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Search of human proteins with 17999524
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|17999524 proacrosin binding protein sp32 precursor [Homo
sapiens]
(543 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|17999524 proacrosin binding protein sp32 precursor [Homo sapi... 1118 0.0
gi|17975763 myelin transcription factor 1 [Homo sapiens] 52 1e-06
gi|110347429 mediator complex subunit 12 [Homo sapiens] 50 7e-06
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 49 1e-05
gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo ... 49 2e-05
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 47 3e-05
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] 47 3e-05
gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sap... 47 4e-05
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 47 6e-05
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 47 6e-05
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 46 8e-05
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 46 8e-05
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 46 8e-05
gi|21735415 centromere protein B [Homo sapiens] 46 8e-05
gi|215490093 ATPase, (Na+)/K+ transporting, beta 4 polypeptide i... 46 8e-05
gi|6912256 ATPase, (Na+)/K+ transporting, beta 4 polypeptide iso... 46 8e-05
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] 46 1e-04
gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ... 45 1e-04
gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo ... 45 1e-04
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 45 1e-04
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 45 1e-04
gi|221219020 NYD-SP11 protein [Homo sapiens] 45 2e-04
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 45 2e-04
gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Hom... 45 2e-04
gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Hom... 45 2e-04
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 45 2e-04
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 45 2e-04
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 45 2e-04
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 44 3e-04
gi|4503257 death-domain associated protein isoform a [Homo sapiens] 44 3e-04
>gi|17999524 proacrosin binding protein sp32 precursor [Homo
sapiens]
Length = 543
Score = 1118 bits (2893), Expect = 0.0
Identities = 543/543 (100%), Positives = 543/543 (100%)
Query: 1 MRKPAAGFLPSLLKVLLLPLAPAAAQDSTQASTPGSPLSPTEYERFFALLTPTWKAETTC 60
MRKPAAGFLPSLLKVLLLPLAPAAAQDSTQASTPGSPLSPTEYERFFALLTPTWKAETTC
Sbjct: 1 MRKPAAGFLPSLLKVLLLPLAPAAAQDSTQASTPGSPLSPTEYERFFALLTPTWKAETTC 60
Query: 61 RLRATHGCRNPTLVQLDQYENHGLVPDGAVCSNLPYASWFESFCQFTHYRCSNHVYYAKR 120
RLRATHGCRNPTLVQLDQYENHGLVPDGAVCSNLPYASWFESFCQFTHYRCSNHVYYAKR
Sbjct: 61 RLRATHGCRNPTLVQLDQYENHGLVPDGAVCSNLPYASWFESFCQFTHYRCSNHVYYAKR 120
Query: 121 VLCSQPVSILSPNTLKEIEASAEVSPTTMTSPISPHFTVTERQTFQPWPERLSNNVEELL 180
VLCSQPVSILSPNTLKEIEASAEVSPTTMTSPISPHFTVTERQTFQPWPERLSNNVEELL
Sbjct: 121 VLCSQPVSILSPNTLKEIEASAEVSPTTMTSPISPHFTVTERQTFQPWPERLSNNVEELL 180
Query: 181 QSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKE 240
QSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKE
Sbjct: 181 QSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKE 240
Query: 241 GREAVSQLQTDSEPKFHSESLSSNPSSFAPRVREVESTPMIMENIQELIRSAQEIDEMNE 300
GREAVSQLQTDSEPKFHSESLSSNPSSFAPRVREVESTPMIMENIQELIRSAQEIDEMNE
Sbjct: 241 GREAVSQLQTDSEPKFHSESLSSNPSSFAPRVREVESTPMIMENIQELIRSAQEIDEMNE 300
Query: 301 IYDENSYWRNQNPGSLLQLPHTEALLVLCYSIVENTCIITPTAKAWKYMEEEILGFGKSV 360
IYDENSYWRNQNPGSLLQLPHTEALLVLCYSIVENTCIITPTAKAWKYMEEEILGFGKSV
Sbjct: 301 IYDENSYWRNQNPGSLLQLPHTEALLVLCYSIVENTCIITPTAKAWKYMEEEILGFGKSV 360
Query: 361 CDSLGRRHMSTCALCDFCSLKLEQCHSEASLQRQQCDTSHKTPFVSPLLASQSLSIGNQV 420
CDSLGRRHMSTCALCDFCSLKLEQCHSEASLQRQQCDTSHKTPFVSPLLASQSLSIGNQV
Sbjct: 361 CDSLGRRHMSTCALCDFCSLKLEQCHSEASLQRQQCDTSHKTPFVSPLLASQSLSIGNQV 420
Query: 421 GSPESGRFYGLDLYGGLHMDFWCARLATKGCEDVRVSGWLQTEFLSFQDGDFPTKICDTD 480
GSPESGRFYGLDLYGGLHMDFWCARLATKGCEDVRVSGWLQTEFLSFQDGDFPTKICDTD
Sbjct: 421 GSPESGRFYGLDLYGGLHMDFWCARLATKGCEDVRVSGWLQTEFLSFQDGDFPTKICDTD 480
Query: 481 YIQYPNYCSFKSQQCLMRNRNRKVSRMRCLQNETYSALSPGKSEDVVLRWSQEFSTLTLG 540
YIQYPNYCSFKSQQCLMRNRNRKVSRMRCLQNETYSALSPGKSEDVVLRWSQEFSTLTLG
Sbjct: 481 YIQYPNYCSFKSQQCLMRNRNRKVSRMRCLQNETYSALSPGKSEDVVLRWSQEFSTLTLG 540
Query: 541 QFG 543
QFG
Sbjct: 541 QFG 543
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 52.4 bits (124), Expect = 1e-06
Identities = 34/122 (27%), Positives = 60/122 (49%), Gaps = 1/122 (0%)
Query: 177 EELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQ 236
++L SL E++ + K E E +E ++EE + +EE+EEE+EEE ++EE +
Sbjct: 233 QDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEE 292
Query: 237 GTKEGREAVSQLQTDSEPKFHSESLSSNPSSFAPRVREVES-TPMIMENIQELIRSAQEI 295
+E E + + + E S + AP +R ES +P ++ +RS +
Sbjct: 293 EEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDK 352
Query: 296 DE 297
DE
Sbjct: 353 DE 354
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 49.7 bits (117), Expect = 7e-06
Identities = 47/232 (20%), Positives = 105/232 (45%), Gaps = 40/232 (17%)
Query: 63 RATHGCRNPTLVQLDQYENHGLVPDGAVCSNLP-YASWFESFCQFTHYRCSNHVYYAKRV 121
++TH NPTLV ++ P G V P Y S +F+H
Sbjct: 1974 QSTHPSTNPTLVDPTRHLQQR--PSGYVHQQAPTYGHGLTSTQRFSHQTLQQ-------- 2023
Query: 122 LCSQPVSILSPNTLKEIEASAEVSPTTMTSPISPHFTVTERQTFQPWPERLSNNVEELLQ 181
+ +S ++P + + ++A ++ I P E+Q Q ++ ++ Q
Sbjct: 2024 --TPMISTMTPMSAQGVQAGVR------STAILP-----EQQQQQQQQQQQQQQQQQQQQ 2070
Query: 182 SSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEG 241
Q+Q H ++Q + +Q Q+ +Q++ Q+Q++Q+++Q+++ +Q++ Q ++
Sbjct: 2071 Q------QQQQQYHIRQQ--QQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQ 2122
Query: 242 REAVSQLQTDSEPKFHSESLSSNPSSFAPRVREVESTPMIMENIQELIRSAQ 293
+ A Q Q S+P+F + L + ++ + T ++ +Q+ + + Q
Sbjct: 2123 QAAPPQPQPQSQPQFQRQGLQ--------QTQQQQQTAALVRQLQQQLSNTQ 2166
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 48.9 bits (115), Expect = 1e-05
Identities = 37/128 (28%), Positives = 63/128 (49%), Gaps = 11/128 (8%)
Query: 147 TTMTSPISPHFTVT---ERQTFQ----PWPERLSNNVEE----LLQSSLSLGGQEQAPEH 195
T +P+ P VT +++T + P P R+ V+E LL + + AP
Sbjct: 1275 TPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVS 1334
Query: 196 KQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSEPK 255
E ++ + ++EE +++EE+EEE+EEEG++EEG G E ++ Q EP+
Sbjct: 1335 PNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPE 1394
Query: 256 FHSESLSS 263
+E S
Sbjct: 1395 ISTEKEDS 1402
Score = 41.2 bits (95), Expect = 0.002
Identities = 18/48 (37%), Positives = 32/48 (66%)
Query: 187 GGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEE 234
G + Q E +E E +E +E ++EE +++E++EEE+EEE ++EE
Sbjct: 1056 GERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEE 1103
Score = 40.0 bits (92), Expect = 0.005
Identities = 17/47 (36%), Positives = 34/47 (72%)
Query: 199 QGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAV 245
Q +E +E ++E ++EE +++EE+EEE+EE+ ++EE + +E E +
Sbjct: 1060 QLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENI 1106
Score = 38.5 bits (88), Expect = 0.016
Identities = 15/39 (38%), Positives = 28/39 (71%)
Query: 196 KQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEE 234
K+ E +E +E ++EE ++++E+EEE+EEE ++EE
Sbjct: 1066 KESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEE 1104
Score = 35.8 bits (81), Expect = 0.10
Identities = 17/63 (26%), Positives = 33/63 (52%)
Query: 192 APEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTD 251
+PE + G + + EE +++E++EEE+EEE ++E+ + +E E +
Sbjct: 1048 SPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQ 1107
Query: 252 SEP 254
S P
Sbjct: 1108 SSP 1110
Score = 33.9 bits (76), Expect = 0.39
Identities = 31/147 (21%), Positives = 53/147 (36%), Gaps = 3/147 (2%)
Query: 139 EASAEVSPTTMTSPISPHFTVTERQTFQPWPERLSNNVEELLQSSLSLGGQEQAPEHKQE 198
E A VSP T + + + E EE + G E+ P+ +
Sbjct: 1328 ETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKS 1387
Query: 199 QGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSE--PKF 256
Q E + T++ EE+EEE EE E+ E + + + E P+
Sbjct: 1388 QEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRE 1447
Query: 257 HSESLSSNPSSFAP-RVREVESTPMIM 282
+ + N +F V+ S P ++
Sbjct: 1448 SFKEVLENQETFLDLNVQPGHSNPEVL 1474
Score = 33.5 bits (75), Expect = 0.51
Identities = 14/43 (32%), Positives = 25/43 (58%)
Query: 184 LSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQ 226
L L + E ++E E +E +E +EE +++EE+EEE+
Sbjct: 1062 LELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEE 1104
Score = 31.6 bits (70), Expect = 1.9
Identities = 13/45 (28%), Positives = 28/45 (62%)
Query: 178 ELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQ 222
+LL+ S +E+ E ++E+ E +E +E ++EE +++EE+
Sbjct: 1060 QLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEE 1104
Score = 31.2 bits (69), Expect = 2.5
Identities = 22/115 (19%), Positives = 49/115 (42%), Gaps = 8/115 (6%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQ----EHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREA 244
+E+ E ++E+ E E + K +G K +E+EE + K++ + E
Sbjct: 1353 EEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEE 1412
Query: 245 VSQLQTDSEPKFHSESLSSNPSSFAPRVREVESTPMIMENIQELIRSAQEIDEMN 299
+ D EP + + + + EVE + E+ +E++ + + ++N
Sbjct: 1413 ----EEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLN 1463
>gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo
sapiens]
Length = 142
Score = 48.5 bits (114), Expect = 2e-05
Identities = 29/111 (26%), Positives = 53/111 (47%), Gaps = 3/111 (2%)
Query: 167 PWPERLSNNVEELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQ 226
P+P N+ L S+ S+ + H + + +E ++EE +++E++ EE+
Sbjct: 27 PYPHSKRENLAGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEK 86
Query: 227 EEEGKQEEGQGTKEGREAVSQLQTDSEPKFHSESLSSNPSSFAPRVREVES 277
EGK+ E + KE E + + + E + E +S S A R RE E+
Sbjct: 87 RREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVS---FSLATRERETET 134
Score = 40.0 bits (92), Expect = 0.005
Identities = 23/67 (34%), Positives = 42/67 (62%), Gaps = 3/67 (4%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQL 248
+E+ E K+ + E R+E + K+EE +++EE+EEE+EEE ++EE + A +
Sbjct: 74 EEKRREEKRRE--EKRREGKRREKEEE-KEEEEEEEEEEEEEEEEEEEEEVSFSLATRER 130
Query: 249 QTDSEPK 255
+T++E K
Sbjct: 131 ETETEEK 137
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 47.4 bits (111), Expect = 3e-05
Identities = 38/134 (28%), Positives = 66/134 (49%), Gaps = 3/134 (2%)
Query: 192 APEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTD 251
AP Q G E +E ++ ++EE ++EE+EEE+EEE ++EE + +E AV+ L
Sbjct: 723 APVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVA-LGEV 781
Query: 252 SEPKFHSESLSSNPSSFAPRVREVESTPMIMENIQELIRSAQEIDEMNEIYDENSYWRNQ 311
P+ S S S S+ R +E + ++ ++ +E A D E + +
Sbjct: 782 LGPRSGSSSEGSERST--DRSQEGAPSTLLADDQKESRGRASMADGDLEPEEGSKTLVLV 839
Query: 312 NPGSLLQLPHTEAL 325
+PG + + P T L
Sbjct: 840 SPGDMKKSPVTAEL 853
Score = 42.7 bits (99), Expect = 8e-04
Identities = 19/46 (41%), Positives = 33/46 (71%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEE 234
Q QA ++E+ E +E +E ++EE +++EE+EEE+EEE ++EE
Sbjct: 726 QPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 39.3 bits (90), Expect = 0.009
Identities = 15/41 (36%), Positives = 29/41 (70%)
Query: 188 GQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEE 228
G+E+ E ++++ E E +E ++EE +++EE+EEE+EE
Sbjct: 731 GKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 37.4 bits (85), Expect = 0.035
Identities = 15/41 (36%), Positives = 28/41 (68%)
Query: 187 GGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQE 227
G +E+ E + E+ E +E +E ++EE +++EE+EEE+E
Sbjct: 731 GKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 33.9 bits (76), Expect = 0.39
Identities = 18/64 (28%), Positives = 35/64 (54%), Gaps = 1/64 (1%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAV-SQ 247
+E+ E ++E+ + +E +E ++EE +++EE+EEE E G + G + S+
Sbjct: 735 EEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSE 794
Query: 248 LQTD 251
TD
Sbjct: 795 RSTD 798
Score = 31.6 bits (70), Expect = 1.9
Identities = 16/67 (23%), Positives = 34/67 (50%)
Query: 205 QEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSEPKFHSESLSSN 264
Q P + + K+EE+EEE++EE ++E+ + +E E + + + E + + + +
Sbjct: 719 QVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVAL 778
Query: 265 PSSFAPR 271
PR
Sbjct: 779 GEVLGPR 785
>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
Length = 587
Score = 47.4 bits (111), Expect = 3e-05
Identities = 24/70 (34%), Positives = 41/70 (58%), Gaps = 2/70 (2%)
Query: 170 ERLSNNVEELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEE 229
E+L +E + + + E ++E+G E +E +E +EE +++EE+EEE+EEE
Sbjct: 339 EQLQEVLEGFNMAKVLASLSDDEDEEEEEEGEEEEEEAEEE--EEEDEEEEEEEEEEEEE 396
Query: 230 GKQEEGQGTK 239
Q+ GQG K
Sbjct: 397 EPQQRGQGEK 406
Score = 38.1 bits (87), Expect = 0.021
Identities = 16/38 (42%), Positives = 27/38 (71%)
Query: 210 EHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQ 247
E ++EEG+++EE+ EE+EEE ++EE + +E E Q
Sbjct: 363 EEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQ 400
Score = 33.9 bits (76), Expect = 0.39
Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 10/78 (12%)
Query: 198 EQGVEHRQEPTQEHKQ---------EEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQL 248
E+G E QE + +E +++EE+ EE+EEE ++EE + +E E +
Sbjct: 335 EEGCEQLQEVLEGFNMAKVLASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEE 394
Query: 249 QTDSEPKFHSESLSSNPS 266
+ + + + E S+ PS
Sbjct: 395 EEEPQQRGQGEK-SATPS 411
>gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo
sapiens]
Length = 525
Score = 47.0 bits (110), Expect = 4e-05
Identities = 41/160 (25%), Positives = 71/160 (44%), Gaps = 14/160 (8%)
Query: 135 LKEIEASAEVSPTTMTSPISPHFTVTERQTFQPWPERLSNNVEELLQSSLSLGGQEQAPE 194
L E EA A +S T T S + V W E L + L E
Sbjct: 248 LSEAEAQALLSGDTQTDATSFYDRV--------WAAIRDKYRSEALPTDLPAPSAPDLTE 299
Query: 195 HKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSEP 254
K+EQ PT+E ++EE +++EE EEE+EEE + +G+ K S + D P
Sbjct: 300 PKEEQPPVP-SSPTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPK----PASPAEEDKMP 354
Query: 255 KFHSESLSSNPSSFAPRVREVESTPMIMENIQELIRSAQE 294
+ ++ + ++ R + E +++++E IR+ ++
Sbjct: 355 PYDEQTQAFIDAAQEAR-NKFEEAERSLKDMEESIRNLEQ 393
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 46.6 bits (109), Expect = 6e-05
Identities = 36/165 (21%), Positives = 77/165 (46%), Gaps = 14/165 (8%)
Query: 129 ILSPNTLKEIEASAEVSPTTMTSPISPHFTVTERQTFQPWPERLSNNVEELLQSSLSLGG 188
I+ +++ ++ E + T +T ++ +++ + E EE+ +
Sbjct: 456 IIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPV-- 513
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQL 248
+ APE K+E+G E ++EEGQ++EE+E+E + + EEG KEG S+
Sbjct: 514 KATAPEVKEEEG---------EKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGS---SEK 561
Query: 249 QTDSEPKFHSESLSSNPSSFAPRVREVESTPMIMENIQELIRSAQ 293
+ + + +E+ + + A ++VE + +EL+ A+
Sbjct: 562 EEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAK 606
Score = 34.7 bits (78), Expect = 0.23
Identities = 27/107 (25%), Positives = 50/107 (46%), Gaps = 8/107 (7%)
Query: 188 GQEQAPEH----KQEQGVEHRQEPTQEHKQEEGQKQE---EQEEEQEEEGKQEEGQGTKE 240
GQE+ E K +Q E E ++EEG+++E E E E EE +EE + ++
Sbjct: 532 GQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEK 591
Query: 241 GREAVSQLQTDSEPKFHSESLSSNPSSFAPRVREVESTPMIMENIQE 287
E ++ + ++ K + +P +P V E +P+ ++E
Sbjct: 592 SEEVATKEELVADAKVEKPEKAKSPVPKSP-VEEKGKSPVPKSPVEE 637
Score = 32.3 bits (72), Expect = 1.1
Identities = 25/96 (26%), Positives = 47/96 (48%), Gaps = 10/96 (10%)
Query: 139 EASAEVSPTTMTSPISPHFTVTERQTFQPWPERLSNNVEELLQSSLSLGGQEQAPEHKQE 198
EA AEV T+T + H ++ +P + E+ + + GG E+ K
Sbjct: 741 EAVAEV--VTITKSVKVHLEKETKEEGKPLQQ------EKEKEKAGGEGGSEEEGSDKGA 792
Query: 199 QGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEE 234
+G R+E + + EG+++ EQE +++ G++EE
Sbjct: 793 KG--SRKEDIAVNGEVEGKEEVEQETKEKGSGREEE 826
Score = 30.8 bits (68), Expect = 3.3
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 191 QAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKE---GRE 243
Q + K++ G E E K +G ++E+ E EGK+E Q TKE GRE
Sbjct: 769 QQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGRE 824
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 46.6 bits (109), Expect = 6e-05
Identities = 36/165 (21%), Positives = 77/165 (46%), Gaps = 14/165 (8%)
Query: 129 ILSPNTLKEIEASAEVSPTTMTSPISPHFTVTERQTFQPWPERLSNNVEELLQSSLSLGG 188
I+ +++ ++ E + T +T ++ +++ + E EE+ +
Sbjct: 80 IIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPV-- 137
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQL 248
+ APE K+E+G E ++EEGQ++EE+E+E + + EEG KEG S+
Sbjct: 138 KATAPEVKEEEG---------EKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGS---SEK 185
Query: 249 QTDSEPKFHSESLSSNPSSFAPRVREVESTPMIMENIQELIRSAQ 293
+ + + +E+ + + A ++VE + +EL+ A+
Sbjct: 186 EEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAK 230
Score = 34.7 bits (78), Expect = 0.23
Identities = 27/107 (25%), Positives = 50/107 (46%), Gaps = 8/107 (7%)
Query: 188 GQEQAPEH----KQEQGVEHRQEPTQEHKQEEGQKQE---EQEEEQEEEGKQEEGQGTKE 240
GQE+ E K +Q E E ++EEG+++E E E E EE +EE + ++
Sbjct: 156 GQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEK 215
Query: 241 GREAVSQLQTDSEPKFHSESLSSNPSSFAPRVREVESTPMIMENIQE 287
E ++ + ++ K + +P +P V E +P+ ++E
Sbjct: 216 SEEVATKEELVADAKVEKPEKAKSPVPKSP-VEEKGKSPVPKSPVEE 261
Score = 32.3 bits (72), Expect = 1.1
Identities = 25/96 (26%), Positives = 47/96 (48%), Gaps = 10/96 (10%)
Query: 139 EASAEVSPTTMTSPISPHFTVTERQTFQPWPERLSNNVEELLQSSLSLGGQEQAPEHKQE 198
EA AEV T+T + H ++ +P + E+ + + GG E+ K
Sbjct: 365 EAVAEV--VTITKSVKVHLEKETKEEGKPLQQ------EKEKEKAGGEGGSEEEGSDKGA 416
Query: 199 QGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEE 234
+G R+E + + EG+++ EQE +++ G++EE
Sbjct: 417 KG--SRKEDIAVNGEVEGKEEVEQETKEKGSGREEE 450
Score = 30.8 bits (68), Expect = 3.3
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 191 QAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKE---GRE 243
Q + K++ G E E K +G ++E+ E EGK+E Q TKE GRE
Sbjct: 393 QQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGRE 448
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 46.2 bits (108), Expect = 8e-05
Identities = 27/115 (23%), Positives = 62/115 (53%), Gaps = 5/115 (4%)
Query: 129 ILSPNTLKEIEASAEVSPTTMTSPISPHFTVTERQTFQPWPERLSNNVEELLQSSLSLGG 188
+++P +++I +SP + + + V +Q Q E E+L L L
Sbjct: 98 VITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQ--QQLQEFYKKQQEQL---HLQLLQ 152
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGRE 243
Q+Q + +Q+Q + +Q+ Q+ +Q++ Q+Q++Q+++Q+ GKQ + Q ++ ++
Sbjct: 153 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 207
Score = 39.7 bits (91), Expect = 0.007
Identities = 14/58 (24%), Positives = 38/58 (65%)
Query: 196 KQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSE 253
+Q+Q + +Q+ Q+ +Q++ Q+Q++Q+++Q+++ +Q++ K+ +E Q Q +
Sbjct: 152 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQ 209
Score = 37.4 bits (85), Expect = 0.035
Identities = 17/65 (26%), Positives = 40/65 (61%), Gaps = 1/65 (1%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQL 248
QEQ +Q + +Q+ Q+ +Q++ Q+Q++Q+++Q+++ +Q++ Q G++A Q
Sbjct: 143 QEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-QQQQQQQQHPGKQAKEQQ 201
Query: 249 QTDSE 253
Q +
Sbjct: 202 QQQQQ 206
Score = 36.6 bits (83), Expect = 0.060
Identities = 36/160 (22%), Positives = 81/160 (50%), Gaps = 12/160 (7%)
Query: 102 SFCQFTHYRCSNHVYYAKRVLCSQPVSIL-SPNTL-KEIEASAEVSPTTMTSPISPHFTV 159
S + H + + A+++L Q S L SP + K+ VS MT + +
Sbjct: 45 STVELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQV-----I 99
Query: 160 TERQTFQPWPERLSN--NVEELLQSSLSLGGQEQAPE--HKQEQGVEHRQEPTQEHKQEE 215
T +Q Q +++ + ++ LLQ ++ Q+Q + +K++Q H Q Q+ +Q++
Sbjct: 100 TPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQL-LQQQQQQQ 158
Query: 216 GQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSEPK 255
Q+Q++Q+++Q+++ +Q++ Q ++ ++ Q + K
Sbjct: 159 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAK 198
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 46.2 bits (108), Expect = 8e-05
Identities = 27/115 (23%), Positives = 62/115 (53%), Gaps = 5/115 (4%)
Query: 129 ILSPNTLKEIEASAEVSPTTMTSPISPHFTVTERQTFQPWPERLSNNVEELLQSSLSLGG 188
+++P +++I +SP + + + V +Q Q E E+L L L
Sbjct: 6 VITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQ--QQLQEFYKKQQEQL---HLQLLQ 60
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGRE 243
Q+Q + +Q+Q + +Q+ Q+ +Q++ Q+Q++Q+++Q+ GKQ + Q ++ ++
Sbjct: 61 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 115
Score = 39.7 bits (91), Expect = 0.007
Identities = 14/58 (24%), Positives = 38/58 (65%)
Query: 196 KQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSE 253
+Q+Q + +Q+ Q+ +Q++ Q+Q++Q+++Q+++ +Q++ K+ +E Q Q +
Sbjct: 60 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQ 117
Score = 37.4 bits (85), Expect = 0.035
Identities = 17/65 (26%), Positives = 40/65 (61%), Gaps = 1/65 (1%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQL 248
QEQ +Q + +Q+ Q+ +Q++ Q+Q++Q+++Q+++ +Q++ Q G++A Q
Sbjct: 51 QEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-QQQQQQQQHPGKQAKEQQ 109
Query: 249 QTDSE 253
Q +
Sbjct: 110 QQQQQ 114
Score = 34.7 bits (78), Expect = 0.23
Identities = 14/67 (20%), Positives = 40/67 (59%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQL 248
Q+Q E ++Q + + Q+ +Q++ Q+Q++Q+++Q+++ +Q++ Q ++ ++ Q
Sbjct: 40 QQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 99
Query: 249 QTDSEPK 255
+ K
Sbjct: 100 HPGKQAK 106
Score = 34.3 bits (77), Expect = 0.30
Identities = 22/119 (18%), Positives = 60/119 (50%), Gaps = 4/119 (3%)
Query: 169 PERLSNNVEELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEE 228
P++L +++ Q ++ L Q+ +K++Q H Q Q+ +Q+ Q+Q++Q+++Q++
Sbjct: 23 PQQLQALLQQ--QQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQ--QQQQQQQQQQQQ 78
Query: 229 EGKQEEGQGTKEGREAVSQLQTDSEPKFHSESLSSNPSSFAPRVREVESTPMIMENIQE 287
+ +Q++ Q ++ ++ Q Q + + A + + + M+ +Q+
Sbjct: 79 QQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQ 137
Score = 33.5 bits (75), Expect = 0.51
Identities = 26/139 (18%), Positives = 69/139 (49%), Gaps = 12/139 (8%)
Query: 189 QEQAPEHKQEQGVE-HRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQ 247
Q+QA +Q+Q E ++++ Q H Q Q+Q++Q+++Q+++ +Q++ Q ++ ++ Q
Sbjct: 32 QQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 91
Query: 248 LQTDSEPKFHSESLSSNPSSFAPRVREVESTPMIMENIQELIRSAQEIDEMNEIYDENSY 307
Q + + H + + +++ + ++ + Q++ +M ++ +
Sbjct: 92 QQQQQQQQ-HPGKQAKEQQQQQQQQQQLAAQQLVFQ---------QQLLQMQQLQQQQHL 141
Query: 308 WRNQNPGSLLQLPHTEALL 326
Q G L+ +P +A L
Sbjct: 142 LSLQRQG-LISIPPGQAAL 159
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 46.2 bits (108), Expect = 8e-05
Identities = 27/115 (23%), Positives = 62/115 (53%), Gaps = 5/115 (4%)
Query: 129 ILSPNTLKEIEASAEVSPTTMTSPISPHFTVTERQTFQPWPERLSNNVEELLQSSLSLGG 188
+++P +++I +SP + + + V +Q Q E E+L L L
Sbjct: 123 VITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQ--QQLQEFYKKQQEQL---HLQLLQ 177
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGRE 243
Q+Q + +Q+Q + +Q+ Q+ +Q++ Q+Q++Q+++Q+ GKQ + Q ++ ++
Sbjct: 178 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQ 232
Score = 39.7 bits (91), Expect = 0.007
Identities = 14/58 (24%), Positives = 38/58 (65%)
Query: 196 KQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSE 253
+Q+Q + +Q+ Q+ +Q++ Q+Q++Q+++Q+++ +Q++ K+ +E Q Q +
Sbjct: 177 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQ 234
Score = 37.4 bits (85), Expect = 0.035
Identities = 17/65 (26%), Positives = 40/65 (61%), Gaps = 1/65 (1%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQL 248
QEQ +Q + +Q+ Q+ +Q++ Q+Q++Q+++Q+++ +Q++ Q G++A Q
Sbjct: 168 QEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-QQQQQQQQHPGKQAKEQQ 226
Query: 249 QTDSE 253
Q +
Sbjct: 227 QQQQQ 231
Score = 34.7 bits (78), Expect = 0.23
Identities = 14/67 (20%), Positives = 40/67 (59%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQL 248
Q+Q E ++Q + + Q+ +Q++ Q+Q++Q+++Q+++ +Q++ Q ++ ++ Q
Sbjct: 157 QQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 216
Query: 249 QTDSEPK 255
+ K
Sbjct: 217 HPGKQAK 223
Score = 34.3 bits (77), Expect = 0.30
Identities = 43/208 (20%), Positives = 95/208 (45%), Gaps = 20/208 (9%)
Query: 125 QPVSILSPNTLKEI--EASAEVSP-TTMTSPISPHFTVTERQTFQPWPERLSNNV--EEL 179
+P+ L P T I +S + P T P+S + T Q + L V +
Sbjct: 83 RPLQELLPETKLCICGHSSGDGHPHNTFAVPVSVAMMTPQVITPQQMQQILQQQVLSPQQ 142
Query: 180 LQSSLSLGGQEQAPEHKQEQGVE-HRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGT 238
LQ+ L Q+QA +Q+Q E ++++ Q H Q Q+Q++Q+++Q+++ +Q++ Q
Sbjct: 143 LQALLQ---QQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQ 199
Query: 239 KEGREAVSQLQTDSEPKFHSESLSSNPSSFAPRVREVESTPMIMENIQELIRSAQEIDEM 298
++ ++ Q Q + + H + + +++ + ++ + Q++ +M
Sbjct: 200 QQQQQQQQQQQQQQQQQ-HPGKQAKEQQQQQQQQQQLAAQQLVFQ---------QQLLQM 249
Query: 299 NEIYDENSYWRNQNPGSLLQLPHTEALL 326
++ + Q G L+ +P +A L
Sbjct: 250 QQLQQQQHLLSLQRQG-LISIPPGQAAL 276
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 46.2 bits (108), Expect = 8e-05
Identities = 24/67 (35%), Positives = 38/67 (56%)
Query: 196 KQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSEPK 255
K E E +E +E ++ EG+++EE+ EE+EEEG + E G +E E + +D E +
Sbjct: 402 KSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEE 461
Query: 256 FHSESLS 262
ES S
Sbjct: 462 EDEESSS 468
Score = 40.4 bits (93), Expect = 0.004
Identities = 21/61 (34%), Positives = 36/61 (59%), Gaps = 2/61 (3%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEE--QEEEQEEEGKQEEGQGTKEGREAVS 246
+E+ E ++E+G +E E ++EEG + EE +EEE EEEG + + +E E+ S
Sbjct: 409 EEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSS 468
Query: 247 Q 247
+
Sbjct: 469 E 469
Score = 37.7 bits (86), Expect = 0.027
Identities = 21/64 (32%), Positives = 34/64 (53%)
Query: 180 LQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTK 239
+ +SL G+E+ E ++E+ E E +E +EE ++ E EE EEE +EEG
Sbjct: 397 ITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDS 456
Query: 240 EGRE 243
+ E
Sbjct: 457 DEEE 460
Score = 33.1 bits (74), Expect = 0.67
Identities = 15/56 (26%), Positives = 32/56 (57%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREA 244
+E E ++E+G E +E + + E ++ EE+ + +E ++E+ + + EG EA
Sbjct: 418 EEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEA 473
>gi|215490093 ATPase, (Na+)/K+ transporting, beta 4 polypeptide
isoform A [Homo sapiens]
Length = 357
Score = 46.2 bits (108), Expect = 8e-05
Identities = 24/57 (42%), Positives = 34/57 (59%)
Query: 197 QEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSE 253
+E+ E T K EE +++EE+EEE+EEE ++EEGQG G +LQ SE
Sbjct: 35 EEEEAEEEARVTVVPKSEEEEEEEEKEEEEEEEKEEEEGQGQPTGNAWWQKLQIMSE 91
>gi|6912256 ATPase, (Na+)/K+ transporting, beta 4 polypeptide
isoform B [Homo sapiens]
Length = 353
Score = 46.2 bits (108), Expect = 8e-05
Identities = 24/57 (42%), Positives = 34/57 (59%)
Query: 197 QEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSE 253
+E+ E T K EE +++EE+EEE+EEE ++EEGQG G +LQ SE
Sbjct: 35 EEEEAEEEARVTVVPKSEEEEEEEEKEEEEEEEKEEEEGQGQPTGNAWWQKLQIMSE 91
>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
Length = 185
Score = 45.8 bits (107), Expect = 1e-04
Identities = 18/47 (38%), Positives = 36/47 (76%)
Query: 197 QEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGRE 243
+E+ VE +E +E ++EE ++++E+EEE+EEE +++E + KEG++
Sbjct: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKK 165
Score = 44.3 bits (103), Expect = 3e-04
Identities = 22/60 (36%), Positives = 40/60 (66%), Gaps = 1/60 (1%)
Query: 194 EHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSE 253
E + E+ E +E +E ++EE +++EE+EEE+EE+ ++EE +G K E V + + D+E
Sbjct: 120 EEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEE-EIDTE 178
Score = 40.0 bits (92), Expect = 0.005
Identities = 17/61 (27%), Positives = 40/61 (65%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQL 248
+E+ E ++E E ++E +E ++EE +++E++E+E+EEE + ++ + K E +++
Sbjct: 120 EEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEI 179
Query: 249 Q 249
Q
Sbjct: 180 Q 180
Score = 37.0 bits (84), Expect = 0.046
Identities = 17/68 (25%), Positives = 39/68 (57%)
Query: 192 APEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTD 251
A E +QG+ +E +E ++E ++++E+E+E++EE +++E + ++ E + +
Sbjct: 107 AEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKM 166
Query: 252 SEPKFHSE 259
E K E
Sbjct: 167 EEEKVEEE 174
Score = 33.9 bits (76), Expect = 0.39
Identities = 17/63 (26%), Positives = 37/63 (58%)
Query: 177 EELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQ 236
EE+ + + +E+ E ++++ E ++E +E ++EE ++ ++ EEE+ EE E Q
Sbjct: 121 EEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQ 180
Query: 237 GTK 239
T+
Sbjct: 181 RTQ 183
>gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo
sapiens]
Length = 5033
Score = 45.4 bits (106), Expect = 1e-04
Identities = 18/53 (33%), Positives = 37/53 (69%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEG 241
+E+ E ++E+G E +E +E ++E Q++E++E+E+EE + E+ +G +EG
Sbjct: 1873 EEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEEG 1925
Score = 38.5 bits (88), Expect = 0.016
Identities = 19/64 (29%), Positives = 36/64 (56%)
Query: 177 EELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQ 236
+E ++ L + E E ++E+ E E E ++EE +++ QE+E EE+ ++E +
Sbjct: 1856 DEDVKQILKMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAE 1915
Query: 237 GTKE 240
G KE
Sbjct: 1916 GEKE 1919
Score = 36.2 bits (82), Expect = 0.079
Identities = 18/41 (43%), Positives = 28/41 (68%), Gaps = 1/41 (2%)
Query: 205 QEPTQEHKQEEGQKQEEQE-EEQEEEGKQEEGQGTKEGREA 244
+E +E ++EEG++++E+E EE EEE QE+ KE EA
Sbjct: 1873 EEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEA 1913
Score = 35.0 bits (79), Expect = 0.18
Identities = 14/35 (40%), Positives = 25/35 (71%)
Query: 219 QEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSE 253
+EE+EE++EEEG++E+ + +E E +Q + D E
Sbjct: 1873 EEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEE 1907
Score = 34.3 bits (77), Expect = 0.30
Identities = 16/51 (31%), Positives = 30/51 (58%)
Query: 193 PEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGRE 243
PE E+ E +E E + EE ++++E+E QE+E +++E + EG +
Sbjct: 1868 PEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEK 1918
Score = 33.5 bits (75), Expect = 0.51
Identities = 17/41 (41%), Positives = 23/41 (56%)
Query: 188 GQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEE 228
G+E+ E K+E E QE E K+EE + E+EE EE
Sbjct: 1884 GEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEE 1924
Score = 33.1 bits (74), Expect = 0.67
Identities = 14/46 (30%), Positives = 28/46 (60%)
Query: 208 TQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSE 253
T+E ++E+ +++ E+E+E+E+E +EE KE E + + E
Sbjct: 1872 TEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGE 1917
Score = 32.7 bits (73), Expect = 0.87
Identities = 14/38 (36%), Positives = 26/38 (68%)
Query: 206 EPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGRE 243
EP ++EE + +EE+ EE++EE K+E+ + T + +E
Sbjct: 1867 EPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKE 1904
Score = 31.2 bits (69), Expect = 2.5
Identities = 16/41 (39%), Positives = 23/41 (56%)
Query: 220 EEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSEPKFHSES 260
EE+EEE EEE +EE + KE E + + + E K E+
Sbjct: 1873 EEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEA 1913
>gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo
sapiens]
Length = 5038
Score = 45.4 bits (106), Expect = 1e-04
Identities = 18/53 (33%), Positives = 37/53 (69%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEG 241
+E+ E ++E+G E +E +E ++E Q++E++E+E+EE + E+ +G +EG
Sbjct: 1873 EEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEEG 1925
Score = 38.5 bits (88), Expect = 0.016
Identities = 19/64 (29%), Positives = 36/64 (56%)
Query: 177 EELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQ 236
+E ++ L + E E ++E+ E E E ++EE +++ QE+E EE+ ++E +
Sbjct: 1856 DEDVKQILKMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAE 1915
Query: 237 GTKE 240
G KE
Sbjct: 1916 GEKE 1919
Score = 36.2 bits (82), Expect = 0.079
Identities = 18/41 (43%), Positives = 28/41 (68%), Gaps = 1/41 (2%)
Query: 205 QEPTQEHKQEEGQKQEEQE-EEQEEEGKQEEGQGTKEGREA 244
+E +E ++EEG++++E+E EE EEE QE+ KE EA
Sbjct: 1873 EEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEA 1913
Score = 35.0 bits (79), Expect = 0.18
Identities = 14/35 (40%), Positives = 25/35 (71%)
Query: 219 QEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSE 253
+EE+EE++EEEG++E+ + +E E +Q + D E
Sbjct: 1873 EEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEE 1907
Score = 34.3 bits (77), Expect = 0.30
Identities = 16/51 (31%), Positives = 30/51 (58%)
Query: 193 PEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGRE 243
PE E+ E +E E + EE ++++E+E QE+E +++E + EG +
Sbjct: 1868 PEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEK 1918
Score = 33.5 bits (75), Expect = 0.51
Identities = 17/41 (41%), Positives = 23/41 (56%)
Query: 188 GQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEE 228
G+E+ E K+E E QE E K+EE + E+EE EE
Sbjct: 1884 GEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEE 1924
Score = 33.1 bits (74), Expect = 0.67
Identities = 14/46 (30%), Positives = 28/46 (60%)
Query: 208 TQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSE 253
T+E ++E+ +++ E+E+E+E+E +EE KE E + + E
Sbjct: 1872 TEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGE 1917
Score = 32.7 bits (73), Expect = 0.87
Identities = 14/38 (36%), Positives = 26/38 (68%)
Query: 206 EPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGRE 243
EP ++EE + +EE+ EE++EE K+E+ + T + +E
Sbjct: 1867 EPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKE 1904
Score = 31.2 bits (69), Expect = 2.5
Identities = 16/41 (39%), Positives = 23/41 (56%)
Query: 220 EEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSEPKFHSES 260
EE+EEE EEE +EE + KE E + + + E K E+
Sbjct: 1873 EEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEA 1913
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 45.4 bits (106), Expect = 1e-04
Identities = 27/98 (27%), Positives = 51/98 (52%), Gaps = 5/98 (5%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQL 248
+E+ E ++E+ E +E +E+ +EE +++EE EEE EEE + E + +E E +L
Sbjct: 898 EEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEEL 957
Query: 249 QTDSEPKFHS-----ESLSSNPSSFAPRVREVESTPMI 281
+ + +F + E + P + P + ES P +
Sbjct: 958 EEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKV 995
Score = 44.7 bits (104), Expect = 2e-04
Identities = 22/80 (27%), Positives = 45/80 (56%)
Query: 180 LQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTK 239
L+ L++ + E ++E+ E +E +E ++E+ +++EE EEE EE ++EE + +
Sbjct: 874 LEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEE 933
Query: 240 EGREAVSQLQTDSEPKFHSE 259
E E +L+ + E + E
Sbjct: 934 EFEEEEGELEEEEEEEDEEE 953
Score = 43.1 bits (100), Expect = 6e-04
Identities = 23/85 (27%), Positives = 46/85 (54%)
Query: 177 EELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQ 236
E+L +++ +E+ E ++E+ E +E ++ ++EE ++E EEE+EEE + EE
Sbjct: 876 EDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEF 935
Query: 237 GTKEGREAVSQLQTDSEPKFHSESL 261
+EG + + D E + E +
Sbjct: 936 EEEEGELEEEEEEEDEEEEEELEEV 960
Score = 40.0 bits (92), Expect = 0.005
Identities = 20/67 (29%), Positives = 39/67 (58%)
Query: 193 PEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDS 252
P +++ V + +E ++EE +++EE+EEE+EEE +EE + +E E + + +
Sbjct: 872 PALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEF 931
Query: 253 EPKFHSE 259
E +F E
Sbjct: 932 EEEFEEE 938
Score = 33.9 bits (76), Expect = 0.39
Identities = 18/68 (26%), Positives = 36/68 (52%), Gaps = 1/68 (1%)
Query: 187 GGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQE-EEGKQEEGQGTKEGREAV 245
GG E + E +E ++EE +++EE+EEE++ EE +++E + +E E
Sbjct: 869 GGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEE 928
Query: 246 SQLQTDSE 253
+ + + E
Sbjct: 929 EEFEEEFE 936
Score = 33.5 bits (75), Expect = 0.51
Identities = 19/75 (25%), Positives = 36/75 (48%)
Query: 202 EHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSEPKFHSESL 261
+ +E +E ++EE +++EE+E+ +EEE +EE +E E + + + E E
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946
Query: 262 SSNPSSFAPRVREVE 276
+ EVE
Sbjct: 947 EEEDEEEEEELEEVE 961
Score = 30.8 bits (68), Expect = 3.3
Identities = 21/88 (23%), Positives = 37/88 (42%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQL 248
+E+ E + E+ E + +E ++EE +++EE+ EE E+ G +EG L
Sbjct: 923 EEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTL 982
Query: 249 QTDSEPKFHSESLSSNPSSFAPRVREVE 276
P + P + EVE
Sbjct: 983 PPALPPPESPPKVQPEPEPEPGLLLEVE 1010
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 45.4 bits (106), Expect = 1e-04
Identities = 37/168 (22%), Positives = 82/168 (48%), Gaps = 18/168 (10%)
Query: 152 PISPHFTVTERQTFQPWPERL-------SNNVEELLQSSLSLGGQEQAPEHKQEQGVEHR 204
P++ ++Q +P P+R S++V+E S G E E ++++G E+
Sbjct: 56 PLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSD----GTEDMDEKEEDEGEEYS 111
Query: 205 Q---EPTQEHKQ-EEGQKQEEQEEEQEEEGKQEEGQGTK-EGREAVSQLQTDSEPKFHSE 259
+ EP E ++ EEG ++EE+E E+E+E E+G+ + E E + + + E +
Sbjct: 112 EDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDH 171
Query: 260 SLSSNPSSFAPRVREVESTPMIMENIQELIRSAQEIDEMNEIYDENSY 307
++ + + + ++ +N EL+ A+ + + +I ++ +Y
Sbjct: 172 QMNCHNTRIMQDTEKDDNNNDEYDNYDELV--AKSLLNLGKIAEDAAY 217
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 45.1 bits (105), Expect = 2e-04
Identities = 33/142 (23%), Positives = 63/142 (44%), Gaps = 12/142 (8%)
Query: 170 ERLSNNVEELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEE 229
E S +E LL L QE ++E+ E + +E ++EE +++EE+E E+++
Sbjct: 2224 EHFSEEMESLLDE---LEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQV 2280
Query: 230 GKQEEGQGTKEGREAVSQLQTDSEPKFHSESLSSNPSSFAPRVREVESTPMIMENIQELI 289
K+EE + K+ + ++Q E E + S + + E E +E
Sbjct: 2281 EKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLE------ 2334
Query: 290 RSAQEIDEMNEIYDENSYWRNQ 311
+E+D EI + ++ Q
Sbjct: 2335 ---EEVDREKEILKKEKQFKLQ 2353
Score = 43.9 bits (102), Expect = 4e-04
Identities = 32/108 (29%), Positives = 63/108 (58%), Gaps = 6/108 (5%)
Query: 159 VTERQTFQPWPERLSNNVEEL-LQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQ 217
V E ++ + + E + + ++EL Q SLS +E+ E ++ + E R+E + ++EEG+
Sbjct: 2217 VDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGE 2276
Query: 218 KQEEQEEEQEEEGKQEEGQGTKE---GREAVSQLQTDSEPKFHSESLS 262
E+Q E++EEE K+++ + KE +E V + + + + +ESLS
Sbjct: 2277 --EKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLS 2322
Score = 34.7 bits (78), Expect = 0.23
Identities = 27/84 (32%), Positives = 44/84 (52%), Gaps = 7/84 (8%)
Query: 166 QPWPERLSNNVEELLQSSLSLGGQEQA-PEHKQEQGVEHRQ--EPTQEHKQEEGQKQEEQ 222
+ W +RL E+L Q+ L +E+ E K+ + E +Q E K +E Q ++E+
Sbjct: 1483 EEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEE 1542
Query: 223 E----EEQEEEGKQEEGQGTKEGR 242
E EE EG+++E Q T+E R
Sbjct: 1543 EVTLEEEVSREGEEKEQQVTEEQR 1566
Score = 34.3 bits (77), Expect = 0.30
Identities = 29/136 (21%), Positives = 63/136 (46%), Gaps = 20/136 (14%)
Query: 170 ERLSNNVEELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEE- 228
E+ S+ V+E+ E+ + E ++ ++ +EE +++EE+E E+EE
Sbjct: 2211 EKFSSQVDEV--------ESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEV 2262
Query: 229 EGKQEEGQGTKEGREAVSQLQTDSEPKFHSESLSSNPSSFAPRVREVESTPMIMENIQEL 288
++EE + +EG E + + + + K E + EV+ + E +E
Sbjct: 2263 REEEEERKEEEEGEEKQVEKEEEEKKKKKKEK----------KKEEVQEKEEVFEEKEE- 2311
Query: 289 IRSAQEIDEMNEIYDE 304
I S +E + +++ +E
Sbjct: 2312 IMSEEETESLSDEEEE 2327
Score = 31.2 bits (69), Expect = 2.5
Identities = 32/134 (23%), Positives = 57/134 (42%), Gaps = 10/134 (7%)
Query: 172 LSNNVEELLQSSLSLGGQEQAPEHKQEQ---GVEHRQEPTQEHKQEEGQKQEEQEEEQEE 228
L+ VEEL Q +L QE+ + E+ +E +E QEEG+ EE+++ EE
Sbjct: 1693 LAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEE 1752
Query: 229 E------GKQEEGQGTKEGREAVSQLQTDSEPKFHSESLSSNPSSFA-PRVREVESTPMI 281
E ++ + TK +E +Q + H E + R + +E +
Sbjct: 1753 EEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKL 1812
Query: 282 MENIQELIRSAQEI 295
+ + I S +E+
Sbjct: 1813 AQKRERWINSMEEL 1826
Score = 30.0 bits (66), Expect = 5.6
Identities = 17/52 (32%), Positives = 32/52 (61%), Gaps = 2/52 (3%)
Query: 177 EELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEE 228
+++ ++ LS +EQ ++K E+ V +E ++E +++E Q EEQ QEE
Sbjct: 1522 KQVWENMLSSKSKEQ--QYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEE 1571
Score = 30.0 bits (66), Expect = 5.6
Identities = 29/98 (29%), Positives = 45/98 (45%), Gaps = 25/98 (25%)
Query: 166 QPWPERLSNNVEE---------LLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHK---- 212
Q W LS+ +E L+ +S G+E K++Q E ++ +EHK
Sbjct: 1523 QVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEE-----KEQQVTEEQRHIQEEHKWARI 1577
Query: 213 ------QEEGQKQEEQEEEQEEEG-KQEEGQGTKEGRE 243
E+ + QEE++ QEEE QEE Q +E R+
Sbjct: 1578 HRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERK 1615
Score = 29.6 bits (65), Expect = 7.4
Identities = 24/132 (18%), Positives = 56/132 (42%), Gaps = 8/132 (6%)
Query: 173 SNNVEELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQ 232
S EL + L +++ +K + + ++ T+E + + E +++EE G +
Sbjct: 2126 SEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIE 2185
Query: 233 EEGQGTKEGREAVSQLQTDSEPKFHSESLSSNPSSFAPRVREVESTPMIMENIQELIRSA 292
EE E + L+ + ++ F+ +V EVES E ++ L+
Sbjct: 2186 EE--------EVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDEL 2237
Query: 293 QEIDEMNEIYDE 304
++ + ++ +E
Sbjct: 2238 EKQESLSSEEEE 2249
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 45.1 bits (105), Expect = 2e-04
Identities = 25/89 (28%), Positives = 48/89 (53%), Gaps = 5/89 (5%)
Query: 170 ERLSNNVEELLQSSLSLGGQEQAPEHKQEQGVEH-----RQEPTQEHKQEEGQKQEEQEE 224
E++ E++ + +G QE+ ++EQ E +QE + ++E+ +KQEEQ
Sbjct: 206 EQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMR 265
Query: 225 EQEEEGKQEEGQGTKEGREAVSQLQTDSE 253
EQEE+ +++E Q K+ + + QT +
Sbjct: 266 EQEEQMREQEEQMLKQKEQTEQEEQTGEQ 294
Score = 42.4 bits (98), Expect = 0.001
Identities = 28/97 (28%), Positives = 51/97 (52%), Gaps = 7/97 (7%)
Query: 162 RQTFQPWP--ERLSNNVEELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQ 219
+Q Q W E++ E++ + +G QE+ + ++EQ +QE ++E+ +KQ
Sbjct: 328 KQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQ--VRKQEEQMRKQEEQMRKQ 385
Query: 220 EEQEEEQEE---EGKQEEGQGTKEGREAVSQLQTDSE 253
EEQ +QEE E K++ G+ ++ RE Q+ E
Sbjct: 386 EEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKE 422
Score = 42.0 bits (97), Expect = 0.001
Identities = 25/91 (27%), Positives = 49/91 (53%), Gaps = 5/91 (5%)
Query: 170 ERLSNNVEELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQ-----EEGQKQEEQEE 224
E++ E++ + +G QE+ ++EQ E +++ ++ +Q E+ QKQEEQ
Sbjct: 310 EQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVR 369
Query: 225 EQEEEGKQEEGQGTKEGREAVSQLQTDSEPK 255
+QEE+ +++E Q K+ + Q + E K
Sbjct: 370 KQEEQMRKQEEQMRKQEEQMRKQEEQMGEQK 400
Score = 40.8 bits (94), Expect = 0.003
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 11/124 (8%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEE-GKQEEGQGTKEGREAVSQ 247
+EQ + +++G QE ++E+ QKQEEQ EQEE+ KQEE G +E Q
Sbjct: 188 REQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQE-----EQ 242
Query: 248 LQTDSEPKFHSESLSSNPSSFAPRVREVESTPMIMENIQELIRSAQEIDEMNEIYDENSY 307
+Q E E ++RE E + E +++++ ++ ++ + ++
Sbjct: 243 VQKQEEQVQKQEEQMRKQEE---QMREQEE--QMREQEEQMLKQKEQTEQEEQTGEQEEQ 297
Query: 308 WRNQ 311
R Q
Sbjct: 298 MREQ 301
Score = 40.4 bits (93), Expect = 0.004
Identities = 28/149 (18%), Positives = 70/149 (46%), Gaps = 9/149 (6%)
Query: 161 ERQTFQPWPERLSNNVEELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQE 220
+ + Q E++ E++ + +G QE+ + ++EQ + ++ ++ +Q Q+++
Sbjct: 211 QEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQ 270
Query: 221 EQEEE-----QEEEGKQEEGQGTKEG--REAVSQLQTDSEP-KFHSESLSSNPSSFAPRV 272
+E+E Q+E+ +QEE G +E RE Q++ E + E + +
Sbjct: 271 MREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQE 330
Query: 273 REV-ESTPMIMENIQELIRSAQEIDEMNE 300
++ E + E +++ + +++ E E
Sbjct: 331 EQMWEQKEQMWEQKEQMWKQEEQMGEQEE 359
Score = 39.7 bits (91), Expect = 0.007
Identities = 24/135 (17%), Positives = 61/135 (45%), Gaps = 1/135 (0%)
Query: 161 ERQTFQPWPERLSNNVEELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQE 220
+ + Q E++ E++ + + QE+ ++EQ ++ +++ QE + E ++Q
Sbjct: 239 QEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQM 298
Query: 221 EQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSEPKF-HSESLSSNPSSFAPRVREVESTP 279
++EEQ E +++ + ++ RE Q+ E + E + + ++
Sbjct: 299 REQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQE 358
Query: 280 MIMENIQELIRSAQE 294
M+ +E +R +E
Sbjct: 359 EQMQKQEEQVRKQEE 373
Score = 37.7 bits (86), Expect = 0.027
Identities = 18/71 (25%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
Query: 170 ERLSNNVEELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEE 229
E++ E++ + + QE+ KQE+ + ++E E K++ G+++E+ E++E+
Sbjct: 359 EQMQKQEEQVRKQEEQMRKQEEQMR-KQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQM 417
Query: 230 GKQEEGQGTKE 240
G+Q+E +E
Sbjct: 418 GEQKEQMRKQE 428
Score = 37.4 bits (85), Expect = 0.035
Identities = 22/110 (20%), Positives = 52/110 (47%), Gaps = 1/110 (0%)
Query: 186 LGGQEQAPEHKQEQ-GVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREA 244
+G QE+ + ++EQ G + Q QE + E ++Q +++EEQ ++ +++ + ++ RE
Sbjct: 208 MGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQ 267
Query: 245 VSQLQTDSEPKFHSESLSSNPSSFAPRVREVESTPMIMENIQELIRSAQE 294
Q++ E + + + ++ M +E +R +E
Sbjct: 268 EEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEE 317
Score = 37.4 bits (85), Expect = 0.035
Identities = 32/142 (22%), Positives = 60/142 (42%), Gaps = 8/142 (5%)
Query: 161 ERQTFQPWPERLSNNVEELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQ- 219
+ + Q E++ E++ + + QE+ ++EQ + Q QE + E ++Q
Sbjct: 246 QEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQM 305
Query: 220 EEQEE---EQEEEGKQEEGQGTKEGREAVSQLQTDSEPK----FHSESLSSNPSSFAPRV 272
EQEE EQEE+ +++E Q K+ + Q + E K E + +
Sbjct: 306 REQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQE 365
Query: 273 REVESTPMIMENIQELIRSAQE 294
+V M +E +R +E
Sbjct: 366 EQVRKQEEQMRKQEEQMRKQEE 387
Score = 36.2 bits (82), Expect = 0.079
Identities = 33/148 (22%), Positives = 68/148 (45%), Gaps = 20/148 (13%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEG--KQEEGQ-GTKEGR--- 242
+EQ + ++++G QE + +++EGQ +E++ + +E+EG +++EGQ G +EG+
Sbjct: 146 REQEGQVREQEGQVREQEG--QVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGE 203
Query: 243 ------EAVSQLQTDSEPK-FHSESLSSNPSSFAPRVREVESTPMIMENIQELIRSAQEI 295
E Q+Q E E + + +V+ ++ +E +R +E
Sbjct: 204 QEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEE- 262
Query: 296 DEMNEIYDENSYWRNQNPGSLLQLPHTE 323
++ ++ R Q L Q TE
Sbjct: 263 ----QMREQEEQMREQEEQMLKQKEQTE 286
Score = 35.8 bits (81), Expect = 0.10
Identities = 29/120 (24%), Positives = 54/120 (45%), Gaps = 8/120 (6%)
Query: 186 LGGQE-QAPEHKQEQGVEHRQEPTQEHK---QEEGQK-QEEQEEEQEEEGKQEEGQGTKE 240
+G QE Q E +++ G + Q QE + QEE + QEEQ EQEE+ +++E Q K+
Sbjct: 194 MGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQ 253
Query: 241 GREAVSQLQTDSEPKFHSESLSSNPSSFAPRVREVESTPMIMENIQELIRSAQEIDEMNE 300
+ Q + + + E + + + E E +++ +++ E E
Sbjct: 254 EEQMRKQ---EEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEE 310
Score = 35.8 bits (81), Expect = 0.10
Identities = 19/80 (23%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
Query: 161 ERQTFQPWPERLSNNVEELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQE 220
+ + Q E++ E++ + + QE+ KQE+ + ++E E K++ +++E
Sbjct: 357 QEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMR-KQEEQMGEQKEQMGEQKEQMREQEE 415
Query: 221 EQEEEQEEEGKQEEGQGTKE 240
+ E++E+ KQEE G ++
Sbjct: 416 QMGEQKEQMRKQEEHMGEQK 435
Score = 33.1 bits (74), Expect = 0.67
Identities = 20/83 (24%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
Query: 158 TVTERQTFQPWPERLSNNVEELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQ 217
T E QT + E++ E++ + + QE+ ++EQ + ++E E K++ +
Sbjct: 285 TEQEEQTGEQ-EEQMREQEEQMREQEEQMREQEEQMREQEEQ-MGKQEEQMWEQKEQMWE 342
Query: 218 KQEEQEEEQEEEGKQEEGQGTKE 240
++E+ +++E+ G+QEE +E
Sbjct: 343 QKEQMWKQEEQMGEQEEQMQKQE 365
Score = 32.7 bits (73), Expect = 0.87
Identities = 13/46 (28%), Positives = 31/46 (67%), Gaps = 2/46 (4%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEE 234
+EQ E K++ G ++E +E +++ G+++E+ +++E G+Q+E
Sbjct: 393 EEQMGEQKEQMG--EQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 31.2 bits (69), Expect = 2.5
Identities = 15/55 (27%), Positives = 34/55 (61%), Gaps = 2/55 (3%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGRE 243
+EQ + ++++G QE + +++EGQ +E++ + +E+EG+ E +G +E
Sbjct: 55 REQEGQVREQEGQVREQEG--QVREQEGQVREQEGQVREQEGQVREQEGQVREQE 107
Score = 31.2 bits (69), Expect = 2.5
Identities = 14/48 (29%), Positives = 29/48 (60%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQ 236
+EQ + ++++G QE ++ + ++QE Q EQE + +++EGQ
Sbjct: 62 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 109
Score = 31.2 bits (69), Expect = 2.5
Identities = 14/48 (29%), Positives = 29/48 (60%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQ 236
+EQ + ++++G QE ++ + ++QE Q EQE + +++EGQ
Sbjct: 69 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 116
Score = 31.2 bits (69), Expect = 2.5
Identities = 14/48 (29%), Positives = 29/48 (60%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQ 236
+EQ + ++++G QE ++ + ++QE Q EQE + +++EGQ
Sbjct: 76 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 123
Score = 31.2 bits (69), Expect = 2.5
Identities = 15/55 (27%), Positives = 34/55 (61%), Gaps = 2/55 (3%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGRE 243
+EQ + ++++G QE + +++EGQ +E++ + +E+EG+ E +G +E
Sbjct: 83 REQEGQVREQEGQVREQEG--QVREQEGQVREQEGQVREQEGQVREQEGQVREQE 135
Score = 31.2 bits (69), Expect = 2.5
Identities = 14/48 (29%), Positives = 29/48 (60%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQ 236
+EQ + ++++G QE ++ + ++QE Q EQE + +++EGQ
Sbjct: 90 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 137
Score = 31.2 bits (69), Expect = 2.5
Identities = 14/48 (29%), Positives = 29/48 (60%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQ 236
+EQ + ++++G QE ++ + ++QE Q EQE + +++EGQ
Sbjct: 97 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 144
Score = 31.2 bits (69), Expect = 2.5
Identities = 14/48 (29%), Positives = 29/48 (60%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQ 236
+EQ + ++++G QE ++ + ++QE Q EQE + +++EGQ
Sbjct: 104 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 151
Score = 31.2 bits (69), Expect = 2.5
Identities = 14/48 (29%), Positives = 29/48 (60%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQ 236
+EQ + ++++G QE ++ + ++QE Q EQE + +++EGQ
Sbjct: 111 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 158
Score = 31.2 bits (69), Expect = 2.5
Identities = 15/55 (27%), Positives = 34/55 (61%), Gaps = 2/55 (3%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGRE 243
+EQ + ++++G QE + +++EGQ +E++ + +E+EG+ E +G +E
Sbjct: 118 REQEGQVREQEGQVREQEG--QVREQEGQVREQEGQVREQEGQVREQEGQVREQE 170
Score = 31.2 bits (69), Expect = 2.5
Identities = 15/55 (27%), Positives = 34/55 (61%), Gaps = 2/55 (3%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGRE 243
+EQ + ++++G QE + +++EGQ +E++ + +E+EG+ E +G +E
Sbjct: 125 REQEGQVREQEGQVREQEG--QVREQEGQVREQEGQVREQEGQVREQEGQVREQE 177
Score = 30.8 bits (68), Expect = 3.3
Identities = 24/142 (16%), Positives = 62/142 (43%), Gaps = 8/142 (5%)
Query: 158 TVTERQTFQPWPERLSNNVEELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQ 217
T + + + E++ E++ + + QE+ ++EQ E +++ ++ +Q Q
Sbjct: 291 TGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQ 350
Query: 218 KQEEQEEE-----QEEEGKQEEGQGTKEGREAVSQLQTDSEPKFHSESLSSNPSSFAPRV 272
+++ E+E QEE+ +++E Q K+ + Q + + + E + +
Sbjct: 351 EEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQ---EEQMRKQEEQMGEQKEQMGEQK 407
Query: 273 REVESTPMIMENIQELIRSAQE 294
++ M +E +R +E
Sbjct: 408 EQMREQEEQMGEQKEQMRKQEE 429
>gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Homo
sapiens]
Length = 1108
Score = 45.1 bits (105), Expect = 2e-04
Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 2/92 (2%)
Query: 185 SLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEE-GQGTKEGRE 243
SL +E K+E+ + E QE K+ E + +E+EEE+EEE ++EE + EG E
Sbjct: 1011 SLTREEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEE 1070
Query: 244 AVSQ-LQTDSEPKFHSESLSSNPSSFAPRVRE 274
A ++ L D + + SL + +V E
Sbjct: 1071 AKTEGLMKDDRAESQASSLGQKVGESSEQVSE 1102
Score = 37.7 bits (86), Expect = 0.027
Identities = 28/120 (23%), Positives = 48/120 (40%)
Query: 132 PNTLKEIEASAEVSPTTMTSPISPHFTVTERQTFQPWPERLSNNVEELLQSSLSLGGQEQ 191
P L A SP+ S T E + + E +EEL + Q
Sbjct: 987 PEILSNEHVGARASPSQGDSDERESLTREEDEDSEKEEEEEDKEMEELQEEKECEKPQGD 1046
Query: 192 APEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTD 251
E ++E+ VE + E++ EE + + ++++ E GQ E E VS+ +T+
Sbjct: 1047 EEEEEEEEEVEEEEVEEAENEGEEAKTEGLMKDDRAESQASSLGQKVGESSEQVSEEKTN 1106
Score = 33.1 bits (74), Expect = 0.67
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 6/94 (6%)
Query: 170 ERLSNNVEELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQE----EE 225
ER S EE LS + QG +E + E+ +K+EE+E EE
Sbjct: 976 ERDSTEQEEAGPEILS--NEHVGARASPSQGDSDERESLTREEDEDSEKEEEEEDKEMEE 1033
Query: 226 QEEEGKQEEGQGTKEGREAVSQLQTDSEPKFHSE 259
+EE + E+ QG +E E +++ + + +E
Sbjct: 1034 LQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENE 1067
Score = 31.2 bits (69), Expect = 2.5
Identities = 22/97 (22%), Positives = 41/97 (42%), Gaps = 1/97 (1%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQE-EGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQ 247
+E PE + V R P+Q E E +EE E+ ++EE ++++ + + +
Sbjct: 983 EEAGPEILSNEHVGARASPSQGDSDERESLTREEDEDSEKEEEEEDKEMEELQEEKECEK 1042
Query: 248 LQTDSEPKFHSESLSSNPSSFAPRVREVESTPMIMEN 284
Q D E + E + A E T +M++
Sbjct: 1043 PQGDEEEEEEEEEVEEEEVEEAENEGEEAKTEGLMKD 1079
>gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Homo
sapiens]
Length = 1124
Score = 45.1 bits (105), Expect = 2e-04
Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 2/92 (2%)
Query: 185 SLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEE-GQGTKEGRE 243
SL +E K+E+ + E QE K+ E + +E+EEE+EEE ++EE + EG E
Sbjct: 1027 SLTREEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEE 1086
Query: 244 AVSQ-LQTDSEPKFHSESLSSNPSSFAPRVRE 274
A ++ L D + + SL + +V E
Sbjct: 1087 AKTEGLMKDDRAESQASSLGQKVGESSEQVSE 1118
Score = 37.7 bits (86), Expect = 0.027
Identities = 28/120 (23%), Positives = 48/120 (40%)
Query: 132 PNTLKEIEASAEVSPTTMTSPISPHFTVTERQTFQPWPERLSNNVEELLQSSLSLGGQEQ 191
P L A SP+ S T E + + E +EEL + Q
Sbjct: 1003 PEILSNEHVGARASPSQGDSDERESLTREEDEDSEKEEEEEDKEMEELQEEKECEKPQGD 1062
Query: 192 APEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTD 251
E ++E+ VE + E++ EE + + ++++ E GQ E E VS+ +T+
Sbjct: 1063 EEEEEEEEEVEEEEVEEAENEGEEAKTEGLMKDDRAESQASSLGQKVGESSEQVSEEKTN 1122
Score = 33.1 bits (74), Expect = 0.67
Identities = 25/94 (26%), Positives = 42/94 (44%), Gaps = 6/94 (6%)
Query: 170 ERLSNNVEELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQE----EE 225
ER S EE LS + QG +E + E+ +K+EE+E EE
Sbjct: 992 ERDSTEQEEAGPEILS--NEHVGARASPSQGDSDERESLTREEDEDSEKEEEEEDKEMEE 1049
Query: 226 QEEEGKQEEGQGTKEGREAVSQLQTDSEPKFHSE 259
+EE + E+ QG +E E +++ + + +E
Sbjct: 1050 LQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENE 1083
Score = 31.2 bits (69), Expect = 2.5
Identities = 22/97 (22%), Positives = 41/97 (42%), Gaps = 1/97 (1%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQE-EGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQ 247
+E PE + V R P+Q E E +EE E+ ++EE ++++ + + +
Sbjct: 999 EEAGPEILSNEHVGARASPSQGDSDERESLTREEDEDSEKEEEEEDKEMEELQEEKECEK 1058
Query: 248 LQTDSEPKFHSESLSSNPSSFAPRVREVESTPMIMEN 284
Q D E + E + A E T +M++
Sbjct: 1059 PQGDEEEEEEEEEVEEEEVEEAENEGEEAKTEGLMKD 1095
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
isoform b [Homo sapiens]
Length = 1176
Score = 45.1 bits (105), Expect = 2e-04
Identities = 21/55 (38%), Positives = 34/55 (61%)
Query: 198 EQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDS 252
EQ E +E +E ++EE +++EE+EEE EE G Q + G+ R+A + + DS
Sbjct: 296 EQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWRKDS 350
Score = 39.7 bits (91), Expect = 0.007
Identities = 20/66 (30%), Positives = 38/66 (57%)
Query: 201 VEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSEPKFHSES 260
VE E E ++EE +++EE+EEE+EEE ++E+ + + + S + ++ K+ +S
Sbjct: 291 VEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWRKDS 350
Query: 261 LSSNPS 266
PS
Sbjct: 351 PWVKPS 356
Score = 35.4 bits (80), Expect = 0.13
Identities = 24/107 (22%), Positives = 44/107 (41%)
Query: 177 EELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQ 236
E ++ SL + + + + + E E EE +++EE+EEE+EEE ++EE +
Sbjct: 263 ETVVGDDFSLYYDSYSVDERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEE 322
Query: 237 GTKEGREAVSQLQTDSEPKFHSESLSSNPSSFAPRVREVESTPMIME 283
+E + + K + +P R R P E
Sbjct: 323 EDEESGNQSDRSGSSGRRKAKKKWRKDSPWVKPSRKRRKREPPRAKE 369
>gi|156142197 euchromatic histone-lysine N-methyltransferase 2
isoform a [Homo sapiens]
Length = 1210
Score = 45.1 bits (105), Expect = 2e-04
Identities = 21/55 (38%), Positives = 34/55 (61%)
Query: 198 EQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDS 252
EQ E +E +E ++EE +++EE+EEE EE G Q + G+ R+A + + DS
Sbjct: 296 EQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWRKDS 350
Score = 39.7 bits (91), Expect = 0.007
Identities = 20/66 (30%), Positives = 38/66 (57%)
Query: 201 VEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSEPKFHSES 260
VE E E ++EE +++EE+EEE+EEE ++E+ + + + S + ++ K+ +S
Sbjct: 291 VEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWRKDS 350
Query: 261 LSSNPS 266
PS
Sbjct: 351 PWVKPS 356
Score = 35.4 bits (80), Expect = 0.13
Identities = 24/107 (22%), Positives = 44/107 (41%)
Query: 177 EELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQ 236
E ++ SL + + + + + E E EE +++EE+EEE+EEE ++EE +
Sbjct: 263 ETVVGDDFSLYYDSYSVDERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEE 322
Query: 237 GTKEGREAVSQLQTDSEPKFHSESLSSNPSSFAPRVREVESTPMIME 283
+E + + K + +P R R P E
Sbjct: 323 EDEESGNQSDRSGSSGRRKAKKKWRKDSPWVKPSRKRRKREPPRAKE 369
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 45.1 bits (105), Expect = 2e-04
Identities = 23/63 (36%), Positives = 38/63 (60%), Gaps = 6/63 (9%)
Query: 187 GGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEG------KQEEGQGTKE 240
GG+ + E ++ +G +E E ++EEG+ +EE+ E +EEEG + EEG+G +E
Sbjct: 811 GGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEE 870
Query: 241 GRE 243
G E
Sbjct: 871 GEE 873
Score = 43.5 bits (101), Expect = 5e-04
Identities = 23/66 (34%), Positives = 40/66 (60%), Gaps = 1/66 (1%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEE-EQEEEGKQEEGQGTKEGREAVSQ 247
+E+ E ++E+G +E E ++ EG+ +EE EE E EEEG++ EG+G +E E +
Sbjct: 829 EEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGE 888
Query: 248 LQTDSE 253
+ + E
Sbjct: 889 EEGEGE 894
Score = 42.7 bits (99), Expect = 8e-04
Identities = 22/56 (39%), Positives = 36/56 (64%), Gaps = 1/56 (1%)
Query: 188 GQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGRE 243
G+E+ E ++E+G E +E + +EEG++ E +EE +E EG+ EE +G EG E
Sbjct: 835 GEEEEGEGEEEEG-EGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEE 889
Score = 42.0 bits (97), Expect = 0.001
Identities = 26/94 (27%), Positives = 45/94 (47%), Gaps = 3/94 (3%)
Query: 166 QPWPERLSNNVEELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEE 225
+ W +R + EE Q G Q++ + +E G E E +E E ++++E E +
Sbjct: 700 EEWKKR---DGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGK 756
Query: 226 QEEEGKQEEGQGTKEGREAVSQLQTDSEPKFHSE 259
+E EG++ EG+ KE E + + E K E
Sbjct: 757 EEGEGEEVEGEREKEEGERKKEERAGKEEKGEEE 790
Score = 41.6 bits (96), Expect = 0.002
Identities = 21/66 (31%), Positives = 38/66 (57%)
Query: 188 GQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQ 247
G+E+ + E G + +E ++EEG+ +EE+ E +EEEG+ EE +G +G E +
Sbjct: 805 GEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEE 864
Query: 248 LQTDSE 253
+ + E
Sbjct: 865 GEGEEE 870
Score = 41.2 bits (95), Expect = 0.002
Identities = 26/68 (38%), Positives = 40/68 (58%), Gaps = 13/68 (19%)
Query: 188 GQEQAPEHKQEQGVEHRQEPTQ---EHKQEEGQ---------KQEEQEEEQEEEGKQEEG 235
G+E+ E + +QG E +E T+ E K+E G+ K E +EEE+E EG++EEG
Sbjct: 782 GKEEKGEEEGDQG-EGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEG 840
Query: 236 QGTKEGRE 243
+G +E E
Sbjct: 841 EGEEEEGE 848
Score = 40.8 bits (94), Expect = 0.003
Identities = 22/57 (38%), Positives = 36/57 (63%), Gaps = 1/57 (1%)
Query: 188 GQEQAPEHKQEQGV-EHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGRE 243
G+E E ++E+G E +E E ++EEG+ + E+E E E E ++ EG+G +EG E
Sbjct: 871 GEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEE 927
Score = 40.8 bits (94), Expect = 0.003
Identities = 24/61 (39%), Positives = 37/61 (60%), Gaps = 4/61 (6%)
Query: 187 GGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQ---KQEEQEEEQEEEGK-QEEGQGTKEGR 242
G +E+ +E+G +E E ++EEG+ ++EE EEE EEEG+ +EEG+G E
Sbjct: 957 GEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEE 1016
Query: 243 E 243
E
Sbjct: 1017 E 1017
Score = 40.0 bits (92), Expect = 0.005
Identities = 21/60 (35%), Positives = 38/60 (63%), Gaps = 4/60 (6%)
Query: 188 GQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQE----EEQEEEGKQEEGQGTKEGRE 243
G+E+ E + E+ E + E ++ +G+++EE+E EE+E EG++EEG+G +E E
Sbjct: 796 GEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGE 855
Score = 40.0 bits (92), Expect = 0.005
Identities = 22/68 (32%), Positives = 39/68 (57%), Gaps = 3/68 (4%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQG---TKEGREAV 245
+E E ++E+G E +E + ++ EG+ +EE+E E E E + EEG+G +EG E
Sbjct: 984 EEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEG 1043
Query: 246 SQLQTDSE 253
+ + + E
Sbjct: 1044 EEREKEGE 1051
Score = 39.7 bits (91), Expect = 0.007
Identities = 23/68 (33%), Positives = 39/68 (57%), Gaps = 3/68 (4%)
Query: 187 GGQEQAPEHKQEQGVEHRQEPTQEHK-QEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAV 245
G +E+ +E+G +E E K +EEG++ E + EE+E EG+ E+G+G EG E
Sbjct: 895 GEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEG--EGEEEE 952
Query: 246 SQLQTDSE 253
+ + + E
Sbjct: 953 GEWEGEEE 960
Score = 39.7 bits (91), Expect = 0.007
Identities = 23/69 (33%), Positives = 39/69 (56%), Gaps = 3/69 (4%)
Query: 188 GQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEE---EQEEEGKQEEGQGTKEGREA 244
G+E E ++E+G ++ E ++EEG+ + E+EE E EEEG+ E +G EG E
Sbjct: 925 GEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEE 984
Query: 245 VSQLQTDSE 253
+ + + E
Sbjct: 985 EGEGEGEEE 993
Score = 39.3 bits (90), Expect = 0.009
Identities = 21/70 (30%), Positives = 39/70 (55%), Gaps = 3/70 (4%)
Query: 187 GGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQE---EQEEEQEEEGKQEEGQGTKEGRE 243
GG+E+ E ++E+G +E + +EEG+ +E E+E+E+ E K+E ++G E
Sbjct: 730 GGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEE 789
Query: 244 AVSQLQTDSE 253
Q + + E
Sbjct: 790 EGDQGEGEEE 799
Score = 39.3 bits (90), Expect = 0.009
Identities = 21/58 (36%), Positives = 34/58 (58%), Gaps = 2/58 (3%)
Query: 188 GQEQAPEHKQEQGVEHRQEPT--QEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGRE 243
G+E E ++E+G ++E +E +EEG + E +EEE E G+++E G EG E
Sbjct: 761 GEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGE 818
Score = 39.3 bits (90), Expect = 0.009
Identities = 22/66 (33%), Positives = 35/66 (53%)
Query: 188 GQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQ 247
G+E+ E + E G +E E + EE + + E EEE E EG++ EG+G +E E +
Sbjct: 932 GEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGE 991
Query: 248 LQTDSE 253
+ E
Sbjct: 992 EEEGEE 997
Score = 39.3 bits (90), Expect = 0.009
Identities = 25/75 (33%), Positives = 40/75 (53%), Gaps = 7/75 (9%)
Query: 188 GQEQAPEHKQEQGV-EHRQEPTQEHKQEEGQKQE------EQEEEQEEEGKQEEGQGTKE 240
G+E E ++E+G E +E +E +EEG+ +E E+EEE E EG+ E +G E
Sbjct: 974 GEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGE 1033
Query: 241 GREAVSQLQTDSEPK 255
G E + + + K
Sbjct: 1034 GEEEEGEEEGEEREK 1048
Score = 38.9 bits (89), Expect = 0.012
Identities = 22/60 (36%), Positives = 35/60 (58%), Gaps = 6/60 (10%)
Query: 188 GQEQAPEHKQEQ------GVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEG 241
G+E+ E K E+ G E +E E ++EEG+ + E+E E E E ++ EG+G +EG
Sbjct: 849 GEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEG 908
Score = 38.5 bits (88), Expect = 0.016
Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Query: 188 GQEQAPEHK-QEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGRE 243
G+E+ E K +E+G E E +E + EG+ E + EE+E E + EE +G EG E
Sbjct: 912 GEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEE 968
Score = 38.5 bits (88), Expect = 0.016
Identities = 21/58 (36%), Positives = 35/58 (60%), Gaps = 3/58 (5%)
Query: 187 GGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGK---QEEGQGTKEG 241
G +E E ++ +G +E E ++EEG+++ E+E E EEEG+ +EE +G EG
Sbjct: 966 GEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEG 1023
Score = 38.1 bits (87), Expect = 0.021
Identities = 20/70 (28%), Positives = 36/70 (51%)
Query: 190 EQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQ 249
E E +++ + R QE K+ E Q+E+ +E EE G++E G+G +E + + +
Sbjct: 691 EGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEE 750
Query: 250 TDSEPKFHSE 259
+ E K E
Sbjct: 751 KEGEGKEEGE 760
Score = 37.7 bits (86), Expect = 0.027
Identities = 24/74 (32%), Positives = 42/74 (56%), Gaps = 2/74 (2%)
Query: 188 GQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQE-EEQEEEGK-QEEGQGTKEGREAV 245
G+E+ E ++E+G +E +E + EE ++ E E EE+E EG+ +EEG+G E E
Sbjct: 842 GEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGE 901
Query: 246 SQLQTDSEPKFHSE 259
+ + + E + E
Sbjct: 902 GEGEEEGEGEGEEE 915
Score = 37.7 bits (86), Expect = 0.027
Identities = 24/69 (34%), Positives = 41/69 (59%), Gaps = 3/69 (4%)
Query: 188 GQEQAPEHK-QEQGVEHRQEPTQEHKQEEGQKQEEQE-EEQEEEGK-QEEGQGTKEGREA 244
G+E+ E + +E+G E E +E + EG+++ E E EE+E EG+ +EEG+G E E
Sbjct: 858 GEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEG 917
Query: 245 VSQLQTDSE 253
+ + + E
Sbjct: 918 EGKGEEEGE 926
Score = 37.7 bits (86), Expect = 0.027
Identities = 20/72 (27%), Positives = 38/72 (52%)
Query: 188 GQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQ 247
G+E+ +E+ E + E E + EG+++E + E ++ EG+ EE +G EG E +
Sbjct: 904 GEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGE 963
Query: 248 LQTDSEPKFHSE 259
+ + E + E
Sbjct: 964 GEGEEEGEGEGE 975
Score = 37.7 bits (86), Expect = 0.027
Identities = 22/88 (25%), Positives = 40/88 (45%), Gaps = 10/88 (11%)
Query: 187 GGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEE----------QEEEQEEEGKQEEGQ 236
G +E+ E +E+G + + ++EEG+ + E +EEE EEEG++ E +
Sbjct: 990 GEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKE 1049
Query: 237 GTKEGREAVSQLQTDSEPKFHSESLSSN 264
G E + + + E K+ N
Sbjct: 1050 GEGEENRRNREEEEEEEGKYQETGEEEN 1077
Score = 37.7 bits (86), Expect = 0.027
Identities = 20/84 (23%), Positives = 45/84 (53%), Gaps = 8/84 (9%)
Query: 188 GQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQE--------EEGKQEEGQGTK 239
G+E E ++E+G E +E +E + EE ++ E+EEE+E EE ++++G+ K
Sbjct: 1027 GEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYK 1086
Query: 240 EGREAVSQLQTDSEPKFHSESLSS 263
+ + ++ + +S+++
Sbjct: 1087 KVSKIKGSVKYGKHKTYQKKSVTN 1110
Score = 37.4 bits (85), Expect = 0.035
Identities = 20/56 (35%), Positives = 34/56 (60%), Gaps = 2/56 (3%)
Query: 188 GQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGRE 243
G+E+ E + E+ E + +E + EG++ E + EE+E EG+ EE +G +EG E
Sbjct: 948 GEEEEGEWEGEE--EEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEE 1001
Score = 36.6 bits (83), Expect = 0.060
Identities = 20/57 (35%), Positives = 33/57 (57%), Gaps = 3/57 (5%)
Query: 188 GQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGK---QEEGQGTKEG 241
G+ + E + E E E E + EG+++E + E +EEEG+ +EEG+G +EG
Sbjct: 953 GEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEG 1009
Score = 36.2 bits (82), Expect = 0.079
Identities = 19/56 (33%), Positives = 31/56 (55%)
Query: 188 GQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGRE 243
G+ + E + +G E E E + E ++EE E + EEEG++ EG+G +E E
Sbjct: 883 GEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGE 938
Score = 35.8 bits (81), Expect = 0.10
Identities = 21/67 (31%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Query: 188 GQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQE-EQEEEQEEEGKQEEGQGTKEGREAVS 246
G+E+ E + E E + +E + EG+++E E E E+E EG+ EE +G +G E
Sbjct: 867 GEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGE 926
Query: 247 QLQTDSE 253
+ + + E
Sbjct: 927 EGEGEGE 933
Score = 35.4 bits (80), Expect = 0.13
Identities = 19/57 (33%), Positives = 31/57 (54%)
Query: 187 GGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGRE 243
G +E+ +E+G +E E + EE + E +EEE E +G++E +G EG E
Sbjct: 878 GEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEE 934
Score = 35.4 bits (80), Expect = 0.13
Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 3/55 (5%)
Query: 187 GGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEG 241
G E+ E + +G E E E + EG+++E + E +EEEG EG+G +EG
Sbjct: 919 GKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEG---EGEGEEEG 970
Score = 35.0 bits (79), Expect = 0.18
Identities = 22/58 (37%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Query: 187 GGQEQAPEHKQEQGV-EHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGRE 243
G +E E ++E+G E +E E ++EEG+ + E+E E E EG+ EE +G EG +
Sbjct: 887 GEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGE-EGEGEGEEEEGEGEGED 943
Score = 35.0 bits (79), Expect = 0.18
Identities = 22/60 (36%), Positives = 32/60 (53%), Gaps = 3/60 (5%)
Query: 187 GGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEE---EQEEEGKQEEGQGTKEGRE 243
G +E+ +E+ E E E + EEG+ + E+EE E EEE +EEG+ EG E
Sbjct: 948 GEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEE 1007
Score = 34.7 bits (78), Expect = 0.23
Identities = 15/62 (24%), Positives = 39/62 (62%), Gaps = 1/62 (1%)
Query: 188 GQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQ 247
G+E+ E ++ +G ++E ++ ++ G++++ +EE + EG++EE +G E +E +
Sbjct: 755 GKEEG-EGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGE 813
Query: 248 LQ 249
++
Sbjct: 814 VE 815
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 44.3 bits (103), Expect = 3e-04
Identities = 33/109 (30%), Positives = 54/109 (49%), Gaps = 4/109 (3%)
Query: 170 ERLSNNVEELLQSSLSLGGQEQAPE-HKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEE 228
+R +EE+ Q L+ G + E + EQ E R++P ++E + +EE+EE+QE+
Sbjct: 537 KREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQP---QIKQEPESEEEEEEKQEK 593
Query: 229 EGKQEEGQGTKEGREAVSQLQTDSEPKFHSESLSSNPSSFAPRVREVES 277
E K+EE +E E L+ P + S+SS + P ES
Sbjct: 594 EEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPGDES 642
Score = 34.3 bits (77), Expect = 0.30
Identities = 32/137 (23%), Positives = 66/137 (48%), Gaps = 9/137 (6%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQE-EGQKQEEQEEEQEEE-----GKQEEGQGTKEGR 242
+E++ + ++E+ E +E +E ++E E +++ E+E E+E E ++E+ + E R
Sbjct: 385 REKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERR 444
Query: 243 EAVSQLQTDSEPKFHSESLSSNPSSFAPRVREVE-STPMIMENIQELIRSAQEIDEMNEI 301
+ +L+ + + E L + + RE E E +E+ + A+ + E E
Sbjct: 445 KLERKLR--EKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLED 502
Query: 302 YDENSYWRNQNPGSLLQ 318
YD++ GS LQ
Sbjct: 503 YDDDRDDPKYYRGSALQ 519
Score = 32.7 bits (73), Expect = 0.87
Identities = 15/56 (26%), Positives = 35/56 (62%), Gaps = 1/56 (1%)
Query: 189 QEQAPEHKQEQGVE-HRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGRE 243
+E+ + K+ Q +E R+E +E ++E +++ E+E E+E E ++E+ + + R+
Sbjct: 293 EEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERD 348
Score = 32.0 bits (71), Expect = 1.5
Identities = 14/67 (20%), Positives = 36/67 (53%)
Query: 187 GGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVS 246
G +E+ + +++ E +E +E ++ E +++ E+E E+E+E ++E + R+
Sbjct: 296 GKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTK 355
Query: 247 QLQTDSE 253
+ D +
Sbjct: 356 ERDRDRD 362
Score = 30.4 bits (67), Expect = 4.3
Identities = 15/65 (23%), Positives = 32/65 (49%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQL 248
+E+ K+ + E +E +E ++ E +++ E+E E+E+E ++E + R
Sbjct: 300 KERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDR 359
Query: 249 QTDSE 253
D E
Sbjct: 360 DRDRE 364
Score = 29.6 bits (65), Expect = 7.4
Identities = 12/47 (25%), Positives = 27/47 (57%)
Query: 194 EHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKE 240
E ++ + + RQE +E ++ E +++ E+E + E ++ E + KE
Sbjct: 292 EEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKE 338
Score = 29.6 bits (65), Expect = 7.4
Identities = 13/60 (21%), Positives = 30/60 (50%)
Query: 194 EHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQLQTDSE 253
E ++E+ E R+ + ++ E +K++E+E E+E + ++ + R+ D E
Sbjct: 313 ERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRE 372
Score = 29.3 bits (64), Expect = 9.6
Identities = 19/93 (20%), Positives = 44/93 (47%), Gaps = 5/93 (5%)
Query: 189 QEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEGREAVSQL 248
+++ E ++E+ E + + ++ E ++++E+E E+E E ++ + + R+ +
Sbjct: 306 EKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRER 365
Query: 249 QTDSEPKFHSE-----SLSSNPSSFAPRVREVE 276
D + + S+ S S S R RE E
Sbjct: 366 DRDRDRERSSDRNKDRSRSREKSRDRERERERE 398
>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
Length = 740
Score = 44.3 bits (103), Expect = 3e-04
Identities = 24/95 (25%), Positives = 47/95 (49%), Gaps = 1/95 (1%)
Query: 190 EQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQEEGQGTKEG-REAVSQL 248
E++ E ++E+ E +E T ++E+ ++ +E +E+ EEE ++EE K+G + +S L
Sbjct: 441 EESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSL 500
Query: 249 QTDSEPKFHSESLSSNPSSFAPRVREVESTPMIME 283
Q +E S S + S ++ E
Sbjct: 501 QISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSE 535
Score = 33.9 bits (76), Expect = 0.39
Identities = 25/122 (20%), Positives = 52/122 (42%), Gaps = 3/122 (2%)
Query: 173 SNNVEELLQSSLSLGGQEQAPEHKQEQGVEHRQEPTQEHKQEEGQKQEEQEEEQEEEGKQ 232
S++ + ++SL G + P QG + + +E +EE+EEE+EEE +
Sbjct: 402 SSHSADTPEASLDSG---EGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEA 458
Query: 233 EEGQGTKEGREAVSQLQTDSEPKFHSESLSSNPSSFAPRVREVESTPMIMENIQELIRSA 292
+ + ++ + + D E E+ + +P S +E +++ RS+
Sbjct: 459 TDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSS 518
Query: 293 QE 294
E
Sbjct: 519 GE 520
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.130 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,518,293
Number of Sequences: 37866
Number of extensions: 1187741
Number of successful extensions: 29381
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 588
Number of HSP's successfully gapped in prelim test: 522
Number of HSP's that attempted gapping in prelim test: 11374
Number of HSP's gapped (non-prelim): 7630
length of query: 543
length of database: 18,247,518
effective HSP length: 107
effective length of query: 436
effective length of database: 14,195,856
effective search space: 6189393216
effective search space used: 6189393216
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.