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Search of human proteins with 103472005
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|103472005 antigen identified by monoclonal antibody Ki-67
isoform 1 [Homo sapiens]
(3256 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|103472005 antigen identified by monoclonal antibody Ki-67 iso... 6461 0.0
gi|225543215 antigen identified by monoclonal antibody Ki-67 iso... 5481 0.0
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 98 1e-19
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 98 1e-19
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 94 3e-18
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 94 3e-18
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 86 8e-16
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 83 4e-15
gi|91982772 mucin 17 [Homo sapiens] 78 1e-13
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 75 8e-13
gi|150170670 piccolo isoform 2 [Homo sapiens] 75 8e-13
gi|150378539 piccolo isoform 1 [Homo sapiens] 75 8e-13
gi|16554449 zonadhesin isoform 3 [Homo sapiens] 69 6e-11
gi|27881494 zonadhesin isoform 6 [Homo sapiens] 69 6e-11
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 66 6e-10
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 65 8e-10
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 65 1e-09
gi|110349719 titin isoform N2-A [Homo sapiens] 64 2e-09
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 63 5e-09
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 62 9e-09
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 62 1e-08
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 62 1e-08
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 61 2e-08
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 60 4e-08
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 59 6e-08
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 57 2e-07
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 57 2e-07
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 57 4e-07
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 56 5e-07
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 55 1e-06
>gi|103472005 antigen identified by monoclonal antibody Ki-67 isoform
1 [Homo sapiens]
Length = 3256
Score = 6461 bits (16763), Expect = 0.0
Identities = 3256/3256 (100%), Positives = 3256/3256 (100%)
Query: 1 MWPTRRLVTIKRSGVDGPHFPLSLSTCLFGRGIECDIRIQLPVVSKQHCKIEIHEQEAIL 60
MWPTRRLVTIKRSGVDGPHFPLSLSTCLFGRGIECDIRIQLPVVSKQHCKIEIHEQEAIL
Sbjct: 1 MWPTRRLVTIKRSGVDGPHFPLSLSTCLFGRGIECDIRIQLPVVSKQHCKIEIHEQEAIL 60
Query: 61 HNFSSTNPTQVNGSVIDEPVRLKHGDVITIIDRSFRYENESLQNGRKSTEFPRKIREQEP 120
HNFSSTNPTQVNGSVIDEPVRLKHGDVITIIDRSFRYENESLQNGRKSTEFPRKIREQEP
Sbjct: 61 HNFSSTNPTQVNGSVIDEPVRLKHGDVITIIDRSFRYENESLQNGRKSTEFPRKIREQEP 120
Query: 121 ARRVSRSSFSSDPDEKAQDSKAYSKITEGKVSGNPQVHIKNVKEDSTADDSKDSVAQGTT 180
ARRVSRSSFSSDPDEKAQDSKAYSKITEGKVSGNPQVHIKNVKEDSTADDSKDSVAQGTT
Sbjct: 121 ARRVSRSSFSSDPDEKAQDSKAYSKITEGKVSGNPQVHIKNVKEDSTADDSKDSVAQGTT 180
Query: 181 NVHSSEHAGRNGRNAADPISGDFKEISSVKLVSRYGELKSVPTTQCLDNSKKNESPFWKL 240
NVHSSEHAGRNGRNAADPISGDFKEISSVKLVSRYGELKSVPTTQCLDNSKKNESPFWKL
Sbjct: 181 NVHSSEHAGRNGRNAADPISGDFKEISSVKLVSRYGELKSVPTTQCLDNSKKNESPFWKL 240
Query: 241 YESVKKELDVKSQKENVLQYCRKSGLQTDYATEKESADGLQGETQLLVSRKSRPKSGGSG 300
YESVKKELDVKSQKENVLQYCRKSGLQTDYATEKESADGLQGETQLLVSRKSRPKSGGSG
Sbjct: 241 YESVKKELDVKSQKENVLQYCRKSGLQTDYATEKESADGLQGETQLLVSRKSRPKSGGSG 300
Query: 301 HAVAEPASPEQELDQNKGKGRDVESVQTPSKAVGASFPLYEPAKMKTPVQYSQQQNSPQK 360
HAVAEPASPEQELDQNKGKGRDVESVQTPSKAVGASFPLYEPAKMKTPVQYSQQQNSPQK
Sbjct: 301 HAVAEPASPEQELDQNKGKGRDVESVQTPSKAVGASFPLYEPAKMKTPVQYSQQQNSPQK 360
Query: 361 HKNKDLYTTGRRESVNLGKSEGFKAGDKTLTPRKLSTRNRTPAKVEDAADSATKPENLSS 420
HKNKDLYTTGRRESVNLGKSEGFKAGDKTLTPRKLSTRNRTPAKVEDAADSATKPENLSS
Sbjct: 361 HKNKDLYTTGRRESVNLGKSEGFKAGDKTLTPRKLSTRNRTPAKVEDAADSATKPENLSS 420
Query: 421 KTRGSIPTDVEVLPTETEIHNEPFLTLWLTQVERKIQKDSLSKPEKLGTTAGQMCSGLPG 480
KTRGSIPTDVEVLPTETEIHNEPFLTLWLTQVERKIQKDSLSKPEKLGTTAGQMCSGLPG
Sbjct: 421 KTRGSIPTDVEVLPTETEIHNEPFLTLWLTQVERKIQKDSLSKPEKLGTTAGQMCSGLPG 480
Query: 481 LSSVDINNFGDSINESEGIPLKRRRVSFGGHLRPELFDENLPPNTPLKRGEAPTKRKSLV 540
LSSVDINNFGDSINESEGIPLKRRRVSFGGHLRPELFDENLPPNTPLKRGEAPTKRKSLV
Sbjct: 481 LSSVDINNFGDSINESEGIPLKRRRVSFGGHLRPELFDENLPPNTPLKRGEAPTKRKSLV 540
Query: 541 MHTPPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSLVISPPAPSPRKTPVASDQRRRSCK 600
MHTPPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSLVISPPAPSPRKTPVASDQRRRSCK
Sbjct: 541 MHTPPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSLVISPPAPSPRKTPVASDQRRRSCK 600
Query: 601 TAPASSSKSQTEVPKRGGRKSGNLPSKRVSISRSQHDILQMICSKRRSGASEANLIVAKS 660
TAPASSSKSQTEVPKRGGRKSGNLPSKRVSISRSQHDILQMICSKRRSGASEANLIVAKS
Sbjct: 601 TAPASSSKSQTEVPKRGGRKSGNLPSKRVSISRSQHDILQMICSKRRSGASEANLIVAKS 660
Query: 661 WADVVKLGAKQTQTKVIKHGPQRSMNKRQRRPATPKKPVGEVHSQFSTGHANSPCTIIIG 720
WADVVKLGAKQTQTKVIKHGPQRSMNKRQRRPATPKKPVGEVHSQFSTGHANSPCTIIIG
Sbjct: 661 WADVVKLGAKQTQTKVIKHGPQRSMNKRQRRPATPKKPVGEVHSQFSTGHANSPCTIIIG 720
Query: 721 KAHTEKVHVPARPYRVLNNFISNQKMDFKEDLSGIAEMFKTPVKEQPQLTSTCHIAISNS 780
KAHTEKVHVPARPYRVLNNFISNQKMDFKEDLSGIAEMFKTPVKEQPQLTSTCHIAISNS
Sbjct: 721 KAHTEKVHVPARPYRVLNNFISNQKMDFKEDLSGIAEMFKTPVKEQPQLTSTCHIAISNS 780
Query: 781 ENLLGKQFQGTDSGEEPLLPTSESFGGNVFFSAQNAAKQPSDKCSASPPLRRQCIRENGN 840
ENLLGKQFQGTDSGEEPLLPTSESFGGNVFFSAQNAAKQPSDKCSASPPLRRQCIRENGN
Sbjct: 781 ENLLGKQFQGTDSGEEPLLPTSESFGGNVFFSAQNAAKQPSDKCSASPPLRRQCIRENGN 840
Query: 841 VAKTPRNTYKMTSLETKTSDTETEPSKTVSTANRSGRSTEFRNIQKLPVESKSEETNTEI 900
VAKTPRNTYKMTSLETKTSDTETEPSKTVSTANRSGRSTEFRNIQKLPVESKSEETNTEI
Sbjct: 841 VAKTPRNTYKMTSLETKTSDTETEPSKTVSTANRSGRSTEFRNIQKLPVESKSEETNTEI 900
Query: 901 VECILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDEKMKAMKRSRTWGQKCAP 960
VECILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDEKMKAMKRSRTWGQKCAP
Sbjct: 901 VECILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDEKMKAMKRSRTWGQKCAP 960
Query: 961 MSDLTDLKSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPTH 1020
MSDLTDLKSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPTH
Sbjct: 961 MSDLTDLKSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPTH 1020
Query: 1021 TKQQLKASLGKVGVKEELLAVGKFTRTSGETTHTHREPAGDGKSIRTFKESPKQILDPAA 1080
TKQQLKASLGKVGVKEELLAVGKFTRTSGETTHTHREPAGDGKSIRTFKESPKQILDPAA
Sbjct: 1021 TKQQLKASLGKVGVKEELLAVGKFTRTSGETTHTHREPAGDGKSIRTFKESPKQILDPAA 1080
Query: 1081 RVTGMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACKSPPPESVDTP 1140
RVTGMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACKSPPPESVDTP
Sbjct: 1081 RVTGMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACKSPPPESVDTP 1140
Query: 1141 TSTKQWPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDL 1200
TSTKQWPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDL
Sbjct: 1141 TSTKQWPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDL 1200
Query: 1201 AGTLPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVD 1260
AGTLPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVD
Sbjct: 1201 AGTLPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVD 1260
Query: 1261 TPTSTKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKL 1320
TPTSTKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKL
Sbjct: 1261 TPTSTKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKL 1320
Query: 1321 DLTENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPES 1380
DLTENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPES
Sbjct: 1321 DLTENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPES 1380
Query: 1381 ADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQ 1440
ADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQ
Sbjct: 1381 ADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQ 1440
Query: 1441 KLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDP 1500
KLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDP
Sbjct: 1441 KLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDP 1500
Query: 1501 VDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQ 1560
VDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQ
Sbjct: 1501 VDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQ 1560
Query: 1561 KLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQP 1620
KLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQP
Sbjct: 1561 KLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQP 1620
Query: 1621 DPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESP 1680
DPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESP
Sbjct: 1621 DPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESP 1680
Query: 1681 KQILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRAS 1740
KQILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRAS
Sbjct: 1681 KQILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRAS 1740
Query: 1741 QPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLG 1800
QPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLG
Sbjct: 1741 QPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLG 1800
Query: 1801 TPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCK 1860
TPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCK
Sbjct: 1801 TPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCK 1860
Query: 1861 SPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTF 1920
SPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTF
Sbjct: 1861 SPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTF 1920
Query: 1921 VGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVS 1980
VGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVS
Sbjct: 1921 VGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVS 1980
Query: 1981 CKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIK 2040
CKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIK
Sbjct: 1981 CKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIK 2040
Query: 2041 AFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTK 2100
AFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTK
Sbjct: 2041 AFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTK 2100
Query: 2101 IACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVF 2160
IACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVF
Sbjct: 2101 IACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVF 2160
Query: 2161 RETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIA 2220
RETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIA
Sbjct: 2161 RETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIA 2220
Query: 2221 CRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMK 2280
CRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMK
Sbjct: 2221 CRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMK 2280
Query: 2281 AFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKI 2340
AFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKI
Sbjct: 2281 AFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKI 2340
Query: 2341 ACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNI 2400
ACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNI
Sbjct: 2341 ACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNI 2400
Query: 2401 NTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKIT 2460
NTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKIT
Sbjct: 2401 NTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKIT 2460
Query: 2461 EVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSK 2520
EVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSK
Sbjct: 2461 EVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSK 2520
Query: 2521 SIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDK 2580
SIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDK
Sbjct: 2521 SIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDK 2580
Query: 2581 NTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGD 2640
NTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGD
Sbjct: 2581 NTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGD 2640
Query: 2641 EGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGK 2700
EGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGK
Sbjct: 2641 EGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGK 2700
Query: 2701 ATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGED 2760
ATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGED
Sbjct: 2701 ATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGED 2760
Query: 2761 KGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKT 2820
KGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKT
Sbjct: 2761 KGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKT 2820
Query: 2821 TKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGK 2880
TKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGK
Sbjct: 2821 TKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGK 2880
Query: 2881 GTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAAD 2940
GTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAAD
Sbjct: 2881 GTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAAD 2940
Query: 2941 SFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGG 3000
SFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGG
Sbjct: 2941 SFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGG 3000
Query: 3001 GKDGSVTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIE 3060
GKDGSVTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIE
Sbjct: 3001 GKDGSVTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIE 3060
Query: 3061 PAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRN 3120
PAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRN
Sbjct: 3061 PAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRN 3120
Query: 3121 EKKPMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAK 3180
EKKPMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAK
Sbjct: 3121 EKKPMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAK 3180
Query: 3181 VLMQNQKGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVTRSVKRCAENPKKAEDNV 3240
VLMQNQKGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVTRSVKRCAENPKKAEDNV
Sbjct: 3181 VLMQNQKGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVTRSVKRCAENPKKAEDNV 3240
Query: 3241 CVKKIRTRSHRDSEDI 3256
CVKKIRTRSHRDSEDI
Sbjct: 3241 CVKKIRTRSHRDSEDI 3256
>gi|225543215 antigen identified by monoclonal antibody Ki-67 isoform
2 [Homo sapiens]
Length = 2896
Score = 5481 bits (14219), Expect = 0.0
Identities = 2764/2773 (99%), Positives = 2767/2773 (99%)
Query: 484 VDINNFGDSINESEGIPLKRRRVSFGGHLRPELFDENLPPNTPLKRGEAPTKRKSLVMHT 543
V ++F +ESEGIPLKRRRVSFGGHLRPELFDENLPPNTPLKRGEAPTKRKSLVMHT
Sbjct: 124 VSRSSFSSDPDESEGIPLKRRRVSFGGHLRPELFDENLPPNTPLKRGEAPTKRKSLVMHT 183
Query: 544 PPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSLVISPPAPSPRKTPVASDQRRRSCKTAP 603
PPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSLVISPPAPSPRKTPVASDQRRRSCKTAP
Sbjct: 184 PPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSLVISPPAPSPRKTPVASDQRRRSCKTAP 243
Query: 604 ASSSKSQTEVPKRGGRKSGNLPSKRVSISRSQHDILQMICSKRRSGASEANLIVAKSWAD 663
ASSSKSQTEVPKRGGRKSGNLPSKRVSISRSQHDILQMICSKRRSGASEANLIVAKSWAD
Sbjct: 244 ASSSKSQTEVPKRGGRKSGNLPSKRVSISRSQHDILQMICSKRRSGASEANLIVAKSWAD 303
Query: 664 VVKLGAKQTQTKVIKHGPQRSMNKRQRRPATPKKPVGEVHSQFSTGHANSPCTIIIGKAH 723
VVKLGAKQTQTKVIKHGPQRSMNKRQRRPATPKKPVGEVHSQFSTGHANSPCTIIIGKAH
Sbjct: 304 VVKLGAKQTQTKVIKHGPQRSMNKRQRRPATPKKPVGEVHSQFSTGHANSPCTIIIGKAH 363
Query: 724 TEKVHVPARPYRVLNNFISNQKMDFKEDLSGIAEMFKTPVKEQPQLTSTCHIAISNSENL 783
TEKVHVPARPYRVLNNFISNQKMDFKEDLSGIAEMFKTPVKEQPQLTSTCHIAISNSENL
Sbjct: 364 TEKVHVPARPYRVLNNFISNQKMDFKEDLSGIAEMFKTPVKEQPQLTSTCHIAISNSENL 423
Query: 784 LGKQFQGTDSGEEPLLPTSESFGGNVFFSAQNAAKQPSDKCSASPPLRRQCIRENGNVAK 843
LGKQFQGTDSGEEPLLPTSESFGGNVFFSAQNAAKQPSDKCSASPPLRRQCIRENGNVAK
Sbjct: 424 LGKQFQGTDSGEEPLLPTSESFGGNVFFSAQNAAKQPSDKCSASPPLRRQCIRENGNVAK 483
Query: 844 TPRNTYKMTSLETKTSDTETEPSKTVSTANRSGRSTEFRNIQKLPVESKSEETNTEIVEC 903
TPRNTYKMTSLETKTSDTETEPSKTVSTANRSGRSTEFRNIQKLPVESKSEETNTEIVEC
Sbjct: 484 TPRNTYKMTSLETKTSDTETEPSKTVSTANRSGRSTEFRNIQKLPVESKSEETNTEIVEC 543
Query: 904 ILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDEKMKAMKRSRTWGQKCAPMSD 963
ILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDEKMKAMKRSRTWGQKCAPMSD
Sbjct: 544 ILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDEKMKAMKRSRTWGQKCAPMSD 603
Query: 964 LTDLKSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPTHTKQ 1023
LTDLKSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPTHTKQ
Sbjct: 604 LTDLKSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPTHTKQ 663
Query: 1024 QLKASLGKVGVKEELLAVGKFTRTSGETTHTHREPAGDGKSIRTFKESPKQILDPAARVT 1083
QLKASLGKVGVKEELLAVGKFTRTSGETTHTHREPAGDGKSIRTFKESPKQILDPAARVT
Sbjct: 664 QLKASLGKVGVKEELLAVGKFTRTSGETTHTHREPAGDGKSIRTFKESPKQILDPAARVT 723
Query: 1084 GMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACKSPPPESVDTPTST 1143
GMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACKSPPPESVDTPTST
Sbjct: 724 GMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACKSPPPESVDTPTST 783
Query: 1144 KQWPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGT 1203
KQWPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGT
Sbjct: 784 KQWPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGT 843
Query: 1204 LPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPT 1263
LPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPT
Sbjct: 844 LPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPT 903
Query: 1264 STKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLT 1323
STKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLT
Sbjct: 904 STKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLT 963
Query: 1324 ENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADT 1383
ENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADT
Sbjct: 964 ENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADT 1023
Query: 1384 PTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLD 1443
PTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLD
Sbjct: 1024 PTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLD 1083
Query: 1444 PAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDT 1503
PAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDT
Sbjct: 1084 PAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDT 1143
Query: 1504 PTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLD 1563
PTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLD
Sbjct: 1144 PTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLD 1203
Query: 1564 LTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPD 1623
LTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPD
Sbjct: 1204 LTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPD 1263
Query: 1624 KNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQI 1683
KNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQI
Sbjct: 1264 KNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQI 1323
Query: 1684 LDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQPD 1743
LDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQPD
Sbjct: 1324 LDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQPD 1383
Query: 1744 LVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPV 1803
LVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPV
Sbjct: 1384 LVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPV 1443
Query: 1804 QKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQ 1863
QKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQ
Sbjct: 1444 QKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQ 1503
Query: 1864 SDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGT 1923
SDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGT
Sbjct: 1504 SDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGT 1563
Query: 1924 PVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKS 1983
PVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKS
Sbjct: 1564 PVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKS 1623
Query: 1984 PQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFK 2043
PQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFK
Sbjct: 1624 PQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFK 1683
Query: 2044 ESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIAC 2103
ESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIAC
Sbjct: 1684 ESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIAC 1743
Query: 2104 KSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRET 2163
KSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRET
Sbjct: 1744 KSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRET 1803
Query: 2164 AKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRS 2223
AKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRS
Sbjct: 1804 AKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRS 1863
Query: 2224 PQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFM 2283
PQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFM
Sbjct: 1864 PQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFM 1923
Query: 2284 GTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACK 2343
GTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACK
Sbjct: 1924 GTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACK 1983
Query: 2344 SPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTF 2403
SPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTF
Sbjct: 1984 SPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTF 2043
Query: 2404 VETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVS 2463
VETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVS
Sbjct: 2044 VETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVS 2103
Query: 2464 CKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIK 2523
CKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIK
Sbjct: 2104 CKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIK 2163
Query: 2524 AFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTK 2583
AFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTK
Sbjct: 2164 AFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTK 2223
Query: 2584 IPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGI 2643
IPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGI
Sbjct: 2224 IPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGI 2283
Query: 2644 KVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATK 2703
KVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATK
Sbjct: 2284 KVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATK 2343
Query: 2704 IPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGI 2763
IPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGI
Sbjct: 2344 IPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGI 2403
Query: 2764 KALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKI 2823
KALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKI
Sbjct: 2404 KALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKI 2463
Query: 2824 PCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTK 2883
PCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTK
Sbjct: 2464 PCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTK 2523
Query: 2884 AFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFT 2943
AFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFT
Sbjct: 2524 AFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFT 2583
Query: 2944 SAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKD 3003
SAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKD
Sbjct: 2584 SAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKD 2643
Query: 3004 GSVTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEPAE 3063
GSVTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEPAE
Sbjct: 2644 GSVTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEPAE 2703
Query: 3064 ELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKK 3123
ELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKK
Sbjct: 2704 ELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKK 2763
Query: 3124 PMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKVLM 3183
PMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKVLM
Sbjct: 2764 PMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKVLM 2823
Query: 3184 QNQKGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVTRSVKRCAENPKKAEDNVCVK 3243
QNQKGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVTRSVKRCAENPKKAEDNVCVK
Sbjct: 2824 QNQKGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVTRSVKRCAENPKKAEDNVCVK 2883
Query: 3244 KIRTRSHRDSEDI 3256
KIRTRSHRDSEDI
Sbjct: 2884 KIRTRSHRDSEDI 2896
Score = 276 bits (707), Expect = 2e-73
Identities = 135/135 (100%), Positives = 135/135 (100%)
Query: 1 MWPTRRLVTIKRSGVDGPHFPLSLSTCLFGRGIECDIRIQLPVVSKQHCKIEIHEQEAIL 60
MWPTRRLVTIKRSGVDGPHFPLSLSTCLFGRGIECDIRIQLPVVSKQHCKIEIHEQEAIL
Sbjct: 1 MWPTRRLVTIKRSGVDGPHFPLSLSTCLFGRGIECDIRIQLPVVSKQHCKIEIHEQEAIL 60
Query: 61 HNFSSTNPTQVNGSVIDEPVRLKHGDVITIIDRSFRYENESLQNGRKSTEFPRKIREQEP 120
HNFSSTNPTQVNGSVIDEPVRLKHGDVITIIDRSFRYENESLQNGRKSTEFPRKIREQEP
Sbjct: 61 HNFSSTNPTQVNGSVIDEPVRLKHGDVITIIDRSFRYENESLQNGRKSTEFPRKIREQEP 120
Query: 121 ARRVSRSSFSSDPDE 135
ARRVSRSSFSSDPDE
Sbjct: 121 ARRVSRSSFSSDPDE 135
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 98.2 bits (243), Expect = 1e-19
Identities = 234/1070 (21%), Positives = 355/1070 (33%), Gaps = 136/1070 (12%)
Query: 1691 TGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKE---SMTNEKTTKVSYRASQPDLVDT 1747
+G+ + +++ +S P + ++ ++ T+E S E ++ S +S +
Sbjct: 82 SGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKI 141
Query: 1748 PTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLD 1807
+S R L+K L + + K TPKP V +E G+ + D
Sbjct: 142 KSSKNSAANRELQKK------LKVKDNKKNRTKKKPTPKPPVVDEA------GSGLDNGD 189
Query: 1808 QPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPA 1867
P ++ T+ K ++T + + P + K T + K +
Sbjct: 190 FKVTTPDTST---TQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETK 246
Query: 1868 DTPTNTKQRPKRSLKKADVEEEFLAFRK-----LTPSAGK-AMHTPKAAVGEEKDINTFV 1921
+T T KQ +K +E + K L P++ A TPKA + T
Sbjct: 247 ETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALT-- 304
Query: 1922 GTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSC 1981
TP E P TPKE A TP E + T K +
Sbjct: 305 -TPKEPT------------PTTPKEPAST------------TP--KEPTPTTIKSAPTTP 337
Query: 1982 KSPQPDPVKT-PTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIK 2040
K P P K+ PT+ K+ + + P T+ TT T +
Sbjct: 338 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 397
Query: 2041 AFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTK 2100
K+ A T E P TPKE A + KE T T K
Sbjct: 398 TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT------KEPAPTTPKEPAPTAPKKPAP 451
Query: 2101 IACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVF 2160
K P P + P T + +P + E + TT + P
Sbjct: 452 TTPKEPAPTTPKEPAPTTTKEPSPTTPK---EPAPTTTKSAPTTTKEPAPTTTKSAPTTP 508
Query: 2161 RETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIA 2220
+E + A T + P TPK A KE T PTT +K
Sbjct: 509 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-----KEPAPTTPKEPAPTTTKKPAPTT 563
Query: 2221 CRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMK 2280
+ P P TP P + + L E+ L TP + P P +E
Sbjct: 564 PKEPAPT---TPKETAPTTPKKLTPTTPEK----LAPTTP------EKPAPTTPEELAPT 610
Query: 2281 AFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKI 2340
+ P P TPKE A + TP PTT ++T
Sbjct: 611 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPK----EPAPTTPKEPAPTTPKETAPT 666
Query: 2341 ACKSPQPDPVDTPAST---KQRPKRNLRKADVEEEFLALRKRTPSA--GKAMDTPK-PAV 2394
K P + PA T K PK E K P+ G A TPK PA
Sbjct: 667 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 726
Query: 2395 SDEKNINTFVETPVQKLDLLGNLPGSKRQPQ--TPKEKAEALEDLVGFKELFQTPGHTEE 2452
+ K TP G P + ++P TPK+ A KEL T
Sbjct: 727 TTPKE--PAPTTPK------GTAPTTLKEPAPTTPKKPAP--------KELAPTTTKGPT 770
Query: 2453 SMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTH 2512
S T DK + K P + K + + P VS T T E T H
Sbjct: 771 STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK-EPTTIH 829
Query: 2513 TEPTGDSKSI------KAFKESPKQILDPAASVTGSRRQLRTRKEKARALE-DLVDFKEL 2565
P + + KA + SPK+ P + + T K + E DL E
Sbjct: 830 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 889
Query: 2566 FSA-PGHTEESMTI-DKNTKIPCKSPPPELTDTAT------------STKRCPKTRPRKE 2611
+A P T+E+ T +K T+ + ++T T T +T PK K+
Sbjct: 890 TTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKK 949
Query: 2612 VKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPKE 2671
+ + +T+ A+ + K K A KKP ++ + R R PK
Sbjct: 950 TITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK--APKKPTSTKKPKTMPRVRKPKT 1007
Query: 2672 KAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTK 2721
P + + EL+ TS + L + T P ++P ++V+ ++
Sbjct: 1008 TPTPRKMTSTMPELNPTSRIAEAML---QTTTRPNQTPNSKLVEVNPKSE 1054
Score = 97.4 bits (241), Expect = 2e-19
Identities = 266/1125 (23%), Positives = 376/1125 (33%), Gaps = 170/1125 (15%)
Query: 800 PTSESFGGNVFFSAQNAAKQPSDKCSASPPLRRQCIRENGNVAKTPRNTYKMTS-LETKT 858
P ESF V N PS K + P Q I+ + P N K +E++
Sbjct: 57 PDYESFCAEV----HNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEE 112
Query: 859 SDTETEPSKTVSTANRSGRSTEFRNIQKLPVESKSEETNTEIVECILKRGQKATLLQQRR 918
E S+ +++ S S+ I+K+ SK+ N E+ + + + K +
Sbjct: 113 ITEEHSVSENQESSSSSSSSSSSSTIRKIK-SSKNSAANRELQKKLKVKDNK------KN 165
Query: 919 EGEMKEIERPFETYKENIELKENDEKMKAMKRSRTWGQKCAPMSDLTDLKSL-------P 971
+ K +P + L D K+ S T K + +T K + P
Sbjct: 166 RTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPP 225
Query: 972 DTELMKDTARGQNLLQTQDHAKAPKSEKGKIT--KMPCQSLQPEPINTPTHTKQQLKAS- 1028
+++ K+T+ N T + + + K T K S + T K S
Sbjct: 226 NSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 285
Query: 1029 -LGKVGVKEELLAVGKFTRTSGE-TTHTHREPAG---DGKSIRTFKESPKQILDPAARVT 1083
L K K E G T E T T +EPA + T K +P +PA T
Sbjct: 286 VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 345
Query: 1084 GMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACKSPPPESVDTPTST 1143
K P TPKE A + + P P+ TTK + P + PT+
Sbjct: 346 --KSAPTTPKEPAPTTT---------KEPAPTTPKEPAPTTTK---EPAPTTTKSAPTTP 391
Query: 1144 KQ----WPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLD 1199
K+ PK+ E ++ TP+ TPK K+ P +
Sbjct: 392 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPT------TPKEPAPTTKE-----PAPTTPKE 440
Query: 1200 LAGTLPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPV 1259
A T P K TPKE P T A TTK P SP +
Sbjct: 441 PAPTAP-KKPAPTTPKE-----------------PAPTTPKEPAPTTTKEP--SPTTPKE 480
Query: 1260 DTPTSTKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQK 1319
PT+TK P + A + SA P P+ +E TP +
Sbjct: 481 PAPTTTKSAPTTTKEPAPTTTK---------SAPTTPKEPSPTTTKEP----APTTPKEP 527
Query: 1320 LDLTENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPE 1379
T K P TPKE P T A TTK P ++P E
Sbjct: 528 APTTP----KKPAPTTPKE-----------------PAPTTPKEPAPTTTKKPAPTTPKE 566
Query: 1380 SADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGE----TTHTDKVP-GGEDKSINAF 1434
A T T P TP + E KL T+ E TT + P E+ +
Sbjct: 567 PAPT-TPKETAPTTPKKLTPTTPE-----KLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 620
Query: 1435 RETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIAC 1494
E A AA T + P T ++ P KE T PTT + T
Sbjct: 621 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP----KEPAPTTPKETAPTTPKGTAPTTL 676
Query: 1495 RSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSA--GKAMHTPK-PAVSGEKNI 1551
+ +P P T KP K E K P+ G A TPK PA +
Sbjct: 677 K-EPAPT---TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT----- 727
Query: 1552 YAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTA 1611
TP + T T T KE A KEL T S T+DK A
Sbjct: 728 -----TPKEPAPTTPKGTAP----TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA 778
Query: 1612 KVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGK 1671
K + P K PA + + V T T+ E T H P
Sbjct: 779 PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPT-TTKEPTTIHKSPDESTP 837
Query: 1672 SM------KAFMESPKQI-LDSAASLTGSKRQLRTPKGKSEVPEDLAGFIE-LFQTPSHT 1723
+ KA SPK+ + + + +K ++ T DL E P T
Sbjct: 838 ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 897
Query: 1724 KE-SMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAM 1782
KE + T EKTT+ A+ + T T K + K T + K+T + + M
Sbjct: 898 KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIM 957
Query: 1783 HTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTP 1842
+ P+ + KD T K +P P + T+K K + R+ TP
Sbjct: 958 NKPE-ETAKPKDRATNSKATTPKPQKPTKAP--KKPTSTKKPKT-----MPRVRKPKTTP 1009
Query: 1843 CTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVE 1887
T K T + +P S A+ T RP ++ VE
Sbjct: 1010 ------TPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVE 1048
Score = 80.5 bits (197), Expect = 3e-14
Identities = 219/1040 (21%), Positives = 330/1040 (31%), Gaps = 154/1040 (14%)
Query: 1980 SCKSPQPDPVK------TPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETA 2033
S K+P P T S K K KV EE+ +++ ++ + ++
Sbjct: 75 SKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSS 134
Query: 2034 GDG-KSIKAFKESAK--------QMLDPANYGTGMERWPRTPK-EEAQSLEDLAGFKELF 2083
+ IK+ K SA ++ D T + P+ P +EA S D FK
Sbjct: 135 SSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFK--V 192
Query: 2084 QTPD-----HTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALK 2138
TPD H + ST+ TT A P S+ + T + + K VE
Sbjct: 193 TTPDTSTTQHNKVSTSPKITT--AKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTT 250
Query: 2139 QLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTG--SKRQPRTPKGKAQPLEDLAG 2196
QT+ K K +T+ + L P + V + + T KG A L
Sbjct: 251 TNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPA-----LTT 305
Query: 2197 LKELFQTPICTDKPTTHEKTTKIACRSPQPDPVG----TPTIFKPQSKRSLRKADVEEES 2252
KE PTT ++ + P P + TP P + +S E
Sbjct: 306 PKE--------PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAP 357
Query: 2253 LALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQA 2312
++ P+ K P P E P + P K P TPKE A
Sbjct: 358 TTTKEPAPTTPKE---PAPTTTKEPAPTTTKSAPTTPKE-PAPTTPKKPAPTTPKEPAPT 413
Query: 2313 LEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEE 2372
TP PTT ++ K P P PA T PK+ E
Sbjct: 414 ------------TPKEPTPTTPKEPAPTT-KEPAPTTPKEPAPTA--PKKPAPTTPKEPA 458
Query: 2373 FLALRKRTPSAGK--AMDTPK-PAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKE 2429
++ P+ K + TPK PA + K+ T + P +K P TPKE
Sbjct: 459 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT--------TKSAPTTPKE 510
Query: 2430 KAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKV 2489
+ KE T T K + K P P + K + + P
Sbjct: 511 PSPTTT-----KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP- 564
Query: 2490 DMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTR 2549
+EP + + + TT PT K E P + T T
Sbjct: 565 ---KEPAPTTP--KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 619
Query: 2550 KEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTA------TSTKRC 2603
E+ P T K P + P E T T+ K
Sbjct: 620 PEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 679
Query: 2604 PKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSR 2663
T P+K +EL+ T KEP S KP P P
Sbjct: 680 APTTPKKPAPKELAPT------------TTKEPTS----------TTCDKPAPTT--PKG 715
Query: 2664 RRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRH 2723
P PKE A T T+ T + A P + P E+ TT
Sbjct: 716 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE----PAPTTPKKPAPKELAPTT------ 765
Query: 2724 LRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGS 2783
T+ ++P+ +T+ TT + P K E+ T + ++ T +
Sbjct: 766 --TKGPTSTTSDKPAPTTPKETA-PTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTT 822
Query: 2784 RRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSS----- 2838
+ + ++ +L+ P A TTK P + PE+ TA
Sbjct: 823 KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD 882
Query: 2839 -KRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFK-------QPAK 2890
+ P T ++ +E + T S T T + + T FK A
Sbjct: 883 LRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP 942
Query: 2891 RKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTP 2950
+ + I + P+E A+P + + + + P T APK+
Sbjct: 943 KVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKP-----------QKPTKAPKKPT 991
Query: 2951 DSGKPLKISRRVLRAPKVEP 2970
+ KP + R +R PK P
Sbjct: 992 STKKPKTMPR--VRKPKTTP 1009
Score = 66.6 bits (161), Expect = 4e-10
Identities = 229/1059 (21%), Positives = 337/1059 (31%), Gaps = 136/1059 (12%)
Query: 1368 TTKMPCESSPPESADTPT---STRRQPKTP--------LEKRDVQKELSALKKLTQTSGE 1416
T+ + +PP S + T +T+R PK P +E ++ +E S + +S
Sbjct: 70 TSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSS 129
Query: 1417 TTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQP---LEDLAGL--- 1470
++ + + KS A ++L V +K++ +TK+K P + D AG
Sbjct: 130 SSSSSSSTIRKIKSSK--NSAANRELQKKLKVKDNKKN-RTKKKPTPKPPVVDEAGSGLD 186
Query: 1471 KELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLR-KVDVEEEFFALRK 1529
F+ T H K + + P++ S P S S + V +E K
Sbjct: 187 NGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETK 246
Query: 1530 RTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALED-- 1587
T + K T EK A ++K ++L + + L P KA+
Sbjct: 247 ETTTTNKQTSTD----GKEKTTSAKETQSIEKTS-AKDLAPTSKVLAKPTPKAETTTKGP 301
Query: 1588 -LAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEEL 1646
L KE T S T + KS+ P K PA + + + K
Sbjct: 302 ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTP-KEPAPTTTKSAPTTPK------- 353
Query: 1647 LAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGKSEV 1706
TT PT + + P +A T + TPK +
Sbjct: 354 --------EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 405
Query: 1707 -PEDLAGFIELFQTPSHTKESMTNEK----TTKVSYRASQPDLVDTPTSSKPQPKRSLRK 1761
P++ A TP+ KE K TT + P T +P P
Sbjct: 406 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 465
Query: 1762 ADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQT 1821
A T ++ +P+ K +PA K T P + T
Sbjct: 466 APTTT-----KEPSPTTPK-----EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 515
Query: 1822 RKEKAQALEELTGFRELFQTPCTDNPTTDEK---TTKKILCKSPQSDPADTPTNTKQ--- 1875
KE A TP PTT +K TT K + +PA PT TK+
Sbjct: 516 TKEPAPT------------TPKEPAPTTPKKPAPTTPKEPAPTTPKEPA--PTTTKKPAP 561
Query: 1876 -RPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLGNL 1934
PK E +KLTP+ + + A EK T TP E L
Sbjct: 562 TTPKEPAPTTPKETAPTTPKKLTPTTPEKL----APTTPEKPAPT---TPEE----LAPT 610
Query: 1935 PGSKRRPQTPKEKAKALEDLAGF---KELFQTPGHTEESMTDDKITEVSCKSPQPDPVK- 1990
+ P TP+E A A KE T T + + K P K
Sbjct: 611 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 670
Query: 1991 -TPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQM 2049
PT+ K+ + K KE K + + T T G + KE A
Sbjct: 671 TAPTTLKEPAPTTPKKPAPKELAPTTTK--EPTSTTCDKPAPTTPKGTAPTTPKEPAPTT 728
Query: 2050 LDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPE 2109
T P T KE A + KEL T STT DK K P
Sbjct: 729 PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 788
Query: 2110 SMDTPTST---RRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQ 2166
+ P T + P TP E+S + T K P + ++ E +
Sbjct: 789 TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA--EPTPK 846
Query: 2167 KLDPAASVTG---SKRQPRTPKGKAQPLEDLAGLKELFQTPICT--------DKPTTHEK 2215
L+ + G +K T +D ++L TP T + TT EK
Sbjct: 847 ALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 906
Query: 2216 TTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGD 2275
TT+ + T T K + K + K+T + + M+ P+
Sbjct: 907 TTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEET-AK 965
Query: 2276 EKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDE 2335
KD K P P K+ T K K P KP T
Sbjct: 966 PKDRATNSKATTPKPQKPTKAP--KKPTSTKKPKTM--------------PRVRKPKTTP 1009
Query: 2336 KTTKIACKSPQPDPVDTPA----STKQRPKRNLRKADVE 2370
K+ P+ +P A T RP + VE
Sbjct: 1010 TPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVE 1048
Score = 50.8 bits (120), Expect = 2e-05
Identities = 99/498 (19%), Positives = 164/498 (32%), Gaps = 53/498 (10%)
Query: 2418 PGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRS 2477
P SK+ P P ++ ++ T++ + ++ITE S ES +S S
Sbjct: 73 PSSKKAPP-PSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSS 131
Query: 2478 SKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAA 2537
S I +K S + Q + + K+ K +PK P
Sbjct: 132 SSSSSTIRKIK----------SSKNSAANRELQKKLKVKDNKKNRTKKKPTPKP---PVV 178
Query: 2538 SVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESM--TIDKNTKIPCKSPPPELTD 2595
GS D DFK T+ + T K T +P P L
Sbjct: 179 DEAGSGL-------------DNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPP 225
Query: 2596 TATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTH-KEPASGDEGIKVLKQRAKKKP 2654
+ ++K T V +E + + T T+ + T T KE + + + +++ + K
Sbjct: 226 NSDTSKETSLT-----VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 280
Query: 2655 NPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVV 2714
P + ++ P+A P T E + T + A+ P E P +
Sbjct: 281 APTSKVLAKPTPKAETTTKGP-----ALTTPKEPTPTTPKE----PASTTPKEPTPTTIK 331
Query: 2715 DTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTP 2774
+ K T + + A T+ TT + P + +SA TP
Sbjct: 332 SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 391
Query: 2775 APAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDT 2834
A T + P P+E A K+P +E TTK P ++P+ E
Sbjct: 392 KEPAPTTPKKPAPTTPKEPAPTTP-----KEPTPTTPKEPA---PTTKEPAPTTPK-EPA 442
Query: 2835 ATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLD 2894
T+ K+ T ++ T+ TT + P K+PA
Sbjct: 443 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 502
Query: 2895 AEDVIGSRRQPRAPKEKA 2912
+ P KE A
Sbjct: 503 SAPTTPKEPSPTTTKEPA 520
Score = 38.9 bits (89), Expect = 0.084
Identities = 102/461 (22%), Positives = 150/461 (32%), Gaps = 88/461 (19%)
Query: 994 APKSEKGKITKMPCQSLQPEPI-NTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETT 1052
APK TK P + +P TP T KE K G
Sbjct: 688 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK-----GTAP 742
Query: 1053 HTHREPAGDGKSIRTFKESPKQILDPAAR----VTGMKKWPRTPKEEAQSLEDLAGFKEL 1108
T +EPA K +PK++ + T K P TPKE A +
Sbjct: 743 TTLKEPAPTTPK----KPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP-------- 790
Query: 1109 FQTPGPSEESMTDEKTTKIACKSPPPES--VDTPTSTKQWPKRSLRKADVEEEFLALRKL 1166
+ P P+ T +K ++PPP + V TPT+TK+ ++ K+ E
Sbjct: 791 -KEPAPT----TPKKPAPTTPETPPPTTSEVSTPTTTKE--PTTIHKSPDES-------- 835
Query: 1167 TPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAG 1226
TP A TPK K+ G P K A T E +D
Sbjct: 836 TPELS-AEPTPKALENSPKE----PGVPTTKTPAA-----------TKPEMTTTAKDKTT 879
Query: 1227 FKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACR 1286
++L TP E AA K TK +T T+T++ + I + +
Sbjct: 880 ERDLRTTP---ETTTAAPKMTK-----------ETATTTEKTTESKITATTTQVTSTTTQ 925
Query: 1287 NLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDL 1346
+ P + T T K+ T+ + P+E A+ +
Sbjct: 926 DTTPFKITTLKTT---------------TLAPKVTTTKKTITTTEIMNKPEETAKPKDRA 970
Query: 1347 TGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSA 1406
T K P +A +TK P T + R+ T E + A
Sbjct: 971 TNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEA 1030
Query: 1407 LKKLTQTSGETTHTDKV---PGGEDKSINAFRETAKQKLDP 1444
+ + T +T ++ V P ED A ET L P
Sbjct: 1031 MLQTTTRPNQTPNSKLVEVNPKSEDAG-GAEGETPHMLLRP 1070
Score = 35.0 bits (79), Expect = 1.2
Identities = 57/264 (21%), Positives = 97/264 (36%), Gaps = 27/264 (10%)
Query: 2996 FKRGGGKDGSVTGTKRLRCMPAPEEIVEEL------PASKKQRVAPRARGKSSEPVVIMK 3049
F+RG D K +C P E E+ P+SKK AP G S K
Sbjct: 37 FERGRECDCDAQCKKYDKCCPDYESFCAEVHNPTSPPSSKK---APPPSGASQTIKSTTK 93
Query: 3050 RSLRTSAKR-----IEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQ 3104
RS + K+ IE E + + N+E S + ++R + +K A +
Sbjct: 94 RSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSS--SSSSSTIRKIKSSKNSAANR 151
Query: 3105 ITEVFVLAERIEINRNEKKPMKTSPEMDIQNP--DDGARK-PIPRDKVTENKRCLRSARQ 3161
+ + + + NR +KKP P +D D+G K P T++ + S +
Sbjct: 152 ELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKI 211
Query: 3162 NESS----QPKVAEESGGQKSAKVLMQN----QKGKGEAGNSDSMCLRSRKTKSQPAAST 3213
+ +P + S K + + + + N + KT S +
Sbjct: 212 TTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQS 271
Query: 3214 LESKSVQRVTRSVKRCAENPKKAE 3237
+E S + + + K A+ KAE
Sbjct: 272 IEKTSAKDLAPTSKVLAKPTPKAE 295
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 98.2 bits (243), Expect = 1e-19
Identities = 234/1070 (21%), Positives = 355/1070 (33%), Gaps = 136/1070 (12%)
Query: 1691 TGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKE---SMTNEKTTKVSYRASQPDLVDT 1747
+G+ + +++ +S P + ++ ++ T+E S E ++ S +S +
Sbjct: 123 SGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKI 182
Query: 1748 PTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLD 1807
+S R L+K L + + K TPKP V +E G+ + D
Sbjct: 183 KSSKNSAANRELQKK------LKVKDNKKNRTKKKPTPKPPVVDEA------GSGLDNGD 230
Query: 1808 QPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPA 1867
P ++ T+ K ++T + + P + K T + K +
Sbjct: 231 FKVTTPDTST---TQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETK 287
Query: 1868 DTPTNTKQRPKRSLKKADVEEEFLAFRK-----LTPSAGK-AMHTPKAAVGEEKDINTFV 1921
+T T KQ +K +E + K L P++ A TPKA + T
Sbjct: 288 ETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALT-- 345
Query: 1922 GTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSC 1981
TP E P TPKE A TP E + T K +
Sbjct: 346 -TPKEPT------------PTTPKEPAST------------TP--KEPTPTTIKSAPTTP 378
Query: 1982 KSPQPDPVKT-PTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIK 2040
K P P K+ PT+ K+ + + P T+ TT T +
Sbjct: 379 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPT 438
Query: 2041 AFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTK 2100
K+ A T E P TPKE A + KE T T K
Sbjct: 439 TPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT------KEPAPTTPKEPAPTAPKKPAP 492
Query: 2101 IACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVF 2160
K P P + P T + +P + E + TT + P
Sbjct: 493 TTPKEPAPTTPKEPAPTTTKEPSPTTPK---EPAPTTTKSAPTTTKEPAPTTTKSAPTTP 549
Query: 2161 RETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIA 2220
+E + A T + P TPK A KE T PTT +K
Sbjct: 550 KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP-----KEPAPTTPKEPAPTTTKKPAPTT 604
Query: 2221 CRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMK 2280
+ P P TP P + + L E+ L TP + P P +E
Sbjct: 605 PKEPAPT---TPKETAPTTPKKLTPTTPEK----LAPTTP------EKPAPTTPEELAPT 651
Query: 2281 AFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKI 2340
+ P P TPKE A + TP PTT ++T
Sbjct: 652 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPK----EPAPTTPKEPAPTTPKETAPT 707
Query: 2341 ACKSPQPDPVDTPAST---KQRPKRNLRKADVEEEFLALRKRTPSA--GKAMDTPK-PAV 2394
K P + PA T K PK E K P+ G A TPK PA
Sbjct: 708 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAP 767
Query: 2395 SDEKNINTFVETPVQKLDLLGNLPGSKRQPQ--TPKEKAEALEDLVGFKELFQTPGHTEE 2452
+ K TP G P + ++P TPK+ A KEL T
Sbjct: 768 TTPKE--PAPTTPK------GTAPTTLKEPAPTTPKKPAP--------KELAPTTTKGPT 811
Query: 2453 SMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTH 2512
S T DK + K P + K + + P VS T T E T H
Sbjct: 812 STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK-EPTTIH 870
Query: 2513 TEPTGDSKSI------KAFKESPKQILDPAASVTGSRRQLRTRKEKARALE-DLVDFKEL 2565
P + + KA + SPK+ P + + T K + E DL E
Sbjct: 871 KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 930
Query: 2566 FSA-PGHTEESMTI-DKNTKIPCKSPPPELTDTAT------------STKRCPKTRPRKE 2611
+A P T+E+ T +K T+ + ++T T T +T PK K+
Sbjct: 931 TTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKK 990
Query: 2612 VKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPKE 2671
+ + +T+ A+ + K K A KKP ++ + R R PK
Sbjct: 991 TITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK--APKKPTSTKKPKTMPRVRKPKT 1048
Query: 2672 KAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTK 2721
P + + EL+ TS + L + T P ++P ++V+ ++
Sbjct: 1049 TPTPRKMTSTMPELNPTSRIAEAML---QTTTRPNQTPNSKLVEVNPKSE 1095
Score = 97.4 bits (241), Expect = 2e-19
Identities = 266/1125 (23%), Positives = 376/1125 (33%), Gaps = 170/1125 (15%)
Query: 800 PTSESFGGNVFFSAQNAAKQPSDKCSASPPLRRQCIRENGNVAKTPRNTYKMTS-LETKT 858
P ESF V N PS K + P Q I+ + P N K +E++
Sbjct: 98 PDYESFCAEV----HNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEE 153
Query: 859 SDTETEPSKTVSTANRSGRSTEFRNIQKLPVESKSEETNTEIVECILKRGQKATLLQQRR 918
E S+ +++ S S+ I+K+ SK+ N E+ + + + K +
Sbjct: 154 ITEEHSVSENQESSSSSSSSSSSSTIRKIK-SSKNSAANRELQKKLKVKDNK------KN 206
Query: 919 EGEMKEIERPFETYKENIELKENDEKMKAMKRSRTWGQKCAPMSDLTDLKSL-------P 971
+ K +P + L D K+ S T K + +T K + P
Sbjct: 207 RTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPP 266
Query: 972 DTELMKDTARGQNLLQTQDHAKAPKSEKGKIT--KMPCQSLQPEPINTPTHTKQQLKAS- 1028
+++ K+T+ N T + + + K T K S + T K S
Sbjct: 267 NSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 326
Query: 1029 -LGKVGVKEELLAVGKFTRTSGE-TTHTHREPAG---DGKSIRTFKESPKQILDPAARVT 1083
L K K E G T E T T +EPA + T K +P +PA T
Sbjct: 327 VLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTT 386
Query: 1084 GMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACKSPPPESVDTPTST 1143
K P TPKE A + + P P+ TTK + P + PT+
Sbjct: 387 --KSAPTTPKEPAPTTT---------KEPAPTTPKEPAPTTTK---EPAPTTTKSAPTTP 432
Query: 1144 KQ----WPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLD 1199
K+ PK+ E ++ TP+ TPK K+ P +
Sbjct: 433 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPT------TPKEPAPTTKE-----PAPTTPKE 481
Query: 1200 LAGTLPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPV 1259
A T P K TPKE P T A TTK P SP +
Sbjct: 482 PAPTAP-KKPAPTTPKE-----------------PAPTTPKEPAPTTTKEP--SPTTPKE 521
Query: 1260 DTPTSTKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQK 1319
PT+TK P + A + SA P P+ +E TP +
Sbjct: 522 PAPTTTKSAPTTTKEPAPTTTK---------SAPTTPKEPSPTTTKEP----APTTPKEP 568
Query: 1320 LDLTENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPE 1379
T K P TPKE P T A TTK P ++P E
Sbjct: 569 APTTP----KKPAPTTPKE-----------------PAPTTPKEPAPTTTKKPAPTTPKE 607
Query: 1380 SADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGE----TTHTDKVP-GGEDKSINAF 1434
A T T P TP + E KL T+ E TT + P E+ +
Sbjct: 608 PAPT-TPKETAPTTPKKLTPTTPE-----KLAPTTPEKPAPTTPEELAPTTPEEPTPTTP 661
Query: 1435 RETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIAC 1494
E A AA T + P T ++ P KE T PTT + T
Sbjct: 662 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP----KEPAPTTPKETAPTTPKGTAPTTL 717
Query: 1495 RSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSA--GKAMHTPK-PAVSGEKNI 1551
+ +P P T KP K E K P+ G A TPK PA +
Sbjct: 718 K-EPAPT---TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT----- 768
Query: 1552 YAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTA 1611
TP + T T T KE A KEL T S T+DK A
Sbjct: 769 -----TPKEPAPTTPKGTAP----TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA 819
Query: 1612 KVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGK 1671
K + P K PA + + V T T+ E T H P
Sbjct: 820 PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPT-TTKEPTTIHKSPDESTP 878
Query: 1672 SM------KAFMESPKQI-LDSAASLTGSKRQLRTPKGKSEVPEDLAGFIE-LFQTPSHT 1723
+ KA SPK+ + + + +K ++ T DL E P T
Sbjct: 879 ELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 938
Query: 1724 KE-SMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAM 1782
KE + T EKTT+ A+ + T T K + K T + K+T + + M
Sbjct: 939 KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIM 998
Query: 1783 HTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTP 1842
+ P+ + KD T K +P P + T+K K + R+ TP
Sbjct: 999 NKPE-ETAKPKDRATNSKATTPKPQKPTKAP--KKPTSTKKPKT-----MPRVRKPKTTP 1050
Query: 1843 CTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVE 1887
T K T + +P S A+ T RP ++ VE
Sbjct: 1051 ------TPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVE 1089
Score = 80.5 bits (197), Expect = 3e-14
Identities = 219/1040 (21%), Positives = 330/1040 (31%), Gaps = 154/1040 (14%)
Query: 1980 SCKSPQPDPVK------TPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETA 2033
S K+P P T S K K KV EE+ +++ ++ + ++
Sbjct: 116 SKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSS 175
Query: 2034 GDG-KSIKAFKESAK--------QMLDPANYGTGMERWPRTPK-EEAQSLEDLAGFKELF 2083
+ IK+ K SA ++ D T + P+ P +EA S D FK
Sbjct: 176 SSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFK--V 233
Query: 2084 QTPD-----HTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALK 2138
TPD H + ST+ TT A P S+ + T + + K VE
Sbjct: 234 TTPDTSTTQHNKVSTSPKITT--AKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTT 291
Query: 2139 QLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTG--SKRQPRTPKGKAQPLEDLAG 2196
QT+ K K +T+ + L P + V + + T KG A L
Sbjct: 292 TNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPA-----LTT 346
Query: 2197 LKELFQTPICTDKPTTHEKTTKIACRSPQPDPVG----TPTIFKPQSKRSLRKADVEEES 2252
KE PTT ++ + P P + TP P + +S E
Sbjct: 347 PKE--------PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAP 398
Query: 2253 LALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQA 2312
++ P+ K P P E P + P K P TPKE A
Sbjct: 399 TTTKEPAPTTPKE---PAPTTTKEPAPTTTKSAPTTPKE-PAPTTPKKPAPTTPKEPAPT 454
Query: 2313 LEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEE 2372
TP PTT ++ K P P PA T PK+ E
Sbjct: 455 ------------TPKEPTPTTPKEPAPTT-KEPAPTTPKEPAPTA--PKKPAPTTPKEPA 499
Query: 2373 FLALRKRTPSAGK--AMDTPK-PAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKE 2429
++ P+ K + TPK PA + K+ T + P +K P TPKE
Sbjct: 500 PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT--------TKSAPTTPKE 551
Query: 2430 KAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKV 2489
+ KE T T K + K P P + K + + P
Sbjct: 552 PSPTTT-----KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP- 605
Query: 2490 DMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTR 2549
+EP + + + TT PT K E P + T T
Sbjct: 606 ---KEPAPTTP--KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTT 660
Query: 2550 KEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTA------TSTKRC 2603
E+ P T K P + P E T T+ K
Sbjct: 661 PEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 720
Query: 2604 PKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSR 2663
T P+K +EL+ T KEP S KP P P
Sbjct: 721 APTTPKKPAPKELAPT------------TTKEPTS----------TTCDKPAPTT--PKG 756
Query: 2664 RRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRH 2723
P PKE A T T+ T + A P + P E+ TT
Sbjct: 757 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE----PAPTTPKKPAPKELAPTT------ 806
Query: 2724 LRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGS 2783
T+ ++P+ +T+ TT + P K E+ T + ++ T +
Sbjct: 807 --TKGPTSTTSDKPAPTTPKETA-PTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTT 863
Query: 2784 RRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSS----- 2838
+ + ++ +L+ P A TTK P + PE+ TA
Sbjct: 864 KEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERD 923
Query: 2839 -KRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFK-------QPAK 2890
+ P T ++ +E + T S T T + + T FK A
Sbjct: 924 LRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP 983
Query: 2891 RKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTP 2950
+ + I + P+E A+P + + + + P T APK+
Sbjct: 984 KVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKP-----------QKPTKAPKKPT 1032
Query: 2951 DSGKPLKISRRVLRAPKVEP 2970
+ KP + R +R PK P
Sbjct: 1033 STKKPKTMPR--VRKPKTTP 1050
Score = 66.6 bits (161), Expect = 4e-10
Identities = 229/1059 (21%), Positives = 337/1059 (31%), Gaps = 136/1059 (12%)
Query: 1368 TTKMPCESSPPESADTPT---STRRQPKTP--------LEKRDVQKELSALKKLTQTSGE 1416
T+ + +PP S + T +T+R PK P +E ++ +E S + +S
Sbjct: 111 TSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSS 170
Query: 1417 TTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQP---LEDLAGL--- 1470
++ + + KS A ++L V +K++ +TK+K P + D AG
Sbjct: 171 SSSSSSSTIRKIKSSK--NSAANRELQKKLKVKDNKKN-RTKKKPTPKPPVVDEAGSGLD 227
Query: 1471 KELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLR-KVDVEEEFFALRK 1529
F+ T H K + + P++ S P S S + V +E K
Sbjct: 228 NGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETK 287
Query: 1530 RTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALED-- 1587
T + K T EK A ++K ++L + + L P KA+
Sbjct: 288 ETTTTNKQTSTD----GKEKTTSAKETQSIEKTS-AKDLAPTSKVLAKPTPKAETTTKGP 342
Query: 1588 -LAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEEL 1646
L KE T S T + KS+ P K PA + + + K
Sbjct: 343 ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTP-KEPAPTTTKSAPTTPK------- 394
Query: 1647 LAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGKSEV 1706
TT PT + + P +A T + TPK +
Sbjct: 395 --------EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 446
Query: 1707 -PEDLAGFIELFQTPSHTKESMTNEK----TTKVSYRASQPDLVDTPTSSKPQPKRSLRK 1761
P++ A TP+ KE K TT + P T +P P
Sbjct: 447 TPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 506
Query: 1762 ADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQT 1821
A T ++ +P+ K +PA K T P + T
Sbjct: 507 APTTT-----KEPSPTTPK-----EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 556
Query: 1822 RKEKAQALEELTGFRELFQTPCTDNPTTDEK---TTKKILCKSPQSDPADTPTNTKQ--- 1875
KE A TP PTT +K TT K + +PA PT TK+
Sbjct: 557 TKEPAPT------------TPKEPAPTTPKKPAPTTPKEPAPTTPKEPA--PTTTKKPAP 602
Query: 1876 -RPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLGNL 1934
PK E +KLTP+ + + A EK T TP E L
Sbjct: 603 TTPKEPAPTTPKETAPTTPKKLTPTTPEKL----APTTPEKPAPT---TPEE----LAPT 651
Query: 1935 PGSKRRPQTPKEKAKALEDLAGF---KELFQTPGHTEESMTDDKITEVSCKSPQPDPVK- 1990
+ P TP+E A A KE T T + + K P K
Sbjct: 652 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 711
Query: 1991 -TPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQM 2049
PT+ K+ + K KE K + + T T G + KE A
Sbjct: 712 TAPTTLKEPAPTTPKKPAPKELAPTTTK--EPTSTTCDKPAPTTPKGTAPTTPKEPAPTT 769
Query: 2050 LDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPE 2109
T P T KE A + KEL T STT DK K P
Sbjct: 770 PKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 829
Query: 2110 SMDTPTST---RRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQ 2166
+ P T + P TP E+S + T K P + ++ E +
Sbjct: 830 TPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSA--EPTPK 887
Query: 2167 KLDPAASVTG---SKRQPRTPKGKAQPLEDLAGLKELFQTPICT--------DKPTTHEK 2215
L+ + G +K T +D ++L TP T + TT EK
Sbjct: 888 ALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK 947
Query: 2216 TTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGD 2275
TT+ + T T K + K + K+T + + M+ P+
Sbjct: 948 TTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEET-AK 1006
Query: 2276 EKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDE 2335
KD K P P K+ T K K P KP T
Sbjct: 1007 PKDRATNSKATTPKPQKPTKAP--KKPTSTKKPKTM--------------PRVRKPKTTP 1050
Query: 2336 KTTKIACKSPQPDPVDTPA----STKQRPKRNLRKADVE 2370
K+ P+ +P A T RP + VE
Sbjct: 1051 TPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVE 1089
Score = 50.8 bits (120), Expect = 2e-05
Identities = 99/498 (19%), Positives = 164/498 (32%), Gaps = 53/498 (10%)
Query: 2418 PGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRS 2477
P SK+ P P ++ ++ T++ + ++ITE S ES +S S
Sbjct: 114 PSSKKAPP-PSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSS 172
Query: 2478 SKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAA 2537
S I +K S + Q + + K+ K +PK P
Sbjct: 173 SSSSSTIRKIK----------SSKNSAANRELQKKLKVKDNKKNRTKKKPTPKP---PVV 219
Query: 2538 SVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESM--TIDKNTKIPCKSPPPELTD 2595
GS D DFK T+ + T K T +P P L
Sbjct: 220 DEAGSGL-------------DNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPP 266
Query: 2596 TATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTH-KEPASGDEGIKVLKQRAKKKP 2654
+ ++K T V +E + + T T+ + T T KE + + + +++ + K
Sbjct: 267 NSDTSKETSLT-----VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 321
Query: 2655 NPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVV 2714
P + ++ P+A P T E + T + A+ P E P +
Sbjct: 322 APTSKVLAKPTPKAETTTKGP-----ALTTPKEPTPTTPKE----PASTTPKEPTPTTIK 372
Query: 2715 DTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTP 2774
+ K T + + A T+ TT + P + +SA TP
Sbjct: 373 SAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTP 432
Query: 2775 APAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDT 2834
A T + P P+E A K+P +E TTK P ++P+ E
Sbjct: 433 KEPAPTTPKKPAPTTPKEPAPTTP-----KEPTPTTPKEPA---PTTKEPAPTTPK-EPA 483
Query: 2835 ATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLD 2894
T+ K+ T ++ T+ TT + P K+PA
Sbjct: 484 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 543
Query: 2895 AEDVIGSRRQPRAPKEKA 2912
+ P KE A
Sbjct: 544 SAPTTPKEPSPTTTKEPA 561
Score = 38.9 bits (89), Expect = 0.084
Identities = 102/461 (22%), Positives = 150/461 (32%), Gaps = 88/461 (19%)
Query: 994 APKSEKGKITKMPCQSLQPEPI-NTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETT 1052
APK TK P + +P TP T KE K G
Sbjct: 729 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK-----GTAP 783
Query: 1053 HTHREPAGDGKSIRTFKESPKQILDPAAR----VTGMKKWPRTPKEEAQSLEDLAGFKEL 1108
T +EPA K +PK++ + T K P TPKE A +
Sbjct: 784 TTLKEPAPTTPK----KPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP-------- 831
Query: 1109 FQTPGPSEESMTDEKTTKIACKSPPPES--VDTPTSTKQWPKRSLRKADVEEEFLALRKL 1166
+ P P+ T +K ++PPP + V TPT+TK+ ++ K+ E
Sbjct: 832 -KEPAPT----TPKKPAPTTPETPPPTTSEVSTPTTTKE--PTTIHKSPDES-------- 876
Query: 1167 TPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAG 1226
TP A TPK K+ G P K A T E +D
Sbjct: 877 TPELS-AEPTPKALENSPKE----PGVPTTKTPAA-----------TKPEMTTTAKDKTT 920
Query: 1227 FKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACR 1286
++L TP E AA K TK +T T+T++ + I + +
Sbjct: 921 ERDLRTTP---ETTTAAPKMTK-----------ETATTTEKTTESKITATTTQVTSTTTQ 966
Query: 1287 NLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDL 1346
+ P + T T K+ T+ + P+E A+ +
Sbjct: 967 DTTPFKITTLKTT---------------TLAPKVTTTKKTITTTEIMNKPEETAKPKDRA 1011
Query: 1347 TGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSA 1406
T K P +A +TK P T + R+ T E + A
Sbjct: 1012 TNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEA 1071
Query: 1407 LKKLTQTSGETTHTDKV---PGGEDKSINAFRETAKQKLDP 1444
+ + T +T ++ V P ED A ET L P
Sbjct: 1072 MLQTTTRPNQTPNSKLVEVNPKSEDAG-GAEGETPHMLLRP 1111
Score = 35.0 bits (79), Expect = 1.2
Identities = 57/264 (21%), Positives = 97/264 (36%), Gaps = 27/264 (10%)
Query: 2996 FKRGGGKDGSVTGTKRLRCMPAPEEIVEEL------PASKKQRVAPRARGKSSEPVVIMK 3049
F+RG D K +C P E E+ P+SKK AP G S K
Sbjct: 78 FERGRECDCDAQCKKYDKCCPDYESFCAEVHNPTSPPSSKK---APPPSGASQTIKSTTK 134
Query: 3050 RSLRTSAKR-----IEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQ 3104
RS + K+ IE E + + N+E S + ++R + +K A +
Sbjct: 135 RSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSS--SSSSSTIRKIKSSKNSAANR 192
Query: 3105 ITEVFVLAERIEINRNEKKPMKTSPEMDIQNP--DDGARK-PIPRDKVTENKRCLRSARQ 3161
+ + + + NR +KKP P +D D+G K P T++ + S +
Sbjct: 193 ELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKI 252
Query: 3162 NESS----QPKVAEESGGQKSAKVLMQN----QKGKGEAGNSDSMCLRSRKTKSQPAAST 3213
+ +P + S K + + + + N + KT S +
Sbjct: 253 TTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQS 312
Query: 3214 LESKSVQRVTRSVKRCAENPKKAE 3237
+E S + + + K A+ KAE
Sbjct: 313 IEKTSAKDLAPTSKVLAKPTPKAE 336
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 93.6 bits (231), Expect = 3e-18
Identities = 220/978 (22%), Positives = 320/978 (32%), Gaps = 127/978 (12%)
Query: 1780 KAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELF 1839
K TPKP V +E G+ + D P ++ T+ K ++T + +
Sbjct: 75 KKKPTPKPPVVDEA------GSGLDNGDFKVTTPDTST---TQHNKVSTSPKITTAKPIN 125
Query: 1840 QTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRK---- 1895
P + K T + K + +T T KQ +K +E + K
Sbjct: 126 PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 185
Query: 1896 -LTPSAGK-AMHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKAKALED 1953
L P++ A TPKA + T TP E P TPKE A
Sbjct: 186 DLAPTSKVLAKPTPKAETTTKGPALT---TPKEPT------------PTTPKEPAST--- 227
Query: 1954 LAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKT-PTSSKQRLKISLGKVGVKEEV 2012
TP E + T K + K P P K+ PT+ K+ + +
Sbjct: 228 ---------TP--KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 276
Query: 2013 LPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQS 2072
P T+ TT T + K+ A T E P TPKE A +
Sbjct: 277 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 336
Query: 2073 LEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVE 2132
KE T T K K P P + P T + +P + E
Sbjct: 337 T------KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK---E 387
Query: 2133 ELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLE 2192
+ TT + P +E + A T + P TPK A
Sbjct: 388 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 447
Query: 2193 DLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEES 2252
KE T PTT +K + P P TP P + + L E+
Sbjct: 448 -----KEPAPTTPKEPAPTTTKKPAPTTPKEPAPT---TPKETAPTTPKKLTPTTPEK-- 497
Query: 2253 LALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQA 2312
L TP + P P +E + P P TPKE A
Sbjct: 498 --LAPTTP------EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 549
Query: 2313 LEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPAST---KQRPKRNLRKADV 2369
+ TP PTT ++T K P + PA T K PK
Sbjct: 550 TPK----EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 605
Query: 2370 EEEFLALRKRTPSA--GKAMDTPK-PAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQ- 2425
E K P+ G A TPK PA + K TP G P + ++P
Sbjct: 606 EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE--PAPTTPK------GTAPTTLKEPAP 657
Query: 2426 -TPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKI 2484
TPK+ A KEL T S T DK + K P + K + +
Sbjct: 658 TTPKKPAP--------KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA 709
Query: 2485 PLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSI------KAFKESPKQILDPAAS 2538
P VS T T E T H P + + KA + SPK+ P
Sbjct: 710 PTTPETPPPTTSEVSTPTTTK-EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTK 768
Query: 2539 VTGSRRQLRTRKEKARALE-DLVDFKELFSA-PGHTEESMTI-DKNTKIPCKSPPPELTD 2595
+ + T K + E DL E +A P T+E+ T +K T+ + ++T
Sbjct: 769 TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTS 828
Query: 2596 TAT------------STKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGI 2643
T T +T PK K+ + + +T+ A+ +
Sbjct: 829 TTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQ 888
Query: 2644 KVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATK 2703
K K A KKP ++ + R R PK P + + EL+ TS + L + T
Sbjct: 889 KPTK--APKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAML---QTTT 943
Query: 2704 IPCESPPLEVVDTTASTK 2721
P ++P ++V+ ++
Sbjct: 944 RPNQTPNSKLVEVNPKSE 961
Score = 87.8 bits (216), Expect = 2e-16
Identities = 245/1025 (23%), Positives = 342/1025 (33%), Gaps = 137/1025 (13%)
Query: 913 LLQQRREGEMKEIERPFETYKENIELKENDEKMKAMKRSRTWGQKCAPMSD----LTDLK 968
++QQ E+ R FE+++ E + + K K + CA + D T K
Sbjct: 18 VIQQVSSQELSCKGRCFESFERGRECDCDAQCKKYDKCCPDYESFCAEVKDNKKNRTKKK 77
Query: 969 SLPDTELMKDTARGQNL---------LQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPT 1019
P ++ + G + T H K S K K + P P P
Sbjct: 78 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAK----PINPRPSLPPN 133
Query: 1020 HTKQQLKASLGKVGVKEELLAVGKFTRT-SGETTHTHREPAGDGKSIRTFKESPKQILDP 1078
KE L V K T + ETT T+++ + DGK T + + I
Sbjct: 134 SDTS-----------KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 182
Query: 1079 AAR---VTGMKKWPRTPKEEAQSL-EDLAGFKELFQTPGPSEESMTDEKTTKIACKSPPP 1134
+A+ T TPK E + L KE T S T ++ T KS P
Sbjct: 183 SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPT 242
Query: 1135 ESVD-TPTSTKQWPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMGT 1193
+ PT+TK P A + A TP T +PA K
Sbjct: 243 TPKEPAPTTTKSAPTTPKEPAPTTTKEPA--PTTPKEPAPTTTKEPAPTTTK------SA 294
Query: 1194 PVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDS 1253
P + A T P K TPKE A KE TP +E TTK P +
Sbjct: 295 PTTPKEPAPTTP-KKPAPTTPKEPAPTTP-----KE--PTPTTPKE---PAPTTKEPAPT 343
Query: 1254 PQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFV 1313
+P T PK+ E + P+ K P P+ +E
Sbjct: 344 TPKEPAPT------APKKPAPTTPKEPAPTTPKEPAPTTTK---EPSPTTPKEPAPTTTK 394
Query: 1314 GTPVQKLDLTENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPC 1373
P + T +K P TPKE + T KE P T A T K P
Sbjct: 395 SAPTTTKEPAP--TTTKSAPTTPKEPSP-----TTTKE----PAPTTPKEPAPTTPKKPA 443
Query: 1374 ESSPPESADT------PTSTRR----QPKTPLEKRDVQKELSALKKLTQTSGE----TTH 1419
++P E A T PT+T++ PK P + + KKLT T+ E TT
Sbjct: 444 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP 503
Query: 1420 TDKVPGGEDKSINAFRE----TAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGL-KELF 1474
P ++ E T ++ P + PK P E KE
Sbjct: 504 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 563
Query: 1475 QTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSA 1534
T PTT + T + +P P T KP K E K P+
Sbjct: 564 PTTPKETAPTTPKGTAPTTLK-EPAPT---TPKKPAPKELAPTTTKEPTSTTCDKPAPTT 619
Query: 1535 --GKAMHTPK-PAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGF 1591
G A TPK PA + TP + T T T KE A
Sbjct: 620 PKGTAPTTPKEPAPT----------TPKEPAPTTPKGTAP----TTLKEPAPTTPKKPAP 665
Query: 1592 KELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGK 1651
KEL T S T+DK A K + P K PA + + V
Sbjct: 666 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 725
Query: 1652 LTQTSGETTHTHTEPTGDGKSM------KAFMESPKQI-LDSAASLTGSKRQLRTPKGKS 1704
T T+ E T H P + KA SPK+ + + + +K ++ T
Sbjct: 726 PT-TTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDK 784
Query: 1705 EVPEDLAGFIE-LFQTPSHTKE-SMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKA 1762
DL E P TKE + T EKTT+ A+ + T T K + K
Sbjct: 785 TTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKT 844
Query: 1763 DTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTR 1822
T + K+T + + M+ P+ + KD T K +P P + T+
Sbjct: 845 TTLAPKVTTTKKTITTTEIMNKPE-ETAKPKDRATNSKATTPKPQKPTKAP--KKPTSTK 901
Query: 1823 KEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLK 1882
K K + R+ TP T K T + +P S A+ T RP ++
Sbjct: 902 KPKT-----MPRVRKPKTTP------TPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPN 950
Query: 1883 KADVE 1887
VE
Sbjct: 951 SKLVE 955
Score = 78.2 bits (191), Expect = 1e-13
Identities = 201/943 (21%), Positives = 296/943 (31%), Gaps = 142/943 (15%)
Query: 2065 TPK----EEAQSLEDLAGFKELFQTPD-----HTEESTTDDKTTKIACKSPPPESMDTPT 2115
TPK +EA S D FK TPD H + ST+ TT A P S+ +
Sbjct: 79 TPKPPVVDEAGSGLDNGDFK--VTTPDTSTTQHNKVSTSPKITT--AKPINPRPSLPPNS 134
Query: 2116 STRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVT 2175
T + + K VE QT+ K K +T+ + L P + V
Sbjct: 135 DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL 194
Query: 2176 G--SKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVG--- 2230
+ + T KG A L KE PTT ++ + P P +
Sbjct: 195 AKPTPKAETTTKGPA-----LTTPKE--------PTPTTPKEPASTTPKEPTPTTIKSAP 241
Query: 2231 -TPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQK 2289
TP P + +S E ++ P+ K P P E P
Sbjct: 242 TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE---PAPTTTKEPAPTTTKSAPTTP 298
Query: 2290 LDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDP 2349
+ P K P TPKE A TP PTT ++ K P P
Sbjct: 299 KE-PAPTTPKKPAPTTPKEPAPT------------TPKEPTPTTPKEPAPTT-KEPAPTT 344
Query: 2350 VDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGK--AMDTPK-PAVSDEKNINTFVET 2406
PA T PK+ E ++ P+ K + TPK PA + K+ T +
Sbjct: 345 PKEPAPTA--PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 402
Query: 2407 PVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKS 2466
P +K P TPKE + KE T T K + K
Sbjct: 403 PAPTT--------TKSAPTTPKEPSPTTT-----KEPAPTTPKEPAPTTPKKPAPTTPKE 449
Query: 2467 PQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFK 2526
P P + K + + P +EP + + + TT PT K
Sbjct: 450 PAPTTPKEPAPTTTKKPAPTTP----KEPAPTTP--KETAPTTPKKLTPTTPEKLAPTTP 503
Query: 2527 ESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPC 2586
E P + T T E+ P T K P
Sbjct: 504 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 563
Query: 2587 KSPPPELTDTA------TSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGD 2640
+ P E T T+ K T P+K +EL+ T KEP S
Sbjct: 564 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT------------TTKEPTS-- 609
Query: 2641 EGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGK 2700
KP P P P PKE A T T+ T +
Sbjct: 610 --------TTCDKPAPTT--PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE----P 655
Query: 2701 ATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGED 2760
A P + P E+ TT T+ ++P+ +T+ TT + P
Sbjct: 656 APTTPKKPAPKELAPTT--------TKGPTSTTSDKPAPTTPKETA-PTTPKEPAPTTPK 706
Query: 2761 KGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKT 2820
K E+ T + ++ T ++ + ++ +L+ P A T
Sbjct: 707 KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPT 766
Query: 2821 TKIPCKSSPELEDTATSS------KRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKE 2874
TK P + PE+ TA + P T ++ +E + T S T T +
Sbjct: 767 TKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 826
Query: 2875 PVGEGKGTKAFK-------QPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQT 2927
+ T FK A + + I + P+E A+P + + + +
Sbjct: 827 TSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPK 886
Query: 2928 PGHTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEP 2970
P T APK+ + KP + R +R PK P
Sbjct: 887 P-----------QKPTKAPKKPTSTKKPKTMPR--VRKPKTTP 916
Score = 66.2 bits (160), Expect = 5e-10
Identities = 189/834 (22%), Positives = 263/834 (31%), Gaps = 139/834 (16%)
Query: 1238 EELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMPSA----- 1292
E + K T + ++ ++ + TST + K + K E + ++L P++
Sbjct: 139 ETSLTVNKETTV--ETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 196
Query: 1293 ----------GKAMHTPK-PSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQ 1341
G A+ TPK P+ K+ P T K P TPKE A
Sbjct: 197 PTPKAETTTKGPALTTPKEPTPTTPKE-------PASTTPKEPTPTTIKSAPTTPKEPAP 249
Query: 1342 ALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADT------PTSTRRQPKTPL 1395
T K TP A TTK P ++P E A T PT+T+ P TP
Sbjct: 250 -----TTTKSAPTTPKEP-----APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 299
Query: 1396 EKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHP 1455
E + A + TT + P + +E A A K P
Sbjct: 300 EPAPTTPKKPA-PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 358
Query: 1456 KTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEK----TTKIACRSQPDPVDTPTSSKPQS 1511
T ++ P KE T PTT ++ TTK A + +P T T S P +
Sbjct: 359 TTPKEPAPTTP----KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 414
Query: 1512 KRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGS 1571
+ +E TP KPA + K TP + T
Sbjct: 415 PKEPSPTTTKEP----APTTPKEPAPTTPKKPAPTTPKE--PAPTTPKEPAPTTT----K 464
Query: 1572 KRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKN--PASS 1629
K TPKE A KE T T +K A + P + P +
Sbjct: 465 KPAPTTPKEPAPTTP-----KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 519
Query: 1630 KRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAAS 1689
+ T+ + A + TT PT + + +
Sbjct: 520 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 579
Query: 1690 LTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKE--SMTNEKTTKVSYRASQPDLVDT 1747
T K T K P++LA P+ TKE S T +K + + + P
Sbjct: 580 PTTLKEPAPTTP-KKPAPKELA--------PTTTKEPTSTTCDKPAPTTPKGTAP----- 625
Query: 1748 PTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLD 1807
T +P P A T + A T A TPK +E T G D
Sbjct: 626 TTPKEPAPTTPKEPAPTTPKGTA---PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 682
Query: 1808 QPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPA 1867
+P T KE A TP PTT E P +
Sbjct: 683 KPAPTTPKETAPTTPKEPAPT------------TPKKPAPTTPE-------TPPPTTSEV 723
Query: 1868 DTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEK 1927
TPT TK+ P K D + TP A TPKA K+ G P K
Sbjct: 724 STPTTTKE-PTTIHKSPD---------ESTPEL-SAEPTPKALENSPKE----PGVPTTK 768
Query: 1928 LDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHT--------EESMTDDKITEV 1979
P + + T K K E ++L TP T E + T +K TE
Sbjct: 769 ------TPAATKPEMTTTAKDKTTE-----RDLRTTPETTTAAPKMTKETATTTEKTTES 817
Query: 1980 SCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETA 2033
+ T T KI+ K + K T T+ + ETA
Sbjct: 818 KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETA 871
Score = 55.8 bits (133), Expect = 7e-07
Identities = 212/970 (21%), Positives = 302/970 (31%), Gaps = 123/970 (12%)
Query: 1446 ASVTGSKRHPKTKEKAQP---LEDLAGL---KELFQTPVCTDKPTTHEKTTKIACRSQPD 1499
A V +K++ +TK+K P + D AG F+ T H K + +
Sbjct: 64 AEVKDNKKN-RTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAK 122
Query: 1500 PVDTPTSSKPQSKRSLR-KVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTP 1558
P++ S P S S + V +E K T + K T EK A
Sbjct: 123 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTD----GKEKTTSAKETQS 178
Query: 1559 VQKLDLTENLTGSKRRLQTPKEKAQALED---LAGFKELFQTRGHTEESMTNDKTAKVAC 1615
++K ++L + + L P KA+ L KE T S T +
Sbjct: 179 IEKTS-AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI 237
Query: 1616 KSSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKA 1675
KS+ P K PA + + + K TT PT +
Sbjct: 238 KSAPTTP-KEPAPTTTKSAPTTPK---------------EPAPTTTKEPAPTTPKEPAPT 281
Query: 1676 FMESPKQILDSAASLTGSKRQLRTPKGKSEV-PEDLAGFIELFQTPSHTKESMTNEK--- 1731
+ P +A T + TPK + P++ A TP+ KE K
Sbjct: 282 TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 341
Query: 1732 -TTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVG 1790
TT + P T +P P A T ++ +P+ K +PA
Sbjct: 342 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT-----KEPSPTTPK-----EPAPT 391
Query: 1791 EEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTD 1850
K T P + T KE A TP PTT
Sbjct: 392 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT------------TPKEPAPTTP 439
Query: 1851 EK---TTKKILCKSPQSDPADTPTNTKQ----RPKRSLKKADVEEEFLAFRKLTPSAGKA 1903
+K TT K + +PA PT TK+ PK E +KLTP+ +
Sbjct: 440 KKPAPTTPKEPAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK 497
Query: 1904 MHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGF---KEL 1960
+ A EK T TP E L + P TP+E A A KE
Sbjct: 498 L----APTTPEKPAPT---TPEE----LAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 546
Query: 1961 FQTPGHTEESMTDDKITEVSCKSPQPDPVK--TPTSSKQRLKISLGKVGVKEEVLPVGKL 2018
T T + + K P K PT+ K+ + K KE K
Sbjct: 547 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK- 605
Query: 2019 TQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAG 2078
+ + T T G + KE A T P T KE A +
Sbjct: 606 -EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA 664
Query: 2079 FKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTST---RRRPKTPLGKRDIVEELS 2135
KEL T STT DK K P + P T + P TP E+S
Sbjct: 665 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 724
Query: 2136 ALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTG---SKRQPRTPKGKAQPLE 2192
+ T K P + ++ E + L+ + G +K T +
Sbjct: 725 TPTTTKEPTTIHKSPDESTPELSA--EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 782
Query: 2193 DLAGLKELFQTPICT--------DKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLR 2244
D ++L TP T + TT EKTT+ + T T K +
Sbjct: 783 DKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTL 842
Query: 2245 KADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQ 2304
K + K+T + + M+ P+ KD K P P K+
Sbjct: 843 KTTTLAPKVTTTKKTITTTEIMNKPEET-AKPKDRATNSKATTPKPQKPTKAP--KKPTS 899
Query: 2305 TPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPA----STKQRP 2360
T K K P KP T K+ P+ +P A T RP
Sbjct: 900 TKKPKTM--------------PRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRP 945
Query: 2361 KRNLRKADVE 2370
+ VE
Sbjct: 946 NQTPNSKLVE 955
Score = 38.9 bits (89), Expect = 0.084
Identities = 102/461 (22%), Positives = 150/461 (32%), Gaps = 88/461 (19%)
Query: 994 APKSEKGKITKMPCQSLQPEPI-NTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETT 1052
APK TK P + +P TP T KE K G
Sbjct: 595 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK-----GTAP 649
Query: 1053 HTHREPAGDGKSIRTFKESPKQILDPAAR----VTGMKKWPRTPKEEAQSLEDLAGFKEL 1108
T +EPA K +PK++ + T K P TPKE A +
Sbjct: 650 TTLKEPAPTTPK----KPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP-------- 697
Query: 1109 FQTPGPSEESMTDEKTTKIACKSPPPES--VDTPTSTKQWPKRSLRKADVEEEFLALRKL 1166
+ P P+ T +K ++PPP + V TPT+TK+ ++ K+ E
Sbjct: 698 -KEPAPT----TPKKPAPTTPETPPPTTSEVSTPTTTKE--PTTIHKSPDES-------- 742
Query: 1167 TPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAG 1226
TP A TPK K+ G P K A T E +D
Sbjct: 743 TPELS-AEPTPKALENSPKE----PGVPTTKTPAA-----------TKPEMTTTAKDKTT 786
Query: 1227 FKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACR 1286
++L TP E AA K TK +T T+T++ + I + +
Sbjct: 787 ERDLRTTP---ETTTAAPKMTK-----------ETATTTEKTTESKITATTTQVTSTTTQ 832
Query: 1287 NLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDL 1346
+ P + T T K+ T+ + P+E A+ +
Sbjct: 833 DTTPFKITTLKTT---------------TLAPKVTTTKKTITTTEIMNKPEETAKPKDRA 877
Query: 1347 TGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSA 1406
T K P +A +TK P T + R+ T E + A
Sbjct: 878 TNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEA 937
Query: 1407 LKKLTQTSGETTHTDKV---PGGEDKSINAFRETAKQKLDP 1444
+ + T +T ++ V P ED A ET L P
Sbjct: 938 MLQTTTRPNQTPNSKLVEVNPKSEDAG-GAEGETPHMLLRP 977
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 93.6 bits (231), Expect = 3e-18
Identities = 220/978 (22%), Positives = 320/978 (32%), Gaps = 127/978 (12%)
Query: 1780 KAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELF 1839
K TPKP V +E G+ + D P ++ T+ K ++T + +
Sbjct: 116 KKKPTPKPPVVDEA------GSGLDNGDFKVTTPDTST---TQHNKVSTSPKITTAKPIN 166
Query: 1840 QTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRK---- 1895
P + K T + K + +T T KQ +K +E + K
Sbjct: 167 PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 226
Query: 1896 -LTPSAGK-AMHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKAKALED 1953
L P++ A TPKA + T TP E P TPKE A
Sbjct: 227 DLAPTSKVLAKPTPKAETTTKGPALT---TPKEPT------------PTTPKEPAST--- 268
Query: 1954 LAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKT-PTSSKQRLKISLGKVGVKEEV 2012
TP E + T K + K P P K+ PT+ K+ + +
Sbjct: 269 ---------TP--KEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK 317
Query: 2013 LPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQS 2072
P T+ TT T + K+ A T E P TPKE A +
Sbjct: 318 EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 377
Query: 2073 LEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVE 2132
KE T T K K P P + P T + +P + E
Sbjct: 378 T------KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK---E 428
Query: 2133 ELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLE 2192
+ TT + P +E + A T + P TPK A
Sbjct: 429 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 488
Query: 2193 DLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEES 2252
KE T PTT +K + P P TP P + + L E+
Sbjct: 489 -----KEPAPTTPKEPAPTTTKKPAPTTPKEPAPT---TPKETAPTTPKKLTPTTPEK-- 538
Query: 2253 LALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQA 2312
L TP + P P +E + P P TPKE A
Sbjct: 539 --LAPTTP------EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 590
Query: 2313 LEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPAST---KQRPKRNLRKADV 2369
+ TP PTT ++T K P + PA T K PK
Sbjct: 591 TPK----EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 646
Query: 2370 EEEFLALRKRTPSA--GKAMDTPK-PAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQ- 2425
E K P+ G A TPK PA + K TP G P + ++P
Sbjct: 647 EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE--PAPTTPK------GTAPTTLKEPAP 698
Query: 2426 -TPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKI 2484
TPK+ A KEL T S T DK + K P + K + +
Sbjct: 699 TTPKKPAP--------KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA 750
Query: 2485 PLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSI------KAFKESPKQILDPAAS 2538
P VS T T E T H P + + KA + SPK+ P
Sbjct: 751 PTTPETPPPTTSEVSTPTTTK-EPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTK 809
Query: 2539 VTGSRRQLRTRKEKARALE-DLVDFKELFSA-PGHTEESMTI-DKNTKIPCKSPPPELTD 2595
+ + T K + E DL E +A P T+E+ T +K T+ + ++T
Sbjct: 810 TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTS 869
Query: 2596 TAT------------STKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGI 2643
T T +T PK K+ + + +T+ A+ +
Sbjct: 870 TTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQ 929
Query: 2644 KVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATK 2703
K K A KKP ++ + R R PK P + + EL+ TS + L + T
Sbjct: 930 KPTK--APKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAML---QTTT 984
Query: 2704 IPCESPPLEVVDTTASTK 2721
P ++P ++V+ ++
Sbjct: 985 RPNQTPNSKLVEVNPKSE 1002
Score = 87.4 bits (215), Expect = 2e-16
Identities = 220/890 (24%), Positives = 302/890 (33%), Gaps = 109/890 (12%)
Query: 1035 KEELLAVGKFTRT-SGETTHTHREPAGDGKSIRTFKESPKQILDPAAR---VTGMKKWPR 1090
KE L V K T + ETT T+++ + DGK T + + I +A+ T
Sbjct: 179 KETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKP 238
Query: 1091 TPKEEAQSL-EDLAGFKELFQTPGPSEESMTDEKTTKIACKSPPPESVD-TPTSTKQWPK 1148
TPK E + L KE T S T ++ T KS P + PT+TK P
Sbjct: 239 TPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPT 298
Query: 1149 RSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSK 1208
A + A TP T +PA K P + A T P K
Sbjct: 299 TPKEPAPTTTKEPA--PTTPKEPAPTTTKEPAPTTTK------SAPTTPKEPAPTTP-KK 349
Query: 1209 RQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQR 1268
TPKE A KE TP +E TTK P + +P T
Sbjct: 350 PAPTTPKEPAPTTP-----KE--PTPTTPKE---PAPTTKEPAPTTPKEPAPT------A 393
Query: 1269 PKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTG 1328
PK+ E + P+ K P P+ +E P + T
Sbjct: 394 PKKPAPTTPKEPAPTTPKEPAPTTTK---EPSPTTPKEPAPTTTKSAPTTTKEPAP--TT 448
Query: 1329 SKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADT----- 1383
+K P TPKE + T KE P T A T K P ++P E A T
Sbjct: 449 TKSAPTTPKEPSP-----TTTKE----PAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 499
Query: 1384 -PTSTRR----QPKTPLEKRDVQKELSALKKLTQTSGE----TTHTDKVPGGEDKSINAF 1434
PT+T++ PK P + + KKLT T+ E TT P ++
Sbjct: 500 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTT 559
Query: 1435 RE----TAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGL-KELFQTPVCTDKPTTHEKT 1489
E T ++ P + PK P E KE T PTT + T
Sbjct: 560 PEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGT 619
Query: 1490 TKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSA--GKAMHTPK-PAVS 1546
+ +P P T KP K E K P+ G A TPK PA +
Sbjct: 620 APTTLK-EPAPT---TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPT 675
Query: 1547 GEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMT 1606
TP + T T T KE A KEL T S T
Sbjct: 676 ----------TPKEPAPTTPKGTAP----TTLKEPAPTTPKKPAPKELAPTTTKGPTSTT 721
Query: 1607 NDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEP 1666
+DK A K + P K PA + + V T T+ E T H P
Sbjct: 722 SDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPT-TTKEPTTIHKSP 780
Query: 1667 TGDGKSM------KAFMESPKQI-LDSAASLTGSKRQLRTPKGKSEVPEDLAGFIE-LFQ 1718
+ KA SPK+ + + + +K ++ T DL E
Sbjct: 781 DESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTA 840
Query: 1719 TPSHTKE-SMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPS 1777
P TKE + T EKTT+ A+ + T T K + K T + K+T +
Sbjct: 841 APKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTIT 900
Query: 1778 AGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRE 1837
+ M+ P+ + KD T K +P P + T+K K + R+
Sbjct: 901 TTEIMNKPE-ETAKPKDRATNSKATTPKPQKPTKAP--KKPTSTKKPKT-----MPRVRK 952
Query: 1838 LFQTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVE 1887
TP T K T + +P S A+ T RP ++ VE
Sbjct: 953 PKTTP------TPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVE 996
Score = 78.2 bits (191), Expect = 1e-13
Identities = 201/943 (21%), Positives = 296/943 (31%), Gaps = 142/943 (15%)
Query: 2065 TPK----EEAQSLEDLAGFKELFQTPD-----HTEESTTDDKTTKIACKSPPPESMDTPT 2115
TPK +EA S D FK TPD H + ST+ TT A P S+ +
Sbjct: 120 TPKPPVVDEAGSGLDNGDFK--VTTPDTSTTQHNKVSTSPKITT--AKPINPRPSLPPNS 175
Query: 2116 STRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVT 2175
T + + K VE QT+ K K +T+ + L P + V
Sbjct: 176 DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL 235
Query: 2176 G--SKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVG--- 2230
+ + T KG A L KE PTT ++ + P P +
Sbjct: 236 AKPTPKAETTTKGPA-----LTTPKE--------PTPTTPKEPASTTPKEPTPTTIKSAP 282
Query: 2231 -TPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQK 2289
TP P + +S E ++ P+ K P P E P
Sbjct: 283 TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKE---PAPTTTKEPAPTTTKSAPTTP 339
Query: 2290 LDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDP 2349
+ P K P TPKE A TP PTT ++ K P P
Sbjct: 340 KE-PAPTTPKKPAPTTPKEPAPT------------TPKEPTPTTPKEPAPTT-KEPAPTT 385
Query: 2350 VDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGK--AMDTPK-PAVSDEKNINTFVET 2406
PA T PK+ E ++ P+ K + TPK PA + K+ T +
Sbjct: 386 PKEPAPTA--PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 443
Query: 2407 PVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKS 2466
P +K P TPKE + KE T T K + K
Sbjct: 444 PAPTT--------TKSAPTTPKEPSPTTT-----KEPAPTTPKEPAPTTPKKPAPTTPKE 490
Query: 2467 PQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFK 2526
P P + K + + P +EP + + + TT PT K
Sbjct: 491 PAPTTPKEPAPTTTKKPAPTTP----KEPAPTTP--KETAPTTPKKLTPTTPEKLAPTTP 544
Query: 2527 ESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPC 2586
E P + T T E+ P T K P
Sbjct: 545 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 604
Query: 2587 KSPPPELTDTA------TSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGD 2640
+ P E T T+ K T P+K +EL+ T KEP S
Sbjct: 605 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT------------TTKEPTS-- 650
Query: 2641 EGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGK 2700
KP P P P PKE A T T+ T +
Sbjct: 651 --------TTCDKPAPTT--PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKE----P 696
Query: 2701 ATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGED 2760
A P + P E+ TT T+ ++P+ +T+ TT + P
Sbjct: 697 APTTPKKPAPKELAPTT--------TKGPTSTTSDKPAPTTPKETA-PTTPKEPAPTTPK 747
Query: 2761 KGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKT 2820
K E+ T + ++ T ++ + ++ +L+ P A T
Sbjct: 748 KPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPT 807
Query: 2821 TKIPCKSSPELEDTATSS------KRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKE 2874
TK P + PE+ TA + P T ++ +E + T S T T +
Sbjct: 808 TKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 867
Query: 2875 PVGEGKGTKAFK-------QPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQT 2927
+ T FK A + + I + P+E A+P + + + +
Sbjct: 868 TSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPK 927
Query: 2928 PGHTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEP 2970
P T APK+ + KP + R +R PK P
Sbjct: 928 P-----------QKPTKAPKKPTSTKKPKTMPR--VRKPKTTP 957
Score = 66.2 bits (160), Expect = 5e-10
Identities = 189/834 (22%), Positives = 263/834 (31%), Gaps = 139/834 (16%)
Query: 1238 EELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMPSA----- 1292
E + K T + ++ ++ + TST + K + K E + ++L P++
Sbjct: 180 ETSLTVNKETTV--ETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 237
Query: 1293 ----------GKAMHTPK-PSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQ 1341
G A+ TPK P+ K+ P T K P TPKE A
Sbjct: 238 PTPKAETTTKGPALTTPKEPTPTTPKE-------PASTTPKEPTPTTIKSAPTTPKEPAP 290
Query: 1342 ALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADT------PTSTRRQPKTPL 1395
T K TP A TTK P ++P E A T PT+T+ P TP
Sbjct: 291 -----TTTKSAPTTPKEP-----APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 340
Query: 1396 EKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHP 1455
E + A + TT + P + +E A A K P
Sbjct: 341 EPAPTTPKKPA-PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 399
Query: 1456 KTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEK----TTKIACRSQPDPVDTPTSSKPQS 1511
T ++ P KE T PTT ++ TTK A + +P T T S P +
Sbjct: 400 TTPKEPAPTTP----KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 455
Query: 1512 KRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGS 1571
+ +E TP KPA + K TP + T
Sbjct: 456 PKEPSPTTTKEP----APTTPKEPAPTTPKKPAPTTPKE--PAPTTPKEPAPTTT----K 505
Query: 1572 KRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKN--PASS 1629
K TPKE A KE T T +K A + P + P +
Sbjct: 506 KPAPTTPKEPAPTTP-----KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 560
Query: 1630 KRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAAS 1689
+ T+ + A + TT PT + + +
Sbjct: 561 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 620
Query: 1690 LTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKE--SMTNEKTTKVSYRASQPDLVDT 1747
T K T K P++LA P+ TKE S T +K + + + P
Sbjct: 621 PTTLKEPAPTTP-KKPAPKELA--------PTTTKEPTSTTCDKPAPTTPKGTAP----- 666
Query: 1748 PTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLD 1807
T +P P A T + A T A TPK +E T G D
Sbjct: 667 TTPKEPAPTTPKEPAPTTPKGTA---PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 723
Query: 1808 QPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPA 1867
+P T KE A TP PTT E P +
Sbjct: 724 KPAPTTPKETAPTTPKEPAPT------------TPKKPAPTTPE-------TPPPTTSEV 764
Query: 1868 DTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEK 1927
TPT TK+ P K D + TP A TPKA K+ G P K
Sbjct: 765 STPTTTKE-PTTIHKSPD---------ESTPEL-SAEPTPKALENSPKE----PGVPTTK 809
Query: 1928 LDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHT--------EESMTDDKITEV 1979
P + + T K K E ++L TP T E + T +K TE
Sbjct: 810 ------TPAATKPEMTTTAKDKTTE-----RDLRTTPETTTAAPKMTKETATTTEKTTES 858
Query: 1980 SCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETA 2033
+ T T KI+ K + K T T+ + ETA
Sbjct: 859 KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETA 912
Score = 55.8 bits (133), Expect = 7e-07
Identities = 212/970 (21%), Positives = 302/970 (31%), Gaps = 123/970 (12%)
Query: 1446 ASVTGSKRHPKTKEKAQP---LEDLAGL---KELFQTPVCTDKPTTHEKTTKIACRSQPD 1499
A V +K++ +TK+K P + D AG F+ T H K + +
Sbjct: 105 AEVKDNKKN-RTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAK 163
Query: 1500 PVDTPTSSKPQSKRSLR-KVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTP 1558
P++ S P S S + V +E K T + K T EK A
Sbjct: 164 PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTD----GKEKTTSAKETQS 219
Query: 1559 VQKLDLTENLTGSKRRLQTPKEKAQALED---LAGFKELFQTRGHTEESMTNDKTAKVAC 1615
++K ++L + + L P KA+ L KE T S T +
Sbjct: 220 IEKTS-AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI 278
Query: 1616 KSSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKA 1675
KS+ P K PA + + + K TT PT +
Sbjct: 279 KSAPTTP-KEPAPTTTKSAPTTPK---------------EPAPTTTKEPAPTTPKEPAPT 322
Query: 1676 FMESPKQILDSAASLTGSKRQLRTPKGKSEV-PEDLAGFIELFQTPSHTKESMTNEK--- 1731
+ P +A T + TPK + P++ A TP+ KE K
Sbjct: 323 TTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 382
Query: 1732 -TTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVG 1790
TT + P T +P P A T ++ +P+ K +PA
Sbjct: 383 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT-----KEPSPTTPK-----EPAPT 432
Query: 1791 EEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTD 1850
K T P + T KE A TP PTT
Sbjct: 433 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT------------TPKEPAPTTP 480
Query: 1851 EK---TTKKILCKSPQSDPADTPTNTKQ----RPKRSLKKADVEEEFLAFRKLTPSAGKA 1903
+K TT K + +PA PT TK+ PK E +KLTP+ +
Sbjct: 481 KKPAPTTPKEPAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK 538
Query: 1904 MHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGF---KEL 1960
+ A EK T TP E L + P TP+E A A KE
Sbjct: 539 L----APTTPEKPAPT---TPEE----LAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 587
Query: 1961 FQTPGHTEESMTDDKITEVSCKSPQPDPVK--TPTSSKQRLKISLGKVGVKEEVLPVGKL 2018
T T + + K P K PT+ K+ + K KE K
Sbjct: 588 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK- 646
Query: 2019 TQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAG 2078
+ + T T G + KE A T P T KE A +
Sbjct: 647 -EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA 705
Query: 2079 FKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTST---RRRPKTPLGKRDIVEELS 2135
KEL T STT DK K P + P T + P TP E+S
Sbjct: 706 PKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVS 765
Query: 2136 ALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTG---SKRQPRTPKGKAQPLE 2192
+ T K P + ++ E + L+ + G +K T +
Sbjct: 766 TPTTTKEPTTIHKSPDESTPELSA--EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 823
Query: 2193 DLAGLKELFQTPICT--------DKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLR 2244
D ++L TP T + TT EKTT+ + T T K +
Sbjct: 824 DKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTL 883
Query: 2245 KADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQ 2304
K + K+T + + M+ P+ KD K P P K+
Sbjct: 884 KTTTLAPKVTTTKKTITTTEIMNKPEET-AKPKDRATNSKATTPKPQKPTKAP--KKPTS 940
Query: 2305 TPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPA----STKQRP 2360
T K K P KP T K+ P+ +P A T RP
Sbjct: 941 TKKPKTM--------------PRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRP 986
Query: 2361 KRNLRKADVE 2370
+ VE
Sbjct: 987 NQTPNSKLVE 996
Score = 54.3 bits (129), Expect = 2e-06
Identities = 148/598 (24%), Positives = 203/598 (33%), Gaps = 79/598 (13%)
Query: 994 APKSEKGKITKMPCQSLQPEPINTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETTH 1053
APK K P + EP PT TK+ + KE T S TT
Sbjct: 393 APKKPAPTTPKEPAPTTPKEP--APTTTKEPSPTT-----PKEP----APTTTKSAPTTT 441
Query: 1054 THREPAGDGKSIRTFKE-SPKQILDPA-------ARVTGMKKWPRTPKEEAQSLEDLAGF 1105
P + T KE SP +PA A T K P TPKE A +
Sbjct: 442 KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP----- 496
Query: 1106 KELFQTPGPSEESMTDEKTTKIACKSPPPESVDTP-------TSTKQWPKRSLRKADVEE 1158
+ P P+ T K + P E+ T T K P + A
Sbjct: 497 ----KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP 552
Query: 1159 EFLAL---RKLTPSAGK--AMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQT 1213
E LA + TP+ + A TPK A + A P + A T P T
Sbjct: 553 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA----PTTPKEPAPTTPKEPAPT-T 607
Query: 1214 PKEKAQALEDLAGFKELFQ----TPGHTEELVAAGKTTKIP----CDSPQ-SDPVDTPTS 1264
PKE A L + TP A TTK P CD P + P T +
Sbjct: 608 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPT 667
Query: 1265 TKQRPKRSIRKADVEGELLACRNLMPSAGK--AMHTPKPSVGEEKDIIIFVGTPVQKLDL 1322
T + P + K E + P+ K A TPK +E G D
Sbjct: 668 TPKEPAPTTPK---EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDK 724
Query: 1323 TENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPC-------ES 1375
T + P TPKE A +TP T V+ TTK P ES
Sbjct: 725 PAPTTPKETAPTTPKEPAPTTPKKPA-PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 783
Query: 1376 SPPESAD-TPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAF 1434
+P SA+ TP + PK P K +A K T+ + T++ ++ A
Sbjct: 784 TPELSAEPTPKALENSPKEP--GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAA 841
Query: 1435 RETAKQKLDPAASVTGSK-RHPKTKEKAQPLEDLAGLK-ELFQTPVCTDKPTTHEKT-TK 1491
+ K+ T SK T+ + +D K +T K TT +KT T
Sbjct: 842 PKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITT 901
Query: 1492 IACRSQPD----PVDTPTSSKPQSKRSLRKVDVEEEFFALR--KRTPSAGKAMHTPKP 1543
++P+ P D T+SK + + + ++ + + K P K TP P
Sbjct: 902 TEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTP 959
Score = 38.9 bits (89), Expect = 0.084
Identities = 102/461 (22%), Positives = 150/461 (32%), Gaps = 88/461 (19%)
Query: 994 APKSEKGKITKMPCQSLQPEPI-NTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETT 1052
APK TK P + +P TP T KE K G
Sbjct: 636 APKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK-----GTAP 690
Query: 1053 HTHREPAGDGKSIRTFKESPKQILDPAAR----VTGMKKWPRTPKEEAQSLEDLAGFKEL 1108
T +EPA K +PK++ + T K P TPKE A +
Sbjct: 691 TTLKEPAPTTPK----KPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP-------- 738
Query: 1109 FQTPGPSEESMTDEKTTKIACKSPPPES--VDTPTSTKQWPKRSLRKADVEEEFLALRKL 1166
+ P P+ T +K ++PPP + V TPT+TK+ ++ K+ E
Sbjct: 739 -KEPAPT----TPKKPAPTTPETPPPTTSEVSTPTTTKE--PTTIHKSPDES-------- 783
Query: 1167 TPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAG 1226
TP A TPK K+ G P K A T E +D
Sbjct: 784 TPELS-AEPTPKALENSPKE----PGVPTTKTPAA-----------TKPEMTTTAKDKTT 827
Query: 1227 FKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACR 1286
++L TP E AA K TK +T T+T++ + I + +
Sbjct: 828 ERDLRTTP---ETTTAAPKMTK-----------ETATTTEKTTESKITATTTQVTSTTTQ 873
Query: 1287 NLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDL 1346
+ P + T T K+ T+ + P+E A+ +
Sbjct: 874 DTTPFKITTLKTT---------------TLAPKVTTTKKTITTTEIMNKPEETAKPKDRA 918
Query: 1347 TGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSA 1406
T K P +A +TK P T + R+ T E + A
Sbjct: 919 TNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEA 978
Query: 1407 LKKLTQTSGETTHTDKV---PGGEDKSINAFRETAKQKLDP 1444
+ + T +T ++ V P ED A ET L P
Sbjct: 979 MLQTTTRPNQTPNSKLVEVNPKSEDAG-GAEGETPHMLLRP 1018
>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
sapiens]
Length = 1393
Score = 85.5 bits (210), Expect = 8e-16
Identities = 168/779 (21%), Positives = 292/779 (37%), Gaps = 105/779 (13%)
Query: 2493 EEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRKEK 2552
++P+ ++ + ++T TH E G K +PK ++ S TG R +
Sbjct: 130 KDPMIRNQRSVDPADSTTTHKESAGK----KHITPAPKSKINCRKSTTGKSTVTRKSDKT 185
Query: 2553 ARALEDLVDFKELFSAPGH---TEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPR 2609
R LE + + S H T + + TK S P ++T + +T + T
Sbjct: 186 GRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEE 245
Query: 2610 KEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQ-------RAKKKPNPVEEEPS 2662
E E+ + ++T +E S +E + L + A + P EP+
Sbjct: 246 SEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPT 305
Query: 2663 RRRPRAPKEK-----AQPLED---LAGFTELSETSGHTQE-SLTAGKATKI-PCESPPLE 2712
R R E A+P+E+ A +G T+ +TA + T + P E P E
Sbjct: 306 ENRERTANENTTLSPAEPIENRERTANENTAPFPAGPTENREMTANENTTLFPAE--PTE 363
Query: 2713 VVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTD-ADKEPAGEDKGIKALKESAK 2771
+ TA+ + + + + E + T + E T+ ++ P DK + ES +
Sbjct: 364 HGERTAN-ENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTE 422
Query: 2772 ---QTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTE--ESMTDDKTTKIPCK 2826
+TP + T S P P E+ + + PA G TE E+ ++KTT P +
Sbjct: 423 HGERTPLANENTTPS---PAEPTENRERTANENTTPSPA-GPTENRETTANEKTTLSPVE 478
Query: 2827 SSPELEDTA----TSSKRRPRTRAQKVEVKEELLAVGKLTQTSGE-TTHTDKEPVGEGKG 2881
+ E TA T S P Q+ E K T +S E T H ++ P+
Sbjct: 479 PTENRETTANEKTTPSPAEPTENGQRTPFANE-----KTTSSSAEPTEHGERTPLANENT 533
Query: 2882 TKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLE--DLASFQELSQTPGHTEELANGAA 2939
T + +P + + E + P A+P E D TP E NG
Sbjct: 534 TPSPAEPTENR---ERTANEKTTP----SPAEPTENGDRTPLANEKTTPSLAEPTENGQR 586
Query: 2940 DSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSK-SNTSLPPLPFKR 2998
F + K T S +P + R A + S +P +++ + +N + P P
Sbjct: 587 TPFAN-EKTTSSSAEPTEHEERTPLANE----NTTPSPAEPTENRERTANENTTPSP--A 639
Query: 2999 GGGKDGSVTGTKRLRCMPAPEEIVEELPASKKQRVAP---------------RARGKSSE 3043
G ++ +T ++ PA E A++K +P + S+E
Sbjct: 640 GPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAE 699
Query: 3044 PVVIMKRS-LRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAE 3102
P +R+ L + PAE + + N++ EN+ R+ +N T +
Sbjct: 700 PTEHGERTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRE---RTANENTTPSP 756
Query: 3103 QQITEVFVLAERIEINRNEKKPM---KTSPEMDIQNPDDGARKPIPRDKVTEN-----KR 3154
Q TE ++ P+ KT+P + + ++G R P +K T + +
Sbjct: 757 AQPTE-----------NGDRTPLANEKTTPSL-AEPTENGKRTPFANEKTTSSSAEPTEH 804
Query: 3155 CLRSARQNESSQPKVAEESGGQKSAKVLMQNQKGKGEAGNSDSMCLRSRKTKSQPAAST 3213
R+ NE++ AE + ++ Q N +S + KT PA T
Sbjct: 805 AERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTA--NEKTTPFPAEPT 861
Score = 75.1 bits (183), Expect = 1e-12
Identities = 250/1296 (19%), Positives = 445/1296 (34%), Gaps = 145/1296 (11%)
Query: 1441 KLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDP 1500
+L + + KRH T ++P TDKPT + KT I +S D
Sbjct: 73 ELPKSTEIHEQKRHCNTTRHSKP----------------TDKPTGNSKT--IDHKSSTDN 114
Query: 1501 VDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQ 1560
+ P +S+ S + + + R P+ H +G+K+I P
Sbjct: 115 HEAPPTSEENSSNQGKDPMIRNQ----RSVDPADSTTTHKES---AGKKHITP---APKS 164
Query: 1561 KLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGH-TEESMTNDKTAKVACKSSQ 1619
K++ ++ TG + + + LE + T H T S N ++ KS+
Sbjct: 165 KINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTS 224
Query: 1620 PDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMES 1679
P+K A+SK KT+ G EE S +T + T D K ++
Sbjct: 225 -FPEKITAASKTTYKTT----GTPEE----------SEKTEDSRTTVASD----KLLTKT 265
Query: 1680 PKQILD--SAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTT---- 1733
K I + SA LT S + G++ + E P+ +E NE TT
Sbjct: 266 TKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAE----PTENRERTANENTTLSPA 321
Query: 1734 -KVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAF-RKQTPSAGKAMHTPKPAV-- 1789
+ R + P + P R + + F A + TP PA
Sbjct: 322 EPIENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPT 381
Query: 1790 --GEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNP 1847
GE +P + + P +N + + ++ E T TP P
Sbjct: 382 EHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEP 441
Query: 1848 TTD-EKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHT 1906
T + E+T + SP + T ++ S + E A K TPS +
Sbjct: 442 TENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTEN 501
Query: 1907 PKAAVGEEKDINTFVGTPVEKLDLLGNLP-GSKRRPQTPKEKAKALEDLAGFKELFQTPG 1965
+ + + P E + P ++ +P E + E A K TP
Sbjct: 502 GQRTPFANEKTTSSSAEPTEHGE---RTPLANENTTPSPAEPTENRERTANEK---TTPS 555
Query: 1966 HTEESMTDDKI------TEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEV-LPVGKL 2018
E + D+ T S P + +TP ++++ S +E L
Sbjct: 556 PAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENT 615
Query: 2019 TQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAG 2078
T + + T+ TA + + + + + T E+ P E ++ E A
Sbjct: 616 TPSPAEPTENRERTANENTTPSPAGPTENREM------TANEKTTLFPAEPTENRERTAN 669
Query: 2079 FKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALK 2138
K T E T + + T A + S + T +TPL + +
Sbjct: 670 EK----TTSSPAEPTENGQRTPFANEKTTSSSAE---PTEHGERTPLANENTTLSPAEPT 722
Query: 2139 QLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLK 2198
+ + T +K + TA + P+ + ++ RTP + LA
Sbjct: 723 ENRERTANEKTTPFPAEPTENRERTANENTTPSPA-QPTENGDRTPLANEKTTPSLAEPT 781
Query: 2199 EL-FQTPICTDKPTTHE-KTTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALR 2256
E +TP +K T+ + T+ A R+P + T + +P R E A
Sbjct: 782 ENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENR---------ERTANE 832
Query: 2257 KRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDL 2316
K T + + + ++ F P + + N + P P E + + L
Sbjct: 833 KTTQFPAEPTENRESTANEK--TTPFPAEPTENREWTAN-ENTTLSPAEPTEH-EEMTPL 888
Query: 2317 AGFKELFQTP-----GTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEE 2371
A K G P T+EKTT + + + A+ P R +
Sbjct: 889 ANEKTTLSPAEPTENGERTPFTNEKTTPSSAEPTEHGERTPLANEITTPSR--AEPTEHG 946
Query: 2372 EFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKA 2431
E +A K TPS K + + V+++ ++ T + L N + P E
Sbjct: 947 ERIANEKATPSPAKPTEHGETTVNEDTTPSSAEPTENGERTPLAN-ENTTTSPTESTEHG 1005
Query: 2432 EALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDM 2491
E + + H E + + ++ T S P T +++ P+ +
Sbjct: 1006 ERTANEKTTPSPAEPTEHGERTPSANEKTIPSPAKPTEHEEMTPSANENTTPSPVKPTEH 1065
Query: 2492 KEE-PLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESP----KQILDPAASVTGSRRQL 2546
E+ LA K+T + T+ + T ++ I P ++ P +T S +
Sbjct: 1066 GEKTTLANEKITLSPEGPTEHGAKTTSANEKITPSLAKPTEHGERTTSPNDKITSSAAES 1125
Query: 2547 RTRKEKARALEDLVDFKELFSAPGH-----TEESMTIDKNTKIPCKSP--PPELTDTATS 2599
+++A + + AP ++ +K T++ KS P + T T
Sbjct: 1126 TEHRDRATSANVIT------PAPAEPIKHAKRTTLAHEKMTQVTEKSTEHPEKTTSTTEK 1179
Query: 2600 TKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEE 2659
T R P+ K L + E+ T G++T ++P + + K PV+
Sbjct: 1180 TTRTPE-------KPTLYS-EKTICTKGKNTPVPEKPTENLGNTTLTTETIKA---PVKS 1228
Query: 2660 EPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQES 2695
+ + A + +P + G L+ TS H ++
Sbjct: 1229 TENPEKTAAVTKTIKPSVKVTGDKSLTTTSSHLNKT 1264
Score = 68.9 bits (167), Expect = 8e-11
Identities = 200/927 (21%), Positives = 304/927 (32%), Gaps = 136/927 (14%)
Query: 1324 ENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADT 1383
EN T S P E D T T +A TT P E +
Sbjct: 390 ENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTA 449
Query: 1384 PTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLD 1443
+T P P E R E +A +K T + E T + E + + T +
Sbjct: 450 NENTTPSPAGPTENR----ETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRT 505
Query: 1444 PAAS--VTGSKRHP-------------KTKEKAQPLEDLAGLKELFQTPVCTD------- 1481
P A+ T S P T A+P E+ TP +
Sbjct: 506 PFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDR 565
Query: 1482 KPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTP 1541
P +EKTT + TP +++ + S + EE RTP A + TP
Sbjct: 566 TPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEE-------RTPLANENT-TP 617
Query: 1542 KPAVSGE-KNIYAFMGTPVQKLDLTEN--LTGSKRRLQTPKEKAQALEDLAGFKELFQTR 1598
PA E + A T TEN +T +++ P E + E A K
Sbjct: 618 SPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPA 677
Query: 1599 GHTEES----MTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKE--ELLAVGKL 1652
TE N+KT + + ++ ++ P +++ T+L E E A K
Sbjct: 678 EPTENGQRTPFANEKTTSSSAEPTE-HGERTPLANE---NTTLSPAEPTENRERTANEKT 733
Query: 1653 TQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGKSEVPEDLAG 1712
T E T + + SP Q ++ RTP + LA
Sbjct: 734 TPFPAEPTENRERTANENTT-----PSPAQPTENGD---------RTPLANEKTTPSLAE 779
Query: 1713 FIELFQTPSHTKESMTNEKTTKVS----YRASQPDLVDTPTSSKPQPKRSLRKADTEEEF 1768
T + + NEKTT S A + L + T+S P R+ E+
Sbjct: 780 -----PTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKT 834
Query: 1769 LAF----RKQTPSAGKAMHTPKPAVGEEK-----DINTFLGTPVQKLDQPGNLPGSNRRL 1819
F + S TP PA E + NT L +P + + P +N +
Sbjct: 835 TQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTL-SPAEPTEHEEMTPLANEKT 893
Query: 1820 QTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKR 1879
+ E T F TP + PT + T P ++ TP+ +
Sbjct: 894 TLSPAEPTENGERTPFTNEKTTPSSAEPTEHGERT-------PLANEITTPSRAEPTE-- 944
Query: 1880 SLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKR 1939
E +A K TPS K + V E+ ++ T + L N +
Sbjct: 945 -------HGERIANEKATPSPAKPTEHGETTVNEDTTPSSAEPTENGERTPLAN----EN 993
Query: 1940 RPQTPKEKAKALEDLAGFKEL----------FQTPGHTEESMTD-------DKITEVSCK 1982
+P E + E A K +TP E+++ +++T + +
Sbjct: 994 TTTSPTESTEHGERTANEKTTPSPAEPTEHGERTPSANEKTIPSPAKPTEHEEMTPSANE 1053
Query: 1983 SPQPDPVKTPTSSKQRL-----KISLGKVGVKEEVLPV----GKLTQTSGKTTQTHRETA 2033
+ P PVK PT ++ KI+L G E K+T + K T+ T
Sbjct: 1054 NTTPSPVK-PTEHGEKTTLANEKITLSPEGPTEHGAKTTSANEKITPSLAKPTEHGERTT 1112
Query: 2034 GDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEEST 2093
I + + + D A + P P + A+ LA K T TE
Sbjct: 1113 SPNDKITSSAAESTEHRDRATSANVITPAPAEPIKHAKR-TTLAHEKMTQVTEKSTEHPE 1171
Query: 2094 TDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEE--LSALKQLTQTTHTDKVPG 2151
TT+ ++P + PT + GK V E L T TT T K P
Sbjct: 1172 KTTSTTEKTTRTP-----EKPTLYSEKTICTKGKNTPVPEKPTENLGNTTLTTETIKAPV 1226
Query: 2152 DEDKGINVFRETAKQKLDPAASVTGSK 2178
+ K + P+ VTG K
Sbjct: 1227 KSTENPEKTAAVTK-TIKPSVKVTGDK 1252
Score = 60.1 bits (144), Expect = 4e-08
Identities = 189/953 (19%), Positives = 308/953 (32%), Gaps = 183/953 (19%)
Query: 2086 PDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPK----TPLGKRD-IVEELSALKQL 2140
P E+T ++KTT + P E+ +T + + P T G+R E +
Sbjct: 460 PTENRETTANEKTTLSPVE--PTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSA 517
Query: 2141 TQTTHTDKVP-GDEDKGINVFRETAKQKLDPAASVTGSKRQP-----RTPKGKAQPLEDL 2194
T H ++ P +E+ + T ++ T S +P RTP + L
Sbjct: 518 EPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSL 577
Query: 2195 AGLKELFQ-TPICTDK-------PTTHEKTTKIACRSPQPDPVG-------------TPT 2233
A E Q TP +K PT HE+ T +A + P P TP+
Sbjct: 578 AEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPS 637
Query: 2234 IFKPQSKRSLRKADV----------EEESLALRKRTPSVGKAMD----TP---------- 2269
P R + + E A K T S + + TP
Sbjct: 638 PAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSS 697
Query: 2270 -KPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGT 2328
+P E+ A T + + N + TP A+ E+ TP
Sbjct: 698 AEPTEHGERTPLANENTTLSPAEPTENRERTANEKTTPFP-AEPTENRERTANENTTPSP 756
Query: 2329 DKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMD 2388
+PT + T +A + P + + K+ P N + E +RTP A +
Sbjct: 757 AQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANE-NT 815
Query: 2389 TPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKEL-FQTP 2447
T PA E T +++ Q P E E E K F
Sbjct: 816 TSSPAEPTENRERT----------------ANEKTTQFPAEPTENRESTANEKTTPFPAE 859
Query: 2448 GHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEE-PLAVSKLTRTSG 2506
T ++ T +S P T ++++ P + E P K T +S
Sbjct: 860 PTENREWTANENTTLSPAEPTEHEEMTPLANEKTTLSPAEPTENGERTPFTNEKTTPSSA 919
Query: 2507 ETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELF 2566
E T+ H E T + I T SR +
Sbjct: 920 EPTE-HGERTPLANEI----------------TTPSRAE--------------------- 941
Query: 2567 SAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTS 2626
P E + +K T P K P E +T + P + E E T TS
Sbjct: 942 --PTEHGERIANEKATPSPAK--PTEHGETTVNEDTTPSSAEPTENGERTPLANENTTTS 997
Query: 2627 GQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELS 2686
+ H E + A +K P EP+ R P + + A TE
Sbjct: 998 PTESTEHGE------------RTANEKTTPSPAEPTEHGERTPSANEKTIPSPAKPTEHE 1045
Query: 2687 ETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTS 2746
E + E+ T P P E + T +K+ + E T+
Sbjct: 1046 EMTPSANENTT-------PSPVKPTEHGEKTTLAN-------EKITLSPEGP----TEHG 1087
Query: 2747 GETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDP 2806
+TT A+++ + E ++T +P +T S R+ A + +
Sbjct: 1088 AKTTSANEKIT---PSLAKPTEHGERTTSPNDKITSSAAESTEHRDRATSANVITPAPAE 1144
Query: 2807 AAGHTEE-SMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTS 2865
H + ++ +K T++ KS+ E T +++++ RT + E+ + T
Sbjct: 1145 PIKHAKRTTLAHEKMTQVTEKSTEHPEKTTSTTEKTTRTPEKPTLYSEKTIC------TK 1198
Query: 2866 GETTHTDKEPVGEGKG-----TKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLAS 2920
G+ T ++P E G T+ K P K + E + A + +P +
Sbjct: 1199 GKNTPVPEKPT-ENLGNTTLTTETIKAPVKSTENPE-------KTAAVTKTIKPSVKVTG 1250
Query: 2921 FQELSQTPGHTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGD 2973
+ L+ T H + T Q P L SR L + E G+
Sbjct: 1251 DKSLTTTSSHLNK---------TEVTHQVPTGSFTLITSRTKLSSITSEATGN 1294
Score = 58.2 bits (139), Expect = 1e-07
Identities = 205/1072 (19%), Positives = 345/1072 (32%), Gaps = 146/1072 (13%)
Query: 1111 TPGPSEESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLALRKLTPSA 1170
TP P+E + E+T P E ++ T E R++T +
Sbjct: 298 TPSPAEPTENRERTANENTTLSPAEPIENRERTANENTAPFPAGPTEN-----REMTANE 352
Query: 1171 GKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGFKEL 1230
+ +P E+ + G ++ +P E + E +
Sbjct: 353 NTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFAND- 411
Query: 1231 FQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMP 1290
+T + E G+ T + ++ P + PT ++R A N P
Sbjct: 412 -KTTSSSAESTEHGERTPLANENTTPSPAE-PTENRERT--------------ANENTTP 455
Query: 1291 SAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDLTGFK 1350
S + + E+ + T ++ E T S P + + T
Sbjct: 456 SPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSS 515
Query: 1351 ELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSALKKL 1410
T +A TT P E + T P P E D + L+ K
Sbjct: 516 SAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGD-RTPLANEKTT 574
Query: 1411 TQTSGETTHTDKVPGGEDKSINAFRE-TAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAG 1469
+ T + + P +K+ ++ E T ++ P A+ T A+P E+
Sbjct: 575 PSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLAN------ENTTPSPAEPTENRER 628
Query: 1470 LKELFQT-----PVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEF 1524
T P + T +EKTT + T + K S + + +
Sbjct: 629 TANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERT-ANEKTTSSPAEPTENGQRTP 687
Query: 1525 FALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQA 1584
FA K T S+ +P GE+ A T + + TEN R +T EK
Sbjct: 688 FANEKTTSSSA------EPTEHGERTPLANENTTLSPAEPTEN------RERTANEKT-- 733
Query: 1585 LEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKE 1644
T E + ++TA S P +N
Sbjct: 734 ------------TPFPAEPTENRERTANENTTPSPAQPTEN------------------- 762
Query: 1645 ELLAVGKLTQTSGE-TTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGK 1703
G T + E TT + EPT +GK E +++S ++ RTP
Sbjct: 763 -----GDRTPLANEKTTPSLAEPTENGKRTPFANEK-----TTSSSAEPTEHAERTPLAN 812
Query: 1704 SEVPEDLAGFIELFQTPSHTKESMTNEKTTK-----VSYRASQPDLVDTPTSSKPQPKRS 1758
A P+ +E NEKTT+ R S + TP ++P R
Sbjct: 813 ENTTSSPA-------EPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTENRE 865
Query: 1759 LRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRR 1818
T E P+ + M P E+ + +P + + P +N +
Sbjct: 866 W----TANENTTLSPAEPTEHEEM---TPLANEKTTL-----SPAEPTENGERTPFTNEK 913
Query: 1819 LQTRKEKAQALEELTGFRELFQTPCTDNPTT-DEKTTKKILCKSP--QSDPADTPTNTKQ 1875
+ E T TP PT E+ + SP ++ +T N
Sbjct: 914 TTPSSAEPTEHGERTPLANEITTPSRAEPTEHGERIANEKATPSPAKPTEHGETTVNEDT 973
Query: 1876 RPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLGNLP 1935
P + + E LA T S T GE +P E + P
Sbjct: 974 TPSSAEPTENGERTPLANENTTTSP-----TESTEHGERTANEKTTPSPAEPTEHGERTP 1028
Query: 1936 GSKRRPQTPKEKAKALEDLAGFKELFQTPG------HTEE-SMTDDKITEVSCKSPQPDP 1988
+ + K E++ TP H E+ ++ ++KIT +S + P
Sbjct: 1029 SANEKTIPSPAKPTEHEEMTPSANENTTPSPVKPTEHGEKTTLANEKIT-LSPEGPTEHG 1087
Query: 1989 VKTPTSSKQRLKISLGKVGVKEE--VLPVGKLTQTSGKTTQTHRETAGDGKSI-----KA 2041
KT TS+ +++ SL K E P K+T ++ ++T+ HR+ A I +
Sbjct: 1088 AKT-TSANEKITPSLAKPTEHGERTTSPNDKITSSAAESTE-HRDRATSANVITPAPAEP 1145
Query: 2042 FKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKI 2101
K + + L E+ P++ + E E P E T K
Sbjct: 1146 IKHAKRTTLAHEKMTQVTEKSTEHPEKTTSTTEKTTRTPE---KPTLYSEKTICTKGKNT 1202
Query: 2102 ACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDE 2153
P E++ T T K P+ + E+ +A+ + + + KV GD+
Sbjct: 1203 PVPEKPTENLGNTTLTTETIKAPVKSTENPEKTAAVTKTIKP--SVKVTGDK 1252
Score = 57.4 bits (137), Expect = 2e-07
Identities = 215/1005 (21%), Positives = 343/1005 (34%), Gaps = 152/1005 (15%)
Query: 1051 TTHTHREPAGDGKSIRTFKESPKQILDPAARVTGMKKWPRTPKEEAQSLEDLAGFKELFQ 1110
T H R P + K+ + ES + + P +P E ++ E A
Sbjct: 400 TEHGERTPFANDKTTSSSAESTEH--GERTPLANENTTP-SPAEPTENRERTANENTTPS 456
Query: 1111 TPGPSE--ESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLALRKLTP 1168
GP+E E+ +EKTT + P E+ +T + K P + + + A K T
Sbjct: 457 PAGPTENRETTANEKTTLSPVE--PTENRETTANEKTTPSPAEPTENGQRTPFANEKTTS 514
Query: 1169 SAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGFK 1228
S+ +P E+ TP+ ++ +P E
Sbjct: 515 SSA------EPTEHGER-------TPL----------ANENTTPSPAE------------ 539
Query: 1229 ELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNL 1288
P E A KTT P + ++ D ++ S+ + G+ N
Sbjct: 540 -----PTENRERTANEKTTPSPAEPTENG--DRTPLANEKTTPSLAEPTENGQRTPFANE 592
Query: 1289 MPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDLTG 1348
++ A +P+ EE+ TP+ EN T S P T E A E+ T
Sbjct: 593 KTTSSSA----EPTEHEER-------TPL----ANENTTPSPAEP-TENRERTANENTTP 636
Query: 1349 FKELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSALK 1408
P E A KTT P E + T P P E + Q+ A +
Sbjct: 637 SP---AGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTE--NGQRTPFANE 691
Query: 1409 KLTQTSGE-TTHTDKVPGGEDKSINAFRE-------TAKQKLDPAASVTGSKRHPKTKEK 1460
K T +S E T H ++ P + + + E TA +K P + R E
Sbjct: 692 KTTSSSAEPTEHGERTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRERTANEN 751
Query: 1461 AQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDV 1520
P T P +EKTT + TP +++ + S +
Sbjct: 752 TTP-------SPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEH 804
Query: 1521 EEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKE 1580
E + T S+ + + EK F P + + T N ++ P E
Sbjct: 805 AERTPLANENTTSSPAEPTENRERTANEKTT-QFPAEPTENRESTAN----EKTTPFPAE 859
Query: 1581 KAQALEDLAGFKELFQTRGHTE-ESMTNDKTAKVACKSSQP--DPDKNPASSKRRLKTSL 1637
+ E A TE E MT K ++P + ++ P ++++ +S
Sbjct: 860 PTENREWTANENTTLSPAEPTEHEEMTPLANEKTTLSPAEPTENGERTPFTNEKTTPSS- 918
Query: 1638 GKVGVKEELLAVGKLTQTSGE-TTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQ 1696
E G+ T + E TT + EPT G ++I + A+ + +K
Sbjct: 919 ------AEPTEHGERTPLANEITTPSRAEPTEHG----------ERIANEKATPSPAK-- 960
Query: 1697 LRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQPDLVDTPTSSKPQPK 1756
T G++ V ED TPS + + E+T + + +PT S +
Sbjct: 961 -PTEHGETTVNED--------TTPSSAEPTENGERTP-----LANENTTTSPTESTEHGE 1006
Query: 1757 RSLRKADTEE--EFLAFRKQTPSAG-KAMHTP-KPAVGEEKDINTFLGT---PVQKLDQP 1809
R+ + T E ++TPSA K + +P KP EE + T PV+ +
Sbjct: 1007 RTANEKTTPSPAEPTEHGERTPSANEKTIPSPAKPTEHEEMTPSANENTTPSPVKPTEHG 1066
Query: 1810 GNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTT-DEKTTK---KILCKSPQS- 1864
+N ++ E T TP PT E+TT KI + +S
Sbjct: 1067 EKTTLANEKITLSPEGPTEHGAKTTSANEKITPSLAKPTEHGERTTSPNDKITSSAAEST 1126
Query: 1865 ---DPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAM-HTPKAAVGEEKDINTF 1920
D A + P +K A + LA K+T K+ H K EK T
Sbjct: 1127 EHRDRATSANVITPAPAEPIKHA--KRTTLAHEKMTQVTEKSTEHPEKTTSTTEKTTRT- 1183
Query: 1921 VGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVS 1980
EK L + TP + K E+L +T +S + + T
Sbjct: 1184 ----PEKPTLYSEKTICTKGKNTPVPE-KPTENLGNTTLTTETIKAPVKSTENPEKTAAV 1238
Query: 1981 CKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKT 2025
K+ +P T S L K V +V P G T + +T
Sbjct: 1239 TKTIKPSVKVTGDKSLTTTSSHLNKTEVTHQV-PTGSFTLITSRT 1282
Score = 45.1 bits (105), Expect = 0.001
Identities = 182/889 (20%), Positives = 298/889 (33%), Gaps = 104/889 (11%)
Query: 838 NGNVAKTPRNTYKMTSLETKTSDTETEPSKTVSTANRSGRSTEFRNIQKL-PVESKSEET 896
N N +P T +T++ T PS T NR + E + + P E++
Sbjct: 431 NENTTPSPAEP---TENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTA 487
Query: 897 NTEIVEC---ILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDEKMKA---MKR 950
N + + GQ+ ++ E P E + EN A R
Sbjct: 488 NEKTTPSPAEPTENGQRTPFANEKTTSSSAE---PTEHGERTPLANENTTPSPAEPTENR 544
Query: 951 SRTWGQKCAPM-------SDLTDLKSLPDT-ELMKDTARGQN---LLQTQDHAKAPKSEK 999
RT +K P D T L + T L + T GQ + + A +E
Sbjct: 545 ERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEH 604
Query: 1000 GKITKMPCQSLQPEPINTPTHTKQQL---KASLGKVGVKE--ELLAVGKFTRTSGETTHT 1054
+ T + ++ P P PT +++ + G E E+ A K T E T
Sbjct: 605 EERTPLANENTTPSPAE-PTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEPTEN 663
Query: 1055 HREPAGDGKSIRTFKESPKQILDPAARVTGMKKWPRTPKEEAQSLE-----DLAGFKELF 1109
A + + SP + + R + +T A+ E LA
Sbjct: 664 RERTANEKTT-----SSPAEPTENGQRTPFANE--KTTSSSAEPTEHGERTPLANENTTL 716
Query: 1110 QTPGPSE--ESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLALRKLT 1167
P+E E +EKTT + P E+ + + P + + + LA K T
Sbjct: 717 SPAEPTENRERTANEKTTPFPAE--PTENRERTANENTTPSPAQPTENGDRTPLANEKTT 774
Query: 1168 PSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGF 1227
PS + K + + P + + T ++ +P E + E A
Sbjct: 775 PSLAEPTENGKRTPFANEKTTSSSAEPTEHAE--RTPLANENTTSSPAEPTENRERTANE 832
Query: 1228 K--ELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLAC 1285
K + P E A KTT P + ++ +T P ++
Sbjct: 833 KTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLANEK 892
Query: 1286 RNLMPSAGKAMHTPKPSVGEEKDIIIFVGTP-VQKLDLTENLTGSKRRPQTPKEEAQALE 1344
L P+ P E+ T ++ L +T R T E A E
Sbjct: 893 TTLSPAEPTENGERTPFTNEKTTPSSAEPTEHGERTPLANEITTPSRAEPTEHGERIANE 952
Query: 1345 DLTGFKELFQTPGH-TEEAVAAGKTTKMPCESSPPESAD-TPTSTRRQPKTPLEKRDVQK 1402
T +P TE P + P E+ + TP + +P E +
Sbjct: 953 KAT------PSPAKPTEHGETTVNEDTTPSSAEPTENGERTPLANENTTTSPTESTE-HG 1005
Query: 1403 ELSALKKLTQTSGE-TTHTDKVPGGEDKSI-NAFRETAKQKLDPAASVTGSKRHPKTKEK 1460
E +A +K T + E T H ++ P +K+I + + T +++ P+A+ + K E
Sbjct: 1006 ERTANEKTTPSPAEPTEHGERTPSANEKTIPSPAKPTEHEEMTPSANENTTPSPVKPTEH 1065
Query: 1461 AQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPT-----SSKPQSKRSL 1515
+ LA K + + PT H T A + PT ++ P K +
Sbjct: 1066 GEK-TTLANEK----ITLSPEGPTEHGAKTTSANEKITPSLAKPTEHGERTTSPNDKITS 1120
Query: 1516 RKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRL 1575
+ E R R SA P + K Q +TE T +
Sbjct: 1121 SAAESTEH----RDRATSANVITPAPAEPIKHAKRTTLAHEKMTQ---VTEKSTEHPEKT 1173
Query: 1576 QTPKEKAQALEDLAGF--KELFQTRGHT-------EESMTN----DKTAKVACKSSQPDP 1622
+ EK + ++ T+G E++ N +T K KS++ +P
Sbjct: 1174 TSTTEKTTRTPEKPTLYSEKTICTKGKNTPVPEKPTENLGNTTLTTETIKAPVKSTE-NP 1232
Query: 1623 DKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTS---GETTHTHTEPTG 1668
+K A +K +K S+ G K LT TS +T TH PTG
Sbjct: 1233 EKTAAVTK-TIKPSVKVTGDK-------SLTTTSSHLNKTEVTHQVPTG 1273
>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical
region 1 [Homo sapiens]
Length = 1400
Score = 83.2 bits (204), Expect = 4e-15
Identities = 178/812 (21%), Positives = 295/812 (36%), Gaps = 109/812 (13%)
Query: 2493 EEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRKEK 2552
++P+ ++ + ++T TH E G K +PK ++ S TG R +
Sbjct: 192 KDPMIRNQRSVDPADSTTTHKESAGK----KHITPAPKSKINCRKSTTGKSTVTRKSDKT 247
Query: 2553 ARALEDLVDFKELFSAPGH--------TEESMTIDKNTKIPCK--------------SPP 2590
R LE + + S H + S T K+T P K
Sbjct: 248 GRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEE 307
Query: 2591 PELTDTATSTKRCPK--TRPRKEVKEELSAVERLTQT------SGQSTHTHKEPASGDEG 2642
E T+ + +T K T+ K ++E +SA E LTQ+ G T S E
Sbjct: 308 SEKTEDSRTTVASDKLLTKTTKNIQETISANE-LTQSLAEPTEHGGRTANENNTPSPAEP 366
Query: 2643 IKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKAT 2702
+ ++ A + EP+ R R E P AG TE E + + +L
Sbjct: 367 TENRERTANENTTLSPAEPTENRERTANENTAPFP--AGPTENREMTANENTTL------ 418
Query: 2703 KIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTD-ADKEPAGEDK 2761
P E P E + TA+ + + + + E + T + E T+ ++ P DK
Sbjct: 419 -FPAE--PTEHGERTAN-ENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDK 474
Query: 2762 GIKALKESAK---QTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTE--ESMT 2816
+ ES + +TP + T S P P E+ + + PA G TE E+
Sbjct: 475 TTSSSAESTEHGERTPLANENTTPS---PAEPTENRERTANENTTPSPA-GPTENRETTA 530
Query: 2817 DDKTTKIPCKSSPELEDTA----TSSKRRPRTRAQKVEVKEELLAVGKLTQTSGE-TTHT 2871
++KTT P + + E TA T S P Q+ E K T +S E T H
Sbjct: 531 NEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANE-----KTTSSSAEPTEHG 585
Query: 2872 DKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLE--DLASFQELSQTPG 2929
++ P+ T + +P + + E + P A+P E D TP
Sbjct: 586 ERTPLANENTTPSPAEPTENR---ERTANEKTTP----SPAEPTENGDRTPLANEKTTPS 638
Query: 2930 HTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSK-SN 2988
E NG F + K T S +P + R A + S +P +++ + +N
Sbjct: 639 LAEPTENGQRTPFAN-EKTTSSSAEPTEHEERTPLANE----NTTPSPAEPTENRERTAN 693
Query: 2989 TSLPPLPFKRGGGKDGSVTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIM 3048
+ P P G ++ +T ++ PA E A++K +P +EP
Sbjct: 694 ENTTPSP--AGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSP------AEPT--- 742
Query: 3049 KRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEV 3108
+ +R A E ++ E + EN +S +N+ + T
Sbjct: 743 -----ENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAGPTENRERTANEKTTP 797
Query: 3109 FVLAERIEINRNEKKPMKTSPEMDIQNPDDGARKPIPRDKVTEN-----KRCLRSARQNE 3163
F AE E NR T+P Q ++G R P+ +K T + + R+ NE
Sbjct: 798 FP-AEPTE-NRERTANENTTPS-PAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANE 854
Query: 3164 SSQPKVAEESGGQKSAKVLMQNQKGKGEAGNSDSMCLRSRKTKSQPAAST--LESKSVQR 3221
+ AE + + + +N + + KT PA T ES + ++
Sbjct: 855 KTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANEK 914
Query: 3222 VTRSVKRCAENPK-KAEDNVCVKKIRTRSHRD 3252
T EN + A +N + H +
Sbjct: 915 TTPFPAEPTENREWTANENTTLSPAEPTEHEE 946
Score = 58.9 bits (141), Expect = 8e-08
Identities = 174/856 (20%), Positives = 296/856 (34%), Gaps = 109/856 (12%)
Query: 1441 KLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDP 1500
+L + + KRH T ++P TDKPT + KT I +S D
Sbjct: 135 ELPKSTEIHEQKRHCNTTRHSKP----------------TDKPTGNSKT--IDHKSSTDN 176
Query: 1501 VDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQ 1560
+ P +S+ S + + + R P+ H +G+K+I P
Sbjct: 177 HEAPPTSEENSSNQGKDPMIRNQ----RSVDPADSTTTHKES---AGKKHITP---APKS 226
Query: 1561 KLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGH-TEESMTNDKTAKVACKSSQ 1619
K++ ++ TG + + + LE + T H T S N ++ KS+
Sbjct: 227 KINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTS 286
Query: 1620 PDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMES 1679
P+K A+SK KT+ G EE S +T + T D K ++
Sbjct: 287 -FPEKITAASKTTYKTT----GTPEE----------SEKTEDSRTTVASD----KLLTKT 327
Query: 1680 PKQILD--SAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTT--KV 1735
K I + SA LT S + G++ + E P+ +E NE TT
Sbjct: 328 TKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAE----PTENRERTANENTTLSPA 383
Query: 1736 SYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAM----HTPKPAV-- 1789
++ + T+ P R+ E F + G+ TP PA
Sbjct: 384 EPTENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPT 443
Query: 1790 --GEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNP 1847
GE +P + + P +N + + ++ E T TP P
Sbjct: 444 EHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEP 503
Query: 1848 TTD-EKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHT 1906
T + E+T + SP + T ++ S + E A K TPS +
Sbjct: 504 TENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTEN 563
Query: 1907 PKAAVGEEKDINTFVGTPVEKLDLLGNLP-GSKRRPQTPKEKAKALEDLAGFKELFQTPG 1965
+ + + P E + P ++ +P E + E A K TP
Sbjct: 564 GQRTPFANEKTTSSSAEPTEHGE---RTPLANENTTPSPAEPTENRERTANEK---TTPS 617
Query: 1966 HTEESMTDDKI------TEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEV-LPVGKL 2018
E + D+ T S P + +TP ++++ S +E L
Sbjct: 618 PAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENT 677
Query: 2019 TQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAG 2078
T + + T+ TA + + + + + T E+ P E ++ E A
Sbjct: 678 TPSPAEPTENRERTANENTTPSPAGPTENREM------TANEKTTLFPAEPTENRERTAN 731
Query: 2079 FKELFQTPDHTEEST----TDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEEL 2134
K + TE ++KTT + + P TP + +P G + E
Sbjct: 732 EKTTSSPAEPTENGQRTPFANEKTTSSSAE-PTEHGERTPLANENTTLSPAGPTENRERT 790
Query: 2135 SALKQL---TQTTHTDKVPGDEDKGINVFRETAKQKLDPAAS--VTGSKRQPRTPKGKAQ 2189
+ K + T + +E+ + + T P A+ T S +P T GK
Sbjct: 791 ANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEP-TENGKRT 849
Query: 2190 PLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQS---KRSLRKA 2246
P + +T + +PT H + T +A + P PT + ++ K + A
Sbjct: 850 PFAN-------EKTTSSSAEPTEHAERTPLANENTTSSP-AEPTENRERTANEKTTQFPA 901
Query: 2247 DVEE--ESLALRKRTP 2260
+ E ES A K TP
Sbjct: 902 EPTENRESTANEKTTP 917
Score = 51.6 bits (122), Expect = 1e-05
Identities = 113/540 (20%), Positives = 175/540 (32%), Gaps = 84/540 (15%)
Query: 1324 ENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADT 1383
EN T S P E D T T +A TT P E +
Sbjct: 452 ENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTA 511
Query: 1384 PTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLD 1443
+T P P E R+ T+ E T V E++ A +T
Sbjct: 512 NENTTPSPAGPTENRET------------TANEKTTLSPVEPTENRETTANEKTTP---S 556
Query: 1444 PAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDT 1503
PA +R P EK T + +PT H + T +A + T
Sbjct: 557 PAEPTENGQRTPFANEK---------------TTSSSAEPTEHGERTPLANEN-----TT 596
Query: 1504 PTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLD 1563
P+ ++P R E A K TPS +P +G++ A T +
Sbjct: 597 PSPAEPTENR---------ERTANEKTTPSPA------EPTENGDRTPLANEKTTPSLAE 641
Query: 1564 LTENLTGSKRRLQTPKEKAQAL-----EDLAGFKELFQTRGHTEESMTNDKTAKVACKSS 1618
TEN G + K + + E+ T E + ++TA S
Sbjct: 642 PTEN--GQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPS 699
Query: 1619 QPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFME 1678
P +N + KT+L E + + +TT + EPT +G+ E
Sbjct: 700 PAGPTENREMTANE-KTTLFPAEPTE-----NRERTANEKTTSSPAEPTENGQRTPFANE 753
Query: 1679 SPKQILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYR 1738
+++S ++ RTP AG P+ +E NEKTT
Sbjct: 754 K-----TTSSSAEPTEHGERTPLANENTTLSPAG-------PTENRERTANEKTTPFPAE 801
Query: 1739 ASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTF 1798
++ ++ P P + D LA K TPS + K + +
Sbjct: 802 PTENRERTANENTTPSPAQPTENGDRTP--LANEKTTPSLAEPTENGKRTPFANEKTTSS 859
Query: 1799 LGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPC--TDN--PTTDEKTT 1854
P + ++ P +N + + E T + Q P T+N T +EKTT
Sbjct: 860 SAEPTEHAER---TPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANEKTT 916
Score = 45.8 bits (107), Expect = 7e-04
Identities = 240/1289 (18%), Positives = 419/1289 (32%), Gaps = 182/1289 (14%)
Query: 1601 TEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETT 1660
T++ N KT + KSS + + P S + ++ GK + + + + ++T
Sbjct: 158 TDKPTGNSKT--IDHKSSTDNHEAPPTSEEN--SSNQGK-----DPMIRNQRSVDPADST 208
Query: 1661 HTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTP 1720
TH E G K +PK ++ S TG R E ++ T
Sbjct: 209 TTHKESAGK----KHITPAPKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTSTS 264
Query: 1721 SH--------TKESMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFR 1772
SH + S T +K+T + + T+ P+ E E
Sbjct: 265 SHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPE----------ESEKTEDS 314
Query: 1773 KQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEEL 1832
+ T ++ K + + E N + + + G N
Sbjct: 315 RTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENN--------------- 359
Query: 1833 TGFRELFQTPCTDNPTTD-EKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFL 1891
TP PT + E+T + SP ++P + T E
Sbjct: 360 --------TPSPAEPTENRERTANENTTLSP-AEPTENRERTANENTAPFPAGPTEN--- 407
Query: 1892 AFRKLTPSAGKAMHTPKAAVGEEKDIN-TFVGTPVEKLDLLGNLPGSKRRPQTPKEKAKA 1950
R++T + + + E+ N +P E + G ++ +P E +
Sbjct: 408 --REMTANENTTLFPAEPTEHGERTANENTTPSPAEPTEH-GERTANENTTPSPAEPTEH 464
Query: 1951 LEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRL---KISLGKVG 2007
E + +T + ES + T ++ ++ P P + PT +++R + G
Sbjct: 465 GERTPFAND--KTTSSSAESTEHGERTPLANENTTPSPAE-PTENRERTANENTTPSPAG 521
Query: 2008 VKEE----------VLPV----GKLTQTSGKTTQTHRETAGDGKSIK-AFKESAKQMLDP 2052
E + PV + T + KTT + E +G+ A +++ +P
Sbjct: 522 PTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEP 581
Query: 2053 ANYGT----GMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPP 2108
+G E +P E ++ E A K TP E + D+T K+ P
Sbjct: 582 TEHGERTPLANENTTPSPAEPTENRERTANEKT---TPSPAEPTENGDRTPLANEKTTP- 637
Query: 2109 ESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKL 2168
S+ PT +R TP E + T H ++ P + T
Sbjct: 638 -SLAEPTENGQR--TPFAN-----EKTTSSSAEPTEHEERTPLANEN-------TTPSPA 682
Query: 2169 DPAASV--TGSKRQPRTPKGKAQPLEDLAGLKE-LFQT-PICTDKPTTHEKTTKIACRSP 2224
+P + T ++ +P G + E A K LF P + T +EKTT SP
Sbjct: 683 EPTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTS----SP 738
Query: 2225 -QPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFM 2283
+P G T F + S E +RTP + T PAG E +
Sbjct: 739 AEPTENGQRTPFANEKTTSSSAEPTEHG-----ERTP-LANENTTLSPAGPTENRERT-- 790
Query: 2284 GTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACK 2343
+++ P E + E A TP +PT + T +A +
Sbjct: 791 --------------ANEKTTPFPAEPTENRERTANENT---TPSPAQPTENGDRTPLANE 833
Query: 2344 SPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTF 2403
P + + K+ P N + E +RTP A + T PA E T
Sbjct: 834 KTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANE-NTTSSPAEPTENRERT- 891
Query: 2404 VETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKEL-FQTPGHTEESMTDDKITEV 2462
+++ Q P E E E K F T ++ T +
Sbjct: 892 ---------------ANEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTL 936
Query: 2463 SCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAV-SKLTRTSGETTQTHTE-PTGDSK 2520
S P T + L+ P + E P + + + T+G + T +E T +
Sbjct: 937 SPAEPTEHEEMTPLMVDENLQAPFRQGSCAERPKDICATVASTTGSESSTASEIITSSTM 996
Query: 2521 SIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDK 2580
S+ A S A+ +T S + + + + F S P T + ++
Sbjct: 997 SVSATASSTAS--STASEITMSSAAIPV----SSTAYETIRFSTAVSEP-VTASILALES 1049
Query: 2581 NTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGD 2640
S T T+++ P T K + +++T+ + T E +
Sbjct: 1050 TLAFTTVSN----TTTSSTVTSVPTTASTSGSKNTTACEATMSETT-IAAITASEDTTVS 1104
Query: 2641 EGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHT-QESLTAG 2699
V+ A+ P+ + P+ + L+ T T+ +T +++T
Sbjct: 1105 TQTSVI--AAESVPHTATKTPTDTTTASVSATVPKNNTLSVITSTPSTAPNTASKTMTTA 1162
Query: 2700 KATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGE 2759
T L T ++K + + + + T+ SG T ++ A
Sbjct: 1163 SKTTTTSTITSLPTTVFTTTSKITAGSEIPTASTTDSATTAISTKASGTTVESAPSTAPP 1222
Query: 2760 DKGIKALKESAKQTPAPAASVTGSRRRPRAPRE-SAQAIEDLAGFKDPAAGHTEESMTDD 2818
T + TG P A A E G + A + +T
Sbjct: 1223 TPAETTTASVPTTTSTTGSENTGHHTVSSVPTTVFATASESSTGSETTRASTSATEVTTA 1282
Query: 2819 KTTKIPCKSSPELEDTATSSKRRPRTRAQ 2847
TT + S +TA S + P T Q
Sbjct: 1283 MTTAMTTGS-----ETAVVSTKAPVTTTQ 1306
Score = 45.8 bits (107), Expect = 7e-04
Identities = 169/861 (19%), Positives = 278/861 (32%), Gaps = 152/861 (17%)
Query: 1051 TTHTHREPAGDGKSIRTFKESPKQILDPAARVTGMKKWPRTPKEEAQSLEDLAGFKELFQ 1110
T H R P + K+ + ES + + P +P E ++ E A
Sbjct: 462 TEHGERTPFANDKTTSSSAESTEH--GERTPLANENTTP-SPAEPTENRERTANENTTPS 518
Query: 1111 TPGPSE--ESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLALRKLTP 1168
GP+E E+ +EKTT + P E+ +T + K P + + + A K T
Sbjct: 519 PAGPTENRETTANEKTTLSPVE--PTENRETTANEKTTPSPAEPTENGQRTPFANEKTTS 576
Query: 1169 SAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGFK 1228
S+ +P E+ TP+ ++ +P E
Sbjct: 577 SSA------EPTEHGER-------TPL----------ANENTTPSPAE------------ 601
Query: 1229 ELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNL 1288
P E A KTT P + ++ D ++ S+ + G+ N
Sbjct: 602 -----PTENRERTANEKTTPSPAEPTENG--DRTPLANEKTTPSLAEPTENGQRTPFANE 654
Query: 1289 MPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDLTG 1348
++ A +P+ EE+ TP+ EN T S P T E A E+ T
Sbjct: 655 KTTSSSA----EPTEHEER-------TPL----ANENTTPSPAEP-TENRERTANENTTP 698
Query: 1349 FKELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSALK 1408
P E A KTT P E + T P P E + Q+ A +
Sbjct: 699 SP---AGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTE--NGQRTPFANE 753
Query: 1409 KLTQTSGE-TTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDL 1467
K T +S E T H ++ P + + L PA +R K P E
Sbjct: 754 KTTSSSAEPTEHGERTPLANENT----------TLSPAGPTENRERTANEKTTPFPAE-- 801
Query: 1468 AGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFAL 1527
P + T +E TT + + TP +++ + +
Sbjct: 802 ---------PTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTE-------N 845
Query: 1528 RKRTPSAGK--AMHTPKPAVSGEKNIYAFMGTPVQKLDLTEN--LTGSKRRLQTPKEKAQ 1583
KRTP A + + +P E+ A T + TEN T +++ Q P E +
Sbjct: 846 GKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTE 905
Query: 1584 ALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSL------ 1637
E A K T E + + TA S +P ++ + + +L
Sbjct: 906 NRESTANEK---TTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLMVDENLQAPFRQ 962
Query: 1638 GKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMES-----PKQILDSAASLTG 1692
G + + + + T E++ T S+ A S +I S+A++
Sbjct: 963 GSCAERPKDICATVASTTGSESSTASEIITSSTMSVSATASSTASSTASEITMSSAAIPV 1022
Query: 1693 SKRQLRTPKGKSEVPEDL-AGFIELFQTPSHTKESMTNEKTTKVSYRASQPDLVDTPTSS 1751
S T + + V E + A + L T + T S T +T S PT++
Sbjct: 1023 SSTAYETIRFSTAVSEPVTASILALESTLAFTTVSNTTTSSTVTS----------VPTTA 1072
Query: 1752 KPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQK------ 1805
++ + T S + T + E +T TP
Sbjct: 1073 STSGSKNTTACEATMSETTIAAITASEDTTVSTQTSVIAAESVPHTATKTPTDTTTASVS 1132
Query: 1806 ------------LDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKT 1853
P P + + T K +T P T TT + T
Sbjct: 1133 ATVPKNNTLSVITSTPSTAPNTASKTMTTASKTTTTSTITSL------PTTVFTTTSKIT 1186
Query: 1854 TKKILCKSPQSDPADTPTNTK 1874
+ + +D A T +TK
Sbjct: 1187 AGSEIPTASTTDSATTAISTK 1207
Score = 40.0 bits (92), Expect = 0.038
Identities = 189/961 (19%), Positives = 308/961 (32%), Gaps = 111/961 (11%)
Query: 857 KTSDTETEPSKTVSTANRSGRSTEFRNIQKL-PVESKSEETN----------TEIVECIL 905
+T++ PS T NR + E + P E++ N TE E
Sbjct: 353 RTANENNTPSPAEPTENRERTANENTTLSPAEPTENRERTANENTAPFPAGPTENREMTA 412
Query: 906 KRGQKATLLQQRREGEMKEIERPFETYKENIELKE---NDEKMKAMKRSRTWGQKCAPMS 962
+ GE E + E E E N+ + G++ +
Sbjct: 413 NENTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFAN 472
Query: 963 DLTDLKSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPTHTK 1022
D T S TE + T L ++ +P + ++ P P PT +
Sbjct: 473 DKTTSSSAESTEHGERTP-----LANENTTPSPAEPTENRERTANENTTPSPAG-PTENR 526
Query: 1023 QQL---KASLGKVGVKEELLAVGKFTRTSGETTHTHREPAGDGKSIRTFKESPKQILDPA 1079
+ K +L V E + T + +TT + EP +G+ RT + K A
Sbjct: 527 ETTANEKTTLSPVEPTEN-----RETTANEKTTPSPAEPTENGQ--RTPFANEKTTSSSA 579
Query: 1080 ARVTGMKKWPR-------TPKEEAQSLEDLAGFKELFQTPGPSEES-------MTDEKTT 1125
++ P +P E ++ E A K TP P+E + + +EKTT
Sbjct: 580 EPTEHGERTPLANENTTPSPAEPTENRERTANEKT---TPSPAEPTENGDRTPLANEKTT 636
Query: 1126 KIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEF-LALRKLTPSAGKAM---------- 1174
+ P TP + ++ S + EE LA TPS +
Sbjct: 637 P-SLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANEN 695
Query: 1175 LTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQL----QTPKEKAQALEDLAGFKEL 1230
TP PAG E T +K L P R+ +T A+ E+ G +
Sbjct: 696 TTPSPAGPTENREM----TANEKTTLFPAEPTENRERTANEKTTSSPAEPTEN--GQRTP 749
Query: 1231 F---QTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIR-----KADVEGEL 1282
F +T + E G+ T + ++ P PT ++R + E
Sbjct: 750 FANEKTTSSSAEPTEHGERTPLANENTTLSPAG-PTENRERTANEKTTPFPAEPTENRER 808
Query: 1283 LACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLT----ENLTGSKRRPQTPKE 1338
A N PS + + + + P + T E T S P E
Sbjct: 809 TANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAE 868
Query: 1339 EAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKR 1398
+ T P E A KTT+ P E + + T P P E R
Sbjct: 869 RTPLANENTTSSPA--EPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTENR 926
Query: 1399 DVQKELSALKKLTQTSGE-TTHTDKVPGGEDKSINA-FR-----ETAKQKLDPAASVTGS 1451
E +A + T + E T H + P D+++ A FR E K AS TGS
Sbjct: 927 ----EWTANENTTLSPAEPTEHEEMTPLMVDENLQAPFRQGSCAERPKDICATVASTTGS 982
Query: 1452 KRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQS 1511
+ T + ++ T T T + + + T+
Sbjct: 983 E--SSTASEIITSSTMSVSATASSTASSTASEITMSSAAIPVSSTAYETIRFSTAVSEPV 1040
Query: 1512 KRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYA----FMGTPVQKLDLTEN 1567
S+ ++ F + T S+ + SG KN A T + + +E+
Sbjct: 1041 TASILALESTLAFTTVSNTTTSSTVTSVPTTASTSGSKNTTACEATMSETTIAAITASED 1100
Query: 1568 LTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPD---K 1624
T S QT A+++ A T ++ + T V + P+ K
Sbjct: 1101 TTVS---TQTSVIAAESVPHTATKTPTDTTTASVSATVPKNNTLSVITSTPSTAPNTASK 1157
Query: 1625 NPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQIL 1684
++ + TS K+T S T + T+ S KA + +
Sbjct: 1158 TMTTASKTTTTSTITSLPTTVFTTTSKITAGSEIPTASTTDSATTAISTKASGTTVESAP 1217
Query: 1685 DSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTP----SHTKESMTNEKTTKVSYRAS 1740
+A P S + G + P + ES T +TT+ S A+
Sbjct: 1218 STAPPTPAETTTASVPTTTSTTGSENTGHHTVSSVPTTVFATASESSTGSETTRASTSAT 1277
Query: 1741 Q 1741
+
Sbjct: 1278 E 1278
Score = 36.2 bits (82), Expect = 0.54
Identities = 124/659 (18%), Positives = 203/659 (30%), Gaps = 104/659 (15%)
Query: 1111 TPGPSEESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLALRKLTPSA 1170
TP P+E + E+T P E + T E R++T +
Sbjct: 360 TPSPAEPTENRERTANENTTLSPAEPTENRERTANENTAPFPAGPTEN-----REMTANE 414
Query: 1171 GKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGFKEL 1230
+ +P E+ + G ++ +P E + E +
Sbjct: 415 NTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFAND- 473
Query: 1231 FQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMP 1290
+T + E G+ T + ++ P + PT ++R A N P
Sbjct: 474 -KTTSSSAESTEHGERTPLANENTTPSPAE-PTENRERT--------------ANENTTP 517
Query: 1291 SAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDLTGFK 1350
S + + E+ + T ++ E T S P + + T
Sbjct: 518 SPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSS 577
Query: 1351 ELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSALKKL 1410
T +A TT P E + T P P E D + L+ K
Sbjct: 578 SAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGD-RTPLANEKTT 636
Query: 1411 TQTSGETTHTDKVPGGEDKSINAFRE-TAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAG 1469
+ T + + P +K+ ++ E T ++ P A+ T A+P E+
Sbjct: 637 PSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLAN------ENTTPSPAEPTENRER 690
Query: 1470 LKELFQT-----PVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEF 1524
T P + T +EKTT + T + K S + + +
Sbjct: 691 TANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERT-ANEKTTSSPAEPTENGQRTP 749
Query: 1525 FALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQA 1584
FA K T S+ +P GE+ A T + TEN R +T EK
Sbjct: 750 FANEKTTSSSA------EPTEHGERTPLANENTTLSPAGPTEN------RERTANEKT-- 795
Query: 1585 LEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKE 1644
T E + ++TA S P +N
Sbjct: 796 ------------TPFPAEPTENRERTANENTTPSPAQPTEN------------------- 824
Query: 1645 ELLAVGKLTQTSGE-TTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGK 1703
G T + E TT + EPT +GK E +++S ++ RTP
Sbjct: 825 -----GDRTPLANEKTTPSLAEPTENGKRTPFANEK-----TTSSSAEPTEHAERTPLAN 874
Query: 1704 SEVPEDLAGFIELFQTPSHTKESMTNEKTTK-----VSYRASQPDLVDTPTSSKPQPKR 1757
A P+ +E NEKTT+ R S + TP ++P R
Sbjct: 875 ENTTSSPA-------EPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTENR 926
Score = 32.7 bits (73), Expect = 6.0
Identities = 92/451 (20%), Positives = 151/451 (33%), Gaps = 50/451 (11%)
Query: 838 NGNVAKTPRNTYKMTSLETKTSDTETEPSKTVSTANRSGRSTEFRNIQKL-PVESKSEET 896
N N +P T +T++ T PS T NR + E + + P E++
Sbjct: 493 NENTTPSPAEP---TENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTA 549
Query: 897 NTEIVEC---ILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDEKMKA---MKR 950
N + + GQ+ ++ E P E + EN A R
Sbjct: 550 NEKTTPSPAEPTENGQRTPFANEKTTSSSAE---PTEHGERTPLANENTTPSPAEPTENR 606
Query: 951 SRTWGQKCAPM-------SDLTDLKSLPDT-ELMKDTARGQN---LLQTQDHAKAPKSEK 999
RT +K P D T L + T L + T GQ + + A +E
Sbjct: 607 ERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEH 666
Query: 1000 GKITKMPCQSLQPEPINTPTHTKQQL---KASLGKVGVKE--ELLAVGKFTRTSGETTHT 1054
+ T + ++ P P PT +++ + G E E+ A K T E T
Sbjct: 667 EERTPLANENTTPSPAE-PTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEPTEN 725
Query: 1055 HREPAGDGKSIRTFKESPKQILDPAARVTGMKKWPRTPKEEAQSLE-----DLAGFKELF 1109
A + + SP + + R + +T A+ E LA
Sbjct: 726 RERTANEKTT-----SSPAEPTENGQRTPFANE--KTTSSSAEPTEHGERTPLANENTTL 778
Query: 1110 QTPGPSE--ESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLALRKLT 1167
GP+E E +EKTT + P E+ + + P + + + LA K T
Sbjct: 779 SPAGPTENRERTANEKTTPFPAE--PTENRERTANENTTPSPAQPTENGDRTPLANEKTT 836
Query: 1168 PSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGF 1227
PS + K + + P + + T ++ +P E + E A
Sbjct: 837 PSLAEPTENGKRTPFANEKTTSSSAEPTEHAE--RTPLANENTTSSPAEPTENRERTANE 894
Query: 1228 K--ELFQTPGHTEELVAAGKTTKIPCDSPQS 1256
K + P E A KTT P + ++
Sbjct: 895 KTTQFPAEPTENRESTANEKTTPFPAEPTEN 925
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 78.2 bits (191), Expect = 1e-13
Identities = 335/1701 (19%), Positives = 539/1701 (31%), Gaps = 224/1701 (13%)
Query: 1380 SADTP--TSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGED--------- 1428
++DTP +STR TP E R + S L +S E T + P G D
Sbjct: 99 TSDTPGVSSTRM---TPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEE 155
Query: 1429 --KSINAFRETAK-----------QKLD---PAASVTGSKRHPKTKEKAQ--PLEDLAGL 1470
S AF TA K+D P + T + P T E + G
Sbjct: 156 SISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGS 215
Query: 1471 KELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKR 1530
L P T K + E T + + P + TP + Q+ S E +L
Sbjct: 216 TPLTSMPASTMKVASSEAITLL---TTPVEISTPVTISAQASSS----PTTAEGPSLSNS 268
Query: 1531 TPSAGKAMHTPKP-----AVSGEKNIYAFM--GTPVQKLDLTE------NLTGSKRRLQT 1577
PS G T P VS E + + T + + TE G+ T
Sbjct: 269 APSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTST 328
Query: 1578 PKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSL 1637
E + L T + S+T T+ + S++P A + L ++L
Sbjct: 329 YTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTL 388
Query: 1638 GKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFME---SPKQILDSAASLT--- 1691
+ + V + S E + T T P + E SP D++ + +
Sbjct: 389 SEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPS 448
Query: 1692 -GSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQPDLVDTPTS 1750
GS P + V A L TP +K +T +T+ S ++ PTS
Sbjct: 449 EGSTPLTSMPVSTTPVASSEAS--NLSTTPVDSKTQVTT--STEASSSPPTAEVNSMPTS 504
Query: 1751 SKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPG 1810
+ + L +A + + + + T P + ++ T + P
Sbjct: 505 TPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSS--STTPEGTSIPT 562
Query: 1811 NLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPADTP 1870
+ P T + L + TP N T T+ + S ++ P
Sbjct: 563 STPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSN--TFVTTSSEASSSSTTAEGTSMP 620
Query: 1871 TNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDL 1930
T+T ++ V +A + A TP D NT V T E
Sbjct: 621 TSTYSERGTTITSMSVSTTLVA----SSEASTLSTTPV-------DSNTPVTTSTEATSS 669
Query: 1931 LGNLPGSKRRPQTPKEKAKALEDL---------AGFKELFQTPGHTEESMTDDKITEVSC 1981
G+ T E + L + + L TP T +T TE S
Sbjct: 670 STTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTS--TEASS 727
Query: 1982 KSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLT--QTSGKTTQTHRETAGDGKSI 2039
D PTS+ L + V + +L + + T+ T TH T+ +
Sbjct: 728 SPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCS 787
Query: 2040 KAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTD---- 2095
E + TP E + L + +P+ + STT
Sbjct: 788 PTTTEGTSMPIS-------------TPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSN 834
Query: 2096 ---DKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGD 2152
+T+++ P E PTST +TPL + L A ++ + T P D
Sbjct: 835 SPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTT---PVD 891
Query: 2153 EDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDL---------AGLKELFQT 2203
+ + + + P S G+ TP + PL + + + L T
Sbjct: 892 TSTPVT---NSTEARSSPTTS-EGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSAT 947
Query: 2204 PICTDKPTTHEKTTKIACRSPQP-DPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSV 2262
P+ T P T T+ A SP + PT + L V +A + +
Sbjct: 948 PVDTSTPVT---TSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLS 1004
Query: 2263 GKAMDTPKPAGGDEKDMKAFMGTPVQK-LDLPGNLPGSKRWPQTPKEKAQALEDLAGFKE 2321
+D+ P +A P + +P + P P T + + +
Sbjct: 1005 TTPVDSNTPL---TTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETST 1061
Query: 2322 LFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTP 2381
L TP D T ++ + S D P ST L V + + +
Sbjct: 1062 LSTTPA-DTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEAST 1120
Query: 2382 SAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFK 2441
+ +DT P + + ++ T + + + P P + L
Sbjct: 1121 LSTTPVDTSIPVTTSTEASSS--PTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEAN 1178
Query: 2442 ELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKL 2501
L TP ++ + TE S P E S+ PL + ++ P+A S+
Sbjct: 1179 TLSTTPVDSKTQVATS--TEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEA 1236
Query: 2502 TRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVD 2561
+ S T T T +++ + + L + + GS L T + L +
Sbjct: 1237 STLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGST--LLTSIPVSTTLVTSPE 1294
Query: 2562 FKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTK---RCPKTR-PRKEVKEELS 2617
L + P T+ + + ++ P E T TST R P T P S
Sbjct: 1295 ASTLLTTPVDTKGPVVT--SNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASS 1352
Query: 2618 AVERLTQTSGQ-------STHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPK 2670
A+ L+ T ST P + EG + + P+ P P
Sbjct: 1353 AISILSTTPVDNSTPVTTSTEACSSPTTS-EGTSMPNSNPSEGTTPLTSIPVSTTPVVSS 1411
Query: 2671 EKAQPLEDLAGFTELSETSGHTQE-SLTAGKATKIPCESPPLEVVDTTASTKRHLRTRVQ 2729
E + LS T T T+ +AT P + E + ST +T ++
Sbjct: 1412 EAST----------LSATPVDTSTPGTTSAEATSSPTTA---EGISIPTSTPSEGKTPLK 1458
Query: 2730 KVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRPRA 2789
+ V P A T T P + + S+ TPA S+ S
Sbjct: 1459 SIPVSNTPVANSEASTLSTTPVDSNSPV-----VTSTAVSSSPTPAEGTSIAIS-----T 1508
Query: 2790 PRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKV 2849
P E + A+ T IP ++ S P + V
Sbjct: 1509 PSEGSTAL-----------------------TSIPVSTTTVASSEINSLSTTPAVTSTPV 1545
Query: 2850 EVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPK 2909
+ + + T+ + T EG T P L V+ S A
Sbjct: 1546 TTYSQASS----SPTTADGTSMQTSTYSEGS-TPLTSLPVSTML----VVSSE----ANT 1592
Query: 2910 EKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVE 2969
P++ +Q TE ++ A+ +S TP G PL S V P
Sbjct: 1593 LSTTPIDSK------TQVTASTEASSSTTAEG-SSMTISTPSEGSPLLTSIPVSTTPVAS 1645
Query: 2970 PVGDVVSTRDPVKSQSKSNTS 2990
P +ST PV S S TS
Sbjct: 1646 PEASTLST-TPVDSNSPVITS 1665
Score = 77.4 bits (189), Expect = 2e-13
Identities = 427/2238 (19%), Positives = 690/2238 (30%), Gaps = 291/2238 (13%)
Query: 841 VAKTPRNTYKMTSLETKTSDTETEPSKT-VSTANRSGRSTEFRNIQKLPVESKSEETNTE 899
+A P +T + S E T T SKT V+T+ + + +P + E + T
Sbjct: 1162 LASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERS-TP 1220
Query: 900 IVECILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDEKMKAMKRSRTWGQKCA 959
+ ++ A+ + P T E E + + G
Sbjct: 1221 LTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGS--- 1277
Query: 960 PMSDLTDLKSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPT 1019
T L S+P + + + LL T K P +++ P + E + PT
Sbjct: 1278 -----TLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPA---EGTSMPT 1329
Query: 1020 HTKQQLKASLGKVGVKEELLAVGKF-----TRTSGETTHTHREPAGDGKSIRTFKESPKQ 1074
T + + L + V L+A T T T A + P
Sbjct: 1330 STYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNS 1389
Query: 1075 ILDPAARVTGMKKWP--RTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACKSP 1132
+P+ T + P TP +++ L+ TPG + T TT P
Sbjct: 1390 --NPSEGTTPLTSIPVSTTPVVSSEA-STLSATPVDTSTPGTTSAEATSSPTTAEGISIP 1446
Query: 1133 PPESVDTPTSTKQWPKRSLRKADVEEEFLALRKLTPSAGKAMLT-----PKPAGGDEKDI 1187
+ T K P + A+ E L+ + ++ T P PA G I
Sbjct: 1447 TSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAI 1506
Query: 1188 KAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTT 1247
TP + ++P S T + + L+ + TP T ++ TT
Sbjct: 1507 S----TPSEGSTALTSIPVS-----TTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTT 1557
Query: 1248 KIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEK 1307
S + T P ++ E L+ + T S +
Sbjct: 1558 ADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAE 1617
Query: 1308 DIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGK 1367
+ + TP + L ++ S +P+ L TP + V
Sbjct: 1618 GSSMTISTPSEGSPLLTSIPVSTTPVASPEAST-----------LSTTPVDSNSPVIT-- 1664
Query: 1368 TTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGE 1427
+T++ +P E PTST + +TPL V+ A ++ S TT D
Sbjct: 1665 STEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLS--TTPVD------ 1716
Query: 1428 DKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDL---------AGLKELFQTPV 1478
+ + + + P S S + E PL + + L TP+
Sbjct: 1717 --NSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPI 1774
Query: 1479 CTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAM 1538
T P T T + + + PTS+ + L V A + + + +
Sbjct: 1775 DTSTPVT-TSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPV 1833
Query: 1539 HTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTR 1598
+ P V+ + TP + G+ TP E + AL + +
Sbjct: 1834 DSNSPVVTS--TAVSSSPTPAE---------GTSIATSTPSEGSTALTSIPVSTTTVASS 1882
Query: 1599 G----HTEESMTNDKTAKVACKSSQP---DPDKNPASSKRRLKTSLGKVGVKEELLAVGK 1651
T ++T+ A SS P D P S+ R + L + V +A +
Sbjct: 1883 ETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSE 1942
Query: 1652 LTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGKSEVPEDLA 1711
+ S T T T ++ S++ T + TP
Sbjct: 1943 INTLSTTLADTRTPVTTYSQA-------------SSSPTTADGTSMPTPAYSE------- 1982
Query: 1712 GFIELFQTPSHTKESMTNEKTT--KVSYRASQPDLVDTPTSSKPQPK--RSLRKADTEEE 1767
G L P T +++E +T S P T SS P S++ + E
Sbjct: 1983 GSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSE- 2041
Query: 1768 FLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQ 1827
+ TP AG + T E ++T TPV Q N ++
Sbjct: 2042 -----RTTPLAGMPVSTTLVVSSEGNTLST---TPVDSKTQVTNSTEASSSATAEGSSMT 2093
Query: 1828 ALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVE 1887
G L P + P + + + P T T P + + ++
Sbjct: 2094 ISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPT-EGTSMQ 2152
Query: 1888 EEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEK 1947
+ R+ TP + T A I+T TPV+ + N ++ P T +
Sbjct: 2153 TSTYSDRR-TPLTSMPVSTTVVA---SSAISTLSTTPVDTSTPVTNSTEARSSPTTSE-- 2206
Query: 1948 AKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLGKVG 2007
G TP T ++ + PV T +S
Sbjct: 2207 --------GTSMPTSTPSEGSTPFTSMPVSTM--------PVVTSEASTL---------- 2240
Query: 2008 VKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPK 2067
PV T + T T T +G SI S GT TP
Sbjct: 2241 ---SATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSE---------GT-------TPL 2281
Query: 2068 EEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPP--ESMDTPTSTRRRPKTPL 2125
L E+ T T + TT SPPP E PTST TPL
Sbjct: 2282 TSIPVSHTLVANSEV-STLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPL 2340
Query: 2126 GKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRE--TAKQKLDPAASVTGSKRQPRT 2183
+ + + A +T+ P D + + + ++ D + T + + T
Sbjct: 2341 TRMPVSTTMVA---SFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGST 2397
Query: 2184 PKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSL 2243
P + P+ + + T T T+ TT S GT P S+ +
Sbjct: 2398 PL-TSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTT 2456
Query: 2244 RKAD--------VEEESLALRKRTPSVGKAMDTPKPAGGD---EKDMKAFMGTPVQKLDL 2292
A V E+ L M T A +D+ + T + L
Sbjct: 2457 PLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTL 2516
Query: 2293 PGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDT 2352
++P S TP +A T D + +T+I+ + +
Sbjct: 2517 LTSIPVS----TTPVASPEA--------STLSTTPVDSNSPVVTSTEISSSATSAEGTSM 2564
Query: 2353 PASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLD 2412
P ST LR V + LA + + + +DT P + + + +P D
Sbjct: 2565 PTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSS----SPTTAKD 2620
Query: 2413 LLGNLPGSKRQPQTPKEKAEALEDLV---------GFKELFQTPGHTEESMTDDKITEVS 2463
++P S TP E + +L ++ L TP T +T T S
Sbjct: 2621 T--SMPIS-----TPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSS 2673
Query: 2464 CKSPQPESFKTSRSSKQRLKIPLVKVD-----------MKEEPLAVSKLTRTSGETTQTH 2512
+ + S TS ++ + + V + P+ S TS E + +
Sbjct: 2674 PTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSP 2733
Query: 2513 TEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHT 2572
T G S I +P P S+ S + + E + VD +
Sbjct: 2734 TTAEGTSMRI----STPSDGSTPLTSILVSTLPVAS-SEASTVSTTAVDTSIPVTTSTEA 2788
Query: 2573 EESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHT 2632
S T + T +P +P ++T+T P E + TS T +
Sbjct: 2789 SSSPTTAEVTSMPTSTP----SETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTS 2844
Query: 2633 HKEPASGD--EGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELS-ETS 2689
K +S EGI V A + + P P A E A L T + TS
Sbjct: 2845 TKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSE-ASTLSTTPVDTSIPVTTS 2903
Query: 2690 GHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGET 2749
S T + T +P ST + T + + V P A T T
Sbjct: 2904 TEGSSSPTTAEGTSMP------------ISTPSEVSTPLTSILVSTVPVAGSEASTLSTT 2951
Query: 2750 TDADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAG 2809
+ P + +A+ T P S G RR P + + +A +
Sbjct: 2952 PVDTRTPVTTSAEASSSPTTAEGTSMP-ISTPGERRTPLT--SMSVSTMPVASSEASTLS 3008
Query: 2810 HTEESMTDDKTTKIPCKSSP---ELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSG 2866
T + TT SSP E S+ T + V +A+ + + S
Sbjct: 3009 RTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLS- 3067
Query: 2867 ETTHTD-KEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELS 2925
TT D PV + PA+ P + ++ LS
Sbjct: 3068 -TTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLS 3126
Query: 2926 QTP--------GHTEELANGAADSFTSAPKQTPDSGK-PLKISRRVLRAPKVEPVGD--V 2974
TP TE ++ TS P TP G PL PV V
Sbjct: 3127 TTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYM----------PVSTMLV 3176
Query: 2975 VSTRDPVKSQSKSNTSLP 2992
VS+ D S + +TS P
Sbjct: 3177 VSSEDSTLSATPVDTSTP 3194
Score = 75.9 bits (185), Expect = 6e-13
Identities = 448/2370 (18%), Positives = 710/2370 (29%), Gaps = 310/2370 (13%)
Query: 793 SGEEPLLPTSESFGGNVFFSAQNAAKQPSDKCSASP----PLRRQCIRENGNVAKTPRNT 848
+ E +PTS G+ ++ A+ P S P+ + + T
Sbjct: 318 TAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTT 377
Query: 849 YKMTSLETKTSDTETEPSKTVSTANRSGRSTEFRNIQKLPVESKSEETNTEIVECILKRG 908
+ TS+ T T + P + + S+E +PV+SK+ T
Sbjct: 378 AEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTA 437
Query: 909 QKATLLQQR-REGEMKEIERPFET----YKENIELKENDEKMKAMKRSRTWGQKCAPMSD 963
+ ++ EG P T E L K + T P ++
Sbjct: 438 EDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAE 497
Query: 964 L------------TDLKSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKITKMPCQSLQ 1011
+ T L S+ + + ++ L T P + + + S
Sbjct: 498 VNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASS---SSTT 554
Query: 1012 PEPINTPTHTKQQLKASLGKVGVKEELLAVGK-------------FTRTSGETTHTHREP 1058
PE + PT T + L + V L+ + F TS E + +
Sbjct: 555 PEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTA 614
Query: 1059 AGDGKSIRTFKESPKQILDPAARVTGM--------------KKWPRTPKEEAQSLEDLA- 1103
G T+ E I + T + P T EA S A
Sbjct: 615 EGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAE 674
Query: 1104 --GFKELFQTPGPSEESMTDEKTTKIACK-----SPPPESVDTPTSTKQWPKRSLRKADV 1156
T G + + TT +A S P TP +T S AD
Sbjct: 675 GTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTAD- 733
Query: 1157 EEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKE 1216
++ TPS G LT P + + T + L+ T + + T E
Sbjct: 734 ---GASMPTSTPSEGSTPLTSMP-------VSKTLLTSSEASTLSTTPLDTSTHITTSTE 783
Query: 1217 KAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSD-----PVDTPTSTKQRPKR 1271
+ + G TP L+ + + P SP++ PVD+ + +
Sbjct: 784 ASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEV 843
Query: 1272 SIRKADVEGELLACRNLMPSAGKAMHTPKP---SVGEEKDIIIFVGTPVQKLDLTENLTG 1328
S EG + S G+ T P ++ I TPV N T
Sbjct: 844 SSSPTPAEGTSMPTSTY--SEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTE 901
Query: 1329 SKRRP----------QTPKEEAQALEDL---------TGFKELFQTPGHTEEAVAAGKTT 1369
++ P TP E + L + + + L TP T V TT
Sbjct: 902 ARSSPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPV----TT 957
Query: 1370 KMPCESSP--PESADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGE 1427
SSP E PTST + TPL V L A + + S TT D
Sbjct: 958 STEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLS--TTPVDS----- 1010
Query: 1428 DKSINAFRETAKQKLDPAASVTGSKRHPKT-KEKAQPLEDL---------AGLKELFQTP 1477
N T+ + P + G+ T E + PL + + L TP
Sbjct: 1011 ----NTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTP 1066
Query: 1478 VCTDKP-TTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGK 1536
T P TT+ + + + + D PTS+ + L V V + + +
Sbjct: 1067 ADTSTPVTTYSQAS--SSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTT 1124
Query: 1537 AMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGFKEL-F 1595
+ T P T + G+ P E L + L
Sbjct: 1125 PVDTSIPVT-----------TSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVV 1173
Query: 1596 QTRGHTEESMTNDKTAKVA--CKSSQPDPDKN----PASSKRRLKTSLGKVGVKEELLAV 1649
+ +T + D +VA ++S P P P S+ T L + V+ +A
Sbjct: 1174 SSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVAS 1233
Query: 1650 GKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGKSEVPED 1709
+ + S T T T ++ + + L ++ + GS P + V
Sbjct: 1234 SEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSP 1293
Query: 1710 LAGFIELFQTPSHTKESMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFL 1769
A L TP TK + + +VS + + PTS+ + + L +
Sbjct: 1294 EAS--TLLTTPVDTKGPVVT--SNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLV 1349
Query: 1770 AFRKQTPSAGKAMHTPKPAVGEEKDIN---TFLGTPVQKLD-QPGNLPGSNRRLQTRKEK 1825
A + + + P + + T GT + + G P ++ + T
Sbjct: 1350 ASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVV 1409
Query: 1826 AQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKAD 1885
+ L+ TP T + T P S P++ T K P + A+
Sbjct: 1410 SSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVAN 1469
Query: 1886 VEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPK 1945
E L+ TP + AV TP E + + P T
Sbjct: 1470 SEASTLS---TTPVDSNSPVVTSTAVSSSP-------TPAEGTSIAISTPSEGSTALTSI 1519
Query: 1946 EKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLGK 2005
+ + L TP T +T + P +S Q S G
Sbjct: 1520 PVSTTTVASSEINSLSTTPAVTSTPVT-------TYSQASSSPTTADGTSMQTSTYSEGS 1572
Query: 2006 VGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRT 2065
+ LPV + S + T T D K+ + +A + G T
Sbjct: 1573 TPLTS--LPVSTMLVVSSE-ANTLSTTPIDSKT----QVTASTEASSSTTAEGSSMTIST 1625
Query: 2066 PKEEAQSLEDLAGFKELFQTPDHTEESTTD-------DKTTKIACKSPPPESMDTPTSTR 2118
P E + L + +P+ + STT +T+++ P E PTST
Sbjct: 1626 PSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTY 1685
Query: 2119 RRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSK 2178
+TPL T+ T + I+ T P + T ++
Sbjct: 1686 TEGRTPL-----------------TSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEAR 1728
Query: 2179 RQPRTPKGKAQPLEDLA-GLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKP 2237
P T +G + P + G L P+ T + E +T A PV T T
Sbjct: 1729 SSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTST---- 1784
Query: 2238 QSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGD---EKDMKAFMGTPVQK----- 2289
+ E ++ T S G T P + TPV
Sbjct: 1785 ----EATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVV 1840
Query: 2290 -----LDLPGNLPGSKRWPQTPKEKAQALEDL-----AGFKELFQTPGTDKPTTDEKTTK 2339
P G+ TP E + AL + T T T T
Sbjct: 1841 TSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTT 1900
Query: 2340 IACKSPQPDPVD---TPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSD 2396
A S P D P ST + + L V +A + + DT P +
Sbjct: 1901 YAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTY 1960
Query: 2397 EKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTD 2456
+ ++ + GS P T + L L TP T T
Sbjct: 1961 SQASSSPTTADGTSMPTPAYSEGS--TPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATT 2018
Query: 2457 DKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPT 2516
S + S +TS S++ PL + P++ + + + G T T P
Sbjct: 2019 STEGSSSPTTAGGTSIQTSTPSER--TTPLAGM-----PVSTTLVVSSEGNTLS--TTPV 2069
Query: 2517 GDSKSIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDL-VDFKELFSAPGHTEES 2575
+ E+ +A+ GS + E + L + + + S T +
Sbjct: 2070 DSKTQVTNSTEA-----SSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLST 2124
Query: 2576 MTIDKN------TKIPCKSPPPELTDTATST---KRCPKT-RPRKEVKEELSAVERLTQT 2625
+D N T++ P E T TST +R P T P SA+ L+ T
Sbjct: 2125 TPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTT 2184
Query: 2626 S-------GQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPKE----KAQ 2674
ST P + EG + + P P P E A
Sbjct: 2185 PVDTSTPVTNSTEARSSPTT-SEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSAT 2243
Query: 2675 PLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVK 2734
P++ T TS S T + T IP + T+ H +V
Sbjct: 2244 PVDTSTPVT----TSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTL 2299
Query: 2735 EEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAP---------AASVTGSRR 2785
T + T + P E + S TP A+ T +
Sbjct: 2300 STTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLS 2359
Query: 2786 RPRAPRESAQAIEDLAGFKDPAAGHTE---ESMTDDKT--TKIPCKSSPELEDTATSSKR 2840
A + AG A T + ++ T T +P + P + A++
Sbjct: 2360 TTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHST 2419
Query: 2841 RPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIG 2900
P + V E + T+ E T P EG T P G
Sbjct: 2420 TPVDTSTPVTTSTE----ASSSPTTAEGTSIPTSPPSEGT-TPLASMPVSTTPVVSSEAG 2474
Query: 2901 SRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKPLKISR 2960
+ P + + P + + E S +P E++ P T G L S
Sbjct: 2475 T--LSTTPVDTSTP---MTTSTEASSSPTTAEDIV---------VPISTASEGSTLLTSI 2520
Query: 2961 RVLRAPKVEPVGDVVSTRDPVKSQSKSNTS 2990
V P P +ST PV S S TS
Sbjct: 2521 PVSTTPVASPEASTLST-TPVDSNSPVVTS 2549
Score = 75.1 bits (183), Expect = 1e-12
Identities = 361/1905 (18%), Positives = 589/1905 (30%), Gaps = 286/1905 (15%)
Query: 1260 DTP--TSTKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPV 1317
DTP +ST+ P S ++ + L PS+ + T P+ E D+ + TP
Sbjct: 101 DTPGVSSTRMTPTESRTTSESTSD---STTLFPSSTE--DTSSPTTPEGTDVPM--STPS 153
Query: 1318 QKLDLTENLTGSKRRPQT-PKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESS 1376
+ E+++ + T P +A LT +K TP T ++ TT
Sbjct: 154 E-----ESISSTMAFVSTAPLPSFEAYTSLT-YKVDMSTPLTTSTQASSSPTT------- 200
Query: 1377 PPESADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRE 1436
PES P ST + TPL ++ K+ + T T V +I+A
Sbjct: 201 -PESTTIPKSTNSEGSTPLTSMP-----ASTMKVASSEAITLLTTPVEISTPVTISAQAS 254
Query: 1437 TAKQKLDPAASVTGSKRHPKTKEKAQPLEDL----AGLKELFQTPVCTD----------- 1481
++ + + + T PL + + L TP T+
Sbjct: 255 SSPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASS 314
Query: 1482 KPTTHEKT---TKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAM 1538
PTT E T T TP S+ P + + + + + T + ++
Sbjct: 315 SPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSL 374
Query: 1539 HTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTR 1598
T A S + + TP+ + ++ L S T + K T
Sbjct: 375 PTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIPVDS-------KTFVTTA 427
Query: 1599 GHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKE-ELLAVGKLTQTSG 1657
S T + +A +S P P +S T + V TQ +
Sbjct: 428 SEASSSPTTAEDTSIA--TSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKTQVTT 485
Query: 1658 ETTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELF 1717
T + + PT + SM S + + LT S P SE L
Sbjct: 486 STEASSSPPTAEVNSMPTSTPS-----EGSTPLT-SMSVSTMPVASSEAS-------TLS 532
Query: 1718 QTPSHTKESMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPS 1777
TP T +T +++ S ++ P+ PTS+ + L + +
Sbjct: 533 TTPVDTSTPVTT--SSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVV----SSE 586
Query: 1778 AGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEEL----- 1832
A TP D NTF+ T + G++ T E+ + +
Sbjct: 587 ASTTSTTP-------ADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTT 639
Query: 1833 ----TGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEE 1888
+ L TP N T T+ + S ++ PT+T L V
Sbjct: 640 LVASSEASTLSTTPVDSN--TPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNT 697
Query: 1889 EFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKA 1948
+A + A TP D +T V T E G+ TP E +
Sbjct: 698 TLVA----SSEASTLSTTP-------VDTSTPVTTSTEASSSPTTADGASMPTSTPSEGS 746
Query: 1949 KALEDLAGFKELF---------QTPGHTEESMTDDKITEVSCKSPQPD----PVKTPTSS 1995
L + K L TP T +T TE SC + P+ TP+
Sbjct: 747 TPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTS--TEASCSPTTTEGTSMPISTPSEG 804
Query: 1996 KQRL---KISLGKVGVKE----EVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQ 2048
L +S+ V E PV + + T + T +G S
Sbjct: 805 SPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTS---------- 854
Query: 2049 MLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPP 2108
+ + Y G R P T + +L + L TP + ST +T+
Sbjct: 855 -MPTSTYSEG--RTPLTSMPVSTTLVATSAISTLSTTP--VDTSTPVTNSTEARSSPTTS 909
Query: 2109 ESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKL 2168
E PTST TPL + T V E + ++ T
Sbjct: 910 EGTSMPTSTPGEGSTPL--------------TSMPDSTTPVVSSEARTLSA---TPVDTS 952
Query: 2169 DPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDP 2228
P + T + P T +G + P TP+ T P +H + P
Sbjct: 953 TPVTTSTEATSSPTTAEGTSIP----TSTPSEGTTPL-TSTPVSHTLVANSEASTLSTTP 1007
Query: 2229 VGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQ 2288
V + T ++ S E G +M T P+ G TP+
Sbjct: 1008 VDSNTPLTTSTEASSPPPTAE-------------GTSMPTSTPSEG---------STPLT 1045
Query: 2289 KLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPD 2348
++ + + S T D T ++ + S D
Sbjct: 1046 RMPVSTTMVASSE------------------TSTLSTTPADTSTPVTTYSQASSSSTTAD 1087
Query: 2349 PVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPV 2408
P ST L V + + + + +DT P + + ++ T
Sbjct: 1088 GTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSS--PTTA 1145
Query: 2409 QKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQ 2468
+ + + P P + L L TP ++ + TE S P
Sbjct: 1146 EGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATS--TEASSPPPT 1203
Query: 2469 PESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKES 2528
E S+ PL + ++ P+A S+ + S T T T +++ + +
Sbjct: 1204 AEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTA 1263
Query: 2529 PKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKS 2588
L + + GS L T + L + L + P T+ + + ++
Sbjct: 1264 EGTSLPTSTTSEGS--TLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVV--TSNEVSSSP 1319
Query: 2589 PPPELTDTATST---KRCPKTR-PRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIK 2644
P E T TST R P T P SA+ L+ T P +
Sbjct: 1320 TPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTT----------PVDNSTPVT 1369
Query: 2645 VLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFT------ELSETSGHTQESLTA 2698
+ +P E + P E PL + T E S S ++ T
Sbjct: 1370 TSTEACS---SPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTP 1426
Query: 2699 GKATKIPCESP-PLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPA 2757
G + SP E + ST +T ++ + V P A T T P
Sbjct: 1427 GTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPV 1486
Query: 2758 GEDKGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESM-T 2816
+ + S+ TPA S+ S P E + A+ + A S+ T
Sbjct: 1487 -----VTSTAVSSSPTPAEGTSIAIS-----TPSEGSTALTSIPVSTTTVASSEINSLST 1536
Query: 2817 DDKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEEL--LAVGKLTQTSGETTHTDKE 2874
T P + + + T++ + E L L V + S E
Sbjct: 1537 TPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTT 1596
Query: 2875 PVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEEL 2934
P+ + K A AE GS P E PL L+ P T +
Sbjct: 1597 PI-DSKTQVTASTEASSSTTAE---GSSMTISTPSE-GSPL--------LTSIPVSTTPV 1643
Query: 2935 ANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKV---------------EPVGDVVSTRD 2979
A+ A + ++ P DS P+ S V +P P+ +
Sbjct: 1644 ASPEASTLSTTP---VDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTT 1700
Query: 2980 PVKSQSKSNTSLPPLPFKRGGGKDGSVTGTKRLRCMPAPEEIVEELPASKKQRVAPRARG 3039
PV S + S S P+ VT + R P E ++ + P
Sbjct: 1701 PVASSAISTLSTTPV------DNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSI 1754
Query: 3040 KSSEPVVIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVP 3084
S V+ + SA I+ + + ++ T+ S+P
Sbjct: 1755 PVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIP 1799
Score = 65.9 bits (159), Expect = 6e-10
Identities = 360/1905 (18%), Positives = 583/1905 (30%), Gaps = 248/1905 (13%)
Query: 1205 PGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDT--- 1261
PG TP E E + LF + + T +P +P + + +
Sbjct: 103 PGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMA 162
Query: 1262 -----PTSTKQRPKRSIRKADVEGELLAC--RNLMPSAGKAMHTPKPSVGEEKDIIIFVG 1314
P + + K D+ L + P+ ++ PK + E + +
Sbjct: 163 FVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMP 222
Query: 1315 TPVQKLDLTENLTGSKRRPQTPKE-------EAQALEDLTGFKELFQTPGHTEEAVAAGK 1367
K+ +E +T TP E AQA T + P + A + G
Sbjct: 223 ASTMKVASSEAIT----LLTTPVEISTPVTISAQASSSPT----TAEGPSLSNSAPSGGS 274
Query: 1368 T--TKMPCE------------SSPPESADTPTSTRRQPKTPLEKRDVQKELSALKKLTQT 1413
T T+MP S+ P + + P T T E +++ T T
Sbjct: 275 TPLTRMPLSVMLVVSSEASTLSTTPAATNIPVIT----STEASSSPTTAEGTSIPTSTYT 330
Query: 1414 SGETTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGLKEL 1473
G T T + + + +D + VT S A+ L
Sbjct: 331 EGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSE 390
Query: 1474 FQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPS 1533
TP+ +T + A + PVD+ T S+ S E+ ++ TPS
Sbjct: 391 GSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDT--SIATSTPS 448
Query: 1534 AGKAMHTPKP------AVSGEKNIYAFMGTPV-QKLDLTENLTGS---------KRRLQT 1577
G T P A S N+ TPV K +T + S T
Sbjct: 449 EGSTPLTSMPVSTTPVASSEASNLST---TPVDSKTQVTTSTEASSSPPTAEVNSMPTST 505
Query: 1578 PKEKAQALEDL-------AGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSK 1630
P E + L + A + + + S +++ + S+ P+ P S+
Sbjct: 506 PSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTP 565
Query: 1631 RRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHT-----------EPTGDGKSMKAFMES 1679
T L + V L+ + + TS ++T T +G SM S
Sbjct: 566 SEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYS 625
Query: 1680 PKQILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRA 1739
+ ++ S++ + S P D TP T T+ TT
Sbjct: 626 ERGTTITSMSVSTTLVASSEASTLSTTPVD-------SNTPVTTSTEATSSSTTAEGTSM 678
Query: 1740 SQPDLVDTPTSSKPQPKRSLRKADTEEEFLA---FRKQTPSAGKAMHTPKPAVGEEKDIN 1796
+ T P + A +E L+ TP + P + +
Sbjct: 679 PTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMP 738
Query: 1797 TFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEEL-TGFRELFQTPCTDNPTTDEKTTK 1855
T TP + ++P S L + + + L T T + +PTT E T+
Sbjct: 739 T--STPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSM 796
Query: 1856 KILCKSPQS------DPADTPTNTKQRPKRSLKKADVEEEFLAFRKL----TPSAGKAMH 1905
I S S + TP + + S D ++ TP+ G +M
Sbjct: 797 PISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMP 856
Query: 1906 TPKAAVGEEKDINTFVGTPV---EKLDLLGNLPGSKRRPQTPKEKAKALEDLA-GFKELF 1961
T + G + V T + + L P P T +A++ + G
Sbjct: 857 TSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPT 916
Query: 1962 QTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQT 2021
TPG +T PD TP S + +S PV T
Sbjct: 917 STPGEGSTPLTS-----------MPDST-TPVVSSEARTLS---------ATPVDTSTPV 955
Query: 2022 SGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKE 2081
+ T T T +G SI S GT TP L E
Sbjct: 956 TTSTEATSSPTTAEGTSIPTSTPSE---------GT-------TPLTSTPVSHTLVANSE 999
Query: 2082 LFQTPDHTEESTTDDKTTKIACKSPPP--ESMDTPTSTRRRPKTPLGKRDIVEELSALKQ 2139
T T + TT SPPP E PTST TPL + + + A
Sbjct: 1000 A-STLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVA--- 1055
Query: 2140 LTQTTHTDKVPGDEDKGINVFRETAKQK--LDPAASVTGSKRQPRTPKGKAQPLEDLAGL 2197
++T+ P D + + + + D + T + + TP L
Sbjct: 1056 SSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVS 1115
Query: 2198 KE---LFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLA 2254
E L TP+ T P TT S GT P S+ + A + +
Sbjct: 1116 SEASTLSTTPVDTSIPV----TTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVST-- 1169
Query: 2255 LRKRTPSVGKAMDTPKPAGGDEK-----DMKAFMGTPVQKL-DLPGNLPGSKRWPQTPKE 2308
T V +T D K +A P ++ +P + PG + P T
Sbjct: 1170 ----TLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMP 1225
Query: 2309 KAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKAD 2368
+ L +P D T + + + + P ST L
Sbjct: 1226 VRHTPVASSEASTLSTSP-VDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIP 1284
Query: 2369 VEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPK 2428
V + + + +DT P V+ + ++ TP + + + R P T
Sbjct: 1285 VSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSS--PTPAEGTSMPTSTYSEGRTPLTSI 1342
Query: 2429 EKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSP-QPESFKTSRSSKQRLKIPLV 2487
L L TP +T TE +C SP E S+ PL
Sbjct: 1343 PVNTTLVASSAISILSTTPVDNSTPVTTS--TE-ACSSPTTSEGTSMPNSNPSEGTTPLT 1399
Query: 2488 KVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLR 2547
+ + P+ S+ + S T T T +++ + + + I P ++ + + L+
Sbjct: 1400 SIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSS-PTTAEGISIPTSTPSEGKTPLK 1458
Query: 2548 TRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCP--- 2604
+ + + P E+ T+ + P S P +T TA S+ P
Sbjct: 1459 S--------------IPVSNTPVANSEASTL---STTPVDSNSPVVTSTAVSSSPTPAEG 1501
Query: 2605 -----KTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEE 2659
T V T S + PA + Q + +P
Sbjct: 1502 TSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASS---SPTTA 1558
Query: 2660 EPSRRRPRAPKEKAQPLEDLAGFT------ELSETSGHTQESLTAGKATKIPCESPPLEV 2713
+ + + E + PL L T E + S +S T A+ S E
Sbjct: 1559 DGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEG 1618
Query: 2714 VDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQT 2773
T ST + + V P A T T P I + + S+ T
Sbjct: 1619 SSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPV-----ITSTEVSSSPT 1673
Query: 2774 PAPAASV-TGSRRRPRAPRESAQA-IEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPEL 2831
PA S+ T + R P S +A T + TT +SSP
Sbjct: 1674 PAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTT 1733
Query: 2832 EDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKR 2891
+ + P LT TT PV + + P
Sbjct: 1734 SEGTSMPNSTPSE------------GTTPLTSIPVSTT-----PVLSSEASTLSATPIDT 1776
Query: 2892 KLDAEDVIGSRRQPRAPKEKAQPLEDLA-SFQELSQTPGHTEELANGAADSFTSAPKQTP 2950
+ P + + P L+ L+ TP +AN A + ++ P
Sbjct: 1777 STPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTP---V 1833
Query: 2951 DSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLP 2995
DS P+ S V +P G ++T P S+ +T+L +P
Sbjct: 1834 DSNSPVVTSTAVSSSP-TPAEGTSIATSTP----SEGSTALTSIP 1873
Score = 56.2 bits (134), Expect = 5e-07
Identities = 333/1725 (19%), Positives = 529/1725 (30%), Gaps = 269/1725 (15%)
Query: 852 TSLETKTSDTETEPSKTVSTANRSGRSTEFRNIQKLPVESKSEETN-TEIVECILKRGQK 910
TS++T T T P + + S+E + PV+SK++ TN TE G
Sbjct: 2032 TSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSS 2091
Query: 911 ATLLQQRREGEMKEIERPFET---------------YKENIELKENDEKMKAMKRSRTWG 955
T+ EG P T N + + E + +
Sbjct: 2092 MTI-SAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTS 2150
Query: 956 QKCAPMSDL-TDLKSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKITKMPCQSLQPEP 1014
+ + SD T L S+P + + ++ L T P + + P S E
Sbjct: 2151 MQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTS---EG 2207
Query: 1015 INTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETTHTHREPAGDGKSIRTFKESPKQ 1074
+ PT T + + V + + + S T ++ + +
Sbjct: 2208 TSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGT 2267
Query: 1075 ILDPAARVTGMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACKSPPP 1134
+ + G P T + +L + L TP S T T SPPP
Sbjct: 2268 SIPTSTLSEGTT--PLTSIPVSHTLVANSEVSTLSTTPVDSNTPFT----TSTEASSPPP 2321
Query: 1135 --ESVDTPTSTKQWPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEKDIKAFMG 1192
E PTST L + V +A S + L+ PA
Sbjct: 2322 TAEGTSMPTSTSSEGNTPLTRMPVSTTMVA------SFETSTLSTTPAD---------TS 2366
Query: 1193 TPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCD 1252
TPV AG+ P + P G L P T +V++ +T
Sbjct: 2367 TPVTTYSQAGSSPTTADDTSMPTSTYSE-----GSTPLTSVPVSTMPVVSSEASTH---- 2417
Query: 1253 SPQSDPVDTPTSTKQRPKRSIRKADVEGELLAC----RNLMPSAGKAMHTPKPSVGEEKD 1308
+ PVDT T + S EG + P A + T P V E
Sbjct: 2418 --STTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTT-PVVSSEAG 2474
Query: 1309 IIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDLTGFKELFQ------TPGHTEEA 1362
+ TPV T + P T ++ + + L TP + EA
Sbjct: 2475 TLST--TPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEA 2532
Query: 1363 VAAGKT-----------TKMPCESSPPESADTPTSTRRQPKTPLEKRDV------QKELS 1405
T T++ ++ E PTST + TPL V E S
Sbjct: 2533 STLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEAS 2592
Query: 1406 ALKKL-------------TQTSGETTHTDKVPGGEDKSINAFRETAKQKLDPAAS----- 1447
L T +S T +P ++ + P AS
Sbjct: 2593 TLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEAST 2652
Query: 1448 --------------VTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIA 1493
TG+ P T E + G + TP+ +T A
Sbjct: 2653 LSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGER---STPLTNILVSTTLLANSEA 2709
Query: 1494 CRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKA-----MHTPKPAVSGE 1548
PVDT T ++ S E ++R TPS G + + P S E
Sbjct: 2710 STLSTTPVDTSTPVTTSAEASSSPTTAEGT--SMRISTPSDGSTPLTSILVSTLPVASSE 2767
Query: 1549 KNIYA--FMGTPVQKLDLTENLTG------SKRRLQTPKEKAQALEDL-AGFKELFQTRG 1599
+ + + T + TE + + TP E + L + + +
Sbjct: 2768 ASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEA 2827
Query: 1600 HTEESMTNDKTAKVACK---SSQPDPDKN---PASSKRRLKTSLGKVGVKEELLA---VG 1650
T + D + V SS P + P S+ T L + V +A
Sbjct: 2828 GTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEAS 2887
Query: 1651 KLTQTSGETT---HTHTE-----PTGDGKSMKAFMESP-----KQILDSAASLTGSKR-- 1695
L+ T +T+ T TE T +G SM S IL S + GS+
Sbjct: 2888 TLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEAST 2947
Query: 1696 ------QLRTP----KGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQPD-L 1744
RTP S P G TP + +T+ + + +S+ L
Sbjct: 2948 LSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTL 3007
Query: 1745 VDTP--TSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKP------AVGEEKDIN 1796
TP TS+ + T E TPS G T P A+ E ++
Sbjct: 3008 SRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLS 3067
Query: 1797 T----------------FLGTPVQKLDQP------GNLPGSNRRLQTRKEKAQALEELTG 1834
T TP + P G+ P + + T + A+ L+
Sbjct: 3068 TTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLST 3127
Query: 1835 FRELFQTPCT------DNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEE 1888
TP T +PTT E T+ P S P++ T P ++ E+
Sbjct: 3128 TPVDTSTPVTTSTEAHSSPTTSEGTS------MPTSTPSEGSTPLTYMPVSTMLVVSSED 3181
Query: 1889 EFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKA 1948
L+ + S T + + + TP E + L ++P S TP +
Sbjct: 3182 STLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVS----NTPVASS 3237
Query: 1949 KALEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLGKVGV 2008
+A L TP + +T TE S P + PTS+ L
Sbjct: 3238 EA-------SILSTTPVDSNTPLTTS--TEASSSPPTAEGTSMPTSTPSEGSTPLTS--- 3285
Query: 2009 KEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKE 2068
+PV T S +T+ A + + +++ P GT M T E
Sbjct: 3286 ----MPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSS--PPIADGTSMP--TSTYSE 3337
Query: 2069 EAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKR 2128
+ L +++ F T + TT + +P S + S T +
Sbjct: 3338 GSTPLTNMS-----FSTTPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTS 3392
Query: 2129 DIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKA 2188
E + L + +T T V + +N T + T + P +G +
Sbjct: 3393 SPSEGTTPLASMPVST-TPVVSSE----VNTLSTTPVDSNTLVTTSTEASSSPTIAEGTS 3447
Query: 2189 QPLEDLA-GLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKAD 2247
P + G L P+ T + E +T S P TP + S A+
Sbjct: 3448 LPTSTTSEGSTPLSIMPLSTTPVASSEAST----LSTTPVDTSTPVTTSSPTNSSPTTAE 3503
Query: 2248 VEE--ESLALRKRTPSVGKAMDTPKPAGGDEK-------DMKAFMGTPVQKLDLPGNLPG 2298
V S A TP + T A + D F+ + Q P L
Sbjct: 3504 VTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATLQV 3563
Query: 2299 SKRWPQTPKEKAQALEDL--------AGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPV 2350
+ TP E + +L + + TP D+ T +T+ P+ +
Sbjct: 3564 TTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVI 3623
Query: 2351 DTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVS 2395
P ST L V + + + ++ +DT P ++
Sbjct: 3624 TLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVIT 3668
Score = 52.8 bits (125), Expect = 6e-06
Identities = 501/2831 (17%), Positives = 847/2831 (29%), Gaps = 352/2831 (12%)
Query: 324 ESVQTPSKAVGASFPLYEPAKMKTPVQ---------YSQQQN--SPQKHKNKDLYTTGRR 372
E+ +P+ A G S P P++ TP+ S + N S +K T
Sbjct: 1137 EASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTE 1196
Query: 373 ESVNLGKSEGFKAGDKTLTPRKLSTR------NRTPAKVEDAADSATKPENLS-----SK 421
S +E T TP + ST TP +A+ +T P + S S
Sbjct: 1197 ASSPPPTAE--VTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSA 1254
Query: 422 TRGSIPTDVE--VLPTETEIHNEPFLTLWLTQVERKIQKDSLSKPEKLGTTAGQMCSGLP 479
S PT E LPT T LT + ++ PE + + P
Sbjct: 1255 ETSSSPTTAEGTSLPTSTTSEGSTLLT------SIPVSTTLVTSPEASTLLTTPVDTKGP 1308
Query: 480 GLSSVDINNFGDSINESEGIPLKRRRVSFGGHLRPELFDENLPPNTPLKRGEA------- 532
++S N S +EG + S G R L ++P NT L A
Sbjct: 1309 VVTS---NEVSSSPTPAEGTSMPTSTYSEG---RTPL--TSIPVNTTLVASSAISILSTT 1360
Query: 533 ------PTKRKSLVMHTPPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSLVISPPAPSPR 586
P + +P + PS + I V V+S A +
Sbjct: 1361 PVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTP---VVSSEASTLS 1417
Query: 587 KTPVASDQRRRSCKTAPASSSKSQ-----TEVPKRGGRKSGNLPSKRVSISRSQHDILQM 641
TPV + + A +S + ++ T P G ++P ++ S+ L
Sbjct: 1418 ATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLST 1477
Query: 642 I-------------CSKRRSGASEANLIVAKSWADVVKLGAKQTQTKVIKHGPQRSMNKR 688
S + A ++ ++ L + T + S++
Sbjct: 1478 TPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTT 1537
Query: 689 QRRPATPKKPVGEVHSQFSTGHANSPCTIIIGKAHTEKVHVPARPYRVLN---NFISNQK 745
+TP + S +T S T + T +P V++ N +S
Sbjct: 1538 PAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTP 1597
Query: 746 MDFKEDLSGIAEMFKTPVKEQPQLTSTCHIAISNSENLLGKQFQGTDSGEEPLLPTSESF 805
+D K ++ E + E +T + S + S E L T+
Sbjct: 1598 IDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVD 1657
Query: 806 GGNVFFSAQNAAKQPSDKCSASPPLRRQCIRENGNVAKTPRNTYKMTSLETKTSDTETEP 865
+ ++ + P+ S P + T R T +S + S T +
Sbjct: 1658 SNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDN 1717
Query: 866 SKTVSTANRSGRSTEFRNIQKLPVESKSEETNTEIVECILKRGQKATLLQQRREGEMKEI 925
S V+T+ + S +P + SE T T + + + +
Sbjct: 1718 STPVTTSTEARSSPTTSEGTSMPNSTPSEGT-TPLTSIPVSTTPVLSSEASTLSATPIDT 1776
Query: 926 ERPFETYKENIELKENDEKMKAMKRSRTWGQKCAPMSDLTDLKSLPDTELMKDTARGQNL 985
P T E E + + G +T L S P + + + L
Sbjct: 1777 STPVTTSTEATSSPTTAEGTSIPTSTLSEG--------MTPLTSTPVSHTLVANSEASTL 1828
Query: 986 LQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPTHTKQQLKASLGKVGVKEELLAVGKFT 1045
T + +P ++ P + E + T T + +L + V +A
Sbjct: 1829 STTPVDSNSPVVTSTAVSSSPTPA---EGTSIATSTPSEGSTALTSIPVSTTTVA----- 1880
Query: 1046 RTSGETTHTHREPAGDGKSIRTFKESPKQILDPAARVTGMKKWPRTPKEEAQSLEDLAGF 1105
S ET PA + T+ Q+ G TP+E L +
Sbjct: 1881 --SSETNTLSTTPAVTSTPVTTYA----QVSSSPTTADGSSMPTSTPREGRPPLTSIP-- 1932
Query: 1106 KELFQTPGPSEESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLALRK 1165
S T +++I S TP +T S AD
Sbjct: 1933 -----------VSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTAD---------- 1971
Query: 1166 LTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLA 1225
G +M TP + G TP+ + L+ TL S
Sbjct: 1972 -----GTSMPTPAYSEGS---------TPLTSMPLSTTLVVSSEASTLSTTPVDT----- 2012
Query: 1226 GFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLAC 1285
TP T ++ TT S P + T P + EG L+
Sbjct: 2013 ------STPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLST 2066
Query: 1286 RNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALED 1345
+ T S + + + P + L ++ S +P+
Sbjct: 2067 TPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEAST----- 2121
Query: 1346 LTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELS 1405
L TP + V +T++ P E TST +TPL V +
Sbjct: 2122 ------LSTTPVDSNSPVIT--STEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVV 2173
Query: 1406 ALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLE 1465
A ++ S T ++ ++ + + + GS P+
Sbjct: 2174 ASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVV 2233
Query: 1466 DLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFF 1525
+ L TPV T P T T + + + PTS+ + L + V
Sbjct: 2234 -TSEASTLSATPVDTSTPVT-TSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLV 2291
Query: 1526 ALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQAL 1585
A + + + + + P + + +P + T T + TP +
Sbjct: 2292 ANSEVSTLSTTPVDSNTPFTTSTE-----ASSPPPTAEGTSMPTSTSSEGNTPLTRMPVS 2346
Query: 1586 EDL-AGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKE 1644
+ A F+ + + S ++ + D P S+ T L V V
Sbjct: 2347 TTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVST 2406
Query: 1645 ELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGKS 1704
+ + + S T T T ++ + + + ++ G+ P +
Sbjct: 2407 MPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTT 2466
Query: 1705 EVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQPDLV------------------D 1746
V AG L TP T MT S ++ +V
Sbjct: 2467 PVVSSEAG--TLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVST 2524
Query: 1747 TPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKL 1806
TP +S S D+ + + + SA A T P + TP++
Sbjct: 2525 TPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEG-----STPLR-- 2577
Query: 1807 DQPGNLPGSNRRLQTRKEKAQALEEL-TGFRELFQTPCTDNPTTDEKTTKKILCKSPQSD 1865
++P S + L + + + + T T + +PTT + T+ P S
Sbjct: 2578 ----SMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTS------MPIST 2627
Query: 1866 PADTPTNTKQRPKRSLKKADVEEEFLAFRKL--------------TPSAGKAMHTPKAAV 1911
P++ T+ ++ A E L+ + +P+ + P +
Sbjct: 2628 PSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTP 2687
Query: 1912 GEEKD--INTFVGTPV---EKLDLLGNLPGSKRRPQTPKEKAKALEDLA-GFKELFQTPG 1965
GE N V T + + L P P T +A + A G TP
Sbjct: 2688 GERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPS 2747
Query: 1966 HTEESMTDDKITEVSCKSPQPDPVKT---PTSSKQRLKISLGKVGVKEEV--LPVGKLTQ 2020
+T ++ + S + V T TS EV +P ++
Sbjct: 2748 DGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSE 2807
Query: 2021 TSGK-TTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRT------PKEEAQSL 2073
TS T+ T + P T P T P A
Sbjct: 2808 TSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEG 2867
Query: 2074 EDLAGFKELFQTPDHTEESTTDDKT-----------TKIACKSPPPESMDTPTSTRRRPK 2122
L + TP + E++T T T+ + E P ST
Sbjct: 2868 STLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVS 2927
Query: 2123 TPLGKRDIV------EELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTG 2176
TPL + E S L T T E T + S G
Sbjct: 2928 TPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASS----SPTTAEGTSMPISTPG 2983
Query: 2177 SKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFK 2236
+R P T + + L +TP T P T +T+ + + G P
Sbjct: 2984 ERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVT--TSTEASSSPTTAEGTGIPISTP 3041
Query: 2237 PQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNL 2296
+ L V +A+ + + +D+ P + + TP + +P +
Sbjct: 3042 SEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSS--PTPAEGTSMPIST 3099
Query: 2297 PGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPAST 2356
P T + + L TP D T +T+ + P ST
Sbjct: 3100 YSEGSTPLTGVPVSTTPVTSSAISTLSTTP-VDTSTPVTTSTEAHSSPTTSEGTSMPTST 3158
Query: 2357 KQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKP-AVSDEKNINTFVE-------TPV 2408
L V + + + + +DT P S E +T E TP
Sbjct: 3159 PSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPS 3218
Query: 2409 QKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQ 2468
+ + L ++P S TP +EA L TP + +T TE S P
Sbjct: 3219 EGMTPLTSVPVS----NTPVASSEA-------SILSTTPVDSNTPLTTS--TEASSSPPT 3265
Query: 2469 PESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKE- 2527
E S+ PL + VS T S ET+ T P S + + +
Sbjct: 3266 AEGTSMPTSTPSEGSTPLTS-------MPVSTTTVASSETSTLSTTPADTSTPVTTYSQA 3318
Query: 2528 -SPKQILDPAASVTGSRRQLRT-------------RKEKARALEDLVDFKELFSAPGHTE 2573
S I D + T + + T E + VD +
Sbjct: 3319 SSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTSTEAS 3378
Query: 2574 ESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTH 2633
S T + T IP SP T A+ T P V E++ + S T
Sbjct: 3379 LSPTTAEGTSIPTSSPSEGTTPLASMP---VSTTP--VVSSEVNTLSTTPVDSNTLVTTS 3433
Query: 2634 KEPASGD---EGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSG 2690
E +S EG + + P+ P P A E + LS T
Sbjct: 3434 TEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEA----------STLSTTPV 3483
Query: 2691 HTQESLTAGKATKIPCESPP--LEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGE 2748
T +T T P S P EV ST T + + V P A S E
Sbjct: 3484 DTSTPVT----TSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVA------SSE 3533
Query: 2749 TTDADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDL---AGFKD 2805
+ P + + S+ Q + A++ + R P E + ++ + + +
Sbjct: 3534 ASTLSTTPVDSNTFV----TSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVT 3589
Query: 2806 PAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTS 2865
+ T + + D++T + + T P + +V ++ V + T
Sbjct: 3590 SSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTI 3649
Query: 2866 GETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDL-ASFQEL 2924
E PV Q + + E G+ P E + PL + S +
Sbjct: 3650 SEAGTASTLPVDTSTPVITSTQVSSSPVTPE---GTTMPIWTPSEGSTPLTTMPVSTTRV 3706
Query: 2925 SQTPGHTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAP-KVEPVGD--VVSTRDPV 2981
+ + G T + + + + S L + + P ++ +G +VST
Sbjct: 3707 TSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLGTTILVSTTPVT 3766
Query: 2982 KSQSKSNTSLP 2992
+ S S+P
Sbjct: 3767 RFPESSTPSIP 3777
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 75.5 bits (184), Expect = 8e-13
Identities = 125/597 (20%), Positives = 243/597 (40%), Gaps = 54/597 (9%)
Query: 1306 EKDIIIFVGTPVQKLDLTENLTGSKRRP----QTPKEEAQALEDLTGFKELFQTPGHTEE 1361
EK+ +I V ++ +TE +T + + + +EE E+ G +E ++P EE
Sbjct: 451 EKETVI-VEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPP-AEE 508
Query: 1362 AVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTD 1421
A + K K P + A+ + + + K+P E + +K S K+ ++ E
Sbjct: 509 AASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEA---- 564
Query: 1422 KVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTD 1481
K P E+ A ++ ++ PA S K+ EKA+ + +KE ++P
Sbjct: 565 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAK-----SPVKEEAKSPAEAK 619
Query: 1482 KPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTP 1541
P E + +S P+ +PT + +S + + EE + ++P +A +P
Sbjct: 620 SPVKEEAKSPAEVKS-PEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEA-KSP 677
Query: 1542 KPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTP-KEKAQALEDLAGFKELFQTRGH 1600
+ A S K A +P + + S + ++P KE+A++ E + +
Sbjct: 678 EKAKSPVK---AEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPE---------KAKSP 725
Query: 1601 TEESMTNDKTAKVACKSSQPDPDKNPASSKRR---LKTSLGKVGVKEELLA-VGKLTQTS 1656
+E + AK K P+K + K + +K+ K KEE + K + +
Sbjct: 726 VKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKA 785
Query: 1657 GETTHTHTEPTGDGKS-MKAFMESPKQILDSAASLTGSKRQLRTPKG-KSEVPEDLAGFI 1714
+ KS +K ++P++ + + ++ P+ K + P A
Sbjct: 786 KSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEE 845
Query: 1715 ELFQTPSHTKESMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQ 1774
+ TP T+E ++K A +P + + + +PK S K + ++E +K+
Sbjct: 846 KAPATPK-TEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKES--KVEAKKEEAEDKKK 902
Query: 1775 TPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRK--EKAQALEEL 1832
P+ K PA E K+ P +K + P + + K EK +A E
Sbjct: 903 VPTPEK----EAPAKVEVKED----AKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEK 954
Query: 1833 TGFRELFQTPCTDNPTTDEKTTK--KILCK---SPQSDPADTPTNTKQRPKRSLKKA 1884
+E + P T+ K + K L K P+++ A+ ++T Q+ + +KA
Sbjct: 955 KDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKA 1011
Score = 74.7 bits (182), Expect = 1e-12
Identities = 119/635 (18%), Positives = 229/635 (36%), Gaps = 68/635 (10%)
Query: 2617 SAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKK-------------PNPVEEEPSR 2663
S E L + STH +E IKV+++ K+ EEE
Sbjct: 421 SLPEGLPKIPSVSTHIK---VKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKE 477
Query: 2664 RRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRH 2723
+ KE+ E+ A E S +E+ + K K P + + + K
Sbjct: 478 AKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEE 537
Query: 2724 LRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGS 2783
++ +VK A + ++ K P E+ A +S ++ +PA S
Sbjct: 538 AKS---PAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKS 594
Query: 2784 RRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPR 2843
++P ++ +++ A A +E K P K+ ++ A S ++
Sbjct: 595 PAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKS 654
Query: 2844 TRAQKVEVKEELLAVGKLTQTSGETTHTDKEPV-GEGKGTKAFKQPAKRKLDAEDVIGS- 2901
++ + E+ + K S E K PV E K + K P K + + + S
Sbjct: 655 PEKEEAKSPEKAKSPVKAEAKSPEKA---KSPVKAEAKSPEKAKSPVKEEAKSPEKAKSP 711
Query: 2902 -RRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKPLKISR 2960
+ + ++P++ P+++ A E +++P E + A S P+ K L +
Sbjct: 712 VKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKS--------PEKAKTLDVKS 763
Query: 2961 RVLRAPKVEPVGDVV-----STRDPVKSQSKS-NTSLPPLPFKRGGGKDGSVTGTKRLRC 3014
+ P E + PVK + KS + PL K+ + K +
Sbjct: 764 PEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPL-------KEDAKAPEKEI-- 814
Query: 3015 MPAPEEI-----VEELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEPAEELNSND 3069
P EE+ EE P K + P+ + P + +T K+ EE +
Sbjct: 815 -PKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPA-----TPKTEEKKDSKKEEAPKKE 868
Query: 3070 MKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKKPMKTSP 3129
K E K + +V + K + ++++ + ++ T ++E+ + K KT
Sbjct: 869 APKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKT-- 926
Query: 3130 EMDIQNPDDG----ARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKVLMQN 3185
E+ + PDD KP + + K+ + + + + E + + +
Sbjct: 927 EVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEP 986
Query: 3186 QKGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQ 3220
K K E S + + S+P E K+ +
Sbjct: 987 SKPKAEKAEKSS---STDQKDSKPPEKATEDKAAK 1018
Score = 72.0 bits (175), Expect = 9e-12
Identities = 122/590 (20%), Positives = 225/590 (38%), Gaps = 68/590 (11%)
Query: 2067 KEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLG 2126
+EE E+ G +E ++P EE+ + +K K K + + + K+P
Sbjct: 485 EEEGGEEEEAEGGEEETKSPP-AEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAE 543
Query: 2127 KRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKG 2186
+ + S K+ ++ K P E+ ++ + P + + +K + ++P
Sbjct: 544 VKSPEKAKSPAKEEAKSPPEAKSPEKEE------AKSPAEVKSPEKAKSPAKEEAKSPAE 597
Query: 2187 KAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKA 2246
P + + +KE ++P P E + +S P+ +PT + +S +
Sbjct: 598 AKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKS--PEKAKSPTKEEAKSPEKAKSP 655
Query: 2247 DVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTP 2306
+ EE + ++P +A K + +KA +P +K P K ++P
Sbjct: 656 EKEEAKSPEKAKSPVKAEAKSPEKA----KSPVKAEAKSP-EKAKSP-----VKEEAKSP 705
Query: 2307 KEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPK-RNLR 2365
++ +++ A E ++P ++ T EK KSP + +P K K + L
Sbjct: 706 EKAKSPVKEEAKSPEKAKSPVKEEAKTPEK-----AKSPVKEEAKSPEKAKSPEKAKTLD 760
Query: 2366 KADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQ 2425
E + A + A K + K V +E ++P+
Sbjct: 761 VKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPL----------------- 803
Query: 2426 TPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCK--------SPQPESFKTSRS 2477
KE A+A E + KE ++P EE + K+ E K +P+ E K S+
Sbjct: 804 --KEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKK 861
Query: 2478 SK-QRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKA-FKESPKQI-LD 2534
+ + + P KV+ K+EP AV K + E + E D K + KE+P ++ +
Sbjct: 862 EEAPKKEAPKPKVEEKKEP-AVEKPKESKVEAKKEEAE---DKKKVPTPEKEAPAKVEVK 917
Query: 2535 PAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELT 2594
A + + A+A E S P +E+ K+TK P E
Sbjct: 918 EDAKPKEKTEVAKKEPDDAKAKEP--------SKPAEKKEAAPEKKDTKEEKAKKPEEKP 969
Query: 2595 DTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIK 2644
T K KT ++ K + E+ + T Q E A+ D+ K
Sbjct: 970 KTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTD-QKDSKPPEKATEDKAAK 1018
Score = 61.6 bits (148), Expect = 1e-08
Identities = 130/651 (19%), Positives = 241/651 (37%), Gaps = 84/651 (12%)
Query: 884 IQKLPVESKSEETNTEIVECILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDE 943
+ K+P S + +E ++++ +K T++ + + E + E E ++ + +E E
Sbjct: 426 LPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKE 485
Query: 944 KMKAMKRSRTWGQKCAPMSDLTDLKSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKIT 1003
+ + G++ + KS P E + AK+P E+ K +
Sbjct: 486 EEGGEEEEAEGGEE--------ETKSPPAEEAASP----------EKEAKSPVKEEAK-S 526
Query: 1004 KMPCQSLQPEPINTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETTHTHREPAGDGK 1063
+S + E +P K KA K KEE + + E + E K
Sbjct: 527 PAEAKSPEKEEAKSPAEVKSPEKA---KSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEK 583
Query: 1064 SIRTFKE---SPKQILDPAARVTGMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMT 1120
+ KE SP + P + +K+ ++P E +++ A ++P ++
Sbjct: 584 AKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTK 643
Query: 1121 DEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPA 1180
+E + KSP E +P K K + + + + +P K+ + + A
Sbjct: 644 EEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPV-KEEA 702
Query: 1181 GGDEKDIKAFMGTPVQKLDLAGTLPGS--KRQLQTPKEKAQALEDLAGFKELFQTPGHTE 1238
EK +PV++ + S K + +TP++ +++ A E ++P +
Sbjct: 703 KSPEK-----AKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAK 757
Query: 1239 ELVAAGKTTKIPCDSPQSDPVDT-PTSTKQRPKRSIR-----KADVEGELLACRNLMPSA 1292
L K P P D P K K ++ K+ ++ + A +P
Sbjct: 758 TLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIP-- 815
Query: 1293 GKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDLTGFKEL 1352
K P EEK + V P +K + ++ P TPK
Sbjct: 816 -KKEEVKSPVKEEEKPQEVKVKEPPKKAE-------EEKAPATPK--------------- 852
Query: 1353 FQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSALKKLTQ 1412
TEE + K E+ P+ + +PK K + +KE + KK
Sbjct: 853 ------TEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKE--SKVEAKKEEAEDKKKVP 904
Query: 1413 TSGETTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGLKE 1472
T E KV ED E AK++ D A + SK P K++A P E +E
Sbjct: 905 TP-EKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSK--PAEKKEAAP-EKKDTKEE 960
Query: 1473 LFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEE 1523
+ P +KP T K + D + SKP+++++ + +++
Sbjct: 961 KAKKP--EEKPKTEAKA------KEDDKTLSKEPSKPKAEKAEKSSSTDQK 1003
Score = 60.5 bits (145), Expect = 3e-08
Identities = 118/557 (21%), Positives = 214/557 (38%), Gaps = 64/557 (11%)
Query: 1822 RKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSL 1881
++E+ EE G E ++P + + EK K SP + A +P K K
Sbjct: 484 KEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAK-----SPVKEEAKSPAEAKSPEKEEA 538
Query: 1882 KK-ADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRR 1940
K A+V+ A +P+ +A P+A E+++ + P E +K
Sbjct: 539 KSPAEVKSPEKA---KSPAKEEAKSPPEAKSPEKEEAKS----PAEVKSPEKAKSPAKEE 591
Query: 1941 PQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLK 2000
++P E + + KE ++P + + ++ + KSP+ K+PT + +
Sbjct: 592 AKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEK--AKSPTKEEAKSP 649
Query: 2001 ISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKS-IKAFKESAKQMLDPANYGTGM 2059
K KEE K + + + ++ KS +KA +S ++ P
Sbjct: 650 -EKAKSPEKEEA----KSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKS 704
Query: 2060 ERWPRTP-KEEAQSLEDLAG-FKELFQTPDHTEESTTDDKTTKIACKSPPP------ESM 2111
++P KEEA+S E KE +TP+ + ++ + KSP +S
Sbjct: 705 PEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSP 764
Query: 2112 DTPTSTRRRPKTPL------GKRDIVEELSALKQLTQTTHTD------KVPGDEDKGINV 2159
+ T + ++P K + EE+ + ++ D ++P E+ V
Sbjct: 765 EAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPV 824
Query: 2160 FRETAKQ--KLDPAASVTGSKRQPRTPKG--KAQPLEDLAGLKELFQTPICTDKPTTHEK 2215
E Q K+ ++ P TPK K ++ A KE + + K EK
Sbjct: 825 KEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEK 884
Query: 2216 TTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEE-----ESLALRKRTPSVGKAMDTPK 2270
+ + + + + P+ K + K +V+E E + K+ P KA + K
Sbjct: 885 PKESKVEAKKEEAEDKKKVPTPE-KEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSK 943
Query: 2271 PAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDK 2330
PA E + T +K +K+ + PK +A+A ED K L + P K
Sbjct: 944 PAEKKEAAPEK-KDTKEEK---------AKKPEEKPKTEAKAKED---DKTLSKEPSKPK 990
Query: 2331 PTTDEKTTKIACKSPQP 2347
EK++ K +P
Sbjct: 991 AEKAEKSSSTDQKDSKP 1007
Score = 60.1 bits (144), Expect = 4e-08
Identities = 126/615 (20%), Positives = 226/615 (36%), Gaps = 71/615 (11%)
Query: 2441 KELFQTPGHTEESMTDDKITEVSCKSPQPESFKT--------SRSSKQRLKIPLVKVDMK 2492
KE TEE+ +++TE K + E K + ++ K P +
Sbjct: 452 KETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAAS 511
Query: 2493 EEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRT-RKE 2551
E A S + + + + ++KS K SP++ PA S + ++ KE
Sbjct: 512 PEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVK-SPEKAKSPAKEEAKSPPEAKSPEKE 570
Query: 2552 KARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKE 2611
+A++ + V E +P E K P ++ PE + + +
Sbjct: 571 EAKSPAE-VKSPEKAKSPAKEE--------AKSPAEAKSPEKAKSPVKEEAKSPAEAKSP 621
Query: 2612 VKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAK---KKPNPVEEE-------- 2660
VKEE + + + T +E S ++ K+ AK K +PV+ E
Sbjct: 622 VKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAK 681
Query: 2661 -PSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTAS 2719
P + ++P++ P+++ A E ++ S +E+ + KA +SP E T
Sbjct: 682 SPVKAEAKSPEKAKSPVKEEAKSPEKAK-SPVKEEAKSPEKA-----KSPVKEEAKTPEK 735
Query: 2720 TKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAAS 2779
K ++ + + + P K T + K PA E+ A K K +P
Sbjct: 736 AKSPVKEEAKSPEKAKSPEKAK---TLDVKSPEAKTPAKEEARSPADKFPEK-AKSPVKE 791
Query: 2780 VTGSRRRPRAP-RESAQAIE-DLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATS 2837
S + ++P +E A+A E ++ ++ + EE + K P K + E + AT
Sbjct: 792 EVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPAT- 850
Query: 2838 SKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDA-- 2895
P+T +K KEE +P E K A ++P + K++A
Sbjct: 851 ----PKTEEKKDSKKEE------------APKKEAPKPKVEEKKEPAVEKPKESKVEAKK 894
Query: 2896 EDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKP 2955
E+ ++ P KE +E + P E+A D + P K
Sbjct: 895 EEAEDKKKVPTPEKEAPAKVE-----VKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKE 949
Query: 2956 LKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDGSVTGTKRLRCM 3015
++ + K + + T K K+ + P P K + S T K +
Sbjct: 950 AAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKP-KAEKAEKSSSTDQKDSK-- 1006
Query: 3016 PAPEEIVEELPASKK 3030
PE+ E+ A K
Sbjct: 1007 -PPEKATEDKAAKGK 1020
Score = 59.3 bits (142), Expect = 6e-08
Identities = 126/614 (20%), Positives = 226/614 (36%), Gaps = 74/614 (12%)
Query: 543 TPPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSLVISPP---APSPR---KTPVASDQRR 596
T V ++ KE + GK+E G E + SPP A SP K+PV + +
Sbjct: 467 TEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKS 526
Query: 597 -RSCKTAPASSSKSQTEVPKRGGRKSGNLPSKRVSISRSQHDILQMICSKRRSGASEANL 655
K+ +KS EV KS P+K + S + ++ S A +
Sbjct: 527 PAEAKSPEKEEAKSPAEVKSPEKAKS---PAKEEAKSPPEAK-----SPEKEEAKSPAEV 578
Query: 656 IVAKSWADVVKLGAKQTQTKVIKHGPQRSMNKRQRRPATPKKPVGEVHSQFSTGHANSPC 715
+ K AK + + + + PA K PV E A SP
Sbjct: 579 KSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKE--------EAKSPA 630
Query: 716 TIIIGKAHTEKVHVPARPYRVLNNFISNQKMDFKEDLSGIAEMFKTPVKEQPQLTSTCHI 775
+ EK P + K KE+ E K+PVK + +
Sbjct: 631 EV----KSPEKAKSPTKEEA---KSPEKAKSPEKEEAKS-PEKAKSPVKAEAK------- 675
Query: 776 AISNSENLLGKQFQGTDSGEEPLLPTSESFGGNVFFSAQNAAKQPSDKCSASPPLRRQCI 835
+ +++ + + + + + P+ ++S AK P + + SP + +
Sbjct: 676 SPEKAKSPVKAEAKSPEKAKSPVKEEAKS---------PEKAKSPVKEEAKSPEKAKSPV 726
Query: 836 RENGNVAKTPRNTYKMTSLETKTSDTETEPSKTVSTANRSGRS-TEFRNIQKLPVESKSE 894
+E AKTP E K+ + P K + +S + T + + P + E
Sbjct: 727 KEE---AKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPE 783
Query: 895 ETNTEIVECILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDEKMKAMKRSRTW 954
+ + + E + + + L++ + KEI + E K ++ +E +++K + +
Sbjct: 784 KAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKK-EEVKSPVKEEEKPQEVKVKEPPKKA 842
Query: 955 GQKCAPMSDLTDLKSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKITKMPCQSLQPE- 1013
++ AP + T+ K E + + + + K P EK K +K+ + + E
Sbjct: 843 EEEKAPATPKTEEKKDSKKE---EAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAED 899
Query: 1014 PINTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETTHTHREPAGDGKSIRTFKESPK 1073
PT K+ + KV VKE+ E T ++ D K+ K + K
Sbjct: 900 KKKVPTPEKE----APAKVEVKED--------AKPKEKTEVAKKEPDDAKAKEPSKPAEK 947
Query: 1074 QILDPAARVT---GMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACK 1130
+ P + T KK PK EA++ ED K L + P + ++ ++
Sbjct: 948 KEAAPEKKDTKEEKAKKPEEKPKTEAKAKED---DKTLSKEPSKPKAEKAEKSSSTDQKD 1004
Query: 1131 SPPPESVDTPTSTK 1144
S PPE + K
Sbjct: 1005 SKPPEKATEDKAAK 1018
Score = 45.4 bits (106), Expect = 9e-04
Identities = 142/694 (20%), Positives = 256/694 (36%), Gaps = 110/694 (15%)
Query: 189 GRNGRNAADPISGDFKE-ISSVKLVSRYGELKSVPTTQCLDNSKKNESPFWKLYESVKKE 247
G R PI E + + VS + ++KS + ++ S+K + E +
Sbjct: 408 GEECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVT 467
Query: 248 LDVKSQKENVLQYCRKSGLQTDYATEKESADGLQGETQL-----LVSRKSRPKSGGSGHA 302
+V ++E + ++ + + E+E A+G + ET+ S + KS A
Sbjct: 468 EEVTEEEE---KEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEA 524
Query: 303 V--AEPASPEQELDQNKGKGRDVESVQTPSKAVGASFPLYEPAKMKTPVQYSQQQNSPQK 360
AE SPE+E ++ + + E ++P+K S P + K+P + ++ SP +
Sbjct: 525 KSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKS-----PPEAKSPEK--EEAKSPAE 577
Query: 361 HKNKDLYTTGRRESVNLGKSEGFKAGDKTLTPRKLSTRNRTPAKVEDAADSATKPENLSS 420
K+ + + +E K+ +K +P K ++ AK + A P + S
Sbjct: 578 VKSPEKAKSPAKEEAK--SPAEAKSPEKAKSPVKEEAKSPAEAK-SPVKEEAKSPAEVKS 634
Query: 421 KTRGSIPTDVEVLPTETEIHNEPFLTLWLTQVERKIQKDSLSKPEKLGTTAGQMCSGLPG 480
+ PT E E + +K+ PEK + P
Sbjct: 635 PEKAKSPTKEEAKSPEK---------------AKSPEKEEAKSPEKAKSPVKAEAKS-PE 678
Query: 481 LSSVDINNFGDSINESEGIPLKRRRVSFGGHLRPELFDENLPPNTPLK-RGEAPTKRKSL 539
+ + S +++ P+K S PE +P+K ++P K KS
Sbjct: 679 KAKSPVKAEAKSPEKAKS-PVKEEAKS------PE------KAKSPVKEEAKSPEKAKSP 725
Query: 540 VMH---TPPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSLVISPPAPSPRKTPVASDQRR 596
V TP K +KE+ + K +S KA++L + P KTP + R
Sbjct: 726 VKEEAKTPEKAKSPVKEEAKSPEKAKSPE------KAKTLDVKSP---EAKTPAKEEAR- 775
Query: 597 RSCKTAPASSSKSQTEVPKRGGRKSGNLPSKRVSISRSQHDILQMICSKRRSGASEANLI 656
+PA + + P + KS P K S K + A E +
Sbjct: 776 -----SPADKFPEKAKSPVKEEVKS---PEKAKS------------PLKEDAKAPEKEIP 815
Query: 657 VAKSWADVVKLGAKQTQTKVIKHGPQRSMNKRQRRPATPKKPVGEVHSQFSTGHANSPCT 716
+ VK K + KV K P+++ + ++ PATPK + + +P
Sbjct: 816 KKEEVKSPVKEEEKPQEVKV-KEPPKKA--EEEKAPATPKTEEKKDSKKEEAPKKEAP-- 870
Query: 717 IIIGKAHTEKVHVPA--RPYRVLNNFISNQKMDFKEDLSGIAEMFKTPVKEQPQLTSTCH 774
K E+ PA +P K++ K++ + + TP KE P
Sbjct: 871 ----KPKVEEKKEPAVEKP--------KESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKE 918
Query: 775 IAISNSENLLGKQFQGTDSGEEPLLPTSESFGG-NVFFSAQNAAKQPSDKCSASPPLRRQ 833
A + + K+ +EP P + + + AK+P +K P +
Sbjct: 919 DAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEK----PKTEAK 974
Query: 834 CIRENGNVAKTPRNTYKMTSLETKTSDTETEPSK 867
++ ++K P K E K+S T+ + SK
Sbjct: 975 AKEDDKTLSKEPSKP-KAEKAE-KSSSTDQKDSK 1006
Score = 40.4 bits (93), Expect = 0.029
Identities = 67/377 (17%), Positives = 136/377 (36%), Gaps = 25/377 (6%)
Query: 106 RKSTEFPRKIREQEPARRVSRSSFSSDPDEKAQDSKAYSKITEGKVSGNPQVHIKN---- 161
++ + P +++ E A+ ++ S + K+ + E K + +K
Sbjct: 569 KEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKS 628
Query: 162 ---VKEDSTADDSKDSVAQGTTNVHSSE-HAGRNGRNAADPISGDFKEI----SSVKLVS 213
VK A A+ S E ++ A P+ + K S VK +
Sbjct: 629 PAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEA 688
Query: 214 RYGELKSVPTTQCLDNSKKNESPFWKLYES-------VKKELDVKSQKENVLQYCRKSGL 266
+ E P + + +K +SP + +S VK+E + ++ ++ KS
Sbjct: 689 KSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPE 748
Query: 267 QTDYATEKESADGLQGETQLLVSRKSRPKSGGSGHAVAEPASPEQELDQNKGKGRDVESV 326
+ + ++ D E + ++R + P E + + K K E
Sbjct: 749 KAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPE-KAKSPLKEDA 807
Query: 327 QTPSKAVGASFPLYEPAKMKTPVQYSQQQNSPQKHKNKDLYTTGRRESVNLGKSEGFKAG 386
+ P K + + P K + Q + + P+K + + T + E K E
Sbjct: 808 KAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKE---EA 864
Query: 387 DKTLTPRKLSTRNRTPAKVEDAADSATKPENLSSKTRGSIPTDVEVLPTETEIHNEPFLT 446
K P+ + PA VE +S + + ++ + +PT + P + E+ E
Sbjct: 865 PKKEAPKPKVEEKKEPA-VEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEV-KEDAKP 922
Query: 447 LWLTQVERKIQKDSLSK 463
T+V +K D+ +K
Sbjct: 923 KEKTEVAKKEPDDAKAK 939
Score = 39.7 bits (91), Expect = 0.049
Identities = 130/682 (19%), Positives = 236/682 (34%), Gaps = 108/682 (15%)
Query: 2610 KEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAP 2669
+EV+E AV RL GQ E E I ++QR + EE + R A
Sbjct: 148 REVREMRGAVLRLGAARGQ---LRLEQEHLLEDIAHVRQRLDDEARQREEAEAAARALAR 204
Query: 2670 ------------KEKAQPLEDLAGFT------ELSETSGHTQESLTAGKATKIPCESPPL 2711
++KAQ L++ G+ E+ E G Q S A +
Sbjct: 205 FAQEAEAARVDLQKKAQALQEECGYLRRHHQEEVGELLGQIQGSGAAQAQMQ-------- 256
Query: 2712 EVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAK 2771
+T + K + + +++++ + E AV+ T S E + E A K +
Sbjct: 257 --AETRDALKCDVTSALREIRAQLEGHAVQSTLQSEEWFRVRLDRLSE-----AAKVNTD 309
Query: 2772 QTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPC--KSSP 2829
+ +T RR+ +A +A++ + E+ D + +
Sbjct: 310 AMRSAQEEITEYRRQLQARTTELEALKSTKDSLERQRSELEDRHQADIASYQEAIQQLDA 369
Query: 2830 ELEDTATSSKRRPRTRAQKVEVKE----ELLAVGKLTQTSGETTHTDKEPVG----EG-- 2879
EL +T + R + VK E+ A KL + GE P+ EG
Sbjct: 370 ELRNTKWEMAAQLREYQDLLNVKMALDIEIAAYRKLLE--GEECRIGFGPIPFSLPEGLP 427
Query: 2880 -----------KGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTP 2928
K + K K + + V + + +E + E A +E +
Sbjct: 428 KIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEE 487
Query: 2929 GHTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSN 2988
G EE A G + S P + ++ P K ++ +P E + P K ++KS
Sbjct: 488 GGEEEEAEGGEEETKSPPAE--EAASPEKEAK----SPVKEEAKSPAEAKSPEKEEAKSP 541
Query: 2989 TSLPPLPFKRGGGKDGSVTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIM 3048
+ +PE+ + PA ++ + P A+ E
Sbjct: 542 AEVK------------------------SPEKA--KSPAKEEAKSPPEAKSPEKEEAK-S 574
Query: 3049 KRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEV 3108
+++ K PA+E + + E K + V E ++ K EA+
Sbjct: 575 PAEVKSPEKAKSPAKEEAKSPAEAKSPE-KAKSPVKEEAKSPAEAKSPVKEEAKSPAEVK 633
Query: 3109 FVLAERIEINRNEKKPMKT-SPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQP 3167
+ K P K SPE + + A+ P+ + + K + P
Sbjct: 634 SPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEK----------AKSP 683
Query: 3168 KVAEESGGQKSAKVLMQNQKGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVTRSVK 3227
AE +K+ + + K +A + +S + P E+K+ ++ VK
Sbjct: 684 VKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKE--EAKTPEKAKSPVK 741
Query: 3228 RCAENPKKAEDNVCVKKIRTRS 3249
A++P+KA+ K + +S
Sbjct: 742 EEAKSPEKAKSPEKAKTLDVKS 763
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 75.5 bits (184), Expect = 8e-13
Identities = 328/1587 (20%), Positives = 532/1587 (33%), Gaps = 271/1587 (17%)
Query: 1723 TKESMTNEKTTKVSYRASQPDLVDTPTSSKPQ-PKRSLRKADTEEEFLAFRKQTPSA--- 1778
T +S+++++ K+ SQP P Q P+ K + + A R QT A
Sbjct: 235 TPKSISSQQPEKIK---SQPPGTGKPIQGPTQTPQTDHAKLPLQRD--ASRPQTKQADIV 289
Query: 1779 -GKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRE 1837
G+++ P+ + G P P PG + + LT +
Sbjct: 290 RGESVKPSLPSPSKPPIQQPTPGKP------PAQQPGHEKSQPGPAKPPAQPSGLT--KP 341
Query: 1838 LFQTPCTDNPTTDEKTTKKILCK--SPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRK 1895
L Q P T P T K + P PA + K ++ KA +
Sbjct: 342 LAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP------- 394
Query: 1896 LTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLG-----NLPGSKRRPQTPKEKAKA 1950
P GK TP G K VGTP G PG + P K
Sbjct: 395 --PGVGK---TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449
Query: 1951 LEDLAGFKELFQTPGHTEESMTDDKITEVSCKSP------QPDPVKTPTSSKQRLKISLG 2004
AG PG T T P QP P K P K
Sbjct: 450 PAQQAG-------PGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502
Query: 2005 KVGVK----EEVLPVGKLTQTSGKTTQTHRETAGDGKSIKA---FKESAKQMLDPANY-G 2056
+ G ++ P Q G T ++ S + K SA+Q P + G
Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG 562
Query: 2057 TGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDD--KTTKIACKSPPPESMDTP 2114
+G P T A+ Q P T TT++ P + +T
Sbjct: 563 SGKPLQPPTVSPSAK------------QPPSQGLPKTICPLCNTTELLLHVPEKANFNTC 610
Query: 2115 TSTRRRPKTPLGKR------DIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKL 2168
T + + G ++ E L Q+ + D P + +TA
Sbjct: 611 TECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKL--KTAPVTT 668
Query: 2169 DPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDP 2228
A S + + Q +PK A P +DL+ E + P +PT H + A + P+ D
Sbjct: 669 TSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADS 728
Query: 2229 VGTPTIFKPQSKRSLR-KADVEEES----LALRKRTPSVGKAMDTPKP--AGGDEKDMKA 2281
+ P K S S + KA V ++ ++ T V + T KP +
Sbjct: 729 LSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAE 788
Query: 2282 FMGTPVQKLDLPGNLPGSKRWPQTPKE----KAQALEDLAGFKELFQTPGTDKPTTDEKT 2337
TP K D + S+ +P T ++ ++A+ A ++ PG P+++ K
Sbjct: 789 EKTTPPLKTD---SAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPG---PSSESKG 842
Query: 2338 TKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRT-------PSAGKAMDTP 2390
K Q DPV K+ PK+ K + + + K + P+AG+ + TP
Sbjct: 843 QK------QVDPV----QKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTP 892
Query: 2391 KPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHT 2450
+ + ++ F L+L K QP TP+E L GF G +
Sbjct: 893 QQSPKPQEQSRRF------SLNLGSITDAPKSQPTTPQETVTG--KLFGF-------GAS 937
Query: 2451 EESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQ 2510
S + I+ P +S + MK+ P A S+ + G
Sbjct: 938 IFSQASNLISTAGQPGPHSQSGPGA--------------PMKQAP-APSQPPTSQGPPKS 982
Query: 2511 THTEPTGDSKSIKAFKES---PKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFS 2567
T P +KSI KE+ + L+P A + ++ T K+ + D K L +
Sbjct: 983 TGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP----PPIKDSKSLTA 1038
Query: 2568 APGHTEESMTIDKNTK-------------IPCKSPPPELTDTATSTKRC-----PKTRPR 2609
P ++K+ K I K PP T T + C T
Sbjct: 1039 EPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHL 1098
Query: 2610 KEVKEELSA-VERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRA 2668
E++E L + SGQ K P + K P PV E S ++
Sbjct: 1099 TEIQEWLCLNCQTQRAISGQLGDIRKMPPA--------PSGPKASPMPVPTESSSQKTAV 1150
Query: 2669 PKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRV 2728
P P L E + + L K T + PP+ D + + +
Sbjct: 1151 P-----PQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKA 1205
Query: 2729 QKVQVKEE--------PSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAP---- 2776
+Q K+ P K + +K+P EDK K L E+ P
Sbjct: 1206 SALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDK--KLLPEAKTSAPEEQKHD 1263
Query: 2777 --------AASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSS 2828
A R P+ +E Q + G P+ DDKTTK K
Sbjct: 1264 LLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGL--PSGTPQSLPKEDDKTTK-TIKEQ 1320
Query: 2829 PELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQP 2888
P+ TA + P +K E +++ Q +D +G + + P
Sbjct: 1321 PQPPCTAKPDQVEP--GKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIP 1378
Query: 2889 AKRKLDAEDVI-GSRRQPRAPKEKAQPLEDLASFQE--LSQTPGHTEELANGAADSFTS- 2944
+ D +D++ G ++ + + DLA + LS LA+ ++ T
Sbjct: 1379 SLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQP 1438
Query: 2945 ---APKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGG 3001
+P+Q D K +S E + +S + +SQ + + FK+
Sbjct: 1439 HEVSPEQPKDQEKTQSLS---------ETLEITISEEEIKESQEERKDT-----FKKDSQ 1484
Query: 3002 KDGSVTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEP 3061
+D + +K + E V+++ ++++ SE + +R RTS
Sbjct: 1485 QD--IPSSKDHK---EKSEFVDDI-TTRREPYDSVEESSESENSPVPQRKRRTSVG---- 1534
Query: 3062 AEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNE 3121
++ +E+K +DS +G K E E +E E RN+
Sbjct: 1535 ---------SSSSDEYKQEDS----QGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQ 1581
Query: 3122 KKPMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKV 3181
K + +S E + G + K+T K R S + E++G + S
Sbjct: 1582 LKEISSSTESQKKEETKG------KGKITAGKH----RRLTRKSSTSIDEDAGRRHS--- 1628
Query: 3182 LMQNQKGKGEAGNSDSMCLRSRKTKSQ 3208
+ + +S L+ R+TKSQ
Sbjct: 1629 ----WHDEDDEAFDESPELKYRETKSQ 1651
Score = 73.2 bits (178), Expect = 4e-12
Identities = 381/1976 (19%), Positives = 666/1976 (33%), Gaps = 287/1976 (14%)
Query: 1205 PGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTS 1264
PG+ + +Q P + Q + P + + G++ K SP P+ PT
Sbjct: 252 PGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTP 311
Query: 1265 TKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGT---PVQKLD 1321
K ++ + G A +PS G K + GT PVQ
Sbjct: 312 GKPPAQQPGHEKS-------------QPGPAKPPAQPS-GLTKPLAQQPGTVKPPVQPPG 357
Query: 1322 LTE---NLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKT-TKMPCESSP 1377
T+ G + P + + G K L Q PG GKT + P + P
Sbjct: 358 TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPG-------VGKTPAQQPGPAKP 410
Query: 1378 P-ESADTPTSTRRQP------------KTPLEKRDVQK----ELSALKKLTQTSGETTHT 1420
P + TP +QP KTP+++ K + K Q +G T
Sbjct: 411 PTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPP 470
Query: 1421 DKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCT 1480
++PG P ++ S++ TK P + K Q P T
Sbjct: 471 SQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKP---PPQQPGPAKPSPQQPGST 527
Query: 1481 DKPTTHEKTTKIACRSQPDPV--DTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKA- 1537
P+ + K + + QP P S+KP S+ K K+ PS G
Sbjct: 528 KPPSQQPGSAKPSAQ-QPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK 586
Query: 1538 ------------MHTPKPAVSGEKNIYAFMGTPVQKL---DLTENLTGSKRRLQTPKEKA 1582
+H P+ A N T V L + +LT K L +
Sbjct: 587 TICPLCNTTELLLHVPEKA---NFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMK 643
Query: 1583 QALE-DLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLK------- 1634
+AL DLA Q + T T +K + + Q P K+ A + K
Sbjct: 644 RALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKP 703
Query: 1635 -------------TSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPK 1681
++ K + + L+ + + P D K + M P
Sbjct: 704 PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPT 763
Query: 1682 QILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQ 1741
L S++S T +K + + K +S+ E ++ T EK + +A
Sbjct: 764 TDLVSSSSAT-TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIP 822
Query: 1742 PDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGT 1801
D+ S P P S K + + + +K+ P + +PKP + K + T
Sbjct: 823 RPASDSKIISHPGPS-SESKGQKQVDPVQ-KKEEPKKAQTKMSPKP---DAKPMPKGSPT 877
Query: 1802 PVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFR----ELFQTPCTDNPTTDEKTTKKI 1857
P PG P + + + T ++ + E+ F + P + T E T K+
Sbjct: 878 P------PGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKL 931
Query: 1858 L---------CKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPK 1908
+ S +++ P +K+A + + S G+A P
Sbjct: 932 FGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPA 991
Query: 1909 AAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKA--KALEDLAGFKELFQTPGH 1966
++ +K+ EKL+ + +R +T K+ K + L + P
Sbjct: 992 KSIPVKKETKA---PAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTK 1048
Query: 1967 TEESMTDDKI-----TEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQT 2021
E+S + TE++ S P T T K ++ G P LT+
Sbjct: 1049 LEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCG-------FNPTPHLTEI 1101
Query: 2022 SG---KTTQTHRETAGDGKSIKAFKES-----AKQMLDPANYGTGMERWP---RTPKEEA 2070
QT R +G I+ + A M P + P + K++
Sbjct: 1102 QEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQE 1161
Query: 2071 QSLED------LAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTP 2124
Q ++ L KE TTD K + + D ++ + + P
Sbjct: 1162 QEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEK------DKASALQEKKPLP 1215
Query: 2125 LGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETA----------KQKLDPAASV 2174
K+ I EE + + +K P EDK + +T+ K ++ A
Sbjct: 1216 EEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEK 1275
Query: 2175 TGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTI 2234
+ P+T + QP + GL TP P +KTTK PQP P
Sbjct: 1276 LEGRVAPKTVQEGKQPQTKMEGLPS--GTP--QSLPKEDDKTTKTIKEQPQPPCTAKPDQ 1331
Query: 2235 FKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGT-PVQKLDLP 2293
+P +++ ++ D + S + + ++P DT + G + P + D+
Sbjct: 1332 VEPGKEKTEKEDDKSDTSSSQQPKSPQ--GLSDTGYSSDGISSSLGEIPSLIPTDEKDIL 1389
Query: 2294 GNLP----GSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDP 2349
L + P +P + A+ + E + D+ + ++KT QP
Sbjct: 1390 KGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKS-EKKTQPHEVSPEQPKD 1448
Query: 2350 VDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQ 2409
+ S + + + + +++E + +R + K P+ D K + FV+
Sbjct: 1449 QEKTQSLSETLEITISEEEIKE---SQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITT 1505
Query: 2410 KLDLLGNLPGSKRQ-----PQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSC 2464
+ + ++ S PQ + + +K+ EE +I E+S
Sbjct: 1506 RREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSA 1565
Query: 2465 KSPQPESFKTSRSSKQRLKIPL-VKVDMKEEPLAVSKLT-----RTSGETTQTHTEPTGD 2518
S Q +I + KEE K+T R + +++ + E G
Sbjct: 1566 DEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGR 1625
Query: 2519 SKSI-----KAFKESPKQILDPAAS-------VTGSR--RQLRT--------------RK 2550
S +AF ESP+ S VTG R+ +T
Sbjct: 1626 RHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESS 1685
Query: 2551 EKARAL----EDLVDFKELFSAP---GHTEESMTIDKNTKIPCKSPPP-----ELTDTAT 2598
+K +L E ++ + L +P E S ++ ++ P SP E +D++
Sbjct: 1686 QKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSP 1745
Query: 2599 STKRCPKTRPRKE----------VKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQ 2648
S K+ + RK E+ S E L + K+ + K +
Sbjct: 1746 SHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSK 1805
Query: 2649 RAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCES 2708
++KK + + + R RP+ P P+ED + EL + + E L ++ S
Sbjct: 1806 KSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAA--EMEELHRSSCSEY---S 1860
Query: 2709 PPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKE 2768
P +E VQKV + P+AV + E + KE G K +K+ +E
Sbjct: 1861 PSIESDPEGFEISPEKIIEVQKVY--KLPTAVSLYSPTDEQSIMQKE--GSQKALKSAEE 1916
Query: 2769 SAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAG------HTEESMTDDKTTK 2822
++ T + A E + E K+P G + ES+ +D T
Sbjct: 1917 MYEE----MMHKTHKYKAFPAANERDEVFE-----KEPLYGGMLIEDYIYESLVED-TYN 1966
Query: 2823 IPCKSSPELEDTATSSKRRPRTRAQKVEVKEELL--AVGKLTQTSGETTHTD---KEPVG 2877
S + + + R QK+ + E++ + K+T E +
Sbjct: 1967 GSVDGSLLTRQEEENGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQ 2026
Query: 2878 EGKGTKAFKQPAKRKL-DAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELAN 2936
E + +F P ++ D ++ S + R + E+L Q++ TPG
Sbjct: 2027 EDIVSSSFIIPESHEIVDLGTMVTSTEEERKLLDADAAYEELMKRQQMQLTPG------- 2079
Query: 2937 GAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLP 2992
S+P Q P + + R P V+S S S + S+P
Sbjct: 2080 -------SSPTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIP 2128
Score = 60.8 bits (146), Expect = 2e-08
Identities = 297/1426 (20%), Positives = 471/1426 (33%), Gaps = 270/1426 (18%)
Query: 1860 KSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINT 1919
+S Q P +P+ + +S + D++EE H G ++N
Sbjct: 120 RSEQKLPGRSPSTISLKESKS--RTDLKEE---------------HKSSMMPGFLSEVNA 162
Query: 1920 F--VGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKIT 1977
V + V K + + S+ + +K K ++ G E P ++
Sbjct: 163 LSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQ 222
Query: 1978 EVSCKSP-QPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDG 2036
+ + P Q D SS+Q KI K + GK Q +T QT D
Sbjct: 223 QGPGRDPLQQDGTPKSISSQQPEKI-------KSQPPGTGKPIQGPTQTPQT------DH 269
Query: 2037 KSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDD 2096
+ +++++ A+ G P P ++ K Q P H +
Sbjct: 270 AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPA 329
Query: 2097 KT-------TKIACKSP----PPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTH 2145
K TK + P PP P T + P PLG K Q T
Sbjct: 330 KPPAQPSGLTKPLAQQPGTVKPPVQ---PPGTTKPPAQPLGPA---------KPPAQQTG 377
Query: 2146 TDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPI 2205
++K P E G + PA G + P G +PL GL+ + P
Sbjct: 378 SEK-PSSEQPGPKALAQPPGVGKTPAQQ-PGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG 435
Query: 2206 CTDKPTTHEKTTKIACRSPQPDPVGT----PTIFKPQSKRSLRKADVEEESLALRKRTPS 2261
T P KI + P PT KP S+ A + K P
Sbjct: 436 PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPT--KPPSQLP-GPAKPPPQQPGPAKPPPQ 492
Query: 2262 VGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPG-SKRWPQTPKEKAQALEDLAGFK 2320
+ P G K P PG +K PQ P + K
Sbjct: 493 QPGSAKPPSQQPGSTKP--------------PPQQPGPAKPSPQQPGSTKPPSQQPGSAK 538
Query: 2321 ELFQTPGTDKPTTDEKTTKIA---CKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALR 2377
Q P KP+ + T ++ P P +P S KQ P + L K +
Sbjct: 539 PSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSP-SAKQPPSQGLPK--------TIC 589
Query: 2378 KRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEK------A 2431
+ + P+ A N NT E L G P P + K
Sbjct: 590 PLCNTTELLLHVPEKA-----NFNTCTECQTTVCSLCGFNP----NPHLTEVKEWLCLNC 640
Query: 2432 EALEDLVGFKELFQTPGHTEESMTDDKIT---EVSCKSPQPE--SFKTSRSSKQRL-KIP 2485
+ L G +L P + + +T VS SPQP+ S K + KQ L K P
Sbjct: 641 QMKRALGG--DLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAP 698
Query: 2486 LVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQ 2545
+ K+ P V + T + + P DS S A PK+ P+
Sbjct: 699 ----EPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA---PPKEPSVPSEQDKAPVAD 751
Query: 2546 LRTRKEK-ARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCP 2604
+ ++ K + DLV + P + ++ K+ PP TD+A ++ P
Sbjct: 752 DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKV----QSQAEEKTTPPLKTDSAKPSQSFP 807
Query: 2605 KTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRR 2664
T K + A+ R S +H P+S +G +K+ +PV++ +
Sbjct: 808 PT-GEKVSPFDSKAIPR--PASDSKIISHPGPSSESKG--------QKQVDPVQK---KE 853
Query: 2665 RPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHL 2724
P+ + K P D + S T + TAG+ P +SP
Sbjct: 854 EPKKAQTKMSPKPDAKPMPKGSPTPPGPRP--TAGQTVPTPQQSP--------------- 896
Query: 2725 RTRVQKVQVKEEPSAVKFTQTSGETTDADKEP--------AGEDKGIKALKESAKQTPAP 2776
K + + +F+ G TDA K G+ G A S
Sbjct: 897 ---------KPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947
Query: 2777 AASVTG--SRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTT----KIPCKSSPE 2830
A G S+ P AP + A PA S K+T P KS P
Sbjct: 948 TAGQPGPHSQSGPGAPMKQA-----------PAPSQPPTSQGPPKSTGQAPPAPAKSIPV 996
Query: 2831 LEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTS------GETTHTDKEPVGEGKGTKA 2884
++T + A+K+E K E K T+T ++ EP TK
Sbjct: 997 KKETKAPA-------AEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKL 1049
Query: 2885 FKQPAKRK----LDAEDVIGSRRQPR---APKEKAQ--------PLEDLASFQELSQTPG 2929
K P E IGS+ P + K Q P L QE
Sbjct: 1050 EKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNC 1109
Query: 2930 HTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNT 2989
T+ +G P PK P+ PV ++S S
Sbjct: 1110 QTQRAISGQLGDIRKMPPAP--------------SGPKASPM--------PVPTESSSQK 1147
Query: 2990 SLPPLPFKRGGGKDGSV-TGTKRLRCMPAPEEI-VEELP----ASKKQRVAPRARGKSSE 3043
+ P K ++ V T +++ E + +E++P +KQ + + K+S
Sbjct: 1148 TAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKAS- 1206
Query: 3044 PVVIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQ 3103
+ K+ L K I E++ S + K EE K PE+K + ++ E +
Sbjct: 1207 -ALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKK---PTPEDKKLLPEAKTSAPEEQKH 1262
Query: 3104 QI--TEVFVLAERIEINRNEKKPMK--TSPEMDIQNPDDGARKPIPR--DKVTENKR--- 3154
+ ++V + E++E R K ++ P+ ++ G + +P+ DK T+ +
Sbjct: 1263 DLLKSQVQIAEEKLE-GRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQP 1321
Query: 3155 ---CLRSARQNESSQPKVAEESGGQKSAKVLMQNQKGKGEAGNSDS 3197
C Q E + K +E ++ +Q+ K G SD+
Sbjct: 1322 QPPCTAKPDQVEPGKEKTEKEDDKSDTS----SSQQPKSPQGLSDT 1363
Score = 52.4 bits (124), Expect = 7e-06
Identities = 272/1367 (19%), Positives = 472/1367 (34%), Gaps = 252/1367 (18%)
Query: 957 KCAPMSDLTDL-KSLPD---TELMKDTARGQNLLQTQDHAKAPK-----------SEKGK 1001
K AP++ + + KS P T KD A Q+L + + K P S K K
Sbjct: 662 KTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAK 721
Query: 1002 ITKMPCQSLQPEPINTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETTHTHRE-PAG 1060
+P P P+ +Q KA + K+ + S + T + P+
Sbjct: 722 QPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSS 781
Query: 1061 DGKSIRTFKESPKQILDPAARVTGMKKWPRTPKE----EAQSLEDLAGFKELFQTPGPSE 1116
+S K +P D A + +P T ++ +++++ A ++ PGPS
Sbjct: 782 KVQSQAEEKTTPPLKTDSAKP---SQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSS 838
Query: 1117 ESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLALRKLTPSAGKAMLT 1176
ES ++ + K P ++ TK PK + + + P+AG+ + T
Sbjct: 839 ESKGQKQVDPVQKKEEPKKA-----QTKMSPKPDAK--PMPKGSPTPPGPRPTAGQTVPT 891
Query: 1177 PKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGF--------K 1228
P+ + ++ + F L+L K Q TP+E L GF
Sbjct: 892 PQQSPKPQEQSRRF------SLNLGSITDAPKSQPTTPQETVTG--KLFGFGASIFSQAS 943
Query: 1229 ELFQT---PGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELL-- 1283
L T PG + + P S P ST Q P + V+ E
Sbjct: 944 NLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAP 1003
Query: 1284 ACRNLMPSAGKAMHTPK-------PSVGEEKDII-----IFVGTPVQK---------LDL 1322
A L P A +A + P + + K + + T ++K L
Sbjct: 1004 AAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCK 1063
Query: 1323 TENLTGSKRRP--QTPKEEAQALEDLTGF---------KELFQTPGHTEEAVAA--GKTT 1369
TE GSK P T E + +L GF +E T+ A++ G
Sbjct: 1064 TELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIR 1123
Query: 1370 KMPCESSPPESADTPTSTRRQ-------PKTPLEKRDVQK-ELSALKKLTQTSGETTHTD 1421
KMP S P+++ P T P+ L K+ Q+ + A K + + ET +
Sbjct: 1124 KMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSME 1183
Query: 1422 KVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTD 1481
K+P + + +E +K + D A+++ K P+ K K P E+ +E + P+ +
Sbjct: 1184 KIP--PMVTTDQKQEESKLEKDKASALQEKKPLPEEK-KLIPEEEKIRSEE--KKPLLEE 1238
Query: 1482 KPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTP 1541
K T E + + TS+ + K L K V+ L R P
Sbjct: 1239 KKPTPEDKKLLP--------EAKTSAPEEQKHDLLKSQVQIAEEKLEGRV--------AP 1282
Query: 1542 KPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHT 1601
K G++ G P +G+ + L PKE
Sbjct: 1283 KTVQEGKQPQTKMEGLP----------SGTPQSL--PKE--------------------- 1309
Query: 1602 EESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTH 1661
+DKT K + QP P +++ K +++ Q
Sbjct: 1310 -----DDKTTKTIKEQPQPPCTAKP----DQVEPGKEKTEKEDDKSDTSSSQQPKSPQGL 1360
Query: 1662 THTEPTGDGKSMKAFMESPKQI-LDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTP 1720
+ T + DG S + E P I D L G K+ + + P DLA
Sbjct: 1361 SDTGYSSDGIS-SSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKL------- 1412
Query: 1721 SHTKESMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGK 1780
E T A L D + K QP + ++E +T
Sbjct: 1413 ---------ESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITI 1463
Query: 1781 AMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQ 1840
+ K + E KD TF K D ++P S + KEK++ ++++T RE +
Sbjct: 1464 SEEEIKESQEERKD--TF------KKDSQQDIPSS----KDHKEKSEFVDDITTRREPYD 1511
Query: 1841 TPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSA 1900
+ + + + ++ S S +D + + + + EE+F+ + + SA
Sbjct: 1512 SVEESSESENSPVPQRKRRTSVGSSSSD------EYKQEDSQGSGEEEDFIRKQIIEMSA 1565
Query: 1901 ---GKAMHTPKAAVGEEKDINTFV-GTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAG 1956
+ + K+I++ E+ G + K R T K ED AG
Sbjct: 1566 DEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDED-AG 1624
Query: 1957 FKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVG 2016
+ + H E+ D+ E+ + T S++ EE++ G
Sbjct: 1625 RRHSW----HDEDDEAFDESPELKYRE---------TKSQE-----------SEELVVTG 1660
Query: 2017 KLTQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDL 2076
KT + + T D S ++ ++ D P+ E +SL D
Sbjct: 1661 GGGLRRFKTIELN-STIADKYSAESSQKKTSLYFD------------EEPELEMESLTDS 1707
Query: 2077 AGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPT----------STRRRPKTPLG 2126
+ + S+ T+ + S +S +P+ R RP PL
Sbjct: 1708 PEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPL- 1766
Query: 2127 KRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKR---QPRT 2183
+E+ S ++L + K + + R+++ +K ++R +P+T
Sbjct: 1767 -LPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKT 1825
Query: 2184 PKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVG 2230
P P+ED + +EL Q + H + S + DP G
Sbjct: 1826 PPSNLSPIEDASPTEELRQ---AAEMEELHRSSCSEYSPSIESDPEG 1869
Score = 38.9 bits (89), Expect = 0.084
Identities = 93/467 (19%), Positives = 160/467 (34%), Gaps = 60/467 (12%)
Query: 2577 TIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEE---------------LSAVER 2621
T K+P +SP ST +++ R ++KEE LSAV
Sbjct: 118 TFRSEQKLPGRSP---------STISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSS 168
Query: 2622 LTQTSGQSTHTHKEPASGDEGIKVLK--QRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDL 2679
+ AS +E K K Q+ + KP + + P +++P P K Q
Sbjct: 169 VVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQG---- 224
Query: 2680 AGFTELSETSGHTQESLTAGKATKIPCESP----PLEVVDTTAST---KRHLRTRVQKVQ 2732
G L + T +S+++ + KI + P P++ T T K L+ + Q
Sbjct: 225 PGRDPLQQDG--TPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQ 282
Query: 2733 VKE---------EPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGS 2783
K+ +PS ++ + K PA + K+ AK P+
Sbjct: 283 TKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPL 342
Query: 2784 RRRP-------RAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTAT 2836
++P + P + + L K PA E + ++ P + T
Sbjct: 343 AQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPA 402
Query: 2837 SSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGE-GKGTKAFKQPAKRKLDA 2895
+ Q+V + L L Q+ + K PV + G G +Q K A
Sbjct: 403 QQPGPAKPPTQQVGTPKPLAQQPGL-QSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSA 461
Query: 2896 EDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKP 2955
+ ++ + P P + + Q PG + + T P Q P KP
Sbjct: 462 QQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGS--TKPPPQQPGPAKP 519
Query: 2956 LKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGK 3002
+ P +P S + P ++ + S P+ + G GK
Sbjct: 520 SPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS-QTGSGK 565
Score = 35.8 bits (81), Expect = 0.71
Identities = 84/386 (21%), Positives = 140/386 (36%), Gaps = 61/386 (15%)
Query: 199 ISGDFKEISSVKLVSRYGELKSVPTTQCLDNSKKNESPFWKLYESVKKELDVKSQKENVL 258
ISG +I + + +P + K P KL + K+E +VK++ E V+
Sbjct: 1115 ISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVK--KQEQEVKTEAEKVI 1172
Query: 259 QYCRKSGLQTDYATEKESADGLQGETQLLVSRKSRPKSGGSGHAVAEPASPEQEL--DQN 316
K L + + D Q E++L K S +P E++L ++
Sbjct: 1173 LEKVKETLSMEKIPPMVTTDQKQEESKL-------EKDKASALQEKKPLPEEKKLIPEEE 1225
Query: 317 KGKGRDVESVQTPSKAVGASFPLYEPAKMKTPVQYSQQQNSPQKHKNKDLYTTGRRESVN 376
K + + + + K L AK P + QKH +
Sbjct: 1226 KIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEE--------QKH--------------D 1263
Query: 377 LGKSEGFKAGDKTLTPRKLSTRNRTPAKVEDAADSATKPENLSSKTRGSIPTDVEVLPTE 436
L KS+ + KL R P V++ TK E L S T S+P + +
Sbjct: 1264 LLKSQ------VQIAEEKLEGRV-APKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKT 1316
Query: 437 TEIHNEPFLTLWLTQVERKIQKDSLSKPEKLGTTAGQMCSGLPGLSSVDINNFGDSINES 496
+ +P T QVE +K + +K T++ Q GLS D D I+ S
Sbjct: 1317 IKEQPQPPCTAKPDQVEPGKEKTE-KEDDKSDTSSSQQPKSPQGLS--DTGYSSDGISSS 1373
Query: 497 EG-----IPLKRRRVSFGGHLRPELFDENLPPNTPLKRGEAPTKRKSLVMHTPPVL---- 547
G IP + + G L+ + F + P++P + + S++ L
Sbjct: 1374 LGEIPSLIPTDEKDILKG--LKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEK 1431
Query: 548 -------KKIIKEQPQPSGKQESGSE 566
++ EQP+ K +S SE
Sbjct: 1432 SEKKTQPHEVSPEQPKDQEKTQSLSE 1457
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 75.5 bits (184), Expect = 8e-13
Identities = 328/1587 (20%), Positives = 532/1587 (33%), Gaps = 271/1587 (17%)
Query: 1723 TKESMTNEKTTKVSYRASQPDLVDTPTSSKPQ-PKRSLRKADTEEEFLAFRKQTPSA--- 1778
T +S+++++ K+ SQP P Q P+ K + + A R QT A
Sbjct: 235 TPKSISSQQPEKIK---SQPPGTGKPIQGPTQTPQTDHAKLPLQRD--ASRPQTKQADIV 289
Query: 1779 -GKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRE 1837
G+++ P+ + G P P PG + + LT +
Sbjct: 290 RGESVKPSLPSPSKPPIQQPTPGKP------PAQQPGHEKSQPGPAKPPAQPSGLT--KP 341
Query: 1838 LFQTPCTDNPTTDEKTTKKILCK--SPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRK 1895
L Q P T P T K + P PA + K ++ KA +
Sbjct: 342 LAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP------- 394
Query: 1896 LTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLG-----NLPGSKRRPQTPKEKAKA 1950
P GK TP G K VGTP G PG + P K
Sbjct: 395 --PGVGK---TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449
Query: 1951 LEDLAGFKELFQTPGHTEESMTDDKITEVSCKSP------QPDPVKTPTSSKQRLKISLG 2004
AG PG T T P QP P K P K
Sbjct: 450 PAQQAG-------PGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQ 502
Query: 2005 KVGVK----EEVLPVGKLTQTSGKTTQTHRETAGDGKSIKA---FKESAKQMLDPANY-G 2056
+ G ++ P Q G T ++ S + K SA+Q P + G
Sbjct: 503 QPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTG 562
Query: 2057 TGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDD--KTTKIACKSPPPESMDTP 2114
+G P T A+ Q P T TT++ P + +T
Sbjct: 563 SGKPLQPPTVSPSAK------------QPPSQGLPKTICPLCNTTELLLHVPEKANFNTC 610
Query: 2115 TSTRRRPKTPLGKR------DIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKL 2168
T + + G ++ E L Q+ + D P + +TA
Sbjct: 611 TECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKL--KTAPVTT 668
Query: 2169 DPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDP 2228
A S + + Q +PK A P +DL+ E + P +PT H + A + P+ D
Sbjct: 669 TSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADS 728
Query: 2229 VGTPTIFKPQSKRSLR-KADVEEES----LALRKRTPSVGKAMDTPKP--AGGDEKDMKA 2281
+ P K S S + KA V ++ ++ T V + T KP +
Sbjct: 729 LSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAE 788
Query: 2282 FMGTPVQKLDLPGNLPGSKRWPQTPKE----KAQALEDLAGFKELFQTPGTDKPTTDEKT 2337
TP K D + S+ +P T ++ ++A+ A ++ PG P+++ K
Sbjct: 789 EKTTPPLKTD---SAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPG---PSSESKG 842
Query: 2338 TKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRT-------PSAGKAMDTP 2390
K Q DPV K+ PK+ K + + + K + P+AG+ + TP
Sbjct: 843 QK------QVDPV----QKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTP 892
Query: 2391 KPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHT 2450
+ + ++ F L+L K QP TP+E L GF G +
Sbjct: 893 QQSPKPQEQSRRF------SLNLGSITDAPKSQPTTPQETVTG--KLFGF-------GAS 937
Query: 2451 EESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQ 2510
S + I+ P +S + MK+ P A S+ + G
Sbjct: 938 IFSQASNLISTAGQPGPHSQSGPGA--------------PMKQAP-APSQPPTSQGPPKS 982
Query: 2511 THTEPTGDSKSIKAFKES---PKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFS 2567
T P +KSI KE+ + L+P A + ++ T K+ + D K L +
Sbjct: 983 TGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKP----PPIKDSKSLTA 1038
Query: 2568 APGHTEESMTIDKNTK-------------IPCKSPPPELTDTATSTKRC-----PKTRPR 2609
P ++K+ K I K PP T T + C T
Sbjct: 1039 EPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHL 1098
Query: 2610 KEVKEELSA-VERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRA 2668
E++E L + SGQ K P + K P PV E S ++
Sbjct: 1099 TEIQEWLCLNCQTQRAISGQLGDIRKMPPA--------PSGPKASPMPVPTESSSQKTAV 1150
Query: 2669 PKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRV 2728
P P L E + + L K T + PP+ D + + +
Sbjct: 1151 P-----PQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKA 1205
Query: 2729 QKVQVKEE--------PSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAP---- 2776
+Q K+ P K + +K+P EDK K L E+ P
Sbjct: 1206 SALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDK--KLLPEAKTSAPEEQKHD 1263
Query: 2777 --------AASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSS 2828
A R P+ +E Q + G P+ DDKTTK K
Sbjct: 1264 LLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGL--PSGTPQSLPKEDDKTTK-TIKEQ 1320
Query: 2829 PELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQP 2888
P+ TA + P +K E +++ Q +D +G + + P
Sbjct: 1321 PQPPCTAKPDQVEP--GKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIP 1378
Query: 2889 AKRKLDAEDVI-GSRRQPRAPKEKAQPLEDLASFQE--LSQTPGHTEELANGAADSFTS- 2944
+ D +D++ G ++ + + DLA + LS LA+ ++ T
Sbjct: 1379 SLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQP 1438
Query: 2945 ---APKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGG 3001
+P+Q D K +S E + +S + +SQ + + FK+
Sbjct: 1439 HEVSPEQPKDQEKTQSLS---------ETLEITISEEEIKESQEERKDT-----FKKDSQ 1484
Query: 3002 KDGSVTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEP 3061
+D + +K + E V+++ ++++ SE + +R RTS
Sbjct: 1485 QD--IPSSKDHK---EKSEFVDDI-TTRREPYDSVEESSESENSPVPQRKRRTSVG---- 1534
Query: 3062 AEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNE 3121
++ +E+K +DS +G K E E +E E RN+
Sbjct: 1535 ---------SSSSDEYKQEDS----QGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQ 1581
Query: 3122 KKPMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKV 3181
K + +S E + G + K+T K R S + E++G + S
Sbjct: 1582 LKEISSSTESQKKEETKG------KGKITAGKH----RRLTRKSSTSIDEDAGRRHS--- 1628
Query: 3182 LMQNQKGKGEAGNSDSMCLRSRKTKSQ 3208
+ + +S L+ R+TKSQ
Sbjct: 1629 ----WHDEDDEAFDESPELKYRETKSQ 1651
Score = 73.2 bits (178), Expect = 4e-12
Identities = 381/1976 (19%), Positives = 666/1976 (33%), Gaps = 287/1976 (14%)
Query: 1205 PGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTS 1264
PG+ + +Q P + Q + P + + G++ K SP P+ PT
Sbjct: 252 PGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTP 311
Query: 1265 TKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGT---PVQKLD 1321
K ++ + G A +PS G K + GT PVQ
Sbjct: 312 GKPPAQQPGHEKS-------------QPGPAKPPAQPS-GLTKPLAQQPGTVKPPVQPPG 357
Query: 1322 LTE---NLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKT-TKMPCESSP 1377
T+ G + P + + G K L Q PG GKT + P + P
Sbjct: 358 TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPG-------VGKTPAQQPGPAKP 410
Query: 1378 P-ESADTPTSTRRQP------------KTPLEKRDVQK----ELSALKKLTQTSGETTHT 1420
P + TP +QP KTP+++ K + K Q +G T
Sbjct: 411 PTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPP 470
Query: 1421 DKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCT 1480
++PG P ++ S++ TK P + K Q P T
Sbjct: 471 SQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKP---PPQQPGPAKPSPQQPGST 527
Query: 1481 DKPTTHEKTTKIACRSQPDPV--DTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKA- 1537
P+ + K + + QP P S+KP S+ K K+ PS G
Sbjct: 528 KPPSQQPGSAKPSAQ-QPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK 586
Query: 1538 ------------MHTPKPAVSGEKNIYAFMGTPVQKL---DLTENLTGSKRRLQTPKEKA 1582
+H P+ A N T V L + +LT K L +
Sbjct: 587 TICPLCNTTELLLHVPEKA---NFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMK 643
Query: 1583 QALE-DLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLK------- 1634
+AL DLA Q + T T +K + + Q P K+ A + K
Sbjct: 644 RALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKP 703
Query: 1635 -------------TSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPK 1681
++ K + + L+ + + P D K + M P
Sbjct: 704 PPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPT 763
Query: 1682 QILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQ 1741
L S++S T +K + + K +S+ E ++ T EK + +A
Sbjct: 764 TDLVSSSSAT-TKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIP 822
Query: 1742 PDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGT 1801
D+ S P P S K + + + +K+ P + +PKP + K + T
Sbjct: 823 RPASDSKIISHPGPS-SESKGQKQVDPVQ-KKEEPKKAQTKMSPKP---DAKPMPKGSPT 877
Query: 1802 PVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFR----ELFQTPCTDNPTTDEKTTKKI 1857
P PG P + + + T ++ + E+ F + P + T E T K+
Sbjct: 878 P------PGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKL 931
Query: 1858 L---------CKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPK 1908
+ S +++ P +K+A + + S G+A P
Sbjct: 932 FGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPA 991
Query: 1909 AAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKA--KALEDLAGFKELFQTPGH 1966
++ +K+ EKL+ + +R +T K+ K + L + P
Sbjct: 992 KSIPVKKETKA---PAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTK 1048
Query: 1967 TEESMTDDKI-----TEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQT 2021
E+S + TE++ S P T T K ++ G P LT+
Sbjct: 1049 LEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCG-------FNPTPHLTEI 1101
Query: 2022 SG---KTTQTHRETAGDGKSIKAFKES-----AKQMLDPANYGTGMERWP---RTPKEEA 2070
QT R +G I+ + A M P + P + K++
Sbjct: 1102 QEWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQE 1161
Query: 2071 QSLED------LAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTP 2124
Q ++ L KE TTD K + + D ++ + + P
Sbjct: 1162 QEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEK------DKASALQEKKPLP 1215
Query: 2125 LGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETA----------KQKLDPAASV 2174
K+ I EE + + +K P EDK + +T+ K ++ A
Sbjct: 1216 EEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEK 1275
Query: 2175 TGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTI 2234
+ P+T + QP + GL TP P +KTTK PQP P
Sbjct: 1276 LEGRVAPKTVQEGKQPQTKMEGLPS--GTP--QSLPKEDDKTTKTIKEQPQPPCTAKPDQ 1331
Query: 2235 FKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGT-PVQKLDLP 2293
+P +++ ++ D + S + + ++P DT + G + P + D+
Sbjct: 1332 VEPGKEKTEKEDDKSDTSSSQQPKSPQ--GLSDTGYSSDGISSSLGEIPSLIPTDEKDIL 1389
Query: 2294 GNLP----GSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDP 2349
L + P +P + A+ + E + D+ + ++KT QP
Sbjct: 1390 KGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKS-EKKTQPHEVSPEQPKD 1448
Query: 2350 VDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQ 2409
+ S + + + + +++E + +R + K P+ D K + FV+
Sbjct: 1449 QEKTQSLSETLEITISEEEIKE---SQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITT 1505
Query: 2410 KLDLLGNLPGSKRQ-----PQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSC 2464
+ + ++ S PQ + + +K+ EE +I E+S
Sbjct: 1506 RREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSA 1565
Query: 2465 KSPQPESFKTSRSSKQRLKIPL-VKVDMKEEPLAVSKLT-----RTSGETTQTHTEPTGD 2518
S Q +I + KEE K+T R + +++ + E G
Sbjct: 1566 DEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGR 1625
Query: 2519 SKSI-----KAFKESPKQILDPAAS-------VTGSR--RQLRT--------------RK 2550
S +AF ESP+ S VTG R+ +T
Sbjct: 1626 RHSWHDEDDEAFDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESS 1685
Query: 2551 EKARAL----EDLVDFKELFSAP---GHTEESMTIDKNTKIPCKSPPP-----ELTDTAT 2598
+K +L E ++ + L +P E S ++ ++ P SP E +D++
Sbjct: 1686 QKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSP 1745
Query: 2599 STKRCPKTRPRKE----------VKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQ 2648
S K+ + RK E+ S E L + K+ + K +
Sbjct: 1746 SHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSK 1805
Query: 2649 RAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCES 2708
++KK + + + R RP+ P P+ED + EL + + E L ++ S
Sbjct: 1806 KSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAA--EMEELHRSSCSEY---S 1860
Query: 2709 PPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKE 2768
P +E VQKV + P+AV + E + KE G K +K+ +E
Sbjct: 1861 PSIESDPEGFEISPEKIIEVQKVY--KLPTAVSLYSPTDEQSIMQKE--GSQKALKSAEE 1916
Query: 2769 SAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAG------HTEESMTDDKTTK 2822
++ T + A E + E K+P G + ES+ +D T
Sbjct: 1917 MYEE----MMHKTHKYKAFPAANERDEVFE-----KEPLYGGMLIEDYIYESLVED-TYN 1966
Query: 2823 IPCKSSPELEDTATSSKRRPRTRAQKVEVKEELL--AVGKLTQTSGETTHTD---KEPVG 2877
S + + + R QK+ + E++ + K+T E +
Sbjct: 1967 GSVDGSLLTRQEEENGFMQQKGREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQ 2026
Query: 2878 EGKGTKAFKQPAKRKL-DAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELAN 2936
E + +F P ++ D ++ S + R + E+L Q++ TPG
Sbjct: 2027 EDIVSSSFIIPESHEIVDLGTMVTSTEEERKLLDADAAYEELMKRQQMQLTPG------- 2079
Query: 2937 GAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLP 2992
S+P Q P + + R P V+S S S + S+P
Sbjct: 2080 -------SSPTQAPIGEDMTESTMDFDRMPDASLTSSVLSGASLTDSTSSATLSIP 2128
Score = 60.8 bits (146), Expect = 2e-08
Identities = 297/1426 (20%), Positives = 471/1426 (33%), Gaps = 270/1426 (18%)
Query: 1860 KSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINT 1919
+S Q P +P+ + +S + D++EE H G ++N
Sbjct: 120 RSEQKLPGRSPSTISLKESKS--RTDLKEE---------------HKSSMMPGFLSEVNA 162
Query: 1920 F--VGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKIT 1977
V + V K + + S+ + +K K ++ G E P ++
Sbjct: 163 LSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQ 222
Query: 1978 EVSCKSP-QPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDG 2036
+ + P Q D SS+Q KI K + GK Q +T QT D
Sbjct: 223 QGPGRDPLQQDGTPKSISSQQPEKI-------KSQPPGTGKPIQGPTQTPQT------DH 269
Query: 2037 KSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDD 2096
+ +++++ A+ G P P ++ K Q P H +
Sbjct: 270 AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPA 329
Query: 2097 KT-------TKIACKSP----PPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTH 2145
K TK + P PP P T + P PLG K Q T
Sbjct: 330 KPPAQPSGLTKPLAQQPGTVKPPVQ---PPGTTKPPAQPLGPA---------KPPAQQTG 377
Query: 2146 TDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPI 2205
++K P E G + PA G + P G +PL GL+ + P
Sbjct: 378 SEK-PSSEQPGPKALAQPPGVGKTPAQQ-PGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG 435
Query: 2206 CTDKPTTHEKTTKIACRSPQPDPVGT----PTIFKPQSKRSLRKADVEEESLALRKRTPS 2261
T P KI + P PT KP S+ A + K P
Sbjct: 436 PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPT--KPPSQLP-GPAKPPPQQPGPAKPPPQ 492
Query: 2262 VGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPG-SKRWPQTPKEKAQALEDLAGFK 2320
+ P G K P PG +K PQ P + K
Sbjct: 493 QPGSAKPPSQQPGSTKP--------------PPQQPGPAKPSPQQPGSTKPPSQQPGSAK 538
Query: 2321 ELFQTPGTDKPTTDEKTTKIA---CKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALR 2377
Q P KP+ + T ++ P P +P S KQ P + L K +
Sbjct: 539 PSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSP-SAKQPPSQGLPK--------TIC 589
Query: 2378 KRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEK------A 2431
+ + P+ A N NT E L G P P + K
Sbjct: 590 PLCNTTELLLHVPEKA-----NFNTCTECQTTVCSLCGFNP----NPHLTEVKEWLCLNC 640
Query: 2432 EALEDLVGFKELFQTPGHTEESMTDDKIT---EVSCKSPQPE--SFKTSRSSKQRL-KIP 2485
+ L G +L P + + +T VS SPQP+ S K + KQ L K P
Sbjct: 641 QMKRALGG--DLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAP 698
Query: 2486 LVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQ 2545
+ K+ P V + T + + P DS S A PK+ P+
Sbjct: 699 ----EPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA---PPKEPSVPSEQDKAPVAD 751
Query: 2546 LRTRKEK-ARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCP 2604
+ ++ K + DLV + P + ++ K+ PP TD+A ++ P
Sbjct: 752 DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKV----QSQAEEKTTPPLKTDSAKPSQSFP 807
Query: 2605 KTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRR 2664
T K + A+ R S +H P+S +G +K+ +PV++ +
Sbjct: 808 PT-GEKVSPFDSKAIPR--PASDSKIISHPGPSSESKG--------QKQVDPVQK---KE 853
Query: 2665 RPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHL 2724
P+ + K P D + S T + TAG+ P +SP
Sbjct: 854 EPKKAQTKMSPKPDAKPMPKGSPTPPGPRP--TAGQTVPTPQQSP--------------- 896
Query: 2725 RTRVQKVQVKEEPSAVKFTQTSGETTDADKEP--------AGEDKGIKALKESAKQTPAP 2776
K + + +F+ G TDA K G+ G A S
Sbjct: 897 ---------KPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947
Query: 2777 AASVTG--SRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTT----KIPCKSSPE 2830
A G S+ P AP + A PA S K+T P KS P
Sbjct: 948 TAGQPGPHSQSGPGAPMKQA-----------PAPSQPPTSQGPPKSTGQAPPAPAKSIPV 996
Query: 2831 LEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTS------GETTHTDKEPVGEGKGTKA 2884
++T + A+K+E K E K T+T ++ EP TK
Sbjct: 997 KKETKAPA-------AEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKL 1049
Query: 2885 FKQPAKRK----LDAEDVIGSRRQPR---APKEKAQ--------PLEDLASFQELSQTPG 2929
K P E IGS+ P + K Q P L QE
Sbjct: 1050 EKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNC 1109
Query: 2930 HTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNT 2989
T+ +G P PK P+ PV ++S S
Sbjct: 1110 QTQRAISGQLGDIRKMPPAP--------------SGPKASPM--------PVPTESSSQK 1147
Query: 2990 SLPPLPFKRGGGKDGSV-TGTKRLRCMPAPEEI-VEELP----ASKKQRVAPRARGKSSE 3043
+ P K ++ V T +++ E + +E++P +KQ + + K+S
Sbjct: 1148 TAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKAS- 1206
Query: 3044 PVVIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQ 3103
+ K+ L K I E++ S + K EE K PE+K + ++ E +
Sbjct: 1207 -ALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKK---PTPEDKKLLPEAKTSAPEEQKH 1262
Query: 3104 QI--TEVFVLAERIEINRNEKKPMK--TSPEMDIQNPDDGARKPIPR--DKVTENKR--- 3154
+ ++V + E++E R K ++ P+ ++ G + +P+ DK T+ +
Sbjct: 1263 DLLKSQVQIAEEKLE-GRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQP 1321
Query: 3155 ---CLRSARQNESSQPKVAEESGGQKSAKVLMQNQKGKGEAGNSDS 3197
C Q E + K +E ++ +Q+ K G SD+
Sbjct: 1322 QPPCTAKPDQVEPGKEKTEKEDDKSDTS----SSQQPKSPQGLSDT 1363
Score = 52.4 bits (124), Expect = 7e-06
Identities = 272/1367 (19%), Positives = 472/1367 (34%), Gaps = 252/1367 (18%)
Query: 957 KCAPMSDLTDL-KSLPD---TELMKDTARGQNLLQTQDHAKAPK-----------SEKGK 1001
K AP++ + + KS P T KD A Q+L + + K P S K K
Sbjct: 662 KTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAK 721
Query: 1002 ITKMPCQSLQPEPINTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETTHTHRE-PAG 1060
+P P P+ +Q KA + K+ + S + T + P+
Sbjct: 722 QPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSS 781
Query: 1061 DGKSIRTFKESPKQILDPAARVTGMKKWPRTPKE----EAQSLEDLAGFKELFQTPGPSE 1116
+S K +P D A + +P T ++ +++++ A ++ PGPS
Sbjct: 782 KVQSQAEEKTTPPLKTDSAKP---SQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSS 838
Query: 1117 ESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLALRKLTPSAGKAMLT 1176
ES ++ + K P ++ TK PK + + + P+AG+ + T
Sbjct: 839 ESKGQKQVDPVQKKEEPKKA-----QTKMSPKPDAK--PMPKGSPTPPGPRPTAGQTVPT 891
Query: 1177 PKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGF--------K 1228
P+ + ++ + F L+L K Q TP+E L GF
Sbjct: 892 PQQSPKPQEQSRRF------SLNLGSITDAPKSQPTTPQETVTG--KLFGFGASIFSQAS 943
Query: 1229 ELFQT---PGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELL-- 1283
L T PG + + P S P ST Q P + V+ E
Sbjct: 944 NLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAP 1003
Query: 1284 ACRNLMPSAGKAMHTPK-------PSVGEEKDII-----IFVGTPVQK---------LDL 1322
A L P A +A + P + + K + + T ++K L
Sbjct: 1004 AAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCK 1063
Query: 1323 TENLTGSKRRP--QTPKEEAQALEDLTGF---------KELFQTPGHTEEAVAA--GKTT 1369
TE GSK P T E + +L GF +E T+ A++ G
Sbjct: 1064 TELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIR 1123
Query: 1370 KMPCESSPPESADTPTSTRRQ-------PKTPLEKRDVQK-ELSALKKLTQTSGETTHTD 1421
KMP S P+++ P T P+ L K+ Q+ + A K + + ET +
Sbjct: 1124 KMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSME 1183
Query: 1422 KVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTD 1481
K+P + + +E +K + D A+++ K P+ K K P E+ +E + P+ +
Sbjct: 1184 KIP--PMVTTDQKQEESKLEKDKASALQEKKPLPEEK-KLIPEEEKIRSEE--KKPLLEE 1238
Query: 1482 KPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTP 1541
K T E + + TS+ + K L K V+ L R P
Sbjct: 1239 KKPTPEDKKLLP--------EAKTSAPEEQKHDLLKSQVQIAEEKLEGRV--------AP 1282
Query: 1542 KPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHT 1601
K G++ G P +G+ + L PKE
Sbjct: 1283 KTVQEGKQPQTKMEGLP----------SGTPQSL--PKE--------------------- 1309
Query: 1602 EESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTH 1661
+DKT K + QP P +++ K +++ Q
Sbjct: 1310 -----DDKTTKTIKEQPQPPCTAKP----DQVEPGKEKTEKEDDKSDTSSSQQPKSPQGL 1360
Query: 1662 THTEPTGDGKSMKAFMESPKQI-LDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTP 1720
+ T + DG S + E P I D L G K+ + + P DLA
Sbjct: 1361 SDTGYSSDGIS-SSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKL------- 1412
Query: 1721 SHTKESMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGK 1780
E T A L D + K QP + ++E +T
Sbjct: 1413 ---------ESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITI 1463
Query: 1781 AMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQ 1840
+ K + E KD TF K D ++P S + KEK++ ++++T RE +
Sbjct: 1464 SEEEIKESQEERKD--TF------KKDSQQDIPSS----KDHKEKSEFVDDITTRREPYD 1511
Query: 1841 TPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSA 1900
+ + + + ++ S S +D + + + + EE+F+ + + SA
Sbjct: 1512 SVEESSESENSPVPQRKRRTSVGSSSSD------EYKQEDSQGSGEEEDFIRKQIIEMSA 1565
Query: 1901 ---GKAMHTPKAAVGEEKDINTFV-GTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAG 1956
+ + K+I++ E+ G + K R T K ED AG
Sbjct: 1566 DEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDED-AG 1624
Query: 1957 FKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVG 2016
+ + H E+ D+ E+ + T S++ EE++ G
Sbjct: 1625 RRHSW----HDEDDEAFDESPELKYRE---------TKSQE-----------SEELVVTG 1660
Query: 2017 KLTQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDL 2076
KT + + T D S ++ ++ D P+ E +SL D
Sbjct: 1661 GGGLRRFKTIELN-STIADKYSAESSQKKTSLYFD------------EEPELEMESLTDS 1707
Query: 2077 AGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPT----------STRRRPKTPLG 2126
+ + S+ T+ + S +S +P+ R RP PL
Sbjct: 1708 PEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPL- 1766
Query: 2127 KRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKR---QPRT 2183
+E+ S ++L + K + + R+++ +K ++R +P+T
Sbjct: 1767 -LPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERPKT 1825
Query: 2184 PKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVG 2230
P P+ED + +EL Q + H + S + DP G
Sbjct: 1826 PPSNLSPIEDASPTEELRQ---AAEMEELHRSSCSEYSPSIESDPEG 1869
Score = 38.9 bits (89), Expect = 0.084
Identities = 93/467 (19%), Positives = 160/467 (34%), Gaps = 60/467 (12%)
Query: 2577 TIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEE---------------LSAVER 2621
T K+P +SP ST +++ R ++KEE LSAV
Sbjct: 118 TFRSEQKLPGRSP---------STISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSS 168
Query: 2622 LTQTSGQSTHTHKEPASGDEGIKVLK--QRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDL 2679
+ AS +E K K Q+ + KP + + P +++P P K Q
Sbjct: 169 VVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQG---- 224
Query: 2680 AGFTELSETSGHTQESLTAGKATKIPCESP----PLEVVDTTAST---KRHLRTRVQKVQ 2732
G L + T +S+++ + KI + P P++ T T K L+ + Q
Sbjct: 225 PGRDPLQQDG--TPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQ 282
Query: 2733 VKE---------EPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGS 2783
K+ +PS ++ + K PA + K+ AK P+
Sbjct: 283 TKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPL 342
Query: 2784 RRRP-------RAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTAT 2836
++P + P + + L K PA E + ++ P + T
Sbjct: 343 AQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPA 402
Query: 2837 SSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGE-GKGTKAFKQPAKRKLDA 2895
+ Q+V + L L Q+ + K PV + G G +Q K A
Sbjct: 403 QQPGPAKPPTQQVGTPKPLAQQPGL-QSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSA 461
Query: 2896 EDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKP 2955
+ ++ + P P + + Q PG + + T P Q P KP
Sbjct: 462 QQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGS--TKPPPQQPGPAKP 519
Query: 2956 LKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGK 3002
+ P +P S + P ++ + S P+ + G GK
Sbjct: 520 SPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS-QTGSGK 565
Score = 35.8 bits (81), Expect = 0.71
Identities = 84/386 (21%), Positives = 140/386 (36%), Gaps = 61/386 (15%)
Query: 199 ISGDFKEISSVKLVSRYGELKSVPTTQCLDNSKKNESPFWKLYESVKKELDVKSQKENVL 258
ISG +I + + +P + K P KL + K+E +VK++ E V+
Sbjct: 1115 ISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVK--KQEQEVKTEAEKVI 1172
Query: 259 QYCRKSGLQTDYATEKESADGLQGETQLLVSRKSRPKSGGSGHAVAEPASPEQEL--DQN 316
K L + + D Q E++L K S +P E++L ++
Sbjct: 1173 LEKVKETLSMEKIPPMVTTDQKQEESKL-------EKDKASALQEKKPLPEEKKLIPEEE 1225
Query: 317 KGKGRDVESVQTPSKAVGASFPLYEPAKMKTPVQYSQQQNSPQKHKNKDLYTTGRRESVN 376
K + + + + K L AK P + QKH +
Sbjct: 1226 KIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEE--------QKH--------------D 1263
Query: 377 LGKSEGFKAGDKTLTPRKLSTRNRTPAKVEDAADSATKPENLSSKTRGSIPTDVEVLPTE 436
L KS+ + KL R P V++ TK E L S T S+P + +
Sbjct: 1264 LLKSQ------VQIAEEKLEGRV-APKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKT 1316
Query: 437 TEIHNEPFLTLWLTQVERKIQKDSLSKPEKLGTTAGQMCSGLPGLSSVDINNFGDSINES 496
+ +P T QVE +K + +K T++ Q GLS D D I+ S
Sbjct: 1317 IKEQPQPPCTAKPDQVEPGKEKTE-KEDDKSDTSSSQQPKSPQGLS--DTGYSSDGISSS 1373
Query: 497 EG-----IPLKRRRVSFGGHLRPELFDENLPPNTPLKRGEAPTKRKSLVMHTPPVL---- 547
G IP + + G L+ + F + P++P + + S++ L
Sbjct: 1374 LGEIPSLIPTDEKDILKG--LKKDSFSQESSPSSPSDLAKLESTVLSILEAQASTLADEK 1431
Query: 548 -------KKIIKEQPQPSGKQESGSE 566
++ EQP+ K +S SE
Sbjct: 1432 SEKKTQPHEVSPEQPKDQEKTQSLSE 1457
>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
Length = 2812
Score = 69.3 bits (168), Expect = 6e-11
Identities = 109/501 (21%), Positives = 183/501 (36%), Gaps = 62/501 (12%)
Query: 1232 QTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMPS 1291
+T G TE + K + + P S + PT K++P K + E + +PS
Sbjct: 555 ETTGLTENPTISTKKPTVSIEKP-SVTTEKPTVPKEKPTIPTEKPTISTE----KPTIPS 609
Query: 1292 AGKAMHTPKPSVGEEKDIIIFVGT--PVQKLDL-TENLTGSKRRPQTPKEEAQALEDLTG 1348
M + KP++ EK I+ P +K + +E T S +P P EE +
Sbjct: 610 EKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTE--- 666
Query: 1349 FKELFQTPGHTEEAVAAGKTTKMPCE--SSPPE-----------SADTPTSTRRQPKTPL 1395
+T EE V + +P E S P E S + PT + +P P
Sbjct: 667 -----ETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPT 721
Query: 1396 EKRDVQKELSAL---KKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLDPAA-SVTGS 1451
EK + E S + K T T T T+K +K T K + P ++
Sbjct: 722 EKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP---TEKPTISPEKLTIPTE 778
Query: 1452 KRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQS 1511
K T++ P E + + T++PTT + T I+ P++ PT ++
Sbjct: 779 KPTIPTEKPTIPTE---------KPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEET 829
Query: 1512 KRSLRKVDVEEEFFALRKRTPSAG---KAMHTPKPAVSGEKNIYAFMGTPVQKLDL---- 1564
S+ + + E + P+ + T KP +S EK + P +KL +
Sbjct: 830 TTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEK-----LTIPTEKLTIPTEK 884
Query: 1565 ----TENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQP 1620
E T S +L P EK + T + ++ ++T K + P
Sbjct: 885 PTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIP 944
Query: 1621 DPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFM-ES 1679
+ K + T + ++ + KLT + + T +PT + + A
Sbjct: 945 TEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPH 1004
Query: 1680 PKQILDSAASLTGSKRQLRTP 1700
P A+L S TP
Sbjct: 1005 PSPTATGLAALVMSPHAPSTP 1025
Score = 63.5 bits (153), Expect = 3e-09
Identities = 125/542 (23%), Positives = 186/542 (34%), Gaps = 66/542 (12%)
Query: 1962 QTPGHTEESMTDDKITEVSCKSPQPD------PVKTPTSSKQRLKISLGKVGVKEEV--L 2013
+T G TE K VS + P P + PT ++ IS K + E +
Sbjct: 555 ETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNM 614
Query: 2014 PVGKLTQTSGKTT-QTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQ- 2071
P K T S K T T + T S K S K + E P TP EE
Sbjct: 615 PSEKPTIPSEKPTILTEKPTI---PSEKPTIPSEKPTISTEKPTVPTEE-PTTPTEETTT 670
Query: 2072 SLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIV 2131
S+E+ E P T+ T + S + PT + +P P K I
Sbjct: 671 SMEEPVIPTEKPSIPTEKPSIPTEKPTISM---EETIISTEKPTISPEKPTIPTEKPTIP 727
Query: 2132 EELSALKQLTQTTHTDK--VPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQ 2189
E S + TT T+K +P T K + P T +++ +P+
Sbjct: 728 TEKSTISPEKPTTPTEKPTIP------------TEKPTISPEKPTTPTEKPTISPEKLTI 775
Query: 2190 PLEDLAGLKELFQTP-----ICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLR 2244
P E E P I T++PTT + T I+ P P+ PT+ ++ S+
Sbjct: 776 PTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPMEKPTLPTEETTTSVE 834
Query: 2245 KADVEEESLALRKRTPSVG---KAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPG--- 2298
+ + E L + P++ + T KP EK + P +KL +P P
Sbjct: 835 ETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEK-----LTIPTEKLTIPTEKPTIPI 889
Query: 2299 -----SKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKS---PQPDPV 2350
S P EK + T T+KPT + T I+ + P P
Sbjct: 890 EETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPT 949
Query: 2351 DTPAS---TKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETP 2407
+P ++P + K + E L + P+ + T KP + EK P
Sbjct: 950 ISPEKLTIPTEKPTISTEKPTIPTEKLTI----PTEKPTIPTEKPTIPTEKLTALRPPHP 1005
Query: 2408 VQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSP 2467
L L S P TP + P + + SCKSP
Sbjct: 1006 SPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCP---PNARYESCACPASCKSP 1062
Query: 2468 QP 2469
+P
Sbjct: 1063 RP 1064
Score = 51.2 bits (121), Expect = 2e-05
Identities = 110/516 (21%), Positives = 186/516 (36%), Gaps = 78/516 (15%)
Query: 2445 QTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRT 2504
+T G TE K VS + P + K + K++ IP K + E K T
Sbjct: 555 ETTGLTENPTISTKKPTVSIEKPSVTTEKPT-VPKEKPTIPTEKPTISTE-----KPTIP 608
Query: 2505 SGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKE 2564
S + +PT S+ E P I ++ + + T K E +E
Sbjct: 609 SEKPNMPSEKPTIPSEKPTILTEKPT-IPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEE 667
Query: 2565 LFSAPGH----TEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVE 2620
++ TE+ + IP + P + +T ST++ P P K E
Sbjct: 668 TTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEK-PTISPEKPT----IPTE 722
Query: 2621 RLTQTSGQSTHTHKEPASGDEGIKVLKQR---AKKKPNPVEEEPS---------RRRPRA 2668
+ T + +ST + ++P + E + ++ + +KP E+P+ +P
Sbjct: 723 KPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTI 782
Query: 2669 PKEKAQ-PLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTR 2727
P EK P E TE E + T+E+ + + IP E P L +TT S + +
Sbjct: 783 PTEKPTIPTEKPTISTE--EPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIST 840
Query: 2728 VQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRP 2787
+ E+P+ T T +K +K P +T +P
Sbjct: 841 EKLTIPMEKPT----ISTEKPTIPTEKPTISPEK-----------LTIPTEKLTIPTEKP 885
Query: 2788 RAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQ 2847
P E E +++ +K T IP + + T S +P +
Sbjct: 886 TIPIE-------------------ETTISTEKLT-IPTEKPTISPEKPTISTEKPTIPTE 925
Query: 2848 K--VEVKEELLAVGKLT-QTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQ 2904
K + +E ++ KLT T T +K + K T + ++P + E + +
Sbjct: 926 KPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPT---IPTEKLTIPTEK 982
Query: 2905 PRAPKEKAQ-PLEDLASFQELSQTPGHTEELANGAA 2939
P P EK P E L + + P H A G A
Sbjct: 983 PTIPTEKPTIPTEKLTALR-----PPHPSPTATGLA 1013
>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
Length = 2721
Score = 69.3 bits (168), Expect = 6e-11
Identities = 109/501 (21%), Positives = 183/501 (36%), Gaps = 62/501 (12%)
Query: 1232 QTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMPS 1291
+T G TE + K + + P S + PT K++P K + E + +PS
Sbjct: 555 ETTGLTENPTISTKKPTVSIEKP-SVTTEKPTVPKEKPTIPTEKPTISTE----KPTIPS 609
Query: 1292 AGKAMHTPKPSVGEEKDIIIFVGT--PVQKLDL-TENLTGSKRRPQTPKEEAQALEDLTG 1348
M + KP++ EK I+ P +K + +E T S +P P EE +
Sbjct: 610 EKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTE--- 666
Query: 1349 FKELFQTPGHTEEAVAAGKTTKMPCE--SSPPE-----------SADTPTSTRRQPKTPL 1395
+T EE V + +P E S P E S + PT + +P P
Sbjct: 667 -----ETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPT 721
Query: 1396 EKRDVQKELSAL---KKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLDPAA-SVTGS 1451
EK + E S + K T T T T+K +K T K + P ++
Sbjct: 722 EKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP---TEKPTISPEKLTIPTE 778
Query: 1452 KRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQS 1511
K T++ P E + + T++PTT + T I+ P++ PT ++
Sbjct: 779 KPTIPTEKPTIPTE---------KPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEET 829
Query: 1512 KRSLRKVDVEEEFFALRKRTPSAG---KAMHTPKPAVSGEKNIYAFMGTPVQKLDL---- 1564
S+ + + E + P+ + T KP +S EK + P +KL +
Sbjct: 830 TTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEK-----LTIPTEKLTIPTEK 884
Query: 1565 ----TENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQP 1620
E T S +L P EK + T + ++ ++T K + P
Sbjct: 885 PTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIP 944
Query: 1621 DPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFM-ES 1679
+ K + T + ++ + KLT + + T +PT + + A
Sbjct: 945 TEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKLTALRPPH 1004
Query: 1680 PKQILDSAASLTGSKRQLRTP 1700
P A+L S TP
Sbjct: 1005 PSPTATGLAALVMSPHAPSTP 1025
Score = 63.5 bits (153), Expect = 3e-09
Identities = 125/542 (23%), Positives = 186/542 (34%), Gaps = 66/542 (12%)
Query: 1962 QTPGHTEESMTDDKITEVSCKSPQPD------PVKTPTSSKQRLKISLGKVGVKEEV--L 2013
+T G TE K VS + P P + PT ++ IS K + E +
Sbjct: 555 ETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNM 614
Query: 2014 PVGKLTQTSGKTT-QTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQ- 2071
P K T S K T T + T S K S K + E P TP EE
Sbjct: 615 PSEKPTIPSEKPTILTEKPTI---PSEKPTIPSEKPTISTEKPTVPTEE-PTTPTEETTT 670
Query: 2072 SLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIV 2131
S+E+ E P T+ T + S + PT + +P P K I
Sbjct: 671 SMEEPVIPTEKPSIPTEKPSIPTEKPTISM---EETIISTEKPTISPEKPTIPTEKPTIP 727
Query: 2132 EELSALKQLTQTTHTDK--VPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQ 2189
E S + TT T+K +P T K + P T +++ +P+
Sbjct: 728 TEKSTISPEKPTTPTEKPTIP------------TEKPTISPEKPTTPTEKPTISPEKLTI 775
Query: 2190 PLEDLAGLKELFQTP-----ICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLR 2244
P E E P I T++PTT + T I+ P P+ PT+ ++ S+
Sbjct: 776 PTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPS-IPMEKPTLPTEETTTSVE 834
Query: 2245 KADVEEESLALRKRTPSVG---KAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPG--- 2298
+ + E L + P++ + T KP EK + P +KL +P P
Sbjct: 835 ETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEK-----LTIPTEKLTIPTEKPTIPI 889
Query: 2299 -----SKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKS---PQPDPV 2350
S P EK + T T+KPT + T I+ + P P
Sbjct: 890 EETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPT 949
Query: 2351 DTPAS---TKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETP 2407
+P ++P + K + E L + P+ + T KP + EK P
Sbjct: 950 ISPEKLTIPTEKPTISTEKPTIPTEKLTI----PTEKPTIPTEKPTIPTEKLTALRPPHP 1005
Query: 2408 VQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSP 2467
L L S P TP + P + + SCKSP
Sbjct: 1006 SPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTERCP---PNARYESCACPASCKSP 1062
Query: 2468 QP 2469
+P
Sbjct: 1063 RP 1064
Score = 51.2 bits (121), Expect = 2e-05
Identities = 110/516 (21%), Positives = 186/516 (36%), Gaps = 78/516 (15%)
Query: 2445 QTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRT 2504
+T G TE K VS + P + K + K++ IP K + E K T
Sbjct: 555 ETTGLTENPTISTKKPTVSIEKPSVTTEKPT-VPKEKPTIPTEKPTISTE-----KPTIP 608
Query: 2505 SGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKE 2564
S + +PT S+ E P I ++ + + T K E +E
Sbjct: 609 SEKPNMPSEKPTIPSEKPTILTEKPT-IPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEE 667
Query: 2565 LFSAPGH----TEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVE 2620
++ TE+ + IP + P + +T ST++ P P K E
Sbjct: 668 TTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEK-PTISPEKPT----IPTE 722
Query: 2621 RLTQTSGQSTHTHKEPASGDEGIKVLKQR---AKKKPNPVEEEPS---------RRRPRA 2668
+ T + +ST + ++P + E + ++ + +KP E+P+ +P
Sbjct: 723 KPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTI 782
Query: 2669 PKEKAQ-PLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTR 2727
P EK P E TE E + T+E+ + + IP E P L +TT S + +
Sbjct: 783 PTEKPTIPTEKPTISTE--EPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIST 840
Query: 2728 VQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRP 2787
+ E+P+ T T +K +K P +T +P
Sbjct: 841 EKLTIPMEKPT----ISTEKPTIPTEKPTISPEK-----------LTIPTEKLTIPTEKP 885
Query: 2788 RAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQ 2847
P E E +++ +K T IP + + T S +P +
Sbjct: 886 TIPIE-------------------ETTISTEKLT-IPTEKPTISPEKPTISTEKPTIPTE 925
Query: 2848 K--VEVKEELLAVGKLT-QTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQ 2904
K + +E ++ KLT T T +K + K T + ++P + E + +
Sbjct: 926 KPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPT---IPTEKLTIPTEK 982
Query: 2905 PRAPKEKAQ-PLEDLASFQELSQTPGHTEELANGAA 2939
P P EK P E L + + P H A G A
Sbjct: 983 PTIPTEKPTIPTEKLTALR-----PPHPSPTATGLA 1013
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 65.9 bits (159), Expect = 6e-10
Identities = 309/1502 (20%), Positives = 510/1502 (33%), Gaps = 221/1502 (14%)
Query: 1882 KKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRP 1941
+K EE+ K T + + + EE + T TP +L + P
Sbjct: 61 RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATP--RLASTNSSVLGADLP 118
Query: 1942 QTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTS-SKQRLK 2000
+ KEKAKA + AG T +++ + + KS +P T S +++
Sbjct: 119 SSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGS 178
Query: 2001 ISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGK-SIK---------AFKESAKQML 2050
+ K ++ G+ +S T+ + ET +GK S+K + KES +
Sbjct: 179 VPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKA 238
Query: 2051 DPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPES 2110
PA G TP+ + +L K+ + + +EE + ++
Sbjct: 239 APAPGKVG----DVTPQVKGGALPPAKRAKKPEEESESSEEGSESEE------------- 281
Query: 2111 MDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDP 2170
+ P TR + K I++ +A T P K V +T K +
Sbjct: 282 -EAPAGTRSQVKA---SEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEE 337
Query: 2171 ---AASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPD 2227
++S S + TP KA +G + + E K A +P P
Sbjct: 338 DSESSSEESSDSEEETPAAKALLQAKASGKT----SQVGAASAPAKESPRKGAAPAP-PG 392
Query: 2228 PVGTPTIFKPQ-------SKRSLRKADVEEESLALRK---RTPSV----GKAMDTPKPAG 2273
G P + K Q S+ S ++D EEE+ A K + P V A ++P+
Sbjct: 393 KTG-PAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGA 451
Query: 2274 GDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTT 2333
K ++ S +A A + A K L ++P +T
Sbjct: 452 APAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPAST 511
Query: 2334 DEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPA 2393
P P PA+ P + K + + E + S G+ PA
Sbjct: 512 MGMGPLGKGAGPVPPGKVGPAT----PSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPA 567
Query: 2394 VSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEES 2453
EK++ ++ G P K P + KAE D + E
Sbjct: 568 --QEKSLGNILQAKPTSSPAKG--PPQKAGPVAVQVKAEKPMD----------NSESSEE 613
Query: 2454 MTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQ--- 2510
+D S S + + T+ +K LKIP K K+ S TQ
Sbjct: 614 SSD------SADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPR 667
Query: 2511 ---THTEPTGDSKSIKAFKESP------KQILDPAASVTGSRRQLRTRKEKARALEDLVD 2561
T T P G S ++ + P + D TG + K + L+
Sbjct: 668 KAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAA 727
Query: 2562 FKELFSA---------PGHTEESMTIDKNTKIPCKSPPPELTDT--ATSTKRCPKTRPRK 2610
+ + PG T ++T K K E +D+ A ++ KT +K
Sbjct: 728 SVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKK 787
Query: 2611 EVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPK 2670
+ A R G T P KQR+ K P P A
Sbjct: 788 TQAKANPAAARAPSAKG----TISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARG 843
Query: 2671 EKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRT---R 2727
+ P A T +G ++S ++ + ES E +T A K +T R
Sbjct: 844 PASVPSVGKAVATAAQAQTGPEEDSGSSEE------ESDSEEEAETLAQVKPSGKTHQIR 897
Query: 2728 VQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRP 2787
KE P G+T + + +D + +ES APAA
Sbjct: 898 AALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVT------- 950
Query: 2788 RAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQ 2847
SAQ I+ F DP + T + S+P + S+ R + ++
Sbjct: 951 -----SAQVIKPPLIFVDPNRSPAGPAATP---AQAQAASTPRKARASESTARSSSSESE 1002
Query: 2848 KVEV--KEELLAVGKLTQT-SGETTHTDKEPVGEGKGTKAFKQPAK----RKLDAEDVIG 2900
+V + L G T + T H P G + K+ ++ +K +
Sbjct: 1003 DEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQV 1062
Query: 2901 SRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKPLKISR 2960
S++ P + L+ LA +Q P + ++G + + P +P S
Sbjct: 1063 SKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGT 1122
Query: 2961 RVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDG-SVTGTKRLRCM-PAP 3018
LR PK+ V +T+ P S ++S G +DG G K + P P
Sbjct: 1123 NKLRKPKLPEVQQ--ATKAPESSDDSEDSS----DSSSGSEEDGEGPQGAKSAHTLGPTP 1176
Query: 3019 ---EEIVEELPA--SKKQRVAPR---ARGKSSEPVVIMKRSLRTSAKRIEPAEELNS--- 3067
E +VEE A S+ VAP G + + + +++ + ++S
Sbjct: 1177 SRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLA 1236
Query: 3068 -NDMKTNKEEHKLQDSV----PENKG-------ISLRSRRQNK----------------- 3098
D K+E K Q + P+ G +SR+ K
Sbjct: 1237 AKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNIT 1296
Query: 3099 ----------TEAEQQITEVFVLAERIEINRNEKKPMKTSPEMDIQNPDDGARK-----P 3143
EA+ Q + V VL E +E R KK + T+ E + + RK P
Sbjct: 1297 QCLLGQPWPLNEAQVQASVVKVLTELLEQER--KKVVDTTKESSRKGWESRKRKLSGDQP 1354
Query: 3144 IPRDKVTENKRCLRSARQNES--SQPKVAEESGG---QKSAKVLMQNQKGKGEAGNSDSM 3198
R ++ K+ L + E+ S K + S G + A ++ +KGKG G+ +
Sbjct: 1355 AARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAK 1414
Query: 3199 CLRSRKTKSQPAASTLES------KSVQRVTRSVKRCAENPKKAEDNVCVKKIRTRSHRD 3252
+ + Q T+E KS + +S KR + KK + KK + S +D
Sbjct: 1415 --DEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKK----KKAKKASTKD 1468
Query: 3253 SE 3254
SE
Sbjct: 1469 SE 1470
Score = 52.0 bits (123), Expect = 1e-05
Identities = 129/674 (19%), Positives = 239/674 (35%), Gaps = 126/674 (18%)
Query: 2590 PPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQR 2649
P L D T ++ + +++ +E+ + + T+ S + + S +E + +
Sbjct: 43 PVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSE----SSEEEEEAEAET 98
Query: 2650 AKKKPNPVEEEPS---RRRPRAPKEKAQPLEDLAGFTELS---ETSGHTQESLTAGKATK 2703
AK P S P + KEKA+ + AG T S +G T +L +GK+ +
Sbjct: 99 AKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPR 158
Query: 2704 IPCESPPLEVVDTTASTKRH-------LRTRVQKVQVKEEPSAVKFTQTSGETTDADKEP 2756
E P + T+ + V + S+ + T +S + TD + +P
Sbjct: 159 KSAE--PSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKP 216
Query: 2757 AGEDKGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMT 2816
+ + +KA S K++PA R+ AP + + G P A
Sbjct: 217 SVKPAQVKASSVSTKESPA--------RKAAPAPGKVGDVTPQVKGGALPPA-------- 260
Query: 2817 DDKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPV 2876
K K P + S E+ + S + P +V+ E++L V + + T P
Sbjct: 261 --KRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPA 318
Query: 2877 GEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELAN 2936
GK + S+ + P+E ++
Sbjct: 319 PPGKA---------------GAVASQTKAGKPEEDSE----------------------- 340
Query: 2937 GAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPF 2996
S+ +++ DS + ++ +L+A V + P K +S + P P
Sbjct: 341 -------SSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAK-ESPRKGAAPAPPG 392
Query: 2997 KRGGGKDGSVTGTKRLRCMPAPEE--IVEELPA-SKKQRVAPRARGKSSEPVVIMKRSLR 3053
K G + G + + EE EE PA +K AP+ R S+ K S R
Sbjct: 393 KTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAP----AKESPR 448
Query: 3054 TSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAE 3113
A P KT ++Q + +++ +E+ ++ LA
Sbjct: 449 KGAAPAPP--------RKTGPAAAQVQVG---------KQEEDSRSSSEESDSDREALA- 490
Query: 3114 RIEINRNEKKPMKTSPEMDI-----QNPDDGARKPIPRDKV---TENKRCLRSARQNESS 3165
+N + KP+ SP++ P P+P KV T + + + +ESS
Sbjct: 491 --AMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESS 548
Query: 3166 QPKVAEESGGQKSAKVLMQNQKGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVTRS 3225
+ ++ S G+ V +K G + K S PA + V
Sbjct: 549 SEESSDSSDGEVPTAVAPAQEKSLGN--------ILQAKPTSSPAKGPPQKAGPVAVQVK 600
Query: 3226 VKRCAENPKKAEDN 3239
++ +N + +E++
Sbjct: 601 AEKPMDNSESSEES 614
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 65.5 bits (158), Expect = 8e-10
Identities = 314/1536 (20%), Positives = 534/1536 (34%), Gaps = 276/1536 (17%)
Query: 856 TKTSDTETEPSKTVSTANRSGRSTEFRN--------IQKLPVESKSEETN--TEIVECIL 905
TK S+++ E + + + TE + ++PV + + + +E+ + ++
Sbjct: 1456 TKESESDQEQEEEIDMTSEKNDETESTETSVLKSHLVNEVPVLASPDLLSEVSEMKQDLI 1515
Query: 906 KRGQKATLLQQRREG--EMKEI-----ERPFETYKENIELKENDEKMKAMKRSRTWGQKC 958
K T + G ++KE+ E P E ++ +KE+ EK+ + RS T +
Sbjct: 1516 KMTAILTTDVSDKAGSIKVKELVKAAEEEPGEPFEIVERVKEDLEKVNEILRSGTCTRDE 1575
Query: 959 APMSDLTDLKSLPDTELMK------DTARGQNLLQTQDH----AKAPKSEKGKITKMPCQ 1008
+ + + L + E + + AR + L+ ++ + K KGK+ K
Sbjct: 1576 SSVQSSRSERGLVEEEWVIVSDEEIEEARQKAPLEITEYPCVEVRIDKEIKGKVEKDSTG 1635
Query: 1009 SLQ--PEPINTPTHT-KQQLKASLGKVGVKEELLAVGKFTRTSGE---------TTHTHR 1056
+ + +NT K+QL+ K G K E LAVG+ + G+ T H+
Sbjct: 1636 LVNYLTDDLNTCVPLPKEQLQTVQDKAGKKCEALAVGRSSEKEGKDIPPDETQSTQKQHK 1695
Query: 1057 EPAGDGKSI-RTFKESPKQILDPAARVTGMKKWPRTPKEEAQSLEDLAGFKELFQTPGPS 1115
G K + R KE KQ K+ E L+ + + L + PG +
Sbjct: 1696 PSLGIKKPVRRKLKEKQKQ-----------KEEGLQASAEKAELKKGSSEESLGEDPGLA 1744
Query: 1116 EESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLALRKL-------TP 1168
E + K T P +TP + + ++L+K VE+E KL
Sbjct: 1745 PEPLPTVKATS-------PLIEETPIGSIKDKVKALQKR-VEDEQKGRSKLPIRVKGKED 1796
Query: 1169 SAGKAMLTPKPAGGDE-KDIKAFMGTPVQKLDLAGTLPGS-KRQLQTPKEKAQALEDLAG 1226
K P PA K + G+P K + TL S K + P + E +
Sbjct: 1797 VPKKTTHRPHPAASPSLKSERHAPGSPSPKTERHSTLSSSAKTERHPPVSPSSKTEKHSP 1856
Query: 1227 FKELFQTPGH--------TEELVAAGKTTKIPCDSPQSD-------PVDTPTSTKQRPK- 1270
+T H TE+ +TK SP S PV T +RP
Sbjct: 1857 VSPSAKTERHSPASSSSKTEKHSPVSPSTKTERHSPVSSTKTERHPPVSPSGKTDKRPPV 1916
Query: 1271 ----RSIRKADVE-GELLACRNLMPSAGKAMHTPKPSVGE-EKDIIIFVGTPVQKLDLTE 1324
R+ + V G + PS H P + G+ EK + PV TE
Sbjct: 1917 SPSGRTEKHPPVSPGRTEKRLPVSPSGRTDKHQPVSTAGKTEKHL------PVSPSGKTE 1970
Query: 1325 NLTGSKRRPQTPKEEAQALEDLTGFKELF------QTPGHTEEAVAAGKTTKMPCESSPP 1378
K+ P +P + + +E+ +EL Q P + + K+ K + P
Sbjct: 1971 -----KQPPVSPTSKTERIEETMSVRELMKAFQSGQDPSKHKTGLFEHKSAK---QKQPQ 2022
Query: 1379 ESADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETA 1438
E + P L +R+ QK + K Q T + G SI +E A
Sbjct: 2023 EKGKVRVEKEKGP--ILTQREAQKTENQTIKRGQRLPVTGTAESKRGVRVSSIGVKKEDA 2080
Query: 1439 ---KQKL------DPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKT 1489
K+K+ +P SV + H +++ + + D G +L +P D+ T+ + +
Sbjct: 2081 AGGKEKVLSHKIPEPVQSVPEEESHRESEVPKEKMADEQGDMDLQISP---DRKTSTDFS 2137
Query: 1490 TKIACRSQPDPVDTPTSSKPQSKRSLRKVD---------------VEEEFFALRKRTPSA 1534
I + + +++++ +D +++EF A
Sbjct: 2138 EVIKQELEDNDKYQQFRLSEETEKAQLHLDQVLTSPFNTTFPLDYMKDEFLPALSLQSGA 2197
Query: 1535 --GKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGFK 1592
G + V+G GTP +E + +TP+ ++L K
Sbjct: 2198 LDGSSESLKNEGVAGSPCGSLMEGTPQIS---SEESYKHEGLAETPETSPESLS--FSPK 2252
Query: 1593 ELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKL 1652
+ + G T+ES + T ++ + P S+ R T E
Sbjct: 2253 KSEEQTGETKESTKTETTTEIRSEKEHPTTKDITGGSEERGATVTEDSETSTESFQKEAT 2312
Query: 1653 TQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGKSEVPEDLAG 1712
+ +T+ + S+ E+P + + AA G +R + K+
Sbjct: 2313 LGSPKDTSPKRQDDCTGSCSVALAKETPTGLTEEAACDEG-QRTFGSSAHKT-------- 2363
Query: 1713 FIELFQTPSHTKESMTNEKTTKVSYRASQPDLVDTPTSSKPQ-------------PKR-- 1757
QT S +ES TK DT T SKPQ P R
Sbjct: 2364 -----QTDSEVQESTATSDETKALPLPEASVKTDTGTESKPQGVIRSPQGLELALPSRDS 2418
Query: 1758 SLRKADTEEEFLAFRKQTPSAGKAMH------TP---KPAVGEEKDINTFL-GTPVQKLD 1807
+ A ++ K + A + TP +P+ +E L +PV+
Sbjct: 2419 EVLSAVADDSLAVSHKDSLEASPVLEDNSSHKTPDSLEPSPLKESPCRDSLESSPVEPKM 2478
Query: 1808 QPGNLPGSNRRLQTRKEKAQALEELTGFR-ELFQTPCTDNPTTDEKTTKKILCKSPQSDP 1866
+ G P S+ L K + L E+ R L + P D D+ + L +S P
Sbjct: 2479 KAGIFP-SHFPLPAAVAKTELLTEVASVRSRLLRDP--DGSAEDDSLEQTSLMESSGKSP 2535
Query: 1867 --ADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAV----GEEKDINTF 1920
DTP++ + + + K DV TPK AV EE D
Sbjct: 2536 LSPDTPSSEEVSYEVTPKTTDVS------------------TPKPAVIHECAEEDDSEN- 2576
Query: 1921 VGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQ----------TPGHTEES 1970
G K+R +E K + + F EL Q P E S
Sbjct: 2577 ---------------GEKKRFTPEEEMFKMVTKIKMFDELEQEAKQKRDYKKEPKQEESS 2621
Query: 1971 MTDDKITEVSCKSPQPD-----------PV-------KTPTSSKQRLKISLGKVGVKEEV 2012
+ D + S +P PV K +SS+ +++ K G +
Sbjct: 2622 SSSDPDADCSVDVDEPKHTGSGEDESGVPVLVTSESRKVSSSSESEPELAQLKKGADSGL 2681
Query: 2013 LPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQS 2072
LP + + ++ + ++ +KQ N T E P +EE S
Sbjct: 2682 LPEPVIRVQPPSPLPSSMDSNSSPEEVQFQPVVSKQYTFKMNEDTQEE--PGKSEEEKDS 2739
Query: 2073 LEDLAGFKELFQTPDHT---EESTTDDKTTKI----ACKSPPPESMDTPTSTRRRPKTPL 2125
LA + T ++ D KI C++ P S P S+ ++P
Sbjct: 2740 ESHLAEDRHAVSTEAEDRSYDKLNRDTDQPKICDGHGCEAMSPSSSAAPVSSGL--QSPT 2797
Query: 2126 GKRDIVEELSALKQ--LTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRT 2183
G D+ E+ K+ Q TH G+E ++V R + Q P+ S + S P
Sbjct: 2798 GD-DVDEQPVIYKESLALQGTHEKDTEGEE---LDVSRAESPQADCPSESFSSSSSLPHC 2853
Query: 2184 PKGKAQPL-EDLAGLKELFQTPICTDKPTTHEKTTK 2218
+ + L ED++ + +T + T T E K
Sbjct: 2854 LVSEGKELDEDISATSSIQKTEV-TKTDETFENLPK 2888
Score = 47.8 bits (112), Expect = 2e-04
Identities = 201/995 (20%), Positives = 334/995 (33%), Gaps = 213/995 (21%)
Query: 2326 PGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQR-----PKRNLRKADVEEEFLALRKRT 2380
PG+ P T+ +T + + P +P+S ++ P + K +
Sbjct: 1820 PGSPSPKTERHSTLSSSAKTERHPPVSPSSKTEKHSPVSPSAKTERHSPASSSSKTEKHS 1879
Query: 2381 PSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGF 2440
P + VS K +P K D KR P +P + E
Sbjct: 1880 PVSPSTKTERHSPVSSTKTERHPPVSPSGKTD--------KRPPVSPSGRTE-------- 1923
Query: 2441 KELFQTPGHTEESMT------DDKITEVSCKSPQPESFKTSRSSKQRLKIPLV---KVDM 2491
K +PG TE+ + DK VS + S S K + P+ K +
Sbjct: 1924 KHPPVSPGRTEKRLPVSPSGRTDKHQPVSTAGKTEKHLPVSPSGKTEKQPPVSPTSKTER 1983
Query: 2492 KEEPLAVSKLTRT--SGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTR 2549
EE ++V +L + SG+ H + KS K ++ P++ + ++R
Sbjct: 1984 IEETMSVRELMKAFQSGQDPSKHKTGLFEHKSAK--QKQPQE-----------KGKVRVE 2030
Query: 2550 KEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPR 2609
KEK L E+ TI + ++P +T TA S
Sbjct: 2031 KEKGPILTQ---------REAQKTENQTIKRGQRLP-------VTGTAES---------- 2064
Query: 2610 KEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAP 2669
+R + S S KE A+G + KVL + + V EE S R P
Sbjct: 2065 ----------KRGVRVS--SIGVKKEDAAGGKE-KVLSHKIPEPVQSVPEEESHRESEVP 2111
Query: 2670 KEK--------------------------AQPLEDLAGFTE--LSETSG----HTQESLT 2697
KEK Q LED + + LSE + H + LT
Sbjct: 2112 KEKMADEQGDMDLQISPDRKTSTDFSEVIKQELEDNDKYQQFRLSEETEKAQLHLDQVLT 2171
Query: 2698 AGKATKIPCESPPLEVVDTTASTKRHLRTRVQKVQ---VKEEPSAVKFTQTSGETTDADK 2754
+ T P + E + + L + ++ V P T +++
Sbjct: 2172 SPFNTTFPLDYMKDEFLPALSLQSGALDGSSESLKNEGVAGSPCGSLMEGTPQISSEESY 2231
Query: 2755 EPAGEDKGIKALKESAKQTPAPAASVTGSRRRP---------RAPRESAQAIEDLAGFKD 2805
+ G + + ES +P + TG + R+ +E + G ++
Sbjct: 2232 KHEGLAETPETSPESLSFSPKKSEEQTGETKESTKTETTTEIRSEKEHPTTKDITGGSEE 2291
Query: 2806 PAAGHTEESMTD------DKTTKIPCKSSPELEDTATSS------KRRPRTRAQKVEVKE 2853
A TE+S T + T P +SP+ +D T S K P ++ E
Sbjct: 2292 RGATVTEDSETSTESFQKEATLGSPKDTSPKRQDDCTGSCSVALAKETPTGLTEEAACDE 2351
Query: 2854 ELLAVGKLTQTSGETTHTD---KEPVGEGKGTKAFKQP-AKRKLDAEDVIGSRRQPRAPK 2909
G +S T TD +E TKA P A K D G+ +P+
Sbjct: 2352 GQRTFG----SSAHKTQTDSEVQESTATSDETKALPLPEASVKTDT----GTESKPQGVI 2403
Query: 2910 EKAQPLE-DLASFQELSQTPGHTEELANGAADSFTSAP-------KQTPDSGKPLKISRR 2961
Q LE L S + + LA DS ++P +TPDS +P +
Sbjct: 2404 RSPQGLELALPSRDSEVLSAVADDSLAVSHKDSLEASPVLEDNSSHKTPDSLEPSPL--- 2460
Query: 2962 VLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDGSVT--GTKRLRCMPAPE 3019
K P D + + PV+ + K+ P K +T + R R + P+
Sbjct: 2461 -----KESPCRDSLES-SPVEPKMKAGIFPSHFPLPAAVAKTELLTEVASVRSRLLRDPD 2514
Query: 3020 EIVEE--------LPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEPAEELNSNDMK 3071
E+ + +S K ++P + ++ S + E D
Sbjct: 2515 GSAEDDSLEQTSLMESSGKSPLSPDTPSSEEVSYEVTPKTTDVSTPKPAVIHECAEEDDS 2574
Query: 3072 TNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKKPMKTSPEM 3131
N E+ + PE + + ++ + E EQ+ + R+ KK K
Sbjct: 2575 ENGEKKRF---TPEEEMFKMVTKIKMFDELEQEAKQ----------KRDYKKEPKQEESS 2621
Query: 3132 DIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVA-----EESGGQKSAKVLMQNQ 3186
+PD + K T + ++ES P + + S +S L Q +
Sbjct: 2622 SSSDPDADCSVDVDEPKHT-------GSGEDESGVPVLVTSESRKVSSSSESEPELAQLK 2674
Query: 3187 KGKGEAGNSDSMCLRSRKTKSQPAA---STLESKS 3218
KG +DS L + QP + S+++S S
Sbjct: 2675 KG------ADSGLLPEPVIRVQPPSPLPSSMDSNS 2703
Score = 44.3 bits (103), Expect = 0.002
Identities = 241/1251 (19%), Positives = 418/1251 (33%), Gaps = 199/1251 (15%)
Query: 2066 PKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPL 2125
PKE+ Q+++D AG K E+ ++++ K PP D ST+++ K L
Sbjct: 1651 PKEQLQTVQDKAGKKC---------EALAVGRSSEKEGKDIPP---DETQSTQKQHKPSL 1698
Query: 2126 GKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPK 2185
G + V KQ +++G+ E A+ K + G P
Sbjct: 1699 GIKKPVRRKLKEKQK-----------QKEEGLQASAEKAELKKGSSEESLGED-----PG 1742
Query: 2186 GKAQPLEDLAGLKELFQ-TPICT--DKPTTHEKT--------TKIACRSPQPDPVGTPTI 2234
+PL + L + TPI + DK +K +K+ R + V T
Sbjct: 1743 LAPEPLPTVKATSPLIEETPIGSIKDKVKALQKRVEDEQKGRSKLPIRVKGKEDVPKKTT 1802
Query: 2235 FKPQ-----SKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQK 2289
+P S +S R A R T S + P K K +P K
Sbjct: 1803 HRPHPAASPSLKSERHAPGSPSPKTERHSTLSSSAKTERHPPVSPSSKTEKHSPVSPSAK 1862
Query: 2290 LDLPGNLPGS----KRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSP 2345
+ S K P +P K + ++ K P + TD++
Sbjct: 1863 TERHSPASSSSKTEKHSPVSPSTKTERHSPVSSTKTERHPPVSPSGKTDKRP-------- 1914
Query: 2346 QPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTP-SAGKAMDTPKPAVSDEKNINTFV 2404
PV T++ P + + + KR P S D +P + K
Sbjct: 1915 ---PVSPSGRTEKHPPVSPGRTE---------KRLPVSPSGRTDKHQPVSTAGKTEKHLP 1962
Query: 2405 ETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELF------QTPGHTEESMTDDK 2458
+P K + K+ P +P K E +E+ + +EL Q P + + + K
Sbjct: 1963 VSPSGKTE--------KQPPVSPTSKTERIEETMSVRELMKAFQSGQDPSKHKTGLFEHK 2014
Query: 2459 ITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSK-----LTRTSGETTQTHT 2513
S K QP+ R K++ I + K E + + +T T+
Sbjct: 2015 ----SAKQKQPQEKGKVRVEKEKGPILTQREAQKTENQTIKRGQRLPVTGTAESKRGVRV 2070
Query: 2514 EPTGDSKSIKAF---KESPKQILDPAASVTG--SRRQLRTRKEKARALEDLVDFKELFSA 2568
G K A K +I +P SV S R+ KEK + +D +
Sbjct: 2071 SSIGVKKEDAAGGKEKVLSHKIPEPVQSVPEEESHRESEVPKEKMADEQGDMDLQISPDR 2130
Query: 2569 PGHTEESMTIDKNTKIPCKSPPPELTDTATS---------TKRCPKTRPRKEVKEELSAV 2619
T+ S I + + K L++ T T P +K+E
Sbjct: 2131 KTSTDFSEVIKQELEDNDKYQQFRLSEETEKAQLHLDQVLTSPFNTTFPLDYMKDEFLPA 2190
Query: 2620 ERLTQTS--GQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLE 2677
L + G S E +G +++ P EE + A + P
Sbjct: 2191 LSLQSGALDGSSESLKNEGVAGSPCGSLMEGT----PQISSEESYKHEGLAETPETSPES 2246
Query: 2678 DLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEP 2737
+ E +G T+ES T+I E D T ++ T V E
Sbjct: 2247 LSFSPKKSEEQTGETKESTKTETTTEIRSEKEHPTTKDITGGSEERGAT----VTEDSET 2302
Query: 2738 SAVKFTQTSGETTDADKEPAGEDKGIKALKES-AKQTPAPAASVTGSRRRPRAPRESAQA 2796
S F + + + D P +D + + AK+TP R SA
Sbjct: 2303 STESFQKEATLGSPKDTSPKRQDDCTGSCSVALAKETPTGLTEEAACDEGQRTFGSSAHK 2362
Query: 2797 IEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRA-QKVEV---K 2852
+ + ++ A T D+T +P + DT T SK + R+ Q +E+
Sbjct: 2363 TQTDSEVQESTA-------TSDETKALPLPEASVKTDTGTESKPQGVIRSPQGLELALPS 2415
Query: 2853 EELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKE-K 2911
+ + + S +H D L+A V+ + P +
Sbjct: 2416 RDSEVLSAVADDSLAVSHKD-------------------SLEASPVLEDNSSHKTPDSLE 2456
Query: 2912 AQPLEDLASFQELSQTPGHTEELANGAADSF--TSAPKQTPDSGKPLKISRRVLRAPKVE 2969
PL++ L +P + A F +A +T + + R+LR P
Sbjct: 2457 PSPLKESPCRDSLESSPVEPKMKAGIFPSHFPLPAAVAKTELLTEVASVRSRLLRDPDGS 2516
Query: 2970 PVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDGSVTGTKRLRCMPAPEEIV------- 3022
D + ++S KS PL ++ S T + + P+ V
Sbjct: 2517 AEDDSLEQTSLMESSGKS-----PLSPDTPSSEEVSYEVTPKTTDVSTPKPAVIHECAEE 2571
Query: 3023 EELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAK-----RIEPAEELNSN------DMK 3071
++ +K+R P + M L AK + EP +E +S+ D
Sbjct: 2572 DDSENGEKKRFTPEEEMFKMVTKIKMFDELEQEAKQKRDYKKEPKQEESSSSSDPDADCS 2631
Query: 3072 TNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKKPMKTSPEM 3131
+ +E K S + G+ + +++ + +E E ++ + + P +
Sbjct: 2632 VDVDEPKHTGSGEDESGVPVLVTSESRKVSSSSESE----PELAQLKKGADSGLLPEPVI 2687
Query: 3132 DIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKVLMQNQKGKGE 3191
+Q P P+P + S+ + QP V+++ + + Q + GK E
Sbjct: 2688 RVQPP-----SPLPSSMDS------NSSPEEVQFQPVVSKQYTFKMNEDT--QEEPGKSE 2734
Query: 3192 AGNSDSMCLRSRKTKSQPAAST-LESKSVQRVTRSVKRCAENPKKAEDNVC 3241
DS S + + A ST E +S ++ R + PK + + C
Sbjct: 2735 E-EKDS---ESHLAEDRHAVSTEAEDRSYDKLNRD----TDQPKICDGHGC 2777
Score = 38.1 bits (87), Expect = 0.14
Identities = 363/1867 (19%), Positives = 657/1867 (35%), Gaps = 309/1867 (16%)
Query: 1572 KRRL-QTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKV----ACKSSQPDPDKNP 1626
+R+L + K+K + L+ A EL +G +EES+ D K++ P ++ P
Sbjct: 1705 RRKLKEKQKQKEEGLQASAEKAEL--KKGSSEESLGEDPGLAPEPLPTVKATSPLIEETP 1762
Query: 1627 ASSKRRLKTSLGKVGVKEELLAVGKLT-------QTSGETTHT-HTEPTGDGKSMKAFME 1678
S + +L K V++E KL +TTH H + KS +
Sbjct: 1763 IGSIKDKVKALQK-RVEDEQKGRSKLPIRVKGKEDVPKKTTHRPHPAASPSLKSERHAPG 1821
Query: 1679 SPKQILDSAASLTGS-KRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTN--EKTTKV 1735
SP + ++L+ S K + P S E + +T H+ S ++ EK + V
Sbjct: 1822 SPSPKTERHSTLSSSAKTERHPPVSPSSKTEKHSPVSPSAKTERHSPASSSSKTEKHSPV 1881
Query: 1736 S--YRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEK 1793
S + + V + + + P K D +PS H P EK
Sbjct: 1882 SPSTKTERHSPVSSTKTERHPPVSPSGKTDKRPPV------SPSGRTEKHPPVSPGRTEK 1935
Query: 1794 DINTFLGTPVQKLD--QPGNLPGSNRRL-------QTRKE-------KAQALEELTGFRE 1837
+ +P + D QP + G + +T K+ K + +EE RE
Sbjct: 1936 RLPV---SPSGRTDKHQPVSTAGKTEKHLPVSPSGKTEKQPPVSPTSKTERIEETMSVRE 1992
Query: 1838 LFQTPCTDNPTTDEKTT----KKILCKSPQSDPADTPTNTKQRPKRSLKKAD-VEEEFLA 1892
L + + + KT K K PQ + ++ P + ++A E + +
Sbjct: 1993 LMKAFQSGQDPSKHKTGLFEHKSAKQKQPQ-EKGKVRVEKEKGPILTQREAQKTENQTIK 2051
Query: 1893 FRKLTPSAGKA------------MHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRR 1940
+ P G A + AA G+EK ++ + PV+ + S R
Sbjct: 2052 RGQRLPVTGTAESKRGVRVSSIGVKKEDAAGGKEKVLSHKIPEPVQSVPE----EESHRE 2107
Query: 1941 PQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLK 2000
+ PKEK + D G +L +P + + I + + + + + ++ +
Sbjct: 2108 SEVPKEK---MADEQGDMDLQISPDRKTSTDFSEVIKQELEDNDKYQQFRL-SEETEKAQ 2163
Query: 2001 ISLGKV------------GVKEEVLPVGKLTQTSGK---TTQTHRETAGDGKSIKAFKES 2045
+ L +V +K+E LP L+ SG ++++ + G + E
Sbjct: 2164 LHLDQVLTSPFNTTFPLDYMKDEFLPA--LSLQSGALDGSSESLKNEGVAGSPCGSLMEG 2221
Query: 2046 AKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKS 2105
Q+ +Y E TP+ +SL K+ + T+EST + TT+I +
Sbjct: 2222 TPQISSEESYKH--EGLAETPETSPESLSFSP--KKSEEQTGETKESTKTETTTEIRSEK 2277
Query: 2106 PPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDK-----GINVF 2160
P + D + R T + E S K+ T + D P +D + +
Sbjct: 2278 EHPTTKDITGGSEERGATVTEDSETSTE-SFQKEATLGSPKDTSPKRQDDCTGSCSVALA 2336
Query: 2161 RETAKQKLDPAASVTGS--------KRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTT 2212
+ET + AA G K Q + ++ D L + + TD T
Sbjct: 2337 KETPTGLTEEAACDEGQRTFGSSAHKTQTDSEVQESTATSDETKALPLPEASVKTDTGT- 2395
Query: 2213 HEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTP----------SV 2262
E + RSPQ + P S+ S + V ++SLA+ + S
Sbjct: 2396 -ESKPQGVIRSPQGLELALP------SRDSEVLSAVADDSLAVSHKDSLEASPVLEDNSS 2448
Query: 2263 GKAMDTPKPAGGDEKDMK-AFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFK- 2320
K D+ +P+ E + + +PV+ G P P K + L ++A +
Sbjct: 2449 HKTPDSLEPSPLKESPCRDSLESSPVEPKMKAGIFPSHFPLP-AAVAKTELLTEVASVRS 2507
Query: 2321 ELFQTP-GTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKR 2379
L + P G+ + + E+T+ + P DTP+S + + + DV
Sbjct: 2508 RLLRDPDGSAEDDSLEQTSLMESSGKSPLSPDTPSSEEVSYEVTPKTTDV---------- 2557
Query: 2380 TPSAGKAMDTPKPAV-------SDEKNINTFVETPVQKL-DLLGNLPGSKRQPQTPKEKA 2431
TPKPAV D +N TP +++ ++ + Q K+K
Sbjct: 2558 --------STPKPAVIHECAEEDDSENGEKKRFTPEEEMFKMVTKIKMFDELEQEAKQK- 2608
Query: 2432 EALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPL----- 2486
++ + P E S + D + S +P K + S + +P+
Sbjct: 2609 ---------RDYKKEPKQEESSSSSDPDADCSVDVDEP---KHTGSGEDESGVPVLVTSE 2656
Query: 2487 ---VKVDMKEEP-LAVSKLTRTSGETTQ--THTEPTGDSKSIKAFKESPKQI-LDPAASV 2539
V + EP LA K SG + +P S SP+++ P S
Sbjct: 2657 SRKVSSSSESEPELAQLKKGADSGLLPEPVIRVQPPSPLPSSMDSNSSPEEVQFQPVVSK 2716
Query: 2540 TGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKN-TKIPCKSPPPELTD--- 2595
+ + +E+ E+ D + + H + D++ K+ + P++ D
Sbjct: 2717 QYTFKMNEDTQEEPGKSEEEKDSESHLAEDRHAVSTEAEDRSYDKLNRDTDQPKICDGHG 2776
Query: 2596 ----TATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAK 2651
+ +S+ + + +++ + + S TH++ G+E + V + +
Sbjct: 2777 CEAMSPSSSAAPVSSGLQSPTGDDVDEQPVIYKESLALQGTHEKDTEGEE-LDVSRAESP 2835
Query: 2652 KKPNPVEE-EPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKAT--KIPCES 2708
+ P E S P + + L++ ++S TS + +T T +P +
Sbjct: 2836 QADCPSESFSSSSSLPHCLVSEGKELDE-----DISATSSIQKTEVTKTDETFENLPKDC 2890
Query: 2709 PPLEVVDTTASTKRHLRTRVQKVQVKEE-------------PSAVKFTQTSGET-TDADK 2754
P + TT + + + V + +E PS F+ +T TDA+
Sbjct: 2891 PSQDSSITTQTDRFSMDVPVSDLAENDEIYDPQITSPYENVPSQSFFSSEESKTQTDANH 2950
Query: 2755 EPAGEDKGIKALK-ESAKQTPAPAASVTG------SRRRPRAPRESAQAIEDLAGFKDPA 2807
+ + ++ S + A+S +G S + + +Q L + +
Sbjct: 2951 TTSFHSSEVYSVTITSPVEDVVVASSSSGTVLSKESNFEGQDIKMESQQESTLWEMQSDS 3010
Query: 2808 AGHTEESMTDDKTTKIPCKSSPEL-----EDTATSSKRRPRTRAQKVEVKEEL-----LA 2857
+ E TT + + S + D+ + S+ R A + VKEE L
Sbjct: 3011 VSSSFEPTMSATTTVVGEQISKVIITKTDVDSDSWSEIREDDEAFEARVKEEEQKIFGLM 3070
Query: 2858 VGKLTQTSGETTHTDKEPVGEGKGT-----------KAFKQPAKRKLD------------ 2894
V + +Q + T + P EG T K F+ +D
Sbjct: 3071 VDRQSQGTTPDTTPARTPTEEGTPTSEQNPFLFQEGKLFEMTRSGAIDMTKRSYADESFH 3130
Query: 2895 --------AEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAP 2946
E+ + + A PLE A LS++ ++ A+ D +
Sbjct: 3131 FFQIGQESREETLSEDVKEGATGADPLPLETSAESLALSESKETVDDEADLLPDDVSEEV 3190
Query: 2947 KQTPDSGKPLKISRRVLRAPKVEPVGDVVS--TRDPVKSQSKSNTSLPPLPFKRGGGKDG 3004
++ P S L S+ + A P + VS T+D Q+ +PPL
Sbjct: 3191 EEIPASDAQLN-SQMGISASTETPTKEAVSVGTKDLPTVQT---GDIPPL---------- 3236
Query: 3005 SVTGTKRLRCMPAPEEIVE-ELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEPAE 3063
+G K++ C + E V+ +L S R RG S P + P E
Sbjct: 3237 --SGVKQISCPDSSEPAVQVQLDFSTLTRSVYSDRGDDS-PDSSPEEQKSVIEIPTAPME 3293
Query: 3064 ELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKK 3123
+ + K+ + S P E E ++E F+ + E +E K
Sbjct: 3294 NVPFTESKSKIPVRTMPTSTP----------APPSAEYESSVSEDFLSSVDEENKADEAK 3343
Query: 3124 PMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKVLM 3183
P P +P +V + L + S Q VA + GQ A +
Sbjct: 3344 PKSKLP------------VKVPLQRVEQQLSDL-----DTSVQKTVAPQ--GQDMASIAP 3384
Query: 3184 QNQ-KGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVTRSVKRCAENPKKAEDNVCV 3242
N+ K + +A + DS KT+S T + + + + A PK + V
Sbjct: 3385 DNRSKSESDASSLDSKTKCPVKTRSYTETETESRERAEELELESEEGATRPKILTSRLPV 3444
Query: 3243 KKIRTRS 3249
K T S
Sbjct: 3445 KSRSTTS 3451
Score = 37.7 bits (86), Expect = 0.19
Identities = 102/500 (20%), Positives = 173/500 (34%), Gaps = 76/500 (15%)
Query: 2790 PRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKV 2849
P+E Q ++D AG K A S + K S + + + ++P R K
Sbjct: 1651 PKEQLQTVQDKAGKKCEALAVGRSSEKEGKDIPPDETQSTQKQHKPSLGIKKPVRRKLKE 1710
Query: 2850 EVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQP---AKRKLDAEDVIGSRR--- 2903
+ K++ + + + + +E +GE G P A L E IGS +
Sbjct: 1711 KQKQKEEGLQASAEKAELKKGSSEESLGEDPGLAPEPLPTVKATSPLIEETPIGSIKDKV 1770
Query: 2904 ---QPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKP----- 2955
Q R E+ + + P T + AA + + P S P
Sbjct: 1771 KALQKRVEDEQKGRSKLPIRVKGKEDVPKKTTHRPHPAASPSLKSERHAPGSPSPKTERH 1830
Query: 2956 --LKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDGSVTGTKRLR 3013
L S + R P V P PV +K+ P + TK R
Sbjct: 1831 STLSSSAKTERHPPVSP-SSKTEKHSPVSPSAKTERHSPASSSSKTEKHSPVSPSTKTER 1889
Query: 3014 CMPAPEEIVEELP-------ASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEPAEELN 3066
P E P K+ V+P R + PV S + KR+ +
Sbjct: 1890 HSPVSSTKTERHPPVSPSGKTDKRPPVSPSGRTEKHPPV-----SPGRTEKRLPVSPSGR 1944
Query: 3067 SNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKKPMK 3126
++ + K + +P + KTE + ++ ERIE + ++ MK
Sbjct: 1945 TDKHQPVSTAGKTEKHLPVSP--------SGKTEKQPPVSPT-SKTERIEETMSVRELMK 1995
Query: 3127 TSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKVLMQNQ 3186
Q+ D ++ +K L + + QP Q+ KV ++ +
Sbjct: 1996 A-----FQSGQDPSK----------HKTGLFEHKSAKQKQP--------QEKGKVRVEKE 2032
Query: 3187 KG----KGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVTRSVKRCAENPKKAEDNVCV 3242
KG + EA +++ + ++ + P T ESK RV+ S+ E+ ++ V
Sbjct: 2033 KGPILTQREAQKTENQTI--KRGQRLPVTGTAESKRGVRVS-SIGVKKEDAAGGKEKVLS 2089
Query: 3243 KKI--------RTRSHRDSE 3254
KI SHR+SE
Sbjct: 2090 HKIPEPVQSVPEEESHRESE 2109
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 65.1 bits (157), Expect = 1e-09
Identities = 219/1039 (21%), Positives = 371/1039 (35%), Gaps = 193/1039 (18%)
Query: 1714 IELFQTPSHTKESMTNE------KTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEE 1767
++ + P T++ +T + K TK+ RA + + ++KP P +S+RK EE
Sbjct: 508 LDFLKQPLATQKDLTGQVPTPVVKQTKLKQRADSRESLKP--AAKPLPSKSVRKESKEE- 564
Query: 1768 FLAFRKQTPSAGKAMHTPKPA---------VGEEKDINTFLGTPVQKLDQPGNLPGSNRR 1818
TP K H KP V ++K I T V + + P S +
Sbjct: 565 -------TPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPSPVK 617
Query: 1819 LQTRKEKA-----QALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNT 1873
+ +++A +A +E T +E P D EK K++ K + TP
Sbjct: 618 AEVAEKQATDVKPKAAKEKTVKKETKVKP-EDKKEEKEKPKKEVAKKEDK-----TPIKK 671
Query: 1874 KQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAV------GEEKDINTFVGTPVEK 1927
+++PK+ K +V++E K P TP V E+K++ P ++
Sbjct: 672 EEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKE 731
Query: 1928 LDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQPD 1987
+ LP ++ TP +AK L + P EES+ D + K
Sbjct: 732 IK---KLPKDAKKSSTPLSEAKKPAALKP-----KVP-KKEESVKKDSVAAGKPK----- 777
Query: 1988 PVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGK--SIKAFKES 2045
K ++K+ + K G E + T G TT AG K +
Sbjct: 778 -------EKGKIKV-IKKEGKAAEAVAAAVGT---GATTAAVMAAAGIAAIGPAKELEAE 826
Query: 2046 AKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEES--------TTDDK 2097
M P + E EE +D+ EL + + +E+ + +
Sbjct: 827 RSLMSSPEDLTKDFE---ELKAEEVDVTKDIKPQLELIEDEEKLKETEPVEAYVIQKERE 883
Query: 2098 TTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGI 2157
TK +S P E + T +TP EEL +++ D + ED+G
Sbjct: 884 VTKGPAES-PDEGITTTEGEGECEQTP-------EELEPVEK----QGVDDIEKFEDEGA 931
Query: 2158 NVFRETAKQKLDPAASVTGSKRQPR--------TPKGKAQPLEDLAGLKELFQTPICTDK 2209
F E+++ + T +P K P ED K I
Sbjct: 932 G-FEESSETGDYEEKAETEEAEEPEEDGEEHVCVSASKHSPTEDEESAKAEADAYI---- 986
Query: 2210 PTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGK----- 2264
EK +A + + I K ++++S +AD E+++ R+ K
Sbjct: 987 ---REKRESVASGDDRAEEDMDEAIEKGEAEQSEEEADEEDKAEDAREEEYEPEKMEAED 1043
Query: 2265 ----AMDTPKPAGGDEKDMKAFMGTPVQKL--DLPGNLPGSKRWPQTPKEKAQALEDLAG 2318
+D AGG E + F+ TP ++L PG P S +T +++ E A
Sbjct: 1044 YVMAVVDKAAEAGGAE-EQYGFLTTPTKQLGAQSPGREPASSIHDETLPGGSES-EATAS 1101
Query: 2319 FKELFQTPGTDKPTTDEKTTKIACKSPQPDPVD---TPASTKQRPKRNLRKADVEEEFLA 2375
+E + + T T S +P P+D TP N +EF+
Sbjct: 1102 DEENREDQPEEFTATSGYTQSTIEISSEPTPMDEMSTPRDVMSDETNNEETESPSQEFVN 1161
Query: 2376 LRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLG----NLPGSKRQPQTPKEK- 2430
+ K S + + KPA D +N F E K D N S P + E+
Sbjct: 1162 ITKYESSL-YSQEYSKPA--DVTPLNGFSEG--SKTDATDGKDYNASASTISPPSSMEED 1216
Query: 2431 ---AEALEDLVGFKELFQTPGHTEESMTDDKITEVS-CKSPQPESFKTSRSSKQRLKIPL 2486
AL D + T ++S++ +VS KSP S K L
Sbjct: 1217 KFSRSALRDAYCSEVKASTTLDIKDSISAVSSEKVSPSKSPSLSPSPPSPLEKTPLGERS 1276
Query: 2487 VKVDMKEEPLAVS---KLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSR 2543
V + + VS ++ S E TQ E S K +++ P+ SVTGS
Sbjct: 1277 VNFSLTPNEIKVSAEAEVAPVSPEVTQEVVEEHCASPEDKTL-----EVVSPSQSVTGS- 1330
Query: 2544 RQLRTRKEKARALEDLVDFKELFSAPGHTE--ESMTIDKNTKIPCK--SPPP------EL 2593
GHT +S T +K++ +P + PP E
Sbjct: 1331 -------------------------AGHTPYYQSPTDEKSSHLPTEVIEKPPAVPVSFEF 1365
Query: 2594 TDTATSTKRCPKTRPRKEVKEELSAVERL-----------TQTSGQSTHTHKEPASGDEG 2642
+D +R + + V + S +E++ ++++ +S + + ASG
Sbjct: 1366 SDAKDENERASVSPMDEPVPDSESPIEKVLSPLRSPPLIGSESAYESFLSADDKASGRGA 1425
Query: 2643 IKVLKQRAKKKPNPVEEEP 2661
++++ K+ +P + P
Sbjct: 1426 ESPFEEKSGKQGSPDQVSP 1444
Score = 60.5 bits (145), Expect = 3e-08
Identities = 168/874 (19%), Positives = 306/874 (35%), Gaps = 131/874 (14%)
Query: 2191 LEDLAGLKEL--FQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKADV 2248
LE L LK L + P+ T K T + T + ++ + KP +K L V
Sbjct: 499 LEGLEKLKHLDFLKQPLATQKDLTGQVPTPVVKQTKLKQRADSRESLKPAAK-PLPSKSV 557
Query: 2249 EEESLALRKRTPSVGKAMDTPKPAGGDEKD---------MKAFMGTPVQKLDLPGNLPGS 2299
+ES ++ TP V K KP + K+ +K V + ++P S
Sbjct: 558 RKES---KEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEEPS 614
Query: 2300 KRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQR 2359
+ +++A ++ A ++ + KP ++ + K TP +++
Sbjct: 615 PVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEK 674
Query: 2360 PKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDE------KNINTFVETPVQKLDL 2413
PK+ K +V++E K+ P +TP V E K + + P +++
Sbjct: 675 PKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKK 734
Query: 2414 LGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFK 2473
L P + +K AL+ V K EES+ D +
Sbjct: 735 LPKDAKKSSTPLSEAKKPAALKPKVPKK---------EESVKKDSV-------------- 771
Query: 2474 TSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQIL 2533
+ K++ KI ++K + K + + +G TT G
Sbjct: 772 AAGKPKEKGKIKVIKKEGKAAEAVAAAV--GTGATTAAVMAAAG---------------- 813
Query: 2534 DPAASVTGSRRQLRTRKEKARALEDLV-DFKELFSAPGHTEESMTIDKNTKIPCKSPPPE 2592
+ G ++L + + EDL DF+EL E + + K+ K P E
Sbjct: 814 ---IAAIGPAKELEAERSLMSSPEDLTKDFEEL------KAEEVDVTKDIK-----PQLE 859
Query: 2593 LTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPA-SGDEGIKVLKQRAK 2651
L + K +T P V+ + ER K PA S DEGI + +
Sbjct: 860 LIEDEEKLK---ETEP---VEAYVIQKER---------EVTKGPAESPDEGITTTEGEGE 904
Query: 2652 KKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPL 2711
+ P E EP ++ EK + ++ AGF E SET + + KA E P
Sbjct: 905 CEQTPEELEPVEKQGVDDIEKFE--DEGAGFEESSETGDYEE------KAETEEAEEPEE 956
Query: 2712 EVVD-TTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESA 2770
+ + S +H T ++ E + ++ + S + D D+ D+ I+ +
Sbjct: 957 DGEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVASGD-DRAEEDMDEAIEKGEAEQ 1015
Query: 2771 KQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPA--AGHTEESMTDDKTTKIPCKSS 2828
+ A R E +A + + D A AG EE + ++
Sbjct: 1016 SEEEADEEDKAEDAREEEYEPEKMEAEDYVMAVVDKAAEAGGAEE--------QYGFLTT 1067
Query: 2829 PELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQ- 2887
P + A S R P + + +E L G ++ + ++ E T + Q
Sbjct: 1068 PTKQLGAQSPGREPAS-----SIHDETLPGGSESEATASDEENREDQPEEFTATSGYTQS 1122
Query: 2888 ---------PAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGA 2938
P DV+ + +Q ++ ++ + +++
Sbjct: 1123 TIEISSEPTPMDEMSTPRDVMSDETNNEETESPSQEFVNITKYESSLYSQEYSKPADVTP 1182
Query: 2939 ADSFTSAPKQTPDSGKPLKISRRVLRAPK--VEPVGDVVSTRDPVKSQSKSNTSLPPLPF 2996
+ F+ K GK S + P E + RD S+ K++T+L +
Sbjct: 1183 LNGFSEGSKTDATDGKDYNASASTISPPSSMEEDKFSRSALRDAYCSEVKASTTL-DIKD 1241
Query: 2997 KRGGGKDGSVTGTKRLRCMPAPEEIVEELPASKK 3030
V+ +K P+P +E+ P ++
Sbjct: 1242 SISAVSSEKVSPSKSPSLSPSPPSPLEKTPLGER 1275
Score = 60.5 bits (145), Expect = 3e-08
Identities = 354/1813 (19%), Positives = 622/1813 (34%), Gaps = 313/1813 (17%)
Query: 1184 EKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAA 1243
+KD+ + TPV K S+ L K A+ L + KE + ++
Sbjct: 518 QKDLTGQVPTPVVKQTKLKQRADSRESL---KPAAKPLPSKSVRKESKEETPEVTKVNHV 574
Query: 1244 GKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSV 1303
K K+ D P T+ +P S+ + +V + A K KP
Sbjct: 575 EKPPKVESKEKVMVKKDKPIKTETKP--SVTEKEVPSKEEPSPVKAEVAEKQATDVKPKA 632
Query: 1304 GEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDLTGFKELFQTPGHTEEAV 1363
+EK + K + K + PK+E ED T K+ + P E
Sbjct: 633 AKEKTV---------KKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKE-EKPKKEEVKK 682
Query: 1364 AAGKTTKMPCESSPPESA--DTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTD 1421
K K + P + +TP ++ EK++V+KE KK + +
Sbjct: 683 EVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKS 742
Query: 1422 KVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTD 1481
P E K A + +K + + + PK K K + ++ E V T
Sbjct: 743 STPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAVGTG 802
Query: 1482 KPT--------------------------THEKTTKIACRSQPDPVDTPTSSKPQSKRSL 1515
T + E TK + + VD KPQ L
Sbjct: 803 ATTAAVMAAAGIAAIGPAKELEAERSLMSSPEDLTKDFEELKAEEVDVTKDIKPQ----L 858
Query: 1516 RKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRL 1575
++ EE+ L++ P + + G +P + + TE G
Sbjct: 859 ELIEDEEK---LKETEPVEAYVIQKEREVTKGPAE------SPDEGITTTE---GEGECE 906
Query: 1576 QTPKE----KAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKR 1631
QTP+E + Q ++D+ F++ + G E S T D K + ++ +P+++
Sbjct: 907 QTPEELEPVEKQGVDDIEKFED--EGAGFEESSETGDYEEKAETEEAE-EPEED------ 957
Query: 1632 RLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASLT 1691
EE + V + + PT D +S KA E+ I + S+
Sbjct: 958 -----------GEEHVCV----------SASKHSPTEDEESAKA--EADAYIREKRESVA 994
Query: 1692 GSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQPDLVDTPTSS 1751
G ED+ IE + +E+ +K +P+
Sbjct: 995 ---------SGDDRAEEDMDEAIEKGEAEQSEEEADEEDKAEDAREEEYEPE-------- 1037
Query: 1752 KPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKL--DQP 1809
K + E+ +A + AG G E+ FL TP ++L P
Sbjct: 1038 ---------KMEAEDYVMAVVDKAAEAG----------GAEEQYG-FLTTPTKQLGAQSP 1077
Query: 1810 GNLPGSNRRLQT----RKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSD 1865
G P S+ +T + +A A +E + + T T ++T +I + D
Sbjct: 1078 GREPASSIHDETLPGGSESEATASDEENREDQPEEFTATSGYT---QSTIEISSEPTPMD 1134
Query: 1866 PADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTF-VGTP 1924
TP + + + +EF+ K S ++ A V +N F G+
Sbjct: 1135 EMSTPRDVMSDETNNEETESPSQEFVNITKYESSLYSQEYSKPADV---TPLNGFSEGSK 1191
Query: 1925 VEKLDLLG-NLPGSKRRPQTPKEKAK----ALEDLAGFKELFQTPGHTEESMTDDKITEV 1979
+ D N S P + E+ K AL D + T ++S++ +V
Sbjct: 1192 TDATDGKDYNASASTISPPSSMEEDKFSRSALRDAYCSEVKASTTLDIKDSISAVSSEKV 1251
Query: 1980 S-CKSPQ-----PDPVKTPTSSKQRLKISLG----KVGVKEEVLPVGKLTQTSGKTTQTH 2029
S KSP P P++ ++ + SL KV + EV PV + + + + H
Sbjct: 1252 SPSKSPSLSPSPPSPLEKTPLGERSVNFSLTPNEIKVSAEAEVAPVS--PEVTQEVVEEH 1309
Query: 2030 RETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHT 2089
+ D K+++ S G + ++P +E S ++ P
Sbjct: 1310 CASPED-KTLEVVSPS-----QSVTGSAGHTPYYQSPTDEKSSHLPTEVIEKPPAVPVSF 1363
Query: 2090 EESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKV 2149
E S D+ + A SP E + S + +PL ++ SA + DK
Sbjct: 1364 EFSDAKDENER-ASVSPMDEPVPDSESPIEKVLSPLRSPPLIGSESAYESFLSA--DDKA 1420
Query: 2150 PG-------DEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQ 2202
G +E G ++ + ++ P + +T + +GK+ D A +KE F
Sbjct: 1421 SGRGAESPFEEKSG----KQGSPDQVSPVSEMTSTSLYQDKQEGKS---TDFAPIKEDFG 1473
Query: 2203 TPICTD-------KPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLAL 2255
TD +P K+ SP V FK +K S+ + V ++S
Sbjct: 1474 QEKKTDDVEAMSSQPALALDERKLGDVSPTQIDVSQFGSFKEDTKMSISEGTVSDKS--- 1530
Query: 2256 RKRTP-SVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALE 2314
TP G A DT G A + T ++ S + +
Sbjct: 1531 --ATPVDEGVAEDTYSHMEGVASVSTASVATSSFPEPTTDDVSPSLHAEVGSPHSTEVDD 1588
Query: 2315 DLAGFKELFQTPGTDKPTTDEKTTKIACKSPQ--PDPVDTPASTKQRPKRNLRKADVEEE 2372
L+ + QTP T + T+ +K C P P +P + K R +++
Sbjct: 1589 SLS--VSVVQTPTTFQ-ETEMSPSKEECPRPMSISPPDFSPKTAKSRTPVQDHRSEQSSM 1645
Query: 2373 FLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAE 2432
+ + +P AMD + + D + V + + S Q + K
Sbjct: 1646 SIEFGQESPEQSLAMDFSRQS-PDHPTVGAGVLHITENGPTEVDYSPSDMQDSSLSHKIP 1704
Query: 2433 ALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMK 2492
+E+ P +T+++ + I+ VS P + +S + ++ PL + +
Sbjct: 1705 PMEE----------PSYTQDNDLSELIS-VSQVEASPST--SSAHTPSQIASPLQEDTLS 1751
Query: 2493 E--EPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRK 2550
+ P +S + E Q S++ K SPK + P S T
Sbjct: 1752 DVAPPRDMSLYASLTSEKVQ----------SLEGEKLSPKSDISPLTPRESSPLYSPTFS 1801
Query: 2551 EKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRK 2610
+ A+++ +A H+ S ID + P L DT +
Sbjct: 1802 DSTSAVKEK-------TATCHSSSSPPIDAASAEPYGFRASVLFDTMQHHLALNRDLSTP 1854
Query: 2611 EVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPK 2670
++++ +T G ++ +++P EE + R+P
Sbjct: 1855 GLEKDSGG-----KTPGDFSYAYQKP----------------------EETT----RSPD 1883
Query: 2671 EKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESP-PLEVVDTTASTKRHLRTRVQ 2729
E+ E T S+ G+ E + + TK P +S E + T T
Sbjct: 1884 EEDYDYESYEKTTRTSDVGGYYYEKIE--RTTKSPSDSGYSYETIGKTTKT--------- 1932
Query: 2730 KVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRPRA 2789
P ++ E T E G I S K T P S + R
Sbjct: 1933 -------PEDGDYSYEIIEKTTRTPEEGGYSYDI-----SEKTTSPPEVSGYSYEKTER- 1979
Query: 2790 PRESAQAIEDLAGFKDPA--AGHT--EESMTDDKTTKIPCKSSPELE----DTATSSKRR 2841
S + ++D++ D + GHT + S + + T KI S PE E +T+T + R
Sbjct: 1980 ---SRRLLDDISNGYDDSEDGGHTLGDPSYSYETTEKI--TSFPESEGYSYETSTKTTRT 2034
Query: 2842 PRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGS 2901
P T E E K+T+T +T++ + + T K P++ + D + + S
Sbjct: 2035 PDTSTYCYETAE------KITRTPQASTYSYE--TSDLCYTAEKKSPSEARQDVDLCLVS 2086
Query: 2902 RRQPRAPKEKAQP 2914
+ + PK + P
Sbjct: 2087 SCEYKHPKTELSP 2099
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 64.3 bits (155), Expect = 2e-09
Identities = 361/1822 (19%), Positives = 639/1822 (35%), Gaps = 319/1822 (17%)
Query: 1477 PVCTDKPTTHEKTTKIACRSQPDPVDT---PTSSKPQSKRSLRKVDVEEEFFALRKRTPS 1533
P KP EK K + R + + V P SK + + V+EE ++
Sbjct: 9178 PKVIKKPVI-EKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKV---- 9232
Query: 1534 AGKAMHTPKPAVSGEKNIYAF-------MGTP-VQKLDLTE---NLTGSKRRLQTPK--- 1579
A+HT K +S EK +A + P VQK +TE ++ SKR PK
Sbjct: 9233 --PAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPE 9290
Query: 1580 -EKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLG 1638
+ A E++A + + K K P P K PA+ + +
Sbjct: 9291 LPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPK--VPEVP 9348
Query: 1639 KVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFM-----ESPKQILDSAASLTGS 1693
K V EE + V + G K + ESP +
Sbjct: 9349 KKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVP 9408
Query: 1694 KRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQPDLVDTPTSSKP 1753
+ + P+ + EVP + P+ K+ + EK V P + K
Sbjct: 9409 EERKPVPRKEEEVPPPP-------KVPALPKKPVPEEKVA-----------VPVPVAKKA 9450
Query: 1754 QPKR---SLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPG 1810
P R S + E+ F+A K + + + + + V E++ + ++
Sbjct: 9451 PPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYS--------EEEE 9502
Query: 1811 NLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPADTP 1870
+ S R + R+E+ +A E+T + E+ + P + +EK I+ K +++PA+
Sbjct: 9503 GVSISVYREEEREEEEEA--EVTEY-EVMEEP--EEYVVEEKL--HIISKRVEAEPAEV- 9554
Query: 1871 TNTKQRPKRSLKK----ADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVE 1926
T+++ K+ + K A +EE P K PK V E+K V PV
Sbjct: 9555 --TERQEKKIVLKPKIPAKIEE---------PPPAKVPEAPKKIVPEKK-----VPAPVP 9598
Query: 1927 KLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMT---DDKITEVSCKS 1983
K + + P P+ P + K + +E TE M ++K+ K
Sbjct: 9599 KKEKVPP-PKVPEEPKKPVPEKKVPPKVIKMEEPLPAKV-TERHMQITQEEKVLVAVTKK 9656
Query: 1984 PQPDPVKTPTSSKQRL-KISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAF 2042
P + P K+ + + + K+ K E P K+T+ + K K
Sbjct: 9657 EAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVV----------KEEKVS 9706
Query: 2043 KESAKQMLDPANYGTGMERWPR--TPKEEAQSLEDLAGFKEL--FQTPDHTEESTTDDKT 2098
E+ K+ P T ME R T +EEA S++ ++E + + E T++
Sbjct: 9707 IEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYD 9766
Query: 2099 TKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGIN 2158
+ E + P+ P+ + + EE K K P +
Sbjct: 9767 QYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKP--------KAPPAK----- 9813
Query: 2159 VFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPI-CTDKPTTHEKTT 2217
V ++ ++ P K +P PK +P K++F+ I + E+ T
Sbjct: 9814 VLKKAVPEEKVPVP--IPKKLKPPPPKVPEEP-------KKVFEEKIRISITKREKEQVT 9864
Query: 2218 KIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEK 2277
+ A + P KP+ + K V + +A R P V K ++ + A +E
Sbjct: 9865 EPAAKVPM----------KPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEE- 9913
Query: 2278 DMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKT 2337
+ T V++ + + +E E+ +E+ P K
Sbjct: 9914 -----VVTHVEEYLV-----------EEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKP 9957
Query: 2338 TKIACKSPQPDPVDT---PASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAV 2394
K P P P PA + PK+ K V L +K P K + PK V
Sbjct: 9958 VPEE-KKPVPVPKKKEAPPAKVPEVPKKPEEKVPV----LIPKKEKPPPAKVPEVPKKPV 10012
Query: 2395 SDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESM 2454
+EK V PV K P +K P+ PK+ + V + + P +
Sbjct: 10013 PEEK-----VPVPVPKKV---EAPPAK-VPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEV 10063
Query: 2455 TDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTE 2514
I E +P P+ +++ P KV K EP+ V + E E
Sbjct: 10064 PKKLIPEEKKPTPVPK----------KVEAPPPKVPKKREPVPVP-VALPQEEEVLFEEE 10112
Query: 2515 PTGDSKSIKAFKE---SPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGH 2571
+ + + +E +++L V ++ +E+ E+ V +E F
Sbjct: 10113 IVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVP--- 10169
Query: 2572 TEESMTIDKNTKIPCKSPPPELTDTATSTK---------------RCPKTRPRKEV---- 2612
EE + + K+P +P PE+ T K PK K +
Sbjct: 10170 -EEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPK 10228
Query: 2613 KEELSAVERLTQTSGQSTHTHK---EPASGDEGIKV--------LKQRAKKKPNPV---- 2657
+EE+ VE + + + EP S +E +V +K+ + P PV
Sbjct: 10229 EEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKV 10288
Query: 2658 EEEPSRRRPRAPKEKAQ-PLEDL-AGFTELSETSGHTQESLTAGKATKIPCES--PPLE- 2712
E P++ + P+EK P++ A ++ E E K +P + PP +
Sbjct: 10289 EAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPE-----KKVLVPKKEAVPPAKG 10343
Query: 2713 --VVDTTAST--------KRHLRTRVQKVQVKEEPSAVKFTQTSG-----------ETTD 2751
V++ S K L V + +V+E P +F + E
Sbjct: 10344 RTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIK 10403
Query: 2752 ADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHT 2811
++ E+ ++ + + A V +P+AP + + E + K P
Sbjct: 10404 LEQHRVEEEHRVEKVHRVIEVFEAEEVEVF---EKPKAPPKGPEISEKIIPPKKPPTKVV 10460
Query: 2812 EESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHT 2871
K ++P K E + R P T+ +V +E++ K+
Sbjct: 10461 PRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKV---------- 10510
Query: 2872 DKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHT 2931
PV K +A P K ++V+ ++ P P +K P E+ +
Sbjct: 10511 ---PVPPAKKPEA--PPPKVPEAPKEVVPEKKVPVPPPKK--PEVPPTKVPEVPKAAVPE 10563
Query: 2932 EELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEP-VGDVVSTRDPVKSQSKSNTS 2990
+++ S P + P++ K + ++V AP +P V V P + +
Sbjct: 10564 KKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVP 10623
Query: 2991 LPP------LPFKRGGGKDGSVTGTKRLRCMP------------APEEI-VEELPASKKQ 3031
+PP P K +V K +P PEE+ +EE PA +
Sbjct: 10624 VPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVE 10683
Query: 3032 RVAPRARGKSSEPVVIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISL 3091
P A P + + ++ PA ++ K ++ VPE K +
Sbjct: 10684 EPEPAA------PPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLV 10737
Query: 3092 RSRRQNKTEAE-QQITEVFVLAERIEINRNEKKPMKTSPEMDIQNPDDGARKPIPRDKVT 3150
++ A+ ++ + V +++ + + + P PE +P+ V
Sbjct: 10738 VPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPE-------------VPKKPVL 10784
Query: 3151 ENKRCLRSARQNESSQPKVAEE 3172
E K + + ES P+V EE
Sbjct: 10785 EEKPAVPVPERAESPPPEVYEE 10806
Score = 59.3 bits (142), Expect = 6e-08
Identities = 389/1964 (19%), Positives = 689/1964 (35%), Gaps = 322/1964 (16%)
Query: 1295 AMHTPKPSVGEEKDII-------IFVGTP-VQKLDLTE---NLTGSKRRPQTPKEEAQAL 1343
A+HT K + EEK + V P VQK +TE ++ SKR PK L
Sbjct: 9234 AVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPK--VPEL 9291
Query: 1344 EDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQ---PKTP-LEKRD 1399
+ +E+ P + A K ++P + P E P + PK P + K+
Sbjct: 9292 PEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKP 9351
Query: 1400 VQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKE 1459
V +E + + +V G T +++ P A K+ +
Sbjct: 9352 VPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEER 9411
Query: 1460 KAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVD 1519
K P ++ + + P KP EK + P PV + P+++ S + V
Sbjct: 9412 KPVPRKE-EEVPPPPKVPALPKKPVPEEKV------AVPVPV-AKKAPPPRAEVSKKTVV 9463
Query: 1520 VEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPK 1579
E+ F A K + + + + + VS E+ ++ ++ ++ + R + +
Sbjct: 9464 EEKRFVAEEKLSFAVPQRVEVTRHEVSAEEE----WSYSEEEEGVSISVYREEEREEEEE 9519
Query: 1580 EKAQALEDLAGFKE--------LFQTRGHTEESMTNDKTAK-------VACKSSQPDPDK 1624
+ E + +E + R E + ++ K + K +P P K
Sbjct: 9520 AEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAK 9579
Query: 1625 NPASSKRRLKTSLGKVGV-KEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQI 1683
P + K+ + V K+E + K+ + + P K +K P ++
Sbjct: 9580 VPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPP---KVIKMEEPLPAKV 9636
Query: 1684 LDSAASLTGSKRQL-----RTPKGKSEVPEDLAGFI--ELFQTPSHTKESMTNEKTTKVS 1736
+ +T ++ L + K+ VPE+ + E +E K T+
Sbjct: 9637 TERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFR 9696
Query: 1737 YRASQPDLVDTPTSSK-PQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDI 1795
R + + V + PQP + + + +E ++ S + + + K+
Sbjct: 9697 KRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEF 9756
Query: 1796 NTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTK 1855
+ P ++ DQ R + +E + + E + P PT +
Sbjct: 9757 EEY--EPTEEYDQYEEY--EEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPA 9812
Query: 1856 KILCKSPQSDPADTPTNTKQRPK-----RSLKKADVEEEFLAFRK-----LTPSAGKAMH 1905
K+L K+ + P K +P KK E+ ++ K +T A K
Sbjct: 9813 KVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPM 9872
Query: 1906 TPKAAVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPG 1965
PK V EEK PV + ++ + R P+ PKE E++A F+E T
Sbjct: 9873 KPKRVVAEEK-------VPVPRKEVAPPV----RVPEVPKELEP--EEVA-FEEEVVT-- 9916
Query: 1966 HTEESMTDDK----------ITE------VSCKSPQPDPVKTPTSSKQRLKISLGKVGVK 2009
H EE + +++ ITE + K P+ P K K+ + + K
Sbjct: 9917 HVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEV-PRKPVPEEKKPVPVPKKKEAPP 9975
Query: 2010 EEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGME----RWPRT 2065
+V V K + +E K + K+ + P +E + P
Sbjct: 9976 AKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEV 10035
Query: 2066 PKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRR---PK 2122
PK+ ++ P + K ++ K P E TP + PK
Sbjct: 10036 PKKPVP--------EKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPK 10087
Query: 2123 TPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPR 2182
P KR+ V AL Q + +++ +E+ V E ++++ P + +
Sbjct: 10088 VPK-KREPVPVPVALPQEEEVLFEEEIVPEEE----VLPE--EEEVLPEEEEVLPEEEEV 10140
Query: 2183 TPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRS 2242
P+ + P E+ E P + E ++ + P P PV P I K K +
Sbjct: 10141 LPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPV--PEIKK---KVT 10195
Query: 2243 LRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRW 2302
+K + ++ A + P V K ++ + E+++ PV+ + P P S+
Sbjct: 10196 EKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEV-----LPVEVTEEPEEEPISEEE 10250
Query: 2303 PQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKR 2362
+ +E++A P E K ++P P P
Sbjct: 10251 IPEEPPSIEEVEEVA------------PPRVPEVIKKAVPEAPTPVP------------- 10285
Query: 2363 NLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKR 2422
K ++ P PA +K V PVQK + P +K
Sbjct: 10286 ----------------------KKVEAP-PAKVSKKIPEEKVPVPVQKKEA----PPAK- 10317
Query: 2423 QPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRL 2482
P+ PK+ E + LV KE P ++ ++K++ +F+ K+RL
Sbjct: 10318 VPEVPKKVPEK-KVLVPKKEA--VPPAKGRTVLEEKVSV---------AFRQEVVVKERL 10365
Query: 2483 KIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGS 2542
++ +V+ +++E P E + H + F+E ++ +
Sbjct: 10366 ELEVVEAEVEEIP-----------EEEEFHEVE-------EYFEEGEFHEVEEFIKLEQH 10407
Query: 2543 RRQLRTRKEKARALEDLVDFKEL--FSAPGHTEESMTIDKNTKIPCKSPPPELTDTATST 2600
R + R EK + ++ + +E+ F P + I + IP K PP ++
Sbjct: 10408 RVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKI-IPPKKPPTKVVPRKEPP 10466
Query: 2601 KRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEE 2660
+ P+ P+K V EE V + P KV AKK P +
Sbjct: 10467 AKVPEV-PKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKV 10525
Query: 2661 PSRRRPRAPKEKAQ---PLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTT 2717
P + P++K P + T++ E +A ESPP EV +
Sbjct: 10526 PEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAP 10585
Query: 2718 ASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPA 2777
+ + K E + VK + E K P K + + P A
Sbjct: 10586 KEVVPEKKVPAAPPK-KPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVA 10644
Query: 2778 ASVTGSRRRPRA--------PRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSP 2829
++ P A P E + E++A ++P A EE P ++P
Sbjct: 10645 VP---EKKVPEAIPPKPESPPPEVFEEPEEVA-LEEPPAEVVEE----------PEPAAP 10690
Query: 2830 ELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPA 2889
+ T K P +A V K+ L K+ + E K P+ K +A PA
Sbjct: 10691 P-QVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEA--PPA 10747
Query: 2890 KRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQT 2949
K ++V+ ++ K + P A E+ + P E+ A + S P +
Sbjct: 10748 KVPEVPKEVVPEKKVAVPKKPEVPP----AKVPEVPKKPVLEEKPAVPVPERAESPPPEV 10803
Query: 2950 PDSGKPLKISRRVLRAPKVE-PVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDGSVTG 3008
+ +P +I+ AP+ E PV PV + + P +P +
Sbjct: 10804 YE--EPEEIAPEEEIAPEEEKPV--------PVAEEEEPEVPPPAVPEE----------- 10842
Query: 3009 TKRLRCMPAPEEIVEE--LPASKKQRVAPRARGKSSEPV-VIMKRSLRTSAKRIEPAEEL 3065
P++I+ E +P KK P K EP VI K L+ PA
Sbjct: 10843 ---------PKKIIPEKKVPVIKKPEAPPP---KEPEPEKVIEKPKLKPRPPPPPPAPP- 10889
Query: 3066 NSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKKPM 3125
KE+ K K L++ + K + Q+ E L +++ EKK
Sbjct: 10890 --------KEDVK-------EKIFQLKAIPKKKVPEKPQVPEKVELTP-LKVPGGEKKVR 10933
Query: 3126 KTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKV 3169
K PE RKP P+++V K LR ++ E +PKV
Sbjct: 10934 KLLPE----------RKPEPKEEVV-LKSVLR--KRPEEEEPKV 10964
Score = 55.1 bits (131), Expect = 1e-06
Identities = 271/1400 (19%), Positives = 490/1400 (35%), Gaps = 222/1400 (15%)
Query: 1866 PADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAA--VGEEKDINTFVGT 1923
PA P P + +KK +E+ R++ + P+ + + +K T
Sbjct: 9166 PAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRT---- 9221
Query: 1924 PVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKS 1983
PV++ + +P + E+ + P +E +T++KI K
Sbjct: 9222 PVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKR 9281
Query: 1984 PQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVG---KLTQTSGKTTQTHRETAGDGKSIK 2040
+P P K P L + EEV PV K+ + K + ++ + K K
Sbjct: 9282 VEPPP-KVP---------ELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEK--K 9329
Query: 2041 AFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKEL--FQTPDHTEESTTDDKT 2098
K+ P + P+ P E + +A KE + P+ + T++K
Sbjct: 9330 PVPVPKKEPAAPPK----VPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKI 9385
Query: 2099 TKIACK--SPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKG 2156
T + + SPPP + P + K P ++ + + + + K P E+K
Sbjct: 9386 TIVTQREESPPPAVPEIP-----KKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEK- 9439
Query: 2157 INVFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKT 2216
+ V AK+ P A V+ K + +A K F P + T HE +
Sbjct: 9440 VAVPVPVAKKAPPPRAEVS--------KKTVVEEKRFVAEEKLSFAVPQRVEV-TRHEVS 9490
Query: 2217 TKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEE-------ESLALRKRTPSVGKAMDTP 2269
+ + + + ++++ + + +A+V E E + ++ + K ++
Sbjct: 9491 AEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEA- 9549
Query: 2270 KPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTD 2329
+PA E+ K K+ L +P P K P
Sbjct: 9550 EPAEVTERQEK--------KIVLKPKIPAKIEEPPPAK-----------------VPEAP 9584
Query: 2330 KPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDT 2389
K EK K+ P+ + V P + PK+ + + K+ P M+
Sbjct: 9585 KKIVPEK--KVPAPVPKKEKVPPP-KVPEEPKKPVPE-----------KKVPPKVIKMEE 9630
Query: 2390 PKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPK-----EKAEALEDLVGFKELF 2444
P PA E+++ E V P R P+ PK EK L+ +
Sbjct: 9631 PLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPA 9690
Query: 2445 QTPGHTEESMTDDKIT-EVSCKSPQPESFKTSRSSKQR---LKIPLVKVDMKEEPLAVSK 2500
+ + + ++K++ E + PQP T K+R L+ V V +EE +
Sbjct: 9691 KVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEE 9750
Query: 2501 LTRTSGE----TTQTHTEPTGDSKSIKAFKESPKQILD-----PAASVTGSRRQLRTRKE 2551
E T + + + + ++E + I + P V + +
Sbjct: 9751 YDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAP 9810
Query: 2552 KARALEDLVDF--------KELFSAPGHT--EESMTIDKNTKIP-CKSPPPELTDTATST 2600
A+ L+ V K+L P E ++ +I K ++T+ A
Sbjct: 9811 PAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKV 9870
Query: 2601 KRCPK--------TRPRKEV---------------------KEELSAVER-LTQTSGQST 2630
PK PRKEV +E ++ VE L + +
Sbjct: 9871 PMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYI 9930
Query: 2631 HTHKEPASGDEGIKVLKQRA----------KKKPNPV---EEEPSRRRPRAPKEKAQPLE 2677
H +E + +E + V+ + +KKP PV +E P + P PK+ + +
Sbjct: 9931 HEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVP 9990
Query: 2678 DLAGFTELSETSGHTQESLTAGKATKIP------CESPPLEVVDTTASTKRHLRTRVQKV 2731
L E + + K+P E+PP +V + + V
Sbjct: 9991 VLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAP 10050
Query: 2732 QVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKA--LKESAKQTPAPAASVTGSRRRPRA 2789
+ E P A K + + +K+P K ++A K K+ P P
Sbjct: 10051 KKVEAPPA-KVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLF 10109
Query: 2790 PRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKV 2849
E E L ++ E +++ + PE E+ + P ++
Sbjct: 10110 EEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVP--EEEEF 10167
Query: 2850 EVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQ---PAK-----RKLDAEDVIGS 2901
+EE+L K K+ V E K K+ PAK +K++ + +I
Sbjct: 10168 VPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILP 10227
Query: 2902 RRQPRAPKE-KAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKPLKISR 2960
+ + P E +P E+ S +E+ + P EE+ AP + P+ I +
Sbjct: 10228 KEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEE-------VAPPRVPE-----VIKK 10275
Query: 2961 RVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDGSVTGTKRLRCMPAPEE 3020
V AP PV V P K K P+P ++ V P++
Sbjct: 10276 AVPEAP--TPVPKKVEA-PPAKVSKKIPEEKVPVPVQKKEAPPAKVP--------EVPKK 10324
Query: 3021 IVEELPASKKQRVAPRARGKS--SEPVVIMKRSLRTSAKRIE-PAEELNSNDMKTNKEEH 3077
+ E+ K+ P A+G++ E V + R +R+E E ++ +E H
Sbjct: 10325 VPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFH 10384
Query: 3078 KLQDSVPE------NKGISLRSRR---QNKTEAEQQITEVFVLAERIEINRNEKKPMKTS 3128
++++ E + I L R +++ E ++ EVF AE +E+ K P K
Sbjct: 10385 EVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFE-AEEVEVFEKPKAPPK-G 10442
Query: 3129 PEMD--IQNPDDGARKPIPR 3146
PE+ I P K +PR
Sbjct: 10443 PEISEKIIPPKKPPTKVVPR 10462
Score = 42.7 bits (99), Expect = 0.006
Identities = 139/717 (19%), Positives = 229/717 (31%), Gaps = 131/717 (18%)
Query: 1968 EESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQ 2027
+E + + K+ K P+ P K P + K EV+P K+ K +
Sbjct: 10502 KEVVPEKKVPVPPAKKPEAPPPKVPEAPK--------------EVVPEKKVPVPPPKKPE 10547
Query: 2028 THRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLE-DLAGFKELFQTP 2086
+ ++ + + P E P PKE + A K+ TP
Sbjct: 10548 VPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEV-PEAPKEVVPEKKVPAAPPKKPEVTP 10606
Query: 2087 DHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHT 2146
E+ + K PP + PT PK + ++ + E +
Sbjct: 10607 VKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIP----------- 10655
Query: 2147 DKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPIC 2206
P E VF E + L+ + + +P P Q +
Sbjct: 10656 ---PKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPP----------------QVTVP 10696
Query: 2207 TDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAM 2266
KP +K + + P+ PV P + K V ++ A + P V K +
Sbjct: 10697 PKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEV 10756
Query: 2267 DTPKPAGGDEKDMKAFMGTP-VQK---LDLPGNLPGSKRWPQTPKEKAQALEDLAGFKEL 2322
K +K P V K L+ +P +R P E + E++A +E+
Sbjct: 10757 VPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEI 10816
Query: 2323 FQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPS 2382
P +KP + + +P P + + PK+ + + K+ P
Sbjct: 10817 --APEEEKPVP---------VAEEEEPEVPPPAVPEEPKKIIPE-----------KKVPV 10854
Query: 2383 AGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKE 2442
K P EK +E P K + P P E +++ + +
Sbjct: 10855 IKKPEAPPPKEPEPEK----VIEKPKLK---------PRPPPPPPAPPKEDVKEKIFQLK 10901
Query: 2443 LFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLT 2502
E+ +K+ K P E K R +P K + KEE + S L
Sbjct: 10902 AIPKKKVPEKPQVPEKVELTPLKVPGGEK-------KVRKLLPERKPEPKEEVVLKSVLR 10954
Query: 2503 RTSGETTQTHTEPTGDSKSIKAFKES-------PKQILDPAASVTGSRRQLRTRKEKARA 2555
+ E EP + K ++ K+ PK + + R + K
Sbjct: 10955 KRPEEE-----EPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPE 11009
Query: 2556 LEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEE 2615
++ + P E TI K PP E T + P T P K E
Sbjct: 11010 IKPAIPLPAPEPKPKPEAEVKTI--------KPPPVEPEPTPIAA---PVTVPVVGKKAE 11058
Query: 2616 LSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEK 2672
A KE A+ +G +K KK P+P+E E + RP + EK
Sbjct: 11059 AKAP--------------KEEAAKPKG--PIKGVPKKTPSPIEAERRKLRPGSGGEK 11099
Score = 40.8 bits (94), Expect = 0.022
Identities = 142/681 (20%), Positives = 234/681 (34%), Gaps = 100/681 (14%)
Query: 2256 RKRTPSVGKAMDTPKPAGGDEK----DMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQ 2311
RK P+ K + PK +EK + T V ++ P + K+ P P +K +
Sbjct: 10462 RKEPPA--KVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPE 10519
Query: 2312 ALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEE 2371
A + P K EK + P P P + PK + + V E
Sbjct: 10520 APPP--------KVPEAPKEVVPEKKVPVP---PPKKPEVPPTKVPEVPKAAVPEKKVPE 10568
Query: 2372 EFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVE----TPVQKLDLLGNLPGSKRQPQTP 2427
+ P + + PK V ++K + TPV+ + + K+ P P
Sbjct: 10569 AIPPKPESPPP--EVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPP 10626
Query: 2428 KEKAEALEDLVGFKELFQTPGHTEESMTDDKITEV---SCKSPQPESFKTSRSSKQRLKI 2484
+K E V P + ++ + K+ E +SP PE F+ + L+
Sbjct: 10627 PKKPEVPPTKV--------PEVPKVAVPEKKVPEAIPPKPESPPPEVFE--EPEEVALEE 10676
Query: 2485 PLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRR 2544
P +V + EP A ++T +P + K+ + P+ P V +
Sbjct: 10677 PPAEVVEEPEPAAPPQVTVPP-------KKPVPEKKAPAVVAKKPEL---PPVKVPEVPK 10726
Query: 2545 QLRTRKEKARALEDLVDFKELFSAPGHTEE---SMTIDKNTKIPCKS--PPPELTDTATS 2599
++ K+ LV K+ + P E + +K +P K PP ++ +
Sbjct: 10727 EVVPEKKVP-----LVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEV--- 10778
Query: 2600 TKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEE 2659
P+K V EE AV + ++EP ++ + K P EE
Sbjct: 10779 --------PKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEE 10830
Query: 2660 EPSRRRPRAPKE--KAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTT 2717
EP P P+E K P + + + E + K+ PP
Sbjct: 10831 EPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPK 10890
Query: 2718 ASTKRHL--RTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPA 2775
K + + K +V E+P + + + K P GE K K L E + P
Sbjct: 10891 EDVKEKIFQLKAIPKKKVPEKPQVPEKVELT-----PLKVPGGEKKVRKLLPE---RKPE 10942
Query: 2776 PAASVTGSRRRPRAPRESAQAIE--DLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELED 2833
P V + P E +E L K PA P K E+E
Sbjct: 10943 PKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPP-----------PPKPVEEVEV 10991
Query: 2834 TATSSKRRPRTRAQKV-EVKEELLAVGKLTQTSGET-THTDKEPVGEGKGTKAFKQPAKR 2891
+ + R KV E+K + + E T K P E + T P
Sbjct: 10992 PTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPT-----PIAA 11046
Query: 2892 KLDAEDVIGSRRQPRAPKEKA 2912
+ V+G + + +APKE+A
Sbjct: 11047 PVTV-PVVGKKAEAKAPKEEA 11066
Score = 38.1 bits (87), Expect = 0.14
Identities = 68/304 (22%), Positives = 117/304 (38%), Gaps = 32/304 (10%)
Query: 2628 QSTHTHKEPASGDEGIKVLKQRAKKKPN----PVEEEPSRRRPRAPKEKAQPLEDLAGFT 2683
+ +H K PA KV +++A P PV E+ + R +EK Q T
Sbjct: 9158 EESHERKVPA------KVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQ-------VT 9204
Query: 2684 ELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVK--EEPSAVK 2741
++ E S + + K ++ P + +EV TK+ + + + EE +V
Sbjct: 9205 KVPEVS----KKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVT 9260
Query: 2742 FTQTSGETTDADKEPAGEDKGI----KALKESAKQTPAPAASVTGSRR-RPRAPRESAQA 2796
+ E +K K + K + K P A V ++ P AP+
Sbjct: 9261 VPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVP 9320
Query: 2797 IEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELL 2856
+ + K P +E K ++P K PE + +K++ A+ EV++ ++
Sbjct: 9321 KKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVV 9380
Query: 2857 AVGKLT-QTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPL 2915
K+T T E + P K ++P RK E+V + P PK K P
Sbjct: 9381 TEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRK--EEEVPPPPKVPALPK-KPVPE 9437
Query: 2916 EDLA 2919
E +A
Sbjct: 9438 EKVA 9441
Score = 37.0 bits (84), Expect = 0.32
Identities = 100/525 (19%), Positives = 193/525 (36%), Gaps = 93/525 (17%)
Query: 1962 QTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQT 2021
+ P +E + + K+ K P+ PVK P + K EV+P K+
Sbjct: 10580 EVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPK--------------EVVPEKKVPVP 10625
Query: 2022 SGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEA-QSLEDLAGFK 2080
K + + + ++ + + P P +P E + E++A +
Sbjct: 10626 PPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPK---------PESPPPEVFEEPEEVALEE 10676
Query: 2081 ELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGK-----RDIVEELS 2135
+ + E + T + K P PE P ++P+ P K +++V E
Sbjct: 10677 PPAEVVEEPEPAAPPQVT--VPPKKPVPEK-KAPAVVAKKPELPPVKVPEVPKEVVPEKK 10733
Query: 2136 ALKQLTQTTHTD--KVPGDEDKGINVFRETAKQKLD-PAASVTGSKRQPRTPKGKAQPLE 2192
+ + KVP + + + +K + P A V ++P + A P+
Sbjct: 10734 VPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVP 10793
Query: 2193 DLAGL--KELFQTP--ICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSL---RK 2245
+ A E+++ P I ++ E+ + + V P + P+ + + +K
Sbjct: 10794 ERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAV--PEEPKKIIPEKK 10851
Query: 2246 ADVEEESLALRKRTPSVGKAMDTPK-----------PAGGDEKD----MKAFMGTPV--- 2287
V ++ A + P K ++ PK P D K+ +KA V
Sbjct: 10852 VPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEK 10911
Query: 2288 ----QKLDL-PGNLPGSKRWPQ--TPKEKAQALEDLAGFKELFQTPGTDKPTTD----EK 2336
+K++L P +PG ++ + P+ K + E++ L + P ++P + EK
Sbjct: 10912 PQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEK 10971
Query: 2337 TTKIACKSPQP----DPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKP 2392
K A P P + V+ P TK+ RK + ++ P + P+P
Sbjct: 10972 VKKPAVPEPPPPKPVEEVEVPTVTKRE-----RKIPEPTKVPEIKPAIP-----LPAPEP 11021
Query: 2393 AVSDEKNINTFVETPVQ------KLDLLGNLPGSKRQPQTPKEKA 2431
E + T PV+ + + G K + + PKE+A
Sbjct: 11022 KPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEA 11066
Score = 34.7 bits (78), Expect = 1.6
Identities = 30/104 (28%), Positives = 42/104 (40%), Gaps = 21/104 (20%)
Query: 522 PPNTPLKRGEAPT--KRKSLVMH---TPPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSL 576
PP P++ E PT KR+ + P + I P+P K E+ EVK
Sbjct: 10981 PPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEA------EVKT--- 11031
Query: 577 VISPPAPSPRKTPVASDQRRRSCKTAPASSSKSQTEVPKRGGRK 620
I PP P TP+A+ T P K++ + PK K
Sbjct: 11032 -IKPPPVEPEPTPIAAP------VTVPVVGKKAEAKAPKEEAAK 11068
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 62.8 bits (151), Expect = 5e-09
Identities = 159/787 (20%), Positives = 291/787 (36%), Gaps = 114/787 (14%)
Query: 2500 KLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDL 2559
+L+R S + + +E GDS E P++ G RR R R+ +A L +
Sbjct: 197 ELSRHSPRKSSSISEEKGDSDD-----EKPRK---------GERRSSRVRQARAAKLSE- 241
Query: 2560 VDFKELFSAPGHTEESM-TIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSA 2618
S P EE T +N ++ R KT +E +EE
Sbjct: 242 ------GSQPAEEEEDQETPSRNLRV--------------RADRNLKTEEEEEEEEEEEE 281
Query: 2619 VERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLED 2678
+ + + + + P +K K+ ++ P EE RP+ ++ + LE
Sbjct: 282 DDEEEEGDDEGQKSREAPI-----LKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLER 336
Query: 2679 LAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPS 2738
FT E + + L + K + PLE + + + L+ + + PS
Sbjct: 337 GGRFTRSQEEA--RKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEK------SKSPS 388
Query: 2739 AVKFTQTSGETTDADKEPAGEDKGIKALKE---SAKQTPAPAASVTGSRRRPRAPRESAQ 2795
+ T+ D++ A + AL E S ++TP P + S P S +
Sbjct: 389 PPRLTE--------DRKKA----SLVALPEQTASEEETPPPLLTKEASSPPPHPQLHSEE 436
Query: 2796 AIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSP-----ELEDTATSSKRRPRTRAQKVE 2850
IE + G P TD T ++ L ++ S + + A+KV
Sbjct: 437 EIEPMEGPAPPVLIQLSPPNTDADTRELLVSQHTVQLVGGLSPLSSPSDTKAESPAEKVP 496
Query: 2851 VKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLD----AEDVIGS-RRQP 2905
+E +L + + + + + D EP + QP K++ A+ + +QP
Sbjct: 497 -EESVLPLVQKSTLADYSAQKDLEPESDRSA-----QPLPLKIEELALAKGITEECLKQP 550
Query: 2906 R-APKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSG-----KPLKIS 2959
KE + L L Q+ + ++ ++ S + + ++PDS PL+
Sbjct: 551 SLEQKEGRRASHTLLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSK 610
Query: 2960 RR-VLRA-----PKVEPVGDVVST---RDPVKSQSKSNTSLPPLPFKRGGGKDGSVTGTK 3010
+R V +A P+ P ST R +S+S+S +S G +D S + T+
Sbjct: 611 QRDVAQARTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSLSPGVSRDSSTSYTE 670
Query: 3011 RLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEPAEELNSNDM 3070
P+ + V P + Q P+ R +S V +R + + + L
Sbjct: 671 TKD--PSSGQEVATPPVPQLQVCEPKERTSTSSSSVQARRLSQPESAEKHVTQRLQPERG 728
Query: 3071 KTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKKPMKTSPE 3130
K E + + + + ++ + E+E +I E + ++ +E +P PE
Sbjct: 729 SPKKCEAEEAEPPAATQPQTSETQTSHLPESE-RIHHTVEEKEEVTMDTSENRPENDVPE 787
Query: 3131 MDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKVLMQNQKGKG 3190
+ D + P V + ++ ESS PK + K+ + +
Sbjct: 788 PPMPIADQVSNDDRPEGSVEDEEK-------KESSLPKSFKR-------KISVVSATKGV 833
Query: 3191 EAGNSDSMCLRSRKTKSQPA--ASTLESKSVQRVTRSVKRCAENPKKAEDNVCVKKIRTR 3248
AGNSD+ + + + A A+T + S+ T S+K + K V +
Sbjct: 834 PAGNSDTEGGQPGRKRRWGASTATTQKKPSISITTESLKSLIPDIKPLAGQEAVVDLHAD 893
Query: 3249 SHRDSED 3255
R SED
Sbjct: 894 DSRISED 900
Score = 38.5 bits (88), Expect = 0.11
Identities = 115/624 (18%), Positives = 212/624 (33%), Gaps = 111/624 (17%)
Query: 1332 RPQTPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQP 1391
RP+T +E + LE G+ T+ E+ A +
Sbjct: 323 RPKTRSQEQEVLE-------------------RGGRFTRSQEEARKSHLARQQQEKEMKT 363
Query: 1392 KTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRE-TAKQKLDPAASVTG 1450
+PLE+ + +E+ + + L + S + + S+ A E TA ++ P +T
Sbjct: 364 TSPLEEEE--REIKSSQGLKEKSKSPSPPRLTEDRKKASLVALPEQTASEEETPPPLLTK 421
Query: 1451 SKRHPK------TKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTK--IACRSQPDPVD 1502
P ++E+ +P+E A + +P TD T ++ + P+
Sbjct: 422 EASSPPPHPQLHSEEEIEPMEGPAPPVLIQLSPPNTDADTRELLVSQHTVQLVGGLSPLS 481
Query: 1503 TPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKL 1562
+P+ +K +S KV E ++K T + A +P + +++L
Sbjct: 482 SPSDTKAESPAE--KVPEESVLPLVQKSTLADYSAQKDLEPESDRSAQP---LPLKIEEL 536
Query: 1563 DLTENLTGS--KRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQP 1620
L + +T K+ KE +A L L Q+ + ++ ++ +S P
Sbjct: 537 ALAKGITEECLKQPSLEQKEGRRASHTLLPSHRLKQSADSSSSRSSSSSSSSSRSRSRSP 596
Query: 1621 DPD----KNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAF 1676
D +P SK+R +G + + + + S K+
Sbjct: 597 DSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSL 656
Query: 1677 MESPKQILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVS 1736
SP DS+ S T +K P EV +++ + T S ++ +
Sbjct: 657 --SPGVSRDSSTSYTETK----DPSSGQEVATPPVPQLQVCEPKERTSTSSSSVQAR--- 707
Query: 1737 YRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDIN 1796
R SQP+ + + + QP+R +P +A PA + +
Sbjct: 708 -RLSQPESAEKHVTQRLQPERG----------------SPKKCEAEEAEPPAATQPQTSE 750
Query: 1797 TFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKK 1856
T Q +LP S R T +EK + + + R P P D+
Sbjct: 751 T----------QTSHLPESERIHHTVEEKEEVTMDTSENRPENDVPEPPMPIADQ----- 795
Query: 1857 ILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKD 1916
+ RP+ S++ + +E L PK+ +
Sbjct: 796 --------------VSNDDRPEGSVEDEEKKESSL---------------PKSFKRKISV 826
Query: 1917 INTFVGTPVEKLDLLGNLPGSKRR 1940
++ G P D G PG KRR
Sbjct: 827 VSATKGVPAGNSDTEGGQPGRKRR 850
Score = 36.6 bits (83), Expect = 0.42
Identities = 115/658 (17%), Positives = 220/658 (33%), Gaps = 119/658 (18%)
Query: 891 SKSEETNTEIVECILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDEKMKAMKR 950
S SEE E K ++++ ++Q R ++ E +P E +E+ E + +++A +
Sbjct: 208 SISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEE-EEDQETPSRNLRVRADRN 266
Query: 951 SRTWGQKCAPMSDLTDLKSLPDTELMKDTARGQNLLQTQDHAKAP-----KSEKGKITKM 1005
+T + + + E +D + + Q +AP K E +I ++
Sbjct: 267 LKT------------EEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRV 314
Query: 1006 PCQSLQPEPINTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETTHTHREPAGDGKSI 1065
+ + E T + ++ L+ G+FTR+ E +H K +
Sbjct: 315 KPEEMMDERPKTRSQEQEVLERG-------------GRFTRSQEEARKSHLARQQQEKEM 361
Query: 1066 RTFKESPKQILDPAARVTGMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTT 1125
+T SP + EE + ++ G KE ++P P + +K +
Sbjct: 362 KT--TSPLE-------------------EEEREIKSSQGLKEKSKSPSPPRLTEDRKKAS 400
Query: 1126 KIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLALRKLTPSAGKAMLTPKPAGGDEK 1185
+A +TP LT A P P E+
Sbjct: 401 LVALPEQTASEEETPPPL----------------------LTKEASSP--PPHPQLHSEE 436
Query: 1186 DIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGK 1245
+I+ + G P QL P A E L HT +LV
Sbjct: 437 EIEP----------MEGPAPPVLIQLSPPNTDADTRELLVS--------QHTVQLVGGLS 478
Query: 1246 TTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGE 1305
P D+ P + P ++K+ + + A ++L P + ++ P P E
Sbjct: 479 PLSSPSDTKAESPAEKVPEESVLPL--VQKSTL-ADYSAQKDLEPESDRSAQ-PLPLKIE 534
Query: 1306 EKDIIIFVGTPVQKLDLTENLTGSKRR-----PQTPKEEAQALEDLTGFKELFQTPGHTE 1360
E + + K E G + K+ A + + + +
Sbjct: 535 ELALAKGITEECLKQPSLEQKEGRRASHTLLPSHRLKQSADSSSSRSSSSSSSSSRSRSR 594
Query: 1361 EAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHT 1420
++G + P S + A T + + + R + S + ++++ +
Sbjct: 595 SPDSSGSRSHSPLRSKQRDVAQARTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRK 654
Query: 1421 DKVPGGEDKSINAFRETAK---------------QKLDPAASVTGSKRHPKTKEKAQPLE 1465
PG S ++ ET Q +P + S + + +QP
Sbjct: 655 SLSPGVSRDSSTSYTETKDPSSGQEVATPPVPQLQVCEPKERTSTSSSSVQARRLSQPES 714
Query: 1466 DLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEE 1523
+ + Q + K E+ A +QP +T TS P+S+R V+ +EE
Sbjct: 715 AEKHVTQRLQPERGSPKKCEAEEAEPPAA-TQPQTSETQTSHLPESERIHHTVEEKEE 771
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 62.0 bits (149), Expect = 9e-09
Identities = 300/1473 (20%), Positives = 492/1473 (33%), Gaps = 237/1473 (16%)
Query: 1911 VGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEES 1970
V E+ F+ PV LD+ + + + K KA+ L K P T ES
Sbjct: 30 VKEQSGQKCFLAQPVTLLDIYTHWQQTSELGR--KRKAEEDAALQAKKTRVSDPISTSES 87
Query: 1971 MTDDKITEVSCKSPQPDPVKT---------PTSSKQRLKISLGKVGVKEEVLP---VGKL 2018
+++ E P T P+S K++ K K G +P GK
Sbjct: 88 SEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKT 147
Query: 2019 TQT--SGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDL 2076
SGK+ R++A + E+ ++ PA +G + + + S ED
Sbjct: 148 VANLLSGKSP---RKSAEPSANTTLVSETEEEGSVPA-FGAAAKPGMVSAGQADSSSEDT 203
Query: 2077 AGFKELFQTPDHTE-ESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELS 2135
+ + D T+ E +K ++ S P + +T P P + +
Sbjct: 204 SS------SSDETDVEVKASEKILQVRAASAPAKGTPGKGAT---PAPPGKAGAVASQTK 254
Query: 2136 ALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGS-----KRQPR-----TPK 2185
A K + + + D ++ + + K S G+ K PR P
Sbjct: 255 AGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPP 314
Query: 2186 GKAQPL--EDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSL 2243
GK P + AG +E D ++ E++ Q P G
Sbjct: 315 GKTGPAVAKAQAGKRE-------EDSQSSSEESDSEEEAPAQAKPSG------------- 354
Query: 2244 RKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWP 2303
KA + A K +P G A P+ G ++ +G + S R
Sbjct: 355 -KAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQ--VGKQEEDSRSSSEESDSDR-- 409
Query: 2304 QTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRN 2363
+A A + A K L ++P +T P P PA+ P
Sbjct: 410 -----EALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT----PSAQ 460
Query: 2364 LRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQ 2423
+ K + + E + S G+ PA EK++ ++ G P K
Sbjct: 461 VGKWEEDSESSSEESSDSSDGEVPTAVAPA--QEKSLGNILQAKPTSSPAKG--PPQKAG 516
Query: 2424 PQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLK 2483
P + KAE D + E +D S S + + T+ +K LK
Sbjct: 517 PVAVQVKAEKPMD----------NSESSEESSD------SADSEEAPAAMTAAQAKPALK 560
Query: 2484 IPLVKVDMKEEPLAVSKLTRTSGETTQ------THTEPTGDSKSIKAFKESP------KQ 2531
IP K K+ S TQ T T P G S ++ + P +
Sbjct: 561 IPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSE 620
Query: 2532 ILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSA---------PGHTEESMTIDKNT 2582
D TG + K + L+ + + PG T ++T K
Sbjct: 621 ESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAE 680
Query: 2583 KIPCKSPPPELTDT--ATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGD 2640
K E +D+ A ++ KT +K + A R G T P
Sbjct: 681 KQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKG----TISAPGKVV 736
Query: 2641 EGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGK 2700
KQR+ K P P A + P A T +G ++S ++ +
Sbjct: 737 TAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEE 796
Query: 2701 ATKIPCESPPLEVVDTTASTKRHLRT---RVQKVQVKEEPSAVKFTQTSGETTDADKEPA 2757
ES E +T A K +T R KE P G+T + +
Sbjct: 797 ------ESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAG 850
Query: 2758 GEDKGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTD 2817
+D + +ES APAA SAQ I+ F DP + T
Sbjct: 851 KQDDSGSSSEESDSDGEAPAAVT------------SAQVIKPPLIFVDPNRSPAGPAATP 898
Query: 2818 DKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEV--KEELLAVGKLTQT-SGETTHTDKE 2874
+ S+P + S+ R + ++ +V + L G T + T H
Sbjct: 899 ---AQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIA 955
Query: 2875 PVGEGKGTKAFKQPAK----RKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGH 2930
P G + K+ ++ +K + S++ P + L+ LA +Q P
Sbjct: 956 PKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVA 1015
Query: 2931 TEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTS 2990
+ ++G + + P +P S LR PK+ V +T+ P S ++S
Sbjct: 1016 RTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQ--ATKAPESSDDSEDSS 1073
Query: 2991 LPPLPFKRGGGKDG-SVTGTKRLRCMPAP-----EEIVEELPA--SKKQRVAPR---ARG 3039
G +DG G K + P E +VEE A S+ VAP G
Sbjct: 1074 ----DSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSG 1129
Query: 3040 KSSEPVVIMKRSLRTSAKRIEPAEELNS----NDMKTNKEEHKLQDSV----PENKG--- 3088
+ + + +++ + ++S D K+E K Q + P+ G
Sbjct: 1130 YMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEA 1189
Query: 3089 ----ISLRSRRQNK---------------------------TEAEQQITEVFVLAERIEI 3117
+SR+ K EA+ Q + V VL E +E
Sbjct: 1190 ASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQ 1249
Query: 3118 NRNEKKPMKTSPEMDIQNPDDGARK-----PIPRDKVTENKRCLRSARQNES--SQPKVA 3170
R KK + T+ E + + RK P R ++ K+ L + E+ S K +
Sbjct: 1250 ER--KKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTS 1307
Query: 3171 EESGG---QKSAKVLMQNQKGKGEAGNSDSMCLRSRKTKSQPAASTLES------KSVQR 3221
S G + A ++ +KGKG G+ + + + Q T+E KS +
Sbjct: 1308 TTSKGKAKRDKASGDVKEKKGKGSLGSQGAK--DEPEEELQKGMGTVEGGDQSNPKSKKE 1365
Query: 3222 VTRSVKRCAENPKKAEDNVCVKKIRTRSHRDSE 3254
+S KR + KK + KK + S +DSE
Sbjct: 1366 KKKSDKRKKDKEKKEKK----KKAKKASTKDSE 1394
>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
Length = 3664
Score = 61.6 bits (148), Expect = 1e-08
Identities = 127/534 (23%), Positives = 198/534 (37%), Gaps = 64/534 (11%)
Query: 2563 KELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERL 2622
KE P E+ + + K P +P + ++ T P P V SA L
Sbjct: 1598 KEKDQKPKEVEKQEDTENHPKTPESAPENKDSELKTPPSVGP---PSVTVVTLESAPSAL 1654
Query: 2623 TQTSGQST--------HTHKEPASGDEGIKVLKQRAKKKPNPVEE-EPSRRRPRAPKEKA 2673
+T+G T EPA+ E K + A P PVE+ E P A +K
Sbjct: 1655 EKTTGDKTVEAPLVTEEKTVEPATVSEEAKPASEPA---PAPVEQLEQVDLPPGADPDKE 1711
Query: 2674 QPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRVQKVQV 2733
+ AG E S SG L A T S VD + + L QK +
Sbjct: 1712 AAMMP-AGVEEGS--SGDQPPYLDAKPPTPGASFSQAESNVDPEPDSTQPLSKPAQKSEE 1768
Query: 2734 KEEPSAVKFTQTSGETTDADKE---------PAGED---------KGIKALKESAKQTPA 2775
EP A K T+ DA+++ PA ED K K K +TP
Sbjct: 1769 ANEPKAEKPDATADAEPDANQKAEAAPESQPPASEDLEVDPPVAAKDKKPNKSKRSKTPV 1828
Query: 2776 PAASVT-----GSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPE 2830
AA+V+ +R+ R RE + G A E M +K T+ K+S
Sbjct: 1829 QAAAVSIVEKPVTRKSERIDREKLKRSNSPRG---EAQKLLELKMEAEKITRTASKNSAA 1885
Query: 2831 LEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAK 2890
D P +R ++ V+ +G E KEPV + + T+ K+ +
Sbjct: 1886 --DLEHPEPSLPLSRTRRRNVRSVYATMG-----DHENRSPVKEPVEQPRVTR--KRLER 1936
Query: 2891 RKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTP 2950
+A V + R+ R PK + + E+ + ++ P T + G + ++T
Sbjct: 1937 ELQEAAAVPTTPRRGRPPKTRRRADEEE---ENEAKEPAETLKPPEGWR---SPRSQKTA 1990
Query: 2951 DSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGG---KDGSVT 3007
G P ++ PKV+ +T + K ++ P + G +D
Sbjct: 1991 AGGGPQ--GKKGKNEPKVDATRPEATTEVGPQIGVKESSMEPKAAEEEAGSEQKRDRKDA 2048
Query: 3008 GTKRLRCMPAPEEIVEELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEP 3061
GT + AP E+VE+ PA +K + R R ++S V SL+ + P
Sbjct: 2049 GTDKNPPETAPVEVVEKKPAPEKNSKSKRGRSRNSRLAVDKSASLKNVDAAVSP 2102
Score = 55.5 bits (132), Expect = 9e-07
Identities = 177/928 (19%), Positives = 313/928 (33%), Gaps = 144/928 (15%)
Query: 2135 SALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDL 2194
S +LT+ +K + K + +T P ++ + +TP P +
Sbjct: 1585 SRFMELTRMQQKEKEKDQKPKEVEKQEDTENHPKTPESAPENKDSELKTPPSVGPPSVTV 1644
Query: 2195 AGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKP--QSKRSLRKADVEEES 2252
L+ P+ EKTT G T+ P ++++ A V EE+
Sbjct: 1645 VTLESA---------PSALEKTT------------GDKTVEAPLVTEEKTVEPATVSEEA 1683
Query: 2253 LALRKRTPS-VGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQ 2311
+ P+ V + P G D A M V++ P P TP
Sbjct: 1684 KPASEPAPAPVEQLEQVDLPPGADPDKEAAMMPAGVEEGSSGDQPPYLDAKPPTPGASFS 1743
Query: 2312 ALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEE 2371
E + P + +P + P+ + D A + D +
Sbjct: 1744 QAES-----NVDPEPDSTQPLSKPAQKSEEANEPKAEKPDATADAEP---------DANQ 1789
Query: 2372 EFLALRKRTPSAGKAMDTPKPAVSDEKNINTFV--ETPVQKLDL-LGNLPGSKRQPQTPK 2428
+ A + P A + ++ P + +K N +TPVQ + + P +++ + +
Sbjct: 1790 KAEAAPESQPPASEDLEVDPPVAAKDKKPNKSKRSKTPVQAAAVSIVEKPVTRKSERIDR 1849
Query: 2429 EKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVK 2488
EK + G + E M +KIT + K+ +
Sbjct: 1850 EKLKRSNSPRGEAQKL-----LELKMEAEKITRTASKNSAADL----------------- 1887
Query: 2489 VDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQI----------LDPAAS 2538
E P L+RT ++ GD ++ KE +Q L AA+
Sbjct: 1888 ----EHPEPSLPLSRTRRRNVRSVYATMGDHENRSPVKEPVEQPRVTRKRLERELQEAAA 1943
Query: 2539 VTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPP------E 2592
V + R+ R K + RA E+ + + + E ++ K P E
Sbjct: 1944 VPTTPRRGRPPKTRRRADEEEENEAKEPAETLKPPEGWRSPRSQKTAAGGGPQGKKGKNE 2003
Query: 2593 LTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEG------IKVL 2646
AT + + P+ VKE + + +G ++ A D+ ++V+
Sbjct: 2004 PKVDATRPEATTEVGPQIGVKESSMEPKAAEEEAGSEQKRDRKDAGTDKNPPETAPVEVV 2063
Query: 2647 KQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDL------------AGFTELSETSGHTQE 2694
+++ + N + R R +K+ L+++ AG E + ++
Sbjct: 2064 EKKPAPEKNSKSKRGRSRNSRLAVDKSASLKNVDAAVSPRGAAAQAGERESGVVAVSPEK 2123
Query: 2695 SLTAGKATKIPCE--SPPL------EVVDTTASTKRHLRTRVQKVQVKEEP--SAVKFTQ 2744
S + K + + S P+ E D +AS T++ K E+ K +
Sbjct: 2124 SESPQKEDGLSSQLKSDPVDPDKEPEKEDVSASGPSPEATQLAKQMELEQAVEHIAKLAE 2183
Query: 2745 TSGETT---DADKEPAGEDKGIKALKESAKQTPAPAASVTGS--------RRRPRAPRES 2793
S DA + A ED+ A + S + A S+ P P ES
Sbjct: 2184 ASASAAYKADAPEGLAPEDRDKPAHQASETELAAAIGSIINDISGEPENFPAPPPYPGES 2243
Query: 2794 AQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEVKE 2853
++ AG + A +EE M D+ S LE A + RP A
Sbjct: 2244 QTDLQPPAGAQ--ALQPSEEGMETDEAV------SGILETEAATESSRPPVNAPDPSAGP 2295
Query: 2854 ELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRK-LDAEDVIGSRRQPRAPKEKA 2912
+ S ET+H+ V E KG+K + RK + SRR+ K+
Sbjct: 2296 T--DTKEARGNSSETSHS----VPEAKGSKEVEVTLVRKDKGRQKTTRSRRKRNTNKKVV 2349
Query: 2913 QPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQT-----PDSGKPLKISRRVLRAPK 2967
P+E + E +Q G + G AP++ P S P + + + P
Sbjct: 2350 APVE--SHVPESNQAQGESPAANEGTTVQHPEAPQEEKQSEKPHSTPPQSCTSDLSKIPS 2407
Query: 2968 VEPVGDVVSTRDPVKSQSKSNTSLPPLP 2995
E +S + +++ LPP P
Sbjct: 2408 TENSSQEISVEERTPTKASVPPDLPPPP 2435
Score = 50.4 bits (119), Expect = 3e-05
Identities = 209/1012 (20%), Positives = 346/1012 (34%), Gaps = 174/1012 (17%)
Query: 1427 EDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGL----KELFQTPVCTDK 1482
ED + R KQ + A S T S + P ++ +E L + KE Q P +K
Sbjct: 1551 EDSDFISGRIYGKQTSEGANSTTDSIQEPVVLFHSRFME-LTRMQQKEKEKDQKPKEVEK 1609
Query: 1483 PT---THEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMH 1539
H KT + A ++ + TP S P S + V +E AL K T K +
Sbjct: 1610 QEDTENHPKTPESAPENKDSELKTPPSVGPPS---VTVVTLESAPSALEKTT--GDKTVE 1664
Query: 1540 TPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGF---KELFQ 1596
P V+ EK V+ ++E + P E+ + ++ G KE
Sbjct: 1665 AP--LVTEEKT--------VEPATVSEEAKPASEPAPAPVEQLEQVDLPPGADPDKEAAM 1714
Query: 1597 TRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTS 1656
EE + D+ + K P + A S + + + K Q S
Sbjct: 1715 MPAGVEEGSSGDQPPYLDAKPPTPGASFSQAESNVDPEP--------DSTQPLSKPAQKS 1766
Query: 1657 GETTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIEL 1716
E EP E P D A +++ P+ + EDL
Sbjct: 1767 EEAN----EPKA---------EKPDATAD--AEPDANQKAEAAPESQPPASEDLE----- 1806
Query: 1717 FQTPSHTKESMTNE-KTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQT 1775
P K+ N+ K +K +A+ +V+ P + K + + D E+ ++
Sbjct: 1807 VDPPVAAKDKKPNKSKRSKTPVQAAAVSIVEKPVTRKSE------RIDREK----LKRSN 1856
Query: 1776 PSAGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPG-NLPGSNRRLQTRKEKAQALEELTG 1834
G+A + + EK T L+ P +LP S +TR+ +++ G
Sbjct: 1857 SPRGEAQKLLELKMEAEKITRTASKNSAADLEHPEPSLPLS----RTRRRNVRSVYATMG 1912
Query: 1835 FRELFQTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLA-- 1892
E ++P + P + T+K L + Q A T + RP ++ ++AD EEE A
Sbjct: 1913 DHEN-RSPVKE-PVEQPRVTRKRLERELQEAAAVPTTPRRGRPPKTRRRADEEEENEAKE 1970
Query: 1893 -FRKLTPSAG-KAMHTPKAAVG------EEKDINTFVGTPVEKLDLLGNLPGSKRRPQTP 1944
L P G ++ + K A G + K+ T E +G G K P
Sbjct: 1971 PAETLKPPEGWRSPRSQKTAAGGGPQGKKGKNEPKVDATRPEATTEVGPQIGVKESSMEP 2030
Query: 1945 KEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLG 2004
K A E+ ++ + T+++ + EV K P P+ K S + R + S
Sbjct: 2031 K---AAEEEAGSEQKRDRKDAGTDKNPPETAPVEVVEKKPAPE--KNSKSKRGRSRNSRL 2085
Query: 2005 KVGVKEEVLPVGKLTQTSGKTTQTHRETAG-----DGKSIKAFKE---SAKQMLDPANYG 2056
V + V G Q +G KS KE S++ DP +
Sbjct: 2086 AVDKSASLKNVDAAVSPRGAAAQAGERESGVVAVSPEKSESPQKEDGLSSQLKSDPVDPD 2145
Query: 2057 TGMERWPRTPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSP---PPESMDT 2113
E+ + + LA EL Q +H + + +P PE D
Sbjct: 2146 KEPEKEDVSASGPSPEATQLAKQMELEQAVEHIAKLAEASASAAYKADAPEGLAPEDRDK 2205
Query: 2114 PTSTRRRPKTPLGKRDIVEELS-------ALKQLTQTTHTDKVPG-------------DE 2153
P + I+ ++S A + TD P +
Sbjct: 2206 PAHQASETELAAAIGSIINDISGEPENFPAPPPYPGESQTDLQPPAGAQALQPSEEGMET 2265
Query: 2154 DKGINVFRETAK---------QKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTP 2204
D+ ++ ET DP+A T +K + + + G KE+ T
Sbjct: 2266 DEAVSGILETEAATESSRPPVNAPDPSAGPTDTKEARGNSSETSHSVPEAKGSKEVEVTL 2325
Query: 2205 ICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLA-LRKRTPSVG 2263
+ DK +KTT RS RK + ++ +A + P
Sbjct: 2326 VRKDK--GRQKTT-----------------------RSRRKRNTNKKVVAPVESHVPESN 2360
Query: 2264 KAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELF 2323
+A PA + GT VQ + P S++ TP + + +L
Sbjct: 2361 QAQG-ESPAANE--------GTTVQHPEAPQEEKQSEKPHSTPPQSCTS--------DLS 2403
Query: 2324 QTPGTDKP----TTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEE 2371
+ P T+ + +E+T A P P PA + P+ R + E
Sbjct: 2404 KIPSTENSSQEISVEERTPTKASVPPDLPPPPQPAPVDEEPQARFRVHSIIE 2455
Score = 47.4 bits (111), Expect = 2e-04
Identities = 132/667 (19%), Positives = 242/667 (36%), Gaps = 93/667 (13%)
Query: 2583 KIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEG 2642
++P S + ++ + C P + K + S +ER T+ +P +
Sbjct: 746 RLPSDSERRLYSRSSDRSGSCSSLSPPRYEKLDKSRLERYTKNEKTDKERTFDPERVERE 805
Query: 2643 IKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLE-DLAGFTELSETSGHTQESLTAGKA 2701
++++ K+K + + +R+ + +Q E D E S + L+ KA
Sbjct: 806 RRLIR---KEKVEKDKTDKQKRKGKVHSPSSQSSETDQENEREQSPEKPRSCNKLSREKA 862
Query: 2702 TKIPCESPPLEVVDTTASTKRHLR-------TRVQKVQVKEEPSAVKFTQTSGETTDADK 2754
K LE++ T+ + T V+K++ K + VK + + +
Sbjct: 863 DKEGIAKNRLELMPCVVLTRVKEKEGKVIDHTPVEKLKAKLDNDTVKSSALDQKLQVSQT 922
Query: 2755 EPAGEDKG------IKALKESAKQTPAPAASVTGSRR-----RPRAPRESAQAIEDLAGF 2803
EPA D +K KE + G + +P P + A+ DL
Sbjct: 923 EPAKSDLSKLESVRMKVPKEKGLSSHVEVVEKEGRLKARKHLKPEQPADGVSAV-DLEKL 981
Query: 2804 KDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKV-----------EVK 2852
+ + ++ +K KSSPE+ED SK++P +++V V+
Sbjct: 982 EARKRRFADSNLKAEKQKPEVKKSSPEMEDARVLSKKQPDVSSREVILLREGEAERKPVR 1041
Query: 2853 EELLA--VGKLTQTSGETTHTDKE-------PVGEGKGTKAFKQPAKRKLDAEDVIGSRR 2903
+E+L K+ T + K+ VG G + Q +L E V
Sbjct: 1042 KEILKRESKKIKLDRLNTVASPKDCQELASISVGSGSRPSSDLQARLGELAGESVENQEV 1101
Query: 2904 QPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKPLKISRRVL 2963
Q + P L+ L + Q P + N + S +TP+ + S V
Sbjct: 1102 QSKKPIPSKPQLKQLQVLDD--QGPEREDVRKN-----YCSLRDETPERKSGQEKSHSVN 1154
Query: 2964 RAPKVE-PVGDVVSTRDPVK-SQSKSNTSLPPLPFKRGGGKDGSVTGTKRLRCM----PA 3017
K+ + S R ++ S+ K + ++ G V +R +
Sbjct: 1155 TEEKIGIDIDHTQSYRKQMEQSRRKQQMEMEIAKSEKFGSPKKDVDEYERRSLVHEVGKP 1214
Query: 3018 PEEIVEELPASKKQRV--------APRARGKSSEPVVIMKRSLRTSAKRI-------EPA 3062
P+++ ++ P SKK+R+ R R S I + S RT E
Sbjct: 1215 PQDVTDDSPPSKKKRMDHVDFDICTKRERNYRSSR-QISEDSERTGGSPSVRHGSFHEDE 1273
Query: 3063 EELNSNDMKTNKEEHKLQDSVPENKGISLR-----------SRRQNKTEAEQQITEVFVL 3111
+ + S + + K K+ + V I++R SRR+ A+ ++ VL
Sbjct: 1274 DPIGSPRLLSVKGSPKVDEKVLPYSNITVREESLKFNPYDSSRREQM--ADMAKIKLSVL 1331
Query: 3112 AERIEINRNEKKPMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAE 3171
E+NR + + + + D+ P+ I RD + KR +R E P ++
Sbjct: 1332 NSEDELNRWDSQMKQDAGRFDVSFPN----SIIKRDSL--RKRSVRDLEPGE--VPSDSD 1383
Query: 3172 ESGGQKS 3178
E G KS
Sbjct: 1384 EDGEHKS 1390
Score = 35.0 bits (79), Expect = 1.2
Identities = 170/872 (19%), Positives = 308/872 (35%), Gaps = 126/872 (14%)
Query: 779 NSENLLGKQFQGTDSGEEPLLPTSESFGGNVFFSAQNAAKQPSDKCSAS------PPLRR 832
+S L K Q ++ EP ++ + Q A P + AS PP+
Sbjct: 1754 DSTQPLSKPAQKSEEANEPKAEKPDATADAEPDANQKAEAAPESQPPASEDLEVDPPVAA 1813
Query: 833 QCIRENGNV-AKTPRNTYKMTSLETKTSDTETEPSKTVSTANRSGRSTEFRNIQKLPVES 891
+ + N + +KTP ++ +E + + + S R E + + +L +E+
Sbjct: 1814 KDKKPNKSKRSKTPVQAAAVSIVEKPVTRKSERIDREKLKRSNSPRG-EAQKLLELKMEA 1872
Query: 892 -KSEETNTEIVECILKRGQKATLLQQRREGEMKEIERPFETYKENIELKENDEKMKAMKR 950
K T ++ L+ + + L + R ++ + ++ +KE E+ + ++
Sbjct: 1873 EKITRTASKNSAADLEHPEPSLPLSRTRRRNVRSVYATMGDHENRSPVKEPVEQPRVTRK 1932
Query: 951 SRTWGQKCAPMSDLTDLKSLP-------DTELMKDTARGQNLLQTQDHAKAPKSEKGKIT 1003
+ A T + P D E + L+ + ++P+S+K
Sbjct: 1933 RLERELQEAAAVPTTPRRGRPPKTRRRADEEEENEAKEPAETLKPPEGWRSPRSQKTAAG 1992
Query: 1004 KMPCQSLQPEPINTPTHTKQQLKASLG-KVGVKEELLAVGKFTRTSGETTHTHREPAGDG 1062
P Q + + T+ + +G ++GVKE + +G R+ AG
Sbjct: 1993 GGP-QGKKGKNEPKVDATRPEATTEVGPQIGVKESSMEPKAAEEEAGSEQKRDRKDAGTD 2051
Query: 1063 KS------IRTFKESPKQILDPAARVTGMKKWPRTPKEEAQSLEDL------------AG 1104
K+ + ++ P + ++ G + R +++ SL+++ AG
Sbjct: 2052 KNPPETAPVEVVEKKPAPEKNSKSK-RGRSRNSRLAVDKSASLKNVDAAVSPRGAAAQAG 2110
Query: 1105 FKELFQTPGPSEESMTDEKTTKIAC--KSPP------PESVDTPTSTKQWPKRSLRKA-D 1155
+E E+S + +K ++ KS P PE D S L K +
Sbjct: 2111 ERESGVVAVSPEKSESPQKEDGLSSQLKSDPVDPDKEPEKEDVSASGPSPEATQLAKQME 2170
Query: 1156 VEEEFLALRKLTPSAGKAM--------LTP----KPAG-GDEKDIKAFMGTPVQKLDLAG 1202
+E+ + KL ++ A L P KPA E ++ A +G+ + D++G
Sbjct: 2171 LEQAVEHIAKLAEASASAAYKADAPEGLAPEDRDKPAHQASETELAAAIGSIIN--DISG 2228
Query: 1203 T---------LPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPCDS 1253
PG + P AQAL+ E + E AA ++++ P ++
Sbjct: 2229 EPENFPAPPPYPGESQTDLQPPAGAQALQPSEEGMETDEAVSGILETEAATESSRPPVNA 2288
Query: 1254 PQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFV 1313
P DP PT TK+ + G + T SV E K
Sbjct: 2289 P--DPSAGPTDTKE-----------------------ARGNSSETSH-SVPEAKGSKEVE 2322
Query: 1314 GTPVQKLDLTENLTGSKRRPQTPKEEAQALEDLTGFKELFQ--TPGHTE-------EAVA 1364
T V+K + T S+R+ T K+ +E Q +P E EA
Sbjct: 2323 VTLVRKDKGRQKTTRSRRKRNTNKKVVAPVESHVPESNQAQGESPAANEGTTVQHPEAPQ 2382
Query: 1365 AGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVP 1424
K ++ P S+PP+S + S + P T +++ E K + P
Sbjct: 2383 EEKQSEKP-HSTPPQSCTSDLS--KIPSTENSSQEISVEERTPTKASVPPDLPPPPQPAP 2439
Query: 1425 GGEDKSINAFRETAKQKLDPAA-----SVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVC 1479
E+ FR + + DP S+ T K P G+
Sbjct: 2440 VDEEPQAR-FRVHSIIESDPVTPPSDPSIPIPTLPSVTAAKLSPPVASGGIPHQSPPTKV 2498
Query: 1480 TDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTP------- 1532
T+ T E+ + S P DT S S +LRK+ ++ ++ + T
Sbjct: 2499 TEWITRQEEPRAQSTPSPALPPDTKASDVDTSSSTLRKILMDPKYVSATSVTSTSVTTAI 2558
Query: 1533 ----SAGKAMH-TPKPAVSGEKNIYAFMGTPV 1559
SA +H P P V +K + PV
Sbjct: 2559 AEPVSAAPCLHEAPPPPVDSKKPLEEKTAPPV 2590
Score = 34.7 bits (78), Expect = 1.6
Identities = 42/190 (22%), Positives = 82/190 (43%), Gaps = 31/190 (16%)
Query: 3035 PRARGKSSEPVVIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSR 3094
P+ +G SS V+ K + K ++P + + S + + + R R
Sbjct: 940 PKEKGLSSHVEVVEKEGRLKARKHLKPEQPADGV-------------SAVDLEKLEARKR 986
Query: 3095 R--QNKTEAEQQITEVFVLAERIEINR--NEKKPMKTSPEMDIQNPDDGARKPIPRDKVT 3150
R + +AE+Q EV + +E R ++K+P +S E+ + + RKP+ ++ +
Sbjct: 987 RFADSNLKAEKQKPEVKKSSPEMEDARVLSKKQPDVSSREVILLREGEAERKPVRKEILK 1046
Query: 3151 ENKRCLRSARQNESSQPKVAEESGGQKSAKVLMQNQKGKGEAGNSDSMCLRSRKTKSQPA 3210
+ ++ R N + PK +E L G G +SD L++R + A
Sbjct: 1047 RESKKIKLDRLNTVASPKDCQE---------LASISVGSGSRPSSD---LQAR--LGELA 1092
Query: 3211 ASTLESKSVQ 3220
++E++ VQ
Sbjct: 1093 GESVENQEVQ 1102
Score = 34.3 bits (77), Expect = 2.1
Identities = 88/445 (19%), Positives = 157/445 (35%), Gaps = 52/445 (11%)
Query: 1662 THTEPTGD--GKSMKAFMESPKQI-LDSAASLTGSKRQLRTPKG-KSEVPEDLAGFIELF 1717
+ TEP K M+ PK+ L S + + +L+ K K E P D ++L
Sbjct: 920 SQTEPAKSDLSKLESVRMKVPKEKGLSSHVEVVEKEGRLKARKHLKPEQPADGVSAVDLE 979
Query: 1718 QTPSHTK---ESMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQ 1774
+ + + +S + K + S P++ D SK QP S R+ E A RK
Sbjct: 980 KLEARKRRFADSNLKAEKQKPEVKKSSPEMEDARVLSKKQPDVSSREVILLREGEAERKP 1039
Query: 1775 TPSAGKAMHTPK------PAVGEEKDINTFLGTPVQKLDQP--------GNLPGSNRRLQ 1820
+ K V KD V +P G L G +
Sbjct: 1040 VRKEILKRESKKIKLDRLNTVASPKDCQELASISVGSGSRPSSDLQARLGELAGES---- 1095
Query: 1821 TRKEKAQALEELTGFRELFQTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRPKRS 1880
++ Q+ + + +L Q D+ + + +K C P K +
Sbjct: 1096 VENQEVQSKKPIPSKPQLKQLQVLDDQGPEREDVRKNYCSLRDETPERKSGQEKSHSVNT 1155
Query: 1881 LKKADVE-EEFLAFRK-LTPSAGKAMHTPKAAVGE-----EKDINTF--------VGTPV 1925
+K ++ + ++RK + S K + A E +KD++ + VG P
Sbjct: 1156 EEKIGIDIDHTQSYRKQMEQSRRKQQMEMEIAKSEKFGSPKKDVDEYERRSLVHEVGKPP 1215
Query: 1926 EKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQ 1985
+ D+ + P SK++ + + ++ Q +E + + S +
Sbjct: 1216 Q--DVTDDSPPSKKKRMDHVDFDICTKRERNYRSSRQISEDSERTGGSPSVRHGSFHEDE 1273
Query: 1986 PDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFKES 2045
DP+ +P RL G V E+VLP +T ++ + D + +
Sbjct: 1274 -DPIGSP-----RLLSVKGSPKVDEKVLPYSNITVRE----ESLKFNPYDSSRREQMADM 1323
Query: 2046 AKQMLDPANYGTGMERWPRTPKEEA 2070
AK L N + RW K++A
Sbjct: 1324 AKIKLSVLNSEDELNRWDSQMKQDA 1348
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 61.6 bits (148), Expect = 1e-08
Identities = 301/1472 (20%), Positives = 493/1472 (33%), Gaps = 236/1472 (16%)
Query: 1911 VGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKAKALEDLAGFKELFQTPGHTEES 1970
V E+ F+ PV LD+ + + + K KA+ L K P T ES
Sbjct: 30 VKEQSGQKCFLAQPVTLLDIYTHWQQTSELGR--KRKAEEDAALQAKKTRVSDPISTSES 87
Query: 1971 MTDDKITEVSCKSPQPDPVKT---------PTSSKQRLKISLGKVGVKEEVLP---VGKL 2018
+++ E P T P+S K++ K K G +P GK
Sbjct: 88 SEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKT 147
Query: 2019 TQT--SGKTTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDL 2076
SGK+ R++A + E+ ++ PA +G + + + S ED
Sbjct: 148 VANLLSGKSP---RKSAEPSANTTLVSETEEEGSVPA-FGAAAKPGMVSAGQADSSSEDT 203
Query: 2077 AGFKELFQTPDHTE-ESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEELS 2135
+ + D T+ E +K ++ S P + +T P P + +
Sbjct: 204 SS------SSDETDVEVKASEKILQVRAASAPAKGTPGKGAT---PAPPGKAGAVASQTK 254
Query: 2136 ALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGS-----KRQPR-----TPK 2185
A K + + + D ++ + + K S G+ K PR P
Sbjct: 255 AGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPP 314
Query: 2186 GKAQPL--EDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSL 2243
GK P + AG +E D ++ E++ Q P G
Sbjct: 315 GKTGPAVAKAQAGKRE-------EDSQSSSEESDSEEEAPAQAKPSG------------- 354
Query: 2244 RKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWP 2303
KA + A K +P G A P+ G ++ +G + S R
Sbjct: 355 -KAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQ--VGKQEEDSRSSSEESDSDR-- 409
Query: 2304 QTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRN 2363
+A A + A K L ++P +T P P PA+ P
Sbjct: 410 -----EALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPAT----PSAQ 460
Query: 2364 LRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQ 2423
+ K + + E + S G+ PA EK++ ++ G P K
Sbjct: 461 VGKWEEDSESSSEESSDSSDGEVPTAVAPA--QEKSLGNILQAKPTSSPAKG--PPQKAG 516
Query: 2424 PQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLK 2483
P + KAE D + E +D S S + + T+ +K LK
Sbjct: 517 PVAVQVKAEKPMD----------NSESSEESSD------SADSEEAPAAMTAAQAKPALK 560
Query: 2484 IPLVKVDMKEEPLAVSKLTRTSGETTQ------THTEPTGDSKSIKAFKESP------KQ 2531
IP K K+ S TQ T T P G S ++ + P +
Sbjct: 561 IPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSE 620
Query: 2532 ILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSA---------PGHTEESMTIDKNT 2582
D TG + K + L+ + + PG T ++T K
Sbjct: 621 ESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAE 680
Query: 2583 KIPCKSPPPELTDT--ATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGD 2640
K E +D+ A ++ KT +K + A R G T P
Sbjct: 681 KQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKG----TISAPGKVV 736
Query: 2641 EGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGK 2700
KQR+ K P P A + P A T +G ++S ++ +
Sbjct: 737 TAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEE 796
Query: 2701 ATKIPCESPPLEVVDTTASTKRHLRT---RVQKVQVKEEPSAVKFTQTSGETTDADKEPA 2757
ES E +T A K +T R KE P G+T + +
Sbjct: 797 ------ESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAG 850
Query: 2758 GEDKGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTD 2817
+D + +ES APAA SAQ I+ F DP + T
Sbjct: 851 KQDDSGSSSEESDSDGEAPAAVT------------SAQVIKPPLIFVDPNRSPAGPAATP 898
Query: 2818 DKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEV--KEELLAVGKLTQT-SGETTHTDKE 2874
+ S+P + S+ R + ++ +V + L G T + T H
Sbjct: 899 ---AQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIA 955
Query: 2875 PVGEGKGTKAFKQPAK----RKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGH 2930
P G + K+ ++ +K + S++ P + L+ LA +Q P
Sbjct: 956 PKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVA 1015
Query: 2931 TEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTS 2990
+ ++G + + P +P S LR PK+ V +T+ P S ++S
Sbjct: 1016 RTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQ--ATKAPESSDDSEDSS 1073
Query: 2991 LPPLPFKRGGGKDG-SVTGTKRLRCM-PAP---EEIVEELPA--SKKQRVAPR---ARGK 3040
G +DG G K + P P E +VEE A S+ VAP G
Sbjct: 1074 ----DSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGY 1129
Query: 3041 SSEPVVIMKRSLRTSAKRIEPAEELNS----NDMKTNKEEHKLQDSV----PENKG---- 3088
+ + + +++ + ++S D K+E K Q + P+ G
Sbjct: 1130 MTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAA 1189
Query: 3089 ---ISLRSRRQNK---------------------------TEAEQQITEVFVLAERIEIN 3118
+SR+ K EA+ Q + V VL E +E
Sbjct: 1190 SGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQE 1249
Query: 3119 RNEKKPMKTSPEMDIQNPDDGARK-----PIPRDKVTENKRCLRSARQNES--SQPKVAE 3171
R KK + T+ E + + RK P R ++ K+ L + E+ S K +
Sbjct: 1250 R--KKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTST 1307
Query: 3172 ESGG---QKSAKVLMQNQKGKGEAGNSDSMCLRSRKTKSQPAASTLES------KSVQRV 3222
S G + A ++ +KGKG G+ + + + Q T+E KS +
Sbjct: 1308 TSKGKAKRDKASGDVKEKKGKGSLGSQGAK--DEPEEELQKGMGTVEGGDQSNPKSKKEK 1365
Query: 3223 TRSVKRCAENPKKAEDNVCVKKIRTRSHRDSE 3254
+S KR + KK + KK + S +DSE
Sbjct: 1366 KKSDKRKKDKEKKEKK----KKAKKASTKDSE 1393
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 60.8 bits (146), Expect = 2e-08
Identities = 386/1988 (19%), Positives = 613/1988 (30%), Gaps = 275/1988 (13%)
Query: 1017 TPTHTKQQLKASLGKVGVKEELLAVGKFTRTS-GETTHTHREPAGDGKSIR----TFKES 1071
T + Q+ AS G E L+ G T +S G+ + T GD ++ T
Sbjct: 3045 TTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSG 3104
Query: 1072 PKQILDPAARVTGMKKWPRTP--------KEEAQSLEDLAGFKELFQTPGPSEESMTDEK 1123
+ P TG TP +EE+ + + + +P + + +
Sbjct: 3105 LVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVS 3164
Query: 1124 TTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEE--------FLALRKLTPSAGKAML 1175
TT + S P + + +ST RS V F + G+
Sbjct: 3165 TTYHSRPSSTPTTHFSASSTTLG--RSEESTTVHSSPGATGTALFPTRSATSVLVGEPTT 3222
Query: 1176 TPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGFKELFQT-- 1233
+P +G E T + + T S R T A +G E T
Sbjct: 3223 SPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTS--SGVSEESTTSH 3280
Query: 1234 --PGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMPS 1291
PG T G TT + +P ST A G + P
Sbjct: 3281 SRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPG 3340
Query: 1292 AGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALEDLTGFKE 1351
+ + P + ++ TPV + + T S T + E+ + K+
Sbjct: 3341 STETTLLPDNTTASG---LLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKD 3397
Query: 1352 LFQTPGHTEEAVAAGKTTKMPCESSPPE---SADTPTSTRRQPKTPLEKRDVQKELSALK 1408
P T A TT SS P SA + T R + T + V +
Sbjct: 3398 TTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSP 3457
Query: 1409 KLTQTSG---ETTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLE 1465
+ TSG E+T PG + + P + T + T +
Sbjct: 3458 ARSTTSGLVEESTTYHSSPG-----------STQTMHFPESDTTSGRGEESTTSHSSTTH 3506
Query: 1466 DLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFF 1525
++ T ++PT++ + + T + +S S D
Sbjct: 3507 TISSAPST--TSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIV 3564
Query: 1526 ALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQAL 1585
+ T S T P SG A G+ L+E T +P+ A L
Sbjct: 3565 LPARSTTSVLLGESTTSPISSGSMETTALPGSTTTP-GLSEKSTTFH---SSPRSPATTL 3620
Query: 1586 EDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEE 1645
+ + G +EES T+ ++ PD P S R TS G +
Sbjct: 3621 SPAST-----TSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLS-RHSTTSHSSPGSTDT 3674
Query: 1646 LLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASLT------GSKRQLRT 1699
L T TSG + + T + G + A L T GS
Sbjct: 3675 TLLPASTT-TSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLF 3733
Query: 1700 PKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQPDLVDTPTSSKPQPKR-- 1757
P + +G +E + S + +TT ++ P L T+ + P
Sbjct: 3734 PDSTTS-----SGIVE---ASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTH 3785
Query: 1758 ------SLRKADTEEEFLAFRKQTPSAGKAMHTPKPAV--GEEKDINTFLGTPVQKLDQP 1809
S A EE R +P + H P + G + F +P D
Sbjct: 3786 TTPSPPSTATAPVEESTTYHR--SPGSTPTTHFPASSTTSGHSEKSTIFHSSP----DAS 3839
Query: 1810 GNLPGSNRRLQTRKEKAQALEELTGFRELFQTP-CTDNPTTDEKTTKKILCKSPQSDPAD 1868
G P S + + ++ G E+ P T P E +T SP+S
Sbjct: 3840 GTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTT--FYSSPRS---- 3893
Query: 1869 TPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAVGEEKDINTFVGTPVEKL 1928
PT T S+ V EE R P + + +P + T G E
Sbjct: 3894 -PTTTLS--PASMTSLGVGEESTTSRS-QPGSTHSTVSPAST--------TTPGLSEEST 3941
Query: 1929 DLLGNLPGSKRRPQTPKEKAKAL--EDLAGFKEL---FQTPGHTEESMTDDKITEVSCKS 1983
+ + PGS P+ ++ E+ F T TE+S T +TE S
Sbjct: 3942 TVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSG-LTEESTAF 4000
Query: 1984 PQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFK 2043
P +P S++ L +L + EE + ++G R T
Sbjct: 4001 PG-----SPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSG-----LVG 4050
Query: 2044 ESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQTPDHT------------EE 2091
ES L P++ T P +P + S E F ++PD T EE
Sbjct: 4051 ESTPSRLSPSS--TETTTLPGSPTTPSLS-EKSTTFYTSPRSPDATLSPATTTSSGVSEE 4107
Query: 2092 STTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVEEL--------SALKQLTQT 2143
S+T + P+S T + + P T + E S+L Q + T
Sbjct: 4108 SSTSHSQPGSTHTTAFPDSTTT-SGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTT 4166
Query: 2144 THTDKVPGDEDKGI---NVFRETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKE- 2199
H+ PGD + + + + P S TGS TP GL+E
Sbjct: 4167 FHSS--PGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTS-----TGLQEE 4219
Query: 2200 --LFQT-PICTDKPTTHEKTTKIACR---SPQPDPVGTPTIFKPQSKRSLRKADVEEESL 2253
FQ+ P +D + TT + + P TPT S +L ++ EES
Sbjct: 4220 STTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRS---EEST 4276
Query: 2254 ALRKRTPSVGKAMDTPKPAGG---DEKDMKAFMGTPVQKLDLPGNLP------------G 2298
+ + G A+ + A E + LPG+
Sbjct: 4277 TVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYS 4336
Query: 2299 SKRWPQTPKEKAQALEDLAGFKELFQT----PG----------TDKPTTDEKTTKIACKS 2344
S R P T A +G E T PG T P +++T
Sbjct: 4337 SPRSPDTTLSPASTTS--SGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSP 4394
Query: 2345 PQPD----PVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKNI 2400
D P T AS+ + E L T ++G ++ P S +
Sbjct: 4395 GSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASG-LLEASTPVHSSTGSP 4453
Query: 2401 NTFVE-----TPVQKLDLLGNLPGSKRQPQTPKEKAEALEDL-------------VGFKE 2442
+T + T + + P SK P A +L F
Sbjct: 4454 HTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSA 4513
Query: 2443 LFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLT 2502
T G +EES T + +P P TS ++ + S T
Sbjct: 4514 SSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTT 4573
Query: 2503 RTSGE------TTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRT---RKEKA 2553
GE ++ THT + S + +E P ++ T T R E++
Sbjct: 4574 SGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEES 4633
Query: 2554 RALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKS------------PPPELTDTATSTK 2601
A D P + S+ + ++T P S P L++ +T+
Sbjct: 4634 TASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFH 4693
Query: 2602 RCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEP 2661
P + P + + R S +ST H P + P+P
Sbjct: 4694 SSPSSTPTTHFSASSTTLGR----SEESTTVHSSPVA-----------TATTPSPARSTT 4738
Query: 2662 SRRRPRAPKEKAQP-LEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTAST 2720
S + + P F E S SG ++ES T+ +T SPP
Sbjct: 4739 SGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPP-STTSALVEE 4797
Query: 2721 KRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKAL----------KESA 2770
+ + P + + S E+T + P + GI L ES
Sbjct: 4798 PTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSP--DTNGITPLPAHFTTSGRIAEST 4855
Query: 2771 KQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPE 2830
+P + T P SA++ + + P + SMT + P +
Sbjct: 4856 TFYISPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQ 4915
Query: 2831 LEDTATSS 2838
E T T++
Sbjct: 4916 AESTHTTA 4923
Score = 59.7 bits (143), Expect = 5e-08
Identities = 378/1883 (20%), Positives = 595/1883 (31%), Gaps = 222/1883 (11%)
Query: 1017 TPTHTKQQLKASLGKVGVKEELLAVGKFTRTS--GETTHTHREPAGDGKSIRTFKESPKQ 1074
T + Q+ S G + L+ G T S E+T H P ++ +
Sbjct: 2599 TTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSG 2658
Query: 1075 ILDPAARVTGMKKWPRTPKEEAQSLED-LAGFKELFQTPGPSEESMTDEKTTKIACKSPP 1133
I++ + RV PRT A S L G FQT S + +T A
Sbjct: 2659 IVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEES 2718
Query: 1134 PESVDTP--TSTKQWPKRSLRKADVEEEFLALRK-----LTPSAGKAMLTPKPAGGDEKD 1186
+P T T +P S E+ + TPS+ + + + G+
Sbjct: 2719 TTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGR---GESTT 2775
Query: 1187 IKAFMG-TPVQKLDLAGTLPGSKRQLQT----PKEKAQALEDLA----GFKELFQT---- 1233
+ G T + L + T PG T P+ L + G E T
Sbjct: 2776 SRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQ 2835
Query: 1234 PGHTEELVAAGKTTKIPCDSPQSDPV--DTPTSTKQRPKRSIRKADVEGELLACRNLMPS 1291
PG T V+ TT P S +S V +P ST+ V GE + P+
Sbjct: 2836 PGSTHSTVSPASTTT-PGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPA 2894
Query: 1292 AGKAMHTPKPSV--GEEKDIIIFVGTPVQ-KLDLTENLTGSKRRPQTPKEEAQALEDLTG 1348
+ + S G ++ F G+P + L LT + EE+ +G
Sbjct: 2895 STHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLG-----EESTTFPSSSG 2949
Query: 1349 FKELFQTPGHTEEAVAAGK------------TTKMPCESSPPESADTPTSTRRQPKTP-- 1394
+P + + G+ TT +P + P ++ T+ P++P
Sbjct: 2950 STGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDA 3009
Query: 1395 ------LEKRDVQKELS------------ALKKLTQTSG---ETTHTDKVPGGEDKSINA 1433
V +E S A T TSG E T + G + +++
Sbjct: 3010 TLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSP 3069
Query: 1434 FRETAKQKLDPAASVTGSKRHPKTK------------EKAQPLEDLAGLKELFQTPVCTD 1481
TA + + S +T E + P G TP +
Sbjct: 3070 GSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASST 3129
Query: 1482 KPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTP 1541
E++T +S P DT T S P + + V+V + + TP+ + +
Sbjct: 3130 SAGLQEESTTF--QSWPSSSDT-TPSPPGTTAA--PVEVSTTYHSRPSSTPTTHFSASST 3184
Query: 1542 KPAVSGEKN-IYAFMGTPVQKLDLTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGH 1600
S E +++ G L T + T T + +G E G
Sbjct: 3185 TLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPIS------SGSTETTALPGS 3238
Query: 1601 TEESMTNDKTAKVACKSSQPDPDKNPASS-----KRRLKTSLGKVGVKEELLAVGKLTQ- 1654
T + ++K+ PD +PAS+ TS + G G T
Sbjct: 3239 TTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMP 3298
Query: 1655 -TSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGKSE---VPEDL 1710
S E+T +H+ P ++ SP +A+SL + G +E +P++
Sbjct: 3299 GVSQESTASHSSPGSTDTTL-----SPGST--TASSLGPESTTFHSGPGSTETTLLPDNT 3351
Query: 1711 --AGFIELFQTPSHTKESMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEF 1768
+G +E TP H S T T +S S ++ T + A
Sbjct: 3352 TASGLLEA-STPVH---SSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTS 3407
Query: 1769 LAFRKQTPSAGKAMHTP-------KPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQT 1821
T S G TP +G ++ T +PV P + L
Sbjct: 3408 AFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLV- 3466
Query: 1822 RKEKAQALEELTGFRELFQTPCTDNP-------TTDEKTTKKILCKSPQSDPA--DTPTN 1872
E++ G + P +D TT +T + +P + A + PT+
Sbjct: 3467 --EESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTS 3524
Query: 1873 TKQRPKR--------SLKKADVEEEFLAFRKLTPSAGK----AMHTPKAAVGEEKDINTF 1920
P S + EE A + G A T +GE
Sbjct: 3525 YHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPIS 3584
Query: 1921 VGTPVEKLDLLGNL--PGSKRRPQT----PKEKAKALEDLAGFKELFQTPGHTEESMTDD 1974
G+ +E L G+ PG + T P+ A L + + G +EES T
Sbjct: 3585 SGS-METTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPAST-----TSSGVSEESTTSH 3638
Query: 1975 KITEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGKTTQTHRETAG 2034
+ + PD TP S+ +LP T TSG + ++ +
Sbjct: 3639 SRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAS--TTTSGSSQESTTSHSS 3696
Query: 2035 DGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSL-EDLAGFKELFQTPDHTEEST 2093
G + A + L ++G + +P +L D + + ST
Sbjct: 3697 SGSTDTALSPGSTTAL---SFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSST 3753
Query: 2094 TDDKTTKIACKSPPP----ES---MDTPTSTRRRPKTPLGKRDIVEELSALKQLTQTTHT 2146
+TT S P ES P ST P P VEE + + +T T
Sbjct: 3754 GSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPT 3813
Query: 2147 DKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTP-KGKAQPLEDLAGLKELFQTPI 2205
P + + T A+ T S T +G++ G E+ P
Sbjct: 3814 THFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPG 3873
Query: 2206 CTDKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKA 2265
T P E +T P T P S SL V EES R + G
Sbjct: 3874 STTTPGLSEASTTF-----YSSPRSPTTTLSPASMTSL---GVGEESTTSRSQP---GST 3922
Query: 2266 MDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQAL--EDLAGFKELF 2323
T PA G + + + PGS P+ ++ E+ F
Sbjct: 3923 HSTVSPAS------TTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRP 3976
Query: 2324 QTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSA 2383
+ T T D T+ + +S +PAST+ L AD+ EE + S
Sbjct: 3977 ASTHTTLFTEDSTTSGLTEESTAFP--GSPASTQTGLPATLTTADLGEESTTFPSSSGST 4034
Query: 2384 GKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKEL 2443
G + + S +T + LPGS P EK+ +
Sbjct: 4035 GTKLSPARSTTSGLVGESTPSRLSPSSTETT-TLPGSPTTPSL-SEKSTTFYTSPRSPDA 4092
Query: 2444 FQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTR 2503
+P T S + E S QP S T+ + +EP S ++
Sbjct: 4093 TLSPATTTSSGVSE---ESSTSHSQPGSTHTTAFPDS-----TTTSGLSQEP-TTSHSSQ 4143
Query: 2504 TSGETTQTHTEPTGDS--KSIKAFKESP---KQILDPAASVTGSRRQLRTRKEKARALED 2558
S E T + T S + F SP + L P ++T + T +
Sbjct: 4144 GSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLH 4203
Query: 2559 LVDFKELFSAPGHTEESMTIDKNTKIPCKSP-PPELTDTATSTKRCPKTRPRKEVKEELS 2617
++ G EES T +P PP T +RP S
Sbjct: 4204 TTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFS 4263
Query: 2618 AVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLE 2677
A S +ST H P G G + R+ + + EP+ + + L
Sbjct: 4264 ASSTTLGRSEESTTVHSSP--GATGTALFPTRS--ATSVLVGEPTTSPISSGSTETTALP 4319
Query: 2678 DLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEP 2737
LSE S S + T P + V + ST H +R + P
Sbjct: 4320 GSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGV--SEESTTSH--SRPGSMHTTAFP 4375
Query: 2738 SAVKFTQTSGETTDADKEPAGED 2760
S+ S E+T + P D
Sbjct: 4376 SSTTMPGVSQESTASHSSPGSTD 4398
Score = 52.4 bits (124), Expect = 7e-06
Identities = 439/2191 (20%), Positives = 670/2191 (30%), Gaps = 312/2191 (14%)
Query: 983 QNLLQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPTHTKQQLKASLGKVGVKEELLAVG 1042
Q+ ++D + AP K+ + P +TPT +LG
Sbjct: 422 QSWPSSKDTSPAPSGTTSAFVKLST-TYHSSPSSTPTTHFSASSTTLGH----------- 469
Query: 1043 KFTRTSGETTHTHREPAGDGKSIRTFKESPKQILDPAARVTGMKKWPRTPKEEAQSLEDL 1102
S E+T H P + T P PA T T +
Sbjct: 470 -----SEESTPVHSSP------VATATTPP-----PARSATSGHVEESTAYHRSPGSTQT 513
Query: 1103 AGFKELFQTPGPSEESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLA 1162
F E T G SEES T +T S TP++T S + E
Sbjct: 514 MHFPESSTTSGHSEESATFHGSTTHTKSS-------TPSTTAALAHTSYHSSLGSTETTH 566
Query: 1163 LRKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALE 1222
R + +G++ A D A P AG+ P TP +
Sbjct: 567 FRDSSTISGRS--EESKASHSSPDAMATTVLP------AGSTPSVLVGDSTPSPISSGSM 618
Query: 1223 DLAGFKELFQTPGHTEELVA------AGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKA 1276
+ PG +E+ + TT +P S + T++ RP + A
Sbjct: 619 ETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTA 678
Query: 1277 DVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTP 1336
MP + S G + T L E T R T
Sbjct: 679 ------FPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLG-PEYTTFHSRPGST- 730
Query: 1337 KEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADT-----PTSTRRQP 1391
E L D T L + + + TT P S+ + T P+S +P
Sbjct: 731 --ETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRP 788
Query: 1392 KTPLEKRDVQKELSALKKLTQTSGETTHTD--KVPGG---EDKSINAFRETAKQKLDPAA 1446
P E S + +S TTH G E + ++ + + P +
Sbjct: 789 APPTTT-SAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPES 847
Query: 1447 SVTGSKRHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTS 1506
T + T + ++ T ++PT++ + + T +
Sbjct: 848 DTTSGRGEESTTSHSSTTHTISSAPST--TSALVEEPTSYHSSPGSTATTHFPDSSTTSG 905
Query: 1507 SKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTE 1566
+S S D + T S T P SG A G+ L+E
Sbjct: 906 RSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTP-GLSE 964
Query: 1567 NLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNP 1626
T +P+ A L + + G +EES T+ ++ PD P
Sbjct: 965 RSTTFH---SSPRSPATTLSPAST-----TSSGVSEESTTSRSRPGSTHTTAFPDSTTTP 1016
Query: 1627 ASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDS 1686
S R TS G + L T TSG + + T + G + A L
Sbjct: 1017 GLS-RHSTTSHSSPGSTDTTLLPASTT-TSGPSQESTTSHSSSGSTDTALSPGSTTALSF 1074
Query: 1687 AASLT------GSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRAS 1740
T GS P + +G +E + S + +TT ++
Sbjct: 1075 GQESTTFHSNPGSTHTTLFPDSTTS-----SGIVE---ASTRVHSSTGSPRTTLSPASST 1126
Query: 1741 QPDLVDTPTSSKPQPKR--------SLRKADTEEEFLAFRKQTPSAGKAMHTPKPAV--G 1790
P L T+ + P S A EE R +P + H P + G
Sbjct: 1127 SPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHR--SPGSTPTTHFPASSTTSG 1184
Query: 1791 EEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTP-CTDNPTT 1849
+ F +P D G P S + + ++ G E+ P T P
Sbjct: 1185 HSEKSTIFHSSP----DASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGL 1240
Query: 1850 DEKTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKA 1909
E +T SP+S PT T S+ V EE R P + + +P +
Sbjct: 1241 SEASTT--FYSSPRS-----PTTTLS--PASMTSLGVGEESTTSRS-QPGSTHSTVSPAS 1290
Query: 1910 AVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKAKAL--EDLAGFKEL---FQTP 1964
T G E + + GS P ++ E+ F T
Sbjct: 1291 T--------TTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTT 1342
Query: 1965 GHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKEEVLPVGKLTQTSGK 2024
TE+S T +TE S P +P S++ L +L + EE + ++G
Sbjct: 1343 LFTEDSTTSG-LTEESTAFPG-----SPASTQTGLPATLTTADLGEESTTFPSSSGSTGT 1396
Query: 2025 TTQTHRETAGDGKSIKAFKESAKQMLDPANYGTGMERWPRTPKEEAQSLEDLAGFKELFQ 2084
R T ES L P++ T P +P + S E F +
Sbjct: 1397 KLSPARSTTSG-----LVGESTPSRLSPSS--TETTTLPGSPTTPSLS-EKSTTFYTSPR 1448
Query: 2085 TPDHT------------EESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDIVE 2132
+PD T EES+T + P+S T + + P T + E
Sbjct: 1449 SPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTT-SDLSQEPTTSHSSQGSTE 1507
Query: 2133 EL--------SALKQLTQTTHTDKVPGDEDKGI---NVFRETAKQKLDPAASVTGSKRQP 2181
S+L Q + T H+ PGD + + + + P S TGS
Sbjct: 1508 ATLSPGSTTASSLGQQSTTFHSS--PGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTT 1565
Query: 2182 RTPKGKAQPLEDLAGLKE---LFQT-PICTDKPTTHEKTTKIACR---SPQPDPVGTPTI 2234
TP AGL+E FQ+ P +D + TT + P TPT
Sbjct: 1566 LTPASSTS-----AGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTT 1620
Query: 2235 FKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPG 2294
S +L ++ EES + + G A+ + A +G P
Sbjct: 1621 HFSASSTTLGRS---EESTTVHSSPGATGTALFPTRSA------TSVLVGEPTTS----- 1666
Query: 2295 NLPGSKRWPQTPKEKAQALEDLAGFKELFQTPG-TDKPTTDEKTTKIACKSPQPDPVDTP 2353
P S +G E PG T EK+T PD +P
Sbjct: 1667 --PIS-----------------SGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSP 1707
Query: 2354 ASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAM---DTPKPAVSDEKNINTFVETPVQK 2410
AST + V EE R S T P VS E +
Sbjct: 1708 ASTTS--------SGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDT 1759
Query: 2411 LDLLGNLPGSKRQPQTP-------KEKAEALEDLVGFKELFQ--TPGHTEESMTDDKITE 2461
G+ S P++ + L D L + TP H+ ++
Sbjct: 1760 TLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSP 1819
Query: 2462 VSCKSPQPES--FKTSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPT--G 2517
+ Q ES F++ SSK + P E S + +S TT T G
Sbjct: 1820 AGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLG 1879
Query: 2518 DSKSIKAFKESPKQIL---DPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEE 2574
S+ SP PA S T + T + + F E +A G +EE
Sbjct: 1880 RSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEE 1939
Query: 2575 SMTIDKNTKIPCKSPP---PELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTH 2631
S T +T SPP L + TS P + + + TSG+S
Sbjct: 1940 SRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDS-------STTSGRSEE 1992
Query: 2632 THKEPASGD-EGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSG 2690
+ +S D G VL R+ E S + + A P G T T G
Sbjct: 1993 STASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALP-----GST---TTPG 2044
Query: 2691 HTQESLTAGKATKIPCESPPLEVVDTTA------STKRHLRTRVQKVQVKEEPSAVKFTQ 2744
+++S T + + P + L TT+ ST H +R P +
Sbjct: 2045 LSEKSTTFHSSPRSPATT--LSPASTTSSGVSEESTTSH--SRPGSTHTTAFPDSTTTPG 2100
Query: 2745 TSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRPRAPRE-----SAQAI-- 2797
S +T + P D L ++ T P+ T S P + S A+
Sbjct: 2101 LSRHSTTSHSSPGSTD---TTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSF 2157
Query: 2798 --EDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEEL 2855
E P + HT ++ D TT + ++T S R T + L
Sbjct: 2158 GQESTTFHSSPGSTHT--TLFPDSTTSSGIVEASTRVHSSTGSPR--TTLSPASSTSPGL 2213
Query: 2856 LAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPL 2915
QT +THT P P+ E+ R P + P
Sbjct: 2214 QGESTAFQTHPASTHTTPSP------------PSTATAPVEESTTYHRSPGSTPTTHFPA 2261
Query: 2916 EDLASFQELSQTPGHTEELANG----AADSFTSAPKQTPDSG-KPLKISRRVLRAPKVEP 2970
S T H+ A+G +A S TS ++ S P L P
Sbjct: 2262 SSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTP 2321
Query: 2971 VGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDGSVTGTKRLRCMPAPEEIVEELPASKK 3030
ST +S + T P G G++ + + ++ P +
Sbjct: 2322 GLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSE 2381
Query: 3031 QRVAPRARGKSSEPVVIMKRSLRTSAKRIEP 3061
+ + S + R+ TS + EP
Sbjct: 2382 ESTTVYSSSPGSTETTVFPRTPTTSVRGEEP 2412
Score = 48.5 bits (114), Expect = 1e-04
Identities = 317/1608 (19%), Positives = 504/1608 (31%), Gaps = 226/1608 (14%)
Query: 1345 DLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPP----ESA---DTPTSTRRQPKTPLEK 1397
D T + + + + +TT P S+ P ES P ST P P
Sbjct: 1095 DSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTA 1154
Query: 1398 RDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKT 1457
+E + + S +T T P S ++ + T A+ T S H T
Sbjct: 1155 TAPVEESTTYHR----SPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTT 1210
Query: 1458 KEKAQPLEDLA--GLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSL 1515
+ + G E+ P T P E +T P T+ P S SL
Sbjct: 1211 SGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTF----YSSPRSPTTTLSPASMTSL 1266
Query: 1516 RKVDVEEEFFALRKR---TPSAGKAMHTPKPAVSGEKN-IYAFMGTPVQKLDLTENLTGS 1571
V EE R + T S T P +S E +Y+ + + T S
Sbjct: 1267 ---GVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTS 1323
Query: 1572 KRRLQ-TPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSK 1630
+ T A F E T G TEES ++ P +PAS++
Sbjct: 1324 VHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEES------------TAFPG---SPASTQ 1368
Query: 1631 RRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASL 1690
L +L + EE +S +T T P S +P ++ S+
Sbjct: 1369 TGLPATLTTADLGEESTTF----PSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTET 1424
Query: 1691 TGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHT------------KESMTNEKTTKVSYR 1738
T TP + E F ++P T +ES T+ ++
Sbjct: 1425 TTLPGSPTTPS----LSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHT 1480
Query: 1739 ASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDI--- 1795
+ PD T S+ + TE S G+ T + G+ +
Sbjct: 1481 TAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLP 1540
Query: 1796 -NTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQA--LEELTGFRELFQTPCTDNPTTDEK 1852
+T V+ + GS T A EE T F+ + + P+
Sbjct: 1541 DDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQS-WPSSSDTTPSPPGT 1599
Query: 1853 TTKKI-LCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTPKAAV 1911
T + + + S P+ TPT +L ++ EE + G A+ ++A
Sbjct: 1600 TAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRS---EESTTVHSSPGATGTALFPTRSAT 1656
Query: 1912 GEEKDINTFVGTPVEKLDLLGN-----LPGSKRRPQTPKEKAKALEDLAGFKELFQTPGH 1966
+ VG P G+ LPGS EK+ + +P
Sbjct: 1657 ------SVLVGEPTTSPISSGSTETTALPGSTTTAGL-SEKSTTFYSSPRSPDTTLSPAS 1709
Query: 1967 TEESMTDDKITEVSCKSPQPDPVKTPTSS-----KQRLKISLGKVGVKEEVLPVGKLTQT 2021
T S ++ T + P S+ Q S G + L G T +
Sbjct: 1710 TTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTAS 1769
Query: 2022 S--GKTTQTHRETAGDGKSIKAFKESAKQMLD---PANYGTGMERWPRTP------KEEA 2070
S ++T H ++ +A +L+ P + TG +P + E+
Sbjct: 1770 SLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGES 1829
Query: 2071 QSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLGKRDI 2130
+ + K+ P T + + TT S TPT+ T LG+
Sbjct: 1830 TTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPS------STPTTHFSASSTTLGRS-- 1881
Query: 2131 VEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKGKAQP 2190
EE + + T T P V TA P ++ T + T G+++
Sbjct: 1882 -EESTTVHSSPVATATTPSPARSTTSGLVEESTAYHS-SPGSTQTMHFPESSTASGRSEE 1939
Query: 2191 LEDL-AGLKELFQTPICT-----DKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSKRSLR 2244
+ +P T ++PT++ + + PD T + +S S
Sbjct: 1940 SRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDS-STTSGRSEESTASHS 1998
Query: 2245 KADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQ 2304
D + + T SV T P + A G+ PG S +
Sbjct: 1999 SQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTT----PGLSEKSTTFHS 2054
Query: 2305 TPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNL 2364
+P+ A L + + +++ TT + PD TP ++ +
Sbjct: 2055 SPRSPATTLSPAS----TTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHS 2110
Query: 2365 RKADVEEEFLALRKRT--PSAGKAMDTPKPAVSDEKNI--NTFVETPVQKLDLLGNLPGS 2420
+ L T PS P +D +T + Q+ + PGS
Sbjct: 2111 SPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGS 2170
Query: 2421 KRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSP----QPESFKTSR 2476
P + G E T H+ ++ S SP + +F+T
Sbjct: 2171 THTTLFPDSTTSS-----GIVEA-STRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHP 2224
Query: 2477 SSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTH----TEPTGDSKSIKAFKESPKQ- 2531
+S P E R+ G T TH + +G S+ F SP
Sbjct: 2225 ASTHTTPSPPSTATAPVEESTTYH--RSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDAS 2282
Query: 2532 --ILDPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSP 2589
A S T R + T + +PG TE T +P +
Sbjct: 2283 GTTPSSAHSTTSGRGESTTSR----------------ISPGSTEI-------TTLPGSTT 2319
Query: 2590 PPELTDTAT---STKRCPKTRPRKEVKEELSAVERLTQTSGQ--STHTHKEPAS------ 2638
P L++ +T S+ R P T L E T + Q STH+ PAS
Sbjct: 2320 TPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGL 2379
Query: 2639 GDEGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLE--------DLAGFTELSETSG 2690
+E V P E R P +P FTE S TSG
Sbjct: 2380 SEESTTVYSS----SPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSG 2435
Query: 2691 HTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETT 2750
T+ES T P + AST+ L + + EE + F +SG T
Sbjct: 2436 LTEES------TAFP---------GSPASTQTGLPATLTTADLGEE--STTFPSSSGSTG 2478
Query: 2751 DADKEPAGEDKGIKALKESAKQTPAPAASVT--GSRRRPRAPRESAQAIED-------LA 2801
G+ ++ +P+ + T GS P +S L+
Sbjct: 2479 TTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLS 2538
Query: 2802 GFKDPAAGHTEESMTDDK------TTKIP-CKSSPELEDTATSSKRRP 2842
++G +EES T TT P ++P L +T+S P
Sbjct: 2539 PATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSP 2586
Score = 48.1 bits (113), Expect = 1e-04
Identities = 279/1445 (19%), Positives = 462/1445 (31%), Gaps = 181/1445 (12%)
Query: 1345 DLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPP----ESA---DTPTSTRRQPKTPLEK 1397
D T + + + + +TT P S+ P ES P ST P P
Sbjct: 3735 DSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTA 3794
Query: 1398 RDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKT 1457
+E + + S +T T P S ++ + T A+ T S H T
Sbjct: 3795 TAPVEESTTYHR----SPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTT 3850
Query: 1458 KEKAQPLEDLA--GLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSL 1515
+ + G E+ P T P E +T P T+ P S SL
Sbjct: 3851 SGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTF----YSSPRSPTTTLSPASMTSL 3906
Query: 1516 RKVDVEEEFFALRKR---TPSAGKAMHTPKPAVSGEKN-IYAFMGTPVQKLDLTENLTGS 1571
V EE R + T S T P +S E +Y+ + + T S
Sbjct: 3907 ---GVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTS 3963
Query: 1572 KRRLQ-TPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSK 1630
RR + T A F E T G TEES ++ P +PAS++
Sbjct: 3964 VRREEPTTFHSRPASTHTTLFTEDSTTSGLTEES------------TAFPG---SPASTQ 4008
Query: 1631 RRLKTSLGKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASL 1690
L +L + EE +S +T T P S +P ++ S+
Sbjct: 4009 TGLPATLTTADLGEESTTF----PSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTET 4064
Query: 1691 TGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHT------------KESMTNEKTTKVSYR 1738
T TP + E F ++P T +ES T+ ++
Sbjct: 4065 TTLPGSPTTPS----LSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHT 4120
Query: 1739 ASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHTPKPAVGEEKDI--- 1795
+ PD T S+ + TE S G+ T + G+ +
Sbjct: 4121 TAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLP 4180
Query: 1796 -NTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRE---LFQT-PCTDNPTTD 1850
+T V+ + GS L T A + TG +E FQ+ P + + T
Sbjct: 4181 DDTITSGLVEASTPTHSSTGS---LHTTLTPASSTS--TGLQEESTTFQSWPSSSDTTPS 4235
Query: 1851 EKTTKKI---LCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPSAGKAMHTP 1907
+T + + + S P+ TPT +L ++ EE + G A+
Sbjct: 4236 PPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRS---EESTTVHSSPGATGTALFPT 4292
Query: 1908 KAAVGEEKDINTFVGTPVEKLDLLGN-----LPGSKRRPQTPKEKAKALEDLAGFKELFQ 1962
++A + VG P G+ LPGS EK+ +
Sbjct: 4293 RSAT------SVLVGEPTTSPISSGSTETTALPGSTTTAGL-SEKSTTFYSSPRSPDTTL 4345
Query: 1963 TPGHTEESMTDDKITEVSCKSPQPDPVKTPTSS-----KQRLKISLGKVGVKEEVLPVGK 2017
+P T S ++ T + P+S+ Q S G + L G
Sbjct: 4346 SPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGS 4405
Query: 2018 LTQTS--GKTTQTHRETAGDGKSIKAFKESAKQMLD---PANYGTGMERWPRTP------ 2066
T +S ++T H ++ +A +L+ P + TG +P
Sbjct: 4406 TTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTR 4465
Query: 2067 KEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPTSTRRRPKTPLG 2126
+ E+ + + K+ P T + + TT S TPT+ T LG
Sbjct: 4466 QGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPS------STPTTHFSASSTTLG 4519
Query: 2127 KRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASVTGSKRQPRTPKG 2186
+ EE + + T T P + E+ P ++ T + T G
Sbjct: 4520 RS---EESTTVHSSPVATATTPSPARSTTS-GLVEESTTYHSSPGSTQTMHFPESNTTSG 4575
Query: 2187 KAQP--LEDLAGLKELFQTPICT----DKPTTHEKTTKIACRSPQPDPVGTPTIFKPQSK 2240
+ + + + P T ++PT++ + + PD T + +S
Sbjct: 4576 RGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDS-STTSGRSEEST 4634
Query: 2241 RSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNLPGSK 2300
S D + + T SV T P + A G+ PG S
Sbjct: 4635 ASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTT----PGLSEKST 4690
Query: 2301 RWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRP 2360
+ +P F T ++E TT PV T +T P
Sbjct: 4691 TFHSSPSSTPTTH---------FSASSTTLGRSEESTTV------HSSPVAT--ATTPSP 4733
Query: 2361 KRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVSDEKN--INTFVETPVQKLDLLGNLP 2418
R+ VEE +P + + M P+ + + ++ T + + +
Sbjct: 4734 ARSTTSGLVEES--TAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTT 4791
Query: 2419 GSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSS 2478
+ + T + F E T G +EES + + +P P F TS
Sbjct: 4792 SALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRI 4851
Query: 2479 KQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPA-- 2536
+ + M+ T+ +T T + S + + SP Q L PA
Sbjct: 4852 AESTTFYISPGSME-----------TTLASTATTPGLSAKSTILYSSSRSPDQTLSPASM 4900
Query: 2537 --ASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTI-DKNTKIPCKSPPPEL 2593
+S++G L ++ E F + G ++ES T K P +
Sbjct: 4901 TSSSISGEPTSLYSQAESTHT----TAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSI 4956
Query: 2594 TDTATSTKRCPKTRPRKEVKEELSAVERLTQT----SGQSTHTHKEPASGDEGIKVLKQR 2649
T TS+ T P + LS V + T S +ST + P S +
Sbjct: 4957 T---TSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTE-----TTAF 5008
Query: 2650 AKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESP 2709
+ + + S P +P L T++ + S S A T +P S
Sbjct: 5009 SHSNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTDIGQESTAFHSSSDATGTTPLPARST 5068
Query: 2710 PLEVV 2714
++V
Sbjct: 5069 ASDLV 5073
Score = 47.8 bits (112), Expect = 2e-04
Identities = 346/1752 (19%), Positives = 535/1752 (30%), Gaps = 266/1752 (15%)
Query: 1356 PGHTEEAVAAGKTTKMPCESSPPESADTPTSTRR----QPKTPLEKRDVQKELSALKKLT 1411
PG T A + K+T P+ +P T + T R A T
Sbjct: 268 PGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDST 327
Query: 1412 QTSG---ETTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLA 1468
G E+T + +PG D +++ T + + S + KT + +
Sbjct: 328 TMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTT-RLPDNTTTS 386
Query: 1469 GLKELFQTPV--CTDKP-TTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFF 1525
GL E TPV T P TT ++ +P + SSK S +
Sbjct: 387 GLLEA-STPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLS 445
Query: 1526 ALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTPK--EKAQ 1583
+PS+ H + S ++ TPV + T R T E++
Sbjct: 446 TTYHSSPSSTPTTHF---SASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEEST 502
Query: 1584 ALEDLAG------FKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSL 1637
A G F E T GH+EES T + KSS P A + +SL
Sbjct: 503 AYHRSPGSTQTMHFPESSTTSGHSEESATFHGST-THTKSS--TPSTTAALAHTSYHSSL 559
Query: 1638 GKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKS--MKAFMESPKQILDSAASLTGSKR 1695
G S ETTH T G+S KA SP + + +
Sbjct: 560 G-----------------STETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPS 602
Query: 1696 QLRTPKGKSEVPEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQPDLVDTPTSSKPQP 1755
L G S +G +E P T + +EK+T PD P
Sbjct: 603 VL---VGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPA------ 653
Query: 1756 KRSLRKADTEEEFLAFRKQ---TPSAGKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNL 1812
S+ + EE + T + T P + +E + P PG+
Sbjct: 654 --SMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGST 711
Query: 1813 ---------------PGS--------NRRLQTRKEKAQALEELTGFRELFQTPCTDNPTT 1849
PGS N E + + T +P
Sbjct: 712 TASSLGPEYTTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQ 771
Query: 1850 DEKTTKKILCKSPQSDPAD--------TPTNTKQRPKRSLKKADVE---------EEFLA 1892
E TT S + PA P+ T S+ + EE
Sbjct: 772 GESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTT 831
Query: 1893 FRKLTPSAGKAMHTPKA--AVGEEKDINTFVGTPVEKLDLLGNLPGSKRRPQTPKEKAKA 1950
+ +P + + MH P++ G ++ T + + + + T +
Sbjct: 832 YHS-SPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPG 890
Query: 1951 LEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLGKVGVKE 2010
F + T G +EES + + P T + + ++
Sbjct: 891 STATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMET 950
Query: 2011 EVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQ---MLDPAN-YGTGMERWPRTP 2066
LP G TT T G + F S + L PA+ +G+ T
Sbjct: 951 TALP--------GSTT-----TPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTS 997
Query: 2067 KEEAQSLEDLAGFKELFQTPDHTEESTTD-------DKTTKIACKSPPPESMDTPTSTRR 2119
+ S A F + TP + STT D T A + S ++ TS
Sbjct: 998 RSRPGSTHTTA-FPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSS 1056
Query: 2120 RPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRETAKQKLDPAASV---TG 2176
T + Q + T H++ PG + T+ ++ + V TG
Sbjct: 1057 SGSTDTALSPGSTTALSFGQESTTFHSN--PGSTHTTLFPDSTTSSGIVEASTRVHSSTG 1114
Query: 2177 SKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVGTPTIFK 2236
S R +P P L G FQ T +TH TT P P T T
Sbjct: 1115 SPRTTLSPASSTSP--GLQGESTAFQ----THPASTH--TT--------PSPPSTAT--- 1155
Query: 2237 PQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTPVQKLDLPGNL 2296
A VEE + R + G + F +P D G
Sbjct: 1156 ---------APVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSP----DASGTT 1202
Query: 2297 PGSKRWPQTPKEKAQALEDLAGFKELFQTPG-TDKPTTDEKTTKIACKSPQPDPVDTPAS 2355
P S + + ++ G E+ PG T P E +T P +PAS
Sbjct: 1203 PSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPAS 1262
Query: 2356 TKQRPKRNLRKADVEEEFLALRKR---TPSAGKAMDTPKPAVSDE-----KNINTFVETP 2407
+ V EE R + T S T P +S+E + ET
Sbjct: 1263 --------MTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETT 1314
Query: 2408 VQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSP 2467
V ++ G +P T + + + F E T G TEES T + S ++
Sbjct: 1315 VFPHSTTTSVHG--EEPTTFHSRPASTHTTL-FTEDSTTSGLTEES-TAFPGSPASTQTG 1370
Query: 2468 QPESFKTSRSSKQRLKIPLV--KVDMKEEPL-----------AVSKLTRTSGETTQTHTE 2514
P + T+ ++ P K P S+L+ +S ETT
Sbjct: 1371 LPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGS 1430
Query: 2515 PTGDSKSIKA-----FKESPKQILDPAASVT------GSRRQLRTRKEKARALEDLVDFK 2563
PT S S K+ SP L PA + + S + A D
Sbjct: 1431 PTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTS 1490
Query: 2564 ELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCP-----KTRPRKEVKEELSA 2618
+L P + S + T P + L +T+ P P + L
Sbjct: 1491 DLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVE 1550
Query: 2619 VERLTQTSGQSTHTHKEPASG-DEGIKVLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLE 2677
T +S S HT PAS G++ + P+ + PS P A P+E
Sbjct: 1551 ASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPS-----PPGTTAAPVE 1605
Query: 2678 ------------DLAGFTELSETSGHTQESLT--------------AGKATKIPCESPPL 2711
F+ S T G ++ES T AT + P
Sbjct: 1606 VSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTT 1665
Query: 2712 EVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAK 2771
+ + ++ L + E+ + + S +TT + ++ ++
Sbjct: 1666 SPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSR 1725
Query: 2772 QTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPEL 2831
+ GS P +ES A P G T+ +++ TT PE
Sbjct: 1726 PGSTHTTAFPGSTTMPGVSQEST------ASHSSP--GSTDTTLSPGSTT--ASSLGPES 1775
Query: 2832 EDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVG----EGKGTKAFKQ 2887
+S T LL +S + HT P G +G+ T
Sbjct: 1776 TTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSW 1835
Query: 2888 P-AKRKLDAEDVIGSRRQPRAPKEKAQPLE-DLASFQELSQTPGHTEEL----ANGAADS 2941
P +K + A S + P F S T G +EE ++ A +
Sbjct: 1836 PSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATA 1895
Query: 2942 FTSAPKQTPDSG 2953
T +P ++ SG
Sbjct: 1896 TTPSPARSTTSG 1907
Score = 34.7 bits (78), Expect = 1.6
Identities = 112/539 (20%), Positives = 181/539 (33%), Gaps = 73/539 (13%)
Query: 2499 SKLTRTSGETTQT--HTEPTGDSKSIKAFKESPK---QILDPAASVTGSRRQLRTRKEKA 2553
S +T S ETT T G S+ F SP+ + L PA + + + T
Sbjct: 255 SPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSR 314
Query: 2554 RALEDLVDFKELFSAPGHTEES-----------MTIDKNTKIPCKSPPPELTDTATSTKR 2602
+ F + + PG ++ES T+ T P S PE T +S
Sbjct: 315 PGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTP-SSLGPESTTFHSSPGY 373
Query: 2603 CPKTR-PRKEVKEELSAVERLTQTSGQSTHTHKEPASG--DEGIKVLKQ----RAKKKPN 2655
TR P L +S S HT P+S EG Q P
Sbjct: 374 TKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPA 433
Query: 2656 PVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVD 2715
P + + + F+ S T GH++ES + +PP
Sbjct: 434 PSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSPVATATTPP----P 489
Query: 2716 TTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPA 2775
++T H+ + + F ++S TT E + G + + TP+
Sbjct: 490 ARSATSGHVEESTAYHRSPGSTQTMHFPESS--TTSGHSEESATFHG--STTHTKSSTPS 545
Query: 2776 PAASVTGSRRRPRAPRESAQAIEDLAGFKDPA--AGHTEESMTDDK------TTKIPCKS 2827
A++ S+ + F+D + +G +EES TT +P S
Sbjct: 546 TTAALA------HTSYHSSLGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGS 599
Query: 2828 SPE--LEDTATS--SKRRPRTRAQKVEVKEELLAVGKLT----QTSGETTHTDKEPVGEG 2879
+P + D+ S S T A + L+ T S +TTH G
Sbjct: 600 TPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSG 659
Query: 2880 ---KGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTE-ELA 2935
+ T + +P A GS P +E +PG T+ L+
Sbjct: 660 VSEESTTSHSRPGSTHTTA--FPGSTTMPGLSQESTAS----------HSSPGPTDTTLS 707
Query: 2936 NGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKS-NTSLPP 2993
G+ + + P+ T +P +L P ++ PV S ++S +T+L P
Sbjct: 708 PGSTTASSLGPEYTTFHSRPGSTETTLL--PDNTTASGLLEASMPVHSSTRSPHTTLSP 764
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 60.1 bits (144), Expect = 4e-08
Identities = 291/1487 (19%), Positives = 507/1487 (34%), Gaps = 212/1487 (14%)
Query: 1789 VGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCTDNPT 1848
V E+ FL PV LD + ++ RK KA+ L + P + + +
Sbjct: 30 VKEQSGQKCFLAQPVTLLDIYTHWQQTSEL--GRKRKAEEDAALQAKKTRVSDPISTSES 87
Query: 1849 TDE---------KTTKKILCKSPQSDPADTPTNTKQRPKRSLKKADVEEEFLAFRKLTPS 1899
++E K T ++ + AD P++ K++ K +KA + P+
Sbjct: 88 SEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPH----PA 143
Query: 1900 AGKAMHTPKAAVGEEKDINTFVGTP-VEKLDLLGNLP--GSKRRPQTPKEKAKALEDLAG 1956
GK + + K T V + + G++P G+ +P G
Sbjct: 144 TGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKP--------------G 189
Query: 1957 FKELFQTPGHTEESMTDDKITEVSCK-SPQPDPVK-----TPTSSKQRLKISLGKVG--- 2007
Q +E++ + T+V K S +P VK T S ++ + GKVG
Sbjct: 190 MVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVT 249
Query: 2008 --VKEEVLPVGKLTQTSGKTTQTHRE--------TAGDGKSIKAFKE--SAKQMLDPANY 2055
VK LP K + + +++ E AG +KA ++ + PA
Sbjct: 250 PQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKG 309
Query: 2056 GTGMERWPRTP-KEEAQSLEDLAGFKELFQTPDHTEESTTDDKT--------TKIACKSP 2106
G P P K A + + AG E E S ++++T K + K+
Sbjct: 310 TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTS 369
Query: 2107 PPESMDTPTSTRRR----PKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVFRE 2162
+ P R P P V + A K+ + + + E++ +
Sbjct: 370 QVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKP 429
Query: 2163 TAKQKLDPAASVTGSKRQPR-----TPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTT 2217
+ K AAS +K PR P K P + + + + + + ++
Sbjct: 430 SGKAPQVRAASAP-AKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREA 488
Query: 2218 KIACRSPQPDPVGTPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEK 2277
A + Q P+G KP S + + K P+ A G E+
Sbjct: 489 LAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQ-----VGKWEE 543
Query: 2278 DMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTD--E 2335
D ++ D + P A A E G + Q T P +
Sbjct: 544 DSESSSEESSDSSD-----------GEVPTAVAPAQEKSLG--NILQAKPTSSPAKGPPQ 590
Query: 2336 KTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKPAVS 2395
K +A + P+D S+++ AD EE A+ A A+ P+
Sbjct: 591 KAGPVAVQVKAEKPMDNSESSEESSD----SADSEEAPAAMT--AAQAKPALKIPQTKAC 644
Query: 2396 DEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMT 2455
+K NT V + + P +P + A+ G + + +EES +
Sbjct: 645 PKKT-NTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAG--GTQRPAEDSSSSEESDS 701
Query: 2456 DDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKE---EPLAVSKLTRTSGETTQTH 2512
+++ T ++ Q ++S + L++ V +K + A +T TQ
Sbjct: 702 EEEKTGLAVTVGQ------AKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVK 755
Query: 2513 TEPTGDSKSIKAFKESPKQILDPAASVTGSRR-QLRTRKEKARALEDLVDFKELFSAPGH 2571
E DS+S + +S + PA T ++ Q + ARA K SAPG
Sbjct: 756 AEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARA----PSAKGTISAPGK 811
Query: 2572 TEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTH 2631
+ K PP +T R P + P K +A + T S
Sbjct: 812 VVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVG-KAVATAAQAQTGPEEDSGS 870
Query: 2632 THKEPASGDEGIKVLKQRAKKKPN-------PVEEEPSRRRPRAPKEKAQPL-------E 2677
+ +E S +E + + + K + P +E P + P K P +
Sbjct: 871 SEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQD 930
Query: 2678 DLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRVQKVQVKEEP 2737
D +E S++ G ++T+ + K PPL VD S T Q Q P
Sbjct: 931 DSGSSSEESDSDGEAPAAVTSAQVIK-----PPLIFVDPNRSPAGPAATPAQ-AQAASTP 984
Query: 2738 SAVKFTQT-----SGETTDADKEPAGE--DKGIKA---LKESAKQTPAPAASVTGSRRRP 2787
+ +++ S E+ D D PA + GI+ +A AP AS+ G+
Sbjct: 985 RKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSK 1044
Query: 2788 RAPRES--------AQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPEL-------- 2831
+ R S A ++ G PA S+ T K+ PE+
Sbjct: 1045 ESSRISDGKKQEGPATQVDSAVGTL-PATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPE 1103
Query: 2832 -----EDTATSSKRRPRTRAQKVEVKEELLAVGK--------LTQTSGETTHTDKEPVGE 2878
ED++ SS K VG + +T+ E++ D +
Sbjct: 1104 SSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQ 1163
Query: 2879 G--KG------TKAFKQPAKR--KLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTP 2928
G T A Q +K KLD+ + S + + Q + + LS
Sbjct: 1164 SLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKT 1223
Query: 2929 GHTEELANGAADSFTSAPKQTPDS-----------------GKPLKISRRVLRAPKVEPV 2971
G +E A+G + PK+ + G+P ++ ++A V+ +
Sbjct: 1224 GG-KEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVL 1282
Query: 2972 GDVVST-RDPVKSQSKSNTSLPPLPFKRGGGKDGSVTGT---KRLRCMPAPE----EIVE 3023
+++ R V +K ++ KR D T K+ + + A E +
Sbjct: 1283 TELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSP 1342
Query: 3024 ELPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSV 3083
E ++ + A R + K SL + + EP EEL + S
Sbjct: 1343 EKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSK 1402
Query: 3084 PENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKKPMKTSPE 3130
E K R + + K E +++ + + +KK KT+ +
Sbjct: 1403 KEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQ 1449
Score = 52.0 bits (123), Expect = 1e-05
Identities = 129/674 (19%), Positives = 239/674 (35%), Gaps = 126/674 (18%)
Query: 2590 PPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQR 2649
P L D T ++ + +++ +E+ + + T+ S + + S +E + +
Sbjct: 43 PVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSE----SSEEEEEAEAET 98
Query: 2650 AKKKPNPVEEEPS---RRRPRAPKEKAQPLEDLAGFTELS---ETSGHTQESLTAGKATK 2703
AK P S P + KEKA+ + AG T S +G T +L +GK+ +
Sbjct: 99 AKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPR 158
Query: 2704 IPCESPPLEVVDTTASTKRH-------LRTRVQKVQVKEEPSAVKFTQTSGETTDADKEP 2756
E P + T+ + V + S+ + T +S + TD + +P
Sbjct: 159 KSAE--PSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKP 216
Query: 2757 AGEDKGIKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMT 2816
+ + +KA S K++PA R+ AP + + G P A
Sbjct: 217 SVKPAQVKASSVSTKESPA--------RKAAPAPGKVGDVTPQVKGGALPPA-------- 260
Query: 2817 DDKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPV 2876
K K P + S E+ + S + P +V+ E++L V + + T P
Sbjct: 261 --KRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPA 318
Query: 2877 GEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELAN 2936
GK + S+ + P+E ++
Sbjct: 319 PPGKA---------------GAVASQTKAGKPEEDSE----------------------- 340
Query: 2937 GAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPF 2996
S+ +++ DS + ++ +L+A V + P K +S + P P
Sbjct: 341 -------SSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAK-ESPRKGAAPAPPG 392
Query: 2997 KRGGGKDGSVTGTKRLRCMPAPEE--IVEELPA-SKKQRVAPRARGKSSEPVVIMKRSLR 3053
K G + G + + EE EE PA +K AP+ R S+ K S R
Sbjct: 393 KTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAP----AKESPR 448
Query: 3054 TSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAE 3113
A P KT ++Q + +++ +E+ ++ LA
Sbjct: 449 KGAAPAPP--------RKTGPAAAQVQVG---------KQEEDSRSSSEESDSDREALA- 490
Query: 3114 RIEINRNEKKPMKTSPEMDI-----QNPDDGARKPIPRDKV---TENKRCLRSARQNESS 3165
+N + KP+ SP++ P P+P KV T + + + +ESS
Sbjct: 491 --AMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESS 548
Query: 3166 QPKVAEESGGQKSAKVLMQNQKGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVTRS 3225
+ ++ S G+ V +K G + K S PA + V
Sbjct: 549 SEESSDSSDGEVPTAVAPAQEKSLGN--------ILQAKPTSSPAKGPPQKAGPVAVQVK 600
Query: 3226 VKRCAENPKKAEDN 3239
++ +N + +E++
Sbjct: 601 AEKPMDNSESSEES 614
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 59.3 bits (142), Expect = 6e-08
Identities = 164/847 (19%), Positives = 297/847 (35%), Gaps = 104/847 (12%)
Query: 2420 SKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSK 2479
S R P TPK+K K+ + G ES + + + S K + S S+ K
Sbjct: 179 SSRSP-TPKQKK---------KKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRK 228
Query: 2480 QRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASV 2539
R P K K++ S+ T + ++ + H + DS S S +
Sbjct: 229 HRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHT 288
Query: 2540 TGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATS 2599
T + + R D FS PG T P +TAT
Sbjct: 289 TALAGRSPSPASGRRGEGDAP-----FSEPGTTSTQR--------------PSSPETATK 329
Query: 2600 TKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEE 2659
P K+ KE+ + S + + T EP + +L +R P P+
Sbjct: 330 QPSSPYEDKDKDKKEKSAT---RPSPSPERSSTGPEPPAPTP---LLAERHGGSPQPLAT 383
Query: 2660 EPSRRRPRAPKEKAQPLEDLAG--FTELSETSGHTQESLTAGKATKI------------- 2704
P + P P +A P D + E S ++ S + + TK+
Sbjct: 384 TPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKP 443
Query: 2705 -PCESPPLEVVDTTASTKR-HLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKG 2762
P E+ + S R H R + K + T + PA +G
Sbjct: 444 APAPGSHREISSSPTSKNRSHGRAKRDK----------SHSHTPSRRMGRSRSPATAKRG 493
Query: 2763 IKALKESAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKT-- 2820
+ K+ + + S R R +++ + + P S +
Sbjct: 494 RSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGR 553
Query: 2821 TKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGK 2880
++ + AT + R RT A++ + A + +++ T + +
Sbjct: 554 SRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPA-RRRSRSRTPTRRRSRSRTPARR 612
Query: 2881 GTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAAD 2940
G + PA+R+ + R + R+P + S + S+TP G +
Sbjct: 613 GRSRSRTPARRRSRTRSPVRRRSRSRSPARR--------SGRSRSRTPAR-----RGRSR 659
Query: 2941 SFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVS-TRDPVKSQSKSNT------SLPP 2993
S T A + S P +RR R+ P S +R P + +S+S + S
Sbjct: 660 SRTPARRGRSRSRTP---ARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSR 716
Query: 2994 LPFKRGGG------KDGSVTGTKRLRCMPAPEEIVEELPASKKQRVA-PRARGKSSEPVV 3046
P +RG K+ S T +R R +PE + + + + ++ PR++ KS +
Sbjct: 717 TPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR---L 773
Query: 3047 IMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRS---RRQNKTEAEQ 3103
++RSL S+ + + ++ + K + P + S S ++++KT + Q
Sbjct: 774 SLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQ 833
Query: 3104 QITEVFVLAERIEINRNEKKPMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQNE 3163
+ +++ ++ TSP+ + Q+ R E K S
Sbjct: 834 SHSSSSP-HPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCS 892
Query: 3164 SSQPKVAEESGGQKSAKVLMQNQKGKGEAGNSDSMCLRSRKTKSQPAASTLESKSVQRVT 3223
S P + S + + + + K +A S RS S P+ S + S++ R +
Sbjct: 893 GSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQ--RSHSGSSSPSPSRVTSRTTPRRS 950
Query: 3224 RSVKRCA 3230
RSV C+
Sbjct: 951 RSVSPCS 957
Score = 54.3 bits (129), Expect = 2e-06
Identities = 148/773 (19%), Positives = 266/773 (34%), Gaps = 98/773 (12%)
Query: 2310 AQALEDLAG--FKELFQTPGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKA 2367
++ EDL G +L P D +++ + PD V+ + +
Sbjct: 1349 SEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQ-------- 1400
Query: 2368 DVEEEFLALRKRTPSAGKAMDTPKPAVSD--------------EKNINTFVETPVQKLDL 2413
+ L RTPS ++ P + D + TP + L
Sbjct: 1401 SISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTP-SRHSL 1459
Query: 2414 LGNLPGSKRQPQTPKEKAEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFK 2473
G+ PG K P+TP + K L QTP S + ++ C +PQ E
Sbjct: 1460 SGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNN-KCLTPQRERSG 1518
Query: 2474 TSRSSKQRLKIPLVKVDMKEEPLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQIL 2533
+ S Q+ + PL SG + + +P+ + SP
Sbjct: 1519 SESSVDQKT--------VARTPLGQRS---RSGSSQELDVKPSASPQERSESDSSPD--- 1564
Query: 2534 DPAASVTGSRRQLRTRKEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPEL 2593
S +R LR R + E VD K S P + + + K
Sbjct: 1565 ----SKAKTRTPLRQRSRSGSSPE--VDSKSRLS-PRRSRSGSSPEVKDKPRAAPRAQSG 1617
Query: 2594 TDTATSTKR-CPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKK 2652
+D++ K P+ PR+ S + ST + E K R
Sbjct: 1618 SDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPP-----KSRTARRGS 1672
Query: 2653 KPNPVEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLE 2712
+ +P + SR PR ++ P EL+ + ++ S +A + + +PP
Sbjct: 1673 RSSPEPKTKSRTPPRRRSSRSSP--------ELTRKARLSRRSRSASSSPETRSRTPPRH 1724
Query: 2713 VVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKG-IKALKESAK 2771
+ S+ + + + + S+ + TS +P G + ++ +E +
Sbjct: 1725 RRSPSVSSPEPAE-KSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTR 1783
Query: 2772 QT---PAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSS 2828
T +S + SRRR R+ S G +G+ S ++++ +
Sbjct: 1784 TTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGG-----SGYHSRSPARQESSRTSSRRR 1838
Query: 2829 PELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQP 2888
T +S++R R+R K T + + P+ + +++ P
Sbjct: 1839 RGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRS----RTPLISRRRSRSRTSP 1894
Query: 2889 AKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPK- 2947
R+ +RR+ R+ +A P+ S S+TP T + + +
Sbjct: 1895 VSRRRSRSRTSVTRRRSRS---RASPVSRRRS---RSRTPPVTRRRSRSRTPTTRRRSRS 1948
Query: 2948 QTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDGSVT 3007
+TP P+ R R P V T + +S+S TS P+ +R + VT
Sbjct: 1949 RTP----PVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTS--PVTRRRSRSRTSPVT 2002
Query: 3008 GTKRLRCMPAP---EEIVEELPASKKQR------VAPRARGKSSEPVVIMKRS 3051
+R R +P P + ++R + PR R +S P+ I +RS
Sbjct: 2003 -RRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRS 2054
Score = 52.8 bits (125), Expect = 6e-06
Identities = 298/1627 (18%), Positives = 544/1627 (33%), Gaps = 244/1627 (14%)
Query: 1500 PVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPV 1559
PV + S+ ++RS R R RTP+ + PA G TP
Sbjct: 630 PVRRRSRSRSPARRSGRS----------RSRTPARRGRSRSRTPARRGRSR----SRTPA 675
Query: 1560 QKLDLTENLTGSKR---RLQTPKEKAQALEDLA----GFKELFQTRGHTEESMTNDKTAK 1612
++ + + T ++R R +TP+ L Q RG + S ++
Sbjct: 676 RRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSR 735
Query: 1613 VACK----SSQPDPDKNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSG---ETTHTHTE 1665
+ + +S P+ K+ SS+R S + K L L+ +S + + T
Sbjct: 736 TSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPR 795
Query: 1666 PTGDGKSM-KAFMESPKQILDSAASLTGSKRQLRTPKGKSEVPEDLAGFIELFQTPSHTK 1724
+ G S KA +P + S++S K++ +TP +S ++ P +
Sbjct: 796 RSRSGSSQPKAKSRTPPRRSRSSSS-PPPKQKSKTPSRQSHSSSSPHPKVKSGTPPR--Q 852
Query: 1725 ESMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEEEFLAFRKQTPSAGKAMHT 1784
S+T+ + + S + + S P P+ R + + S+ +
Sbjct: 853 GSITSPQANEQSVTPQRRSCFE----SSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQS 908
Query: 1785 PKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELTGFRELFQTPCT 1844
P + + + + +P Q+ + P +R T R +PC+
Sbjct: 909 PSRSSSPQPKVKAII-SPRQRSHSGSSSPSPSR----------VTSRTTPRRSRSVSPCS 957
Query: 1845 DNPTTDEKTTKKILCKSPQSDPADTPTNTK-QRPKRSLKKADVEEEFLAFRKLTPSAGKA 1903
+ ++L + S + T K + P R + + + TP G +
Sbjct: 958 N-------VESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISP-YPKVKAQTPP-GPS 1008
Query: 1904 MHTPKAAVGEEKDINTFVGTPVEKLDLLGNLPGS---------------KRRPQTPKEKA 1948
+ K+ +EK ++ V + L L + S K + QT +
Sbjct: 1009 LSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHR 1068
Query: 1949 KALEDLAGFKELFQTPGHTEESMTDDKITEVSCKSPQPDPVKTPTSSKQRLKISLGKVGV 2008
+ ++P +S T K SP + + R + S + +
Sbjct: 1069 SDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPM-L 1127
Query: 2009 KEEVLPVGKLTQTSGKTTQTHRETAGDGKSIKAFKESAKQMLDP----ANYGTGMERWPR 2064
K + P Q+ + T + G+S ES ++M P A ++
Sbjct: 1128 KSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKF 1187
Query: 2065 TPKEEAQSLEDLAGFKELFQTPDHTEESTTDDKTTKIACKSPPPESMDTPT-STRRRPKT 2123
+P E FK+ +TP TK + P S D + +
Sbjct: 1188 SPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEE 1247
Query: 2124 PLGKRDIVEELSALKQLTQTTHTDKVPGDEDK---GINVFRETAKQKLDP------AASV 2174
P G+ I+ LS+ + T++ + P E++ + + + ++ L+ A+S
Sbjct: 1248 PAGQ--ILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSW 1305
Query: 2175 TGSKRQPRTPKGKAQPL-EDLAGLKELFQT--PICTDKPTTHEKTTKIACRSPQPDPVGT 2231
G P + PL E+ G F+ P+ T+ T K P + + T
Sbjct: 1306 GGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLET 1365
Query: 2232 -PTI-FKPQSKRSLRKADVEEESLALRK------------------RTPSVGKAMDTPKP 2271
P++ K QS RS + E A+ K RTPS ++ P
Sbjct: 1366 DPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSP 1425
Query: 2272 A--------------GGDEKDMKAFMGTPVQKLDLPGNLPGSKRWPQTPKEKAQALEDLA 2317
G ++ GTP + L G+ PG K P+TP +
Sbjct: 1426 EMKDGLPRTPSRRSRSGSSPGLRDGSGTP-SRHSLSGSSPGMKDIPRTPSRGRSECDSSP 1484
Query: 2318 GFKELFQT--PGTDKPTTDEKTTKIACKSPQPDPVDTPASTKQRPKRNLRKADVEEEFLA 2375
K L QT P + P++ E K C +PQ + + +S Q+ V L
Sbjct: 1485 EPKALPQTPRPRSRSPSSPELNNK--CLTPQRERSGSESSVDQK--------TVARTPLG 1534
Query: 2376 LRKRTPSAGKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQPQTPKEKAEALE 2435
R R+ S+ + +D KP+ S ++ + + P SK + +TP +
Sbjct: 1535 QRSRSGSS-QELDV-KPSASPQERSES------------DSSPDSKAKTRTPLRQRSRSG 1580
Query: 2436 DLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEEP 2495
+ S + ++ + +P+ +S S K P P
Sbjct: 1581 SSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQS---GSDSSPEPKAP--------AP 1629
Query: 2496 LAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRKEKARA 2555
A+ + +R+ + P G S + + + PK RT + +R
Sbjct: 1630 RALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKS---------------RTARRGSR- 1673
Query: 2556 LEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKR------CPKTRPR 2609
S+P +S T + PELT A ++R P+TR R
Sbjct: 1674 -----------SSPEPKTKSRTPPRRRS---SRSSPELTRKARLSRRSRSASSSPETRSR 1719
Query: 2610 KEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKK-KPNPVEEEPSRRRPRA 2668
+ S + + +S + + ++ K +R + P P + SR R R
Sbjct: 1720 TPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRR 1779
Query: 2669 PKEKAQPLEDLAGFTELSETSGHTQESLTAGKATK-------IPCESPPLEVVDTTASTK 2721
K + D +G ++ TS Q S + + T+ SP + T+S +
Sbjct: 1780 EKTRTTRRRDRSGSSQ--STSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRR 1837
Query: 2722 RHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVT 2781
R R+R K S T+ A + + + S +TP + +
Sbjct: 1838 RRGRSRTPPTSRKRSRS---------RTSPAPWKRSRSRASPATHRRSRSRTPLISRRRS 1888
Query: 2782 GSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRR 2841
SR P + R S A + +T + + S +++RR
Sbjct: 1889 RSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRS---RSRTPTTRRR 1945
Query: 2842 PRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGS 2901
R+R V + +T+ + + P+ + +++ P R+ S
Sbjct: 1946 SRSRTPPVTRRRSRSRTPPVTR---RRSRSRTSPITR-RRSRSRTSPVTRRRSR-----S 1996
Query: 2902 RRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKPLKISRR 2961
R P + + + S+TP + + P++ S PL I RR
Sbjct: 1997 RTSPVTRRRSRSRTSPVTRRRSRSRTP---PAIRRRSRSRTPLLPRKRSRSRSPLAIRRR 2053
Query: 2962 VLRAPKVEPVGDVVSTRDPV---------KSQSKSNTSLPPLPFKRGGGKDGSVT-GTKR 3011
G TR P S +S ++ PP G + V + R
Sbjct: 2054 SRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSR 2113
Query: 3012 LRCMPAP 3018
+ C P
Sbjct: 2114 MSCFSRP 2120
Score = 51.6 bits (122), Expect = 1e-05
Identities = 154/773 (19%), Positives = 271/773 (35%), Gaps = 141/773 (18%)
Query: 2547 RTRKEKARALEDLVDFKELFSAPGHTEES----------MTIDKNTKIPCKSPPPELTDT 2596
R R+ + R LE +E+ G+ E+ M ++K+ K P
Sbjct: 62 RKRRVELRCLE----LEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPA 117
Query: 2597 ATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGD--EGIKVLKQRAKKKP 2654
T T + + +K ERL G S ++ + +S D + KQ A + P
Sbjct: 118 VTETHQLAELNEKKN--------ERLRAAFGISD-SYVDGSSFDPQRRAREAKQPAPEPP 168
Query: 2655 NP---VEEEPSRRRPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPL 2711
P V E S R P ++K + +D SE+S +E + K K ES
Sbjct: 169 KPYSLVRESSSSRSPTPKQKKKKKKKDRG---RRSESSSPRRERKKSSKKKKHRSESESK 225
Query: 2712 EVVDTTASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAK 2771
+ + + K +++ +K + + ++ + +T AD + + ++ +AK
Sbjct: 226 KRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAK 285
Query: 2772 QTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPEL 2831
++ G P + R E A F +P T+ + + TK P SSP
Sbjct: 286 ---THTTALAGRSPSPASGRRG----EGDAPFSEPGTTSTQRPSSPETATKQP--SSP-Y 335
Query: 2832 EDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKR 2891
ED K + TR S E + T EP PA
Sbjct: 336 EDKDKDKKEKSATR----------------PSPSPERSSTGPEP------------PAPT 367
Query: 2892 KLDAEDVIGS---------RRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSF 2942
L AE GS ++P P +A P D P E+L
Sbjct: 368 PLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRD-------RSPPKSPEKLPQ------ 414
Query: 2943 TSAPKQTPDSGKPLKISRRVL---RAPKVEP-------VGDVVSTRDPVKSQSKSNTSLP 2992
+S+ + +P S +P K+SR +PK P + ++++ ++K + S
Sbjct: 415 SSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHS 474
Query: 2993 PLPFKRGG----------GKDGSVTGTKRLRCMPAPEEIVEELPASKKQRV-APRARGKS 3041
P +R G G+ S T TKR + A + R +P+ RG+S
Sbjct: 475 HTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRS 534
Query: 3042 SEPV-VIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGIS---------- 3090
P RS T + + + ++ + + P +G S
Sbjct: 535 RSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRS 594
Query: 3091 -----LRSRRQNKTEAEQQITEVFVLAERIEINRNEKKPMKTSPEMDIQNPDDGARKPIP 3145
R R +++T A + + A R R+ + S ++ +R P
Sbjct: 595 RSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPAR 654
Query: 3146 RDKVTENKRCLRSARQNESSQPKVAEESGGQKS----AKVLMQNQKGKGEAGNSDSMCLR 3201
R + R AR+ S A SG +S + +++ + S S+ R
Sbjct: 655 RGR----SRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRR 710
Query: 3202 SRKTKSQP-----AASTLESKSVQRVTRSVKRCAENPKKAEDNVCVKKIRTRS 3249
R P + S+ E K+ R ++ R +P+ + + ++ R+ S
Sbjct: 711 GRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLS 763
Score = 49.7 bits (117), Expect = 5e-05
Identities = 344/1862 (18%), Positives = 619/1862 (33%), Gaps = 257/1862 (13%)
Query: 92 DRSFRYENESLQNGRKSTEFPRKIREQEPARRVSRSSFSSDPDEKAQDSKAYSKITEGKV 151
DR R E+ S + RK + +K R + +++ S + K++D K +
Sbjct: 195 DRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPA 254
Query: 152 SGNPQVHIKNVKED-STADDSKDSVAQGTTNVHSSEHAGRNGRNAADPISGDFKEISSVK 210
+ + H + S++D S+ H++ AGR+ P SG E +
Sbjct: 255 PKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRS----PSPASGRRGEGDAP- 309
Query: 211 LVSRYGELKSVPTTQCLDNSKKNESPFWKLYESVKKELDVKSQKENVLQYCRKSGLQTDY 270
S G + + +K+ SP+ E K +KE KS +
Sbjct: 310 -FSEPGTTSTQRPSSPETATKQPSSPY---------EDKDKDKKE-------KSATRPSP 352
Query: 271 ATEKESADGLQ-GETQLLVSRKSRPKSGGSGHAVA------EPASPEQELDQNKGKGRDV 323
+ E+ S T LL R GGS +A EP +P E + +
Sbjct: 353 SPERSSTGPEPPAPTPLLAERH-----GGSPQPLATTPLSQEPVNPPSEASPTRDRSPPK 407
Query: 324 ESVQTP-SKAVGASFPLYEPAKMKTPVQYSQQQNSPQKHKNKDLYTTGRRESVNLGKSEG 382
+ P S + +S P +P K+ S + P + S N
Sbjct: 408 SPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRA 467
Query: 383 FKAGDKTLTPRKLSTRNRTPAKVEDAADSATKPENLSSKTRGSIPTDVEVLPTETEIHNE 442
+ + TP + R+R+PA + + P RG H+
Sbjct: 468 KRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTK-----RG---------------HSR 507
Query: 443 PFLTLWLTQVERKIQKDSLSK-PEKLGTTAGQMCSGLPGLS-SVDINNFGDSINESEGIP 500
W + R Q+ S+ P++ G + PG S S + G S + G
Sbjct: 508 SRSPQW--RRSRSAQRWGRSRSPQRRGRSRSPQ---RPGWSRSRNTQRRGRSRSARRG-- 560
Query: 501 LKRRRVSFGGHLRPELFDENLPPNTPLKRGEA----PTKRKSLVMHTPPVLKKIIKEQPQ 556
H R TP +RG + P +R+S P ++ P
Sbjct: 561 --------RSHSRSPATRGRSRSRTPARRGRSRSRTPARRRS--RSRTPTRRRSRSRTPA 610
Query: 557 PSGKQESGSEIHVEVKAQSLVISPPAPSPRKTPVASDQRR--RSCKTAPASSSKSQTEVP 614
G+ S + + +S P R++ S RR RS PA +S++ P
Sbjct: 611 RRGRSRSRTPARRRSRTRS-------PVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTP 663
Query: 615 KRGGRKSGNLPSKRVSISRSQHDILQMICSKR--RSGASEANLIVAKSWADVVKLGAKQT 672
R GR P++R SRS+ + R R G S + +V+ G +
Sbjct: 664 ARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSR--------SLVRRGRSHS 715
Query: 673 QTKVIKHGPQRSMNKRQRRPATPKKPVGEVHSQFSTGHANSPCTIIIGKAHTEKVHVPAR 732
+T + G S ++R+ + T SQ + +SP +K + +R
Sbjct: 716 RTPQ-RRGRSGSSSERKNKSRT---------SQRRSRSNSSP--------EMKKSRISSR 757
Query: 733 PYRVLNNFISNQK--MDFKEDLSGIAEMFKTPVKEQPQLTSTCHIAISNSENLLGKQFQG 790
R L++ S K + + LSG +P +Q T +S+ +
Sbjct: 758 RSRSLSSPRSKAKSRLSLRRSLSG-----SSPCPKQKSQTPPRRSRSGSSQPKAKSRTPP 812
Query: 791 TDSGEEPLLPTSESFGGNVFFSAQNAAKQPSDKCSASPPLRRQCIRENGNVAKTPRNTYK 850
S P + ++ ++Q S P ++ G++ N
Sbjct: 813 RRSRSSSSPPPKQ--------KSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQS 864
Query: 851 MTSLETKTSDTETEP---SKTVSTANRSGRSTEFRNIQKLPVESKSEETNTEIVECILKR 907
+T ++ +P S+T S + SG S P +S S ++ +
Sbjct: 865 VTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQ-------P 917
Query: 908 GQKATLLQQRREGEMKEIERPFETYKENIELKENDEKMKAMKRSRTWGQKCAPMSDLTDL 967
KA + ++R P + + SR + S D
Sbjct: 918 KVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDT 977
Query: 968 KSLPDTELMKDTARGQNLLQTQDHAKAPKSEKGKITKMPCQSLQPEPINTPTHTKQQLKA 1027
K P+T + + G + A+ P +K PC P+ + Q
Sbjct: 978 KVKPETP-PRQSHSGSISPYPKVKAQTPPGPSLSGSKSPC----PQE-KSKDSLVQSCPG 1031
Query: 1028 SLGK-VGVK------EELLAVGKF-TRTSGETTHTHREPAGDGKSIRTFKESPKQILDPA 1079
SL GVK E V + +T+ HR + ++ ESP
Sbjct: 1032 SLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQ 1091
Query: 1080 ARVTGMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACKSPPPESVDT 1139
G + +P E S + + F + M+ E++ + S P T
Sbjct: 1092 TSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYP----T 1147
Query: 1140 PTSTKQWPKRSLRKADVEEEFLAL-----RKLTPSAGKAMLTPKPAGGDEKDIKAF---M 1191
S + L A+ +E+ +AL +P K +P P + F +
Sbjct: 1148 VDSNSLLGQSRLETAESKEK-MALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTL 1206
Query: 1192 GTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLAGFKELFQTPGHTEELVAAGKTTKIPC 1251
TP ++ AG+ P +K Q +Q E+L E + P + + ++
Sbjct: 1207 RTPPRERSGAGSSPETKEQNSALPTSSQD-EELMEVVEKSEEPAGQILSHLSSELKEMST 1265
Query: 1252 DSPQSDPVDTPTSTKQRPKRSIRKADVEGELLACRNLMPSAGKAMHTPKPSVGEEKDIII 1311
+ +S P ++RP S+ + + +PS + P S E K++
Sbjct: 1266 SNFESSP-----EVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFS-PEHKEL-- 1317
Query: 1312 FVGTPVQKLDLTENL----TGSKRRPQTPKEEAQALEDLTG-FKELFQTPGHTEEAVAAG 1366
+P+++ L +G ++ EDL G F +T + +
Sbjct: 1318 -SNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQST 1376
Query: 1367 KTTKMPCESSPPESADTPTSTRRQ----------PKTPLEKRDVQKELSALKK-LTQTSG 1415
+++ P++ + + Q P+TP +R +K L +T
Sbjct: 1377 RSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPS 1436
Query: 1416 ETTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLEDLAGLKELFQ 1475
+ + PG D S R + + S G K P+T + G E
Sbjct: 1437 RRSRSGSSPGLRDGSGTPSRHSL------SGSSPGMKDIPRTPSR--------GRSECDS 1482
Query: 1476 TPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFA---LRKRTP 1532
+P +P +T + RS P PQ +RS + V+++ A L +R+
Sbjct: 1483 SP----EPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSR 1538
Query: 1533 SAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTP---KEKAQALEDLA 1589
S KP+ S Q+ +++ SK + +TP + ++ + ++
Sbjct: 1539 SGSSQELDVKPSAS------------PQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVD 1586
Query: 1590 GFKELFQTRGHTEES-MTNDKTAKVACKSSQPDPDKNPASSKRRLKTSLGKVGVKEELLA 1648
L R + S DK S D P + R + G +
Sbjct: 1587 SKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSK--G 1644
Query: 1649 VGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQLRTP--KGKSEV 1706
G + S T + P + + SP+ K + RTP + S
Sbjct: 1645 RGPSPEGSSSTESSPEHPPKSRTARRGSRSSPE-----------PKTKSRTPPRRRSSRS 1693
Query: 1707 PEDLAGFIELFQTPSHTKESMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKADTEE 1766
+L L + S T +R S P+ S P+P R +
Sbjct: 1694 SPELTRKARLSRRSRSASSSPETRSRTPPRHRRS-------PSVSSPEPAEKSRSSRRRR 1746
Query: 1767 EFLAFRKQTPSAGKAMHTPKP-AVGEEKDINTFLGT-PVQKLDQPGNLPGSNRRLQTRKE 1824
+ R +T S +PKP + + + T ++ D+ G+ ++RR Q +
Sbjct: 1747 SASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRS 1806
Query: 1825 KAQALEELTGFRELF-QTPCTDNPTTDEKTTKKILCKSPQSDPADTPTNTKQRP-KRSLK 1882
+++ G ++P + ++ ++P + + + T P KRS
Sbjct: 1807 RSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRS 1866
Query: 1883 KA 1884
+A
Sbjct: 1867 RA 1868
Score = 48.5 bits (114), Expect = 1e-04
Identities = 123/613 (20%), Positives = 215/613 (35%), Gaps = 93/613 (15%)
Query: 116 REQEPARR--VSRSSFSSDPDEKAQDS-KAYSKITEGKVSGN---PQVHIKNVKEDSTAD 169
+E+ P +R V+ + ++ +EK + +A I++ V G+ PQ + K+ +
Sbjct: 108 KEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEP 167
Query: 170 DSKDSVAQGTTNVHSSEHAGRNGRNAADPISGDFKEISSVKLVSRYGELKSVPTTQCLDN 229
S+ + +++ S + + D G E SS + + K ++
Sbjct: 168 PKPYSLVRESSSSRSPTPKQKKKKKKKD--RGRRSESSSPRRERKKSSKKKKHRSESESK 225
Query: 230 SKKNESPFWKLYESVKKELDVKSQKENVLQYCRK--------SGLQTDYATEKESADGLQ 281
+K+ SP K K + +S+ R+ S +D + + + +
Sbjct: 226 KRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAK 285
Query: 282 GETQLLVSRKSRPKSGGSGHAVAEPASPEQELDQNKGKGRDVESVQTPSKAVGASFPLYE 341
T L R P SG G A + P S Q PS
Sbjct: 286 THTTALAGRSPSPASGRRGEGDAPFSEP------------GTTSTQRPS----------- 322
Query: 342 PAKMKTPVQYSQQQNSPQKHKNKDLYT-TGRRESVNLGKSEGFKAGDKTLTPRKLSTRNR 400
+P ++Q +SP + K+KD + R S + +S G + P L
Sbjct: 323 -----SPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSS---TGPEPPAPTPLLAERH 374
Query: 401 ----TPAKVEDAADSATKPENLSSKTRG-SIPTDVEVLPTETEIHNEPFLTLWLTQVERK 455
P + P + +S TR S P E LP + + P + K
Sbjct: 375 GGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSP-----PSPQPTK 429
Query: 456 IQKDSLSKPEKLGTTAGQMCSGLPGLSSVDINNFGDSINESEGIPLKRRRVSFGGHLRPE 515
+ + + S PE PG S +I++ S N S G + +R H
Sbjct: 430 VSRHASSSPESPKPAPA------PG-SHREISSSPTSKNRSHG---RAKRDKSHSHTPSR 479
Query: 516 LFDENLPPNTPLK---RGEAPTKRKSLVMHTPPVLKKIIKEQPQPSGKQESGSEIHVEVK 572
+ P T + R PTKR +P + Q G+ S
Sbjct: 480 RMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRS---RSAQRWGRSRSPQRRGRSRS 536
Query: 573 AQSLVISPPAPSPRKTPVASDQRRRSCKTAPASSSKSQTEVPKRGGRKSGNLPSKRVSIS 632
Q S + R+ S +R RS +PA+ +S++ P R GR P++R S S
Sbjct: 537 PQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRS 596
Query: 633 RSQHDILQMICSKRRSGASEANLIVAKSWADVVKLGAKQTQTKVIKHGPQRSMNKRQRRP 692
R+ ++RRS + + G +++T + RS +R+ R
Sbjct: 597 RTP--------TRRRSRSRTP-----------ARRGRSRSRTPARRRSRTRSPVRRRSRS 637
Query: 693 ATPKKPVGEVHSQ 705
+P + G S+
Sbjct: 638 RSPARRSGRSRSR 650
Score = 48.5 bits (114), Expect = 1e-04
Identities = 110/597 (18%), Positives = 206/597 (34%), Gaps = 92/597 (15%)
Query: 2686 SETSGHTQESLT------AGKATKIPCESPPLEVVDTTASTKR-------HLRTRVQKVQ 2732
+ +SGH+ L+ AG ++ SP L+ V T S +R ++ + +
Sbjct: 1376 TRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTP 1435
Query: 2733 VKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRPRAPRE 2792
+ S G T + +G G+K + + + + S + P+ PR
Sbjct: 1436 SRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRP 1495
Query: 2793 SAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATS--SKRRPRTRAQKVE 2850
+++ P++ + + +SS + + A + +R +Q+++
Sbjct: 1496 RSRS---------PSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELD 1546
Query: 2851 VKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKE 2910
VK + + E + +D P + K +Q ++ E SR PR +
Sbjct: 1547 VKP--------SASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRS 1598
Query: 2911 KAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEP 2970
+ P E+ P +G+ S+P+ P + P + RR
Sbjct: 1599 GSSP--------EVKDKPRAAPRAQSGS----DSSPE--PKAPAPRALPRR-------SR 1637
Query: 2971 VGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDGSVTGTKRLRCMPAPEEIVEELPASKK 3030
G R P S S S P P K + GS R P P+ K
Sbjct: 1638 SGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGS-------RSSPEPKT---------K 1681
Query: 3031 QRVAPRARGKSSEPVVIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGIS 3090
R PR R S P + K L ++ + E S ++ + P K S
Sbjct: 1682 SRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRS 1741
Query: 3091 LRSRRQ------NKTEAEQQITEVFVLAERIEINRNEKKPMKTSPEMD----IQNPDDGA 3140
R RR T + + +R+ ++ +T+ D Q+
Sbjct: 1742 SRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRR 1801
Query: 3141 RKPIPRDKVTENKR-----CLRSARQNESSQPKVAEESGGQKSAKVLMQNQKGKGEAGNS 3195
++ R +VT +R RS + ESS+ G ++ + + + S
Sbjct: 1802 QRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSR----TS 1857
Query: 3196 DSMCLRSRKTKSQPAASTLESKSVQRVTRSVKRCAENP---KKAEDNVCVKKIRTRS 3249
+ RSR +++ PA ++R R +P +++ V + R+RS
Sbjct: 1858 PAPWKRSR-SRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRS 1913
Score = 42.7 bits (99), Expect = 0.006
Identities = 69/380 (18%), Positives = 134/380 (35%), Gaps = 23/380 (6%)
Query: 1335 TPKEEAQALEDLTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTS--TRRQPK 1392
TP+ E E K + +TP + + + +SP E +++ +S ++ + +
Sbjct: 1511 TPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTR 1570
Query: 1393 TPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSK 1452
TPL +R + ++ S + + P +DK A R + P +
Sbjct: 1571 TPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPR 1630
Query: 1453 RHPKTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSK 1512
P+ + E + + + +T + RS P+P S P +
Sbjct: 1631 ALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEP--KTKSRTPPRR 1688
Query: 1513 RSLRKVDVEEEFFALRKRTPSAGKA---------MHTPKPAVSGEKNIYAFMGTPVQKLD 1563
RS R L +R+ SA + H P+VS + + ++
Sbjct: 1689 RSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSA 1748
Query: 1564 LTENLTGSKRRLQTPKEKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPD 1623
+ + RR ++P K + L + ++R E++ T + + S
Sbjct: 1749 SSPRTKTTSRRGRSPSPKPRGL-------QRSRSRSRREKTRTTRRRDRSGSSQSTSRRR 1801
Query: 1624 KNPASSKRRLKTSLGKVGVKEELLAVGKLTQTSGETT--HTHTEPTGDGKSMKAFMESP- 1680
+ S R + G G A + ++TS + T PT +S +P
Sbjct: 1802 QRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPW 1861
Query: 1681 KQILDSAASLTGSKRQLRTP 1700
K+ A+ T + + RTP
Sbjct: 1862 KRSRSRASPATHRRSRSRTP 1881
Score = 35.8 bits (81), Expect = 0.71
Identities = 104/526 (19%), Positives = 179/526 (34%), Gaps = 74/526 (14%)
Query: 217 ELKSVPTTQCLDNSKKNESPFWKLYESVKKELDVKSQKENVLQYCRKSGLQTDYATE--- 273
EL P+ + S+ + SP D K++ L+ +SG + ++
Sbjct: 1544 ELDVKPSASPQERSESDSSP------------DSKAKTRTPLRQRSRSGSSPEVDSKSRL 1591
Query: 274 --KESADGLQGETQLLVSRKSRPKSGGSGH----AVAEPASPEQELDQNKGKGRDVESVQ 327
+ S G E + R +SG A A A P + + KGR
Sbjct: 1592 SPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRG----P 1647
Query: 328 TPSKAVGASFPLYEPAKMKTPVQYSQQQNSPQKHKNKDLYTTGRRESVNLGKSEGFKAGD 387
+P + P K +T + S+ P+ R S L +
Sbjct: 1648 SPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRS 1707
Query: 388 KTLTPRKLSTRNRTPAKVEDAAD-SATKPENLSSKTRGSIPTDVEVLPTETEIHNEPFLT 446
++ + TR+RTP + + S+ +P S +R T + P
Sbjct: 1708 RSASSSP-ETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSP--- 1763
Query: 447 LWLTQVERKIQKD-SLSKPEKLGTTAGQMCSGLPGLSSVDINNFGDSINESEGIPLKRRR 505
+ R +Q+ S S+ EK TT + SG S + + S +RRR
Sbjct: 1764 ---SPKPRGLQRSRSRSRREKTRTTRRRDRSG-----SSQSTSRRRQRSRSRSRVTRRRR 1815
Query: 506 VSFGGHLRPELFDENLPPNTPLKRGEA---PTKRK------------------SLVMH-- 542
G H R E+ ++ +RG + PT RK S H
Sbjct: 1816 GGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRR 1875
Query: 543 ----TPPVLKKIIKEQPQPSGKQESGSEIHVEVKAQSLVISPPAPSPRKTPVASDQRRRS 598
TP + ++ + + P ++ S S V + SP + ++ RRRS
Sbjct: 1876 SRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRS 1935
Query: 599 CKTAPASSSKSQTEVPKRGGRKSGNLPSKRVSISRSQHDILQMICSKRRSGASEANLIVA 658
P + +S++ P R+S + + V+ RS+ + + RS S +
Sbjct: 1936 RSRTPTTRRRSRSRTPPVTRRRSRS-RTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRS 1994
Query: 659 KSWADVVKLGAKQTQTKVIKHGPQRS-------MNKRQRRPATPKK 697
+S V +++T + RS R R P P+K
Sbjct: 1995 RSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRK 2040
Score = 35.4 bits (80), Expect = 0.93
Identities = 33/170 (19%), Positives = 61/170 (35%), Gaps = 19/170 (11%)
Query: 1374 ESSPPESADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTHTDKVPGGEDKSINA 1433
E PPE PT +R+ ++ S+ + +S ++ + S ++
Sbjct: 2592 EGRPPE----PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2647
Query: 1434 FRETAKQKLDPAASVTGSKRHP----KTKEKAQPLEDLAGLKELFQTPVCTDKPTTHEKT 1489
AK K+ P +++ +P++ L + L +PV +P+
Sbjct: 2648 SPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSP---- 2703
Query: 1490 TKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFFALRKRTPSAGKAMH 1539
QP P D +SS + R ++ D R+ TPS H
Sbjct: 2704 -------QPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRH 2746
Score = 32.3 bits (72), Expect = 7.9
Identities = 45/226 (19%), Positives = 79/226 (34%), Gaps = 38/226 (16%)
Query: 2171 AASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIACRSPQPDPVG 2230
++S + S +G + P++ LK + PT K R P+P
Sbjct: 2550 SSSSSSSGSSSSDSEGSSLPVQPEVALKRV-------PSPTPAPKEAVREGRPPEP---- 2598
Query: 2231 TPTIFKPQSKRSLRKADVEEESLALRKRTPSVGKAMDTPKPAGGDEKDMKAFMGTP---- 2286
TP K +S S + S + + S + + + P
Sbjct: 2599 TPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQA 2658
Query: 2287 VQKLDLPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGTDKPTTDEKTTKIACKSPQ 2346
+ K P P +R ++P++ +L D + L +P + SPQ
Sbjct: 2659 LPKPASPKKPPPGERRSRSPRKPIDSLRDS---RSLSYSPVERRRP-----------SPQ 2704
Query: 2347 PDPVDTPASTKQRPKRNLRKADVEEEFLALRKRTPSAGKAMDTPKP 2392
P P D +S+ +R R ++ D R+PS + +TP P
Sbjct: 2705 PSPRDQQSSSSERGSRRGQRGD---------SRSPSHKRRRETPSP 2741
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sapiens]
Length = 805
Score = 57.4 bits (137), Expect = 2e-07
Identities = 124/676 (18%), Positives = 241/676 (35%), Gaps = 98/676 (14%)
Query: 2588 SPPPELTDTATSTK---RCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIK 2644
+PP + +S + R P P K+ ++ AV+R T PA EG++
Sbjct: 193 APPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTL-----------PAWIREGLE 241
Query: 2645 VLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGF------------TELSETSGHT 2692
+++ +KK +E ++R + K++ + ED G ++ E
Sbjct: 242 KMEREKQKKLE--KERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTEN 299
Query: 2693 QESLTAGKATKIPCESPPLEVVDT--TASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETT 2750
E+ ++GK T+ P P E D T K + + K+ + T+ + T
Sbjct: 300 VEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLL---------TEILLDVT 350
Query: 2751 DADKEPAGEDKGIKALKESAKQTPAPAA--SVTGSRRRPRAPRESAQAIEDLAGFKDPAA 2808
D + +D KA K AKQ +A S+TG L G +
Sbjct: 351 DEEIYYVAKDAHRKATKAPAKQLAQSSALASLTG-----------------LGGLGGYGS 393
Query: 2809 GHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGET 2868
G +E+ +D + S + +D + R + A + KE+ L K + +
Sbjct: 394 GDSEDERSDRGS------ESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQ 447
Query: 2869 THTDKEPVGE--GKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQ 2926
T + + E K + R+ D + V +R P +P ++ ++ +
Sbjct: 448 TERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGR 507
Query: 2927 TPGHTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSK 2986
+ + + +++S TS+ T S S + + + P + +
Sbjct: 508 SRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSR---------SSSPKRKKRH 558
Query: 2987 SNTSLPPLPFKRGGGKDGS-----VTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKS 3041
S + P + +R + S + R++ + +++ +P +
Sbjct: 559 SRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRR 618
Query: 3042 SEPVVIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEA 3101
S +R+ R S R +++ + HK + E + RSR +K
Sbjct: 619 SRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRK 678
Query: 3102 EQQITEVFVLAERIEINRNEKKPMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQ 3161
++ +R E + E+K K S + D++ + R+ +
Sbjct: 679 KKDKEREREQDKRKEKQKREEKDFKFSSQ---------------DDRLKRKRESERTFSR 723
Query: 3162 NESSQPKVAEESGGQKSAKVLMQNQK---GKGEAGNSDSMCLRSRKTKSQPAASTLESKS 3218
+ S K+ Q S K ++ K G +G S S S K K S+S
Sbjct: 724 SGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRS 783
Query: 3219 VQRVTRSVKRCAENPK 3234
V++ RS K+ + K
Sbjct: 784 VEKSQRSGKKASRKHK 799
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sapiens]
Length = 805
Score = 57.4 bits (137), Expect = 2e-07
Identities = 124/676 (18%), Positives = 241/676 (35%), Gaps = 98/676 (14%)
Query: 2588 SPPPELTDTATSTK---RCPKTRPRKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIK 2644
+PP + +S + R P P K+ ++ AV+R T PA EG++
Sbjct: 193 APPQNRRERPSSFRDRQRSPIALPVKQEPPQIDAVKRRTL-----------PAWIREGLE 241
Query: 2645 VLKQRAKKKPNPVEEEPSRRRPRAPKEKAQPLEDLAGF------------TELSETSGHT 2692
+++ +KK +E ++R + K++ + ED G ++ E
Sbjct: 242 KMEREKQKKLE--KERMEQQRSQLSKKEKKATEDAEGGDGPRLPQRSKFDSDEEEEDTEN 299
Query: 2693 QESLTAGKATKIPCESPPLEVVDT--TASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETT 2750
E+ ++GK T+ P P E D T K + + K+ + T+ + T
Sbjct: 300 VEAASSGKVTRSPSPVPQEEHSDPEMTEEEKEYQMMLLTKMLL---------TEILLDVT 350
Query: 2751 DADKEPAGEDKGIKALKESAKQTPAPAA--SVTGSRRRPRAPRESAQAIEDLAGFKDPAA 2808
D + +D KA K AKQ +A S+TG L G +
Sbjct: 351 DEEIYYVAKDAHRKATKAPAKQLAQSSALASLTG-----------------LGGLGGYGS 393
Query: 2809 GHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGET 2868
G +E+ +D + S + +D + R + A + KE+ L K + +
Sbjct: 394 GDSEDERSDRGS------ESSDTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQ 447
Query: 2869 THTDKEPVGE--GKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQ 2926
T + + E K + R+ D + V +R P +P ++ ++ +
Sbjct: 448 TERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKEKEKQGR 507
Query: 2927 TPGHTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSK 2986
+ + + +++S TS+ T S S + + + P + +
Sbjct: 508 SRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSR---------SSSPKRKKRH 558
Query: 2987 SNTSLPPLPFKRGGGKDGS-----VTGTKRLRCMPAPEEIVEELPASKKQRVAPRARGKS 3041
S + P + +R + S + R++ + +++ +P +
Sbjct: 559 SRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRR 618
Query: 3042 SEPVVIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEA 3101
S +R+ R S R +++ + HK + E + RSR +K
Sbjct: 619 SRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRK 678
Query: 3102 EQQITEVFVLAERIEINRNEKKPMKTSPEMDIQNPDDGARKPIPRDKVTENKRCLRSARQ 3161
++ +R E + E+K K S + D++ + R+ +
Sbjct: 679 KKDKEREREQDKRKEKQKREEKDFKFSSQ---------------DDRLKRKRESERTFSR 723
Query: 3162 NESSQPKVAEESGGQKSAKVLMQNQK---GKGEAGNSDSMCLRSRKTKSQPAASTLESKS 3218
+ S K+ Q S K ++ K G +G S S S K K S+S
Sbjct: 724 SGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRS 783
Query: 3219 VQRVTRSVKRCAENPK 3234
V++ RS K+ + K
Sbjct: 784 VEKSQRSGKKASRKHK 799
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 56.6 bits (135), Expect = 4e-07
Identities = 124/683 (18%), Positives = 258/683 (37%), Gaps = 102/683 (14%)
Query: 2473 KTSRSSKQRLKIPLVKVDMKEEPL----------AVSKLTRTSGETTQTHTEPTGDSKSI 2522
+ +R ++R + ++ +EE L A + + +TT T+T+ GD ++
Sbjct: 36 EAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEA- 94
Query: 2523 KAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELF-----SAPGH-----T 2572
AF E +RR+ R +K ALE +F S P T
Sbjct: 95 -AFLERL------------ARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDT 141
Query: 2573 EESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVERLTQTSGQSTHT 2632
E+ T +K K + E+ +T T TK K R A E + +
Sbjct: 142 AENETTEKEEKSESRQERYEIEETETVTKSYQKNDWR-------DAEENKKEDKEKEEEE 194
Query: 2633 HKEPASGDEGIKVLKQRAKKKPNPVEEEP----------SRRRPRAPKEKAQPLEDLAGF 2682
++P G G ++ ++K +EE S P+ +E+ Q ++++
Sbjct: 195 EEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHH 254
Query: 2683 TELSETS------------GHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTRVQK 2730
++ E +E + A + KI E +E + A+ +R R ++
Sbjct: 255 EKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEER 314
Query: 2731 VQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRPRAP 2790
+++EE K + +++ A E++ + +KE K+ + +R
Sbjct: 315 ERMREEE---KRAAEERQRIKEEEKRAAEER--QRIKEEEKRAAEERQRIKEEEKRAAEE 369
Query: 2791 RESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQKVE 2850
R+ A+A E+ E++ +++ K + +LE+ + + + + +KVE
Sbjct: 370 RQRARAEEE------------EKAKVEEQ------KRNKQLEEKK-HAMQETKIKGEKVE 410
Query: 2851 VKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRAPKE 2910
K E V + + + GE KGTK + K + D + K+
Sbjct: 411 QKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKK 470
Query: 2911 KAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDS-----GKPLKISRRVLRA 2965
+P E++ SF + + G TE + + T K T ++ G+ ++ A
Sbjct: 471 DKEPKEEVKSFMDRKK--GFTEVKSQNG-EFMTHKLKHTENTFSRPGGRASVDTKEAEGA 527
Query: 2966 PKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDGSVTGTKRLRCMPAPEEIVEEL 3025
P+VE + R + + T + ++ ++ + + +++EE
Sbjct: 528 PQVEAGKRLEELR-----RRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEE 582
Query: 3026 PASKKQRVAPRARGKSSEPVVIMKRSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPE 3085
+KQ A R + E + + R A+ E +++ + + +K+ K P+
Sbjct: 583 EQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDDKKPFKC--FTPK 640
Query: 3086 NKGISLRSRRQNKTEAEQQITEV 3108
+ + R + ++ Q+ + V
Sbjct: 641 GSSLKIEERAEFLNKSVQKSSGV 663
Score = 43.5 bits (101), Expect = 0.003
Identities = 142/690 (20%), Positives = 251/690 (36%), Gaps = 113/690 (16%)
Query: 2365 RKADVEEEFLALRKRTPSAGKAMD----TPKPAVSDEKNINTFVETPVQKLDLLGNLPG- 2419
R+ +E L ++ S G+ D + +V DE+ T T V+ D L
Sbjct: 41 RRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERL 100
Query: 2420 SKRQPQTPKEKAEALEDLVGFKELF----------QTPGHTEESMTDDKI---------- 2459
++R+ + K EALE F + T E+ T +K
Sbjct: 101 ARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERY 160
Query: 2460 ----TEVSCKSPQPESFKTSRSSKQRLKIPLVKVDMKEE---------PLAVSKLTRTSG 2506
TE KS Q ++ + +K+ K + + K + + V + T S
Sbjct: 161 EIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQ 220
Query: 2507 ETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRTRKEKARALEDLVDFKELF 2566
E T + G S + +E ++ + ++ + KE+A A ++ +E
Sbjct: 221 EETVVMSLKNGQISSEEPKQEEERE--QGSDEISHHEKMEEEDKERAEAERARLEAEE-- 276
Query: 2567 SAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRPRKEVKEELSAVE-RLTQT 2625
E + +++ KI + E + A + +R R E +E + E R +
Sbjct: 277 ------RERIKAEQDKKIADERARIEAEEKAAAQER---ERREAEERERMREEEKRAAEE 327
Query: 2626 SGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSR-----RRPRAPKEKAQPLEDLA 2680
+ K A + IK ++RA ++ ++EE R +R RA +E+ +E+
Sbjct: 328 RQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQK 387
Query: 2681 GFTELSETSGHTQESLTAGKAT------KIPCESPPLEVVDTTASTKRHLRTRVQKVQVK 2734
+L E QE+ G+ K E E TA K+ + KVQ K
Sbjct: 388 RNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAK 447
Query: 2735 -----EEPSAVKFTQTSGETTDADKEPAGE-------DKGIKALK--------------E 2768
E+ K + E DKEP E KG +K E
Sbjct: 448 REKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTE 507
Query: 2769 SAKQTPAPAASVTGSRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSS 2828
+ P ASV E+ + +E+L + G T ES +K + +++
Sbjct: 508 NTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRR----GET-ESEEFEKLKQKQQEAA 562
Query: 2829 PELEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQP 2888
ELE+ + R + ++ + +++ A KL + +K + E + +
Sbjct: 563 LELEELKKKREERRKVLEEEEQRRKQEEADRKLRE------EEEKRRLKEEIERRRAEAA 616
Query: 2889 AKRKLDAEDVIGSRRQP---RAPKEKAQPLEDLASFQELSQTPGHTEELANGAA------ 2939
KR+ ED + ++P PK + +E+ A F S + + AA
Sbjct: 617 EKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKID 676
Query: 2940 ---DSFTSAPKQTPDSGKPLKISRRVLRAP 2966
+ +TSA + T S KP K + L P
Sbjct: 677 SRLEQYTSAIEGT-KSAKPTKPAASDLPVP 705
Score = 38.9 bits (89), Expect = 0.084
Identities = 112/596 (18%), Positives = 216/596 (36%), Gaps = 93/596 (15%)
Query: 2718 ASTKRHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPA 2777
A+ +R R R ++++ K+E ++ G+ TD + A + K + T
Sbjct: 37 AARERRRRARQERLRQKQEEESL------GQVTDQVEVNAQNSVPDEEAKTTTTNTQVEG 90
Query: 2778 ASVTG-----SRRRPRAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCK--SSPE 2830
+RR R + +A+E F DP D + +P + +
Sbjct: 91 DDEAAFLERLARREERRQKRLQEALERQKEF-DPTI--------TDASLSLPSRRMQNDT 141
Query: 2831 LEDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAK 2890
E+ T + + +R ++ E+ EE V K Q + + + + K + ++P +
Sbjct: 142 AENETTEKEEKSESRQERYEI-EETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKR 200
Query: 2891 RKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTP 2950
+ V + ++ + L + Q S+ P EE G+ D + K
Sbjct: 201 GSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGS-DEISHHEKMEE 259
Query: 2951 DSGKPLKISRRVLRAP-----KVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGGGKDGS 3005
+ + + R L A K E + R ++++ K+ +R ++
Sbjct: 260 EDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQ----ERERREAEERE 315
Query: 3006 VTGTKRLRCMPAPEEIVEE--LPASKKQRVAPRARGKSSEPVVIMKRSLRTSAKR----I 3059
+ R + I EE A ++QR+ + + E I + R + +R
Sbjct: 316 RMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARA 375
Query: 3060 EPAEELNSNDMKTNKE---------------------------------EHKLQDSV--- 3083
E E+ + K NK+ E KLQ +V
Sbjct: 376 EEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKK 435
Query: 3084 -PENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKKPMKT-------SPEMDIQN 3135
E KG ++++R+ E + + + E+I+ ++ K+ +K+ E+ QN
Sbjct: 436 QGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQN 495
Query: 3136 PDDGARKPIPRDKVTENKRCLRSARQNESSQPKVAEESGGQKSAKVLMQNQKGKGEAGNS 3195
+ K K TEN R S K AE + ++ K L + ++ +GE +
Sbjct: 496 GEFMTHKL----KHTENTFSRPGGR--ASVDTKEAEGAPQVEAGKRLEELRRRRGE---T 546
Query: 3196 DSMCLRSRKTKSQPAASTLESKSVQRVTRSVKRCAENPKKAEDNVCVKKIRTRSHR 3251
+S K K Q AA LE +R R K E ++ + +K+R +
Sbjct: 547 ESEEFEKLKQKQQEAALELEELKKKREERR-KVLEEEEQRRKQEEADRKLREEEEK 601
Score = 35.8 bits (81), Expect = 0.71
Identities = 52/235 (22%), Positives = 93/235 (39%), Gaps = 35/235 (14%)
Query: 1621 DPDKNPASSKRRLKT------------SLGKVGVKEELLAVGKLTQTSGETTHTHTEPTG 1668
D D+ A+ +RR + SLG+V + E+ A + +TT T+T+ G
Sbjct: 31 DDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEG 90
Query: 1669 DGKSMKAFMESPKQILDSAASLTGSKRQLRTPKGKSEVPE------DLAGFIELFQTPSH 1722
D ++ AF+E + +RQ R + E D + + + +
Sbjct: 91 DDEA--AFLE--------RLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQND 140
Query: 1723 TKESMTNEKTTKVSYRASQPDLVDTPTSSKPQPKRSLRKAD----TEEEFLAFRKQTPSA 1778
T E+ T EK K R + ++ +T T +K K R A+ ++E ++ P
Sbjct: 141 TAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKR 200
Query: 1779 GKAMHTPKPAVGEEKDINTFLGTPVQKLDQPGNLPGSNRRLQTRKEKAQALEELT 1833
G + EEK + T V L N S+ + +E+ Q +E++
Sbjct: 201 GSIGENQVEVMVEEKTTESQEETVVMSLK---NGQISSEEPKQEEEREQGSDEIS 252
Score = 34.7 bits (78), Expect = 1.6
Identities = 90/420 (21%), Positives = 159/420 (37%), Gaps = 49/420 (11%)
Query: 1360 EEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELSALKKLTQTSGETTH 1419
EE AA + + E + + + + E++ +E +K+ + + E
Sbjct: 298 EEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQ 357
Query: 1420 TDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLED--LAGLK------ 1471
K E+K R+ A+ + + A V KR+ + +EK +++ + G K
Sbjct: 358 RIKE---EEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIE 414
Query: 1472 -----------ELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDV 1520
+ QT V K EK TK+ + + D PT K + K K D
Sbjct: 415 GKWVNEKKAQEDKLQTAVL--KKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDK 472
Query: 1521 E--EEFFALRKRTPSAGKAMHTPKPAVSGEKNIYAFMGTPVQKLDLTENLTGSKRRLQTP 1578
E EE + R K T + +GE FM ++ + T + G + + T
Sbjct: 473 EPKEEVKSFMDR-----KKGFTEVKSQNGE-----FMTHKLKHTENTFSRPGGRASVDTK 522
Query: 1579 K-EKAQALEDLAGFKELFQTRGHTEESMTNDKTAKVACKSSQPDPDKNPASSKRRLKTSL 1637
+ E A +E +EL + RG TE K + + + K +R++
Sbjct: 523 EAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEE 582
Query: 1638 GKVGVKEELLAVGKLTQTSGETTHTHTEPTGDGKSMKAFMESPKQILDSAASLTGSKRQL 1697
+ +EE A KL + E + + + +A + K D L+ K+
Sbjct: 583 EQRRKQEE--ADRKLRE---EEEKRRLKEEIERRRAEAAEKRQKMPED---GLSDDKKPF 634
Query: 1698 R--TPKGKSEVPEDLAGFI-ELFQTPSHTKESMTNEKTTKVSYRASQ-PDLVDTPTSSKP 1753
+ TPKG S E+ A F+ + Q S K + +K+ R Q ++ S+KP
Sbjct: 635 KCFTPKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKP 694
Score = 34.3 bits (77), Expect = 2.1
Identities = 85/453 (18%), Positives = 165/453 (36%), Gaps = 43/453 (9%)
Query: 2832 EDTATSSKRRPRTRAQKVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKR 2891
++ + +RR R R +++ K+E ++G++T E + P E K T Q
Sbjct: 33 DEEEAARERRRRARQERLRQKQEEESLGQVTD-QVEVNAQNSVPDEEAKTTTTNTQ---- 87
Query: 2892 KLDAEDVIG-----SRRQPRAPKEKAQPLEDLASFQEL---SQTPGHTEELANGAADSFT 2943
++ +D +RR+ R K + LE F + + + N A++ T
Sbjct: 88 -VEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENET 146
Query: 2944 SAPKQTPDSGK---PLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTSLPPLPFKRGG 3000
+ ++ +S + ++ + V ++ + D + K + + P KRG
Sbjct: 147 TEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKP----KRGS 202
Query: 3001 GKDGSVTGTKRLRCMPAPEEIV----EELPASKKQRVAPRARGKSSEPVVIMKRSLRTSA 3056
+ V + + EE V + S ++ R + S+ + ++
Sbjct: 203 IGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDK 262
Query: 3057 KRIE------PAEELNSNDMKTNKE--EHKLQDSVPENKGISLRSRRQNKTEAEQQITEV 3108
+R E AEE + +K+ + + + E R RR+ + + E
Sbjct: 263 ERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEK 322
Query: 3109 FVLAERIEINRNEKKPMKTSPEMDIQNPDDGARKPIPRDKVTENKRC--LRSARQNESSQ 3166
ER I EK+ I+ + A + R K E + + AR E +
Sbjct: 323 RAAEERQRIKEEEKR--AAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEK 380
Query: 3167 PKVAEESGGQ--KSAKVLMQNQKGKGEAGNS--DSMCLRSRKTKSQPAASTLESKSVQRV 3222
KV E+ + + K MQ K KGE + + +K + + + K Q
Sbjct: 381 AKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKK--QGE 438
Query: 3223 TRSVKRCAENPKKAEDNVCVKKIRTRSHRDSED 3255
+ K A+ K ED KK + + +D
Sbjct: 439 EKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKD 471
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 56.2 bits (134), Expect = 5e-07
Identities = 151/719 (21%), Positives = 255/719 (35%), Gaps = 106/719 (14%)
Query: 2105 SPPPESMDTPTS----TRRRPKTPLGKRDIVEELSALKQLTQTTHTDKVPGDEDKGINVF 2160
SP P S PTS T TP + + E + L T K +G+
Sbjct: 197 SPTPASATAPTSQGIPTSDEESTPKKSKARILESITVSSLMATPQDPK-----GQGVGTG 251
Query: 2161 RETAKQKLDPAASVTGSKRQPRTPKGKAQPLEDLAGLKELFQTPICTDKPTTHEKTTKIA 2220
R +K ++ A G + P P + L + F TP + + + + IA
Sbjct: 252 RSASKLRI--AQVSPGPRDSPAFPDSPWRERVLAPILPDNFSTPTGSRTDSQSVRHSPIA 309
Query: 2221 CRSPQPDPVGTP--TIFKPQS-----KRSLRKADVEEESLALRKRTPSVGKAM---DTPK 2270
SP P + + K +S R L K EE + + R S + + + P+
Sbjct: 310 PSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAEEPAASGRIICHSYLERLLNVEVPQ 369
Query: 2271 PAGGDEKDMKAFMGTPVQKLD--LPGNLPGSKRWPQTPKEKAQALEDLAGFKELFQTPGT 2328
G ++K+ PV + +P N G+ WP E A + TP
Sbjct: 370 KVGSEQKEPPE-EAEPVAAAEPEVPEN-NGNNSWPHNDTEIANS------------TPNP 415
Query: 2329 DKPTTDEKTTKIACKSPQPDPVDTPASTKQ--RPKRNLRKADVE---EEFLALRKRTPSA 2383
+ +T + + D D P Q R KR+ ++A E E+ L + P
Sbjct: 416 KPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPR 475
Query: 2384 GKAMDTPKPAVSDEKNINTFVETPVQKLDLLGNLPGSKRQ------------PQTPKEK- 2430
K +P PA + + TF+ T VQ+ +L + R PKEK
Sbjct: 476 SKTPSSPCPASKVVRPLRTFLHT-VQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKE 534
Query: 2431 AEALEDLVGFKELFQTPGHTEESMTDDKITEVSCKSPQPESFKTSRSSKQRLKIPLVKVD 2490
+ LE+L +E Q E ++ EV K + E + +++R++
Sbjct: 535 RQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLK--REERLRKVLQARERVE------Q 586
Query: 2491 MKEE--PLAVSKLTRTSGETTQTHTEPTGDSKSIKAFKESPKQILDPAASVTGSRRQLRT 2548
MKEE K + +T + E + K+ K K + K++ + A R
Sbjct: 587 MKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKK--KAAAKKMEEVEAR--------RK 636
Query: 2549 RKEKARALEDLVDFKELFSAPGHTEESMTIDKNTKIPCKSPPPELTDTATSTKRCPKTRP 2608
++E+AR L L EE + K E A KR + R
Sbjct: 637 QEEEARRLRWL-----------QQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQRE 685
Query: 2609 RKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRR---- 2664
++ ++E ER Q + +E ++ + ++R + + E E + R
Sbjct: 686 QERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKE 745
Query: 2665 ---RPRAPKEKAQPLEDLAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTK 2721
R K+K + + LA E +E+ A KA + + V + A T
Sbjct: 746 QLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVD------VQSPACTS 799
Query: 2722 RHLRTRVQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASV 2780
+ + + K P S ++TD + P K + A+ TP A +
Sbjct: 800 YQMTPQGHRAPPKINPDNYGMDLNSDDSTDDEAHPR------KPIPTWARGTPLSQAII 852
Score = 36.2 bits (82), Expect = 0.54
Identities = 60/262 (22%), Positives = 99/262 (37%), Gaps = 50/262 (19%)
Query: 1008 QSLQPEPINTPTHTKQQLKASLGKVGVKEELLAVGKFTRTSGETTHTHREPAGDGK---- 1063
QS++ PI P+ Q+ A + K+E + R + +T EPA G+
Sbjct: 301 QSVRHSPI-APSSPSPQVLAQKYSLVAKQESVVRRASRRLAKKTAE---EPAASGRIICH 356
Query: 1064 -------------SIRTFKESPKQILDPAARV-------TGMKKWPRTPKEEAQSLEDLA 1103
+ + ++ P + +P A G WP E A S +
Sbjct: 357 SYLERLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNSWPHNDTEIANSTPNPK 416
Query: 1104 GFKELFQTPGPSEESMTDEKTTKIACKSPPPESVDTPTSTKQWPKRSLRKADVEEEFLAL 1163
+TP ++ + KT + PP+S S KQ ++ + D EE+ L
Sbjct: 417 PAASSPETPSAGQQ---EAKTDQADGPREPPQSARRKRSYKQ----AVSELD-EEQHLED 468
Query: 1164 RKLTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQL------------ 1211
+L P K +P PA + ++ F+ T VQ+ + T + R +
Sbjct: 469 EELQPPRSKTPSSPCPASKVVRPLRTFLHT-VQRNQMLMTPTSAPRSVMKSFIKRNTPLR 527
Query: 1212 QTPKEK-AQALEDLAGFKELFQ 1232
PKEK Q LE+L +E Q
Sbjct: 528 MDPKEKERQRLENLRRKEEAEQ 549
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 54.7 bits (130), Expect = 1e-06
Identities = 108/546 (19%), Positives = 203/546 (37%), Gaps = 86/546 (15%)
Query: 2609 RKEVKEELSAVERLTQTSGQSTHTHKEPASGDEGIKVLKQRAKKKPNPVEEEPSRRRPRA 2668
+K VK + A + +S+ + + +S DE K K K PV + + P
Sbjct: 147 QKGVKPQAKAA-KAPPKKAKSSDSDSDSSSEDEPPK----NQKPKITPVTVKAQTKAPPK 201
Query: 2669 PKEKAQPLED-LAGFTELSETSGHTQESLTAGKATKIPCESPPLEVVDTTASTKRHLRTR 2727
P A + + A + S +S + + KA P ++ P + V
Sbjct: 202 PARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQV------------- 248
Query: 2728 VQKVQVKEEPSAVKFTQTSGETTDADKEPAGEDKGIKALKESAKQTPAPAASVTGSRRRP 2787
V K VK + + + +S +++ ++E K+ K P P +SV
Sbjct: 249 VAKAPVKAATTPTRKSSSSEDSSSDEEEEQ---------KKPMKNKPGPYSSV------- 292
Query: 2788 RAPRESAQAIEDLAGFKDPAAGHTEESMTDDKTTKIPCKSSPELEDTATSSKRRPRTRAQ 2847
P SA + G + P ++ + + S + D+++ +++P T+A
Sbjct: 293 --PPPSAPPPKKSLGTQPPKKAVEKQQPVESS------EDSSDESDSSSEEEKKPPTKAV 344
Query: 2848 KVEVKEELLAVGKLTQTSGETTHTDKEPVGEGKGTKAFKQPAKRKLDAEDVIGSRRQPRA 2907
+ + K ++S +++ +D E A +PA ++ + + A
Sbjct: 345 VSKATTKPPPAKKAAESSSDSSDSDSSEDDE-----APSKPAGTTKNSSNKPAVTTKSPA 399
Query: 2908 PKEKAQPLEDLASFQELSQTPGHTEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAP- 2966
K A P + + Q+L + ++ S K+ + KP ++ L P
Sbjct: 400 VKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPA 459
Query: 2967 KVEPVGDVVSTRDPVKSQSK------SNTSLPPLPFKRGGG---------KDGSVTGTKR 3011
K P G S+ D S S+ S +++ P K GG K G +
Sbjct: 460 KQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNS 519
Query: 3012 LRCMPAPEEIVEELPASKKQRV-APRARGKSSEPVVIMKRSLRTSAKRIEPAEELNSNDM 3070
+ EE E+L R AP+A G S+ + K + +EE
Sbjct: 520 SSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTA--------QNGKAAKNSEE------ 565
Query: 3071 KTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVFVLAERIEINRNEKKPMKTSPE 3130
+EE K + +V +K SL+ R+QN+ E + + A++I++ P + E
Sbjct: 566 ---EEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQ----AKKIKLQTPNTFPKRKKGE 618
Query: 3131 MDIQNP 3136
+P
Sbjct: 619 KRASSP 624
Score = 42.4 bits (98), Expect = 0.008
Identities = 79/371 (21%), Positives = 141/371 (38%), Gaps = 50/371 (13%)
Query: 64 SSTNPTQVNGSVID----------EPVRLKHGDVITIIDRSFRYENESLQNGRKSTEFPR 113
++T PT+ + S D +P++ K G ++ S +SL T+ P+
Sbjct: 256 AATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSL-----GTQPPK 310
Query: 114 K-IREQEPARRVSRSSFSSD--------PDEKAQDSKAYSKITEGKVSGNPQVHIKNVKE 164
K + +Q+P SS SD P KA SKA +K K + +
Sbjct: 311 KAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSD--S 368
Query: 165 DSTADDSKDSVAQGTTNVHSSEHAGRNGRNAADPISGDFKEISS-VKLVSRYGELKSVPT 223
DS+ DD S GTT S++ A A P + + + KL++R + S
Sbjct: 369 DSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEE 428
Query: 224 TQCLDNSKKNESPFWKLYESVKKELDVKSQKENVLQYCRKSGLQTDYATEKESADGLQGE 283
++S E K+ + K + K+ + + + ++ S++ + +
Sbjct: 429 ----ESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEK 484
Query: 284 TQLLVSRKSRPKSGGSGHAVAEPASPEQELDQNKGKGR-------DVESVQTPSKAVGAS 336
T +K +P+ G A ++PAS KGK D S + K G
Sbjct: 485 TSKSAVKK-KPQKVAGGAAPSKPAS------AKKGKAESSNSSSSDDSSEEEEEKLKGKG 537
Query: 337 FPLYEPAKMKTPVQYSQQ-----QNSPQKHKNKDLYTTGRRESVNLGKSEGFKAGDKTLT 391
P + K + Q +NS ++ + K +S +L K + +A + T
Sbjct: 538 SPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAET 597
Query: 392 PRKLSTRNRTP 402
P+ + +TP
Sbjct: 598 PQAKKIKLQTP 608
Score = 40.4 bits (93), Expect = 0.029
Identities = 97/497 (19%), Positives = 167/497 (33%), Gaps = 68/497 (13%)
Query: 1059 AGDGKSIRTFKESPKQILDPAARVTGMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEES 1118
+ D S + ++ P + P +K + P + A++ +A K + S S
Sbjct: 166 SSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSS 225
Query: 1119 MTDEKTTKIACKSP-------------PPESVDTPTSTKQWPKRSLRKADVEEEFLALRK 1165
+D+ + A +P P ++ TPT + S +D EEE K
Sbjct: 226 SSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDS--SSDEEEEQKKPMK 283
Query: 1166 LTPSAGKAMLTPKPAGGDEKDIKAFMGTPVQKLDLAGTLPGSKRQLQTPKEKAQALEDLA 1225
P G P P+ P K L P + Q P E ++ D +
Sbjct: 284 NKP--GPYSSVPPPSA------------PPPKKSLGTQPPKKAVEKQQPVESSEDSSDES 329
Query: 1226 GFKELFQTPGHTEELVAAGKTTKIPCDSPQSDPVDTPTSTKQRPKRSIRKADVEGELLAC 1285
+ T+ +V+ T P D+ S + K
Sbjct: 330 DSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSK---------- 379
Query: 1286 RNLMPSAGKAMHTPKPSVGEEKDIIIFVGTPVQKLDLTENLTGSKRRPQTPKEEAQALED 1345
P+ + KP+V + + P Q + + L K + +EE+ + E+
Sbjct: 380 ----PAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEE 435
Query: 1346 LTGFKELFQTPGHTEEAVAAGKTTKMPCESSPPESADTPTSTRRQPKTPLEKRDVQKELS 1405
K++ T T+ A +P + +P S D S+ + E+ + + S
Sbjct: 436 -EKTKKMVAT---TKPKATAKAALSLPAKQAPQGSRD---SSSDSDSSSSEEEEEKTSKS 488
Query: 1406 ALKKLTQTSGETTHTDKVPGGEDKSINAFRETAKQKLDPAASVTGSKRHPKTKEKAQPLE 1465
A+KK Q KV GG S + A K A S S ++E+ + L+
Sbjct: 489 AVKKKPQ---------KVAGGAAPS-----KPASAKKGKAESSNSSSSDDSSEEEEEKLK 534
Query: 1466 DLAGLKELFQTPVCTDKPTTHEKTTKIACRSQPDPVDTPTSSKPQSKRSLRKVDVEEEFF 1525
+ Q P + K A S+ + + ++ SK K + E
Sbjct: 535 GKGSPRP--QAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNE-A 591
Query: 1526 ALRKRTPSAGK-AMHTP 1541
A TP A K + TP
Sbjct: 592 AKEAETPQAKKIKLQTP 608
Score = 32.3 bits (72), Expect = 7.9
Identities = 73/368 (19%), Positives = 129/368 (35%), Gaps = 59/368 (16%)
Query: 2883 KAFKQPAKRKLDAEDVIGSRRQPRAPKEKAQPLEDLASFQELSQTP------------GH 2930
K+ K P +RKL A + + + +A + ED + +E Q P G
Sbjct: 59 KSAKVP-ERKLQANGPVAKKAKKKASSSDS---EDSSEEEEEVQGPPAKKAAVPAKRVGL 114
Query: 2931 TEELANGAADSFTSAPKQTPDSGKPLKISRRVLRAPKVEPVGDVVSTRDPVKSQSKSNTS 2990
A A +S+ + + D + + + V + K + + S S S++S
Sbjct: 115 PPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSS 174
Query: 2991 LPPLPFKRGGGKDGSVTGTKRLRCMPAPEEIVEELPASKKQRVAPR-ARGKSSEPVVIMK 3049
P K K VT + + P P R AP+ A GK++
Sbjct: 175 SEDEPPKNQKPKITPVTVKAQTKAPPKPA------------RAAPKIANGKAASS----S 218
Query: 3050 RSLRTSAKRIEPAEELNSNDMKTNKEEHKLQDSVPENKGISLRSRRQNKTEAEQQITEVF 3109
S +S+ + EE + K + ++ P K + +R+ + +E E
Sbjct: 219 SSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPV-KAATTPTRKSSSSEDSSSDEE-- 275
Query: 3110 VLAERIEINRNEKKPMKTSPEMDIQNPDDGARKP------IPRDKVTENKRCLRSARQNE 3163
+KKPMK P P A P P K E ++ + S+ +
Sbjct: 276 ---------EEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSS 326
Query: 3164 SSQPKVAEESGGQKSAKVLMQ--------NQKGKGEAGNSDSMCLRSRKTKSQPAASTLE 3215
+EE + V+ + + + + +SDS + S+PA +T
Sbjct: 327 DESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKN 386
Query: 3216 SKSVQRVT 3223
S + VT
Sbjct: 387 SSNKPAVT 394
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.125 0.348
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 141,235,990
Number of Sequences: 37866
Number of extensions: 7563684
Number of successful extensions: 29367
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 571
Number of HSP's that attempted gapping in prelim test: 23326
Number of HSP's gapped (non-prelim): 5136
length of query: 3256
length of database: 18,247,518
effective HSP length: 121
effective length of query: 3135
effective length of database: 13,665,732
effective search space: 42842069820
effective search space used: 42842069820
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 72 (32.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.