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Search of human proteins with 18104967
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18104967 prostaglandin-endoperoxide synthase 1 isoform 1
precursor [Homo sapiens]
(599 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18104967 prostaglandin-endoperoxide synthase 1 isoform 1 prec... 1254 0.0
gi|18104969 prostaglandin-endoperoxide synthase 1 isoform 2 prec... 1164 0.0
gi|4506265 prostaglandin-endoperoxide synthase 2 precursor [Homo... 787 0.0
gi|109150416 peroxidasin [Homo sapiens] 63 9e-10
gi|126517478 peroxidasin homolog-like [Homo sapiens] 54 5e-07
gi|20149640 dual oxidase 1 precursor [Homo sapiens] 52 2e-06
gi|28872751 dual oxidase 1 precursor [Homo sapiens] 52 2e-06
gi|28558982 thyroid peroxidase isoform a [Homo sapiens] 50 6e-06
gi|28558984 thyroid peroxidase isoform b [Homo sapiens] 50 6e-06
gi|28558988 thyroid peroxidase isoform d [Homo sapiens] 50 6e-06
gi|231569458 lactoperoxidase isoform 3 preproprotein [Homo sapiens] 50 8e-06
gi|40549418 lactoperoxidase isoform 1 preproprotein [Homo sapiens] 50 8e-06
gi|132566532 dual oxidase 2 precursor [Homo sapiens] 45 1e-04
gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens] 45 1e-04
gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens] 45 1e-04
gi|4557759 myeloperoxidase [Homo sapiens] 44 3e-04
gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens] 44 3e-04
gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens] 44 3e-04
gi|4557679 jagged 1 precursor [Homo sapiens] 43 7e-04
gi|41327708 crumbs homolog 1 precursor [Homo sapiens] 42 0.001
gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens] 41 0.003
gi|134244285 Notch homolog 3 [Homo sapiens] 40 0.008
gi|24041035 notch 2 preproprotein [Homo sapiens] 40 0.008
gi|148833508 notch1 preproprotein [Homo sapiens] 39 0.010
gi|110735443 delta-like 1 [Homo sapiens] 39 0.014
gi|4503595 eosinophil peroxidase [Homo sapiens] 39 0.018
gi|38348304 von Willebrand factor A domain containing 2 [Homo sa... 39 0.018
gi|4759146 slit homolog 2 [Homo sapiens] 38 0.023
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 38 0.030
gi|11321571 slit homolog 3 [Homo sapiens] 37 0.040
>gi|18104967 prostaglandin-endoperoxide synthase 1 isoform 1
precursor [Homo sapiens]
Length = 599
Score = 1254 bits (3245), Expect = 0.0
Identities = 599/599 (100%), Positives = 599/599 (100%)
Query: 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTR 60
MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTR
Sbjct: 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTR 60
Query: 61 TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS 120
TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS
Sbjct: 61 TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS 120
Query: 121 NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF 180
NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF
Sbjct: 121 NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF 180
Query: 181 LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ 240
LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ
Sbjct: 181 LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ 240
Query: 241 YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY 300
YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY
Sbjct: 241 YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY 300
Query: 301 ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF 360
ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF
Sbjct: 301 ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF 360
Query: 361 DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEA 420
DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEA
Sbjct: 361 DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEA 420
Query: 421 LVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL 480
LVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL
Sbjct: 421 LVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL 480
Query: 481 VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS 540
VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS
Sbjct: 481 VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS 540
Query: 541 PEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 599
PEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
Sbjct: 541 PEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 599
>gi|18104969 prostaglandin-endoperoxide synthase 1 isoform 2
precursor [Homo sapiens]
Length = 562
Score = 1164 bits (3012), Expect = 0.0
Identities = 562/599 (93%), Positives = 562/599 (93%), Gaps = 37/599 (6%)
Query: 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTR 60
MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTR
Sbjct: 1 MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTR 60
Query: 61 TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS 120
TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS
Sbjct: 61 TGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRS 120
Query: 121 NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF 180
NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF
Sbjct: 121 NLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRF 180
Query: 181 LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ 240
LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ
Sbjct: 181 LLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQ 240
Query: 241 YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY 300
YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY
Sbjct: 241 YQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLY 300
Query: 301 ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF 360
ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF
Sbjct: 301 ATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKF 360
Query: 361 DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEA 420
DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFK
Sbjct: 361 DPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFK------------------------- 395
Query: 421 LVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL 480
IGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL
Sbjct: 396 ------------IGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL 443
Query: 481 VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS 540
VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS
Sbjct: 444 VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICS 503
Query: 541 PEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 599
PEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
Sbjct: 504 PEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL 562
>gi|4506265 prostaglandin-endoperoxide synthase 2 precursor [Homo
sapiens]
Length = 604
Score = 787 bits (2033), Expect = 0.0
Identities = 357/552 (64%), Positives = 446/552 (80%), Gaps = 1/552 (0%)
Query: 33 NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLL 92
NPCC +PCQ++G+C+ G D+Y+CDCTRTG+ G NC+ P T ++ L+P+P+ H++L
Sbjct: 19 NPCCSHPCQNRGVCMSVGFDQYKCDCTRTGFYGENCSTPEFLTRIKLFLKPTPNTVHYIL 78
Query: 93 THGRWFWEFVN-ATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRIL 151
TH + FW VN F+R +M VLT RS+LI SPPTYN+ + Y SWE+FSN+SYYTR L
Sbjct: 79 THFKGFWNVVNNIPFLRNAIMSYVLTSRSHLIDSPPTYNADYGYKSWEAFSNLSYYTRAL 138
Query: 152 PSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKT 211
P VP DCPTP+G KGKKQLPD+ + + LLRRKFIPDPQG+N+MFAFFAQHFTHQFFKT
Sbjct: 139 PPVPDDCPTPLGVKGKKQLPDSNEIVEKLLLRRKFIPDPQGSNMMFAFFAQHFTHQFFKT 198
Query: 212 SGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVL 271
K GP FT LGHGVDL HIYG+ L RQ +LRLFKDGK+KYQ++DGEMYPP+V++
Sbjct: 199 DHKRGPAFTNGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQIIDGEMYPPTVKDTQAE 258
Query: 272 MHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTT 331
M YP +P + AVGQEVFGL+PGLM+YAT+WLREHNRVCD+LK EHP WGDEQLFQT+
Sbjct: 259 MIYPPQVPEHLRFAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTS 318
Query: 332 RLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMP 391
RLILIGETIKIVIE+YVQ LSGY +LKFDPELLF QFQY+NRIA EFN LYHWHPL+P
Sbjct: 319 RLILIGETIKIVIEDYVQHLSGYHFKLKFDPELLFNKQFQYQNRIAAEFNTLYHWHPLLP 378
Query: 392 DSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVI 451
D+F++ Q+Y+Y+QF++N S+L+++G+ V++F+RQIAGR+ GGRN+ + V+ I
Sbjct: 379 DTFQIHDQKYNYQQFIYNNSILLEHGITQFVESFTRQIAGRVAGGRNVPPAVQKVSQASI 438
Query: 452 RESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKC 511
+SR+M+ Q FNEYRKRF +KPY SF+EL GEKEM+AELE LYGDIDA+E YP LL+EK
Sbjct: 439 DQSRQMKYQSFNEYRKRFMLKPYESFEELTGEKEMSAELEALYGDIDAVELYPALLVEKP 498
Query: 512 HPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNT 571
P++IFGE+M+E+GAPFSLKGL+GN ICSP YWKPSTFGGEVGF I+ TA+++ L+C N
Sbjct: 499 RPDAIFGETMVEVGAPFSLKGLMGNVICSPAYWKPSTFGGEVGFQIINTASIQSLICNNV 558
Query: 572 KTCPYVSFRVPD 583
K CP+ SF VPD
Sbjct: 559 KGCPFTSFSVPD 570
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 62.8 bits (151), Expect = 9e-10
Identities = 77/336 (22%), Positives = 141/336 (41%), Gaps = 41/336 (12%)
Query: 296 GLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYF 355
GL TLW REHNR+ L +P W + ++ TR I+ E I + ++ ++ G
Sbjct: 983 GLTSMHTLWFREHNRIATELLKLNPHWDGDTIYYETRKIVGAEIQHITYQHWLPKILGEV 1042
Query: 356 LQLK------FDPELLFGVQFQYRNRIAMEFNHLYHWHPL---MPDSFKVGSQEY-SYEQ 405
+DP + G+ F A F H +PL + ++F+ +Q++ +
Sbjct: 1043 GMRTLGEYHGYDPGINAGI-FNAFATAAFRFGHTL-VNPLLYRLDENFQPIAQDHLPLHK 1100
Query: 406 FLFNTSMLVDYGVEALVDAFSRQIAGRIGGGR---------------NMDHHI-LHVAVD 449
F+ +V+ E +D R + G G R +M H + L +A
Sbjct: 1101 AFFSPFRIVN---EGGIDPLLRGLFGVAGKMRVPSQLLNTELTERLFSMAHTVALDLAAI 1157
Query: 450 VIRESREMRLQPFNEYRKRFGMKPYTSFQELVGE---KEMAAELEELYGDIDALEFYPGL 506
I+ R+ + P+++YR + +F++L E E+ +L+ LYG ++ +P L
Sbjct: 1158 NIQRGRDHGIPPYHDYRVYCNLSAAHTFEDLKNEIKNPEIREKLKRLYGSTLNIDLFPAL 1217
Query: 507 LLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKL 566
++E P S G +++ + + + G+ + Y P F +K +L ++
Sbjct: 1218 VVEDLVPGSRLGPTLMCLLSTQFKRLRDGDRLW---YENPGVF-SPAQLTQIKQTSLARI 1273
Query: 567 VCLNTKTCPYVS---FRVPDASQDDGPAVERPSTEL 599
+C N V FRV + G E P +L
Sbjct: 1274 LCDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDL 1309
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 53.5 bits (127), Expect = 5e-07
Identities = 74/340 (21%), Positives = 137/340 (40%), Gaps = 61/340 (17%)
Query: 227 VDLGHIYGDNLERQYQLRLFKDGKLKYQVLD-GEMYPPSVEEAPVLMHYPRGIPPQSQMA 285
+D ++YG + ER+ Q +D + +L G +PPS + L+ + G PP
Sbjct: 894 IDGSNVYGSS-ERESQA--LRDPSVPRGLLKTGFPWPPSGKP---LLPFSTG-PPTECAR 946
Query: 286 VGQEVFGLLPG---------LMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILI 336
QE L G L TLW REHNRV L A +P W ++Q R I+
Sbjct: 947 QEQESPCFLAGDHRANEHLALAAMHTLWFREHNRVATELSALNPHWEGNTVYQEARKIVG 1006
Query: 337 GETIKIVIEEYV---------QQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNH----- 382
E I ++ + L GY ++P + G+ + A F H
Sbjct: 1007 AELQHITYSHWLPKVLGDPGTRMLRGY---RGYNPNVNAGIINSFAT-AAFRFGHTLINP 1062
Query: 383 -LYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDH 441
LY + + + + + + LF+ S ++ E +D R + G R +
Sbjct: 1063 ILYRLNATLGE---ISEGHLPFHKALFSPSRIIK---EGGIDPVLRGLFGVAAKWRAPSY 1116
Query: 442 HI----------------LHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQEL---VG 482
+ + A +I+ R+ + P+ ++R + +F++L +
Sbjct: 1117 LLSPELTQRLFSAAYSAAVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLQNEIK 1176
Query: 483 EKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMI 522
+ E+ +L +LYG ++ +P L++E P + G +++
Sbjct: 1177 DSEIRQKLRKLYGSPGDIDLWPALMVEDLIPGTRVGPTLM 1216
>gi|20149640 dual oxidase 1 precursor [Homo sapiens]
Length = 1551
Score = 51.6 bits (122), Expect = 2e-06
Identities = 82/351 (23%), Positives = 132/351 (37%), Gaps = 74/351 (21%)
Query: 227 VDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLM----------HYPR 276
+D IYG + LR F G+L + P + P+LM + PR
Sbjct: 173 LDGSAIYGSSHSWSDALRSFSRGQL---ASGPDPAFPRDSQNPLLMWAAPDPATGQNGPR 229
Query: 277 GIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILI 336
G+ A G E P L LW R HN L +HP W DE+LFQ R +I
Sbjct: 230 GL-----YAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVI 284
Query: 337 GETIKIVIEEY--------VQQLSGY--FLQLKFDPELL-FGVQF--------QYRNRIA 377
I + E+ + + +GY FL E + QF Y +
Sbjct: 285 ATYQNIAVYEWLPSFLQKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNAS 344
Query: 378 MEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGR 437
F + + + + + +V + +S E + S+ V+AL+ + QIA R
Sbjct: 345 CHFQGVINRNSSVSRALRVCNSYWSRE----HPSLQSAEDVDALLLGMASQIAER----- 395
Query: 438 NMDHHIL------------------HVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQE 479
+ H+L H+A ++ R++ L + + R G+ P T +Q+
Sbjct: 396 --EDHVLVEDVRDFWPGPLKFSRTDHLA-SCLQRGRDLGLPSYTKARAALGLSPITRWQD 452
Query: 480 L------VGEKEMAAELEELYGDIDALEFYPGLLLEKCH-PNSIFGESMIE 523
+ + + A D+ LE PG LLE P +F ++E
Sbjct: 453 INPALSRSNDTVLEATAALYNQDLSWLELLPGGLLESHRDPGPLFSTIVLE 503
>gi|28872751 dual oxidase 1 precursor [Homo sapiens]
Length = 1551
Score = 51.6 bits (122), Expect = 2e-06
Identities = 82/351 (23%), Positives = 132/351 (37%), Gaps = 74/351 (21%)
Query: 227 VDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLM----------HYPR 276
+D IYG + LR F G+L + P + P+LM + PR
Sbjct: 173 LDGSAIYGSSHSWSDALRSFSRGQL---ASGPDPAFPRDSQNPLLMWAAPDPATGQNGPR 229
Query: 277 GIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILI 336
G+ A G E P L LW R HN L +HP W DE+LFQ R +I
Sbjct: 230 GL-----YAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVI 284
Query: 337 GETIKIVIEEY--------VQQLSGY--FLQLKFDPELL-FGVQF--------QYRNRIA 377
I + E+ + + +GY FL E + QF Y +
Sbjct: 285 ATYQNIAVYEWLPSFLQKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNAS 344
Query: 378 MEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGR 437
F + + + + + +V + +S E + S+ V+AL+ + QIA R
Sbjct: 345 CHFQGVINRNSSVSRALRVCNSYWSRE----HPSLQSAEDVDALLLGMASQIAER----- 395
Query: 438 NMDHHIL------------------HVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQE 479
+ H+L H+A ++ R++ L + + R G+ P T +Q+
Sbjct: 396 --EDHVLVEDVRDFWPGPLKFSRTDHLA-SCLQRGRDLGLPSYTKARAALGLSPITRWQD 452
Query: 480 L------VGEKEMAAELEELYGDIDALEFYPGLLLEKCH-PNSIFGESMIE 523
+ + + A D+ LE PG LLE P +F ++E
Sbjct: 453 INPALSRSNDTVLEATAALYNQDLSWLELLPGGLLESHRDPGPLFSTIVLE 503
>gi|28558982 thyroid peroxidase isoform a [Homo sapiens]
Length = 933
Score = 50.1 bits (118), Expect = 6e-06
Identities = 39/136 (28%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
Query: 227 VDLGHIYGDN--LERQYQLRLFKDGKLKYQVL---DGEMYPPSVE-EAPVLMHYPRGIPP 280
+D +YG + LERQ + +G L+ G Y P V AP GIP
Sbjct: 324 LDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPG 383
Query: 281 QSQ---MAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIG 337
+++ G +P L TLWLREHNR+ LKA + W + ++Q R ++
Sbjct: 384 ETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGA 443
Query: 338 ETIKIVIEEYVQQLSG 353
I + +Y+ ++ G
Sbjct: 444 LHQIITLRDYIPRILG 459
>gi|28558984 thyroid peroxidase isoform b [Homo sapiens]
Length = 876
Score = 50.1 bits (118), Expect = 6e-06
Identities = 39/136 (28%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
Query: 227 VDLGHIYGDN--LERQYQLRLFKDGKLKYQVL---DGEMYPPSVE-EAPVLMHYPRGIPP 280
+D +YG + LERQ + +G L+ G Y P V AP GIP
Sbjct: 324 LDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPG 383
Query: 281 QSQ---MAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIG 337
+++ G +P L TLWLREHNR+ LKA + W + ++Q R ++
Sbjct: 384 ETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGA 443
Query: 338 ETIKIVIEEYVQQLSG 353
I + +Y+ ++ G
Sbjct: 444 LHQIITLRDYIPRILG 459
>gi|28558988 thyroid peroxidase isoform d [Homo sapiens]
Length = 889
Score = 50.1 bits (118), Expect = 6e-06
Identities = 39/136 (28%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
Query: 227 VDLGHIYGDN--LERQYQLRLFKDGKLKYQVL---DGEMYPPSVE-EAPVLMHYPRGIPP 280
+D +YG + LERQ + +G L+ G Y P V AP GIP
Sbjct: 324 LDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPG 383
Query: 281 QSQ---MAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIG 337
+++ G +P L TLWLREHNR+ LKA + W + ++Q R ++
Sbjct: 384 ETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGA 443
Query: 338 ETIKIVIEEYVQQLSG 353
I + +Y+ ++ G
Sbjct: 444 LHQIITLRDYIPRILG 459
>gi|231569458 lactoperoxidase isoform 3 preproprotein [Homo sapiens]
Length = 629
Score = 49.7 bits (117), Expect = 8e-06
Identities = 75/305 (24%), Positives = 120/305 (39%), Gaps = 47/305 (15%)
Query: 302 TLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFD 361
TL+LREHNR+ LK +P W E+L+Q R IL I +Y+ L G +Q
Sbjct: 301 TLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIP 360
Query: 362 PELLFGVQFQYRNRIAMEFNHLYHW-HPLMPDS-FKVGSQ--------EYSYEQFLFNT- 410
P G RI+ F + + H +P S F++ E FNT
Sbjct: 361 P--YQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTW 418
Query: 411 SMLVDYGVEALVDAF----------SRQIAGRIGGGRNMDHHILH---VAVDVIRESREM 457
M+ D G++ LV ++ + G + H +H +A + R+
Sbjct: 419 RMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDH 478
Query: 458 RLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPN 514
+N +R + + +EL + K +A +L LYG D ++ + G +
Sbjct: 479 GQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAI------- 531
Query: 515 SIFGESMIEIGAPFSLKG-LLGNPI----CSPEYW--KPSTFGGEVGFNIVKTATLKKLV 567
E ++E G L LLG +W P F E ++ K + +LV
Sbjct: 532 ---AEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQK-MSFSRLV 587
Query: 568 CLNTK 572
C NT+
Sbjct: 588 CDNTR 592
>gi|40549418 lactoperoxidase isoform 1 preproprotein [Homo sapiens]
Length = 712
Score = 49.7 bits (117), Expect = 8e-06
Identities = 75/305 (24%), Positives = 120/305 (39%), Gaps = 47/305 (15%)
Query: 302 TLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFD 361
TL+LREHNR+ LK +P W E+L+Q R IL I +Y+ L G +Q
Sbjct: 384 TLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIP 443
Query: 362 PELLFGVQFQYRNRIAMEFNHLYHW-HPLMPDS-FKVGSQ--------EYSYEQFLFNT- 410
P G RI+ F + + H +P S F++ E FNT
Sbjct: 444 P--YQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTW 501
Query: 411 SMLVDYGVEALVDAF----------SRQIAGRIGGGRNMDHHILH---VAVDVIRESREM 457
M+ D G++ LV ++ + G + H +H +A + R+
Sbjct: 502 RMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDH 561
Query: 458 RLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAAELEELYGDIDALEFYPGLLLEKCHPN 514
+N +R + + +EL + K +A +L LYG D ++ + G +
Sbjct: 562 GQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAI------- 614
Query: 515 SIFGESMIEIGAPFSLKG-LLGNPI----CSPEYW--KPSTFGGEVGFNIVKTATLKKLV 567
E ++E G L LLG +W P F E ++ K + +LV
Sbjct: 615 ---AEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQK-MSFSRLV 670
Query: 568 CLNTK 572
C NT+
Sbjct: 671 CDNTR 675
>gi|132566532 dual oxidase 2 precursor [Homo sapiens]
Length = 1548
Score = 45.4 bits (106), Expect = 1e-04
Identities = 45/159 (28%), Positives = 62/159 (38%), Gaps = 28/159 (17%)
Query: 227 VDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLM----------HYPR 276
+D IYG + LR F G+L + P + P+LM + PR
Sbjct: 179 LDGSAIYGSSHSWSDALRSFSGGQL---ASGPDPAFPRDSQNPLLMWAAPDPATGQNGPR 235
Query: 277 GIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILI 336
G+ A G E P L LW R HN L +HP W DE+LFQ R +I
Sbjct: 236 GL-----YAFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVI 290
Query: 337 GETIKIVIEEY--------VQQLSGY--FLQLKFDPELL 365
I + E+ + + +GY FL PE +
Sbjct: 291 ATYQNIAVYEWLPSFLQKTLPEYTGYRPFLDPSISPEFV 329
>gi|14211536 neurexin 2 isoform alpha-1 precursor [Homo sapiens]
Length = 1712
Score = 45.4 bits (106), Expect = 1e-04
Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 10/63 (15%)
Query: 19 LPVLLADP---------GAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCT 69
LP L+AD G P C C +QG+C++ D + CDCT T Y GP C
Sbjct: 1075 LPDLIADALHRIGQVERGCDGPSTTCTEESCANQGVCLQ-QWDGFTCDCTMTSYGGPVCN 1133
Query: 70 IPG 72
PG
Sbjct: 1134 DPG 1136
Score = 36.2 bits (82), Expect = 0.088
Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 1/34 (2%)
Query: 35 CCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
C PC++ G+C R G +R+ CDC TG+ G C
Sbjct: 694 CASAPCRNGGVC-REGWNRFICDCIGTGFLGRVC 726
Score = 33.1 bits (74), Expect = 0.75
Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 4/54 (7%)
Query: 20 PVLLADPGAP-TPVNPCCY---YPCQHQGICVRFGLDRYQCDCTRTGYSGPNCT 69
P LL G +P C PC + G+C CDC+ TG+ G C+
Sbjct: 189 PALLGSQGLRGATADPLCAPARNPCANGGLCTVLAPGEVGCDCSHTGFGGKFCS 242
>gi|21166380 neurexin 2 isoform alpha-2 precursor [Homo sapiens]
Length = 1642
Score = 45.4 bits (106), Expect = 1e-04
Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 10/63 (15%)
Query: 19 LPVLLADP---------GAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCT 69
LP L+AD G P C C +QG+C++ D + CDCT T Y GP C
Sbjct: 1035 LPDLIADALHRIGQVERGCDGPSTTCTEESCANQGVCLQ-QWDGFTCDCTMTSYGGPVCN 1093
Query: 70 IPG 72
PG
Sbjct: 1094 DPG 1096
Score = 36.2 bits (82), Expect = 0.088
Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 1/34 (2%)
Query: 35 CCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
C PC++ G+C R G +R+ CDC TG+ G C
Sbjct: 663 CASAPCRNGGVC-REGWNRFICDCIGTGFLGRVC 695
Score = 33.1 bits (74), Expect = 0.75
Identities = 17/54 (31%), Positives = 23/54 (42%), Gaps = 4/54 (7%)
Query: 20 PVLLADPGAP-TPVNPCCY---YPCQHQGICVRFGLDRYQCDCTRTGYSGPNCT 69
P LL G +P C PC + G+C CDC+ TG+ G C+
Sbjct: 189 PALLGSQGLRGATADPLCAPARNPCANGGLCTVLAPGEVGCDCSHTGFGGKFCS 242
>gi|4557759 myeloperoxidase [Homo sapiens]
Length = 745
Score = 44.3 bits (103), Expect = 3e-04
Identities = 55/239 (23%), Positives = 111/239 (46%), Gaps = 29/239 (12%)
Query: 294 LPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIV-IEEYVQQLS 352
+P L TL LREHNR+ LK+ +P W E+L+Q R I +G ++I+ +Y+ +
Sbjct: 409 MPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKI-VGAMVQIITYRDYLPLVL 467
Query: 353 GYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHW-HPLM-PDSFKVGSQEYSYEQ----- 405
G K+ P RIA F + + + H L+ P F++ ++ E
Sbjct: 468 GPTAMRKYLPTYR-SYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVP 526
Query: 406 ----FLFNTSMLVDYGVEALVDA-------FSRQIAGRIGGGR-NMDHHILHVAVDV--- 450
F + ++++ G++ ++ +RQ + R + ++ + +D+
Sbjct: 527 LSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPAL 586
Query: 451 -IRESREMRLQPFNEYRKRFGM-KPYTSFQ--ELVGEKEMAAELEELYGDIDALEFYPG 505
++ SR+ L +N +R+ G+ +P T Q ++ ++A +L E YG + ++ + G
Sbjct: 587 NMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMG 645
>gi|208609951 neurexin 1 isoform alpha2 precursor [Homo sapiens]
Length = 1547
Score = 44.3 bits (103), Expect = 3e-04
Identities = 18/35 (51%), Positives = 24/35 (68%), Gaps = 1/35 (2%)
Query: 34 PCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
PC PC++ G+C R G +RY CDC+ TGY G +C
Sbjct: 719 PCLSNPCKNNGMC-RDGWNRYVCDCSGTGYLGRSC 752
Score = 42.4 bits (98), Expect = 0.001
Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Query: 27 GAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPG 72
G P C C +QG+C++ D + CDC+ T +SGP C PG
Sbjct: 1119 GCEGPSTTCQEDSCSNQGVCLQ-QWDGFSCDCSMTSFSGPLCNDPG 1163
Score = 31.2 bits (69), Expect = 2.8
Identities = 12/31 (38%), Positives = 20/31 (64%), Gaps = 5/31 (16%)
Query: 44 GICVRFGL-----DRYQCDCTRTGYSGPNCT 69
G+C+ G+ D+ CDC+RTG+ G +C+
Sbjct: 226 GVCLNGGVCSVVDDQAVCDCSRTGFRGKDCS 256
>gi|14149613 neurexin 1 isoform alpha1 precursor [Homo sapiens]
Length = 1477
Score = 44.3 bits (103), Expect = 3e-04
Identities = 18/35 (51%), Positives = 24/35 (68%), Gaps = 1/35 (2%)
Query: 34 PCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
PC PC++ G+C R G +RY CDC+ TGY G +C
Sbjct: 679 PCLSNPCKNNGMC-RDGWNRYVCDCSGTGYLGRSC 712
Score = 42.4 bits (98), Expect = 0.001
Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Query: 27 GAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPG 72
G P C C +QG+C++ D + CDC+ T +SGP C PG
Sbjct: 1079 GCEGPSTTCQEDSCSNQGVCLQ-QWDGFSCDCSMTSFSGPLCNDPG 1123
Score = 31.2 bits (69), Expect = 2.8
Identities = 12/31 (38%), Positives = 20/31 (64%), Gaps = 5/31 (16%)
Query: 44 GICVRFGL-----DRYQCDCTRTGYSGPNCT 69
G+C+ G+ D+ CDC+RTG+ G +C+
Sbjct: 226 GVCLNGGVCSVVDDQAVCDCSRTGFRGKDCS 256
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 43.1 bits (100), Expect = 7e-04
Identities = 18/34 (52%), Positives = 21/34 (61%), Gaps = 1/34 (2%)
Query: 37 YYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
+ PC + G C G D+YQC C GYSGPNC I
Sbjct: 303 HQPCLNGGTCSNTGPDKYQCSCPE-GYSGPNCEI 335
Score = 36.6 bits (83), Expect = 0.068
Identities = 16/38 (42%), Positives = 24/38 (63%), Gaps = 2/38 (5%)
Query: 33 NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
N C +PC + G CV G + Y+C+C G++GP+C I
Sbjct: 784 NDCSPHPCYNSGTCVD-GDNWYRCECA-PGFAGPDCRI 819
Score = 31.2 bits (69), Expect = 2.8
Identities = 14/39 (35%), Positives = 21/39 (53%), Gaps = 2/39 (5%)
Query: 30 TPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
T +N C PC + G C R ++ + CDC + G+ G C
Sbjct: 666 TNINDCSQNPCHNGGTC-RDLVNDFYCDC-KNGWKGKTC 702
Score = 30.0 bits (66), Expect = 6.3
Identities = 13/37 (35%), Positives = 22/37 (59%), Gaps = 2/37 (5%)
Query: 32 VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
+N C PC++ G C+ G++ Y+C C+ G+ G C
Sbjct: 630 INDCESNPCRNGGTCID-GVNSYKCICS-DGWEGAYC 664
>gi|41327708 crumbs homolog 1 precursor [Homo sapiens]
Length = 1406
Score = 42.4 bits (98), Expect = 0.001
Identities = 18/43 (41%), Positives = 27/43 (62%), Gaps = 3/43 (6%)
Query: 35 CCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC--TIPGLWT 75
C PC H G+CV G +RY C+CT +G++G +C +P W+
Sbjct: 266 CASQPCLHGGLCVD-GENRYSCNCTGSGFTGTHCETLMPLCWS 307
Score = 30.4 bits (67), Expect = 4.9
Identities = 16/43 (37%), Positives = 20/43 (46%), Gaps = 6/43 (13%)
Query: 32 VNPCCYYPCQHQGICVRFGLDRYQCDC-----TRTGYSGPNCT 69
VN C PCQ+ G C Y C C +RT Y G +C+
Sbjct: 398 VNECSSNPCQNGGTCENLP-GNYTCHCPFDNLSRTFYGGRDCS 439
>gi|21070969 neurexin 3 isoform 1 precursor [Homo sapiens]
Length = 1061
Score = 41.2 bits (95), Expect = 0.003
Identities = 24/70 (34%), Positives = 32/70 (45%), Gaps = 14/70 (20%)
Query: 27 GAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPG------------LW 74
G P C C +QG+C++ + + CDC+ T YSG C PG L+
Sbjct: 672 GCEGPSTTCQEDSCANQGVCMQ-QWEGFTCDCSMTSYSGNQCNDPGATYIFGKSGGLILY 730
Query: 75 TWLRNSLRPS 84
TW N RPS
Sbjct: 731 TWPAND-RPS 739
Score = 40.4 bits (93), Expect = 0.005
Identities = 16/34 (47%), Positives = 22/34 (64%), Gaps = 1/34 (2%)
Query: 35 CCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
C YPC++ +C + G +R+ CDCT TGY G C
Sbjct: 274 CDSYPCKNNAVC-KDGWNRFICDCTGTGYWGRTC 306
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 39.7 bits (91), Expect = 0.008
Identities = 18/37 (48%), Positives = 22/37 (59%), Gaps = 2/37 (5%)
Query: 32 VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
V+PC PCQH G C R + Y C+C GY+G NC
Sbjct: 1085 VDPCLAQPCQHGGTC-RGYMGGYMCECL-PGYNGDNC 1119
Score = 37.7 bits (86), Expect = 0.030
Identities = 17/42 (40%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 33 NPCCYYPCQHQGIC---VRFGLDRYQCDCTRTGYSGPNCTIP 71
+PC PC +G+C V G R+ C C R G+ GP+C++P
Sbjct: 80 DPCHSGPCAGRGVCQSSVVAGTARFSCRCPR-GFRGPDCSLP 120
Score = 35.8 bits (81), Expect = 0.12
Identities = 17/51 (33%), Positives = 22/51 (43%), Gaps = 1/51 (1%)
Query: 20 PVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
P P P PC PC++ G C + G Y C C G+ G NC +
Sbjct: 186 PAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACL-PGFEGQNCEV 235
Score = 33.9 bits (76), Expect = 0.44
Identities = 23/60 (38%), Positives = 29/60 (48%), Gaps = 10/60 (16%)
Query: 12 FLLLLPP--LPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCT 69
F L PP LP L P +PC + PC H GIC ++C C G+SGP C+
Sbjct: 679 FRCLCPPGSLPPLCLPPS-----HPCAHEPCSH-GICYD-APGGFRCVC-EPGWSGPRCS 730
Score = 32.7 bits (73), Expect = 0.98
Identities = 15/39 (38%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
Query: 32 VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
V+ C PC+H G C+ +D+Y C C +G +G NC +
Sbjct: 583 VDECRSQPCRHGGKCLDL-VDKYLCRCP-SGTTGVNCEV 619
Score = 30.4 bits (67), Expect = 4.9
Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 4/46 (8%)
Query: 26 PGAPTPVNPCCYYPCQHQGICV-RFGLDRYQCDCTRTGYSGPNCTI 70
P T VN C PC++Q C+ R G ++ C C G++G C +
Sbjct: 426 PRCETDVNECLSGPCRNQATCLDRIG--QFTCIC-MAGFTGTYCEV 468
Score = 30.4 bits (67), Expect = 4.9
Identities = 16/39 (41%), Positives = 19/39 (48%), Gaps = 2/39 (5%)
Query: 32 VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
V+ C PCQH G C+ + RY C C G G C I
Sbjct: 1123 VDECASQPCQHGGSCIDL-VARYLCSCP-PGTLGVLCEI 1159
Score = 30.0 bits (66), Expect = 6.3
Identities = 13/37 (35%), Positives = 18/37 (48%), Gaps = 1/37 (2%)
Query: 32 VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
++PC PC+H G C C C + G+ GP C
Sbjct: 772 LSPCTPNPCEHGGRCESAPGQLPVCSCPQ-GWQGPRC 807
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 39.7 bits (91), Expect = 0.008
Identities = 17/37 (45%), Positives = 23/37 (62%), Gaps = 2/37 (5%)
Query: 32 VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
+N C +PC ++G CV GL Y+C C GY+G NC
Sbjct: 1026 INECSSHPCLNEGTCVD-GLGTYRCSCP-LGYTGKNC 1060
Score = 34.3 bits (77), Expect = 0.34
Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
Query: 32 VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
++ C PCQH C F + Y+C+C GY G NC
Sbjct: 1150 LDECASNPCQHGATCSDF-IGGYRCECV-PGYQGVNC 1184
Score = 32.3 bits (72), Expect = 1.3
Identities = 13/30 (43%), Positives = 18/30 (60%), Gaps = 2/30 (6%)
Query: 39 PCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
PC+H G CV + C+C + GY+GP C
Sbjct: 426 PCEHAGKCVNTD-GAFHCECLK-GYAGPRC 453
Score = 32.3 bits (72), Expect = 1.3
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
Query: 32 VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
+N C PC + G CV ++R+QC C G++GP C I
Sbjct: 495 INECQSNPCVNNGQCVD-KVNRFQCLCP-PGFTGPVCQI 531
Score = 32.3 bits (72), Expect = 1.3
Identities = 16/44 (36%), Positives = 26/44 (59%), Gaps = 2/44 (4%)
Query: 30 TPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGL 73
T VN C PC+++G CV+ + QC C +G++G C +P +
Sbjct: 1062 TLVNLCSRSPCKNKGTCVQKKAES-QCLCP-SGWAGAYCDVPNV 1103
Score = 32.0 bits (71), Expect = 1.7
Identities = 14/38 (36%), Positives = 21/38 (55%), Gaps = 2/38 (5%)
Query: 33 NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
N C PCQ+ G C ++ Y+C C + G+ G NC +
Sbjct: 759 NECLSNPCQNGGTCDNL-VNGYRCTC-KKGFKGYNCQV 794
Score = 30.8 bits (68), Expect = 3.7
Identities = 13/29 (44%), Positives = 16/29 (55%), Gaps = 2/29 (6%)
Query: 40 CQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
CQH G+C+ G Y C C GY+G C
Sbjct: 1120 CQHSGVCINAGNTHY-CQCP-LGYTGSYC 1146
Score = 30.4 bits (67), Expect = 4.9
Identities = 13/39 (33%), Positives = 22/39 (56%), Gaps = 2/39 (5%)
Query: 30 TPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
T +N C PC++ G C + ++ Y C C + G+ G +C
Sbjct: 948 TDMNECLSEPCKNGGTCSDY-VNSYTCKC-QAGFDGVHC 984
Score = 29.6 bits (65), Expect = 8.3
Identities = 11/30 (36%), Positives = 16/30 (53%), Gaps = 1/30 (3%)
Query: 39 PCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
PC + G C D Y+C C + G++G C
Sbjct: 114 PCLNGGTCHMLSRDTYECTC-QVGFTGKEC 142
Score = 29.6 bits (65), Expect = 8.3
Identities = 12/35 (34%), Positives = 18/35 (51%), Gaps = 1/35 (2%)
Query: 34 PCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
PC PC + G C + G ++C+C G+ G C
Sbjct: 224 PCAPSPCVNGGTCRQTGDFTFECNCL-PGFEGSTC 257
Score = 29.6 bits (65), Expect = 8.3
Identities = 14/42 (33%), Positives = 20/42 (47%), Gaps = 2/42 (4%)
Query: 30 TPVNPCCYYPCQHQGICVRF-GLDRYQCDCTRTGYSGPNCTI 70
T + PC PC++ +C + Y C C G+ G CTI
Sbjct: 832 TVLAPCSPNPCENAAVCKESPNFESYTCLCA-PGWQGQRCTI 872
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 39.3 bits (90), Expect = 0.010
Identities = 18/37 (48%), Positives = 22/37 (59%), Gaps = 2/37 (5%)
Query: 32 VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
VN C PC H G C + G Y+C C + GY+GPNC
Sbjct: 1022 VNECDSQPCLHGGTC-QDGCGSYRCTCPQ-GYTGPNC 1056
Score = 38.9 bits (89), Expect = 0.014
Identities = 22/46 (47%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
Query: 25 DPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
DP + VN C PC H G C R L+ Y+CDC G+SG NC I
Sbjct: 710 DPTCLSEVNECNSNPCVH-GAC-RDSLNGYKCDCD-PGWSGTNCDI 752
Score = 37.0 bits (84), Expect = 0.052
Identities = 18/42 (42%), Positives = 22/42 (52%), Gaps = 4/42 (9%)
Query: 33 NPCCYYPCQHQGIC---VRFGLDRYQCDCTRTGYSGPNCTIP 71
NPC PC++ G C R G+ Y C C G+SGP C P
Sbjct: 61 NPCLSTPCKNAGTCHVVDRRGVADYACSCA-LGFSGPLCLTP 101
Score = 35.0 bits (79), Expect = 0.20
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 26 PGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
P P PC PCQ+ G C G ++C C G++G NC
Sbjct: 213 PNCERPYVPCSPSPCQNGGTCRPTGDVTHECACL-PGFTGQNC 254
Score = 34.7 bits (78), Expect = 0.26
Identities = 17/41 (41%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
Query: 30 TPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
T +N C PC+H G C + + Y C C + G +GPNC I
Sbjct: 602 TNINECSSQPCRHGGTC-QDRDNAYLCFCLK-GTTGPNCEI 640
Score = 33.9 bits (76), Expect = 0.44
Identities = 15/45 (33%), Positives = 23/45 (51%), Gaps = 2/45 (4%)
Query: 26 PGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
P T +N C PC +QG C+ + Y+C+C Y+G C +
Sbjct: 786 PNCQTNINECASNPCLNQGTCID-DVAGYKCNCL-LPYTGATCEV 828
Score = 32.7 bits (73), Expect = 0.98
Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 2/40 (5%)
Query: 30 TPV-NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
TP+ N C PC++ G C L Y+C C G+SG +C
Sbjct: 100 TPLDNACLTNPCRNGGTCDLLTLTEYKCRCP-PGWSGKSC 138
Score = 32.3 bits (72), Expect = 1.3
Identities = 15/37 (40%), Positives = 19/37 (51%), Gaps = 2/37 (5%)
Query: 32 VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
+N C PC+H C Y+C C + GYSG NC
Sbjct: 870 INECVLSPCRHGASCQNTH-GGYRCHC-QAGYSGRNC 904
Score = 31.2 bits (69), Expect = 2.8
Identities = 15/45 (33%), Positives = 21/45 (46%), Gaps = 2/45 (4%)
Query: 26 PGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
P VN C PCQ+ C+ + +QC C GY G +C +
Sbjct: 447 PRCEIDVNECVSNPCQNDATCLD-QIGEFQCIC-MPGYEGVHCEV 489
Score = 31.2 bits (69), Expect = 2.8
Identities = 16/36 (44%), Positives = 18/36 (50%), Gaps = 2/36 (5%)
Query: 33 NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
N C PC + G C Y C C R G+SGPNC
Sbjct: 755 NECESNPCVNGGTCKDM-TSGYVCTC-REGFSGPNC 788
Score = 31.2 bits (69), Expect = 2.8
Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 2/39 (5%)
Query: 32 VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
++ C +PCQ+ G C+ + Y+C C R G G +C I
Sbjct: 1184 IDECLSHPCQNGGTCLDLP-NTYKCSCPR-GTQGVHCEI 1220
>gi|110735443 delta-like 1 [Homo sapiens]
Length = 723
Score = 38.9 bits (89), Expect = 0.014
Identities = 18/38 (47%), Positives = 22/38 (57%), Gaps = 2/38 (5%)
Query: 31 PVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
PV+ C + PC + C G RY C+C R GY GPNC
Sbjct: 481 PVSRCEHAPCHNGATCHERG-HRYVCECAR-GYGGPNC 516
Score = 32.7 bits (73), Expect = 0.98
Identities = 14/40 (35%), Positives = 21/40 (52%), Gaps = 2/40 (5%)
Query: 32 VNPCCYY-PCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
+N C ++ PC++ C G Y C C R GY+G C +
Sbjct: 289 LNYCTHHKPCKNGATCTNTGQGSYTCSC-RPGYTGATCEL 327
>gi|4503595 eosinophil peroxidase [Homo sapiens]
Length = 715
Score = 38.5 bits (88), Expect = 0.018
Identities = 53/257 (20%), Positives = 106/257 (41%), Gaps = 41/257 (15%)
Query: 295 PGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGY 354
P L TL++REHNR+ L+ +P W ++L+ R I+ G ++I+
Sbjct: 382 PKLAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIM-GAMVQIITYR-------D 433
Query: 355 FLQLKFDPELLFGVQFQYRN-------RIAMEFNHLYHW--HPLMPDSFKVGSQEYS--- 402
FL L YR R+A F + + L P F++ SQ +
Sbjct: 434 FLPLVLGKARARRTLGHYRGYCSNVDPRVANVFTLAFRFGHTMLQPFMFRLDSQYRASAP 493
Query: 403 ------YEQFLFNTSMLVDYGVEALVDA-------FSRQIAGRIGGGRN-MDHHILHVAV 448
F + ++ + G++ ++ +RQ A + R+ + + + +
Sbjct: 494 NSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDELRDRLFRQVRRIGL 553
Query: 449 DV----IRESREMRLQPFNEYRKRFGMKPYTSFQEL---VGEKEMAAELEELYGDIDALE 501
D+ ++ SR+ L +N +R+ G+ + +L + +++A + LYG D ++
Sbjct: 554 DLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLNLYGTPDNID 613
Query: 502 FYPGLLLEKCHPNSIFG 518
+ G + E P + G
Sbjct: 614 IWIGAIAEPLLPGARVG 630
>gi|38348304 von Willebrand factor A domain containing 2 [Homo
sapiens]
Length = 725
Score = 38.5 bits (88), Expect = 0.018
Identities = 17/37 (45%), Positives = 19/37 (51%)
Query: 34 PCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
PC PCQ+ G CV GLD YQC C NC +
Sbjct: 298 PCDSQPCQNGGTCVPEGLDGYQCLCPLAFGGEANCAL 334
>gi|4759146 slit homolog 2 [Homo sapiens]
Length = 1529
Score = 38.1 bits (87), Expect = 0.023
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 33 NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIP 71
NPC PC++ G C +D Y+C C G+ G +C +P
Sbjct: 920 NPCLSNPCKNDGTCNSDPVDFYRCTCP-YGFKGQDCDVP 957
Score = 30.8 bits (68), Expect = 3.7
Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 3/42 (7%)
Query: 31 PVNPCCYYPCQHQGIC-VRFG-LDRYQCDCTRTGYSGPNCTI 70
P++ C PC+H G C ++ G D + C C G+ G NC +
Sbjct: 957 PIHACISNPCKHGGTCHLKEGEEDGFWCICA-DGFEGENCEV 997
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 37.7 bits (86), Expect = 0.030
Identities = 14/37 (37%), Positives = 24/37 (64%), Gaps = 2/37 (5%)
Query: 32 VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
++ C PC H G+C+ G++ Y CDC ++G+ G +C
Sbjct: 1005 LDECLSEPCLHDGVCID-GINHYTCDC-KSGFFGTHC 1039
Score = 32.3 bits (72), Expect = 1.3
Identities = 15/37 (40%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
Query: 33 NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCT 69
+PC C + G C+ G Y C+CT TG+ G CT
Sbjct: 2612 SPCSLMKCGNGGTCIESGTSVY-CNCT-TGWKGSFCT 2646
Score = 31.2 bits (69), Expect = 2.8
Identities = 14/39 (35%), Positives = 21/39 (53%), Gaps = 2/39 (5%)
Query: 32 VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTI 70
+N C PC++ G CV +R+ C+C Y GP C +
Sbjct: 929 INECSSEPCKNNGTCVDL-TNRFFCNC-EPEYHGPFCEL 965
Score = 30.0 bits (66), Expect = 6.3
Identities = 13/37 (35%), Positives = 19/37 (51%), Gaps = 2/37 (5%)
Query: 32 VNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNC 68
+N C PC ++G C + + C C R GY+G C
Sbjct: 1080 INDCTSIPCMNEGFCQK-SAHGFTCICPR-GYTGAYC 1114
>gi|11321571 slit homolog 3 [Homo sapiens]
Length = 1523
Score = 37.4 bits (85), Expect = 0.040
Identities = 14/39 (35%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Query: 33 NPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIP 71
N C PC++ G C + ++ Y+C C + Y G +CT+P
Sbjct: 918 NACLSSPCKNNGTCTQDPVELYRCACPYS-YKGKDCTVP 955
Score = 33.5 bits (75), Expect = 0.57
Identities = 16/42 (38%), Positives = 19/42 (45%), Gaps = 3/42 (7%)
Query: 31 PVNPCCYYPCQHQGIC--VRFGLDRYQCDCTRTGYSGPNCTI 70
P+N C PCQH G C D + C C G+ G C I
Sbjct: 955 PINTCIQNPCQHGGTCHLSDSHKDGFSCSCP-LGFEGQRCEI 995
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.324 0.142 0.454
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,469,713
Number of Sequences: 37866
Number of extensions: 1240800
Number of successful extensions: 3010
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 62
Number of HSP's that attempted gapping in prelim test: 2828
Number of HSP's gapped (non-prelim): 232
length of query: 599
length of database: 18,247,518
effective HSP length: 108
effective length of query: 491
effective length of database: 14,157,990
effective search space: 6951573090
effective search space used: 6951573090
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.