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Search of human proteins with 106049295
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|106049295 pyruvate carboxylase precursor [Homo sapiens]
(1178 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|106049528 pyruvate carboxylase precursor [Homo sapiens] 2349 0.0
gi|106049295 pyruvate carboxylase precursor [Homo sapiens] 2349 0.0
gi|106049292 pyruvate carboxylase precursor [Homo sapiens] 2349 0.0
gi|65506442 propionyl-Coenzyme A carboxylase, alpha polypeptide ... 377 e-104
gi|189095269 propionyl-Coenzyme A carboxylase, alpha polypeptide... 377 e-104
gi|116805327 methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) pr... 377 e-104
gi|38679977 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo ... 223 6e-58
gi|38679974 acetyl-Coenzyme A carboxylase alpha isoform 4 [Homo ... 223 6e-58
gi|38679971 acetyl-Coenzyme A carboxylase alpha isoform 3 [Homo ... 223 6e-58
gi|38679967 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo ... 223 6e-58
gi|38679960 acetyl-Coenzyme A carboxylase alpha isoform 1 [Homo ... 223 6e-58
gi|134142062 acetyl-Coenzyme A carboxylase beta [Homo sapiens] 215 2e-55
gi|18105007 carbamoylphosphate synthetase 2/aspartate transcarba... 79 3e-14
gi|169790915 carbamoyl-phosphate synthetase 1 isoform a precurso... 59 2e-08
gi|21361331 carbamoyl-phosphate synthetase 1 isoform b precursor... 59 2e-08
gi|170295797 carbamoyl-phosphate synthetase 1 isoform c [Homo sa... 56 2e-07
gi|109150422 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-l... 47 8e-05
gi|109150427 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-l... 47 8e-05
gi|62198232 3-hydroxy-3-methylglutaryl CoA lyase [Homo sapiens] 39 0.022
gi|219802034 nuclear factor related to kappaB binding protein is... 37 0.11
gi|23346420 nuclear factor related to kappaB binding protein iso... 37 0.11
gi|115387123 protocadherin 15 isoform CD1-4 precursor [Homo sapi... 32 2.7
gi|218505798 protocadherin 15 isoform CD1-10 precursor [Homo sap... 32 2.7
gi|218505785 protocadherin 15 isoform CD1-9 precursor [Homo sapi... 32 2.7
gi|218505783 protocadherin 15 isoform CD1-8 precursor [Homo sapi... 32 2.7
gi|218505781 protocadherin 15 isoform CD1-7 precursor [Homo sapi... 32 2.7
gi|218505779 protocadherin 15 isoform CD1-6 precursor [Homo sapi... 32 2.7
gi|218505777 protocadherin 15 isoform CD1-2 precursor [Homo sapi... 32 2.7
gi|218505775 protocadherin 15 isoform CD1-1 precursor [Homo sapi... 32 2.7
gi|53759113 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 2... 32 4.7
>gi|106049528 pyruvate carboxylase precursor [Homo sapiens]
Length = 1178
Score = 2349 bits (6087), Expect = 0.0
Identities = 1178/1178 (100%), Positives = 1178/1178 (100%)
Query: 1 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG 60
MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
Sbjct: 1 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG 60
Query: 61 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF 120
IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
Sbjct: 61 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF 120
Query: 121 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA 180
LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
Sbjct: 121 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA 180
Query: 181 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE 240
HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
Sbjct: 181 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE 240
Query: 241 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK 300
KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
Sbjct: 241 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK 300
Query: 301 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360
QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
Sbjct: 301 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360
Query: 361 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP 420
GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
Sbjct: 361 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP 420
Query: 421 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF 480
HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
Sbjct: 421 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF 480
Query: 481 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG 540
IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
Sbjct: 481 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG 540
Query: 541 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK 600
FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
Sbjct: 541 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK 600
Query: 601 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF 660
LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
Sbjct: 601 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF 660
Query: 661 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL 720
KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
Sbjct: 661 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL 720
Query: 721 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV 780
QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
Sbjct: 721 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV 780
Query: 781 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG 840
AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
Sbjct: 781 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG 840
Query: 841 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM 900
ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
Sbjct: 841 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM 900
Query: 901 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP 960
LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
Sbjct: 901 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP 960
Query: 961 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF 1020
EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
Sbjct: 961 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF 1020
Query: 1021 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL 1080
KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
Sbjct: 1021 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL 1080
Query: 1081 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL 1140
NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
Sbjct: 1081 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL 1140
Query: 1141 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE 1178
SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
Sbjct: 1141 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE 1178
>gi|106049295 pyruvate carboxylase precursor [Homo sapiens]
Length = 1178
Score = 2349 bits (6087), Expect = 0.0
Identities = 1178/1178 (100%), Positives = 1178/1178 (100%)
Query: 1 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG 60
MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
Sbjct: 1 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG 60
Query: 61 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF 120
IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
Sbjct: 61 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF 120
Query: 121 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA 180
LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
Sbjct: 121 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA 180
Query: 181 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE 240
HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
Sbjct: 181 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE 240
Query: 241 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK 300
KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
Sbjct: 241 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK 300
Query: 301 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360
QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
Sbjct: 301 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360
Query: 361 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP 420
GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
Sbjct: 361 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP 420
Query: 421 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF 480
HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
Sbjct: 421 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF 480
Query: 481 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG 540
IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
Sbjct: 481 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG 540
Query: 541 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK 600
FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
Sbjct: 541 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK 600
Query: 601 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF 660
LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
Sbjct: 601 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF 660
Query: 661 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL 720
KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
Sbjct: 661 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL 720
Query: 721 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV 780
QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
Sbjct: 721 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV 780
Query: 781 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG 840
AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
Sbjct: 781 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG 840
Query: 841 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM 900
ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
Sbjct: 841 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM 900
Query: 901 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP 960
LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
Sbjct: 901 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP 960
Query: 961 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF 1020
EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
Sbjct: 961 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF 1020
Query: 1021 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL 1080
KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
Sbjct: 1021 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL 1080
Query: 1081 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL 1140
NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
Sbjct: 1081 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL 1140
Query: 1141 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE 1178
SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
Sbjct: 1141 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE 1178
>gi|106049292 pyruvate carboxylase precursor [Homo sapiens]
Length = 1178
Score = 2349 bits (6087), Expect = 0.0
Identities = 1178/1178 (100%), Positives = 1178/1178 (100%)
Query: 1 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG 60
MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
Sbjct: 1 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG 60
Query: 61 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF 120
IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
Sbjct: 61 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF 120
Query: 121 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA 180
LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
Sbjct: 121 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA 180
Query: 181 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE 240
HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
Sbjct: 181 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE 240
Query: 241 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK 300
KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
Sbjct: 241 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK 300
Query: 301 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360
QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
Sbjct: 301 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360
Query: 361 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP 420
GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
Sbjct: 361 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP 420
Query: 421 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF 480
HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
Sbjct: 421 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF 480
Query: 481 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG 540
IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
Sbjct: 481 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG 540
Query: 541 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK 600
FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
Sbjct: 541 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK 600
Query: 601 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF 660
LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
Sbjct: 601 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF 660
Query: 661 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL 720
KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
Sbjct: 661 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL 720
Query: 721 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV 780
QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
Sbjct: 721 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV 780
Query: 781 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG 840
AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
Sbjct: 781 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG 840
Query: 841 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM 900
ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
Sbjct: 841 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM 900
Query: 901 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP 960
LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
Sbjct: 901 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP 960
Query: 961 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF 1020
EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
Sbjct: 961 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF 1020
Query: 1021 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL 1080
KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
Sbjct: 1021 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL 1080
Query: 1081 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL 1140
NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
Sbjct: 1081 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL 1140
Query: 1141 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE 1178
SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
Sbjct: 1141 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE 1178
>gi|65506442 propionyl-Coenzyme A carboxylase, alpha polypeptide
isoform a precursor [Homo sapiens]
Length = 728
Score = 377 bits (969), Expect = e-104
Identities = 202/452 (44%), Positives = 291/452 (64%), Gaps = 9/452 (1%)
Query: 35 KPIKKVMVANRGEIAIRVFRACTELGIRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPV- 93
K K++VANRGEIA RV R C ++GI+TVAI+S+ D +H + ADEA +G AP
Sbjct: 61 KTFDKILVANRGEIACRVIRTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGP--APTS 118
Query: 94 QAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVVRKMGDKV 153
++YL++ I++ K+ AVHPGYGFLSE +FA+ V FIGP ++ MGDK+
Sbjct: 119 KSYLNMDAIMEAIKKTRAQAVHPGYGFLSENKEFARCLAAEDVVFIGPDTHAIQAMGDKI 178
Query: 154 EARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEEL 213
E++ +A A V +PG D + EA + G+P++ KA+ GGGG+GMR+ EE
Sbjct: 179 ESKLLAKKAEVNTIPGFDGVVKDAEEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEET 238
Query: 214 EENYTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQK 273
+ + + EA ++FG+ L +EKFI+ PRHIE+Q+LGD++GN L L ER+CSIQRR+QK
Sbjct: 239 RDGFRLSSQEAASSFGDDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQK 298
Query: 274 VVEIAPAAHLDPQLRTRLTSDSVKLAKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEH 333
VVE AP+ LD + R + +V LA+ V Y +AGTVEFLVD YF+E+N+RLQVEH
Sbjct: 299 VVEEAPSIFLDAETRRAMGEQAVALARAVKYSSAGTVEFLVDSKKNFYFLEMNTRLQVEH 358
Query: 334 TVTEEITDVDLVHAQIHVAEGRSLPDLGLRQENIRINGCAIQCRVTTEDPARSF-QPDTG 392
VTE IT +DLV I VA+G L +Q +IRING A++CRV EDP +SF P G
Sbjct: 359 PVTECITGLDLVQEMIRVAKGYPLRH---KQADIRINGWAVECRVYAEDPYKSFGLPSIG 415
Query: 393 RIEVFRSGEGM-GIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFR 451
R+ ++ + G+R+D+ G+ IS +YD ++ K+I +G D A +M+ AL +
Sbjct: 416 RLSQYQEPLHLPGVRVDSGIQ-PGSDISIYYDPMISKLITYGSDRTEALKRMADALDNYV 474
Query: 452 VRGVKTNIAFLQNVLNNQQFLAGTVDTQFIDE 483
+RGV NIA L+ V+ N +F+ G + T+F+ +
Sbjct: 475 IRGVTHNIALLREVIINSRFVKGDISTKFLSD 506
Score = 62.8 bits (151), Expect = 2e-09
Identities = 30/76 (39%), Positives = 46/76 (60%)
Query: 1103 KALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVLSAMKMETVVTSPMEGTVRKVHV 1162
K +D + +PMPG V+ + V G VA+GQ +CV+ AMKM+ +T+ GTV+ VH
Sbjct: 653 KVTEDTSSVLRSPMPGVVVAVSVKPGDAVAEGQEICVIEAMKMQNSMTAGKTGTVKSVHC 712
Query: 1163 TKDMTLEGDDLILEIE 1178
T+ DL++E+E
Sbjct: 713 QAGDTVGEGDLLVELE 728
>gi|189095269 propionyl-Coenzyme A carboxylase, alpha polypeptide
isoform b [Homo sapiens]
Length = 702
Score = 377 bits (969), Expect = e-104
Identities = 202/452 (44%), Positives = 291/452 (64%), Gaps = 9/452 (1%)
Query: 35 KPIKKVMVANRGEIAIRVFRACTELGIRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPV- 93
K K++VANRGEIA RV R C ++GI+TVAI+S+ D +H + ADEA +G AP
Sbjct: 35 KTFDKILVANRGEIACRVIRTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGP--APTS 92
Query: 94 QAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVVRKMGDKV 153
++YL++ I++ K+ AVHPGYGFLSE +FA+ V FIGP ++ MGDK+
Sbjct: 93 KSYLNMDAIMEAIKKTRAQAVHPGYGFLSENKEFARCLAAEDVVFIGPDTHAIQAMGDKI 152
Query: 154 EARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEEL 213
E++ +A A V +PG D + EA + G+P++ KA+ GGGG+GMR+ EE
Sbjct: 153 ESKLLAKKAEVNTIPGFDGVVKDAEEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEET 212
Query: 214 EENYTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQK 273
+ + + EA ++FG+ L +EKFI+ PRHIE+Q+LGD++GN L L ER+CSIQRR+QK
Sbjct: 213 RDGFRLSSQEAASSFGDDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQK 272
Query: 274 VVEIAPAAHLDPQLRTRLTSDSVKLAKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEH 333
VVE AP+ LD + R + +V LA+ V Y +AGTVEFLVD YF+E+N+RLQVEH
Sbjct: 273 VVEEAPSIFLDAETRRAMGEQAVALARAVKYSSAGTVEFLVDSKKNFYFLEMNTRLQVEH 332
Query: 334 TVTEEITDVDLVHAQIHVAEGRSLPDLGLRQENIRINGCAIQCRVTTEDPARSF-QPDTG 392
VTE IT +DLV I VA+G L +Q +IRING A++CRV EDP +SF P G
Sbjct: 333 PVTECITGLDLVQEMIRVAKGYPLRH---KQADIRINGWAVECRVYAEDPYKSFGLPSIG 389
Query: 393 RIEVFRSGEGM-GIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFR 451
R+ ++ + G+R+D+ G+ IS +YD ++ K+I +G D A +M+ AL +
Sbjct: 390 RLSQYQEPLHLPGVRVDSGIQ-PGSDISIYYDPMISKLITYGSDRTEALKRMADALDNYV 448
Query: 452 VRGVKTNIAFLQNVLNNQQFLAGTVDTQFIDE 483
+RGV NIA L+ V+ N +F+ G + T+F+ +
Sbjct: 449 IRGVTHNIALLREVIINSRFVKGDISTKFLSD 480
Score = 62.8 bits (151), Expect = 2e-09
Identities = 30/76 (39%), Positives = 46/76 (60%)
Query: 1103 KALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVLSAMKMETVVTSPMEGTVRKVHV 1162
K +D + +PMPG V+ + V G VA+GQ +CV+ AMKM+ +T+ GTV+ VH
Sbjct: 627 KVTEDTSSVLRSPMPGVVVAVSVKPGDAVAEGQEICVIEAMKMQNSMTAGKTGTVKSVHC 686
Query: 1163 TKDMTLEGDDLILEIE 1178
T+ DL++E+E
Sbjct: 687 QAGDTVGEGDLLVELE 702
>gi|116805327 methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)
precursor [Homo sapiens]
Length = 725
Score = 377 bits (967), Expect = e-104
Identities = 214/540 (39%), Positives = 308/540 (57%), Gaps = 9/540 (1%)
Query: 37 IKKVMVANRGEIAIRVFRACTELGIRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAY 96
I KV++ANRGEIA RV R +LG++TVA+YSE D MH ADEAY IG + Q+Y
Sbjct: 49 ITKVLIANRGEIACRVMRTAKKLGVQTVAVYSEADRNSMHVDMADEAYSIGPAPSQ-QSY 107
Query: 97 LHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEAR 156
L + II+VAK + A+HPG GFLSE +FA+ C+ G+ FIGP P +R MG K ++
Sbjct: 108 LSMEKIIQVAKTSAAQAIHPGCGFLSENMEFAELCKQEGIIFIGPPPSAIRDMGIKSTSK 167
Query: 157 AIAIAAGVPVVPGTDAPITSLHEAHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEEN 216
+I AAGVPVV G S E + G+P++ KA GGGG+GMR+V S +E +E
Sbjct: 168 SIMAAAGVPVVEGYHGEDQSDQCLKEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQ 227
Query: 217 YTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVE 276
A EA +F + A+ +EKF++ PRH+EVQ+ GD +GN ++L+ERDCS+QRRHQK++E
Sbjct: 228 LESARREAKKSFNDDAMLIEKFVDTPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIE 287
Query: 277 IAPAAHLDPQLRTRLTSDSVKLAKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVT 336
APA + ++R +L +V+ AK V Y AGTVEF++D F+E+N+RLQVEH VT
Sbjct: 288 EAPAPGIKSEVRKKLGEAAVRAAKAVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVT 347
Query: 337 EEITDVDLVHAQIHVAEGRSLPDLGLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEV 396
E IT DLV Q+ +A G +P L QE I + G A + R+ EDP+ +F P G +
Sbjct: 348 EMITGTDLVEWQLRIAAGEKIP---LSQEEITLQGHAFEARIYAEDPSNNFMPVAGPLVH 404
Query: 397 FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVK 456
+ QG +S HYD ++ K++ D A TK+ +L ++ + G+
Sbjct: 405 LSTPRADPSTRIETGVRQGDEVSVHYDPMIAKLVVWAADRQAALTKLRYSLRQYNIVGLH 464
Query: 457 TNIAFLQNVLNNQQFLAGTVDTQFIDE-NPELFQLRPAQNRAQKLLHYLGHVMVNGPTTP 515
TNI FL N+ + +F AG V T FI + + +L R A + LG ++ T
Sbjct: 465 TNIDFLLNLSGHPEFEAGNVHTDFIPQHHKQLLLSRKAAAKESLCQAALGLILKEKAMTD 524
Query: 516 IPVKASPSPTDPVVPAVPIGPPPAGFRDILLREGPEGFARAVR-NHPG---LLLMDTTFR 571
+ P + + R++ L++G A AV NH G + + D TF+
Sbjct: 525 TFTLQAHDQFSPFSSSSGRRLNISYTRNMTLKDGKNNVAIAVTYNHDGSYSMQIEDKTFQ 584
Score = 47.8 bits (112), Expect = 6e-05
Identities = 29/64 (45%), Positives = 35/64 (54%), Gaps = 5/64 (7%)
Query: 1102 PKALKDVKGQIG-----APMPGKVIDIKVVAGAKVAKGQPLCVLSAMKMETVVTSPMEGT 1156
PK L V Q APM G + + V AG KV G L V+ AMKME + SP +GT
Sbjct: 634 PKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDGT 693
Query: 1157 VRKV 1160
V+KV
Sbjct: 694 VKKV 697
>gi|38679977 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo
sapiens]
Length = 2346
Score = 223 bits (569), Expect = 6e-58
Identities = 153/510 (30%), Positives = 248/510 (48%), Gaps = 73/510 (14%)
Query: 35 KPIKKVMVANRGEIAIRVFRAC---------TELGIRTVAIYSEQDT-GQMHRQKADEAY 84
K I+KV++AN G A++ R+ E IR V + + +D K + Y
Sbjct: 116 KVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHY 175
Query: 85 LIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPE 144
+ G Y ++ I+ +AK V AV G+G SE + G+ F+GP +
Sbjct: 176 VPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQ 235
Query: 145 VVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTY----------------- 187
+ +GDK+ + +A AG+P +P + + + + ++FS
Sbjct: 236 AMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVD 295
Query: 188 ---------GFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKF 238
G+P++ KA+ GGGG+G+R V++ ++ + + + A +FV +
Sbjct: 296 DGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADD----FPNLFRQVQAEVPGSPIFVMRL 351
Query: 239 IEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKL 298
++ RH+EVQIL DQYGN + L+ RDCS+QRRHQK++E APA P + + +VKL
Sbjct: 352 AKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKL 411
Query: 299 AKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLP 358
AK VGY +AGTVE+L + G YF+E+N RLQVEH TE + DV+L AQ+ +A G L
Sbjct: 412 AKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPL- 470
Query: 359 DLGLRQENIRI-----------------------NGCAIQCRVTTEDPARSFQPDTGRIE 395
R ++IR+ G I R+T+E+P F+P +G ++
Sbjct: 471 ---YRIKDIRMMYGVSPWGDSPIDFEDSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQ 527
Query: 396 V--FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVR 453
FRS + + A+A + DS + G++ A + M AL E +R
Sbjct: 528 ELNFRSNKNVWGYFSVAAA---GGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIR 584
Query: 454 G-VKTNIAFLQNVLNNQQFLAGTVDTQFID 482
G +T + +L +L + F +DT ++D
Sbjct: 585 GDFRTTVEYLIKLLETESFQMNRIDTGWLD 614
>gi|38679974 acetyl-Coenzyme A carboxylase alpha isoform 4 [Homo
sapiens]
Length = 2268
Score = 223 bits (569), Expect = 6e-58
Identities = 153/510 (30%), Positives = 248/510 (48%), Gaps = 73/510 (14%)
Query: 35 KPIKKVMVANRGEIAIRVFRAC---------TELGIRTVAIYSEQDT-GQMHRQKADEAY 84
K I+KV++AN G A++ R+ E IR V + + +D K + Y
Sbjct: 38 KVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHY 97
Query: 85 LIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPE 144
+ G Y ++ I+ +AK V AV G+G SE + G+ F+GP +
Sbjct: 98 VPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQ 157
Query: 145 VVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTY----------------- 187
+ +GDK+ + +A AG+P +P + + + + ++FS
Sbjct: 158 AMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVD 217
Query: 188 ---------GFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKF 238
G+P++ KA+ GGGG+G+R V++ ++ + + + A +FV +
Sbjct: 218 DGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADD----FPNLFRQVQAEVPGSPIFVMRL 273
Query: 239 IEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKL 298
++ RH+EVQIL DQYGN + L+ RDCS+QRRHQK++E APA P + + +VKL
Sbjct: 274 AKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKL 333
Query: 299 AKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLP 358
AK VGY +AGTVE+L + G YF+E+N RLQVEH TE + DV+L AQ+ +A G L
Sbjct: 334 AKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPL- 392
Query: 359 DLGLRQENIRI-----------------------NGCAIQCRVTTEDPARSFQPDTGRIE 395
R ++IR+ G I R+T+E+P F+P +G ++
Sbjct: 393 ---YRIKDIRMMYGVSPWGDSPIDFEDSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQ 449
Query: 396 V--FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVR 453
FRS + + A+A + DS + G++ A + M AL E +R
Sbjct: 450 ELNFRSNKNVWGYFSVAAA---GGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIR 506
Query: 454 G-VKTNIAFLQNVLNNQQFLAGTVDTQFID 482
G +T + +L +L + F +DT ++D
Sbjct: 507 GDFRTTVEYLIKLLETESFQMNRIDTGWLD 536
>gi|38679971 acetyl-Coenzyme A carboxylase alpha isoform 3 [Homo
sapiens]
Length = 2288
Score = 223 bits (569), Expect = 6e-58
Identities = 153/510 (30%), Positives = 248/510 (48%), Gaps = 73/510 (14%)
Query: 35 KPIKKVMVANRGEIAIRVFRAC---------TELGIRTVAIYSEQDT-GQMHRQKADEAY 84
K I+KV++AN G A++ R+ E IR V + + +D K + Y
Sbjct: 58 KVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHY 117
Query: 85 LIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPE 144
+ G Y ++ I+ +AK V AV G+G SE + G+ F+GP +
Sbjct: 118 VPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQ 177
Query: 145 VVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTY----------------- 187
+ +GDK+ + +A AG+P +P + + + + ++FS
Sbjct: 178 AMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVD 237
Query: 188 ---------GFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKF 238
G+P++ KA+ GGGG+G+R V++ ++ + + + A +FV +
Sbjct: 238 DGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADD----FPNLFRQVQAEVPGSPIFVMRL 293
Query: 239 IEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKL 298
++ RH+EVQIL DQYGN + L+ RDCS+QRRHQK++E APA P + + +VKL
Sbjct: 294 AKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKL 353
Query: 299 AKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLP 358
AK VGY +AGTVE+L + G YF+E+N RLQVEH TE + DV+L AQ+ +A G L
Sbjct: 354 AKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPL- 412
Query: 359 DLGLRQENIRI-----------------------NGCAIQCRVTTEDPARSFQPDTGRIE 395
R ++IR+ G I R+T+E+P F+P +G ++
Sbjct: 413 ---YRIKDIRMMYGVSPWGDSPIDFEDSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQ 469
Query: 396 V--FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVR 453
FRS + + A+A + DS + G++ A + M AL E +R
Sbjct: 470 ELNFRSNKNVWGYFSVAAA---GGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIR 526
Query: 454 G-VKTNIAFLQNVLNNQQFLAGTVDTQFID 482
G +T + +L +L + F +DT ++D
Sbjct: 527 GDFRTTVEYLIKLLETESFQMNRIDTGWLD 556
>gi|38679967 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo
sapiens]
Length = 2346
Score = 223 bits (569), Expect = 6e-58
Identities = 153/510 (30%), Positives = 248/510 (48%), Gaps = 73/510 (14%)
Query: 35 KPIKKVMVANRGEIAIRVFRAC---------TELGIRTVAIYSEQDT-GQMHRQKADEAY 84
K I+KV++AN G A++ R+ E IR V + + +D K + Y
Sbjct: 116 KVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHY 175
Query: 85 LIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPE 144
+ G Y ++ I+ +AK V AV G+G SE + G+ F+GP +
Sbjct: 176 VPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQ 235
Query: 145 VVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTY----------------- 187
+ +GDK+ + +A AG+P +P + + + + ++FS
Sbjct: 236 AMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVD 295
Query: 188 ---------GFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKF 238
G+P++ KA+ GGGG+G+R V++ ++ + + + A +FV +
Sbjct: 296 DGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADD----FPNLFRQVQAEVPGSPIFVMRL 351
Query: 239 IEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKL 298
++ RH+EVQIL DQYGN + L+ RDCS+QRRHQK++E APA P + + +VKL
Sbjct: 352 AKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKL 411
Query: 299 AKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLP 358
AK VGY +AGTVE+L + G YF+E+N RLQVEH TE + DV+L AQ+ +A G L
Sbjct: 412 AKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPL- 470
Query: 359 DLGLRQENIRI-----------------------NGCAIQCRVTTEDPARSFQPDTGRIE 395
R ++IR+ G I R+T+E+P F+P +G ++
Sbjct: 471 ---YRIKDIRMMYGVSPWGDSPIDFEDSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQ 527
Query: 396 V--FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVR 453
FRS + + A+A + DS + G++ A + M AL E +R
Sbjct: 528 ELNFRSNKNVWGYFSVAAA---GGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIR 584
Query: 454 G-VKTNIAFLQNVLNNQQFLAGTVDTQFID 482
G +T + +L +L + F +DT ++D
Sbjct: 585 GDFRTTVEYLIKLLETESFQMNRIDTGWLD 614
>gi|38679960 acetyl-Coenzyme A carboxylase alpha isoform 1 [Homo
sapiens]
Length = 2383
Score = 223 bits (569), Expect = 6e-58
Identities = 153/510 (30%), Positives = 248/510 (48%), Gaps = 73/510 (14%)
Query: 35 KPIKKVMVANRGEIAIRVFRAC---------TELGIRTVAIYSEQDT-GQMHRQKADEAY 84
K I+KV++AN G A++ R+ E IR V + + +D K + Y
Sbjct: 153 KVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHY 212
Query: 85 LIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPE 144
+ G Y ++ I+ +AK V AV G+G SE + G+ F+GP +
Sbjct: 213 VPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQ 272
Query: 145 VVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTY----------------- 187
+ +GDK+ + +A AG+P +P + + + + ++FS
Sbjct: 273 AMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVD 332
Query: 188 ---------GFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKF 238
G+P++ KA+ GGGG+G+R V++ ++ + + + A +FV +
Sbjct: 333 DGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADD----FPNLFRQVQAEVPGSPIFVMRL 388
Query: 239 IEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKL 298
++ RH+EVQIL DQYGN + L+ RDCS+QRRHQK++E APA P + + +VKL
Sbjct: 389 AKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKL 448
Query: 299 AKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLP 358
AK VGY +AGTVE+L + G YF+E+N RLQVEH TE + DV+L AQ+ +A G L
Sbjct: 449 AKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPL- 507
Query: 359 DLGLRQENIRI-----------------------NGCAIQCRVTTEDPARSFQPDTGRIE 395
R ++IR+ G I R+T+E+P F+P +G ++
Sbjct: 508 ---YRIKDIRMMYGVSPWGDSPIDFEDSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQ 564
Query: 396 V--FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVR 453
FRS + + A+A + DS + G++ A + M AL E +R
Sbjct: 565 ELNFRSNKNVWGYFSVAAA---GGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIR 621
Query: 454 G-VKTNIAFLQNVLNNQQFLAGTVDTQFID 482
G +T + +L +L + F +DT ++D
Sbjct: 622 GDFRTTVEYLIKLLETESFQMNRIDTGWLD 651
>gi|134142062 acetyl-Coenzyme A carboxylase beta [Homo sapiens]
Length = 2458
Score = 215 bits (548), Expect = 2e-55
Identities = 156/509 (30%), Positives = 241/509 (47%), Gaps = 74/509 (14%)
Query: 37 IKKVMVANRGEIAIRVFRAC---------TELGIRTVAIYSEQDT-GQMHRQKADEAYLI 86
I+KV++AN G A++ R+ E IR V + + +D K + Y+
Sbjct: 260 IEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVP 319
Query: 87 GRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVV 146
G Y ++ I+ +AK V AV G+G SE + GV F+GP E +
Sbjct: 320 VPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKNGVAFLGPPSEAM 379
Query: 147 RKMGDKVEARAIAIAAGVPVVPGTDAPIT---------------------------SLHE 179
+GDK+ + +A VP +P + + +T + E
Sbjct: 380 WALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGKRISVPEDVYDKGCVKDVDE 439
Query: 180 AHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFI 239
E + GFP++ KA+ GGGG+G+R S E+ + + SE +F+ K
Sbjct: 440 GLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSE----IPGSPIFLMKLA 495
Query: 240 EKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLA 299
+ RH+EVQIL DQYGN + L+ RDCSIQRRHQK+VE APA + + +++LA
Sbjct: 496 QHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEFMEQCAIRLA 555
Query: 300 KQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPD 359
K VGY +AGTVE+L + G +F+E+N RLQVEH TE I DV+L AQ+ +A G L
Sbjct: 556 KTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLH- 614
Query: 360 LGLRQENIRI-----------------------NGCAIQCRVTTEDPARSFQPDTGRIEV 396
R ++IR+ G I R+T+E+P F+P +G ++
Sbjct: 615 ---RLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDEGFKPSSGTVQE 671
Query: 397 --FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRG 454
FRS + + A+ + DS + G++ A + M AL E +RG
Sbjct: 672 LNFRSSKNVWGYFSVAAT---GGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRG 728
Query: 455 -VKTNIAFLQNVLNNQQFLAGTVDTQFID 482
+T + +L N+L + F +DT ++D
Sbjct: 729 DFRTTVEYLINLLETESFQNNDIDTGWLD 757
>gi|18105007 carbamoylphosphate synthetase 2/aspartate
transcarbamylase/dihydroorotase [Homo sapiens]
Length = 2225
Score = 78.6 bits (192), Expect = 3e-14
Identities = 91/409 (22%), Positives = 173/409 (42%), Gaps = 47/409 (11%)
Query: 36 PIKKVMVANRGEIAI-----------RVFRACTELGIRTVAIYSEQDTGQMHRQKADEAY 84
P +KV++ G ++I + +A E I+T+ I T Q + AD+ Y
Sbjct: 392 PPRKVLILGSGGLSIGQAGEFDYSGSQAIKALKEENIQTLLINPNIATVQTSQGLADKVY 451
Query: 85 LIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDA--GVRFIGPS 142
+ P+ + ++ +I+ + + V G L+ + +A A GVR +G
Sbjct: 452 FL-----PITPH-YVTQVIRNERPDGVLLTFGGQTALNCGVELTKAGVLARYGVRVLGTP 505
Query: 143 PEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTYGFPIIFKAAYGGGGR 202
E + D+ A G V P A SL +A + G+P++ +AA+ GG
Sbjct: 506 VETIELTEDRRAFAARMAEIGEHVAPSEAA--NSLEQAQAAAERLGYPVLVRAAFALGGL 563
Query: 203 GMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYE 262
G + EEL A++ + V+K ++ + IE +++ D YGN + +
Sbjct: 564 GSGFASNREELSALVAPAFAH------TSQVLVDKSLKGWKEIEYEVVRDAYGNCVTV-- 615
Query: 263 RDCSIQR------RHQKVVEIAPAAHLDPQLRTRLTSDSVKLAKQVGYENAGTVEFLVDR 316
C+++ + + +AP+ L+ + L ++K+ + +G V++ ++
Sbjct: 616 --CNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQHLGIVGECNVQYALNP 673
Query: 317 HGKHYF-IEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL------GLRQENIRI 369
+ Y+ IEVN+RL + + T L + +A G LP+L G +
Sbjct: 674 ESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRNSVTGGTAAFEPSV 733
Query: 370 NGCAIQCRVTTEDPARSFQPDTGRIEVFRS-GEGMGIRLDNASAFQGAV 417
+ C + ++ D ++ + T +S GE MGI AFQ A+
Sbjct: 734 DYCVV--KIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKAL 780
Score = 49.3 bits (116), Expect = 2e-05
Identities = 68/304 (22%), Positives = 117/304 (38%), Gaps = 30/304 (9%)
Query: 126 DFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSN 185
+ A A R +G SPE + ++ + + G+ + ++ L A +F
Sbjct: 1022 NMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRE--LSDLESARQFCQ 1079
Query: 186 TYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKPRHI 245
T G+P + + +Y G M V ++ +LE R S A A + + KFI++ + I
Sbjct: 1080 TVGYPCVVRPSYVLSGAAMNVAYTDGDLE----RFLSSAAAVSKEHPVVISKFIQEAKEI 1135
Query: 246 EVQ-ILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVK-LAKQVG 303
+V + D + + E + + P PQ T T + +K + VG
Sbjct: 1136 DVDAVASDGVVAAIAISEHVENAGVHSGDATLVTP-----PQDITAKTLERIKAIVHAVG 1190
Query: 304 YENAGTVEF---LVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360
E T F L+ + + IE N R+ + VDLV V G + +
Sbjct: 1191 QELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVEPV 1250
Query: 361 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGR-----IEVFRSGEGMGIRLDNASAFQG 415
GL + G + V + P SF G +E+ +GE G A+
Sbjct: 1251 GL------MTGSGV---VGVKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLK 1301
Query: 416 AVIS 419
A++S
Sbjct: 1302 AMLS 1305
>gi|169790915 carbamoyl-phosphate synthetase 1 isoform a precursor
[Homo sapiens]
Length = 1506
Score = 59.3 bits (142), Expect = 2e-08
Identities = 74/362 (20%), Positives = 149/362 (41%), Gaps = 38/362 (10%)
Query: 19 TSTAPAASPNVRRLEYKPIKKVMVANRGEIAI-----------RVFRACTELGIRTVAI- 66
TS P + R+E + KV++ G ++I + +A E ++TV +
Sbjct: 413 TSVLPKPALVASRVE---VSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMN 469
Query: 67 --YSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSER 124
+ T ++ ++AD Y + P+ + ++IK + + + G L+
Sbjct: 470 PNIASVQTNEVGLKQADTVYFL-----PITPQF-VTEVIKAEQPDGLILGMGGQTALNCG 523
Query: 125 ADFAQ--ACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHE 182
+ + ++ GV+ +G S E + D+ + P + S+ +A +
Sbjct: 524 VELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSF--AVESIEDALK 581
Query: 183 FSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKP 242
++T G+P++ ++AY GG G + + E L + T+A++ + VEK +
Sbjct: 582 AADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAM------TNQILVEKSVTGW 635
Query: 243 RHIEVQILGDQYGN---ILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLA 299
+ IE +++ D N + ++ D VV +APA L L S+ +
Sbjct: 636 KEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVV-VAPAQTLSNAEFQMLRRTSINVV 694
Query: 300 KQVGYENAGTVEFLVDRHGKHY-FIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLP 358
+ +G ++F + Y IEVN+RL + + T L +A G LP
Sbjct: 695 RHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLP 754
Query: 359 DL 360
++
Sbjct: 755 EI 756
>gi|21361331 carbamoyl-phosphate synthetase 1 isoform b precursor
[Homo sapiens]
Length = 1500
Score = 59.3 bits (142), Expect = 2e-08
Identities = 74/362 (20%), Positives = 149/362 (41%), Gaps = 38/362 (10%)
Query: 19 TSTAPAASPNVRRLEYKPIKKVMVANRGEIAI-----------RVFRACTELGIRTVAI- 66
TS P + R+E + KV++ G ++I + +A E ++TV +
Sbjct: 407 TSVLPKPALVASRVE---VSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMN 463
Query: 67 --YSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSER 124
+ T ++ ++AD Y + P+ + ++IK + + + G L+
Sbjct: 464 PNIASVQTNEVGLKQADTVYFL-----PITPQF-VTEVIKAEQPDGLILGMGGQTALNCG 517
Query: 125 ADFAQ--ACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHE 182
+ + ++ GV+ +G S E + D+ + P + S+ +A +
Sbjct: 518 VELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSF--AVESIEDALK 575
Query: 183 FSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKP 242
++T G+P++ ++AY GG G + + E L + T+A++ + VEK +
Sbjct: 576 AADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAM------TNQILVEKSVTGW 629
Query: 243 RHIEVQILGDQYGN---ILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLA 299
+ IE +++ D N + ++ D VV +APA L L S+ +
Sbjct: 630 KEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVV-VAPAQTLSNAEFQMLRRTSINVV 688
Query: 300 KQVGYENAGTVEFLVDRHGKHY-FIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLP 358
+ +G ++F + Y IEVN+RL + + T L +A G LP
Sbjct: 689 RHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLP 748
Query: 359 DL 360
++
Sbjct: 749 EI 750
>gi|170295797 carbamoyl-phosphate synthetase 1 isoform c [Homo
sapiens]
Length = 1049
Score = 56.2 bits (134), Expect = 2e-07
Identities = 52/233 (22%), Positives = 99/233 (42%), Gaps = 13/233 (5%)
Query: 132 QDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTYGFPI 191
++ GV+ +G S E + D+ + P + S+ +A + ++T G+P+
Sbjct: 76 KEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSF--AVESIEDALKAADTIGYPV 133
Query: 192 IFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILG 251
+ ++AY GG G + + E L + T+A++ + VEK + + IE +++
Sbjct: 134 MIRSAYALGGLGSGICPNRETLMDLSTKAFAM------TNQILVEKSVTGWKEIEYEVVR 187
Query: 252 DQYGN---ILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAKQVGYENAG 308
D N + ++ D VV +APA L L S+ + + +G
Sbjct: 188 DADDNCVTVCNMENVDAMGVHTGDSVV-VAPAQTLSNAEFQMLRRTSINVVRHLGIVGEC 246
Query: 309 TVEFLVDRHGKHY-FIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360
++F + Y IEVN+RL + + T L +A G LP++
Sbjct: 247 NIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEI 299
>gi|109150422 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like
1 isoform b [Homo sapiens]
Length = 340
Score = 47.4 bits (111), Expect = 8e-05
Identities = 43/174 (24%), Positives = 69/174 (39%), Gaps = 27/174 (15%)
Query: 696 AGGVVEAAIS--YTGDVADPSRTKYSLQYYMGLAEELVRAGTHILCIKDMAGLLKPTACT 753
A G V A+ Y G + T+ S + Y G + + + D G+ P +
Sbjct: 179 ARGYVSCALGCPYEGSITPQKVTEVSKRLY--------GMGCYEISLGDTIGVGTPGSMK 230
Query: 754 MLVSSLRDRFPDLPLHIHTHDTSGAGVAAMLACAQAGADVVDVAADSM------SGMTSQ 807
++ S+ P L +H HDT G +A +L Q G +VVD A + G +
Sbjct: 231 RMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGN 290
Query: 808 PSMGALVACTRGTPLDTEVPMERVFDYSEYWEGARGLYAAFDCTATMKSGNSDV 861
+ L+ G L+T V + +V + + F C A K+ NS V
Sbjct: 291 VATEDLIYMLNGLGLNTGVNLYKVMEAGD-----------FICKAVNKTTNSKV 333
>gi|109150427 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like
1 isoform a [Homo sapiens]
Length = 370
Score = 47.4 bits (111), Expect = 8e-05
Identities = 43/174 (24%), Positives = 69/174 (39%), Gaps = 27/174 (15%)
Query: 696 AGGVVEAAIS--YTGDVADPSRTKYSLQYYMGLAEELVRAGTHILCIKDMAGLLKPTACT 753
A G V A+ Y G + T+ S + Y G + + + D G+ P +
Sbjct: 209 ARGYVSCALGCPYEGSITPQKVTEVSKRLY--------GMGCYEISLGDTIGVGTPGSMK 260
Query: 754 MLVSSLRDRFPDLPLHIHTHDTSGAGVAAMLACAQAGADVVDVAADSM------SGMTSQ 807
++ S+ P L +H HDT G +A +L Q G +VVD A + G +
Sbjct: 261 RMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGN 320
Query: 808 PSMGALVACTRGTPLDTEVPMERVFDYSEYWEGARGLYAAFDCTATMKSGNSDV 861
+ L+ G L+T V + +V + + F C A K+ NS V
Sbjct: 321 VATEDLIYMLNGLGLNTGVNLYKVMEAGD-----------FICKAVNKTTNSKV 363
>gi|62198232 3-hydroxy-3-methylglutaryl CoA lyase [Homo sapiens]
Length = 325
Score = 39.3 bits (90), Expect = 0.022
Identities = 36/154 (23%), Positives = 64/154 (41%), Gaps = 8/154 (5%)
Query: 690 MEAAGSAGGVVEAAISYTGDVADPSRTKYSLQYYMGLAEELVRAGTHILCIKDMAGLLKP 749
++AA SA V +S + P K S + ++ G + + + D G+ P
Sbjct: 154 LKAAQSANISVRGYVSCA--LGCPYEGKISPAKVAEVTKKFYSMGCYEISLGDTIGVGTP 211
Query: 750 TACTMLVSSLRDRFPDLPLHIHTHDTSGAGVAAMLACAQAGADVVDVAADSMSGMT-SQP 808
++S++ P L +H HDT G +A L Q G VVD + + G +Q
Sbjct: 212 GIMKDMLSAVMQEVPLAALAVHCHDTYGQALANTLMALQMGVSVVDSSVAGLGGCPYAQG 271
Query: 809 SMG-----ALVACTRGTPLDTEVPMERVFDYSEY 837
+ G LV G + T V ++++ + +
Sbjct: 272 ASGNLATEDLVYMLEGLGIHTGVNLQKLLEAGNF 305
>gi|219802034 nuclear factor related to kappaB binding protein
isoform 1 [Homo sapiens]
Length = 1299
Score = 37.0 bits (84), Expect = 0.11
Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 9/57 (15%)
Query: 512 PTTPIPVKASPSPTDPVVPAVPIGPPPAGFRDILLREGPEGFARAVRNHPGLLLMDT 568
P TP+ +PT P +PA+PI PPP + + GP + ++ G+LL+ +
Sbjct: 719 PVTPV------TPTTPALPAIPISPPPV---SAVNKSGPSTVSEPAKSSSGVLLVSS 766
>gi|23346420 nuclear factor related to kappaB binding protein
isoform 2 [Homo sapiens]
Length = 1324
Score = 37.0 bits (84), Expect = 0.11
Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 9/57 (15%)
Query: 512 PTTPIPVKASPSPTDPVVPAVPIGPPPAGFRDILLREGPEGFARAVRNHPGLLLMDT 568
P TP+ +PT P +PA+PI PPP + + GP + ++ G+LL+ +
Sbjct: 744 PVTPV------TPTTPALPAIPISPPPV---SAVNKSGPSTVSEPAKSSSGVLLVSS 791
>gi|115387123 protocadherin 15 isoform CD1-4 precursor [Homo sapiens]
Length = 1955
Score = 32.3 bits (72), Expect = 2.7
Identities = 13/33 (39%), Positives = 19/33 (57%)
Query: 507 VMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPA 539
V +GP TP + P+P P P++P PPP+
Sbjct: 1800 VSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPS 1832
>gi|218505798 protocadherin 15 isoform CD1-10 precursor [Homo sapiens]
Length = 1932
Score = 32.3 bits (72), Expect = 2.7
Identities = 13/33 (39%), Positives = 19/33 (57%)
Query: 507 VMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPA 539
V +GP TP + P+P P P++P PPP+
Sbjct: 1777 VSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPS 1809
>gi|218505785 protocadherin 15 isoform CD1-9 precursor [Homo sapiens]
Length = 1935
Score = 32.3 bits (72), Expect = 2.7
Identities = 13/33 (39%), Positives = 19/33 (57%)
Query: 507 VMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPA 539
V +GP TP + P+P P P++P PPP+
Sbjct: 1780 VSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPS 1812
>gi|218505783 protocadherin 15 isoform CD1-8 precursor [Homo sapiens]
Length = 1915
Score = 32.3 bits (72), Expect = 2.7
Identities = 13/33 (39%), Positives = 19/33 (57%)
Query: 507 VMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPA 539
V +GP TP + P+P P P++P PPP+
Sbjct: 1760 VSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPS 1792
>gi|218505781 protocadherin 15 isoform CD1-7 precursor [Homo sapiens]
Length = 1952
Score = 32.3 bits (72), Expect = 2.7
Identities = 13/33 (39%), Positives = 19/33 (57%)
Query: 507 VMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPA 539
V +GP TP + P+P P P++P PPP+
Sbjct: 1797 VSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPS 1829
>gi|218505779 protocadherin 15 isoform CD1-6 precursor [Homo sapiens]
Length = 1886
Score = 32.3 bits (72), Expect = 2.7
Identities = 13/33 (39%), Positives = 19/33 (57%)
Query: 507 VMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPA 539
V +GP TP + P+P P P++P PPP+
Sbjct: 1731 VSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPS 1763
>gi|218505777 protocadherin 15 isoform CD1-2 precursor [Homo sapiens]
Length = 1957
Score = 32.3 bits (72), Expect = 2.7
Identities = 13/33 (39%), Positives = 19/33 (57%)
Query: 507 VMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPA 539
V +GP TP + P+P P P++P PPP+
Sbjct: 1802 VSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPS 1834
>gi|218505775 protocadherin 15 isoform CD1-1 precursor [Homo sapiens]
Length = 1962
Score = 32.3 bits (72), Expect = 2.7
Identities = 13/33 (39%), Positives = 19/33 (57%)
Query: 507 VMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPA 539
V +GP TP + P+P P P++P PPP+
Sbjct: 1807 VSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPS 1839
>gi|53759113 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 2
[Homo sapiens]
Length = 372
Score = 31.6 bits (70), Expect = 4.7
Identities = 16/46 (34%), Positives = 22/46 (47%)
Query: 520 ASPSPTDPVVPAVPIGPPPAGFRDILLREGPEGFARAVRNHPGLLL 565
A P PT P +P P PP R ++ P R R +PG+L+
Sbjct: 85 ALPGPTAPTLPPCPDSPPGLVGRLLIEFTSPMPLERVQRENPGVLM 130
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,171,993
Number of Sequences: 37866
Number of extensions: 2087881
Number of successful extensions: 7155
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 7020
Number of HSP's gapped (non-prelim): 103
length of query: 1178
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1065
effective length of database: 13,968,660
effective search space: 14876622900
effective search space used: 14876622900
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.