Guide to the Human Genome
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Search of human proteins with 189011544

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|189011544 ubiquitously transcribed tetratricopeptide repeat,
X chromosome [Homo sapiens]
         (1401 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189011544 ubiquitously transcribed tetratricopeptide repeat, ...  2871   0.0  
gi|33188431 tetratricopeptide repeat protein isoform 3 [Homo sap...  2344   0.0  
gi|33188427 tetratricopeptide repeat protein isoform 2 [Homo sap...  2160   0.0  
gi|33188429 tetratricopeptide repeat protein isoform 1 [Homo sap...  1660   0.0  
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]        711   0.0  
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]       58   6e-08
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]       58   6e-08
gi|151301154 mucin 6, gastric [Homo sapiens]                           58   6e-08
gi|118402596 cell division cycle protein 23 [Homo sapiens]             54   8e-07
gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens]                     52   3e-06
gi|161016767 mucin 21 [Homo sapiens]                                   52   4e-06
gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens]           51   7e-06
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]         51   9e-06
gi|116805348 trinucleotide repeat containing 6A [Homo sapiens]         51   9e-06
gi|224809432 transmembrane and tetratricopeptide repeat containi...    50   1e-05
gi|167736355 mucin 4 isoform a [Homo sapiens]                          49   3e-05
gi|20143482 melanoma antigen family E, 1 [Homo sapiens]                47   1e-04
gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]    47   2e-04
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        47   2e-04
gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapi...    47   2e-04
gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapi...    47   2e-04
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                        46   2e-04
gi|118766328 transmembrane and tetratricopeptide repeat containi...    46   3e-04
gi|118766330 transmembrane and tetratricopeptide repeat containi...    46   3e-04
gi|161019170 mucin 5AC [Homo sapiens]                                  43   0.002
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            42   0.003
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]            42   0.003
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]            42   0.003
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]            42   0.003
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...    42   0.003

>gi|189011544 ubiquitously transcribed tetratricopeptide repeat, X
            chromosome [Homo sapiens]
          Length = 1401

 Score = 2871 bits (7442), Expect = 0.0
 Identities = 1401/1401 (100%), Positives = 1401/1401 (100%)

Query: 1    MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV 60
            MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV
Sbjct: 1    MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV 60

Query: 61   RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY 120
            RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY
Sbjct: 61   RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY 120

Query: 121  SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN 180
            SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN
Sbjct: 121  SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN 180

Query: 181  TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ 240
            TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ
Sbjct: 181  TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ 240

Query: 241  VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV 300
            VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
Sbjct: 241  VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV 300

Query: 301  QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT 360
            QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
Sbjct: 301  QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT 360

Query: 361  LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE 420
            LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE
Sbjct: 361  LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE 420

Query: 421  EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL 480
            EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL
Sbjct: 421  EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL 480

Query: 481  RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG 540
            RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG
Sbjct: 481  RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG 540

Query: 541  QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG 600
            QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG
Sbjct: 541  QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG 600

Query: 601  SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL 660
            SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL
Sbjct: 601  SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL 660

Query: 661  SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP 720
            SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP
Sbjct: 661  SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP 720

Query: 721  SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL 780
            SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL
Sbjct: 721  SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL 780

Query: 781  SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS 840
            SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS
Sbjct: 781  SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS 840

Query: 841  VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC 900
            VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC
Sbjct: 841  VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC 900

Query: 901  RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC 960
            RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
Sbjct: 901  RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC 960

Query: 961  TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI 1020
            TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
Sbjct: 961  TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI 1020

Query: 1021 WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK 1080
            WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK
Sbjct: 1021 WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK 1080

Query: 1081 TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG 1140
            TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG
Sbjct: 1081 TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG 1140

Query: 1141 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL 1200
            SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL
Sbjct: 1141 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL 1200

Query: 1201 YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK 1260
            YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK
Sbjct: 1201 YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK 1260

Query: 1261 LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWH 1320
            LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWH
Sbjct: 1261 LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWH 1320

Query: 1321 GRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKM 1380
            GRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKM
Sbjct: 1321 GRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKM 1380

Query: 1381 EDLMQVYDQFTLAPPLPSASS 1401
            EDLMQVYDQFTLAPPLPSASS
Sbjct: 1381 EDLMQVYDQFTLAPPLPSASS 1401


>gi|33188431 tetratricopeptide repeat protein isoform 3 [Homo sapiens]
          Length = 1347

 Score = 2344 bits (6075), Expect = 0.0
 Identities = 1166/1400 (83%), Positives = 1232/1400 (88%), Gaps = 53/1400 (3%)

Query: 1    MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV 60
            MKSC VSL TAA A   FGDE KKMA GKAS ESEE S SLT EEREALGG+DSRLFGFV
Sbjct: 1    MKSCAVSLTTAAVA---FGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFV 57

Query: 61   RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY 120
            R HEDGARTK LLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDY KALSAYQRYY
Sbjct: 58   RLHEDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYY 117

Query: 121  SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN 180
            SLQ+DYWKNAAFLYGLGLVYF+YNAF WAIKAFQ+VLYVDPSFCRAKEIHLRLGLMFKVN
Sbjct: 118  SLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVN 177

Query: 181  TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ 240
            TDY+SSLKHFQLAL+DCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENL AQ
Sbjct: 178  TDYKSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQ 237

Query: 241  VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV 300
            VKATVLQQLGWMHH +DL+GDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
Sbjct: 238  VKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV 297

Query: 301  QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT 360
            QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
Sbjct: 298  QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT 357

Query: 361  LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE 420
            LYESCNQPQDAIKCYLNA RSK CSNTS LAARIK+LQ                      
Sbjct: 358  LYESCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQ---------------------- 395

Query: 421  EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL 480
                                   N SDNW+GG ++SH PVQQ  +S CLTPQKLQHLEQL
Sbjct: 396  -----------------------NGSDNWNGGQSLSHHPVQQ-VYSLCLTPQKLQHLEQL 431

Query: 481  RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG 540
            RANR+NLNPAQK  LEQLESQFVLMQQ  MR   VAQVR+TGI NG   DSSLPTNSVS 
Sbjct: 432  RANRDNLNPAQKHQLEQLESQFVLMQQ--MRHKEVAQVRTTGIHNGAITDSSLPTNSVSN 489

Query: 541  QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG 600
            +QP  ALTRV SVSQPGVRPAC  + L++G FSAG +PC TS+ LGSTDTIL+G+N I G
Sbjct: 490  RQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTILLGSNCIAG 549

Query: 601  SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL 660
            S SNGNVPYLQ+N  TLPHN T+L SS EEPW+ QLSNS QGLHK QSS  +GPN E+PL
Sbjct: 550  SESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPL 609

Query: 661  SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP 720
             STG +Q+ QA  +GI+  N H TLPSNSV QG A +HLS HTATSGGQQGI  TKESKP
Sbjct: 610  FSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKP 669

Query: 721  SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL 780
            S N   VPETSRHTG+T N  A V+GL NHVHQ+ ADAV SP+HGDS  P LL +DNPQL
Sbjct: 670  SKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDS--PNLLIADNPQL 727

Query: 781  SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS 840
            SALL+GKAN NVGTGTCDKVNNIHPAVHTKTD+SVASSPSSAISTATPSPKSTEQ + NS
Sbjct: 728  SALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINS 787

Query: 841  VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC 900
            VTSLNSPHSGLHT+NGEG+ +SQS  K DL L +H+ + QI+PSMSVSI PSS EVLKAC
Sbjct: 788  VTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSSTEVLKAC 847

Query: 901  RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC 960
            RN GKNGLSNS ILLDKCPPPRPP+SPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
Sbjct: 848  RNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC 907

Query: 961  TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI 1020
            TNP NPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
Sbjct: 908  TNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI 967

Query: 1021 WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK 1080
            W CESNRSHTTIAKYAQYQASSFQESLREENEKR+ HKDHSD+ESTSS+NSGRRRKGPFK
Sbjct: 968  WRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGRRRKGPFK 1027

Query: 1081 TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG 1140
            TIKFGTNIDLSD+KKWKLQLHELTKLPAF RVVSAGNLL+HVGHTILGMNTVQLYMKVPG
Sbjct: 1028 TIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQLYMKVPG 1087

Query: 1141 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL 1200
            SRTPGHQENNNFCSVNINIGPGDCEWFVVPE YWGVLNDFCEKNNLNFLM SWWPNLEDL
Sbjct: 1088 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNNLNFLMSSWWPNLEDL 1147

Query: 1201 YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK 1260
            YEANVPVYRFIQRPGDLVWINAGTVHWVQA+GWCNNIAWNVGPLTACQYKLAVERYEWNK
Sbjct: 1148 YEANVPVYRFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTACQYKLAVERYEWNK 1207

Query: 1261 LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWH 1320
            L+SVKS VPMVHLSWNMARNIKVSDPKLFEMIKYCLL+ LKQ QTLREAL+AAGKE+IWH
Sbjct: 1208 LKSVKSPVPMVHLSWNMARNIKVSDPKLFEMIKYCLLKILKQYQTLREALVAAGKEVIWH 1267

Query: 1321 GRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKM 1380
            GRT +EPAHYCSICEVEVF+LLFVTNESN++KTYIVHC DCARKTS +LENFVVLEQYKM
Sbjct: 1268 GRTNDEPAHYCSICEVEVFNLLFVTNESNTQKTYIVHCHDCARKTSKSLENFVVLEQYKM 1327

Query: 1381 EDLMQVYDQFTLAPPLPSAS 1400
            EDL+QVYDQFTLA  L S+S
Sbjct: 1328 EDLIQVYDQFTLALSLSSSS 1347


>gi|33188427 tetratricopeptide repeat protein isoform 2 [Homo sapiens]
          Length = 1240

 Score = 2160 bits (5598), Expect = 0.0
 Identities = 1077/1293 (83%), Positives = 1133/1293 (87%), Gaps = 53/1293 (4%)

Query: 1    MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV 60
            MKSC VSL TAA A   FGDE KKMA GKAS ESEE S SLT EEREALGG+DSRLFGFV
Sbjct: 1    MKSCAVSLTTAAVA---FGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFV 57

Query: 61   RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY 120
            R HEDGARTK LLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDY KALSAYQRYY
Sbjct: 58   RLHEDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYY 117

Query: 121  SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN 180
            SLQ+DYWKNAAFLYGLGLVYF+YNAF WAIKAFQ+VLYVDPSFCRAKEIHLRLGLMFKVN
Sbjct: 118  SLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVN 177

Query: 181  TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ 240
            TDY+SSLKHFQLAL+DCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENL AQ
Sbjct: 178  TDYKSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQ 237

Query: 241  VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV 300
            VKATVLQQLGWMHH +DL+GDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
Sbjct: 238  VKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV 297

Query: 301  QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT 360
            QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
Sbjct: 298  QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT 357

Query: 361  LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE 420
            LYESCNQPQDAIKCYLNA RSK CSNTS LAARIK+LQ                      
Sbjct: 358  LYESCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQ---------------------- 395

Query: 421  EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL 480
                                   N SDNW+GG ++SH PVQQ  +S CLTPQKLQHLEQL
Sbjct: 396  -----------------------NGSDNWNGGQSLSHHPVQQ-VYSLCLTPQKLQHLEQL 431

Query: 481  RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG 540
            RANR+NLNPAQK  LEQLESQFVLMQQ  MR   VAQVR+TGI NG   DSSLPTNSVS 
Sbjct: 432  RANRDNLNPAQKHQLEQLESQFVLMQQ--MRHKEVAQVRTTGIHNGAITDSSLPTNSVSN 489

Query: 541  QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG 600
            +QP  ALTRV SVSQPGVRPAC  + L++G FSAG +PC TS+ LGSTDTIL+G+N I G
Sbjct: 490  RQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTILLGSNCIAG 549

Query: 601  SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL 660
            S SNGNVPYLQ+N  TLPHN T+L SS EEPW+ QLSNS QGLHK QSS  +GPN E+PL
Sbjct: 550  SESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPL 609

Query: 661  SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP 720
             STG +Q+ QA  +GI+  N H TLPSNSV QG A +HLS HTATSGGQQGI  TKESKP
Sbjct: 610  FSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKP 669

Query: 721  SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL 780
            S N   VPETSRHTG+T N  A V+GL NHVHQ+ ADAV SP+HGDS  P LL +DNPQL
Sbjct: 670  SKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDS--PNLLIADNPQL 727

Query: 781  SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS 840
            SALL+GKAN NVGTGTCDKVNNIHPAVHTKTD+SVASSPSSAISTATPSPKSTEQ + NS
Sbjct: 728  SALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINS 787

Query: 841  VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC 900
            VTSLNSPHSGLHT+NGEG+ +SQS  K DL L +H+ + QI+PSMSVSI PSS EVLKAC
Sbjct: 788  VTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSSTEVLKAC 847

Query: 901  RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC 960
            RN GKNGLSNS ILLDKCPPPRPP+SPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
Sbjct: 848  RNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC 907

Query: 961  TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI 1020
            TNP NPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
Sbjct: 908  TNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI 967

Query: 1021 WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK 1080
            W CESNRSHTTIAKYAQYQASSFQESLREENEKR+ HKDHSD+ESTSS+NSGRRRKGPFK
Sbjct: 968  WRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGRRRKGPFK 1027

Query: 1081 TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG 1140
            TIKFGTNIDLSD+KKWKLQLHELTKLPAF RVVSAGNLL+HVGHTILGMNTVQLYMKVPG
Sbjct: 1028 TIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQLYMKVPG 1087

Query: 1141 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL 1200
            SRTPGHQENNNFCSVNINIGPGDCEWFVVPE YWGVLNDFCEKNNLNFLM SWWPNLEDL
Sbjct: 1088 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNNLNFLMSSWWPNLEDL 1147

Query: 1201 YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK 1260
            YEANVPVYRFIQRPGDLVWINAGTVHWVQA+GWCNNIAWNVGPLTACQYKLAVERYEWNK
Sbjct: 1148 YEANVPVYRFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTACQYKLAVERYEWNK 1207

Query: 1261 LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIK 1293
            L+SVKS VPMVHLSWNMARNIKVSDPKLFEMIK
Sbjct: 1208 LKSVKSPVPMVHLSWNMARNIKVSDPKLFEMIK 1240


>gi|33188429 tetratricopeptide repeat protein isoform 1 [Homo sapiens]
          Length = 1079

 Score = 1660 bits (4298), Expect = 0.0
 Identities = 844/1048 (80%), Positives = 893/1048 (85%), Gaps = 53/1048 (5%)

Query: 1    MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV 60
            MKSC VSL TAA A   FGDE KKMA GKAS ESEE S SLT EEREALGG+DSRLFGFV
Sbjct: 1    MKSCAVSLTTAAVA---FGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFV 57

Query: 61   RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY 120
            R HEDGARTK LLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDY KALSAYQRYY
Sbjct: 58   RLHEDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYY 117

Query: 121  SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN 180
            SLQ+DYWKNAAFLYGLGLVYF+YNAF WAIKAFQ+VLYVDPSFCRAKEIHLRLGLMFKVN
Sbjct: 118  SLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVN 177

Query: 181  TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ 240
            TDY+SSLKHFQLAL+DCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENL AQ
Sbjct: 178  TDYKSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQ 237

Query: 241  VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV 300
            VKATVLQQLGWMHH +DL+GDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
Sbjct: 238  VKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV 297

Query: 301  QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT 360
            QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
Sbjct: 298  QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT 357

Query: 361  LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE 420
            LYESCNQPQDAIKCYLNA RSK CSNTS LAARIK+LQ                      
Sbjct: 358  LYESCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQ---------------------- 395

Query: 421  EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL 480
                                   N SDNW+GG ++SH PVQQ  +S CLTPQKLQHLEQL
Sbjct: 396  -----------------------NGSDNWNGGQSLSHHPVQQ-VYSLCLTPQKLQHLEQL 431

Query: 481  RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG 540
            RANR+NLNPAQK  LEQLESQFVLMQQ  MR   VAQVR+TGI NG   DSSLPTNSVS 
Sbjct: 432  RANRDNLNPAQKHQLEQLESQFVLMQQ--MRHKEVAQVRTTGIHNGAITDSSLPTNSVSN 489

Query: 541  QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG 600
            +QP  ALTRV SVSQPGVRPAC  + L++G FSAG +PC TS+ LGSTDTIL+G+N I G
Sbjct: 490  RQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTILLGSNCIAG 549

Query: 601  SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL 660
            S SNGNVPYLQ+N  TLPHN T+L SS EEPW+ QLSNS QGLHK QSS  +GPN E+PL
Sbjct: 550  SESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPL 609

Query: 661  SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP 720
             STG +Q+ QA  +GI+  N H TLPSNSV QG A +HLS HTATSGGQQGI  TKESKP
Sbjct: 610  FSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKP 669

Query: 721  SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL 780
            S N   VPETSRHTG+T N  A V+GL NHVHQ+ ADAV SP+HGDS  P LL +DNPQL
Sbjct: 670  SKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDS--PNLLIADNPQL 727

Query: 781  SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS 840
            SALL+GKAN NVGTGTCDKVNNIHPAVHTKTD+SVASSPSSAISTATPSPKSTEQ + NS
Sbjct: 728  SALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINS 787

Query: 841  VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC 900
            VTSLNSPHSGLHT+NGEG+ +SQS  K DL L +H+ + QI+PSMSVSI PSS EVLKAC
Sbjct: 788  VTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSSTEVLKAC 847

Query: 901  RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC 960
            RN GKNGLSNS ILLDKCPPPRPP+SPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
Sbjct: 848  RNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC 907

Query: 961  TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI 1020
            TNP NPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
Sbjct: 908  TNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI 967

Query: 1021 WHCESNRSHTTIAKYAQYQASSFQESLR 1048
            W CESNRSHTTIAKYAQYQASSFQESLR
Sbjct: 968  WRCESNRSHTTIAKYAQYQASSFQESLR 995


>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
          Length = 1682

 Score =  711 bits (1834), Expect = 0.0
 Identities = 333/506 (65%), Positives = 409/506 (80%), Gaps = 2/506 (0%)

Query: 887  VSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLE 946
            ++I   +A+V++A RN    G    S L       +P  +    LP++KLNPPTPSIYLE
Sbjct: 1133 LTISHCAADVVRASRNAKVKGKFRESYL-SPAQSVKPKINTEEKLPREKLNPPTPSIYLE 1191

Query: 947  NKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQ 1006
            +KRDAF P L QFCT+P NP+TVIRGLAG+L+L+LGLFSTKTLVEA+ EH VEVRTQ+ Q
Sbjct: 1192 SKRDAFSPVLLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQ 1251

Query: 1007 PADENWDPTGTKKIWHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSEST 1066
            P+DENWD TGT++IW CES+RSHTTIAKYAQYQASSFQESL+EE E      +  DS + 
Sbjct: 1252 PSDENWDLTGTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEEKESEDEESEEPDSTTG 1311

Query: 1067 SSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTI 1126
            +  +S    K     IKFGTNIDLSD K+WK QL EL KLPAF+RV S GN+LSHVGHTI
Sbjct: 1312 TPPSSAPDPKN-HHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTI 1370

Query: 1127 LGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNL 1186
            LGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWF V E YW  ++ FC+++ +
Sbjct: 1371 LGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGV 1430

Query: 1187 NFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTA 1246
            ++L GSWWP L+DLY +N+PVYRF+QRPGDLVWINAGTVHWVQA GWCNNIAWNVGPLTA
Sbjct: 1431 DYLTGSWWPILDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTA 1490

Query: 1247 CQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTL 1306
             QY+LA+ERYEWN++++VKSIVPM+H+SWN+AR +K+SDP LF+MIK+CLL+++K CQ  
Sbjct: 1491 YQYQLALERYEWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQ 1550

Query: 1307 REALIAAGKEIIWHGRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTS 1366
            RE+L+ AGK+I + GR K+EPA+YC+ C+VEVF++LFVT+E+ SR TY+VHC+ CAR+ S
Sbjct: 1551 RESLVRAGKKIAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRS 1610

Query: 1367 GNLENFVVLEQYKMEDLMQVYDQFTL 1392
              L+  VVLEQY+ E+L Q YD FTL
Sbjct: 1611 AGLQGVVVLEQYRTEELAQAYDAFTL 1636



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 52/181 (28%), Positives = 83/181 (45%), Gaps = 9/181 (4%)

Query: 252 MHHTVDLLGDKATKESYAIQYLQ-----KSLEADPNSGQSWYFLGRCYSSIGKVQ-DAFI 305
           MH  VD  G +A +E++A+  L       S    P    +W   GRC +SIG+    A +
Sbjct: 1   MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL 60

Query: 306 SYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESC 365
                      S   +       +  +  +++L   + A+  +      W  LG LYES 
Sbjct: 61  PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE 120

Query: 366 NQPQDAIKCYLNATRSKSCSNTSALAARIKYLQ-AQLCNLPQGSLQNKTKLLPSIEEAWS 424
           +  ++A +CY +A R     + + L  RI  LQ AQL N   GS Q++ K+LP +E+ W+
Sbjct: 121 HDSEEATRCYHSALRYGG--SFAELGPRIGRLQQAQLWNFHTGSCQHRAKVLPPLEQVWN 178

Query: 425 L 425
           L
Sbjct: 179 L 179



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 38/138 (27%), Positives = 59/138 (42%), Gaps = 18/138 (13%)

Query: 809 TKTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKT 868
           ++ D+SV+ + ++A     PS       TT S +S +S ++GL      G+E +      
Sbjct: 368 SRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLR-----GVEPNPGIPGA 422

Query: 869 DLLLVNHKPSPQIIPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPPSSPY 928
           D     H  +P +  S    + PS+    K    LG    +    L     PP P S P 
Sbjct: 423 D-----HYQTPALEVSHHGRLGPSAHSSRKPF--LGAPAATPHLSL-----PPGPSSPPP 470

Query: 929 PPLPKDKLNPPTPSIYLE 946
           PP P+  L PP P  +L+
Sbjct: 471 PPCPR-LLRPPPPPAWLK 487



 Score = 30.8 bits (68), Expect = 9.5
 Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 4/40 (10%)

Query: 919 PPPRPPSSPYPPLPKDKLNPP----TPSIYLENKRDAFFP 954
           PPP PP  P PPLP    +PP     P ++     DA+ P
Sbjct: 253 PPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGP 292


>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
          Length = 1036

 Score = 58.2 bits (139), Expect = 6e-08
 Identities = 71/336 (21%), Positives = 142/336 (42%), Gaps = 47/336 (13%)

Query: 76  AVRCYESLILKAEGKVESDFFC---QLGHFNLLLEDYPKALSAYQRYYSLQSDY---WKN 129
           AV+ Y S +     +   D +C    LG+    L    +A + Y +    Q ++   W N
Sbjct: 132 AVQAYVSAL-----QYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSN 186

Query: 130 AAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVNTDYESSLKH 189
                 LG V+        AI  F++ + +DP+F  A   ++ LG + K    ++ ++  
Sbjct: 187 ------LGCVFNAQGEIWLAIHHFEKAVTLDPNFLDA---YINLGNVLKEARIFDRAVAA 237

Query: 190 FQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTE--------NLSAQV 241
           +  AL      + ++A +  ++A +Y  Q     A + Y + ++ +        NL+  +
Sbjct: 238 YLRAL----SLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANAL 293

Query: 242 KA------------TVLQQLGWMHHTVDLLGDKATKESY---AIQYLQKSLEADPNSGQS 286
           K             T L+       +++ L +   ++     A++  +K+LE  P    +
Sbjct: 294 KEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAA 353

Query: 287 WYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQ 346
              L       GK+Q+A + Y+++I  S   AD + ++G   ++      ALQ Y  A+Q
Sbjct: 354 HSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQ 413

Query: 347 LDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSK 382
           ++   A A  +L ++++      +AI  Y  A + K
Sbjct: 414 INPAFADAHSNLASIHKDSGNIPEAIASYRTALKLK 449



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 25/107 (23%), Positives = 51/107 (47%)

Query: 276 SLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPM 335
           +++ +P   +++  LG  Y   G++Q+A   YR ++       D + ++           
Sbjct: 71  AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDME 130

Query: 336 DALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSK 382
            A+QAY+ A+Q +        DLG L ++  + ++A  CYL A  ++
Sbjct: 131 GAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQ 177



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 50/253 (19%), Positives = 99/253 (39%), Gaps = 31/253 (12%)

Query: 94  DFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAAFLYG-LGLVYFHYNAFQWAIKA 152
           D +  LG+       + +A++AY R  SL      N A ++G L  VY+       AI  
Sbjct: 216 DAYINLGNVLKEARIFDRAVAAYLRALSLSP----NHAVVHGNLACVYYEQGLIDLAIDT 271

Query: 153 FQEVLYVDPSF----CRAKEIHLRLGLMFKVNTDYESSLKHFQLALVDCNPCTLSN-AEI 207
           ++  + + P F    C         G + +    Y ++L+     L   +  +L+N A I
Sbjct: 272 YRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALR-----LCPTHADSLNNLANI 326

Query: 208 QFHIAHLYETQRKYHSAKEAYEQLLQTE-NLSAQVKATVLQQLGWMHHTVDLLGDKATKE 266
           +    ++ E  R Y  A E + +      NL++ ++     Q   MH+   +       +
Sbjct: 327 KREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFAD 386

Query: 267 SY---------------AIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSI 311
           +Y               A+Q   ++++ +P    +   L   +   G + +A  SYR ++
Sbjct: 387 AYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTAL 446

Query: 312 DKSEASADTWCSI 324
                  D +C++
Sbjct: 447 KLKPDFPDAYCNL 459


>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
          Length = 1046

 Score = 58.2 bits (139), Expect = 6e-08
 Identities = 71/336 (21%), Positives = 142/336 (42%), Gaps = 47/336 (13%)

Query: 76  AVRCYESLILKAEGKVESDFFC---QLGHFNLLLEDYPKALSAYQRYYSLQSDY---WKN 129
           AV+ Y S +     +   D +C    LG+    L    +A + Y +    Q ++   W N
Sbjct: 142 AVQAYVSAL-----QYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSN 196

Query: 130 AAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVNTDYESSLKH 189
                 LG V+        AI  F++ + +DP+F  A   ++ LG + K    ++ ++  
Sbjct: 197 ------LGCVFNAQGEIWLAIHHFEKAVTLDPNFLDA---YINLGNVLKEARIFDRAVAA 247

Query: 190 FQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTE--------NLSAQV 241
           +  AL      + ++A +  ++A +Y  Q     A + Y + ++ +        NL+  +
Sbjct: 248 YLRAL----SLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANAL 303

Query: 242 KA------------TVLQQLGWMHHTVDLLGDKATKESY---AIQYLQKSLEADPNSGQS 286
           K             T L+       +++ L +   ++     A++  +K+LE  P    +
Sbjct: 304 KEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAA 363

Query: 287 WYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQ 346
              L       GK+Q+A + Y+++I  S   AD + ++G   ++      ALQ Y  A+Q
Sbjct: 364 HSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQ 423

Query: 347 LDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSK 382
           ++   A A  +L ++++      +AI  Y  A + K
Sbjct: 424 INPAFADAHSNLASIHKDSGNIPEAIASYRTALKLK 459



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 25/107 (23%), Positives = 51/107 (47%)

Query: 276 SLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPM 335
           +++ +P   +++  LG  Y   G++Q+A   YR ++       D + ++           
Sbjct: 81  AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDME 140

Query: 336 DALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSK 382
            A+QAY+ A+Q +        DLG L ++  + ++A  CYL A  ++
Sbjct: 141 GAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQ 187



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 50/253 (19%), Positives = 99/253 (39%), Gaps = 31/253 (12%)

Query: 94  DFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAAFLYG-LGLVYFHYNAFQWAIKA 152
           D +  LG+       + +A++AY R  SL      N A ++G L  VY+       AI  
Sbjct: 226 DAYINLGNVLKEARIFDRAVAAYLRALSLSP----NHAVVHGNLACVYYEQGLIDLAIDT 281

Query: 153 FQEVLYVDPSF----CRAKEIHLRLGLMFKVNTDYESSLKHFQLALVDCNPCTLSN-AEI 207
           ++  + + P F    C         G + +    Y ++L+     L   +  +L+N A I
Sbjct: 282 YRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALR-----LCPTHADSLNNLANI 336

Query: 208 QFHIAHLYETQRKYHSAKEAYEQLLQTE-NLSAQVKATVLQQLGWMHHTVDLLGDKATKE 266
           +    ++ E  R Y  A E + +      NL++ ++     Q   MH+   +       +
Sbjct: 337 KREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFAD 396

Query: 267 SY---------------AIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSI 311
           +Y               A+Q   ++++ +P    +   L   +   G + +A  SYR ++
Sbjct: 397 AYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTAL 456

Query: 312 DKSEASADTWCSI 324
                  D +C++
Sbjct: 457 KLKPDFPDAYCNL 469


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 58.2 bits (139), Expect = 6e-08
 Identities = 93/429 (21%), Positives = 149/429 (34%), Gaps = 59/429 (13%)

Query: 529  ADSSLPTNSVSGQQPQLALTRVPSV-SQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGS 587
            ++ S PT ++    P   L    S  + P + P   G   A+  FS    P S      S
Sbjct: 1475 SNHSAPTGTIP---PPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSS 1531

Query: 588  TDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQ 647
            T      +  +T + +    P         P   TN  +S+  P                
Sbjct: 1532 TH-----HPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPP-------------PPF 1573

Query: 648  SSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHP--TLPSNSVTQGAALNHLSSHT-- 703
            ++HS  P G  P SSTGP        +       HP  TLP++      +L   S+HT  
Sbjct: 1574 TTHSP-PTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVI 1632

Query: 704  ATSGGQQGITLTKESKPSGNILTVPETSRHTGET---PNSTASVEGLPNHVHQMTADAVC 760
              +  Q   + +  S P+G I   P T + TG T   P  T +  G    +  +      
Sbjct: 1633 TPTHAQMATSASIHSMPTGTI-PPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTS 1691

Query: 761  SPSHGDSKS---------------PGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHP 805
            +  H  + S               P   S+  P ++    G + +     T     ++H 
Sbjct: 1692 TSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHS 1751

Query: 806  AVHTKTDNSVASSPSSAIS-------TATPSPKSTEQTTTNSVT--SLNSPHSGLHTING 856
               +     V S+ +++I+       T TP   +T  T++   T  + +SP +G   I+ 
Sbjct: 1752 HTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISS 1811

Query: 857  EGMEESQSPMKTDLLLV---NHKPSPQIIPSMSVS-IYPSSAEVLKACRNLGKNGLSNSS 912
             G   + S   T         H   P  +PS S S + PS+  V+           S  S
Sbjct: 1812 TGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHS 1871

Query: 913  ILLDKCPPP 921
            +     PPP
Sbjct: 1872 MPTGTIPPP 1880



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 91/379 (24%), Positives = 144/379 (37%), Gaps = 61/379 (16%)

Query: 512  PTGVAQVRSTG--------------IPNGP--TADSSLPTNSVSGQQPQLALTRVPSVSQ 555
            PTG   + STG               P+ P  T  + +P+ S S   P      +P+ +Q
Sbjct: 1803 PTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQ 1862

Query: 556  PGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNAL 615
                 +    P    P      P +T +  GST T        +G+  + +     + + 
Sbjct: 1863 MATSASIHSMPTGTIP------PPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTST 1916

Query: 616  TLPHNR-------------TNLT-----SSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGE 657
            +LP++              TN+T     +    P  +  S S+  L    ++HS  P G 
Sbjct: 1917 SLPYHTSSTHHPEVTPTSTTNITPKHTSTGTRTPVAHTTSASSSRLPTPFTTHSP-PTGS 1975

Query: 658  RPLSSTGPSQHLQAAGSGIQNQNGHP--TLPSNSVTQGAALNHLSSHTA--TSGGQQGIT 713
             P SSTGP        +       HP  TLP++      +L   S+HT   T+  Q   +
Sbjct: 1976 SPFSSTGPMTATSFQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVIITTHTQMATS 2035

Query: 714  LTKESKPSGNILTVPETSRHTGET---PNSTASVEGLPNHVHQMTADAVCSPSHGDSKS- 769
             +  S P+G +   P T + TG T   P  T +  G  +  H   + A  S S   S S 
Sbjct: 2036 ASIHSTPTGTV-PPPTTLKATGSTHTAPPMTVTTSGT-SQTHSSFSTATASSSFISSSSW 2093

Query: 770  PGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPS--SAISTAT 827
                SS  P  S +     + +  T      N +         +S + SPS  S +S+  
Sbjct: 2094 LPQNSSSRPPSSPITTQLPHLSSATTPVSTTNQL--------SSSFSPSPSAPSTVSSYV 2145

Query: 828  PSPKSTEQTTTNSVTSLNS 846
            PS  S+ QT++ SV + +S
Sbjct: 2146 PSSHSSPQTSSPSVGTSSS 2164



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 114/528 (21%), Positives = 184/528 (34%), Gaps = 85/528 (16%)

Query: 524  PNGPTADSSLPTNS--VSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVP-CS 580
            P  P    S PT S   S   P  A +   + + P      P  P    P    HVP  S
Sbjct: 1569 PPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYP-----TPSHPQTTLPT---HVPPFS 1620

Query: 581  TSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNST 640
            TS    ST T++   +      ++ ++  +    +  P   T L ++        ++ +T
Sbjct: 1621 TSLVTPSTHTVITPTH--AQMATSASIHSMPTGTIPPP---TTLKATGSTHTAPTMTLTT 1675

Query: 641  QGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPT---LPSNSVTQGAALN 697
             G  +  SS +         S T  + H +A  +   N   +PT    P  +VT      
Sbjct: 1676 SGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVT------ 1729

Query: 698  HLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTAD 757
                   TSG  Q  +    +K S ++ +   ++ H   T  ST S+   PNH    T  
Sbjct: 1730 -------TSGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSIT--PNHTSTGTRT 1780

Query: 758  AVC-SPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTG---TCDKVNNIHPAVHTKTDN 813
             V  + S   S+ P   ++ +P      +        T    T       HP  HT    
Sbjct: 1781 PVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHP--HTTLPT 1838

Query: 814  SVASSPSSAISTATPS---PKSTEQTTTNSVTSL--------------NSPHSG---LHT 853
             V S  +S ++ +T +   P  T+  T+ S+ S+               S H+      T
Sbjct: 1839 HVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPT 1898

Query: 854  INGEGMEESQ-SPMKTDLLLVNHKPS---PQIIPSMSVSIYPSSAEVLKACRNLGKNGLS 909
             +G     S  S  KT   L  H  S   P++ P+ + +I P         R    +  S
Sbjct: 1899 TSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPTSTTNITPKHTST--GTRTPVAHTTS 1956

Query: 910  NSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNPNNPVTV 969
             SS  L     P P ++  PP      +   P      +    +P        P++P T 
Sbjct: 1957 ASSSRL-----PTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYP-------TPSHPQTT 2004

Query: 970  IRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGT 1017
                   L   +  FST  +  + +  ++   TQ+   A  +  PTGT
Sbjct: 2005 -------LPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGT 2045



 Score = 30.8 bits (68), Expect = 9.5
 Identities = 27/114 (23%), Positives = 45/114 (39%), Gaps = 15/114 (13%)

Query: 734  TGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVG 793
            TG +P+S        NH           P+   S  P   S + P+ +  +  +A + + 
Sbjct: 1236 TGPSPSS--------NHTPASPTQTPLLPATLTSSKPTASSGEPPRPTTAVTPQATSGLP 1287

Query: 794  TGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSP 847
                 +     P V   T  + AS       TA+P+  ST Q+TT +  +L +P
Sbjct: 1288 PTATLRSTATKPTVTQATTRATAS-------TASPATTSTAQSTTRTTMTLPTP 1334


>gi|118402596 cell division cycle protein 23 [Homo sapiens]
          Length = 597

 Score = 54.3 bits (129), Expect = 8e-07
 Identities = 32/110 (29%), Positives = 49/110 (44%)

Query: 269 AIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLY 328
           A  Y Q++L+ +P    +W  +G  Y  +     A  +YR +I+ ++     W  +G  Y
Sbjct: 350 AALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTY 409

Query: 329 QQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNA 378
           +    P   L  Y  A QL    +   + LG  YE  NQ  +A KCY  A
Sbjct: 410 EILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRA 459



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 59/286 (20%), Positives = 118/286 (41%), Gaps = 28/286 (9%)

Query: 94  DFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAF 153
           +FF  L H    L+   +AL  YQ    +   + K++  +  + + Y +      A+  F
Sbjct: 231 EFF--LAHIYTELQLIEEALQKYQNLIDV--GFSKSSYIVSQIAVAYHNIRDIDKALSIF 286

Query: 154 QEVLYVDPSFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALVDCNPCTLSNAEIQFH--I 211
            E+   DP   R + +     L+      Y  S+K  +L+ +  N C +    ++    I
Sbjct: 287 NELRKQDPY--RIENMDTFSNLL------YVRSMKS-ELSYLAHNLCEIDKYRVETCCVI 337

Query: 212 AHLYETQRKYHSAKEAYEQLLQTENLSAQVKATVLQQLG-WMHHTVDLLGDKATKESYAI 270
            + Y  + ++  A   +++ L+             + LG W     + +  K T  S AI
Sbjct: 338 GNYYSLRSQHEKAALYFQRALKLNP----------RYLGAWTLMGHEYMEMKNT--SAAI 385

Query: 271 QYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQ 330
           Q  + ++E +    ++WY LG+ Y  +         YR++       +    ++G  Y++
Sbjct: 386 QAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEK 445

Query: 331 QNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYL 376
            NQ ++A + Y  A  +      A + L  L+E   + + A +CY+
Sbjct: 446 LNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYI 491



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 37/198 (18%), Positives = 78/198 (39%), Gaps = 30/198 (15%)

Query: 208 QFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQVKATVLQQLGWMHHTV-------DLLG 260
           +F +AH+Y   +    A + Y+ L+   ++     + ++ Q+   +H +        +  
Sbjct: 231 EFFLAHIYTELQLIEEALQKYQNLI---DVGFSKSSYIVSQIAVAYHNIRDIDKALSIFN 287

Query: 261 DKATKESYAIQ-------------------YLQKSL-EADPNSGQSWYFLGRCYSSIGKV 300
           +   ++ Y I+                   YL  +L E D    ++   +G  YS   + 
Sbjct: 288 ELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQH 347

Query: 301 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT 360
           + A + +++++  +      W  +G  Y +      A+QAY  A++++     AW  LG 
Sbjct: 348 EKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQ 407

Query: 361 LYESCNQPQDAIKCYLNA 378
            YE    P   +  Y  A
Sbjct: 408 TYEILKMPFYCLYYYRRA 425



 Score = 38.5 bits (88), Expect = 0.046
 Identities = 44/235 (18%), Positives = 89/235 (37%), Gaps = 32/235 (13%)

Query: 155 EVLYVDPSFCRAKEIHLR----LGLMFKVNTDYESSLKHFQLALVDCNPCTLSNAEIQFH 210
           E+ Y+  + C   +  +     +G  + + + +E +  +FQ AL   NP  L    +   
Sbjct: 315 ELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRAL-KLNPRYLGAWTL--- 370

Query: 211 IAHLYETQRKYHSAKEAYEQLLQTENLSAQVKATVLQQLGW--MHHTVDLLGDKATKESY 268
           + H Y   +   +A +AY   ++      +          W  +  T ++L        Y
Sbjct: 371 MGHEYMEMKNTSAAIQAYRHAIEVNKRDYRA---------WYGLGQTYEIL----KMPFY 417

Query: 269 AIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLY 328
            + Y +++ +  PN  +    LG CY  + ++ +A   Y ++    +        +  L+
Sbjct: 418 CLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLH 477

Query: 329 QQQNQPMDALQAYI--------CAVQLDH-GHAAAWMDLGTLYESCNQPQDAIKC 374
           +Q  +   A Q YI        C   ++H   + A+  L   Y  C    +A  C
Sbjct: 478 EQLTESEQAAQCYIKYIQDIYSCGEIVEHLEESTAFRYLAQYYFKCKLWDEASTC 532


>gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens]
          Length = 519

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 52/246 (21%), Positives = 104/246 (42%), Gaps = 21/246 (8%)

Query: 96  FCQLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQE 155
           +  LG  +LL  D  KA+  Y++      +   N   L  LGL+Y     +Q A +    
Sbjct: 171 YIMLGKIHLLEGDLDKAIEVYKKAVEFSPE---NTELLTTLGLLYLQLGIYQKAFEHLGN 227

Query: 156 VLYVDPSFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLY 215
            L  DP+  +A    L  G M + + D++ +L  ++  +V C      +  +  +I   +
Sbjct: 228 ALTYDPTNYKA---ILAAGSMMQTHGDFDVALTKYR--VVAC--AVPESPPLWNNIGMCF 280

Query: 216 ETQRKYHSAKEAYEQLLQTENLSAQVKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQK 275
             ++KY +A       L+  N  A     +L  LG +H T+        + + A  +L  
Sbjct: 281 FGKKKYVAAISC----LKRANYLAPFDWKILYNLGLVHLTMQ-------QYASAFHFLSA 329

Query: 276 SLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPM 335
           ++   P  G+ +  L    +++  +++A  +Y +++   + +     +  VL   Q +  
Sbjct: 330 AINFQPKMGELYMLLAVALTNLEDIENAKRAYAEAVHLDKCNPLVNLNYAVLLYNQGEKK 389

Query: 336 DALQAY 341
           +AL  Y
Sbjct: 390 NALAQY 395


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 60/277 (21%), Positives = 106/277 (38%), Gaps = 17/277 (6%)

Query: 581 TSRTLGSTDTILIGNNHITGSG----SNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQL 636
           +S T     T  I  + +T +G    +N           T  ++  +  SS      N  
Sbjct: 50  SSVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSE 109

Query: 637 SNSTQ-GLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAA 695
           S++T  G     +S S+ P+     ++   S    +  S   N +   T    S    + 
Sbjct: 110 SSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSE 169

Query: 696 LNHLSSHTATSGGQQGITLTKESKPSGNI---LTVPETSRHTGETPNSTASVEGLPNHVH 752
            +  SS  +T+   +  T++  +  + N     T    S  T     +T++  G   +  
Sbjct: 170 SSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSE 229

Query: 753 QMTADAVCSP---SHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHT 809
             T  +  S    S   + S G  ++ N + S    G      GT T  + + +   + T
Sbjct: 230 SSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSG-----AGTATNSESSTVSSGIST 284

Query: 810 KTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSLNS 846
            T NS +S+PSS  +TAT S  ST  +  N+ T+ +S
Sbjct: 285 VT-NSESSTPSSGANTATNSESSTTSSGANTATNSDS 320



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 80/347 (23%), Positives = 127/347 (36%), Gaps = 37/347 (10%)

Query: 527 PTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLG 586
           P++ +S  TNS S      A T   S S      A       +   S+G    + S +  
Sbjct: 128 PSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESST 187

Query: 587 STDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKG 646
            +       N  + + S+G        A T  ++ +  TS+      N  S++T      
Sbjct: 188 VSSRASTATNSESSTTSSG--------ASTATNSESRTTSNGAGTATNSESSTTS----- 234

Query: 647 QSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPT-LPSNSVTQGAALNHLSSHTAT 705
            S  S   N E    S+G      +  S   +  G  T   S++V+ G +    S  +  
Sbjct: 235 -SGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTP 293

Query: 706 SGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHG 765
           S G    T ++ S  S    T   +   T  +  STA+     N     T+    + ++ 
Sbjct: 294 SSGANTATNSESSTTSSGANTATNSDSSTTSSGASTAT-----NSESSTTSSGASTATNS 348

Query: 766 DSK--SPGLLSSDNPQLSALLMGKA----------NNNVGTGTCDKVNNIHPAVHTKTDN 813
           +S   S G  ++ N   S    G +          ++   T T  + +       T T N
Sbjct: 349 ESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTAT-N 407

Query: 814 SVASSPSSAISTATPSPKST----EQTTTNSVTSLNSPHSGLHTING 856
           S +S+ SS  STAT S  ST      T TNS +S+ S  SG   + G
Sbjct: 408 SESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTG 454



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 53/214 (24%), Positives = 84/214 (39%), Gaps = 30/214 (14%)

Query: 668 HLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTV 727
           HL+AA +  +      T  S+ ++ GA+    S  + TS G    T++  S  S  +  V
Sbjct: 17  HLEAATNSNETSTSANT-GSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIV 75

Query: 728 PETSRHTGETPNSTAS----------VEGLPNHVHQMTADAVCSPSHGDSKSP--GLLSS 775
             +  HT  +  STA+          +    N     T+    + ++ +S +P  G  ++
Sbjct: 76  TNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTA 135

Query: 776 DNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKST-- 833
            N   S       ++   T T    +       T T NS +S+ SS  STAT S  ST  
Sbjct: 136 TNSDSST-----TSSGASTATNSDSSTTSSEASTAT-NSESSTTSSGASTATNSESSTVS 189

Query: 834 ---------EQTTTNSVTSLNSPHSGLHTINGEG 858
                    E +TT+S  S  +      T NG G
Sbjct: 190 SRASTATNSESSTTSSGASTATNSESRTTSNGAG 223



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 63/265 (23%), Positives = 104/265 (39%), Gaps = 22/265 (8%)

Query: 595 NNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNST-QGLHKGQSSHSAG 653
           N++ T + +N     +   A T  ++ +++TSS        +S +T  G     +  S  
Sbjct: 23  NSNETSTSANTGSSVISSGASTATNSGSSVTSSG-------VSTATISGSSVTSNGVSIV 75

Query: 654 PNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTAT-SGGQQGI 712
            N E   +S+G S    +  S + +     T   +S T   A    +S ++T S G    
Sbjct: 76  TNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTA 135

Query: 713 TLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGL 772
           T +  S  S    T   +   T  +  STA+     N     T+    + ++ +S +   
Sbjct: 136 TNSDSSTTSSGASTATNSDSSTTSSEASTAT-----NSESSTTSSGASTATNSESST--- 187

Query: 773 LSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKS 832
           +SS     +       ++   T T  +         T T NS +S+ SS  STAT S  S
Sbjct: 188 VSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTAT-NSESSTTSSGASTATNSESS 246

Query: 833 TEQ----TTTNSVTSLNSPHSGLHT 853
           T      T TNS +S  S  +G  T
Sbjct: 247 TPSSGAGTATNSESSTTSSGAGTAT 271



 Score = 37.0 bits (84), Expect = 0.13
 Identities = 42/173 (24%), Positives = 65/173 (37%), Gaps = 11/173 (6%)

Query: 581 TSRTLGSTDTILIGNNHITGSGS----NGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQL 636
           +S T    +T    ++  T SG+    N         A T  ++ ++ TSS      N  
Sbjct: 305 SSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSG 364

Query: 637 SNSTQ-GLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAA 695
           S++T  G     +S S+  +     ++T  S    +  S   N        S++V+ GA+
Sbjct: 365 SSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSE------SSTVSSGAS 418

Query: 696 LNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLP 748
               S  + TS G    T +  S  S    T   T  HT     STA  E  P
Sbjct: 419 TATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEAKP 471



 Score = 31.6 bits (70), Expect = 5.6
 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 5/85 (5%)

Query: 789 NNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPS----PKSTEQTTTNSVTSL 844
           ++ + T T  + + +   +   T NS +S+ SS  STAT S    P S   T TNS +S 
Sbjct: 84  SSGISTATNSEFSTVSSGISIAT-NSESSTTSSGASTATNSESSTPSSGASTATNSDSST 142

Query: 845 NSPHSGLHTINGEGMEESQSPMKTD 869
            S  +   T +      S++   T+
Sbjct: 143 TSSGASTATNSDSSTTSSEASTATN 167


>gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens]
          Length = 1564

 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 74/323 (22%), Positives = 126/323 (39%), Gaps = 49/323 (15%)

Query: 85  LKAEGKVESDFFC--QLGHFNLLLEDYPKALSAYQRYYSLQSD----YWKNAAFLYGLGL 138
           L+A+ K   DF C   LG   L    Y  AL ++ +   L  +     +K AA    LG 
Sbjct: 591 LRADPK---DFNCWESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAIQQILGK 647

Query: 139 VYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN------TDY-ESSLKHFQ 191
                  +Q  IK  ++ +   P+     E HL +     V+       DY E +L++F 
Sbjct: 648 YKEAVAQYQMIIKKKEDYV---PALKGLGECHLMMAKAALVDYLDGKAVDYIEKALEYFT 704

Query: 192 LAL-----VDC------NPCT----LSNAEIQFHIAHLYETQRKYHSAKEAYE------- 229
            AL     V C      + CT    ++ +++  H+  +   Q++     +  E       
Sbjct: 705 CALQHRADVSCLWKLAGDACTCLYAVAPSKVNVHVLGVLLGQKEGKQVLKKNELLHLGGR 764

Query: 230 ------QLLQTENLSAQVKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNS 283
                 +L+ T N    +     +Q   +  T   + D       ++  L+K++  D N+
Sbjct: 765 CYGRALKLMSTSNTWCDLGINYYRQAQHLAETGSNMNDLKELLEKSLHCLKKAVRLDSNN 824

Query: 284 GQSWYFLG--RCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAY 341
              W  LG   CYS IG    A   + +SI   + +A  W ++GVLY        A +A+
Sbjct: 825 HLYWNALGVVACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQAHEAF 884

Query: 342 ICAVQLDHGHAAAWMDLGTLYES 364
             A  LD  +   W+    + E+
Sbjct: 885 KMAQSLDPSYLMCWIGQALIAEA 907



 Score = 35.4 bits (80), Expect = 0.39
 Identities = 18/48 (37%), Positives = 22/48 (45%)

Query: 319 DTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCN 366
           + W  IGV   +  QP  A  AY  A +L+     AW  L  LYE  N
Sbjct: 41  NAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQGLANLYEKYN 88



 Score = 30.8 bits (68), Expect = 9.5
 Identities = 16/76 (21%), Positives = 38/76 (50%), Gaps = 2/76 (2%)

Query: 257 DLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEA 316
           D + +K  KE  A+++ +  L+ + N+  +W F+G   + + +   A  +Y+++ +    
Sbjct: 15  DAIRNKEYKE--ALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPD 72

Query: 317 SADTWCSIGVLYQQQN 332
               W  +  LY++ N
Sbjct: 73  QLLAWQGLANLYEKYN 88


>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
          Length = 2481

 Score = 50.8 bits (120), Expect = 9e-06
 Identities = 75/326 (23%), Positives = 137/326 (42%), Gaps = 60/326 (18%)

Query: 92  ESDFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDYWK---NAAFLYGLGLVYFHYNAFQW 148
           E+     LG+F+    +Y +A   Y++Y  L  D           + LG  ++    +Q 
Sbjct: 593 EARALSNLGNFHCSRGEYVQAAPYYEQYLRLAPDLQDMEGEGKVCHNLGYAHYCLGNYQE 652

Query: 149 AIKAFQEVLYVDPSFCRAKEIH---------LRLGLMFK--VNTDYESSLKHFQLALVDC 197
           A+K +++ L +      AK++H           LGL FK  +N       + + L+L   
Sbjct: 653 AVKYYEQDLAL------AKDLHDKLSQAKAYCNLGLAFKALLNFSKAEECQKYLLSLAQ- 705

Query: 198 NPCTLSNAEIQF----HIAHLYETQRKYHSAKEAYEQLLQTENLSAQVK-----ATVLQQ 248
              +L+N++ +F    ++  ++  ++  + A + YEQ L    L+ QVK     A+    
Sbjct: 706 ---SLNNSQAKFRALGNLGDIFICKKDINGAIKFYEQQL---GLAHQVKDRRLEASAYAA 759

Query: 249 LGWMHHTVDLLGDKATKESYAIQYLQ--KSLEADPNSGQSWYFLGRCYSSIGKVQDAFIS 306
           LG  +  +    DKA    Y  Q L+  + L   P   ++   L   Y ++GK   AF  
Sbjct: 760 LGTAYRMIQKY-DKAL--GYHTQELEVYQELSDLPGECRAHGHLAAVYMALGKYTMAFKC 816

Query: 307 YRQSIDKSEA------SADTWCSIGVLYQQQNQPMDAL---QAYICAVQ--------LDH 349
           Y + +D  +        A  + ++G+     N   +A+   +  +  +Q        LD 
Sbjct: 817 YEEQLDLGQKLKDPSLEAQVYGNMGITKMNMNVMEEAIGYFEQQLAMLQQLSGNESVLDR 876

Query: 350 GHAAAWMDLGTLYESCNQPQDAIKCY 375
           G A  + +LG  YE+    ++AIK Y
Sbjct: 877 GRA--YGNLGDCYEALGDYEEAIKYY 900



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 75/332 (22%), Positives = 137/332 (41%), Gaps = 42/332 (12%)

Query: 76   AVRCYESLILKA----EGKVESDFFCQLGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAA 131
            A++ YE  +  A    + ++E+  +  LG    +++ Y KAL     Y++ + + ++  +
Sbjct: 733  AIKFYEQQLGLAHQVKDRRLEASAYAALGTAYRMIQKYDKALG----YHTQELEVYQELS 788

Query: 132  FLYG-------LGLVYFHYNAFQWAIKAFQEVLYV-----DPSFCRAKEIHLRLGLMFKV 179
             L G       L  VY     +  A K ++E L +     DPS     +++  +G+    
Sbjct: 789  DLPGECRAHGHLAAVYMALGKYTMAFKCYEEQLDLGQKLKDPSL--EAQVYGNMGITKMN 846

Query: 180  NTDYESSLKHF--QLALVDC---NPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQT 234
                E ++ +F  QLA++     N   L       ++   YE    Y  A + YEQ L  
Sbjct: 847  MNVMEEAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLSV 906

Query: 235  -ENLSA-QVKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGR 292
             ++L+  Q +A   + LG  H  +  L          +    +  EA  N  Q++  LG 
Sbjct: 907  AQSLNRMQDQAKAYRGLGNGHRAMGSLQQALVCFEKRLVVAHELGEAF-NKAQAYGELGS 965

Query: 293  CYSSIGKVQDAFISYRQSID-----KSEA-SADTWCSIGVLYQQQNQPMDALQAYICAVQ 346
             +S +G  + A     + ++     K  A  +D  C +G +YQQ  +   ALQ +   +Q
Sbjct: 966  LHSQLGNYEQAISCLERQLNIARDMKDRALESDAACGLGGVYQQMGEYDTALQYHQLDLQ 1025

Query: 347  LDHG------HAAAWMDLGTLYESCNQPQDAI 372
            +            A+ +LG  YES    + A+
Sbjct: 1026 IAEETNNPTCQGRAYGNLGLTYESLGTFERAV 1057



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 75/359 (20%), Positives = 140/359 (38%), Gaps = 29/359 (8%)

Query: 1   MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV 60
           +K  G   +  ++A  + G+ EK     +   +  +     T E R A G L S  F   
Sbjct: 230 LKLRGSVFSALSSAYWSLGNTEKSTGYMQQDLDVAKTLGDQTGECR-AHGNLGSAFFSKG 288

Query: 61  RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY 120
            + E      AL     +   ++ LK + +  S     LGH    + DYP AL+++++  
Sbjct: 289 NYRE------ALTNHRHQLVLAMKLK-DREAASSALSSLGHVYTAIGDYPNALASHKQCV 341

Query: 121 SL---QSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKE---IHLRLG 174
            L     D    A  L  +G VY     F+ A++  ++ L +       +E    +  LG
Sbjct: 342 LLAKQSKDELSEARELGNMGAVYIAMGDFENAVQCHEQHLKIAKDLGNKREEARAYSNLG 401

Query: 175 LMFKVNTDYESSLKHFQLALVDCNPCTLSNAEIQFH--IAHLYETQRKYHSAKEAYEQLL 232
             +    +++ ++ +    L           E++ +  + H     +    AK+ +EQ L
Sbjct: 402 SAYHYRRNFDKAMSYHNYVLELAQELMEKAIEMRAYAGLGHAARCMQDLERAKQYHEQQL 461

Query: 233 ----QTENLSAQVKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWY 288
                 ++ +A+ +A+    LG +H       D A K       + + L      G+++ 
Sbjct: 462 GIAEDLKDRAAEGRAS--SNLGIIHQMKGDY-DTALKLHKTHLCIAQELSDYAAQGRAYG 518

Query: 289 FLGRCYSSIGKVQDAFISYRQSIDKS------EASADTWCSIGVLYQQQNQPMDALQAY 341
            +G  Y+++G    A   +RQ +  S       + A T  ++ V YQ       ALQ Y
Sbjct: 519 NMGNAYNALGMYDQAVKYHRQELQISMEVNDRASQASTHGNLAVAYQALGAHDRALQHY 577



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 71/333 (21%), Positives = 139/333 (41%), Gaps = 38/333 (11%)

Query: 75  KAVRCYESLILKAEGK----VESDFFCQLGHFNLLLEDYPKALSAYQRYYSL-QSDYWKN 129
           +AV+ YE  +  A+       ++  +C LG     L ++ KA    +   SL QS     
Sbjct: 652 EAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALLNFSKAEECQKYLLSLAQSLNNSQ 711

Query: 130 AAF--LYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAK---EIHLRLGLMFKVNTDYE 184
           A F  L  LG ++        AIK +++ L +       +     +  LG  +++   Y+
Sbjct: 712 AKFRALGNLGDIFICKKDINGAIKFYEQQLGLAHQVKDRRLEASAYAALGTAYRMIQKYD 771

Query: 185 SSLKHFQLALVDCNPCTLSNAEIQFH--IAHLYETQRKYHSAKEAYEQLLQTENLSAQVK 242
            +L +    L      +    E + H  +A +Y    KY  A + YE+ L   +L  ++K
Sbjct: 772 KALGYHTQELEVYQELSDLPGECRAHGHLAAVYMALGKYTMAFKCYEEQL---DLGQKLK 828

Query: 243 ATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSL---------EADPNSGQSWYFLGRC 293
              L+   + +  +  +     +E  AI Y ++ L         E+  + G+++  LG C
Sbjct: 829 DPSLEAQVYGNMGITKMNMNVMEE--AIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDC 886

Query: 294 YSSIGKVQDA------FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQL 347
           Y ++G  ++A      ++S  QS+++ +  A  +  +G  ++       AL  +   + +
Sbjct: 887 YEALGDYEEAIKYYEQYLSVAQSLNRMQDQAKAYRGLGNGHRAMGSLQQALVCFEKRLVV 946

Query: 348 DH------GHAAAWMDLGTLYESCNQPQDAIKC 374
            H        A A+ +LG+L+      + AI C
Sbjct: 947 AHELGEAFNKAQAYGELGSLHSQLGNYEQAISC 979


>gi|116805348 trinucleotide repeat containing 6A [Homo sapiens]
          Length = 1962

 Score = 50.8 bits (120), Expect = 9e-06
 Identities = 87/376 (23%), Positives = 141/376 (37%), Gaps = 50/376 (13%)

Query: 519 RSTGIPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLA-NGPFSAG-- 575
           +S    N   A  ++ ++S  G  P    + + S S  G  P      LA  GP  +G  
Sbjct: 334 KSESSNNRMNAWGTVSSSSNGGLNP----STLNSASNHGAWPVLENNGLALKGPVGSGSS 389

Query: 576 --HVPCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNA---------LTLPHNRTNL 624
             ++ CST   + +  +I   N+ ++G  ++G    LQ            ++      N+
Sbjct: 390 GINIQCSTIGQMPNNQSI---NSKVSGGSTHGTWGSLQETCESEVSGTQKVSFSGQPQNI 446

Query: 625 TSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPT 684
           T+    P     +N+T  +     +  +  N E P S+TG  +        +   N HP 
Sbjct: 447 TTEMTGP-----NNTTNFMTSSLPNSGSVQNNELPSSNTGAWR--------VSTMN-HPQ 492

Query: 685 LPSNSVTQGAALNHLSSHTATSGGQQGITL-TKESKPSGNILTVPETSRHTGETPNSTAS 743
           + + S   G +L+HLS+  + SGG  G T     S  SG+  + P   +  G+T N+T  
Sbjct: 493 MQAPSGMNGTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGP-NGQANGDTVNATLM 551

Query: 744 VEGLPN------HVHQMTADAVCSPSHGDSKSP--GLLSSDNPQLSALLMGKANNNVGTG 795
             G+         V+      V      +S+S   G  +  N   S    G    N GT 
Sbjct: 552 QPGVNGPMGTNFQVNTNKGGGVWESGAANSQSTSWGSGNGANSGGSRRGWGTPAQNTGTN 611

Query: 796 TCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTIN 855
                 N  P+     D++  +       T T   KSTE+    S TS  +  S +    
Sbjct: 612 LPSVEWNKLPSNQHSNDSANGNG-----KTFTNGWKSTEEEDQGSATSQTNEQSSVWAKT 666

Query: 856 GEGMEESQSPMKTDLL 871
           G  +E   S   T  L
Sbjct: 667 GGTVESDGSTESTGRL 682


>gi|224809432 transmembrane and tetratricopeptide repeat containing
           3 [Homo sapiens]
          Length = 914

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 49/217 (22%), Positives = 95/217 (43%), Gaps = 30/217 (13%)

Query: 177 FKVNTDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQL--LQT 234
           F  N D+ES    F  AL        +NA++  ++ H  E ++ +  A + + Q   +Q 
Sbjct: 422 FHRNWDWESEYTLFMSAL----KVNKNNAKLWNNVGHALENEKNFERALKYFLQATHVQP 477

Query: 235 ENLSAQVKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEAD------------PN 282
           +++ A +       +G  +  ++      TKE+     + KSL               PN
Sbjct: 478 DDIGAHMN------VGRTYKNLN-----RTKEAEESYMMAKSLMPQIIPGKKYAARIAPN 526

Query: 283 SGQSWYFLGRCY-SSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAY 341
               +  L     ++  ++++A   YRQ+I         + S G L  + N+P+ A +AY
Sbjct: 527 HLNVYINLANLIRANESRLEEADQLYRQAISMRPDFKQAYISRGELLLKMNKPLKAKEAY 586

Query: 342 ICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNA 378
           + A++LD  +A  W +L  ++    +P +A+K +  A
Sbjct: 587 LKALELDRNNADLWYNLAIVHIELKEPNEALKNFNRA 623


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 69/279 (24%), Positives = 101/279 (36%), Gaps = 49/279 (17%)

Query: 640 TQGLHKGQSSHSA--GPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALN 697
           T  L    SSH A  GP+G   LS TG      +  S      G  T  S S +   A  
Sbjct: 710 TTALQAAPSSHDATLGPSGGTSLSKTGALTLANSVVSTPGGPEGQWTSASASTSPDTAAA 769

Query: 698 HLSSHTATSGGQQGITLTKESKPSGNILT-----VPETSRHTGETPNSTASVE------- 745
              +H A S    G T T E   SG+  T      P +S  +G TP+ +  +        
Sbjct: 770 MTHTHQAESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTR 829

Query: 746 -----GLPNHVHQMTADAV-CSPSHGD-SKSPGLLSSDNPQLSALLMGKANN-------- 790
                   +H  Q T + +  S SHG    S G+ SS  P      + +A+         
Sbjct: 830 FSSNPSRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQS 889

Query: 791 -----NVGTGTCDKVNNIHPAVHTKTDN-----SVASSPSSAISTATPSPKSTEQTTTNS 840
                +        ++ +     T+T       S+AS  +   ST  P+P S       +
Sbjct: 890 SPTSPSASPQETAAISRMAQTQRTRTSRGSDTISLASQATDTFSTVPPTPPSI------T 943

Query: 841 VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSP 879
            T L SP +  HT++  G  ++     T  L+ N  P P
Sbjct: 944 STGLTSPQTETHTLSPSGSGKT----FTTALISNATPLP 978



 Score = 35.4 bits (80), Expect = 0.39
 Identities = 76/353 (21%), Positives = 132/353 (37%), Gaps = 34/353 (9%)

Query: 512  PTGVAQVRSTGIPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGP 571
            P  V    S    +  +   ++P+++ SG    L +T   SVS             +   
Sbjct: 1824 PLPVTDASSASTGDTTSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVST 1883

Query: 572  FSAGHVPCSTSRTLGSTDTILIGNNHIT--GSGSNGNVPYLQRNALTLPHNRTNLTSSAE 629
                 +P + + +  + DT  +   H+T   S S G+   L   +L+             
Sbjct: 1884 GDTTPLPVTDTNSASTGDTTPL---HVTDASSVSTGHATSLPVTSLSSASTGDTTPLPVT 1940

Query: 630  EPWKNQLSNSTQGLHKGQSSHSAGPNGERPLS-----STGPSQHLQAAGSGIQNQNGH-- 682
             P      ++T       SS   G     P++     STG +  L    +   +  GH  
Sbjct: 1941 SPSSASSGHTTPLPVTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVS-TGHAT 1999

Query: 683  --PTLPSNSVTQGAA--LNHLSSHTATSGGQQGITLTKESKPS-GNILTVPETSRHTGET 737
              P   ++SV+ G A  L   S  +A++G    + +T  S  S G    +P TS  +  T
Sbjct: 2000 PLPVTDTSSVSTGQATPLPVTSLSSASTGDTTPLPVTDTSSASTGQDTPLPVTSLSSVST 2059

Query: 738  PNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTC 797
             ++T     LP     +T+ +  S  H       LL +D   +S    G A + + T   
Sbjct: 2060 GDTTP----LP-----VTSPSSASTGHATP----LLVTDASSVST---GHATSLLVTDAS 2103

Query: 798  DKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSG 850
                    A+H    +S+++  ++ +   +PS  ST  TT   VT  +S  +G
Sbjct: 2104 SVSTGHATALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTDTSSVSTG 2156



 Score = 34.3 bits (77), Expect = 0.86
 Identities = 78/348 (22%), Positives = 131/348 (37%), Gaps = 51/348 (14%)

Query: 564 GQPLANGPFSAGHVPCSTSRTLG---STDTILIGNNHITGSGSNGNVPYLQRNALTLPHN 620
           G+   + P S  +    TS+      S D+ L GN   T    +G +  +     T+  +
Sbjct: 373 GETTTSSPSSVSNTFLVTSKVFRMPTSRDSTL-GNTEETSLSVSGTISAITSKVSTIWWS 431

Query: 621 RTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPLSSTGPSQ-----HLQAAGSG 675
            T  T+ +      ++S +     + + + + G   ER   S G SQ     H       
Sbjct: 432 DTLSTALSPSSLPPKISTAFH-TQQSEGAETTGRPHERSSFSPGVSQEIFTLHETTTWPS 490

Query: 676 IQNQNGHPT-----LPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPS--GNILTVP 728
             +  GH T     LPS S   GAA   ++ + +T  G  G      SK S  G      
Sbjct: 491 SFSSKGHTTWSQTELPSTST--GAATRLVTGNPST--GTAGTIPRVPSKVSAIGEPGEPT 546

Query: 729 ETSRHTGETPNSTASVEGLPNHVHQMTADA----VCSPSHGDSKSPGLLSSDNPQLSALL 784
             S H+   P +T +  G      Q T       + SPS+  S +  + ++ +P  S +L
Sbjct: 547 TYSSHSTTLPKTTGA--GAQTQWTQETGTTGEALLSSPSY--SVTQMIKTATSPSSSPML 602

Query: 785 MGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSL 844
               +  + T          P+ +  T +S ++SP  + + +        QTT  S T+ 
Sbjct: 603 DRHTSQQITTA---------PSTNHSTIHSTSTSPQESPAVSQRGHTQAPQTTQESQTTR 653

Query: 845 N-SPHSGLHTINGEGMEESQSPMKTDLLLVNHKPS---PQIIPSMSVS 888
           + SP +   T+   G   + S          H PS   PQ  P++S +
Sbjct: 654 SVSPMTDTKTVTTPGSSFTAS---------GHSPSEIVPQDAPTISAA 692



 Score = 34.3 bits (77), Expect = 0.86
 Identities = 73/335 (21%), Positives = 119/335 (35%), Gaps = 44/335 (13%)

Query: 535  TNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGH-----VPCSTSRTLGS-- 587
            +++ +GQ   L +T + SVS     P     P +    S GH     V  ++S + G   
Sbjct: 1367 SSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSA---STGHATPLLVTDTSSASTGHAT 1423

Query: 588  ----TDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGL 643
                TD   +  +H T       +P       T P   T+ +S++     + L   T  +
Sbjct: 1424 PLPVTDASSVSTDHATSLPVT--IPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSV 1481

Query: 644  HKGQ-------SSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAAL 696
              G        S+ SA      PL  T PS    +A +G        +L S S      L
Sbjct: 1482 STGDTTPLPVTSTSSASTGHVTPLHVTSPS----SASTGHATPLPVTSLSSASTGDTMPL 1537

Query: 697  NHLSSHTATSGGQQGITLTKESKPS-GNILTVPETSRHTGETPNSTASVEGLPNHVHQMT 755
               S  +A++G    + +T  S  S G+   +P TS  +  T            H   + 
Sbjct: 1538 PVTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSAST-----------GHTTPLP 1586

Query: 756  ADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSV 815
                 S S GD+    + S      S+   G       T T          +     +S+
Sbjct: 1587 VTDTSSASKGDTTPLPVTSP-----SSASTGHTTPLPVTDTSSASTGDTTPLPVTNASSL 1641

Query: 816  ASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSG 850
            ++  ++ +   +PS  ST   T   VTS +S  +G
Sbjct: 1642 STGHATPLHVTSPSSASTGHATPLPVTSTSSASTG 1676



 Score = 32.0 bits (71), Expect = 4.3
 Identities = 43/247 (17%), Positives = 89/247 (36%), Gaps = 11/247 (4%)

Query: 653 GPNGERPLSSTGPSQH-LQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQG 711
           G     P++STG +   L+   +   ++  +  + ++S          +S   T    Q 
Sbjct: 37  GSKTAAPVTSTGSTTATLEGQSTAASSRTSNQDISASSQNHQTKSTETTSKAQTDTLTQM 96

Query: 712 ITLTKESKPS-GNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSP 770
           +T T  S PS  N++        T   P+S  +   + +    MT     +  + +  S 
Sbjct: 97  MTSTLFSSPSVHNVMETAPPDEMTTSFPSSVTNTLMMTSKTITMTTSTDSTLGNTEETST 156

Query: 771 GLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSP 830
               S  P  SA+ +          T         +  T   ++ ASS +    +   + 
Sbjct: 157 AGTESSTPVTSAVSITAGQEGQSRTT---------SWRTSIQDTSASSQNHWTRSTQTTR 207

Query: 831 KSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIY 890
           +S   T T+  TS  S    +H + G   +++    +T    +    +  ++ S  +++ 
Sbjct: 208 ESQTSTLTHRTTSTPSFSPSVHNVTGTVSQKTSPSGETATSSLCSVTNTSMMTSEKITVT 267

Query: 891 PSSAEVL 897
            S+   L
Sbjct: 268 TSTGSTL 274



 Score = 32.0 bits (71), Expect = 4.3
 Identities = 75/347 (21%), Positives = 122/347 (35%), Gaps = 38/347 (10%)

Query: 512  PTGVAQVRSTGIPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGP 571
            P  V    S    +  +   ++P+ + +G    L +T   S S         GQ  +   
Sbjct: 1216 PLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSAST--------GQATSLLV 1267

Query: 572  FSAGHVPCSTSRTLGSTDTILIGNNHIT-------GSGSNGNVPYLQRNALTLPHNRTNL 624
                 V    +  L  T T      H+T        S S G+   L   +L+       +
Sbjct: 1268 TDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTM 1327

Query: 625  TSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPT 684
                  P      ++T       SS S G     PL  T  S    +A +G        +
Sbjct: 1328 PLPVTSPSSASTGDTTPLPVTDASSVSTGHT--TPLHVTDAS----SASTGQATPLPVTS 1381

Query: 685  LPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPS-GNILTVPETSRHTGETPNSTAS 743
            L S S      L   S  +A++G    + +T  S  S G+   +P T   +  T ++T+ 
Sbjct: 1382 LSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATS- 1440

Query: 744  VEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNI 803
               LP     +T  +  S  H         SS +   +  L+    ++V TG      + 
Sbjct: 1441 ---LP-----VTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTG------DT 1486

Query: 804  HPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSG 850
             P   T T +S ++   + +   +PS  ST   T   VTSL+S  +G
Sbjct: 1487 TPLPVTST-SSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTG 1532



 Score = 32.0 bits (71), Expect = 4.3
 Identities = 84/386 (21%), Positives = 136/386 (35%), Gaps = 50/386 (12%)

Query: 508  HQMRPTGVAQVRSTGIPNGPTADSS------LPTNSVS----GQQPQLALTRVPSVSQPG 557
            H   P+  +   +T +P   T+ +S      LP  S+S    G    L +T   S S   
Sbjct: 2930 HVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSLSSVSTGDTTPLPVTSPSSASTGH 2989

Query: 558  VRP--ACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNAL 615
              P         + G  +A  V  ++S + G T  + + +   T S S G    L   +L
Sbjct: 2990 TTPLPVTDTSSASTGQATALPVTSTSSASTGDTTPLPVTD---TSSASTGQATPLPVTSL 3046

Query: 616  TLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPLSS-----TGPSQHLQ 670
            +              P      ++T  L    SS S G     P++S     TG +  L 
Sbjct: 3047 SSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVSTGDTTPLP 3106

Query: 671  AAGSGIQNQNGHPTLP-----SNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNIL 725
                   +     +LP     S S     +L    + +A +G    + +T  S  S    
Sbjct: 3107 VTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTGDT 3166

Query: 726  T---VPETSR-HTGE------TPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSS 775
            T   V ETS   TG       T  S+AS      H   +   +  S S GD+    +  +
Sbjct: 3167 TPLLVTETSSVSTGHATPLLVTDASSAST----GHATPLHVTSPSSASTGDTTPVPVTDT 3222

Query: 776  DNPQLSAL----LMGKANNNVGTGTCDKVNNIHPA-------VHTKTDNSVASSPSSAIS 824
             +          + G ++ + G  T   V +I  A       +     +SV++  +  + 
Sbjct: 3223 SSVSTGHATPLPVTGLSSASTGDTTRLPVTDISSASTGQATPLPVTNTSSVSTGDTMPLP 3282

Query: 825  TATPSPKSTEQTTTNSVTSLNSPHSG 850
              +PS  ST   T   VTS +S  +G
Sbjct: 3283 VTSPSSASTGHATPLPVTSTSSASTG 3308



 Score = 31.2 bits (69), Expect = 7.3
 Identities = 73/377 (19%), Positives = 142/377 (37%), Gaps = 37/377 (9%)

Query: 506  QQHQMRPTGVAQVRSTG-IPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPG 564
            + H + P+G  +  +T  I N      +  +++ +G    L +T   SVS     P    
Sbjct: 953  ETHTLSPSGSGKTFTTALISNATPLPVTYASSASTGHTTPLHVTDASSVSTGHATPLPVT 1012

Query: 565  QPLANGPFSAGH-----VPCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPH 619
             P +    S GH     V  ++S + G    + + +     +G +  +P    ++ +  H
Sbjct: 1013 SPSS---VSTGHTTPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPLPVTDTSSASTGH 1069

Query: 620  NR----TNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSG 675
                  T+L+S++           T     G ++    P  +    STG +  L    + 
Sbjct: 1070 VTPLPVTSLSSASTGDTTPLPVTDTSSASTGHATSL--PVTDTSSVSTGHTTPLPVTDTS 1127

Query: 676  IQNQNGHPTLP---SNSVTQG--AALNHLSSHTATSGGQQGITLTKESKPS-GNILTVPE 729
              +     +LP   ++SV+ G    L+   + +A++G    + +T  S  S G+   +P 
Sbjct: 1128 SASTGHATSLPVTDTSSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPV 1187

Query: 730  TSRHTGETPNSTASV-----EGLPNHVHQMTADAVCSPSHGDSKS-----PGLLSSDNP- 778
            TS  +  T ++T  +          H   +      S S   + S     P   S+ +  
Sbjct: 1188 TSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTT 1247

Query: 779  -----QLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKST 833
                   S+   G+A + + T T          +   + +S ++   + +   +PS  ST
Sbjct: 1248 PLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSAST 1307

Query: 834  EQTTTNSVTSLNSPHSG 850
               T   VTSL+S  +G
Sbjct: 1308 GHATPLPVTSLSSASTG 1324


>gi|20143482 melanoma antigen family E, 1 [Homo sapiens]
          Length = 957

 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 88/379 (23%), Positives = 139/379 (36%), Gaps = 47/379 (12%)

Query: 516 AQVRSTGIPNGPTADSSL--------PTNSVSGQQPQLALTRVP-SVSQPGVRPACPGQP 566
           A V  + +P GP+    L        P+ SV     +   T VP ++S+     +  GQP
Sbjct: 38  ADVPGSDVPQGPSDSQILQGLCASEGPSTSVLPTSAEGPSTFVPPTISEAS---SASGQP 94

Query: 567 -LANGPFSAGHVPCSTSRTLGSTDTILIGN-NHITGSGSNGNVPYLQRNALTLPHNRTNL 624
            ++ GP ++     S   +     TI  G    +T + S G              N +  
Sbjct: 95  TISEGPGTSVLPTPSEGLSTSGPPTISKGLCTSVTLAASEGR-------------NTSRP 141

Query: 625 TSSAEEPWKNQLSNSTQGLHKGQSSHSAGPN-GERPLSSTGPSQHLQAAGSGIQNQNGHP 683
            +S+EEP     S S         S S  P  GE   +S  P+ +   + S +   +  P
Sbjct: 142 PTSSEEP-----STSVPPTASEVPSTSLPPTPGEGTSTSVPPTAYEGPSTSVVPTPDEGP 196

Query: 684 TLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTAS 743
           +  S   T G          AT G    +  T +  PS    +VP T+     TP     
Sbjct: 197 ST-SVLPTPGEGPGTSVPLAATEGLSTSVQATPDEGPS---TSVPPTATEGLSTPVPPTR 252

Query: 744 VEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQLSALLM---GKANNNVGTGTCDKV 800
            EG    V         +P  G S S    +SD   +S +     G + +   T T    
Sbjct: 253 DEGPSTSVP-------ATPGEGPSTSVLPAASDGQSISLVPTRGKGSSTSVPPTATEGLS 305

Query: 801 NNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGME 860
            ++ P     +  SV  +P   +ST+ P   + E +T+   T    P + +  I GEG+ 
Sbjct: 306 TSVQPTAGEGSSTSVPPTPGGGLSTSVPPTATEELSTSVPPTPGEGPSTSVLPIPGEGLS 365

Query: 861 ESQSPMKTDLLLVNHKPSP 879
            S  P  +D    +  P+P
Sbjct: 366 TSVPPTASDGSDTSVPPTP 384



 Score = 38.9 bits (89), Expect = 0.035
 Identities = 36/137 (26%), Positives = 52/137 (37%), Gaps = 5/137 (3%)

Query: 805 PAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQS 864
           P +      SV  + S   +T+ P   S E +T+   T+   P + L    GEG   S  
Sbjct: 118 PTISKGLCTSVTLAASEGRNTSRPPTSSEEPSTSVPPTASEVPSTSLPPTPGEGTSTSVP 177

Query: 865 PMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRPP 924
           P   +    +  P+P   PS SV   P       +       GLS S     +  P   P
Sbjct: 178 PTAYEGPSTSVVPTPDEGPSTSVLPTPGEGPG-TSVPLAATEGLSTSV----QATPDEGP 232

Query: 925 SSPYPPLPKDKLNPPTP 941
           S+  PP   + L+ P P
Sbjct: 233 STSVPPTATEGLSTPVP 249


>gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]
          Length = 861

 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 76/369 (20%), Positives = 136/369 (36%), Gaps = 43/369 (11%)

Query: 495 LEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSGQQPQLALTRVPSVS 554
           L +  + F    +   R    A+  S+G+    T   S P  + +   P    T +P VS
Sbjct: 132 LSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDS--TTMPGVS 189

Query: 555 QPGVRP-ACPGQ------PLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITGSGSNGNV 607
           Q      + PG       P    P S G    +   + G T T  + +N  T      + 
Sbjct: 190 QESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEAST 249

Query: 608 PYLQRNALTLPHNRTNLTSSAE--------EPWKNQL------SNSTQGLHKGQSSHSAG 653
           P    ++   PH   + +SS          + W +        S +T    K  +++ + 
Sbjct: 250 PV--HSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSS 307

Query: 654 PNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGIT 713
           P       S+ P+ H  A+ + + +     + P +S     A     + +ATSG  +  T
Sbjct: 308 P-------SSTPTTHFSASSTTLGHSE--ESTPVHSSPVATATTPPPARSATSGHVEEST 358

Query: 714 LTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSP-GL 772
               S  S   +  PE+S  +G +  S A+  G   H    T     + +H    S  G 
Sbjct: 359 AYHRSPGSTQTMHFPESSTTSGHSEES-ATFHGSTTHTKSSTPSTTAALAHTSYHSSLGS 417

Query: 773 LSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKS 832
             + + + S+ + G++  +       K ++  P     T     S+PS  +  +TPSP S
Sbjct: 418 TETTHFRDSSTISGRSEES-------KASHSSPDAMATTVLPAGSTPSVLVGDSTPSPIS 470

Query: 833 TEQTTTNSV 841
           +    T ++
Sbjct: 471 SGSMETTAL 479



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 76/352 (21%), Positives = 129/352 (36%), Gaps = 35/352 (9%)

Query: 516 AQVRSTGIPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRP-ACPGQPLANGPFSA 574
           A++ S+G+    T   S P ++ +   P    T +P +SQ      + PG          
Sbjct: 509 ARMTSSGVSEESTTSHSRPGSTHTTAFP--GSTTMPGLSQESTASHSSPG---------- 556

Query: 575 GHVPCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKN 634
              P  T+ + GST    +G  + T   S G+          LP N T   +S       
Sbjct: 557 ---PTDTTLSPGSTTASSLGPEYTTFHSSPGST-----ETTLLPDNTT---ASGLLEAST 605

Query: 635 QLSNSTQGLHKGQS-SHSAGPNGERPLSSTGPS-QHLQAAGSGIQNQNGHPTLPSNSVTQ 692
            + +ST+  H   S + S    GE     + PS +  + A     +    P+  S+    
Sbjct: 606 PVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPS 665

Query: 693 GAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVH 752
                H+S+ + TSG  +  T    S  S   +  PE+   +G    ST S     + + 
Sbjct: 666 SIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTIS 725

Query: 753 Q--MTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGT-GTCDKVNNIHPAVHT 809
               T  A+         SPG  ++ +   S+   G++  +  +  + D    I     +
Sbjct: 726 SAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARS 785

Query: 810 KTDNSVASSPSSAIS------TATPSPKSTEQTTTNSVTSLNSPHSGLHTIN 855
                +  S +S IS      TA P   +T   +  S T  +SP S   T++
Sbjct: 786 TNSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLS 837


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 76/369 (20%), Positives = 136/369 (36%), Gaps = 43/369 (11%)

Query: 495 LEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSGQQPQLALTRVPSVS 554
           L +  + F    +   R    A+  S+G+    T   S P  + +   P    T +P VS
Sbjct: 276 LSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDS--TTMPGVS 333

Query: 555 QPGVRP-ACPGQ------PLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITGSGSNGNV 607
           Q      + PG       P    P S G    +   + G T T  + +N  T      + 
Sbjct: 334 QESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEAST 393

Query: 608 PYLQRNALTLPHNRTNLTSSAE--------EPWKNQL------SNSTQGLHKGQSSHSAG 653
           P    ++   PH   + +SS          + W +        S +T    K  +++ + 
Sbjct: 394 PV--HSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSS 451

Query: 654 PNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGIT 713
           P       S+ P+ H  A+ + + +     + P +S     A     + +ATSG  +  T
Sbjct: 452 P-------SSTPTTHFSASSTTLGHSE--ESTPVHSSPVATATTPPPARSATSGHVEEST 502

Query: 714 LTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSP-GL 772
               S  S   +  PE+S  +G +  S A+  G   H    T     + +H    S  G 
Sbjct: 503 AYHRSPGSTQTMHFPESSTTSGHSEES-ATFHGSTTHTKSSTPSTTAALAHTSYHSSLGS 561

Query: 773 LSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKS 832
             + + + S+ + G++  +       K ++  P     T     S+PS  +  +TPSP S
Sbjct: 562 TETTHFRDSSTISGRSEES-------KASHSSPDAMATTVLPAGSTPSVLVGDSTPSPIS 614

Query: 833 TEQTTTNSV 841
           +    T ++
Sbjct: 615 SGSMETTAL 623



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 103/464 (22%), Positives = 165/464 (35%), Gaps = 61/464 (13%)

Query: 520  STGIPNGPTA----DSSLPTNSVSGQQPQLALTRVPSVSQ----------PGVRPACPGQ 565
            +T +P+  TA    ++S P +S +G  P   L+   S ++          P  +   P  
Sbjct: 1787 TTLLPDNTTASGLLEASTPVHSSTGS-PHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAP 1845

Query: 566  PLANGPF-----SAGHVPCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHN 620
            P     F     ++   P ST  T  S  +  +G +  + +  +  V      A T    
Sbjct: 1846 PTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVA----TATTPSPA 1901

Query: 621  RTNLTSSAEEPWKNQLS-NSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQ 679
            R+  +   EE      S  STQ +H  +SS ++G + E   S +  +  + +  S     
Sbjct: 1902 RSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSAL 1961

Query: 680  NGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPE---TSRHTGE 736
               PT   +S     A  H    + TSG  +  T +  S+ +   + +P    TS   GE
Sbjct: 1962 VEEPT-SYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGE 2020

Query: 737  T---PNSTASVE--GLPNHVHQMTADAVCSPSHGDSKSPGLL-------SSDNPQLSALL 784
            +   P S+ S+E   LP            +  H   +SP          SS   + S   
Sbjct: 2021 STTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTS 2080

Query: 785  MGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSL 844
              +  +   T   D       + H+ T +S   SP S  +T  P+  +T   +  S TS 
Sbjct: 2081 HSRPGSTHTTAFPDSTTTPGLSRHSTTSHS---SPGSTDTTLLPASTTTSGPSQESTTSH 2137

Query: 845  NSPHS-------GLHTINGEGMEES---QSPMKTDLLLVNHKPSPQIIPSMSVSIYPS-- 892
            +SP S       G  T    G E +    SP  T   L     +   I   S  ++ S  
Sbjct: 2138 SSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTG 2197

Query: 893  SAEVLKACRNLGKNGLSNSSILLDKCP-----PPRPPSSPYPPL 931
            S     +  +    GL   S      P      P PPS+   P+
Sbjct: 2198 SPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPV 2241



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 79/363 (21%), Positives = 133/363 (36%), Gaps = 54/363 (14%)

Query: 513  TGVAQVRSTGIPNGPTA----DSSLPTNSVSGQQPQLALTRVPSVSQ----------PGV 558
            +G     +T +P+  TA    ++S P +S +G  P   L+   S ++          P  
Sbjct: 3337 SGPGSTETTLLPDNTTASGLLEASTPVHSSTGS-PHTTLSPAGSTTRQGESTTFQSWPNS 3395

Query: 559  RPACPGQPLANGPF-----SAGHVPCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRN 613
            +   P  P     F     ++   P ST  T  S  +  +G +  + +  +  V      
Sbjct: 3396 KDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVA----- 3450

Query: 614  ALTLPHNRTNLTSSAEEPWKNQLSN--STQGLHKGQSSHSAGPNGERPLSSTGPSQHLQA 671
              T P    + TS   E      S+  STQ +H  +S  ++G   E   S +  +  + +
Sbjct: 3451 TATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISS 3510

Query: 672  AGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETS 731
            A S        PT   +S     A  H    + TSG  +  T +  S+ +   + +P  S
Sbjct: 3511 APSTTSALVEEPT-SYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARS 3569

Query: 732  RHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSD-----NPQLSALLMG 786
              +     ST S    P     M   A+     G + +PGL         +P+  A  + 
Sbjct: 3570 TTSVLLGESTTS----PISSGSMETTAL----PGSTTTPGLSEKSTTFHSSPRSPATTLS 3621

Query: 787  KANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSLNS 846
             A+    +G  ++    H            S P S  +TA P   +T   + +S TS +S
Sbjct: 3622 PASTT-SSGVSEESTTSH------------SRPGSTHTTAFPDSTTTPGLSRHSTTSHSS 3668

Query: 847  PHS 849
            P S
Sbjct: 3669 PGS 3671



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 89/390 (22%), Positives = 133/390 (34%), Gaps = 75/390 (19%)

Query: 524  PNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSR 583
            P  P A  S  T + SG   + + +     SQPG             P  + H   S S 
Sbjct: 2530 PRSPDATLSPATTTSSGVSEESSTSH----SQPGSTHTTAFPDSTTTPGLSRHSTTSHSS 2585

Query: 584  TLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGL 643
              GSTDT L+  +  T   S  +         T  H+    T +A  P       ST  L
Sbjct: 2586 P-GSTDTTLLPASTTTSGPSQES---------TTSHSSPGSTDTALSP------GSTTAL 2629

Query: 644  HKGQSS----HSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHL 699
              GQ S     S G         +  S  +  A + + +  G P               L
Sbjct: 2630 SFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTT------------L 2677

Query: 700  SSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAV 759
            S  ++TS G QG + T ++ P+         S HT  +P STA+              A 
Sbjct: 2678 SPASSTSPGLQGESTTFQTHPA---------STHTTPSPPSTAT--------------AP 2714

Query: 760  CSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPA-VHTKTDNSVAS- 817
               S    +SPG   + +   S+   G +  +    +    +   P+  H+ T     S 
Sbjct: 2715 VEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGEST 2774

Query: 818  ----SPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTIN-------GEGMEESQSPM 866
                SP S   T  P   +T   +  S T  +SP S   T++       G G E + S  
Sbjct: 2775 TSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRS 2834

Query: 867  KTDLLLVNHKPSPQIIPSM---SVSIYPSS 893
            +         P+    P +   S ++Y SS
Sbjct: 2835 QPGSTHSTVSPASTTTPGLSEESTTVYSSS 2864



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 74/332 (22%), Positives = 121/332 (36%), Gaps = 36/332 (10%)

Query: 526  GPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCST--SR 583
            G T  + LP N+ +    + ++    S   P    +  G     G  +  H   S+  +R
Sbjct: 728  GSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTR 787

Query: 584  TLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLS-NSTQG 642
                T T        T  GS  ++P    +A      R+  +   EE      S  STQ 
Sbjct: 788  PAPPTTTSAFVEPSTTSHGSPSSIPTTHISA------RSTTSGLVEESTTYHSSPGSTQT 841

Query: 643  LHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSH 702
            +H  +S  ++G   E   S +  +  + +A S        PT   +S     A  H    
Sbjct: 842  MHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPT-SYHSSPGSTATTHFPDS 900

Query: 703  TATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSP 762
            + TSG  +  T +  S+ +   + +P           ST SV      + + T   + S 
Sbjct: 901  STTSGRSEESTASHSSQDATGTIVLPA---------RSTTSVL-----LGESTTSPISSG 946

Query: 763  SHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASS---- 818
            S   +  PG  S+  P LS     + +    +        + PA  T +  S  S+    
Sbjct: 947  SMETTALPG--STTTPGLS-----ERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRS 999

Query: 819  -PSSAISTATPSPKSTEQTTTNSVTSLNSPHS 849
             P S  +TA P   +T   + +S TS +SP S
Sbjct: 1000 RPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGS 1031



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 76/352 (21%), Positives = 128/352 (36%), Gaps = 35/352 (9%)

Query: 516 AQVRSTGIPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRP-ACPGQPLANGPFSA 574
           A + S+G+    T   S P ++ +   P    T +P +SQ      + PG          
Sbjct: 653 ASMTSSGVSEESTTSHSRPGSTHTTAFP--GSTTMPGLSQESTASHSSPG---------- 700

Query: 575 GHVPCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKN 634
              P  T+ + GST    +G  + T     G+          LP N T   +S       
Sbjct: 701 ---PTDTTLSPGSTTASSLGPEYTTFHSRPGST-----ETTLLPDNTT---ASGLLEASM 749

Query: 635 QLSNSTQGLHKGQS-SHSAGPNGERPLSSTGPS-QHLQAAGSGIQNQNGHPTLPSNSVTQ 692
            + +ST+  H   S + S    GE     + PS +  + A     +    P+  S+    
Sbjct: 750 PVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPS 809

Query: 693 GAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVH 752
                H+S+ + TSG  +  T    S  S   +  PE+   +G    ST S     + + 
Sbjct: 810 SIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTIS 869

Query: 753 Q--MTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGT-GTCDKVNNIHPAVHT 809
               T  A+         SPG  ++ +   S+   G++  +  +  + D    I     +
Sbjct: 870 SAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARS 929

Query: 810 KTDNSVASSPSSAIS------TATPSPKSTEQTTTNSVTSLNSPHSGLHTIN 855
            T   +  S +S IS      TA P   +T   +  S T  +SP S   T++
Sbjct: 930 TTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLS 981



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 73/330 (22%), Positives = 116/330 (35%), Gaps = 54/330 (16%)

Query: 594  GNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAG 653
            G+ H T    +   P L R++ T  H+    T +   P     S S+Q      SS  + 
Sbjct: 3642 GSTHTTAFPDSTTTPGLSRHSTT-SHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGST 3700

Query: 654  PNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQ--------------GAALNHL 699
                 P S+T  S   ++        + H TL  +S T               G+    L
Sbjct: 3701 DTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL 3760

Query: 700  SSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAV 759
            S  ++TS G QG +   ++ P+         S HT  +P STA+              A 
Sbjct: 3761 SPASSTSPGLQGESTAFQTHPA---------STHTTPSPPSTAT--------------AP 3797

Query: 760  CSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPA-VHTKTDNSVAS- 817
               S    +SPG   + +   S+   G +  +    +    +   P+  H+ T     S 
Sbjct: 3798 VEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGEST 3857

Query: 818  ----SPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTIN-------GEGMEESQSPM 866
                SP S   T  P   +T   +  S T  +SP S   T++       G G E + S  
Sbjct: 3858 TSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRS 3917

Query: 867  KTDLLLVNHKPSPQIIPSM---SVSIYPSS 893
            +         P+    P +   S ++Y SS
Sbjct: 3918 QPGSTHSTVSPASTTTPGLSEESTTVYSSS 3947



 Score = 39.7 bits (91), Expect = 0.021
 Identities = 88/446 (19%), Positives = 150/446 (33%), Gaps = 76/446 (17%)

Query: 478  EQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNS 537
            E+  A+ ++ +    ++L    +  VL+ +    P     + +T +P   T       ++
Sbjct: 908  EESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERST 967

Query: 538  VSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNH 597
                 P+   T +   S                  S      +TSR+         G+ H
Sbjct: 968  TFHSSPRSPATTLSPASTTS---------------SGVSEESTTSRSRP-------GSTH 1005

Query: 598  ITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGE 657
             T    +   P L R++ T  H+    T +   P     S  +Q      SS  +     
Sbjct: 1006 TTAFPDSTTTPGLSRHSTT-SHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTAL 1064

Query: 658  RPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQ--------------GAALNHLSSHT 703
             P S+T  S   ++        + H TL  +S T               G+    LS  +
Sbjct: 1065 SPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPAS 1124

Query: 704  ATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPS 763
            +TS G QG +   ++ P+         S HT  +P STA+              A    S
Sbjct: 1125 STSPGLQGESTAFQTHPA---------STHTTPSPPSTAT--------------APVEES 1161

Query: 764  HGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPA-VHTKTDNSVAS----- 817
                +SPG   + +   S+   G +  +    +    +   P+  H+ T     S     
Sbjct: 1162 TTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRI 1221

Query: 818  SPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTIN-------GEGMEESQSPMKTDL 870
            SP S   T  P   +T   +  S T  +SP S   T++       G G E + S  +   
Sbjct: 1222 SPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGS 1281

Query: 871  LLVNHKPSPQIIPSM---SVSIYPSS 893
                  P+    P +   S ++Y SS
Sbjct: 1282 THSTVSPASTTTPGLSEESTTVYSSS 1307



 Score = 39.3 bits (90), Expect = 0.027
 Identities = 92/451 (20%), Positives = 150/451 (33%), Gaps = 86/451 (19%)

Query: 478  EQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNS 537
            E+  A+ ++ +    ++L    +  VL+ +    P     + +T +P   T       ++
Sbjct: 1991 EESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKST 2050

Query: 538  VSGQQPQLALTRVP---------------SVSQPGVRPACPGQPLANGPFSAGHVPCSTS 582
                 P+   T +                S S+PG             P  + H   S S
Sbjct: 2051 TFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHS 2110

Query: 583  RTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQG 642
               GSTDT L+  +  T   S  +         T  H+    T +A  P       ST  
Sbjct: 2111 SP-GSTDTTLLPASTTTSGPSQES---------TTSHSSPGSTDTALSP------GSTTA 2154

Query: 643  LHKGQSS----HSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNH 698
            L  GQ S     S G         +  S  +  A + + +  G P               
Sbjct: 2155 LSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTT------------ 2202

Query: 699  LSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADA 758
            LS  ++TS G QG +   ++ P+         S HT  +P STA+              A
Sbjct: 2203 LSPASSTSPGLQGESTAFQTHPA---------STHTTPSPPSTAT--------------A 2239

Query: 759  VCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPA-VHTKTDNSVAS 817
                S    +SPG   + +   S+   G +  +    +    +   P+  H+ T     S
Sbjct: 2240 PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES 2299

Query: 818  -----SPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTIN-------GEGMEESQSP 865
                 SP S   T  P   +T   +  S T  +SP S   T++       G G E + S 
Sbjct: 2300 TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSR 2359

Query: 866  MKTDLLLVNHKPSPQIIPSM---SVSIYPSS 893
             +         P+    P +   S ++Y SS
Sbjct: 2360 SQPGSTHSTVSPASTTTPGLSEESTTVYSSS 2390



 Score = 37.7 bits (86), Expect = 0.078
 Identities = 61/298 (20%), Positives = 107/298 (35%), Gaps = 20/298 (6%)

Query: 578  PCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLS 637
            P ++  + GST+T  +  +  T   S  +  +        P +     S A         
Sbjct: 4303 PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSS-----PRSPDTTLSPASTTSSGVSE 4357

Query: 638  NSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALN 697
             ST    +  S H+       P S+T P    ++  S     +   TL   S T  ++L 
Sbjct: 4358 ESTTSHSRPGSMHTTA----FPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTT-ASSLG 4412

Query: 698  HLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTAD 757
              S+   +S G    TL  ++  +  +L        +  +P++T S  G      + T  
Sbjct: 4413 PESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTF 4472

Query: 758  AVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVAS 817
                 S   + +P   +S   +LS    G  ++   T        +  +  + T   V S
Sbjct: 4473 QSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTT---VHS 4529

Query: 818  SPSSAISTATPSPKSTEQTTTNSVTSLNSPHS-------GLHTINGEGMEESQSPMKT 868
            SP +  +T +P+  +T      S T  +SP S         +T +G G E + S   T
Sbjct: 4530 SPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSST 4587



 Score = 37.4 bits (85), Expect = 0.10
 Identities = 94/425 (22%), Positives = 146/425 (34%), Gaps = 60/425 (14%)

Query: 524  PNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSR 583
            P  PT   S  + +  G   +   +R    SQPG   +         P  +       S 
Sbjct: 2334 PRSPTTTLSPASMTSLGVGEESTTSR----SQPGSTHSTVSPASTTTPGLSEESTTVYSS 2389

Query: 584  TLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGL 643
            + GST+T +      T         +  R A       T+ T   E+       ++T GL
Sbjct: 2390 SPGSTETTVFPRTPTTSVRGEEPTTFHSRPA------STHTTLFTED-------STTSGL 2436

Query: 644  HKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHT 703
             +  ++    P      + TG    L  A  G ++     T PS+S + G  L+   + +
Sbjct: 2437 TEESTAFPGSPAS----TQTGLPATLTTADLGEEST----TFPSSSGSTGTTLS--PARS 2486

Query: 704  ATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPS 763
             TSG      L  ES PS    +  ET+   G     + S +    +    + DA  SP+
Sbjct: 2487 TTSG------LVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPA 2540

Query: 764  HGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAI 823
                      SS   + S+    +  +   T   D       + H+ T +S   SP S  
Sbjct: 2541 T-------TTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHS---SPGSTD 2590

Query: 824  STATPSPKSTEQTTTNSVTSLNSPHS-------GLHTINGEGMEES---QSPMKTDLLLV 873
            +T  P+  +T   +  S TS +SP S       G  T    G E +    SP  T   L 
Sbjct: 2591 TTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLF 2650

Query: 874  NHKPSPQIIPSMSVSIYPS--SAEVLKACRNLGKNGLSNSSILLDKCP-----PPRPPSS 926
                +   I   S  ++ S  S     +  +    GL   S      P      P PPS+
Sbjct: 2651 PDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPST 2710

Query: 927  PYPPL 931
               P+
Sbjct: 2711 ATAPV 2715



 Score = 37.4 bits (85), Expect = 0.10
 Identities = 83/355 (23%), Positives = 127/355 (35%), Gaps = 42/355 (11%)

Query: 520  STGIPNGPTADSSLPTNSVSGQ----QPQLALTRV-PSVSQPGVRPACPGQPLANGPFSA 574
            STG P    + +S  +  + G+    Q   A T   PS       P          P S 
Sbjct: 2669 STGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGST 2728

Query: 575  G--HVPCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPW 632
               H P S S T G ++   I ++    SG+  +      +A +    R   T+S   P 
Sbjct: 2729 PTTHFPAS-STTSGHSEKSTIFHSSPDASGTTPS------SAHSTTSGRGESTTSRISPG 2781

Query: 633  KNQL-----SNSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPS 687
              ++     S +T GL +  ++  + P    P ++  P+  + + G G ++        S
Sbjct: 2782 STEITTLPGSTTTPGLSEASTTFYSSPRS--PTTTLSPAS-MTSLGVGEESTTSRSQPGS 2838

Query: 688  NSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHT---GETPNSTASV 744
               T   A       T T G  +  T    S P     TV   S  T   GE P +  S 
Sbjct: 2839 THSTVSPA------STTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHS- 2891

Query: 745  EGLPNHVHQMTADAVCSPSHGDSKS-PGLLSSDNPQLSALL----MGKANNNVGTGTCDK 799
                 H    T D+  S    +S + PG  +S    L A L    +G+ +    + +   
Sbjct: 2892 RPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGST 2951

Query: 800  VNNIHPAVHTKTD---NSVAS--SPSSAISTATPSPKSTEQTTTNSVTSLNSPHS 849
               + PA  T +     S  S  SPSS  +T  P   +T   +  S T   SP S
Sbjct: 2952 GTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRS 3006



 Score = 36.6 bits (83), Expect = 0.17
 Identities = 80/354 (22%), Positives = 124/354 (35%), Gaps = 40/354 (11%)

Query: 520  STGIPNGPTADSSLPTNSVSGQ----QPQLALTRV-PSVSQPGVRPACPGQPLANGPFSA 574
            STG P    + +S  +  + G+    Q   A T   PS       P          P S 
Sbjct: 3752 STGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGST 3811

Query: 575  G--HVPCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPW 632
               H P S S T G ++   I ++    SG+  +      +A +    R   T+S   P 
Sbjct: 3812 PTTHFPAS-STTSGHSEKSTIFHSSPDASGTTPS------SAHSTTSGRGESTTSRISPG 3864

Query: 633  KNQL-----SNSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPS 687
              ++     S +T GL +  ++  + P    P ++  P+  + + G G ++        S
Sbjct: 3865 STEITTLPGSTTTPGLSEASTTFYSSPRS--PTTTLSPAS-MTSLGVGEESTTSRSQPGS 3921

Query: 688  NSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGL 747
               T   A       T T G  +  T    S P     TV   S  T        +    
Sbjct: 3922 THSTVSPA------STTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSR 3975

Query: 748  PNHVHQ--MTADAVCSPSHGDSKS-PGLLSSDNPQLSALL----MGKANNNVGTGTCDKV 800
            P   H    T D+  S    +S + PG  +S    L A L    +G+ +    + +    
Sbjct: 3976 PASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTG 4035

Query: 801  NNIHPAVHTKTD---NSVAS--SPSSAISTATPSPKSTEQTTTNSVTSLNSPHS 849
              + PA  T +     S  S  SPSS  +T  P   +T   +  S T   SP S
Sbjct: 4036 TKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRS 4089



 Score = 35.8 bits (81), Expect = 0.30
 Identities = 82/355 (23%), Positives = 129/355 (36%), Gaps = 42/355 (11%)

Query: 520  STGIPNGPTADSSLPTNSVSGQ----QPQLALTRV-PSVSQPGVRPACPGQPLANGPFSA 574
            STG P    + +S  +  + G+    Q   A T   PS       P          P S 
Sbjct: 1112 STGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGST 1171

Query: 575  G--HVPCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPW 632
               H P S S T G ++   I ++    SG+  +      +A +    R   T+S   P 
Sbjct: 1172 PTTHFPAS-STTSGHSEKSTIFHSSPDASGTTPS------SAHSTTSGRGESTTSRISPG 1224

Query: 633  KNQL-----SNSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPS 687
              ++     S +T GL +  ++  + P    P ++  P+  + + G G ++        S
Sbjct: 1225 STEITTLPGSTTTPGLSEASTTFYSSPRS--PTTTLSPAS-MTSLGVGEESTTSRSQPGS 1281

Query: 688  NSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPE---TSRHTGETPNSTASV 744
               T   A     S T     ++  T+   S+ S      P    TS H GE P +  S 
Sbjct: 1282 THSTVSPA-----STTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVH-GEEPTTFHS- 1334

Query: 745  EGLPNHVHQMTADAVCSPSHGDSKS-PGLLSSDNPQLSALL----MGKANNNVGTGTCDK 799
                 H    T D+  S    +S + PG  +S    L A L    +G+ +    + +   
Sbjct: 1335 RPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGST 1394

Query: 800  VNNIHPAVHTKTD---NSVAS--SPSSAISTATPSPKSTEQTTTNSVTSLNSPHS 849
               + PA  T +     S  S  SPSS  +T  P   +T   +  S T   SP S
Sbjct: 1395 GTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRS 1449



 Score = 35.0 bits (79), Expect = 0.51
 Identities = 79/397 (19%), Positives = 138/397 (34%), Gaps = 50/397 (12%)

Query: 478  EQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPT--------- 528
            E+  A+ ++ +    ++L    +  VL+ +    P     + +T +P   T         
Sbjct: 4631 EESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKST 4690

Query: 529  ----ADSSLPTNSVSGQQPQLALTRVPSV--SQPGVRPACPGQPLANGPFSAGHVPCSTS 582
                + SS PT   S     L  +   +   S P      P    +    ++G V  ST+
Sbjct: 4691 TFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARST---TSGLVEESTA 4747

Query: 583  --RTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLS-NS 639
               + GST T+    +      S  +         T+    +  ++  EEP     S  S
Sbjct: 4748 YHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGS 4807

Query: 640  TQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHL 699
                H  +SS ++G + E   S + P            + NG   LP++  T G      
Sbjct: 4808 IATTHFPESSTTSGRSEESTASHSSP------------DTNGITPLPAHFTTSGRIAEST 4855

Query: 700  SSHTATSGGQQGITLTKESKPSG-----NILTVPETSRHTGETPNS--TASVEGLPNHVH 752
            + +   S G    TL   +   G      IL     S     +P S  ++S+ G P  ++
Sbjct: 4856 TFYI--SPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLY 4913

Query: 753  QMTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTD 812
                    +     + + GL      Q S     K  +   T T     +I  +   +  
Sbjct: 4914 SQAESTHTTAFPASTTTSGL-----SQESTTFHSKPGS---TETTLSPGSITTSSFAQEF 4965

Query: 813  NSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHS 849
             +  S P SA+ST +P+  +    +  S T  +SP S
Sbjct: 4966 TTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGS 5002



 Score = 32.3 bits (72), Expect = 3.3
 Identities = 83/377 (22%), Positives = 135/377 (35%), Gaps = 55/377 (14%)

Query: 513  TGVAQVRSTGIPN-GPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPAC--PGQPLAN 569
            +GV++  ST     G T  ++ P ++ +    Q   T   S S  G   A   PG   A+
Sbjct: 1462 SGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTT---SHSSQGSTEATLSPGSTTAS 1518

Query: 570  GPFSAGHVPCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAE 629
               S G    +   + G T+T L+ ++ IT      + P             T LT ++ 
Sbjct: 1519 ---SLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSL----HTTLTPASS 1571

Query: 630  EPWKNQLSNSTQGLHKGQSSHSAGPNG-------------ERPLSSTGPSQHLQAAGSGI 676
                 Q  ++T       S  +  P G              RP S+  P+ H  A+ + +
Sbjct: 1572 TSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSST--PTTHFSASSTTL 1629

Query: 677  QNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGE 736
                   T+ S+    G AL    S T+   G+     T     SG+     ET+   G 
Sbjct: 1630 GRSEESTTVHSSPGATGTALFPTRSATSVLVGEP----TTSPISSGST----ETTALPGS 1681

Query: 737  TPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNV--GT 794
            T  +  S +    +    + D   SP+   + S G+  S+    S    G  +     G+
Sbjct: 1682 TTTAGLSEKSTTFYSSPRSPDTTLSPA--STTSSGV--SEESTTSHSRPGSTHTTAFPGS 1737

Query: 795  GTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTI 854
             T   V+    A H        SSP S  +T +P   +       S T  +SP S   T+
Sbjct: 1738 TTMPGVSQESTASH--------SSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTL 1789

Query: 855  -----NGEGMEESQSPM 866
                    G+ E+ +P+
Sbjct: 1790 LPDNTTASGLLEASTPV 1806



 Score = 31.2 bits (69), Expect = 7.3
 Identities = 70/343 (20%), Positives = 122/343 (35%), Gaps = 32/343 (9%)

Query: 526  GPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTL 585
            G  A +  P +S +  + + +     S    G+ P      L     ++G +  ST+  +
Sbjct: 4806 GSIATTHFPESSTTSGRSEESTASHSSPDTNGITP------LPAHFTTSGRIAESTTFYI 4859

Query: 586  --GSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGL 643
              GS +T L       G  +   + Y    +     +  ++TSS+       L +  +  
Sbjct: 4860 SPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAEST 4919

Query: 644  HKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHT 703
            H      S   +G   LS    + H +   +         TL   S+T  +     +   
Sbjct: 4920 HTTAFPASTTTSG---LSQESTTFHSKPGST-------ETTLSPGSITTSS----FAQEF 4965

Query: 704  ATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPS 763
             T   Q G  L+  S  S  +  + E S     +P ST +     +H + M+  +  S  
Sbjct: 4966 TTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAF--SHSNTMSIHSQQSTP 5023

Query: 764  HGDSKSPGLLSSDNPQ-LSALLMGKANNNVGTGTCDKVNNIHPAVHTKTD-----NSVAS 817
              DS  PG   +  P  L+   +G+ +    + +        PA  T +D      +   
Sbjct: 5024 FPDS--PGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDLVGEPTTFYI 5081

Query: 818  SPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGME 860
            SPS   +T  P+  ST   T  S T   SP      ++ E +E
Sbjct: 5082 SPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLE 5124


>gi|167466177 cell division cycle protein 27 isoform 1 [Homo
           sapiens]
          Length = 830

 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 44/158 (27%), Positives = 75/158 (47%), Gaps = 13/158 (8%)

Query: 99  LGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLY 158
           LGH  +L E+  KAL+ ++    +   ++ NA   YGLG++Y+    F  A   FQ+ L 
Sbjct: 613 LGHEFVLTEELDKALACFRNAIRVNPRHY-NA--WYGLGMIYYKQEKFSLAEMHFQKALD 669

Query: 159 VDPSFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQ 218
           ++P   ++  +   +G++       E +L     A+V  +P    N   +FH A +    
Sbjct: 670 INP---QSSVLLCHIGVVQHALKKSEKALDTLNKAIV-IDP---KNPLCKFHRASVLFAN 722

Query: 219 RKYHSAKEAYEQLLQ---TENLSAQVKATVLQQLGWMH 253
            KY SA +  E+L Q    E+L   +   V ++LG  H
Sbjct: 723 EKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTH 760



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 53/261 (20%), Positives = 104/261 (39%), Gaps = 30/261 (11%)

Query: 122 LQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVNT 181
           L S ++     L  +G  YF  + +  A + F EV  ++       EI+     ++ +  
Sbjct: 497 LPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTT--LWHLQK 554

Query: 182 DYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQV 241
           D   S+    L  +D N     + E      + +  QR++  A + +++ +Q +   A  
Sbjct: 555 DVALSVLSKDLTDMDKN-----SPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYA-- 607

Query: 242 KATVLQQLGWMHHTVDLLGDK--ATKE-SYAIQYLQKSLEADPNSGQSWYFLGRCYSSIG 298
                       +   LLG +   T+E   A+   + ++  +P    +WY LG  Y    
Sbjct: 608 ------------YAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQE 655

Query: 299 KVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD------HGHA 352
           K   A + +++++D +  S+   C IGV+     +   AL     A+ +D        H 
Sbjct: 656 KFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHR 715

Query: 353 AAWMDLGTLYESCNQPQDAIK 373
           A+ +     Y+S  Q  + +K
Sbjct: 716 ASVLFANEKYKSALQELEELK 736



 Score = 37.4 bits (85), Expect = 0.10
 Identities = 19/69 (27%), Positives = 35/69 (50%)

Query: 312 DKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDA 371
           D  + S + WC+ G  +  Q +   A++ +  A+Q+D  +A A+  LG  +    +   A
Sbjct: 567 DMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKA 626

Query: 372 IKCYLNATR 380
           + C+ NA R
Sbjct: 627 LACFRNAIR 635


>gi|167466175 cell division cycle protein 27 isoform 2 [Homo
           sapiens]
          Length = 824

 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 44/158 (27%), Positives = 75/158 (47%), Gaps = 13/158 (8%)

Query: 99  LGHFNLLLEDYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLY 158
           LGH  +L E+  KAL+ ++    +   ++ NA   YGLG++Y+    F  A   FQ+ L 
Sbjct: 607 LGHEFVLTEELDKALACFRNAIRVNPRHY-NA--WYGLGMIYYKQEKFSLAEMHFQKALD 663

Query: 159 VDPSFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQ 218
           ++P   ++  +   +G++       E +L     A+V  +P    N   +FH A +    
Sbjct: 664 INP---QSSVLLCHIGVVQHALKKSEKALDTLNKAIV-IDP---KNPLCKFHRASVLFAN 716

Query: 219 RKYHSAKEAYEQLLQ---TENLSAQVKATVLQQLGWMH 253
            KY SA +  E+L Q    E+L   +   V ++LG  H
Sbjct: 717 EKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTH 754



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 53/261 (20%), Positives = 104/261 (39%), Gaps = 30/261 (11%)

Query: 122 LQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVNT 181
           L S ++     L  +G  YF  + +  A + F EV  ++       EI+     ++ +  
Sbjct: 491 LPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTT--LWHLQK 548

Query: 182 DYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQV 241
           D   S+    L  +D N     + E      + +  QR++  A + +++ +Q +   A  
Sbjct: 549 DVALSVLSKDLTDMDKN-----SPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYA-- 601

Query: 242 KATVLQQLGWMHHTVDLLGDK--ATKE-SYAIQYLQKSLEADPNSGQSWYFLGRCYSSIG 298
                       +   LLG +   T+E   A+   + ++  +P    +WY LG  Y    
Sbjct: 602 ------------YAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQE 649

Query: 299 KVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD------HGHA 352
           K   A + +++++D +  S+   C IGV+     +   AL     A+ +D        H 
Sbjct: 650 KFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHR 709

Query: 353 AAWMDLGTLYESCNQPQDAIK 373
           A+ +     Y+S  Q  + +K
Sbjct: 710 ASVLFANEKYKSALQELEELK 730



 Score = 37.4 bits (85), Expect = 0.10
 Identities = 19/69 (27%), Positives = 35/69 (50%)

Query: 312 DKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDA 371
           D  + S + WC+ G  +  Q +   A++ +  A+Q+D  +A A+  LG  +    +   A
Sbjct: 561 DMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKA 620

Query: 372 IKCYLNATR 380
           + C+ NA R
Sbjct: 621 LACFRNAIR 629


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 76/369 (20%), Positives = 135/369 (36%), Gaps = 43/369 (11%)

Query: 495 LEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSGQQPQLALTRVPSVS 554
           L +  + F    +   R    A+  S+G+    T   S P  + +   P    T +P VS
Sbjct: 197 LSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDS--TTMPGVS 254

Query: 555 QPGVRP-ACPGQ------PLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITGSGSNGNV 607
           Q      + PG       P    P S G    +   + G T T  + +N  T      + 
Sbjct: 255 QESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEAST 314

Query: 608 PYLQRNALTLPHNRTNLTSSAE--------EPWKNQL------SNSTQGLHKGQSSHSAG 653
           P    ++   PH   +  SS          + W +        S +T    K  +++ + 
Sbjct: 315 PV--HSSTGSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSS 372

Query: 654 PNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGIT 713
           P       S+ P+ H  A+ + + +     + P +S     A     + +ATSG  +  T
Sbjct: 373 P-------SSTPTTHFSASSTTLGHSE--ESTPVHSSPVATATTPPPARSATSGHVEEST 423

Query: 714 LTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSP-GL 772
               S  S   +  PE+S  +G +  S A+  G   H    T     + +H    S  G 
Sbjct: 424 AYHRSPGSTQTMHFPESSTTSGHSEES-ATFHGSTTHTKSSTPSTTAALAHTSYHSSLGS 482

Query: 773 LSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKS 832
             + + + S+ + G++  +       K ++  P     T     S+PS  +  +TPSP S
Sbjct: 483 TETTHFRDSSTISGRSEES-------KASHSSPDAMATTVLPAGSTPSVLVGDSTPSPIS 535

Query: 833 TEQTTTNSV 841
           +    T ++
Sbjct: 536 SGSMETTAL 544



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 73/340 (21%), Positives = 125/340 (36%), Gaps = 50/340 (14%)

Query: 520 STGIPNGPTA----DSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAG 575
           +T +P+  TA    ++S+P +S S + P   L+   S ++ G        P +N      
Sbjct: 653 TTLLPDNTTASGLLEASMPVHS-STRSPHTTLSPAGSTTRQGESTTFHSWPSSND----- 706

Query: 576 HVPCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQ 635
                 +R    T T        T  GS  ++P    +A      R+  +   EE     
Sbjct: 707 ------TRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISA------RSTTSGLVEESTTYH 754

Query: 636 LS-NSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGA 694
            S  STQ +H  +S  ++G   E   S +  +  + +A S        PT   +S     
Sbjct: 755 SSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPT-SYHSSPGST 813

Query: 695 ALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQM 754
           A  H    + TSG  +    +  S+ +   + +P  S       NS    E   + +   
Sbjct: 814 ATTHFPDSSTTSGRSEESIASHSSQDATGTIVLPARST------NSVLLGESTTSPISSG 867

Query: 755 TADAVCSPSHGDSKSPGLLSSD-----NPQLSALLMGKANNNVGTGTCDKVNNIHPAVHT 809
           + +    P  G + +PGL         +P+  A  +  A+    +G  ++    H     
Sbjct: 868 SMETTALP--GSTTTPGLSERSTTFHSSPRSPATTLSPASTT-SSGVSEESTTSH----- 919

Query: 810 KTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHS 849
                  S P S  +TA P   +T   + +S TS +SP S
Sbjct: 920 -------SRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGS 952



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 77/358 (21%), Positives = 126/358 (35%), Gaps = 47/358 (13%)

Query: 516 AQVRSTGIPNGPTADSSLP----TNSVSGQ--QPQLALTRVPSVSQPGVRPAC--PGQPL 567
           A + S+G+    T   S P    T +  G    P L+     S S PG       PG   
Sbjct: 574 ASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTT 633

Query: 568 ANGPFSAGHVPCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSS 627
           A+   S G    +     GST+T L+ +N         ++P          H+ T    +
Sbjct: 634 AS---SLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPV---------HSSTRSPHT 681

Query: 628 AEEPWKNQLSNSTQGLHKGQSSHS-AGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLP 686
              P     + ST    +  + HS    N  RP   T  S  ++            P+  
Sbjct: 682 TLSP-----AGSTTRQGESTTFHSWPSSNDTRPAPPTTTSAFVE------------PSTT 724

Query: 687 SNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEG 746
           S+         H+S+ + TSG  +  T    S  S   +  PE+   +G    ST S   
Sbjct: 725 SHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSS 784

Query: 747 LPNHVHQ--MTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGT-GTCDKVNNI 803
             + +     T  A+         SPG  ++ +   S+   G++  ++ +  + D    I
Sbjct: 785 TTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESIASHSSQDATGTI 844

Query: 804 HPAVHTKTDNSVASSPSSAIS------TATPSPKSTEQTTTNSVTSLNSPHSGLHTIN 855
                +     +  S +S IS      TA P   +T   +  S T  +SP S   T++
Sbjct: 845 VLPARSTNSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLS 902



 Score = 36.2 bits (82), Expect = 0.23
 Identities = 77/397 (19%), Positives = 134/397 (33%), Gaps = 67/397 (16%)

Query: 513  TGVAQVRSTGIPNGPTA----DSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLA 568
            +G     +T +P+  TA    ++S P +S +G  P+  L+   S ++ G        P +
Sbjct: 1087 SGPGSTETTLLPDNTTASGLLEASTPVHSSTGS-PRTTLSPAGSTTRQGESTTFQSWPSS 1145

Query: 569  NGPFSAGHVPCSTSRTLGSTD---TILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLT 625
                 A     S    L +T       I   H + S +     + +    T  H+     
Sbjct: 1146 KDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTT----FGRSEESTTVHSSPVAP 1201

Query: 626  SSAEEPWKNQLSN-------------STQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAA 672
            ++   P ++  S              STQ +H  +SS ++G + E   S +  +  + + 
Sbjct: 1202 ATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSP 1261

Query: 673  GSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSR 732
             S        PT   +S     A  H    + TSG  +  T +  S  +  I  +P    
Sbjct: 1262 PSTTSALVEEPT-SYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFT 1320

Query: 733  HTGETPNSTASVEGLPNHVHQMTADAVCSPS--------HGDSKSPGLLSSDNPQLSALL 784
             +G    ST      P  +    A    +P         +  S+SP    S     S+ +
Sbjct: 1321 TSGRIAESTTFYIS-PGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSI 1379

Query: 785  MGKANNNVGTG------------TCDKVNNIHPAVHTK-------------TDNSVA--- 816
             G+  +                 T   ++      H+K             T +S A   
Sbjct: 1380 SGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEF 1439

Query: 817  ----SSPSSAISTATPSPKSTEQTTTNSVTSLNSPHS 849
                S P SA+ST +P+  +    +  S T  +SP S
Sbjct: 1440 TTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGS 1476



 Score = 31.2 bits (69), Expect = 7.3
 Identities = 70/343 (20%), Positives = 122/343 (35%), Gaps = 32/343 (9%)

Query: 526  GPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTL 585
            G  A +  P +S +  + + +     S    G+ P      L     ++G +  ST+  +
Sbjct: 1280 GSIATTHFPESSTTSGRSEESTASHSSPDTNGITP------LPAHFTTSGRIAESTTFYI 1333

Query: 586  --GSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGL 643
              GS +T L       G  +   + Y    +     +  ++TSS+       L +  +  
Sbjct: 1334 SPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAEST 1393

Query: 644  HKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHT 703
            H      S   +G   LS    + H +   +         TL   S+T  +     +   
Sbjct: 1394 HTTAFPASTTTSG---LSQESTTFHSKPGST-------ETTLSPGSITTSS----FAQEF 1439

Query: 704  ATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPS 763
             T   Q G  L+  S  S  +  + E S     +P ST +     +H + M+  +  S  
Sbjct: 1440 TTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAF--SHSNTMSIHSQQSTP 1497

Query: 764  HGDSKSPGLLSSDNPQ-LSALLMGKANNNVGTGTCDKVNNIHPAVHTKTD-----NSVAS 817
              DS  PG   +  P  L+   +G+ +    + +        PA  T +D      +   
Sbjct: 1498 FPDS--PGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARSTASDLVGEPTTFYI 1555

Query: 818  SPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGME 860
            SPS   +T  P+  ST   T  S T   SP      ++ E +E
Sbjct: 1556 SPSPTYTTLFPASSSTSGLTEESTTFHTSPSFTSTIVSTESLE 1598


>gi|118766328 transmembrane and tetratricopeptide repeat containing
           4 isoform 2 [Homo sapiens]
          Length = 741

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 27/96 (28%), Positives = 49/96 (51%)

Query: 269 AIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLY 328
           A + L  +++  P+   +W  LG   +S+ + + A  SYR +I       D + ++G LY
Sbjct: 535 AEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLY 594

Query: 329 QQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYES 364
              N+ +DAL A+  A  L   H+ AW ++  L ++
Sbjct: 595 ADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDN 630



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 26/112 (23%), Positives = 54/112 (48%)

Query: 271 QYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQ 330
           Q  + +L   P + +  Y +G+  +  G    A   YR+++  +        ++G + ++
Sbjct: 469 QLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKE 528

Query: 331 QNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSK 382
           +N+  +A +    AVQ+    AAAWM+LG +  S  + + A + Y  A + +
Sbjct: 529 RNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHR 580



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 28/121 (23%), Positives = 56/121 (46%), Gaps = 1/121 (0%)

Query: 259 LGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASA 318
           L DK  + + AI+Y ++++  +P    +   LG       ++Q+A      ++      A
Sbjct: 492 LADKGNQTA-AIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFA 550

Query: 319 DTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNA 378
             W ++G++     +   A Q+Y  A++    +   + +LG LY   N+  DA+  + NA
Sbjct: 551 AAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNA 610

Query: 379 T 379
           T
Sbjct: 611 T 611


>gi|118766330 transmembrane and tetratricopeptide repeat containing
           4 isoform 1 [Homo sapiens]
          Length = 760

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 27/96 (28%), Positives = 49/96 (51%)

Query: 269 AIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLY 328
           A + L  +++  P+   +W  LG   +S+ + + A  SYR +I       D + ++G LY
Sbjct: 554 AEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLY 613

Query: 329 QQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYES 364
              N+ +DAL A+  A  L   H+ AW ++  L ++
Sbjct: 614 ADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDN 649



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 26/112 (23%), Positives = 54/112 (48%)

Query: 271 QYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQ 330
           Q  + +L   P + +  Y +G+  +  G    A   YR+++  +        ++G + ++
Sbjct: 488 QLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKE 547

Query: 331 QNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSK 382
           +N+  +A +    AVQ+    AAAWM+LG +  S  + + A + Y  A + +
Sbjct: 548 RNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHR 599



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 28/121 (23%), Positives = 56/121 (46%), Gaps = 1/121 (0%)

Query: 259 LGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASA 318
           L DK  + + AI+Y ++++  +P    +   LG       ++Q+A      ++      A
Sbjct: 511 LADKGNQTA-AIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFA 569

Query: 319 DTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNA 378
             W ++G++     +   A Q+Y  A++    +   + +LG LY   N+  DA+  + NA
Sbjct: 570 AAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNA 629

Query: 379 T 379
           T
Sbjct: 630 T 630


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 42.7 bits (99), Expect = 0.002
 Identities = 80/349 (22%), Positives = 134/349 (38%), Gaps = 35/349 (10%)

Query: 515  VAQVRSTGIPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPL--ANGPF 572
            + ++ +T      T  ++ P+++     P   LT       P   P         ++ P 
Sbjct: 4723 LTELTTTATTTASTGSTATPSSTPGTAPPPKVLT------SPATTPTATSSKATSSSSPR 4776

Query: 573  SAGHVPCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPW 632
            +A  +P  TS    ST T +      T  G+ G +P       T P    +    +  P 
Sbjct: 4777 TATTLPVLTSTATKSTATSVTPIPSST-LGTTGTLP----EQTTTPVATMSTIHPSSTP- 4830

Query: 633  KNQLSNSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQ--NGHPTLPSNSV 690
              + ++++  L    ++  A  +   P S+ G +  L    +        G    PS++ 
Sbjct: 4831 --ETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTP 4888

Query: 691  TQGAALNHLSSHTATSGGQQGITLTKESKPSGN-ILTVPETSRH----TGETP--NSTAS 743
                 L  L++ TAT+    G T T  S P    ILT P T+      TG T   +ST +
Sbjct: 4889 GTTWILTELTT-TATTTASTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTQA 4947

Query: 744  VEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNI 803
              G P+     T   V S     S SPG  ++    L AL   ++     T T       
Sbjct: 4948 TAGTPHVSTTATTPTVTSSKATPSSSPGTATA----LPAL---RSTATTPTATSFTAIPS 5000

Query: 804  HPAVHTKTDNSVASSPSSAISTATPS--PKSTEQTTTNSVTSLNSPHSG 850
                 T T  S  ++P++ +STATPS  P++   +T  + T+  +  +G
Sbjct: 5001 SSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATG 5049



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 70/317 (22%), Positives = 118/317 (37%), Gaps = 36/317 (11%)

Query: 562  CPGQPLANGPFSAGHVPCST----SRTLGSTDTILIGNNHITGSGSNGNVP---YLQRNA 614
            CP  P  +   +    P +T     +T  +T T   G+  I  S + G  P    L   A
Sbjct: 3554 CPSTPATSSTATPSSTPGTTWILTEQTTAATTTATTGSTAIPSS-TPGTAPPPKVLTSTA 3612

Query: 615  LTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQS-------SHSAGPNGERPLSSTGPSQ 667
             T     +  TSS+       L   T    K  +       S + G  G  P  +T P  
Sbjct: 3613 TTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMA 3672

Query: 668  HLQAAGSGIQNQNGHP-TLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNILT 726
             +         +  H  T+ +   T   A + +S+ ++T G    +T          + T
Sbjct: 3673 TMSTIHPSSTPETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILT---------ELTT 3723

Query: 727  VPETSRHTGET--PNSTASVEGL---PNHVHQMT----ADAVCSPSHGDSKSPGLLSSDN 777
               T+  TG T  P+ST     +   P+    +T    + A  S +   + +  +L+S  
Sbjct: 3724 AATTTAATGPTATPSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTS-T 3782

Query: 778  PQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTA-TPSPKSTEQT 836
                 ++  +A  +   GT   +  +     T T  SV + PSS++ TA T   ++T  T
Sbjct: 3783 ATTPTVISSRATPSSSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPT 3842

Query: 837  TTNSVTSLNSPHSGLHT 853
             T S  + +S    +HT
Sbjct: 3843 ATMSTATPSSTPETVHT 3859



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 71/305 (23%), Positives = 111/305 (36%), Gaps = 24/305 (7%)

Query: 562  CPGQPLANGPFSAGHVPCST----SRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTL 617
            CP  P  +   +    P +T      T  +T T   G+   T S + G    L   + T 
Sbjct: 4199 CPSTPATSSTATPSSTPGTTWILTKLTTTATTTESTGST-ATPSSTPGTTWILTEPSTTA 4257

Query: 618  PHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQ 677
                T  T S       Q +  T  +    ++ +   +   P SS G +  L A  S   
Sbjct: 4258 --TVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTAT 4315

Query: 678  NQNG--HPTLPSNSV-TQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHT 734
                     +PS+S+ T    L+  ++ TAT       +  + +  S  + T   T+R T
Sbjct: 4316 TPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRAT 4375

Query: 735  GE--TPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNV 792
            G   TP+ST             T     +PS     SPG   +    +S       + + 
Sbjct: 4376 GSVATPSSTPGTAHTTKVPTTTTTGFTVTPS----SSPGTARTPPVWISTTTTPTTSGST 4431

Query: 793  GTGTCDKVNNIHPAVHTKTDNSVAS----SPSSAISTA----TPSPKSTEQTTTNSVTSL 844
             T +        P V T T  +VA+    +PSS+  T+    TP   +T  TT     S 
Sbjct: 4432 VTPSSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSP 4491

Query: 845  NSPHS 849
            +SPH+
Sbjct: 4492 SSPHT 4496



 Score = 38.9 bits (89), Expect = 0.035
 Identities = 73/317 (23%), Positives = 108/317 (34%), Gaps = 37/317 (11%)

Query: 562  CPGQPLANGPFSAGHVPCST----SRTLGSTDTILIGNNHITGSGSNGNVP---YLQRNA 614
            CP  P  +        P +T      T  +T T   G+   T S + G  P    L   A
Sbjct: 4701 CPSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGST-ATPSSTPGTAPPPKVLTSPA 4759

Query: 615  LTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQS-------SHSAGPNGERPLSSTGPSQ 667
             T     +  TSS+       L   T    K  +       S + G  G  P  +T P  
Sbjct: 4760 TTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPEQTTTPVA 4819

Query: 668  HLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGIT--LTKESKPSGNIL 725
             +         +  H    S  +T  A     +S T+T     G T  LT+       + 
Sbjct: 4820 TMSTIHPSSTPETTHT---STVLTTKATTTRATSSTSTPSSTPGTTWILTE-------LT 4869

Query: 726  TVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDN-----PQL 780
            T   T+  TG T  + +S  G    + ++T  A  + S G + +P            P  
Sbjct: 4870 TAATTTAATGPTA-TPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPST 4928

Query: 781  SALLM---GKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTT 837
            +A +    G       T       ++     T T  S  ++PSS+  TAT  P      T
Sbjct: 4929 TATVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTAT 4988

Query: 838  TNSVTSLNS-PHSGLHT 853
            T + TS  + P S L T
Sbjct: 4989 TPTATSFTAIPSSSLGT 5005



 Score = 37.0 bits (84), Expect = 0.13
 Identities = 75/352 (21%), Positives = 121/352 (34%), Gaps = 50/352 (14%)

Query: 512  PTGVAQVRSTGIPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGP 571
            PTG     ST   +   A +  P  S +   P +  ++    S PG   A P        
Sbjct: 4935 PTG-----STATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPGTATALPALRSTATT 4989

Query: 572  FSAGHVPCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNA-----LTLPHNRTNLTS 626
             +A       S +LG+T T L      T + S                LT     T  T 
Sbjct: 4990 PTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATG 5049

Query: 627  SAEEPWKNQ-LSNSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTL 685
            S   P      +++T+      +  +A P+     + T P+    +  S I   +   T 
Sbjct: 5050 SVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPTTTPMSTMSTIHTSSTPETT 5109

Query: 686  PSNSV-TQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASV 744
             +++V T  A +   ++ TAT     G T          ILT   T+  T     STA++
Sbjct: 5110 HTSTVLTTTATMTRATNSTATPSSTLGTT---------RILTELTTTATTTAATGSTATL 5160

Query: 745  EGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIH 804
               P     +T                      P   A +M      V TG+    ++  
Sbjct: 5161 SSTPGTTWILT---------------------EPSTIATVM------VPTGSTATASSTL 5193

Query: 805  PAVHT-KTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTIN 855
               HT K   ++A+ P++  ST  PS  +   T T +V   + P   + T++
Sbjct: 5194 GTAHTPKVVTTMATMPTATASTV-PSSSTVGTTRTPAVLPSSLPTFSVSTVS 5244



 Score = 36.2 bits (82), Expect = 0.23
 Identities = 70/305 (22%), Positives = 108/305 (35%), Gaps = 24/305 (7%)

Query: 562  CPGQPLANGPFSAGHVPCST----SRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTL 617
            CP  P  +        P +T      T  +T T   G+   T S + G    L   + T 
Sbjct: 3052 CPSTPATSSTAMPSSTPGTTWILTELTTTATTTESTGST-ATPSSTPGTTWILTEPSTTA 3110

Query: 618  PHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQ 677
                T  T S       Q +  T  +    ++ +   +   P SS G +  L A  S   
Sbjct: 3111 --TVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPFSSPGTATALPALRSTAT 3168

Query: 678  NQNG--HPTLPSNSV-TQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHT 734
                     +PS+S+ T    L+  ++ TAT       +  +    S  + T   T+  T
Sbjct: 3169 TPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGAT 3228

Query: 735  GE--TPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNV 792
            G   TP+ST         +   T     +PS     SPG   +    +S         + 
Sbjct: 3229 GSVATPSSTPGTAHTTKVLTTTTTGFTATPS----SSPGTARTLPVWISTTTTPTTRGST 3284

Query: 793  GTGTCDKVNNIHPAVHTKTDNSVAS----SPSSAISTA----TPSPKSTEQTTTNSVTSL 844
             T +        P V T T  +VA+    +PSS+  T+    TP   +T  TT     S 
Sbjct: 3285 VTPSSIPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSLSP 3344

Query: 845  NSPHS 849
            +SPH+
Sbjct: 3345 SSPHT 3349



 Score = 32.7 bits (73), Expect = 2.5
 Identities = 60/252 (23%), Positives = 87/252 (34%), Gaps = 21/252 (8%)

Query: 615  LTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGP----NGERPLSSTGPSQHLQ 670
            LT P     +T           + +T G  K  +S +  P    +   P SS G +  L 
Sbjct: 3747 LTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALP 3806

Query: 671  AAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGIT--LTKESKPSGNILTVP 728
            A  S              S + G A   LS  T  +      T   T E+  +  +LT  
Sbjct: 3807 ALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTT 3866

Query: 729  ETS-RHTGE--TPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQLSALLM 785
             T+ R TG   TP+ST             T     +PS     SPG   +    +S    
Sbjct: 3867 TTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPS----SSPGTALTPPVWISTTTT 3922

Query: 786  GKANNNVGTGTCDKVNNIHPAVHTKTDNSVAS----SPSSAISTA----TPSPKSTEQTT 837
                 +  T +          V T T  +VA+    +PSS+  T+    TP   +T  TT
Sbjct: 3923 PTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATT 3982

Query: 838  TNSVTSLNSPHS 849
                   +SPH+
Sbjct: 3983 HGRSLPPSSPHT 3994



 Score = 32.3 bits (72), Expect = 3.3
 Identities = 42/160 (26%), Positives = 64/160 (40%), Gaps = 25/160 (15%)

Query: 700  SSHTATSGGQQGIT--LTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNH---VHQM 754
            +S TAT     G T  LTK +       T   T+  TG T   T+++   P         
Sbjct: 2584 TSSTATPSSTPGTTWILTKPT-------TTATTTASTGSTATPTSTLRTAPPPKVLTTTA 2636

Query: 755  TADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAV--HTKTD 812
            T   V S     S SPG         +A  +    +   T T   V  I  +    T T 
Sbjct: 2637 TTPTVTSSKATPSSSPG---------TATALPALRSTATTPTATSVTPIPSSSLGTTWTR 2687

Query: 813  NSVASSPSSAISTATPS--PKSTEQTTTNSVTSLNSPHSG 850
             S  ++P++ +STATPS  P++   +T  + T+  +  +G
Sbjct: 2688 LSQTTTPTATMSTATPSSTPETAHTSTVLTATATTTGATG 2727



 Score = 32.0 bits (71), Expect = 4.3
 Identities = 49/203 (24%), Positives = 70/203 (34%), Gaps = 15/203 (7%)

Query: 659  PLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGIT--LTK 716
            P SS G +  L A  S           P  S + G     LS  T  +      T   T 
Sbjct: 2648 PSSSPGTATALPALRSTATTPTATSVTPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTP 2707

Query: 717  ESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHG--DSKSPGLLS 774
            E+  +  +LT   T+  TG T  S A+    P   H        +       S SPG   
Sbjct: 2708 ETAHTSTVLTATATT--TGAT-GSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTAL 2764

Query: 775  SDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVAS----SPSSAISTA---- 826
            +    +S         +  T +          V T T  +VA+    +PSS+  T+    
Sbjct: 2765 TPPVWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTTH 2824

Query: 827  TPSPKSTEQTTTNSVTSLNSPHS 849
            TP   +T  TT       +SPH+
Sbjct: 2825 TPPVPNTMATTHGRSLPPSSPHT 2847



 Score = 32.0 bits (71), Expect = 4.3
 Identities = 76/352 (21%), Positives = 128/352 (36%), Gaps = 34/352 (9%)

Query: 525  NGPTADSSLPT-NSVSGQQPQLALTRVPS--VSQPGVRPACPGQPLANGPFSAGHVPCST 581
            + P   ++LP   S + +    + T +PS  +   G  P     P+A    S  H P ST
Sbjct: 3626 SSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMAT--MSTIH-PSST 3682

Query: 582  SRTLGSTDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQ 641
              T   T T+L      T + S+ + P        +    T   ++          +ST 
Sbjct: 3683 PETT-HTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTATPSSTP 3741

Query: 642  GLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSS 701
            G     +  S       P  ST  +   +A    ++      T P+  V    A    S 
Sbjct: 3742 GTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPT--VISSRATPSSSP 3799

Query: 702  HTATSGGQQGITLTKESKPSGNILTVPETSRHTG-------ETPN---STASVEGLPNHV 751
             TAT+     +  T  +  + ++  +P +S  T         TP    STA+    P  V
Sbjct: 3800 GTATA--LPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETV 3857

Query: 752  HQMTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTG-TCDKVNNIHPAVHTK 810
            H  T   V + +   +++ G +++ +         K      TG T    ++   A+   
Sbjct: 3858 HTST---VLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPP 3914

Query: 811  TDNSVASSPSSAISTATPS--PKSTEQ-------TTTNSVTSLNSPHSGLHT 853
               S  ++P++  ST TPS  P +T         TTT +  S+ +P S   T
Sbjct: 3915 VWISTTTTPTTRGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQT 3966



 Score = 31.2 bits (69), Expect = 7.3
 Identities = 41/159 (25%), Positives = 59/159 (37%), Gaps = 24/159 (15%)

Query: 697  NHLSSHTATSGGQQGITLTKESKPSGN-ILTVPETSRHTGETPNSTASVEGLPNHVHQMT 755
            +H  S  ATS      T T  S P    ILT P T+  T  +  STA+           T
Sbjct: 2576 SHCPSTPATSS-----TATPSSTPGTTWILTKPTTTATTTASTGSTATP----------T 2620

Query: 756  ADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSV 815
            +    +P       P  + +       +   KA  +   GT   +  +     T T  SV
Sbjct: 2621 STLRTAP-------PPKVLTTTATTPTVTSSKATPSSSPGTATALPALRSTATTPTATSV 2673

Query: 816  ASSPSSAISTA-TPSPKSTEQTTTNSVTSLNSPHSGLHT 853
               PSS++ T  T   ++T  T T S  + +S     HT
Sbjct: 2674 TPIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHT 2712



 Score = 31.2 bits (69), Expect = 7.3
 Identities = 73/341 (21%), Positives = 111/341 (32%), Gaps = 44/341 (12%)

Query: 523  IPNGPTADSS--------LPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSA 574
            +P G TA +S        L   + +   P +  +R    S PG   A P         +A
Sbjct: 3758 VPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPSSSPGTATALPALRSTATTPTA 3817

Query: 575  GHVPCSTSRTLGSTDTILIGNNHITGSGSNGNVPYLQRNA-----LTLPHNRTNLTSSAE 629
              V    S +LG+  T L      T + S                LT     T  T S  
Sbjct: 3818 TSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTTTTTRATGSVA 3877

Query: 630  EPWKNQLSNSTQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNS 689
             P      +ST G        +    G     S+ P   L        +    PT   ++
Sbjct: 3878 TP------SSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVW--ISTTTTPTTRGST 3929

Query: 690  VTQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEG--L 747
            VT  +     ++HTAT       T+   S  + +  T    + HT   PN+TA+  G  L
Sbjct: 3930 VTPSSIPG--TTHTATVLTTTTTTVATGSMATPSSSTQTSGTTHTPPVPNTTATTHGRSL 3987

Query: 748  PNHVHQMTADAVCSPSHG-----DSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNN 802
            P         A  S + G         P  ++S  P         A  +    +   +++
Sbjct: 3988 PPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTP--------AATTSTTQHSTPALSS 4039

Query: 803  IHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNSVTS 843
             HP+  T        SP S  +T     + T +TT  +  S
Sbjct: 4040 PHPSSRT------TESPPSPGTTTPGHTRGTSRTTATATPS 4074


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 65/351 (18%), Positives = 125/351 (35%), Gaps = 14/351 (3%)

Query: 528  TADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGS 587
            T  S + T S++G +   A T     +      +        G  +      S+  T+ S
Sbjct: 717  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 588  --------TDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNS 639
                      TI      ++ + S     + + +  T+     + T++        +  S
Sbjct: 777  IMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAS 836

Query: 640  TQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHL 699
            T G     ++ + G   E   +ST  S+   A+    +      T   +  T  +     
Sbjct: 837  TAGSETTTTTSTEG--SETTTASTEGSETTTASTESSETTTA--TTIGSETTTASTEGSE 892

Query: 700  SSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGE-TPNSTASVEGLPNHVHQMTADA 758
            ++ T+T G +     T+ S+ +    T  ET+  + E +  +TAS EG        T   
Sbjct: 893  TTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSE 952

Query: 759  VCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASS 818
              + S   S++  + +  +   +A   G     V T   +          T T +S  S 
Sbjct: 953  TITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSE 1012

Query: 819  PSSAISTATPSP-KSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKT 868
             ++  +T T +   STE + T +VT+  S  + ++T   E    S    +T
Sbjct: 1013 TTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSET 1063



 Score = 36.6 bits (83), Expect = 0.17
 Identities = 39/187 (20%), Positives = 71/187 (37%), Gaps = 13/187 (6%)

Query: 684 TLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTAS 743
           T  S   ++   ++   S T T     G+  T  S     + TV  T   T     +T S
Sbjct: 524 TTVSTEGSENTTVSTTGSETTTVS-TTGLETTTTSTEGSEMTTVSTTGAET-----TTDS 577

Query: 744 VEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNI 803
            EG              + S  DS++    ++D+   SA   G       T + +     
Sbjct: 578 TEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAS 637

Query: 804 HPAVHTKTDNS-------VASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTING 856
                T T ++       V+++ S    T+T   ++T  + T S T++++  SG  T++ 
Sbjct: 638 TEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSI 697

Query: 857 EGMEESQ 863
            G E ++
Sbjct: 698 TGSETTK 704



 Score = 32.3 bits (72), Expect = 3.3
 Identities = 43/216 (19%), Positives = 85/216 (39%), Gaps = 14/216 (6%)

Query: 655 NGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSV--TQGAALNHLSSH------TATS 706
           + E   +ST  S+   A+ +G +      T    +   T+G+    +S+        +T+
Sbjct: 600 DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 707 GGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGD 766
           G ++ IT T+ S+ +    T  ET+  T  +  +T S+ G        T     + S   
Sbjct: 660 GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 767 SKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTA 826
           S+      + +   +A   G       T   +  +    A  T ++ + AS+ SS  + A
Sbjct: 720 SEITTASITGSETTTASTEGSETTTASTEGSETTS----ASTTGSETTTASTTSSETTMA 775

Query: 827 TPSPKSTEQTTT--NSVTSLNSPHSGLHTINGEGME 860
           +     T   +T  +  T +++  S + T+  E  E
Sbjct: 776 SIMGSETTMASTIGSETTKVSTASSKMTTVFTENSE 811


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 65/351 (18%), Positives = 125/351 (35%), Gaps = 14/351 (3%)

Query: 528  TADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGS 587
            T  S + T S++G +   A T     +      +        G  +      S+  T+ S
Sbjct: 717  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 588  --------TDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNS 639
                      TI      ++ + S     + + +  T+     + T++        +  S
Sbjct: 777  IMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAS 836

Query: 640  TQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHL 699
            T G     ++ + G   E   +ST  S+   A+    +      T   +  T  +     
Sbjct: 837  TAGSETTTTTSTEG--SETTTASTEGSETTTASTESSETTTA--TTIGSETTTASTEGSE 892

Query: 700  SSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGE-TPNSTASVEGLPNHVHQMTADA 758
            ++ T+T G +     T+ S+ +    T  ET+  + E +  +TAS EG        T   
Sbjct: 893  TTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSE 952

Query: 759  VCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASS 818
              + S   S++  + +  +   +A   G     V T   +          T T +S  S 
Sbjct: 953  TITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSE 1012

Query: 819  PSSAISTATPSP-KSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKT 868
             ++  +T T +   STE + T +VT+  S  + ++T   E    S    +T
Sbjct: 1013 TTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSET 1063



 Score = 36.6 bits (83), Expect = 0.17
 Identities = 39/187 (20%), Positives = 71/187 (37%), Gaps = 13/187 (6%)

Query: 684 TLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTAS 743
           T  S   ++   ++   S T T     G+  T  S     + TV  T   T     +T S
Sbjct: 524 TTVSTEGSENTTVSTTGSETTTVS-TTGLETTTTSTEGSEMTTVSTTGAET-----TTDS 577

Query: 744 VEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNI 803
            EG              + S  DS++    ++D+   SA   G       T + +     
Sbjct: 578 TEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAS 637

Query: 804 HPAVHTKTDNS-------VASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTING 856
                T T ++       V+++ S    T+T   ++T  + T S T++++  SG  T++ 
Sbjct: 638 TEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSI 697

Query: 857 EGMEESQ 863
            G E ++
Sbjct: 698 TGSETTK 704



 Score = 32.3 bits (72), Expect = 3.3
 Identities = 43/216 (19%), Positives = 85/216 (39%), Gaps = 14/216 (6%)

Query: 655 NGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSV--TQGAALNHLSSH------TATS 706
           + E   +ST  S+   A+ +G +      T    +   T+G+    +S+        +T+
Sbjct: 600 DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 707 GGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGD 766
           G ++ IT T+ S+ +    T  ET+  T  +  +T S+ G        T     + S   
Sbjct: 660 GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 767 SKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTA 826
           S+      + +   +A   G       T   +  +    A  T ++ + AS+ SS  + A
Sbjct: 720 SEITTASITGSETTTASTEGSETTTASTEGSETTS----ASTTGSETTTASTTSSETTMA 775

Query: 827 TPSPKSTEQTTT--NSVTSLNSPHSGLHTINGEGME 860
           +     T   +T  +  T +++  S + T+  E  E
Sbjct: 776 SIMGSETTMASTIGSETTKVSTASSKMTTVFTENSE 811


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 65/351 (18%), Positives = 125/351 (35%), Gaps = 14/351 (3%)

Query: 528  TADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGS 587
            T  S + T S++G +   A T     +      +        G  +      S+  T+ S
Sbjct: 717  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 588  --------TDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNS 639
                      TI      ++ + S     + + +  T+     + T++        +  S
Sbjct: 777  IMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAS 836

Query: 640  TQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHL 699
            T G     ++ + G   E   +ST  S+   A+    +      T   +  T  +     
Sbjct: 837  TAGSETTTTTSTEG--SETTTASTEGSETTTASTESSETTTA--TTIGSETTTASTEGSE 892

Query: 700  SSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGE-TPNSTASVEGLPNHVHQMTADA 758
            ++ T+T G +     T+ S+ +    T  ET+  + E +  +TAS EG        T   
Sbjct: 893  TTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSE 952

Query: 759  VCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASS 818
              + S   S++  + +  +   +A   G     V T   +          T T +S  S 
Sbjct: 953  TITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSE 1012

Query: 819  PSSAISTATPSP-KSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKT 868
             ++  +T T +   STE + T +VT+  S  + ++T   E    S    +T
Sbjct: 1013 TTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSET 1063



 Score = 36.6 bits (83), Expect = 0.17
 Identities = 39/187 (20%), Positives = 71/187 (37%), Gaps = 13/187 (6%)

Query: 684 TLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTAS 743
           T  S   ++   ++   S T T     G+  T  S     + TV  T   T     +T S
Sbjct: 524 TTVSTEGSENTTVSTTGSETTTVS-TTGLETTTTSTEGSEMTTVSTTGAET-----TTDS 577

Query: 744 VEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNI 803
            EG              + S  DS++    ++D+   SA   G       T + +     
Sbjct: 578 TEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAS 637

Query: 804 HPAVHTKTDNS-------VASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTING 856
                T T ++       V+++ S    T+T   ++T  + T S T++++  SG  T++ 
Sbjct: 638 TEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSI 697

Query: 857 EGMEESQ 863
            G E ++
Sbjct: 698 TGSETTK 704



 Score = 32.3 bits (72), Expect = 3.3
 Identities = 43/216 (19%), Positives = 85/216 (39%), Gaps = 14/216 (6%)

Query: 655 NGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSV--TQGAALNHLSSH------TATS 706
           + E   +ST  S+   A+ +G +      T    +   T+G+    +S+        +T+
Sbjct: 600 DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 707 GGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGD 766
           G ++ IT T+ S+ +    T  ET+  T  +  +T S+ G        T     + S   
Sbjct: 660 GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 767 SKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTA 826
           S+      + +   +A   G       T   +  +    A  T ++ + AS+ SS  + A
Sbjct: 720 SEITTASITGSETTTASTEGSETTTASTEGSETTS----ASTTGSETTTASTTSSETTMA 775

Query: 827 TPSPKSTEQTTT--NSVTSLNSPHSGLHTINGEGME 860
           +     T   +T  +  T +++  S + T+  E  E
Sbjct: 776 SIMGSETTMASTIGSETTKVSTASSKMTTVFTENSE 811


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 65/351 (18%), Positives = 125/351 (35%), Gaps = 14/351 (3%)

Query: 528  TADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGS 587
            T  S + T S++G +   A T     +      +        G  +      S+  T+ S
Sbjct: 738  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 797

Query: 588  --------TDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNS 639
                      TI      ++ + S     + + +  T+     + T++        +  S
Sbjct: 798  IMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAS 857

Query: 640  TQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHL 699
            T G     ++ + G   E   +ST  S+   A+    +      T   +  T  +     
Sbjct: 858  TAGSETTTTTSTEG--SETTTASTEGSETTTASTESSETTTA--TTIGSETTTASTEGSE 913

Query: 700  SSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGE-TPNSTASVEGLPNHVHQMTADA 758
            ++ T+T G +     T+ S+ +    T  ET+  + E +  +TAS EG        T   
Sbjct: 914  TTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSE 973

Query: 759  VCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASS 818
              + S   S++  + +  +   +A   G     V T   +          T T +S  S 
Sbjct: 974  TITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSE 1033

Query: 819  PSSAISTATPSP-KSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKT 868
             ++  +T T +   STE + T +VT+  S  + ++T   E    S    +T
Sbjct: 1034 TTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSET 1084



 Score = 36.6 bits (83), Expect = 0.17
 Identities = 39/187 (20%), Positives = 71/187 (37%), Gaps = 13/187 (6%)

Query: 684 TLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTAS 743
           T  S   ++   ++   S T T     G+  T  S     + TV  T   T     +T S
Sbjct: 545 TTVSTEGSENTTVSTTGSETTTVS-TTGLETTTTSTEGSEMTTVSTTGAET-----TTDS 598

Query: 744 VEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNI 803
            EG              + S  DS++    ++D+   SA   G       T + +     
Sbjct: 599 TEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAS 658

Query: 804 HPAVHTKTDNS-------VASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTING 856
                T T ++       V+++ S    T+T   ++T  + T S T++++  SG  T++ 
Sbjct: 659 TEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSI 718

Query: 857 EGMEESQ 863
            G E ++
Sbjct: 719 TGSETTK 725



 Score = 32.3 bits (72), Expect = 3.3
 Identities = 43/216 (19%), Positives = 85/216 (39%), Gaps = 14/216 (6%)

Query: 655 NGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSV--TQGAALNHLSSH------TATS 706
           + E   +ST  S+   A+ +G +      T    +   T+G+    +S+        +T+
Sbjct: 621 DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 680

Query: 707 GGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGD 766
           G ++ IT T+ S+ +    T  ET+  T  +  +T S+ G        T     + S   
Sbjct: 681 GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 740

Query: 767 SKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTA 826
           S+      + +   +A   G       T   +  +    A  T ++ + AS+ SS  + A
Sbjct: 741 SEITTASITGSETTTASTEGSETTTASTEGSETTS----ASTTGSETTTASTTSSETTMA 796

Query: 827 TPSPKSTEQTTT--NSVTSLNSPHSGLHTINGEGME 860
           +     T   +T  +  T +++  S + T+  E  E
Sbjct: 797 SIMGSETTMASTIGSETTKVSTASSKMTTVFTENSE 832


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
            sapiens]
          Length = 1521

 Score = 42.4 bits (98), Expect = 0.003
 Identities = 65/351 (18%), Positives = 125/351 (35%), Gaps = 14/351 (3%)

Query: 528  TADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGS 587
            T  S + T S++G +   A T     +      +        G  +      S+  T+ S
Sbjct: 717  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 588  --------TDTILIGNNHITGSGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNS 639
                      TI      ++ + S     + + +  T+     + T++        +  S
Sbjct: 777  IMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAS 836

Query: 640  TQGLHKGQSSHSAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHL 699
            T G     ++ + G   E   +ST  S+   A+    +      T   +  T  +     
Sbjct: 837  TAGSETTTTTSTEG--SETTTASTEGSETTTASTESSETTTA--TTIGSETTTASTEGSE 892

Query: 700  SSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGE-TPNSTASVEGLPNHVHQMTADA 758
            ++ T+T G +     T+ S+ +    T  ET+  + E +  +TAS EG        T   
Sbjct: 893  TTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSE 952

Query: 759  VCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASS 818
              + S   S++  + +  +   +A   G     V T   +          T T +S  S 
Sbjct: 953  TITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSE 1012

Query: 819  PSSAISTATPSP-KSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQSPMKT 868
             ++  +T T +   STE + T +VT+  S  + ++T   E    S    +T
Sbjct: 1013 TTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSET 1063



 Score = 36.6 bits (83), Expect = 0.17
 Identities = 39/187 (20%), Positives = 71/187 (37%), Gaps = 13/187 (6%)

Query: 684 TLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNILTVPETSRHTGETPNSTAS 743
           T  S   ++   ++   S T T     G+  T  S     + TV  T   T     +T S
Sbjct: 524 TTVSTEGSENTTVSTTGSETTTVS-TTGLETTTTSTEGSEMTTVSTTGAET-----TTDS 577

Query: 744 VEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNI 803
            EG              + S  DS++    ++D+   SA   G       T + +     
Sbjct: 578 TEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTAS 637

Query: 804 HPAVHTKTDNS-------VASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTING 856
                T T ++       V+++ S    T+T   ++T  + T S T++++  SG  T++ 
Sbjct: 638 TEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSI 697

Query: 857 EGMEESQ 863
            G E ++
Sbjct: 698 TGSETTK 704



 Score = 31.2 bits (69), Expect = 7.3
 Identities = 43/216 (19%), Positives = 84/216 (38%), Gaps = 14/216 (6%)

Query: 655 NGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNSV--TQGAALNHLSSH------TATS 706
           + E   +ST  S+   A+ +G +      T    +   T+G+    +S+        +T+
Sbjct: 600 DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 707 GGQQGITLTKESKPSGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGD 766
           G ++ IT T+ S+ +    T  ET+  T  +  +T S+ G        T       S   
Sbjct: 660 GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEG 719

Query: 767 SKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTA 826
           S+      + +   +A   G       T   +  +    A  T ++ + AS+ SS  + A
Sbjct: 720 SEITTASITGSETTTASTEGSETTTASTEGSETTS----ASTTGSETTTASTTSSETTMA 775

Query: 827 TPSPKSTEQTTT--NSVTSLNSPHSGLHTINGEGME 860
           +     T   +T  +  T +++  S + T+  E  E
Sbjct: 776 SIMGSETTMASTIGSETTKVSTASSKMTTVFTENSE 811


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.129    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,901,758
Number of Sequences: 37866
Number of extensions: 2915396
Number of successful extensions: 14051
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 309
Number of HSP's that attempted gapping in prelim test: 12107
Number of HSP's gapped (non-prelim): 1855
length of query: 1401
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1286
effective length of database: 13,892,928
effective search space: 17866305408
effective search space used: 17866305408
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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