Search of human proteins with 17999520

Search of human proteins with 17999520

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|17999520 solute carrier family 32, member 1 [Homo sapiens]
         (525 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|17999520 solute carrier family 32, member 1 [Homo sapiens]        1063   0.0  
gi|222418631 solute carrier family 36, member 2 [Homo sapiens]         90   6e-18
gi|41352721 solute carrier family 36 member 1 [Homo sapiens]           78   2e-14
gi|193788624 solute carrier family 38, member 5 [Homo sapiens]         69   8e-12
gi|222446642 solute carrier family 36, member 3 isoform 1 [Homo ...    67   4e-11
gi|222446640 solute carrier family 36, member 3 isoform 2 [Homo ...    67   4e-11
gi|40807351 solute carrier family 36 (proton/amino acid symporte...    64   3e-10
gi|117168277 amino acid transporter system A1 [Homo sapiens]           64   3e-10
gi|117168275 amino acid transporter system A1 [Homo sapiens]           64   3e-10
gi|83921602 solute carrier family 38, member 10 isoform a [Homo ...    63   6e-10
gi|20070376 solute carrier family 38, member 10 isoform b [Homo ...    63   6e-10
gi|24429574 solute carrier family 38, member 6 [Homo sapiens]          61   2e-09
gi|21361602 solute carrier family 38, member 2 [Homo sapiens]          55   1e-07
gi|122937281 solute carrier family 38, member 8 [Homo sapiens]         49   1e-05
gi|222418629 solute carrier family 38, member 9 [Homo sapiens]         48   3e-05
gi|5870893 solute carrier family 38, member 3 [Homo sapiens]           46   7e-05
gi|219689132 solute carrier family 38, member 4 [Homo sapiens]         45   1e-04
gi|18482385 solute carrier family 38, member 4 [Homo sapiens]          45   1e-04
gi|8922692 solute carrier family 38, member 7 [Homo sapiens]           38   0.020
gi|112382239 desmuslin isoform B [Homo sapiens]                        31   2.4  
gi|112382237 desmuslin isoform A [Homo sapiens]                        31   2.4  
gi|44662807 hypothetical protein LOC388407 [Homo sapiens]              31   2.4  
gi|84662753 G protein-coupled receptor 149 [Homo sapiens]              31   3.2  
gi|119829187 alpha 1 type XVII collagen [Homo sapiens]                 30   5.4  
gi|153792144 ATP-binding cassette, sub-family A, member 10 [Homo...    30   7.1  
gi|238231392 dedicator of cytokinesis 8 [Homo sapiens]                 29   9.2  
gi|157388943 transmembrane protein 104 [Homo sapiens]                  29   9.2  

>gi|17999520 solute carrier family 32, member 1 [Homo sapiens]
          Length = 525

 Score = 1063 bits (2750), Expect = 0.0
 Identities = 525/525 (100%), Positives = 525/525 (100%)

Query: 1   MATLLRSKLSNVATSVSNKSQAKMSGMFARMGFQAATDEEAVGFAHCDDLDFEHRQGLQM 60
           MATLLRSKLSNVATSVSNKSQAKMSGMFARMGFQAATDEEAVGFAHCDDLDFEHRQGLQM
Sbjct: 1   MATLLRSKLSNVATSVSNKSQAKMSGMFARMGFQAATDEEAVGFAHCDDLDFEHRQGLQM 60

Query: 61  DILKAEGEPCGDEGAEAPVEGDIHYQRGSGAPLPPSGSKDQVGGGGEFGGHDKPKITAWE 120
           DILKAEGEPCGDEGAEAPVEGDIHYQRGSGAPLPPSGSKDQVGGGGEFGGHDKPKITAWE
Sbjct: 61  DILKAEGEPCGDEGAEAPVEGDIHYQRGSGAPLPPSGSKDQVGGGGEFGGHDKPKITAWE 120

Query: 121 AGWNVTNAIQGMFVLGLPYAILHGGYLGLFLIIFAAVVCCYTGKILIACLYEENEDGEVV 180
           AGWNVTNAIQGMFVLGLPYAILHGGYLGLFLIIFAAVVCCYTGKILIACLYEENEDGEVV
Sbjct: 121 AGWNVTNAIQGMFVLGLPYAILHGGYLGLFLIIFAAVVCCYTGKILIACLYEENEDGEVV 180

Query: 181 RVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLPVSQ 240
           RVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLPVSQ
Sbjct: 181 RVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLPVSQ 240

Query: 241 KSWSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFY 300
           KSWSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFY
Sbjct: 241 KSWSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFY 300

Query: 301 IDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYL 360
           IDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYL
Sbjct: 301 IDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYL 360

Query: 361 TWADETKEVITDNLPGSIRAVVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPA 420
           TWADETKEVITDNLPGSIRAVVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPA
Sbjct: 361 TWADETKEVITDNLPGSIRAVVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPA 420

Query: 421 CYSGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRL 480
           CYSGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRL
Sbjct: 421 CYSGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRL 480

Query: 481 LWRKLLWHQVFFDVAIFVIGGICSVSGFVHSLEGLIEAYRTNAED 525
           LWRKLLWHQVFFDVAIFVIGGICSVSGFVHSLEGLIEAYRTNAED
Sbjct: 481 LWRKLLWHQVFFDVAIFVIGGICSVSGFVHSLEGLIEAYRTNAED 525


>gi|222418631 solute carrier family 36, member 2 [Homo sapiens]
          Length = 483

 Score = 89.7 bits (221), Expect = 6e-18
 Identities = 94/439 (21%), Positives = 184/439 (41%), Gaps = 40/439 (9%)

Query: 107 EFGGHDKPK-ITAWEAGWNVTNAIQGMFVLGLPYAILHGGYL-GLFLIIFAAVVCCYTGK 164
           E  G  K K IT ++A  ++     G  +LGLP A+ + G L G   ++    + C+   
Sbjct: 44  ESAGLKKTKGITVFQALIHLVKGNMGTGILGLPLAVKNAGILMGPLSLLVMGFIACHCMH 103

Query: 165 ILIACLYE--ENEDGEVVRVRDSYVAIANA---CCAPRFPTLGGRVVNVAQIIELVMTCI 219
           IL+ C     +  +   +   D+ +    A            G  +V+   II  +  C 
Sbjct: 104 ILVKCAQRFCKRLNKPFMDYGDTVMHGLEANPNAWLQNHAHWGRHIVSFFLIITQLGFCC 163

Query: 220 LYVVVSGNLMYNSFPGLPVSQKSWSIIATAVLLPC-----------------AFLKNLKA 262
           +Y+V   + +      +  +  +     T +L P                    ++NL+ 
Sbjct: 164 VYIVFLADNLKQVVEAVNSTTNNCYSNETVILTPTMDSRLYMLSFLPFLVLLVLIRNLRI 223

Query: 263 VSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIF 322
           ++ FS+L  ++  V  +++I Y      D +  ++      K +P+  G  +FS+ S   
Sbjct: 224 LTIFSMLANISMLVSLVIIIQYITQEIPDPS--RLPLVASWKTYPLFFGTAIFSFESIGV 281

Query: 323 LPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYLTWADETKEVITDNLPGS-IRAV 381
           +  LE  M+    F  +++        L    A + YL + D+ K  I+ NLP   +   
Sbjct: 282 VLPLENKMKNARHFPAILSLGMSIVTSLYIGMAALGYLRFGDDIKASISLNLPNCWLYQS 341

Query: 382 VNIFLVAKALLSYPLPFFAAVEVLEK-SLFQEGSRAFFPACYSGDGRLKSWGLTLRCALV 440
           V +  +A  L +Y L F+   E++   ++ +  +R   P             L++R  +V
Sbjct: 342 VKLLYIAGILCTYALQFYVPAEIIIPFAISRVSTRWALPL-----------DLSIRLVMV 390

Query: 441 VFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLLWRK-LLWHQVFFDVAIFVI 499
             T L+AI +P   L++ L GS++G  L  ++P L  +   + + +    +F D  I ++
Sbjct: 391 CLTCLLAILIPRLDLVISLVGSVSGTALALIIPPLLEVTTFYSEGMSPLTIFKDALISIL 450

Query: 500 GGICSVSGFVHSLEGLIEA 518
           G +  V G   +L+ L+++
Sbjct: 451 GFVGFVVGTYQALDELLKS 469


>gi|41352721 solute carrier family 36 member 1 [Homo sapiens]
          Length = 476

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 97/451 (21%), Positives = 186/451 (41%), Gaps = 42/451 (9%)

Query: 95  PSGSKDQVGGGGEFGGHDKPKITAW-EAGWNVTNAIQGMFVLGLPYAILHGGY-LGLFLI 152
           PS   + +   G +    +   T W +   ++     G  +LGLP A+ + G  +G   +
Sbjct: 25  PSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGIVMGPISL 84

Query: 153 IFAAVVCCYTGKILIACLYE--ENEDGEVVRVRDSYV-AIANACCA--PRFPTLGGRVVN 207
           +   +V  +   IL+ C +      +   V   D+ +  + ++ C+        G RVV+
Sbjct: 85  LIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTVMYGLESSPCSWLRNHAHWGRRVVD 144

Query: 208 VAQII-ELVMTCILYVVVSGNLM-------------YNS-----FPGLPVSQKSWSIIAT 248
              I+ +L   C+ +V ++ N               +N+      P +       S +  
Sbjct: 145 FFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNETVILTPTMDSRLYMLSFLPF 204

Query: 249 AVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFYIDVKKFPI 308
            VLL   F++NL+A+S FSLL  +   V  +++  + + R  D +   +      K +P+
Sbjct: 205 LVLL--VFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIPDPS--HLPLVAPWKTYPL 260

Query: 309 SIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYLTWADETKE 368
             G  +FS+     +  LE  M+ P +F  ++    +   +L      + YL +    + 
Sbjct: 261 FFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVTILYISLGCLGYLQFGANIQG 320

Query: 369 VITDNLPGS-IRAVVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYSGDGR 427
            IT NLP   +   V +        +Y L F+   E++           FF +       
Sbjct: 321 SITLNLPNCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIP---------FFVSRAPEHCE 371

Query: 428 LKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLLWRK-LL 486
           L    L +R  LV  T ++AI +P   L++ L GS++ + L  ++P L  +   + + + 
Sbjct: 372 LVV-DLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTTFYSEGMS 430

Query: 487 WHQVFFDVAIFVIGGICSVSGFVHSLEGLIE 517
              +F D  I ++G +  V G   +L  LI+
Sbjct: 431 PLTIFKDALISILGFVGFVVGTYEALYELIQ 461


>gi|193788624 solute carrier family 38, member 5 [Homo sapiens]
          Length = 472

 Score = 69.3 bits (168), Expect = 8e-12
 Identities = 88/402 (21%), Positives = 168/402 (41%), Gaps = 74/402 (18%)

Query: 123 WNVTNAIQGMFVLGLPYAILHGGYLG-LFLIIFAAVVCCYTGKILIACL-------YEEN 174
           +N++NAI G  +LGL YA+ H G +  L L++  A++  Y+  +L+ C        YE+ 
Sbjct: 55  FNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCAGIAGIRAYEQL 114

Query: 175 EDGEVVRVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYV------VVSGNL 228
             G+        V +A   C      +   +  +   + LV+   LY+       + GNL
Sbjct: 115 --GQRAFGPAGKVVVATVICLHNVGAMSSYLFIIKSELPLVIGTFLYMDPEGDWFLKGNL 172

Query: 229 MYNSFPGLPVSQKSWSIIATAVLLPCAFLKNLKAV---SKFSLLCTLAHFVINILVIAYC 285
           +               I++  ++LP A +K+L  +   S  SL C L  F+++++   + 
Sbjct: 173 LI-------------IIVSVLIILPLALMKHLGYLGYTSGLSLTCML-FFLVSVIYKKFQ 218

Query: 286 L--------------------SRARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPS 325
           L                    S+  + + E   F +D  +   ++ I+ F++     +  
Sbjct: 219 LGCAIGHNETAMESEALVGLPSQGLNSSCEAQMFTVD-SQMSYTVPIMAFAFVCHPEVLP 277

Query: 326 LEGNMQQPSE--FHCMMNWTHIAACVLKGLFALVAYLTWADETKEVITD--NLPGSIRAV 381
           +   + +PS+     + N +  A   + GL A   YLT+    K  +    +    +   
Sbjct: 278 IYTELCRPSKRRMQAVANVSIGAMFCMYGLTATFGYLTFYSSVKAEMLHMYSQKDPLILC 337

Query: 382 VNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYSGDGRLKSWGLTLRCALVV 441
           V + ++    L+ P+  F     L++ LF               G+  SW   +  AL++
Sbjct: 338 VRLAVLLAVTLTVPVVLFPIRRALQQLLFP--------------GKAFSWPRHVAIALIL 383

Query: 442 FTLL--MAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLL 481
             L+  + I VP    + G+ GS +   L F+LPS+F+LR++
Sbjct: 384 LVLVNVLVICVPTIRDIFGVIGSTSAPSLIFILPSIFYLRIV 425


>gi|222446642 solute carrier family 36, member 3 isoform 1 [Homo
           sapiens]
          Length = 511

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 58/276 (21%), Positives = 117/276 (42%), Gaps = 22/276 (7%)

Query: 243 WSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFYID 302
           + +I    L+   F++NLK +S FS L  +       L+  Y +      +   +    +
Sbjct: 233 YMLIILPFLILLVFIQNLKVLSVFSTLANITTLGSMALIFEYIMEGIPYPS--NLPLMAN 290

Query: 303 VKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYLTW 362
            K F +  G  +F++     +  L+  M+ P +F  ++        +L  L   + Y+ +
Sbjct: 291 WKTFLLFFGTAIFTFEGVGMVLPLKNQMKHPQQFSFVLYLGMSIVIILYILLGTLGYMKF 350

Query: 363 ADETKEVITDNLPGS-IRAVVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPAC 421
             +T+  IT NLP   +   V +        +Y L F    E++      + S       
Sbjct: 351 GSDTQASITLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPFAISQVS------- 403

Query: 422 YSGDGRLKSWGL----TLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFH 477
                  +SW L    ++R ALV  T + AI +P   L++ L GS++ + L  ++P+L  
Sbjct: 404 -------ESWALFVDLSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALLE 456

Query: 478 LRLLWRK-LLWHQVFFDVAIFVIGGICSVSGFVHSL 512
           + + + + +    +  D+ I ++G +  + G   +L
Sbjct: 457 IVIFYSEDMSCVTIAKDIMISIVGLLGCIFGTYQAL 492


>gi|222446640 solute carrier family 36, member 3 isoform 2 [Homo
           sapiens]
          Length = 470

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 58/276 (21%), Positives = 117/276 (42%), Gaps = 22/276 (7%)

Query: 243 WSIIATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFYID 302
           + +I    L+   F++NLK +S FS L  +       L+  Y +      +   +    +
Sbjct: 192 YMLIILPFLILLVFIQNLKVLSVFSTLANITTLGSMALIFEYIMEGIPYPS--NLPLMAN 249

Query: 303 VKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYLTW 362
            K F +  G  +F++     +  L+  M+ P +F  ++        +L  L   + Y+ +
Sbjct: 250 WKTFLLFFGTAIFTFEGVGMVLPLKNQMKHPQQFSFVLYLGMSIVIILYILLGTLGYMKF 309

Query: 363 ADETKEVITDNLPGS-IRAVVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPAC 421
             +T+  IT NLP   +   V +        +Y L F    E++      + S       
Sbjct: 310 GSDTQASITLNLPNCWLYQSVKLMYSIGIFFTYALQFHVPAEIIIPFAISQVS------- 362

Query: 422 YSGDGRLKSWGL----TLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFH 477
                  +SW L    ++R ALV  T + AI +P   L++ L GS++ + L  ++P+L  
Sbjct: 363 -------ESWALFVDLSVRSALVCLTCVSAILIPRLDLVISLVGSVSSSALALIIPALLE 415

Query: 478 LRLLWRK-LLWHQVFFDVAIFVIGGICSVSGFVHSL 512
           + + + + +    +  D+ I ++G +  + G   +L
Sbjct: 416 IVIFYSEDMSCVTIAKDIMISIVGLLGCIFGTYQAL 451


>gi|40807351 solute carrier family 36 (proton/amino acid symporter),
           member 4 [Homo sapiens]
          Length = 504

 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 79/377 (20%), Positives = 147/377 (38%), Gaps = 42/377 (11%)

Query: 131 GMFVLGLPYAILHGGY-LGLFLIIFAAVVCCYTGKILIACL------YEENEDGEVVRVR 183
           G  +LGLP AI + G  LG   ++F  ++  +   IL+ C       ++++  G    V 
Sbjct: 74  GTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCLRFKKSTLGYSDTVS 133

Query: 184 DSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGL------- 236
            + + ++   C  +    G  VV+   +I  +  C +Y+V     +     G        
Sbjct: 134 FA-MEVSPWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQVHEGFLESKVFI 192

Query: 237 --------PVSQKSWSI-IATAVLLP----CAFLKNLKAVSKFSLLCTLAHFVINILVIA 283
                   P  ++S  + I     LP      F++ LK +   S L  ++  V  +++  
Sbjct: 193 SNSTNSSNPCERRSVDLRIYMLCFLPFIILLVFIRELKNLFVLSFLANVSMAVSLVIIYQ 252

Query: 284 YCLSRARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWT 343
           Y +    D     +      KK+P+  G  VF++     +  LE  M++   F   +N  
Sbjct: 253 YVVRNMPDP--HNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKESKRFPQALNIG 310

Query: 344 HIAACVLKGLFALVAYLTWADETKEVITDNLPGSI--RAVVNIFLVAKALLSYPLPFFAA 401
                 L    A + Y+ + DE K  IT NLP  +     V I       ++Y + F+  
Sbjct: 311 MGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIFVTYSIQFYVP 370

Query: 402 VEVLEKSLFQEGSRAFFPACYSGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTG 461
            E++   +  +    +   C  G          +R  LV  T   AI +P   +++   G
Sbjct: 371 AEIIIPGITSKFHTKWKQICEFG----------IRSFLVSITCAGAILIPRLDIVISFVG 420

Query: 462 SLTGAGLCFLLPSLFHL 478
           +++ + L  +LP L  +
Sbjct: 421 AVSSSTLALILPPLVEI 437


>gi|117168277 amino acid transporter system A1 [Homo sapiens]
          Length = 487

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 86/394 (21%), Positives = 164/394 (41%), Gaps = 66/394 (16%)

Query: 123 WNVTNAIQGMFVLGLPYAILHGGYLGLFLIIFAAV--VCCYTGKILIACLYEENEDGEVV 180
           +N++NAI G  +LGL +A+ + G L LFL++  +V  +  Y+  +L+ C     E G +V
Sbjct: 78  FNLSNAIMGSGILGLAFALANTGIL-LFLVLLTSVTLLSIYSINLLLIC---SKETGCMV 133

Query: 181 RVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLPVSQ 240
                Y  +        F T G  V+  A  ++     + Y+ +  N + ++   L   +
Sbjct: 134 -----YEKLGEQV----FGTTGKFVIFGATSLQNTGAMLSYLFIVKNELPSAIKFLMGKE 184

Query: 241 KSWS-----------IIATAVLLPCAFLKNLKAV---SKFSLLCTLAHFVINILVIAY-- 284
           +++S           I+   ++LP   LKNL  +   S FSL C     V  ++V+ Y  
Sbjct: 185 ETFSAWYVDGRVLVVIVTFGIILPLCLLKNLGYLGYTSGFSLSC----MVFFLIVVIYKK 240

Query: 285 ----CL---------SRARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQ 331
               C+         + + +      K+     K   ++  I F++     +  +   ++
Sbjct: 241 FQIPCIVPELNSTISANSTNADTCTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSELK 300

Query: 332 QPSEFHCMM--NWTHIAACVLKGLFALVAYLTWADETKEVITDNLPGS---IRAVVNIFL 386
             S+    M  N +  A  V+  L A+  YLT+ D  +  +          +   V + +
Sbjct: 301 DRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYDNVQSDLLHKYQSKDDILILTVRLAV 360

Query: 387 VAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYSGDGRLKSWGLTLRCALVVFTLLM 446
           +   +L+ P+ FF     +  SLF+   +  F  C             + C L+V   L+
Sbjct: 361 IVAVILTVPVLFFT----VRSSLFELAKKTKFNLCRH---------TVVTCILLVVINLL 407

Query: 447 AIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRL 480
            I++P    + G+ G  +   L F+LPS  +L++
Sbjct: 408 VIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKI 441


>gi|117168275 amino acid transporter system A1 [Homo sapiens]
          Length = 487

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 86/394 (21%), Positives = 164/394 (41%), Gaps = 66/394 (16%)

Query: 123 WNVTNAIQGMFVLGLPYAILHGGYLGLFLIIFAAV--VCCYTGKILIACLYEENEDGEVV 180
           +N++NAI G  +LGL +A+ + G L LFL++  +V  +  Y+  +L+ C     E G +V
Sbjct: 78  FNLSNAIMGSGILGLAFALANTGIL-LFLVLLTSVTLLSIYSINLLLIC---SKETGCMV 133

Query: 181 RVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLPVSQ 240
                Y  +        F T G  V+  A  ++     + Y+ +  N + ++   L   +
Sbjct: 134 -----YEKLGEQV----FGTTGKFVIFGATSLQNTGAMLSYLFIVKNELPSAIKFLMGKE 184

Query: 241 KSWS-----------IIATAVLLPCAFLKNLKAV---SKFSLLCTLAHFVINILVIAY-- 284
           +++S           I+   ++LP   LKNL  +   S FSL C     V  ++V+ Y  
Sbjct: 185 ETFSAWYVDGRVLVVIVTFGIILPLCLLKNLGYLGYTSGFSLSC----MVFFLIVVIYKK 240

Query: 285 ----CL---------SRARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQ 331
               C+         + + +      K+     K   ++  I F++     +  +   ++
Sbjct: 241 FQIPCIVPELNSTISANSTNADTCTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSELK 300

Query: 332 QPSEFHCMM--NWTHIAACVLKGLFALVAYLTWADETKEVITDNLPGS---IRAVVNIFL 386
             S+    M  N +  A  V+  L A+  YLT+ D  +  +          +   V + +
Sbjct: 301 DRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYDNVQSDLLHKYQSKDDILILTVRLAV 360

Query: 387 VAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYSGDGRLKSWGLTLRCALVVFTLLM 446
           +   +L+ P+ FF     +  SLF+   +  F  C             + C L+V   L+
Sbjct: 361 IVAVILTVPVLFFT----VRSSLFELAKKTKFNLCRH---------TVVTCILLVVINLL 407

Query: 447 AIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRL 480
            I++P    + G+ G  +   L F+LPS  +L++
Sbjct: 408 VIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKI 441


>gi|83921602 solute carrier family 38, member 10 isoform a [Homo
           sapiens]
          Length = 1119

 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 89/442 (20%), Positives = 185/442 (41%), Gaps = 53/442 (11%)

Query: 119 WEAGWNVTNAIQGMFVLGLPYAILHGGY-LGLFLIIFAAVVCCYTGKILIACLYEENEDG 177
           W    N+ N+I G+ VL +P+     G  LG  L++F + +   +   L+          
Sbjct: 9   WGLITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVK--------S 60

Query: 178 EVVRVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLP 237
             +  R +Y  +A       +   G  +V  + I  ++ TCI + VV G+L  N F  L 
Sbjct: 61  ASLSKRRTYAGLAFHA----YGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLF 116

Query: 238 VSQKSWSI-------IATAVLLPCAFLKNLKA-VSKFSLLCTLAHFVINILVIAYCLSRA 289
             Q   +        ++  ++LP +  +N+ A +  FS +  L + V   +++   L   
Sbjct: 117 GFQVGGTFRMFLLFAVSLCIVLPLSLQRNMMASIQSFSAMALLFYTVFMFVIVLSSLKHG 176

Query: 290 R-DWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAAC 348
                W +   Y+  +     I I   S+  Q  +     ++ +PS    M +    +  
Sbjct: 177 LFSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPS-VKTMSSIFASSLN 235

Query: 349 VLKGLFALVA---YLTWADETKEVITDNLPGS-IRAVVNIFLVAKALLSYPLPFFAAVEV 404
           V+   + +V    Y+++ + T   +  + P + +  ++ +  +    + +P+      + 
Sbjct: 236 VVTTFYVMVGFFGYVSFTEATAGNVLMHFPSNLVTEMLRVGFMMSVAVGFPMMILPCRQA 295

Query: 405 LEKSLFQEGSR--AFFPACYSGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGS 462
           L   L ++  +   F    Y    R K+    L  ++V  T++  I +P+   ++GLTG+
Sbjct: 296 LSTLLCEQQQKDGTFAAGGYMPPLRFKA----LTLSVVFGTMVGGILIPNVETILGLTGA 351

Query: 463 LTGAGLCFLLPSLFHLRLLWRKLLWHQV--FFDVAIFVIGGICSVS-------------- 506
             G+ +CF+ P+L + + + +  L  QV  +  + + V+  + ++S              
Sbjct: 352 TMGSLICFICPALIY-KKIHKNALSSQVVLWVGLGVLVVSTVTTLSVSEEVPEDLAEEAP 410

Query: 507 -GFVHSLEGL--IEAYRTNAED 525
            G +   EGL  +EA R +A+D
Sbjct: 411 GGRLGEAEGLMKVEAARLSAQD 432


>gi|20070376 solute carrier family 38, member 10 isoform b [Homo
           sapiens]
          Length = 780

 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 89/442 (20%), Positives = 185/442 (41%), Gaps = 53/442 (11%)

Query: 119 WEAGWNVTNAIQGMFVLGLPYAILHGGY-LGLFLIIFAAVVCCYTGKILIACLYEENEDG 177
           W    N+ N+I G+ VL +P+     G  LG  L++F + +   +   L+          
Sbjct: 9   WGLITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVK--------S 60

Query: 178 EVVRVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGLP 237
             +  R +Y  +A       +   G  +V  + I  ++ TCI + VV G+L  N F  L 
Sbjct: 61  ASLSKRRTYAGLAFHA----YGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLF 116

Query: 238 VSQKSWSI-------IATAVLLPCAFLKNLKA-VSKFSLLCTLAHFVINILVIAYCLSRA 289
             Q   +        ++  ++LP +  +N+ A +  FS +  L + V   +++   L   
Sbjct: 117 GFQVGGTFRMFLLFAVSLCIVLPLSLQRNMMASIQSFSAMALLFYTVFMFVIVLSSLKHG 176

Query: 290 R-DWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAAC 348
                W +   Y+  +     I I   S+  Q  +     ++ +PS    M +    +  
Sbjct: 177 LFSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPS-VKTMSSIFASSLN 235

Query: 349 VLKGLFALVA---YLTWADETKEVITDNLPGS-IRAVVNIFLVAKALLSYPLPFFAAVEV 404
           V+   + +V    Y+++ + T   +  + P + +  ++ +  +    + +P+      + 
Sbjct: 236 VVTTFYVMVGFFGYVSFTEATAGNVLMHFPSNLVTEMLRVGFMMSVAVGFPMMILPCRQA 295

Query: 405 LEKSLFQEGSR--AFFPACYSGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGS 462
           L   L ++  +   F    Y    R K+    L  ++V  T++  I +P+   ++GLTG+
Sbjct: 296 LSTLLCEQQQKDGTFAAGGYMPPLRFKA----LTLSVVFGTMVGGILIPNVETILGLTGA 351

Query: 463 LTGAGLCFLLPSLFHLRLLWRKLLWHQV--FFDVAIFVIGGICSVS-------------- 506
             G+ +CF+ P+L + + + +  L  QV  +  + + V+  + ++S              
Sbjct: 352 TMGSLICFICPALIY-KKIHKNALSSQVVLWVGLGVLVVSTVTTLSVSEEVPEDLAEEAP 410

Query: 507 -GFVHSLEGL--IEAYRTNAED 525
            G +   EGL  +EA R +A+D
Sbjct: 411 GGRLGEAEGLMKVEAARLSAQD 432


>gi|24429574 solute carrier family 38, member 6 [Homo sapiens]
          Length = 456

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 90/403 (22%), Positives = 166/403 (41%), Gaps = 65/403 (16%)

Query: 123 WNVTNAIQGMFVLGLPYAILHGGYLGL-FLIIFAAVVCCYTGKILIACLYE----ENED- 176
           +N+ NAI G  +LGL Y + + G  G  FL++  A++  Y+  +L++   +      ED 
Sbjct: 52  FNLMNAIMGSGILGLAYVMANTGVFGFSFLLLTVALLASYSVHLLLSMCIQTAVTSYEDL 111

Query: 177 GEVVRVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSFPGL 236
           G         + +A            G + +   II+  +   +   ++G+  Y+ +  L
Sbjct: 112 GLFAFGLPGKLVVAGTIIIQNI----GAMSSYLLIIKTELPAAIAEFLTGD--YSRYWYL 165

Query: 237 PVSQKSWSIIATAVLLPCAFLKNLK--------------------AVSKFSLLCTLAHFV 276
              Q    II   ++ P A L  +                      + K+S+ C L    
Sbjct: 166 D-GQTLLIIICVGIVFPLALLPKIGFLGYTSSLSFFFMMFFALVVIIKKWSIPCPLT--- 221

Query: 277 INILVIAYCLSRARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEF 336
           +N +   + +S   D    K K +   K+   ++  + FS+     +  +   +Q PS+ 
Sbjct: 222 LNYVEKGFQISNVTDDC--KPKLFHFSKESAYALPTMAFSFLCHTSILPIYCELQSPSKK 279

Query: 337 HCMMNWTHIAACV---LKGLFALVAYLTWADETKEVITDNLPGSIR-----AVVNIFLVA 388
             M N T+ A  +   +  + AL  YLT+ D+ +  +       +        V + ++ 
Sbjct: 280 R-MQNVTNTAIALSFLIYFISALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILF 338

Query: 389 KALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYSGDGRLKSWGLTLRCALVVFTLLMAI 448
             LL+ PL  F A + +    F       FP  +     ++ + +TL  AL +  +L+AI
Sbjct: 339 AVLLTVPLIHFPARKAVTMMFFSN-----FPFSW-----IRHFLITL--ALNIIIVLLAI 386

Query: 449 YVPHFALLMGLTGSLTGAGLCFLLPSLFHLR------LLWRKL 485
           YVP    + G+ G+ T   L F+ P LF+L+      L W+KL
Sbjct: 387 YVPDIRNVFGVVGASTSTCLIFIFPGLFYLKLSREDFLSWKKL 429


>gi|21361602 solute carrier family 38, member 2 [Homo sapiens]
          Length = 506

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 87/429 (20%), Positives = 174/429 (40%), Gaps = 62/429 (14%)

Query: 123 WNVTNAIQGMFVLGLPYAILHGGY-LGLFLIIFAAVVCCYTGKILIACLYEENEDGEVVR 181
           +N++NAI G  +LGL YA+ + G  L + L+ F ++   Y+  +L   L   NE G ++ 
Sbjct: 78  FNLSNAIVGSGILGLSYAMANTGIALFIILLTFVSIFSLYSVHLL---LKTANEGGSLLY 134

Query: 182 VRDSY--------VAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNSF 233
            +  Y        +A + +        +   +  V   + LV+  +  +     L Y + 
Sbjct: 135 EQLGYKAFGLVGKLAASGSITMQNIGAMSSYLFIVKYELPLVIQALTNIEDKTGLWYLNG 194

Query: 234 PGLPVSQKSWSIIATAVLLPCAFLKNLKAV---SKFSLLCTLAHFVINI----------- 279
             L +      +++  V+LP +  +NL  +   S  SLLC +   ++ I           
Sbjct: 195 NYLVL------LVSLVVILPLSLFRNLGYLGYTSGLSLLCMVFFLIVVICKKFQVPCPVE 248

Query: 280 --LVIAYCLSRARDWAWEKVK---------------FYIDVKKFPISIGIIVFSYTSQIF 322
             L+I   ++         V                ++I   +   ++ I++FS+     
Sbjct: 249 AALIINETINTTLTQPTALVPALSHNVTENDSCRPHYFIFNSQTVYAVPILIFSFVCHPA 308

Query: 323 LPSLEGNMQQPSEFHCMMNWTHI---AACVLKGLFALVAYLTWADETKEVITDNLPGSIR 379
           +  +   ++  S    MMN + I   A  ++  L AL  YLT+ +  +  +       + 
Sbjct: 309 VLPIYEELKDRSRRR-MMNVSKISFFAMFLMYLLAALFGYLTFYEHVESELLHTYSSILG 367

Query: 380 AVVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYSGDGRLKSWGLTL-RCA 438
             + + +V  A+L       A    +   +F   S      C S D     W  +L   +
Sbjct: 368 TDILLLIVRLAVL------MAVTLTVPVVIFPIRSSVTHLLCASKD--FSWWRHSLITVS 419

Query: 439 LVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLLWRKLLWHQVFFDVAIFV 498
           ++ FT L+ I+VP    + G  G+   + L F+LPS F+++L+ ++ +          F+
Sbjct: 420 ILAFTNLLVIFVPTIRDIFGFIGASAASMLIFILPSAFYIKLVKKEPMKSVQKIGALFFL 479

Query: 499 IGGICSVSG 507
           + G+  ++G
Sbjct: 480 LSGVLVMTG 488


>gi|122937281 solute carrier family 38, member 8 [Homo sapiens]
          Length = 435

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 73/372 (19%), Positives = 149/372 (40%), Gaps = 48/372 (12%)

Query: 131 GMFVLGLPYAILH-GGYLGLFLIIFAAVVCCYTGKILIACLYEENEDGEVVRVRDSYVAI 189
           G  +L  P+A    GG +  FL+   ++V   +G +++   Y     G+      +Y  +
Sbjct: 39  GAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISGLVILG--YAAAVSGQA-----TYQGV 91

Query: 190 ANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGN----LMYNSFPGLPVSQKSW-- 243
               C P      G++     ++ L+M  + ++ V G+    L  +   G P + + W  
Sbjct: 92  VRGLCGPAI----GKLCEACFLLNLLMISVAFLRVIGDQLEKLCDSLLSGTPPAPQPWYA 147

Query: 244 ------SIIATAVLLPCAFLKNLKAVSKFSLLCTLAH-FVINILVIAYCL-----SRARD 291
                  +++  V+LP +  + +      S+L TLA  ++  ++ + Y L      R   
Sbjct: 148 DQRFTLPLLSVLVILPLSAPREIAFQKYTSILGTLAACYLALVITVQYYLWPQGLVRESH 207

Query: 292 WAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMN--WTHIAACV 349
            +     +      FP     I F +       S+  +M++ S  H  +    + +A C+
Sbjct: 208 PSLSPASWTSVFSVFPT----ICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCL 263

Query: 350 LKGLFALVAYLTWADETKEVITDNLPGS--IRAVVNIFLVAKALLSYPLPFFAAVEVLEK 407
           +  L  +  +LT+  E    +  + PG+  +  V  +      +  YP+  F     L +
Sbjct: 264 IYSLTGVYGFLTFGTEVSADVLMSYPGNDMVIIVARVLFAVSIVTVYPIVLF-----LGR 318

Query: 408 SLFQEGSRAFFPACYSGDGRLKSWGLTLRCAL----VVFTLLMAIYVPHFALLMGLTGSL 463
           S+ Q+  R      +         GL +R  L    V  TL MA+++P  + ++ + G +
Sbjct: 319 SVMQDFWRRSCLGGWGPSALADPSGLWVRMPLTILWVTVTLAMALFMPDLSEIVSIIGGI 378

Query: 464 TGAGLCFLLPSL 475
           + +   F+ P L
Sbjct: 379 S-SFFIFIFPGL 389


>gi|222418629 solute carrier family 38, member 9 [Homo sapiens]
          Length = 561

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 65/301 (21%), Positives = 129/301 (42%), Gaps = 41/301 (13%)

Query: 225 SGNLMYNSFPGLPVSQKSWSIIATA------VLLPCAFLKNLKAVSKFSLLCTLAHFVIN 278
           S  + Y +  G    +K W    T       +LLP    K+    SKF++L T++   + 
Sbjct: 267 SSMIFYANDTGAQQFEKWWDKSRTVPFYLVGLLLPLLNFKSPSFFSKFNILGTVSVLYLI 326

Query: 279 ILVI--AYCLSRARDWAWE-KVKFYI-DVK-KFPISIGIIVFSY-TSQIFLPSLEGNMQQ 332
            LV   A  L    ++ W    +F++ +++ +FP   G++  ++      +  L+ N +Q
Sbjct: 327 FLVTFKAVRLGFHLEFHWFIPTEFFVPEIRFQFPQLTGVLTLAFFIHNCIITLLKNNKKQ 386

Query: 333 PSEFHCMMNWTHIAACVLKGLFALVAYLTWA---------DETKEVITDNLPGS--IRAV 381
            +    +     IA  ++   +  +  L +A         D  ++   DN P S  +  +
Sbjct: 387 ENNVRDLC----IAYMLVTLTYLYIGVLVFASFPSPPLSKDCIEQNFLDNFPSSDTLSFI 442

Query: 382 VNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYSGDGRLKSWGLTLRCALVV 441
             IFL+ + +  YPL  + A   L   +F +     +P+ +          L L   +V 
Sbjct: 443 ARIFLLFQMMTVYPLLGYLARVQLLGHIFGD----IYPSIFHV--------LILNLIIVG 490

Query: 442 FTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLLWR--KLLWHQVFFDVAIFVI 499
             ++MA + P+   ++  +G+  G    F+ PSL ++  L +  +L W ++ F V I ++
Sbjct: 491 AGVIMACFYPNIGGIIRYSGAACGLAFVFIYPSLIYIISLHQEERLTWPKLIFHVFIIIL 550

Query: 500 G 500
           G
Sbjct: 551 G 551



 Score = 29.3 bits (64), Expect = 9.2
 Identities = 22/109 (20%), Positives = 46/109 (42%), Gaps = 8/109 (7%)

Query: 125 VTNAIQGMFVLGLPYAILHGGYL-GLFLIIFAAVVCCYTGKILIACLYEENEDGEVVRVR 183
           + N + G  +L +P+ I   G+  G+ +II   ++  Y       C Y   +   ++   
Sbjct: 126 IWNTMMGTSILSIPWGIKQAGFTTGMCVIILMGLLTLY-------CCYRVVKSRTMMFSL 178

Query: 184 DSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSGNLMYNS 232
           D+        C   F + G     +  ++ L+   I+Y V+  N ++N+
Sbjct: 179 DTTSWEYPDVCRHYFGSFGQWSSLLFSLVSLIGAMIVYWVLMSNFLFNT 227


>gi|5870893 solute carrier family 38, member 3 [Homo sapiens]
          Length = 504

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 81/411 (19%), Positives = 171/411 (41%), Gaps = 79/411 (19%)

Query: 123 WNVTNAIQGMFVLGLPYAILHGG-YLGLFLIIFAAVVCCYTGKILIACLYEENEDGEVVR 181
           +N++NAI G  +LGL YA+ + G  L LFL+   A++  Y+  +L+       +   VV 
Sbjct: 73  FNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLL-------KSSGVVG 125

Query: 182 VRDSYVAIANACCAPRFPTLGGRVVNVAQIIELV--MTCILYVVVSG-NLMYNSFPGLPV 238
           +R +Y  +        F T G     +A  ++ +  M+  LY++ S   L+  +F  L  
Sbjct: 126 IR-AYEQLGYRA----FGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEE 180

Query: 239 SQKSW--------SIIATAVLLPCAFLKNLKAV---SKFSLLCTLAHFVINILVIAYCLS 287
               W         +++  ++LP A ++ L  +   S FSL C +  F+I ++   + + 
Sbjct: 181 KTSDWYMNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSC-MVFFLIAVIYKKFHVP 239

Query: 288 --------------RARDWAWEKVKFYIDVK--------------KFPISIGIIVFSYTS 319
                            +   EKV+  ++ +              +   +I I+ F++  
Sbjct: 240 CPLPPNFNNTTGNFSHVEIVKEKVQLQVEPEASAFCTPSYFTLNSQTAYTIPIMAFAFVC 299

Query: 320 QIFLPSLEGNMQQPS--EFHCMMNWTHIAACVLKGLFALVAYLTWADETKEVITDNL--- 374
              +  +   ++ PS  +   + N +     ++  L AL  YLT+ +  +  +       
Sbjct: 300 HPEVLPIYTELKDPSKKKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHTYSKV 359

Query: 375 -PGSIRAV-VNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYSGDGRLKSW- 431
            P  +  + V + ++    L+ P+  F     +++ LF   ++ F            SW 
Sbjct: 360 DPFDVLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFP--NQEF------------SWL 405

Query: 432 -GLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLL 481
             + +   L+    L+ I+ P+   + G+ G+ +   L F+ P++F+ R++
Sbjct: 406 RHVLIAVGLLTCINLLVIFAPNILGIFGVIGATSAPFLIFIFPAIFYFRIM 456


>gi|219689132 solute carrier family 38, member 4 [Homo sapiens]
          Length = 547

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 52/237 (21%), Positives = 107/237 (45%), Gaps = 38/237 (16%)

Query: 121 AGWNVTNAIQGMFVLGLPYAILHGG-YLGLFLIIFAAVVCCYTGKILIACLYEENEDGEV 179
           + +N++NAI G  +LGL YA+ + G  L + +++  A++  Y+  +L   L    E G +
Sbjct: 80  SSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLL---LKTAKEGGSL 136

Query: 180 VRVRDSYVAIANACCAPRFPTLGGRVVNVA-QIIELVMTCILYVVVSGNLMYNSFPGLPV 238
           +  +    A         +P   G  V++  Q I  + + +  +      +  +F GL  
Sbjct: 137 IYEKLGEKAFG-------WPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLEE 189

Query: 239 SQKSWSI--------IATAVLLPCAFLKNLKAV---SKFSLLCTLAHFVINILVIAYCLS 287
           +   W +        ++  ++LP + LKNL  +   S FSL C +  F +++++      
Sbjct: 190 NTGEWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMV--FFVSVVI------ 241

Query: 288 RARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTH 344
                 ++K +    +     S+G + F+ T  + +  L  N  + S+ + MM++TH
Sbjct: 242 ------YKKFQIPCPLPVLDHSVGNLSFNNTLPMHVVMLPNN-SESSDVNFMMDYTH 291



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 45/222 (20%), Positives = 92/222 (41%), Gaps = 29/222 (13%)

Query: 298 KFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPS--EFHCMMNWTHIAACVLKGLFA 355
           K+++   +   +I I+VF++     +  +   ++  S  +   + N +     V+  L A
Sbjct: 324 KYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAA 383

Query: 356 LVAYLTWADETKE--------VITDNLPGSIRAVVNIFLVAKALLSYPLPFFAAVEVLEK 407
           L  YLT+  E ++        V T ++P     +V + ++    L+ P+  F     +  
Sbjct: 384 LFGYLTFYGEVEDELLHAYSKVYTLDIP---LLMVRLAVLVAVTLTVPIVLFPIRTSVIT 440

Query: 408 SLFQEGSRAFFPACYSGDGRLKSW--GLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTG 465
            LF +              R  SW     +   L+    ++ I VP    + G  G+ + 
Sbjct: 441 LLFPK--------------RPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSA 486

Query: 466 AGLCFLLPSLFHLRLLWRKLLWHQVFFDVAIFVIGGICSVSG 507
             L F+LP++F+L+L+ ++           IF++ GI  + G
Sbjct: 487 TMLIFILPAVFYLKLVKKETFRSPQKVGALIFLVVGIFFMIG 528


>gi|18482385 solute carrier family 38, member 4 [Homo sapiens]
          Length = 547

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 52/237 (21%), Positives = 107/237 (45%), Gaps = 38/237 (16%)

Query: 121 AGWNVTNAIQGMFVLGLPYAILHGG-YLGLFLIIFAAVVCCYTGKILIACLYEENEDGEV 179
           + +N++NAI G  +LGL YA+ + G  L + +++  A++  Y+  +L   L    E G +
Sbjct: 80  SSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLL---LKTAKEGGSL 136

Query: 180 VRVRDSYVAIANACCAPRFPTLGGRVVNVA-QIIELVMTCILYVVVSGNLMYNSFPGLPV 238
           +  +    A         +P   G  V++  Q I  + + +  +      +  +F GL  
Sbjct: 137 IYEKLGEKAFG-------WPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLEE 189

Query: 239 SQKSWSI--------IATAVLLPCAFLKNLKAV---SKFSLLCTLAHFVINILVIAYCLS 287
           +   W +        ++  ++LP + LKNL  +   S FSL C +  F +++++      
Sbjct: 190 NTGEWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMV--FFVSVVI------ 241

Query: 288 RARDWAWEKVKFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTH 344
                 ++K +    +     S+G + F+ T  + +  L  N  + S+ + MM++TH
Sbjct: 242 ------YKKFQIPCPLPVLDHSVGNLSFNNTLPMHVVMLPNN-SESSDVNFMMDYTH 291



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 45/222 (20%), Positives = 92/222 (41%), Gaps = 29/222 (13%)

Query: 298 KFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQQPS--EFHCMMNWTHIAACVLKGLFA 355
           K+++   +   +I I+VF++     +  +   ++  S  +   + N +     V+  L A
Sbjct: 324 KYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAA 383

Query: 356 LVAYLTWADETKE--------VITDNLPGSIRAVVNIFLVAKALLSYPLPFFAAVEVLEK 407
           L  YLT+  E ++        V T ++P     +V + ++    L+ P+  F     +  
Sbjct: 384 LFGYLTFYGEVEDELLHAYSKVYTLDIP---LLMVRLAVLVAVTLTVPIVLFPIRTSVIT 440

Query: 408 SLFQEGSRAFFPACYSGDGRLKSW--GLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTG 465
            LF +              R  SW     +   L+    ++ I VP    + G  G+ + 
Sbjct: 441 LLFPK--------------RPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSA 486

Query: 466 AGLCFLLPSLFHLRLLWRKLLWHQVFFDVAIFVIGGICSVSG 507
             L F+LP++F+L+L+ ++           IF++ GI  + G
Sbjct: 487 TMLIFILPAVFYLKLVKKETFRSPQKVGALIFLVVGIFFMIG 528


>gi|8922692 solute carrier family 38, member 7 [Homo sapiens]
          Length = 462

 Score = 38.1 bits (87), Expect = 0.020
 Identities = 84/434 (19%), Positives = 152/434 (35%), Gaps = 75/434 (17%)

Query: 109 GGHDKPKITAWEAGWNVTNAIQGMFVLGLPYAI-LHGGYLGLFLIIFAAVVCCYTGKILI 167
           GG D+   +   A + V NA  G  +L  P A    GG      +    +V   +G +++
Sbjct: 44  GGLDRGTTSTLGAIFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVIL 103

Query: 168 A-CLYEENEDGEVVRVRDSYVAIANACCAPRFPTLGGRVVNVAQIIELVMTCILYVVVSG 226
           A C    NE         +Y  +  A C      L G +  VA  +    TCI ++++ G
Sbjct: 104 AYCSQASNER--------TYQEVVWAVCGK----LTGVLCEVAIAVYTFGTCIAFLIIIG 151

Query: 227 NLMYN------------SFPGLPVSQKSWSIIATAVLLPCAFLKNLKAVSKFSLLCTLAH 274
           +                S P     + + S+ A   +LP +  + +      S L  +  
Sbjct: 152 DQQDKIIAVMAKEPEGASGPWYTDRKFTISLTAFLFILPLSIPREIGFQKYASFLSVVGT 211

Query: 275 FVINILVIAYCLSRARDWAW-EKVKFYIDVKKFPIS-------IGIIVFSYTSQIFLPSL 326
           + +  +VI         + W +K     ++   P S       +  I F +   +    +
Sbjct: 212 WYVTAIVII-------KYIWPDKEMTPGNILTRPASWMAVFNAMPTICFGFQCHVSSVPV 264

Query: 327 EGNMQQPSEFHCMMNWTHIAACVLKGLFA------LVAYLTWADETKEVITDNLPGSIRA 380
             +MQQP     +  W  +    +    A      +  +LT+       +  + P    A
Sbjct: 265 FNSMQQPE----VKTWGGVVTAAMVIALAVYMGTGICGFLTFGAAVDPDVLLSYPSEDMA 320

Query: 381 VV--NIFLVAKALLSYPLPFFAAVEVLEKSLFQEGSRAFFPACYSG------DGRLKSWG 432
           V     F++   L SYP+  F    V+E    +          Y G       GR +   
Sbjct: 321 VAVARAFIILSVLTSYPILHFCGRAVVEGLWLR----------YQGVPVEEDVGRERRRR 370

Query: 433 LTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGA------GLCFLLPSLFHLRLLWRKLL 486
           +       + TLL+A+++P    ++ + G L         GLC +   L  +  +     
Sbjct: 371 VLQTLVWFLLTLLLALFIPDIGKVISVIGGLAACFIFVFPGLCLIQAKLSEMEEVKPASW 430

Query: 487 WHQVFFDVAIFVIG 500
           W  V + V +  +G
Sbjct: 431 WVLVSYGVLLVTLG 444


>gi|112382239 desmuslin isoform B [Homo sapiens]
          Length = 1253

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 2/62 (3%)

Query: 55   RQGLQMDILKAEGEPCGDEGAEAPVEGDIHYQRGSGAPL-PPSGSKDQVGGGGEFGGHDK 113
            R+ L      A G P  + GAEAP  G I ++R +   L  PSG  +  GG     G   
Sbjct: 1036 RESLSRQRSPAPGSPDEEGGAEAPAAG-IRFRRWATRELYIPSGESEVAGGASHSSGQRT 1094

Query: 114  PK 115
            P+
Sbjct: 1095 PQ 1096


>gi|112382237 desmuslin isoform A [Homo sapiens]
          Length = 1565

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 2/62 (3%)

Query: 55   RQGLQMDILKAEGEPCGDEGAEAPVEGDIHYQRGSGAPL-PPSGSKDQVGGGGEFGGHDK 113
            R+ L      A G P  + GAEAP  G I ++R +   L  PSG  +  GG     G   
Sbjct: 1036 RESLSRQRSPAPGSPDEEGGAEAPAAG-IRFRRWATRELYIPSGESEVAGGASHSSGQRT 1094

Query: 114  PK 115
            P+
Sbjct: 1095 PQ 1096


>gi|44662807 hypothetical protein LOC388407 [Homo sapiens]
          Length = 251

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 5/60 (8%)

Query: 97  GSKDQVGGGGEFGGHDKPKITAW--EAGW---NVTNAIQGMFVLGLPYAILHGGYLGLFL 151
           G+   +GG    G    P  +A+  EAG    NV+   +G F LGLP+ +  G YL L L
Sbjct: 71  GAPALLGGSPSSGSPGHPPGSAFGVEAGCRALNVSEHARGGFALGLPFGLSGGAYLFLLL 130


>gi|84662753 G protein-coupled receptor 149 [Homo sapiens]
          Length = 731

 Score = 30.8 bits (68), Expect = 3.2
 Identities = 19/59 (32%), Positives = 24/59 (40%)

Query: 419 PACYSGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFH 477
           P C  G      WG  + C+      L  +Y   F LL+GL+  LT   LC   P   H
Sbjct: 168 PLCGWGAFVRTPWGCLVDCSSSYVLFLSIVYALAFGLLVGLSVPLTHRLLCSEEPPRLH 226


>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
          Length = 1497

 Score = 30.0 bits (66), Expect = 5.4
 Identities = 18/48 (37%), Positives = 21/48 (43%), Gaps = 6/48 (12%)

Query: 69  PCGDEGAEAPVEGDIHYQRGSGAPLPPSGSKDQVGGGGEFGGHDKPKI 116
           P G  G E P+       RG   P P SG K + G  GE G H  P +
Sbjct: 619 PMGQRGREGPMG-----PRGEAGP-PGSGEKGERGAAGEPGPHGPPGV 660


>gi|153792144 ATP-binding cassette, sub-family A, member 10 [Homo
           sapiens]
          Length = 1543

 Score = 29.6 bits (65), Expect = 7.1
 Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 5/52 (9%)

Query: 430 SWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCFLLPSLFHLRLL 481
           SWGLT  C + + ++ MA+ +    ++       TG  + F L SL+ L L+
Sbjct: 179 SWGLTYICFIFIMSIFMALVITSIPIVFH-----TGFMVIFTLYSLYGLSLI 225


>gi|238231392 dedicator of cytokinesis 8 [Homo sapiens]
          Length = 2099

 Score = 29.3 bits (64), Expect = 9.2
 Identities = 16/54 (29%), Positives = 26/54 (48%), Gaps = 6/54 (11%)

Query: 3    TLLRSKLSNVATSVSNKSQAKMSGMFARMGFQAATDEEAVGFAHCDDLDFEHRQ 56
            TL  SKL     S+ NK   +M G + R+GF  +       F   D+ +F +++
Sbjct: 1769 TLTHSKLQRAFDSIVNKDHKRMFGTYFRVGFFGSK------FGDLDEQEFVYKE 1816


>gi|157388943 transmembrane protein 104 [Homo sapiens]
          Length = 496

 Score = 29.3 bits (64), Expect = 9.2
 Identities = 49/251 (19%), Positives = 93/251 (37%), Gaps = 35/251 (13%)

Query: 246 IATAVLLPCAFLKNLKAVSKFSLLCTLAHFVINILVIAYCLSRARDWAWEKVKFYIDVKK 305
           I T +L P  F  +++      +L +L  ++   ++I   L R      E      D   
Sbjct: 214 IFTLLLGPFTFF-DVQKTKYLQILTSLMRWIAFAVMIVLALIRIGHGQGEGHPPLADFSG 272

Query: 306 FPISIGIIVFSYTSQIFLPSLEGNMQQPSEFHCMMNWTHIAACVLKGLFALVAYLTW-AD 364
                G+ V+S+  Q  LPSL   +        ++   ++      GL +  A   +  D
Sbjct: 273 VRNLFGVCVYSFMCQHSLPSLITPVSSKRHLTRLVFLDYVLILAFYGLLSFTAIFCFRGD 332

Query: 365 ETKEVITDNLP-------GSIRAVVNIFLVAKALLSYPLPFFAAVEVLEKSLFQEGS--- 414
              ++ T N          ++R  + +F V     ++P+         +    +EG    
Sbjct: 333 SLMDMYTLNFARCDVVGLAAVRFFLGLFPVFTISTNFPIIAVTLRNNWKTLFHREGGTYP 392

Query: 415 ----RAFFPACYSGDGRLKSWGLTLRCALVVFTLLMAIYVPHFALLMGLTGSLTGAGLCF 470
               R  FP             +TL     V  +L+A        L+G+TG+  G G+ +
Sbjct: 393 WVVDRVVFPT------------ITL-----VPPVLVAFCTHDLESLVGITGAYAGTGIQY 435

Query: 471 LLPS--LFHLR 479
           ++P+  ++H R
Sbjct: 436 VIPAFLVYHCR 446


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.140    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,424,772
Number of Sequences: 37866
Number of extensions: 897472
Number of successful extensions: 2790
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2753
Number of HSP's gapped (non-prelim): 33
length of query: 525
length of database: 18,247,518
effective HSP length: 107
effective length of query: 418
effective length of database: 14,195,856
effective search space: 5933867808
effective search space used: 5933867808
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.