RPESFAIYKRSRADGPWEPYQFYSASCQKTYGRPEGQYLRPGEDERVAFCTSEFSDISPL 200
Query: 185 NGGKVQLNLMDLVSGIPAT----QSQKIQEVGEITNLRVNFTRLAPVPQRGYHPP----S 236
+GG V + ++ G P+ +S +QE T L ++ RL + P S
Sbjct: 201 SGGNVAFSTLE---GRPSAYNFEESPGLQEWVTSTELLISLDRLNTFGDDIFKDPKVLQS 257
Query: 237 AYYAVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPF 296
YYAVS + G C C+GHA C GP A Q+ C CQHNT G +CERC PF
Sbjct: 258 YYYAVSDFSVGGRCKCNGHASEC--------GPDVAGQL--ACRCQHNTTGTDCERCLPF 307
Query: 297 YNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCE 356
+ +RPW + AHEC C+C+G SE C FD +F ++ +GG C +CRDHT G +CE
Sbjct: 308 FQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRST--GHGGRCHHCRDHTAGPHCE 365
Query: 357 RCQLHYFR--NRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCK 414
RCQ +++ R P C C+C G++ CD TG C CK V G +CD C
Sbjct: 366 RCQENFYHWDPRMP-------CQPCDCQSAGSL-HLQCDD-TGTCACKPTVTGWKCDRCL 416
Query: 415 PGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLA- 473
PGF L+ GC C CN GS CD SGRC C NV G CD+C P + L
Sbjct: 417 PGFHSLSEG---GCRPCTCNPAGSLD--TCDPRSGRCPCKENVEGNLCDRCRPGTFNLQP 471
Query: 474 -SGQGCEPCACDPHNSLSPQCNQF 496
+ GC C C H+ + QF
Sbjct: 472 HNPAGCSSCFCYGHSKVCASTAQF 495
Score = 197 bits (502), Expect = 4e-50
Identities = 120/348 (34%), Positives = 156/348 (44%), Gaps = 53/348 (15%)
Query: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAP-FYNNRPWRPAEGQ 308
C C+ H C P G +CVC H+T GP+CERC P FY N P GQ
Sbjct: 707 CTCNQHGT-CDPNTG-------------ICVCSHHTEGPSCERCLPGFYGN----PFAGQ 748
Query: 309 DAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRP 368
A +CQ C C G S C P VC +C G+ CE C +F +
Sbjct: 749 -ADDCQPCPCPGQS-ACTTIPESREV-------VCTHCPPGQRGRRCEVCDDGFFGDPLG 799
Query: 369 GASIQETCISCEC----DPDGAVPGAPCDPVTGQCV-CKEHVQGERCDLCKPGFTGLTYA 423
+ C C+C DP+ CDP++G C+ C + G+ C+ C+ GF G A
Sbjct: 800 LFGHPQPCHQCQCSGNVDPNAV---GNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALA 856
Query: 424 NPQG--CHRCDCNILGS-RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEP 480
C C C+ GS MPCD +G+C CLP+V C +C P + L G+GC
Sbjct: 857 PRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRS 916
Query: 481 CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRG 540
C C P S QC+ TGQC CR G G C +C +G GCRAC C G
Sbjct: 917 CKCHPLGSQEDQCHPKTGQCTCRPGVTGQACD-----RCQLGFFGFSIKGCRACRCSPLG 971
Query: 541 TEGPGCDKASGRCLCRPGLTGPRCDQCQRGY--------CNRYPVCVA 580
C + +G C+CRPG G +CD+C + C + P C A
Sbjct: 972 AASAQCHE-NGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSCYA 1018
Score = 125 bits (313), Expect = 3e-28
Identities = 95/333 (28%), Positives = 118/333 (35%), Gaps = 97/333 (29%)
Query: 345 NCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEH 404
+C G+ CE C Y R G +C+ C C+ G CDP TG CVC H
Sbjct: 674 SCPTGYTGQFCESCAPGYKREMPQGGPYA-SCVPCTCNQHGT-----CDPNTGICVCSHH 727
Query: 405 VQGERCDLCKPGFTGLTYAN------------------------------PQG-----CH 429
+G C+ C PGF G +A P G C
Sbjct: 728 TEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCE 787
Query: 430 RCDCNILGS-----RRDMPC-----------------DEESGRCL-CLPNVVGPKCDQCA 466
CD G PC D SG CL CL N G C+ C
Sbjct: 788 VCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQ 847
Query: 467 PYHWKLA----SGQGCEPCACDPHNSLSPQ--CNQFTGQCPCREGFGGLMCSAAAIRQCP 520
+ A C PC+C P S+S Q C+ TGQC C CS R P
Sbjct: 848 EGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCS----RCYP 903
Query: 521 DRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY--------- 571
GCR+C C G++ C +G+C CRPG+TG CD+CQ G+
Sbjct: 904 GFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCR 963
Query: 572 -------------CNRYPVCVACHPCFQTYDAD 591
C+ CV C P F+ Y D
Sbjct: 964 ACRCSPLGAASAQCHENGTCV-CRPGFEGYKCD 995
Score = 101 bits (251), Expect = 5e-21
Identities = 72/222 (32%), Positives = 92/222 (41%), Gaps = 35/222 (15%)
Query: 380 ECDPDGAVPGAPCDPVTGQ--CVCKEHVQGERCDLCKPGFTGLTYAN--PQGCHRC-DCN 434
EC PD V GQ C C+ + G C+ C P F +A + H C CN
Sbjct: 279 ECGPD----------VAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCN 328
Query: 435 ILGSRRDMPCDEE-------SGRCL-CLPNVVGPKCDQCAP--YHWKLASGQGCEPCACD 484
G + D E GRC C + GP C++C YHW C+PC C
Sbjct: 329 CSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWD--PRMPCQPCDCQ 386
Query: 485 PHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGP 544
SL QC+ TG C C+ G C +C + GCR C C+ G+
Sbjct: 387 SAGSLHLQCDD-TGTCACKPTVTGWKCD-----RCLPGFHSLSEGGCRPCTCNPAGSLDT 440
Query: 545 GCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVA-CHPCF 585
CD SGRC C+ + G CD+C+ G N P A C CF
Sbjct: 441 -CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCF 481
Score = 47.8 bits (112), Expect = 6e-05
Identities = 26/87 (29%), Positives = 35/87 (40%), Gaps = 6/87 (6%)
Query: 500 CPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGL 559
C C G+ G C + A + G C C C+ GT CD +G C+C
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHT 728
Query: 560 TGPRCDQCQRGYCNRYPVCVA--CHPC 584
GP C++C G+ A C PC
Sbjct: 729 EGPSCERCLPGFYGNPFAGQADDCQPC 755
Score = 32.0 bits (71), Expect = 3.5
Identities = 73/361 (20%), Positives = 139/361 (38%), Gaps = 52/361 (14%)
Query: 821 VLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVS---AS 877
+LP A AFL EQ+ ++ R+ ++ + A Q+ +Q+ TQ++ A
Sbjct: 1068 LLPGAREAFL------EQMMSLEGAVKAAREQLQRLNKGARCAQAGSQKTCTQLADLEAV 1121
Query: 878 RSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLALWLPTDSAT--------VL 929
EE++ ++ + P +EA D+AT L
Sbjct: 1122 LESSEEEILHAAAILASLEIPQEGPSQPTKWSHLATEARALARSHRDTATKIAATAWRAL 1181
Query: 930 QKMNEIQAIAARLPNVDLVLSQTKQDIA-RARRLQAEAEEARSRAHAVEGQVEDVVGNLR 988
N A+ L + L +T++D+ R + +QA + R+ V + E V+ ++
Sbjct: 1182 LASNTSYALLWNLLEGRVAL-ETQRDLEDRYQEVQAAQKALRTAVAEVLPEAESVLATVQ 1240
Query: 989 Q------GTVALQEAQDTMQGTSRS------LRLIQDRVAEVQQVLRPAEKLV---TSMT 1033
Q +AL + + SR+ + ++ VA Q + A + + T
Sbjct: 1241 QVGADTAPYLALLASPGALPQKSRAEDLGLKAKALEKTVASWQHMATEAARTLQTAAQAT 1300
Query: 1034 KQLGDFWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYAELKDRLG 1093
+ + T++ + A Q + +VQA + + L+ EG +K ++ KD
Sbjct: 1301 LRQTEPLTKLHQEARAALTQASSSVQAATVTVMGARTLLADLEG---MKLQFPRPKD--- 1354
Query: 1094 QSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKR 1153
Q A + + ++ L +T R K + E + G+ A + SA G E
Sbjct: 1355 -------QAALQRKADSVSDRLLADT-----RKKTKQAERMLGNAAPLSSSAKKKGREAE 1402
Query: 1154 V 1154
V
Sbjct: 1403 V 1403
>gi|148613884 netrin 1 [Homo sapiens]
Length = 604
Score = 223 bits (569), Expect = 6e-58
Identities = 134/411 (32%), Positives = 210/411 (51%), Gaps = 39/411 (9%)
Query: 26 CYPPVGDLLVGRTRFLRASSTCGLTKPETYC--TQYGEWQMKCCK-CDSRQPHNYYSHRV 82
C P + G+ +R SSTCG P YC ++ GE +++ C C++ P +
Sbjct: 51 CIPDFVNAAFGKD--VRVSSTCG-RPPARYCVVSERGEERLRSCHLCNASDPKKAHPPAF 107
Query: 83 ENVASSSGPMRWWQSQNDV---NPVSLQLDLDRRFQLQEVMMEFQGPMPAGMLIERSSDF 139
++ + WQS+N + + V+L L L ++F++ V ++F P P M I +S D+
Sbjct: 108 LTDLNNPHNLTCWQSENYLQFPHNVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDY 167
Query: 140 GKTWRVYQYLAADCTSTFPRVRQG--RPQSWQDVRCQS--LPQRPNARLNGGKVQLNLMD 195
G+TW +Q+ + C + R + Q+ Q+ C RP L+GG + + +D
Sbjct: 168 GRTWVPFQFYSTQCRKMYNRPHRAPITKQNEQEAVCTDSHTDMRP---LSGGLIAFSTLD 224
Query: 196 LVSGIPATQ----SQKIQEVGEITNLRVNFTRLAPVPQRGYHPP-----SAYYAVSQLRL 246
G P+ S +Q+ T++RV F+RL S +YAVS L++
Sbjct: 225 ---GRPSAHDFDNSPVLQDWVTATDIRVAFSRLHTFGDENEDDSELARDSYFYAVSDLQV 281
Query: 247 QGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAE 306
G C C+GHA RC S VC C+HNTAGP C+RC PF+ +RPW+ A
Sbjct: 282 GGRCKCNGHAARCVRDRDDSL----------VCDCRHNTAGPECDRCKPFHYDRPWQRAT 331
Query: 307 GQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNR 366
++A+EC C+CN H+ C F+ ++ S GGVC NCR +T G++C C+ Y+R+
Sbjct: 332 AREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDM 391
Query: 367 RPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGF 417
+ ++ C +C+C P GA G C+ TGQC CK+ V G C+ C G+
Sbjct: 392 GKPITHRKACKACDCHPVGAA-GKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
Score = 79.7 bits (195), Expect = 1e-14
Identities = 54/182 (29%), Positives = 81/182 (44%), Gaps = 37/182 (20%)
Query: 430 RCDCNILGSR--RDMPCDEESGRCLCLPNVVGPKCDQCAPYH----WKLASGQGCEPCAC 483
RC CN +R RD ++S C C N GP+CD+C P+H W+ A+ + C
Sbjct: 284 RCKCNGHAARCVRDR---DDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVA 340
Query: 484 DPHNSLSPQCN-----------QFTGQC-PCREGFGGLMCSAAAIRQCPDRTYGDVAT-- 529
N + +C + G C CR G C C + Y D+
Sbjct: 341 CNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHC-----HYCKEGYYRDMGKPI 395
Query: 530 ----GCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY-CNRYPVCVACHPC 584
C+ACDC G G C++ +G+C C+ G+TG C++C +GY +R P+ PC
Sbjct: 396 THRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGYQQSRSPIA----PC 451
Query: 585 FQ 586
+
Sbjct: 452 IK 453
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 213 bits (541), Expect = 1e-54
Identities = 153/528 (28%), Positives = 229/528 (43%), Gaps = 90/528 (17%)
Query: 14 LLHAQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYCTQYGEW------QMKCC 67
LL C + +P + L + + ++TCG PE +C +C
Sbjct: 10 LLCVAAQCRQRGLFPAI--LNLASNAHISTNATCGEKGPEMFCKLVEHVPGRPVRNPQCR 67
Query: 68 KCDSRQPHNYYSHRVENVASSSGPMRWWQSQNDVNP-----VSLQLDLDRRFQLQEVMME 122
CD + H + + G WWQS + N V++ LDL + FQ+ V+++
Sbjct: 68 ICDGNSANPRERHPISHAID--GTNNWWQSPSIQNGREYHWVTITLDLRQVFQVAYVIIK 125
Query: 123 F-QGPMPAGMLIERSSDFGKTWRVYQYLA---ADCTSTFPRVRQGRPQSWQ---DVRCQS 175
P P ++ERS D G T+ +QY A ++C S + + P +++ +V C S
Sbjct: 126 AANAPRPGNWILERSLD-GTTFSPWQYYAVSDSECLSRYNITPRRGPPTYRADDEVICTS 184
Query: 176 LPQRPNARLNGGKVQLNLMDLVSGIPATQ--SQKIQEVGEITNLRVNFTR---------- 223
R L G++ +L ++G P+ S K+ E +R+ R
Sbjct: 185 YYSRL-VPLEHGEIHTSL---INGRPSADDLSPKLLEFTSARYIRLRLQRIRTLNADLMT 240
Query: 224 --------LAPVPQRGYHPPSAYYAVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQV 275
L P+ R Y YY++ + + G C C+GHA C P
Sbjct: 241 LSHREPKELDPIVTRRY-----YYSIKDISVGGMCICYGHASSC---------PWDETTK 286
Query: 276 HDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVF--- 332
C C+HNT G +C RC P Y+ +PWRP + C+ C+C+ ++ C++D +V
Sbjct: 287 KLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQK 346
Query: 333 ----AASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVP 388
A Q GGVC NC +T G NCE C Y+R + E C C CDP G++
Sbjct: 347 KSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSL- 405
Query: 389 GAPC-----------DPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILG 437
+ C GQC CKE GE+CD C+ G Y + C C CN +G
Sbjct: 406 SSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLG-----YKDYPTCVSCGCNPVG 460
Query: 438 SRRDMPCDEESGRCLCLPNVVGPKCDQCAP--YHWKLASGQGCEPCAC 483
S D PC +G C+C NV G CD+C P Y+ K + +GC C C
Sbjct: 461 SASDEPC---TGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFC 505
Score = 204 bits (518), Expect = 5e-52
Identities = 137/415 (33%), Positives = 170/415 (40%), Gaps = 101/415 (24%)
Query: 236 SAYYAVSQLRLQG---SCFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCE 291
S YY V + G C CHGHA C VH VC+ C HNT G +CE
Sbjct: 725 SGYYRVDGILFGGICQPCECHGHAAEC--------------NVHGVCIACAHNTTGVHCE 770
Query: 292 RCAPFYNNRPWRPAEGQDAHECQRCDC------NGHSETCHFDPAVFAASQGAYGGVCDN 345
+C P + P R G +CQ C C N S TCH + VCD
Sbjct: 771 QCLPGFYGEPSRGTPG----DCQPCACPLTIASNNFSPTCHLNDGDEV--------VCDW 818
Query: 346 CRDHTEGKNCERCQLHYFRNRR-PGASIQETCISCEC----DPDGAVPGAPCDPVTGQCV 400
C G CERC Y+ N PG E+C+ C+C DP A CD VTG+C+
Sbjct: 819 CAPGYSGAWCERCADGYYGNPTVPG----ESCVPCDCSGNVDPSEA---GHCDSVTGECL 871
Query: 401 -CKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVG 459
C + G C+ C GF G + C C+C++ GS + C E+G C C PNV G
Sbjct: 872 KCLGNTDGAHCERCADGFYG-DAVTAKNCRACECHVKGSHSAV-CHLETGLCDCKPNVTG 929
Query: 460 PKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAA---- 515
+CDQC ++ L SG GC PC C S+S C GQC C G G C A
Sbjct: 930 QQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTD-EGQCHCVPGVAGKRCDRCAHGFY 988
Query: 516 ------------------------------------IRQCPDRTYG-DVATGCRACDCDF 538
+C D +G D GC+AC+C
Sbjct: 989 AYQDGSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCSL 1048
Query: 539 RGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDADLR 593
G+ CD +G C C+ G CDQC GY +P CV C D DLR
Sbjct: 1049 VGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGY-RDFPDCVPC-------DCDLR 1095
Score = 101 bits (251), Expect = 5e-21
Identities = 178/803 (22%), Positives = 301/803 (37%), Gaps = 144/803 (17%)
Query: 399 CVCKEHVQGERCDLCKPGFTG--LTYANPQG-------CHRCDCNILGSRRDMPCDEESG 449
CVC G C C PG+ L + +G C C CN CD +G
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCN----NHSDTCDPNTG 1417
Query: 450 RCL-CLPNVVGPKCDQCAP-YHWKLA-SGQGCEPCACDPHN---SLSPQC---NQFTGQC 500
+CL C N G CD C Y+ K+ S C CAC PH+ S SP C +C
Sbjct: 1418 KCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCAC-PHSPPASFSPTCVLEGDHDFRC 1476
Query: 501 P-CREGFGGLMCSAAAIRQCPDRTYGDVAT---GCRACDCDFRGTEGPGCDKASGRCLCR 556
C G+ G C +C YG+ T C+ CDC+ G+ CD+ SG+C+CR
Sbjct: 1477 DACLLGYEGKHCE-----RCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCR 1531
Query: 557 PGLTGPRCDQCQRGYCNRYPVCVAC-HPCFQTYDADLREQA-------------LRFG-- 600
G +G RCD+C+ + CV+C C DL E + +G
Sbjct: 1532 LGASGLRCDECEPRHILMETDCVSCDDECVGVLLNDLDEIGDAVLSLNLTGIIPVPYGIL 1591
Query: 601 -RLRNATASLWSGPGLED----------RGLASRILDAKSKIEQIRAVLSS-PAVTE--- 645
L N T L E+ G+A + + K+ ++ A TE
Sbjct: 1592 SNLENTTKYLQESLLKENMQKDLGKIKLEGVAEETDNLQKKLTRMLASTQKVNRATERIF 1651
Query: 646 QEVAQVASAI----LSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTMYQ-RKR 700
+E +A AI +S+ ++ L+ L+E+ L L+++ ++ LL + Q R
Sbjct: 1652 KESQDLAIAIERLQMSITEIMEKTTLNQTLDEDFLLPNSTLQNMQQNGTSLLEIMQIRDF 1711
Query: 701 EQFEKISSADPSGAFRMLSTAYEQSAQAAQQV----SDSSRLLDQLRDSRREAERLVRQA 756
Q + ++ + A +LS E + +++ +S +L + + + AE LVR+A
Sbjct: 1712 TQLHQNATLELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNELKAAEALVREA 1771
Query: 757 GGGGGTGSPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGELCPQDNGTACGS 816
+ L+ + + D KL Q + + G
Sbjct: 1772 EAKMQESNHLLLMVNANLREFSD-----KKLHVQEEQNLTSELIVQG------------- 1813
Query: 817 RCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQMIRAAEESASQIQSSAQRLETQVSA 876
RG++ A E L +L IR + S ++ A
Sbjct: 1814 --RGLIDAAAAQTDAVQDALEHLEDHQDKLLLWSAKIRHHIDDLVMHMSQRNAVDLVYRA 1871
Query: 877 SRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVS-EAVLALWLPTDSATVLQKMNEI 935
E Q++ D L + I+ VS A A ++ + +++++ E+
Sbjct: 1872 EDHAAE---------FQRLADVLY---SGLENIRNVSLNATSAAYVHYNIQSLIEESEEL 1919
Query: 936 QAIAARLPNVDLVLSQT-----KQDIARARRLQAEAEEARSRAHAVEGQVEDVVGNLRQG 990
A R +LS++ K + R+ R E + + ++ + LR
Sbjct: 1920 ARDAHRTVTETSLLSESLVSNGKAAVQRSSRFLKEGNNLSRKLPGIALELSE----LRNK 1975
Query: 991 TVALQE-AQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELRHQ 1049
T QE A + + T+ SL +++ ++ K + D + +EL
Sbjct: 1976 TNRFQENAVEITRQTNESLLILR------------------AIPKGIRDKGAKTKELATS 2017
Query: 1050 ARQQGAEAVQAQQLAEGASEQALSAQEGFERIKQKYAELKDRLGQSSMLG-EQGARIQSV 1108
A Q AV + G S++ L+ R+ E L S+M G +++ V
Sbjct: 2018 ASQ---SAVSTLRDVAGLSQELLNTSASLSRVNTTLRETHQLLQDSTMATLLAGRKVKDV 2074
Query: 1109 KTEAEELFGETMEMMDRMKDMEL 1131
+ +A LF DR+K +++
Sbjct: 2075 EIQANLLF-------DRLKPLKM 2090
Score = 98.6 bits (244), Expect = 3e-20
Identities = 59/167 (35%), Positives = 76/167 (45%), Gaps = 26/167 (15%)
Query: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
C C+ H+D C P G C NTAG +C+ C Y + A
Sbjct: 1403 CSCNNHSDTCDPNTGKCLN------------CGDNTAGDHCDVCTSGYYGKVTGSAS--- 1447
Query: 310 AHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRN-RRP 368
+C C C HS F P +G + CD C EGK+CERC Y+ N + P
Sbjct: 1448 --DCALCACP-HSPPASFSPT--CVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTP 1502
Query: 369 GASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKP 415
G S C C+C+P G+V G CD +GQCVC+ G RCD C+P
Sbjct: 1503 GGS----CQKCDCNPHGSVHG-DCDRTSGQCVCRLGASGLRCDECEP 1544
Score = 94.4 bits (233), Expect = 6e-19
Identities = 69/248 (27%), Positives = 101/248 (40%), Gaps = 51/248 (20%)
Query: 366 RRPGASIQETCISCECDPDGAVPGAPCDPVTG--QCVCKEHVQGERCDLCKPGFTGL--- 420
RR SI++ + C G P D T QC C+ + GE C+ C PG+
Sbjct: 255 RRYYYSIKDISVGGMCICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWR 314
Query: 421 --TYANPQGCHRCDCNILGSRRDMPCDEE----------------SGRCL-CLPNVVGPK 461
T ++ C C+C+ +D DE G C+ CL N +G
Sbjct: 315 PGTVSSGNTCEACNCH--NKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGIN 372
Query: 462 CDQCA-----PYHWKLASGQGCEPCACDPHNSLSPQC-----------NQFTGQCPCREG 505
C+ C P+ + C PC CDP SLS C + GQCPC+EG
Sbjct: 373 CETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEG 432
Query: 506 FGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCD 565
+ G C + Y D T C +C C+ G+ + +G C+C+ + G CD
Sbjct: 433 YTGEKCDRCQLG------YKDYPT-CVSCGCNPVGSASD--EPCTGPCVCKENVEGKACD 483
Query: 566 QCQRGYCN 573
+C+ G+ N
Sbjct: 484 RCKPGFYN 491
Score = 73.9 bits (180), Expect = 8e-13
Identities = 56/194 (28%), Positives = 73/194 (37%), Gaps = 47/194 (24%)
Query: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
C C + C P+ G CVC +T G CE C + W G D
Sbjct: 998 CDCPHTQNTCDPETGE-------------CVCPPHTQGVKCEECEDGH----W----GYD 1036
Query: 310 AHE-CQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRP 368
A CQ C+C+ T H V Q C+ G+ C++C L Y
Sbjct: 1037 AEVGCQACNCSLVGSTHHRCDVVTGHCQ---------CKSKFGGRACDQCSLGY------ 1081
Query: 369 GASIQETCISCECDPDGAVPGA--------PCDPVTGQCVCKEHVQGERCDLCKPGFTGL 420
C+ C+CD G A C TG C CKE+V G +C+ C+ G L
Sbjct: 1082 --RDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFAL 1139
Query: 421 TYANPQGCHRCDCN 434
NP GC C C+
Sbjct: 1140 RADNPLGCSPCFCS 1153
Score = 71.2 bits (173), Expect = 5e-12
Identities = 59/193 (30%), Positives = 77/193 (39%), Gaps = 52/193 (26%)
Query: 433 CNILGSRRDMPCDEESGR--CLCLPNVVGPKCDQCAP-YH---WK---LASGQGCEPCAC 483
C G P DE + + C C N G C++C P YH W+ ++SG CE C C
Sbjct: 270 CICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNC 329
Query: 484 DPHN---------SLSPQ------CNQFTGQ---CPCREGFGGLMCSAAAIRQCPDRTYG 525
HN S++ Q QF G C + G+ C C D Y
Sbjct: 330 --HNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCET-----CIDGYYR 382
Query: 526 DVATG------CRACDCDFRGTEGPGC-----------DKASGRCLCRPGLTGPRCDQCQ 568
CR C+CD G+ C K G+C C+ G TG +CD+CQ
Sbjct: 383 PHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQ 442
Query: 569 RGYCNRYPVCVAC 581
GY YP CV+C
Sbjct: 443 LGY-KDYPTCVSC 454
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 200 bits (509), Expect = 6e-51
Identities = 145/521 (27%), Positives = 225/521 (43%), Gaps = 88/521 (16%)
Query: 19 QACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYCTQYGEW--------QMKCCKCD 70
QA + +P V L + + ++TCG PE YC Q + C +
Sbjct: 32 QAHQQRGLFPAV--LNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRICNQN 89
Query: 71 SRQPHNYYSHRVENVASSSGPMRWWQSQNDVNP-----VSLQLDLDRRFQLQEVMMEF-Q 124
S P+ H + N G WWQS + N V++ LDL + FQ+ V+++
Sbjct: 90 SSNPNQ--RHPITNAID--GKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAAN 145
Query: 125 GPMPAGMLIERSSDFG--KTWRVYQYLAADCTSTFPRVRQGRPQSW---QDVRCQSLPQR 179
P P ++ERS D K W+ + +C + + + P S+ +V C S +
Sbjct: 146 SPRPGNWILERSLDDVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSK 205
Query: 180 PNARLNGGKVQLNLMDLVSGIPATQ--SQKIQEVGEITNLRVNFTRLA------------ 225
+ L G++ ++L ++G P+ S ++ E +R+ F R+
Sbjct: 206 IHP-LENGEIHISL---INGRPSADDPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHK 261
Query: 226 ------PVPQRGYHPPSAYYAVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVC 279
P+ R Y YY+V + + G C C+GHA C P + C
Sbjct: 262 DPREIDPIVTRRY-----YYSVKDISVGGMCICYGHARACPLDPATNKSR---------C 307
Query: 280 VCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAAS---- 335
C+HNT G +C++C P ++ +PWR EC+ C+C+G +E C++D V +
Sbjct: 308 ECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLN 367
Query: 336 -QGAY--GGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAV----- 387
+G Y GGVC NC +T G NCE C +FR + + C C CDP G++
Sbjct: 368 IRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCV 427
Query: 388 ---PGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPC 444
A G C CK G CD C G+TG C C+C+ LGS+ + PC
Sbjct: 428 KDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGY-----PDCKACNCSGLGSKNEDPC 482
Query: 445 DEESGRCLCLPNVVGPKCDQCAPYHWKLA--SGQGCEPCAC 483
G C+C NV G C +C + L + +GC+ C C
Sbjct: 483 ---FGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC 520
Score = 190 bits (483), Expect = 6e-48
Identities = 125/389 (32%), Positives = 171/389 (43%), Gaps = 89/389 (22%)
Query: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
C C GHA+ C G + C+ +T GP C++C P + P +
Sbjct: 757 CQCFGHAESCDDVTG------------ECLNCKDHTGGPYCDKCLPGFYGEPTKGT---- 800
Query: 310 AHECQRCDC------NGHSETCHFD----------------PAVFAASQGAYG------- 340
+ +CQ C C N S TCH D P ++G +G
Sbjct: 801 SEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGG 860
Query: 341 ----------------GVCDN-------CRDHTEGKNCERCQLHYFRNRRPGASIQETCI 377
G CD+ C+ T G+ CE C YF + A + C
Sbjct: 861 SCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGD----AVDAKNCQ 916
Query: 378 SCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILG 437
C C+ G+ C TGQC C+ +VQG+RCD CK G GL A +GC C+CN G
Sbjct: 917 PCRCNAGGSF-SEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSA--RGCVPCNCNSFG 973
Query: 438 SRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFT 497
S + C EESG+C C P V G KCD+CA ++ G GC C C + L C+ T
Sbjct: 974 S-KSFDC-EESGQCWCQPGVTGKKCDRCAHGYFNFQEG-GCTACEC---SHLGNNCDPKT 1027
Query: 498 GQCPCREGFGGLMCSAAAIRQCPDRTYG-DVATGCRACDCDFRGTEGPGCDKASGRCLCR 556
G+C C G CS +C T+G + TGC+AC+C G+ C+ +G+C C
Sbjct: 1028 GRCICPPNTIGEKCS-----KCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCH 1082
Query: 557 PGLTGPRCDQCQRGYCNRYPVCVACHPCF 585
P +G +C +C RG+ N YP C C CF
Sbjct: 1083 PKFSGAKCTECSRGHWN-YPRCNLC-DCF 1109
Score = 159 bits (403), Expect = 1e-38
Identities = 104/321 (32%), Positives = 137/321 (42%), Gaps = 44/321 (13%)
Query: 277 DVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQ 336
+VC C G +CE C P + G C+ C C GH+E+C
Sbjct: 722 EVCQCPPGYTGSSCESCWPRHRRVNGTIFGGI----CEPCQCFGHAESCD---------- 767
Query: 337 GAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCEC----DPDGAVPGAPC 392
G C NC+DHT G C++C ++ G S E C C C + P
Sbjct: 768 -DVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTS--EDCQPCACPLNIPSNNFSPTCHL 824
Query: 393 DPVTGQCV--CKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCN------ILGSRRDMPC 444
D G C G RC+ C G+ G C C CN I GS C
Sbjct: 825 DRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGS-----C 879
Query: 445 DEESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPC 502
D SG CL C P G C+ CA Y + C+PC C+ S S C+ TGQC C
Sbjct: 880 DSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCEC 939
Query: 503 REGFGGLMCSAAAIRQCPDRTYG-DVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTG 561
R G C +C T+G A GC C+C+ G++ C++ SG+C C+PG+TG
Sbjct: 940 RANVQGQRCD-----KCKAGTFGLQSARGCVPCNCNSFGSKSFDCEE-SGQCWCQPGVTG 993
Query: 562 PRCDQCQRGYCN-RYPVCVAC 581
+CD+C GY N + C AC
Sbjct: 994 KKCDRCAHGYFNFQEGGCTAC 1014
Score = 113 bits (282), Expect = 1e-24
Identities = 72/213 (33%), Positives = 92/213 (43%), Gaps = 28/213 (13%)
Query: 279 CVCQHNTAGPNCERCAP-FYNNR--PWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAAS 335
C C +G +CE C P FY R P G C C CNGHS C DP
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLC--DPET---- 1433
Query: 336 QGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCEC----DPDGAVPGAP 391
+C NC+ HT G CERC L Y+ + + C C C + P
Sbjct: 1434 -----SICQNCQHHTAGDFCERCALGYYGIVK---GLPNDCQQCACPLISSSNNFSPSCV 1485
Query: 392 CDPVTG-QC-VCKEHVQGERCDLCKPGFTGLTYANPQG-CHRCDCNILGSRRDMPCDEES 448
+ + +C C +G+ C+ C PG+TG + NP G C C+C+ GS +PCD +
Sbjct: 1486 AEGLDDYRCTACPRGYEGQYCERCAPGYTG-SPGNPGGSCQECECDPYGS-LPVPCDPVT 1543
Query: 449 GRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPC 481
G C C P G KCD C HW G C C
Sbjct: 1544 GFCTCRPGATGRKCDGCK--HWHAREGWECVFC 1574
Score = 102 bits (254), Expect = 2e-21
Identities = 63/166 (37%), Positives = 81/166 (48%), Gaps = 25/166 (15%)
Query: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
C C+GH+ C P+ CQH+TAG CERCA Y + +G
Sbjct: 1420 CQCNGHSSLCDPETSICQN------------CQHHTAGDFCERCALGY----YGIVKGL- 1462
Query: 310 AHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRN-RRP 368
++CQ+C C S + +F P+ A Y C C EG+ CERC Y + P
Sbjct: 1463 PNDCQQCACPLISSSNNFSPSCVAEGLDDYR--CTACPRGYEGQYCERCAPGYTGSPGNP 1520
Query: 369 GASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCK 414
G S QE CECDP G++P PCDPVTG C C+ G +CD CK
Sbjct: 1521 GGSCQE----CECDPYGSLP-VPCDPVTGFCTCRPGATGRKCDGCK 1561
Score = 93.2 bits (230), Expect = 1e-18
Identities = 69/259 (26%), Positives = 102/259 (39%), Gaps = 50/259 (19%)
Query: 366 RRPGASIQETCISCECDPDGAVPGAPCDPVTGQ--CVCKEHVQGERCDLCKPGF-----T 418
RR S+++ + C G P DP T + C C+ + G+ CD C PGF
Sbjct: 272 RRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWR 331
Query: 419 GLTYANPQGCHRCDCNILGSRRDMPCDEESGR----------------CL-CLPNVVGPK 461
T+ C C+C+ G + DE R C+ C N G
Sbjct: 332 AGTFLTKTECEACNCH--GKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGIN 389
Query: 462 CDQCAPYHWKLAS-----GQGCEPCACDPHNSLSPQCNQ---------FTGQCPCREGFG 507
C+ C ++ + C+PC CDP SL+ C + G C C+ GFG
Sbjct: 390 CETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFG 449
Query: 508 GLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQC 567
G+ C A R Y C+AC+C G++ D G C+C+ + G C +C
Sbjct: 450 GVSCDRCA------RGYTGYPD-CKACNCSGLGSKNE--DPCFGPCICKENVEGGDCSRC 500
Query: 568 QRGYCN-RYPVCVACHPCF 585
+ G+ N + C CF
Sbjct: 501 KSGFFNLQEDNWKGCDECF 519
Score = 89.7 bits (221), Expect = 1e-17
Identities = 67/218 (30%), Positives = 90/218 (41%), Gaps = 31/218 (14%)
Query: 385 GAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQG---------CHRCDCNI 435
G P D + +C C G C+ C PGF L + P G C C CN
Sbjct: 1367 GTTMTPPADLIE-KCDCPLGYSGLSCEACLPGFYRLR-SQPGGRTPGPTLGTCVPCQCNG 1424
Query: 436 LGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAPYHWKLASG--QGCEPCAC---DPHNSL 489
S CD E+ C C + G C++CA ++ + G C+ CAC N+
Sbjct: 1425 HSSL----CDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNF 1480
Query: 490 SPQC---NQFTGQCP-CREGFGGLMCSAAAIRQCPDRTY--GDVATGCRACDCDFRGTEG 543
SP C +C C G+ G C A P T G+ C+ C+CD G+
Sbjct: 1481 SPSCVAEGLDDYRCTACPRGYEGQYCERCA----PGYTGSPGNPGGSCQECECDPYGSLP 1536
Query: 544 PGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVAC 581
CD +G C CRPG TG +CD C+ + CV C
Sbjct: 1537 VPCDPVTGFCTCRPGATGRKCDGCKHWHAREGWECVFC 1574
Score = 77.8 bits (190), Expect = 6e-14
Identities = 57/191 (29%), Positives = 67/191 (35%), Gaps = 41/191 (21%)
Query: 249 SCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
+C C + C PK G C+C NT G C +CAP N G
Sbjct: 1013 ACECSHLGNNCDPKTGR-------------CICPPNTIGEKCSKCAP--NTWGHSITTGC 1057
Query: 309 DAHECQRC-----DCNGHSETCHFDPAVFAASQGAYGGVCDNC-RDHTEGKNCERCQLHY 362
A C CN ++ C+ P G C C R H C C
Sbjct: 1058 KACNCSTVGSLDFQCNVNTGQCNCHPKF-------SGAKCTECSRGHWNYPRCNLCDCFL 1110
Query: 363 FRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTY 422
PG TC D C TGQC CK +V+G CD C+PG GL
Sbjct: 1111 -----PGTD-ATTC-------DSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDA 1157
Query: 423 ANPQGCHRCDC 433
NP GC C C
Sbjct: 1158 KNPLGCSSCYC 1168
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 200 bits (509), Expect = 6e-51
Identities = 145/521 (27%), Positives = 225/521 (43%), Gaps = 88/521 (16%)
Query: 19 QACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYCTQYGEW--------QMKCCKCD 70
QA + +P V L + + ++TCG PE YC Q + C +
Sbjct: 32 QAHQQRGLFPAV--LNLASNALITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRICNQN 89
Query: 71 SRQPHNYYSHRVENVASSSGPMRWWQSQNDVNP-----VSLQLDLDRRFQLQEVMMEF-Q 124
S P+ H + N G WWQS + N V++ LDL + FQ+ V+++
Sbjct: 90 SSNPNQ--RHPITNAID--GKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAAN 145
Query: 125 GPMPAGMLIERSSDFG--KTWRVYQYLAADCTSTFPRVRQGRPQSW---QDVRCQSLPQR 179
P P ++ERS D K W+ + +C + + + P S+ +V C S +
Sbjct: 146 SPRPGNWILERSLDDVEYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSK 205
Query: 180 PNARLNGGKVQLNLMDLVSGIPATQ--SQKIQEVGEITNLRVNFTRLA------------ 225
+ L G++ ++L ++G P+ S ++ E +R+ F R+
Sbjct: 206 IHP-LENGEIHISL---INGRPSADDPSPELLEFTSARYIRLRFQRIRTLNADLMMFAHK 261
Query: 226 ------PVPQRGYHPPSAYYAVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVC 279
P+ R Y YY+V + + G C C+GHA C P + C
Sbjct: 262 DPREIDPIVTRRY-----YYSVKDISVGGMCICYGHARACPLDPATNKSR---------C 307
Query: 280 VCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAAS---- 335
C+HNT G +C++C P ++ +PWR EC+ C+C+G +E C++D V +
Sbjct: 308 ECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLN 367
Query: 336 -QGAY--GGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAV----- 387
+G Y GGVC NC +T G NCE C +FR + + C C CDP G++
Sbjct: 368 IRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCV 427
Query: 388 ---PGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPC 444
A G C CK G CD C G+TG C C+C+ LGS+ + PC
Sbjct: 428 KDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGY-----PDCKACNCSGLGSKNEDPC 482
Query: 445 DEESGRCLCLPNVVGPKCDQCAPYHWKLA--SGQGCEPCAC 483
G C+C NV G C +C + L + +GC+ C C
Sbjct: 483 ---FGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFC 520
Score = 190 bits (483), Expect = 6e-48
Identities = 125/389 (32%), Positives = 171/389 (43%), Gaps = 89/389 (22%)
Query: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
C C GHA+ C G + C+ +T GP C++C P + P +
Sbjct: 757 CQCFGHAESCDDVTG------------ECLNCKDHTGGPYCDKCLPGFYGEPTKGT---- 800
Query: 310 AHECQRCDC------NGHSETCHFD----------------PAVFAASQGAYG------- 340
+ +CQ C C N S TCH D P ++G +G
Sbjct: 801 SEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGG 860
Query: 341 ----------------GVCDN-------CRDHTEGKNCERCQLHYFRNRRPGASIQETCI 377
G CD+ C+ T G+ CE C YF + A + C
Sbjct: 861 SCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGD----AVDAKNCQ 916
Query: 378 SCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILG 437
C C+ G+ C TGQC C+ +VQG+RCD CK G GL A +GC C+CN G
Sbjct: 917 PCRCNAGGSF-SEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSA--RGCVPCNCNSFG 973
Query: 438 SRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFT 497
S + C EESG+C C P V G KCD+CA ++ G GC C C + L C+ T
Sbjct: 974 S-KSFDC-EESGQCWCQPGVTGKKCDRCAHGYFNFQEG-GCTACEC---SHLGNNCDPKT 1027
Query: 498 GQCPCREGFGGLMCSAAAIRQCPDRTYG-DVATGCRACDCDFRGTEGPGCDKASGRCLCR 556
G+C C G CS +C T+G + TGC+AC+C G+ C+ +G+C C
Sbjct: 1028 GRCICPPNTIGEKCS-----KCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCH 1082
Query: 557 PGLTGPRCDQCQRGYCNRYPVCVACHPCF 585
P +G +C +C RG+ N YP C C CF
Sbjct: 1083 PKFSGAKCTECSRGHWN-YPRCNLC-DCF 1109
Score = 159 bits (403), Expect = 1e-38
Identities = 104/321 (32%), Positives = 137/321 (42%), Gaps = 44/321 (13%)
Query: 277 DVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQ 336
+VC C G +CE C P + G C+ C C GH+E+C
Sbjct: 722 EVCQCPPGYTGSSCESCWPRHRRVNGTIFGGI----CEPCQCFGHAESCD---------- 767
Query: 337 GAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCEC----DPDGAVPGAPC 392
G C NC+DHT G C++C ++ G S E C C C + P
Sbjct: 768 -DVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTS--EDCQPCACPLNIPSNNFSPTCHL 824
Query: 393 DPVTGQCV--CKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCN------ILGSRRDMPC 444
D G C G RC+ C G+ G C C CN I GS C
Sbjct: 825 DRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGS-----C 879
Query: 445 DEESGRCL-CLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPC 502
D SG CL C P G C+ CA Y + C+PC C+ S S C+ TGQC C
Sbjct: 880 DSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCEC 939
Query: 503 REGFGGLMCSAAAIRQCPDRTYG-DVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTG 561
R G C +C T+G A GC C+C+ G++ C++ SG+C C+PG+TG
Sbjct: 940 RANVQGQRCD-----KCKAGTFGLQSARGCVPCNCNSFGSKSFDCEE-SGQCWCQPGVTG 993
Query: 562 PRCDQCQRGYCN-RYPVCVAC 581
+CD+C GY N + C AC
Sbjct: 994 KKCDRCAHGYFNFQEGGCTAC 1014
Score = 113 bits (282), Expect = 1e-24
Identities = 72/213 (33%), Positives = 92/213 (43%), Gaps = 28/213 (13%)
Query: 279 CVCQHNTAGPNCERCAP-FYNNR--PWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAAS 335
C C +G +CE C P FY R P G C C CNGHS C DP
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLC--DPET---- 1433
Query: 336 QGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCEC----DPDGAVPGAP 391
+C NC+ HT G CERC L Y+ + + C C C + P
Sbjct: 1434 -----SICQNCQHHTAGDFCERCALGYYGIVK---GLPNDCQQCACPLISSSNNFSPSCV 1485
Query: 392 CDPVTG-QC-VCKEHVQGERCDLCKPGFTGLTYANPQG-CHRCDCNILGSRRDMPCDEES 448
+ + +C C +G+ C+ C PG+TG + NP G C C+C+ GS +PCD +
Sbjct: 1486 AEGLDDYRCTACPRGYEGQYCERCAPGYTG-SPGNPGGSCQECECDPYGS-LPVPCDPVT 1543
Query: 449 GRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPC 481
G C C P G KCD C HW G C C
Sbjct: 1544 GFCTCRPGATGRKCDGCK--HWHAREGWECVFC 1574
Score = 102 bits (254), Expect = 2e-21
Identities = 63/166 (37%), Positives = 81/166 (48%), Gaps = 25/166 (15%)
Query: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
C C+GH+ C P+ CQH+TAG CERCA Y + +G
Sbjct: 1420 CQCNGHSSLCDPETSICQN------------CQHHTAGDFCERCALGY----YGIVKGL- 1462
Query: 310 AHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRN-RRP 368
++CQ+C C S + +F P+ A Y C C EG+ CERC Y + P
Sbjct: 1463 PNDCQQCACPLISSSNNFSPSCVAEGLDDYR--CTACPRGYEGQYCERCAPGYTGSPGNP 1520
Query: 369 GASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCK 414
G S QE CECDP G++P PCDPVTG C C+ G +CD CK
Sbjct: 1521 GGSCQE----CECDPYGSLP-VPCDPVTGFCTCRPGATGRKCDGCK 1561
Score = 93.2 bits (230), Expect = 1e-18
Identities = 69/259 (26%), Positives = 102/259 (39%), Gaps = 50/259 (19%)
Query: 366 RRPGASIQETCISCECDPDGAVPGAPCDPVTGQ--CVCKEHVQGERCDLCKPGF-----T 418
RR S+++ + C G P DP T + C C+ + G+ CD C PGF
Sbjct: 272 RRYYYSVKDISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWR 331
Query: 419 GLTYANPQGCHRCDCNILGSRRDMPCDEESGR----------------CL-CLPNVVGPK 461
T+ C C+C+ G + DE R C+ C N G
Sbjct: 332 AGTFLTKTECEACNCH--GKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGIN 389
Query: 462 CDQCAPYHWKLAS-----GQGCEPCACDPHNSLSPQCNQ---------FTGQCPCREGFG 507
C+ C ++ + C+PC CDP SL+ C + G C C+ GFG
Sbjct: 390 CETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFG 449
Query: 508 GLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQC 567
G+ C A R Y C+AC+C G++ D G C+C+ + G C +C
Sbjct: 450 GVSCDRCA------RGYTGYPD-CKACNCSGLGSKNE--DPCFGPCICKENVEGGDCSRC 500
Query: 568 QRGYCN-RYPVCVACHPCF 585
+ G+ N + C CF
Sbjct: 501 KSGFFNLQEDNWKGCDECF 519
Score = 89.7 bits (221), Expect = 1e-17
Identities = 67/218 (30%), Positives = 90/218 (41%), Gaps = 31/218 (14%)
Query: 385 GAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQG---------CHRCDCNI 435
G P D + +C C G C+ C PGF L + P G C C CN
Sbjct: 1367 GTTMTPPADLIE-KCDCPLGYSGLSCEACLPGFYRLR-SQPGGRTPGPTLGTCVPCQCNG 1424
Query: 436 LGSRRDMPCDEESGRCL-CLPNVVGPKCDQCAPYHWKLASG--QGCEPCAC---DPHNSL 489
S CD E+ C C + G C++CA ++ + G C+ CAC N+
Sbjct: 1425 HSSL----CDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNF 1480
Query: 490 SPQC---NQFTGQCP-CREGFGGLMCSAAAIRQCPDRTY--GDVATGCRACDCDFRGTEG 543
SP C +C C G+ G C A P T G+ C+ C+CD G+
Sbjct: 1481 SPSCVAEGLDDYRCTACPRGYEGQYCERCA----PGYTGSPGNPGGSCQECECDPYGSLP 1536
Query: 544 PGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVAC 581
CD +G C CRPG TG +CD C+ + CV C
Sbjct: 1537 VPCDPVTGFCTCRPGATGRKCDGCKHWHAREGWECVFC 1574
Score = 77.8 bits (190), Expect = 6e-14
Identities = 57/191 (29%), Positives = 67/191 (35%), Gaps = 41/191 (21%)
Query: 249 SCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
+C C + C PK G C+C NT G C +CAP N G
Sbjct: 1013 ACECSHLGNNCDPKTGR-------------CICPPNTIGEKCSKCAP--NTWGHSITTGC 1057
Query: 309 DAHECQRC-----DCNGHSETCHFDPAVFAASQGAYGGVCDNC-RDHTEGKNCERCQLHY 362
A C CN ++ C+ P G C C R H C C
Sbjct: 1058 KACNCSTVGSLDFQCNVNTGQCNCHPKF-------SGAKCTECSRGHWNYPRCNLCDCFL 1110
Query: 363 FRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTY 422
PG TC D C TGQC CK +V+G CD C+PG GL
Sbjct: 1111 -----PGTD-ATTC-------DSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDA 1157
Query: 423 ANPQGCHRCDC 433
NP GC C C
Sbjct: 1158 KNPLGCSSCYC 1168
>gi|5453810 netrin 3 [Homo sapiens]
Length = 580
Score = 196 bits (498), Expect = 1e-49
Identities = 127/414 (30%), Positives = 196/414 (47%), Gaps = 45/414 (10%)
Query: 16 HAQQACSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYCTQYGEWQMKCCKCDSRQPH 75
H + RG C P + + +GR + ASSTCG +P T CD+ P
Sbjct: 31 HDEGGAPRG-CVPGLVNAALGRE--VLASSTCG--RPATRA------------CDASDPR 73
Query: 76 NYYSHRV-ENVASSSGPMRWWQSQNDVNP--VSLQLDLDRRFQLQEVMMEFQGPMPAGML 132
+S + + ++ P+ W P V+L + L + F+L V + F PA +
Sbjct: 74 RAHSPALLTSPGGTASPLCWRSESLPRAPLNVTLTVPLGKAFELVFVSLRFCSAPPASVA 133
Query: 133 IERSSDFGKTWRVYQYLAADCTSTFPRV---RQGRPQSWQDVRCQSLP-QRPNARLNGGK 188
+ +S D G++W + ++ C + R+ G + C P +P+ G
Sbjct: 134 LLKSQDHGRSWAPLGFFSSHCDLDYGRLPAPANGPAGPGPEALCFPAPLAQPDG---SGL 190
Query: 189 VQLNLMDLVS-GIPATQSQKIQEVGEITNLRVNFTRLA----PVPQRGYHPPSAYYAVSQ 243
+ ++ D G+ S +Q+ T++RV TR + P P S YA +
Sbjct: 191 LAFSMQDSSPPGLDLDSSPVLQDWVTATDVRVVLTRPSTAGDPRDMEAVVPYS--YAATD 248
Query: 244 LRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWR 303
L++ G C C+GHA RC Q H +C C+H T GP+C RC PFY +RPW+
Sbjct: 249 LQVGGRCKCNGHASRCL----------LDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQ 298
Query: 304 PAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYF 363
A +++H C C CNGH+ C F+ ++ S GGVC NCR +T G++C C+ ++
Sbjct: 299 RATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFY 358
Query: 364 RNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGF 417
R+ S + C +C+C P GA G C+ TGQC CK+ V G C+ C PGF
Sbjct: 359 RDPGRALSDRRACRACDCHPVGAA-GKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411
Score = 70.5 bits (171), Expect = 9e-12
Identities = 51/183 (27%), Positives = 80/183 (43%), Gaps = 37/183 (20%)
Query: 430 RCDCN------ILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYH----WKLASGQ--- 476
RC CN +L ++ + CD C GP C +C P++ W+ A+ +
Sbjct: 254 RCKCNGHASRCLLDTQGHLICD-------CRHGTEGPDCGRCKPFYCDRPWQRATARESH 306
Query: 477 GCEPCACDPHNS---LSPQCNQFTGQ------CPCREGFGGLMCSAA--AIRQCPDRTYG 525
C C+C+ H + + + +G+ CR G C + P R
Sbjct: 307 ACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALS 366
Query: 526 DVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGY-CNRYPVCVACHPC 584
D CRACDC G G C++ +G+C C+ G+TG C++C G+ +R PV PC
Sbjct: 367 D-RRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVA----PC 421
Query: 585 FQT 587
+T
Sbjct: 422 VKT 424
Score = 69.3 bits (168), Expect = 2e-11
Identities = 43/135 (31%), Positives = 55/135 (40%), Gaps = 18/135 (13%)
Query: 399 CVCKEHVQGERCDLCKPGFTG-----LTYANPQGCHRCDCN--ILGSRRDMPCDEESGR- 450
C C+ +G C CKP + T C C CN R +M SGR
Sbjct: 274 CDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRR 333
Query: 451 ----CL-CLPNVVGPKCDQCAPYHWK-----LASGQGCEPCACDPHNSLSPQCNQFTGQC 500
CL C N G C C ++ L+ + C C C P + CNQ TGQC
Sbjct: 334 SGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQC 393
Query: 501 PCREGFGGLMCSAAA 515
PC++G GL C+ A
Sbjct: 394 PCKDGVTGLTCNRCA 408
>gi|164414431 netrin G1 isoform 1 [Homo sapiens]
Length = 539
Score = 162 bits (409), Expect = 2e-39
Identities = 131/489 (26%), Positives = 212/489 (43%), Gaps = 87/489 (17%)
Query: 25 ACYPPVGDLLVGRTRFLRASS-----TCGLTKPETYCTQYGEWQMKCCKCDSRQPHNYYS 79
AC P D+ T++L+ TCG PET+C G M +CD+ P +
Sbjct: 49 ACQPESTDM----TKYLKVKLDPPDITCG-DPPETFCAM-GNPYMCNNECDASTPE--LA 100
Query: 80 HRVENVASSSG--PMRWWQSQNDVN-----PVSLQLDLDRRFQLQE-VMMEFQGPMPAGM 131
H E + G P +WQS V++ L + +L + +++ F+ P M
Sbjct: 101 HPPELMFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPDQM 160
Query: 132 LIERSSDFGKTWRVYQYLAADCTSTF----PRVRQGRPQSWQDVRCQ---SLPQRPNARL 184
++E+S D+G+TW+ YQY A DC F V+ + ++ C S N+++
Sbjct: 161 ILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNSKI 220
Query: 185 NGGKVQ-----------LNLMDLVSGIPATQSQKIQEVGEITNLRVNFTRLA--PVPQRG 231
+++ N+ L + T+ K+++ +T+LR+ R A +
Sbjct: 221 IHFEIKDRFAFFAGPRLRNMASLYGQLDTTK--KLRDFFTVTDLRIRLLRPAVGEIFVDE 278
Query: 232 YHPPSAYYAVSQLRLQGSCFCHGHADRCAPKPGASAGPSTAVQVHD----VCVCQHNTAG 287
H +YA+S ++++G C C+ HA C V+D C C+HNT G
Sbjct: 279 LHLARYFYAISDIKVRGRCKCNLHATVC---------------VYDNSKLTCECEHNTTG 323
Query: 288 PNCERCAPFYNNRPWRPAE-----GQDAHEC-------QRCDCNGHSETCHFDPAVFAAS 335
P+C +C Y RPW P A+ C C+C GHS C + +
Sbjct: 324 PDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTV- 382
Query: 336 QGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPV 395
+C +C+ +T G++CE C+L YFRN + CI C C+P G++ C+
Sbjct: 383 ------ICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDR-CNG- 434
Query: 396 TGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLP 455
+G C CK G +CD C PG + P + CD +L + C + RCLC
Sbjct: 435 SGFCECKTGTTGPKCDECLPGNSWHYGCQP---NVCDNELLHCQNGGTC-HNNVRCLCPA 490
Query: 456 NVVGPKCDQ 464
G C++
Sbjct: 491 AYTGILCEK 499
Score = 57.4 bits (137), Expect = 8e-08
Identities = 48/193 (24%), Positives = 73/193 (37%), Gaps = 33/193 (17%)
Query: 399 CVCKEHVQGERCDLCKPGFTGLTYAN------PQGCHRCDCNILGSRRDMPCDEESGRCL 452
C C+ + G C CK + G ++ P+G + S + C S RC
Sbjct: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCS 374
Query: 453 ------------CLPNVVGPKCDQCAPYHWKLASGQ-----GCEPCACDPHNSLSPQCNQ 495
C N G C+ C +++ AS Q C C C+P S+ +CN
Sbjct: 375 YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCNG 434
Query: 496 FTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCR--ACDCDFRGTEGPGCDKASGRC 553
+G C C+ G G C P ++ GC+ CD + + G + RC
Sbjct: 435 -SGFCECKTGTTGPKCDECL----PGNSWH---YGCQPNVCDNELLHCQNGGTCHNNVRC 486
Query: 554 LCRPGLTGPRCDQ 566
LC TG C++
Sbjct: 487 LCPAAYTGILCEK 499
Score = 46.6 bits (109), Expect = 1e-04
Identities = 46/178 (25%), Positives = 62/178 (34%), Gaps = 33/178 (18%)
Query: 430 RCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAP-YHWKLASGQGCEPCACDPHNS 488
RC CN+ + D C C N GP C +C Y + S P N+
Sbjct: 296 RCKCNLHATV--CVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANT 353
Query: 489 LSPQCNQFTGQCPC-----REGFGGLMCSAAAIRQCPDRTYGDVATGCRA---------- 533
P + G C C R + L+ + + C T G CR
Sbjct: 354 CIPSISSI-GNCECFGHSNRCSYIDLLNTVICV-SCKHNTRGQHCELCRLGYFRNASAQL 411
Query: 534 --------CDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHP 583
C C+ G+ C+ SG C C+ G TGP+CD+C G Y C P
Sbjct: 412 DDENVCIECYCNPLGSIHDRCN-GSGFCECKTGTTGPKCDECLPGNSWHY----GCQP 464
>gi|24308065 netrin 5 [Homo sapiens]
Length = 489
Score = 156 bits (395), Expect = 1e-37
Identities = 78/196 (39%), Positives = 100/196 (51%), Gaps = 25/196 (12%)
Query: 235 PSAYYAVSQLR-------------LQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVC 281
P A A S LR L+G C CHGHA RCA A A P C C
Sbjct: 129 PKATVAASHLRVEFGGQAGLAAAGLRGRCQCHGHAARCA----ARARPPR-------CHC 177
Query: 282 QHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGG 341
+H+T GP CE C P + + PWRPA + H C C CN H+ C F+ +F S G GG
Sbjct: 178 RHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGG 237
Query: 342 VCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVC 401
VC+ CR HT G++C CQ ++R+ + C +C+C P GA G C+ +GQC C
Sbjct: 238 VCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGAT-GGTCNQTSGQCTC 296
Query: 402 KEHVQGERCDLCKPGF 417
K V G C+ C PG+
Sbjct: 297 KLGVTGLTCNRCGPGY 312
Score = 71.2 bits (173), Expect = 5e-12
Identities = 53/181 (29%), Positives = 74/181 (40%), Gaps = 37/181 (20%)
Query: 416 GFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYH----WK 471
G GL A +G RC C+ G RC C + GP C+ C P H W+
Sbjct: 144 GQAGLAAAGLRG--RCQCH--GHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWR 199
Query: 472 LASGQG---CEPCACDPHNSLSPQCN-----------QFTGQCP-CREGFGGLMCSAAAI 516
A+ + C PC+C+ H + +C + G C CR G C
Sbjct: 200 PATPRHPHPCLPCSCNQH---ARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHC----- 251
Query: 517 RQCPDRTYGDVAT------GCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRG 570
C + D + CRAC C G G C++ SG+C C+ G+TG C++C G
Sbjct: 252 HYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPG 311
Query: 571 Y 571
Y
Sbjct: 312 Y 312
>gi|190014607 netrin G2 [Homo sapiens]
Length = 530
Score = 152 bits (383), Expect = 2e-36
Identities = 122/464 (26%), Positives = 196/464 (42%), Gaps = 72/464 (15%)
Query: 46 TCGLTKPETYCTQYGEWQMKCCKCDSRQPHNYYSHRVENVASSSGPMRWWQS---QNDVN 102
TCG PE +C+ + + +CD+ P + R+ G +WQS +
Sbjct: 60 TCG-DPPERFCSHENPY-LCSNECDASNPDLAHPPRLMFDKEEEGLATYWQSITWSRYPS 117
Query: 103 PVSLQLDLDRRFQLQ---EVMMEFQGPMPAGMLIERSSDFGKTWRVYQYLAADCTSTFP- 158
P+ + L ++ +V+M F+ P M++E+S D G+TW+ YQ+ A DC F
Sbjct: 118 PLEANITLSWNKTVELTDDVVMTFEYGRPTVMVLEKSLDNGRTWQPYQFYAEDCMEAFGM 177
Query: 159 ---RVRQGRPQSWQDVRCQS---------------LPQRPNARLNGGKVQLNLMDLVSGI 200
R R S V C R + G N+ +L + +
Sbjct: 178 SARRARDMSSSSAHRVLCTEEYSRWAGSKKEKHVRFEVRDRFAIFAGPDLRNMDNLYTRL 237
Query: 201 PATQSQKIQEVGEITNLRVNFTR--LAPVPQRGYHPPSAYYAVSQLRLQGSCFCHGHADR 258
+ + K E +T+LR+ R L + + +YA+S + + G C C+ HA+
Sbjct: 238 ESAKGLK--EFFTLTDLRMRLLRPALGGTYVQRENLYKYFYAISNIEVIGRCKCNLHANL 295
Query: 259 CAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWR-----------PAEG 307
C+ + G+ C C+HNT GP+C +C + R WR P
Sbjct: 296 CSMREGSLQ-----------CECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNAC 344
Query: 308 QDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRR 367
A C+C GHS C + + + C +C+ +T G++C+ C+L Y+RN
Sbjct: 345 ATAGSFGNCECYGHSNRCSYIDFLNVVT-------CVSCKHNTRGQHCQHCRLGYYRNGS 397
Query: 368 PGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQG 427
+ CI C C+ G+V C+ TG C C+E G +CD C P T+ QG
Sbjct: 398 AELDDENVCIECNCNQIGSVHDR-CNE-TGFCECREGAAGPKCDDCLP-----THYWRQG 450
Query: 428 CHR--CDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQ--CAP 467
C+ CD + L + C ++ RC C G +C+Q C P
Sbjct: 451 CYPNVCDDDQLLCQNGGTC-LQNQRCACPRGYTGVRCEQPRCDP 493
Score = 80.9 bits (198), Expect = 7e-15
Identities = 62/218 (28%), Positives = 91/218 (41%), Gaps = 38/218 (17%)
Query: 315 RCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHY-FRNRRPGASIQ 373
RC CN H+ C G + C +T G +C +C+ ++ R+ R G+ +
Sbjct: 286 RCKCNLHANLCSMRE----------GSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLP 335
Query: 374 ETCISCE-CDPDGAVPGAPCDPVTGQCV------------CKEHVQGERCDLCKPGF--T 418
S C G+ C + +C CK + +G+ C C+ G+
Sbjct: 336 LPHGSPNACATAGSFGNCECYGHSNRCSYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRN 395
Query: 419 GLTYANPQG-CHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYH-WKLASGQ 476
G + + C C+CN +GS D C+E +G C C GPKCD C P H W+ Q
Sbjct: 396 GSAELDDENVCIECNCNQIGSVHDR-CNE-TGFCECREGAAGPKCDDCLPTHYWR----Q 449
Query: 477 GCEPCACDPHNSLSPQ---CNQFTGQCPCREGFGGLMC 511
GC P CD L C Q +C C G+ G+ C
Sbjct: 450 GCYPNVCDDDQLLCQNGGTCLQ-NQRCACPRGYTGVRC 486
Score = 67.4 bits (163), Expect = 8e-11
Identities = 54/192 (28%), Positives = 68/192 (35%), Gaps = 30/192 (15%)
Query: 398 QCVCKEHVQGERCDLCKPGF------TGLTYANPQGCHRCDCNILGSRRDMPCDEESGRC 451
QC C+ + G C CK F G P G C GS + C S RC
Sbjct: 304 QCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNA-CATAGSFGNCECYGHSNRC 362
Query: 452 L------------CLPNVVGPKCDQCAPYHWKLASGQ-----GCEPCACDPHNSLSPQCN 494
C N G C C +++ S + C C C+ S+ +CN
Sbjct: 363 SYIDFLNVVTCVSCKHNTRGQHCQHCRLGYYRNGSAELDDENVCIECNCNQIGSVHDRCN 422
Query: 495 QFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCL 554
+ TG C CREG G C C Y CD D + G + RC
Sbjct: 423 E-TGFCECREGAAGPKCD-----DCLPTHYWRQGCYPNVCDDDQLLCQNGGTCLQNQRCA 476
Query: 555 CRPGLTGPRCDQ 566
C G TG RC+Q
Sbjct: 477 CPRGYTGVRCEQ 488
Score = 47.8 bits (112), Expect = 6e-05
Identities = 42/164 (25%), Positives = 60/164 (36%), Gaps = 34/164 (20%)
Query: 430 RCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYH----WKLASGQGC---EPCA 482
RC CN+ + M E S +C C N GP C +C W+ S P A
Sbjct: 286 RCKCNLHANLCSMR--EGSLQCECEHNTTGPDCGKCKKNFRTRSWRAGSYLPLPHGSPNA 343
Query: 483 CDPHNSLSP-QCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRA-------- 533
C S +C + +C + + C + C T G CR
Sbjct: 344 CATAGSFGNCECYGHSNRCSYIDFLNVVTCVS-----CKHNTRGQHCQHCRLGYYRNGSA 398
Query: 534 ----------CDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQC 567
C+C+ G+ C++ +G C CR G GP+CD C
Sbjct: 399 ELDDENVCIECNCNQIGSVHDRCNE-TGFCECREGAAGPKCDDC 441
>gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]
Length = 1193
Score = 138 bits (347), Expect = 4e-32
Identities = 169/785 (21%), Positives = 306/785 (38%), Gaps = 82/785 (10%)
Query: 351 EGKNCERCQLHYFRNRRPGASIQE--TCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGE 408
+G+ C+ C Y +R A + TCI C C GA CDP TG C +
Sbjct: 389 KGQFCQDCASGY---KRDSARLGPFGTCIPCNCQGGGA-----CDPDTGDCYSGDENPDI 440
Query: 409 RCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPY 468
C C GF + +P+ C C C+ S MP EE C P V G +C+ CA
Sbjct: 441 ECADCPIGFYNDPH-DPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADG 499
Query: 469 HWKLASGQ-----GCEPCACDPH--NSLSPQCNQFTGQC-PCREGFGGLMCSAAAIRQCP 520
++ G+ C+PC C+ + S S C++ TG+C C G+ C
Sbjct: 500 YFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFG 559
Query: 521 DRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVA 580
D + A CRAC+C+ G+E GC ++ G C+C+PG GP C+ +
Sbjct: 560 DPLAPNPADKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH----------GAFS 608
Query: 581 CHPCFQTYDADLREQALRFGRLRNATASLWSGPG-LEDRGLASRILDAKSKIEQI--RAV 637
C C+ + + + R+ + G G + D L R+ A+ ++ I A
Sbjct: 609 CPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQ 668
Query: 638 LSSPAVTE--QEVAQVASAILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTM 695
+S A ++A+V S S + L L++ + E +L ++ R + L+T
Sbjct: 669 ISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTV---ERVRALGSQYQNRVRDTHRLITQ 725
Query: 696 YQRKREQFE------KISSAD----PSGAFRMLSTAYEQSAQAAQQVSDSSRLLDQLRDS 745
Q + E I ++D P+G + A + + S+ +L + D
Sbjct: 726 MQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDY 785
Query: 746 RREAERLVRQA---GGGGGTGSPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCP 802
++A LVR+A G G G+GSP ++ + L +L + Q
Sbjct: 786 SKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAE------- 838
Query: 803 GELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLR------GFNAQLQRTRQMIRAA 856
D R + R G + QV E R ++ + R +
Sbjct: 839 ---IEADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRT 895
Query: 857 EESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAV 916
+++ + AQ+L + R + ++ + R L + ++ L+ + ++ + + +
Sbjct: 896 QKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNL 955
Query: 917 LALWLPTDS--ATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAH 974
L D+ A + M + I+ ++ + Q ++ + A A+ A
Sbjct: 956 REFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEAL 1015
Query: 975 AVEGQVEDVVGNLRQGTVALQEAQDTMQGT---SRSLRLIQDRVAEVQQVLRPAEKLVTS 1031
+ ++E +G+L EA T G + L ++ + EV+ L E +
Sbjct: 1016 EISSEIEQEIGSLN------LEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDT 1069
Query: 1032 MTKQLGDFWTRMEELRHQARQQGAEAVQAQQLAEG---ASEQALSA-QEGFERIKQKYAE 1087
+ T +++ +A+ G +G +Q LS +EG ++QK +
Sbjct: 1070 NMDAVQMVITEAQKVDTRAKNAGVTIQDTLNTLDGLLHLMDQPLSVDEEGLVLLEQKLSR 1129
Query: 1088 LKDRL 1092
K ++
Sbjct: 1130 AKTQI 1134
Score = 124 bits (312), Expect = 4e-28
Identities = 71/183 (38%), Positives = 99/183 (54%), Gaps = 26/183 (14%)
Query: 316 CDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQET 375
CDCNG S C FD + Q G C NC D+T+G +CE+C+ ++R+R ++
Sbjct: 28 CDCNGKSRQCIFDRELHR--QTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRE-----RDR 80
Query: 376 CISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC------- 428
C+ C C+ G++ A CD +G+C CK V G RCD C PGF LT A GC
Sbjct: 81 CLPCNCNSKGSL-SARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLL 135
Query: 429 -HRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASG--QGCEPCACDP 485
+CDC+ G PCD +GRC+C P V G +CD+C ++ L G +GC C C
Sbjct: 136 DSKCDCDPAGIAG--PCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYG 191
Query: 486 HNS 488
H++
Sbjct: 192 HSA 194
Score = 91.3 bits (225), Expect = 5e-18
Identities = 52/159 (32%), Positives = 71/159 (44%), Gaps = 31/159 (19%)
Query: 281 CQHNTAGPNCERCAP-FYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAY 339
C NT G +CE+C FY +R + C C+CN S+G+
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHR--------ERDRCLPCNCN---------------SKGSL 92
Query: 340 GGVCDN-----CRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDP 394
CDN C+ G C+RC + G + + + +CD D A PCD
Sbjct: 93 SARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCD- 151
Query: 395 VTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDC 433
G+CVCK V GERCD C+ G+ L NP+GC +C C
Sbjct: 152 -AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 89.4 bits (220), Expect = 2e-17
Identities = 56/159 (35%), Positives = 74/159 (46%), Gaps = 27/159 (16%)
Query: 431 CDCNILGSRRDMPCDEE-------SGRCL-CLPNVVGPKCDQCAPYHWKLASGQGCEPCA 482
CDCN G R D E RCL C N G C++C ++ C PC
Sbjct: 28 CDCN--GKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCN 85
Query: 483 CDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRA--------C 534
C+ SLS +C+ +G+C C+ G G C +C + GC C
Sbjct: 86 CNSKGSLSARCDN-SGRCSCKPGVTGARCD-----RCLPGFHMLTDAGCTQDQRLLDSKC 139
Query: 535 DCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCN 573
DCD G GP CD +GRC+C+P +TG RCD+C+ GY N
Sbjct: 140 DCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYYN 175
Score = 77.8 bits (190), Expect = 6e-14
Identities = 71/247 (28%), Positives = 93/247 (37%), Gaps = 42/247 (17%)
Query: 259 CAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDC 318
C + G + P T C C C + N P D C+ C C
Sbjct: 416 CNCQGGGACDPDTGD-----CYSGDENPDIECADCPIGFYNDP------HDPRSCKPCPC 464
Query: 319 -NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCI 377
NG S C P VC+NC G CE C YF + C
Sbjct: 465 HNGFS--CSVMPETEEV-------VCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQ 515
Query: 378 SCECDPDGAVPGAP--CDPVTGQCV-CKEHVQGERCDLCKPGFTGLTYA-NP-QGCHRCD 432
C+C+ + P A CD +TG+C+ C + G CD CK G+ G A NP C C+
Sbjct: 516 PCQCN-NNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACN 574
Query: 433 CNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQ 492
CN +GS + C G C+C P GP C+ A C C +N + Q
Sbjct: 575 CNPMGS-EPVGC-RSDGTCVCKPGFGGPNCEHGA---------FSCPAC----YNQVKIQ 619
Query: 493 CNQFTGQ 499
+QF Q
Sbjct: 620 MDQFMQQ 626
Score = 44.3 bits (103), Expect = 7e-04
Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 9/68 (13%)
Query: 258 RCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCD 317
+C P AGP A + CVC+ G C+RC Y N +G + C +C
Sbjct: 138 KCDCDPAGIAGPCDAGR----CVCKPAVTGERCDRCRSGYYN-----LDGGNPEGCTQCF 188
Query: 318 CNGHSETC 325
C GHS +C
Sbjct: 189 CYGHSASC 196
Score = 41.6 bits (96), Expect = 0.004
Identities = 35/134 (26%), Positives = 46/134 (34%), Gaps = 24/134 (17%)
Query: 253 HGHADRCAPKPGASAGPSTA-VQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAH 311
H DRC P S G +A C C+ G C+RC P ++
Sbjct: 75 HRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRL 134
Query: 312 ECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDN----CRDHTEGKNCERCQLHYFRNRR 367
+CDC DPA A G CD C+ G+ C+RC+ Y+
Sbjct: 135 LDSKCDC---------DPAGIA-------GPCDAGRCVCKPAVTGERCDRCRSGYY---N 175
Query: 368 PGASIQETCISCEC 381
E C C C
Sbjct: 176 LDGGNPEGCTQCFC 189
>gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]
Length = 1111
Score = 135 bits (340), Expect = 2e-31
Identities = 158/731 (21%), Positives = 288/731 (39%), Gaps = 84/731 (11%)
Query: 351 EGKNCERCQLHYFRNRRPGASIQE--TCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGE 408
+G+ C+ C Y +R A + TCI C C GA CDP TG C +
Sbjct: 389 KGQFCQDCASGY---KRDSARLGPFGTCIPCNCQGGGA-----CDPDTGDCYSGDENPDI 440
Query: 409 RCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPY 468
C C GF + +P+ C C C+ S MP EE C P V G +C+ CA
Sbjct: 441 ECADCPIGFYNDPH-DPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADG 499
Query: 469 HWKLASGQ-----GCEPCACDPH--NSLSPQCNQFTGQC-PCREGFGGLMCSAAAIRQCP 520
++ G+ C+PC C+ + S S C++ TG+C C G+ C
Sbjct: 500 YFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFG 559
Query: 521 DRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVA 580
D + A CRAC+C+ G+E GC ++ G C+C+PG GP C+ +
Sbjct: 560 DPLAPNPADKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH----------GAFS 608
Query: 581 CHPCFQTYDADLREQALRFGRLRNATASLWSGPG-LEDRGLASRILDAKSKIEQI--RAV 637
C C+ + + + R+ + G G + D L R+ A+ ++ I A
Sbjct: 609 CPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQ 668
Query: 638 LSSPAVTE--QEVAQVASAILSLRRTLQGLQLDLPLEEETLSLPRDLESLDRSFNGLLTM 695
+S A ++A+V S S + L L++ + E +L ++ R + L+T
Sbjct: 669 ISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTV---ERVRALGSQYQNRVRDTHRLITQ 725
Query: 696 YQRKREQFE------KISSAD----PSGAFRMLSTAYEQSAQAAQQVSDSSRLLDQLRDS 745
Q + E I ++D P+G + A + + S+ +L + D
Sbjct: 726 MQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDY 785
Query: 746 RREAERLVRQA---GGGGGTGSPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCP 802
++A LVR+A G G G+GSP ++ + L +L + Q
Sbjct: 786 SKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAE------- 838
Query: 803 GELCPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLR------GFNAQLQRTRQMIRAA 856
D R + R G + QV E R ++ + R +
Sbjct: 839 ---IEADRSYQHSLRLLDSVSRLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRT 895
Query: 857 EESASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAV 916
+++ + AQ+L + R + ++ + R L + ++ L+ + ++ + + +
Sbjct: 896 QKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNL 955
Query: 917 LALWLPTDS--ATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAH 974
L D+ A + M + I+ ++ + Q ++ + A A+ A
Sbjct: 956 REFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEAL 1015
Query: 975 AVEGQVEDVVGNLR-------QGTVALQEAQDTMQGTSRSLRLIQDR--------VAEVQ 1019
+ ++E +G+L G +A+++ +++ R + +R + VQ
Sbjct: 1016 EISSEIEQEIGSLNLEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQ 1075
Query: 1020 QVLRPAEKLVT 1030
V+ A+K+ T
Sbjct: 1076 MVITEAQKVDT 1086
Score = 124 bits (312), Expect = 4e-28
Identities = 71/183 (38%), Positives = 99/183 (54%), Gaps = 26/183 (14%)
Query: 316 CDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQET 375
CDCNG S C FD + Q G C NC D+T+G +CE+C+ ++R+R ++
Sbjct: 28 CDCNGKSRQCIFDRELHR--QTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRE-----RDR 80
Query: 376 CISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGC------- 428
C+ C C+ G++ A CD +G+C CK V G RCD C PGF LT A GC
Sbjct: 81 CLPCNCNSKGSL-SARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDA---GCTQDQRLL 135
Query: 429 -HRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASG--QGCEPCACDP 485
+CDC+ G PCD +GRC+C P V G +CD+C ++ L G +GC C C
Sbjct: 136 DSKCDCDPAGIAG--PCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYG 191
Query: 486 HNS 488
H++
Sbjct: 192 HSA 194
Score = 91.3 bits (225), Expect = 5e-18
Identities = 52/159 (32%), Positives = 71/159 (44%), Gaps = 31/159 (19%)
Query: 281 CQHNTAGPNCERCAP-FYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAY 339
C NT G +CE+C FY +R + C C+CN S+G+
Sbjct: 56 CNDNTDGIHCEKCKNGFYRHR--------ERDRCLPCNCN---------------SKGSL 92
Query: 340 GGVCDN-----CRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDP 394
CDN C+ G C+RC + G + + + +CD D A PCD
Sbjct: 93 SARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCD- 151
Query: 395 VTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDC 433
G+CVCK V GERCD C+ G+ L NP+GC +C C
Sbjct: 152 -AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFC 189
Score = 89.4 bits (220), Expect = 2e-17
Identities = 56/159 (35%), Positives = 74/159 (46%), Gaps = 27/159 (16%)
Query: 431 CDCNILGSRRDMPCDEE-------SGRCL-CLPNVVGPKCDQCAPYHWKLASGQGCEPCA 482
CDCN G R D E RCL C N G C++C ++ C PC
Sbjct: 28 CDCN--GKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCN 85
Query: 483 CDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRA--------C 534
C+ SLS +C+ +G+C C+ G G C +C + GC C
Sbjct: 86 CNSKGSLSARCDN-SGRCSCKPGVTGARCD-----RCLPGFHMLTDAGCTQDQRLLDSKC 139
Query: 535 DCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCN 573
DCD G GP CD +GRC+C+P +TG RCD+C+ GY N
Sbjct: 140 DCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYYN 175
Score = 77.8 bits (190), Expect = 6e-14
Identities = 71/247 (28%), Positives = 93/247 (37%), Gaps = 42/247 (17%)
Query: 259 CAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDC 318
C + G + P T C C C + N P D C+ C C
Sbjct: 416 CNCQGGGACDPDTGD-----CYSGDENPDIECADCPIGFYNDP------HDPRSCKPCPC 464
Query: 319 -NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCI 377
NG S C P VC+NC G CE C YF + C
Sbjct: 465 HNGFS--CSVMPETEEV-------VCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQ 515
Query: 378 SCECDPDGAVPGAP--CDPVTGQCV-CKEHVQGERCDLCKPGFTGLTYA-NP-QGCHRCD 432
C+C+ + P A CD +TG+C+ C + G CD CK G+ G A NP C C+
Sbjct: 516 PCQCN-NNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACN 574
Query: 433 CNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQ 492
CN +GS + C G C+C P GP C+ A C C +N + Q
Sbjct: 575 CNPMGS-EPVGC-RSDGTCVCKPGFGGPNCEHGA---------FSCPAC----YNQVKIQ 619
Query: 493 CNQFTGQ 499
+QF Q
Sbjct: 620 MDQFMQQ 626
Score = 44.3 bits (103), Expect = 7e-04
Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 9/68 (13%)
Query: 258 RCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCD 317
+C P AGP A + CVC+ G C+RC Y N +G + C +C
Sbjct: 138 KCDCDPAGIAGPCDAGR----CVCKPAVTGERCDRCRSGYYN-----LDGGNPEGCTQCF 188
Query: 318 CNGHSETC 325
C GHS +C
Sbjct: 189 CYGHSASC 196
Score = 41.6 bits (96), Expect = 0.004
Identities = 35/134 (26%), Positives = 46/134 (34%), Gaps = 24/134 (17%)
Query: 253 HGHADRCAPKPGASAGPSTA-VQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAH 311
H DRC P S G +A C C+ G C+RC P ++
Sbjct: 75 HRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRL 134
Query: 312 ECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDN----CRDHTEGKNCERCQLHYFRNRR 367
+CDC DPA A G CD C+ G+ C+RC+ Y+
Sbjct: 135 LDSKCDC---------DPAGIA-------GPCDAGRCVCKPAVTGERCDRCRSGYY---N 175
Query: 368 PGASIQETCISCEC 381
E C C C
Sbjct: 176 LDGGNPEGCTQCFC 189
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 120 bits (302), Expect = 6e-27
Identities = 69/194 (35%), Positives = 88/194 (45%), Gaps = 35/194 (18%)
Query: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
C CHGH++ C P+ GA G CQH+T GP CE+C P Y + A+
Sbjct: 1159 CSCHGHSEACEPETGACQG------------CQHHTEGPRCEQCQPGY----YGDAQRGT 1202
Query: 310 AHECQRCDCNGHSETCHFDPAVFAASQGAY-----GGVCDNCRDHTEGKNCERCQLHYFR 364
+CQ C C G DPA A+ + CD C G++CERC Y+
Sbjct: 1203 PQDCQLCPCYG-------DPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYG 1255
Query: 365 NRRPGASIQETC-----ISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTG 419
N G Q I C CDP G+V + CD GQC CK V+G C C+P
Sbjct: 1256 NPSQGQPCQRDSQVPGPIGCNCDPQGSV-SSQCD-AAGQCQCKAQVEGLTCSHCRPHHFH 1313
Query: 420 LTYANPQGCHRCDC 433
L+ +NP GC C C
Sbjct: 1314 LSASNPDGCLPCFC 1327
Score = 110 bits (274), Expect = 1e-23
Identities = 74/236 (31%), Positives = 97/236 (41%), Gaps = 44/236 (18%)
Query: 268 GPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHF 327
G A++V C C GP+C+ C Y P G C+RC C+GHSE C
Sbjct: 1116 GQDPALEVEQ-CSCPPGYRGPSCQDCDTGYTRTP----SGLYLGTCERCSCHGHSEACEP 1170
Query: 328 DPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCEC--DPDG 385
+ G C C+ HTEG CE+CQ Y+ + + G + C C C DP
Sbjct: 1171 ET-----------GACQGCQHHTEGPRCEQCQPGYYGDAQRGT--PQDCQLCPCYGDPAA 1217
Query: 386 AVPGAPC----DPVTGQCVCKEHVQGERCDLCKPGFTGLTYANP---QGCHR-------- 430
C D C G C+ C PG+ Y NP Q C R
Sbjct: 1218 GQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGY----YGNPSQGQPCQRDSQVPGPI 1273
Query: 431 -CDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASG--QGCEPCAC 483
C+C+ GS CD +G+C C V G C C P+H+ L++ GC PC C
Sbjct: 1274 GCNCDPQGSVSSQ-CD-AAGQCQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPCFC 1327
Score = 92.4 bits (228), Expect = 2e-18
Identities = 65/218 (29%), Positives = 86/218 (39%), Gaps = 43/218 (19%)
Query: 345 NCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCV-CKE 403
+C G +C+ C Y R P TC C C C+P TG C C+
Sbjct: 1127 SCPPGYRGPSCQDCDTGY--TRTPSGLYLGTCERCSCHGHSEA----CEPETGACQGCQH 1180
Query: 404 HVQGERCDLCKPGFTG-LTYANPQGCHRCDCNILGSRRDMPCDEESGRCL---------- 452
H +G RC+ C+PG+ G PQ C C C D + + C
Sbjct: 1181 HTEGPRCEQCQPGYYGDAQRGTPQDCQLCPCY-----GDPAAGQAAHTCFLDTDGHPTCD 1235
Query: 453 -CLPNVVGPKCDQCAP-YHWKLASGQGCEP---------CACDPHNSLSPQCNQFTGQCP 501
C P G C++CAP Y+ + GQ C+ C CDP S+S QC+ GQC
Sbjct: 1236 ACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQVPGPIGCNCDPQGSVSSQCDA-AGQCQ 1294
Query: 502 CREGFGGLMCSAAAIRQCPDRTYGDVAT---GCRACDC 536
C+ GL CS C + A+ GC C C
Sbjct: 1295 CKAQVEGLTCS-----HCRPHHFHLSASNPDGCLPCFC 1327
Score = 87.0 bits (214), Expect = 9e-17
Identities = 61/222 (27%), Positives = 83/222 (37%), Gaps = 43/222 (19%)
Query: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
C C +G +CE C + P P G C C+CNGH+ +C DP
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGPYLGT----CSGCNCNGHASSC--DPVY------- 777
Query: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCEC---------------DP 383
G C NC+ +TEG C +C+ +F + + +C C C D
Sbjct: 778 --GHCLNCQHNTEGPQCNKCKAGFFGDAMKATA--TSCRPCPCPYIDASRRFSDTCFLDT 833
Query: 384 DGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMP 443
DG A CD C G RC+ C PG+ G C + I+
Sbjct: 834 DGQ---ATCD------ACAPGYTGRRCESCAPGYEGNPIQPGGKCRPVNQEIVRCDERGS 884
Query: 444 CDEESGRCLCLPNVVGPKCDQCA--PYHWKLASGQGCEPCAC 483
C C NVVG C++CA +H + GC C C
Sbjct: 885 MGTSGEACRCKNNVVGRLCNECADGSFHLSTRNPDGCLKCFC 926
Score = 80.1 bits (196), Expect = 1e-14
Identities = 58/189 (30%), Positives = 78/189 (41%), Gaps = 31/189 (16%)
Query: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERC-APFYNNRPWRPAEG 307
C C+GHA C P V+ C+ CQHNT GP C +C A F+ + A
Sbjct: 764 CNCNGHASSCDP-------------VYGHCLNCQHNTEGPQCNKCKAGFFGD-----AMK 805
Query: 308 QDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNR- 366
A C+ C C + F F + G CD C G+ CE C Y N
Sbjct: 806 ATATSCRPCPCPYIDASRRFSDTCFLDTDGQ--ATCDACAPGYTGRRCESCAPGYEGNPI 863
Query: 367 RPGASIQETCISC-ECDPDGAVPGAPCDPVTGQ-CVCKEHVQGERCDLCKPGFTGLTYAN 424
+PG + CD G++ +G+ C CK +V G C+ C G L+ N
Sbjct: 864 QPGGKCRPVNQEIVRCDERGSMG------TSGEACRCKNNVVGRLCNECADGSFHLSTRN 917
Query: 425 PQGCHRCDC 433
P GC +C C
Sbjct: 918 PDGCLKCFC 926
Score = 75.5 bits (184), Expect = 3e-13
Identities = 53/190 (27%), Positives = 76/190 (40%), Gaps = 36/190 (18%)
Query: 265 ASAGPSTAVQVHDV--CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHS 322
A GPS + +V C C G +C+ CAP Y R G C+ C+CNGHS
Sbjct: 1514 AQPGPSNRPRALEVEECRCPPGYIGLSCQDCAPGYT----RTGSGLYLGHCELCECNGHS 1569
Query: 323 ETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECD 382
+ CH + G C C+ + G+ CE C Y+ + G E C C C
Sbjct: 1570 DLCHPET-----------GACSQCQHNAAGEFCELCAPGYYGDATAGT--PEDCQPCAC- 1615
Query: 383 PDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDM 442
P + + + G RC C+PG+TG Q C +C +G+
Sbjct: 1616 -----PLTNPENMFSRTCESLGAGGYRCTACEPGYTG------QYCEQCGPGYVGNP--- 1661
Query: 443 PCDEESGRCL 452
+ G+CL
Sbjct: 1662 --SVQGGQCL 1669
Score = 70.5 bits (171), Expect = 9e-12
Identities = 51/166 (30%), Positives = 63/166 (37%), Gaps = 37/166 (22%)
Query: 447 ESGRCLCLPNVVGPKCDQCAPYHWKLASG---QGCEPCACDPHNSLSPQCNQFTGQC-PC 502
E C C P +G C CAP + + SG CE C C+ H+ L C+ TG C C
Sbjct: 1526 EVEECRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDL---CHPETGACSQC 1582
Query: 503 REGFGGLMCSAAAIRQCPDRTYGDVATG----CRACDCDFRGTE---GPGCDKASG---R 552
+ G C C YGD G C+ C C E C+ R
Sbjct: 1583 QHNAAGEFCEL-----CAPGYYGDATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYR 1637
Query: 553 C-LCRPGLTGPRCDQCQRGY--------------CNRYPVCVACHP 583
C C PG TG C+QC GY N+ P+ V HP
Sbjct: 1638 CTACEPGYTGQYCEQCGPGYVGNPSVQGGQCLPETNQAPLVVEVHP 1683
Score = 62.8 bits (151), Expect = 2e-09
Identities = 42/122 (34%), Positives = 50/122 (40%), Gaps = 30/122 (24%)
Query: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
C C+GH+D C P+ GA + CQHN AG CE CAP Y + A
Sbjct: 1563 CECNGHSDLCHPETGACS------------QCQHNAAGEFCELCAPGY----YGDATAGT 1606
Query: 310 AHECQRCDC------NGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYF 363
+CQ C C N S TC S GA G C C G+ CE+C Y
Sbjct: 1607 PEDCQPCACPLTNPENMFSRTCE--------SLGAGGYRCTACEPGYTGQYCEQCGPGYV 1658
Query: 364 RN 365
N
Sbjct: 1659 GN 1660
Score = 62.4 bits (150), Expect = 2e-09
Identities = 50/169 (29%), Positives = 64/169 (37%), Gaps = 43/169 (25%)
Query: 432 DCNILGSRRDMPCDEESGR--------CLCLPNVVGPKCDQCAPYHWKLASG---QGCEP 480
+ + G D+ EE+G+ C C P GP C C + + SG CE
Sbjct: 1099 ESRVSGISMDVAVPEETGQDPALEVEQCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCER 1158
Query: 481 CACDPHNSLSPQCNQFTGQCP-CREGFGGLMCSAAAIRQCPDRTYGDVATG----CRACD 535
C+C H S C TG C C+ G C QC YGD G C+ C
Sbjct: 1159 CSCHGH---SEACEPETGACQGCQHHTEGPRC-----EQCQPGYYGDAQRGTPQDCQLCP 1210
Query: 536 C------------DFRGTEG-PGCDKASGRCLCRPGLTGPRCDQCQRGY 571
C F T+G P CD C PG +G C++C GY
Sbjct: 1211 CYGDPAAGQAAHTCFLDTDGHPTCD------ACSPGHSGRHCERCAPGY 1253
Score = 61.6 bits (148), Expect = 4e-09
Identities = 63/233 (27%), Positives = 87/233 (37%), Gaps = 42/233 (18%)
Query: 398 QCVCKEHVQGERCDLCKPGFTGLTYANPQG-CHRCDCNILGSRRDMPCDEESGRCL-CLP 455
+C C G C+ C FT + G C C+CN S CD G CL C
Sbjct: 730 ECRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCNGHASS----CDPVYGHCLNCQH 785
Query: 456 NVVGPKCDQCAPYHW---KLASGQGCEPCAC---DPHNSLSPQCNQFT-GQCPC---REG 505
N GP+C++C + A+ C PC C D S C T GQ C G
Sbjct: 786 NTEGPQCNKCKAGFFGDAMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPG 845
Query: 506 FGGLMCSAAAIRQCPDRTYGDVATG--CRACD-----CDFRGTEGPGCDKASGRCLCRPG 558
+ G C + A P + G CR + CD RG+ G + C C+
Sbjct: 846 YTGRRCESCA----PGYEGNPIQPGGKCRPVNQEIVRCDERGSMGTSGEA----CRCKNN 897
Query: 559 LTGPRCDQCQRGYCNRYPVCVACHPCFQTYDADLREQALRFGRLRNATASLWS 611
+ G C++C G + T + D + G R+ T+S WS
Sbjct: 898 VVGRLCNECADGSFH-----------LSTRNPDGCLKCFCMGVSRHCTSSSWS 939
Score = 40.4 bits (93), Expect = 0.010
Identities = 26/89 (29%), Positives = 32/89 (35%), Gaps = 20/89 (22%)
Query: 480 PCACDP--HNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCD 537
PC P H + ++ QC CR+GF G +C C
Sbjct: 4107 PCERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCEH------------------EENPCQ 4148
Query: 538 FRGTEGPGCDKASGRCLCRPGLTGPRCDQ 566
R G RCLC PG +GPRC Q
Sbjct: 4149 LREPCLHGGTCQGTRCLCLPGFSGPRCQQ 4177
Score = 33.9 bits (76), Expect = 0.93
Identities = 26/90 (28%), Positives = 37/90 (41%), Gaps = 20/90 (22%)
Query: 378 SCECDPDGAVPGAPCDPVTG---QCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCN 434
S C+ GA C P QC+C++ +G+ C+ NP C +
Sbjct: 4105 SSPCERQPCQHGATCMPAGEYEFQCLCRDGFKGDLCE---------HEENP--CQLREPC 4153
Query: 435 ILGSRRDMPCDEESGRCLCLPNVVGPKCDQ 464
+ G C + RCLCLP GP+C Q
Sbjct: 4154 LHGGT----C--QGTRCLCLPGFSGPRCQQ 4177
Score = 31.2 bits (69), Expect = 6.1
Identities = 20/68 (29%), Positives = 28/68 (41%), Gaps = 10/68 (14%)
Query: 506 FGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCD 565
F L +A I CP CR C G + + +S C+C G TG RC+
Sbjct: 3832 FHDLNLTAHGISHCPT---------CRDRPCQ-NGGQCHDSESSSYVCVCPAGFTGSRCE 3881
Query: 566 QCQRGYCN 573
Q +C+
Sbjct: 3882 HSQALHCH 3889
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 116 bits (290), Expect = 1e-25
Identities = 98/325 (30%), Positives = 123/325 (37%), Gaps = 64/325 (19%)
Query: 274 QVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQ-------RCD--------- 317
+++ C+C G C P PW G + ECQ CD
Sbjct: 621 RLYGACLCDPGLYGRFCHLTCP-----PWAFGPGC-SEECQCVQPHTQSCDKRDGSCSCK 674
Query: 318 -------CNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGA 370
C E +F P + A G CD+ G+ +RC F+ G
Sbjct: 675 AGFRGERCQAECELGYFGPGCWQACTCPVGVACDS----VSGECGKRCPAG-FQGEDCGQ 729
Query: 371 SIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDL-CKPGFTGLTYANPQGCH 429
C + GAPC VTGQC C GE C+ C G GL GC
Sbjct: 730 ECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGL------GCQ 783
Query: 430 R-CDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNS 488
C +R CD E+G CLCLP VG +C P W S Q CA D H
Sbjct: 784 EICPACQHAAR----CDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGH-- 837
Query: 489 LSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPG-CD 547
C+ TG C C G+ G C R C +G + C+C + G G CD
Sbjct: 838 ----CHPATGHCSCAPGWTGFSCQ----RACDTGHWGPDCS--HPCNC----SAGHGSCD 883
Query: 548 KASGRCLCRPGLTGPRCD-QCQRGY 571
SG CLC G GPRC+ QC +G+
Sbjct: 884 AISGLCLCEAGYVGPRCEQQCPQGH 908
Score = 114 bits (286), Expect = 4e-25
Identities = 107/394 (27%), Positives = 141/394 (35%), Gaps = 94/394 (23%)
Query: 256 ADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHEC-Q 314
A RC+ PGA+ T C C G CE+ P G +C Q
Sbjct: 1129 AQRCSCPPGAACHHVTGA-----CRCPPGFTGSGCEQACP----------PGSFGEDCAQ 1173
Query: 315 RCDCNGHSETCHFDPAVFAASQGAYGGVCDN-CRDHTEGKNCER---------CQLHYFR 364
C C G + CH + + G +G C C G CE+ C
Sbjct: 1174 MCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGA 1233
Query: 365 NRRP----GASIQETCISCECDPD-----GAVPGAPCDPVTGQCVCKEHVQGERCDL--- 412
R P G TC P+ G GA CDPVTG C+C G RC+
Sbjct: 1234 CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCP 1293
Query: 413 ----------------------------CKPGFTG--LTYANPQGCHRCDCNILGS-RRD 441
C G+TG A P G + C++ S +
Sbjct: 1294 QNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNN 1353
Query: 442 MPCDEESGRCLCLPNVVGPKCDQCAP--YHWKLASGQGCEPCACDPHNSLSPQCNQFTGQ 499
C+ +G C C P G C+ P +H G GC+ H + C+ +G+
Sbjct: 1354 STCEPATGTCRCGPGFYGQACEHPCPPGFH-----GAGCQGLCWCQHGA---PCDPISGR 1405
Query: 500 CPCREGFGGLMCSAAAIRQCPDRTYGDVATGC-RACDCDFRGTEGPGCDKASGRCLCRPG 558
C C GF G C R C ++G+ GC + CDCD G CD +G CLC PG
Sbjct: 1406 CLCPAGFHGHFCE----RGCEPGSFGE---GCHQRCDCD----GGAPCDPVTGLCLCPPG 1454
Query: 559 LTGPRCD-QCQRGYCNRYPVCVACHPCFQTYDAD 591
+G C+ C+RG P C C D D
Sbjct: 1455 RSGATCNLDCRRGQFG--PSCTLHCDCGGGADCD 1486
Score = 107 bits (266), Expect = 9e-23
Identities = 94/335 (28%), Positives = 121/335 (36%), Gaps = 73/335 (21%)
Query: 259 CAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHEC-QRCD 317
C+ SAG + + +C+C+ GP CE+ P +G C QRC
Sbjct: 869 CSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCP----------QGHFGPGCEQRCQ 918
Query: 318 CNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCI 377
C H C G G C++ C +F G + C
Sbjct: 919 CQ-HGAACDHVSGACTCPAGWRGTFCEHA-----------CPAGFF-----GLDCRSAC- 960
Query: 378 SCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILG 437
GA CD V G C+C +G RC P TY H C
Sbjct: 961 -------NCTAGAACDAVNGSCLCPAGRRGPRCAETCPAH---TYG-----HNCS-QACA 1004
Query: 438 SRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGC-EPCACDPHNSLSPQCNQF 496
CD G+C C P +GP C Q P G C C C + C+
Sbjct: 1005 CFNGASCDPVHGQCHCAPGWMGPSCLQACPAG---LYGDNCRHSCLCQNGGT----CDPV 1057
Query: 497 TGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCR-ACDCDFRGTEGPGCDKASGRCLC 555
+G C C EG+ GL C ++C R DV GCR + C G CD +GRCLC
Sbjct: 1058 SGHCACPEGWAGLACE----KECLPR---DVRAGCRHSGGC----LNGGLCDPHTGRCLC 1106
Query: 556 RPGLTGPRCDQ-CQRGY----CNRYPVC---VACH 582
G TG +C C RG+ C + C ACH
Sbjct: 1107 PAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACH 1141
Score = 106 bits (265), Expect = 1e-22
Identities = 98/332 (29%), Positives = 119/332 (35%), Gaps = 70/332 (21%)
Query: 266 SAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQR-CDCNGHSET 324
S G + V C C G +CE P EG+ CQ C H+
Sbjct: 745 SCGGAPCHGVTGQCRCPPGRTGEDCEADCP----------EGRWGLGCQEICPACQHAAR 794
Query: 325 CHFDPAVFAASQGAYGGVC-DNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDP 383
C + G G C D C G +C+ C C
Sbjct: 795 CDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQT--------------------RCSCAN 834
Query: 384 DGAVPGAPCDPVTGQCVCKEHVQGERCD-LCKPGFTGLTYANPQGCHRCDCNILGSRRDM 442
DG C P TG C C G C C G G P H C+C S
Sbjct: 835 DGH-----CHPATGHCSCAPGWTGFSCQRACDTGHWG-----PDCSHPCNC----SAGHG 880
Query: 443 PCDEESGRCLCLPNVVGPKCDQ-CAPYHWKLASGQGCEP-CACDPHNSLSPQCNQFTGQC 500
CD SG CLC VGP+C+Q C H+ G GCE C C H + C+ +G C
Sbjct: 881 SCDAISGLCLCEAGYVGPRCEQQCPQGHF----GPGCEQRCQCQ-HGAA---CDHVSGAC 932
Query: 501 PCREGFGGLMCSAAAIRQCPDRTYGDVATGCR-ACDCDFRGTEGPGCDKASGRCLCRPGL 559
C G+ G C A CP +G CR AC+C T G CD +G CLC G
Sbjct: 933 TCPAGWRGTFCEHA----CPAGFFG---LDCRSACNC----TAGAACDAVNGSCLCPAGR 981
Query: 560 TGPRCDQCQRGYCNRYPVCVACHPCFQTYDAD 591
GPRC + + + AC CF D
Sbjct: 982 RGPRCAETCPAHTYGHNCSQAC-ACFNGASCD 1012
Score = 105 bits (262), Expect = 3e-22
Identities = 105/394 (26%), Positives = 135/394 (34%), Gaps = 114/394 (28%)
Query: 246 LQGSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPA 305
+ GSC C P GP A C +T G NC + +N P
Sbjct: 971 VNGSCLC----------PAGRRGPRCAE------TCPAHTYGHNCSQACACFNGASCDPV 1014
Query: 306 EGQDAHECQRCDCNGHSETCHFDPA------VFAASQGAYGGVCDNCRDHTEGKNCERCQ 359
GQ CH P + A G YG DNCR +N C
Sbjct: 1015 HGQ----------------CHCAPGWMGPSCLQACPAGLYG---DNCRHSCLCQNGGTCD 1055
Query: 360 LHYFRNRRP----GASIQETCISCEC-----DPDGAVPGAPCDPVTGQCVCKEHVQGERC 410
P G + ++ C+ + G + G CDP TG+C+C G++C
Sbjct: 1056 PVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKC 1115
Query: 411 DL-CKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYH 469
C G+ G A RC C C +G C C P G C+Q P
Sbjct: 1116 QSPCLRGWFGEACAQ-----RCSCP-----PGAACHHVTGACRCPPGFTGSGCEQACPPG 1165
Query: 470 WKLASGQGC-EPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYG--- 525
+ G+ C + C C N P C+ TG C C G+ G C ++CP YG
Sbjct: 1166 ---SFGEDCAQMCQCPGEN---PACHPATGTCSCAAGYHGPSCQ----QRCPPGRYGPGC 1215
Query: 526 ------------DVATGCRACDCDFRGTE----------------------GPGCDKASG 551
D ATG C F GT+ G CD +G
Sbjct: 1216 EQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTG 1275
Query: 552 RCLCRPGLTGPRCDQCQRGYCNRYPVCVAC-HPC 584
CLC PG G R C+RG C + V C H C
Sbjct: 1276 TCLCPPGRAGVR---CERG-CPQNRFGVGCEHTC 1305
Score = 95.1 bits (235), Expect = 3e-19
Identities = 91/312 (29%), Positives = 114/312 (36%), Gaps = 76/312 (24%)
Query: 259 CAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQR-CD 317
C GA+ P T C+C AG CER P + + C+ C
Sbjct: 1262 CGCGQGAACDPVTGT-----CLCPPGRAGVRCERGCP----------QNRFGVGCEHTCS 1306
Query: 318 CNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCE-RCQLHYFRNRRPGASIQETC 376
C + CH A G C +C G++CE C PG
Sbjct: 1307 CR-NGGLCH-----------ASNGSC-SCGLGWTGRHCELACP--------PGRYGAACH 1345
Query: 377 ISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDL-CKPGFTGLTYANPQGCHRCDCNI 435
+ C C + C+P TG C C G+ C+ C PGF G A QG C
Sbjct: 1346 LECSCHNNST-----CEPATGTCRCGPGFYGQACEHPCPPGFHG---AGCQGLCWC---- 1393
Query: 436 LGSRRDMPCDEESGRCLCLPNVVGPKCDQ-CAPYHWKLASGQGC-EPCACDPHNSLSPQC 493
+ PCD SGRCLC G C++ C P + G+GC + C CD C
Sbjct: 1394 ---QHGAPCDPISGRCLCPAGFHGHFCERGCEPGSF----GEGCHQRCDCDG----GAPC 1442
Query: 494 NQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRA-CDCDFRGTEGPGCDKASGR 552
+ TG C C G G C+ R G C CDC G CD SG+
Sbjct: 1443 DPVTGLCLCPPGRSGATCNLDCRR-------GQFGPSCTLHCDCG----GGADCDPVSGQ 1491
Query: 553 CLCRPGLTGPRC 564
C C G GP C
Sbjct: 1492 CHCVDGYMGPTC 1503
Score = 90.1 bits (222), Expect = 1e-17
Identities = 83/266 (31%), Positives = 100/266 (37%), Gaps = 64/266 (24%)
Query: 311 HECQ-RCDCNGHSETCHFDPAVFAASQGAYGGVC-DNCRDHTEGKNCERCQLHYFRNRRP 368
H+C CD + TC +G G +C + C T GKNC
Sbjct: 518 HDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCS------------ 565
Query: 369 GASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERC-DLCKPGFTGLTYANPQG 427
SC C G CD VTG C C V G C D C G+ G +
Sbjct: 566 --------FSCSCQNGGT-----CDSVTGACRCPPGVSGTNCEDGCPKGYYG------KH 606
Query: 428 CH-RCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCD-QCAPYHWKLASGQGC-EPCAC- 483
C +C+C G C G CLC P + G C C P+ A G GC E C C
Sbjct: 607 CRKKCNCANRGR-----CHRLYGACLCDPGLYGRFCHLTCPPW----AFGPGCSEECQCV 657
Query: 484 DPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGC-RACDCDFRGTE 542
PH + C++ G C C+ GF G C A +C G GC +AC C
Sbjct: 658 QPH---TQSCDKRDGSCSCKAGFRGERCQA----EC---ELGYFGPGCWQACTCPV---- 703
Query: 543 GPGCDKASGRC--LCRPGLTGPRCDQ 566
G CD SG C C G G C Q
Sbjct: 704 GVACDSVSGECGKRCPAGFQGEDCGQ 729
Score = 64.7 bits (156), Expect = 5e-10
Identities = 42/124 (33%), Positives = 59/124 (47%), Gaps = 17/124 (13%)
Query: 500 CPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGL 559
C C EG+ GL+C+ CP T+G + +C C GT CD +G C C PG+
Sbjct: 540 CDCPEGWTGLICNET----CPPDTFGKNCSF--SCSCQNGGT----CDSVTGACRCPPGV 589
Query: 560 TGPRC-DQCQRGY----CNRYPVCVACHPCFQTYDADLREQALRFGRLRNATASLWS-GP 613
+G C D C +GY C + C C + Y A L + L +GR + T W+ GP
Sbjct: 590 SGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGL-YGRFCHLTCPPWAFGP 648
Query: 614 GLED 617
G +
Sbjct: 649 GCSE 652
Score = 46.2 bits (108), Expect = 2e-04
Identities = 62/244 (25%), Positives = 85/244 (34%), Gaps = 47/244 (19%)
Query: 373 QETCISCECDPDGAVPGAPCDPVTGQ-CVCKEHVQGERC----DLCKPGFTGLTY--ANP 425
+E C+S EC G C P + Q C C QG RC D C+ G + N
Sbjct: 120 EEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNT 179
Query: 426 QGCHRCDCN-----ILGSRRDM---PCDEESGRCL--CLPNVVGPKCDQCAPYHWKLASG 475
G + C+C SR + C +G C C+ + QC P G
Sbjct: 180 PGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDG 239
Query: 476 QGC---EPCACDPHNSLSPQCNQFTG--QCPCREGF----GGLMCS-----AAAIRQCPD 521
+ C PCA + + S +C G +C C G+ G C AA + QC
Sbjct: 240 RHCVRRSPCA-NRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAH 298
Query: 522 RTYGDVATGCRACDCDFR-GTEG-----------PGCDKASGRCL--CRPGLTGPRCDQC 567
+ C + G +G C+ +G C C GP C C
Sbjct: 299 GCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLC-TC 357
Query: 568 QRGY 571
RGY
Sbjct: 358 PRGY 361
>gi|122937440 multiple EGF-like-domains 9 [Homo sapiens]
Length = 639
Score = 114 bits (285), Expect = 5e-25
Identities = 72/211 (34%), Positives = 99/211 (46%), Gaps = 22/211 (10%)
Query: 379 CECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGS 438
C C G++ C+ TGQC C+ QG C+ CK GF L Y + C CDC+ G+
Sbjct: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFY-LNYTSGL-CQPCDCSPHGA 298
Query: 439 RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTG 498
+PC+ SG+C C V+G CD+C ++ S GC PC C N+ S C+ TG
Sbjct: 299 -LSIPCN-SSGKCQCKVGVIGSICDRCQDGYYGF-SKNGCLPCQC---NNRSASCDALTG 352
Query: 499 QC-PCREGFGGLMCSAA--AIRQCPDRTYGDVATGCRAC----DCDFRGTE-GPGCDKAS 550
C C+E G C Q PD T + C A C + +E P CD+
Sbjct: 353 ACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQ-- 410
Query: 551 GRCLCRPGLTGPRCDQCQRGYCNRYPVCVAC 581
C+ G GP C++C+ GY N +C C
Sbjct: 411 ----CKDGYIGPNCNKCENGYYNFDSICRKC 437
Score = 101 bits (252), Expect = 4e-21
Identities = 53/189 (28%), Positives = 87/189 (46%), Gaps = 10/189 (5%)
Query: 397 GQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPN 456
G+ C+ +++ + L +P + + C+C+++GS C++ +G+C C P
Sbjct: 207 GKYACESNLKSKYLPLTQPVMNLRVSEAVKTEYVCNCSVVGSLNVNRCNQTTGQCECRPG 266
Query: 457 VVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAI 516
G C+ C + + C+PC C PH +LS CN +G+C C+ G G +C
Sbjct: 267 YQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALSIPCNS-SGKCQCKVGVIGSICD---- 321
Query: 517 RQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCL-CRPGLTGPRCDQCQRGYCNRY 575
+C D YG GC C C+ R CD +G CL C+ G C++C+ G+
Sbjct: 322 -RCQDGYYGFSKNGCLPCQCNNRSAS---CDALTGACLNCQENSKGNHCEECKEGFYQSP 377
Query: 576 PVCVACHPC 584
C C
Sbjct: 378 DATKECLRC 386
Score = 101 bits (252), Expect = 4e-21
Identities = 75/249 (30%), Positives = 107/249 (42%), Gaps = 47/249 (18%)
Query: 341 GVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCV 400
G C+ CR +G +CE C+ ++ N G C C+C P GA+ PC+ +G+C
Sbjct: 259 GQCE-CRPGYQGLHCETCKEGFYLNYTSG-----LCQPCDCSPHGAL-SIPCNS-SGKCQ 310
Query: 401 CKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCL-CLPNVVG 459
CK V G CD C+ G+ G + GC C CN R CD +G CL C N G
Sbjct: 311 CKVGVIGSICDRCQDGYYGF---SKNGCLPCQCN----NRSASCDALTGACLNCQENSKG 363
Query: 460 PKCDQCAP-YHWKLASGQGCEPCACDPHNS----------LSPQCNQFTGQCPCREGFGG 508
C++C ++ + + C C C S L P+C+Q C++G+ G
Sbjct: 364 NHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQ------CKDGYIG 417
Query: 509 LMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPG-----CDKASGRCL-CRPGLTGP 562
C+ + Y + + CR C C G P C SG C+ C TG
Sbjct: 418 PNCNKC------ENGYYNFDSICRKCQC--HGHVDPVKTPKICKPESGECINCLHNTTGF 469
Query: 563 RCDQCQRGY 571
C+ C GY
Sbjct: 470 WCENCLEGY 478
Score = 77.8 bits (190), Expect = 6e-14
Identities = 55/198 (27%), Positives = 80/198 (40%), Gaps = 43/198 (21%)
Query: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGA 338
C C+ G C+RC Y G + C C CN S +C A
Sbjct: 309 CQCKVGVIGSICDRCQDGYY--------GFSKNGCLPCQCNNRSASCD-----------A 349
Query: 339 YGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQ 398
G C NC+++++G +CE C+ ++++ P A+ + C+ C C AV TG
Sbjct: 350 LTGACLNCQENSKGNHCEECKEGFYQS--PDAT--KECLRCPC---SAVTS------TGS 396
Query: 399 CVCKEHVQGERCDLCKPGFTGLT--------YANPQGCHRCDC--NILGSRRDMPCDEES 448
C K CD CK G+ G Y C +C C ++ + C ES
Sbjct: 397 CSIKSSELEPECDQCKDGYIGPNCNKCENGYYNFDSICRKCQCHGHVDPVKTPKICKPES 456
Query: 449 GRCL-CLPNVVGPKCDQC 465
G C+ CL N G C+ C
Sbjct: 457 GECINCLHNTTGFWCENC 474
Score = 31.2 bits (69), Expect = 6.1
Identities = 19/55 (34%), Positives = 21/55 (38%), Gaps = 20/55 (36%)
Query: 250 CFCHGHADR------CAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFY 297
C CHGH D C P+ G C+ C HNT G CE C Y
Sbjct: 437 CQCHGHVDPVKTPKICKPESGE-------------CINCLHNTTGFWCENCLEGY 478
>gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo
sapiens]
Length = 870
Score = 112 bits (280), Expect = 2e-24
Identities = 114/365 (31%), Positives = 136/365 (37%), Gaps = 88/365 (24%)
Query: 250 CFCHGHADRCAPKPGASAGPST--AVQVHDVCVCQHNTAGPNCE--RCAPFYNNRPWRPA 305
C CH H +C G + + C CQH T P RC P W A
Sbjct: 126 CSCHPHG-QCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEP-----GWWGA 179
Query: 306 EGQDAHECQ---RCDCNGHSETCHFDPAVFAASQGAYGGVCDN---CRDHTEGKNCERCQ 359
+ A C RCD + CH G +G C+N C + RCQ
Sbjct: 180 QCASACYCSATSRCDPQTGACLCH---------AGWWGRSCNNQCACNSSPCEQQSGRCQ 230
Query: 360 LHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERC-DLCKPGFT 418
R R GA C +C C PV G C C+ +G+ C + C GF
Sbjct: 231 C---RERTFGARCDRYC---QCFR------GRCHPVDGTCACEPGYRGKYCREPCPAGFY 278
Query: 419 GLTYANPQGCHRCDCNILGSRRDMPCDEESGRCL-CLPNVVGPKCDQ-CAPYHWKLASGQ 476
GL GC R G + PC GRCL C P G KCDQ CA +
Sbjct: 279 GL------GCRRRCGQCKGQQ---PCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSH 329
Query: 477 GCEPCACDPHNSLSPQCNQFTGQCP-CREGFGGLMCSAAAIRQCPDRTYG-DVATGCRAC 534
C PC D H CN TG+C C G+ G C +C + TYG D A C C
Sbjct: 330 RCPPCR-DGH-----ACNHVTGKCTRCNAGWIGDRCET----KCSNGTYGEDCAFVCADC 379
Query: 535 DCDFRGTEGPG-CDKASGRCLCRPGLTGPRCD----------------QCQRGYCNRYPV 577
G G CD SGRCLC PG+ GP C+ C C+ PV
Sbjct: 380 --------GSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCD--PV 429
Query: 578 CVACH 582
ACH
Sbjct: 430 TGACH 434
Score = 81.3 bits (199), Expect = 5e-15
Identities = 79/289 (27%), Positives = 101/289 (34%), Gaps = 95/289 (32%)
Query: 302 WRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCE-RCQL 360
WR Q EC C G+S TC + G C CR G NC+ +C
Sbjct: 68 WR----QQGDECGIAVCEGNS-TCSENEVCVRP------GEC-RCRHGYFGANCDTKCPR 115
Query: 361 HYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGL 420
++ G +E C C P G C+ VTGQC C G RC+
Sbjct: 116 QFW-----GPDCKELC---SCHPHGQ-----CEDVTGQCTCHARRWGARCE--------- 153
Query: 421 TYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEP 480
H C C + C SG C C P G +C
Sbjct: 154 --------HACQC------QHGTCHPRSGACRCEPGWWGAQC---------------ASA 184
Query: 481 CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRG 540
C C S + +C+ TG C C G+ G C+ QC AC+
Sbjct: 185 CYC----SATSRCDPQTGACLCHAGWWGRSCN----NQC-------------ACNSS--- 220
Query: 541 TEGPGCDKASGRCLCRPGLTGPRCD---QCQRGYCNRYPVCVACHPCFQ 586
C++ SGRC CR G RCD QC RG C+ AC P ++
Sbjct: 221 ----PCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYR 265
Score = 68.6 bits (166), Expect = 3e-11
Identities = 82/301 (27%), Positives = 109/301 (36%), Gaps = 73/301 (24%)
Query: 249 SCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCE-RCAPFYNNRPWRPAEG 307
+C+C RC P+ GA C+C G +C +CA N+ P G
Sbjct: 184 ACYCSA-TSRCDPQTGA-------------CLCHAGWWGRSCNNQCA--CNSSPCEQQSG 227
Query: 308 QDAHECQ--------RCD--CNGHSETCHFDPAVFAASQGAYGGVC-DNCRDHTEGKNCE 356
+ CQ RCD C CH A G G C + C G C
Sbjct: 228 R----CQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCR 283
Query: 357 RCQLHYFRNRRPGASIQETCISCE-------CDPDGAV---------------PGAPCDP 394
R + + ++P + C++CE CD A G C+
Sbjct: 284 R-RCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNH 342
Query: 395 VTGQCV-CKEHVQGERCDL-CKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCL 452
VTG+C C G+RC+ C G TY DC GS CD +SGRCL
Sbjct: 343 VTGKCTRCNAGWIGDRCETKCSNG----TYGEDCAFVCADC---GSGH---CDFQSGRCL 392
Query: 453 CLPNVVGPKCDQCAP---YHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGL 509
C P V GP C+ P + A C CDP ++ C+ T Q G G L
Sbjct: 393 CSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDP---VTGACHLETNQRKGVMGAGAL 449
Query: 510 M 510
+
Sbjct: 450 L 450
Score = 51.2 bits (121), Expect = 6e-06
Identities = 41/142 (28%), Positives = 60/142 (42%), Gaps = 24/142 (16%)
Query: 449 GRCLC-LPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQ--CNQFTGQCPCREG 505
GR +C P P C CA + + G C C+ +++ S C + G+C CR G
Sbjct: 50 GRNVCRAPGSQVPTC--CAGWRQQ---GDECGIAVCEGNSTCSENEVCVR-PGECRCRHG 103
Query: 506 FGGLMCSAAAIRQCPDRTYGDVATGCR-ACDCDFRGTEGPGCDKASGRCLCRPGLTGPRC 564
+ G C +CP + +G C+ C C G C+ +G+C C G RC
Sbjct: 104 YFGANCDT----KCPRQFWG---PDCKELCSCHPHGQ----CEDVTGQCTCHARRWGARC 152
Query: 565 D---QCQRGYCNRYPVCVACHP 583
+ QCQ G C+ C P
Sbjct: 153 EHACQCQHGTCHPRSGACRCEP 174
>gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo
sapiens]
Length = 865
Score = 112 bits (280), Expect = 2e-24
Identities = 114/365 (31%), Positives = 136/365 (37%), Gaps = 88/365 (24%)
Query: 250 CFCHGHADRCAPKPGASAGPST--AVQVHDVCVCQHNTAGPNCE--RCAPFYNNRPWRPA 305
C CH H +C G + + C CQH T P RC P W A
Sbjct: 126 CSCHPHG-QCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEP-----GWWGA 179
Query: 306 EGQDAHECQ---RCDCNGHSETCHFDPAVFAASQGAYGGVCDN---CRDHTEGKNCERCQ 359
+ A C RCD + CH G +G C+N C + RCQ
Sbjct: 180 QCASACYCSATSRCDPQTGACLCH---------AGWWGRSCNNQCACNSSPCEQQSGRCQ 230
Query: 360 LHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERC-DLCKPGFT 418
R R GA C +C C PV G C C+ +G+ C + C GF
Sbjct: 231 C---RERTFGARCDRYC---QCFR------GRCHPVDGTCACEPGYRGKYCREPCPAGFY 278
Query: 419 GLTYANPQGCHRCDCNILGSRRDMPCDEESGRCL-CLPNVVGPKCDQ-CAPYHWKLASGQ 476
GL GC R G + PC GRCL C P G KCDQ CA +
Sbjct: 279 GL------GCRRRCGQCKGQQ---PCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSH 329
Query: 477 GCEPCACDPHNSLSPQCNQFTGQCP-CREGFGGLMCSAAAIRQCPDRTYG-DVATGCRAC 534
C PC D H CN TG+C C G+ G C +C + TYG D A C C
Sbjct: 330 RCPPCR-DGH-----ACNHVTGKCTRCNAGWIGDRCET----KCSNGTYGEDCAFVCADC 379
Query: 535 DCDFRGTEGPG-CDKASGRCLCRPGLTGPRCD----------------QCQRGYCNRYPV 577
G G CD SGRCLC PG+ GP C+ C C+ PV
Sbjct: 380 --------GSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCD--PV 429
Query: 578 CVACH 582
ACH
Sbjct: 430 TGACH 434
Score = 81.3 bits (199), Expect = 5e-15
Identities = 79/289 (27%), Positives = 101/289 (34%), Gaps = 95/289 (32%)
Query: 302 WRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCE-RCQL 360
WR Q EC C G+S TC + G C CR G NC+ +C
Sbjct: 68 WR----QQGDECGIAVCEGNS-TCSENEVCVRP------GEC-RCRHGYFGANCDTKCPR 115
Query: 361 HYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGL 420
++ G +E C C P G C+ VTGQC C G RC+
Sbjct: 116 QFW-----GPDCKELC---SCHPHGQ-----CEDVTGQCTCHARRWGARCE--------- 153
Query: 421 TYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEP 480
H C C + C SG C C P G +C
Sbjct: 154 --------HACQC------QHGTCHPRSGACRCEPGWWGAQC---------------ASA 184
Query: 481 CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRG 540
C C S + +C+ TG C C G+ G C+ QC AC+
Sbjct: 185 CYC----SATSRCDPQTGACLCHAGWWGRSCN----NQC-------------ACNSS--- 220
Query: 541 TEGPGCDKASGRCLCRPGLTGPRCD---QCQRGYCNRYPVCVACHPCFQ 586
C++ SGRC CR G RCD QC RG C+ AC P ++
Sbjct: 221 ----PCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYR 265
Score = 68.6 bits (166), Expect = 3e-11
Identities = 82/301 (27%), Positives = 109/301 (36%), Gaps = 73/301 (24%)
Query: 249 SCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCE-RCAPFYNNRPWRPAEG 307
+C+C RC P+ GA C+C G +C +CA N+ P G
Sbjct: 184 ACYCSA-TSRCDPQTGA-------------CLCHAGWWGRSCNNQCA--CNSSPCEQQSG 227
Query: 308 QDAHECQ--------RCD--CNGHSETCHFDPAVFAASQGAYGGVC-DNCRDHTEGKNCE 356
+ CQ RCD C CH A G G C + C G C
Sbjct: 228 R----CQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCR 283
Query: 357 RCQLHYFRNRRPGASIQETCISCE-------CDPDGAV---------------PGAPCDP 394
R + + ++P + C++CE CD A G C+
Sbjct: 284 R-RCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNH 342
Query: 395 VTGQCV-CKEHVQGERCDL-CKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCL 452
VTG+C C G+RC+ C G TY DC GS CD +SGRCL
Sbjct: 343 VTGKCTRCNAGWIGDRCETKCSNG----TYGEDCAFVCADC---GSGH---CDFQSGRCL 392
Query: 453 CLPNVVGPKCDQCAP---YHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGL 509
C P V GP C+ P + A C CDP ++ C+ T Q G G L
Sbjct: 393 CSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDP---VTGACHLETNQRKGVMGAGAL 449
Query: 510 M 510
+
Sbjct: 450 L 450
Score = 51.2 bits (121), Expect = 6e-06
Identities = 41/142 (28%), Positives = 60/142 (42%), Gaps = 24/142 (16%)
Query: 449 GRCLC-LPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQ--CNQFTGQCPCREG 505
GR +C P P C CA + + G C C+ +++ S C + G+C CR G
Sbjct: 50 GRNVCRAPGSQVPTC--CAGWRQQ---GDECGIAVCEGNSTCSENEVCVR-PGECRCRHG 103
Query: 506 FGGLMCSAAAIRQCPDRTYGDVATGCR-ACDCDFRGTEGPGCDKASGRCLCRPGLTGPRC 564
+ G C +CP + +G C+ C C G C+ +G+C C G RC
Sbjct: 104 YFGANCDT----KCPRQFWG---PDCKELCSCHPHGQ----CEDVTGQCTCHARRWGARC 152
Query: 565 D---QCQRGYCNRYPVCVACHP 583
+ QCQ G C+ C P
Sbjct: 153 EHACQCQHGTCHPRSGACRCEP 174
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 109 bits (272), Expect = 2e-23
Identities = 107/346 (30%), Positives = 128/346 (36%), Gaps = 90/346 (26%)
Query: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNC-ERCAPFYNNRPWRPAEGQ 308
C C G+ C PK G VC C PNC + C P Y + PA
Sbjct: 148 CSC-GNNSSCDPKSG-------------VCSCPSGLQPPNCLQPCTPGY----YGPA--- 186
Query: 309 DAHECQ-RCDCNGHSETCHFDPAVFAASQGAYGGVCD-NCRDHTEGKNCERCQLHYFRNR 366
CQ RC C H C G CD +C T G C H +N
Sbjct: 187 ----CQFRCQC--HGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCP--STHSCQN- 237
Query: 367 RPGASIQETCISCECDPD--GAVPGAPC---------------------DPVTGQCVCKE 403
G Q SC C P G + PC D TGQC C
Sbjct: 238 --GGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAP 295
Query: 404 HVQGERC-DLCKPGFTGLTYANPQGC-HRCDCNILGSRRDMPCDEESGRCLCLPNVVGPK 461
G+RC + C G G Q C CDC D C +G CLC G +
Sbjct: 296 GYTGDRCREECPVGRFG------QDCAETCDC-----APDARCFPANGACLCEHGFTGDR 344
Query: 462 C-DQCAPYHWKLASGQGCE-PCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQC 519
C D+ P + G C+ PC CD +SLS C+ G+C C G+ GL C+ + C
Sbjct: 345 CTDRLCPDGFY---GLSCQAPCTCDREHSLS--CHPMNGECSCLPGWAGLHCNES----C 395
Query: 520 PDRTYGDVATGCRA-CDCDFRGTEGPGCDKASGRCLCRPGLTGPRC 564
P T+G GC+ C C G C SG C C PG TGP C
Sbjct: 396 PQDTHGP---GCQEHCLC----LHGGVCQATSGLCQCAPGYTGPHC 434
Score = 106 bits (265), Expect = 1e-22
Identities = 105/368 (28%), Positives = 136/368 (36%), Gaps = 91/368 (24%)
Query: 256 ADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNC-ERCAPFYNNRPWRPAEGQDAHECQ 314
A+ C P A P+ C+C+H G C +R P +G CQ
Sbjct: 316 AETCDCAPDARCFPANGA-----CLCEHGFTGDRCTDRLCP----------DGFYGLSCQ 360
Query: 315 R-CDCNG-HSETCHFDPAVFAASQGAYGGVC-DNCRDHTEGKNC-ERCQ-LHYFRNRRPG 369
C C+ HS +CH + G G C ++C T G C E C LH G
Sbjct: 361 APCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLH-------G 413
Query: 370 ASIQETCISCECDPDGAVP-----------------------GAPCDPVTGQCVCKEHVQ 406
Q T C+C P P C P+ G+CVCKE Q
Sbjct: 414 GVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQ 473
Query: 407 GERCDL-CKPGFTGLTYANPQGCHR-CDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQ 464
C + C PG G + C+ C C + C ++G C C P G C
Sbjct: 474 RGNCSVPCPPGTWGFS------CNASCQC-----AHEAVCSPQTGACTCTPGWHGAHCQL 522
Query: 465 CAPYHWKLASGQGCEP-CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRT 523
P K G+GC C CD S C+ G+C C+ G+ G C + CP+
Sbjct: 523 PCP---KGQFGEGCASRCDCDH----SDGCDPVHGRCQCQAGWMGARCHLS----CPEGL 571
Query: 524 YGDVATGC-RACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQ-CQRG-YCNRYPVCVA 580
+G C C C GT C +G C+C PG GP C + CQ G Y R C
Sbjct: 572 WG---VNCSNTCTCKNGGT----CLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKC 624
Query: 581 -----CHP 583
CHP
Sbjct: 625 ANHSFCHP 632
Score = 97.1 bits (240), Expect = 9e-20
Identities = 91/323 (28%), Positives = 115/323 (35%), Gaps = 88/323 (27%)
Query: 249 SCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
SC C H C+P+ GA C C G +C+ P +GQ
Sbjct: 493 SCQC-AHEAVCSPQTGA-------------CTCTPGWHGAHCQLPCP----------KGQ 528
Query: 309 DAHEC-QRCDCNGHSETCHFDPAVFAASQGAYGGVCD-NCRDHTEGKNCERCQLHYFRNR 366
C RCDC+ HS+ C G G C +C + G NC
Sbjct: 529 FGEGCASRCDCD-HSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSN--------- 578
Query: 367 RPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDL-CKPGFTGLTYANP 425
+C C G C P G CVC +G C C+PG G
Sbjct: 579 -----------TCTCKNGGT-----CLPENGNCVCAPGFRGPSCQRSCQPGRYG------ 616
Query: 426 QGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQ-CAPYHWKLASGQGC-EPCAC 483
+ C C C C +G C CL GP C Q C P HW G+ C + C C
Sbjct: 617 KRCVPCKC-----ANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHW----GENCAQTCQC 667
Query: 484 DPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEG 543
+ PQ G C C G+ G C + CP T+G A + C C G
Sbjct: 668 HHGGTCHPQ----DGSCICPLGWTGHHC----LEGCPLGTFG--ANCSQPCQC------G 711
Query: 544 PG--CDKASGRCLCRPGLTGPRC 564
PG C +G C+C PG +G C
Sbjct: 712 PGEKCHPETGACVCPPGHSGAPC 734
Score = 85.1 bits (209), Expect = 4e-16
Identities = 68/229 (29%), Positives = 90/229 (39%), Gaps = 48/229 (20%)
Query: 380 ECD-PDGAVPGAPCDPVTGQCVCKEHVQGERC-DLCKPGFTGLTYANPQGCHRCDCNILG 437
+CD P + CDP +G C C +Q C C PG+ G P RC C+
Sbjct: 143 QCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYG-----PACQFRCQCH--- 194
Query: 438 SRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSL-------S 490
PCD ++G C C GP CD ++ QG C +S +
Sbjct: 195 ---GAPCDPQTGACFCPAERTGPSCD--------VSCSQGTSGFFCPSTHSCQNGGVFQT 243
Query: 491 PQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKAS 550
PQ G C C G+ G +CS CP+ +G C + R G CD+ +
Sbjct: 244 PQ-----GSCSCPPGWMGTICSLP----CPEGFHGP------NCSQECRCHNGGLCDRFT 288
Query: 551 GRCLCRPGLTGPRC-DQCQRGY----CNRYPVCVACHPCFQTYDADLRE 594
G+C C PG TG RC ++C G C C CF A L E
Sbjct: 289 GQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCE 337
Score = 55.8 bits (133), Expect = 2e-07
Identities = 45/158 (28%), Positives = 62/158 (39%), Gaps = 42/158 (26%)
Query: 429 HRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNS 488
++C C + G R D C E C P + GP+CD +PC+C ++S
Sbjct: 118 NQCQC-VPGWRGD-DCSSE-----CAPGMWGPQCD---------------KPCSCGNNSS 155
Query: 489 LSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFR-GTEGPGCD 547
P+ +G C C G C ++ C YG C FR G CD
Sbjct: 156 CDPK----SGVCSCPSGLQPPNC----LQPCTPGYYGPA--------CQFRCQCHGAPCD 199
Query: 548 KASGRCLCRPGLTGPRCD-QCQRGYCNRYPVCVACHPC 584
+G C C TGP CD C +G + C + H C
Sbjct: 200 PQTGACFCPAERTGPSCDVSCSQGTSGFF--CPSTHSC 235
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.133 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,415,211
Number of Sequences: 37866
Number of extensions: 2392600
Number of successful extensions: 13434
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 123
Number of HSP's successfully gapped in prelim test: 532
Number of HSP's that attempted gapping in prelim test: 8107
Number of HSP's gapped (non-prelim): 2714
length of query: 1172
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1059
effective length of database: 13,968,660
effective search space: 14792810940
effective search space used: 14792810940
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.