Guide to the Human Genome
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Search of human proteins with 112821690

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|112821690 G protein-regulated inducer of neurite outgrowth 3
[Homo sapiens]
         (776 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|112821690 G protein-regulated inducer of neurite outgrowth 3 ...  1536   0.0  
gi|112821681 G protein-regulated inducer of neurite outgrowth 1 ...   100   5e-21
gi|112821688 G protein-regulated inducer of neurite outgrowth 2 ...    74   4e-13
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        64   4e-10
gi|91982772 mucin 17 [Homo sapiens]                                    60   6e-09
gi|89026265 PREDICTED: mucin 12 [Homo sapiens]                         59   2e-08
gi|161016767 mucin 21 [Homo sapiens]                                   58   3e-08
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    55   2e-07
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   54   4e-07
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   54   4e-07
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   54   4e-07
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    54   4e-07
gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ...    54   7e-07
gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ...    54   7e-07
gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 ...    54   7e-07
gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ...    54   7e-07
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]       52   2e-06
gi|41281612 zinc finger protein 828 [Homo sapiens]                     52   3e-06
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                        51   5e-06
gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 ...    51   5e-06
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          50   8e-06
gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]             50   1e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni...    49   1e-05
gi|83367077 mucin 16 [Homo sapiens]                                    48   4e-05
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    48   4e-05
gi|27262645 ataxin 2 related protein isoform B [Homo sapiens]          48   4e-05
gi|27262649 ataxin 2 related protein isoform C [Homo sapiens]          48   4e-05
gi|27262647 ataxin 2 related protein isoform A [Homo sapiens]          48   4e-05
gi|27262651 ataxin 2 related protein isoform D [Homo sapiens]          48   4e-05
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        47   5e-05

>gi|112821690 G protein-regulated inducer of neurite outgrowth 3
           [Homo sapiens]
          Length = 776

 Score = 1536 bits (3978), Expect = 0.0
 Identities = 776/776 (100%), Positives = 776/776 (100%)

Query: 1   MGTVPDPLRSAKTSLIAASGKEDDLGEPQAASPRHRPALLCKNANGFSGAPAEPDLSPRA 60
           MGTVPDPLRSAKTSLIAASGKEDDLGEPQAASPRHRPALLCKNANGFSGAPAEPDLSPRA
Sbjct: 1   MGTVPDPLRSAKTSLIAASGKEDDLGEPQAASPRHRPALLCKNANGFSGAPAEPDLSPRA 60

Query: 61  AAEALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRD 120
           AAEALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRD
Sbjct: 61  AAEALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRD 120

Query: 121 LIHTPLTMPANQHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSS 180
           LIHTPLTMPANQHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSS
Sbjct: 121 LIHTPLTMPANQHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSS 180

Query: 181 SKDQVSCEFPSPETIQGTVQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTR 240
           SKDQVSCEFPSPETIQGTVQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTR
Sbjct: 181 SKDQVSCEFPSPETIQGTVQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTR 240

Query: 241 ESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEAST 300
           ESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEAST
Sbjct: 241 ESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEAST 300

Query: 301 MTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRV 360
           MTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRV
Sbjct: 301 MTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRV 360

Query: 361 ICHSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVLKT 420
           ICHSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVLKT
Sbjct: 361 ICHSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVLKT 420

Query: 421 SSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISACSQAE 480
           SSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISACSQAE
Sbjct: 421 SSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISACSQAE 480

Query: 481 TSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSGSLDPTNKGDAREKKP 540
           TSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSGSLDPTNKGDAREKKP
Sbjct: 481 TSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSGSLDPTNKGDAREKKP 540

Query: 541 ASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQESTLEENRQTK 600
           ASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQESTLEENRQTK
Sbjct: 541 ASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQESTLEENRQTK 600

Query: 601 TATSLSLPSDPMGDSSPGSGKKTPSRSVKASPRRPSRVSEFLKEQKLNVTAAAAQVGLTP 660
           TATSLSLPSDPMGDSSPGSGKKTPSRSVKASPRRPSRVSEFLKEQKLNVTAAAAQVGLTP
Sbjct: 601 TATSLSLPSDPMGDSSPGSGKKTPSRSVKASPRRPSRVSEFLKEQKLNVTAAAAQVGLTP 660

Query: 661 GDKKKQLGADSKLQLKQSKRVRDVVWDEQGMTWEVYGASLDAESLGIAIQNHLQRQIREH 720
           GDKKKQLGADSKLQLKQSKRVRDVVWDEQGMTWEVYGASLDAESLGIAIQNHLQRQIREH
Sbjct: 661 GDKKKQLGADSKLQLKQSKRVRDVVWDEQGMTWEVYGASLDAESLGIAIQNHLQRQIREH 720

Query: 721 EKLIKTQNSQTRRSISSDTSSNKKLRGRQHSVFQSMLQNFRRPNCCVRPAPSSVLD 776
           EKLIKTQNSQTRRSISSDTSSNKKLRGRQHSVFQSMLQNFRRPNCCVRPAPSSVLD
Sbjct: 721 EKLIKTQNSQTRRSISSDTSSNKKLRGRQHSVFQSMLQNFRRPNCCVRPAPSSVLD 776


>gi|112821681 G protein-regulated inducer of neurite outgrowth 1 [Homo
            sapiens]
          Length = 1008

 Score =  100 bits (249), Expect = 5e-21
 Identities = 112/425 (26%), Positives = 169/425 (39%), Gaps = 74/425 (17%)

Query: 409  KLASLPGGVLKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAK-KLAGTNSSSLKATA 467
            K  ++P G  K  S+ L   +   T K D R +G    +    A+ KL G   ++    A
Sbjct: 597  KAEAIPEG--KVGSLPLEKGSPVTTTKADPRASGKAQPQSGGKAETKLPGQEGAAAPGEA 654

Query: 468  ------------IDQISISACSQAET-------SYGLGKFETRPSEFAEKTTNGHKTDPD 508
                         +++   +C +AE           LGK ++ PS   E  + G      
Sbjct: 655  GAVCLKKETPQASEKVDPGSCRKAEPLASGKGEPVSLGKADSAPSRKTESPSLGKVVPLS 714

Query: 509  CKLSDSCGSISKADHSGSLDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLLLNPKS 568
             + +    S      S  LD    G AR  + A     +  E      S  +   L  K 
Sbjct: 715  LEKTKPSSS------SRQLDRKALGSARSPEGARGSEGRV-EPKAEPVSSTEASSLGQKD 767

Query: 569  QESGGTE-----SAANPTPSPIRKNQESTL-------------EENRQTKTATSLSLPSD 610
             E+ G E      AA P P P  ++  +               +   Q      +S+   
Sbjct: 768  LEAAGAERSPCPEAAAPPPGPRTRDNFTKAPSWEASAPPPPREDAGTQAGAQACVSVAVS 827

Query: 611  PMGDSSPGSGKKTPSRSVKASPRRPSRVSEFLKEQKLNVTAAAA------------QVGL 658
            PM   SP  G    + S +A+PR PS  S   ++  L V+  AA            Q   
Sbjct: 828  PM---SPQDGAGGSAFSFQAAPRAPSPPSR--RDAGLQVSLGAAETRSVATGPMTPQAAA 882

Query: 659  TPGDKKKQLGADSKLQL-----KQSKRVRDVVWDEQGMTWEVYGASLDAESLGIAIQNHL 713
             P   + ++   S L       + ++ VRDV WDE+GMTWEVYGA+++ E LG+AIQ HL
Sbjct: 883  PPAFPEVRVRPGSALAAAVAPPEPAEPVRDVSWDEKGMTWEVYGAAMEVEVLGMAIQKHL 942

Query: 714  QRQIREHEKL-----IKTQNSQTRRSISSDTSSNKKLRGRQHSVFQSMLQNFRRPNCCVR 768
            +RQI EH +           +   RS S  T+       R   +F+++LQ+ RRP CC R
Sbjct: 943  ERQIEEHGRQGAPAPPPAARAGPGRSGSVRTAPPDGAAKRPPGLFRALLQSVRRPRCCSR 1002

Query: 769  PAPSS 773
              P++
Sbjct: 1003 AGPTA 1007


>gi|112821688 G protein-regulated inducer of neurite outgrowth 2
           [Homo sapiens]
          Length = 458

 Score = 74.3 bits (181), Expect = 4e-13
 Identities = 82/271 (30%), Positives = 108/271 (39%), Gaps = 45/271 (16%)

Query: 526 SLDPTNKGDAREKKPASPQVVKEKESTGTDTSDA---KTLLLNPKSQESGGTESAANPT- 581
           S+ P + GD      ++    K  E   T T  A     LL   +   +GG   A   T 
Sbjct: 195 SVPPLDLGDTTAHSSSAQAEPKAAEQLATTTCHALPPAALLCGMREVRAGGCCHALPATG 254

Query: 582 ----PSPIRKNQESTLEENRQTKTATSLS--LPSD---------PMG-DSSPGSGKKTPS 625
               P  +    ES L+     K    LS  LP           P G    PGS  K   
Sbjct: 255 ILAFPKLVASVSESGLQAQHGVKIHCRLSGGLPGHSHCCAHLWGPAGLVPEPGSRTKDVW 314

Query: 626 RSVKASPRRPSRVSEFLKEQKLNV----TAAAAQVGLTPG-DKKKQLGADSKLQLKQSKR 680
               A+   P+  S  L  Q   V     AA   V  +P  +    L    ++ L  S  
Sbjct: 315 TMTSANDLAPAEASP-LSAQDAGVQAAPVAACKAVATSPSLEAPAALHVFPEVTLGSSLE 373

Query: 681 -----VRDVVWDEQGMTWEVYGASLDAESLGIAIQNHLQRQIREHEKLIKTQNSQTRRSI 735
                VRDV WD +GMTWEVYGA++D E LG+AIQ HL+ Q  + +          R   
Sbjct: 374 EVPSPVRDVRWDAEGMTWEVYGAAVDLEVLGVAIQKHLEMQFEQLQ----------RAPA 423

Query: 736 SSDTSSNKKLRGRQHSVFQSMLQNFRRPNCC 766
           S D+ S +  RG   +V QS+    RRP+CC
Sbjct: 424 SEDSLSVEGRRGPLRAVMQSL----RRPSCC 450



 Score = 31.2 bits (69), Expect = 3.8
 Identities = 18/47 (38%), Positives = 26/47 (55%)

Query: 293 SRFKEASTMTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSI 339
           SR K+  TMT+  +    E    + QDA VQA      ++V+TSPS+
Sbjct: 308 SRTKDVWTMTSANDLAPAEASPLSAQDAGVQAAPVAACKAVATSPSL 354


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 149/684 (21%), Positives = 240/684 (35%), Gaps = 85/684 (12%)

Query: 2    GTVPDPLRSAKTSLIA-------ASGKEDDLGEPQAASPRHRPALLCKNANGFSGAPAEP 54
            GT   P RSA + L+        +SG  +    P + +     A L + +  F  +P  P
Sbjct: 3203 GTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTT----AGLSEKSTTFYSSPRSP 3258

Query: 55   DLSPRAAAEALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPS 114
            D +   A+     V E  TT    S PG       +  T   PG+  +PG SQ + ++ S
Sbjct: 3259 DTTLSPASTTSSGVSEESTTSH--SRPG-------STHTTAFPGSTTMPGVSQESTASHS 3309

Query: 115  SAAGRDLIHTPLTMPAN-----QHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEK 169
            S    D   +P +  A+       T  S PG     +       S +    T        
Sbjct: 3310 SPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGS 3369

Query: 170  PSCPVGGVLSSSKDQVSCEFPS-PETIQGTVQTPVTAARVVSHSSSPVGGPEGERQGAIC 228
            P   +    S+++   S  F S P +   T   P T +  V  S++  G P         
Sbjct: 3370 PHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFS 3429

Query: 229  DSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPA 288
             S     +    E   + +  P  TA+ P    S T      ++   + P   + +  P 
Sbjct: 3430 ASSTTLGR---SEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPE 3486

Query: 289  QRQMS-RFKEASTMTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTS-----PSILTA 342
                S R +E++T  +     I   PS     A V+   S  S   ST+      S  T+
Sbjct: 3487 SDTTSGRGEESTTSHSSTTHTISSAPSTT--SALVEEPTSYHSSPGSTATTHFPDSSTTS 3544

Query: 343  FLKESRAPEHFEQEQLRVICHSSGSHT-LELSDSTLAP-----QESSQCPGI-------- 388
               E     H  Q+    I   + S T + L +ST +P      E++  PG         
Sbjct: 3545 GRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSE 3604

Query: 389  ----------MPQVHIQAAAAESTAFQRENKLA-SLPGGVLKTSSINLVS-------SNA 430
                       P   +  A+  S+    E+  + S PG    T+  +  +       S  
Sbjct: 3605 KSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTT 3664

Query: 431  QHTC--KEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISACS--QAETSYGLG 486
             H+     D  L   +     S+ +     +SS    TA+   S +A S  Q  T++   
Sbjct: 3665 SHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSS 3724

Query: 487  KFETRPSEFAEKTTNGHKTDPDCKLSDSCGS-ISKADHSGSLDPTNKGD--AREKKPASP 543
               T  + F + TT+    +   ++  S GS  +    + S  P  +G+  A +  PAS 
Sbjct: 3725 PGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPAST 3784

Query: 544  QVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQE-STLEENRQTKTA 602
                   ST T   +  T       +  G T +   P  S    + E ST+  +    + 
Sbjct: 3785 HTTPSPPSTATAPVEESTTY----HRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASG 3840

Query: 603  TSLSLPSDPMGDSSPGSGKKTPSR 626
            T+   PS     +S G G+ T SR
Sbjct: 3841 TT---PSSAHSTTS-GRGESTTSR 3860



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 145/687 (21%), Positives = 240/687 (34%), Gaps = 91/687 (13%)

Query: 2    GTVPDPLRSAKTSLIA-------ASGKEDDLGEPQAASPRHRPALLCKNANGFSGAPAEP 54
            GT   P RSA + L+        +SG  +    P + +     A L + +  F  +P  P
Sbjct: 1646 GTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTT----AGLSEKSTTFYSSPRSP 1701

Query: 55   DLSPRAAAEALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPS 114
            D +   A+     V E  TT    S PG       +  T   PG+  +PG SQ + ++ S
Sbjct: 1702 DTTLSPASTTSSGVSEESTTSH--SRPG-------STHTTAFPGSTTMPGVSQESTASHS 1752

Query: 115  SAAGRDLIHTPLTMPAN-----QHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEK 169
            S    D   +P +  A+       T  S PG     +       S +    T        
Sbjct: 1753 SPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGS 1812

Query: 170  PSCPVGGVLSSSKDQVSCEFPSPETIQGTVQT-PVTAARVVSHSSSPVGGPEGERQGAIC 228
            P   +    S+++   S  F S  + + T+   P T +  V  S++  G P         
Sbjct: 1813 PHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFS 1872

Query: 229  DSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPA 288
             S     +    E   + +  P  TA+ P    S T      ++   + P   + +  P 
Sbjct: 1873 ASSTTLGR---SEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPE 1929

Query: 289  QRQMS-RFKEASTMTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTS-----PSILTA 342
                S R +E+ T  +     I   PS     A V+   S  S   ST+      S  T+
Sbjct: 1930 SSTASGRSEESRTSHSSTTHTISSPPSTT--SALVEEPTSYHSSPGSTATTHFPDSSTTS 1987

Query: 343  FLKESRAPEHFEQEQLRVICHSSGSHT-LELSDSTLAP-----QESSQCPGI-------- 388
               E     H  Q+    I   + S T + L +ST +P      E++  PG         
Sbjct: 1988 GRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSE 2047

Query: 389  ----------MPQVHIQAAAAESTAFQRENKLA-SLPG--------------GVLKTSSI 423
                       P   +  A+  S+    E+  + S PG              G+ + S+ 
Sbjct: 2048 KSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTT 2107

Query: 424  NLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISACSQAETSY 483
            +  S  +  T           P +E +T+    G+  ++L   +   +S     Q  T++
Sbjct: 2108 SHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSF---GQESTTF 2164

Query: 484  GLGKFETRPSEFAEKTTNGHKTDPDCKLSDSCGS-ISKADHSGSLDPTNKGD--AREKKP 540
                  T  + F + TT+    +   ++  S GS  +    + S  P  +G+  A +  P
Sbjct: 2165 HSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHP 2224

Query: 541  ASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQE-STLEENRQT 599
            AS        ST T   +  T       +  G T +   P  S    + E ST+  +   
Sbjct: 2225 ASTHTTPSPPSTATAPVEESTTY----HRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPD 2280

Query: 600  KTATSLSLPSDPMGDSSPGSGKKTPSR 626
             + T+   PS     +S G G+ T SR
Sbjct: 2281 ASGTT---PSSAHSTTS-GRGESTTSR 2303



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 129/623 (20%), Positives = 219/623 (35%), Gaps = 119/623 (19%)

Query: 97   PGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMPAN-----QHTCQSIPGDQPNAITSSMP 151
            PG+   PG S+ + +  SS    D  H P +M ++       T  S PG   +  T++ P
Sbjct: 624  PGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPG---STHTTAFP 680

Query: 152  EDSLM-----RSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEFPS-PETIQGTVQTPVTA 205
              + M      S  + +   P   +   G   +SS       F S P + + T+    T 
Sbjct: 681  GSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTT 740

Query: 206  ARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTP 265
            A  +  +S PV             S  RS       +G +  +  S T      +    P
Sbjct: 741  ASGLLEASMPV------------HSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRP 788

Query: 266  QPTPLTS---EPSACPPG-PEKVP---LPAQRQMSRFKEASTMTNQAESEIK-----EVP 313
             P   TS   EPS    G P  +P   + A+   S   E ST  + +    +     E  
Sbjct: 789  APPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESD 848

Query: 314  SRAWQDAEVQAVASVESRSVSTSPSILTAFLKE---------SRAPEHFE-------QEQ 357
            + + +  E     S  + ++S++PS  +A ++E         S A  HF        + +
Sbjct: 849  TTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSE 908

Query: 358  LRVICHSSGSHT------------LELSDSTLAP-----QESSQCPGI------------ 388
                 HSS   T            + L +ST +P      E++  PG             
Sbjct: 909  ESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTT 968

Query: 389  ------MPQVHIQAAAAESTAFQRENKLA-SLPG--------------GVLKTSSINLVS 427
                   P   +  A+  S+    E+  + S PG              G+ + S+ +  S
Sbjct: 969  FHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSS 1028

Query: 428  SNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISACSQAETSYGLGK 487
              +  T           P +E +T+   +G+  ++L   +   +S     Q  T++    
Sbjct: 1029 PGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSF---GQESTTFHSNP 1085

Query: 488  FETRPSEFAEKTTNGHKTDPDCKLSDSCGS-ISKADHSGSLDPTNKGD--AREKKPASPQ 544
              T  + F + TT+    +   ++  S GS  +    + S  P  +G+  A +  PAS  
Sbjct: 1086 GSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTH 1145

Query: 545  VVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQE-STLEENRQTKTAT 603
                  ST T   +  T       +  G T +   P  S    + E ST+  +    + T
Sbjct: 1146 TTPSPPSTATAPVEESTTY----HRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGT 1201

Query: 604  SLSLPSDPMGDSSPGSGKKTPSR 626
            +   PS     +S G G+ T SR
Sbjct: 1202 T---PSSAHSTTS-GRGESTTSR 1220



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 146/714 (20%), Positives = 234/714 (32%), Gaps = 137/714 (19%)

Query: 2    GTVPDPLRSAKTSLIA-------ASGKEDDLGEPQAASPRHRPALLCKNANGFSGAPAEP 54
            GT   P RSA + L+        +SG  +    P + +     A L + +  F  +P  P
Sbjct: 4286 GTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTT----AGLSEKSTTFYSSPRSP 4341

Query: 55   DLSPRAAAEALMQVCEHETTQPDMSSPGVFNEV------------QKAPATFNSPGNPQL 102
            D +   A+     V E  TT    S PG  +              Q++ A+ +SPG+   
Sbjct: 4342 DTTLSPASTTSSGVSEESTTSH--SRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDT 4399

Query: 103  ---PGSSQPAASAPSS--------------------AAGRDLIHTPL-TMPANQHTCQSI 138
               PGS+  ++  P S                    A+G     TP+ +   + HT  S 
Sbjct: 4400 TLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLS- 4458

Query: 139  PGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVS------CEFPSP 192
                P   T+   E +  +S   S    P  P+     V  S+    S        F + 
Sbjct: 4459 ----PAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSAS 4514

Query: 193  ETIQGTVQ-------TPVTAARVVSHSSSPVGG----------PEGERQGAICDSEMRSC 235
             T  G  +       +PV  A   S + S   G            G  Q  +   E  + 
Sbjct: 4515 STTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQ-TMHFPESNTT 4573

Query: 236  KPLTRESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRF 295
                 ES  S +      +S P  T+++  +PT   S P +          P     S  
Sbjct: 4574 SGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGS----TATTHFPDSSTTSGR 4629

Query: 296  KEASTMTNQAESEIKEV--PSRAWQ-----DAEVQAVASVESRSVSTSPSILTAFLKESR 348
             E ST ++ ++     +  P+R+       ++    ++S    + +   S  T  L E  
Sbjct: 4630 SEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKS 4689

Query: 349  APEHFEQEQLRVICHSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQREN 408
               H           S+ S TL  S+ +     S       P     A +  S   +   
Sbjct: 4690 TTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPS---PARSTTSGLVEEST 4746

Query: 409  KLASLPGGVLKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAI 468
               S PG    T +++   S+      E+ R                  ++SS+    + 
Sbjct: 4747 AYHSSPG---STQTMHFPESSTASGRSEESRT-----------------SHSSTTHTISS 4786

Query: 469  DQISISACSQAETSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSGSLD 528
               + SA  +  TSY         + F E +T   +++      +S  S S  D +G + 
Sbjct: 4787 PPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSE------ESTASHSSPDTNG-IT 4839

Query: 529  P-----TNKGDAREK-----KPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAA 578
            P     T  G   E       P S +      +T T    AK+ +L   S+    T S A
Sbjct: 4840 PLPAHFTTSGRIAESTTFYISPGSMETTLASTAT-TPGLSAKSTILYSSSRSPDQTLSPA 4898

Query: 579  NPT-------PSPIRKNQESTLEENRQTKTATSLSLPSDPMGDSSPGSGKKTPS 625
            + T       P+ +    EST        T TS          S PGS + T S
Sbjct: 4899 SMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLS 4952



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 134/649 (20%), Positives = 213/649 (32%), Gaps = 76/649 (11%)

Query: 3    TVPDPLRSAKTSLIAASGKEDDLGEPQAASPRHRPALLCKNANGFSGAPAEPDLSPRAAA 62
            T P P RS  + L+  S        P +    H P      ++  SG   E   S  +  
Sbjct: 3453 TTPSPARSTTSGLVEESTTYHS--SPGSTQTMHFP-----ESDTTSGRGEESTTSHSSTT 3505

Query: 63   EALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLI 122
              +       TT   +  P  ++    + AT + P +    G S+ + ++ SS   +D  
Sbjct: 3506 HTISSA--PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSS---QDAT 3560

Query: 123  HTPLTMPANQHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSK 182
             T + +PA   T   +     + I+S   E + +    T+               LS   
Sbjct: 3561 GT-IVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPG-------------LSEKS 3606

Query: 183  DQVSCEFPSPETIQGTVQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRES 242
                    SP T      T  T++ V   S++    P      A  DS        T   
Sbjct: 3607 TTFHSSPRSPATTLSPAST--TSSGVSEESTTSHSRPGSTHTTAFPDS--------TTTP 3656

Query: 243  GCSENKQPSVTASGPQGTT----SVTPQPTPLTSEPSACPPGPEKVPL-PAQRQMSRFKE 297
            G S +   S ++ G   TT    S T   +   S  S    G     L P       F +
Sbjct: 3657 GLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQ 3716

Query: 298  ASTMTNQAESEIKEV--PSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQ 355
             ST  + +         P        V+A   V S + S   ++  A    S      + 
Sbjct: 3717 ESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPA----SSTSPGLQG 3772

Query: 356  EQLRVICHSSGSHTLELSDSTL-APQESS----QCPGIMPQVHIQAAAAESTAFQRENKL 410
            E      H + +HT     ST  AP E S    + PG  P  H  A++  S   ++    
Sbjct: 3773 ESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIF 3832

Query: 411  ASLP--GGVLKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAI 468
             S P   G   +S+ +  S   + T        G T +     +    G + +S    + 
Sbjct: 3833 HSSPDASGTTPSSAHSTTSGRGESTTSRIS--PGSTEITTLPGSTTTPGLSEASTTFYSS 3890

Query: 469  DQISISACSQAE-TSYGLGKFETRPSEFAEKTTNGHKT-DPDCKLSDSCGSISKADHSGS 526
             +   +  S A  TS G+G+  T        T   H T  P    +      S   +S S
Sbjct: 3891 PRSPTTTLSPASMTSLGVGEESTTSRSQPGST---HSTVSPASTTTPGLSEESTTVYSSS 3947

Query: 527  LDPTNKGDAREKKPASPQVVKEKEST-GTDTSDAKTLLLNPKSQESGGTESAANPTPSPI 585
              P +       +  +  V +E+ +T  +  +   T L    S  SG TE +     SP 
Sbjct: 3948 --PGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPA 4005

Query: 586  RKNQESTLEENRQTKTATSLSLPSDPMGDSSPGSGKKTPSRSVKASPRR 634
                         T+T    +L +  +G+ S      + S   K SP R
Sbjct: 4006 ------------STQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPAR 4042


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 155/731 (21%), Positives = 247/731 (33%), Gaps = 114/731 (15%)

Query: 28   PQAASPRHRPALLCKNANGFSGAPAEPDLSPRAAAEALMQVCEHETTQPDMSSPGVFNEV 87
            P A+ P     ++   AN  S  P +       + EA       E T    S+PG  +  
Sbjct: 1161 PLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTP 1220

Query: 88   -------------QKAPATFNSPGNPQLP-GSSQPAASAPSSAAGRDL------------ 121
                          +A     SP +   P  +S   +S+P++A G  L            
Sbjct: 1221 LTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLL 1280

Query: 122  ----IHTPLTMPANQHTCQSIPGDQPNAIT-----SSMPEDSLMRSQRTSNREQPEKP-- 170
                + T L       T  + P D    +      SS P  +   S  TS   +   P  
Sbjct: 1281 TSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLT 1340

Query: 171  SCPVGGVL-SSSKDQVSCEFPSPETIQGTVQTPVTAARVVSHSSSPVGGPEGERQGAICD 229
            S PV   L +SS   +    P   +   T  T   ++   S  +S       E    +  
Sbjct: 1341 SIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTS 1400

Query: 230  SEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACP---PGPEKVPL 286
              + S  P+      + +  P  T++   GTTS     +P T+E  + P   P   K PL
Sbjct: 1401 IPV-STTPVVSSEASTLSATPVDTST--PGTTSAEATSSPTTAEGISIPTSTPSEGKTPL 1457

Query: 287  ---PAQRQMSRFKEASTM-TNQAESEIKEVPSRAWQDAEVQA------------------ 324
               P         EAST+ T   +S    V S A   +   A                  
Sbjct: 1458 KSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALT 1517

Query: 325  --------VASVESRSVSTSPSI----LTAFLKESRAPEHFEQEQLRVICHSSGSHTL-E 371
                    VAS E  S+ST+P++    +T + + S +P   +   ++   +S GS  L  
Sbjct: 1518 SIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTS 1577

Query: 372  LSDSTLAPQES-----SQCP-GIMPQVHIQAAAAESTAFQRENKLASLP--GGVLKTSSI 423
            L  ST+    S     S  P     QV     A+ ST  +  +   S P  G  L TS  
Sbjct: 1578 LPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTS-- 1635

Query: 424  NLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISACSQAETSY 483
              +  +       +      TPV  +S +  +  T  SS   T  +  S+   +  E   
Sbjct: 1636 --IPVSTTPVASPEASTLSTTPV--DSNSPVITSTEVSS-SPTPAEGTSMPTSTYTEGRT 1690

Query: 484  GLGKFETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSGSLDPTNKGDAREKKPASP 543
             L     R +  A    +   T P    +    S        + + T+  ++   +  +P
Sbjct: 1691 PLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTP 1750

Query: 544  QVVKEKESTGTDTSDAKTLLLNP---KSQESGGTESAANPTPSPIRKNQESTLEENRQTK 600
                   +T   +S+A TL   P    +  +  TE+ ++PT +       STL E     
Sbjct: 1751 LTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPL 1810

Query: 601  TATSLS-----------LPSDPMGDSSP------GSGKKTPSRSVKASPRRPSRVSEFLK 643
            T+T +S           L + P+  +SP       S   TP+     +   PS  S  L 
Sbjct: 1811 TSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALT 1870

Query: 644  EQKLNVTAAAA 654
               ++ T  A+
Sbjct: 1871 SIPVSTTTVAS 1881



 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 129/587 (21%), Positives = 211/587 (35%), Gaps = 58/587 (9%)

Query: 73   TTQPDMSSPGVFN-EVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMPAN 131
            TT  D S+P   + E   +P T  S G   +P S+    S P +      + T L + + 
Sbjct: 3127 TTPVDTSTPVTTSTEAHSSPTT--SEGT-SMPTSTPSEGSTPLTYMP---VSTMLVVSSE 3180

Query: 132  QHTCQSIPGDQPNAITSSMPEDSLMRSQRTS-NREQPEKPSCPVGGVLSSSKDQVSCEFP 190
              T  + P D    +T+S    S   ++ TS     P +   P+  V  S+    S E  
Sbjct: 3181 DSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEAS 3240

Query: 191  SPETIQGTVQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQP 250
               T      TP+T +     SSSP   P  E       +      PLT     S     
Sbjct: 3241 ILSTTPVDSNTPLTTS--TEASSSP---PTAEGTSMPTSTPSEGSTPLT-----SMPVST 3290

Query: 251  SVTASGPQGTTSVTPQPT--PLT--SEPSACPPGPEKVPLPAQRQMSRFKEAST-MTNQA 305
            +  AS    T S TP  T  P+T  S+ S+ PP  +   +P     S + E ST +TN +
Sbjct: 3291 TTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPT----STYSEGSTPLTNMS 3346

Query: 306  ESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRVICHSS 365
             S    V S A         +++ +  V TS  + T+  + S +P   E   +     S 
Sbjct: 3347 FSTTPVVSSEA---------STLSTTPVDTSTPVTTS-TEASLSPTTAEGTSIPTSSPSE 3396

Query: 366  GSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVLKTSS--- 422
            G+  L     +  P  SS+    +    + +    +T+ +  +      G  L TS+   
Sbjct: 3397 GTTPLASMPVSTTPVVSSEV-NTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSE 3455

Query: 423  ----INLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISACSQ 478
                ++++  +       +      TPV   +     + TNSS    T  +  S+   + 
Sbjct: 3456 GSTPLSIMPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSP---TTAEVTSMPTSTA 3512

Query: 479  AETSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSGSLDPTNKGDAREK 538
             E S  L       +  A    +   T P    +    S   +    +L  T    +   
Sbjct: 3513 GEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPS 3572

Query: 539  KPASPQVVKEKESTGTDTSDAKTLL---LNPKSQESGGTESAANPTPSPIRKNQESTLEE 595
            + +S        ST   +S+A T     ++  +  +  T+S + PTP  +     ST  E
Sbjct: 3573 EGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSE 3632

Query: 596  NRQTKTATSLSLPSDPMGDSSPGS----GKKTP---SRSVKASPRRP 635
                 T   +S  S  + ++   S       TP   S  V +SP  P
Sbjct: 3633 VSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTP 3679



 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 115/563 (20%), Positives = 196/563 (34%), Gaps = 60/563 (10%)

Query: 91   PATFNSPGNPQLPGSSQP----AASAPSSAAGRDLIHTPLT-MPANQHTCQSIPGDQPNA 145
            P   N+P       SS P      S P+S +     +TPLT MP +     S       +
Sbjct: 2303 PVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEG--NTPLTRMPVSTTMVASFE----TS 2356

Query: 146  ITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGTVQTPVTA 205
              S+ P D+      T      +  S P     +S       E  +P T       PV +
Sbjct: 2357 TLSTTPADT-----STPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVS 2411

Query: 206  ARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTP 265
            +   +HS++PV     +    +  S   S  P T E        PS      +GTT +  
Sbjct: 2412 SEASTHSTTPV-----DTSTPVTTSTEASSSPTTAEGTSIPTSPPS------EGTTPLAS 2460

Query: 266  QPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEASTMTNQAESEIKEVPSRAWQD------ 319
             P   T   S+        P+     M+   EAS+    AE  +  + + +         
Sbjct: 2461 MPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSI 2520

Query: 320  -AEVQAVASVESRSVSTSP----SILTAFLKESRAPEHFEQEQLRVICHSSGS---HTLE 371
                  VAS E+ ++ST+P    S +    + S +    E   +    +S GS    ++ 
Sbjct: 2521 PVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMP 2580

Query: 372  LSDSTLAPQESSQCPGIMPQVHIQ-AAAAESTAFQRENKLASLPGGVLKTSSINLVS--S 428
            +S   LA  E+S          I    + E+++     K  S+P       S +L S   
Sbjct: 2581 VSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILV 2640

Query: 429  NAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISACSQAETSYGLGKF 488
            +       +      TPV   +      GT+SS    T  +  S+   +  E S  L   
Sbjct: 2641 STMPVASSEASTLSTTPVDTRTLVTTSTGTSSS---PTTAEGSSMPTSTPGERSTPLTNI 2697

Query: 489  ETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSGSLDPTNKGDARE-------KKPA 541
                +  A    +   T P     D+   ++ +  + S   T +G +           P 
Sbjct: 2698 LVSTTLLANSEASTLSTTP----VDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPL 2753

Query: 542  SPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQESTLEENRQTKT 601
            +  +V       ++ S   T  ++     +  TE++++PT + +     ST  E   +  
Sbjct: 2754 TSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSET--STP 2811

Query: 602  ATSLSLPSDPMGDSSPGSGKKTP 624
             TS+ +   P+  S  G+   TP
Sbjct: 2812 LTSMPVNHTPVASSEAGTLSTTP 2834



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 128/587 (21%), Positives = 202/587 (34%), Gaps = 89/587 (15%)

Query: 73   TTQPDMSSPGVFNEVQKAPATFNSPGNPQL---PGSSQPAASAPSSAAGRDLIHTPLTMP 129
            TT  + SS     E    P +  S G+  L   P S+ P AS  +S     L  TP+   
Sbjct: 2488 TTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEAST----LSTTPVDSN 2543

Query: 130  ANQHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEF 189
            +   T   I     +A  +SMP  +                S P+  +  S+K   S E 
Sbjct: 2544 SPVVTSTEISSSATSAEGTSMPTSTYSEG------------STPLRSMPVSTKPLASSEA 2591

Query: 190  PSPETIQGTVQTPVTAARVVSHS-------SSPVGGPEGERQGAICDSEMRSCKPLTRES 242
             +  T       PVT +   S S       S P+  P          S + S  P+    
Sbjct: 2592 STLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPS--EVSTSLTSILVSTMPVASSE 2649

Query: 243  GCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACP---PGPEKVPLPAQRQMSRFKEAS 299
              + +  P  T +    TTS     +P T+E S+ P   PG    PL      +     +
Sbjct: 2650 ASTLSTTPVDTRT--LVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLT-----NILVSTT 2702

Query: 300  TMTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLR 359
             + N   S +   P                   V TS  + T+  + S +P   E   +R
Sbjct: 2703 LLANSEASTLSTTP-------------------VDTSTPVTTS-AEASSSPTTAEGTSMR 2742

Query: 360  VICHSSGSHTLE---LSDSTLAPQESSQCPGIMPQVHIQAAAA-ESTAFQRENKLASLPG 415
            +   S GS  L    +S   +A  E+S          I    + E+++     ++ S+P 
Sbjct: 2743 ISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPT 2802

Query: 416  GVLKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAID-QISIS 474
                 +S  L S    HT         ++    +++      T +SS   TA    + IS
Sbjct: 2803 STPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPIS 2862

Query: 475  ACSQAETSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSGSLDPTNKGD 534
              S+  T        T P   +E +T                S +  D S  +  + +G 
Sbjct: 2863 TASEGSTLLTSIPVSTTPVASSEASTL---------------STTPVDTSIPVTTSTEGS 2907

Query: 535  AREKKPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQESTLE 594
            +    P + +      ST ++ S   T +L      +G   S  + TP   R    ++ E
Sbjct: 2908 S---SPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAE 2964

Query: 595  ENRQTKTATSLSLPSDPMGDSSPGSGKKTP--SRSVKASPRRPSRVS 639
             +    TA   S+P      S+PG  ++TP  S SV   P   S  S
Sbjct: 2965 ASSSPTTAEGTSMPI-----STPGE-RRTPLTSMSVSTMPVASSEAS 3005



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 133/589 (22%), Positives = 200/589 (33%), Gaps = 87/589 (14%)

Query: 91  PATFNSPGNPQLPGSSQPAA----SAPSSA---AGRDLIHTPL-TMP---ANQHTCQSIP 139
           PA  N P       SS P      S P+S        L  TP  TMP   +   T    P
Sbjct: 299 PAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITP 358

Query: 140 GDQPNAIT-----SSMPEDSLMRSQRTSNREQPEKP--SCPVGGVLSSSKDQVSCEFPSP 192
            D    +T     SS+P  +   S  TS   +   P  + PV  +L +S      E  + 
Sbjct: 359 VDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASS-----EASTT 413

Query: 193 ETIQGTVQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTR--------ESGC 244
            TI    +T VT A   S  SSP      E       +      PLT          S  
Sbjct: 414 STIPVDSKTFVTTASEAS--SSPT---TAEDTSIATSTPSEGSTPLTSMPVSTTPVASSE 468

Query: 245 SENKQPSVTASGPQGTTSVTPQPTPLTSEPSACP---PGPEKVPLPAQRQMSRFKEASTM 301
           + N   +   S  Q TTS     +P T+E ++ P   P     PL +          S  
Sbjct: 469 ASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSM---------SVS 519

Query: 302 TNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSP---SILTAFLKESRAPEHFEQEQL 358
           T    S      S    D       S E+ S ST+P   SI T+   E   P        
Sbjct: 520 TMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVST 579

Query: 359 RVICHSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVL 418
           R++  S      E S ++  P +S+       +    +  AE T         S+P    
Sbjct: 580 RLVVSS------EASTTSTTPADSNTFVTTSSEASSSSTTAEGT---------SMPTSTY 624

Query: 419 KTSSINLVSSNAQHT--CKEDGRLAGMTPVREES--TAKKLAGTNSSSLKATAIDQISIS 474
                 + S +   T     +      TPV   +  T    A ++S++ + T++   + +
Sbjct: 625 SERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYT 684

Query: 475 ACSQAETSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSGSLDPTNKGD 534
             S   TS  +       SE +  +T    T      S    S S     G+  PT+   
Sbjct: 685 EGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASS-SPTTADGASMPTST-P 742

Query: 535 AREKKPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQESTLE 594
           +    P +   V +   T ++ S   T  L+  +  +  TE++ +PT +       ST  
Sbjct: 743 SEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPS 802

Query: 595 ENRQTKTATSLS-----------LPSDPMGDSSPGSGKKTPSRSVKASP 632
           E     T+  +S           L + P+  +SP     T S  V +SP
Sbjct: 803 EGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSP----VTTSTEVSSSP 847



 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 116/590 (19%), Positives = 200/590 (33%), Gaps = 47/590 (7%)

Query: 49   GAPAEPDLSPRAAAEALMQVCEHETTQPDMSSP-GVFNEVQKAPATFNSPGNPQLPGSSQ 107
            G P    +       A  ++    TT  D  +P   +++   +P T +    P       
Sbjct: 1924 GRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPT------ 1977

Query: 108  PAASAPSSAAGRDLIHTPLTMPANQHTCQSIPGDQPNAIT-----SSMPEDSLMRSQRTS 162
            PA S  S+      + T L + +   T  + P D     T     SS P  +   S +TS
Sbjct: 1978 PAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTS 2037

Query: 163  NREQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGTVQTPVTAARVVSHSSSPVGGPEGE 222
                P + + P+ G+  S+   VS E  +  T     +T VT +   S S++  G     
Sbjct: 2038 T---PSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGS---- 2090

Query: 223  RQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPE 282
               ++  S      PL      S     S  AS    T   +  P   ++E S+ P   E
Sbjct: 2091 ---SMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTE 2147

Query: 283  KVPLPAQRQMSRFKEASTM---TNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSI 339
               +       R    ++M   T    S      S    D       S E+RS   SP+ 
Sbjct: 2148 GTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARS---SPTT 2204

Query: 340  LTAFLKESRAPEHFEQEQLRVICHSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAA 399
                   +  P         +   +    T E S  +  P ++S       +       A
Sbjct: 2205 SEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTA 2264

Query: 400  ESTAFQRENKLASLPGGVLKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTN 459
            E T         S+P   L   +  L S    HT   +  ++ ++    +S       T 
Sbjct: 2265 EGT---------SIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTE 2315

Query: 460  SSSLKATAIDQISISACSQAETSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDSCGSIS 519
            +SS   TA +  S+   + +E +  L +     +  A   T+   T P    +D+   ++
Sbjct: 2316 ASSPPPTA-EGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTP----ADTSTPVT 2370

Query: 520  KADHSGS----LDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTE 575
                +GS     D T+   +   + ++P       +    +S+A T    P    +  T 
Sbjct: 2371 TYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTT 2430

Query: 576  SA-ANPTPSPIRKNQESTLEENRQTKTATSLSLPSDPMGDSSPGSGKKTP 624
            S  A+ +P+        T   +  T    S+ + + P+  S  G+   TP
Sbjct: 2431 STEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTP 2480



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 106/536 (19%), Positives = 194/536 (36%), Gaps = 67/536 (12%)

Query: 171 SCPVGGVLSSSKDQVSCEFPSPETIQGTVQTPVTAARVVSHSSSPVGG--PEGERQGAIC 228
           SC     ++S +  V+ + P    +  T  TP T +R  S S+S      P      +  
Sbjct: 84  SCSTNPEMTSIESSVTSDTPG---VSSTRMTP-TESRTTSESTSDSTTLFPSSTEDTSSP 139

Query: 229 DSEMRSCKPLTRESGCSENKQPSVTASGP----QGTTSVT---PQPTPLTS--EPSACPP 279
            +   +  P++  S  S +   +  ++ P    +  TS+T      TPLT+  + S+ P 
Sbjct: 140 TTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPT 199

Query: 280 GPEKVPLPAQRQMSRFKEASTMTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSI 339
            PE   +P            +  ++  + +  +P+   + A  +A+  + +    ++P  
Sbjct: 200 TPESTTIP-----------KSTNSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVT 248

Query: 340 LTAFLKESRAPEHFEQEQLRVICHSSGSHTLE---LSDSTLAPQESSQCPGIMPQVHIQA 396
           ++A  + S +P   E   L     S GS  L    LS   +   E+S         +I  
Sbjct: 249 ISA--QASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPV 306

Query: 397 -AAAESTAFQRENKLASLPGGVLKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKL 455
             + E+++     +  S+P       S  L S+ A         ++ ++    +++    
Sbjct: 307 ITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVT 366

Query: 456 AGTNSSSLKATAIDQISISACSQAETSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDSC 515
             T  SSL  TA +  S+   + +E S  L          A    +   T P     DS 
Sbjct: 367 TSTEPSSLPTTA-EATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIP----VDSK 421

Query: 516 GSISKADHSGSLDPTNKGD--------AREKKPASPQVVKEKESTGTDTSDAKTLLLNPK 567
             ++ A  + S  PT   D        +    P +   V       ++ S+  T  ++ K
Sbjct: 422 TFVTTASEASS-SPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSK 480

Query: 568 SQESGGTESAANPTPSPIRKNQESTLEENRQTKTATSLSL-----------------PSD 610
           +Q +  TE++++P  + +     ST  E     T+ S+S                   S 
Sbjct: 481 TQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTST 540

Query: 611 PMGDSSPGSGKKTPSRSVKASPRRPSRVSEFLKEQ----KLNVTAAAAQVGLTPGD 662
           P+  SS  S   T           PS  S  L       +L V++ A+    TP D
Sbjct: 541 PVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPAD 596



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 126/611 (20%), Positives = 215/611 (35%), Gaps = 76/611 (12%)

Query: 73   TTQPDMSSPGVF-NEVQKAPATFNSPGNPQLPGSS--QPAASAPSSAAGRDLIHTPLTMP 129
            TT  D   P V  NEV  +P        P    S    P  S P        ++T L   
Sbjct: 1300 TTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIP--------VNTTLVAS 1351

Query: 130  ANQHTCQSIPGDQPNAITSSM-----PEDSLMRSQRTSNREQPEKP--SCPVGG--VLSS 180
            +      + P D    +T+S      P  S   S   SN  +   P  S PV    V+SS
Sbjct: 1352 SAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSS 1411

Query: 181  SKDQVSCEFPSPETIQGTVQ-----TPVTAARVVSHSSSPVGGPE-------------GE 222
                +S   P   +  GT       +P TA  +   +S+P  G                 
Sbjct: 1412 EASTLSAT-PVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANS 1470

Query: 223  RQGAICDSEMRSCKPLTRESGCSENKQP----SVTASGP-QGTTSVTPQPTPLTSEPSAC 277
                +  + + S  P+   +  S +  P    S+  S P +G+T++T  P   T+  S+ 
Sbjct: 1471 EASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSE 1530

Query: 278  PPGPEKVPLPAQRQMSRFKEASTMTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSP 337
                   P      ++ + +AS+    A+    +  + +     + ++       VS+  
Sbjct: 1531 INSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEA 1590

Query: 338  SILTAFLKESRAPEHFEQEQLRVICHSSGSHTLELSDSTLA-PQESSQCPGIMPQVHIQA 396
            + L+    +S+        Q+     +S S T E S  T++ P E S     +P      
Sbjct: 1591 NTLSTTPIDSKT-------QVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPV 1643

Query: 397  AAAESTAFQRENKLASLPGGVLKTSSINLVSSNAQHTCKEDGRLA-GMTPVREEST-AKK 454
            A+ E++        ++ P  V+ ++ ++   + A+ T         G TP+   +     
Sbjct: 1644 ASPEASTLSTTPVDSNSP--VITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTP 1701

Query: 455  LAGTNSSSLKATAIDQ-----ISISACSQAETSYGLGKFETRPSEFAEKTTN-GHKTDPD 508
            +A +  S+L  T +D       S  A S   TS G     + PSE     T+    T P 
Sbjct: 1702 VASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPV 1761

Query: 509  CKLSDSCGSISKADHSG----SLDPTNKGDAREKKPASPQVVKEKESTGTDT-------- 556
                 S  S +  D S     S + T+     E        + E  +  T T        
Sbjct: 1762 LSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVA 1821

Query: 557  -SDAKTLLLNPKSQESGG-TESAANPTPSPIRKNQESTLEENRQTKTATSLSLPSDPMGD 614
             S+A TL   P    S   T +A + +P+P      +T   +  +   TS+ + +  +  
Sbjct: 1822 NSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVAS 1881

Query: 615  SSPGSGKKTPS 625
            S   +   TP+
Sbjct: 1882 SETNTLSTTPA 1892



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 124/634 (19%), Positives = 213/634 (33%), Gaps = 66/634 (10%)

Query: 78   MSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAA--SAPSSAAGRDLIHTPLTMPANQHTC 135
            +S+  V +      +T  S   P   G+S P +  S  S+   R  + T +   +   T 
Sbjct: 1003 LSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTL 1062

Query: 136  QSIPGDQPNAITS-SMPEDSLMRSQRTSNREQP-EKPSCPVGGVLSSSKDQVSCEFPSPE 193
             + P D    +T+ S    S   +  TS       + S P+  V  S++  VS E  +  
Sbjct: 1063 STTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLS 1122

Query: 194  TIQGTVQTPVTAARVVSHSSSPVGG------PEGERQGAICDSEMRSCKPLTRESGCSEN 247
            T       PVT +   S S +   G      P  E    +    + +   ++ E+     
Sbjct: 1123 TTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLST 1182

Query: 248  KQ--------PSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPL---PAQRQMSRFK 296
                       S  AS P  T  VT  PT          PG    PL   P +       
Sbjct: 1183 TPVDSKTQVATSTEASSPPPTAEVTSMPT--------STPGERSTPLTSMPVRHTPVASS 1234

Query: 297  EASTM-TNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQ 355
            EAST+ T+  ++      S     +   A  +    S ++  S L   +  S        
Sbjct: 1235 EASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTT------ 1288

Query: 356  EQLRVICHSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPG 415
                ++     S  L     T  P  +S      P      +   ST  +    L S+P 
Sbjct: 1289 ----LVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPV 1344

Query: 416  G--VLKTSSINLVSSNA--QHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQI 471
               ++ +S+I+++S+      T       A  +P   E T+   +  +  +   T+I   
Sbjct: 1345 NTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVS 1404

Query: 472  SISACSQAETSYGLGKFET-RPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSG---SL 527
            +    S   ++      +T  P   + + T+   T     +  S  S  K        S 
Sbjct: 1405 TTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSN 1464

Query: 528  DPTNKGDAREKKPA-----SPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTP 582
             P    +A           SP V     S+    ++  ++ ++  S+ S    +A    P
Sbjct: 1465 TPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGS----TALTSIP 1520

Query: 583  SPIRKNQESTLEENRQTKTATSLSLPSDPMGDSSP----GSGKKTPSRSVKASPRRPSRV 638
                    S +     T   TS  + +     SSP    G+  +T + S  ++P     V
Sbjct: 1521 VSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPV 1580

Query: 639  SEFLKEQKLNVTAAAAQVGLTPGDKKKQLGADSK 672
            S  L      V++ A  +  TP D K Q+ A ++
Sbjct: 1581 STMLV-----VSSEANTLSTTPIDSKTQVTASTE 1609



 Score = 37.7 bits (86), Expect = 0.041
 Identities = 74/291 (25%), Positives = 111/291 (38%), Gaps = 37/291 (12%)

Query: 73   TTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAA----SAPSSAAGRDLIHTPLT- 127
            +T P  SS    + +   P   ++P     P +S P      S P+S AG     TPLT 
Sbjct: 3466 STTPVASSEA--STLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEG--STPLTN 3521

Query: 128  MPANQ--------HTCQSIPGDQPNAITSSMPEDSLMRSQR--TSNREQPEKPSCPVGGV 177
            MP +          T  + P D    +TSS    S   + +  T     P + S  +  +
Sbjct: 3522 MPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTM 3581

Query: 178  LSSSKDQVSCEFPSPETIQGTVQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKP 237
            L SS    S E  +P T      TPVT +   + S+S    PE         SE+ +   
Sbjct: 3582 LLSSTYVTSSEASTPSTPSVDRSTPVTTS---TQSNSTPTPPEVITLPMSTPSEVSTPLT 3638

Query: 238  LTRESGCSENKQPSVTASG-PQGT-----TSVTPQPTPLTSEPSACP---PGPEKVPL-- 286
            +   S  S     + TAS  P  T     TS     +P+T E +  P   P     PL  
Sbjct: 3639 IMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTT 3698

Query: 287  -PAQRQMSRFKEASTMTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTS 336
             P         E ST++    S +   P     +A + + A+++S ++S S
Sbjct: 3699 MPVSTTRVTSSEGSTLS--TPSVVTSTPVTTSTEA-ISSSATLDSTTMSVS 3746



 Score = 30.4 bits (67), Expect = 6.5
 Identities = 27/120 (22%), Positives = 40/120 (33%), Gaps = 10/120 (8%)

Query: 191  SPETIQGTVQTPVTAAR-------VVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESG 243
            +P T       PVT +        + SH+  P   P          +   +  P    + 
Sbjct: 4033 TPHTSTSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTM 4092

Query: 244  CSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPL---PAQRQMSRFKEAST 300
             +  K  + T S P  TT+  P  T + S P++ P  P          Q   SR K   T
Sbjct: 4093 TTRTKPSTRTTSFPTVTTTAVPTNTTIKSNPTSTPTVPRTTTCFGDGCQNTASRCKNGGT 4152


>gi|89026265 PREDICTED: mucin 12 [Homo sapiens]
          Length = 978

 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 141/631 (22%), Positives = 209/631 (33%), Gaps = 97/631 (15%)

Query: 7   PLRSAKTSLIAASGKEDDLGEPQAASPRHRPALLCKNANGFSGAPAEPDLSPRAAAEALM 66
           P+ S  T   A  G     G             L + +  F  +P  PD +   A+    
Sbjct: 3   PISSGSTETTALPGSTTTAG-------------LSEKSTTFYSSPRSPDTTLSPASTTSS 49

Query: 67  QVCEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTPL 126
            V E  TT    S PG       +  T   PG+  +PG SQ + ++ SS    D   +P 
Sbjct: 50  GVSEESTTSH--SRPG-------STHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPG 100

Query: 127 TMPAN-----QHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSS 181
           +  A+       T  S PG     +       S +    T        P   +    S++
Sbjct: 101 STTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTT 160

Query: 182 KDQVSCEFPS-PETIQGTVQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTR 240
           +   S  F S P +   T   P T +  V  S++  G P              S  P T 
Sbjct: 161 RQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSP--------------SSTPTTH 206

Query: 241 ESGCSE---NKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKE 297
            S  S      + S T       T+ TP P   T+              P   Q   F E
Sbjct: 207 FSASSTTLGRSEESTTVHSSPVATATTPSPARSTTS-GLVEESTAYHSSPGSTQTMHFPE 265

Query: 298 ASTMTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQ 357
           +ST + ++E              E +   S  + ++S+ PS  +A ++E  +  H     
Sbjct: 266 SSTASGRSE--------------ESRTSHSSTTHTISSPPSTTSALVEEPTS-YHSSPGS 310

Query: 358 LRVICHSSGSHTLELSDSTLAPQESSQCPGIMP-QVHIQAAA--AESTAF-----QRENK 409
           +        S T   S+ + A   S    GI P   H   +   AEST F       E  
Sbjct: 311 IATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETT 370

Query: 410 LAS---LPGGVLKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKA- 465
           LAS    PG   K++ +   S +   T       +        S   +   T++++  A 
Sbjct: 371 LASTTTTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPAS 430

Query: 466 ---TAIDQISISACSQ---AETSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSD------ 513
              + + Q S +  S+    ET+   G   T  S FA++ T  H + P   LS       
Sbjct: 431 TTTSGLSQESTTFHSKPGSTETTLSPGSITT--SSFAQEFTTPH-SQPGSALSTVSPAST 487

Query: 514 -----SCGSISKADHSGSLDPTNKGDAREKKPASPQVVKEKESTG-TDTSDAKTLLLNPK 567
                S  S +     GS + T    +      S Q     +S G T T    TL     
Sbjct: 488 TVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDI 547

Query: 568 SQESGGTES---AANPTPSPIRKNQESTLEE 595
            QES    S   A   TP P R      + E
Sbjct: 548 GQESTAFHSSSDATGTTPLPARSTASDLVGE 578


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 83/339 (24%), Positives = 117/339 (34%), Gaps = 41/339 (12%)

Query: 298 ASTMTNQAESEIKEVPSRAWQD----AEVQAVASVESRSVSTSPSILTAFLKESRAPEHF 353
           AST TN   S      S A           A  +  S S +TS    TA   ES      
Sbjct: 117 ASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTT--- 173

Query: 354 EQEQLRVICHSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASL 413
                     SSG+ T   S+S+     +S             ++  STA   E++  S 
Sbjct: 174 ----------SSGASTATNSESSTVSSRASTATNSESST---TSSGASTATNSESRTTSN 220

Query: 414 PGGVLKTSSINLVSSNAQHTCKEDGRL----AGMTPVREESTAKKLAGTNSSSLKATAID 469
             G    S  +  SS A      +       AG     E ST    AGT ++S  +T   
Sbjct: 221 GAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSS 280

Query: 470 QISISACSQAETSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSGSLDP 529
            IS    S++ T          PS  A   TN   +      + +  S S    SG+   
Sbjct: 281 GISTVTNSESST----------PSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTA 330

Query: 530 TNKGDAREKKPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKN- 588
           TN   +     AS     E  +T   +S A T   +  S  S GT +A N   S +    
Sbjct: 331 TNSESSTTSSGASTATNSESSTT---SSGASTATNSGSSTTSSGTSTATNSESSTVSSGA 387

Query: 589 QESTLEENRQTKTATSLSLPSDPMGDSSPGSGKKTPSRS 627
             +T  E+  T +  S +  S+    S+  SG  T + S
Sbjct: 388 STATTSESSTTSSGASTATNSE---SSTVSSGASTATNS 423



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 110/482 (22%), Positives = 156/482 (32%), Gaps = 55/482 (11%)

Query: 171 SCPVGGVLSSSKDQVSCEFPSPETIQGTVQTPVTAARVVSHSSSPVGGPEGERQGAICDS 230
           S   G  + SS    +    S  T  G     ++ + V S+  S V   E     +   +
Sbjct: 30  SANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTSSGIST 89

Query: 231 EMRSCKPLTRESGCS--ENKQPSVTASGPQGTT---SVTPQP---TPLTSEPSACPPGPE 282
              S +  T  SG S   N + S T+SG    T   S TP     T   S+ S    G  
Sbjct: 90  ATNS-EFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGAS 148

Query: 283 KVPLPAQRQMSRFKEASTMTNQAESEIKEVPSRAWQD----AEVQAVASVESRSVSTSPS 338
                     S   EAST TN   S      S A          +A  +  S S +TS  
Sbjct: 149 TATNSDSSTTS--SEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSG 206

Query: 339 ILTAFLKESRAPEHFEQEQLRVICHSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAA 398
             TA   ESR   +           +S S T     ST    ESS             ++
Sbjct: 207 ASTATNSESRTTSNGAGTAT-----NSESSTTSSGASTATNSESST-----------PSS 250

Query: 399 AESTAFQRENKLASLPGGVLKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGT 458
              TA   E+   S   G    S  + VSS        +      TP    +TA     +
Sbjct: 251 GAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESS----TPSSGANTATNSESS 306

Query: 459 NSSSLKATAIDQISISACSQAETSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDSCGSI 518
            +SS   TA +  S +  S A T+                 TN   +      S +  S 
Sbjct: 307 TTSSGANTATNSDSSTTSSGASTA-----------------TNSESSTTSSGASTATNSE 349

Query: 519 SKADHSGSLDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAA 578
           S    SG+   TN G +      S     E   + T +S A T   +  S  S G  +A 
Sbjct: 350 SSTTSSGASTATNSGSSTTSSGTSTATNSE---SSTVSSGASTATTSESSTTSSGASTAT 406

Query: 579 NPTPSPIRKNQESTLEENRQTKTATSLSLPSDPMGDSSPGSGKKTPSRSVKASPRRPSRV 638
           N   S +     +       T ++ + +  +     +S GSG    +     S    + V
Sbjct: 407 NSESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAV 466

Query: 639 SE 640
           SE
Sbjct: 467 SE 468


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 95/422 (22%), Positives = 147/422 (34%), Gaps = 62/422 (14%)

Query: 2    GTVPDPLRSAKTSLIA-------ASGKEDDLGEPQAASPRHRPALLCKNANGFSGAPAEP 54
            GT   P RSA + L+        +SG  +    P + +     A L + +  F  +P  P
Sbjct: 1133 GTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTT----AGLSEKSTTFYSSPRSP 1188

Query: 55   DLSPRAAAEALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPS 114
            D +   A+     V E  TT    S PG       +  T   PG+  +PG SQ + ++ S
Sbjct: 1189 DTTLSPASTTSSGVSEESTTSH--SRPG-------STHTTAFPGSTTMPGVSQESTASHS 1239

Query: 115  SAAGRDLIHTPLTMPAN-----QHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEK 169
            S    D   +P +  A+       T  S PG     +       S +    T        
Sbjct: 1240 SPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGS 1299

Query: 170  PSCPVGGVLSSSKDQVSCEFPSPETIQGTVQT-PVTAARVVSHSSSPVGGPEGERQGAIC 228
            P   +    S+++   S  F S  + + T+   P T +  V  S++  G P         
Sbjct: 1300 PHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSP--------- 1350

Query: 229  DSEMRSCKPLTRESGCSE---NKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVP 285
                 S  P T  S  S      + S T       T+ TP P   T+             
Sbjct: 1351 -----SSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTS-GLVEESTAYHS 1404

Query: 286  LPAQRQMSRFKEASTMTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLK 345
             P   Q   F E+ST + ++E              E +   S  + ++S+ PS  +A ++
Sbjct: 1405 SPGSTQTMHFPESSTASGRSE--------------ESRTSHSSTTHTISSPPSTTSALVE 1450

Query: 346  ESRAPEHFEQEQLRVICHSSGSHTLELSDSTLAPQESSQCPGIMP-QVHIQAAA--AEST 402
            E  +  H     +        S T   S+ + A   S    GI P   H   +   AEST
Sbjct: 1451 EPTS-YHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAEST 1509

Query: 403  AF 404
             F
Sbjct: 1510 TF 1511



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 129/623 (20%), Positives = 219/623 (35%), Gaps = 119/623 (19%)

Query: 97  PGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMPAN-----QHTCQSIPGDQPNAITSSMP 151
           PG+   PG S+ + +  SS    D  H P +M ++       T  S PG   +  T++ P
Sbjct: 111 PGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPG---STHTTAFP 167

Query: 152 EDSLM-----RSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEFPS-PETIQGTVQTPVTA 205
             + M      S  + +   P   +   G   +SS       F S P + + T+    T 
Sbjct: 168 GSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTT 227

Query: 206 ARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTP 265
           A  +  +S PV             S  RS       +G +  +  S T      +    P
Sbjct: 228 ASGLLEASMPV------------HSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRP 275

Query: 266 QPTPLTS---EPSACPPG-PEKVP---LPAQRQMSRFKEASTMTNQAESEIK-----EVP 313
            P   TS   EPS    G P  +P   + A+   S   E ST  + +    +     E  
Sbjct: 276 APPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESD 335

Query: 314 SRAWQDAEVQAVASVESRSVSTSPSILTAFLKE---------SRAPEHFE-------QEQ 357
           + + +  E     S  + ++S++PS  +A ++E         S A  HF        + +
Sbjct: 336 TTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSE 395

Query: 358 LRVICHSSGSHT------------LELSDSTLAP-----QESSQCPGI------------ 388
                HSS   T            + L +ST +P      E++  PG             
Sbjct: 396 ESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTT 455

Query: 389 ------MPQVHIQAAAAESTAFQRENKLA-SLPG--------------GVLKTSSINLVS 427
                  P   +  A+  S+    E+  + S PG              G+ + S+ +  S
Sbjct: 456 FHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSS 515

Query: 428 SNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISACSQAETSYGLGK 487
             +  T           P +E +T+   +G+  ++L   +   +S     Q  T++    
Sbjct: 516 PGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSF---GQESTTFHSNP 572

Query: 488 FETRPSEFAEKTTNGHKTDPDCKLSDSCGS-ISKADHSGSLDPTNKGD--AREKKPASPQ 544
             T  + F + TT+    +   ++  S GS  +    + S  P  +G+  A +  PAS  
Sbjct: 573 GSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTH 632

Query: 545 VVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQE-STLEENRQTKTAT 603
                 ST T   +  T       +  G T +   P  S    + E ST+  +    + T
Sbjct: 633 TTPSPPSTATAPVEESTTY----HRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGT 688

Query: 604 SLSLPSDPMGDSSPGSGKKTPSR 626
           +   PS     +S G G+ T SR
Sbjct: 689 T---PSSAHSTTS-GRGESTTSR 707


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 101/510 (19%), Positives = 189/510 (37%), Gaps = 51/510 (10%)

Query: 74  TQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMPANQH 133
           T P+  +P    E+        +P  P+ P  + P A+AP++   ++   T    PA   
Sbjct: 501 TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP--KEPAPTTPKEPAPTT 558

Query: 134 TCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVS--CEFPS 191
             +  P   P     + P+ +   + +      P+KP+ P     +++K+  S  C+ P+
Sbjct: 559 PKEPAP-TTPKETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPA 616

Query: 192 PETIQGTVQT-PVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQP 250
           P T +GT  T P   A       +P   P+G        + ++   P T +    +   P
Sbjct: 617 PTTPKGTAPTTPKEPAPTTPKEPAPTT-PKGT-----APTTLKEPAPTTPKKPAPKELAP 670

Query: 251 SVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEASTMTNQAESEIK 310
           + T  GP  TTS  P PT     P    P   K P P   +    K A T          
Sbjct: 671 TTT-KGPTSTTSDKPAPTT----PKETAPTTPKEPAPTTPK----KPAPTTPETPPPTTS 721

Query: 311 EVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRVICHSSGSHTL 370
           EV +            + E  ++  SP   T  L     P+  E           G  T 
Sbjct: 722 EVST---------PTTTKEPTTIHKSPDESTPELSAEPTPKALENSP-----KEPGVPTT 767

Query: 371 ELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVLKTSSINLVSSNA 430
           +   +T  P+ ++       +  ++     +TA  +  K  +        S I   ++  
Sbjct: 768 KTPAAT-KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 826

Query: 431 QHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISAC--SQAETSYGLGKF 488
             T  +D     +T ++  + A K+  T  +      +++   +A    +A  S      
Sbjct: 827 TSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPK 886

Query: 489 ETRPSEFAEKTTNGHK--TDPDCKLSDSCGSISKADHS-GSLDPTNKGDAREKKPASPQV 545
             +P++  +K T+  K  T P  +   +  +  K   +   L+PT++           + 
Sbjct: 887 PQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSR---------IAEA 937

Query: 546 VKEKESTGTDTSDAKTLLLNPKSQESGGTE 575
           + +  +    T ++K + +NPKS+++GG E
Sbjct: 938 MLQTTTRPNQTPNSKLVEVNPKSEDAGGAE 967



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 124/636 (19%), Positives = 199/636 (31%), Gaps = 75/636 (11%)

Query: 70  EHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMP 129
           E  +T P   +P     ++ AP T   P  P    S+      P+    ++   T    P
Sbjct: 223 EPASTTPKEPTP---TTIKSAPTTPKEPA-PTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 278

Query: 130 ANQHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEF 189
           A   T +  P       T S P      +  T  +  P  P  P              E 
Sbjct: 279 APTTTKEPAP-----TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE- 332

Query: 190 PSPETIQGTVQTPVTAARVVSHSSSPVG----GPEGERQGAICDSEMRSCK------PLT 239
           P+P T +    TP   A       +P       P   ++ A   ++  S        P T
Sbjct: 333 PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 392

Query: 240 RESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEAS 299
            +S  +  K+P+ T +    TT   P PT  T EP+   P       P +   +  KE +
Sbjct: 393 TKSAPTTTKEPAPTTTKSAPTTPKEPSPT-TTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 451

Query: 300 TMTNQAESEI---KEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQE 356
             T +  +     K  P+   + A      +    +  T+P  LT    E  AP   E+ 
Sbjct: 452 PTTPKEPAPTTTKKPAPTTPKEPA-----PTTPKETAPTTPKKLTPTTPEKLAPTTPEK- 505

Query: 357 QLRVICHSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGG 416
                   + +   EL+ +T  P+E +      P      AAA +T  +        P  
Sbjct: 506 -------PAPTTPEELAPTT--PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 556

Query: 417 VL---------KTSSINLVSSNAQHTCKEDGRLAGMTPVREE-----------STAKKLA 456
                      K ++       A  T KE        P  +E           +T  K A
Sbjct: 557 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 616

Query: 457 GTNSSSLKATAIDQISISACSQAETSYGLGKFET-------------RPSEFAEKTTNGH 503
            T       T   + + +   +   +   G   T              P E A  TT G 
Sbjct: 617 PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 676

Query: 504 KTDPDCKLSDSCGSISKADHSGSLDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLL 563
            +    K + +    +         PT         P +P     + ST T T +  T+ 
Sbjct: 677 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI- 735

Query: 564 LNPKSQESGGTESAANPTPSPIRKNQESTLEENRQTKTATSLSLPSDPMGDSSPGSGKKT 623
              KS +    E +A PTP  +  + +       +T  AT   + +     ++    + T
Sbjct: 736 --HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTT 793

Query: 624 PSRSVKASPRRPSRVSEFLKEQKLNVTAAAAQVGLT 659
           P  +  A        +   K  +  +TA   QV  T
Sbjct: 794 PETTTAAPKMTKETATTTEKTTESKITATTTQVTST 829



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 124/619 (20%), Positives = 208/619 (33%), Gaps = 80/619 (12%)

Query: 50  APAEPDLSPRAAAEALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPA 109
           AP     +P    E      +   T P   SP    E         +P  P+ P  + P 
Sbjct: 389 APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 448

Query: 110 ASAPSSAAGRDLIHTPLTMPANQHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEK 169
             AP++   ++   T    PA     +  P   P     + P+     +        PEK
Sbjct: 449 EPAPTTP--KEPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPTTPEK 505

Query: 170 PSCPVGGVLSSSKDQ----VSCEFPSPETIQGTV-----------------QTPVTAARV 208
           P+      L+ +  +     + E P+P T +                     TP   A  
Sbjct: 506 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 565

Query: 209 VSHSSSPVGGPEGERQGAICD-SEMRSCKPLTRESGCSENKQPSVTA------SGPQGTT 261
               ++P   P+G     + + +     KP  +E   +  K+P+ T       + P+GT 
Sbjct: 566 TPKETAPT-TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 624

Query: 262 SVTP-QPTPLT------SEPSACPPGPEKVPLPAQRQMSRFKE-ASTMTNQAESEIKEVP 313
             TP +P P T      + P    P   K P P   +    KE A T T    S   + P
Sbjct: 625 PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 684

Query: 314 SRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRVICHSSGSHTLELS 373
           +            +    +  T+P        +  AP   E         S+ + T E +
Sbjct: 685 A-----------PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPT 733

Query: 374 DSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVLKTSSI---NLVSSNA 430
               +P ES+      P++     +AE T    EN          KT +     + ++  
Sbjct: 734 TIHKSPDEST------PEL-----SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 782

Query: 431 QHTCKEDGRLAGMTPVREESTAKKLAGT--NSSSLKATAIDQISISACSQAETSYGLGKF 488
             T + D R    T        K+ A T   ++  K TA      S  +Q  T + +   
Sbjct: 783 DKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTL 842

Query: 489 ETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSGSLDPTNKGDAREKKPASPQVVKE 548
           +T  +  A K T   KT    ++ +     +K       D      A   KP  P    +
Sbjct: 843 KT--TTLAPKVTTTKKTITTTEIMNKPEETAKPK-----DRATNSKATTPKPQKPTKAPK 895

Query: 549 KESTGTDTSDAKTL--LLNPKSQESGGTESAANPTPSPIRKNQESTLE-ENRQTKTATSL 605
           K    T T   KT+  +  PK+  +    ++  P  +P  +  E+ L+   R  +T  S 
Sbjct: 896 KP---TSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSK 952

Query: 606 SLPSDPMGDSSPGSGKKTP 624
            +  +P  + + G+  +TP
Sbjct: 953 LVEVNPKSEDAGGAEGETP 971



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 34/150 (22%), Positives = 63/150 (42%), Gaps = 14/150 (9%)

Query: 506 DPDCKLSDSCGSISKADHSGSLDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLLLN 565
           D  CK  D C    ++  +   D  NK +  +KKP     V ++  +G D  D K  +  
Sbjct: 46  DAQCKKYDKCCPDYESFCAEVKD--NKKNRTKKKPTPKPPVVDEAGSGLDNGDFK--VTT 101

Query: 566 PKSQESGGTESAANP---TPSPIRKNQESTLEENRQTKTATSLSLPSDPMGDSSPGSGKK 622
           P +  +   + + +P   T  PI  N   +L  N  T   TSL++  +   ++     K+
Sbjct: 102 PDTSTTQHNKVSTSPKITTAKPI--NPRPSLPPNSDTSKETSLTVNKETTVET-----KE 154

Query: 623 TPSRSVKASPRRPSRVSEFLKEQKLNVTAA 652
           T + + + S     + +   + Q +  T+A
Sbjct: 155 TTTTNKQTSTDGKEKTTSAKETQSIEKTSA 184


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 101/510 (19%), Positives = 189/510 (37%), Gaps = 51/510 (10%)

Query: 74   TQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMPANQH 133
            T P+  +P    E+        +P  P+ P  + P A+AP++   ++   T    PA   
Sbjct: 542  TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP--KEPAPTTPKEPAPTT 599

Query: 134  TCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVS--CEFPS 191
              +  P   P     + P+ +   + +      P+KP+ P     +++K+  S  C+ P+
Sbjct: 600  PKEPAP-TTPKETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPA 657

Query: 192  PETIQGTVQT-PVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQP 250
            P T +GT  T P   A       +P   P+G        + ++   P T +    +   P
Sbjct: 658  PTTPKGTAPTTPKEPAPTTPKEPAPTT-PKGT-----APTTLKEPAPTTPKKPAPKELAP 711

Query: 251  SVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEASTMTNQAESEIK 310
            + T  GP  TTS  P PT     P    P   K P P   +    K A T          
Sbjct: 712  TTT-KGPTSTTSDKPAPTT----PKETAPTTPKEPAPTTPK----KPAPTTPETPPPTTS 762

Query: 311  EVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRVICHSSGSHTL 370
            EV +            + E  ++  SP   T  L     P+  E           G  T 
Sbjct: 763  EVST---------PTTTKEPTTIHKSPDESTPELSAEPTPKALENSP-----KEPGVPTT 808

Query: 371  ELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVLKTSSINLVSSNA 430
            +   +T  P+ ++       +  ++     +TA  +  K  +        S I   ++  
Sbjct: 809  KTPAAT-KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 867

Query: 431  QHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISAC--SQAETSYGLGKF 488
              T  +D     +T ++  + A K+  T  +      +++   +A    +A  S      
Sbjct: 868  TSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPK 927

Query: 489  ETRPSEFAEKTTNGHK--TDPDCKLSDSCGSISKADHS-GSLDPTNKGDAREKKPASPQV 545
              +P++  +K T+  K  T P  +   +  +  K   +   L+PT++           + 
Sbjct: 928  PQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSR---------IAEA 978

Query: 546  VKEKESTGTDTSDAKTLLLNPKSQESGGTE 575
            + +  +    T ++K + +NPKS+++GG E
Sbjct: 979  MLQTTTRPNQTPNSKLVEVNPKSEDAGGAE 1008



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 124/636 (19%), Positives = 199/636 (31%), Gaps = 75/636 (11%)

Query: 70  EHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMP 129
           E  +T P   +P     ++ AP T   P  P    S+      P+    ++   T    P
Sbjct: 264 EPASTTPKEPTP---TTIKSAPTTPKEPA-PTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 319

Query: 130 ANQHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEF 189
           A   T +  P       T S P      +  T  +  P  P  P              E 
Sbjct: 320 APTTTKEPAP-----TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE- 373

Query: 190 PSPETIQGTVQTPVTAARVVSHSSSPVG----GPEGERQGAICDSEMRSCK------PLT 239
           P+P T +    TP   A       +P       P   ++ A   ++  S        P T
Sbjct: 374 PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 433

Query: 240 RESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEAS 299
            +S  +  K+P+ T +    TT   P PT  T EP+   P       P +   +  KE +
Sbjct: 434 TKSAPTTTKEPAPTTTKSAPTTPKEPSPT-TTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 492

Query: 300 TMTNQAESEI---KEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQE 356
             T +  +     K  P+   + A      +    +  T+P  LT    E  AP   E+ 
Sbjct: 493 PTTPKEPAPTTTKKPAPTTPKEPA-----PTTPKETAPTTPKKLTPTTPEKLAPTTPEK- 546

Query: 357 QLRVICHSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGG 416
                   + +   EL+ +T  P+E +      P      AAA +T  +        P  
Sbjct: 547 -------PAPTTPEELAPTT--PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 597

Query: 417 VL---------KTSSINLVSSNAQHTCKEDGRLAGMTPVREE-----------STAKKLA 456
                      K ++       A  T KE        P  +E           +T  K A
Sbjct: 598 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 657

Query: 457 GTNSSSLKATAIDQISISACSQAETSYGLGKFET-------------RPSEFAEKTTNGH 503
            T       T   + + +   +   +   G   T              P E A  TT G 
Sbjct: 658 PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 717

Query: 504 KTDPDCKLSDSCGSISKADHSGSLDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLL 563
            +    K + +    +         PT         P +P     + ST T T +  T+ 
Sbjct: 718 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI- 776

Query: 564 LNPKSQESGGTESAANPTPSPIRKNQESTLEENRQTKTATSLSLPSDPMGDSSPGSGKKT 623
              KS +    E +A PTP  +  + +       +T  AT   + +     ++    + T
Sbjct: 777 --HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTT 834

Query: 624 PSRSVKASPRRPSRVSEFLKEQKLNVTAAAAQVGLT 659
           P  +  A        +   K  +  +TA   QV  T
Sbjct: 835 PETTTAAPKMTKETATTTEKTTESKITATTTQVTST 870



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 124/619 (20%), Positives = 208/619 (33%), Gaps = 80/619 (12%)

Query: 50   APAEPDLSPRAAAEALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPA 109
            AP     +P    E      +   T P   SP    E         +P  P+ P  + P 
Sbjct: 430  APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 489

Query: 110  ASAPSSAAGRDLIHTPLTMPANQHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEK 169
              AP++   ++   T    PA     +  P   P     + P+     +        PEK
Sbjct: 490  EPAPTTP--KEPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPTTPEK 546

Query: 170  PSCPVGGVLSSSKDQ----VSCEFPSPETIQGTV-----------------QTPVTAARV 208
            P+      L+ +  +     + E P+P T +                     TP   A  
Sbjct: 547  PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 606

Query: 209  VSHSSSPVGGPEGERQGAICD-SEMRSCKPLTRESGCSENKQPSVTA------SGPQGTT 261
                ++P   P+G     + + +     KP  +E   +  K+P+ T       + P+GT 
Sbjct: 607  TPKETAPT-TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 665

Query: 262  SVTP-QPTPLT------SEPSACPPGPEKVPLPAQRQMSRFKE-ASTMTNQAESEIKEVP 313
              TP +P P T      + P    P   K P P   +    KE A T T    S   + P
Sbjct: 666  PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 725

Query: 314  SRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRVICHSSGSHTLELS 373
            +            +    +  T+P        +  AP   E         S+ + T E +
Sbjct: 726  A-----------PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPT 774

Query: 374  DSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVLKTSSI---NLVSSNA 430
                +P ES+      P++     +AE T    EN          KT +     + ++  
Sbjct: 775  TIHKSPDEST------PEL-----SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 823

Query: 431  QHTCKEDGRLAGMTPVREESTAKKLAGT--NSSSLKATAIDQISISACSQAETSYGLGKF 488
              T + D R    T        K+ A T   ++  K TA      S  +Q  T + +   
Sbjct: 824  DKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTL 883

Query: 489  ETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSGSLDPTNKGDAREKKPASPQVVKE 548
            +T  +  A K T   KT    ++ +     +K       D      A   KP  P    +
Sbjct: 884  KT--TTLAPKVTTTKKTITTTEIMNKPEETAKPK-----DRATNSKATTPKPQKPTKAPK 936

Query: 549  KESTGTDTSDAKTL--LLNPKSQESGGTESAANPTPSPIRKNQESTLE-ENRQTKTATSL 605
            K    T T   KT+  +  PK+  +    ++  P  +P  +  E+ L+   R  +T  S 
Sbjct: 937  KP---TSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSK 993

Query: 606  SLPSDPMGDSSPGSGKKTP 624
             +  +P  + + G+  +TP
Sbjct: 994  LVEVNPKSEDAGGAEGETP 1012



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 34/150 (22%), Positives = 63/150 (42%), Gaps = 14/150 (9%)

Query: 506 DPDCKLSDSCGSISKADHSGSLDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLLLN 565
           D  CK  D C    ++  +   D  NK +  +KKP     V ++  +G D  D K  +  
Sbjct: 87  DAQCKKYDKCCPDYESFCAEVKD--NKKNRTKKKPTPKPPVVDEAGSGLDNGDFK--VTT 142

Query: 566 PKSQESGGTESAANP---TPSPIRKNQESTLEENRQTKTATSLSLPSDPMGDSSPGSGKK 622
           P +  +   + + +P   T  PI  N   +L  N  T   TSL++  +   ++     K+
Sbjct: 143 PDTSTTQHNKVSTSPKITTAKPI--NPRPSLPPNSDTSKETSLTVNKETTVET-----KE 195

Query: 623 TPSRSVKASPRRPSRVSEFLKEQKLNVTAA 652
           T + + + S     + +   + Q +  T+A
Sbjct: 196 TTTTNKQTSTDGKEKTTSAKETQSIEKTSA 225


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 101/510 (19%), Positives = 189/510 (37%), Gaps = 51/510 (10%)

Query: 74   TQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMPANQH 133
            T P+  +P    E+        +P  P+ P  + P A+AP++   ++   T    PA   
Sbjct: 594  TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP--KEPAPTTPKEPAPTT 651

Query: 134  TCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVS--CEFPS 191
              +  P   P     + P+ +   + +      P+KP+ P     +++K+  S  C+ P+
Sbjct: 652  PKEPAP-TTPKETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPA 709

Query: 192  PETIQGTVQT-PVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQP 250
            P T +GT  T P   A       +P   P+G        + ++   P T +    +   P
Sbjct: 710  PTTPKGTAPTTPKEPAPTTPKEPAPTT-PKGT-----APTTLKEPAPTTPKKPAPKELAP 763

Query: 251  SVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEASTMTNQAESEIK 310
            + T  GP  TTS  P PT     P    P   K P P   +    K A T          
Sbjct: 764  TTT-KGPTSTTSDKPAPTT----PKETAPTTPKEPAPTTPK----KPAPTTPETPPPTTS 814

Query: 311  EVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRVICHSSGSHTL 370
            EV +            + E  ++  SP   T  L     P+  E           G  T 
Sbjct: 815  EVST---------PTTTKEPTTIHKSPDESTPELSAEPTPKALENSP-----KEPGVPTT 860

Query: 371  ELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVLKTSSINLVSSNA 430
            +   +T  P+ ++       +  ++     +TA  +  K  +        S I   ++  
Sbjct: 861  KTPAAT-KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 919

Query: 431  QHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISAC--SQAETSYGLGKF 488
              T  +D     +T ++  + A K+  T  +      +++   +A    +A  S      
Sbjct: 920  TSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPK 979

Query: 489  ETRPSEFAEKTTNGHK--TDPDCKLSDSCGSISKADHS-GSLDPTNKGDAREKKPASPQV 545
              +P++  +K T+  K  T P  +   +  +  K   +   L+PT++           + 
Sbjct: 980  PQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSR---------IAEA 1030

Query: 546  VKEKESTGTDTSDAKTLLLNPKSQESGGTE 575
            + +  +    T ++K + +NPKS+++GG E
Sbjct: 1031 MLQTTTRPNQTPNSKLVEVNPKSEDAGGAE 1060



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 124/636 (19%), Positives = 199/636 (31%), Gaps = 75/636 (11%)

Query: 70  EHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMP 129
           E  +T P   +P     ++ AP T   P  P    S+      P+    ++   T    P
Sbjct: 316 EPASTTPKEPTP---TTIKSAPTTPKEPA-PTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 371

Query: 130 ANQHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEF 189
           A   T +  P       T S P      +  T  +  P  P  P              E 
Sbjct: 372 APTTTKEPAP-----TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE- 425

Query: 190 PSPETIQGTVQTPVTAARVVSHSSSPVG----GPEGERQGAICDSEMRSCK------PLT 239
           P+P T +    TP   A       +P       P   ++ A   ++  S        P T
Sbjct: 426 PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 485

Query: 240 RESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEAS 299
            +S  +  K+P+ T +    TT   P PT  T EP+   P       P +   +  KE +
Sbjct: 486 TKSAPTTTKEPAPTTTKSAPTTPKEPSPT-TTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 544

Query: 300 TMTNQAESEI---KEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQE 356
             T +  +     K  P+   + A      +    +  T+P  LT    E  AP   E+ 
Sbjct: 545 PTTPKEPAPTTTKKPAPTTPKEPA-----PTTPKETAPTTPKKLTPTTPEKLAPTTPEK- 598

Query: 357 QLRVICHSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGG 416
                   + +   EL+ +T  P+E +      P      AAA +T  +        P  
Sbjct: 599 -------PAPTTPEELAPTT--PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 649

Query: 417 VL---------KTSSINLVSSNAQHTCKEDGRLAGMTPVREE-----------STAKKLA 456
                      K ++       A  T KE        P  +E           +T  K A
Sbjct: 650 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 709

Query: 457 GTNSSSLKATAIDQISISACSQAETSYGLGKFET-------------RPSEFAEKTTNGH 503
            T       T   + + +   +   +   G   T              P E A  TT G 
Sbjct: 710 PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 769

Query: 504 KTDPDCKLSDSCGSISKADHSGSLDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLL 563
            +    K + +    +         PT         P +P     + ST T T +  T+ 
Sbjct: 770 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI- 828

Query: 564 LNPKSQESGGTESAANPTPSPIRKNQESTLEENRQTKTATSLSLPSDPMGDSSPGSGKKT 623
              KS +    E +A PTP  +  + +       +T  AT   + +     ++    + T
Sbjct: 829 --HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTT 886

Query: 624 PSRSVKASPRRPSRVSEFLKEQKLNVTAAAAQVGLT 659
           P  +  A        +   K  +  +TA   QV  T
Sbjct: 887 PETTTAAPKMTKETATTTEKTTESKITATTTQVTST 922



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 124/619 (20%), Positives = 208/619 (33%), Gaps = 80/619 (12%)

Query: 50   APAEPDLSPRAAAEALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPA 109
            AP     +P    E      +   T P   SP    E         +P  P+ P  + P 
Sbjct: 482  APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 541

Query: 110  ASAPSSAAGRDLIHTPLTMPANQHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEK 169
              AP++   ++   T    PA     +  P   P     + P+     +        PEK
Sbjct: 542  EPAPTTP--KEPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPTTPEK 598

Query: 170  PSCPVGGVLSSSKDQ----VSCEFPSPETIQGTV-----------------QTPVTAARV 208
            P+      L+ +  +     + E P+P T +                     TP   A  
Sbjct: 599  PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 658

Query: 209  VSHSSSPVGGPEGERQGAICD-SEMRSCKPLTRESGCSENKQPSVTA------SGPQGTT 261
                ++P   P+G     + + +     KP  +E   +  K+P+ T       + P+GT 
Sbjct: 659  TPKETAPT-TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 717

Query: 262  SVTP-QPTPLT------SEPSACPPGPEKVPLPAQRQMSRFKE-ASTMTNQAESEIKEVP 313
              TP +P P T      + P    P   K P P   +    KE A T T    S   + P
Sbjct: 718  PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 777

Query: 314  SRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRVICHSSGSHTLELS 373
            +            +    +  T+P        +  AP   E         S+ + T E +
Sbjct: 778  A-----------PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPT 826

Query: 374  DSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVLKTSSI---NLVSSNA 430
                +P ES+      P++     +AE T    EN          KT +     + ++  
Sbjct: 827  TIHKSPDEST------PEL-----SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 875

Query: 431  QHTCKEDGRLAGMTPVREESTAKKLAGT--NSSSLKATAIDQISISACSQAETSYGLGKF 488
              T + D R    T        K+ A T   ++  K TA      S  +Q  T + +   
Sbjct: 876  DKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTL 935

Query: 489  ETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSGSLDPTNKGDAREKKPASPQVVKE 548
            +T  +  A K T   KT    ++ +     +K       D      A   KP  P    +
Sbjct: 936  KT--TTLAPKVTTTKKTITTTEIMNKPEETAKPK-----DRATNSKATTPKPQKPTKAPK 988

Query: 549  KESTGTDTSDAKTL--LLNPKSQESGGTESAANPTPSPIRKNQESTLE-ENRQTKTATSL 605
            K    T T   KT+  +  PK+  +    ++  P  +P  +  E+ L+   R  +T  S 
Sbjct: 989  KP---TSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSK 1045

Query: 606  SLPSDPMGDSSPGSGKKTP 624
             +  +P  + + G+  +TP
Sbjct: 1046 LVEVNPKSEDAGGAEGETP 1064



 Score = 30.0 bits (66), Expect = 8.5
 Identities = 28/125 (22%), Positives = 54/125 (43%), Gaps = 12/125 (9%)

Query: 531 NKGDAREKKPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANP---TPSPIRK 587
           NK +  +KKP     V ++  +G D  D K  +  P +  +   + + +P   T  PI  
Sbjct: 162 NKKNRTKKKPTPKPPVVDEAGSGLDNGDFK--VTTPDTSTTQHNKVSTSPKITTAKPI-- 217

Query: 588 NQESTLEENRQTKTATSLSLPSDPMGDSSPGSGKKTPSRSVKASPRRPSRVSEFLKEQKL 647
           N   +L  N  T   TSL++  +   ++     K+T + + + S     + +   + Q +
Sbjct: 218 NPRPSLPPNSDTSKETSLTVNKETTVET-----KETTTTNKQTSTDGKEKTTSAKETQSI 272

Query: 648 NVTAA 652
             T+A
Sbjct: 273 EKTSA 277


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 101/510 (19%), Positives = 189/510 (37%), Gaps = 51/510 (10%)

Query: 74   TQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMPANQH 133
            T P+  +P    E+        +P  P+ P  + P A+AP++   ++   T    PA   
Sbjct: 635  TTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTP--KEPAPTTPKEPAPTT 692

Query: 134  TCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVS--CEFPS 191
              +  P   P     + P+ +   + +      P+KP+ P     +++K+  S  C+ P+
Sbjct: 693  PKEPAP-TTPKETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPA 750

Query: 192  PETIQGTVQT-PVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQP 250
            P T +GT  T P   A       +P   P+G        + ++   P T +    +   P
Sbjct: 751  PTTPKGTAPTTPKEPAPTTPKEPAPTT-PKGT-----APTTLKEPAPTTPKKPAPKELAP 804

Query: 251  SVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEASTMTNQAESEIK 310
            + T  GP  TTS  P PT     P    P   K P P   +    K A T          
Sbjct: 805  TTT-KGPTSTTSDKPAPTT----PKETAPTTPKEPAPTTPK----KPAPTTPETPPPTTS 855

Query: 311  EVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRVICHSSGSHTL 370
            EV +            + E  ++  SP   T  L     P+  E           G  T 
Sbjct: 856  EVST---------PTTTKEPTTIHKSPDESTPELSAEPTPKALENSP-----KEPGVPTT 901

Query: 371  ELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVLKTSSINLVSSNA 430
            +   +T  P+ ++       +  ++     +TA  +  K  +        S I   ++  
Sbjct: 902  KTPAAT-KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 960

Query: 431  QHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISAC--SQAETSYGLGKF 488
              T  +D     +T ++  + A K+  T  +      +++   +A    +A  S      
Sbjct: 961  TSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPK 1020

Query: 489  ETRPSEFAEKTTNGHK--TDPDCKLSDSCGSISKADHS-GSLDPTNKGDAREKKPASPQV 545
              +P++  +K T+  K  T P  +   +  +  K   +   L+PT++           + 
Sbjct: 1021 PQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSR---------IAEA 1071

Query: 546  VKEKESTGTDTSDAKTLLLNPKSQESGGTE 575
            + +  +    T ++K + +NPKS+++GG E
Sbjct: 1072 MLQTTTRPNQTPNSKLVEVNPKSEDAGGAE 1101



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 124/636 (19%), Positives = 199/636 (31%), Gaps = 75/636 (11%)

Query: 70  EHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMP 129
           E  +T P   +P     ++ AP T   P  P    S+      P+    ++   T    P
Sbjct: 357 EPASTTPKEPTP---TTIKSAPTTPKEPA-PTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 412

Query: 130 ANQHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEF 189
           A   T +  P       T S P      +  T  +  P  P  P              E 
Sbjct: 413 APTTTKEPAP-----TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKE- 466

Query: 190 PSPETIQGTVQTPVTAARVVSHSSSPVG----GPEGERQGAICDSEMRSCK------PLT 239
           P+P T +    TP   A       +P       P   ++ A   ++  S        P T
Sbjct: 467 PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 526

Query: 240 RESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEAS 299
            +S  +  K+P+ T +    TT   P PT  T EP+   P       P +   +  KE +
Sbjct: 527 TKSAPTTTKEPAPTTTKSAPTTPKEPSPT-TTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 585

Query: 300 TMTNQAESEI---KEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQE 356
             T +  +     K  P+   + A      +    +  T+P  LT    E  AP   E+ 
Sbjct: 586 PTTPKEPAPTTTKKPAPTTPKEPA-----PTTPKETAPTTPKKLTPTTPEKLAPTTPEK- 639

Query: 357 QLRVICHSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGG 416
                   + +   EL+ +T  P+E +      P      AAA +T  +        P  
Sbjct: 640 -------PAPTTPEELAPTT--PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 690

Query: 417 VL---------KTSSINLVSSNAQHTCKEDGRLAGMTPVREE-----------STAKKLA 456
                      K ++       A  T KE        P  +E           +T  K A
Sbjct: 691 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPA 750

Query: 457 GTNSSSLKATAIDQISISACSQAETSYGLGKFET-------------RPSEFAEKTTNGH 503
            T       T   + + +   +   +   G   T              P E A  TT G 
Sbjct: 751 PTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 810

Query: 504 KTDPDCKLSDSCGSISKADHSGSLDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLL 563
            +    K + +    +         PT         P +P     + ST T T +  T+ 
Sbjct: 811 TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI- 869

Query: 564 LNPKSQESGGTESAANPTPSPIRKNQESTLEENRQTKTATSLSLPSDPMGDSSPGSGKKT 623
              KS +    E +A PTP  +  + +       +T  AT   + +     ++    + T
Sbjct: 870 --HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTT 927

Query: 624 PSRSVKASPRRPSRVSEFLKEQKLNVTAAAAQVGLT 659
           P  +  A        +   K  +  +TA   QV  T
Sbjct: 928 PETTTAAPKMTKETATTTEKTTESKITATTTQVTST 963



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 124/619 (20%), Positives = 208/619 (33%), Gaps = 80/619 (12%)

Query: 50   APAEPDLSPRAAAEALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPA 109
            AP     +P    E      +   T P   SP    E         +P  P+ P  + P 
Sbjct: 523  APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 582

Query: 110  ASAPSSAAGRDLIHTPLTMPANQHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEK 169
              AP++   ++   T    PA     +  P   P     + P+     +        PEK
Sbjct: 583  EPAPTTP--KEPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPTTPEK 639

Query: 170  PSCPVGGVLSSSKDQ----VSCEFPSPETIQGTV-----------------QTPVTAARV 208
            P+      L+ +  +     + E P+P T +                     TP   A  
Sbjct: 640  PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 699

Query: 209  VSHSSSPVGGPEGERQGAICD-SEMRSCKPLTRESGCSENKQPSVTA------SGPQGTT 261
                ++P   P+G     + + +     KP  +E   +  K+P+ T       + P+GT 
Sbjct: 700  TPKETAPT-TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA 758

Query: 262  SVTP-QPTPLT------SEPSACPPGPEKVPLPAQRQMSRFKE-ASTMTNQAESEIKEVP 313
              TP +P P T      + P    P   K P P   +    KE A T T    S   + P
Sbjct: 759  PTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 818

Query: 314  SRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRVICHSSGSHTLELS 373
            +            +    +  T+P        +  AP   E         S+ + T E +
Sbjct: 819  A-----------PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPT 867

Query: 374  DSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVLKTSSI---NLVSSNA 430
                +P ES+      P++     +AE T    EN          KT +     + ++  
Sbjct: 868  TIHKSPDEST------PEL-----SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 916

Query: 431  QHTCKEDGRLAGMTPVREESTAKKLAGT--NSSSLKATAIDQISISACSQAETSYGLGKF 488
              T + D R    T        K+ A T   ++  K TA      S  +Q  T + +   
Sbjct: 917  DKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTL 976

Query: 489  ETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSGSLDPTNKGDAREKKPASPQVVKE 548
            +T  +  A K T   KT    ++ +     +K       D      A   KP  P    +
Sbjct: 977  KT--TTLAPKVTTTKKTITTTEIMNKPEETAKPK-----DRATNSKATTPKPQKPTKAPK 1029

Query: 549  KESTGTDTSDAKTL--LLNPKSQESGGTESAANPTPSPIRKNQESTLE-ENRQTKTATSL 605
            K    T T   KT+  +  PK+  +    ++  P  +P  +  E+ L+   R  +T  S 
Sbjct: 1030 KP---TSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSK 1086

Query: 606  SLPSDPMGDSSPGSGKKTP 624
             +  +P  + + G+  +TP
Sbjct: 1087 LVEVNPKSEDAGGAEGETP 1105



 Score = 30.0 bits (66), Expect = 8.5
 Identities = 28/125 (22%), Positives = 54/125 (43%), Gaps = 12/125 (9%)

Query: 531 NKGDAREKKPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANP---TPSPIRK 587
           NK +  +KKP     V ++  +G D  D K  +  P +  +   + + +P   T  PI  
Sbjct: 203 NKKNRTKKKPTPKPPVVDEAGSGLDNGDFK--VTTPDTSTTQHNKVSTSPKITTAKPI-- 258

Query: 588 NQESTLEENRQTKTATSLSLPSDPMGDSSPGSGKKTPSRSVKASPRRPSRVSEFLKEQKL 647
           N   +L  N  T   TSL++  +   ++     K+T + + + S     + +   + Q +
Sbjct: 259 NPRPSLPPNSDTSKETSLTVNKETTVET-----KETTTTNKQTSTDGKEKTTSAKETQSI 313

Query: 648 NVTAA 652
             T+A
Sbjct: 314 EKTSA 318


>gi|38201621 eukaryotic translation initiation factor 4 gamma, 1
           isoform 1 [Homo sapiens]
          Length = 1599

 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 96/411 (23%), Positives = 144/411 (35%), Gaps = 83/411 (20%)

Query: 28  PQAASPRHRPALLCKNANG---------FSGAPAEPDLSPRAAAEALMQVCEHETTQ--- 75
           PQ A  R R  +  ++ N           SGA      +P      L      ET Q   
Sbjct: 169 PQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAV 228

Query: 76  ---PDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMPANQ 132
              PD  S G    +   P     PG    P  SQP++ +P          TP   P  +
Sbjct: 229 IVRPDDRSQGAI--IADRPGL---PGPEHSPSESQPSSPSP----------TPSPSPVLE 273

Query: 133 HTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEFPSP 192
                 PG +PN    S+P D++   Q +     P   S   G     S +      P  
Sbjct: 274 ------PGSEPNLAVLSIPGDTMTTIQMSVEESTP--ISRETGEPYRLSPEPTPLAEPIL 325

Query: 193 ETIQGTVQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQPSV 252
           E ++ T+  PV  +     SSSP+  P       +   E     P       SE+ +P V
Sbjct: 326 E-VEVTLSKPVPES---EFSSSPLQAPTPLASHTVEIHEPNGMVP-------SEDLEPEV 374

Query: 253 TASGPQGTTSVTPQPTPLTSEPSACP-------PGPEKVPLPAQRQMSRFKEASTMTNQA 305
            +S         P  +P+   P+A P       P P  V L             +  ++ 
Sbjct: 375 ESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDL-------------SPVSEP 421

Query: 306 ESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRVICHSS 365
           E + KEV +         A  ++ S + +T+PS  +   +E    E  E+E        +
Sbjct: 422 EEQAKEVTAS-------MAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEG---EAGEA 471

Query: 366 GSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAF---QRENKLASL 413
           G    E     L P ES+  P  + Q +++AAAA   A    +R  K+  L
Sbjct: 472 GEAESEKGGEELLPPESTPIPANLSQ-NLEAAAATQVAVSVPKRRRKIKEL 521



 Score = 30.4 bits (67), Expect = 6.5
 Identities = 63/263 (23%), Positives = 86/263 (32%), Gaps = 44/263 (16%)

Query: 66  MQVCEHETTQPDMSSPGV----FNEVQKAPATFNSPGNPQLPGSSQP-------AASAPS 114
           M      T  P   SPG+    F   Q AP  F++P   Q+   SQP        A  PS
Sbjct: 1   MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPS 60

Query: 115 SAAGRDLIHTPLTMPANQHTCQSIPGDQPNAITSSMPEDSLM----------RSQRTSNR 164
           SAA R     P       H   +  G Q   I S +   +             +     +
Sbjct: 61  SAASRVQSAAPARPGPAAHVYPA--GSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQ 118

Query: 165 EQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGTVQTPV-TAARVVSHSSSPVGGPEGER 223
           + P +P  P G    +S  +      +    QG  Q P   A   V  +  P   P+ ER
Sbjct: 119 QYPVQPGAP-GFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRER 177

Query: 224 QGAICDSEMRSCKPLTRE--SGCSENKQPSVTASG-----------PQGTTSVTP----Q 266
           +        +  K +T E  SG      P+   +G           PQ    V P    Q
Sbjct: 178 KTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQ 237

Query: 267 PTPLTSEPSACPPGPEKVPLPAQ 289
              +   P    PGPE  P  +Q
Sbjct: 238 GAIIADRPGL--PGPEHSPSESQ 258


>gi|38201627 eukaryotic translation initiation factor 4 gamma, 1
           isoform 2 [Homo sapiens]
          Length = 1512

 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 96/411 (23%), Positives = 144/411 (35%), Gaps = 83/411 (20%)

Query: 28  PQAASPRHRPALLCKNANG---------FSGAPAEPDLSPRAAAEALMQVCEHETTQ--- 75
           PQ A  R R  +  ++ N           SGA      +P      L      ET Q   
Sbjct: 82  PQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAV 141

Query: 76  ---PDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMPANQ 132
              PD  S G    +   P     PG    P  SQP++ +P          TP   P  +
Sbjct: 142 IVRPDDRSQGAI--IADRPGL---PGPEHSPSESQPSSPSP----------TPSPSPVLE 186

Query: 133 HTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEFPSP 192
                 PG +PN    S+P D++   Q +     P   S   G     S +      P  
Sbjct: 187 ------PGSEPNLAVLSIPGDTMTTIQMSVEESTP--ISRETGEPYRLSPEPTPLAEPIL 238

Query: 193 ETIQGTVQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQPSV 252
           E ++ T+  PV  +     SSSP+  P       +   E     P       SE+ +P V
Sbjct: 239 E-VEVTLSKPVPES---EFSSSPLQAPTPLASHTVEIHEPNGMVP-------SEDLEPEV 287

Query: 253 TASGPQGTTSVTPQPTPLTSEPSACP-------PGPEKVPLPAQRQMSRFKEASTMTNQA 305
            +S         P  +P+   P+A P       P P  V L             +  ++ 
Sbjct: 288 ESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDL-------------SPVSEP 334

Query: 306 ESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRVICHSS 365
           E + KEV +         A  ++ S + +T+PS  +   +E    E  E+E        +
Sbjct: 335 EEQAKEVTAS-------MAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEG---EAGEA 384

Query: 366 GSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAF---QRENKLASL 413
           G    E     L P ES+  P  + Q +++AAAA   A    +R  K+  L
Sbjct: 385 GEAESEKGGEELLPPESTPIPANLSQ-NLEAAAATQVAVSVPKRRRKIKEL 434


>gi|38201625 eukaryotic translation initiation factor 4 gamma, 1
           isoform 3 [Homo sapiens]
          Length = 1435

 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 96/411 (23%), Positives = 144/411 (35%), Gaps = 83/411 (20%)

Query: 28  PQAASPRHRPALLCKNANG---------FSGAPAEPDLSPRAAAEALMQVCEHETTQ--- 75
           PQ A  R R  +  ++ N           SGA      +P      L      ET Q   
Sbjct: 5   PQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAV 64

Query: 76  ---PDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMPANQ 132
              PD  S G    +   P     PG    P  SQP++ +P          TP   P  +
Sbjct: 65  IVRPDDRSQGAI--IADRPGL---PGPEHSPSESQPSSPSP----------TPSPSPVLE 109

Query: 133 HTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEFPSP 192
                 PG +PN    S+P D++   Q +     P   S   G     S +      P  
Sbjct: 110 ------PGSEPNLAVLSIPGDTMTTIQMSVEESTP--ISRETGEPYRLSPEPTPLAEPIL 161

Query: 193 ETIQGTVQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQPSV 252
           E ++ T+  PV  +     SSSP+  P       +   E     P       SE+ +P V
Sbjct: 162 E-VEVTLSKPVPES---EFSSSPLQAPTPLASHTVEIHEPNGMVP-------SEDLEPEV 210

Query: 253 TASGPQGTTSVTPQPTPLTSEPSACP-------PGPEKVPLPAQRQMSRFKEASTMTNQA 305
            +S         P  +P+   P+A P       P P  V L             +  ++ 
Sbjct: 211 ESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDL-------------SPVSEP 257

Query: 306 ESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRVICHSS 365
           E + KEV +         A  ++ S + +T+PS  +   +E    E  E+E        +
Sbjct: 258 EEQAKEVTAS-------MAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEG---EAGEA 307

Query: 366 GSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAF---QRENKLASL 413
           G    E     L P ES+  P  + Q +++AAAA   A    +R  K+  L
Sbjct: 308 GEAESEKGGEELLPPESTPIPANLSQ-NLEAAAATQVAVSVPKRRRKIKEL 357


>gi|38201623 eukaryotic translation initiation factor 4 gamma, 1
           isoform 1 [Homo sapiens]
          Length = 1599

 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 96/411 (23%), Positives = 144/411 (35%), Gaps = 83/411 (20%)

Query: 28  PQAASPRHRPALLCKNANG---------FSGAPAEPDLSPRAAAEALMQVCEHETTQ--- 75
           PQ A  R R  +  ++ N           SGA      +P      L      ET Q   
Sbjct: 169 PQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAV 228

Query: 76  ---PDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMPANQ 132
              PD  S G    +   P     PG    P  SQP++ +P          TP   P  +
Sbjct: 229 IVRPDDRSQGAI--IADRPGL---PGPEHSPSESQPSSPSP----------TPSPSPVLE 273

Query: 133 HTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEFPSP 192
                 PG +PN    S+P D++   Q +     P   S   G     S +      P  
Sbjct: 274 ------PGSEPNLAVLSIPGDTMTTIQMSVEESTP--ISRETGEPYRLSPEPTPLAEPIL 325

Query: 193 ETIQGTVQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQPSV 252
           E ++ T+  PV  +     SSSP+  P       +   E     P       SE+ +P V
Sbjct: 326 E-VEVTLSKPVPES---EFSSSPLQAPTPLASHTVEIHEPNGMVP-------SEDLEPEV 374

Query: 253 TASGPQGTTSVTPQPTPLTSEPSACP-------PGPEKVPLPAQRQMSRFKEASTMTNQA 305
            +S         P  +P+   P+A P       P P  V L             +  ++ 
Sbjct: 375 ESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDL-------------SPVSEP 421

Query: 306 ESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRVICHSS 365
           E + KEV +         A  ++ S + +T+PS  +   +E    E  E+E        +
Sbjct: 422 EEQAKEVTAS-------MAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEG---EAGEA 471

Query: 366 GSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAF---QRENKLASL 413
           G    E     L P ES+  P  + Q +++AAAA   A    +R  K+  L
Sbjct: 472 GEAESEKGGEELLPPESTPIPANLSQ-NLEAAAATQVAVSVPKRRRKIKEL 521



 Score = 30.4 bits (67), Expect = 6.5
 Identities = 63/263 (23%), Positives = 86/263 (32%), Gaps = 44/263 (16%)

Query: 66  MQVCEHETTQPDMSSPGV----FNEVQKAPATFNSPGNPQLPGSSQP-------AASAPS 114
           M      T  P   SPG+    F   Q AP  F++P   Q+   SQP        A  PS
Sbjct: 1   MNKAPQSTGPPPAPSPGLPQPAFPPGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQPPS 60

Query: 115 SAAGRDLIHTPLTMPANQHTCQSIPGDQPNAITSSMPEDSLM----------RSQRTSNR 164
           SAA R     P       H   +  G Q   I S +   +             +     +
Sbjct: 61  SAASRVQSAAPARPGPAAHVYPA--GSQVMMIPSQISYPASQGAYYIPGQGRSTYVVPTQ 118

Query: 165 EQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGTVQTPV-TAARVVSHSSSPVGGPEGER 223
           + P +P  P G    +S  +      +    QG  Q P   A   V  +  P   P+ ER
Sbjct: 119 QYPVQPGAP-GFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAPKRER 177

Query: 224 QGAICDSEMRSCKPLTRE--SGCSENKQPSVTASG-----------PQGTTSVTP----Q 266
           +        +  K +T E  SG      P+   +G           PQ    V P    Q
Sbjct: 178 KTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQ 237

Query: 267 PTPLTSEPSACPPGPEKVPLPAQ 289
              +   P    PGPE  P  +Q
Sbjct: 238 GAIIADRPGL--PGPEHSPSESQ 258


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 130/600 (21%), Positives = 209/600 (34%), Gaps = 81/600 (13%)

Query: 73   TTQPDMSSPG---VFNEVQKAPATFNSPGNPQLPGSSQPAASAP---------------- 113
            +T    S+PG   +  E   A  T  + G+  +P S+   A  P                
Sbjct: 2982 STATPSSTPGTTWILTEQTTAATTTATTGSTAIPSSTPGTAPPPKVLTSTATTPTATSSK 3041

Query: 114  --SSAAGRDLIHTP-LTMPANQHTCQS---IP-------GDQPNAITSSMPEDSLMRSQR 160
              SS++ R     P LT  A + T  S   IP       G  P   T+ M   S +    
Sbjct: 3042 ATSSSSPRTATTLPVLTSTATKSTATSFTPIPSFTLGTTGTLPEQTTTPMATMSTIHPSS 3101

Query: 161  TSNREQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGT--VQTPVTAARVVSHSSSPVGG 218
            T     PE           ++  + +    +P +  GT  + T +T A   + ++ P   
Sbjct: 3102 T-----PETTHTSTVLTTKATTTRATSSMSTPSSTPGTTWILTELTTAATTTAATGPTAT 3156

Query: 219  PEGERQGAICDSEMRSCKPLTRESGCSENKQPS-VTASGPQGTTSVTPQPTPLTSEPSAC 277
            P          +E  +   +T  +G +     +  TA   +  TS    PT ++S  +  
Sbjct: 3157 PSSTPGTTWILTEPSTTATVTVPTGSTATASSTRATAGTLKVLTSTATTPTVISSRATPS 3216

Query: 278  PPGPEKVPLPAQRQMSRFKEASTMTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSP 337
                    LPA R  +    A+++T    S +    +R  Q     A  S  + S ST  
Sbjct: 3217 SSPGTATALPALRSTATTPTATSVTAIPSSSLGTAWTRLSQTTTPTATMSTATPS-STPE 3275

Query: 338  SILTAFLKESRAPEHFEQEQLRVICHSSG-SHTLELSDST----LAPQESSQCPGIMPQV 392
            ++ T+ +  +          +     + G +HT ++  +T     A   SS    + P V
Sbjct: 3276 TVHTSTVLTTTTTTTRATGSVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPV 3335

Query: 393  HIQAAAAESTAFQRENKLASLPG----GVLKTSSINLVSSNAQHTCKEDGRLAGMTPVRE 448
             I      +T        +S+PG      + T++   V++ +  T     + +G TP   
Sbjct: 3336 WISTTTTPTTRGSTVTP-SSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSG-TPPSL 3393

Query: 449  ESTAKKLAGTNSSS--------------LKATAIDQISISACSQAETSYGLGKFETRPSE 494
             +TA  +  T S++              L  TA    + S  S    S  LG   T P  
Sbjct: 3394 TTTATTITATGSTTNPSSTPGTTPIPPVLTTTATTPAATS--STVTPSSALGTTHTPPVP 3451

Query: 495  FAEKTTNGHKTDPDCKLSDSCGSISKADHSGSLDPTNKGDAREKKPASPQVVKEKESTGT 554
                TT+G    P    +      S    SG L     G     +P++  V     +  T
Sbjct: 3452 NTTATTHGRSLPPSSPHTVRTAWTSAT--SGIL-----GTTHITEPST--VTSHTPAATT 3502

Query: 555  DTSDAKTLLLNPKSQESGGTESAANP---TPSPIRKNQESTLEENRQTKTATSLSLPSDP 611
             T+   T  L+     S  TES  +P   TP   R    +T      +KT TS  LPS P
Sbjct: 3503 STTQHSTPALSSPHPSSRTTESPPSPGTTTPGHTRGTSRTTATAT-PSKTRTSTLLPSSP 3561



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 97/450 (21%), Positives = 151/450 (33%), Gaps = 47/450 (10%)

Query: 192  PETIQGT--VQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQ 249
            P +  GT  + T +T     + S+     P          +E  +   +T  +G +    
Sbjct: 2429 PSSTPGTTWILTELTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATAS 2488

Query: 250  PSVTASGPQ--GTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEASTMTNQAES 307
             +   +G     TT+ TP  T   + P + P       LPA R  +    A++ T    S
Sbjct: 2489 STQATAGTPHVSTTATTPTVTSSKATPFSSPG--TATALPALRSTATTPTATSFTAIPSS 2546

Query: 308  EIKEVPSRAWQDAEVQAVASVESRS-----VSTSPSILTAFLKESRAPEHFEQEQLRVIC 362
             +    +R  Q     A  S  + S     V TS  + T                     
Sbjct: 2547 SLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTTTATTTGATGSVATPSSTPGTA 2606

Query: 363  HSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPG----GVL 418
            H++   T   +  T  P  S      +P V I      +T        +S+PG      +
Sbjct: 2607 HTTKVLTTTTTGFTATPSSSPGTARTLP-VWISTTTTPTTRGSTVTP-SSIPGTTHTPTV 2664

Query: 419  KTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSS--------------LK 464
             T++   V++ +  T     + +G TP    +TA  +  T S++              L 
Sbjct: 2665 LTTTTTTVATGSMATPSSSTQTSG-TPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLT 2723

Query: 465  ATAIDQISISACSQAETSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHS 524
             TA    + S  S    S  LG   T P      TT+G    P    +      S    S
Sbjct: 2724 TTATTPAATS--STVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSAT--S 2779

Query: 525  GSLDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANP---T 581
            G+L  T+  +       +P       +  T T+   T  L+     S  TES  +P   T
Sbjct: 2780 GTLGTTHITEPSTGTSHTP-------AATTGTTQHSTPALSSPHPSSRTTESPPSPGTTT 2832

Query: 582  PSPIRKNQESTLEENRQTKTATSLSLPSDP 611
            P   R    +T      +KT TS  LPS P
Sbjct: 2833 PGHTRATSRTTATAT-PSKTRTSTLLPSSP 2861



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 96/404 (23%), Positives = 150/404 (37%), Gaps = 41/404 (10%)

Query: 253  TASGPQ--GTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEASTMTNQAESEIK 310
            TA  P+   TT+ TP  T   + PS+ P       LPA R  +    A+++T    S + 
Sbjct: 1935 TAPPPKVLTTTATTPTVTSSKATPSSSP--GTATALPALRSTATTPTATSVTPIPSSSLG 1992

Query: 311  EVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRVICHSSG-SHT 369
               +R  Q     A  S  + S ST  +  T+ +  + A        +     + G +HT
Sbjct: 1993 TTWTRLSQTTTPTATMSTATPS-STPETAHTSTVLTATATTTGATGSVATPSSTPGTAHT 2051

Query: 370  LELSDST----LAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPG----GVLKTS 421
             ++  +T     A   SS    + P V I      +T        +S+PG      + T+
Sbjct: 2052 TKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTRGSTVTP-SSIPGTTHTATVLTT 2110

Query: 422  SINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTN-----SSSLKATAIDQI-SISA 475
            +   V++ +  T     + +G TP    +TA  +  T      SS+   T I  + + +A
Sbjct: 2111 TTTTVATGSMATPSSSTQTSG-TPPSLTTTATTITATGSTTNPSSTPGTTPIPPVLTTTA 2169

Query: 476  CSQAET------SYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSGSLDP 529
             + A T      S  LG   T P      TT+G    P    +      S    SG L  
Sbjct: 2170 TTPAATSNTVTPSSALGTTHTPPVPNTMATTHGRSLPPSSPHTVRTAWTSAT--SGIL-- 2225

Query: 530  TNKGDAREKKPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQ 589
               G     +P++  V     +  T T+   T  L+     S  TES     PSP     
Sbjct: 2226 ---GTTHITEPST--VTSHTLAATTGTTQHSTPALSSPHPSSRTTES----PPSPGTTTP 2276

Query: 590  ESTLEENRQTKTATSLSLPSDPMGDSSPGSGKKTPSRSVKASPR 633
              T   +R T TAT     +  +  SSP S   T   ++   P+
Sbjct: 2277 GHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTMGCEPQ 2320



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 101/472 (21%), Positives = 162/472 (34%), Gaps = 51/472 (10%)

Query: 191  SPETIQGT--VQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENK 248
            +P +  GT  + T +T     + S+     P          +E  +   +T  +G +   
Sbjct: 3685 TPSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTATVTVPTGSTATA 3744

Query: 249  QPSVTASGPQ--GTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEASTMTNQAE 306
              +   +G     TT+ TP  T   + P + P       LPA R  +    A++ T    
Sbjct: 3745 SSTQATAGTPHVSTTATTPTVTSSKATPFSSPG--TATALPALRSTATTPTATSFTAIPS 3802

Query: 307  SEIKEVPSRAWQDAEVQAVASVESRS----VSTSPSILTAFLKESRAPEHFEQEQLRV-I 361
            S +    +R  Q     A  S  + S     + + ++LT     +RA             
Sbjct: 3803 SSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRATGSVATPSSTPGT 3862

Query: 362  CHSSGSHTLELSDSTLAPQESSQCPGIM--PQVHIQAAAAESTAFQRENKLASLPGGV-- 417
             H++   T   +  T+ P  S   PG    P V I      +T+       +S+PG    
Sbjct: 3863 AHTTKVPTTTTTGFTVTPSSS---PGTARTPPVWISTTTTPTTSGSTVTP-SSVPGTTHT 3918

Query: 418  --LKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSS------------- 462
              + T++   V++ +  T     + +G TP    +TA  +  T S++             
Sbjct: 3919 PTVLTTTTTTVATGSMATPSSSTQTSG-TPPSLITTATTITATGSTTNPSSTPGTTPIPP 3977

Query: 463  -LKATAIDQISISACSQAETSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKA 521
             L  TA    + S  S    S  LG   T P      TT+G    P    +      S  
Sbjct: 3978 VLTTTATTPAATS--STVTPSSALGTTHTPPVPNTTATTHGRSLSPSSPHTVRTAWTSAT 4035

Query: 522  DHSGSLDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPT 581
              SG+L  T+  +       +P          T T+   T  L+     S  TES     
Sbjct: 4036 --SGTLGTTHITEPSTGTSHTPAAT-------TGTTQHSTPALSSPHPSSRTTESP---- 4082

Query: 582  PSPIRKNQESTLEENRQTKTATSLSLPSDPMGDSSPGSGKKTPSRSVKASPR 633
            PSP       T   +R T TAT     +  +  SSP S   T   +    P+
Sbjct: 4083 PSPGTTTPGHTTATSRTTATATPSKTRTSTLLPSSPTSAPITTVVTTGCEPQ 4134



 Score = 38.1 bits (87), Expect = 0.031
 Identities = 121/627 (19%), Positives = 205/627 (32%), Gaps = 58/627 (9%)

Query: 39   LLCKNANGFSGAPAEPDLS-PRAAAEALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSP 97
            + C N       PA    + P +       + E  TT    +S G        P T   P
Sbjct: 4223 VFCCNYGHCPSTPATSSTAMPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTAPPP 4282

Query: 98   GNPQLPGSSQPAAS--APSSAAGRDLIHTP-LTMPANQHTCQSIPGDQPNAI--TSSMPE 152
                 P ++  A S  A SS++ R     P LT  A + T  S+     + +  T ++PE
Sbjct: 4283 KVLTSPATTPTATSSKATSSSSPRTATTLPVLTSTATKSTATSVTPIPSSTLGTTGTLPE 4342

Query: 153  DSLMRSQRTSNREQPEKPSCPVGGVLSSSK---DQVSCEFPSPETIQGT--VQTPVTAAR 207
             +       S       P       + ++K    + +    +P +  GT  + T +T A 
Sbjct: 4343 QTTTPVATMSTIHPSSTPETTHTSTVLTTKATTTRATSSTSTPSSTPGTTWILTELTTAA 4402

Query: 208  VVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENK-----------QPSVTASG 256
              + ++ P   P          +E+ +    T  +G +              +PS TA+ 
Sbjct: 4403 TTTAATGPTATPSSTPGTTWILTELTTTATTTASTGSTATPSSTPGTTWILTEPSTTATV 4462

Query: 257  --PQG------------------TTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFK 296
              P G                  TT+ TP  T   + PS+ P       LPA R  +   
Sbjct: 4463 TVPTGSTATASSTQATAGTPHVSTTATTPTVTSSKATPSSSPG--TATALPALRSTATTP 4520

Query: 297  EASTMTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQE 356
             A++ T    S +    +R  Q     A  S  + S ST  ++ T+ +  + A       
Sbjct: 4521 TATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPS-STPETVHTSTVLTATATTTGATG 4579

Query: 357  QLRVICHSSG-SHTLELSDST----LAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLA 411
             +     + G +HT ++  +T     A   SS    + P V I      +T     +   
Sbjct: 4580 SVATPSSTPGTAHTTKVPTTTTTGFTATPSSSPGTALTPPVWISTTTTPTTTTPTTSGST 4639

Query: 412  SLPGGVLKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQI 471
              P  +  T+    V +    T          +  +   T   L  T ++++ AT     
Sbjct: 4640 VTPSSIPGTTHTARVLTTTTTTVATGSMATPSSSTQTSGTPPSLT-TTATTITATGSTTN 4698

Query: 472  SISACSQAETSYGLGKFETRPSEFAEKTTNGH--KTDPDCKLSDSCGSISKADH-----S 524
              S       +  L    T P+  + K T+    +T     +  S  + S A       S
Sbjct: 4699 PSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLPVLTSTATKSTATSFTPIPS 4758

Query: 525  GSLDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSP 584
             +L  T    A+   P S        ST   T  +  L        +  + +  + T   
Sbjct: 4759 STLWTTWTVPAQTTTPMSTMSTIHTSSTPETTHTSTVLTTTATMTRATNSTATPSSTLGT 4818

Query: 585  IRKNQESTLEENRQTKTATSLSLPSDP 611
             R   E T        T ++ +L S P
Sbjct: 4819 TRILTELTTTATTTAATGSTATLSSTP 4845



 Score = 34.3 bits (77), Expect = 0.45
 Identities = 60/278 (21%), Positives = 88/278 (31%), Gaps = 40/278 (14%)

Query: 46   GFSGAPAEPDLSPRAA--AEALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLP 103
            G +G+ A P  +P  A   + L       T  P  SSPG     +  P   ++   P   
Sbjct: 2591 GATGSVATPSSTPGTAHTTKVLTTTTTGFTATPS-SSPGT---ARTLPVWISTTTTPTTR 2646

Query: 104  GSSQPAASAPSSAAGRDLIHTPLTMPANQHTCQ--SIPGDQPNAITSSMPEDSLMRSQRT 161
            GS+   +S P +       HTP  +     T    S+     +  TS  P      +   
Sbjct: 2647 GSTVTPSSIPGTT------HTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLTTTATTI 2700

Query: 162  SNREQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGTVQTPVTAARVVSHSSS------- 214
            +       PS   G              P P  +  T  TP   +  V+ SS+       
Sbjct: 2701 TATGSTTNPSSTPGTT------------PIPPVLTTTATTPAATSSTVTPSSALGTTHTP 2748

Query: 215  PVGGPEGERQG-AICDSEMRSCKPLTRES-----GCSENKQPSV-TASGPQGTTSVTPQP 267
            PV        G ++  S   + +     +     G +   +PS  T+  P  TT  T   
Sbjct: 2749 PVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTTQHS 2808

Query: 268  TPLTSEPSACPPGPEKVPLPAQRQMSRFKEASTMTNQA 305
            TP  S P       E  P P        +  S  T  A
Sbjct: 2809 TPALSSPHPSSRTTESPPSPGTTTPGHTRATSRTTATA 2846



 Score = 33.5 bits (75), Expect = 0.77
 Identities = 55/263 (20%), Positives = 83/263 (31%), Gaps = 50/263 (19%)

Query: 48   SGAPAEPDLSPRAAAEALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSPG-------NP 100
            +G+ A P  +P  A         H T  P  ++ G       +P T  +P         P
Sbjct: 3850 TGSVATPSSTPGTA---------HTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTP 3900

Query: 101  QLPGSSQPAASAPSSAAGRDLIHTPLTMPANQHTCQ--SIPGDQPNAITSSMPEDSLMRS 158
               GS+   +S P +       HTP  +     T    S+     +  TS  P   +  +
Sbjct: 3901 TTSGSTVTPSSVPGTT------HTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITTA 3954

Query: 159  QRTSNREQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGTVQTPVTAARVVSHSSS---- 214
               +       PS   G              P P  +  T  TP   +  V+ SS+    
Sbjct: 3955 TTITATGSTTNPSSTPGTT------------PIPPVLTTTATTPAATSSTVTPSSALGTT 4002

Query: 215  ---PVGGPEGERQG-AICDSEMRSCKPLTRES-----GCSENKQPSV-TASGPQGTTSVT 264
               PV        G ++  S   + +     +     G +   +PS  T+  P  TT  T
Sbjct: 4003 HTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPSTGTSHTPAATTGTT 4062

Query: 265  PQPTPLTSEPSACPPGPEKVPLP 287
               TP  S P       E  P P
Sbjct: 4063 QHSTPALSSPHPSSRTTESPPSP 4085



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 55/258 (21%), Positives = 81/258 (31%), Gaps = 36/258 (13%)

Query: 46   GFSGAPAEPDLSPRAAAEALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGS 105
            G +G+ A P  +P  A         H T  P  ++ G            +SPG    P  
Sbjct: 2034 GATGSVATPSSTPGTA---------HTTKVPTTTTTGF------TATPSSSPGTALTPPV 2078

Query: 106  SQPAASAPSSAAGRDLIHTPLTMPANQHTCQSIPGDQPNAITSSM--PEDSLMRSQRTSN 163
                 + P++   R    TP ++P   HT   +        T SM  P  S   S    +
Sbjct: 2079 WISTTTTPTT---RGSTVTPSSIPGTTHTATVLTTTTTTVATGSMATPSSSTQTSGTPPS 2135

Query: 164  REQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGTVQTPVTAARVVSHSSSPVGGPEGER 223
                       G   + S    +   P P  +  T  TP   +  V+ SS+         
Sbjct: 2136 LTTTATTITATGSTTNPSSTPGTT--PIPPVLTTTATTPAATSNTVTPSSALGTTHTPPV 2193

Query: 224  QGAICDSEMRSCKPLTRES-------------GCSENKQPS-VTASGPQGTTSVTPQPTP 269
               +  +  RS  P +  +             G +   +PS VT+     TT  T   TP
Sbjct: 2194 PNTMATTHGRSLPPSSPHTVRTAWTSATSGILGTTHITEPSTVTSHTLAATTGTTQHSTP 2253

Query: 270  LTSEPSACPPGPEKVPLP 287
              S P       E  P P
Sbjct: 2254 ALSSPHPSSRTTESPPSP 2271



 Score = 32.3 bits (72), Expect = 1.7
 Identities = 95/499 (19%), Positives = 163/499 (32%), Gaps = 80/499 (16%)

Query: 14   SLIAASGKEDDLGEPQAASPRHRPALLCKNANGFSGAPAEPDLSPRAAAEALMQVCEHET 73
            S   AS  +   G P  ++    P +    A   S +P      P   + A        T
Sbjct: 4468 STATASSTQATAGTPHVSTTATTPTVTSSKATP-SSSPGTATALPALRSTATTPTATSFT 4526

Query: 74   TQPDMSSPGVFNEVQKAP------ATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTPLT 127
              P  S    +  + +        +T      P+   +S    +  ++      + TP +
Sbjct: 4527 AIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETVHTSTVLTATATTTGATGSVATPSS 4586

Query: 128  MPANQHTCQSIPGDQPNAIT---SSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQ 184
             P   HT + +P       T   SS P  +L      S    P           +++   
Sbjct: 4587 TPGTAHTTK-VPTTTTTGFTATPSSSPGTALTPPVWISTTTTP-----------TTTTPT 4634

Query: 185  VSCEFPSPETIQGTVQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGC 244
             S    +P +I GT  T    ARV++ +++ V               M +    T+ SG 
Sbjct: 4635 TSGSTVTPSSIPGTTHT----ARVLTTTTTTVA-----------TGSMATPSSSTQTSGT 4679

Query: 245  SEN---KQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKE---- 297
              +      ++TA+G     S TP  TP+T   ++    P      A    S        
Sbjct: 4680 PPSLTTTATTITATGSTTNPSSTPGTTPITPVLTSTATTPAATSSKATSSSSPRTATTLP 4739

Query: 298  --ASTMTNQAESEIKEVPSRA-WQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFE 354
               ST T    +    +PS   W    V A  +    ++ST        +  S  P   E
Sbjct: 4740 VLTSTATKSTATSFTPIPSSTLWTTWTVPAQTTTPMSTMST--------IHTSSTP---E 4788

Query: 355  QEQLRVICHSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQA---AAAESTAFQRENKLA 411
                  +  ++ + T   ++ST  P  +     I+ ++   A   AA  STA      L+
Sbjct: 4789 TTHTSTVLTTTATMT-RATNSTATPSSTLGTTRILTELTTTATTTAATGSTA-----TLS 4842

Query: 412  SLPGGVLKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQI 471
            S PG     +  + +++              M P    +TA    GT  +    T +  +
Sbjct: 4843 STPGTTWILTEPSTIAT-------------VMVPTGSTATASSTLGTAHTPKVVTTMATM 4889

Query: 472  SISACSQAETSYGLGKFET 490
              +  S   +S  +G   T
Sbjct: 4890 PTATASTVPSSSTVGTTRT 4908



 Score = 30.0 bits (66), Expect = 8.5
 Identities = 100/461 (21%), Positives = 146/461 (31%), Gaps = 96/461 (20%)

Query: 100  PQLPGSSQPAASAPSSAAGRDLIHTPLTMPA-------NQHTCQSIPG------DQPNAI 146
            P  P +S  A   PSS  G   I T LT  A       +  T  S PG      +     
Sbjct: 3675 PSTPATSSTAT--PSSTPGTTWILTKLTTTATTTESTGSTATPSSTPGTTWILTEPSTTA 3732

Query: 147  TSSMPEDSLMRSQRT-SNREQPEKPSCPVGGVLSSSKDQVSCEFPSPET------IQGTV 199
            T ++P  S   +  T +    P   +      ++SSK   +  F SP T      ++ T 
Sbjct: 3733 TVTVPTGSTATASSTQATAGTPHVSTTATTPTVTSSK---ATPFSSPGTATALPALRSTA 3789

Query: 200  QTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQG 259
             TP   +     SSS         Q     + M +  P +       +   + TA+  + 
Sbjct: 3790 TTPTATSFTAIPSSSLGTTWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTTTATTTRA 3849

Query: 260  TTSV-TPQPTPLTSE---------------PSACPPGPEKVPLPAQRQMSRFKEASTMTN 303
            T SV TP  TP T+                PS+ P      P+      +     ST+T 
Sbjct: 3850 TGSVATPSSTPGTAHTTKVPTTTTTGFTVTPSSSPGTARTPPVWISTTTTPTTSGSTVTP 3909

Query: 304  QAESEIKEVPSRAWQDAEVQAVASVESRSVSTS-----PSILTAFLKESRAPEHFEQEQL 358
             +       P+         A  S+ + S ST      PS++T                 
Sbjct: 3910 SSVPGTTHTPTVLTTTTTTVATGSMATPSSSTQTSGTPPSLITT---------------- 3953

Query: 359  RVICHSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVL 418
                    + T+  + ST  P   S  PG  P   +    A + A        S   G  
Sbjct: 3954 --------ATTITATGSTTNP---SSTPGTTPIPPVLTTTATTPAATSSTVTPSSALGTT 4002

Query: 419  KTSSI---------NLVSSNAQHTCKEDGRLA-----GMTPVREESTAKKLAGTNSSSLK 464
             T  +           +S ++ HT +     A     G T + E ST     GT+ +   
Sbjct: 4003 HTPPVPNTTATTHGRSLSPSSPHTVRTAWTSATSGTLGTTHITEPST-----GTSHTPAA 4057

Query: 465  ATAIDQISISACSQAETSYGLGKFETRPSEFAEKTTNGHKT 505
             T   Q S  A S    S    +    P      TT GH T
Sbjct: 4058 TTGTTQHSTPALSSPHPSSRTTESPPSPG----TTTPGHTT 4094


>gi|41281612 zinc finger protein 828 [Homo sapiens]
          Length = 812

 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 89/351 (25%), Positives = 134/351 (38%), Gaps = 60/351 (17%)

Query: 71  HETTQPDMSSPGVFNEVQKAPATFNSPGN-PQLPGSSQPAASAPSSAAGRDLIHTPL--- 126
           ++ T P  S P    E QK P     P + P L   +Q   S  S  + +    TPL   
Sbjct: 100 NKETDPVKSPP--LPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQ 157

Query: 127 -----TMPANQHTCQSIPGDQPNAITSSMPEDSL--MRSQRTSNREQPEK----PSCP-- 173
                  P  Q    S    +P +++S  P  S+    SQ+ +    PE     P  P  
Sbjct: 158 KPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPES 217

Query: 174 VGGVLSSSKDQVSCEFPSPETI----QGTVQTPVTAARVVSHSSSPVGGPEGERQGAICD 229
           V   LS+ K Q    FP  ET+      + ++PV AA       SP   PE  +      
Sbjct: 218 VKATLSNPKPQKQSHFP--ETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSA---- 271

Query: 230 SEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTP-QPTPLTSEPSACPPGPEKVPLPA 288
              R+  P  R+   SE+ +P      P    S  P +P P  S P +  PGP   P P 
Sbjct: 272 ---RTTSPEPRKPSPSESPEP----WKPFPAVSPEPRRPAPAVS-PGSWKPGPPGSPRPW 323

Query: 289 QRQMSR----FKEASTMTNQAESEIKEVPSRA---WQDAEVQAVASVESRSVSTSPSILT 341
           +   S     +K A    + +    K +PS +   W+     + AS +S SVS S     
Sbjct: 324 KSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPS----- 378

Query: 342 AFLKESRAPEHFEQEQLRVICHSSGSHTLELSDSTLAPQESSQCPGIMPQV 392
           ++     +PE ++          SG   L  +  TL+P+     P + P++
Sbjct: 379 SWKSPPASPESWK----------SGPPELRKTAPTLSPEHWKAVPPVSPEL 419



 Score = 34.3 bits (77), Expect = 0.45
 Identities = 31/101 (30%), Positives = 48/101 (47%), Gaps = 8/101 (7%)

Query: 23  DDLGEPQAASPRHRPALLCKNANGFSGAPA---EPDLSPRAAAEALMQVCEHETTQPDMS 79
           + LG P A+SP     +L  +   +  +PA   E   S R  +    +    E+ +P   
Sbjct: 235 ETLGPPSASSPES--PVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKP 292

Query: 80  SPGVFNEVQKAPATFNSPGN--PQLPGSSQPAASAPSSAAG 118
            P V  E ++ PA   SPG+  P  PGS +P  S PS+++G
Sbjct: 293 FPAVSPEPRR-PAPAVSPGSWKPGPPGSPRPWKSNPSASSG 332


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 152/731 (20%), Positives = 257/731 (35%), Gaps = 143/731 (19%)

Query: 2    GTVPDPLRSAKTSLIAASGKEDDLGEPQAASPRHRPALLCKNANGFSGAPAEPDLSPRAA 61
            G+ P  L    T    +SG  +    P + +   +P L  K+   +S +P  PD +   A
Sbjct: 519  GSTPSVLVGDSTPSPISSGSMETTALPGSTT---KPGLSEKSTTFYS-SPRSPDTTHLPA 574

Query: 62   AEALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDL 121
            +     V E  TT    S PG       +  T   PG+  +PG SQ + ++ SS    D 
Sbjct: 575  SMTSSGVSEESTTSH--SRPG-------STHTTAFPGSTTMPGLSQESTASHSSPGPTDT 625

Query: 122  IHTPLTMPANQ-----HTCQSIPGDQPNAIT-----------SSMPEDSLMRSQRT---- 161
              +P +  A+       T  S PG     +            +SMP  S  RS  T    
Sbjct: 626  TLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSP 685

Query: 162  ------------------SNREQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGT-VQTP 202
                              SN  +P  P+       S+  +  +    SP +I  T +   
Sbjct: 686  AGSTTRQGESTTFHSWPSSNDTRPAPPT-----TTSAFVEPSTTSHGSPSSIPTTHISAR 740

Query: 203  VTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTS 262
             T + +V  S++    P   +     +S+  S +    ES  S +      +S P  T++
Sbjct: 741  STTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRG--EESTTSHSSTTHTISSAPSTTSA 798

Query: 263  VTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEASTMTNQAESEIKEVPSRAWQDAEV 322
            +  +PT   S P +                + F ++ST + ++E  I    S + QDA  
Sbjct: 799  LVEEPTSYHSSPGSTAT-------------THFPDSSTTSGRSEESIA---SHSSQDATG 842

Query: 323  QAVASVESRSV-----STSPSILTAFLKESRAPEHFEQEQLRVICHSSGSHTLELSDSTL 377
              V    S +      ST+  I +  ++ +  P       L     S+  H+   S +T 
Sbjct: 843  TIVLPARSTNSVLLGESTTSPISSGSMETTALPGSTTTPGLSE--RSTTFHSSPRSPATT 900

Query: 378  APQESSQCPGIMPQV---HIQAAAAESTAFQRENKLASLPGGVLKTSSINLVSSNAQHTC 434
                S+   G+  +    H +  +  +TAF      ++   G+ + S+ +  S  +  T 
Sbjct: 901  LSPASTTSSGVSEESTTSHSRPGSTHTTAFPD----STTTPGLSRHSTTSHSSPGSTDTT 956

Query: 435  KEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISA-CSQAETSY---------G 484
                     T +  E T   ++   S S + TA+   + +A  S+  T++          
Sbjct: 957  LLPASTT--TXLVGEPTTSPIS---SGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTT 1011

Query: 485  LGKFETRPSEFAEKTTNGHKTDPDCKLSDSCGSI--------SKADHS--GSLDPTNKGD 534
            L    T  S  +E++T  H        +   GS         S A HS  GS D T    
Sbjct: 1012 LSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPR 1071

Query: 535  AREKKPASPQVVKEKESTGT-------DTSDAKTLL--LNPKSQESGGTESAANPTPSPI 585
            +       P+        G+       D + A  LL    P    +G   +  +P  S  
Sbjct: 1072 STTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPRTTLSPAGSTT 1131

Query: 586  RKNQESTLEENRQTK-------TATSL-------------SLPSDPMGDSSPGSGKKTPS 625
            R+ + +T +    +K       T TS              S+P+     SS   G+   S
Sbjct: 1132 RQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSIPTTHFSASSTTFGRSEES 1191

Query: 626  RSVKASPRRPS 636
             +V +SP  P+
Sbjct: 1192 TTVHSSPVAPA 1202



 Score = 34.7 bits (78), Expect = 0.35
 Identities = 87/397 (21%), Positives = 132/397 (33%), Gaps = 77/397 (19%)

Query: 90   APATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMPANQHTCQSIPGDQPNAITSS 149
            APAT  SP      G  + + +  SS      +H P +  A+  + +S         T S
Sbjct: 1200 APATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTIS 1259

Query: 150  MPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGTVQTPVTAARVV 209
             P      S  ++  E+P       G + ++        FP   T  G      +     
Sbjct: 1260 SPP-----STTSALVEEPTSYHSSPGSIATT-------HFPESSTTSGR-----SEESTA 1302

Query: 210  SHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQPSVT---ASGPQGTTSVTPQ 266
            SHSS    G                  PL      S     S T   + G   TT  +  
Sbjct: 1303 SHSSPDTNG----------------ITPLPAHFTTSGRIAESTTFYISPGSMETTLASTA 1346

Query: 267  PTPLTSEPS----ACPPGPEKVPLPAQRQMSRFK-EASTMTNQAES-EIKEVPSRAWQDA 320
             TP  S  S    +    P++   PA    S    E +++ +QAES      P+      
Sbjct: 1347 TTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSG 1406

Query: 321  EVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRVICHSSGSHTLELSDSTLAPQ 380
              Q   +  S+  ST  ++    +  S   + F         HS     L    ST++P 
Sbjct: 1407 LSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTP------HSQPGSAL----STVSP- 1455

Query: 381  ESSQCPGIMPQ---VHIQAAAAESTAFQRENKLA----------SLPG-------GVLKT 420
             S+  PG+  +    +    + E+TAF   N ++            PG         L T
Sbjct: 1456 ASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTT 1515

Query: 421  SSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAG 457
            + I    S A H+  +     G TP+   STA  L G
Sbjct: 1516 TDIG-QESTAFHSSSD---ATGTTPLPARSTASDLVG 1548


>gi|38201619 eukaryotic translation initiation factor 4 gamma, 1
           isoform 4 [Homo sapiens]
          Length = 1403

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 77/327 (23%), Positives = 120/327 (36%), Gaps = 63/327 (19%)

Query: 97  PGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMPANQHTCQSIPGDQPNAITSSMPEDSLM 156
           PG    P  SQP++ +P          TP   P  +      PG +PN    S+P D++ 
Sbjct: 52  PGPEHSPSESQPSSPSP----------TPSPSPVLE------PGSEPNLAVLSIPGDTMT 95

Query: 157 RSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGTVQTPVTAARVVSHSSSPV 216
             Q +     P   S   G     S +      P  E ++ T+  PV  +     SSSP+
Sbjct: 96  TIQMSVEESTP--ISRETGEPYRLSPEPTPLAEPILE-VEVTLSKPVPES---EFSSSPL 149

Query: 217 GGPEGERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSA 276
             P       +   E     P       SE+ +P V +S         P  +P+   P+A
Sbjct: 150 QAPTPLASHTVEIHEPNGMVP-------SEDLEPEVESSPELAPPPACPSESPVPIAPTA 202

Query: 277 CP-------PGPEKVPLPAQRQMSRFKEASTMTNQAESEIKEVPSRAWQDAEVQAVASVE 329
            P       P P  V L             +  ++ E + KEV +         A  ++ 
Sbjct: 203 QPEELLNGAPSPPAVDL-------------SPVSEPEEQAKEVTAS-------MAPPTIP 242

Query: 330 SRSVSTSPSILTAFLKESRAPEHFEQEQLRVICHSSGSHTLELSDSTLAPQESSQCPGIM 389
           S + +T+PS  +   +E    E  E+E        +G    E     L P ES+  P  +
Sbjct: 243 SATPATAPSATSPAQEEEMEEEEEEEEG---EAGEAGEAESEKGGEELLPPESTPIPANL 299

Query: 390 PQVHIQAAAAESTAF---QRENKLASL 413
            Q +++AAAA   A    +R  K+  L
Sbjct: 300 SQ-NLEAAAATQVAVSVPKRRRKIKEL 325


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 96/378 (25%), Positives = 141/378 (37%), Gaps = 64/378 (16%)

Query: 261  TSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEASTMTNQAESEIKEVPSRAWQDA 320
            TS     TP TS  + C    EK+    Q     + E S +   AE   K+ PS A QD 
Sbjct: 2027 TSTKTTRTPDTS--TYCYETAEKITRTPQASTYSY-ETSDLCYTAE---KKSPSEARQDV 2080

Query: 321  EVQAVASVESRSVST--SPSILTAFLKESRAPEHFEQEQLRVICHSSGSHTLELSDSTLA 378
            ++  V+S E +   T  SPS +     E  A E   +E  + +  S G+           
Sbjct: 2081 DLCLVSSCEYKHPKTELSPSFINPNPLEWFASEEPTEESEKPLTQSGGA-----PPPPGG 2135

Query: 379  PQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVLKTSSINLVSSNAQHTCKEDG 438
             Q+  QC    P   +  +A   T      +    P     T+  N+ S +   T   D 
Sbjct: 2136 KQQGRQCDE-TPPTSVSESAPSQTDSDVPPETEECPS---ITADANIDSEDESETIPTDK 2191

Query: 439  RLA------GMTPVREESTAKKLAGTNSSSLKATAIDQISISACSQAETSYGLGKFETRP 492
             +          PV++ S + +    +    +A AI+Q              LGK     
Sbjct: 2192 TVTYKHMDPPPAPVQDRSPSPRHPDVSMVDPEALAIEQ-------------NLGK--ALK 2236

Query: 493  SEFAEKTTNGHKTDPDCKLSDSCGSISKADHSGSLDPTNKGDAREKK-PASPQVVKEKES 551
             +  EKT       P  K   S              P  K D + K   ASP+    KES
Sbjct: 2237 KDLKEKTKT---KKPGTKTKSS-------------SPVKKSDGKSKPLAASPKPAGLKES 2280

Query: 552  TGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQESTLEENRQTKTATSLSL-PSD 610
                 SD  + + +PK +ES   E AA PT +P  K      E++++TK A + S   S 
Sbjct: 2281 -----SDKVSRVASPKKKES--VEKAAKPTTTPEVKAARGE-EKDKETKNAANASASKSA 2332

Query: 611  PMGDSSPGSGKKTPSRSV 628
                + PG+ K T S +V
Sbjct: 2333 KTATAGPGTTKTTKSSAV 2350



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 137/657 (20%), Positives = 239/657 (36%), Gaps = 99/657 (15%)

Query: 73   TTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMPANQ 132
            T Q    SPG      + PA+  S  +  LPG S+  A+A       D            
Sbjct: 1069 TKQLGAQSPG------REPAS--SIHDETLPGGSESEATASDEENREDQPEEFTATSGYT 1120

Query: 133  HTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEFPSP 192
             +   I  +       S P D +  S  T+N E+ E PS     +        S E+  P
Sbjct: 1121 QSTIEISSEPTPMDEMSTPRDVM--SDETNN-EETESPSQEFVNITKYESSLYSQEYSKP 1177

Query: 193  ETI-------QGTVQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCS 245
              +       +G+ +T  T  +  + S+S +  P    +     S +R       ++ CS
Sbjct: 1178 ADVTPLNGFSEGS-KTDATDGKDYNASASTISPPSSMEEDKFSRSALR-------DAYCS 1229

Query: 246  ENKQPSVTASGPQGTTSVTPQPTPLTSEPSACP--PGP-EKVPLPAQRQMSRFKEASTMT 302
            E K  S T       ++V+ +    +  PS  P  P P EK PL  +R ++     + + 
Sbjct: 1230 EVKA-STTLDIKDSISAVSSEKVSPSKSPSLSPSPPSPLEKTPL-GERSVNFSLTPNEIK 1287

Query: 303  NQAESEIKEVPSRAWQDAEVQAVASVESRS---VSTSPSIL-----TAFL------KESR 348
              AE+E+  V     Q+   +  AS E ++   VS S S+      T +       K S 
Sbjct: 1288 VSAEAEVAPVSPEVTQEVVEEHCASPEDKTLEVVSPSQSVTGSAGHTPYYQSPTDEKSSH 1347

Query: 349  APEHFEQEQLRVIC------------HSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQA 396
             P    ++   V               +S S   E    + +P E    P   P +    
Sbjct: 1348 LPTEVIEKPPAVPVSFEFSDAKDENERASVSPMDEPVPDSESPIEKVLSPLRSPPLIGSE 1407

Query: 397  AAAES--------------TAFQRENKLASLPGGVLKTSSINLVSSNAQHTCKEDGRLAG 442
            +A ES              + F+ ++     P  V   S ++ ++S + +  K++G+   
Sbjct: 1408 SAYESFLSADDKASGRGAESPFEEKSGKQGSPDQV---SPVSEMTSTSLYQDKQEGKSTD 1464

Query: 443  MTPVREESTAKKLAG--TNSSSLKATAIDQISISACSQAE---TSYGLGKFETRPSEFAE 497
              P++E+   +K        SS  A A+D+  +   S  +   + +G  K +T+ S  +E
Sbjct: 1465 FAPIKEDFGQEKKTDDVEAMSSQPALALDERKLGDVSPTQIDVSQFGSFKEDTKMS-ISE 1523

Query: 498  KTTNGHKTDP--------DCKLSDSCGSISKADHSGSLDPTNKGDAREKKPASPQVVKEK 549
             T +     P             +   S+S A  + S  P    D  +  P+    V   
Sbjct: 1524 GTVSDKSATPVDEGVAEDTYSHMEGVASVSTASVATSSFPEPTTD--DVSPSLHAEVGSP 1581

Query: 550  ESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQESTLEENRQTKTATSLSLPS 609
             ST  D S + +++  P + +      +    P P+     S    +   KTA S +   
Sbjct: 1582 HSTEVDDSLSVSVVQTPTTFQETEMSPSKEECPRPM-----SISPPDFSPKTAKSRTPVQ 1636

Query: 610  DPMGDSSPGS---GKKTPSRSVKASPRRPSRVSEFLKEQKLNVTA-AAAQVGLTPGD 662
            D   + S  S   G+++P +S+     R S     +    L++T     +V  +P D
Sbjct: 1637 DHRSEQSSMSIEFGQESPEQSLAMDFSRQSPDHPTVGAGVLHITENGPTEVDYSPSD 1693



 Score = 31.2 bits (69), Expect = 3.8
 Identities = 55/277 (19%), Positives = 96/277 (34%), Gaps = 19/277 (6%)

Query: 423  INLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAI----------DQIS 472
            +N+    +    +E  + A +TP+   S   K   T+     A+A           D+ S
Sbjct: 1160 VNITKYESSLYSQEYSKPADVTPLNGFSEGSKTDATDGKDYNASASTISPPSSMEEDKFS 1219

Query: 473  ISA-----CSQAETSYGLGKFETRPSEFAEKTTNGHKTD----PDCKLSDSCGSISKADH 523
             SA     CS+ + S  L   ++  +  +EK +          P   L  +       + 
Sbjct: 1220 RSALRDAYCSEVKASTTLDIKDSISAVSSEKVSPSKSPSLSPSPPSPLEKTPLGERSVNF 1279

Query: 524  SGSLDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPS 583
            S + +        E  P SP+V +E       + + KTL +   SQ   G+        S
Sbjct: 1280 SLTPNEIKVSAEAEVAPVSPEVTQEVVEEHCASPEDKTLEVVSPSQSVTGSAGHTPYYQS 1339

Query: 584  PIRKNQESTLEENRQTKTATSLSLPSDPMGDSSPGSGKKTPSRSVKASPRRPSRVSEFLK 643
            P  +       E  +   A  +S       D +  +        V  S     +V   L+
Sbjct: 1340 PTDEKSSHLPTEVIEKPPAVPVSFEFSDAKDENERASVSPMDEPVPDSESPIEKVLSPLR 1399

Query: 644  EQKLNVTAAAAQVGLTPGDKKKQLGADSKLQLKQSKR 680
               L  + +A +  L+  DK    GA+S  + K  K+
Sbjct: 1400 SPPLIGSESAYESFLSADDKASGRGAESPFEEKSGKQ 1436


>gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]
          Length = 587

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 112/538 (20%), Positives = 180/538 (33%), Gaps = 55/538 (10%)

Query: 73  TTQPDMSSPGVFNEVQKAPATFNS-PGNP---QLPGSSQPAASAPSSAAG---RDLIHTP 125
           TT    S+P   + + + P +++S PG+      P SS  +  +  S A    +D   T 
Sbjct: 23  TTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGT- 81

Query: 126 LTMPANQHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQV 185
           + +PA   T   +     + I+S   E + +    T+               LS      
Sbjct: 82  IVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPG-------------LSEKSTTF 128

Query: 186 SCEFPSPETIQGTVQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCS 245
                SP T      T  T++ V   S++    P      A  DS   +   L+R S  S
Sbjct: 129 HSSPRSPATTLSPAST--TSSGVSEESTTSHSRPGSTHTTAFPDST--TTPGLSRHSTTS 184

Query: 246 ENKQPSV-TASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPL-PAQRQMSRFKEASTMTN 303
            +   S  T   P  TT+  P     TS  S   PG     L P       F + ST  +
Sbjct: 185 HSSPGSTDTTLLPASTTTSGPSQESTTSHSS---PGSTDTALSPGSTTALSFGQESTTFH 241

Query: 304 QAESEIKEV--PSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRVI 361
            +         P        V+A   V S + S   ++  A    S      + E     
Sbjct: 242 SSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPA----SSTSPGLQGESTAFQ 297

Query: 362 CHSSGSHTLELSDSTL-APQESS----QCPGIMPQVHIQAAAAESTAFQRENKLASLP-- 414
            H + +HT     ST  AP E S    + PG  P  H  A++  S   ++     S P  
Sbjct: 298 THPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDA 357

Query: 415 ------------GGVLKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSS 462
                        GV + SS +     + HT             +E +T+    G+  ++
Sbjct: 358 SGTTPSSAHSTTSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEAT 417

Query: 463 LKATAIDQISISACSQAETSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKAD 522
           L  T     + +A  +  T+Y      T  + F+  +T   +++    +  S GS     
Sbjct: 418 LDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGSTETTA 477

Query: 523 HSGSLDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANP 580
             GS       +      +SP+      S  + TS   +          G T + A P
Sbjct: 478 LPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFP 535



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 78/428 (18%), Positives = 150/428 (35%), Gaps = 70/428 (16%)

Query: 241 ESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEAST 300
           ES  S +      +S P  T+++  +PT   S P +                + F ++ST
Sbjct: 15  ESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGS-------------TATTHFPDSST 61

Query: 301 MTNQAESEIKEVPSRAWQDAEVQAVASVESRS-----VSTSPSILTAFLKESRAPEHFEQ 355
            + ++E   +   S + QDA    V    S +      ST+  I +  ++ +  P     
Sbjct: 62  TSGRSE---ESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTT 118

Query: 356 EQLRVICHSSGSHTLELSDSTLAPQESSQCPGIMPQ---VHIQAAAAESTAFQRENKLAS 412
             L     S+  H+   S +T     S+   G+  +    H +  +  +TAF      ++
Sbjct: 119 PGLSE--KSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPD----ST 172

Query: 413 LPGGVLKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQIS 472
              G+ + S+ +  S  +  T           P +E +T+    G+  ++L   +   +S
Sbjct: 173 TTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALS 232

Query: 473 ISACSQAETSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDSCGS--------------- 517
                Q  T++      T  + F + TT+    +   ++  S GS               
Sbjct: 233 F---GQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGL 289

Query: 518 ---------------ISKADHSGSLDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTL 562
                           + +  S +  P  +     + P S        S+ T     K+ 
Sbjct: 290 QGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKST 349

Query: 563 LLNPKSQESGGTESAANPTPSPIRKNQESTLEENRQTKT------ATSLSLPSDP-MGDS 615
           + +     SG T S+A+ T S + +   ++  +   T T       T+  L  +P    S
Sbjct: 350 IFHSSPDASGTTPSSAHSTTSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHS 409

Query: 616 SPGSGKKT 623
           S GS + T
Sbjct: 410 SQGSTEAT 417


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 152/718 (21%), Positives = 253/718 (35%), Gaps = 116/718 (16%)

Query: 3    TVPDPLRSAKTSLIAASGKEDDLGEPQAASPRHR--PALL---------CKNANGFSGAP 51
            T+P    S+K      S KE     P AA+P H+  PA+            +  G   +P
Sbjct: 1348 TLPATTPSSKGGPTTPSSKEGPT--PPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSP 1405

Query: 52   AEPDLSPRAA-AEALMQVCEHETTQPDMSSPGVFN-EVQKAPATF---------NSPGNP 100
            A   LSP+ A A  + +      ++ D++ P V    ++KAPAT          +S G+P
Sbjct: 1406 AVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDP 1465

Query: 101  QLPGSSQPAASAPSSAAGRDLIHTPLTMPANQHTCQSIPGDQPNAITSSMPEDSLMRSQR 160
             LP  + P+   P               PA +    S    +  A  + M   +L     
Sbjct: 1466 TLPAVTPPSPKEP---------------PAPKQVATSSSPKKAPATPAPMGAPTLPAVIP 1510

Query: 161  TSNREQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGTVQTPVTAARVVSHSSSPVGGPE 220
            +S +E P  P        SS +D +     +P     + +TP T A   +     +  P 
Sbjct: 1511 SSPKEVPATP--------SSRRDPI-----APTATLLSKKTPATLAPKEALIPPAMTVPS 1557

Query: 221  GERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTS----------VTPQPTPL 270
             ++  AI   +     P ++E+    +  P+VT S  +G  S           +P P   
Sbjct: 1558 PKKTPAIPTPKEAPATPSSKEA----SSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEA 1613

Query: 271  TSEPSACPPGPEKVP-LPAQRQMSRFKEASTMTNQAESEIKEVPSRAWQDAEVQAVASVE 329
             + P+  PP PEK P  PA       K   T      S +K+ P+         + ASV 
Sbjct: 1614 PTPPAVTPPSPEKGPATPAP------KGTPTSPPVTPSSLKDSPT---------SPASVT 1658

Query: 330  SRSVSTSPSILTAFLKESRAPEHFEQEQLRVICHSSGSHTLELSDSTLAPQESSQCPGIM 389
             +  +T P   +  L   + P   ++  +     S+   T          + S+  P I 
Sbjct: 1659 CKMGATVPQ-ASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPIC 1717

Query: 390  PQVHIQAAAAESTAFQRENKLASLPGGVLKTSSINLVSSNAQHTCKEDGRLA-----GMT 444
            P    +  +    +      L  LP  V K SS      +A H+ K  G LA       T
Sbjct: 1718 PDPSAKNGSKGPLSTVAPAPL--LP--VQKDSSKTAKGKDASHSPK--GPLAPPESKAST 1771

Query: 445  PVREESTAKKLAGTNSSSLKATAIDQISISACSQAETSYGLGKFETRPSEFAEKTTNGHK 504
            P+   +  K L    S+S+ A     +S+        +    K +  PS           
Sbjct: 1772 PLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLP-PKQQFLPS----------- 1819

Query: 505  TDPDCKLSDSCGSISKADHSGSLDPTNKGDAREKKPASPQVVK--EKESTGTDTSDAKTL 562
              P   L      ++ AD    L            P    +V     +S G         
Sbjct: 1820 -SPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAK 1878

Query: 563  LLNPKSQESGGTESAANPTPSPIRKNQESTLEENRQTKTATSLSLPSDPMGDSSPG-SGK 621
                K+ +  GTES ++ +  P  + Q+ST    +Q + A +  +  +P+  +    S K
Sbjct: 1879 QPVTKNNKGSGTESDSDES-VPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEK 1937

Query: 622  KTPSRSVKASPRRPSRVSEFLKEQKLNVTAAAAQVGLTPGDKKKQLGADSKLQLKQSK 679
            K      K   R+ + V+     +  N+        +T  D  K   +D+ +   ++K
Sbjct: 1938 KARKAMSKLGLRQVTGVTRVTIRKSKNILFV-----ITKPDVYKSPASDTYIVFGEAK 1990



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 51/207 (24%), Positives = 72/207 (34%), Gaps = 7/207 (3%)

Query: 84   FNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMPANQHTCQSIPGDQP 143
            F   + +PAT +SP  P   G+  P+A  P S  G  L   P   P         P + P
Sbjct: 843  FQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTL--PPKETPTPSVVNLPFPKEGP 900

Query: 144  -NAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGTVQTP 202
                    P  S+  S     R  P     P       +    +   PSP+    T    
Sbjct: 901  ATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPK 960

Query: 203  VTAARVVSHSSSPVGGPEGER-QGAICDSEMRSCKPLTRESGCSEN---KQPSVTASGPQ 258
                   +   SP GGP     +GA          P    +  S       P+VT   P+
Sbjct: 961  WAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK 1020

Query: 259  GTTSVTPQPTPLTSEPSACPPGPEKVP 285
            G+ + TP P   ++ P+A PP P+  P
Sbjct: 1021 GSPAATPFPKGASTPPAATPPSPKGSP 1047



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 71/290 (24%), Positives = 113/290 (38%), Gaps = 39/290 (13%)

Query: 91   PATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMPANQ---HTCQSIPGDQPNAIT 147
            P+   SPG P   G+  P A  P S  G   +  P T P+++    T  S  G  P A T
Sbjct: 1318 PSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTL--PATTPSSKGGPTTPSSKEGPTPPAAT 1375

Query: 148  SSM---PEDSLMRSQRTSNREQPE-KPSCPVGGVLSSSK------DQVSCEFPSPETIQG 197
             S    P  +    +R      P+  P+ P    LS  K       +     PS   +  
Sbjct: 1376 PSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTP 1435

Query: 198  TVQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQPS--VTAS 255
               TPV+  +  + +S+P GGP      A   S+     P        E   P    T+S
Sbjct: 1436 PAVTPVSLKKAPA-TSAPKGGP------ATPSSKGDPTLPAVTPPSPKEPPAPKQVATSS 1488

Query: 256  GPQGTTSVTPQPTPLTSEPSACPPGPEKVP-LPAQRQMSRFKEASTMTNQAESEI--KE- 311
             P+     TP P    + P+  P  P++VP  P+ R+      A+ ++ +  + +  KE 
Sbjct: 1489 SPK-KAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEA 1547

Query: 312  -------VPSRAWQDA---EVQAVASVESRSVSTSPSILTAFLKESRAPE 351
                   VPS     A     +A A+  S+  S+ P++  +  K + +P+
Sbjct: 1548 LIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPK 1597



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 47/204 (23%), Positives = 70/204 (34%), Gaps = 22/204 (10%)

Query: 91   PATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMPANQHTCQSIPGDQPNAITSSM 150
            P+    P  P L G+  P A+ P S  G     +P   P             P A T   
Sbjct: 1065 PSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAP------------MPPAATPPS 1112

Query: 151  PEDSLMRSQRTSNREQPEK-PSCPVGGVLSSS-KDQVSCEFPSPETIQGTVQTPVTAARV 208
            P+  L           P   P  P GG+ +   K   +    +P + +G + TP      
Sbjct: 1113 PKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAP 1172

Query: 209  VSHSSSPVGGPEG----ERQGAICDSEMRSCKP---LTRESGCSENKQPSVTASGPQGTT 261
             + +++P     G      +GA          P   L   S       P+ T   P+G  
Sbjct: 1173 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGL 1232

Query: 262  SVTPQPTPLTSEPSACPPGPEKVP 285
            + TP P    + P+A PP P+  P
Sbjct: 1233 A-TPSPKGAPTTPAATPPSPKGGP 1255



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 10/57 (17%)

Query: 257 PQGTTSVTPQPTPLT----------SEPSACPPGPEKVPLPAQRQMSRFKEASTMTN 303
           PQ  T+V P  + L+          + P  C P P++ PL A  Q S F   ST+ +
Sbjct: 19  PQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIAS 75


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 140/718 (19%), Positives = 251/718 (34%), Gaps = 139/718 (19%)

Query: 1    MGTVPDPLRSAKTSLIAASGKEDDLGEPQAASPRHRPA-----LLCKNANGFSGAPAEPD 55
            +   PD ++S KT+LI+   K+     P + +    P+     L+       S    +  
Sbjct: 4417 LAVTPDFMQSEKTTLISKGPKDVSWTSPPSVAETSYPSSLTPFLVTTIPPATSTLQGQHT 4476

Query: 56   LSPRAAAEALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSPGN---------------- 99
             SP +A   L       T   + S   V N    +P   N+P N                
Sbjct: 4477 SSPVSATSVLTSGLVKTTDMLNTSMEPVTN----SPQNLNNPSNEILATLAATTDIETIH 4532

Query: 100  --------------------PQLPGSSQPAAS----APSSAAGRDLIHTPLTMPANQHTC 135
                                  LP SS+P+ +     P+S+ G  L    +++P ++ T 
Sbjct: 4533 PSINKAVTNMGTASSAHVLHSTLPVSSEPSTATSPMVPASSMGDAL--ASISIPGSETT- 4589

Query: 136  QSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQV---------- 185
              I G+  +++T+   E+S ++   ++        +  VG +  ++K +V          
Sbjct: 4590 -DIEGEPTSSLTAGRKENSTLQEMNSTTESNIILSNVSVGAITEATKMEVPSFDATFIPT 4648

Query: 186  ---SCEFPSPETIQGTVQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRES 242
               S +FP   ++  +  +      + +H ++   G  G            S  PL  ++
Sbjct: 4649 PAQSTKFPDIFSVASSRLSNSPPMTISTHMTTTQTGSSG----------ATSKIPLALDT 4698

Query: 243  GCSENK--QPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEAST 300
               E     PSV   G   +   T     +       PP  +              EAS+
Sbjct: 4699 STLETSAGTPSVVTEGFAHSKITTAMNNDVKDVSQTNPPFQD--------------EASS 4744

Query: 301  MTNQAESEIKEVPSRAWQDAEVQAVAS-VESRSVSTSPSILTAFLKESRAPEHFEQEQLR 359
             ++QA   +  +PS      +  + +S V   SV TS  + TA   ++          L 
Sbjct: 4745 PSSQAPVLVTTLPSSVAFTPQWHSTSSPVSMSSVLTSSLVKTAGKVDT---------SLE 4795

Query: 360  VICHSSGSHTLELSDSTLAPQESSQCPGIMPQVH--IQAAAAESTAFQRENKLASLPGGV 417
             +  S  S +  L D ++    ++      P ++  +       +AF+  + +++ P   
Sbjct: 4796 TVTSSPQSMSNTLDDISVTSAATTDIETTHPSINTVVTNVGTTGSAFESHSTVSAYP--- 4852

Query: 418  LKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNS--SSLKATAIDQISISA 475
                   + S N   +  ED  ++   P   ++T  +   T+S    L+ T+I Q   S+
Sbjct: 4853 ---EPSKVTSPNVTTSTMEDTTISRSIPKSSKTTRTETETTSSLTPKLRETSISQEITSS 4909

Query: 476  CSQAETSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSG-SLDPTNKGD 534
               +   Y          E    TT   +TD     S S  S    D S  SLD + + +
Sbjct: 4910 TETSTVPY---------KELTGATTEVSRTD---VTSSSSTSFPGPDQSTVSLDISTETN 4957

Query: 535  AREKKPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQESTLE 594
             R     SP + +  E T T  +       +  + +   T   +N TP   +    S + 
Sbjct: 4958 TR--LSTSPIMTESAEITITTQTGP-----HGATSQDTFTMDPSNTTP---QAGIHSAMT 5007

Query: 595  ENRQTKTATSL--SLPSDPMGDSSPGSGKKTPSRSVKASP--RRPSRVSEFLKEQKLN 648
                    T+L   +P D    S P   K +   S  +SP    PS +S  L E KL+
Sbjct: 5008 HGFSQLDVTTLMSRIPQDVSWTSPPSVDKTSSPSSFLSSPAMTTPSLISSTLPEDKLS 5065



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 108/540 (20%), Positives = 191/540 (35%), Gaps = 38/540 (7%)

Query: 100  PQLPGSSQPAASAPSSAAGRDLIHTPLTMPANQHTCQSIPGDQPNAITSSMPEDSLMRSQ 159
            P LP  S+  +   +S+  +D++ T  T+PA+    + I  +  + +T +  E S  +  
Sbjct: 8957 PGLPEPSKVTSPVVTSSTIKDIVST--TIPASSEITR-IEMESTSTLTPTPRETSTSQEI 9013

Query: 160  RTSNREQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGTVQTPVTAARVVSHSSSPVGGP 219
             ++ +             +  S  QV      P   Q T+   ++   +   S+SP+   
Sbjct: 9014 HSATKPSTVPYKALTSATIEDSMTQVMSSSRGPSPDQSTMSQDISTEVITRLSTSPIKTE 9073

Query: 220  EGERQ--------GAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTPLT 271
              E          GA     +      T  SG         + S      S TP   P  
Sbjct: 9074 STEMTITTQTGSPGATSRGTLTLDTSTTFMSGTHSTASQGFSHSQMTALMSRTPGDVPWL 9133

Query: 272  SEPSACPPGPEKVPLPAQRQMSRFKEASTMTNQAESEIKEVPSRAWQD-AEVQAVASVES 330
            S PS          L +    S    +ST+ +   S    V S       +   +    S
Sbjct: 9134 SHPSVEEASSASFSLSSPVMTSSSPVSSTLPDSIHSSSLPVTSLLTSGLVKTTELLGTSS 9193

Query: 331  RSVSTSPSILTAFLKESRAPEHF--EQEQLRVICHSSGSHTLELSDSTLAPQESSQCPGI 388
               ++SP  L++   E  A      + E+L +    +  +T E   S LA   +++    
Sbjct: 9194 EPETSSPPNLSSTSAEILAITEVTTDTEKLEMTNVVTSGYTHESPSSVLADSVTTKATSS 9253

Query: 389  MPQVH---------IQAAAAESTAFQRENKLASLPGGVLKTSSINLVSSNAQHTCKEDGR 439
            M   +            A ++++  Q ++KL+  PG  L  +SI+  +S+A     E   
Sbjct: 9254 MGITYPTGDTNVLTSTPAFSDTSRIQTKSKLSLTPG--LMETSISEETSSA----TEKST 9307

Query: 440  LAGMTPVREESTAKKLAGTNSSSLKATAIDQISISACSQAETSYGLGKFETRPSEFAEKT 499
            +    P    +   +    +SS        Q ++S+ +  ET   +    TR        
Sbjct: 9308 VLSSVPTGATTEVSRTEAISSSRTSIPGPAQSTMSSDTSMETITRISTPLTRKESTDMAI 9367

Query: 500  TNGHKTDPDCKLSDSCGSISKADHSGSLDPTNKGDAREKKPASPQVVKEKESTG-TDTSD 558
            T   KT P    S   G+ +    S +  P       ++ P S  VV    S G  D S 
Sbjct: 9368 T--PKTGPSGATSQ--GTFTLDSSSTASWPGTHSATTQRFPQS--VVTTPMSRGPEDVSW 9421

Query: 559  AKTLLLNPKSQESGGTESAANPTPSPIRKNQESTLEENRQTKTA--TSLSLPSDPMGDSS 616
               L +   S  S    S++  +PSP+      +   +    T+  TS+ + +  M D+S
Sbjct: 9422 PSPLSVEKNSPPSSLVSSSSVTSPSPLYSTPSGSSHSSPVPVTSLFTSIMMKATDMLDAS 9481



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 153/778 (19%), Positives = 273/778 (35%), Gaps = 112/778 (14%)

Query: 77    DMSSPGVFN-EVQKAPATFNSPGNPQLPGS--SQPAASAPSSAAGRDLIHTPLTMPANQH 133
             D+S P   + E    P++  S  +   P    S P+ S+ SS      + T + M A   
Sbjct: 9418  DVSWPSPLSVEKNSPPSSLVSSSSVTSPSPLYSTPSGSSHSSPVPVTSLFTSIMMKATDM 9477

Query: 134   TCQSIPGDQPNAITSSMPED-SLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEFPSP 192
                S+  +  +A   ++  D SL  S+ T+  E            + ++         SP
Sbjct: 9478  LDASLEPETTSAPNMNITSDESLAASKATTETEAIHVFENTAASHVETTSATEELYSSSP 9537

Query: 193   ETIQGT-VQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQPS 251
                + T V +PV  +  +  +      P       I    M S  P  RE+  S++    
Sbjct: 9538  GFSEPTKVISPVVTSSSIRDNMVSTTMPGSSGITRIEIESMSSLTPGLRETRTSQD---- 9593

Query: 252   VTASGPQGTT--SVTPQPTPLTSEPSACPPGPEKVPLPAQRQMS---------RFKEAST 300
             +T+S    T    +    TP  S     P     +P PAQ  MS         R   +  
Sbjct: 9594  ITSSTETSTVLYKMPSGATPEVSRTEVMPSSRTSIPGPAQSTMSLDISDEVVTRLSTSPI 9653

Query: 301   MTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKE-------SRAPEHF 353
             MT  AE  I      +   ++V          +S + S ++  L         SR PE  
Sbjct: 9654  MTESAEITITTQTGYSLATSQVTLPLGTSMTFLSGTHSTMSQGLSHSEMTNLMSRGPESL 9713

Query: 354   EQEQLRVI--CHSSGSHT---------------LELSDSTLAPQESSQCPGIMPQVHIQA 396
                  R +    SS S T               L+ S S+  P  S   PG++    +  
Sbjct: 9714  SWTSPRFVETTRSSSSLTSLPLTTSLSPVSSTLLDSSPSSPLPVTSLILPGLVKTTEVLD 9773

Query: 397   AAAESTAFQRENKLASLPGGVLKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLA 456
              ++E        K +S P   L ++S+ + +++   T  E    +  T V +  T+  + 
Sbjct: 9774  TSSEP-------KTSSSPN--LSSTSVEIPATSEIMTDTEKIHPSSNTAVAKVRTSSSVH 9824

Query: 457   GTNSSSLKATAIDQISISACSQAETSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDSCG 516
              ++SS L A +   I+I +            F + P+ F+E  T    T+P   L+    
Sbjct: 9825  ESHSSVL-ADSETTITIPSMGITSAVDDTTVFTSNPA-FSE--TRRIPTEPTFSLTPGFR 9880

Query: 517   SISKADHSGSLDPTNKG-------------------------DAREKKPASPQVVKE--- 548
               S ++ + S+  T+                              ++   SP ++ E   
Sbjct: 9881  ETSTSEETTSITETSAVLYGVPTSATTEVSMTEIMSSNRIHIPDSDQSTMSPDIITEVIT 9940

Query: 549   KESTGTDTSDAKTLLLNPKSQESGGTESAA---NPTPSPIRKNQESTLEENRQTKTATSL 605
             + S+ +  S++  + +  +    G T  +      T +P+ +   +       ++  T +
Sbjct: 9941  RLSSSSMMSESTQMTITTQKSSPGATAQSTLTLATTTAPLARTHSTVPPRFLHSEMTTLM 10000

Query: 606   S-LPSDPMGDSSPGSGKKTPSRS-----VKASPRRPSRVSEFLKEQKLNVTAAAAQVGLT 659
             S  P +P   SS    K + S S     V  SP   S + + +     +VT+      LT
Sbjct: 10001 SRSPENPSWKSSLFVEKTSSSSSLLSLPVTTSPSVSSTLPQSIPSSSFSVTSL-----LT 10055

Query: 660   PG-----DKKKQLGADSKLQLKQSKRVRDVVWDEQGMTWEVY-GASLDAESLGIAIQNH- 712
             PG     D   + G      L  +        +    T +++  +S+   ++G     H 
Sbjct: 10056 PGMVKTTDTSTEPGTSLSPNLSGTSVEILAASEVTTDTEKIHPSSSMAVTNVGTTSSGHE 10115

Query: 713   LQRQIREHEKLIK------TQNSQTRRSISSDTSSNKKLRGRQHSVFQSMLQNFRRPN 764
             L   +  H +  K      T +S    SIS+   +N +  G +   F  +   FR+ N
Sbjct: 10116 LYSSVSIHSEPSKATYPVGTPSSMAETSISTSMPANFETTGFEAEPFSHLTSGFRKTN 10173



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 133/624 (21%), Positives = 213/624 (34%), Gaps = 104/624 (16%)

Query: 48   SGAPAEPDLSPRAAAEALMQVCEHE----TTQPDMSSPGVFNEVQKAPATFNSPGNPQLP 103
            SGA  E   +P    E+L+ V E      T++  ++   +F+ V   P+ F S G   L 
Sbjct: 2583 SGANWETSATP----ESLLVVTETSDTTLTSKILVTDTILFSTVSTPPSKFPSTGT--LS 2636

Query: 104  GSSQPA-----------ASAPSSAAGRDLIHTPLTMPANQHTCQSIPGDQPNAITSSMPE 152
            G+S P            A+ P+S+       TPL   A+     S+       +T S   
Sbjct: 2637 GASFPTLLPDTPAIPLTATEPTSSLATSFDSTPLVTIASD----SLGTVPETTLTMSETS 2692

Query: 153  DSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGTVQTPVTAARVVSHS 212
            +      +T +      P   + GV  S     S    SP  I     T    +  V+ S
Sbjct: 2693 NGDALVLKTVSNPDRSIPGITIQGVTESPLHPSST---SPSKIVAPRNTTYEGSITVALS 2749

Query: 213  SSPVG---------GPEGERQGAICDS----EMRSCKPLTRESGCSENKQPSVTASGPQG 259
            + P G           E     A+ DS    E  S  PLT  S    +    + +     
Sbjct: 2750 TLPAGTTGSLVFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSG-GIRSGSTHS 2808

Query: 260  TTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEAST--MTNQAESEIKEVPSRAW 317
            T + T    PLT  P                +++   E +T  +T    +  K +P +  
Sbjct: 2809 TGTKTFSSLPLTMNPG---------------EVTAMSEITTNRLTATQSTAPKGIPVKP- 2852

Query: 318  QDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRVICHSSGSHTLELSDSTL 377
              AE   +  V   S S+SPS   AF   + AP  +   Q  +    S   +L+   ++L
Sbjct: 2853 TSAESGLLTPV---SASSSPS--KAFASLTTAPPTWGIPQSTLTFEFSEVPSLDTKSASL 2907

Query: 378  APQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVLKTSSINLVSSNAQHTCKED 437
                  Q    +P      A++  +    +N     P   + TS+  + +S+ Q T    
Sbjct: 2908 PTP--GQSLNTIPDSDASTASSSLSKSPEKN-----PRARMMTSTKAISASSFQST---- 2956

Query: 438  GRLAGMTPVREESTAKKLAG---------TNSSSLKATAIDQISISACSQAETSYGLGKF 488
                G T   E S +  +AG         T      + ++     S  S A TS  L   
Sbjct: 2957 ----GFTETPEGSASPSMAGHEPRVPTSGTGDPRYASESMSYPDPSKASSAMTSTSLASK 3012

Query: 489  ETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSGSLDPTNKGDAREKKPASPQVVKE 548
             T      +   +G  + P         S+S    +  L PT     +      P + ++
Sbjct: 3013 LTTLFSTGQAARSGSSSSPI--------SLSTEKETSFLSPTASTSRKTSLFLGPSMARQ 3064

Query: 549  KESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQESTLEENRQTKTATSLSLP 608
                    + A TL  +P S     T + +   P  +  +Q    EE    +T T    P
Sbjct: 3065 PNILVHLQTSALTL--SPTS-----TLNMSQEEPPELTSSQTIAEEEGTTAETQTLTFTP 3117

Query: 609  SDPMGDSSPGSGKKTPSRSVKASP 632
            S+      P S    P+   K+SP
Sbjct: 3118 SETPTSLLPVSSPTEPTARRKSSP 3141



 Score = 37.7 bits (86), Expect = 0.041
 Identities = 118/612 (19%), Positives = 219/612 (35%), Gaps = 89/612 (14%)

Query: 106  SQPAASAPSSAAGRDLIHTPLTMPANQHTCQSIPGDQPNAI-TSSMPEDSLMRSQRTSNR 164
            S PA ++P   +   L H P +         S P    + + TS+ P  S   S  T++ 
Sbjct: 7692 SLPAVTSPHPVSTTFLAHIPPSPLPVTSLLTSGPATTTDILGTSTEPGTSSSSSLSTTSH 7751

Query: 165  EQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGTVQTPVTAARVVSHSSSPVGGPEGERQ 224
            E+           L++ KD    E   P T  G      T++   S SS           
Sbjct: 7752 ER-----------LTTYKDTAHTEAVHPSTNTGGTNVATTSSGYKSQSSVLADSSPMCTT 7800

Query: 225  GAICDSEMRSCKPLTRESGCSENKQPSVT------ASGPQGTTSVTPQPTPLTSEPSACP 278
              + D+ + +  P   E+   + +  S        +SG +GT+S T   T L+  P+   
Sbjct: 7801 STMGDTSVLTSTPAFLETRRIQTELASSLTPGLRESSGSEGTSSGTKMSTVLSKVPTGAT 7860

Query: 279  PGPEK-----VPLPAQ---------RQMSRFKEASTMTNQAESEIKEVPSRAWQDAEVQA 324
                K     +P PAQ         R +S F  +  MT  AE  +    S     A  Q 
Sbjct: 7861 TEISKEDVTSIPGPAQSTISPDISTRTVSWFSTSPVMTESAEITMNTHTSPL--GATTQG 7918

Query: 325  VASVESRSVS----TSPSILTAFLKES------RAPEHFEQEQLRVICHSSGSHTLELSD 374
             +++++ S +    T  +I   F          R PE        ++  +  S +L  S 
Sbjct: 7919 TSTLDTSSTTSLTMTHSTISQGFSHSQMSTLMRRGPEDVSWMSPPLLEKTRPSFSLMSSP 7978

Query: 375  STLAPQ----------ESSQCP-------GIMPQVHIQAAAAESTAFQRENKLASLPGGV 417
            +T +P            SS  P       G+     +   ++E       N L+S    +
Sbjct: 7979 ATTSPSPVSSTLPESISSSPLPVTSLLTSGLAKTTDMLHKSSEPVTNSPAN-LSSTSVEI 8037

Query: 418  LKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISACS 477
            L TS +   +     +        G +    EST+  LA + +S + +  +   ++   S
Sbjct: 8038 LATSEVTTDTEKTHPSSNRTVTDVGTSSSGHESTSFVLADSQTSKVTSPMVITSTMEDTS 8097

Query: 478  QAETSYGL---GKFETRPSEF----AEKTTNGHKTDPDCKLS--------DSCGSISKAD 522
             + ++ G     + +T P+        KT++   T    ++S         +   +S+ +
Sbjct: 8098 VSTSTPGFFETSRIQTEPTSSLTLGLRKTSSSEGTSLATEMSTVLSGVPTGATAEVSRTE 8157

Query: 523  HSGSLDPTNKGDAREKKPASPQVVKE---KESTGTDTSDAKTLLLNPKSQESGGTESAA- 578
             + S   +  G A  +   SP+   E   +  T +  +++  +++  ++   G T  +  
Sbjct: 8158 VTSSSRTSISGFA--QLTVSPETSTETITRLPTSSIMTESAEMMIKTQTDPPGSTPESTH 8215

Query: 579  ----NPTPSPIRKNQESTLEENRQTKTATSLSLPSDPMGDSSPGSGKKTPSRSVKASP-- 632
                + TP+ +  +   T   +    T      P D +  S     + + + S+ + P  
Sbjct: 8216 TVDISTTPNWVETHSTVTQRFSHSEMTTLVSRSPGDMLWPSQSSVEETSSASSLLSLPAT 8275

Query: 633  RRPSRVSEFLKE 644
              PS VS  L E
Sbjct: 8276 TSPSPVSSTLVE 8287



 Score = 37.0 bits (84), Expect = 0.070
 Identities = 101/485 (20%), Positives = 174/485 (35%), Gaps = 61/485 (12%)

Query: 170  PSCPVG-GVLSSSKDQVSCEFPSP--ETIQGT--VQTPVTAARVVSHSSSPVGGPEGERQ 224
            PS P+  G+  SS   +      P   T QGT  + TP T++R  +HS +    P  E  
Sbjct: 6719 PSLPISLGITESSNMTIITRTGPPLGSTSQGTFTLDTPTTSSRAGTHSMATQEFPHSEMT 6778

Query: 225  GAI-CDSEMRS--CKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGP 281
              +  D E+ S    P   ++  S +  PS   + P  ++++   P  + + PS      
Sbjct: 6779 TVMNKDPEILSWTIPPSIEKTSFSSSLMPSPAMTSPPVSSTL---PKTIHTTPS------ 6829

Query: 282  EKVPLPAQRQMSRFKEASTMTNQAESEIKEVPSRAWQDAEV----QAVASVESRSVSTSP 337
               P+ +    S      T+    E      P+ +    E+    +   ++E+   STS 
Sbjct: 6830 ---PMTSLLTPSLVMTTDTLGTSPEPTTSSPPNLSSTSHEILTTDEDTTAIEAMHPSTST 6886

Query: 338  SILTAFLKESRAPEHFEQEQLRVICHSSGSHTLELSDST--LAPQESSQCPGIMPQVHIQ 395
            +        S               H S S  L  S+ T   AP +++   G        
Sbjct: 6887 AATNVETTSSG--------------HGSQSSVLADSEKTKATAPMDTTSTMGHTTVSTSM 6932

Query: 396  AAAAESTAFQRENKLASLPGGVLKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKL 455
            + ++E+T  +RE+  +  PG  L+ +SI+  +S +  T      +   T      T    
Sbjct: 6933 SVSSETTKIKRESTYSLTPG--LRETSISQNASFSTDTSIVLSEVPTGTTAEVSRTEVTS 6990

Query: 456  AGTNS--SSLKATAIDQISISACSQAETSYGLGKFETRPSEFAEKTTNG--HKTDPDCKL 511
            +G  S     ++T + +IS    ++   S  +    T  +E    T  G    T  D   
Sbjct: 6991 SGRTSIPGPSQSTVLPEISTRTMTRLFASPTM----TESAEMTIPTQTGPSGSTSQDTLT 7046

Query: 512  SDSCGSISKADHSGSLDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLLLNPKSQES 571
             D+  + S+A    +L         ++ P S          G  +  +   L NP S  S
Sbjct: 7047 LDTSTTKSQAKTHSTL--------TQRFPHSEMTTLMSRGPGDMSWQSSPSLENPSSLPS 7098

Query: 572  GGTESAANPTPSPIRKNQESTLEEN--RQTKTATSLSLPSDPMGDSSPGSGKKTPSRSVK 629
                  A  +P PI      T+  +    T   TS  + +  M  +SP     +P +   
Sbjct: 7099 -LLSLPATTSPPPISSTLPVTISSSPLPVTSLLTSSPVTTTDMLHTSPELVTSSPPKLSH 7157

Query: 630  ASPRR 634
             S  R
Sbjct: 7158 TSDER 7162



 Score = 36.2 bits (82), Expect = 0.12
 Identities = 112/574 (19%), Positives = 197/574 (34%), Gaps = 64/574 (11%)

Query: 103  PGSSQPAASAPSSAAGRDLIHTPLTMPANQHTCQSIPGDQPNAITSSMPEDSLMRSQRTS 162
            PG++  +A    ++A      TPL       T Q     +   + S  PED+   S  + 
Sbjct: 4100 PGATSLSAPTLDTSATASWTGTPLA------TTQRFTYSEKTTLFSKGPEDTSQPSPPSV 4153

Query: 163  NREQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGTVQTPVTAARVVSHSSSPVGGPEGE 222
                      P+    S S   ++ +  SP +      TP   +  +S +S      +  
Sbjct: 4154 EETSSSSSLVPIHATTSPSNILLTSQGHSPSS------TPPVTSVFLSETSGLGKTTDMS 4207

Query: 223  R----QGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACP 278
            R     G      + S       +  +     ++  S     T++    +  +  P    
Sbjct: 4208 RISLEPGTSLPPNLSSTAGEALSTYEASRDTKAIHHSADTAVTNMEATSSEYSPIPGHTK 4267

Query: 279  PGPEKVPLPAQRQMSRFKEASTMTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSPS 338
            P     PL     M     ++++   +E+   E  S   Q  + ++ + V S +  TS  
Sbjct: 4268 PSKATSPLVTSHIMGDITSSTSVFGSSETTEIETVSSVNQGLQERSTSQVASSATETSTV 4327

Query: 339  ILTAFLKESRAPEHFEQEQLRVICHSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAA 398
            I    +    A  H  + Q      +S S   +   ST    + S  P     +  +++ 
Sbjct: 4328 I--THVSSGDATTHVTKTQATFSSGTSISSPHQFITSTNTFTDVSTNPSTS-LIMTESSG 4384

Query: 399  AESTAFQRENKLASLPGGVLKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGT 458
               T        A+    +L TS++  ++               +TP   +S    L   
Sbjct: 4385 VTITTQTGPTGAATQGPYLLDTSTMPYLTETP----------LAVTPDFMQSEKTTLISK 4434

Query: 459  NSSSLKATAIDQISISACSQAETSY--GLGKFETRPSEFAEKTTNGHKTDPDCKLSD--S 514
                +  T       S  S AETSY   L  F       A  T  G  T      +   +
Sbjct: 4435 GPKDVSWT-------SPPSVAETSYPSSLTPFLVTTIPPATSTLQGQHTSSPVSATSVLT 4487

Query: 515  CGSISKADH-SGSLDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLLLN-PKSQESG 572
             G +   D  + S++P          P++     E  +T   T+D +T+  +  K+  + 
Sbjct: 4488 SGLVKTTDMLNTSMEPVTNSPQNLNNPSN-----EILATLAATTDIETIHPSINKAVTNM 4542

Query: 573  GTESAANPTPSPIRKNQESTLEENRQTKTATSLSLPSDPMGD-----SSPGSG----KKT 623
            GT S+A+           STL  + +  TATS  +P+  MGD     S PGS     +  
Sbjct: 4543 GTASSAHVL--------HSTLPVSSEPSTATSPMVPASSMGDALASISIPGSETTDIEGE 4594

Query: 624  PSRSVKASPRRPSRVSEFLKEQKLNVTAAAAQVG 657
            P+ S+ A  +  S + E     + N+  +   VG
Sbjct: 4595 PTSSLTAGRKENSTLQEMNSTTESNIILSNVSVG 4628



 Score = 33.5 bits (75), Expect = 0.77
 Identities = 130/620 (20%), Positives = 210/620 (33%), Gaps = 111/620 (17%)

Query: 103  PGSSQPAASAPSSAAGRDL------IHTPL-TMPANQHTCQSIPGDQPNAIT--SSMPED 153
            P S   A    +S + R L        TP+ T    Q    S+P     + T  S+  ED
Sbjct: 3645 PSSDASAVKTETSTSERTLSPSDTTASTPISTFSRVQRMSISVPDILSTSWTPSSTEAED 3704

Query: 154  SLMRSQRTSNREQPEKPSCPVGGVLSSSKD--------QVSCEFPSPETIQG-TVQTPVT 204
              +    T +      P+ P+   L  S           +S    +    QG T    +T
Sbjct: 3705 VPVSMVSTDHASTKTDPNTPLSTFLFDSLSTLDWDTGRSLSSATATTSAPQGATTPQELT 3764

Query: 205  AARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVT 264
               ++S ++S +    G    A+  + M     +T       +K+   T++    TTS  
Sbjct: 3765 LETMISPATSQLPFSIGHITSAVTPAAMARSSGVTFSRPDPTSKKAEQTSTQLPTTTSAH 3824

Query: 265  PQPTPLTSEPSA-CPPGPEKVP---LPAQRQMSRFKEASTMTNQAESEIKEVPSRAWQDA 320
            P   P ++  +    P   K P      Q Q +   EA   ++    + K  PS  W   
Sbjct: 3825 PGQVPRSAATTLDVIPHTAKTPDATFQRQGQTALTTEARATSDSWNEKEKSTPSAPWITE 3884

Query: 321  EVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRVICHSSGSHTLELSDSTLAPQ 380
             + +V+    + V++S S+L                            TL   D  L   
Sbjct: 3885 MMNSVSEDTIKEVTSSSSVL---------------------------RTLNTLDINLESG 3917

Query: 381  ESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVLKTSSINLVSSNAQHTCKEDGRL 440
             +S  P      + + A +EST     +K A  P       S N V +    T  E    
Sbjct: 3918 TTSS-PSWKSSPYERIAPSESTT----DKEAIHP-------STNTVETTGWVTSSEH--- 3962

Query: 441  AGMTPVREESTAKKLAG-TNSSSLKATAIDQISISACSQAETSYGLGKFETRPSEFAEKT 499
            A  + +   S + KL     ++S +  AI  +S+S  +  E++    +  T P+ F   T
Sbjct: 3963 ASHSTIPAHSASSKLTSPVVTTSTREQAI--VSMSTTTWPEST----RARTEPNSFL--T 4014

Query: 500  TNGHKTDPDCKLSDSC-GSISKADHSGSLDPTNKGDAREKKPASPQVVKEKESTGTDTSD 558
                   P    S +   SI  +  S ++    + +    K  S   + +   +    S+
Sbjct: 4015 IELRDVSPYMDTSSTTQTSIISSPGSTAITKGPRTEITSSKRISSSFLAQSMRSSDSPSE 4074

Query: 559  AKTLLLN-PKSQESGG---------------------TESAANPTPSPIRKNQESTLEEN 596
            A T L N P   ESGG                     T + A+ T +P+   Q  T  E 
Sbjct: 4075 AITRLSNFPAMTESGGMILAMQTSPPGATSLSAPTLDTSATASWTGTPLATTQRFTYSEK 4134

Query: 597  RQ--TKTATSLSLPSDPMGDSSPGSGKKTPSRSVKA-----------SP-RRPSRVSEFL 642
                +K     S PS P  + +  S    P  +  +           SP   P   S FL
Sbjct: 4135 TTLFSKGPEDTSQPSPPSVEETSSSSSLVPIHATTSPSNILLTSQGHSPSSTPPVTSVFL 4194

Query: 643  KEQK-LNVTAAAAQVGLTPG 661
             E   L  T   +++ L PG
Sbjct: 4195 SETSGLGKTTDMSRISLEPG 4214



 Score = 32.3 bits (72), Expect = 1.7
 Identities = 112/524 (21%), Positives = 191/524 (36%), Gaps = 106/524 (20%)

Query: 143  PNAITSSMPEDSL---MRSQRTSN----------REQPEKPSCP-----VGGVLSSSKDQ 184
            P+ I+S++PED L   M S  TS           R +P   S P        +L++SKD 
Sbjct: 5052 PSLISSTLPEDKLSSPMTSLLTSGLVKITDILRTRLEPVTSSLPNFSSTSDKILATSKDS 5111

Query: 185  VSCE--FPSPETIQGTVQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRES 242
               +  FPS  T     +T V A      S SP          A+ DSE           
Sbjct: 5112 KDTKEIFPSINT----EETNVKANNSGHESHSP----------ALADSETPKA------- 5150

Query: 243  GCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEASTMT 302
              +     + T   P  +TS+   P   +SE +     P     P  R+ S  +E+S  T
Sbjct: 5151 --TTQMVITTTVGDPAPSTSM---PVHGSSETTNIKREPTYFLTPRLRETSTSQESSFPT 5205

Query: 303  NQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAP-EHFEQEQLRVI 361
            + +   + +VP+          +  V S  V++S  I T    +S  P + F  E  RV 
Sbjct: 5206 DTSFL-LSKVPTGT--------ITEVSSTGVNSSSKISTPDHDKSTVPPDTFTGEIPRVF 5256

Query: 362  CHSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVLKTS 421
              S  + + E++ +T                  QA+  ES +       ++LP   L TS
Sbjct: 5257 TSSIKTKSAEMTITT------------------QASPPESASH------STLP---LDTS 5289

Query: 422  SINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISACSQAET 481
            +   +S    H+    G      P  E +T   +   N S +    +++ S  +   +  
Sbjct: 5290 TT--LSQGGTHSTVTQG-----FPYSEVTTLMGMGPGNVSWMTTPPVEETSSVSSLMSSP 5342

Query: 482  SYGLGKFETRPSEFAEKTTNGHKTDP-DCKLSDSCGSISKADHSGSLDPTNKGDAREKKP 540
            +       T PS  +  +     + P       +   ++  D  G+  P +        P
Sbjct: 5343 AM------TSPSPVSSTSPQSIPSSPLPVTALPTSVLVTTTDVLGTTSPES---VTSSPP 5393

Query: 541  ASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQESTLEENRQTK 600
                +  E+ +T  DT+  +  +       S  T      T     K+Q S L ++ +T 
Sbjct: 5394 NLSSITHERPATYKDTAHTEAAM-----HHSTNTAVTNVGTSGSGHKSQSSVLADS-ETS 5447

Query: 601  TATSLSLPSDPMGDSSPGSGKKTPSRSVKASPRRPSRVSEFLKE 644
             AT L   +  +GD+S  +     S++ +      + +S  L+E
Sbjct: 5448 KATPLMSTTSTLGDTSVSTSTPNISQTNQIQTEPTASLSPRLRE 5491



 Score = 31.6 bits (70), Expect = 2.9
 Identities = 63/282 (22%), Positives = 109/282 (38%), Gaps = 33/282 (11%)

Query: 351  EHFEQEQLRVICHSSGSH-TLELSDSTLAPQESS--QCPGIMPQVHIQA-AAAESTAFQR 406
            EH  Q Q  +    S +H T  L D T  P  +S      + P++  Q  +++E+T F +
Sbjct: 1549 EHSTQAQDTLSATMSPTHVTQSLKDQTSIPASASPSHLTEVYPELGTQGRSSSEATTFWK 1608

Query: 407  ENKLASLPGGVLKTSSINLVSSNAQHTCKEDGRLAGMT------PVREESTAKKLAGTNS 460
             +         ++T   N+ S+            +G+T      P+   S A+       
Sbjct: 1609 PS--TDTLSREIETGPTNIQSTPPMDNTTTGSSSSGVTLGIAHLPIGTSSPAETSTNMAL 1666

Query: 461  SSLKATAIDQIS------ISACSQAETSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDS 514
                +TA   ++      +++      S  LG+     S  +E TT G  TD     S  
Sbjct: 1667 ERRSSTATVSMAGTMGLLVTSAPGRSISQSLGRVS---SVLSESTTEG-VTDSSKGSSPR 1722

Query: 515  CGSISKADHSGSLDPTNKGDAR-------EKKPASPQVVKEKESTGTDTSDAKTLLLNPK 567
              +      S SL+P+    ++          P +P V     ST   T +  T++ +  
Sbjct: 1723 LNTQGNTALSSSLEPSYAEGSQMSTSIPLTSSPTTPDVEFIGGSTFW-TKEVTTVMTSDI 1781

Query: 568  SQESGGTESAANPTPSPIRKNQESTLEENRQTKTATSLSLPS 609
            S+ S  TES++    S    + E+T +E  +T    S+ LPS
Sbjct: 1782 SKSSARTESSSATLMSTALGSTENTGKEKLRT---ASMDLPS 1820



 Score = 31.2 bits (69), Expect = 3.8
 Identities = 92/452 (20%), Positives = 155/452 (34%), Gaps = 45/452 (9%)

Query: 180  SSKDQVSCEFPSP-ETIQGTV--QTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCK 236
            S++  ++ E  SP  T +GT+   T  T     +HS++  G    E    +  S      
Sbjct: 8490 SAESAITIETGSPGATSEGTLTLDTSTTTFWSGTHSTASPGFSHSEMTTLM--SRTPGDV 8547

Query: 237  PLTRESGCSENKQPSVTASGPQGTTS--VTPQPTPLTSEPSACPPGPEKVPLPAQRQMSR 294
            P        E    S + S P  T++   +  P  ++S P          P+ A   +  
Sbjct: 8548 PWPSLPSVEEASSVSSSLSSPAMTSTSFFSTLPESISSSPH---------PVTALLTLGP 8598

Query: 295  FKEASTMTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFE 354
             K    +   +E E    P+ +   AE+ A + V        PS  T  +          
Sbjct: 8599 VKTTDMLRTSSEPETSSPPNLSSTSAEILATSEVTKDREKIHPSSNTPVVNVGTV----- 8653

Query: 355  QEQLRVICHSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLP 414
                 +  H S S  L     T  P         +    +  +             +SL 
Sbjct: 8654 -----IYKHLSPSSVLA-DLVTTKPTSPMATTSTLGNTSVSTSTPAFPETMMTQPTSSLT 8707

Query: 415  GGVLKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSS-LKATAIDQIS- 472
             G+ + S+    SS  + +    G   G T     + A  L  T++    ++T   +IS 
Sbjct: 8708 SGLREISTSQETSSATERSASLSGMPTGATTKVSRTEALSLGRTSTPGPAQSTISPEIST 8767

Query: 473  --ISACSQAETSYGLGKFETRPSE-FAEKTTNGHKTDPDCKLSDSCGSISKADH----SG 525
              I+  S   T+ G  +    P    +  ++ G  T      +   G+ S A H    SG
Sbjct: 8768 ETITRISTPLTTTGSAEMTITPKTGHSGASSQGTFTLDTSSRASWPGTHSAATHRSPHSG 8827

Query: 526  SLDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPI 585
               P ++G      P+ P V K    +   +  A T   +P    S  +ES+ +   SP+
Sbjct: 8828 MTTPMSRGPEDVSWPSRPSVEKTSPPSSLVSLSAVT---SPSPLYSTPSESSHS---SPL 8881

Query: 586  RKNQESTLEENRQTKTATSLSLPSDPMGDSSP 617
            R    ++L      KT   L    +P+  S P
Sbjct: 8882 R---VTSLFTPVMMKTTDMLDTSLEPVTTSPP 8910



 Score = 31.2 bits (69), Expect = 3.8
 Identities = 53/241 (21%), Positives = 94/241 (39%), Gaps = 19/241 (7%)

Query: 250   PSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEASTMTNQAESEI 309
             PS+T S    ++S  P PT  T  P    P    +   ++  +S      T+   +  E 
Sbjct: 10851 PSMTTSHGAESSSAVPTPTVSTEVPGVVTP----LVTSSRAVISTTIPILTL---SPGEP 10903

Query: 310   KEVPSRAWQDAEVQAVASVESRSVSTS-PSILTAFLKESRAPEHFEQEQLRVICHSSGSH 368
             +  PS A    E +A +++ + +VS   P ++T+ +  SRA        + ++  S G  
Sbjct: 10904 ETTPSMATSHGE-EASSAIPTPTVSPGVPGVVTSLVTSSRA---VTSTTIPILTFSLGEP 10959

Query: 369   TLELSDSTLAPQES-SQCPGIMPQV--HIQAAAAESTAFQREN--KLASLPGGVLKTSSI 423
                 S +T    E+ S  P ++P+V   + +  A S A        L   PG    T S 
Sbjct: 10960 ETTPSMATSHGTEAGSAVPTVLPEVPGMVTSLVASSRAVTSTTLPTLTLSPGEPETTPS- 11018

Query: 424   NLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISACSQAETSY 483
              + +S+          ++   P    S     +G NS+S+    +    +       TS+
Sbjct: 11019 -MATSHGAEASSTVPTVSPEVPGVVTSLVTSSSGVNSTSIPTLILSPGELETTPSMATSH 11077

Query: 484   G 484
             G
Sbjct: 11078 G 11078


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 673

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 92/416 (22%), Positives = 144/416 (34%), Gaps = 43/416 (10%)

Query: 251 SVTASGPQGTTSVTPQPTPLT-----SEPSACPPGPEKVPLPAQRQMSRFKEASTMTNQ- 304
           S+T + P+ + ++TP    LT     + P+  P       +P+   +++    +++T   
Sbjct: 156 SLTRTPPRASLTMTPSTASLTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTL 215

Query: 305 AESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQLRVICHS 364
           + +     P RA          S    S+S  PS         RA          ++  +
Sbjct: 216 SRASPTGTPPRA------SPTGSPPRASLSMMPSTALLIRTPPRA------SPTGMLSRT 263

Query: 365 SGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVLKTSSIN 424
           S +     +  T  P   S             +   STA        + P G+L  +S+ 
Sbjct: 264 SLTKMDSTASITRTPSRPSTASPTGTPSRASLSMTPSTASLMRMLPRASPTGMLSRTSLT 323

Query: 425 LVSSNAQHTCKEDGRLAGMTPVREESTAKKLA----GTNSSSLKATAIDQISISACSQAE 480
            + S A  +          TP R   T K       GT S +    +    S++  S   
Sbjct: 324 KMDSTASISRTPPRASITRTPSRASPTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTA 383

Query: 481 TSYGLGK--FETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSGSLDPTNKGDAREK 538
           +  G       T     A  T    +  P   LS +  SI+K D + S   T    +   
Sbjct: 384 SPTGTPPRASPTGTPSTASLTRKPPRASPTGMLSRT--SITKMDSTASPTRTPPRASPTG 441

Query: 539 KP--ASPQVVKEKES-TGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKN------- 588
            P  ASP     + S TGT ++ + T   +P +    G+ S A+PT SP R +       
Sbjct: 442 TPPRASPTGTPSRASPTGTQSTASPTG--SPSTASPTGSPSTASPTGSPSRASLTRTPSR 499

Query: 589 -----QESTLEENRQTKTATSLSLPSDPMGDSSPGSGKKTPSRSVKASPRRPSRVS 639
                 EST    R    A+    PS      SP +     S S  A  R PSR S
Sbjct: 500 ASLTKMESTASITRTPSRASPTWTPSTASPTGSPSTALAMGSPSRAALTRTPSRAS 555



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 94/458 (20%), Positives = 169/458 (36%), Gaps = 41/458 (8%)

Query: 230 SEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQ 289
           + M+S   LTR    +  K+    AS  +     +    P T+  +  P        P++
Sbjct: 77  TRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMRRPSTASLTRSPSRASLTTTPSR 136

Query: 290 RQMSRFKE-ASTMTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESR 348
             +S     A+ +T  + + +   P RA       + AS+       SP+ + +    + 
Sbjct: 137 ASLSMTPSTAAALTMPSRASLTRTPPRA-SLTMTPSTASLTRTPPRASPTGMPSRTSPTG 195

Query: 349 APEHFEQEQLRVICHSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQREN 408
            P        ++   +S + TL  +  T  P  +S   G  P+  +  +   STA     
Sbjct: 196 MPS--TASLTKMDSTASITRTLSRASPTGTPPRASPT-GSPPRASL--SMMPSTALLIRT 250

Query: 409 KLASLPGGVLKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSL----- 463
              + P G+L  +S+  + S A  T +   R +  +P    S A      +++SL     
Sbjct: 251 PPRASPTGMLSRTSLTKMDSTASIT-RTPSRPSTASPTGTPSRASLSMTPSTASLMRMLP 309

Query: 464 KATAIDQISISACSQAETSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDSC--GSISKA 521
           +A+    +S ++ ++ +++  + +   R    A  T    +  P  K S +   G+ S+A
Sbjct: 310 RASPTGMLSRTSLTKMDSTASISRTPPR----ASITRTPSRASPTGKPSTASPTGTPSRA 365

Query: 522 DHSGSLDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLLLNPKSQESG--------G 573
             +GS  P+          ASP     + S     S A      P++  +G         
Sbjct: 366 SPTGS--PSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKPPRASPTGMLSRTSITK 423

Query: 574 TESAANPTPSPIRKNQESTLEENRQT------------KTATSLSLPSDPMGDSSPGSGK 621
            +S A+PT +P R +   T      T             TA+    PS      SP +  
Sbjct: 424 MDSTASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQSTASPTGSPSTASPTGSPSTAS 483

Query: 622 KTPSRSVKASPRRPSRVSEFLKEQKLNVTAAAAQVGLT 659
            T S S  +  R PSR S    E   ++T   ++   T
Sbjct: 484 PTGSPSRASLTRTPSRASLTKMESTASITRTPSRASPT 521



 Score = 38.9 bits (89), Expect = 0.018
 Identities = 128/653 (19%), Positives = 214/653 (32%), Gaps = 59/653 (9%)

Query: 7   PLRSAKTSLIAASGKEDDL-GEPQAASPRHRPALLCKNANGFSGAPAEPDL--------- 56
           P R+  T+ +  +     L G P  AS    P+         +G P    L         
Sbjct: 13  PTRTPSTASLTGTPSRASLTGTPSTASLMGTPSRA-----SLTGTPPRASLKGTTSMASL 67

Query: 57  --SPRAAAEALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPS 114
             SP  A+   MQ     T  P M+S  +     +A  T   P    +   S  + +   
Sbjct: 68  MVSPSRASLTRMQSSSLLTRTPSMAS--LKRMPPRASRTRTLPRASLMRRPSTASLTRSP 125

Query: 115 SAAGRDLIHTPLTMPANQHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPV 174
           S A      +  ++     T  ++      ++T + P  SL  +  T++  +    + P 
Sbjct: 126 SRASLTTTPSRASLSMTPSTAAALTMPSRASLTRTPPRASLTMTPSTASLTRTPPRASPT 185

Query: 175 GGVLSSSKDQVSCEFPSPETIQGTVQTPVTAARVVSHSSSPVGGPEGERQGA---ICDSE 231
           G    +S   +     S   +  T     T +R     + P   P G    A   +  S 
Sbjct: 186 GMPSRTSPTGMPST-ASLTKMDSTASITRTLSRASPTGTPPRASPTGSPPRASLSMMPST 244

Query: 232 MRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPT-PLTSEPSACPPGPEKVPLPAQR 290
               +   R S      + S+T      T S+T  P+ P T+ P+  P        P+  
Sbjct: 245 ALLIRTPPRASPTGMLSRTSLTKM--DSTASITRTPSRPSTASPTGTPSRASLSMTPSTA 302

Query: 291 QMSRFKEASTMTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAP 350
            + R    ++ T           S    D+      +    S++ +PS  +   K S A 
Sbjct: 303 SLMRMLPRASPTGMLSRT-----SLTKMDSTASISRTPPRASITRTPSRASPTGKPSTAS 357

Query: 351 EHFEQEQLRVICHSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKL 410
                        S  S T   S ++L    S+  P   P          + +  R+   
Sbjct: 358 PTGTP--------SRASPTGSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKPPR 409

Query: 411 ASLPGGVLKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAK--KLAGTNSSSLKATAI 468
           AS P G+L  +SI  + S A  T          TP R   T    + + T + S  +   
Sbjct: 410 AS-PTGMLSRTSITKMDSTASPT---------RTPPRASPTGTPPRASPTGTPSRASPTG 459

Query: 469 DQISISACSQAETSYGLGKFETRPSEFAEKTTNGHKTDPDCKLS--DSCGSISKADHSGS 526
            Q + S      T+   G   T     +    +  +T     L+  +S  SI++     S
Sbjct: 460 TQSTASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSRASLTKMESTASITRTPSRAS 519

Query: 527 LDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIR 586
              T    +    P++   +          + ++  L    S+ S  T S A+ T +P  
Sbjct: 520 PTWTPSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRASLTRTP-- 577

Query: 587 KNQESTLEENRQTKTATSLSLPSDPMGDSSPGSGKKTPSRSVKASPRRPSRVS 639
               ST+   R   +A+   +PS       P S   T   S  +  R P R S
Sbjct: 578 ----STVLLTRMPPSASPTGMPSRTSPTGMPSSALLTKMDSTASITRTPPRAS 626



 Score = 30.0 bits (66), Expect = 8.5
 Identities = 47/219 (21%), Positives = 80/219 (36%), Gaps = 24/219 (10%)

Query: 444 TPVREESTAKKLAGTNSSSLKATAIDQISISACSQAETSYGLGKFETRPSEFAEKTTNGH 503
           +P R  STA      + +SL  T      +   S+A  +       T P    + TT+  
Sbjct: 12  SPTRTPSTASLTGTPSRASLTGTPSTASLMGTPSRASLT------GTPPRASLKGTTSM- 64

Query: 504 KTDPDCKLSDSCGSISKADHSGSLDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLL 563
                  +S S  S+++   S  L  T    + ++ P          ++ T T    +L+
Sbjct: 65  ---ASLMVSPSRASLTRMQSSSLLTRTPSMASLKRMPP--------RASRTRTLPRASLM 113

Query: 564 LNPKSQESGGTESAANPTPSPIRKNQESTLEENRQTKTATSLSLPSDPMGDSSPGSGKKT 623
             P +     + S A+ T +P R +   T        TA +L++PS      +P     T
Sbjct: 114 RRPSTASLTRSPSRASLTTTPSRASLSMT------PSTAAALTMPSRASLTRTPPRASLT 167

Query: 624 PSRSVKASPRRPSRVSEFLKEQKLNVTAAAAQVGLTPGD 662
            + S  +  R P R S      + + T   +   LT  D
Sbjct: 168 MTPSTASLTRTPPRASPTGMPSRTSPTGMPSTASLTKMD 206


>gi|27262645 ataxin 2 related protein isoform B [Homo sapiens]
          Length = 1062

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 56/212 (26%), Positives = 83/212 (39%), Gaps = 29/212 (13%)

Query: 100 PQLPGSSQPAASAP----SSAAGRDLIHTPLTMPANQHTCQSIPGD----QPNAITSSMP 151
           PQ     QPA++ P    ++AAG  L+          +  Q  PG     QP A   S P
Sbjct: 753 PQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQP 812

Query: 152 EDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGTVQT--PVTAARVV 209
             + M     SN       S P   V SS+    S E P+P+ +  TV    P  A ++ 
Sbjct: 813 VFAPMLQ---SNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLH 869

Query: 210 SHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTP 269
           +H   P   P G +      S+  +  P+  ++G    + P + +  PQ        P  
Sbjct: 870 AHQPQPATTPTGSQP----QSQHAAPSPVQHQAG----QAPHLGSGQPQQNLY---HPGA 918

Query: 270 LTSEPSACPPGPEKVPLPAQRQMSRFKEASTM 301
           LT  P + PPGP      AQ   S F + + +
Sbjct: 919 LTGTPPSLPPGPS-----AQSPQSSFPQPAAV 945



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 72/302 (23%), Positives = 99/302 (32%), Gaps = 43/302 (14%)

Query: 9    RSAKTSLIAASGKEDDLGEPQAASPRHRPAL-----LCKNANGFSGAPAEPDLSPRAAAE 63
            R AK SL     +  D  +P +A P  + A      L       S  P  P   P     
Sbjct: 745  RGAKGSL---PPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFP--GQP 799

Query: 64   ALMQVCEHETTQPDM-----SSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAG 118
            A+MQ   H  +QP       S+P +       P    S   PQ P + QP   A  +   
Sbjct: 800  AMMQPMAHYPSQPVFAPMLQSNPRMLTSGSH-PQAIVSSSTPQYPSAEQPTPQALYATVH 858

Query: 119  RDLIHTPLTMPANQHTCQSIP-GDQP---NAITSSMPEDS-----LMRSQRTSNREQP-- 167
            +   H    + A+Q    + P G QP   +A  S +   +     L   Q   N   P  
Sbjct: 859  QSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGA 918

Query: 168  ---EKPSCPVGGVLSSSKDQVSCEFPSPETIQGT--VQTP---VTAARVV-SHSSSPVGG 218
                 PS P G    S +      FP P  +      Q P      A V  +H  + +  
Sbjct: 919  LTGTPPSLPPGPSAQSPQSS----FPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITA 974

Query: 219  PEGERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACP 278
                  GA    ++    P     G     Q +V  SG    ++ TP P P    P    
Sbjct: 975  APPPHPGAPHPPQVMLLHPPQSHGG---PPQGAVPQSGVPALSASTPSPYPYIGHPQGEQ 1031

Query: 279  PG 280
            PG
Sbjct: 1032 PG 1033


>gi|27262649 ataxin 2 related protein isoform C [Homo sapiens]
          Length = 1097

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 56/212 (26%), Positives = 83/212 (39%), Gaps = 29/212 (13%)

Query: 100 PQLPGSSQPAASAP----SSAAGRDLIHTPLTMPANQHTCQSIPGD----QPNAITSSMP 151
           PQ     QPA++ P    ++AAG  L+          +  Q  PG     QP A   S P
Sbjct: 753 PQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQP 812

Query: 152 EDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGTVQT--PVTAARVV 209
             + M     SN       S P   V SS+    S E P+P+ +  TV    P  A ++ 
Sbjct: 813 VFAPMLQ---SNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLH 869

Query: 210 SHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTP 269
           +H   P   P G +      S+  +  P+  ++G    + P + +  PQ        P  
Sbjct: 870 AHQPQPATTPTGSQP----QSQHAAPSPVQHQAG----QAPHLGSGQPQQNLY---HPGA 918

Query: 270 LTSEPSACPPGPEKVPLPAQRQMSRFKEASTM 301
           LT  P + PPGP      AQ   S F + + +
Sbjct: 919 LTGTPPSLPPGPS-----AQSPQSSFPQPAAV 945



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 72/302 (23%), Positives = 99/302 (32%), Gaps = 43/302 (14%)

Query: 9    RSAKTSLIAASGKEDDLGEPQAASPRHRPAL-----LCKNANGFSGAPAEPDLSPRAAAE 63
            R AK SL     +  D  +P +A P  + A      L       S  P  P   P     
Sbjct: 745  RGAKGSL---PPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFP--GQP 799

Query: 64   ALMQVCEHETTQPDM-----SSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAG 118
            A+MQ   H  +QP       S+P +       P    S   PQ P + QP   A  +   
Sbjct: 800  AMMQPMAHYPSQPVFAPMLQSNPRMLTSGSH-PQAIVSSSTPQYPSAEQPTPQALYATVH 858

Query: 119  RDLIHTPLTMPANQHTCQSIP-GDQP---NAITSSMPEDS-----LMRSQRTSNREQP-- 167
            +   H    + A+Q    + P G QP   +A  S +   +     L   Q   N   P  
Sbjct: 859  QSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGA 918

Query: 168  ---EKPSCPVGGVLSSSKDQVSCEFPSPETIQGT--VQTP---VTAARVV-SHSSSPVGG 218
                 PS P G    S +      FP P  +      Q P      A V  +H  + +  
Sbjct: 919  LTGTPPSLPPGPSAQSPQSS----FPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITA 974

Query: 219  PEGERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACP 278
                  GA    ++    P     G     Q +V  SG    ++ TP P P    P    
Sbjct: 975  APPPHPGAPHPPQVMLLHPPQSHGG---PPQGAVPQSGVPALSASTPSPYPYIGHPQGEQ 1031

Query: 279  PG 280
            PG
Sbjct: 1032 PG 1033


>gi|27262647 ataxin 2 related protein isoform A [Homo sapiens]
          Length = 1075

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 56/212 (26%), Positives = 83/212 (39%), Gaps = 29/212 (13%)

Query: 100 PQLPGSSQPAASAP----SSAAGRDLIHTPLTMPANQHTCQSIPGD----QPNAITSSMP 151
           PQ     QPA++ P    ++AAG  L+          +  Q  PG     QP A   S P
Sbjct: 753 PQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQP 812

Query: 152 EDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGTVQT--PVTAARVV 209
             + M     SN       S P   V SS+    S E P+P+ +  TV    P  A ++ 
Sbjct: 813 VFAPMLQ---SNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLH 869

Query: 210 SHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTP 269
           +H   P   P G +      S+  +  P+  ++G    + P + +  PQ        P  
Sbjct: 870 AHQPQPATTPTGSQP----QSQHAAPSPVQHQAG----QAPHLGSGQPQQNLY---HPGA 918

Query: 270 LTSEPSACPPGPEKVPLPAQRQMSRFKEASTM 301
           LT  P + PPGP      AQ   S F + + +
Sbjct: 919 LTGTPPSLPPGPS-----AQSPQSSFPQPAAV 945



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 72/302 (23%), Positives = 99/302 (32%), Gaps = 43/302 (14%)

Query: 9    RSAKTSLIAASGKEDDLGEPQAASPRHRPAL-----LCKNANGFSGAPAEPDLSPRAAAE 63
            R AK SL     +  D  +P +A P  + A      L       S  P  P   P     
Sbjct: 745  RGAKGSL---PPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFP--GQP 799

Query: 64   ALMQVCEHETTQPDM-----SSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAG 118
            A+MQ   H  +QP       S+P +       P    S   PQ P + QP   A  +   
Sbjct: 800  AMMQPMAHYPSQPVFAPMLQSNPRMLTSGSH-PQAIVSSSTPQYPSAEQPTPQALYATVH 858

Query: 119  RDLIHTPLTMPANQHTCQSIP-GDQP---NAITSSMPEDS-----LMRSQRTSNREQP-- 167
            +   H    + A+Q    + P G QP   +A  S +   +     L   Q   N   P  
Sbjct: 859  QSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGA 918

Query: 168  ---EKPSCPVGGVLSSSKDQVSCEFPSPETIQGT--VQTP---VTAARVV-SHSSSPVGG 218
                 PS P G    S +      FP P  +      Q P      A V  +H  + +  
Sbjct: 919  LTGTPPSLPPGPSAQSPQSS----FPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITA 974

Query: 219  PEGERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACP 278
                  GA    ++    P     G     Q +V  SG    ++ TP P P    P    
Sbjct: 975  APPPHPGAPHPPQVMLLHPPQSHGG---PPQGAVPQSGVPALSASTPSPYPYIGHPQGEQ 1031

Query: 279  PG 280
            PG
Sbjct: 1032 PG 1033


>gi|27262651 ataxin 2 related protein isoform D [Homo sapiens]
          Length = 1044

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 56/212 (26%), Positives = 83/212 (39%), Gaps = 29/212 (13%)

Query: 100 PQLPGSSQPAASAP----SSAAGRDLIHTPLTMPANQHTCQSIPGD----QPNAITSSMP 151
           PQ     QPA++ P    ++AAG  L+          +  Q  PG     QP A   S P
Sbjct: 753 PQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQP 812

Query: 152 EDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQVSCEFPSPETIQGTVQT--PVTAARVV 209
             + M     SN       S P   V SS+    S E P+P+ +  TV    P  A ++ 
Sbjct: 813 VFAPMLQ---SNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLH 869

Query: 210 SHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTP 269
           +H   P   P G +      S+  +  P+  ++G    + P + +  PQ        P  
Sbjct: 870 AHQPQPATTPTGSQP----QSQHAAPSPVQHQAG----QAPHLGSGQPQQNLY---HPGA 918

Query: 270 LTSEPSACPPGPEKVPLPAQRQMSRFKEASTM 301
           LT  P + PPGP      AQ   S F + + +
Sbjct: 919 LTGTPPSLPPGPS-----AQSPQSSFPQPAAV 945


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 64/300 (21%), Positives = 106/300 (35%), Gaps = 28/300 (9%)

Query: 50   APAEPDLSPRAAAEALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPA 109
            AP+      +A +++L+   +    QP    P  F++  +      +P       SS   
Sbjct: 2424 APSPSSRMGQAPSQSLLPPAQD---QPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAV 2480

Query: 110  ASAPSSAAGRD-LIHTPLTMPANQHTCQSIP-----GDQPNAITSSMP----EDSLMRSQ 159
            A+  SSA   + ++  P   P   H+    P       QP+A+ +  P      S   S 
Sbjct: 2481 ATTTSSAGDHNGMLSVPA--PGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSS 2538

Query: 160  RTSNREQPEKPSCPVGGVLSSSKDQVSCEFP-SPETIQGTVQTPVTAARVVSHSSSPVGG 218
             +S+       S       SSS D      P  PE     V +P  A +       P   
Sbjct: 2539 SSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEP 2598

Query: 219  PEGERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACP 278
               +R+     S   S    +  S  S +   S ++S    ++S +      +S PS   
Sbjct: 2599 TPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS-----SSSPSPAK 2653

Query: 279  PGPEKVPLPAQRQMSRFKEASTMTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSPS 338
            PGP+ +P PA  +            +  S     P  + +D+   + + VE R  S  PS
Sbjct: 2654 PGPQALPKPASPK-------KPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPS 2706



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 115/586 (19%), Positives = 199/586 (33%), Gaps = 56/586 (9%)

Query: 76   PDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLI--HTPLTMPANQH 133
            P MS+ G+   + + PA          P ++  +    +SAA  +L    TP  +P   +
Sbjct: 2197 PSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTP-AIPTAVN 2255

Query: 134  TCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLS-------------- 179
               S       A+  + P  ++  S    N   P  P+ P   +                
Sbjct: 2256 LADSRTPAAAAAMNLASPRTAVAPS--AVNLADPRTPTAPAVNLAGARTPAALAALSLTG 2313

Query: 180  SSKDQVSCEFPSPETIQGTVQTPVTAARV---VSHSSSPVGGPEGERQGAICDSEMRSCK 236
            S     +  +PS      T Q P +A  V    +H+++PV         A+  + + S +
Sbjct: 2314 SGTPPTAANYPSSSR---TPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSAR 2370

Query: 237  PLTRESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMS--R 294
                 SG +    P V  S  +  +  T  P  L    S  PP       P+Q +M+  R
Sbjct: 2371 MAPALSGANLTS-PRVPLSAYERVSGRTSPPL-LDRARSRTPPSA-----PSQSRMTSER 2423

Query: 295  FKEASTMTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFE 354
                S+   QA S+    P++    + V +  S +SR        L A        +   
Sbjct: 2424 APSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRC-------LIAQTTPVAGSQSLS 2476

Query: 355  QEQLRVICHSSGSHT--LELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLAS 412
               +     S+G H   L +    +   +  + P         A AA   A +R +  +S
Sbjct: 2477 SGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSS 2536

Query: 413  LPGGVLKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQIS 472
                   +SS +  SS++              PV+ E   K++     +  +A  + +  
Sbjct: 2537 SSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEA--VREGR 2594

Query: 473  ISACSQAETSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSGSLDPTNK 532
                + A+         +  S  +  +++   +      S S  S S +  S S  P   
Sbjct: 2595 PPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKP 2654

Query: 533  GDAREKKPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQEST 592
            G     KPASP+     E            L + +S      E    P+P P  ++Q+S+
Sbjct: 2655 GPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVE-RRRPSPQPSPRDQQSS 2713

Query: 593  LEENRQTKTATSLSLPSDPMGDS-SPGSGKKTPSRSVKASPRRPSR 637
              E    +            GDS SP   ++  + S +    R SR
Sbjct: 2714 SSERGSRR---------GQRGDSRSPSHKRRRETPSPRPMRHRSSR 2750



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 106/554 (19%), Positives = 196/554 (35%), Gaps = 67/554 (12%)

Query: 100  PQLPGSSQPAASAPSSAAGRDLIHTPLTMPANQHTCQSIPGDQPNAITSSMPEDSLMRSQ 159
            P+    + P  S   S+  +    TP   P    +  S P  Q +   S     S     
Sbjct: 786  PKQKSQTPPRRSRSGSSQPKAKSRTP---PRRSRSSSSPPPKQKSKTPSRQSHSSSSPHP 842

Query: 160  RTSNREQPEKPSC--PVGGVLSSSKDQVSCEFPSPETIQGTVQTPVTAARVVS-HSSSPV 216
            +  +   P + S   P     S +  + SC   SP+        P   +R  S HS S  
Sbjct: 843  KVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPD--------PELKSRTPSRHSCSGS 894

Query: 217  GGPEGERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSA 276
              P  +       S  RS  P  +       +Q S + S     + VT + TP  S   +
Sbjct: 895  SPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVS 954

Query: 277  CPPGPEKVPLPAQRQMSRFKEASTMTNQAESEIK-EVPSRAWQDAEVQAVASVESRSVST 335
                 E   LP        + + + ++  ++++K E P R      +     V++++   
Sbjct: 955  PCSNVESRLLP--------RYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQT-PP 1005

Query: 336  SPSILTAFLKESRAPEHFEQEQLRVICHSS------------------GSHTLELS-DST 376
             PS+  +   +S  P+   ++ L   C  S                  G  +L+L   S 
Sbjct: 1006 GPSLSGS---KSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQ 1062

Query: 377  LAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVLKTSSINLVSSNAQHTCKE 436
             +P   S      P+V  + + +ES + Q +++ +  P G    SS  +    ++   ++
Sbjct: 1063 TSPDHRSDTSS--PEV--RQSHSESPSLQSKSQTS--PKGGRSRSSSPVTELASRSPIRQ 1116

Query: 437  DGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISACSQAETSYGLGKFETRPSEFA 496
            D      +P+ +   + + +   S S     +D  S+   S+ ET+    K    P E A
Sbjct: 1117 DRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDA 1176

Query: 497  EKTTNGHKTDPDCKLSDSCGSISKADHSGS---LDPTNKGDAREKKPA--SPQVVKEKES 551
              +    K        D        D   S      T +   RE+  A  SP+  ++  +
Sbjct: 1177 TASPPRQK--------DKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSA 1228

Query: 552  TGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQESTLEENRQTKTATSLSLPSDP 611
              T + D + + +  KS+E  G     +   S +++   S  E + + +   ++SL  D 
Sbjct: 1229 LPTSSQDEELMEVVEKSEEPAG--QILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQ 1286

Query: 612  MGDSSPGSGKKTPS 625
                +     + PS
Sbjct: 1287 SQSQASLEAVEVPS 1300



 Score = 39.3 bits (90), Expect = 0.014
 Identities = 164/772 (21%), Positives = 274/772 (35%), Gaps = 128/772 (16%)

Query: 66   MQVCEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTP 125
            +Q+     T PD  S     EV+++ +      +P L   SQ      S   GR    +P
Sbjct: 1055 LQLKGQSQTSPDHRSDTSSPEVRQSHSE-----SPSLQSKSQT-----SPKGGRSRSSSP 1104

Query: 126  LTMPANQHTCQSIPGD---QPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSK 182
            +T  A++   +   G+    P   +   PE S  +S  +S       P+     +L  S+
Sbjct: 1105 VTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSY------PTVDSNSLLGQSR 1158

Query: 183  DQVSCEFPSPETIQGTVQTPVTAARVVSHSS-SPVGGPEGERQGAICDSEMRSCKPLTRE 241
             + +    S E +    Q   TA+        SP    +      +    +R+  P    
Sbjct: 1159 LETA---ESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRT--PPRER 1213

Query: 242  SGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRF----KE 297
            SG           +G    T       P +S+        EK   PA + +S      KE
Sbjct: 1214 SG-----------AGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKE 1262

Query: 298  ASTMTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFEQEQ 357
             ST   ++  E++E P+ +    + Q+ AS+E+  V   PS+ +++     +PEH E   
Sbjct: 1263 MSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEV---PSMASSWGGPHFSPEHKELSN 1319

Query: 358  LRVICHSSGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGV 417
              +  +S GS  LE  +S   P  +    G   +V       E       N+L + P   
Sbjct: 1320 SPLRENSFGS-PLEFRNS--GPLGTEMNTGFSSEVK------EDLNGPFLNQLETDPSLD 1370

Query: 418  LKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISACS 477
            +K  S      ++     +    AGM+  +  S+    A   + S + +       S+ S
Sbjct: 1371 MKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERS-------SSAS 1423

Query: 478  QAETSYGLGKFETRPSEFAEK--------TTNGHK---TDPDCKLSDSCGSISKADHSGS 526
              E   GL +  +R S             T + H    + P  K      S  +++   S
Sbjct: 1424 SPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSS 1483

Query: 527  LDPTNKGDA---REKKPASPQV-----VKEKESTGTDTS-DAKTLLLNPKSQES---GGT 574
             +P         R + P+SP++       ++E +G+++S D KT+   P  Q S      
Sbjct: 1484 PEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQ 1543

Query: 575  ESAANPTPSPIRKNQESTLEENRQTKTATSLSLPS----DPMGDS----SPGSGKKTPSR 626
            E    P+ SP ++  ES    + + KT T L   S     P  DS    SP   +   S 
Sbjct: 1544 ELDVKPSASP-QERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSP 1602

Query: 627  SVKASPRRPSRV---SEFLKEQKLNVTAAAAQVGLT------------------------ 659
             VK  PR   R    S+   E K     A  +   +                        
Sbjct: 1603 EVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHP 1662

Query: 660  PGDKKKQLGADSKLQLK---------QSKRVRDVVWDEQGMTWEVYGASLDAESLGIAIQ 710
            P  +  + G+ S  + K         +S R    +  +  ++     AS   E+      
Sbjct: 1663 PKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPP 1722

Query: 711  NHLQR-QIREHEKLIKTQNSQTRRSISSDTSSNKKLRGRQHSVFQSMLQNFR 761
             H +   +   E   K+++S+ RRS SS  +     RGR  S     LQ  R
Sbjct: 1723 RHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSR 1774



 Score = 34.7 bits (78), Expect = 0.35
 Identities = 49/203 (24%), Positives = 73/203 (35%), Gaps = 29/203 (14%)

Query: 152 EDSLMRSQRTSNREQPEK-PSCPVGGVLSSSKDQVSCE-FPSPETI----QGTVQTPVTA 205
           E     +QR S+ E   K PS P        K++ +    PSPE      +    TP+ A
Sbjct: 312 EPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLA 371

Query: 206 ARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVT- 264
            R   H  SP       +  A          P +  S   +   P      PQ ++S + 
Sbjct: 372 ER---HGGSP-------QPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESS 421

Query: 265 ---PQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEASTMTNQAESEIK------EVPSR 315
              PQPT ++   S+ P  P+  P P   +      + T  N++    K        PSR
Sbjct: 422 PPSPQPTKVSRHASSSPESPKPAPAPGSHR--EISSSPTSKNRSHGRAKRDKSHSHTPSR 479

Query: 316 AWQDAEVQAVASVESRSVSTSPS 338
               +   A A    RS S +P+
Sbjct: 480 RMGRSRSPATAK-RGRSRSRTPT 501



 Score = 33.5 bits (75), Expect = 0.77
 Identities = 112/516 (21%), Positives = 187/516 (36%), Gaps = 51/516 (9%)

Query: 147  TSSMPEDSLMRSQRTSNREQPEKPSCPV-GGVLSSSKDQVSCEFPSPETIQGTVQTPVTA 205
            +S +  D++ ++  +SN    +  S PV   V  +   + S    SPE   G  +TP   
Sbjct: 1383 SSELSPDAVEKAGMSSN----QSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRR 1438

Query: 206  ARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTP 265
            +R  S      G     R      S      P T   G SE        S P+      P
Sbjct: 1439 SRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSE------CDSSPE------P 1486

Query: 266  QPTPLTSEP-SACPPGPE--KVPLPAQRQMSRFKEASTMTNQAESEI-KEVPSRAWQDAE 321
            +  P T  P S  P  PE     L  QR+ S  + +      A + + +   S + Q+ +
Sbjct: 1487 KALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELD 1546

Query: 322  VQAVASVESRSVSTSP-----SILTAFLKESRA---PEHFEQEQLRVICHSSGSHTLELS 373
            V+  AS + RS S S         T   + SR+   PE   + +L      SGS   E+ 
Sbjct: 1547 VKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSP-EVK 1605

Query: 374  DSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVLKTSSINLVSSNAQH- 432
            D   A   +       P+     A A     +R    +S  G        +   S+ +H 
Sbjct: 1606 DKPRAAPRAQSGSDSSPE---PKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHP 1662

Query: 433  ----TCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATA-IDQISISACSQAET-SYGLG 486
                T +   R +     +  +  ++ +  +S  L   A + + S SA S  ET S    
Sbjct: 1663 PKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPP 1722

Query: 487  KFETRPS----EFAEKTTNGHK----TDPDCKLSDSCGSISKADHSGSLDPTNKGDAREK 538
            +    PS    E AEK+ +  +    + P  K +   G  S +     L  +     REK
Sbjct: 1723 RHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGR-SPSPKPRGLQRSRSRSRREK 1781

Query: 539  KPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQESTLEENRQ 598
               + +  +   S  T     ++   +  ++   G   +   + SP R+    T    R+
Sbjct: 1782 TRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRG--GSGYHSRSPARQESSRTSSRRRR 1839

Query: 599  TKTATSLSLPSDPMGDSSPGSGKKTPSRSVKASPRR 634
             ++ T  +        +SP   K++ SR+  A+ RR
Sbjct: 1840 GRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRR 1875



 Score = 33.1 bits (74), Expect = 1.0
 Identities = 111/577 (19%), Positives = 181/577 (31%), Gaps = 52/577 (9%)

Query: 200  QTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQG 259
            +TP TA    S + SP         G+  D    +  P TR    S     ++ +S    
Sbjct: 2057 RTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSC 2116

Query: 260  TTSVTPQPTPL---TSEPSACPPGPEKVPLPAQRQMSRFKEASTMTNQAESEIKEVPSRA 316
             +  +  PTPL    S     P G  + P+   +Q              + +   VP   
Sbjct: 2117 FSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENH 2176

Query: 317  WQDAEVQAVASVESRSVSTSPSILTAFL--KESRAPEHFEQEQLRVICHSSGSHTLELSD 374
             Q     A+ ++   +    PS+  A L  + S+ P       LR    ++ +  +  + 
Sbjct: 2177 AQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAAS 2236

Query: 375  STLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVLKTSSINLVSSNAQHTC 434
            +      S++ P I   V++  A + + A      LAS P   +  S++NL       T 
Sbjct: 2237 AAAMNLASARTPAIPTAVNL--ADSRTPAAAAAMNLAS-PRTAVAPSAVNLADPRTP-TA 2292

Query: 435  KEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISACSQAETSYGL----GKFET 490
                     TP      A        S    TA +  S S   QA  S  L        T
Sbjct: 2293 PAVNLAGARTP-----AALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHAT 2347

Query: 491  RPSEFAEKTTNGHKTDPDCKLSDSCGSISKAD-------------HSGSLDPTNKGDARE 537
             P   A   T           +    ++S A+              SG   P     AR 
Sbjct: 2348 APVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARS 2407

Query: 538  KKPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQESTLEENR 597
            + P S        S    +  ++      +S      +   +P PS         + +  
Sbjct: 2408 RTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQT- 2466

Query: 598  QTKTATSLSLPSDPMGDSSPGSGKKTPSRSVKASPRRPSRVSEFLKEQKLNVTAAAAQVG 657
             T  A S SL S  +  ++  +G      SV A     S V E            +A   
Sbjct: 2467 -TPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGE--PPASTGAQQPSALAA 2523

Query: 658  LTPGDKKKQLGADSKLQLKQSKRVRDVVWDEQGMTWEVYGASLDAESLGIAIQNHL---- 713
            L P  +++   + S      S             +     +S D+E   + +Q  +    
Sbjct: 2524 LQPAKERRSSSSSSSSSSSSSSSS-----SSSSSSSSSGSSSSDSEGSSLPVQPEVALKR 2578

Query: 714  --------QRQIREHEKLIKTQNSQTRRSISSDTSSN 742
                    +  +RE      T   + RRS SS +SS+
Sbjct: 2579 VPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSS 2615


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.306    0.121    0.340 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,568,471
Number of Sequences: 37866
Number of extensions: 1788693
Number of successful extensions: 11909
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 658
Number of HSP's that attempted gapping in prelim test: 9562
Number of HSP's gapped (non-prelim): 2522
length of query: 776
length of database: 18,247,518
effective HSP length: 110
effective length of query: 666
effective length of database: 14,082,258
effective search space: 9378783828
effective search space used: 9378783828
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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