Guide to the Human Genome
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Name: SIK2 Sequence: fasta or formatted (926aa) NCBI GI: 38569460
Description:

SNF1-like kinase 2

Referenced in:

Additional Serine / Threonine Protein Kinases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.5         60           2
 C cysteine            1.6         15           1
 D aspartate           4.1         38           1
 E glutamate           7.0         65           3
 F phenylalanine       3.5         32           2
 G glycine             4.8         44           1
 H histidine           2.3         21           1
 I isoleucine          3.7         34           2
 K lysine              3.7         34           1
 L leucine            11.0        102           3
 M methionine          2.9         27           2
 N asparagine          3.5         32           2
 P proline            10.0         93          10
 Q glutamine           9.3         86           4
 R arginine            5.5         51           2
 S serine              8.2         76           2
 T threonine           3.7         34           1
 V valine              5.5         51           2
 W tryptophan          0.4          4           1
 Y tyrosine            2.9         27           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   SNF1-like kinase 2 
SIK1                  0.305   SNF1-like kinase 
QSK                   0.237   serine/threonine-protein kinase QSK 
MARK2                 0.180   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.180   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.180   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.180   MAP/microtubule affinity-regulating kinase 2 isofor...
MARK2                 0.180   MAP/microtubule affinity-regulating kinase 2 isoform...
MARK3                 0.179   MAP/microtubule affinity-regulating kinase 3 isofor...
MARK3                 0.179   MAP/microtubule affinity-regulating kinase 3 isofor...
MARK3                 0.179   MAP/microtubule affinity-regulating kinase 3 isofor...
MARK3                 0.179   MAP/microtubule affinity-regulating kinase 3 isoform...
MARK4                 0.178   MAP/microtubule affinity-regulating kinase 4 
MARK1                 0.177   MAP/microtubule affinity-regulating kinase 1 
BRSK2                 0.144   BR serine/threonine kinase 2 
PRKAA1                0.144   protein kinase, AMP-activated, alpha 1 catalytic sub...
PRKAA2                0.144   AMP-activated protein kinase alpha 2 catalytic subun...
BRSK1                 0.143   BR serine/threonine kinase 1 
PRKAA1                0.138   protein kinase, AMP-activated, alpha 1 catalytic sub...
SNRK                  0.135   SNF related kinase 
SNRK                  0.135   SNF related kinase 
MGC42105              0.130   serine/threonine-protein kinase NIM1 
NUAK1                 0.116   AMPK-related protein kinase 5 
NUAK2                 0.113   NUAK family, SNF1-like kinase, 2 
MELK                  0.109   maternal embryonic leucine zipper kinase 
TSSK1B                0.093   testis-specific serine kinase 1 
HUNK                  0.093   hormonally upregulated Neu-associated kinase 
TSSK2                 0.087   testis-specific serine kinase 2 
TSSK3                 0.086   testis-specific serine kinase 3 
DCLK3                 0.085   doublecortin-like kinase 3 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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