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Search of human proteins with 187828357
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|187828357 SMAD family member 9 isoform a [Homo sapiens]
(467 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|187828357 SMAD family member 9 isoform a [Homo sapiens] 990 0.0
gi|5174519 SMAD family member 9 isoform b [Homo sapiens] 886 0.0
gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens] 783 0.0
gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens] 783 0.0
gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens] 765 0.0
gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens] 765 0.0
gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens] 765 0.0
gi|5174513 mothers against decapentaplegic homolog 3 isoform 1 [... 548 e-156
gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo sapi... 542 e-154
gi|51173730 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens] 526 e-149
gi|5174511 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens] 526 e-149
gi|223029442 mothers against decapentaplegic homolog 3 isoform 3... 472 e-133
gi|223029440 mothers against decapentaplegic homolog 3 isoform 2... 397 e-110
gi|223029444 mothers against decapentaplegic homolog 3 isoform 4... 335 4e-92
gi|4885457 mothers against decapentaplegic homolog 4 [Homo sapiens] 275 6e-74
gi|5174517 SMAD family member 7 [Homo sapiens] 100 4e-21
gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens] 97 2e-20
gi|218749837 SMAD family member 6 isoform 2 [Homo sapiens] 97 4e-20
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 42 0.002
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 42 0.002
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 42 0.002
gi|58530876 melanoma antigen family C, 1 [Homo sapiens] 39 0.008
gi|167234422 hematopoietic cell-specific Lyn substrate 1 [Homo s... 39 0.008
gi|4758666 LATS homolog 1 [Homo sapiens] 39 0.010
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 39 0.013
gi|189181750 human immunodeficiency virus type I enhancer bindin... 39 0.013
gi|116089331 human immunodeficiency virus type I enhancer bindin... 39 0.013
gi|38569460 SNF1-like kinase 2 [Homo sapiens] 38 0.017
gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens] 38 0.022
gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens] 38 0.022
>gi|187828357 SMAD family member 9 isoform a [Homo sapiens]
Length = 467
Score = 990 bits (2559), Expect = 0.0
Identities = 467/467 (100%), Positives = 467/467 (100%)
Query: 1 MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS 60
MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS
Sbjct: 1 MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS 60
Query: 61 CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK 120
CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK
Sbjct: 61 CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK 120
Query: 121 QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS 180
QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS
Sbjct: 121 QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS 180
Query: 181 FQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLPYHATEASETQ 240
FQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLPYHATEASETQ
Sbjct: 181 FQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLPYHATEASETQ 240
Query: 241 SGQPVDATADRHVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDG 300
SGQPVDATADRHVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDG
Sbjct: 241 SGQPVDATADRHVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDG 300
Query: 301 FTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSR 360
FTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSR
Sbjct: 301 FTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSR 360
Query: 361 NCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVK 420
NCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVK
Sbjct: 361 NCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVK 420
Query: 421 GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 467
GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS
Sbjct: 421 GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 467
>gi|5174519 SMAD family member 9 isoform b [Homo sapiens]
Length = 430
Score = 886 bits (2289), Expect = 0.0
Identities = 427/467 (91%), Positives = 428/467 (91%), Gaps = 37/467 (7%)
Query: 1 MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS 60
MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS
Sbjct: 1 MHSTTPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALS 60
Query: 61 CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK 120
CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK
Sbjct: 61 CPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSK 120
Query: 121 QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS 180
QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS
Sbjct: 121 QKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDS 180
Query: 181 FQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLPYHATEASETQ 240
FQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPES PY
Sbjct: 181 FQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPES-----------PYQ-------- 221
Query: 241 SGQPVDATADRHVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDG 300
+ DFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDG
Sbjct: 222 ------------------HSDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDG 263
Query: 301 FTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSR 360
FTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSR
Sbjct: 264 FTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSR 323
Query: 361 NCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVK 420
NCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVK
Sbjct: 324 NCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVK 383
Query: 421 GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 467
GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS
Sbjct: 384 GWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 430
>gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens]
Length = 465
Score = 783 bits (2021), Expect = 0.0
Identities = 379/465 (81%), Positives = 407/465 (87%), Gaps = 6/465 (1%)
Query: 7 ISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQPS 66
++SLFSFTSPAVKRLLGWKQGDEEEKWAEKAVD+LVKKLKKKKGAM+ELE+ALSCPGQPS
Sbjct: 3 VTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQPS 62
Query: 67 KCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCI 126
CVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCI
Sbjct: 63 NCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCI 122
Query: 127 NPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPC 186
NPYHY+RVE+PVLPPVLVPRHSEYNPQ SLLA+FR+ +EP MP NAT+PDSFQQP
Sbjct: 123 NPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLG-QNEPHMPLNATFPDSFQQPNS 181
Query: 187 SALPPSPSHAFSQSPCTAS--YPHSPGSPSEPESPYQHSVDTPPLPYHATEASETQSG-Q 243
P SP+ ++ SP ++S YPHSP S S+P SP+Q DTPP Y E TQ G Q
Sbjct: 182 HPFPHSPNSSYPNSPGSSSSTYPHSPTS-SDPGSPFQMPADTPPPAYLPPEDPMTQDGSQ 240
Query: 244 PVDATADRHVVLS-IPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFT 302
P+D + S I GD + V YEEP+HWCS+ YYELNNRVGE F ASS SVL+DGFT
Sbjct: 241 PMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT 300
Query: 303 DPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNC 362
DPSNN+NRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAEC+SDSSIFVQSRNC
Sbjct: 301 DPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC 360
Query: 363 NYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGW 422
NY HGFHP TVCKIPSGCSLK+FNNQ FAQLLAQSV+HGFE VYELTKMCTIRMSFVKGW
Sbjct: 361 NYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGW 420
Query: 423 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 467
GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS
Sbjct: 421 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
>gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens]
Length = 465
Score = 783 bits (2021), Expect = 0.0
Identities = 379/465 (81%), Positives = 407/465 (87%), Gaps = 6/465 (1%)
Query: 7 ISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQPS 66
++SLFSFTSPAVKRLLGWKQGDEEEKWAEKAVD+LVKKLKKKKGAM+ELE+ALSCPGQPS
Sbjct: 3 VTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQPS 62
Query: 67 KCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCI 126
CVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCI
Sbjct: 63 NCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCI 122
Query: 127 NPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPC 186
NPYHY+RVE+PVLPPVLVPRHSEYNPQ SLLA+FR+ +EP MP NAT+PDSFQQP
Sbjct: 123 NPYHYKRVESPVLPPVLVPRHSEYNPQHSLLAQFRNLG-QNEPHMPLNATFPDSFQQPNS 181
Query: 187 SALPPSPSHAFSQSPCTAS--YPHSPGSPSEPESPYQHSVDTPPLPYHATEASETQSG-Q 243
P SP+ ++ SP ++S YPHSP S S+P SP+Q DTPP Y E TQ G Q
Sbjct: 182 HPFPHSPNSSYPNSPGSSSSTYPHSPTS-SDPGSPFQMPADTPPPAYLPPEDPMTQDGSQ 240
Query: 244 PVDATADRHVVLS-IPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFT 302
P+D + S I GD + V YEEP+HWCS+ YYELNNRVGE F ASS SVL+DGFT
Sbjct: 241 PMDTNMMAPPLPSEINRGDVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT 300
Query: 303 DPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNC 362
DPSNN+NRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAEC+SDSSIFVQSRNC
Sbjct: 301 DPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNC 360
Query: 363 NYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGW 422
NY HGFHP TVCKIPSGCSLK+FNNQ FAQLLAQSV+HGFE VYELTKMCTIRMSFVKGW
Sbjct: 361 NYHHGFHPTTVCKIPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGW 420
Query: 423 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 467
GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS
Sbjct: 421 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 465
>gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens]
Length = 465
Score = 765 bits (1976), Expect = 0.0
Identities = 367/466 (78%), Positives = 407/466 (87%), Gaps = 5/466 (1%)
Query: 5 TPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQ 64
T ++SLFSFTSPAVKRLLGWKQGDEEEKWAEKAVD+LVKKLKKKKGAM+ELE+ALS PGQ
Sbjct: 2 TSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQ 61
Query: 65 PSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEV 124
PSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPL+ CEFPFGSKQKEV
Sbjct: 62 PSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEV 121
Query: 125 CINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQP 184
CINPYHY+RVE+PVLPPVLVPRH+E+NPQ SLL +FR+ S H+EP MP NAT+PDSF QP
Sbjct: 122 CINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLS-HNEPHMPQNATFPDSFHQP 180
Query: 185 PCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLPYHATEASETQ-SGQ 243
+ P SP+ + SP +++YP+SP S S P SP+Q DTPP Y + Q + Q
Sbjct: 181 NNTPFPLSPNSPYPPSPASSTYPNSPAS-SGPGSPFQLPADTPPPAYMPPDDQMGQDNSQ 239
Query: 244 PVDATADR--HVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGF 301
P+D + + ++ SI + D +PV YEEP+HWCS+ YYELNNRVGE F ASS SVL+DGF
Sbjct: 240 PMDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGF 299
Query: 302 TDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRN 361
TDPSNN++RFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAEC+SDSSIFVQSRN
Sbjct: 300 TDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRN 359
Query: 362 CNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKG 421
CN+ HGFHP TVCKIPS CSLK+FNNQ FAQLLAQSV+HGFE VYELTKMCTIRMSFVKG
Sbjct: 360 CNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKG 419
Query: 422 WGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 467
WGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSP NPISSVS
Sbjct: 420 WGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465
>gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens]
Length = 465
Score = 765 bits (1976), Expect = 0.0
Identities = 367/466 (78%), Positives = 407/466 (87%), Gaps = 5/466 (1%)
Query: 5 TPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQ 64
T ++SLFSFTSPAVKRLLGWKQGDEEEKWAEKAVD+LVKKLKKKKGAM+ELE+ALS PGQ
Sbjct: 2 TSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQ 61
Query: 65 PSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEV 124
PSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPL+ CEFPFGSKQKEV
Sbjct: 62 PSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEV 121
Query: 125 CINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQP 184
CINPYHY+RVE+PVLPPVLVPRH+E+NPQ SLL +FR+ S H+EP MP NAT+PDSF QP
Sbjct: 122 CINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLS-HNEPHMPQNATFPDSFHQP 180
Query: 185 PCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLPYHATEASETQ-SGQ 243
+ P SP+ + SP +++YP+SP S S P SP+Q DTPP Y + Q + Q
Sbjct: 181 NNTPFPLSPNSPYPPSPASSTYPNSPAS-SGPGSPFQLPADTPPPAYMPPDDQMGQDNSQ 239
Query: 244 PVDATADR--HVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGF 301
P+D + + ++ SI + D +PV YEEP+HWCS+ YYELNNRVGE F ASS SVL+DGF
Sbjct: 240 PMDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGF 299
Query: 302 TDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRN 361
TDPSNN++RFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAEC+SDSSIFVQSRN
Sbjct: 300 TDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRN 359
Query: 362 CNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKG 421
CN+ HGFHP TVCKIPS CSLK+FNNQ FAQLLAQSV+HGFE VYELTKMCTIRMSFVKG
Sbjct: 360 CNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKG 419
Query: 422 WGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 467
WGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSP NPISSVS
Sbjct: 420 WGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465
>gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens]
Length = 465
Score = 765 bits (1976), Expect = 0.0
Identities = 367/466 (78%), Positives = 407/466 (87%), Gaps = 5/466 (1%)
Query: 5 TPISSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQ 64
T ++SLFSFTSPAVKRLLGWKQGDEEEKWAEKAVD+LVKKLKKKKGAM+ELE+ALS PGQ
Sbjct: 2 TSMASLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQ 61
Query: 65 PSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEV 124
PSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPL+ CEFPFGSKQKEV
Sbjct: 62 PSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEV 121
Query: 125 CINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQP 184
CINPYHY+RVE+PVLPPVLVPRH+E+NPQ SLL +FR+ S H+EP MP NAT+PDSF QP
Sbjct: 122 CINPYHYKRVESPVLPPVLVPRHNEFNPQHSLLVQFRNLS-HNEPHMPQNATFPDSFHQP 180
Query: 185 PCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLPYHATEASETQ-SGQ 243
+ P SP+ + SP +++YP+SP S S P SP+Q DTPP Y + Q + Q
Sbjct: 181 NNTPFPLSPNSPYPPSPASSTYPNSPAS-SGPGSPFQLPADTPPPAYMPPDDQMGQDNSQ 239
Query: 244 PVDATADR--HVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGF 301
P+D + + ++ SI + D +PV YEEP+HWCS+ YYELNNRVGE F ASS SVL+DGF
Sbjct: 240 PMDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGF 299
Query: 302 TDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRN 361
TDPSNN++RFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAEC+SDSSIFVQSRN
Sbjct: 300 TDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRN 359
Query: 362 CNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKG 421
CN+ HGFHP TVCKIPS CSLK+FNNQ FAQLLAQSV+HGFE VYELTKMCTIRMSFVKG
Sbjct: 360 CNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKG 419
Query: 422 WGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 467
WGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSP NPISSVS
Sbjct: 420 WGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465
>gi|5174513 mothers against decapentaplegic homolog 3 isoform 1
[Homo sapiens]
Length = 425
Score = 548 bits (1411), Expect = e-156
Identities = 281/465 (60%), Positives = 335/465 (72%), Gaps = 44/465 (9%)
Query: 7 ISSLFSFTSPAVKRLLGWKQGDE---EEKWAEKAVDSLVKKLKKKKGAMDELERALSCPG 63
+SS+ FT P VKRLLGWK+G++ EEKW EKAV SLVKKLKK G +DELE+A++
Sbjct: 1 MSSILPFTPPIVKRLLGWKKGEQNGQEEKWCEKAVKSLVKKLKKT-GQLDELEKAITTQN 59
Query: 64 QPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKE 123
+KC+TIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ E
Sbjct: 60 VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDE 119
Query: 124 VCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQ 183
VC+NPYHY+RVETPVLPPVLVPRH+E + L + HS +P N +P +
Sbjct: 120 VCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYS----HS---IPENTNFPAGIE- 171
Query: 184 PPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLPYHATEA-SETQSG 242
P S +P +P PG SE H ++ H+ +A S S
Sbjct: 172 -PQSNIPETPP---------------PGYLSEDGETSDHQMN------HSMDAGSPNLSP 209
Query: 243 QPVDATADRHVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFT 302
P+ + N D +PV Y EP WCS++YYELN RVGETF AS S+ +DGFT
Sbjct: 210 NPMSPAHN--------NLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFT 261
Query: 303 DPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNC 362
DPSN+ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AEC+SDS+IFVQS NC
Sbjct: 262 DPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNC 320
Query: 363 NYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGW 422
N ++G+HPATVCKIP GC+LK+FNNQ FA LLAQSV+ GFE VY+LT+MCTIRMSFVKGW
Sbjct: 321 NQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGW 380
Query: 423 GAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 467
GAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct: 381 GAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425
>gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo
sapiens]
Length = 437
Score = 542 bits (1397), Expect = e-154
Identities = 282/474 (59%), Positives = 333/474 (70%), Gaps = 50/474 (10%)
Query: 7 ISSLFSFTSPAVKRLLGWK-------------QGDEEEKWAEKAVDSLVKKLKKKKGAMD 53
+SS+ FT P VKRLLGWK Q +EEKW EKAV SLVKKLKK G +D
Sbjct: 1 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKT-GRLD 59
Query: 54 ELERALSCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECC 113
ELE+A++ +KCVTIPRSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHELK +E C
Sbjct: 60 ELEKAITTQNCNTKCVTIPRSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENC 119
Query: 114 EFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPH 173
E+ F K+ EVC+NPYHY+RVETPVLPPVLVPRH+E +L L + HS +P
Sbjct: 120 EYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYT----HS---IPE 172
Query: 174 NATYPDSFQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLPYHA 233
N +P + P + +P +P PG SE D
Sbjct: 173 NTNFPAGIE-PQSNYIPETPP---------------PGYISE---------DGETSDQQL 207
Query: 234 TEASETQSGQPVDATADRHVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASS 293
++ +T S + T V S+ D +PV Y EP WCS+AYYELN RVGETF AS
Sbjct: 208 NQSMDTGSPAELSPTTLSPVNHSL---DLQPVTYSEPAFWCSIAYYELNQRVGETFHASQ 264
Query: 294 RSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDS 353
S+ +DGFTDPSN+ RFCLGLLSNVNRN+T+E TRRHIG+GV LYY+GGEV+AEC+SDS
Sbjct: 265 PSLTVDGFTDPSNSE-RFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDS 323
Query: 354 SIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCT 413
+IFVQS NCN ++G+HPATVCKIP GC+LK+FNNQ FA LLAQSV+ GFE VY+LT+MCT
Sbjct: 324 AIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCT 383
Query: 414 IRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 467
IRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SS+S
Sbjct: 384 IRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSVRCSSMS 437
>gi|51173730 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]
Length = 467
Score = 526 bits (1356), Expect = e-149
Identities = 282/504 (55%), Positives = 333/504 (66%), Gaps = 80/504 (15%)
Query: 7 ISSLFSFTSPAVKRLLGWK-------------QGDEEEKWAEKAVDSLVKKLKKKKGAMD 53
+SS+ FT P VKRLLGWK Q +EEKW EKAV SLVKKLKK G +D
Sbjct: 1 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKT-GRLD 59
Query: 54 ELERALSCPGQPSKCVTIP------------------------------RSLDGRLQVSH 83
ELE+A++ +KCVTIP RSLDGRLQVSH
Sbjct: 60 ELEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSH 119
Query: 84 RKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVETPVLPPVL 143
RKGLPHVIYCR+WRWPDL SHHELK +E CE+ F K+ EVC+NPYHY+RVETPVLPPVL
Sbjct: 120 RKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVL 179
Query: 144 VPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPPSPSHAFSQSPCT 203
VPRH+E +L L + HS +P N +P + P + +P +P
Sbjct: 180 VPRHTEILTELPPLDDYT----HS---IPENTNFPAGIE-PQSNYIPETPP--------- 222
Query: 204 ASYPHSPGSPSEPESPYQHSVDTPPLPYHATEASETQSGQPVDATADRHVVLSIPNGDFR 263
PG SE D ++ +T S + T V S+ D +
Sbjct: 223 ------PGYISE---------DGETSDQQLNQSMDTGSPAELSPTTLSPVNHSL---DLQ 264
Query: 264 PVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNS 323
PV Y EP WCS+AYYELN RVGETF AS S+ +DGFTDPSN+ RFCLGLLSNVNRN+
Sbjct: 265 PVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSE-RFCLGLLSNVNRNA 323
Query: 324 TIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLK 383
T+E TRRHIG+GV LYY+GGEV+AEC+SDS+IFVQS NCN ++G+HPATVCKIP GC+LK
Sbjct: 324 TVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLK 383
Query: 384 VFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLH 443
+FNNQ FA LLAQSV+ GFE VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+
Sbjct: 384 IFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLN 443
Query: 444 GPLQWLDKVLTQMGSPHNPISSVS 467
GPLQWLDKVLTQMGSP SS+S
Sbjct: 444 GPLQWLDKVLTQMGSPSVRCSSMS 467
>gi|5174511 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]
Length = 467
Score = 526 bits (1356), Expect = e-149
Identities = 282/504 (55%), Positives = 333/504 (66%), Gaps = 80/504 (15%)
Query: 7 ISSLFSFTSPAVKRLLGWK-------------QGDEEEKWAEKAVDSLVKKLKKKKGAMD 53
+SS+ FT P VKRLLGWK Q +EEKW EKAV SLVKKLKK G +D
Sbjct: 1 MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKT-GRLD 59
Query: 54 ELERALSCPGQPSKCVTIP------------------------------RSLDGRLQVSH 83
ELE+A++ +KCVTIP RSLDGRLQVSH
Sbjct: 60 ELEKAITTQNCNTKCVTIPSTCSEIWGLSTPNTIDQWDTTGLYSFSEQTRSLDGRLQVSH 119
Query: 84 RKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVETPVLPPVL 143
RKGLPHVIYCR+WRWPDL SHHELK +E CE+ F K+ EVC+NPYHY+RVETPVLPPVL
Sbjct: 120 RKGLPHVIYCRLWRWPDLHSHHELKAIENCEYAFNLKKDEVCVNPYHYQRVETPVLPPVL 179
Query: 144 VPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPPSPSHAFSQSPCT 203
VPRH+E +L L + HS +P N +P + P + +P +P
Sbjct: 180 VPRHTEILTELPPLDDYT----HS---IPENTNFPAGIE-PQSNYIPETPP--------- 222
Query: 204 ASYPHSPGSPSEPESPYQHSVDTPPLPYHATEASETQSGQPVDATADRHVVLSIPNGDFR 263
PG SE D ++ +T S + T V S+ D +
Sbjct: 223 ------PGYISE---------DGETSDQQLNQSMDTGSPAELSPTTLSPVNHSL---DLQ 264
Query: 264 PVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNS 323
PV Y EP WCS+AYYELN RVGETF AS S+ +DGFTDPSN+ RFCLGLLSNVNRN+
Sbjct: 265 PVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSE-RFCLGLLSNVNRNA 323
Query: 324 TIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLK 383
T+E TRRHIG+GV LYY+GGEV+AEC+SDS+IFVQS NCN ++G+HPATVCKIP GC+LK
Sbjct: 324 TVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLK 383
Query: 384 VFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLH 443
+FNNQ FA LLAQSV+ GFE VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+
Sbjct: 384 IFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLN 443
Query: 444 GPLQWLDKVLTQMGSPHNPISSVS 467
GPLQWLDKVLTQMGSP SS+S
Sbjct: 444 GPLQWLDKVLTQMGSPSVRCSSMS 467
>gi|223029442 mothers against decapentaplegic homolog 3 isoform 3
[Homo sapiens]
Length = 381
Score = 472 bits (1214), Expect = e-133
Identities = 240/396 (60%), Positives = 283/396 (71%), Gaps = 40/396 (10%)
Query: 73 RSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYR 132
RSLDGRLQVSHRKGLPHVIYCR+WRWPDL SHHEL+ +E CEF F K+ EVC+NPYHY+
Sbjct: 25 RSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCEFAFNMKKDEVCVNPYHYQ 84
Query: 133 RVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPPS 192
RVETPVLPPVLVPRH+E + L + HS +P N +P + P S +P +
Sbjct: 85 RVETPVLPPVLVPRHTEIPAEFPPLDDYS----HS---IPENTNFPAGIE--PQSNIPET 135
Query: 193 PSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLPYHATEA-SETQSGQPVDATADR 251
P PG SE H ++ H+ +A S S P+ +
Sbjct: 136 PP---------------PGYLSEDGETSDHQMN------HSMDAGSPNLSPNPMSPAHN- 173
Query: 252 HVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRF 311
N D +PV Y EP WCS++YYELN RVGETF AS S+ +DGFTDPSN+ RF
Sbjct: 174 -------NLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSE-RF 225
Query: 312 CLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPA 371
CLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AEC+SDS+IFVQS NCN ++G+HPA
Sbjct: 226 CLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPA 285
Query: 372 TVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDV 431
TVCKIP GC+LK+FNNQ FA LLAQSV+ GFE VY+LT+MCTIRMSFVKGWGAEY RQ V
Sbjct: 286 TVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTV 345
Query: 432 TSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 467
TSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct: 346 TSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 381
>gi|223029440 mothers against decapentaplegic homolog 3 isoform 2
[Homo sapiens]
Length = 320
Score = 397 bits (1020), Expect = e-110
Identities = 207/359 (57%), Positives = 248/359 (69%), Gaps = 40/359 (11%)
Query: 110 LECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEP 169
+E CEF F K+ EVC+NPYHY+RVETPVLPPVLVPRH+E + L + HS
Sbjct: 1 MELCEFAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPAEFPPLDDYS----HS-- 54
Query: 170 LMPHNATYPDSFQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPL 229
+P N +P + P S +P +P PG SE H ++
Sbjct: 55 -IPENTNFPAGIE--PQSNIPETPP---------------PGYLSEDGETSDHQMN---- 92
Query: 230 PYHATEA-SETQSGQPVDATADRHVVLSIPNGDFRPVCYEEPQHWCSVAYYELNNRVGET 288
H+ +A S S P+ + N D +PV Y EP WCS++YYELN RVGET
Sbjct: 93 --HSMDAGSPNLSPNPMSPAHN--------NLDLQPVTYCEPAFWCSISYYELNQRVGET 142
Query: 289 FQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAE 348
F AS S+ +DGFTDPSN+ RFCLGLLSNVNRN+ +E TRRHIG+GV LYY+GGEV+AE
Sbjct: 143 FHASQPSMTVDGFTDPSNSE-RFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAE 201
Query: 349 CVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYEL 408
C+SDS+IFVQS NCN ++G+HPATVCKIP GC+LK+FNNQ FA LLAQSV+ GFE VY+L
Sbjct: 202 CLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQL 261
Query: 409 TKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 467
T+MCTIRMSFVKGWGAEY RQ VTSTPCWIE+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct: 262 TRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 320
>gi|223029444 mothers against decapentaplegic homolog 3 isoform 4
[Homo sapiens]
Length = 230
Score = 335 bits (860), Expect = 4e-92
Identities = 157/209 (75%), Positives = 180/209 (86%), Gaps = 1/209 (0%)
Query: 259 NGDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSN 318
N D +PV Y EP WCS++YYELN RVGETF AS S+ +DGFTDPSN+ RFCLGLLSN
Sbjct: 23 NLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSE-RFCLGLLSN 81
Query: 319 VNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPS 378
VNRN+ +E TRRHIG+GV LYY+GGEV+AEC+SDS+IFVQS NCN ++G+HPATVCKIP
Sbjct: 82 VNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPP 141
Query: 379 GCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWI 438
GC+LK+FNNQ FA LLAQSV+ GFE VY+LT+MCTIRMSFVKGWGAEY RQ VTSTPCWI
Sbjct: 142 GCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWI 201
Query: 439 EIHLHGPLQWLDKVLTQMGSPHNPISSVS 467
E+HL+GPLQWLDKVLTQMGSP SSVS
Sbjct: 202 ELHLNGPLQWLDKVLTQMGSPSIRCSSVS 230
>gi|4885457 mothers against decapentaplegic homolog 4 [Homo sapiens]
Length = 552
Score = 275 bits (703), Expect = 6e-74
Identities = 193/534 (36%), Positives = 265/534 (49%), Gaps = 105/534 (19%)
Query: 18 VKRLLGWKQGDEEEKWAEKAVDSLVKKLKKKKGAMDELERALSCPG-QPSKCVTIPRSLD 76
V L+ +QG E E +A++A++SLVKKLK+KK +D L A++ G PSKCVTI R+LD
Sbjct: 20 VHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLD 79
Query: 77 GRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVET 136
GRLQV+ RKG PHVIY R+WRWPDL +ELK ++ C++ F K VC+NPYHY RV +
Sbjct: 80 GRLQVAGRKGFPHVIYARLWRWPDLHK-NELKHVKYCQYAFDLKCDSVCVNPYHYERVVS 138
Query: 137 PVL-----------PPVLVPRHS---EYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQ 182
P + P ++ + ++ Q SL + S P P N +++
Sbjct: 139 PGIDLSGLTLQSNAPSSMMVKDEYVHDFEGQPSLSTEGHSIQTIQHP--PSNRASTETYS 196
Query: 183 QPPCSALPPSPSHAFSQSPCTASYPHSP-GSPSEPES--------------------PYQ 221
P + L PS S+A S TA++P+ P S S+P S Q
Sbjct: 197 TP--ALLAPSESNATS----TANFPNIPVASTSQPASILGGSHSEGLLQIASGPQPGQQQ 250
Query: 222 HSVDTPPLPYHATEASETQSGQPVDATAD----------RHVVLSIPNGDFRPVCYE--- 268
+ P YH + + T + H + G + PV E
Sbjct: 251 NGFTGQPATYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPPMPPHPGHYWPVHNELAF 310
Query: 269 --------EPQHWCSVAYYELNNRVGETFQASSRS--VLIDGFTDPSNNRNRFCLGLLSN 318
P++WCS+AY+E++ +VGETF+ S V +DG+ DPS +RFCLG LSN
Sbjct: 311 QPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGG-DRFCLGQLSN 369
Query: 319 VNRNSTIENTRRHIGKGVHLYYVG-GEVYAECVSDSSIFVQSRNCNYQHGFHPA-TVCKI 376
V+R IE R HIGKGV L G G+V+ C+SD ++FVQS + + G P V KI
Sbjct: 370 VHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKI 429
Query: 377 PSGCSLKVFN--------NQLFAQLLAQSVHHGFEV------------------------ 404
+KVF+ Q A A + V
Sbjct: 430 YPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAAAG 489
Query: 405 --VYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQM 456
V +L ++C +RMSFVKGWG +Y RQ + TPCWIEIHLH LQ LD+VL M
Sbjct: 490 IGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 543
>gi|5174517 SMAD family member 7 [Homo sapiens]
Length = 426
Score = 100 bits (248), Expect = 4e-21
Identities = 110/412 (26%), Positives = 163/412 (39%), Gaps = 99/412 (24%)
Query: 40 SLVKKLKKKKGAMDELERALSCPGQPSKCVTIPRSLDGRL-----------QVSHRKGLP 88
S++KKLK+++ + L+ S G + C+ +P LD RL Q LP
Sbjct: 98 SVLKKLKERQLEL-LLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLP 156
Query: 89 HVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHS 148
++ C+V+RWPDL+ E+K L CCE + VC N P H
Sbjct: 157 -LLLCKVFRWPDLRHSSEVKRLCCCESYGKINPELVCCN-----------------PHHL 198
Query: 149 EYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPPSPSHAFSQSPCTASYPH 208
R L S P P + YP F +P PS A + +Y
Sbjct: 199 S-----------RLCELESPP--PPYSRYPMDFLKPTADCPDAVPSSAETGG---TNYL- 241
Query: 209 SPGSPSEPESPYQHSVDTPPLPYHATEASETQSGQPVDATADRHVVLSIPNGDFRPVCYE 268
+PG S+ + L + GD
Sbjct: 242 APGGLSDSQ-------------------------------------LLLEPGD------- 257
Query: 269 EPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENT 328
HWC VAY+E RVG + S +D F D N FCLG L++ N++ ++
Sbjct: 258 -RSHWCVVAYWEEKTRVGRLYCVQEPS--LDIFYDLPQG-NGFCLGQLNSDNKSQLVQKV 313
Query: 329 RRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQ 388
R IG G+ L V+ S IF++S + V K+ G S+K F+ +
Sbjct: 314 RSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDS-RTLLVHKVFPGFSIKAFDYE 372
Query: 389 LFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEI 440
L + H E + + T+++SFVKGWG Y RQ ++S PCW+E+
Sbjct: 373 KAYSLQRPNDH---EFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLEV 421
>gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens]
Length = 496
Score = 97.4 bits (241), Expect = 2e-20
Identities = 84/274 (30%), Positives = 124/274 (45%), Gaps = 30/274 (10%)
Query: 191 PSPSHAFSQSPCTA--SYPHSPGSPSEPESPYQHS----VDTPPLPYHATEASETQSGQP 244
P HA P S+ + P+ +PY S ++PP PY + S +P
Sbjct: 233 PDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPY--SRLSPRDEYKP 290
Query: 245 VDA---------TADRHVVLSIPNGDFRPVCYE----EPQHWCSVAYYELNNRVGETFQA 291
+D T + +++ P G+F +P HWCSVAY+E RVG +
Sbjct: 291 LDLSDSTLSYTETEATNSLITAP-GEFSDASMSPDATKPSHWCSVAYWEHRTRVGRLYAV 349
Query: 292 SSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVS 351
++V I F D FCLG L+ R+ ++ TR IG G+ L V+A
Sbjct: 350 YDQAVSI--FYDLPQGSG-FCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRG 406
Query: 352 DSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKM 411
+ IFV S + G V K+P G S+KVF+ + + L + Y+
Sbjct: 407 EHPIFVNSPTLDAPGG-RALVVRKVPPGYSIKVFDFER-SGLQHAPEPDAADGPYDPN-- 462
Query: 412 CTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGP 445
++R+SF KGWG Y RQ +TS PCW+EI L+ P
Sbjct: 463 -SVRISFAKGWGPCYSRQFITSCPCWLEILLNNP 495
Score = 67.4 bits (163), Expect = 3e-11
Identities = 44/116 (37%), Positives = 66/116 (56%), Gaps = 10/116 (8%)
Query: 40 SLVKKLKKKKGAMDELERAL-SCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRW 98
SL+K+LK++ ++D L A+ S G P CV +PR+ L++ + P ++ R++RW
Sbjct: 178 SLLKRLKER--SLDTLLEAVESRGGVPGGCVLVPRA---DLRLGGQPAPPQLLLGRLFRW 232
Query: 99 PDLQSHHELKPL-ECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQ 153
PDLQ ELKPL C F + VC NPYH+ R+ P PP P +S +P+
Sbjct: 233 PDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPP---PPYSRLSPR 285
>gi|218749837 SMAD family member 6 isoform 2 [Homo sapiens]
Length = 235
Score = 96.7 bits (239), Expect = 4e-20
Identities = 80/242 (33%), Positives = 111/242 (45%), Gaps = 27/242 (11%)
Query: 207 PHSPGSPSEPESPYQHSVDTPPLPYHATEASE---TQSGQPVDATADRHVVLSIPNGDFR 263
P+S SP + P S T L Y TEA+ T G+ DA+
Sbjct: 17 PYSRLSPRDEYKPLDLSDST--LSYTETEATNSLITAPGEFSDASMSPDAT--------- 65
Query: 264 PVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNS 323
+P HWCSVAY+E RVG + ++V I F D FCLG L+ R+
Sbjct: 66 -----KPSHWCSVAYWEHRTRVGRLYAVYDQAVSI--FYDLPQGSG-FCLGQLNLEQRSE 117
Query: 324 TIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPATVCKIPSGCSLK 383
++ TR IG G+ L V+A + IFV S + G V K+P G S+K
Sbjct: 118 SVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPGG-RALVVRKVPPGYSIK 176
Query: 384 VFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLH 443
VF+ + + L + Y+ ++R+SF KGWG Y RQ +TS PCW+EI L+
Sbjct: 177 VFDFER-SGLQHAPEPDAADGPYDPN---SVRISFAKGWGPCYSRQFITSCPCWLEILLN 232
Query: 444 GP 445
P
Sbjct: 233 NP 234
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 41.6 bits (96), Expect = 0.002
Identities = 31/97 (31%), Positives = 38/97 (39%), Gaps = 11/97 (11%)
Query: 140 PPVLVPRHS--------EYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPP 191
PP L P S + P L L+ + S L S P P T + PP S PP
Sbjct: 412 PPALKPLSSLSTHHPPSAHPPPLQLMPQ--SQPLPSSPAQPPGLTQSQNLPPPPASH-PP 468
Query: 192 SPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPP 228
+ H + P A +P PG P P S TPP
Sbjct: 469 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPP 505
Score = 29.6 bits (65), Expect = 6.1
Identities = 22/73 (30%), Positives = 27/73 (36%), Gaps = 16/73 (21%)
Query: 178 PDSFQQPPCSALPPSPSHAFSQSPCT-------------ASYPHSPGSPSEPESPYQHSV 224
P + QPPCS S S C A P SP P SP V
Sbjct: 508 PGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVV 567
Query: 225 DTPPLPYHATEAS 237
DTP HA++++
Sbjct: 568 DTPS---HASQSA 577
Score = 29.3 bits (64), Expect = 8.0
Identities = 26/92 (28%), Positives = 32/92 (34%), Gaps = 11/92 (11%)
Query: 172 PHNATYPDSFQQPPCSALPPSPSHAFSQSP-----CTASYPH-----SPG-SPSEPESPY 220
P P P +A+PP S SQ+P TA PH +P P P SP+
Sbjct: 202 PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 261
Query: 221 QHSVDTPPLPYHATEASETQSGQPVDATADRH 252
+P P S Q P A H
Sbjct: 262 PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLH 293
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 41.6 bits (96), Expect = 0.002
Identities = 31/97 (31%), Positives = 38/97 (39%), Gaps = 11/97 (11%)
Query: 140 PPVLVPRHS--------EYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPP 191
PP L P S + P L L+ + S L S P P T + PP S PP
Sbjct: 966 PPALKPLSSLSTHHPPSAHPPPLQLMPQ--SQPLPSSPAQPPGLTQSQNLPPPPASH-PP 1022
Query: 192 SPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPP 228
+ H + P A +P PG P P S TPP
Sbjct: 1023 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPP 1059
Score = 29.6 bits (65), Expect = 6.1
Identities = 22/73 (30%), Positives = 27/73 (36%), Gaps = 16/73 (21%)
Query: 178 PDSFQQPPCSALPPSPSHAFSQSPCT-------------ASYPHSPGSPSEPESPYQHSV 224
P + QPPCS S S C A P SP P SP V
Sbjct: 1062 PGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVV 1121
Query: 225 DTPPLPYHATEAS 237
DTP HA++++
Sbjct: 1122 DTPS---HASQSA 1131
Score = 29.3 bits (64), Expect = 8.0
Identities = 26/92 (28%), Positives = 32/92 (34%), Gaps = 11/92 (11%)
Query: 172 PHNATYPDSFQQPPCSALPPSPSHAFSQSP-----CTASYPH-----SPG-SPSEPESPY 220
P P P +A+PP S SQ+P TA PH +P P P SP+
Sbjct: 756 PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 815
Query: 221 QHSVDTPPLPYHATEASETQSGQPVDATADRH 252
+P P S Q P A H
Sbjct: 816 PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLH 847
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 41.6 bits (96), Expect = 0.002
Identities = 31/97 (31%), Positives = 38/97 (39%), Gaps = 11/97 (11%)
Query: 140 PPVLVPRHS--------EYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPP 191
PP L P S + P L L+ + S L S P P T + PP S PP
Sbjct: 966 PPALKPLSSLSTHHPPSAHPPPLQLMPQ--SQPLPSSPAQPPGLTQSQNLPPPPASH-PP 1022
Query: 192 SPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPP 228
+ H + P A +P PG P P S TPP
Sbjct: 1023 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPP 1059
Score = 29.6 bits (65), Expect = 6.1
Identities = 22/73 (30%), Positives = 27/73 (36%), Gaps = 16/73 (21%)
Query: 178 PDSFQQPPCSALPPSPSHAFSQSPCT-------------ASYPHSPGSPSEPESPYQHSV 224
P + QPPCS S S C A P SP P SP V
Sbjct: 1062 PGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVV 1121
Query: 225 DTPPLPYHATEAS 237
DTP HA++++
Sbjct: 1122 DTPS---HASQSA 1131
Score = 29.3 bits (64), Expect = 8.0
Identities = 26/92 (28%), Positives = 32/92 (34%), Gaps = 11/92 (11%)
Query: 172 PHNATYPDSFQQPPCSALPPSPSHAFSQSP-----CTASYPH-----SPG-SPSEPESPY 220
P P P +A+PP S SQ+P TA PH +P P P SP+
Sbjct: 756 PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 815
Query: 221 QHSVDTPPLPYHATEASETQSGQPVDATADRH 252
+P P S Q P A H
Sbjct: 816 PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLH 847
>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
Length = 1142
Score = 39.3 bits (90), Expect = 0.008
Identities = 39/119 (32%), Positives = 49/119 (41%), Gaps = 10/119 (8%)
Query: 135 ETPVLPPVLVPRHSEYNPQLSLLAKFRSASL----HSEPLMPHNATYPDSFQQPPCSALP 190
E+P PP P S +S + ASL H P P Q P S+ P
Sbjct: 761 ESPQSPPE-GPAQSPLQRPVSSFFSYTLASLLQSSHESPQSPPEGPAQSPLQSP-VSSFP 818
Query: 191 PSPSHAFSQSPCTASYPHSPG---SPSEPESPYQHSVDTPPLPYHATEASETQSGQPVD 246
S S + SQS +S+P S S S PESP Q V + + SE +S PVD
Sbjct: 819 SSTSSSLSQSSPVSSFPSSTSSSLSKSSPESPLQSPVISFSSSTSLSPFSE-ESSSPVD 876
Score = 35.0 bits (79), Expect = 0.15
Identities = 34/144 (23%), Positives = 55/144 (38%), Gaps = 21/144 (14%)
Query: 110 LECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEP 169
L FP + E ++P H+ P PP S +S+ + S SL
Sbjct: 705 LSSLHFPQSPPEWEDSLSPLHF-----PQFPPQGEDFQSSLQSPVSICSSSTSLSLPQ-- 757
Query: 170 LMPHNATYPDSFQQPPCSAL------PPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHS 223
++P+S Q PP P S +++ + S SP SP PE P Q
Sbjct: 758 ------SFPESPQSPPEGPAQSPLQRPVSSFFSYTLASLLQSSHESPQSP--PEGPAQSP 809
Query: 224 VDTPPLPYHATEASETQSGQPVDA 247
+ +P + ++ +S PV +
Sbjct: 810 LQSPVSSFPSSTSSSLSQSSPVSS 833
Score = 32.0 bits (71), Expect = 1.2
Identities = 43/159 (27%), Positives = 55/159 (34%), Gaps = 26/159 (16%)
Query: 98 WPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLL 157
W D S H FP Q E ++P HY P L P + +PQ
Sbjct: 539 WEDSLSPHY--------FPQSPPQGEDSLSP-HYFPQSPPQGEDSLSPHYFPQSPQGE-- 587
Query: 158 AKFRSASLHSEPLMP---HNATYPDSFQQPPCSALPPSPSHAFSQSPCTASYPHS----- 209
S S H P P ++ P F Q P S S C++S P S
Sbjct: 588 ---DSLSPHYFPQSPPQGEDSMSPLYFPQSPLQGEEFQSSLQSPVSICSSSTPSSLPQSF 644
Query: 210 -PGSPSEPESPYQ---HSVDTPPLPYHATEASETQSGQP 244
S S PE P Q HS +PP H+ ++ P
Sbjct: 645 PESSQSPPEGPVQSPLHSPQSPPEGMHSQSPLQSPESAP 683
>gi|167234422 hematopoietic cell-specific Lyn substrate 1 [Homo
sapiens]
Length = 486
Score = 39.3 bits (90), Expect = 0.008
Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 12/93 (12%)
Query: 132 RRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPP 191
+++ + PPV P SE P R++ H PL+P T P+ ++PP ALPP
Sbjct: 296 KKISSEAWPPVGTPPSSESEP-------VRTSREHPVPLLPIRQTLPEDNEEPP--ALPP 346
Query: 192 SPSHAF--SQSPCTASYPHSPGSPS-EPESPYQ 221
+ P + P P EPE+ Y+
Sbjct: 347 RTLEGLQVEEEPVYEAEPEPEPEPEPEPENDYE 379
>gi|4758666 LATS homolog 1 [Homo sapiens]
Length = 1130
Score = 38.9 bits (89), Expect = 0.010
Identities = 32/119 (26%), Positives = 46/119 (38%), Gaps = 9/119 (7%)
Query: 128 PYHYRRVETPVLPPVLVPRHSEYNPQLSLLAK---FRSASLHSEPLMPHNATYPDSFQQP 184
P RV P L L P H + PQ + F + + +MP A P+ +Q P
Sbjct: 497 PVKSMRVLKPELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNVTVMPPVAEAPN-YQGP 555
Query: 185 PCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLPYHATEASETQSGQ 243
P PP P H Q+P Y S PS+ + P D Y ++ + + Q
Sbjct: 556 P----PPYPKHLLHQNPSVPPY-ESISKPSKEDQPSLPKEDESEKSYENVDSGDKEKKQ 609
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 38.5 bits (88), Expect = 0.013
Identities = 26/83 (31%), Positives = 33/83 (39%), Gaps = 2/83 (2%)
Query: 164 SLHSEPL-MPHNATYPDSFQQPPCSALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQH 222
S+HS +P YP +F Q + +PPSP H T P P P+ P P
Sbjct: 898 SIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVLP 957
Query: 223 SVDTPPLPYHATEASETQSGQPV 245
T P P T+ QPV
Sbjct: 958 PQPTLP-PQPVLPPQPTRPPQPV 979
Score = 30.8 bits (68), Expect = 2.7
Identities = 27/103 (26%), Positives = 37/103 (35%), Gaps = 7/103 (6%)
Query: 137 PVLPPV-LVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPPSPSH 195
P LPP +P PQ +L + L +P P P PP LPP P+
Sbjct: 942 PALPPQPTLPPQPVLPPQPTLPPQ---PVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPAL 998
Query: 196 AFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLPYHATEASE 238
P PH P + +P + P PY A++
Sbjct: 999 PVRPEPL---QPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQ 1038
Score = 30.4 bits (67), Expect = 3.6
Identities = 30/95 (31%), Positives = 34/95 (35%), Gaps = 14/95 (14%)
Query: 134 VETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPCSALPPSP 193
V +P LP VL+P E PQ SAS+ S P P A PP P
Sbjct: 1049 VLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPP---------ANPPLP 1099
Query: 194 SHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPP 228
SPC + EP Q S D PP
Sbjct: 1100 GGPGIASPCP-----TVQLTVEPVQEEQASQDKPP 1129
>gi|189181750 human immunodeficiency virus type I enhancer binding
protein 3 b [Homo sapiens]
Length = 2405
Score = 38.5 bits (88), Expect = 0.013
Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 11/74 (14%)
Query: 145 PRHSEYNPQLSLLAKFRSASLHSEPLMPHNA-TYPD----SFQQPPCSALPPSP---SHA 196
PR S + + S+ + +SL+ EPL H+ T P+ S Q PP +A PP P SH+
Sbjct: 486 PRRSSLSRRSSMESP--KSSLYREPLSSHSEKTKPEQSLLSLQHPPSTA-PPVPLLRSHS 542
Query: 197 FSQSPCTASYPHSP 210
+ CT S PH P
Sbjct: 543 MPSAACTISTPHHP 556
>gi|116089331 human immunodeficiency virus type I enhancer binding
protein 3 [Homo sapiens]
Length = 2406
Score = 38.5 bits (88), Expect = 0.013
Identities = 28/74 (37%), Positives = 39/74 (52%), Gaps = 11/74 (14%)
Query: 145 PRHSEYNPQLSLLAKFRSASLHSEPLMPHNA-TYPD----SFQQPPCSALPPSP---SHA 196
PR S + + S+ + +SL+ EPL H+ T P+ S Q PP +A PP P SH+
Sbjct: 486 PRRSSLSRRSSMESP--KSSLYREPLSSHSEKTKPEQSLLSLQHPPSTA-PPVPLLRSHS 542
Query: 197 FSQSPCTASYPHSP 210
+ CT S PH P
Sbjct: 543 MPSAACTISTPHHP 556
>gi|38569460 SNF1-like kinase 2 [Homo sapiens]
Length = 926
Score = 38.1 bits (87), Expect = 0.017
Identities = 60/224 (26%), Positives = 83/224 (37%), Gaps = 31/224 (13%)
Query: 68 CVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCIN 127
C PRSL+ +LQ HR + + + LQ++ + +P S+Q +
Sbjct: 701 CKEPPRSLEQQLQ-EHRLQQKRLF---LQKQSQLQAYFNQMQIAESSYPQPSQQLPL--- 753
Query: 128 PYHYRRVETPVLPPVLVPRHSEYNPQLSL---LAKFRSASLHSEPLMPHNATYPDSFQQP 184
R ETP PP S+ P SL L+ S P + Y + QP
Sbjct: 754 ----PRQETP--PP------SQQAPPFSLTQPLSPVLEPSSEQMQYSPFLSQYQEMQLQP 801
Query: 185 PCS-----ALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLPYHATEASE- 238
S A PP P+ Q P P P P +P Q S T LP A+ A +
Sbjct: 802 LPSTSGPRAAPPLPTQLQQQQPPPPPPPPPPRQPGAAPAPLQFSYQTCELPSAASPAPDY 861
Query: 239 -TQSGQPVDATADRHVVLSIPNGDFRPVCYEEPQHWCSVAYYEL 281
T PVD L+ P+ P E P + +A EL
Sbjct: 862 PTPCQYPVDGAQQSD--LTGPDCPRSPGLQEAPSSYDPLALSEL 903
>gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]
Length = 1083
Score = 37.7 bits (86), Expect = 0.022
Identities = 27/104 (25%), Positives = 36/104 (34%), Gaps = 3/104 (2%)
Query: 127 NPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPC 186
+P Y P P P + NPQ + A +++ P+ A P QP
Sbjct: 843 SPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQPSP 902
Query: 187 SALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLP 230
S P H + SP HSP S SP + P P
Sbjct: 903 S---PQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSP 943
Score = 30.0 bits (66), Expect = 4.7
Identities = 13/41 (31%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
Query: 192 SPSHAFSQSPCTASY--PHSPGSPSEPESPYQHSVDTPPLP 230
+P H S++P + P++P +PS E Y+++ D P P
Sbjct: 802 TPLHDGSRTPAQSGAWDPNNPNTPSRAEEEYEYAFDDEPTP 842
>gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]
Length = 1087
Score = 37.7 bits (86), Expect = 0.022
Identities = 27/104 (25%), Positives = 36/104 (34%), Gaps = 3/104 (2%)
Query: 127 NPYHYRRVETPVLPPVLVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSFQQPPC 186
+P Y P P P + NPQ + A +++ P+ A P QP
Sbjct: 847 SPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQPSP 906
Query: 187 SALPPSPSHAFSQSPCTASYPHSPGSPSEPESPYQHSVDTPPLP 230
S P H + SP HSP S SP + P P
Sbjct: 907 S---PQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSP 947
Score = 30.0 bits (66), Expect = 4.7
Identities = 13/41 (31%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
Query: 192 SPSHAFSQSPCTASY--PHSPGSPSEPESPYQHSVDTPPLP 230
+P H S++P + P++P +PS E Y+++ D P P
Sbjct: 806 TPLHDGSRTPAQSGAWDPNNPNTPSRAEEEYEYAFDDEPTP 846
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,529,703
Number of Sequences: 37866
Number of extensions: 1128768
Number of successful extensions: 6295
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 66
Number of HSP's successfully gapped in prelim test: 252
Number of HSP's that attempted gapping in prelim test: 5633
Number of HSP's gapped (non-prelim): 770
length of query: 467
length of database: 18,247,518
effective HSP length: 106
effective length of query: 361
effective length of database: 14,233,722
effective search space: 5138373642
effective search space used: 5138373642
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.