BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|17981696 cyclin-dependent kinase inhibitor 2B isoform 2 [Homo sapiens] (78 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|17981696 cyclin-dependent kinase inhibitor 2B isoform 2 [Homo... 157 2e-39 gi|17981694 cyclin-dependent kinase inhibitor 2B isoform 1 [Homo... 106 4e-24 gi|4502749 cyclin-dependent kinase inhibitor 2A isoform 1 [Homo ... 51 2e-07 gi|98985804 cyclin-dependent kinase inhibitor 2A isoform 3 [Homo... 51 2e-07 gi|62988328 ankyrin repeat domain 50 [Homo sapiens] 40 5e-04 gi|17981699 cyclin-dependent kinase inhibitor 2C [Homo sapiens] 38 0.002 gi|4502751 cyclin-dependent kinase inhibitor 2C [Homo sapiens] 38 0.002 gi|4502753 cyclin-dependent kinase inhibitor 2D [Homo sapiens] 36 0.008 gi|17981702 cyclin-dependent kinase inhibitor 2D [Homo sapiens] 36 0.008 gi|215598824 ankyrin repeat and SOCS box-containing 10 isoform 2... 33 0.038 gi|215598819 ankyrin repeat and SOCS box-containing 10 isoform 1... 33 0.038 gi|215598806 ankyrin repeat and SOCS box-containing 10 isoform 3... 33 0.038 gi|109150435 ankyrin repeat and zinc finger domain containing 1 ... 33 0.064 gi|109150425 ankyrin repeat and zinc finger domain containing 1 ... 33 0.064 gi|89941470 ankyrin repeat domain 34 [Homo sapiens] 33 0.064 gi|157743284 ankyrin repeat domain 52 [Homo sapiens] 32 0.11 gi|20270347 ankyrin repeat domain 54 [Homo sapiens] 32 0.14 gi|223634006 hypothetical protein LOC441869 [Homo sapiens] 31 0.19 gi|24586688 ankyrin repeat and SOCS box-containing protein 16 [H... 31 0.19 gi|68131557 ankyrin repeat domain 28 [Homo sapiens] 31 0.24 gi|13540606 caseinolytic peptidase B [Homo sapiens] 31 0.24 gi|38176283 ankyrin repeat and SOCS box-containing protein 7 iso... 30 0.32 gi|92087060 ankyrin repeat and SOCS box-containing 15 [Homo sapi... 30 0.32 gi|30089994 ankyrin repeat and SOCS box-containing protein 7 iso... 30 0.32 gi|55770876 notch4 preproprotein [Homo sapiens] 30 0.42 gi|7705268 family with sequence similarity 8, member A1 [Homo sa... 30 0.42 gi|52426737 ankyrin 2 isoform 2 [Homo sapiens] 30 0.54 gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 30 0.54 gi|7657265 fem-1 homolog b [Homo sapiens] 29 0.71 gi|72534772 ankyrin repeat and SOCS box-containing 9 isoform 1 [... 29 0.71 >gi|17981696 cyclin-dependent kinase inhibitor 2B isoform 2 [Homo sapiens] Length = 78 Score = 157 bits (396), Expect = 2e-39 Identities = 78/78 (100%), Positives = 78/78 (100%) Query: 1 MREENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPGPR 60 MREENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPGPR Sbjct: 1 MREENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPGPR 60 Query: 61 RQGARERGARPRRIGAGT 78 RQGARERGARPRRIGAGT Sbjct: 61 RQGARERGARPRRIGAGT 78 >gi|17981694 cyclin-dependent kinase inhibitor 2B isoform 1 [Homo sapiens] Length = 138 Score = 106 bits (265), Expect = 4e-24 Identities = 53/53 (100%), Positives = 53/53 (100%) Query: 1 MREENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQV 53 MREENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQV Sbjct: 1 MREENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQV 53 >gi|4502749 cyclin-dependent kinase inhibitor 2A isoform 1 [Homo sapiens] Length = 156 Score = 51.2 bits (121), Expect = 2e-07 Identities = 30/49 (61%), Positives = 34/49 (69%), Gaps = 4/49 (8%) Query: 9 PSGGGSDEG----LASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQV 53 P+ G S E LA+AAARG VE+VR LLEAGA PN N +GRR IQV Sbjct: 3 PAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQV 51 >gi|98985804 cyclin-dependent kinase inhibitor 2A isoform 3 [Homo sapiens] Length = 116 Score = 51.2 bits (121), Expect = 2e-07 Identities = 30/49 (61%), Positives = 34/49 (69%), Gaps = 4/49 (8%) Query: 9 PSGGGSDEG----LASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQV 53 P+ G S E LA+AAARG VE+VR LLEAGA PN N +GRR IQV Sbjct: 3 PAAGSSMEPSADWLATAAARGRVEEVRALLEAGALPNAPNSYGRRPIQV 51 >gi|62988328 ankyrin repeat domain 50 [Homo sapiens] Length = 1429 Score = 39.7 bits (91), Expect = 5e-04 Identities = 20/41 (48%), Positives = 27/41 (65%) Query: 18 LASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPG 58 L AA G ++ V+ LLE GADPN ++FGR A++VA G Sbjct: 1049 LCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNG 1089 Score = 31.2 bits (69), Expect = 0.19 Identities = 22/59 (37%), Positives = 31/59 (52%), Gaps = 2/59 (3%) Query: 18 LASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPGPRR--QGARERGARPRRI 74 L+ A+A+G VE VR LL+ G D N + G + +A G R + E+GAR I Sbjct: 818 LSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEI 876 Score = 26.2 bits (56), Expect = 6.0 Identities = 16/41 (39%), Positives = 21/41 (51%) Query: 18 LASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPG 58 L AA G V+ V LLE GAD + + GR + A + G Sbjct: 752 LLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMG 792 >gi|17981699 cyclin-dependent kinase inhibitor 2C [Homo sapiens] Length = 168 Score = 38.1 bits (87), Expect = 0.002 Identities = 24/55 (43%), Positives = 31/55 (56%), Gaps = 1/55 (1%) Query: 18 LASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPGPR-RQGARERGARP 71 LASAAARG +E++ LL+ + N N FGR A+QV P + RGA P Sbjct: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANP 63 >gi|4502751 cyclin-dependent kinase inhibitor 2C [Homo sapiens] Length = 168 Score = 38.1 bits (87), Expect = 0.002 Identities = 24/55 (43%), Positives = 31/55 (56%), Gaps = 1/55 (1%) Query: 18 LASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPGPR-RQGARERGARP 71 LASAAARG +E++ LL+ + N N FGR A+QV P + RGA P Sbjct: 9 LASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANP 63 >gi|4502753 cyclin-dependent kinase inhibitor 2D [Homo sapiens] Length = 166 Score = 35.8 bits (81), Expect = 0.008 Identities = 19/37 (51%), Positives = 27/37 (72%), Gaps = 1/37 (2%) Query: 18 LASAAARGLVEKVRQLLEAG-ADPNGVNRFGRRAIQV 53 L+ AAARG V++VR+LL P+ +NRFG+ A+QV Sbjct: 12 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQV 48 >gi|17981702 cyclin-dependent kinase inhibitor 2D [Homo sapiens] Length = 166 Score = 35.8 bits (81), Expect = 0.008 Identities = 19/37 (51%), Positives = 27/37 (72%), Gaps = 1/37 (2%) Query: 18 LASAAARGLVEKVRQLLEAG-ADPNGVNRFGRRAIQV 53 L+ AAARG V++VR+LL P+ +NRFG+ A+QV Sbjct: 12 LSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQV 48 >gi|215598824 ankyrin repeat and SOCS box-containing 10 isoform 2 [Homo sapiens] Length = 474 Score = 33.5 bits (75), Expect = 0.038 Identities = 19/49 (38%), Positives = 24/49 (48%) Query: 10 SGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPG 58 S G L A A G V LL AGADPN ++ G+R + + PG Sbjct: 189 SAPGGRTALHEACAAGHTACVHVLLVAGADPNIADQDGKRPLHLCRGPG 237 >gi|215598819 ankyrin repeat and SOCS box-containing 10 isoform 1 [Homo sapiens] Length = 512 Score = 33.5 bits (75), Expect = 0.038 Identities = 19/49 (38%), Positives = 24/49 (48%) Query: 10 SGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPG 58 S G L A A G V LL AGADPN ++ G+R + + PG Sbjct: 189 SAPGGRTALHEACAAGHTACVHVLLVAGADPNIADQDGKRPLHLCRGPG 237 >gi|215598806 ankyrin repeat and SOCS box-containing 10 isoform 3 [Homo sapiens] Length = 452 Score = 33.5 bits (75), Expect = 0.038 Identities = 19/49 (38%), Positives = 24/49 (48%) Query: 10 SGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPG 58 S G L A A G V LL AGADPN ++ G+R + + PG Sbjct: 129 SAPGGRTALHEACAAGHTACVHVLLVAGADPNIADQDGKRPLHLCRGPG 177 >gi|109150435 ankyrin repeat and zinc finger domain containing 1 [Homo sapiens] Length = 726 Score = 32.7 bits (73), Expect = 0.064 Identities = 23/57 (40%), Positives = 26/57 (45%) Query: 9 PSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPGPRRQGAR 65 P G G L +AAA G VR LLEAGADP + R VA R + R Sbjct: 530 PLGSGGFTLLHAAAAAGRGSVVRLLLEAGADPTVQDSRARPPYTVAADKSTRNEFRR 586 >gi|109150425 ankyrin repeat and zinc finger domain containing 1 [Homo sapiens] Length = 726 Score = 32.7 bits (73), Expect = 0.064 Identities = 23/57 (40%), Positives = 26/57 (45%) Query: 9 PSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPGPRRQGAR 65 P G G L +AAA G VR LLEAGADP + R VA R + R Sbjct: 530 PLGSGGFTLLHAAAAAGRGSVVRLLLEAGADPTVQDSRARPPYTVAADKSTRNEFRR 586 >gi|89941470 ankyrin repeat domain 34 [Homo sapiens] Length = 496 Score = 32.7 bits (73), Expect = 0.064 Identities = 17/29 (58%), Positives = 19/29 (65%) Query: 30 VRQLLEAGADPNGVNRFGRRAIQVAGAPG 58 VR LLE GADPN +R GR A+ A A G Sbjct: 60 VRYLLEQGADPNIADRLGRTALMHACAGG 88 >gi|157743284 ankyrin repeat domain 52 [Homo sapiens] Length = 1076 Score = 32.0 bits (71), Expect = 0.11 Identities = 16/37 (43%), Positives = 23/37 (62%) Query: 18 LASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVA 54 L +AAA G +E V+ LL GA+ + N FG A+ +A Sbjct: 210 LHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTALHIA 246 Score = 30.0 bits (66), Expect = 0.42 Identities = 17/41 (41%), Positives = 24/41 (58%) Query: 18 LASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPG 58 L +AA+ G VE + LL +GAD ++FGR + A A G Sbjct: 427 LHAAASGGNVECLNLLLSSGADLRRRDKFGRTPLHYAAANG 467 >gi|20270347 ankyrin repeat domain 54 [Homo sapiens] Length = 300 Score = 31.6 bits (70), Expect = 0.14 Identities = 25/63 (39%), Positives = 32/63 (50%), Gaps = 3/63 (4%) Query: 18 LASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPGPRR--QGARERGARP-RRI 74 L +A VE V+QLLE GADP + GR A+ A G + Q + GA P +R Sbjct: 114 LRDSANANDVETVQQLLEDGADPCAADDKGRTALHFASCNGNDQIVQLLLDHGADPNQRD 173 Query: 75 GAG 77 G G Sbjct: 174 GLG 176 >gi|223634006 hypothetical protein LOC441869 [Homo sapiens] Length = 399 Score = 31.2 bits (69), Expect = 0.19 Identities = 19/47 (40%), Positives = 23/47 (48%) Query: 12 GGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPG 58 G L AAA G + + LL GADP +R GR A+ A A G Sbjct: 234 GAGATALGLAAALGRSQDIEVLLGHGADPGIRDRHGRSALHRAAARG 280 Score = 25.8 bits (55), Expect = 7.9 Identities = 18/48 (37%), Positives = 23/48 (47%) Query: 11 GGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPG 58 G G D L AAA G +R LL GA + + G A+ +A A G Sbjct: 200 GAGLDGALLVAAAAGRGAALRFLLARGARVDARDGAGATALGLAAALG 247 >gi|24586688 ankyrin repeat and SOCS box-containing protein 16 [Homo sapiens] Length = 453 Score = 31.2 bits (69), Expect = 0.19 Identities = 29/78 (37%), Positives = 34/78 (43%), Gaps = 10/78 (12%) Query: 8 MPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQV--AGAPGP----RR 61 + +G + L AAARGL + V LE GAD G A+ AGA GP R Sbjct: 204 LAAGESQETPLHVAAARGLEQHVALYLEHGADVGLRTSQGETALNTACAGAEGPGSCRRH 263 Query: 62 QGARER----GARPRRIG 75 Q A R GA R G Sbjct: 264 QAAARRLLEAGADARAAG 281 >gi|68131557 ankyrin repeat domain 28 [Homo sapiens] Length = 1053 Score = 30.8 bits (68), Expect = 0.24 Identities = 14/37 (37%), Positives = 22/37 (59%) Query: 18 LASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVA 54 L +AA+ G++ V+ LL+ G D N N +G + VA Sbjct: 210 LHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVA 246 Score = 30.4 bits (67), Expect = 0.32 Identities = 17/39 (43%), Positives = 23/39 (58%) Query: 18 LASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGA 56 L +AAA G +E + LL GAD N ++FGR + A A Sbjct: 409 LHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAA 447 >gi|13540606 caseinolytic peptidase B [Homo sapiens] Length = 707 Score = 30.8 bits (68), Expect = 0.24 Identities = 17/45 (37%), Positives = 23/45 (51%) Query: 10 SGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVA 54 S D L AA +++V +LL GAD N +R G A+ VA Sbjct: 130 SPSNKDAALLEAARANNMQEVSRLLSEGADVNAKHRLGWTALMVA 174 >gi|38176283 ankyrin repeat and SOCS box-containing protein 7 isoform 2 [Homo sapiens] Length = 318 Score = 30.4 bits (67), Expect = 0.32 Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 2/56 (3%) Query: 18 LASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPGPRR--QGARERGARP 71 + +A A G V VR++LE G PNG + G + + A G R + E GA P Sbjct: 18 IQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADP 73 >gi|92087060 ankyrin repeat and SOCS box-containing 15 [Homo sapiens] Length = 588 Score = 30.4 bits (67), Expect = 0.32 Identities = 18/41 (43%), Positives = 20/41 (48%) Query: 18 LASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPG 58 L A GLVE VR LLE G PN N G + +A G Sbjct: 115 LTLAVKAGLVENVRTLLEKGVWPNTKNDKGETPLLIAVKKG 155 >gi|30089994 ankyrin repeat and SOCS box-containing protein 7 isoform 1 [Homo sapiens] Length = 274 Score = 30.4 bits (67), Expect = 0.32 Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 2/56 (3%) Query: 18 LASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPGPRR--QGARERGARP 71 + +A A G V VR++LE G PNG + G + + A G R + E GA P Sbjct: 18 IQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADP 73 >gi|55770876 notch4 preproprotein [Homo sapiens] Length = 2003 Score = 30.0 bits (66), Expect = 0.42 Identities = 19/49 (38%), Positives = 24/49 (48%) Query: 12 GGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPGPR 60 G + L AA R+LLEAGA+PN +R GR + A A R Sbjct: 1632 GTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAR 1680 >gi|7705268 family with sequence similarity 8, member A1 [Homo sapiens] Length = 413 Score = 30.0 bits (66), Expect = 0.42 Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 5/71 (7%) Query: 2 REENKGMPSGGG--SDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPGP 59 R++ + P G + GLA+AAA +E R+L + G +G G + AG P Sbjct: 40 RDDPQAEPQAPGRPTAPGLAAAAAADKLEPPRELRKRGEAASG---SGAELQEQAGCEAP 96 Query: 60 RRQGARERGAR 70 RER AR Sbjct: 97 EAAAPRERPAR 107 >gi|52426737 ankyrin 2 isoform 2 [Homo sapiens] Length = 1872 Score = 29.6 bits (65), Expect = 0.54 Identities = 16/55 (29%), Positives = 26/55 (47%) Query: 4 ENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPG 58 + + P S+ AA G ++KV + L+ G D N N+ G A+ +A G Sbjct: 21 QRRKRPKKSDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEG 75 >gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] Length = 3957 Score = 29.6 bits (65), Expect = 0.54 Identities = 16/55 (29%), Positives = 26/55 (47%) Query: 4 ENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPG 58 + + P S+ AA G ++KV + L+ G D N N+ G A+ +A G Sbjct: 21 QRRKRPKKSDSNASFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEG 75 >gi|7657265 fem-1 homolog b [Homo sapiens] Length = 627 Score = 29.3 bits (64), Expect = 0.71 Identities = 17/41 (41%), Positives = 20/41 (48%) Query: 18 LASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPG 58 L AA +G + VR LLE ADPN G A+ A G Sbjct: 158 LMIAAYKGHTDVVRYLLEQRADPNAKAHCGATALHFAAEAG 198 >gi|72534772 ankyrin repeat and SOCS box-containing 9 isoform 1 [Homo sapiens] Length = 294 Score = 29.3 bits (64), Expect = 0.71 Identities = 19/69 (27%), Positives = 27/69 (39%) Query: 3 EENKGMPSGGGSDEGLASAAARGLVEKVRQLLEAGADPNGVNRFGRRAIQVAGAPGPRRQ 62 E + G G D L + A E L++ GAD N G+R +++ P Q Sbjct: 188 ESGADVNQGKGQDSPLHAVARTASEELACLLMDFGADTQAKNAEGKRPVELVPPESPLAQ 247 Query: 63 GARERGARP 71 ER P Sbjct: 248 LFLEREGPP 256 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.135 0.385 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 3,457,870 Number of Sequences: 37866 Number of extensions: 150580 Number of successful extensions: 854 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 88 Number of HSP's successfully gapped in prelim test: 33 Number of HSP's that attempted gapping in prelim test: 726 Number of HSP's gapped (non-prelim): 159 length of query: 78 length of database: 18,247,518 effective HSP length: 50 effective length of query: 28 effective length of database: 16,354,218 effective search space: 457918104 effective search space used: 457918104 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.