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Search of human proteins with 188528618
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|188528618 solute carrier family 6 (neurotransmitter
transporter, GABA), member 1 [Homo sapiens]
(599 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|188528618 solute carrier family 6 (neurotransmitter transport... 1234 0.0
gi|7657587 solute carrier family 6 (neurotransmitter transporter... 639 0.0
gi|21361581 solute carrier family 6 (neurotransmitter transporte... 638 0.0
gi|5032097 solute carrier family 6 member 8 isoform 1 [Homo sapi... 635 0.0
gi|171184408 solute carrier family 6 (neurotransmitter transport... 625 e-179
gi|171184406 solute carrier family 6 (neurotransmitter transport... 625 e-179
gi|171184404 solute carrier family 6 (neurotransmitter transport... 625 e-179
gi|197276623 solute carrier family 6 (neurotransmitter transport... 616 e-176
gi|54607094 solute carrier family 6 (neurotransmitter transporte... 616 e-176
gi|218563756 solute carrier family 6 member 8 isoform 2 [Homo sa... 616 e-176
gi|92859670 solute carrier family 6 (neurotransmitter transporte... 559 e-159
gi|4507041 solute carrier family 6 (neurotransmitter transporter... 542 e-154
gi|218563758 solute carrier family 6 member 8 isoform 3 [Homo sa... 533 e-151
gi|4557046 solute carrier family 6 member 2 [Homo sapiens] 529 e-150
gi|134304856 solute carrier family 6, member 7 [Homo sapiens] 527 e-149
gi|67782313 solute carrier family 6 member 9 isoform 1 [Homo sap... 519 e-147
gi|67782317 solute carrier family 6 member 9 isoform 3 [Homo sap... 518 e-147
gi|67782315 solute carrier family 6 member 9 isoform 2 [Homo sap... 518 e-147
gi|4507043 solute carrier family 6 member 4 [Homo sapiens] 509 e-144
gi|6005715 solute carrier family 6 (amino acid transporter), mem... 488 e-138
gi|194018524 solute carrier family 6, member 18 [Homo sapiens] 385 e-107
gi|51468073 solute carrier family 6, member 19 [Homo sapiens] 382 e-106
gi|11181770 solute carrier family 6, member 20 isoform 1 [Homo s... 365 e-101
gi|58219014 solute carrier family 6, member 17 [Homo sapiens] 330 2e-90
gi|12408638 solute carrier family 6, member 20 isoform 2 [Homo s... 308 1e-83
gi|33354281 solute carrier family 6, member 15 isoform 1 [Homo s... 266 5e-71
gi|55749589 solute carrier family 6, member 16 [Homo sapiens] 222 7e-58
gi|226437581 solute carrier family 6, member 15 isoform 3 [Homo ... 198 1e-50
gi|197276625 solute carrier family 6 (neurotransmitter transport... 188 1e-47
gi|21361693 solute carrier family 6, member 15 isoform 2 [Homo s... 175 9e-44
>gi|188528618 solute carrier family 6 (neurotransmitter transporter,
GABA), member 1 [Homo sapiens]
Length = 599
Score = 1234 bits (3192), Expect = 0.0
Identities = 599/599 (100%), Positives = 599/599 (100%)
Query: 1 MATNGSKVADGQISTEVSEAPVANDKPKTLVVKVQKKAADLPDRDTWKGRFDFLMSCVGY 60
MATNGSKVADGQISTEVSEAPVANDKPKTLVVKVQKKAADLPDRDTWKGRFDFLMSCVGY
Sbjct: 1 MATNGSKVADGQISTEVSEAPVANDKPKTLVVKVQKKAADLPDRDTWKGRFDFLMSCVGY 60
Query: 61 AIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAP 120
AIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAP
Sbjct: 61 AIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAP 120
Query: 121 MFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRCFSNYSMV 180
MFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRCFSNYSMV
Sbjct: 121 MFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRCFSNYSMV 180
Query: 181 NTTNMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVV 240
NTTNMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVV
Sbjct: 181 NTTNMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVV 240
Query: 241 YFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGL 300
YFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGL
Sbjct: 241 YFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGL 300
Query: 301 GSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASG 360
GSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASG
Sbjct: 301 GSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASG 360
Query: 361 PGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRR 420
PGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRR
Sbjct: 361 PGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRR 420
Query: 421 ELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRF 480
ELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRF
Sbjct: 421 ELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRF 480
Query: 481 YDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQMTPLTMGNYVFPKWGQGVGWLM 540
YDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQMTPLTMGNYVFPKWGQGVGWLM
Sbjct: 481 YDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQMTPLTMGNYVFPKWGQGVGWLM 540
Query: 541 ALSSMVLIPGYMAYMFLTLKGSLKQRIQVMVQPSEDIVRPENGPEQPQAGSSTSKEAYI 599
ALSSMVLIPGYMAYMFLTLKGSLKQRIQVMVQPSEDIVRPENGPEQPQAGSSTSKEAYI
Sbjct: 541 ALSSMVLIPGYMAYMFLTLKGSLKQRIQVMVQPSEDIVRPENGPEQPQAGSSTSKEAYI 599
>gi|7657587 solute carrier family 6 (neurotransmitter transporter,
GABA), member 11 [Homo sapiens]
Length = 632
Score = 639 bits (1649), Expect = 0.0
Identities = 302/553 (54%), Positives = 395/553 (71%), Gaps = 11/553 (1%)
Query: 36 KKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGV 95
K+ + +R W + +F++S G IGLGNVWRFPYLC KNGGGAFLIPY + I G+
Sbjct: 42 KRDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGI 101
Query: 96 PLFLLECSLGQYTSIGGLGVW-KLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNS 154
P+F LE +LGQ+TS GG+ W K+ P+F+G+G A V+ LN+YYI+I++WAI+YL N
Sbjct: 102 PVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNC 161
Query: 155 FTTTLPWKQCDNPWNTDRCF-------SNYSMVNTTNMTSAVVEFWERNMHQMTDGLDKP 207
FTT LPW C + WNT+ C SNYS V+ N TS V+EFWE + ++DG++
Sbjct: 162 FTTELPWATCGHEWNTENCVEFQKLNVSNYSHVSLQNATSPVMEFWEHRVLAISDGIEHI 221
Query: 208 GQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEG 267
G +RW LA+ L AW + YFCIWKG TGKVVY +AT+PYIML+IL RGVTLPGA EG
Sbjct: 222 GNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEG 281
Query: 268 ILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCIN 327
I FY+ P+ +LSD +VW+DA TQIFFSY + LG L ALGSYN+++NN YRD I++CC+N
Sbjct: 282 IKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLN 341
Query: 328 SCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFS 387
S TS AGF IFS++GFMA+ IA+VA SGPGLAF+AYP+AVT +P+SPLWA LFF
Sbjct: 342 SGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFFM 401
Query: 388 MLLMLGIDSQFCTVEGFITALVDEYPRLLRN--RRELFIAAVCIISYLIGLSNITQGGIY 445
ML+ LG+DSQF VE +TA+VD YP++ R RREL I A+ +ISY +GL +T+GG+Y
Sbjct: 402 MLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSVISYFLGLVMLTEGGMY 461
Query: 446 VFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTP 505
+F+LFD Y+ASGM LLF+ FEC+ I W YG NRFYDNI++M+G RP K CW TP
Sbjct: 462 IFQLFDSYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDMIGYRPPSLIKWCWMIMTP 521
Query: 506 IIVAGVFIFSAVQMTPLTMGN-YVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLK 564
I AG+FIF ++ PL N Y +P WG G+GWLMALSSM+ IP ++ +G+L
Sbjct: 522 GICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGWLMALSSMLCIPLWICITVWKTEGTLP 581
Query: 565 QRIQVMVQPSEDI 577
+++Q + PS D+
Sbjct: 582 EKLQKLTTPSTDL 594
>gi|21361581 solute carrier family 6 (neurotransmitter transporter,
GABA), member 13 [Homo sapiens]
Length = 602
Score = 638 bits (1646), Expect = 0.0
Identities = 302/577 (52%), Positives = 408/577 (70%), Gaps = 12/577 (2%)
Query: 23 ANDKPKTLVVKVQKKAAD-LPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGA 81
+N + K + ++KK D +R W + +F++S G IGLGNVWRFPYLC KNGGGA
Sbjct: 10 SNGETKPVYPVMEKKEEDGTLERGHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGA 69
Query: 82 FLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVW-KLAPMFKGVGLAAAVLSFWLNIYY 140
F IPY + L G+P+FLLE +LGQYTS GG+ W K+ P+F+G+G A+ ++ LN+YY
Sbjct: 70 FFIPYLVFLFTCGIPVFLLETALGQYTSQGGVTAWRKICPIFEGIGYASQMIVILLNVYY 129
Query: 141 IVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRCF----SNYSMVNTT-NMTSAVVEFWER 195
I++++WA++YL++SFT LPW C + WNT+ C +N S+ T+ N TS V+EFWER
Sbjct: 130 IIVLAWALFYLFSSFTIDLPWGGCYHEWNTEHCMEFQKTNGSLNGTSENATSPVIEFWER 189
Query: 196 NMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILF 255
+ +++DG+ G +RW LA+ L +AW++ YFCIWKGV TGKVVYF+AT+PY+ML++L
Sbjct: 190 RVLKISDGIQHLGALRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVVLL 249
Query: 256 FRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNN 315
RGVTLPGA +GI FY+ PN +L D +VW+DA TQIFFS+ + LG L ALGSYN +HNN
Sbjct: 250 IRGVTLPGAAQGIQFYLYPNLTRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNN 309
Query: 316 VYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQL 375
YRD I +C +NS TS AGF IFSI+GFM+ I++VA SGPGLAF+AYP AV L
Sbjct: 310 CYRDCIALCFLNSGTSFVAGFAIFSILGFMSQEQGVPISEVAESGPGLAFIAYPRAVVML 369
Query: 376 PISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLR--NRRELFIAAVCIISYL 433
P SPLWA FF M+++LG+DSQF VE +TALVD YP + R NRRE+ I V ++S+L
Sbjct: 370 PFSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPHVFRKKNRREVLILGVSVVSFL 429
Query: 434 IGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPC 493
+GL +T+GG+YVF+LFDYY+ASGM LLF+ FE + ++W YG RFYDNI++M+G RP
Sbjct: 430 VGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGAKRFYDNIEDMIGYRPW 489
Query: 494 IWWKLCWSFFTPIIVAGVFIFSAVQMTPLTMG-NYVFPKWGQGVGWLMALSSMVLIPGYM 552
K CW F TP + F+FS ++ TPLT Y +P WG +GWL+ALSSMV IP +
Sbjct: 490 PLIKYCWLFLTPAVCTATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALSSMVCIPAWS 549
Query: 553 AYMFLTLKGSLKQRIQVMVQPSEDIVRPENGPEQPQA 589
Y TLKG ++RI+ ++ P+ED+ P+ P P A
Sbjct: 550 LYRLGTLKGPFRERIRQLMCPAEDL--PQRNPAGPSA 584
>gi|5032097 solute carrier family 6 member 8 isoform 1 [Homo
sapiens]
Length = 635
Score = 635 bits (1639), Expect = 0.0
Identities = 298/570 (52%), Positives = 398/570 (69%), Gaps = 18/570 (3%)
Query: 20 APVANDKPKTLVVKVQKKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGG 79
AP D P L + A +P R+TW + DF+MSCVG+A+GLGNVWRFPYLC KNGG
Sbjct: 30 APAKGDGPVGLGTPGGRLA--VPPRETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGG 87
Query: 80 GAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIY 139
G FLIPY L + G+P+F LE SLGQ+ G + VW + P+FKG+G A+ V+ F+ N Y
Sbjct: 88 GVFLIPYVLIALVGGIPIFFLEISLGQFMKAGSINVWNICPLFKGLGYASMVIVFYCNTY 147
Query: 140 YIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRCF--------SNYSMVNTT-----NMT 186
YI++++W YYL SFTTTLPW C + WNT C +N S+ N T +
Sbjct: 148 YIMVLAWGFYYLVKSFTTTLPWATCGHTWNTPDCVEIFRHEDCANASLANLTCDQLADRR 207
Query: 187 SAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATY 246
S V+EFWE + +++ GL+ PG + W + + L W+LVYFC+WKGV TGK+VYF+AT+
Sbjct: 208 SPVIEFWENKVLRLSGGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATF 267
Query: 247 PYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIAL 306
PY++L++L RGV LPGA +GI++Y+ P++ KL +VW+DA TQIFFSY +GLG+L AL
Sbjct: 268 PYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTAL 327
Query: 307 GSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFL 366
GSYN F+NN Y+D+II+ INS TS FAGFV+FSI+GFMA I+ VA SGPGLAF+
Sbjct: 328 GSYNRFNNNCYKDAIILALINSGTSFFAGFVVFSILGFMAAEQGVHISKVAESGPGLAFI 387
Query: 367 AYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPR--LLRNRRELFI 424
AYP AVT +P++PLWA LFF MLL+LG+DSQF VEGFIT L+D P R +RE+ +
Sbjct: 388 AYPRAVTLMPVAPLWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISV 447
Query: 425 AAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNI 484
A C + ++I LS +T GG+YVF+LFDYYSASG +LL+ F+ECV ++W YG +RF D+I
Sbjct: 448 ALCCALCFVIDLSMVTDGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDI 507
Query: 485 QEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQMTPLTMGN-YVFPKWGQGVGWLMALS 543
M+G RPC W K CWSFFTP++ G+FIF+ V PL N YV+P WG+ +GW ALS
Sbjct: 508 ACMIGYRPCPWMKWCWSFFTPLVCMGIFIFNVVYYEPLVYNNTYVYPWWGEAMGWAFALS 567
Query: 544 SMVLIPGYMAYMFLTLKGSLKQRIQVMVQP 573
SM+ +P ++ L KG++ +R Q + QP
Sbjct: 568 SMLCVPLHLLGCLLRAKGTMAERWQHLTQP 597
>gi|171184408 solute carrier family 6 (neurotransmitter transporter,
betaine/GABA), member 12 [Homo sapiens]
Length = 614
Score = 625 bits (1613), Expect = e-179
Identities = 292/585 (49%), Positives = 406/585 (69%), Gaps = 10/585 (1%)
Query: 10 DGQISTEVSEAPVANDKPKTLVVKVQKKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWR 69
DG+++ + P + P+ Q+ + DR W + +F++S G IGLGNVWR
Sbjct: 2 DGKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWR 61
Query: 70 FPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVW-KLAPMFKGVGLA 128
FPYLC KNGGGAF IPYF+ G+P+F LE +LGQYTS G + W K+ P+F+G+GLA
Sbjct: 62 FPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLA 121
Query: 129 AAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRC--FSNYSMVNTT--- 183
+ V+ +LN+YYI+I++WA++YL++SFT+ LPW C+N WNT+ C F N+S T
Sbjct: 122 SVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTPF 181
Query: 184 -NMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYF 242
N TS V+EFWER + +T G+ G +RW LA+ L +AW++ YFCIWKGV TGKVVYF
Sbjct: 182 ENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYF 241
Query: 243 SATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGS 302
+AT+PY+ML+IL RGVTLPGA +GI++Y+ P+ +L D +VW+DA TQIFFS+ + G
Sbjct: 242 TATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGC 301
Query: 303 LIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPG 362
L ALGSYN +HNN Y+D I +C +NS TS AGFV+FSI+GFM+ I++VA SGPG
Sbjct: 302 LTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGPG 361
Query: 363 LAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLR--NRR 420
LAF+A+P+AVT +P+S LW+ LFF ML+ LG+DSQF VE +TA +D +PR LR RR
Sbjct: 362 LAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRR 421
Query: 421 ELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRF 480
EL I + ++ YLIGL +T+GG+Y+F+LFDYY++SG+ LLFL FE V ISW YG +RF
Sbjct: 422 ELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRF 481
Query: 481 YDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQMTPLTMGN-YVFPKWGQGVGWL 539
YDNI++M+G RP K+ W F TP + F+FS + TPL N YV+P WG +GW
Sbjct: 482 YDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWF 541
Query: 540 MALSSMVLIPGYMAYMFLTLKGSLKQRIQVMVQPSEDIVRPENGP 584
+ALSSMV +P ++ L +G ++R++ ++ P + +P+ P
Sbjct: 542 LALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHP 586
>gi|171184406 solute carrier family 6 (neurotransmitter transporter,
betaine/GABA), member 12 [Homo sapiens]
Length = 614
Score = 625 bits (1613), Expect = e-179
Identities = 292/585 (49%), Positives = 406/585 (69%), Gaps = 10/585 (1%)
Query: 10 DGQISTEVSEAPVANDKPKTLVVKVQKKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWR 69
DG+++ + P + P+ Q+ + DR W + +F++S G IGLGNVWR
Sbjct: 2 DGKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWR 61
Query: 70 FPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVW-KLAPMFKGVGLA 128
FPYLC KNGGGAF IPYF+ G+P+F LE +LGQYTS G + W K+ P+F+G+GLA
Sbjct: 62 FPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLA 121
Query: 129 AAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRC--FSNYSMVNTT--- 183
+ V+ +LN+YYI+I++WA++YL++SFT+ LPW C+N WNT+ C F N+S T
Sbjct: 122 SVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTPF 181
Query: 184 -NMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYF 242
N TS V+EFWER + +T G+ G +RW LA+ L +AW++ YFCIWKGV TGKVVYF
Sbjct: 182 ENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYF 241
Query: 243 SATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGS 302
+AT+PY+ML+IL RGVTLPGA +GI++Y+ P+ +L D +VW+DA TQIFFS+ + G
Sbjct: 242 TATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGC 301
Query: 303 LIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPG 362
L ALGSYN +HNN Y+D I +C +NS TS AGFV+FSI+GFM+ I++VA SGPG
Sbjct: 302 LTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGPG 361
Query: 363 LAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLR--NRR 420
LAF+A+P+AVT +P+S LW+ LFF ML+ LG+DSQF VE +TA +D +PR LR RR
Sbjct: 362 LAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRR 421
Query: 421 ELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRF 480
EL I + ++ YLIGL +T+GG+Y+F+LFDYY++SG+ LLFL FE V ISW YG +RF
Sbjct: 422 ELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRF 481
Query: 481 YDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQMTPLTMGN-YVFPKWGQGVGWL 539
YDNI++M+G RP K+ W F TP + F+FS + TPL N YV+P WG +GW
Sbjct: 482 YDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWF 541
Query: 540 MALSSMVLIPGYMAYMFLTLKGSLKQRIQVMVQPSEDIVRPENGP 584
+ALSSMV +P ++ L +G ++R++ ++ P + +P+ P
Sbjct: 542 LALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHP 586
>gi|171184404 solute carrier family 6 (neurotransmitter transporter,
betaine/GABA), member 12 [Homo sapiens]
Length = 614
Score = 625 bits (1613), Expect = e-179
Identities = 292/585 (49%), Positives = 406/585 (69%), Gaps = 10/585 (1%)
Query: 10 DGQISTEVSEAPVANDKPKTLVVKVQKKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWR 69
DG+++ + P + P+ Q+ + DR W + +F++S G IGLGNVWR
Sbjct: 2 DGKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWR 61
Query: 70 FPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVW-KLAPMFKGVGLA 128
FPYLC KNGGGAF IPYF+ G+P+F LE +LGQYTS G + W K+ P+F+G+GLA
Sbjct: 62 FPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLA 121
Query: 129 AAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRC--FSNYSMVNTT--- 183
+ V+ +LN+YYI+I++WA++YL++SFT+ LPW C+N WNT+ C F N+S T
Sbjct: 122 SVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTPF 181
Query: 184 -NMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYF 242
N TS V+EFWER + +T G+ G +RW LA+ L +AW++ YFCIWKGV TGKVVYF
Sbjct: 182 ENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYF 241
Query: 243 SATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGS 302
+AT+PY+ML+IL RGVTLPGA +GI++Y+ P+ +L D +VW+DA TQIFFS+ + G
Sbjct: 242 TATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGC 301
Query: 303 LIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPG 362
L ALGSYN +HNN Y+D I +C +NS TS AGFV+FSI+GFM+ I++VA SGPG
Sbjct: 302 LTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGPG 361
Query: 363 LAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLR--NRR 420
LAF+A+P+AVT +P+S LW+ LFF ML+ LG+DSQF VE +TA +D +PR LR RR
Sbjct: 362 LAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRR 421
Query: 421 ELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRF 480
EL I + ++ YLIGL +T+GG+Y+F+LFDYY++SG+ LLFL FE V ISW YG +RF
Sbjct: 422 ELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRF 481
Query: 481 YDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQMTPLTMGN-YVFPKWGQGVGWL 539
YDNI++M+G RP K+ W F TP + F+FS + TPL N YV+P WG +GW
Sbjct: 482 YDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWF 541
Query: 540 MALSSMVLIPGYMAYMFLTLKGSLKQRIQVMVQPSEDIVRPENGP 584
+ALSSMV +P ++ L +G ++R++ ++ P + +P+ P
Sbjct: 542 LALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHP 586
>gi|197276623 solute carrier family 6 (neurotransmitter transporter,
taurine), member 6 isoform a [Homo sapiens]
Length = 620
Score = 616 bits (1589), Expect = e-176
Identities = 286/546 (52%), Positives = 386/546 (70%), Gaps = 12/546 (2%)
Query: 42 PDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLE 101
P R+ W + DF++S G +GLGNVWRFPYLC KNGGGAFLIPYF+ L +G+P+F LE
Sbjct: 39 PQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLE 98
Query: 102 CSLGQYTSIGGLGVW-KLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLP 160
+GQYTS GG+ W K+ P+F G+G A+ V+ LN+YYIVI++WA YYL+ SF LP
Sbjct: 99 IIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELP 158
Query: 161 WKQCDNPWNTDRCFSN--------YSMVNTTNMTSAVVEFWERNMHQMTDGLDKPGQIRW 212
W C++ WNT C + + +++TN TS V+EFWERN+ ++ G+D PG ++W
Sbjct: 159 WAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKW 218
Query: 213 PLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYI 272
LA+ L + W++ +FCIWKGV TGKVVYF+AT+P+ ML++L RG+TLPGA GI FY+
Sbjct: 219 DLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYL 278
Query: 273 TPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSM 332
P+ +L D +VW+DA TQIFFSY + LG++ +LGSYN + N YRD +++ C+NS TS
Sbjct: 279 YPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSF 338
Query: 333 FAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLML 392
+GF IFSI+GFMA IADVA SGPGLAF+AYP+AVT +P+ W+ILFF MLL+L
Sbjct: 339 VSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLL 398
Query: 393 GIDSQFCTVEGFITALVDEYPRLLRN--RRELFIAAVCIISYLIGLSNITQGGIYVFKLF 450
G+DSQF VEG IT+LVD YP LR RRE+FIA VC ISYL+GL+ +T+GG+YVF+LF
Sbjct: 399 GLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLF 458
Query: 451 DYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAG 510
DYY+ASG+ LL++ FFEC I+W YG + YD I++M+G RP W K W+ TP++ G
Sbjct: 459 DYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVG 518
Query: 511 VFIFSAVQMTPLTMG-NYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRIQV 569
FIFS V+ PLT YV+P W G+GW +ALSSM+ +P + +G R++
Sbjct: 519 CFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRLCQTEGPFLVRVKY 578
Query: 570 MVQPSE 575
++ P E
Sbjct: 579 LLTPRE 584
>gi|54607094 solute carrier family 6 (neurotransmitter transporter,
taurine), member 6 isoform a [Homo sapiens]
Length = 620
Score = 616 bits (1589), Expect = e-176
Identities = 286/546 (52%), Positives = 386/546 (70%), Gaps = 12/546 (2%)
Query: 42 PDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLE 101
P R+ W + DF++S G +GLGNVWRFPYLC KNGGGAFLIPYF+ L +G+P+F LE
Sbjct: 39 PQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLE 98
Query: 102 CSLGQYTSIGGLGVW-KLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLP 160
+GQYTS GG+ W K+ P+F G+G A+ V+ LN+YYIVI++WA YYL+ SF LP
Sbjct: 99 IIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELP 158
Query: 161 WKQCDNPWNTDRCFSN--------YSMVNTTNMTSAVVEFWERNMHQMTDGLDKPGQIRW 212
W C++ WNT C + + +++TN TS V+EFWERN+ ++ G+D PG ++W
Sbjct: 159 WAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKW 218
Query: 213 PLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYI 272
LA+ L + W++ +FCIWKGV TGKVVYF+AT+P+ ML++L RG+TLPGA GI FY+
Sbjct: 219 DLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYL 278
Query: 273 TPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSM 332
P+ +L D +VW+DA TQIFFSY + LG++ +LGSYN + N YRD +++ C+NS TS
Sbjct: 279 YPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSF 338
Query: 333 FAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLML 392
+GF IFSI+GFMA IADVA SGPGLAF+AYP+AVT +P+ W+ILFF MLL+L
Sbjct: 339 VSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLL 398
Query: 393 GIDSQFCTVEGFITALVDEYPRLLRN--RRELFIAAVCIISYLIGLSNITQGGIYVFKLF 450
G+DSQF VEG IT+LVD YP LR RRE+FIA VC ISYL+GL+ +T+GG+YVF+LF
Sbjct: 399 GLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLF 458
Query: 451 DYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAG 510
DYY+ASG+ LL++ FFEC I+W YG + YD I++M+G RP W K W+ TP++ G
Sbjct: 459 DYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVG 518
Query: 511 VFIFSAVQMTPLTMG-NYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRIQV 569
FIFS V+ PLT YV+P W G+GW +ALSSM+ +P + +G R++
Sbjct: 519 CFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRLCQTEGPFLVRVKY 578
Query: 570 MVQPSE 575
++ P E
Sbjct: 579 LLTPRE 584
>gi|218563756 solute carrier family 6 member 8 isoform 2 [Homo
sapiens]
Length = 625
Score = 616 bits (1589), Expect = e-176
Identities = 292/570 (51%), Positives = 389/570 (68%), Gaps = 28/570 (4%)
Query: 20 APVANDKPKTLVVKVQKKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGG 79
AP D P L + A +P R+TW + DF+MSCVG+A+GLGNVWRFPYLC KNGG
Sbjct: 30 APAKGDGPVGLGTPGGRLA--VPPRETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGG 87
Query: 80 GAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIY 139
G FLIPY L + G+P+F LE SLGQ+ G + VW + P+FKG+G A+ V+ F+ N Y
Sbjct: 88 GVFLIPYVLIALVGGIPIFFLEISLGQFMKAGSINVWNICPLFKGLGYASMVIVFYCNTY 147
Query: 140 YIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRCF--------SNYSMVNTT-----NMT 186
YI++++W YYL SFTTTLPW C + WNT C +N S+ N T +
Sbjct: 148 YIMVLAWGFYYLVKSFTTTLPWATCGHTWNTPDCVEIFRHEDCANASLANLTCDQLADRR 207
Query: 187 SAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATY 246
S V+EFWE + +++ GL+ PG + W + + L W+LVYFC+WKGV TGK+VYF+AT+
Sbjct: 208 SPVIEFWENKVLRLSGGLEVPGALNWEVTLCLLACWVLVYFCVWKGVKSTGKIVYFTATF 267
Query: 247 PYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIAL 306
PY++L++L RGV LPGA +GI++Y+ P++ KL +VW+DA TQIFFSY +GLG+L AL
Sbjct: 268 PYVVLVVLLVRGVLLPGALDGIIYYLKPDWSKLGSPQVWIDAGTQIFFSYAIGLGALTAL 327
Query: 307 GSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFL 366
GSYN F+NN Y TS FAGFV+FSI+GFMA I+ VA SGPGLAF+
Sbjct: 328 GSYNRFNNNCYNG----------TSFFAGFVVFSILGFMAAEQGVHISKVAESGPGLAFI 377
Query: 367 AYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPR--LLRNRRELFI 424
AYP AVT +P++PLWA LFF MLL+LG+DSQF VEGFIT L+D P R +RE+ +
Sbjct: 378 AYPRAVTLMPVAPLWAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQREISV 437
Query: 425 AAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNI 484
A C + ++I LS +T GG+YVF+LFDYYSASG +LL+ F+ECV ++W YG +RF D+I
Sbjct: 438 ALCCALCFVIDLSMVTDGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDI 497
Query: 485 QEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQMTPLTMGN-YVFPKWGQGVGWLMALS 543
M+G RPC W K CWSFFTP++ G+FIF+ V PL N YV+P WG+ +GW ALS
Sbjct: 498 ACMIGYRPCPWMKWCWSFFTPLVCMGIFIFNVVYYEPLVYNNTYVYPWWGEAMGWAFALS 557
Query: 544 SMVLIPGYMAYMFLTLKGSLKQRIQVMVQP 573
SM+ +P ++ L KG++ +R Q + QP
Sbjct: 558 SMLCVPLHLLGCLLRAKGTMAERWQHLTQP 587
>gi|92859670 solute carrier family 6 (neurotransmitter transporter,
glycine), member 5 [Homo sapiens]
Length = 797
Score = 559 bits (1441), Expect = e-159
Identities = 273/612 (44%), Positives = 388/612 (63%), Gaps = 51/612 (8%)
Query: 1 MATNG-SKVADGQISTEVSEAPVANDKPKTLVVKVQKKAADLPDRDTWKGRFDFLMSCVG 59
+AT+G + V G ++T ++ D+ K R W + DF++S VG
Sbjct: 161 LATDGITSVLPGSVATVATQEDEQGDENKA--------------RGNWSSKLDFILSMVG 206
Query: 60 YAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWKLA 119
YA+GLGNVWRFPYL +NGGGAFLIPY + L AG+P+F LE SLGQ+ S G + VWK
Sbjct: 207 YAVGLGNVWRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAI 266
Query: 120 PMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRC------ 173
P +G G+A ++S + IYY VII + ++YL+ SF + LPW C+NPWNT C
Sbjct: 267 PALQGCGIAMLIISVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKL 326
Query: 174 ------------------------FSNYSMVNTTNMT-----SAVVEFWERNMHQMTDGL 204
+ N +MVN T+ S E+++ + +++ G+
Sbjct: 327 LLDSCVISDHPKIQIKNSTFCMTAYPNVTMVNFTSQANKTFVSGSEEYFKYFVLKISAGI 386
Query: 205 DKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGA 264
+ PG+IRWPLA+ L +AW++VY + KG+ +GKVVYF+AT+PY++L+IL RGVTLPGA
Sbjct: 387 EYPGEIRWPLALCLFLAWVIVYASLAKGIKTSGKVVYFTATFPYVVLVILLIRGVTLPGA 446
Query: 265 KEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVC 324
GI ++ITP + KL+D+ VW DAATQIFFS G LI L SYN FHNN YRD++IV
Sbjct: 447 GAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVT 506
Query: 325 CINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAIL 384
C NS TS+FAGFVIFS++GFMA+ K +I +VA GPG+AF+ YPEA+T+LP+SP WAI+
Sbjct: 507 CTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIAFVVYPEALTRLPLSPFWAII 566
Query: 385 FFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIISYLIGLSNITQGGI 444
FF MLL LG+D+ F T+E +T++ DE+P+ LR + +F CI +++G ITQGGI
Sbjct: 567 FFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGI 626
Query: 445 YVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFT 504
Y+F+L D Y+AS +L+ + FE V IS+ YG+ RF ++I+ M+G +P I+WK+CW+F T
Sbjct: 627 YMFQLVDTYAAS-YALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNIFWKVCWAFVT 685
Query: 505 PIIVAGVFIFSAVQMTPLTMGNYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLK 564
P I+ + FS Q P+T G+Y +P W +GWLM S++ IP G
Sbjct: 686 PTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMHLAPGRFI 745
Query: 565 QRIQVMVQPSED 576
+R++++ P D
Sbjct: 746 ERLKLVCSPQPD 757
>gi|4507041 solute carrier family 6 (neurotransmitter transporter,
dopamine), member 3 [Homo sapiens]
Length = 620
Score = 542 bits (1397), Expect = e-154
Identities = 256/553 (46%), Positives = 364/553 (65%), Gaps = 14/553 (2%)
Query: 35 QKKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAG 94
++ + DR+TW + DFL+S +G+A+ L NVWRFPYLC KNGGGAFL+PY L ++ AG
Sbjct: 51 RQSPVEAQDRETWGKKIDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAG 110
Query: 95 VPLFLLECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNS 154
+PLF +E +LGQ+ G GVWK+ P+ KGVG ++S ++ +Y VII+WA++YL++S
Sbjct: 111 MPLFYMELALGQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYLFSS 170
Query: 155 FTTTLPWKQCDNPWNTDRCFSNY--------SMVNTTNMTSAVVEFWER---NMHQMTDG 203
FTT LPW C+N WN+ C + S +N T T+ E++ER ++HQ + G
Sbjct: 171 FTTELPWIHCNNSWNSPNCSDAHPGDSSGDSSGLNDTFGTTPAAEYFERGVLHLHQ-SHG 229
Query: 204 LDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPG 263
+D G RW L L + +L+YF +WKGV +GKVV+ +AT PY++L L RGVTLPG
Sbjct: 230 IDDLGPPRWQLTACLVLVIVLLYFSLWKGVKTSGKVVWITATMPYVVLTALLLRGVTLPG 289
Query: 264 AKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIV 323
A +GI Y++ +F +L ++ VW+DAATQ+ FS G+G G LIA SYN F NN YRD+I+
Sbjct: 290 AIDGIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNCYRDAIVT 349
Query: 324 CCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAI 383
INS TS +GFV+FS +G+MA I DVA GPGL F+ YPEA+ LP+S WA+
Sbjct: 350 TSINSLTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFIIYPEAIATLPLSSAWAV 409
Query: 384 LFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIISYLIGLSNITQGG 443
+FF MLL LGIDS +E IT L+DE+ +LL RELF + + ++L+ L +T GG
Sbjct: 410 VFFIMLLTLGIDSAMGGMESVITGLIDEF-QLLHRHRELFTLFIVLATFLLSLFCVTNGG 468
Query: 444 IYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFF 503
IYVF L D++ A+G S+LF V E + ++WFYGV +F D+IQ+M G RP ++W+LCW
Sbjct: 469 IYVFTLLDHF-AAGTSILFGVLIEAIGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLV 527
Query: 504 TPIIVAGVFIFSAVQMTPLTMGNYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSL 563
+P + V + S V P G Y+FP W +GW++A SSM ++P Y AY F +L GS
Sbjct: 528 SPCFLLFVVVVSIVTFRPPHYGAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSF 587
Query: 564 KQRIQVMVQPSED 576
++++ + P +D
Sbjct: 588 REKLAYAIAPEKD 600
>gi|218563758 solute carrier family 6 member 8 isoform 3 [Homo
sapiens]
Length = 520
Score = 533 bits (1373), Expect = e-151
Identities = 248/479 (51%), Positives = 337/479 (70%), Gaps = 16/479 (3%)
Query: 111 GGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNT 170
G + VW + P+FKG+G A+ V+ F+ N YYI++++W YYL SFTTTLPW C + WNT
Sbjct: 4 GSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCGHTWNT 63
Query: 171 DRCF--------SNYSMVNTT-----NMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAIT 217
C +N S+ N T + S V+EFWE + +++ GL+ PG + W + +
Sbjct: 64 PDCVEIFRHEDCANASLANLTCDQLADRRSPVIEFWENKVLRLSGGLEVPGALNWEVTLC 123
Query: 218 LAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFR 277
L W+LVYFC+WKGV TGK+VYF+AT+PY++L++L RGV LPGA +GI++Y+ P++
Sbjct: 124 LLACWVLVYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGALDGIIYYLKPDWS 183
Query: 278 KLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFV 337
KL +VW+DA TQIFFSY +GLG+L ALGSYN F+NN Y+D+II+ INS TS FAGFV
Sbjct: 184 KLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINSGTSFFAGFV 243
Query: 338 IFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQ 397
+FSI+GFMA I+ VA SGPGLAF+AYP AVT +P++PLWA LFF MLL+LG+DSQ
Sbjct: 244 VFSILGFMAAEQGVHISKVAESGPGLAFIAYPRAVTLMPVAPLWAALFFFMLLLLGLDSQ 303
Query: 398 FCTVEGFITALVDEYPR--LLRNRRELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSA 455
F VEGFIT L+D P R +RE+ +A C + ++I LS +T GG+YVF+LFDYYSA
Sbjct: 304 FVGVEGFITGLLDLLPASYYFRFQREISVALCCALCFVIDLSMVTDGGMYVFQLFDYYSA 363
Query: 456 SGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFS 515
SG +LL+ F+ECV ++W YG +RF D+I M+G RPC W K CWSFFTP++ G+FIF+
Sbjct: 364 SGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSFFTPLVCMGIFIFN 423
Query: 516 AVQMTPLTMGN-YVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRIQVMVQP 573
V PL N YV+P WG+ +GW ALSSM+ +P ++ L KG++ +R Q + QP
Sbjct: 424 VVYYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLGCLLRAKGTMAERWQHLTQP 482
>gi|4557046 solute carrier family 6 member 2 [Homo sapiens]
Length = 617
Score = 529 bits (1362), Expect = e-150
Identities = 259/549 (47%), Positives = 357/549 (65%), Gaps = 15/549 (2%)
Query: 40 DLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFL 99
D R+TW + DFL+S VG+A+ L NVWRFPYLC KNGGGAFLIPY L LI AG+PLF
Sbjct: 52 DAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFY 111
Query: 100 LECSLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTL 159
+E +LGQY G VWK+ P FKGVG A +++ ++ YY VII+W++YYL++SFT L
Sbjct: 112 MELALGQYNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFTLNL 171
Query: 160 PWKQCDNPWNTDRC----------FSNYSMVNTTNMTSAVVEFWERNMHQM--TDGLDKP 207
PW C + WN+ C N++ + T A EF+ER + + + G+
Sbjct: 172 PWTDCGHTWNSPNCTDPKLLNGSVLGNHTKYSKYKFTPAA-EFYERGVLHLHESSGIHDI 230
Query: 208 GQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEG 267
G +W L + L + I++YF +WKGV +GKVV+ +AT PY +L +L GVTLPGA G
Sbjct: 231 GLPQWQLLLCLMVVVIVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNG 290
Query: 268 ILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCIN 327
I Y+ +F +L ++ VW+DAATQIFFS G G G LIA SYN F NN YRD+++ IN
Sbjct: 291 INAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSSIN 350
Query: 328 SCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFS 387
TS +GF IFSI+G+MAH K +I DVA G GL F+ YPEA++ L S WA++FF
Sbjct: 351 CITSFVSGFAIFSILGYMAHEHKVNIEDVATEGAGLVFILYPEAISTLSGSTFWAVVFFV 410
Query: 388 MLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIISYLIGLSNITQGGIYVF 447
MLL LG+DS +E IT L D++ ++L+ R+LF V ++L+ L IT+GGIYV
Sbjct: 411 MLLALGLDSSMGGMEAVITGLADDF-QVLKRHRKLFTFGVTFSTFLLALFCITKGGIYVL 469
Query: 448 KLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPII 507
L D + A+G S+LF V E + +SWFYGV+RF ++IQ+M+G RP ++W+LCW F +P
Sbjct: 470 TLLDTF-AAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFRPGLYWRLCWKFVSPAF 528
Query: 508 VAGVFIFSAVQMTPLTMGNYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRI 567
+ V + S + PLT +Y+FP W VGW +ALSSMVL+P Y+ Y FL+ +GSL +R+
Sbjct: 529 LLFVVVVSIINFKPLTYDDYIFPPWANWVGWGIALSSMVLVPIYVIYKFLSTQGSLWERL 588
Query: 568 QVMVQPSED 576
+ P +
Sbjct: 589 AYGITPENE 597
>gi|134304856 solute carrier family 6, member 7 [Homo sapiens]
Length = 636
Score = 527 bits (1357), Expect = e-149
Identities = 251/543 (46%), Positives = 360/543 (66%), Gaps = 11/543 (2%)
Query: 44 RDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECS 103
R W G+ DFL+SC+GY +GLGNVWRFPY NGGGAFL+PYFL L G+PLF LE S
Sbjct: 37 RGNWTGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLVPYFLMLAICGIPLFFLELS 96
Query: 104 LGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQ 163
LGQ++S+G L VWK++P+FKG G A ++ + IYY +II++ ++YL+ S T+ LPW+
Sbjct: 97 LGQFSSLGPLAVWKISPLFKGAGAAMLLIVGLVAIYYNMIIAYVLFYLFASLTSDLPWEH 156
Query: 164 CDNPWNTDRCFSNYSM--------VNTTNMTSAVVEFWERN-MH-QMTDGLDKPGQIRWP 213
C N WNT+ C + +N T S E+W R +H Q + G+ PG+IRW
Sbjct: 157 CGNWWNTELCLEHRVSKDGNGALPLNLTCTVSPSEEYWSRYVLHIQGSQGIGSPGEIRWN 216
Query: 214 LAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYIT 273
L + L +AW++V+ CI KGV +GKVVYF+AT+PY++L++L RGVTLPGA +GI FY+T
Sbjct: 217 LCLCLLLAWVIVFLCILKGVKSSGKVVYFTATFPYLILLMLLVRGVTLPGAWKGIQFYLT 276
Query: 274 PNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMF 333
P F L S+VW++AA QIF+S G+G G L+ SYN+FH N+YRD+ IV N+ TS+
Sbjct: 277 PQFHHLLSSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTFIVTLGNAITSIL 336
Query: 334 AGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLG 393
AGF IFS++G+M+ + VA +GPGLAF+ YP+A+T LP+SP W+ LFF MLL LG
Sbjct: 337 AGFAIFSVLGYMSQELGVPVDQVAKAGPGLAFVVYPQAMTMLPLSPFWSFLFFFMLLTLG 396
Query: 394 IDSQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIISYLIGLSNITQGGIYVFKLFDYY 453
+DSQF +E +TA+ DE+P LR ++ +F +C+ YL+GL T GG+Y L D Y
Sbjct: 397 LDSQFAFLETIVTAVTDEFPYYLRPKKAVFSGLICVAMYLMGLILTTDGGMYWLVLLDDY 456
Query: 454 SASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFI 513
SAS L+ +V C++++ YG+ RF +I M+G +P ++++ CW F +P + + +
Sbjct: 457 SAS-FGLMVVVITTCLAVTRVYGIQRFCRDIHMMLGFKPGLYFRACWLFLSPATLLALMV 515
Query: 514 FSAVQMTPLTMGNYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRIQVMVQP 573
+S V+ P G+Y FP W + +G LM L S ++IP M L +GSL +R+Q +P
Sbjct: 516 YSIVKYQPSEYGSYRFPPWAELLGILMGLLSCLMIPAGMLVAVLREEGSLWERLQQASRP 575
Query: 574 SED 576
+ D
Sbjct: 576 AMD 578
>gi|67782313 solute carrier family 6 member 9 isoform 1 [Homo
sapiens]
Length = 652
Score = 519 bits (1336), Expect = e-147
Identities = 257/601 (42%), Positives = 382/601 (63%), Gaps = 27/601 (4%)
Query: 1 MATNGSKVADGQISTEVSEAPVANDKPK---TLVVKVQKKAADLPDRDTWKGRFDFLMSC 57
M+ ++ A + + PVA P+ + + K+ +L R W + +F+++
Sbjct: 1 MSGGDTRAAIARPRMAAAHGPVAPSSPEQNGAVPSEATKRDQNLK-RGNWGNQIEFVLTS 59
Query: 58 VGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWK 117
VGYA+GLGNVWRFPYLC +NGGGAF+ PYF+ LIF G+PLF +E S GQ+ S G LGVW+
Sbjct: 60 VGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWR 119
Query: 118 LAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRCFSNY 177
++PMFKGVG V+S ++ IYY V+I A YY ++S T LPW C+NPWNT C
Sbjct: 120 ISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTHDCAGVL 179
Query: 178 SMVNTTN--------------------MTSAVVEFWERNMHQMTDGLDKPGQIRWPLAIT 217
N TN TS E+W + +++D + G++R PL
Sbjct: 180 DASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLSDDIGNFGEVRLPLLGC 239
Query: 218 LAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFR 277
L ++W++V+ C+ +GV +GKVVYF+AT+PY++L ILF RGVTL GA +GI++Y+TP +
Sbjct: 240 LGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFDGIMYYLTPQWD 299
Query: 278 KLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFV 337
K+ +++VW DAA+QIF+S G G LI + SYN FHNN YRDS+I+ N TS++AGFV
Sbjct: 300 KILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFV 359
Query: 338 IFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQ 397
IFSI+GFMA+ ++ VA GPGLAF+AYPEA+T LPISPLW++LFF ML++LG+ +Q
Sbjct: 360 IFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQ 419
Query: 398 FCTVEGFITALVDEYPRLLRNRRELFIA-AVCIISYLIGLSNITQGGIYVFKLFDYYSAS 456
FC +E +TA+VDE +++ ++ V + +L+G+ +Q GIY L D Y+AS
Sbjct: 420 FCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAAS 479
Query: 457 GMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSA 516
SL+ + CV+I + YG ++ +IQ M+G P +++++CW F +P I+ + +F+
Sbjct: 480 -FSLVVISCIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPAIIFFILVFTV 538
Query: 517 VQMTPLTMGNYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKG-SLKQRIQVMVQPSE 575
+Q P+T +Y +P W +G+LMALSS++ IP Y + G +L QR++ +PS
Sbjct: 539 IQYQPITYNHYQYPGWAVAIGFLMALSSVLCIPLYAMFRLCRTDGDTLLQRLKNATKPSR 598
Query: 576 D 576
D
Sbjct: 599 D 599
>gi|67782317 solute carrier family 6 member 9 isoform 3 [Homo
sapiens]
Length = 633
Score = 518 bits (1333), Expect = e-147
Identities = 249/555 (44%), Positives = 364/555 (65%), Gaps = 23/555 (4%)
Query: 44 RDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECS 103
R W + +F+++ VGYA+GLGNVWRFPYLC +NGGGAF+ PYF+ LIF G+PLF +E S
Sbjct: 27 RGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELS 86
Query: 104 LGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQ 163
GQ+ S G LGVW+++PMFKGVG V+S ++ IYY V+I A YY ++S T LPW
Sbjct: 87 FGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAY 146
Query: 164 CDNPWNTDRCFSNYSMVNTTN--------------------MTSAVVEFWERNMHQMTDG 203
C+NPWNT C N TN TS E+W + +++D
Sbjct: 147 CNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLSDD 206
Query: 204 LDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPG 263
+ G++R PL L ++W++V+ C+ +GV +GKVVYF+AT+PY++L ILF RGVTL G
Sbjct: 207 IGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEG 266
Query: 264 AKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIV 323
A +GI++Y+TP + K+ +++VW DAA+QIF+S G G LI + SYN FHNN YRDS+I+
Sbjct: 267 AFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVII 326
Query: 324 CCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAI 383
N TS++AGFVIFSI+GFMA+ ++ VA GPGLAF+AYPEA+T LPISPLW++
Sbjct: 327 SITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLWSL 386
Query: 384 LFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIA-AVCIISYLIGLSNITQG 442
LFF ML++LG+ +QFC +E +TA+VDE +++ ++ V + +L+G+ +Q
Sbjct: 387 LFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQA 446
Query: 443 GIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSF 502
GIY L D Y+AS SL+ + CV+I + YG ++ +IQ M+G P +++++CW F
Sbjct: 447 GIYWLLLMDNYAAS-FSLVVISCIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRF 505
Query: 503 FTPIIVAGVFIFSAVQMTPLTMGNYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKG- 561
+P I+ + +F+ +Q P+T +Y +P W +G+LMALSS++ IP Y + G
Sbjct: 506 VSPAIIFFILVFTVIQYQPITYNHYQYPGWAVAIGFLMALSSVLCIPLYAMFRLCRTDGD 565
Query: 562 SLKQRIQVMVQPSED 576
+L QR++ +PS D
Sbjct: 566 TLLQRLKNATKPSRD 580
>gi|67782315 solute carrier family 6 member 9 isoform 2 [Homo
sapiens]
Length = 706
Score = 518 bits (1333), Expect = e-147
Identities = 249/555 (44%), Positives = 364/555 (65%), Gaps = 23/555 (4%)
Query: 44 RDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECS 103
R W + +F+++ VGYA+GLGNVWRFPYLC +NGGGAF+ PYF+ LIF G+PLF +E S
Sbjct: 100 RGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFIMLIFCGIPLFFMELS 159
Query: 104 LGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQ 163
GQ+ S G LGVW+++PMFKGVG V+S ++ IYY V+I A YY ++S T LPW
Sbjct: 160 FGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFSSMTHVLPWAY 219
Query: 164 CDNPWNTDRCFSNYSMVNTTN--------------------MTSAVVEFWERNMHQMTDG 203
C+NPWNT C N TN TS E+W + +++D
Sbjct: 220 CNNPWNTHDCAGVLDASNLTNGSRPAALPSNLSHLLNHSLQRTSPSEEYWRLYVLKLSDD 279
Query: 204 LDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPG 263
+ G++R PL L ++W++V+ C+ +GV +GKVVYF+AT+PY++L ILF RGVTL G
Sbjct: 280 IGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPYVVLTILFVRGVTLEG 339
Query: 264 AKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIV 323
A +GI++Y+TP + K+ +++VW DAA+QIF+S G G LI + SYN FHNN YRDS+I+
Sbjct: 340 AFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFHNNCYRDSVII 399
Query: 324 CCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAI 383
N TS++AGFVIFSI+GFMA+ ++ VA GPGLAF+AYPEA+T LPISPLW++
Sbjct: 400 SITNCATSVYAGFVIFSILGFMANHLGVDVSRVADHGPGLAFVAYPEALTLLPISPLWSL 459
Query: 384 LFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIA-AVCIISYLIGLSNITQG 442
LFF ML++LG+ +QFC +E +TA+VDE +++ ++ V + +L+G+ +Q
Sbjct: 460 LFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTSQA 519
Query: 443 GIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSF 502
GIY L D Y+AS SL+ + CV+I + YG ++ +IQ M+G P +++++CW F
Sbjct: 520 GIYWLLLMDNYAAS-FSLVVISCIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRF 578
Query: 503 FTPIIVAGVFIFSAVQMTPLTMGNYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKG- 561
+P I+ + +F+ +Q P+T +Y +P W +G+LMALSS++ IP Y + G
Sbjct: 579 VSPAIIFFILVFTVIQYQPITYNHYQYPGWAVAIGFLMALSSVLCIPLYAMFRLCRTDGD 638
Query: 562 SLKQRIQVMVQPSED 576
+L QR++ +PS D
Sbjct: 639 TLLQRLKNATKPSRD 653
>gi|4507043 solute carrier family 6 member 4 [Homo sapiens]
Length = 630
Score = 509 bits (1310), Expect = e-144
Identities = 252/585 (43%), Positives = 375/585 (64%), Gaps = 17/585 (2%)
Query: 3 TNGSKVADGQISTEVSEAP---VANDKPKTLVVKVQKKAADLP--DRDTWKGRFDFLMSC 57
T G KV GQIS S P +D ++ A+L +R+TW + DFL+S
Sbjct: 33 TPGDKVESGQISNGYSAVPSPGAGDDTRHSIPATTTTLVAELHQGERETWGKKVDFLLSV 92
Query: 58 VGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVW- 116
+GYA+ LGNVWRFPY+C +NGGGAFL+PY + IF G+PLF +E +LGQY G + +W
Sbjct: 93 IGYAVDLGNVWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMELALGQYHRNGCISIWR 152
Query: 117 KLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRCFSN 176
K+ P+FKG+G A +++F++ YY I++WA+YYL +SFT LPW C N WNT C +
Sbjct: 153 KICPIFKGIGYAICIIAFYIASYYNTIMAWALYYLISSFTDQLPWTSCKNSWNTGNCTNY 212
Query: 177 YSMVNTT---NMTSAVVEFWERNMHQM--TDGLDKPGQIRWPLAITLAIAWILVYFCIWK 231
+S N T + TS EF+ R++ Q+ + GL G I W LA+ + + + ++YF IWK
Sbjct: 213 FSEDNITWTLHSTSPAEEFYTRHVLQIHRSKGLQDLGGISWQLALCIMLIFTVIYFSIWK 272
Query: 232 GVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQ 291
GV +GKVV+ +AT+PYI+L +L RG TLPGA G+LFY+ PN++KL ++ VW+DAA Q
Sbjct: 273 GVKTSGKVVWVTATFPYIILSVLLVRGATLPGAWRGVLFYLKPNWQKLLETGVWIDAAAQ 332
Query: 292 IFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKR 351
IFFS G G G L+A SYN F+NN Y+D+++ +N TS +GFVIF+++G+MA +
Sbjct: 333 IFFSLGPGFGVLLAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTVLGYMAEMRNE 392
Query: 352 SIADVAA-SGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVD 410
+++VA +GP L F+ Y EA+ +P S +AI+FF ML+ LG+DS F +EG ITA++D
Sbjct: 393 DVSEVAKDAGPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLEGVITAVLD 452
Query: 411 EYPRLLRNRRELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVS 470
E+P + RRE F+ AV I + L +T GG YV KL + Y A+G ++L + E V+
Sbjct: 453 EFPHVWAKRRERFVLAVVITCFFGSLVTLTFGGAYVVKLLEEY-ATGPAVLTVALIEAVA 511
Query: 471 ISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQMTP--LTMGNYV 528
+SWFYG+ +F +++EM+G P +W++CW +P+ + +FI + M+P L + Y
Sbjct: 512 VSWFYGITQFCRDVKEMLGFSPGWFWRICWVAISPLFL--LFIICSFLMSPPQLRLFQYN 569
Query: 529 FPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRIQVMVQP 573
+P W +G+ + SS + IP Y+AY + G+ K+RI + P
Sbjct: 570 YPYWSIILGYCIGTSSFICIPTYIAYRLIITPGTFKERIIKSITP 614
>gi|6005715 solute carrier family 6 (amino acid transporter), member
14 [Homo sapiens]
Length = 642
Score = 488 bits (1257), Expect = e-138
Identities = 241/573 (42%), Positives = 350/573 (61%), Gaps = 41/573 (7%)
Query: 43 DRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLEC 102
DR W + D+L+S +GYA+GLGNVWRFPYL NGGGAFLIPY + L AG+PLF LEC
Sbjct: 35 DRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLEC 94
Query: 103 SLGQYTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWK 162
SLGQ+ S+G + VW++ P+F+GVG+ ++S ++ IYY VII++++YY++ SF + LPWK
Sbjct: 95 SLGQFASLGPVSVWRILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSELPWK 154
Query: 163 QCDNPWNTDRCF----------------------SNYSMVNTTNMTS------------A 188
C + W+ C N S V+ N T
Sbjct: 155 NCSS-WSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIYQPGQLP 213
Query: 189 VVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPY 248
++W + Q + G+++ G I W LA+ L +AW++V ++KG+ +GKVVYF+A +PY
Sbjct: 214 SEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTALFPY 273
Query: 249 IMLIILFFRGVTLPGAKEGILFYI--TPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIAL 306
++L+IL RG TL GA +GI +YI NF KL ++EVW DAATQIF+S + G L+AL
Sbjct: 274 VVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGGLVAL 333
Query: 307 GSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHVTKRSIADVAASGPGLAFL 366
SYN F NN + D+I+VC N TS+FAGF IFSI+G MAH++ + ++ V SG LAF+
Sbjct: 334 SSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFDLAFI 393
Query: 367 AYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAA 426
AYPEA+ QLP P W+ILFF MLL LG+DSQF ++E T + D +P++++ R
Sbjct: 394 AYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKKMRVPITLG 453
Query: 427 VCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQE 486
C++ +L+GL +TQ GIY L D++ A G +L E V I W YG NRF ++ +
Sbjct: 454 CCLVLFLLGLVCVTQAGIYWVHLIDHFCA-GWGILIAAILELVGIIWIYGGNRFIEDTEM 512
Query: 487 MVGSRPCI---WWKLCWSFFTPIIVAGVFIFSAVQMTPLTMGNYVFPKWGQGVGWLMALS 543
M+G++ I WW+ CW TPI++ +FI+S VQ G +P WG +GW M +
Sbjct: 513 MIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYGAIPYPDWGVALGWCMIVF 572
Query: 544 SMVLIPGYMAYMFLTLKGSLKQRIQVMVQPSED 576
++ IP + KG++ QR+ +P+ +
Sbjct: 573 CIIWIPIMAIIKIIQAKGNIFQRLISCCRPASN 605
>gi|194018524 solute carrier family 6, member 18 [Homo sapiens]
Length = 628
Score = 385 bits (988), Expect = e-107
Identities = 204/527 (38%), Positives = 291/527 (55%), Gaps = 65/527 (12%)
Query: 38 AADLPD-RDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVP 96
A DL D R W + +L+SC G+A+GLGN+WRFPYLC GGGAFLIPY + L+F G+P
Sbjct: 11 ACDLGDERPKWDNKAQYLLSCTGFAVGLGNIWRFPYLCQTYGGGAFLIPYVIALVFEGIP 70
Query: 97 LFLLECSLGQYTSIGGLGVWK-LAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSF 155
+F +E ++GQ G +GVW ++P GVGL LSF +++YY I++W ++YL NSF
Sbjct: 71 IFHVELAIGQRLRKGSVGVWTAISPYLSGVGLGCVTLSFLISLYYNTIVAWVLWYLLNSF 130
Query: 156 TTTLPWKQCDNPWNTDRCFSNYSMVNTTNMTSAVVEFWERNMHQMTDGLDKPGQIRWPLA 215
LPW C N V +SAV FW R +T ++ G I+W L
Sbjct: 131 QHPLPWSSCPPDLNRT------GFVEECQGSSAVSYFWYRQTLNITADINDSGSIQWWLL 184
Query: 216 ITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPN 275
I LA +W +VY C+ +G+ TGKV+YF+A +PY++L I RG+TLPGA +G+++ TPN
Sbjct: 185 ICLAASWAVVYMCVIRGIETTGKVIYFTALFPYLVLTIFLIRGLTLPGATKGLIYLFTPN 244
Query: 276 FRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAG 335
L + VWLDAATQIFFS L G IA SYNS N+ +D++++ +N TS++A
Sbjct: 245 MHILQNPRVWLDAATQIFFSLSLAFGGHIAFASYNSPRNDCQKDAVVIALVNRMTSLYAS 304
Query: 336 FVIFSIVGFMA-----HVTKRSI------------------------------------- 353
+FS++GF A H R+I
Sbjct: 305 IAVFSVLGFKATNDYEHCLDRNILSLINDFDFPEQSISRDDYPAVLMHLNATWPKRVAQL 364
Query: 354 ----------ADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEG 403
D +ASGPGLAF+ + E +P +P+WA+LFF ML LG+ + F TVE
Sbjct: 365 PLKACLLEDFLDKSASGPGLAFVVFTETDLHMPGAPVWAMLFFGMLFTLGLSTMFGTVEA 424
Query: 404 FITALVD--EYPRLLRNRRELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLL 461
IT L+D PR + +E VC++ +L Q G Y ++FD ++AS +LL
Sbjct: 425 VITPLLDVGVLPRWV--PKEALTGLVCLVCFLSATCFTLQSGNYWLEIFDNFAAS-PNLL 481
Query: 462 FLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIV 508
L F E V + + YG+ RF D+I M G RP +W+L W +P+++
Sbjct: 482 MLAFLEVVGVVYVYGMKRFCDDIAWMTGRRPSPYWRLTWRVVSPLLL 528
>gi|51468073 solute carrier family 6, member 19 [Homo sapiens]
Length = 634
Score = 382 bits (981), Expect = e-106
Identities = 203/582 (34%), Positives = 310/582 (53%), Gaps = 75/582 (12%)
Query: 44 RDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECS 103
R W + ++++C+G+ +GLGNVWRFPYLC +GGGAF+IP+ + L+ G+PL LE +
Sbjct: 32 RPKWDNKAQYMLTCLGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLLYLEFA 91
Query: 104 LGQYTSIGGLGVWK-LAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWK 162
+GQ G LGVW + P KG+GLA+ + SF + +YY IISW ++YL+NSF LPW
Sbjct: 92 IGQRLRRGSLGVWSSIHPALKGLGLASMLTSFMVGLYYNTIISWIMWYLFNSFQEPLPWS 151
Query: 163 QCDNPWNTDRCFSNYSMVNTTNMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAW 222
C P N ++ V+ +S V FW R ++ + G I+W + + LA AW
Sbjct: 152 DC--PLNENQT----GYVDECARSSPVDYFWYRETLNISTSISDSGSIQWWMLLCLACAW 205
Query: 223 ILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDS 282
++Y C +G+ TGK VY ++T PY++L I RG+TL GA GI+F TPN +L+
Sbjct: 206 SVLYMCTIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNVTELAQP 265
Query: 283 EVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIV 342
+ WLDA Q+FFS+ L G LI+ SYNS HNN +DS+IV IN TS++ V++S++
Sbjct: 266 DTWLDAGAQVFFSFSLAFGGLISFSSYNSVHNNCEKDSVIVSIINGFTSVYVAIVVYSVI 325
Query: 343 GFMA------------------------HVTKRSIADV---------------------- 356
GF A +VT+ + D+
Sbjct: 326 GFRATQRYDDCFSTNILTLINGFDLPEGNVTQENFVDMQQRCNASDPAAYAQLVFQTCDI 385
Query: 357 ------AASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVD 410
A G GLAF+ + EA+T++P+SPLW++LFF ML LG+ S F +EG + L D
Sbjct: 386 NAFLSEAVEGTGLAFIVFTEAITKMPLSPLWSVLFFIMLFCLGLSSMFGNMEGVVVPLQD 445
Query: 411 EYPRLLRNRRELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVS 470
+ +E+ +C+ ++LIG G Y L D Y+ S + LL + F E S
Sbjct: 446 LRVIPPKWPKEVLTGLICLGTFLIGFIFTLNSGQYWLSLLDSYAGS-IPLLIIAFCEMFS 504
Query: 471 ISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQMTPLTMGNYV-- 528
+ + YGV+RF +I+ M+G +P I+W++ W +P+++ +F+F V + +
Sbjct: 505 VVYVYGVDRFNKDIEFMIGHKPNIFWQVTWRVVSPLLMLIIFLFFFVVEVSQELTYSIWD 564
Query: 529 -------------FPKWGQGVGWLMALSSMVLIPGYMAYMFL 557
+P W V ++A + IPGY Y +
Sbjct: 565 PGYEEFPKSQKISYPNWVYVVVVIVAGVPSLTIPGYAIYKLI 606
>gi|11181770 solute carrier family 6, member 20 isoform 1 [Homo
sapiens]
Length = 592
Score = 365 bits (936), Expect = e-101
Identities = 199/552 (36%), Positives = 296/552 (53%), Gaps = 64/552 (11%)
Query: 44 RDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECS 103
R W F+ +C+ YA+GLGNVWRFPYLC GGG+FL+PY + LI G+PL LE +
Sbjct: 5 RPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELA 64
Query: 104 LGQYTSIGGLGVWK-LAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWK 162
+GQ G +G W+ ++P GVG+A+ V+SF+L++YY VI +WA +YL++SF LPW
Sbjct: 65 VGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWS 124
Query: 163 QCDNPWNTDRCFSNYSMVNTTNMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAW 222
C P N + + Y S+ FW R ++ L + G ++W A+ L +AW
Sbjct: 125 VC--PLNGNH--TGYD--EECEKASSTQYFWYRKTLNISPSLQENGGVQWEPALCLLLAW 178
Query: 223 ILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDS 282
++VY CI +G TGKVVYF+A+ PY +LII RG+TL GA G+++ TP +L++
Sbjct: 179 LVVYLCILRGTESTGKVVYFTASLPYCVLIIYLIRGLTLHGATNGLMYMFTPKIEQLANP 238
Query: 283 EVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIV 342
+ W++AATQIFFS GLG GSLIA SYN NN + +IIV INS TS+FA V FSI
Sbjct: 239 KAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINSFTSIFASIVTFSIY 298
Query: 343 ---------------------------------------GFMA---------------HV 348
G++A +
Sbjct: 299 GFKATFNYENCLKKVSLLLTNTFDLEDGFLTASNLEQVKGYLASAYPSKYSEMFPQIKNC 358
Query: 349 TKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITAL 408
+ S D A G GLAF+ Y EA+ + +S LW++L+F MLLMLGI S +T L
Sbjct: 359 SLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSMLGNTAAILTPL 418
Query: 409 VDEYPRLLRNRRELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFEC 468
D +E VC+++ IG+ + G Y F +F+ Y+A+ +SLL +V E
Sbjct: 419 TDSKIISSHLPKEAISGLVCLVNCAIGMVFTMEAGNYWFDIFNDYAAT-LSLLLIVLVET 477
Query: 469 VSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQMTPLTMGNYV 528
+++ + YG+ RF +++ M G +WK+ W+ +P+++ +F+F + G
Sbjct: 478 IAVCYVYGLRRFESDLKAMTGRAVSWYWKVMWAGVSPLLIVSLFVFYLSDY--ILTGTLK 535
Query: 529 FPKWGQGVGWLM 540
+ W G L+
Sbjct: 536 YQAWDASQGQLV 547
>gi|58219014 solute carrier family 6, member 17 [Homo sapiens]
Length = 727
Score = 330 bits (847), Expect = 2e-90
Identities = 180/595 (30%), Positives = 302/595 (50%), Gaps = 90/595 (15%)
Query: 33 KVQKKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIF 92
K ++ D DR W + ++++ +G+++GLGN+WRFPYLC KNGGGA+L+PY + LI
Sbjct: 49 KAVEEELDAEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLII 108
Query: 93 AGVPLFLLECSLGQYTSIGGLGVWK-LAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYL 151
G+PLF LE ++GQ G +GVW + P G+G ++ ++ ++ +YY VII W+I+Y
Sbjct: 109 IGIPLFFLELAVGQRIRRGSIGVWHYICPRLGGIGFSSCIVCLFVGLYYNVIIGWSIFYF 168
Query: 152 YNSFTTTLPWKQCDNPWNTDRCFSNYSMVNTT-NMTSAVVEFWERNMHQMTDGLDKPGQI 210
+ SF LPW +C N + ++V +SA FW R ++D + + G +
Sbjct: 169 FKSFQYPLPWSECPVVRN-----GSVAVVEAECEKSSATTYFWYREALDISDSISESGGL 223
Query: 211 RWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILF 270
W + + L +AW +V + KG+ +GKV+YFS+ +PY++L RG+ L GA +GIL
Sbjct: 224 NWKMTLCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLRGAVDGILH 283
Query: 271 YITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLI----------------ALGSYNSFHN 314
TP K+ D +VW +AATQ+FF+ GLG G +I AL S+ +F
Sbjct: 284 MFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAALVSFINFFT 343
Query: 315 NVYRDSIIVC------------CINSCTSMFAGFVIFSIVGF--------MAHVTKRSIA 354
+V ++ C+ G++ +++ +H+T +
Sbjct: 344 SVLATLVVFAVLGFKANIMNEKCVVENAEKILGYLNTNVLSRDLIPPHVNFSHLTTKDYM 403
Query: 355 ----------------------------DVAASGPGLAFLAYPEAVTQLPISPLWAILFF 386
D + G GLAF+A+ EA+T P SP W+++FF
Sbjct: 404 EMYNVIMTVKEDQFSALGLDPCLLEDELDKSVQGTGLAFIAFTEAMTHFPASPFWSVMFF 463
Query: 387 SMLLMLGIDSQFCTVEGFITALVDEYPRLLRNRRELFIAAVCIISYLIGLSNITQGGIYV 446
ML+ LG+ S T+ G T ++D + + +E+F C+ ++L+GL + + G Y
Sbjct: 464 LMLINLGLGSMIGTMAGITTPIIDTF----KVPKEMFTVGCCVFAFLVGLLFVQRSGNYF 519
Query: 447 FKLFDYYSASGMSLLFLVFFECVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPI 506
+FD YSA+ + L +V E ++++W YG +F + EM+G RP ++ W F +P+
Sbjct: 520 VTMFDDYSAT-LPLTLIVILENIAVAWIYGTKKFMQELTEMLGFRPYRFYFYMWKFVSPL 578
Query: 507 IVAGVFIFSAVQM--TPLTMGNYV----------FPKWGQGVGWLMALSSMVLIP 549
+A + S +Q+ TP ++ FP W + L+ L + +P
Sbjct: 579 CMAVLTTASIIQLGVTPPGYSAWIKEEAAERYLYFPNWAMAL--LITLIVVATLP 631
>gi|12408638 solute carrier family 6, member 20 isoform 2 [Homo
sapiens]
Length = 555
Score = 308 bits (788), Expect = 1e-83
Identities = 180/552 (32%), Positives = 271/552 (49%), Gaps = 101/552 (18%)
Query: 44 RDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECS 103
R W F+ +C+ YA+GLGNVWRFPYLC GGG+FL+PY + LI G+PL LE +
Sbjct: 5 RPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELA 64
Query: 104 LGQYTSIGGLGVWK-LAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWK 162
+GQ G +G W+ ++P GVG+A+ V+SF+L++YY VI +WA +YL++SF LPW
Sbjct: 65 VGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWS 124
Query: 163 QCDNPWNTDRCFSNYSMVNTTNMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAW 222
C P N + + Y S+ FW R ++ L + G ++W A+ L +AW
Sbjct: 125 VC--PLNGNH--TGYD--EECEKASSTQYFWYRKTLNISPSLQENGGVQWEPALCLLLAW 178
Query: 223 ILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDS 282
++VY CI +G TGK+ +L++
Sbjct: 179 LVVYLCILRGTESTGKI-------------------------------------EQLANP 201
Query: 283 EVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIV 342
+ W++AATQIFFS GLG GSLIA SYN NN + +IIV INS TS+FA V FSI
Sbjct: 202 KAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINSFTSIFASIVTFSIY 261
Query: 343 ---------------------------------------GFMA---------------HV 348
G++A +
Sbjct: 262 GFKATFNYENCLKKVSLLLTNTFDLEDGFLTASNLEQVKGYLASAYPSKYSEMFPQIKNC 321
Query: 349 TKRSIADVAASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITAL 408
+ S D A G GLAF+ Y EA+ + +S LW++L+F MLLMLGI S +T L
Sbjct: 322 SLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSMLGNTAAILTPL 381
Query: 409 VDEYPRLLRNRRELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFEC 468
D +E VC+++ IG+ + G Y F +F+ Y+A+ +SLL +V E
Sbjct: 382 TDSKIISSHLPKEAISGLVCLVNCAIGMVFTMEAGNYWFDIFNDYAAT-LSLLLIVLVET 440
Query: 469 VSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQMTPLTMGNYV 528
+++ + YG+ RF +++ M G +WK+ W+ +P+++ +F+F + G
Sbjct: 441 IAVCYVYGLRRFESDLKAMTGRAVSWYWKVMWAGVSPLLIVSLFVFYLSDY--ILTGTLK 498
Query: 529 FPKWGQGVGWLM 540
+ W G L+
Sbjct: 499 YQAWDASQGQLV 510
>gi|33354281 solute carrier family 6, member 15 isoform 1 [Homo
sapiens]
Length = 730
Score = 266 bits (679), Expect = 5e-71
Identities = 127/334 (38%), Positives = 198/334 (59%), Gaps = 7/334 (2%)
Query: 16 EVSEAPVANDKPKTLVVKVQKKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCG 75
+ SE V + K V+ + D +R W + ++++ VG+++GLGNVWRFPYLC
Sbjct: 35 KTSELIVDGQEEKDTDVEEGSEVED--ERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQ 92
Query: 76 KNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWK-LAPMFKGVGLAAAVLSF 134
KNGGGA+L+PY + L+ G+PLF LE S+GQ G +GVW ++P G+G A+ V+ +
Sbjct: 93 KNGGGAYLLPYLILLMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCY 152
Query: 135 WLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRCFSNYSMVNTTNMTSAVVEFWE 194
++ +YY VII W+++Y SF LPW QC N F + +SA +W
Sbjct: 153 FVALYYNVIIGWSLFYFSQSFQQPLPWDQCPLVKNASHTF----VEPECEQSSATTYYWY 208
Query: 195 RNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIIL 254
R ++ + + G + W + I L AW++V + KG+ +GK++YFS+ +PY++LI
Sbjct: 209 REALNISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKIIYFSSLFPYVVLICF 268
Query: 255 FFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHN 314
R L G+ +GI TP + + +VW +AATQ+FF+ GLG G +IA SYN N
Sbjct: 269 LIRAFLLNGSIDGIRHMFTPKLEIMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDN 328
Query: 315 NVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAHV 348
N + D+++V IN TS+ A V+F+++GF A+V
Sbjct: 329 NCHFDAVLVSFINFFTSVLATLVVFAVLGFKANV 362
Score = 125 bits (314), Expect = 1e-28
Identities = 57/163 (34%), Positives = 103/163 (63%), Gaps = 5/163 (3%)
Query: 357 AASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLL 416
A G GLAF+A+ EA+T P SP W+++FF ML+ LG+ S F T+EG +T +VD +
Sbjct: 435 AVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIEGIVTPIVDTF---- 490
Query: 417 RNRRELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYG 476
+ R+E+ C++++ IGL + + G Y +FD YSA+ + LL +V E +++ + YG
Sbjct: 491 KVRKEILTVICCLLAFCIGLIFVQRSGNYFVTMFDDYSAT-LPLLIVVILENIAVCFVYG 549
Query: 477 VNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQM 519
+++F +++++M+G P ++ W + +P+++ + I S V M
Sbjct: 550 IDKFMEDLKDMLGFAPSRYYYYMWKYISPLMLLSLLIASVVNM 592
>gi|55749589 solute carrier family 6, member 16 [Homo sapiens]
Length = 736
Score = 222 bits (566), Expect = 7e-58
Identities = 167/640 (26%), Positives = 278/640 (43%), Gaps = 100/640 (15%)
Query: 4 NGSKVADGQIST---------EVSEAPVANDKPKTLVVKV--QKKAADLPDRDTWKGRFD 52
+ ++VA+ Q T E A N KP V++ +K++ L R W + +
Sbjct: 52 SAARVAEAQARTSQPKQISVLEALTASALNQKPTHEKVQMTEKKESEVLLARPFWSSKTE 111
Query: 53 FLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGG 112
++++ VG+++ +WRF YL +GG +F Y L GVPL LE + GQ GG
Sbjct: 112 YILAQVGFSMKPSCLWRFAYLWLNSGGCSFAAIYIFMLFLVGVPLLFLEMAAGQSMRQGG 171
Query: 113 LGVWKL-APMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTD 171
+GVWK+ AP GVG ++ ++ F L +Y+ V+ SW I+Y+ SF +PW++C N+
Sbjct: 172 MGVWKIIAPWIGGVGYSSFMVCFILGLYFNVVNSWIIFYMSQSFQFPVPWEKCPLTMNSS 231
Query: 172 RCFSNYSMVNTTNMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWK 231
T+ + FW + + +D ++ G + L + + W LV +
Sbjct: 232 ------GFDPECERTTPSIYFWYQQALKASDRIEDGGSPVYSLVLPFFLCWCLVGAFMIN 285
Query: 232 GVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDSEVWLDAATQ 291
G+ TGKV+Y P +++ F R + L GAK G+ + + + VW A Q
Sbjct: 286 GLKSTGKVIYVLVLLPCFIIVGFFIRTLLLEGAKFGLQQLVVAKISDVYNMSVWSLAGGQ 345
Query: 292 IFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCI-----------NSCTSMFAGFVIFS 340
+ + G+GLGS+ +L SY NN D+ +V I N C F VI
Sbjct: 346 VLSNTGIGLGSVASLASYMPQSNNCLSDAFLVSVINLLTLLVFTSFNFCVLGFWATVITH 405
Query: 341 ----------------------------------------IVGFMAHVTKRSIADV---- 356
+ G H+ + +V
Sbjct: 406 RCCERNAEILLKLINLGKLPPDAKPPVNLLYNPTSIYNAWLSGLPQHIKSMVLREVTECN 465
Query: 357 -------AASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALV 409
A+ GP AFL++ EA++ LP S W+ +FF MLL +G+ S ++G IT L
Sbjct: 466 IETQFLKASEGPKFAFLSFVEAMSFLPPSVFWSFIFFLMLLAMGLSSAIGIMQGIITPLQ 525
Query: 410 DEYPRLLRNRRELFIAAVCIISYLIGLSNITQGGIYVFKLF-DYYSASGMSLLFLVFFEC 468
D + R +L I V ++ ++ GL G Y +L DY+ ++ +V FE
Sbjct: 526 DTF-SFFRKHTKLLIVGVFLLMFVCGLFFTRPSGSYFIRLLSDYWIV--FPIIVVVVFET 582
Query: 469 VSISWFYGVNRFYDNIQEMVGS--RPCIWWKLCWSFFTPIIVAGVFIFSAVQ--MTPLTM 524
+++SW YG RF ++ ++G P W W P+++ +F+ V M P+T
Sbjct: 583 MAVSWAYGARRFLADLTILLGHPISPIFGW--LWPHLCPVVLLIIFVTMMVHLCMKPITY 640
Query: 525 GNY----------VFPKWGQGVGWLMALSSMVLIPGYMAY 554
++ +P W + + ++ IP Y Y
Sbjct: 641 MSWDSSTSKEVLRPYPPWALLLMITLFAIVILPIPAYFVY 680
>gi|226437581 solute carrier family 6, member 15 isoform 3 [Homo
sapiens]
Length = 623
Score = 198 bits (503), Expect = 1e-50
Identities = 95/256 (37%), Positives = 149/256 (58%), Gaps = 5/256 (1%)
Query: 94 GVPLFLLECSLGQYTSIGGLGVWK-LAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLY 152
G+PLF LE S+GQ G +GVW ++P G+G A+ V+ +++ +YY VII W+++Y
Sbjct: 4 GIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFS 63
Query: 153 NSFTTTLPWKQCDNPWNTDRCFSNYSMVNTTNMTSAVVEFWERNMHQMTDGLDKPGQIRW 212
SF LPW QC N F + +SA +W R ++ + + G + W
Sbjct: 64 QSFQQPLPWDQCPLVKNASHTF----VEPECEQSSATTYYWYREALNISSSISESGGLNW 119
Query: 213 PLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYI 272
+ I L AW++V + KG+ +GK++YFS+ +PY++LI R L G+ +GI
Sbjct: 120 KMTICLLAAWVMVCLAMIKGIQSSGKIIYFSSLFPYVVLICFLIRAFLLNGSIDGIRHMF 179
Query: 273 TPNFRKLSDSEVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSM 332
TP + + +VW +AATQ+FF+ GLG G +IA SYN NN + D+++V IN TS+
Sbjct: 180 TPKLEIMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSV 239
Query: 333 FAGFVIFSIVGFMAHV 348
A V+F+++GF A+V
Sbjct: 240 LATLVVFAVLGFKANV 255
Score = 125 bits (314), Expect = 1e-28
Identities = 57/163 (34%), Positives = 103/163 (63%), Gaps = 5/163 (3%)
Query: 357 AASGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLGIDSQFCTVEGFITALVDEYPRLL 416
A G GLAF+A+ EA+T P SP W+++FF ML+ LG+ S F T+EG +T +VD +
Sbjct: 328 AVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIEGIVTPIVDTF---- 383
Query: 417 RNRRELFIAAVCIISYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFECVSISWFYG 476
+ R+E+ C++++ IGL + + G Y +FD YSA+ + LL +V E +++ + YG
Sbjct: 384 KVRKEILTVICCLLAFCIGLIFVQRSGNYFVTMFDDYSAT-LPLLIVVILENIAVCFVYG 442
Query: 477 VNRFYDNIQEMVGSRPCIWWKLCWSFFTPIIVAGVFIFSAVQM 519
+++F +++++M+G P ++ W + +P+++ + I S V M
Sbjct: 443 IDKFMEDLKDMLGFAPSRYYYYMWKYISPLMLLSLLIASVVNM 485
>gi|197276625 solute carrier family 6 (neurotransmitter transporter,
taurine), member 6 isoform b [Homo sapiens]
Length = 200
Score = 188 bits (477), Expect = 1e-47
Identities = 84/162 (51%), Positives = 111/162 (68%), Gaps = 9/162 (5%)
Query: 42 PDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLE 101
P R+ W + DF++S G +GLGNVWRFPYLC KNGGGAFLIPYF+ L +G+P+F LE
Sbjct: 39 PQREKWSSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLE 98
Query: 102 CSLGQYTSIGGLGVW-KLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLP 160
+GQYTS GG+ W K+ P+F G+G A+ V+ LN+YYIVI++WA YYL+ SF LP
Sbjct: 99 IIIGQYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELP 158
Query: 161 WKQCDNPWNTDRCF--------SNYSMVNTTNMTSAVVEFWE 194
W C++ WNT C S + +++TN TS V+EFWE
Sbjct: 159 WAHCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWE 200
>gi|21361693 solute carrier family 6, member 15 isoform 2 [Homo
sapiens]
Length = 289
Score = 175 bits (444), Expect = 9e-44
Identities = 90/261 (34%), Positives = 142/261 (54%), Gaps = 10/261 (3%)
Query: 16 EVSEAPVANDKPKTLVVKVQKKAADLPDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCG 75
+ SE V + K V+ + D +R W + ++++ VG+++GLGNVWRFPYLC
Sbjct: 35 KTSELIVDGQEEKDTDVEEGSEVED--ERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQ 92
Query: 76 KNGGGAFLIPYFLTLIFAGVPLFLLECSLGQYTSIGGLGVWK-LAPMFKGVGLAAAVLSF 134
KNGGGA+L+PY + L+ G+PLF LE S+GQ G +GVW ++P G+G A+ V+ +
Sbjct: 93 KNGGGAYLLPYLILLMVIGIPLFFLELSVGQRIRRGSIGVWNYISPKLGGIGFASCVVCY 152
Query: 135 WLNIYYIVIISWAIYYLYNSFTTTLPWKQCDNPWNTDRCFSNYSMVNTTNMTSAVVEFWE 194
++ +YY VII W+++Y SF LPW QC N F + +SA +W
Sbjct: 153 FVALYYNVIIGWSLFYFSQSFQQPLPWDQCPLVKNASHTF----VEPECEQSSATTYYWY 208
Query: 195 RNMHQMTDGLDKPGQIRWPLAITLAIAWILVYFCIWKGVGWTGKVVYFSATYPYIMLIIL 254
R ++ + + G + W + I L AW++V + KG+ +GKV S P+++L+I
Sbjct: 209 REALNISSSISESGGLNWKMTICLLAAWVMVCLAMIKGIQSSGKV---SMLEPFLILLIT 265
Query: 255 FFRGVTLPGAKEGILFYITPN 275
+ L + IT N
Sbjct: 266 ISGFIPLSNSVTDFCGQITHN 286
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.141 0.461
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,056,834
Number of Sequences: 37866
Number of extensions: 951026
Number of successful extensions: 2542
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2389
Number of HSP's gapped (non-prelim): 54
length of query: 599
length of database: 18,247,518
effective HSP length: 108
effective length of query: 491
effective length of database: 14,157,990
effective search space: 6951573090
effective search space used: 6951573090
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.