BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|106049292 pyruvate carboxylase precursor [Homo sapiens] (1178 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|106049528 pyruvate carboxylase precursor [Homo sapiens] 2349 0.0 gi|106049295 pyruvate carboxylase precursor [Homo sapiens] 2349 0.0 gi|106049292 pyruvate carboxylase precursor [Homo sapiens] 2349 0.0 gi|65506442 propionyl-Coenzyme A carboxylase, alpha polypeptide ... 377 e-104 gi|189095269 propionyl-Coenzyme A carboxylase, alpha polypeptide... 377 e-104 gi|116805327 methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) pr... 377 e-104 gi|38679977 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo ... 223 6e-58 gi|38679974 acetyl-Coenzyme A carboxylase alpha isoform 4 [Homo ... 223 6e-58 gi|38679971 acetyl-Coenzyme A carboxylase alpha isoform 3 [Homo ... 223 6e-58 gi|38679967 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo ... 223 6e-58 gi|38679960 acetyl-Coenzyme A carboxylase alpha isoform 1 [Homo ... 223 6e-58 gi|134142062 acetyl-Coenzyme A carboxylase beta [Homo sapiens] 215 2e-55 gi|18105007 carbamoylphosphate synthetase 2/aspartate transcarba... 79 3e-14 gi|169790915 carbamoyl-phosphate synthetase 1 isoform a precurso... 59 2e-08 gi|21361331 carbamoyl-phosphate synthetase 1 isoform b precursor... 59 2e-08 gi|170295797 carbamoyl-phosphate synthetase 1 isoform c [Homo sa... 56 2e-07 gi|109150422 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-l... 47 8e-05 gi|109150427 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-l... 47 8e-05 gi|62198232 3-hydroxy-3-methylglutaryl CoA lyase [Homo sapiens] 39 0.022 gi|219802034 nuclear factor related to kappaB binding protein is... 37 0.11 gi|23346420 nuclear factor related to kappaB binding protein iso... 37 0.11 gi|115387123 protocadherin 15 isoform CD1-4 precursor [Homo sapi... 32 2.7 gi|218505798 protocadherin 15 isoform CD1-10 precursor [Homo sap... 32 2.7 gi|218505785 protocadherin 15 isoform CD1-9 precursor [Homo sapi... 32 2.7 gi|218505783 protocadherin 15 isoform CD1-8 precursor [Homo sapi... 32 2.7 gi|218505781 protocadherin 15 isoform CD1-7 precursor [Homo sapi... 32 2.7 gi|218505779 protocadherin 15 isoform CD1-6 precursor [Homo sapi... 32 2.7 gi|218505777 protocadherin 15 isoform CD1-2 precursor [Homo sapi... 32 2.7 gi|218505775 protocadherin 15 isoform CD1-1 precursor [Homo sapi... 32 2.7 gi|53759113 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 2... 32 4.7 >gi|106049528 pyruvate carboxylase precursor [Homo sapiens] Length = 1178 Score = 2349 bits (6087), Expect = 0.0 Identities = 1178/1178 (100%), Positives = 1178/1178 (100%) Query: 1 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG 60 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG Sbjct: 1 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG 60 Query: 61 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF 120 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF Sbjct: 61 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF 120 Query: 121 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA 180 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA Sbjct: 121 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA 180 Query: 181 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE 240 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE Sbjct: 181 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE 240 Query: 241 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK 300 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK Sbjct: 241 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK 300 Query: 301 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL Sbjct: 301 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360 Query: 361 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP 420 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP Sbjct: 361 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP 420 Query: 421 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF 480 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF Sbjct: 421 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF 480 Query: 481 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG 540 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG Sbjct: 481 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG 540 Query: 541 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK 600 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK Sbjct: 541 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK 600 Query: 601 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF 660 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF Sbjct: 601 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF 660 Query: 661 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL 720 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL Sbjct: 661 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL 720 Query: 721 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV 780 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV Sbjct: 721 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV 780 Query: 781 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG 840 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG Sbjct: 781 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG 840 Query: 841 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM 900 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM Sbjct: 841 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM 900 Query: 901 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP 960 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP Sbjct: 901 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP 960 Query: 961 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF 1020 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF Sbjct: 961 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF 1020 Query: 1021 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL 1080 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL Sbjct: 1021 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL 1080 Query: 1081 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL 1140 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL Sbjct: 1081 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL 1140 Query: 1141 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE 1178 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE Sbjct: 1141 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE 1178 >gi|106049295 pyruvate carboxylase precursor [Homo sapiens] Length = 1178 Score = 2349 bits (6087), Expect = 0.0 Identities = 1178/1178 (100%), Positives = 1178/1178 (100%) Query: 1 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG 60 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG Sbjct: 1 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG 60 Query: 61 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF 120 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF Sbjct: 61 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF 120 Query: 121 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA 180 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA Sbjct: 121 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA 180 Query: 181 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE 240 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE Sbjct: 181 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE 240 Query: 241 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK 300 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK Sbjct: 241 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK 300 Query: 301 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL Sbjct: 301 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360 Query: 361 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP 420 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP Sbjct: 361 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP 420 Query: 421 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF 480 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF Sbjct: 421 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF 480 Query: 481 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG 540 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG Sbjct: 481 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG 540 Query: 541 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK 600 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK Sbjct: 541 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK 600 Query: 601 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF 660 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF Sbjct: 601 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF 660 Query: 661 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL 720 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL Sbjct: 661 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL 720 Query: 721 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV 780 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV Sbjct: 721 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV 780 Query: 781 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG 840 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG Sbjct: 781 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG 840 Query: 841 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM 900 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM Sbjct: 841 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM 900 Query: 901 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP 960 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP Sbjct: 901 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP 960 Query: 961 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF 1020 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF Sbjct: 961 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF 1020 Query: 1021 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL 1080 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL Sbjct: 1021 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL 1080 Query: 1081 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL 1140 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL Sbjct: 1081 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL 1140 Query: 1141 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE 1178 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE Sbjct: 1141 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE 1178 >gi|106049292 pyruvate carboxylase precursor [Homo sapiens] Length = 1178 Score = 2349 bits (6087), Expect = 0.0 Identities = 1178/1178 (100%), Positives = 1178/1178 (100%) Query: 1 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG 60 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG Sbjct: 1 MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG 60 Query: 61 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF 120 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF Sbjct: 61 IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF 120 Query: 121 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA 180 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA Sbjct: 121 LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA 180 Query: 181 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE 240 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE Sbjct: 181 HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE 240 Query: 241 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK 300 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK Sbjct: 241 KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK 300 Query: 301 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL Sbjct: 301 QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360 Query: 361 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP 420 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP Sbjct: 361 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP 420 Query: 421 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF 480 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF Sbjct: 421 HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF 480 Query: 481 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG 540 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG Sbjct: 481 IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG 540 Query: 541 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK 600 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK Sbjct: 541 FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK 600 Query: 601 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF 660 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF Sbjct: 601 LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF 660 Query: 661 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL 720 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL Sbjct: 661 KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL 720 Query: 721 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV 780 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV Sbjct: 721 QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV 780 Query: 781 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG 840 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG Sbjct: 781 AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG 840 Query: 841 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM 900 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM Sbjct: 841 ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM 900 Query: 901 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP 960 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP Sbjct: 901 LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP 960 Query: 961 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF 1020 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF Sbjct: 961 EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF 1020 Query: 1021 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL 1080 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL Sbjct: 1021 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL 1080 Query: 1081 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL 1140 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL Sbjct: 1081 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL 1140 Query: 1141 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE 1178 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE Sbjct: 1141 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE 1178 >gi|65506442 propionyl-Coenzyme A carboxylase, alpha polypeptide isoform a precursor [Homo sapiens] Length = 728 Score = 377 bits (969), Expect = e-104 Identities = 202/452 (44%), Positives = 291/452 (64%), Gaps = 9/452 (1%) Query: 35 KPIKKVMVANRGEIAIRVFRACTELGIRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPV- 93 K K++VANRGEIA RV R C ++GI+TVAI+S+ D +H + ADEA +G AP Sbjct: 61 KTFDKILVANRGEIACRVIRTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGP--APTS 118 Query: 94 QAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVVRKMGDKV 153 ++YL++ I++ K+ AVHPGYGFLSE +FA+ V FIGP ++ MGDK+ Sbjct: 119 KSYLNMDAIMEAIKKTRAQAVHPGYGFLSENKEFARCLAAEDVVFIGPDTHAIQAMGDKI 178 Query: 154 EARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEEL 213 E++ +A A V +PG D + EA + G+P++ KA+ GGGG+GMR+ EE Sbjct: 179 ESKLLAKKAEVNTIPGFDGVVKDAEEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEET 238 Query: 214 EENYTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQK 273 + + + EA ++FG+ L +EKFI+ PRHIE+Q+LGD++GN L L ER+CSIQRR+QK Sbjct: 239 RDGFRLSSQEAASSFGDDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQK 298 Query: 274 VVEIAPAAHLDPQLRTRLTSDSVKLAKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEH 333 VVE AP+ LD + R + +V LA+ V Y +AGTVEFLVD YF+E+N+RLQVEH Sbjct: 299 VVEEAPSIFLDAETRRAMGEQAVALARAVKYSSAGTVEFLVDSKKNFYFLEMNTRLQVEH 358 Query: 334 TVTEEITDVDLVHAQIHVAEGRSLPDLGLRQENIRINGCAIQCRVTTEDPARSF-QPDTG 392 VTE IT +DLV I VA+G L +Q +IRING A++CRV EDP +SF P G Sbjct: 359 PVTECITGLDLVQEMIRVAKGYPLRH---KQADIRINGWAVECRVYAEDPYKSFGLPSIG 415 Query: 393 RIEVFRSGEGM-GIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFR 451 R+ ++ + G+R+D+ G+ IS +YD ++ K+I +G D A +M+ AL + Sbjct: 416 RLSQYQEPLHLPGVRVDSGIQ-PGSDISIYYDPMISKLITYGSDRTEALKRMADALDNYV 474 Query: 452 VRGVKTNIAFLQNVLNNQQFLAGTVDTQFIDE 483 +RGV NIA L+ V+ N +F+ G + T+F+ + Sbjct: 475 IRGVTHNIALLREVIINSRFVKGDISTKFLSD 506 Score = 62.8 bits (151), Expect = 2e-09 Identities = 30/76 (39%), Positives = 46/76 (60%) Query: 1103 KALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVLSAMKMETVVTSPMEGTVRKVHV 1162 K +D + +PMPG V+ + V G VA+GQ +CV+ AMKM+ +T+ GTV+ VH Sbjct: 653 KVTEDTSSVLRSPMPGVVVAVSVKPGDAVAEGQEICVIEAMKMQNSMTAGKTGTVKSVHC 712 Query: 1163 TKDMTLEGDDLILEIE 1178 T+ DL++E+E Sbjct: 713 QAGDTVGEGDLLVELE 728 >gi|189095269 propionyl-Coenzyme A carboxylase, alpha polypeptide isoform b [Homo sapiens] Length = 702 Score = 377 bits (969), Expect = e-104 Identities = 202/452 (44%), Positives = 291/452 (64%), Gaps = 9/452 (1%) Query: 35 KPIKKVMVANRGEIAIRVFRACTELGIRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPV- 93 K K++VANRGEIA RV R C ++GI+TVAI+S+ D +H + ADEA +G AP Sbjct: 35 KTFDKILVANRGEIACRVIRTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGP--APTS 92 Query: 94 QAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVVRKMGDKV 153 ++YL++ I++ K+ AVHPGYGFLSE +FA+ V FIGP ++ MGDK+ Sbjct: 93 KSYLNMDAIMEAIKKTRAQAVHPGYGFLSENKEFARCLAAEDVVFIGPDTHAIQAMGDKI 152 Query: 154 EARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEEL 213 E++ +A A V +PG D + EA + G+P++ KA+ GGGG+GMR+ EE Sbjct: 153 ESKLLAKKAEVNTIPGFDGVVKDAEEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEET 212 Query: 214 EENYTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQK 273 + + + EA ++FG+ L +EKFI+ PRHIE+Q+LGD++GN L L ER+CSIQRR+QK Sbjct: 213 RDGFRLSSQEAASSFGDDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQK 272 Query: 274 VVEIAPAAHLDPQLRTRLTSDSVKLAKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEH 333 VVE AP+ LD + R + +V LA+ V Y +AGTVEFLVD YF+E+N+RLQVEH Sbjct: 273 VVEEAPSIFLDAETRRAMGEQAVALARAVKYSSAGTVEFLVDSKKNFYFLEMNTRLQVEH 332 Query: 334 TVTEEITDVDLVHAQIHVAEGRSLPDLGLRQENIRINGCAIQCRVTTEDPARSF-QPDTG 392 VTE IT +DLV I VA+G L +Q +IRING A++CRV EDP +SF P G Sbjct: 333 PVTECITGLDLVQEMIRVAKGYPLRH---KQADIRINGWAVECRVYAEDPYKSFGLPSIG 389 Query: 393 RIEVFRSGEGM-GIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFR 451 R+ ++ + G+R+D+ G+ IS +YD ++ K+I +G D A +M+ AL + Sbjct: 390 RLSQYQEPLHLPGVRVDSGIQ-PGSDISIYYDPMISKLITYGSDRTEALKRMADALDNYV 448 Query: 452 VRGVKTNIAFLQNVLNNQQFLAGTVDTQFIDE 483 +RGV NIA L+ V+ N +F+ G + T+F+ + Sbjct: 449 IRGVTHNIALLREVIINSRFVKGDISTKFLSD 480 Score = 62.8 bits (151), Expect = 2e-09 Identities = 30/76 (39%), Positives = 46/76 (60%) Query: 1103 KALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVLSAMKMETVVTSPMEGTVRKVHV 1162 K +D + +PMPG V+ + V G VA+GQ +CV+ AMKM+ +T+ GTV+ VH Sbjct: 627 KVTEDTSSVLRSPMPGVVVAVSVKPGDAVAEGQEICVIEAMKMQNSMTAGKTGTVKSVHC 686 Query: 1163 TKDMTLEGDDLILEIE 1178 T+ DL++E+E Sbjct: 687 QAGDTVGEGDLLVELE 702 >gi|116805327 methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) precursor [Homo sapiens] Length = 725 Score = 377 bits (967), Expect = e-104 Identities = 214/540 (39%), Positives = 308/540 (57%), Gaps = 9/540 (1%) Query: 37 IKKVMVANRGEIAIRVFRACTELGIRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAY 96 I KV++ANRGEIA RV R +LG++TVA+YSE D MH ADEAY IG + Q+Y Sbjct: 49 ITKVLIANRGEIACRVMRTAKKLGVQTVAVYSEADRNSMHVDMADEAYSIGPAPSQ-QSY 107 Query: 97 LHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEAR 156 L + II+VAK + A+HPG GFLSE +FA+ C+ G+ FIGP P +R MG K ++ Sbjct: 108 LSMEKIIQVAKTSAAQAIHPGCGFLSENMEFAELCKQEGIIFIGPPPSAIRDMGIKSTSK 167 Query: 157 AIAIAAGVPVVPGTDAPITSLHEAHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEEN 216 +I AAGVPVV G S E + G+P++ KA GGGG+GMR+V S +E +E Sbjct: 168 SIMAAAGVPVVEGYHGEDQSDQCLKEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQ 227 Query: 217 YTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVE 276 A EA +F + A+ +EKF++ PRH+EVQ+ GD +GN ++L+ERDCS+QRRHQK++E Sbjct: 228 LESARREAKKSFNDDAMLIEKFVDTPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIE 287 Query: 277 IAPAAHLDPQLRTRLTSDSVKLAKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVT 336 APA + ++R +L +V+ AK V Y AGTVEF++D F+E+N+RLQVEH VT Sbjct: 288 EAPAPGIKSEVRKKLGEAAVRAAKAVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVT 347 Query: 337 EEITDVDLVHAQIHVAEGRSLPDLGLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEV 396 E IT DLV Q+ +A G +P L QE I + G A + R+ EDP+ +F P G + Sbjct: 348 EMITGTDLVEWQLRIAAGEKIP---LSQEEITLQGHAFEARIYAEDPSNNFMPVAGPLVH 404 Query: 397 FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVK 456 + QG +S HYD ++ K++ D A TK+ +L ++ + G+ Sbjct: 405 LSTPRADPSTRIETGVRQGDEVSVHYDPMIAKLVVWAADRQAALTKLRYSLRQYNIVGLH 464 Query: 457 TNIAFLQNVLNNQQFLAGTVDTQFIDE-NPELFQLRPAQNRAQKLLHYLGHVMVNGPTTP 515 TNI FL N+ + +F AG V T FI + + +L R A + LG ++ T Sbjct: 465 TNIDFLLNLSGHPEFEAGNVHTDFIPQHHKQLLLSRKAAAKESLCQAALGLILKEKAMTD 524 Query: 516 IPVKASPSPTDPVVPAVPIGPPPAGFRDILLREGPEGFARAVR-NHPG---LLLMDTTFR 571 + P + + R++ L++G A AV NH G + + D TF+ Sbjct: 525 TFTLQAHDQFSPFSSSSGRRLNISYTRNMTLKDGKNNVAIAVTYNHDGSYSMQIEDKTFQ 584 Score = 47.8 bits (112), Expect = 6e-05 Identities = 29/64 (45%), Positives = 35/64 (54%), Gaps = 5/64 (7%) Query: 1102 PKALKDVKGQIG-----APMPGKVIDIKVVAGAKVAKGQPLCVLSAMKMETVVTSPMEGT 1156 PK L V Q APM G + + V AG KV G L V+ AMKME + SP +GT Sbjct: 634 PKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDGT 693 Query: 1157 VRKV 1160 V+KV Sbjct: 694 VKKV 697 >gi|38679977 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo sapiens] Length = 2346 Score = 223 bits (569), Expect = 6e-58 Identities = 153/510 (30%), Positives = 248/510 (48%), Gaps = 73/510 (14%) Query: 35 KPIKKVMVANRGEIAIRVFRAC---------TELGIRTVAIYSEQDT-GQMHRQKADEAY 84 K I+KV++AN G A++ R+ E IR V + + +D K + Y Sbjct: 116 KVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHY 175 Query: 85 LIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPE 144 + G Y ++ I+ +AK V AV G+G SE + G+ F+GP + Sbjct: 176 VPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQ 235 Query: 145 VVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTY----------------- 187 + +GDK+ + +A AG+P +P + + + + ++FS Sbjct: 236 AMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVD 295 Query: 188 ---------GFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKF 238 G+P++ KA+ GGGG+G+R V++ ++ + + + A +FV + Sbjct: 296 DGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADD----FPNLFRQVQAEVPGSPIFVMRL 351 Query: 239 IEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKL 298 ++ RH+EVQIL DQYGN + L+ RDCS+QRRHQK++E APA P + + +VKL Sbjct: 352 AKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKL 411 Query: 299 AKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLP 358 AK VGY +AGTVE+L + G YF+E+N RLQVEH TE + DV+L AQ+ +A G L Sbjct: 412 AKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPL- 470 Query: 359 DLGLRQENIRI-----------------------NGCAIQCRVTTEDPARSFQPDTGRIE 395 R ++IR+ G I R+T+E+P F+P +G ++ Sbjct: 471 ---YRIKDIRMMYGVSPWGDSPIDFEDSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQ 527 Query: 396 V--FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVR 453 FRS + + A+A + DS + G++ A + M AL E +R Sbjct: 528 ELNFRSNKNVWGYFSVAAA---GGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIR 584 Query: 454 G-VKTNIAFLQNVLNNQQFLAGTVDTQFID 482 G +T + +L +L + F +DT ++D Sbjct: 585 GDFRTTVEYLIKLLETESFQMNRIDTGWLD 614 >gi|38679974 acetyl-Coenzyme A carboxylase alpha isoform 4 [Homo sapiens] Length = 2268 Score = 223 bits (569), Expect = 6e-58 Identities = 153/510 (30%), Positives = 248/510 (48%), Gaps = 73/510 (14%) Query: 35 KPIKKVMVANRGEIAIRVFRAC---------TELGIRTVAIYSEQDT-GQMHRQKADEAY 84 K I+KV++AN G A++ R+ E IR V + + +D K + Y Sbjct: 38 KVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHY 97 Query: 85 LIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPE 144 + G Y ++ I+ +AK V AV G+G SE + G+ F+GP + Sbjct: 98 VPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQ 157 Query: 145 VVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTY----------------- 187 + +GDK+ + +A AG+P +P + + + + ++FS Sbjct: 158 AMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVD 217 Query: 188 ---------GFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKF 238 G+P++ KA+ GGGG+G+R V++ ++ + + + A +FV + Sbjct: 218 DGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADD----FPNLFRQVQAEVPGSPIFVMRL 273 Query: 239 IEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKL 298 ++ RH+EVQIL DQYGN + L+ RDCS+QRRHQK++E APA P + + +VKL Sbjct: 274 AKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKL 333 Query: 299 AKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLP 358 AK VGY +AGTVE+L + G YF+E+N RLQVEH TE + DV+L AQ+ +A G L Sbjct: 334 AKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPL- 392 Query: 359 DLGLRQENIRI-----------------------NGCAIQCRVTTEDPARSFQPDTGRIE 395 R ++IR+ G I R+T+E+P F+P +G ++ Sbjct: 393 ---YRIKDIRMMYGVSPWGDSPIDFEDSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQ 449 Query: 396 V--FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVR 453 FRS + + A+A + DS + G++ A + M AL E +R Sbjct: 450 ELNFRSNKNVWGYFSVAAA---GGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIR 506 Query: 454 G-VKTNIAFLQNVLNNQQFLAGTVDTQFID 482 G +T + +L +L + F +DT ++D Sbjct: 507 GDFRTTVEYLIKLLETESFQMNRIDTGWLD 536 >gi|38679971 acetyl-Coenzyme A carboxylase alpha isoform 3 [Homo sapiens] Length = 2288 Score = 223 bits (569), Expect = 6e-58 Identities = 153/510 (30%), Positives = 248/510 (48%), Gaps = 73/510 (14%) Query: 35 KPIKKVMVANRGEIAIRVFRAC---------TELGIRTVAIYSEQDT-GQMHRQKADEAY 84 K I+KV++AN G A++ R+ E IR V + + +D K + Y Sbjct: 58 KVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHY 117 Query: 85 LIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPE 144 + G Y ++ I+ +AK V AV G+G SE + G+ F+GP + Sbjct: 118 VPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQ 177 Query: 145 VVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTY----------------- 187 + +GDK+ + +A AG+P +P + + + + ++FS Sbjct: 178 AMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVD 237 Query: 188 ---------GFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKF 238 G+P++ KA+ GGGG+G+R V++ ++ + + + A +FV + Sbjct: 238 DGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADD----FPNLFRQVQAEVPGSPIFVMRL 293 Query: 239 IEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKL 298 ++ RH+EVQIL DQYGN + L+ RDCS+QRRHQK++E APA P + + +VKL Sbjct: 294 AKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKL 353 Query: 299 AKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLP 358 AK VGY +AGTVE+L + G YF+E+N RLQVEH TE + DV+L AQ+ +A G L Sbjct: 354 AKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPL- 412 Query: 359 DLGLRQENIRI-----------------------NGCAIQCRVTTEDPARSFQPDTGRIE 395 R ++IR+ G I R+T+E+P F+P +G ++ Sbjct: 413 ---YRIKDIRMMYGVSPWGDSPIDFEDSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQ 469 Query: 396 V--FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVR 453 FRS + + A+A + DS + G++ A + M AL E +R Sbjct: 470 ELNFRSNKNVWGYFSVAAA---GGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIR 526 Query: 454 G-VKTNIAFLQNVLNNQQFLAGTVDTQFID 482 G +T + +L +L + F +DT ++D Sbjct: 527 GDFRTTVEYLIKLLETESFQMNRIDTGWLD 556 >gi|38679967 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo sapiens] Length = 2346 Score = 223 bits (569), Expect = 6e-58 Identities = 153/510 (30%), Positives = 248/510 (48%), Gaps = 73/510 (14%) Query: 35 KPIKKVMVANRGEIAIRVFRAC---------TELGIRTVAIYSEQDT-GQMHRQKADEAY 84 K I+KV++AN G A++ R+ E IR V + + +D K + Y Sbjct: 116 KVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHY 175 Query: 85 LIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPE 144 + G Y ++ I+ +AK V AV G+G SE + G+ F+GP + Sbjct: 176 VPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQ 235 Query: 145 VVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTY----------------- 187 + +GDK+ + +A AG+P +P + + + + ++FS Sbjct: 236 AMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVD 295 Query: 188 ---------GFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKF 238 G+P++ KA+ GGGG+G+R V++ ++ + + + A +FV + Sbjct: 296 DGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADD----FPNLFRQVQAEVPGSPIFVMRL 351 Query: 239 IEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKL 298 ++ RH+EVQIL DQYGN + L+ RDCS+QRRHQK++E APA P + + +VKL Sbjct: 352 AKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKL 411 Query: 299 AKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLP 358 AK VGY +AGTVE+L + G YF+E+N RLQVEH TE + DV+L AQ+ +A G L Sbjct: 412 AKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPL- 470 Query: 359 DLGLRQENIRI-----------------------NGCAIQCRVTTEDPARSFQPDTGRIE 395 R ++IR+ G I R+T+E+P F+P +G ++ Sbjct: 471 ---YRIKDIRMMYGVSPWGDSPIDFEDSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQ 527 Query: 396 V--FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVR 453 FRS + + A+A + DS + G++ A + M AL E +R Sbjct: 528 ELNFRSNKNVWGYFSVAAA---GGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIR 584 Query: 454 G-VKTNIAFLQNVLNNQQFLAGTVDTQFID 482 G +T + +L +L + F +DT ++D Sbjct: 585 GDFRTTVEYLIKLLETESFQMNRIDTGWLD 614 >gi|38679960 acetyl-Coenzyme A carboxylase alpha isoform 1 [Homo sapiens] Length = 2383 Score = 223 bits (569), Expect = 6e-58 Identities = 153/510 (30%), Positives = 248/510 (48%), Gaps = 73/510 (14%) Query: 35 KPIKKVMVANRGEIAIRVFRAC---------TELGIRTVAIYSEQDT-GQMHRQKADEAY 84 K I+KV++AN G A++ R+ E IR V + + +D K + Y Sbjct: 153 KVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHY 212 Query: 85 LIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPE 144 + G Y ++ I+ +AK V AV G+G SE + G+ F+GP + Sbjct: 213 VPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQ 272 Query: 145 VVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTY----------------- 187 + +GDK+ + +A AG+P +P + + + + ++FS Sbjct: 273 AMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVD 332 Query: 188 ---------GFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKF 238 G+P++ KA+ GGGG+G+R V++ ++ + + + A +FV + Sbjct: 333 DGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADD----FPNLFRQVQAEVPGSPIFVMRL 388 Query: 239 IEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKL 298 ++ RH+EVQIL DQYGN + L+ RDCS+QRRHQK++E APA P + + +VKL Sbjct: 389 AKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKL 448 Query: 299 AKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLP 358 AK VGY +AGTVE+L + G YF+E+N RLQVEH TE + DV+L AQ+ +A G L Sbjct: 449 AKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPL- 507 Query: 359 DLGLRQENIRI-----------------------NGCAIQCRVTTEDPARSFQPDTGRIE 395 R ++IR+ G I R+T+E+P F+P +G ++ Sbjct: 508 ---YRIKDIRMMYGVSPWGDSPIDFEDSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQ 564 Query: 396 V--FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVR 453 FRS + + A+A + DS + G++ A + M AL E +R Sbjct: 565 ELNFRSNKNVWGYFSVAAA---GGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIR 621 Query: 454 G-VKTNIAFLQNVLNNQQFLAGTVDTQFID 482 G +T + +L +L + F +DT ++D Sbjct: 622 GDFRTTVEYLIKLLETESFQMNRIDTGWLD 651 >gi|134142062 acetyl-Coenzyme A carboxylase beta [Homo sapiens] Length = 2458 Score = 215 bits (548), Expect = 2e-55 Identities = 156/509 (30%), Positives = 241/509 (47%), Gaps = 74/509 (14%) Query: 37 IKKVMVANRGEIAIRVFRAC---------TELGIRTVAIYSEQDT-GQMHRQKADEAYLI 86 I+KV++AN G A++ R+ E IR V + + +D K + Y+ Sbjct: 260 IEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVP 319 Query: 87 GRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVV 146 G Y ++ I+ +AK V AV G+G SE + GV F+GP E + Sbjct: 320 VPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKNGVAFLGPPSEAM 379 Query: 147 RKMGDKVEARAIAIAAGVPVVPGTDAPIT---------------------------SLHE 179 +GDK+ + +A VP +P + + +T + E Sbjct: 380 WALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGKRISVPEDVYDKGCVKDVDE 439 Query: 180 AHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFI 239 E + GFP++ KA+ GGGG+G+R S E+ + + SE +F+ K Sbjct: 440 GLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSE----IPGSPIFLMKLA 495 Query: 240 EKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLA 299 + RH+EVQIL DQYGN + L+ RDCSIQRRHQK+VE APA + + +++LA Sbjct: 496 QHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEFMEQCAIRLA 555 Query: 300 KQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPD 359 K VGY +AGTVE+L + G +F+E+N RLQVEH TE I DV+L AQ+ +A G L Sbjct: 556 KTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLH- 614 Query: 360 LGLRQENIRI-----------------------NGCAIQCRVTTEDPARSFQPDTGRIEV 396 R ++IR+ G I R+T+E+P F+P +G ++ Sbjct: 615 ---RLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDEGFKPSSGTVQE 671 Query: 397 --FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRG 454 FRS + + A+ + DS + G++ A + M AL E +RG Sbjct: 672 LNFRSSKNVWGYFSVAAT---GGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRG 728 Query: 455 -VKTNIAFLQNVLNNQQFLAGTVDTQFID 482 +T + +L N+L + F +DT ++D Sbjct: 729 DFRTTVEYLINLLETESFQNNDIDTGWLD 757 >gi|18105007 carbamoylphosphate synthetase 2/aspartate transcarbamylase/dihydroorotase [Homo sapiens] Length = 2225 Score = 78.6 bits (192), Expect = 3e-14 Identities = 91/409 (22%), Positives = 173/409 (42%), Gaps = 47/409 (11%) Query: 36 PIKKVMVANRGEIAI-----------RVFRACTELGIRTVAIYSEQDTGQMHRQKADEAY 84 P +KV++ G ++I + +A E I+T+ I T Q + AD+ Y Sbjct: 392 PPRKVLILGSGGLSIGQAGEFDYSGSQAIKALKEENIQTLLINPNIATVQTSQGLADKVY 451 Query: 85 LIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDA--GVRFIGPS 142 + P+ + ++ +I+ + + V G L+ + +A A GVR +G Sbjct: 452 FL-----PITPH-YVTQVIRNERPDGVLLTFGGQTALNCGVELTKAGVLARYGVRVLGTP 505 Query: 143 PEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTYGFPIIFKAAYGGGGR 202 E + D+ A G V P A SL +A + G+P++ +AA+ GG Sbjct: 506 VETIELTEDRRAFAARMAEIGEHVAPSEAA--NSLEQAQAAAERLGYPVLVRAAFALGGL 563 Query: 203 GMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYE 262 G + EEL A++ + V+K ++ + IE +++ D YGN + + Sbjct: 564 GSGFASNREELSALVAPAFAH------TSQVLVDKSLKGWKEIEYEVVRDAYGNCVTV-- 615 Query: 263 RDCSIQR------RHQKVVEIAPAAHLDPQLRTRLTSDSVKLAKQVGYENAGTVEFLVDR 316 C+++ + + +AP+ L+ + L ++K+ + +G V++ ++ Sbjct: 616 --CNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQHLGIVGECNVQYALNP 673 Query: 317 HGKHYF-IEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL------GLRQENIRI 369 + Y+ IEVN+RL + + T L + +A G LP+L G + Sbjct: 674 ESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRNSVTGGTAAFEPSV 733 Query: 370 NGCAIQCRVTTEDPARSFQPDTGRIEVFRS-GEGMGIRLDNASAFQGAV 417 + C + ++ D ++ + T +S GE MGI AFQ A+ Sbjct: 734 DYCVV--KIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKAL 780 Score = 49.3 bits (116), Expect = 2e-05 Identities = 68/304 (22%), Positives = 117/304 (38%), Gaps = 30/304 (9%) Query: 126 DFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSN 185 + A A R +G SPE + ++ + + G+ + ++ L A +F Sbjct: 1022 NMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRE--LSDLESARQFCQ 1079 Query: 186 TYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKPRHI 245 T G+P + + +Y G M V ++ +LE R S A A + + KFI++ + I Sbjct: 1080 TVGYPCVVRPSYVLSGAAMNVAYTDGDLE----RFLSSAAAVSKEHPVVISKFIQEAKEI 1135 Query: 246 EVQ-ILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVK-LAKQVG 303 +V + D + + E + + P PQ T T + +K + VG Sbjct: 1136 DVDAVASDGVVAAIAISEHVENAGVHSGDATLVTP-----PQDITAKTLERIKAIVHAVG 1190 Query: 304 YENAGTVEF---LVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360 E T F L+ + + IE N R+ + VDLV V G + + Sbjct: 1191 QELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVEPV 1250 Query: 361 GLRQENIRINGCAIQCRVTTEDPARSFQPDTGR-----IEVFRSGEGMGIRLDNASAFQG 415 GL + G + V + P SF G +E+ +GE G A+ Sbjct: 1251 GL------MTGSGV---VGVKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLK 1301 Query: 416 AVIS 419 A++S Sbjct: 1302 AMLS 1305 >gi|169790915 carbamoyl-phosphate synthetase 1 isoform a precursor [Homo sapiens] Length = 1506 Score = 59.3 bits (142), Expect = 2e-08 Identities = 74/362 (20%), Positives = 149/362 (41%), Gaps = 38/362 (10%) Query: 19 TSTAPAASPNVRRLEYKPIKKVMVANRGEIAI-----------RVFRACTELGIRTVAI- 66 TS P + R+E + KV++ G ++I + +A E ++TV + Sbjct: 413 TSVLPKPALVASRVE---VSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMN 469 Query: 67 --YSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSER 124 + T ++ ++AD Y + P+ + ++IK + + + G L+ Sbjct: 470 PNIASVQTNEVGLKQADTVYFL-----PITPQF-VTEVIKAEQPDGLILGMGGQTALNCG 523 Query: 125 ADFAQ--ACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHE 182 + + ++ GV+ +G S E + D+ + P + S+ +A + Sbjct: 524 VELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSF--AVESIEDALK 581 Query: 183 FSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKP 242 ++T G+P++ ++AY GG G + + E L + T+A++ + VEK + Sbjct: 582 AADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAM------TNQILVEKSVTGW 635 Query: 243 RHIEVQILGDQYGN---ILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLA 299 + IE +++ D N + ++ D VV +APA L L S+ + Sbjct: 636 KEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVV-VAPAQTLSNAEFQMLRRTSINVV 694 Query: 300 KQVGYENAGTVEFLVDRHGKHY-FIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLP 358 + +G ++F + Y IEVN+RL + + T L +A G LP Sbjct: 695 RHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLP 754 Query: 359 DL 360 ++ Sbjct: 755 EI 756 >gi|21361331 carbamoyl-phosphate synthetase 1 isoform b precursor [Homo sapiens] Length = 1500 Score = 59.3 bits (142), Expect = 2e-08 Identities = 74/362 (20%), Positives = 149/362 (41%), Gaps = 38/362 (10%) Query: 19 TSTAPAASPNVRRLEYKPIKKVMVANRGEIAI-----------RVFRACTELGIRTVAI- 66 TS P + R+E + KV++ G ++I + +A E ++TV + Sbjct: 407 TSVLPKPALVASRVE---VSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMN 463 Query: 67 --YSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSER 124 + T ++ ++AD Y + P+ + ++IK + + + G L+ Sbjct: 464 PNIASVQTNEVGLKQADTVYFL-----PITPQF-VTEVIKAEQPDGLILGMGGQTALNCG 517 Query: 125 ADFAQ--ACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHE 182 + + ++ GV+ +G S E + D+ + P + S+ +A + Sbjct: 518 VELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSF--AVESIEDALK 575 Query: 183 FSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKP 242 ++T G+P++ ++AY GG G + + E L + T+A++ + VEK + Sbjct: 576 AADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAM------TNQILVEKSVTGW 629 Query: 243 RHIEVQILGDQYGN---ILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLA 299 + IE +++ D N + ++ D VV +APA L L S+ + Sbjct: 630 KEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVV-VAPAQTLSNAEFQMLRRTSINVV 688 Query: 300 KQVGYENAGTVEFLVDRHGKHY-FIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLP 358 + +G ++F + Y IEVN+RL + + T L +A G LP Sbjct: 689 RHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLP 748 Query: 359 DL 360 ++ Sbjct: 749 EI 750 >gi|170295797 carbamoyl-phosphate synthetase 1 isoform c [Homo sapiens] Length = 1049 Score = 56.2 bits (134), Expect = 2e-07 Identities = 52/233 (22%), Positives = 99/233 (42%), Gaps = 13/233 (5%) Query: 132 QDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTYGFPI 191 ++ GV+ +G S E + D+ + P + S+ +A + ++T G+P+ Sbjct: 76 KEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSF--AVESIEDALKAADTIGYPV 133 Query: 192 IFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILG 251 + ++AY GG G + + E L + T+A++ + VEK + + IE +++ Sbjct: 134 MIRSAYALGGLGSGICPNRETLMDLSTKAFAM------TNQILVEKSVTGWKEIEYEVVR 187 Query: 252 DQYGN---ILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAKQVGYENAG 308 D N + ++ D VV +APA L L S+ + + +G Sbjct: 188 DADDNCVTVCNMENVDAMGVHTGDSVV-VAPAQTLSNAEFQMLRRTSINVVRHLGIVGEC 246 Query: 309 TVEFLVDRHGKHY-FIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360 ++F + Y IEVN+RL + + T L +A G LP++ Sbjct: 247 NIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEI 299 >gi|109150422 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like 1 isoform b [Homo sapiens] Length = 340 Score = 47.4 bits (111), Expect = 8e-05 Identities = 43/174 (24%), Positives = 69/174 (39%), Gaps = 27/174 (15%) Query: 696 AGGVVEAAIS--YTGDVADPSRTKYSLQYYMGLAEELVRAGTHILCIKDMAGLLKPTACT 753 A G V A+ Y G + T+ S + Y G + + + D G+ P + Sbjct: 179 ARGYVSCALGCPYEGSITPQKVTEVSKRLY--------GMGCYEISLGDTIGVGTPGSMK 230 Query: 754 MLVSSLRDRFPDLPLHIHTHDTSGAGVAAMLACAQAGADVVDVAADSM------SGMTSQ 807 ++ S+ P L +H HDT G +A +L Q G +VVD A + G + Sbjct: 231 RMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGN 290 Query: 808 PSMGALVACTRGTPLDTEVPMERVFDYSEYWEGARGLYAAFDCTATMKSGNSDV 861 + L+ G L+T V + +V + + F C A K+ NS V Sbjct: 291 VATEDLIYMLNGLGLNTGVNLYKVMEAGD-----------FICKAVNKTTNSKV 333 >gi|109150427 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like 1 isoform a [Homo sapiens] Length = 370 Score = 47.4 bits (111), Expect = 8e-05 Identities = 43/174 (24%), Positives = 69/174 (39%), Gaps = 27/174 (15%) Query: 696 AGGVVEAAIS--YTGDVADPSRTKYSLQYYMGLAEELVRAGTHILCIKDMAGLLKPTACT 753 A G V A+ Y G + T+ S + Y G + + + D G+ P + Sbjct: 209 ARGYVSCALGCPYEGSITPQKVTEVSKRLY--------GMGCYEISLGDTIGVGTPGSMK 260 Query: 754 MLVSSLRDRFPDLPLHIHTHDTSGAGVAAMLACAQAGADVVDVAADSM------SGMTSQ 807 ++ S+ P L +H HDT G +A +L Q G +VVD A + G + Sbjct: 261 RMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGN 320 Query: 808 PSMGALVACTRGTPLDTEVPMERVFDYSEYWEGARGLYAAFDCTATMKSGNSDV 861 + L+ G L+T V + +V + + F C A K+ NS V Sbjct: 321 VATEDLIYMLNGLGLNTGVNLYKVMEAGD-----------FICKAVNKTTNSKV 363 >gi|62198232 3-hydroxy-3-methylglutaryl CoA lyase [Homo sapiens] Length = 325 Score = 39.3 bits (90), Expect = 0.022 Identities = 36/154 (23%), Positives = 64/154 (41%), Gaps = 8/154 (5%) Query: 690 MEAAGSAGGVVEAAISYTGDVADPSRTKYSLQYYMGLAEELVRAGTHILCIKDMAGLLKP 749 ++AA SA V +S + P K S + ++ G + + + D G+ P Sbjct: 154 LKAAQSANISVRGYVSCA--LGCPYEGKISPAKVAEVTKKFYSMGCYEISLGDTIGVGTP 211 Query: 750 TACTMLVSSLRDRFPDLPLHIHTHDTSGAGVAAMLACAQAGADVVDVAADSMSGMT-SQP 808 ++S++ P L +H HDT G +A L Q G VVD + + G +Q Sbjct: 212 GIMKDMLSAVMQEVPLAALAVHCHDTYGQALANTLMALQMGVSVVDSSVAGLGGCPYAQG 271 Query: 809 SMG-----ALVACTRGTPLDTEVPMERVFDYSEY 837 + G LV G + T V ++++ + + Sbjct: 272 ASGNLATEDLVYMLEGLGIHTGVNLQKLLEAGNF 305 >gi|219802034 nuclear factor related to kappaB binding protein isoform 1 [Homo sapiens] Length = 1299 Score = 37.0 bits (84), Expect = 0.11 Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 9/57 (15%) Query: 512 PTTPIPVKASPSPTDPVVPAVPIGPPPAGFRDILLREGPEGFARAVRNHPGLLLMDT 568 P TP+ +PT P +PA+PI PPP + + GP + ++ G+LL+ + Sbjct: 719 PVTPV------TPTTPALPAIPISPPPV---SAVNKSGPSTVSEPAKSSSGVLLVSS 766 >gi|23346420 nuclear factor related to kappaB binding protein isoform 2 [Homo sapiens] Length = 1324 Score = 37.0 bits (84), Expect = 0.11 Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 9/57 (15%) Query: 512 PTTPIPVKASPSPTDPVVPAVPIGPPPAGFRDILLREGPEGFARAVRNHPGLLLMDT 568 P TP+ +PT P +PA+PI PPP + + GP + ++ G+LL+ + Sbjct: 744 PVTPV------TPTTPALPAIPISPPPV---SAVNKSGPSTVSEPAKSSSGVLLVSS 791 >gi|115387123 protocadherin 15 isoform CD1-4 precursor [Homo sapiens] Length = 1955 Score = 32.3 bits (72), Expect = 2.7 Identities = 13/33 (39%), Positives = 19/33 (57%) Query: 507 VMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPA 539 V +GP TP + P+P P P++P PPP+ Sbjct: 1800 VSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPS 1832 >gi|218505798 protocadherin 15 isoform CD1-10 precursor [Homo sapiens] Length = 1932 Score = 32.3 bits (72), Expect = 2.7 Identities = 13/33 (39%), Positives = 19/33 (57%) Query: 507 VMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPA 539 V +GP TP + P+P P P++P PPP+ Sbjct: 1777 VSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPS 1809 >gi|218505785 protocadherin 15 isoform CD1-9 precursor [Homo sapiens] Length = 1935 Score = 32.3 bits (72), Expect = 2.7 Identities = 13/33 (39%), Positives = 19/33 (57%) Query: 507 VMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPA 539 V +GP TP + P+P P P++P PPP+ Sbjct: 1780 VSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPS 1812 >gi|218505783 protocadherin 15 isoform CD1-8 precursor [Homo sapiens] Length = 1915 Score = 32.3 bits (72), Expect = 2.7 Identities = 13/33 (39%), Positives = 19/33 (57%) Query: 507 VMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPA 539 V +GP TP + P+P P P++P PPP+ Sbjct: 1760 VSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPS 1792 >gi|218505781 protocadherin 15 isoform CD1-7 precursor [Homo sapiens] Length = 1952 Score = 32.3 bits (72), Expect = 2.7 Identities = 13/33 (39%), Positives = 19/33 (57%) Query: 507 VMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPA 539 V +GP TP + P+P P P++P PPP+ Sbjct: 1797 VSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPS 1829 >gi|218505779 protocadherin 15 isoform CD1-6 precursor [Homo sapiens] Length = 1886 Score = 32.3 bits (72), Expect = 2.7 Identities = 13/33 (39%), Positives = 19/33 (57%) Query: 507 VMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPA 539 V +GP TP + P+P P P++P PPP+ Sbjct: 1731 VSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPS 1763 >gi|218505777 protocadherin 15 isoform CD1-2 precursor [Homo sapiens] Length = 1957 Score = 32.3 bits (72), Expect = 2.7 Identities = 13/33 (39%), Positives = 19/33 (57%) Query: 507 VMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPA 539 V +GP TP + P+P P P++P PPP+ Sbjct: 1802 VSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPS 1834 >gi|218505775 protocadherin 15 isoform CD1-1 precursor [Homo sapiens] Length = 1962 Score = 32.3 bits (72), Expect = 2.7 Identities = 13/33 (39%), Positives = 19/33 (57%) Query: 507 VMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPA 539 V +GP TP + P+P P P++P PPP+ Sbjct: 1807 VSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPS 1839 >gi|53759113 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 2 [Homo sapiens] Length = 372 Score = 31.6 bits (70), Expect = 4.7 Identities = 16/46 (34%), Positives = 22/46 (47%) Query: 520 ASPSPTDPVVPAVPIGPPPAGFRDILLREGPEGFARAVRNHPGLLL 565 A P PT P +P P PP R ++ P R R +PG+L+ Sbjct: 85 ALPGPTAPTLPPCPDSPPGLVGRLLIEFTSPMPLERVQRENPGVLM 130 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.136 0.399 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 44,171,993 Number of Sequences: 37866 Number of extensions: 2087881 Number of successful extensions: 7155 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 30 Number of HSP's successfully gapped in prelim test: 11 Number of HSP's that attempted gapping in prelim test: 7020 Number of HSP's gapped (non-prelim): 103 length of query: 1178 length of database: 18,247,518 effective HSP length: 113 effective length of query: 1065 effective length of database: 13,968,660 effective search space: 14876622900 effective search space used: 14876622900 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.