Guide to the Human Genome
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Search of human proteins with 10047134

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10047134 cajalin 2 isoform c [Homo sapiens]
         (414 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10047134 cajalin 2 isoform c [Homo sapiens]                        852   0.0  
gi|50511945 cajalin 2 isoform a [Homo sapiens]                        731   0.0  
gi|140161500 ankyrin repeat and sterile alpha motif domain conta...   463   e-130
gi|50511947 cajalin 2 isoform b [Homo sapiens]                        416   e-116
gi|7705318 GULP, engulfment adaptor PTB domain containing 1 [Hom...    95   1e-19
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]       62   7e-10
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]       62   7e-10
gi|10863899 numb homolog (Drosophila)-like [Homo sapiens]              60   3e-09
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap...    60   5e-09
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap...    60   5e-09
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  60   5e-09
gi|54144629 numb homolog isoform 4 [Homo sapiens]                      59   8e-09
gi|20070356 numb homolog isoform 3 [Homo sapiens]                      59   8e-09
gi|132626790 low density lipoprotein receptor adaptor protein 1 ...    58   2e-08
gi|31317301 nitric oxide synthase 1 (neuronal) adaptor protein i...    57   4e-08
gi|54144627 numb homolog isoform 2 [Homo sapiens]                      57   4e-08
gi|54144625 numb homolog isoform 1 [Homo sapiens]                      57   4e-08
gi|194239668 SHC (Src homology 2 domain containing) transforming...    52   8e-07
gi|194239664 SHC (Src homology 2 domain containing) transforming...    52   8e-07
gi|194239662 SHC (Src homology 2 domain containing) transforming...    52   8e-07
gi|32261324 SHC (Src homology 2 domain containing) transforming ...    52   8e-07
gi|224586793 src homology 2 domain-containing transforming prote...    52   1e-06
gi|33350928 disabled homolog 1 [Homo sapiens]                          51   2e-06
gi|145312251 EPH receptor A6 isoform a [Homo sapiens]                  51   2e-06
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]             51   2e-06
gi|222446609 rai-like protein [Homo sapiens]                           49   6e-06
gi|148491082 disabled homolog 2 [Homo sapiens]                         49   8e-06
gi|32528301 EPH receptor B4 precursor [Homo sapiens]                   48   1e-05
gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapi...    47   3e-05
gi|71834346 sterile alpha motif domain containing 5 [Homo sapiens]     47   3e-05

>gi|10047134 cajalin 2 isoform c [Homo sapiens]
          Length = 414

 Score =  852 bits (2202), Expect = 0.0
 Identities = 414/414 (100%), Positives = 414/414 (100%)

Query: 1   MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN 60
           MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN
Sbjct: 1   MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN 60

Query: 61  GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD 120
           GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD
Sbjct: 61  GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD 120

Query: 121 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK 180
           SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK
Sbjct: 121 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK 180

Query: 181 PPRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKE 240
           PPRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKE
Sbjct: 181 PPRSITLRTGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKE 240

Query: 241 LRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNIS 300
           LRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNIS
Sbjct: 241 LRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNIS 300

Query: 301 CAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARK 360
           CAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARK
Sbjct: 301 CAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARK 360

Query: 361 GGHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF 414
           GGHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF
Sbjct: 361 GGHSSTLPESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHTEEALRKF 414


>gi|50511945 cajalin 2 isoform a [Homo sapiens]
          Length = 1248

 Score =  731 bits (1886), Expect = 0.0
 Identities = 377/443 (85%), Positives = 377/443 (85%), Gaps = 60/443 (13%)

Query: 32   TGPRCPVQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQR 91
            T PRCPVQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQR
Sbjct: 806  TRPRCPVQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQR 865

Query: 92   ILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELI 151
            ILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELI
Sbjct: 866  ILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELI 925

Query: 152  NVLKINLIGHRKRILASLGDRLHDD-------------------PPQKPP---------- 182
            NVLKINLIGHRKRILASLGDRLHDD                   PPQ  P          
Sbjct: 926  NVLKINLIGHRKRILASLGDRLHDDPPQKPPRSITLREPSGNHTPPQLSPSLSQSTYTTG 985

Query: 183  ---------------------------RSITLR----TGDWGEPSITLRPPNEATASTPV 211
                                       RS   R    TGDWGEPSITLRPPNEATASTPV
Sbjct: 986  GSLDVPHIIMQGDARRRRNENYFDDIPRSKLERQMAQTGDWGEPSITLRPPNEATASTPV 1045

Query: 212  QYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTI 271
            QYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTI
Sbjct: 1046 QYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTI 1105

Query: 272  ILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTA 331
            ILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTA
Sbjct: 1106 ILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTA 1165

Query: 332  FDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTLPESFENKPSKPIPKPRVSIRKSVD 391
            FDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTLPESFENKPSKPIPKPRVSIRKSVD
Sbjct: 1166 FDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTLPESFENKPSKPIPKPRVSIRKSVD 1225

Query: 392  LLHASHTGQEPSERHTEEALRKF 414
            LLHASHTGQEPSERHTEEALRKF
Sbjct: 1226 LLHASHTGQEPSERHTEEALRKF 1248


>gi|140161500 ankyrin repeat and sterile alpha motif domain containing
            1 [Homo sapiens]
          Length = 1134

 Score =  463 bits (1191), Expect = e-130
 Identities = 240/414 (57%), Positives = 293/414 (70%), Gaps = 59/414 (14%)

Query: 31   LTGPRCPVQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQ 90
            ++G R   Q+VG+WLESIGL QYE+ L+ NGFD+V F+GSNVME+QDL +IGI +  HR+
Sbjct: 691  ISGLRTLEQSVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISDPQHRR 750

Query: 91   RILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVEL 150
            ++LQA + LPK++ +G+DG  P SV  WLDS+ L DY  +FL +GY+S+D +K +WE+EL
Sbjct: 751  KLLQAARSLPKVKALGYDGNSPPSVPSWLDSLGLQDYVHSFLSSGYSSIDTVKNLWELEL 810

Query: 151  INVLKINLIGHRKRILASLGDRLHDDPPQKPPRSITLRT--------------------- 189
            +NVLK+ L+GHRKRI+ASL DR +++PPQKPPR   LR                      
Sbjct: 811  VNVLKVQLLGHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQTSSPLSQNDSCTGRS 870

Query: 190  -------GDWG--------------------------EPSITLRPPNEATASTPVQYWQH 216
                   GD G                          E  +TLRPP+ A    PVQ WQH
Sbjct: 871  ADLLLPPGDTGRRRHDSLHDPAAPSRAERFRIQEEHREAKLTLRPPSLAAPYAPVQSWQH 930

Query: 217  HPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVS 276
             PEKLIF+SC Y+A YLGSMLIK+LRGTESTQDACAKMR    KSTE MKK+PTIILS++
Sbjct: 931  QPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMR----KSTEHMKKIPTIILSIT 986

Query: 277  YKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNL 336
            YKGVKFIDA+NKN+IAEHEIRNISCAAQDPEDL TFAYITKDL+++HHYCHVF+  DVNL
Sbjct: 987  YKGVKFIDASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNL 1046

Query: 337  AYEIILTLGQAFEVAYQLALQARKG-GHSSTLPESFENKPSKPIPKPRVSIRKS 389
             YEIILTLGQAFEVAYQLALQA+K     ++  E  E K SKP+PKPRV +RKS
Sbjct: 1047 TYEIILTLGQAFEVAYQLALQAQKSRATGASAAEMIETKSSKPVPKPRVGVRKS 1100


>gi|50511947 cajalin 2 isoform b [Homo sapiens]
          Length = 510

 Score =  416 bits (1069), Expect = e-116
 Identities = 206/219 (94%), Positives = 209/219 (95%), Gaps = 8/219 (3%)

Query: 189 TGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQ 248
           TGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQ
Sbjct: 273 TGDWGEPSITLRPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQ 332

Query: 249 DACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPED 308
           DACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPED
Sbjct: 333 DACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPED 392

Query: 309 LSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTLP 368
           LSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTLP
Sbjct: 393 LSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARKGGHSSTLP 452

Query: 369 ESFENKPSKPIPKPRVSIRKSVDLLHASHTGQEPSERHT 407
           ESFENKPSKPIPKPRVSIRKSV +        +PSE+ T
Sbjct: 453 ESFENKPSKPIPKPRVSIRKSVQI--------DPSEQKT 483



 Score =  396 bits (1018), Expect = e-110
 Identities = 193/202 (95%), Positives = 193/202 (95%), Gaps = 5/202 (2%)

Query: 1   MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN 60
           MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN
Sbjct: 1   MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMAN 60

Query: 61  GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD 120
           GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD
Sbjct: 61  GFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLD 120

Query: 121 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK 180
           SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK
Sbjct: 121 SIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRLHDDPPQK 180

Query: 181 PPRSITLRTGDWGEPSITLRPP 202
           PPRSITLR     EPS    PP
Sbjct: 181 PPRSITLR-----EPSGNHTPP 197


>gi|7705318 GULP, engulfment adaptor PTB domain containing 1 [Homo
           sapiens]
          Length = 304

 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 53/156 (33%), Positives = 83/156 (53%), Gaps = 2/156 (1%)

Query: 203 NEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKST 262
           N A +    + W H PE L      Y A +LGS  +++ +GTE  +DA  K++       
Sbjct: 2   NRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKK 61

Query: 263 EQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSN 322
            + +K+P + L +S  GVK ++   K +    ++  IS  A D  D   F +I KD +SN
Sbjct: 62  SEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESN 121

Query: 323 HHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQA 358
            H C+VF +     A EI LT+GQAF++AY+  L++
Sbjct: 122 KHLCYVFDS--EKCAEEITLTIGQAFDLAYRKFLES 155


>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
          Length = 1120

 Score = 62.4 bits (150), Expect = 7e-10
 Identities = 39/129 (30%), Positives = 63/129 (48%), Gaps = 8/129 (6%)

Query: 39  QTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQL 98
           Q +  WL    L  Y  H +  G+D       + M  +DL  IG+   GHR++I   I  
Sbjct: 410 QAIHNWLSEFQLEGYTAHFLQAGYDVPTI---SRMTPEDLTAIGVTKPGHRKKIASEIAQ 466

Query: 99  LPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKI-WEVELINVLKIN 157
           L     +    Y PT + EWL ++ L  Y K  + +GY SM L+  + WE   +  + +N
Sbjct: 467 LSIAEWL--PSYIPTDLLEWLCALGLPQYHKQLVSSGYDSMGLVADLTWEE--LQEIGVN 522

Query: 158 LIGHRKRIL 166
            +GH+K+++
Sbjct: 523 KLGHQKKLM 531



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 19/61 (31%), Positives = 40/61 (65%), Gaps = 2/61 (3%)

Query: 43  QWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKM 102
           +WL ++GLPQY   L+++G+D++  +     E+  L EIG+   GH+++++  ++ L ++
Sbjct: 483 EWLCALGLPQYHKQLVSSGYDSMGLVADLTWEE--LQEIGVNKLGHQKKLMLGVKRLAEL 540

Query: 103 R 103
           R
Sbjct: 541 R 541


>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
          Length = 1202

 Score = 62.4 bits (150), Expect = 7e-10
 Identities = 39/129 (30%), Positives = 63/129 (48%), Gaps = 8/129 (6%)

Query: 39  QTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQL 98
           Q +  WL    L  Y  H +  G+D       + M  +DL  IG+   GHR++I   I  
Sbjct: 492 QAIHNWLSEFQLEGYTAHFLQAGYDVPTI---SRMTPEDLTAIGVTKPGHRKKIASEIAQ 548

Query: 99  LPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKI-WEVELINVLKIN 157
           L     +    Y PT + EWL ++ L  Y K  + +GY SM L+  + WE   +  + +N
Sbjct: 549 LSIAEWL--PSYIPTDLLEWLCALGLPQYHKQLVSSGYDSMGLVADLTWEE--LQEIGVN 604

Query: 158 LIGHRKRIL 166
            +GH+K+++
Sbjct: 605 KLGHQKKLM 613



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 19/61 (31%), Positives = 40/61 (65%), Gaps = 2/61 (3%)

Query: 43  QWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKM 102
           +WL ++GLPQY   L+++G+D++  +     E+  L EIG+   GH+++++  ++ L ++
Sbjct: 565 EWLCALGLPQYHKQLVSSGYDSMGLVADLTWEE--LQEIGVNKLGHQKKLMLGVKRLAEL 622

Query: 103 R 103
           R
Sbjct: 623 R 623


>gi|10863899 numb homolog (Drosophila)-like [Homo sapiens]
          Length = 609

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 38/132 (28%), Positives = 63/132 (47%), Gaps = 8/132 (6%)

Query: 200 RPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQ 259
           +P     AS P Q WQ   + +   +C +   YLG + ++E RG    +DA  K++A  +
Sbjct: 53  KPAYVPEASRPHQ-WQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGR 111

Query: 260 KSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDL 319
           KS +        +L VS  G++ +D   K+++ +  I  +S  A D      F+YI +D 
Sbjct: 112 KSVKS-------VLWVSADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDG 164

Query: 320 KSNHHYCHVFTA 331
            +    CH F A
Sbjct: 165 TTRRWICHCFLA 176


>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sapiens]
          Length = 1015

 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 30/72 (41%), Positives = 49/72 (68%), Gaps = 3/72 (4%)

Query: 98   LLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKIN 157
            LL +  P+G   Y   SV EWL++I++G YT+ F+ NGY+SMD + ++  +E +  L + 
Sbjct: 933  LLAEHSPLGSGAYR--SVGEWLEAIKMGRYTEIFMENGYSSMDAVAQV-TLEDLRRLGVT 989

Query: 158  LIGHRKRILASL 169
            L+GH+K+I+ SL
Sbjct: 990  LVGHQKKIMNSL 1001



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 18/59 (30%), Positives = 37/59 (62%), Gaps = 2/59 (3%)

Query: 39   QTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQ 97
            ++VG+WLE+I + +Y    M NG+ ++  +    +E  DL  +G+   GH+++I+ ++Q
Sbjct: 946  RSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLE--DLRRLGVTLVGHQKKIMNSLQ 1002


>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sapiens]
          Length = 1037

 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 30/72 (41%), Positives = 49/72 (68%), Gaps = 3/72 (4%)

Query: 98   LLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKIN 157
            LL +  P+G   Y   SV EWL++I++G YT+ F+ NGY+SMD + ++  +E +  L + 
Sbjct: 955  LLAEHSPLGSGAYR--SVGEWLEAIKMGRYTEIFMENGYSSMDAVAQV-TLEDLRRLGVT 1011

Query: 158  LIGHRKRILASL 169
            L+GH+K+I+ SL
Sbjct: 1012 LVGHQKKIMNSL 1023



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 18/59 (30%), Positives = 37/59 (62%), Gaps = 2/59 (3%)

Query: 39   QTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQ 97
            ++VG+WLE+I + +Y    M NG+ ++  +    +E  DL  +G+   GH+++I+ ++Q
Sbjct: 968  RSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLE--DLRRLGVTLVGHQKKIMNSLQ 1024


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 40/134 (29%), Positives = 67/134 (50%), Gaps = 12/134 (8%)

Query: 39  QTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQL 98
           + V QWL +  L  Y  + ++ G+D       + M  +DL  IG+   GHR++I   I  
Sbjct: 475 EAVSQWLTAFQLQLYAPNFISAGYDLPTI---SRMTPEDLTAIGVTKPGHRKKIAAEISG 531

Query: 99  L--PKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKI-WEVELINVLK 155
           L  P   P     + P ++A WL  I L  Y K  + NGY ++D +  I WE   +  + 
Sbjct: 532 LSIPDWLP----EHKPANLAVWLSMIGLAQYYKVLVDNGYENIDFITDITWED--LQEIG 585

Query: 156 INLIGHRKRILASL 169
           I  +GH+K+++ ++
Sbjct: 586 ITKLGHQKKLMLAV 599



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 24/67 (35%), Positives = 40/67 (59%), Gaps = 2/67 (2%)

Query: 44  WLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMR 103
           WL  IGL QY   L+ NG++N+ F+     E  DL EIGI   GH+++++ A++ L +++
Sbjct: 549 WLSMIGLAQYYKVLVDNGYENIDFITDITWE--DLQEIGITKLGHQKKLMLAVRKLAELQ 606

Query: 104 PIGHDGY 110
              +  Y
Sbjct: 607 KAEYAKY 613



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 22/89 (24%), Positives = 41/89 (46%), Gaps = 3/89 (3%)

Query: 100 PKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLI 159
           PK      +G    +V++WL + +L  Y   F+  GY    + +     E +  + +   
Sbjct: 462 PKKLEPASEGKSSEAVSQWLTAFQLQLYAPNFISAGYDLPTISR--MTPEDLTAIGVTKP 519

Query: 160 GHRKRILASL-GDRLHDDPPQKPPRSITL 187
           GHRK+I A + G  + D  P+  P ++ +
Sbjct: 520 GHRKKIAAEISGLSIPDWLPEHKPANLAV 548


>gi|54144629 numb homolog isoform 4 [Homo sapiens]
          Length = 592

 Score = 58.9 bits (141), Expect = 8e-09
 Identities = 37/125 (29%), Positives = 59/125 (47%), Gaps = 8/125 (6%)

Query: 207 ASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMK 266
           AS P Q WQ   E +    C +   YLG + + E RG    +DA  +++A  +K+ +   
Sbjct: 19  ASRPHQ-WQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKATGKKAVKA-- 75

Query: 267 KVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYC 326
                +L VS  G++ +D   K++I +  I  +S  A D      F+YI +D  +    C
Sbjct: 76  -----VLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWIC 130

Query: 327 HVFTA 331
           H F A
Sbjct: 131 HCFMA 135


>gi|20070356 numb homolog isoform 3 [Homo sapiens]
          Length = 640

 Score = 58.9 bits (141), Expect = 8e-09
 Identities = 37/125 (29%), Positives = 59/125 (47%), Gaps = 8/125 (6%)

Query: 207 ASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMK 266
           AS P Q WQ   E +    C +   YLG + + E RG    +DA  +++A  +K+ +   
Sbjct: 19  ASRPHQ-WQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKATGKKAVKA-- 75

Query: 267 KVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYC 326
                +L VS  G++ +D   K++I +  I  +S  A D      F+YI +D  +    C
Sbjct: 76  -----VLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWIC 130

Query: 327 HVFTA 331
           H F A
Sbjct: 131 HCFMA 135


>gi|132626790 low density lipoprotein receptor adaptor protein 1
           [Homo sapiens]
          Length = 308

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 36/122 (29%), Positives = 59/122 (48%), Gaps = 3/122 (2%)

Query: 232 YLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATNKNII 291
           YLG  L+++ +G E +  A  ++ A  + S ++++KV    L VS +G+   D     +I
Sbjct: 52  YLGMTLVEQPKGEELSAAAIKRIVATAKASGKKLQKVT---LKVSPRGIILTDNLTNQLI 108

Query: 292 AEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVA 351
               I  IS    D      FAYI +   +    CH F      +A  + LT+ QAF+VA
Sbjct: 109 ENVSIYRISYCTADKMHDKVFAYIAQSQHNQSLECHAFLCTKRKMAQAVTLTVAQAFKVA 168

Query: 352 YQ 353
           ++
Sbjct: 169 FE 170


>gi|31317301 nitric oxide synthase 1 (neuronal) adaptor protein
           isoform 1 [Homo sapiens]
          Length = 506

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 44/157 (28%), Positives = 69/157 (43%), Gaps = 19/157 (12%)

Query: 217 HPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVS 276
           H E        ++A Y+GS+ +           A  ++R   +    + KKV    + VS
Sbjct: 21  HNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVS---IMVS 77

Query: 277 YKGVKFIDATNKNI----------------IAEHEIRNISCAAQDPEDLSTFAYITKDLK 320
             GVK I    K +                + +  I  I   + D +DL  F+YI +D  
Sbjct: 78  VDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGA 137

Query: 321 SNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQ 357
           SN   C+VF +   + A  I+ T+GQAFEV ++L+LQ
Sbjct: 138 SNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQ 174


>gi|54144627 numb homolog isoform 2 [Homo sapiens]
          Length = 603

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 5/129 (3%)

Query: 207 ASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKST---- 262
           AS P Q WQ   E +    C +   YLG + + E RG    +DA  +++A  +       
Sbjct: 19  ASRPHQ-WQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFG 77

Query: 263 EQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSN 322
           +  KK    +L VS  G++ +D   K++I +  I  +S  A D      F+YI +D  + 
Sbjct: 78  KTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTR 137

Query: 323 HHYCHVFTA 331
              CH F A
Sbjct: 138 RWICHCFMA 146


>gi|54144625 numb homolog isoform 1 [Homo sapiens]
          Length = 651

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 5/129 (3%)

Query: 207 ASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQKST---- 262
           AS P Q WQ   E +    C +   YLG + + E RG    +DA  +++A  +       
Sbjct: 19  ASRPHQ-WQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFG 77

Query: 263 EQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSN 322
           +  KK    +L VS  G++ +D   K++I +  I  +S  A D      F+YI +D  + 
Sbjct: 78  KTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTR 137

Query: 323 HHYCHVFTA 331
              CH F A
Sbjct: 138 RWICHCFMA 146


>gi|194239668 SHC (Src homology 2 domain containing) transforming
           protein 1 isoform 4 [Homo sapiens]
          Length = 473

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 47/177 (26%), Positives = 83/177 (46%), Gaps = 32/177 (18%)

Query: 210 PVQYWQHHPEKLIFQSCDYKAFYLGSM-LIKELRG------TESTQDACA---------- 252
           P + W H  +K++     Y   Y+G + +++ +R       T+ T++A +          
Sbjct: 34  PTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVPGAK 93

Query: 253 ---KMRANCQK--------STEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC 301
              + R  C +        S  +   +P I L+VS   +  + A  K IIA H +++IS 
Sbjct: 94  GATRRRKPCSRPLSSILGRSNLKFAGMP-ITLTVSTSSLNLMAADCKQIIANHHMQSISF 152

Query: 302 AA-QDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQ 357
           A+  DP+     AY+ KD   N   CH+    +  LA ++I T+GQAFE+ ++  L+
Sbjct: 153 ASGGDPDTAEYVAYVAKD-PVNQRACHILECPE-GLAQDVISTIGQAFELRFKQYLR 207


>gi|194239664 SHC (Src homology 2 domain containing) transforming
           protein 1 isoform 3 [Homo sapiens]
          Length = 584

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 47/177 (26%), Positives = 83/177 (46%), Gaps = 32/177 (18%)

Query: 210 PVQYWQHHPEKLIFQSCDYKAFYLGSM-LIKELRG------TESTQDACA---------- 252
           P + W H  +K++     Y   Y+G + +++ +R       T+ T++A +          
Sbjct: 144 PTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVPGAK 203

Query: 253 ---KMRANCQK--------STEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC 301
              + R  C +        S  +   +P I L+VS   +  + A  K IIA H +++IS 
Sbjct: 204 GATRRRKPCSRPLSSILGRSNLKFAGMP-ITLTVSTSSLNLMAADCKQIIANHHMQSISF 262

Query: 302 AA-QDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQ 357
           A+  DP+     AY+ KD   N   CH+    +  LA ++I T+GQAFE+ ++  L+
Sbjct: 263 ASGGDPDTAEYVAYVAKD-PVNQRACHILECPE-GLAQDVISTIGQAFELRFKQYLR 317


>gi|194239662 SHC (Src homology 2 domain containing) transforming
           protein 1 isoform 1 [Homo sapiens]
          Length = 583

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 47/177 (26%), Positives = 83/177 (46%), Gaps = 32/177 (18%)

Query: 210 PVQYWQHHPEKLIFQSCDYKAFYLGSM-LIKELRG------TESTQDACA---------- 252
           P + W H  +K++     Y   Y+G + +++ +R       T+ T++A +          
Sbjct: 144 PTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVPGAK 203

Query: 253 ---KMRANCQK--------STEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC 301
              + R  C +        S  +   +P I L+VS   +  + A  K IIA H +++IS 
Sbjct: 204 GATRRRKPCSRPLSSILGRSNLKFAGMP-ITLTVSTSSLNLMAADCKQIIANHHMQSISF 262

Query: 302 AA-QDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQ 357
           A+  DP+     AY+ KD   N   CH+    +  LA ++I T+GQAFE+ ++  L+
Sbjct: 263 ASGGDPDTAEYVAYVAKD-PVNQRACHILECPE-GLAQDVISTIGQAFELRFKQYLR 317


>gi|32261324 SHC (Src homology 2 domain containing) transforming
           protein 1 isoform 2 [Homo sapiens]
          Length = 474

 Score = 52.4 bits (124), Expect = 8e-07
 Identities = 47/177 (26%), Positives = 83/177 (46%), Gaps = 32/177 (18%)

Query: 210 PVQYWQHHPEKLIFQSCDYKAFYLGSM-LIKELRG------TESTQDACA---------- 252
           P + W H  +K++     Y   Y+G + +++ +R       T+ T++A +          
Sbjct: 34  PTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVPGAK 93

Query: 253 ---KMRANCQK--------STEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISC 301
              + R  C +        S  +   +P I L+VS   +  + A  K IIA H +++IS 
Sbjct: 94  GATRRRKPCSRPLSSILGRSNLKFAGMP-ITLTVSTSSLNLMAADCKQIIANHHMQSISF 152

Query: 302 AA-QDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQ 357
           A+  DP+     AY+ KD   N   CH+    +  LA ++I T+GQAFE+ ++  L+
Sbjct: 153 ASGGDPDTAEYVAYVAKD-PVNQRACHILECPE-GLAQDVISTIGQAFELRFKQYLR 207


>gi|224586793 src homology 2 domain-containing transforming protein
           C3 [Homo sapiens]
          Length = 594

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 32/89 (35%), Positives = 50/89 (56%), Gaps = 3/89 (3%)

Query: 270 TIILSVSYKGVKFIDATNKNIIAEHEIRNISCAA-QDPEDLSTFAYITKDLKSNHHYCHV 328
           +I L++S   +      +K IIA H +R+IS A+  DP+     AY+ KD   N   CH+
Sbjct: 224 SISLTISTASLNLRTPDSKQIIANHHMRSISFASGGDPDTTDYVAYVAKD-PVNRRACHI 282

Query: 329 FTAFDVNLAYEIILTLGQAFEVAYQLALQ 357
               D  LA ++I ++GQAFE+ ++  LQ
Sbjct: 283 LECCD-GLAQDVIGSIGQAFELRFKQYLQ 310


>gi|33350928 disabled homolog 1 [Homo sapiens]
          Length = 555

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 34/127 (26%), Positives = 58/127 (45%), Gaps = 4/127 (3%)

Query: 228 YKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATN 287
           YKA  +G   +   RG +  QD+  K++     +  + +    I L++S+ G+K  D   
Sbjct: 42  YKAKLIGIDEVSAARGDKLCQDSMMKLKGVVAGARSKGEHKQKIFLTISFGGIKIFDEKT 101

Query: 288 KNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQA 347
             +   H +  IS  A+D  D   F Y+    + NH +  + TA     A  +IL L   
Sbjct: 102 GALQHHHAVHEISYIAKDITDHRAFGYVC-GKEGNHRFVAIKTA---QAAEPVILDLRDL 157

Query: 348 FEVAYQL 354
           F++ Y+L
Sbjct: 158 FQLIYEL 164


>gi|145312251 EPH receptor A6 isoform a [Homo sapiens]
          Length = 1130

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 32/87 (36%), Positives = 47/87 (54%), Gaps = 4/87 (4%)

Query: 27   PLHPLTGPRCPV-QTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILN 85
            P  P   P  P+  TVG WL+SI + QY+N+ +A GF     +    M   D+  IG++ 
Sbjct: 1045 PESPGEVPEYPLFVTVGDWLDSIKMGQYKNNFVAAGFTTFDLISR--MSIDDIRRIGVIL 1102

Query: 86   SGHRQRILQAIQLLP-KMRPIGHDGYH 111
             GH++RI+ +IQ L   M  I   G+H
Sbjct: 1103 IGHQRRIVSSIQTLRLHMMHIQEKGFH 1129



 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 24/62 (38%), Positives = 43/62 (69%), Gaps = 2/62 (3%)

Query: 114  SVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGD-R 172
            +V +WLDSI++G Y   F+  G+T+ DL+ ++  ++ I  + + LIGH++RI++S+   R
Sbjct: 1059 TVGDWLDSIKMGQYKNNFVAAGFTTFDLISRM-SIDDIRRIGVILIGHQRRIVSSIQTLR 1117

Query: 173  LH 174
            LH
Sbjct: 1118 LH 1119


>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
          Length = 998

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 22/59 (37%), Positives = 42/59 (71%), Gaps = 1/59 (1%)

Query: 113 TSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGD 171
           T+V +WLD+I++G Y ++F+  G+ S DL+ ++   +L+ +  + L GH+K+IL+S+ D
Sbjct: 928 TTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRI-GVTLAGHQKKILSSIQD 985



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 21/58 (36%), Positives = 37/58 (63%), Gaps = 2/58 (3%)

Query: 40  TVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQ 97
           TVG WL++I + +Y+   ++ GF +   +    M  +DLL IG+  +GH+++IL +IQ
Sbjct: 929 TVGDWLDAIKMGRYKESFVSAGFASFDLVAQ--MTAEDLLRIGVTLAGHQKKILSSIQ 984


>gi|222446609 rai-like protein [Homo sapiens]
          Length = 630

 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 29/88 (32%), Positives = 51/88 (57%), Gaps = 3/88 (3%)

Query: 271 IILSVSYKGVKFIDATNKNIIAEHEIRNISCAA-QDPEDLSTFAYITKDLKSNHHYCHVF 329
           I L++S   +  ++  N+ IIA H +++IS A+  DP+     AY+ KD   N   CH+ 
Sbjct: 262 IKLTISTCSLTLMNLDNQQIIANHHMQSISFASGGDPDTTDYVAYVAKD-PVNQRACHIL 320

Query: 330 TAFDVNLAYEIILTLGQAFEVAYQLALQ 357
              +  +A ++I T+GQAFE+ ++  L+
Sbjct: 321 ECHN-GMAQDVISTIGQAFELRFKQYLK 347


>gi|148491082 disabled homolog 2 [Homo sapiens]
          Length = 770

 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 33/127 (25%), Positives = 57/127 (44%), Gaps = 4/127 (3%)

Query: 228 YKAFYLGSMLIKELRGTESTQDACAKMRANCQKSTEQMKKVPTIILSVSYKGVKFIDATN 287
           YKA  +G   + + RG + +QD+  K++        Q +    I +++S  G+K ID   
Sbjct: 50  YKAKLIGIDDVPDARGDKMSQDSMMKLKGMAAAGRSQGQHKQRIWVNISLSGIKIIDEKT 109

Query: 288 KNIIAEHEIRNISCAAQDPEDLSTFAYITKDLKSNHHYCHVFTAFDVNLAYEIILTLGQA 347
             I  EH +  IS  A+D  D   F Y+    +  H +  + T      A  +++ L   
Sbjct: 110 GVIEHEHPVNKISFIARDVTDNRAFGYVCGG-EGQHQFFAIKTG---QQAEPLVVDLKDL 165

Query: 348 FEVAYQL 354
           F+V Y +
Sbjct: 166 FQVIYNV 172


>gi|32528301 EPH receptor B4 precursor [Homo sapiens]
          Length = 987

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 27/85 (31%), Positives = 45/85 (52%), Gaps = 6/85 (7%)

Query: 29  HPLTGPRCP----VQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGIL 84
           HPL   R P      +VG+WL +I + +YE    A GF + + +    +  +DLL IG+ 
Sbjct: 896 HPLLDQRQPHYSAFGSVGEWLRAIKMGRYEESFAAAGFGSFELVSQ--ISAEDLLRIGVT 953

Query: 85  NSGHRQRILQAIQLLPKMRPIGHDG 109
            +GH+++IL ++Q +      G  G
Sbjct: 954 LAGHQKKILASVQHMKSQAKPGTPG 978



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 24/68 (35%), Positives = 40/68 (58%), Gaps = 1/68 (1%)

Query: 114 SVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRILASLGDRL 173
           SV EWL +I++G Y ++F   G+ S +L+ +I   +L+ +  + L GH+K+ILAS+    
Sbjct: 911 SVGEWLRAIKMGRYEESFAAAGFGSFELVSQISAEDLLRI-GVTLAGHQKKILASVQHMK 969

Query: 174 HDDPPQKP 181
               P  P
Sbjct: 970 SQAKPGTP 977


>gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo
           sapiens]
          Length = 1005

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 23/64 (35%), Positives = 38/64 (59%), Gaps = 1/64 (1%)

Query: 106 GHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRI 165
           G  G    +V +WLDSI +G Y   F   GY+S+ ++ ++   + +  L I L+GH+K+I
Sbjct: 926 GSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLGMVLRM-NAQDVRALGITLMGHQKKI 984

Query: 166 LASL 169
           L S+
Sbjct: 985 LGSI 988



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 22/60 (36%), Positives = 37/60 (61%), Gaps = 2/60 (3%)

Query: 40  TVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLL 99
           TVG WL+SI + +Y +H  A G+ ++  +    M  QD+  +GI   GH+++IL +IQ +
Sbjct: 934 TVGDWLDSIRMGRYRDHFAAGGYSSLGMVLR--MNAQDVRALGITLMGHQKKILGSIQTM 991


>gi|71834346 sterile alpha motif domain containing 5 [Homo
          sapiens]
          Length = 173

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 23/59 (38%), Positives = 38/59 (64%), Gaps = 2/59 (3%)

Query: 41 VGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLL 99
          V +WL+++ LPQY    + NG+D+++      + D DL  IG+L   HR+RIL+A++ L
Sbjct: 6  VYEWLKALQLPQYAESFVDNGYDDLEV--CKQIGDPDLDAIGVLAPAHRRRILEAVRRL 62



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 14/94 (14%)

Query: 115 VAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINVLKINLIGHRKRIL-------- 166
           V EWL +++L  Y ++F+ NGY  +++ K+I + +L + + +    HR+RIL        
Sbjct: 6   VYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDL-DAIGVLAPAHRRRILEAVRRLRE 64

Query: 167 -----ASLGDRLHDDPPQKPPRSITLRTGDWGEP 195
                A L   L   P    P +  + TG  GEP
Sbjct: 65  QDANAAGLYFTLEPQPAPPGPPADAVPTGRRGEP 98


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,775,584
Number of Sequences: 37866
Number of extensions: 763632
Number of successful extensions: 2308
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 2141
Number of HSP's gapped (non-prelim): 133
length of query: 414
length of database: 18,247,518
effective HSP length: 105
effective length of query: 309
effective length of database: 14,271,588
effective search space: 4409920692
effective search space used: 4409920692
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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