Guide to the Human Genome
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Search of human proteins with 106049292

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|106049292 pyruvate carboxylase precursor [Homo sapiens]
         (1178 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|106049528 pyruvate carboxylase precursor [Homo sapiens]           2349   0.0  
gi|106049295 pyruvate carboxylase precursor [Homo sapiens]           2349   0.0  
gi|106049292 pyruvate carboxylase precursor [Homo sapiens]           2349   0.0  
gi|65506442 propionyl-Coenzyme A carboxylase, alpha polypeptide ...   377   e-104
gi|189095269 propionyl-Coenzyme A carboxylase, alpha polypeptide...   377   e-104
gi|116805327 methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) pr...   377   e-104
gi|38679977 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo ...   223   6e-58
gi|38679974 acetyl-Coenzyme A carboxylase alpha isoform 4 [Homo ...   223   6e-58
gi|38679971 acetyl-Coenzyme A carboxylase alpha isoform 3 [Homo ...   223   6e-58
gi|38679967 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo ...   223   6e-58
gi|38679960 acetyl-Coenzyme A carboxylase alpha isoform 1 [Homo ...   223   6e-58
gi|134142062 acetyl-Coenzyme A carboxylase beta [Homo sapiens]        215   2e-55
gi|18105007 carbamoylphosphate synthetase 2/aspartate transcarba...    79   3e-14
gi|169790915 carbamoyl-phosphate synthetase 1 isoform a precurso...    59   2e-08
gi|21361331 carbamoyl-phosphate synthetase 1 isoform b precursor...    59   2e-08
gi|170295797 carbamoyl-phosphate synthetase 1 isoform c [Homo sa...    56   2e-07
gi|109150422 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-l...    47   8e-05
gi|109150427 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-l...    47   8e-05
gi|62198232 3-hydroxy-3-methylglutaryl CoA lyase [Homo sapiens]        39   0.022
gi|219802034 nuclear factor related to kappaB binding protein is...    37   0.11 
gi|23346420 nuclear factor related to kappaB binding protein iso...    37   0.11 
gi|115387123 protocadherin 15 isoform CD1-4 precursor [Homo sapi...    32   2.7  
gi|218505798 protocadherin 15 isoform CD1-10 precursor [Homo sap...    32   2.7  
gi|218505785 protocadherin 15 isoform CD1-9 precursor [Homo sapi...    32   2.7  
gi|218505783 protocadherin 15 isoform CD1-8 precursor [Homo sapi...    32   2.7  
gi|218505781 protocadherin 15 isoform CD1-7 precursor [Homo sapi...    32   2.7  
gi|218505779 protocadherin 15 isoform CD1-6 precursor [Homo sapi...    32   2.7  
gi|218505777 protocadherin 15 isoform CD1-2 precursor [Homo sapi...    32   2.7  
gi|218505775 protocadherin 15 isoform CD1-1 precursor [Homo sapi...    32   2.7  
gi|53759113 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 2...    32   4.7  

>gi|106049528 pyruvate carboxylase precursor [Homo sapiens]
          Length = 1178

 Score = 2349 bits (6087), Expect = 0.0
 Identities = 1178/1178 (100%), Positives = 1178/1178 (100%)

Query: 1    MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG 60
            MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
Sbjct: 1    MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG 60

Query: 61   IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF 120
            IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
Sbjct: 61   IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF 120

Query: 121  LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA 180
            LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
Sbjct: 121  LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA 180

Query: 181  HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE 240
            HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
Sbjct: 181  HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE 240

Query: 241  KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK 300
            KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
Sbjct: 241  KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK 300

Query: 301  QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360
            QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
Sbjct: 301  QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360

Query: 361  GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP 420
            GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
Sbjct: 361  GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP 420

Query: 421  HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF 480
            HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
Sbjct: 421  HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF 480

Query: 481  IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG 540
            IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
Sbjct: 481  IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG 540

Query: 541  FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK 600
            FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
Sbjct: 541  FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK 600

Query: 601  LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF 660
            LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
Sbjct: 601  LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF 660

Query: 661  KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL 720
            KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
Sbjct: 661  KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL 720

Query: 721  QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV 780
            QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
Sbjct: 721  QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV 780

Query: 781  AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG 840
            AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
Sbjct: 781  AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG 840

Query: 841  ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM 900
            ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
Sbjct: 841  ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM 900

Query: 901  LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP 960
            LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
Sbjct: 901  LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP 960

Query: 961  EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF 1020
            EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
Sbjct: 961  EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF 1020

Query: 1021 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL 1080
            KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
Sbjct: 1021 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL 1080

Query: 1081 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL 1140
            NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
Sbjct: 1081 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL 1140

Query: 1141 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE 1178
            SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
Sbjct: 1141 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE 1178


>gi|106049295 pyruvate carboxylase precursor [Homo sapiens]
          Length = 1178

 Score = 2349 bits (6087), Expect = 0.0
 Identities = 1178/1178 (100%), Positives = 1178/1178 (100%)

Query: 1    MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG 60
            MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
Sbjct: 1    MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG 60

Query: 61   IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF 120
            IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
Sbjct: 61   IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF 120

Query: 121  LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA 180
            LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
Sbjct: 121  LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA 180

Query: 181  HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE 240
            HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
Sbjct: 181  HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE 240

Query: 241  KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK 300
            KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
Sbjct: 241  KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK 300

Query: 301  QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360
            QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
Sbjct: 301  QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360

Query: 361  GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP 420
            GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
Sbjct: 361  GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP 420

Query: 421  HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF 480
            HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
Sbjct: 421  HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF 480

Query: 481  IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG 540
            IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
Sbjct: 481  IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG 540

Query: 541  FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK 600
            FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
Sbjct: 541  FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK 600

Query: 601  LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF 660
            LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
Sbjct: 601  LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF 660

Query: 661  KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL 720
            KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
Sbjct: 661  KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL 720

Query: 721  QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV 780
            QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
Sbjct: 721  QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV 780

Query: 781  AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG 840
            AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
Sbjct: 781  AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG 840

Query: 841  ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM 900
            ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
Sbjct: 841  ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM 900

Query: 901  LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP 960
            LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
Sbjct: 901  LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP 960

Query: 961  EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF 1020
            EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
Sbjct: 961  EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF 1020

Query: 1021 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL 1080
            KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
Sbjct: 1021 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL 1080

Query: 1081 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL 1140
            NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
Sbjct: 1081 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL 1140

Query: 1141 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE 1178
            SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
Sbjct: 1141 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE 1178


>gi|106049292 pyruvate carboxylase precursor [Homo sapiens]
          Length = 1178

 Score = 2349 bits (6087), Expect = 0.0
 Identities = 1178/1178 (100%), Positives = 1178/1178 (100%)

Query: 1    MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG 60
            MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG
Sbjct: 1    MLKFRTVHGGLRLLGIRRTSTAPAASPNVRRLEYKPIKKVMVANRGEIAIRVFRACTELG 60

Query: 61   IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF 120
            IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF
Sbjct: 61   IRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGF 120

Query: 121  LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA 180
            LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA
Sbjct: 121  LSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEA 180

Query: 181  HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE 240
            HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE
Sbjct: 181  HEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIE 240

Query: 241  KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK 300
            KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK
Sbjct: 241  KPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAK 300

Query: 301  QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360
            QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL
Sbjct: 301  QVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360

Query: 361  GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP 420
            GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP
Sbjct: 361  GLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEVFRSGEGMGIRLDNASAFQGAVISP 420

Query: 421  HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF 480
            HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF
Sbjct: 421  HYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVKTNIAFLQNVLNNQQFLAGTVDTQF 480

Query: 481  IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG 540
            IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG
Sbjct: 481  IDENPELFQLRPAQNRAQKLLHYLGHVMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPAG 540

Query: 541  FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK 600
            FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK
Sbjct: 541  FRDILLREGPEGFARAVRNHPGLLLMDTTFRDAHQSLLATRVRTHDLKKIAPYVAHNFSK 600

Query: 601  LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF 660
            LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF
Sbjct: 601  LFSMENWGGATFDVAMRFLYECPWRRLQELRELIPNIPFQMLLRGANAVGYTNYPDNVVF 660

Query: 661  KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL 720
            KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL
Sbjct: 661  KFCEVAKENGMDVFRVFDSLNYLPNMLLGMEAAGSAGGVVEAAISYTGDVADPSRTKYSL 720

Query: 721  QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV 780
            QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV
Sbjct: 721  QYYMGLAEELVRAGTHILCIKDMAGLLKPTACTMLVSSLRDRFPDLPLHIHTHDTSGAGV 780

Query: 781  AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG 840
            AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG
Sbjct: 781  AAMLACAQAGADVVDVAADSMSGMTSQPSMGALVACTRGTPLDTEVPMERVFDYSEYWEG 840

Query: 841  ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM 900
            ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM
Sbjct: 841  ARGLYAAFDCTATMKSGNSDVYENEIPGGQYTNLHFQAHSMGLGSKFKEVKKAYVEANQM 900

Query: 901  LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP 960
            LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP
Sbjct: 901  LGDLIKVTPSSKIVGDLAQFMVQNGLSRAEAEAQAEELSFPRSVVEFLQGYIGVPHGGFP 960

Query: 961  EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF 1020
            EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF
Sbjct: 961  EPFRSKVLKDLPRVEGRPGASLPPLDLQALEKELVDRHGEEVTPEDVLSAAMYPDVFAHF 1020

Query: 1021 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL 1080
            KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL
Sbjct: 1021 KDFTATFGPLDSLNTRLFLQGPKIAEEFEVELERGKTLHIKALAVSDLNRAGQRQVFFEL 1080

Query: 1081 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL 1140
            NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL
Sbjct: 1081 NGQLRSILVKDTQAMKEMHFHPKALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVL 1140

Query: 1141 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE 1178
            SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE
Sbjct: 1141 SAMKMETVVTSPMEGTVRKVHVTKDMTLEGDDLILEIE 1178


>gi|65506442 propionyl-Coenzyme A carboxylase, alpha polypeptide
           isoform a precursor [Homo sapiens]
          Length = 728

 Score =  377 bits (969), Expect = e-104
 Identities = 202/452 (44%), Positives = 291/452 (64%), Gaps = 9/452 (1%)

Query: 35  KPIKKVMVANRGEIAIRVFRACTELGIRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPV- 93
           K   K++VANRGEIA RV R C ++GI+TVAI+S+ D   +H + ADEA  +G   AP  
Sbjct: 61  KTFDKILVANRGEIACRVIRTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGP--APTS 118

Query: 94  QAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVVRKMGDKV 153
           ++YL++  I++  K+    AVHPGYGFLSE  +FA+      V FIGP    ++ MGDK+
Sbjct: 119 KSYLNMDAIMEAIKKTRAQAVHPGYGFLSENKEFARCLAAEDVVFIGPDTHAIQAMGDKI 178

Query: 154 EARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEEL 213
           E++ +A  A V  +PG D  +    EA   +   G+P++ KA+ GGGG+GMR+    EE 
Sbjct: 179 ESKLLAKKAEVNTIPGFDGVVKDAEEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEET 238

Query: 214 EENYTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQK 273
            + +  +  EA ++FG+  L +EKFI+ PRHIE+Q+LGD++GN L L ER+CSIQRR+QK
Sbjct: 239 RDGFRLSSQEAASSFGDDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQK 298

Query: 274 VVEIAPAAHLDPQLRTRLTSDSVKLAKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEH 333
           VVE AP+  LD + R  +   +V LA+ V Y +AGTVEFLVD     YF+E+N+RLQVEH
Sbjct: 299 VVEEAPSIFLDAETRRAMGEQAVALARAVKYSSAGTVEFLVDSKKNFYFLEMNTRLQVEH 358

Query: 334 TVTEEITDVDLVHAQIHVAEGRSLPDLGLRQENIRINGCAIQCRVTTEDPARSF-QPDTG 392
            VTE IT +DLV   I VA+G  L     +Q +IRING A++CRV  EDP +SF  P  G
Sbjct: 359 PVTECITGLDLVQEMIRVAKGYPLRH---KQADIRINGWAVECRVYAEDPYKSFGLPSIG 415

Query: 393 RIEVFRSGEGM-GIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFR 451
           R+  ++    + G+R+D+     G+ IS +YD ++ K+I +G D   A  +M+ AL  + 
Sbjct: 416 RLSQYQEPLHLPGVRVDSGIQ-PGSDISIYYDPMISKLITYGSDRTEALKRMADALDNYV 474

Query: 452 VRGVKTNIAFLQNVLNNQQFLAGTVDTQFIDE 483
           +RGV  NIA L+ V+ N +F+ G + T+F+ +
Sbjct: 475 IRGVTHNIALLREVIINSRFVKGDISTKFLSD 506



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 30/76 (39%), Positives = 46/76 (60%)

Query: 1103 KALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVLSAMKMETVVTSPMEGTVRKVHV 1162
            K  +D    + +PMPG V+ + V  G  VA+GQ +CV+ AMKM+  +T+   GTV+ VH 
Sbjct: 653  KVTEDTSSVLRSPMPGVVVAVSVKPGDAVAEGQEICVIEAMKMQNSMTAGKTGTVKSVHC 712

Query: 1163 TKDMTLEGDDLILEIE 1178
                T+   DL++E+E
Sbjct: 713  QAGDTVGEGDLLVELE 728


>gi|189095269 propionyl-Coenzyme A carboxylase, alpha polypeptide
           isoform b [Homo sapiens]
          Length = 702

 Score =  377 bits (969), Expect = e-104
 Identities = 202/452 (44%), Positives = 291/452 (64%), Gaps = 9/452 (1%)

Query: 35  KPIKKVMVANRGEIAIRVFRACTELGIRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPV- 93
           K   K++VANRGEIA RV R C ++GI+TVAI+S+ D   +H + ADEA  +G   AP  
Sbjct: 35  KTFDKILVANRGEIACRVIRTCKKMGIKTVAIHSDVDASSVHVKMADEAVCVGP--APTS 92

Query: 94  QAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVVRKMGDKV 153
           ++YL++  I++  K+    AVHPGYGFLSE  +FA+      V FIGP    ++ MGDK+
Sbjct: 93  KSYLNMDAIMEAIKKTRAQAVHPGYGFLSENKEFARCLAAEDVVFIGPDTHAIQAMGDKI 152

Query: 154 EARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEEL 213
           E++ +A  A V  +PG D  +    EA   +   G+P++ KA+ GGGG+GMR+    EE 
Sbjct: 153 ESKLLAKKAEVNTIPGFDGVVKDAEEAVRIAREIGYPVMIKASAGGGGKGMRIAWDDEET 212

Query: 214 EENYTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQK 273
            + +  +  EA ++FG+  L +EKFI+ PRHIE+Q+LGD++GN L L ER+CSIQRR+QK
Sbjct: 213 RDGFRLSSQEAASSFGDDRLLIEKFIDNPRHIEIQVLGDKHGNALWLNERECSIQRRNQK 272

Query: 274 VVEIAPAAHLDPQLRTRLTSDSVKLAKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEH 333
           VVE AP+  LD + R  +   +V LA+ V Y +AGTVEFLVD     YF+E+N+RLQVEH
Sbjct: 273 VVEEAPSIFLDAETRRAMGEQAVALARAVKYSSAGTVEFLVDSKKNFYFLEMNTRLQVEH 332

Query: 334 TVTEEITDVDLVHAQIHVAEGRSLPDLGLRQENIRINGCAIQCRVTTEDPARSF-QPDTG 392
            VTE IT +DLV   I VA+G  L     +Q +IRING A++CRV  EDP +SF  P  G
Sbjct: 333 PVTECITGLDLVQEMIRVAKGYPLRH---KQADIRINGWAVECRVYAEDPYKSFGLPSIG 389

Query: 393 RIEVFRSGEGM-GIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFR 451
           R+  ++    + G+R+D+     G+ IS +YD ++ K+I +G D   A  +M+ AL  + 
Sbjct: 390 RLSQYQEPLHLPGVRVDSGIQ-PGSDISIYYDPMISKLITYGSDRTEALKRMADALDNYV 448

Query: 452 VRGVKTNIAFLQNVLNNQQFLAGTVDTQFIDE 483
           +RGV  NIA L+ V+ N +F+ G + T+F+ +
Sbjct: 449 IRGVTHNIALLREVIINSRFVKGDISTKFLSD 480



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 30/76 (39%), Positives = 46/76 (60%)

Query: 1103 KALKDVKGQIGAPMPGKVIDIKVVAGAKVAKGQPLCVLSAMKMETVVTSPMEGTVRKVHV 1162
            K  +D    + +PMPG V+ + V  G  VA+GQ +CV+ AMKM+  +T+   GTV+ VH 
Sbjct: 627  KVTEDTSSVLRSPMPGVVVAVSVKPGDAVAEGQEICVIEAMKMQNSMTAGKTGTVKSVHC 686

Query: 1163 TKDMTLEGDDLILEIE 1178
                T+   DL++E+E
Sbjct: 687  QAGDTVGEGDLLVELE 702


>gi|116805327 methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)
           precursor [Homo sapiens]
          Length = 725

 Score =  377 bits (967), Expect = e-104
 Identities = 214/540 (39%), Positives = 308/540 (57%), Gaps = 9/540 (1%)

Query: 37  IKKVMVANRGEIAIRVFRACTELGIRTVAIYSEQDTGQMHRQKADEAYLIGRGLAPVQAY 96
           I KV++ANRGEIA RV R   +LG++TVA+YSE D   MH   ADEAY IG   +  Q+Y
Sbjct: 49  ITKVLIANRGEIACRVMRTAKKLGVQTVAVYSEADRNSMHVDMADEAYSIGPAPSQ-QSY 107

Query: 97  LHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVVRKMGDKVEAR 156
           L +  II+VAK +   A+HPG GFLSE  +FA+ C+  G+ FIGP P  +R MG K  ++
Sbjct: 108 LSMEKIIQVAKTSAAQAIHPGCGFLSENMEFAELCKQEGIIFIGPPPSAIRDMGIKSTSK 167

Query: 157 AIAIAAGVPVVPGTDAPITSLHEAHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEEN 216
           +I  AAGVPVV G      S     E +   G+P++ KA  GGGG+GMR+V S +E +E 
Sbjct: 168 SIMAAAGVPVVEGYHGEDQSDQCLKEHARRIGYPVMIKAVRGGGGKGMRIVRSEQEFQEQ 227

Query: 217 YTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVE 276
              A  EA  +F + A+ +EKF++ PRH+EVQ+ GD +GN ++L+ERDCS+QRRHQK++E
Sbjct: 228 LESARREAKKSFNDDAMLIEKFVDTPRHVEVQVFGDHHGNAVYLFERDCSVQRRHQKIIE 287

Query: 277 IAPAAHLDPQLRTRLTSDSVKLAKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVT 336
            APA  +  ++R +L   +V+ AK V Y  AGTVEF++D      F+E+N+RLQVEH VT
Sbjct: 288 EAPAPGIKSEVRKKLGEAAVRAAKAVNYVGAGTVEFIMDSKHNFCFMEMNTRLQVEHPVT 347

Query: 337 EEITDVDLVHAQIHVAEGRSLPDLGLRQENIRINGCAIQCRVTTEDPARSFQPDTGRIEV 396
           E IT  DLV  Q+ +A G  +P   L QE I + G A + R+  EDP+ +F P  G +  
Sbjct: 348 EMITGTDLVEWQLRIAAGEKIP---LSQEEITLQGHAFEARIYAEDPSNNFMPVAGPLVH 404

Query: 397 FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRGVK 456
             +              QG  +S HYD ++ K++    D   A TK+  +L ++ + G+ 
Sbjct: 405 LSTPRADPSTRIETGVRQGDEVSVHYDPMIAKLVVWAADRQAALTKLRYSLRQYNIVGLH 464

Query: 457 TNIAFLQNVLNNQQFLAGTVDTQFIDE-NPELFQLRPAQNRAQKLLHYLGHVMVNGPTTP 515
           TNI FL N+  + +F AG V T FI + + +L   R A  +       LG ++     T 
Sbjct: 465 TNIDFLLNLSGHPEFEAGNVHTDFIPQHHKQLLLSRKAAAKESLCQAALGLILKEKAMTD 524

Query: 516 IPVKASPSPTDPVVPAVPIGPPPAGFRDILLREGPEGFARAVR-NHPG---LLLMDTTFR 571
                +     P   +       +  R++ L++G    A AV  NH G   + + D TF+
Sbjct: 525 TFTLQAHDQFSPFSSSSGRRLNISYTRNMTLKDGKNNVAIAVTYNHDGSYSMQIEDKTFQ 584



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 29/64 (45%), Positives = 35/64 (54%), Gaps = 5/64 (7%)

Query: 1102 PKALKDVKGQIG-----APMPGKVIDIKVVAGAKVAKGQPLCVLSAMKMETVVTSPMEGT 1156
            PK L  V  Q       APM G +  + V AG KV  G  L V+ AMKME  + SP +GT
Sbjct: 634  PKYLSSVSSQETQGGPLAPMTGTIEKVFVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDGT 693

Query: 1157 VRKV 1160
            V+KV
Sbjct: 694  VKKV 697


>gi|38679977 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo
           sapiens]
          Length = 2346

 Score =  223 bits (569), Expect = 6e-58
 Identities = 153/510 (30%), Positives = 248/510 (48%), Gaps = 73/510 (14%)

Query: 35  KPIKKVMVANRGEIAIRVFRAC---------TELGIRTVAIYSEQDT-GQMHRQKADEAY 84
           K I+KV++AN G  A++  R+           E  IR V + + +D        K  + Y
Sbjct: 116 KVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHY 175

Query: 85  LIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPE 144
           +   G      Y ++  I+ +AK   V AV  G+G  SE     +     G+ F+GP  +
Sbjct: 176 VPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQ 235

Query: 145 VVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTY----------------- 187
            +  +GDK+ +  +A  AG+P +P + + +    + ++FS                    
Sbjct: 236 AMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVD 295

Query: 188 ---------GFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKF 238
                    G+P++ KA+ GGGG+G+R V++ ++    +   + +  A      +FV + 
Sbjct: 296 DGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADD----FPNLFRQVQAEVPGSPIFVMRL 351

Query: 239 IEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKL 298
            ++ RH+EVQIL DQYGN + L+ RDCS+QRRHQK++E APA    P +   +   +VKL
Sbjct: 352 AKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKL 411

Query: 299 AKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLP 358
           AK VGY +AGTVE+L  + G  YF+E+N RLQVEH  TE + DV+L  AQ+ +A G  L 
Sbjct: 412 AKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPL- 470

Query: 359 DLGLRQENIRI-----------------------NGCAIQCRVTTEDPARSFQPDTGRIE 395
               R ++IR+                        G  I  R+T+E+P   F+P +G ++
Sbjct: 471 ---YRIKDIRMMYGVSPWGDSPIDFEDSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQ 527

Query: 396 V--FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVR 453
              FRS + +      A+A     +    DS      + G++   A + M  AL E  +R
Sbjct: 528 ELNFRSNKNVWGYFSVAAA---GGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIR 584

Query: 454 G-VKTNIAFLQNVLNNQQFLAGTVDTQFID 482
           G  +T + +L  +L  + F    +DT ++D
Sbjct: 585 GDFRTTVEYLIKLLETESFQMNRIDTGWLD 614


>gi|38679974 acetyl-Coenzyme A carboxylase alpha isoform 4 [Homo
           sapiens]
          Length = 2268

 Score =  223 bits (569), Expect = 6e-58
 Identities = 153/510 (30%), Positives = 248/510 (48%), Gaps = 73/510 (14%)

Query: 35  KPIKKVMVANRGEIAIRVFRAC---------TELGIRTVAIYSEQDT-GQMHRQKADEAY 84
           K I+KV++AN G  A++  R+           E  IR V + + +D        K  + Y
Sbjct: 38  KVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHY 97

Query: 85  LIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPE 144
           +   G      Y ++  I+ +AK   V AV  G+G  SE     +     G+ F+GP  +
Sbjct: 98  VPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQ 157

Query: 145 VVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTY----------------- 187
            +  +GDK+ +  +A  AG+P +P + + +    + ++FS                    
Sbjct: 158 AMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVD 217

Query: 188 ---------GFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKF 238
                    G+P++ KA+ GGGG+G+R V++ ++    +   + +  A      +FV + 
Sbjct: 218 DGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADD----FPNLFRQVQAEVPGSPIFVMRL 273

Query: 239 IEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKL 298
            ++ RH+EVQIL DQYGN + L+ RDCS+QRRHQK++E APA    P +   +   +VKL
Sbjct: 274 AKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKL 333

Query: 299 AKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLP 358
           AK VGY +AGTVE+L  + G  YF+E+N RLQVEH  TE + DV+L  AQ+ +A G  L 
Sbjct: 334 AKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPL- 392

Query: 359 DLGLRQENIRI-----------------------NGCAIQCRVTTEDPARSFQPDTGRIE 395
               R ++IR+                        G  I  R+T+E+P   F+P +G ++
Sbjct: 393 ---YRIKDIRMMYGVSPWGDSPIDFEDSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQ 449

Query: 396 V--FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVR 453
              FRS + +      A+A     +    DS      + G++   A + M  AL E  +R
Sbjct: 450 ELNFRSNKNVWGYFSVAAA---GGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIR 506

Query: 454 G-VKTNIAFLQNVLNNQQFLAGTVDTQFID 482
           G  +T + +L  +L  + F    +DT ++D
Sbjct: 507 GDFRTTVEYLIKLLETESFQMNRIDTGWLD 536


>gi|38679971 acetyl-Coenzyme A carboxylase alpha isoform 3 [Homo
           sapiens]
          Length = 2288

 Score =  223 bits (569), Expect = 6e-58
 Identities = 153/510 (30%), Positives = 248/510 (48%), Gaps = 73/510 (14%)

Query: 35  KPIKKVMVANRGEIAIRVFRAC---------TELGIRTVAIYSEQDT-GQMHRQKADEAY 84
           K I+KV++AN G  A++  R+           E  IR V + + +D        K  + Y
Sbjct: 58  KVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHY 117

Query: 85  LIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPE 144
           +   G      Y ++  I+ +AK   V AV  G+G  SE     +     G+ F+GP  +
Sbjct: 118 VPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQ 177

Query: 145 VVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTY----------------- 187
            +  +GDK+ +  +A  AG+P +P + + +    + ++FS                    
Sbjct: 178 AMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVD 237

Query: 188 ---------GFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKF 238
                    G+P++ KA+ GGGG+G+R V++ ++    +   + +  A      +FV + 
Sbjct: 238 DGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADD----FPNLFRQVQAEVPGSPIFVMRL 293

Query: 239 IEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKL 298
            ++ RH+EVQIL DQYGN + L+ RDCS+QRRHQK++E APA    P +   +   +VKL
Sbjct: 294 AKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKL 353

Query: 299 AKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLP 358
           AK VGY +AGTVE+L  + G  YF+E+N RLQVEH  TE + DV+L  AQ+ +A G  L 
Sbjct: 354 AKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPL- 412

Query: 359 DLGLRQENIRI-----------------------NGCAIQCRVTTEDPARSFQPDTGRIE 395
               R ++IR+                        G  I  R+T+E+P   F+P +G ++
Sbjct: 413 ---YRIKDIRMMYGVSPWGDSPIDFEDSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQ 469

Query: 396 V--FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVR 453
              FRS + +      A+A     +    DS      + G++   A + M  AL E  +R
Sbjct: 470 ELNFRSNKNVWGYFSVAAA---GGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIR 526

Query: 454 G-VKTNIAFLQNVLNNQQFLAGTVDTQFID 482
           G  +T + +L  +L  + F    +DT ++D
Sbjct: 527 GDFRTTVEYLIKLLETESFQMNRIDTGWLD 556


>gi|38679967 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo
           sapiens]
          Length = 2346

 Score =  223 bits (569), Expect = 6e-58
 Identities = 153/510 (30%), Positives = 248/510 (48%), Gaps = 73/510 (14%)

Query: 35  KPIKKVMVANRGEIAIRVFRAC---------TELGIRTVAIYSEQDT-GQMHRQKADEAY 84
           K I+KV++AN G  A++  R+           E  IR V + + +D        K  + Y
Sbjct: 116 KVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHY 175

Query: 85  LIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPE 144
           +   G      Y ++  I+ +AK   V AV  G+G  SE     +     G+ F+GP  +
Sbjct: 176 VPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQ 235

Query: 145 VVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTY----------------- 187
            +  +GDK+ +  +A  AG+P +P + + +    + ++FS                    
Sbjct: 236 AMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVD 295

Query: 188 ---------GFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKF 238
                    G+P++ KA+ GGGG+G+R V++ ++    +   + +  A      +FV + 
Sbjct: 296 DGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADD----FPNLFRQVQAEVPGSPIFVMRL 351

Query: 239 IEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKL 298
            ++ RH+EVQIL DQYGN + L+ RDCS+QRRHQK++E APA    P +   +   +VKL
Sbjct: 352 AKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKL 411

Query: 299 AKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLP 358
           AK VGY +AGTVE+L  + G  YF+E+N RLQVEH  TE + DV+L  AQ+ +A G  L 
Sbjct: 412 AKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPL- 470

Query: 359 DLGLRQENIRI-----------------------NGCAIQCRVTTEDPARSFQPDTGRIE 395
               R ++IR+                        G  I  R+T+E+P   F+P +G ++
Sbjct: 471 ---YRIKDIRMMYGVSPWGDSPIDFEDSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQ 527

Query: 396 V--FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVR 453
              FRS + +      A+A     +    DS      + G++   A + M  AL E  +R
Sbjct: 528 ELNFRSNKNVWGYFSVAAA---GGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIR 584

Query: 454 G-VKTNIAFLQNVLNNQQFLAGTVDTQFID 482
           G  +T + +L  +L  + F    +DT ++D
Sbjct: 585 GDFRTTVEYLIKLLETESFQMNRIDTGWLD 614


>gi|38679960 acetyl-Coenzyme A carboxylase alpha isoform 1 [Homo
           sapiens]
          Length = 2383

 Score =  223 bits (569), Expect = 6e-58
 Identities = 153/510 (30%), Positives = 248/510 (48%), Gaps = 73/510 (14%)

Query: 35  KPIKKVMVANRGEIAIRVFRAC---------TELGIRTVAIYSEQDT-GQMHRQKADEAY 84
           K I+KV++AN G  A++  R+           E  IR V + + +D        K  + Y
Sbjct: 153 KVIEKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHY 212

Query: 85  LIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPE 144
           +   G      Y ++  I+ +AK   V AV  G+G  SE     +     G+ F+GP  +
Sbjct: 213 VPVPGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQ 272

Query: 145 VVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTY----------------- 187
            +  +GDK+ +  +A  AG+P +P + + +    + ++FS                    
Sbjct: 273 AMWALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVD 332

Query: 188 ---------GFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKF 238
                    G+P++ KA+ GGGG+G+R V++ ++    +   + +  A      +FV + 
Sbjct: 333 DGLQAAEEVGYPVMIKASEGGGGKGIRKVNNADD----FPNLFRQVQAEVPGSPIFVMRL 388

Query: 239 IEKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKL 298
            ++ RH+EVQIL DQYGN + L+ RDCS+QRRHQK++E APA    P +   +   +VKL
Sbjct: 389 AKQSRHLEVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPATIATPAVFEHMEQCAVKL 448

Query: 299 AKQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLP 358
           AK VGY +AGTVE+L  + G  YF+E+N RLQVEH  TE + DV+L  AQ+ +A G  L 
Sbjct: 449 AKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPL- 507

Query: 359 DLGLRQENIRI-----------------------NGCAIQCRVTTEDPARSFQPDTGRIE 395
               R ++IR+                        G  I  R+T+E+P   F+P +G ++
Sbjct: 508 ---YRIKDIRMMYGVSPWGDSPIDFEDSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQ 564

Query: 396 V--FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVR 453
              FRS + +      A+A     +    DS      + G++   A + M  AL E  +R
Sbjct: 565 ELNFRSNKNVWGYFSVAAA---GGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIR 621

Query: 454 G-VKTNIAFLQNVLNNQQFLAGTVDTQFID 482
           G  +T + +L  +L  + F    +DT ++D
Sbjct: 622 GDFRTTVEYLIKLLETESFQMNRIDTGWLD 651


>gi|134142062 acetyl-Coenzyme A carboxylase beta [Homo sapiens]
          Length = 2458

 Score =  215 bits (548), Expect = 2e-55
 Identities = 156/509 (30%), Positives = 241/509 (47%), Gaps = 74/509 (14%)

Query: 37  IKKVMVANRGEIAIRVFRAC---------TELGIRTVAIYSEQDT-GQMHRQKADEAYLI 86
           I+KV++AN G  A++  R+           E  IR V + + +D        K  + Y+ 
Sbjct: 260 IEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVP 319

Query: 87  GRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDAGVRFIGPSPEVV 146
             G      Y ++  I+ +AK   V AV  G+G  SE     +     GV F+GP  E +
Sbjct: 320 VPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKNGVAFLGPPSEAM 379

Query: 147 RKMGDKVEARAIAIAAGVPVVPGTDAPIT---------------------------SLHE 179
             +GDK+ +  +A    VP +P + + +T                            + E
Sbjct: 380 WALGDKIASTVVAQTLQVPTLPWSGSGLTVEWTEDDLQQGKRISVPEDVYDKGCVKDVDE 439

Query: 180 AHEFSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFI 239
             E +   GFP++ KA+ GGGG+G+R   S E+    + +  SE         +F+ K  
Sbjct: 440 GLEAAERIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSE----IPGSPIFLMKLA 495

Query: 240 EKPRHIEVQILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLA 299
           +  RH+EVQIL DQYGN + L+ RDCSIQRRHQK+VE APA      +   +   +++LA
Sbjct: 496 QHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIVEEAPATIAPLAIFEFMEQCAIRLA 555

Query: 300 KQVGYENAGTVEFLVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPD 359
           K VGY +AGTVE+L  + G  +F+E+N RLQVEH  TE I DV+L  AQ+ +A G  L  
Sbjct: 556 KTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLH- 614

Query: 360 LGLRQENIRI-----------------------NGCAIQCRVTTEDPARSFQPDTGRIEV 396
              R ++IR+                        G  I  R+T+E+P   F+P +G ++ 
Sbjct: 615 ---RLKDIRLLYGESPWGVTPISFETPSNPPLARGHVIAARITSENPDEGFKPSSGTVQE 671

Query: 397 --FRSGEGMGIRLDNASAFQGAVISPHYDSLLVKVIAHGKDHPTAATKMSRALAEFRVRG 454
             FRS + +      A+      +    DS      + G++   A + M  AL E  +RG
Sbjct: 672 LNFRSSKNVWGYFSVAAT---GGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRG 728

Query: 455 -VKTNIAFLQNVLNNQQFLAGTVDTQFID 482
             +T + +L N+L  + F    +DT ++D
Sbjct: 729 DFRTTVEYLINLLETESFQNNDIDTGWLD 757


>gi|18105007 carbamoylphosphate synthetase 2/aspartate
           transcarbamylase/dihydroorotase [Homo sapiens]
          Length = 2225

 Score = 78.6 bits (192), Expect = 3e-14
 Identities = 91/409 (22%), Positives = 173/409 (42%), Gaps = 47/409 (11%)

Query: 36  PIKKVMVANRGEIAI-----------RVFRACTELGIRTVAIYSEQDTGQMHRQKADEAY 84
           P +KV++   G ++I           +  +A  E  I+T+ I     T Q  +  AD+ Y
Sbjct: 392 PPRKVLILGSGGLSIGQAGEFDYSGSQAIKALKEENIQTLLINPNIATVQTSQGLADKVY 451

Query: 85  LIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSERADFAQACQDA--GVRFIGPS 142
            +     P+  + ++  +I+  + + V     G   L+   +  +A   A  GVR +G  
Sbjct: 452 FL-----PITPH-YVTQVIRNERPDGVLLTFGGQTALNCGVELTKAGVLARYGVRVLGTP 505

Query: 143 PEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTYGFPIIFKAAYGGGGR 202
            E +    D+    A     G  V P   A   SL +A   +   G+P++ +AA+  GG 
Sbjct: 506 VETIELTEDRRAFAARMAEIGEHVAPSEAA--NSLEQAQAAAERLGYPVLVRAAFALGGL 563

Query: 203 GMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILGDQYGNILHLYE 262
           G     + EEL      A++          + V+K ++  + IE +++ D YGN + +  
Sbjct: 564 GSGFASNREELSALVAPAFAH------TSQVLVDKSLKGWKEIEYEVVRDAYGNCVTV-- 615

Query: 263 RDCSIQR------RHQKVVEIAPAAHLDPQLRTRLTSDSVKLAKQVGYENAGTVEFLVDR 316
             C+++          + + +AP+  L+ +    L   ++K+ + +G      V++ ++ 
Sbjct: 616 --CNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQHLGIVGECNVQYALNP 673

Query: 317 HGKHYF-IEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL------GLRQENIRI 369
             + Y+ IEVN+RL     +  + T   L +    +A G  LP+L      G       +
Sbjct: 674 ESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRNSVTGGTAAFEPSV 733

Query: 370 NGCAIQCRVTTEDPARSFQPDTGRIEVFRS-GEGMGIRLDNASAFQGAV 417
           + C +  ++   D ++  +  T      +S GE MGI      AFQ A+
Sbjct: 734 DYCVV--KIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKAL 780



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 68/304 (22%), Positives = 117/304 (38%), Gaps = 30/304 (9%)

Query: 126  DFAQACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSN 185
            + A A      R +G SPE +    ++ +   +    G+      +  ++ L  A +F  
Sbjct: 1022 NMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRE--LSDLESARQFCQ 1079

Query: 186  TYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKPRHI 245
            T G+P + + +Y   G  M V ++  +LE    R  S A A      + + KFI++ + I
Sbjct: 1080 TVGYPCVVRPSYVLSGAAMNVAYTDGDLE----RFLSSAAAVSKEHPVVISKFIQEAKEI 1135

Query: 246  EVQ-ILGDQYGNILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVK-LAKQVG 303
            +V  +  D     + + E   +          + P     PQ  T  T + +K +   VG
Sbjct: 1136 DVDAVASDGVVAAIAISEHVENAGVHSGDATLVTP-----PQDITAKTLERIKAIVHAVG 1190

Query: 304  YENAGTVEF---LVDRHGKHYFIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360
             E   T  F   L+ +  +   IE N R+        +   VDLV     V  G  +  +
Sbjct: 1191 QELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVEPV 1250

Query: 361  GLRQENIRINGCAIQCRVTTEDPARSFQPDTGR-----IEVFRSGEGMGIRLDNASAFQG 415
            GL      + G  +   V  + P  SF    G      +E+  +GE  G       A+  
Sbjct: 1251 GL------MTGSGV---VGVKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLK 1301

Query: 416  AVIS 419
            A++S
Sbjct: 1302 AMLS 1305


>gi|169790915 carbamoyl-phosphate synthetase 1 isoform a precursor
           [Homo sapiens]
          Length = 1506

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 74/362 (20%), Positives = 149/362 (41%), Gaps = 38/362 (10%)

Query: 19  TSTAPAASPNVRRLEYKPIKKVMVANRGEIAI-----------RVFRACTELGIRTVAI- 66
           TS  P  +    R+E   + KV++   G ++I           +  +A  E  ++TV + 
Sbjct: 413 TSVLPKPALVASRVE---VSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMN 469

Query: 67  --YSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSER 124
              +   T ++  ++AD  Y +     P+     + ++IK  + + +     G   L+  
Sbjct: 470 PNIASVQTNEVGLKQADTVYFL-----PITPQF-VTEVIKAEQPDGLILGMGGQTALNCG 523

Query: 125 ADFAQ--ACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHE 182
            +  +    ++ GV+ +G S E +    D+             + P     + S+ +A +
Sbjct: 524 VELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSF--AVESIEDALK 581

Query: 183 FSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKP 242
            ++T G+P++ ++AY  GG G  +  + E L +  T+A++          + VEK +   
Sbjct: 582 AADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAM------TNQILVEKSVTGW 635

Query: 243 RHIEVQILGDQYGN---ILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLA 299
           + IE +++ D   N   + ++   D         VV +APA  L       L   S+ + 
Sbjct: 636 KEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVV-VAPAQTLSNAEFQMLRRTSINVV 694

Query: 300 KQVGYENAGTVEFLVDRHGKHY-FIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLP 358
           + +G      ++F +      Y  IEVN+RL     +  + T   L      +A G  LP
Sbjct: 695 RHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLP 754

Query: 359 DL 360
           ++
Sbjct: 755 EI 756


>gi|21361331 carbamoyl-phosphate synthetase 1 isoform b precursor
           [Homo sapiens]
          Length = 1500

 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 74/362 (20%), Positives = 149/362 (41%), Gaps = 38/362 (10%)

Query: 19  TSTAPAASPNVRRLEYKPIKKVMVANRGEIAI-----------RVFRACTELGIRTVAI- 66
           TS  P  +    R+E   + KV++   G ++I           +  +A  E  ++TV + 
Sbjct: 407 TSVLPKPALVASRVE---VSKVLILGSGGLSIGQAGEFDYSGSQAVKAMKEENVKTVLMN 463

Query: 67  --YSEQDTGQMHRQKADEAYLIGRGLAPVQAYLHIPDIIKVAKENNVDAVHPGYGFLSER 124
              +   T ++  ++AD  Y +     P+     + ++IK  + + +     G   L+  
Sbjct: 464 PNIASVQTNEVGLKQADTVYFL-----PITPQF-VTEVIKAEQPDGLILGMGGQTALNCG 517

Query: 125 ADFAQ--ACQDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHE 182
            +  +    ++ GV+ +G S E +    D+             + P     + S+ +A +
Sbjct: 518 VELFKRGVLKEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSF--AVESIEDALK 575

Query: 183 FSNTYGFPIIFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKP 242
            ++T G+P++ ++AY  GG G  +  + E L +  T+A++          + VEK +   
Sbjct: 576 AADTIGYPVMIRSAYALGGLGSGICPNRETLMDLSTKAFAM------TNQILVEKSVTGW 629

Query: 243 RHIEVQILGDQYGN---ILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLA 299
           + IE +++ D   N   + ++   D         VV +APA  L       L   S+ + 
Sbjct: 630 KEIEYEVVRDADDNCVTVCNMENVDAMGVHTGDSVV-VAPAQTLSNAEFQMLRRTSINVV 688

Query: 300 KQVGYENAGTVEFLVDRHGKHY-FIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLP 358
           + +G      ++F +      Y  IEVN+RL     +  + T   L      +A G  LP
Sbjct: 689 RHLGIVGECNIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLP 748

Query: 359 DL 360
           ++
Sbjct: 749 EI 750


>gi|170295797 carbamoyl-phosphate synthetase 1 isoform c [Homo
           sapiens]
          Length = 1049

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 52/233 (22%), Positives = 99/233 (42%), Gaps = 13/233 (5%)

Query: 132 QDAGVRFIGPSPEVVRKMGDKVEARAIAIAAGVPVVPGTDAPITSLHEAHEFSNTYGFPI 191
           ++ GV+ +G S E +    D+             + P     + S+ +A + ++T G+P+
Sbjct: 76  KEYGVKVLGTSVESIMATEDRQLFSDKLNEINEKIAPSF--AVESIEDALKAADTIGYPV 133

Query: 192 IFKAAYGGGGRGMRVVHSYEELEENYTRAYSEALAAFGNGALFVEKFIEKPRHIEVQILG 251
           + ++AY  GG G  +  + E L +  T+A++          + VEK +   + IE +++ 
Sbjct: 134 MIRSAYALGGLGSGICPNRETLMDLSTKAFAM------TNQILVEKSVTGWKEIEYEVVR 187

Query: 252 DQYGN---ILHLYERDCSIQRRHQKVVEIAPAAHLDPQLRTRLTSDSVKLAKQVGYENAG 308
           D   N   + ++   D         VV +APA  L       L   S+ + + +G     
Sbjct: 188 DADDNCVTVCNMENVDAMGVHTGDSVV-VAPAQTLSNAEFQMLRRTSINVVRHLGIVGEC 246

Query: 309 TVEFLVDRHGKHY-FIEVNSRLQVEHTVTEEITDVDLVHAQIHVAEGRSLPDL 360
            ++F +      Y  IEVN+RL     +  + T   L      +A G  LP++
Sbjct: 247 NIQFALHPTSMEYCIIEVNARLSRSSALASKATGYPLAFIAAKIALGIPLPEI 299


>gi|109150422 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like
           1 isoform b [Homo sapiens]
          Length = 340

 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 43/174 (24%), Positives = 69/174 (39%), Gaps = 27/174 (15%)

Query: 696 AGGVVEAAIS--YTGDVADPSRTKYSLQYYMGLAEELVRAGTHILCIKDMAGLLKPTACT 753
           A G V  A+   Y G +     T+ S + Y          G + + + D  G+  P +  
Sbjct: 179 ARGYVSCALGCPYEGSITPQKVTEVSKRLY--------GMGCYEISLGDTIGVGTPGSMK 230

Query: 754 MLVSSLRDRFPDLPLHIHTHDTSGAGVAAMLACAQAGADVVDVAADSM------SGMTSQ 807
            ++ S+    P   L +H HDT G  +A +L   Q G +VVD A   +       G +  
Sbjct: 231 RMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGN 290

Query: 808 PSMGALVACTRGTPLDTEVPMERVFDYSEYWEGARGLYAAFDCTATMKSGNSDV 861
            +   L+    G  L+T V + +V +  +           F C A  K+ NS V
Sbjct: 291 VATEDLIYMLNGLGLNTGVNLYKVMEAGD-----------FICKAVNKTTNSKV 333


>gi|109150427 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase-like
           1 isoform a [Homo sapiens]
          Length = 370

 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 43/174 (24%), Positives = 69/174 (39%), Gaps = 27/174 (15%)

Query: 696 AGGVVEAAIS--YTGDVADPSRTKYSLQYYMGLAEELVRAGTHILCIKDMAGLLKPTACT 753
           A G V  A+   Y G +     T+ S + Y          G + + + D  G+  P +  
Sbjct: 209 ARGYVSCALGCPYEGSITPQKVTEVSKRLY--------GMGCYEISLGDTIGVGTPGSMK 260

Query: 754 MLVSSLRDRFPDLPLHIHTHDTSGAGVAAMLACAQAGADVVDVAADSM------SGMTSQ 807
            ++ S+    P   L +H HDT G  +A +L   Q G +VVD A   +       G +  
Sbjct: 261 RMLESVMKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGN 320

Query: 808 PSMGALVACTRGTPLDTEVPMERVFDYSEYWEGARGLYAAFDCTATMKSGNSDV 861
            +   L+    G  L+T V + +V +  +           F C A  K+ NS V
Sbjct: 321 VATEDLIYMLNGLGLNTGVNLYKVMEAGD-----------FICKAVNKTTNSKV 363


>gi|62198232 3-hydroxy-3-methylglutaryl CoA lyase [Homo sapiens]
          Length = 325

 Score = 39.3 bits (90), Expect = 0.022
 Identities = 36/154 (23%), Positives = 64/154 (41%), Gaps = 8/154 (5%)

Query: 690 MEAAGSAGGVVEAAISYTGDVADPSRTKYSLQYYMGLAEELVRAGTHILCIKDMAGLLKP 749
           ++AA SA   V   +S    +  P   K S      + ++    G + + + D  G+  P
Sbjct: 154 LKAAQSANISVRGYVSCA--LGCPYEGKISPAKVAEVTKKFYSMGCYEISLGDTIGVGTP 211

Query: 750 TACTMLVSSLRDRFPDLPLHIHTHDTSGAGVAAMLACAQAGADVVDVAADSMSGMT-SQP 808
                ++S++    P   L +H HDT G  +A  L   Q G  VVD +   + G   +Q 
Sbjct: 212 GIMKDMLSAVMQEVPLAALAVHCHDTYGQALANTLMALQMGVSVVDSSVAGLGGCPYAQG 271

Query: 809 SMG-----ALVACTRGTPLDTEVPMERVFDYSEY 837
           + G      LV    G  + T V ++++ +   +
Sbjct: 272 ASGNLATEDLVYMLEGLGIHTGVNLQKLLEAGNF 305


>gi|219802034 nuclear factor related to kappaB binding protein
           isoform 1 [Homo sapiens]
          Length = 1299

 Score = 37.0 bits (84), Expect = 0.11
 Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 9/57 (15%)

Query: 512 PTTPIPVKASPSPTDPVVPAVPIGPPPAGFRDILLREGPEGFARAVRNHPGLLLMDT 568
           P TP+      +PT P +PA+PI PPP      + + GP   +   ++  G+LL+ +
Sbjct: 719 PVTPV------TPTTPALPAIPISPPPV---SAVNKSGPSTVSEPAKSSSGVLLVSS 766


>gi|23346420 nuclear factor related to kappaB binding protein
           isoform 2 [Homo sapiens]
          Length = 1324

 Score = 37.0 bits (84), Expect = 0.11
 Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 9/57 (15%)

Query: 512 PTTPIPVKASPSPTDPVVPAVPIGPPPAGFRDILLREGPEGFARAVRNHPGLLLMDT 568
           P TP+      +PT P +PA+PI PPP      + + GP   +   ++  G+LL+ +
Sbjct: 744 PVTPV------TPTTPALPAIPISPPPV---SAVNKSGPSTVSEPAKSSSGVLLVSS 791


>gi|115387123 protocadherin 15 isoform CD1-4 precursor [Homo sapiens]
          Length = 1955

 Score = 32.3 bits (72), Expect = 2.7
 Identities = 13/33 (39%), Positives = 19/33 (57%)

Query: 507  VMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPA 539
            V  +GP TP  +   P+P  P  P++P  PPP+
Sbjct: 1800 VSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPS 1832


>gi|218505798 protocadherin 15 isoform CD1-10 precursor [Homo sapiens]
          Length = 1932

 Score = 32.3 bits (72), Expect = 2.7
 Identities = 13/33 (39%), Positives = 19/33 (57%)

Query: 507  VMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPA 539
            V  +GP TP  +   P+P  P  P++P  PPP+
Sbjct: 1777 VSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPS 1809


>gi|218505785 protocadherin 15 isoform CD1-9 precursor [Homo sapiens]
          Length = 1935

 Score = 32.3 bits (72), Expect = 2.7
 Identities = 13/33 (39%), Positives = 19/33 (57%)

Query: 507  VMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPA 539
            V  +GP TP  +   P+P  P  P++P  PPP+
Sbjct: 1780 VSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPS 1812


>gi|218505783 protocadherin 15 isoform CD1-8 precursor [Homo sapiens]
          Length = 1915

 Score = 32.3 bits (72), Expect = 2.7
 Identities = 13/33 (39%), Positives = 19/33 (57%)

Query: 507  VMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPA 539
            V  +GP TP  +   P+P  P  P++P  PPP+
Sbjct: 1760 VSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPS 1792


>gi|218505781 protocadherin 15 isoform CD1-7 precursor [Homo sapiens]
          Length = 1952

 Score = 32.3 bits (72), Expect = 2.7
 Identities = 13/33 (39%), Positives = 19/33 (57%)

Query: 507  VMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPA 539
            V  +GP TP  +   P+P  P  P++P  PPP+
Sbjct: 1797 VSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPS 1829


>gi|218505779 protocadherin 15 isoform CD1-6 precursor [Homo sapiens]
          Length = 1886

 Score = 32.3 bits (72), Expect = 2.7
 Identities = 13/33 (39%), Positives = 19/33 (57%)

Query: 507  VMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPA 539
            V  +GP TP  +   P+P  P  P++P  PPP+
Sbjct: 1731 VSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPS 1763


>gi|218505777 protocadherin 15 isoform CD1-2 precursor [Homo sapiens]
          Length = 1957

 Score = 32.3 bits (72), Expect = 2.7
 Identities = 13/33 (39%), Positives = 19/33 (57%)

Query: 507  VMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPA 539
            V  +GP TP  +   P+P  P  P++P  PPP+
Sbjct: 1802 VSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPS 1834


>gi|218505775 protocadherin 15 isoform CD1-1 precursor [Homo sapiens]
          Length = 1962

 Score = 32.3 bits (72), Expect = 2.7
 Identities = 13/33 (39%), Positives = 19/33 (57%)

Query: 507  VMVNGPTTPIPVKASPSPTDPVVPAVPIGPPPA 539
            V  +GP TP  +   P+P  P  P++P  PPP+
Sbjct: 1807 VSTSGPPTPPLLPPFPTPLPPPPPSIPCPPPPS 1839


>gi|53759113 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 2
           [Homo sapiens]
          Length = 372

 Score = 31.6 bits (70), Expect = 4.7
 Identities = 16/46 (34%), Positives = 22/46 (47%)

Query: 520 ASPSPTDPVVPAVPIGPPPAGFRDILLREGPEGFARAVRNHPGLLL 565
           A P PT P +P  P  PP    R ++    P    R  R +PG+L+
Sbjct: 85  ALPGPTAPTLPPCPDSPPGLVGRLLIEFTSPMPLERVQRENPGVLM 130


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,171,993
Number of Sequences: 37866
Number of extensions: 2087881
Number of successful extensions: 7155
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 7020
Number of HSP's gapped (non-prelim): 103
length of query: 1178
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1065
effective length of database: 13,968,660
effective search space: 14876622900
effective search space used: 14876622900
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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