Guide to the Human Genome
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Search of human proteins with 103485137

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|103485137 defensin, beta 104B precursor [Homo sapiens]
         (72 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|103485139 defensin, beta 104A precursor [Homo sapiens]             154   1e-38
gi|103485137 defensin, beta 104B precursor [Homo sapiens]             154   1e-38
gi|50344744 beta-defensin 108B [Homo sapiens]                          47   3e-06
gi|169166494 PREDICTED: hypothetical protein [Homo sapiens]            47   4e-06
gi|239753808 PREDICTED: hypothetical protein [Homo sapiens]            46   7e-06
gi|239748372 PREDICTED: hypothetical protein [Homo sapiens]            46   7e-06
gi|83582798 beta-defensin 115 [Homo sapiens]                           40   4e-04
gi|16905373 beta-defensin 118 [Homo sapiens]                           36   0.007
gi|82734223 beta-defensin 124 [Homo sapiens]                           35   0.017
gi|58865339 defensin, beta 121 [Homo sapiens]                          34   0.022
gi|82734214 beta-defensin 111 [Homo sapiens]                           34   0.028
gi|22748617 defensin, beta 105A precursor [Homo sapiens]               33   0.037
gi|103485141 defensin, beta 105B precursor [Homo sapiens]              33   0.037
gi|83582800 beta-defensin 116 [Homo sapiens]                           32   0.082
gi|21040279 defensin, beta 127 preproprotein [Homo sapiens]            32   0.14 
gi|239749357 PREDICTED: hypothetical protein XP_002347009 [Homo ...    31   0.24 
gi|149944551 defensin, beta 131 [Homo sapiens]                         30   0.31 
gi|18250304 beta defensin 129 precursor [Homo sapiens]                 30   0.31 
gi|169172906 PREDICTED: similar to defensin, beta 131 [Homo sapi...    30   0.41 
gi|37704382 defensin, beta 119 isoform a precursor [Homo sapiens]      30   0.41 
gi|190358539 mitochondrial glycerol 3-phosphate acyltransferase ...    28   1.2  
gi|169202989 PREDICTED: similar to defensin, beta 131 [Homo sapi...    28   1.2  
gi|169173154 PREDICTED: hypothetical protein [Homo sapiens]            28   1.2  
gi|169203494 PREDICTED: similar to defensin, beta 131 [Homo sapi...    28   1.2  
gi|169172390 PREDICTED: similar to defensin, beta 131 [Homo sapi...    28   1.2  
gi|169202282 PREDICTED: similar to defensin, beta 131 [Homo sapi...    28   1.2  
gi|83582802 beta-defensin 128 [Homo sapiens]                           28   1.2  
gi|4503305 defensin, alpha 6 preproprotein [Homo sapiens]              28   1.5  
gi|82734217 beta-defensin 112 [Homo sapiens]                           28   1.5  
gi|23503331 defensin, beta 123 precursor [Homo sapiens]                28   1.5  

>gi|103485139 defensin, beta 104A precursor [Homo sapiens]
          Length = 72

 Score =  154 bits (389), Expect = 1e-38
 Identities = 72/72 (100%), Positives = 72/72 (100%)

Query: 1  MQRLVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLR 60
          MQRLVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLR
Sbjct: 1  MQRLVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLR 60

Query: 61 KWDESLLNRTKP 72
          KWDESLLNRTKP
Sbjct: 61 KWDESLLNRTKP 72


>gi|103485137 defensin, beta 104B precursor [Homo sapiens]
          Length = 72

 Score =  154 bits (389), Expect = 1e-38
 Identities = 72/72 (100%), Positives = 72/72 (100%)

Query: 1  MQRLVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLR 60
          MQRLVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLR
Sbjct: 1  MQRLVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLR 60

Query: 61 KWDESLLNRTKP 72
          KWDESLLNRTKP
Sbjct: 61 KWDESLLNRTKP 72


>gi|50344744 beta-defensin 108B [Homo sapiens]
          Length = 73

 Score = 47.0 bits (110), Expect = 3e-06
 Identities = 26/72 (36%), Positives = 34/72 (47%), Gaps = 2/72 (2%)

Query: 1  MQRLVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLR 60
          M+  VLL AI   + Q LP R +F+   IC      CR  C   E  +GRC N+  CCL 
Sbjct: 1  MRIAVLLFAIFFFMSQVLPARGKFK--EICERPNGSCRDFCLETEIHVGRCLNSQPCCLP 58

Query: 61 KWDESLLNRTKP 72
             +  +  T P
Sbjct: 59 LGHQPRIESTTP 70


>gi|169166494 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 73

 Score = 46.6 bits (109), Expect = 4e-06
 Identities = 26/72 (36%), Positives = 34/72 (47%), Gaps = 2/72 (2%)

Query: 1  MQRLVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLR 60
          M+  VLL AI   + Q LP R +F+   IC      CR  C   E  +GRC N+  CCL 
Sbjct: 1  MRIAVLLFAIFFFMSQVLPARGKFK--EICERPNGSCRDFCLETEIHVGRCLNSRPCCLP 58

Query: 61 KWDESLLNRTKP 72
             +  +  T P
Sbjct: 59 LGHQPRIESTTP 70


>gi|239753808 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 83

 Score = 45.8 bits (107), Expect = 7e-06
 Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 5  VLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRKWDE 64
          VLL AI   + Q LP R +F+   IC      CR  C   E  +GRC N+  CCL    +
Sbjct: 15 VLLFAIFFFMSQVLPARGKFK--EICERPNGSCRDFCLETEIHVGRCLNSRPCCLPLGHQ 72

Query: 65 SLLNRTKP 72
            +  T P
Sbjct: 73 PRIESTTP 80


>gi|239748372 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 83

 Score = 45.8 bits (107), Expect = 7e-06
 Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 2/68 (2%)

Query: 5  VLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRKWDE 64
          VLL AI   + Q LP R +F+   IC      CR  C   E  +GRC N+  CCL    +
Sbjct: 15 VLLFAIFFFMSQVLPARGKFK--EICERPNGSCRDFCLETEIHVGRCLNSRPCCLPLGHQ 72

Query: 65 SLLNRTKP 72
            +  T P
Sbjct: 73 PRIESTTP 80


>gi|83582798 beta-defensin 115 [Homo sapiens]
          Length = 88

 Score = 40.0 bits (92), Expect = 4e-04
 Identities = 22/62 (35%), Positives = 31/62 (50%), Gaps = 4/62 (6%)

Query: 5  VLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRKWDE 64
          VL L + ++L Q  P        R C YGT RCRK C+  E +  +C   + CC+ K  +
Sbjct: 17 VLALVVLVVLAQTAPDG----WIRRCYYGTGRCRKSCKEIERKKEKCGEKHICCVPKEKD 72

Query: 65 SL 66
           L
Sbjct: 73 KL 74


>gi|16905373 beta-defensin 118 [Homo sapiens]
          Length = 123

 Score = 35.8 bits (81), Expect = 0.007
 Identities = 20/59 (33%), Positives = 31/59 (52%), Gaps = 3/59 (5%)

Query: 1  MQRLVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCL 59
          M+ L+L L + +LL Q +P  S    ++ C   +  CRK+C+  E     C N  ACC+
Sbjct: 1  MKLLLLALPMLVLLPQVIPAYSG---EKKCWNRSGHCRKQCKDGEAVKDTCKNLRACCI 56


>gi|82734223 beta-defensin 124 [Homo sapiens]
          Length = 71

 Score = 34.7 bits (78), Expect = 0.017
 Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 4/56 (7%)

Query: 5  VLLLAISLLLYQDLPV-RSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCL 59
          +LL  ++LL+   +P  RSEF+    C  G   C+  C  QE  +  CP+   CCL
Sbjct: 4  LLLFLVALLVLGHVPSGRSEFKR---CWKGQGACQTYCTRQETYMHLCPDASLCCL 56


>gi|58865339 defensin, beta 121 [Homo sapiens]
          Length = 76

 Score = 34.3 bits (77), Expect = 0.022
 Identities = 20/59 (33%), Positives = 27/59 (45%), Gaps = 7/59 (11%)

Query: 1  MQRLVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCL 59
          M+ L+LLL ++LLL Q  PV         C   + RCR  C+  E     C     CC+
Sbjct: 1  MKLLLLLLTVTLLLAQVTPVMK-------CWGKSGRCRTTCKESEVYYILCKTEAKCCV 52


>gi|82734214 beta-defensin 111 [Homo sapiens]
          Length = 67

 Score = 33.9 bits (76), Expect = 0.028
 Identities = 16/45 (35%), Positives = 23/45 (51%), Gaps = 3/45 (6%)

Query: 19 PVRSEFELDRICGYGTARCRKKCRSQEYRIGRC--PNTYACCLRK 61
          P     +L R C  G  +C+ +C   E RI  C  P T+ CCL++
Sbjct: 24 PEYGSLDLRRECRIGNGQCKNQCHENEIRIAYCIRPGTH-CCLQQ 67


>gi|22748617 defensin, beta 105A precursor [Homo sapiens]
          Length = 78

 Score = 33.5 bits (75), Expect = 0.037
 Identities = 13/39 (33%), Positives = 19/39 (48%)

Query: 23 EFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRK 61
          EF +   C  G  +CRK+C   E   G C   + CC ++
Sbjct: 39 EFAVCESCKLGRGKCRKECLENEKPDGNCRLNFLCCRQR 77


>gi|103485141 defensin, beta 105B precursor [Homo sapiens]
          Length = 78

 Score = 33.5 bits (75), Expect = 0.037
 Identities = 13/39 (33%), Positives = 19/39 (48%)

Query: 23 EFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRK 61
          EF +   C  G  +CRK+C   E   G C   + CC ++
Sbjct: 39 EFAVCESCKLGRGKCRKECLENEKPDGNCRLNFLCCRQR 77


>gi|83582800 beta-defensin 116 [Homo sapiens]
          Length = 102

 Score = 32.3 bits (72), Expect = 0.082
 Identities = 21/67 (31%), Positives = 29/67 (43%), Gaps = 7/67 (10%)

Query: 1  MQRLVLLLAISLLLYQDLP---VRSEFELDRI----CGYGTARCRKKCRSQEYRIGRCPN 53
          M+  ++ +AI ++L Q  P    RS     R     C      CR  CR  E +   CPN
Sbjct: 4  MKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTCPN 63

Query: 54 TYACCLR 60
             CCL+
Sbjct: 64 DQKCCLK 70


>gi|21040279 defensin, beta 127 preproprotein [Homo sapiens]
          Length = 99

 Score = 31.6 bits (70), Expect = 0.14
 Identities = 24/70 (34%), Positives = 31/70 (44%), Gaps = 6/70 (8%)

Query: 6  LLLAISLLLYQDLPVRSEFELDRIC--GYGTARCRKKCRSQEYRIGRCPNTYACCLR-KW 62
          L + I++LL+Q   V  + +    C   Y    CRK CR  E     C N   CCL  K 
Sbjct: 3  LFMIIAILLFQKPTVTEQLKK---CWNNYVQGHCRKICRVNEVPEALCENGRYCCLNIKE 59

Query: 63 DESLLNRTKP 72
           E+    TKP
Sbjct: 60 LEACKKITKP 69


>gi|239749357 PREDICTED: hypothetical protein XP_002347009 [Homo
          sapiens]
          Length = 111

 Score = 30.8 bits (68), Expect = 0.24
 Identities = 12/31 (38%), Positives = 15/31 (48%)

Query: 29 ICGYGTARCRKKCRSQEYRIGRCPNTYACCL 59
          IC      C+  C   E  +GRC N+  CCL
Sbjct: 65 ICERPNGSCQDFCLETEIHVGRCLNSRPCCL 95


>gi|149944551 defensin, beta 131 [Homo sapiens]
          Length = 70

 Score = 30.4 bits (67), Expect = 0.31
 Identities = 18/61 (29%), Positives = 26/61 (42%), Gaps = 1/61 (1%)

Query: 1  MQRLVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLR 60
          M+ L  +  +  L++   P RS    D  C      CR KC + E+ I  C +   CC  
Sbjct: 1  MRVLFFVFGVLSLMFTVPPARSFISNDE-CPSEYYHCRLKCNADEHAIRYCADFSICCKL 59

Query: 61 K 61
          K
Sbjct: 60 K 60


>gi|18250304 beta defensin 129 precursor [Homo sapiens]
          Length = 183

 Score = 30.4 bits (67), Expect = 0.31
 Identities = 20/57 (35%), Positives = 25/57 (43%), Gaps = 3/57 (5%)

Query: 1  MQRLVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYAC 57
          M+ L  + A  +L YQ   V +EF   R C  G  RCR  C   E  I +C     C
Sbjct: 1  MKLLFPIFASLMLQYQ---VNTEFIGLRRCLMGLGRCRDHCNVDEKEIQKCKMKKCC 54


>gi|169172906 PREDICTED: similar to defensin, beta 131 [Homo
          sapiens]
          Length = 70

 Score = 30.0 bits (66), Expect = 0.41
 Identities = 16/50 (32%), Positives = 21/50 (42%)

Query: 12 LLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRK 61
          L L   +P R  F  +  C      CR KC + E+ I  C +   CC  K
Sbjct: 11 LSLMSTVPPRRSFISNDECPSEYYHCRLKCNADEHAITYCADFSICCKLK 60


>gi|37704382 defensin, beta 119 isoform a precursor [Homo sapiens]
          Length = 84

 Score = 30.0 bits (66), Expect = 0.41
 Identities = 17/58 (29%), Positives = 27/58 (46%)

Query: 5  VLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRKW 62
          +L L +++LL  + PV S       C   +  CR  C+  E     C N  +CCL+ +
Sbjct: 3  LLYLFLAILLAIEEPVISGKRHILRCMGNSGICRASCKKNEQPYLYCRNCQSCCLQSY 60


>gi|190358539 mitochondrial glycerol 3-phosphate acyltransferase
          [Homo sapiens]
          Length = 828

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 14/43 (32%), Positives = 19/43 (44%), Gaps = 13/43 (30%)

Query: 43 SQEYRIGRC-------------PNTYACCLRKWDESLLNRTKP 72
          S EY +GRC             P  +     KW ESL++R +P
Sbjct: 19 SSEYSVGRCKHTSEEWGECGFRPTIFRSATLKWKESLMSRKRP 61


>gi|169202989 PREDICTED: similar to defensin, beta 131 [Homo
          sapiens]
          Length = 70

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 15/50 (30%), Positives = 20/50 (40%)

Query: 12 LLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRK 61
          L L   +P    F  +  C      CR KC + E+ I  C +   CC  K
Sbjct: 11 LSLMSTVPPTRSFTSNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK 60


>gi|169173154 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 70

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 1/61 (1%)

Query: 1  MQRLVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLR 60
          M+ L  +  +  L+    P RS    D  C      CR KC + E+ I  C +   CC  
Sbjct: 1  MRVLFFVFGVLSLMSTVPPARSFISNDE-CPSEYYHCRLKCNADEHAIRYCADFSICCKL 59

Query: 61 K 61
          K
Sbjct: 60 K 60


>gi|169203494 PREDICTED: similar to defensin, beta 131 [Homo
          sapiens]
          Length = 70

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 15/50 (30%), Positives = 20/50 (40%)

Query: 12 LLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRK 61
          L L   +P    F  +  C      CR KC + E+ I  C +   CC  K
Sbjct: 11 LSLMSTVPPTRSFTSNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK 60


>gi|169172390 PREDICTED: similar to defensin, beta 131 [Homo
          sapiens]
          Length = 70

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 1/61 (1%)

Query: 1  MQRLVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLR 60
          M+ L  +  +  L+    P RS    D  C      CR KC + E+ I  C +   CC  
Sbjct: 1  MRVLFFVFGVLSLMSTVPPARSFISNDE-CPSEYYHCRLKCNADEHAIRYCADFSICCKL 59

Query: 61 K 61
          K
Sbjct: 60 K 60


>gi|169202282 PREDICTED: similar to defensin, beta 131 [Homo
          sapiens]
          Length = 70

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 15/50 (30%), Positives = 20/50 (40%)

Query: 12 LLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRK 61
          L L   +P    F  +  C      CR KC + E+ I  C +   CC  K
Sbjct: 11 LSLMSTVPPTRSFTSNDECPSEYYHCRLKCNADEHAIRYCADFSICCKLK 60


>gi|83582802 beta-defensin 128 [Homo sapiens]
          Length = 93

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 8/62 (12%)

Query: 6  LLLAISLLLYQDLPVRSEFE--LDRICGYGTARCRKKCR-SQEYRIGRCPNTYACCLRKW 62
          L L + +LL++ L   +  +   +++ GY    CRKKC+  + Y IG C +   CC    
Sbjct: 3  LFLVLIILLFEVLTDGARLKKCFNKVTGY----CRKKCKVGERYEIG-CLSGKLCCANDE 57

Query: 63 DE 64
          +E
Sbjct: 58 EE 59


>gi|4503305 defensin, alpha 6 preproprotein [Homo sapiens]
          Length = 100

 Score = 28.1 bits (61), Expect = 1.5
 Identities = 13/30 (43%), Positives = 14/30 (46%), Gaps = 4/30 (13%)

Query: 34  TARCRKKCRSQEYRIGRCP----NTYACCL 59
           T  CR+ C S EY  G C     N   CCL
Sbjct: 71  TCHCRRSCYSTEYSYGTCTVMGINHRFCCL 100


>gi|82734217 beta-defensin 112 [Homo sapiens]
          Length = 113

 Score = 28.1 bits (61), Expect = 1.5
 Identities = 14/39 (35%), Positives = 21/39 (53%), Gaps = 3/39 (7%)

Query: 36 RCRKKCRSQEYRIGRC--PNTYACCLRKWDESLLNRTKP 72
          RC+ +C   E+RI  C  P T+ CC+ + D +  N   P
Sbjct: 60 RCKNQCDDSEFRISYCARPTTH-CCVTECDPTDPNNWIP 97


>gi|23503331 defensin, beta 123 precursor [Homo sapiens]
          Length = 67

 Score = 28.1 bits (61), Expect = 1.5
 Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 5/60 (8%)

Query: 1  MQRLVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLR 60
          M+ L+L L + LLL Q  P  ++      C     +CR +C  +E     C N   CC++
Sbjct: 1  MKLLLLTLTVLLLLSQLTPGGTQR-----CWNLYGKCRYRCSKKERVYVYCINNKMCCVK 55


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.142    0.464 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,692,131
Number of Sequences: 37866
Number of extensions: 90597
Number of successful extensions: 270
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 235
Number of HSP's gapped (non-prelim): 40
length of query: 72
length of database: 18,247,518
effective HSP length: 45
effective length of query: 27
effective length of database: 16,543,548
effective search space: 446675796
effective search space used: 446675796
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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