Search of human proteins with 17978512

Search of human proteins with 17978512

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|17978512 poly-U binding splicing factor 60KDa isoform a
[Homo sapiens]
         (559 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo...  1090   0.0  
gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo...  1046   0.0  
gi|209862867 poly-U binding splicing factor 60KDa isoform c [Hom...  1006   0.0  
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho...   106   5e-23
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo...   106   5e-23
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho...   106   5e-23
gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens]     102   9e-22
gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens]      102   1e-21
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]      98   2e-20
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s...    96   1e-19
gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens]     95   2e-19
gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens]     95   2e-19
gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens]     95   2e-19
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]      94   4e-19
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s...    91   4e-18
gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Hom...    88   2e-17
gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo...    88   2e-17
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                86   9e-17
gi|188219593 TIA1 protein isoform 1 [Homo sapiens]                     85   2e-16
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]      85   2e-16
gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]              83   6e-16
gi|188219591 TIA1 protein isoform 2 [Homo sapiens]                     83   8e-16
gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]             78   2e-14
gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo sa...    75   2e-13
gi|20373175 musashi 2 isoform a [Homo sapiens]                         75   2e-13
gi|25121993 musashi 2 isoform b [Homo sapiens]                         75   2e-13
gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo s...    75   2e-13
gi|187761299 bruno-like 4, RNA binding protein isoform 2 [Homo s...    75   2e-13
gi|224549005 RNA binding motif protein 17 [Homo sapiens]               74   3e-13
gi|14249678 RNA binding motif protein 17 [Homo sapiens]                74   3e-13

>gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo
           sapiens]
          Length = 559

 Score = 1090 bits (2818), Expect = 0.0
 Identities = 559/559 (100%), Positives = 559/559 (100%)

Query: 1   MATATIALQVNGQQGGGSEPAAAAAVVAAGDKWKPPQGTDSIKMENGQSTAAKLGLPPLT 60
           MATATIALQVNGQQGGGSEPAAAAAVVAAGDKWKPPQGTDSIKMENGQSTAAKLGLPPLT
Sbjct: 1   MATATIALQVNGQQGGGSEPAAAAAVVAAGDKWKPPQGTDSIKMENGQSTAAKLGLPPLT 60

Query: 61  PEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAVTMGFGDPLSPLQSMAAQ 120
           PEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAVTMGFGDPLSPLQSMAAQ
Sbjct: 61  PEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAVTMGFGDPLSPLQSMAAQ 120

Query: 121 RQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVP 180
           RQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVP
Sbjct: 121 RQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVP 180

Query: 181 EAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDD 240
           EAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDD
Sbjct: 181 EAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDD 240

Query: 241 DIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVG 300
           DIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVG
Sbjct: 241 DIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVG 300

Query: 301 KAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGLVSPALTL 360
           KAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGLVSPALTL
Sbjct: 301 KAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGLVSPALTL 360

Query: 361 AQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKE 420
           AQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKE
Sbjct: 361 AQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKE 420

Query: 421 EEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLE 480
           EEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLE
Sbjct: 421 EEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLE 480

Query: 481 GEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGR 540
           GEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGR
Sbjct: 481 GEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGR 540

Query: 541 KVVAEVYDQERFDNSDLSA 559
           KVVAEVYDQERFDNSDLSA
Sbjct: 541 KVVAEVYDQERFDNSDLSA 559


>gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo
           sapiens]
          Length = 542

 Score = 1046 bits (2704), Expect = 0.0
 Identities = 542/559 (96%), Positives = 542/559 (96%), Gaps = 17/559 (3%)

Query: 1   MATATIALQVNGQQGGGSEPAAAAAVVAAGDKWKPPQGTDSIKMENGQSTAAKLGLPPLT 60
           MATATIALQVNGQQGGGSEPAAAAAVVAAGDKWKPPQGTDSIKMENGQSTAAKLGLPPLT
Sbjct: 1   MATATIALQVNGQQGGGSEPAAAAAVVAAGDKWKPPQGTDSIKMENGQSTAAKLGLPPLT 60

Query: 61  PEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAVTMGFGDPLSPLQSMAAQ 120
           PEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAA                 Q
Sbjct: 61  PEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAA-----------------Q 103

Query: 121 RQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVP 180
           RQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVP
Sbjct: 104 RQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVP 163

Query: 181 EAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDD 240
           EAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDD
Sbjct: 164 EAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDD 223

Query: 241 DIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVG 300
           DIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVG
Sbjct: 224 DIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVG 283

Query: 301 KAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGLVSPALTL 360
           KAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGLVSPALTL
Sbjct: 284 KAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGLVSPALTL 343

Query: 361 AQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKE 420
           AQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKE
Sbjct: 344 AQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKE 403

Query: 421 EEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLE 480
           EEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLE
Sbjct: 404 EEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLE 463

Query: 481 GEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGR 540
           GEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGR
Sbjct: 464 GEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGR 523

Query: 541 KVVAEVYDQERFDNSDLSA 559
           KVVAEVYDQERFDNSDLSA
Sbjct: 524 KVVAEVYDQERFDNSDLSA 542


>gi|209862867 poly-U binding splicing factor 60KDa isoform c [Homo
           sapiens]
          Length = 516

 Score = 1006 bits (2600), Expect = 0.0
 Identities = 516/516 (100%), Positives = 516/516 (100%)

Query: 44  MENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAV 103
           MENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAV
Sbjct: 1   MENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAV 60

Query: 104 TMGFGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWD 163
           TMGFGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWD
Sbjct: 61  TMGFGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWD 120

Query: 164 SVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEAR 223
           SVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEAR
Sbjct: 121 SVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEAR 180

Query: 224 AFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDA 283
           AFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDA
Sbjct: 181 AFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDA 240

Query: 284 VSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAA 343
           VSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAA
Sbjct: 241 VSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAA 300

Query: 344 VLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPI 403
           VLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPI
Sbjct: 301 VLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPI 360

Query: 404 LASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTV 463
           LASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTV
Sbjct: 361 LASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTV 420

Query: 464 MVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIAS 523
           MVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIAS
Sbjct: 421 MVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIAS 480

Query: 524 ETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA 559
           ETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA
Sbjct: 481 ETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA 516


>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
           sapiens]
          Length = 631

 Score =  106 bits (265), Expect = 5e-23
 Identities = 68/214 (31%), Positives = 117/214 (54%), Gaps = 11/214 (5%)

Query: 93  QQLTNLQMAAVTMGFGDPLS--PLQSMAAQRQRAL--AIMCRVYVGSIYYELGEDTIRQA 148
           QQ  + + A  TM F D +   P++ M +QR  +L  + +  V++ ++   +    +   
Sbjct: 60  QQPADAERALDTMNF-DVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDT 118

Query: 149 FAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNI 208
           F+ FG I S  +  D      KG+AFV +E  EAA  A+E+MN ++L  R + VGR  + 
Sbjct: 119 FSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSR 176

Query: 209 GQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKG 268
            + +    +L  +A+ F  +Y+ +  +++ D+ +K +F  FGK  S  + RDP  GK KG
Sbjct: 177 KEREA---ELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPN-GKSKG 232

Query: 269 YGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 302
           +GF+ YEK + +  AV  MN  ++ G+ + VG+A
Sbjct: 233 FGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRA 266



 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 45/174 (25%), Positives = 88/174 (50%), Gaps = 11/174 (6%)

Query: 128 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 187
           M  +YVG ++ ++ E  + + F+P GP+ SI +  D +T +  G+A+V ++ P  A+ AL
Sbjct: 10  MASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69

Query: 188 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 247
           + MN  ++ G+ I++       Q  P +            +++ ++ + + +  +   F 
Sbjct: 70  DTMNFDVIKGKPIRI----MWSQRDPSL-----RKSGVGNVFIKNLDKSIDNKALYDTFS 120

Query: 248 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 301
           AFG I SC +  D      KGY F+ +E  +++  A+  MN   L  + + VG+
Sbjct: 121 AFGNILSCKVVCDENGS--KGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGR 172



 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 53/185 (28%), Positives = 92/185 (49%), Gaps = 22/185 (11%)

Query: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
           VY+ +   E+ ++++++ F+ FG   S+ +  D    K KGF FV YE  E A  A+E+M
Sbjct: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEM 251

Query: 191 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNR-------------IYVASVHQDL 237
           N   + G+ I VGR      AQ  +++ AE  R F +             +Y+ ++   +
Sbjct: 252 NGKEISGKIIFVGR------AQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTI 305

Query: 238 SDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYL 297
            D+ ++  F  FG I S  +  +   G+ KG+GF+ +   + +  AV+ MN   +G + L
Sbjct: 306 DDEKLRKEFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPL 363

Query: 298 RVGKA 302
            V  A
Sbjct: 364 YVALA 368


>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
           sapiens]
          Length = 644

 Score =  106 bits (265), Expect = 5e-23
 Identities = 68/214 (31%), Positives = 117/214 (54%), Gaps = 11/214 (5%)

Query: 93  QQLTNLQMAAVTMGFGDPLS--PLQSMAAQRQRAL--AIMCRVYVGSIYYELGEDTIRQA 148
           QQ  + + A  TM F D +   P++ M +QR  +L  + +  V++ ++   +    +   
Sbjct: 60  QQPADAERALDTMNF-DVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDT 118

Query: 149 FAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNI 208
           F+ FG I S  +  D      KG+AFV +E  EAA  A+E+MN ++L  R + VGR  + 
Sbjct: 119 FSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSR 176

Query: 209 GQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKG 268
            + +    +L  +A+ F  +Y+ +  +++ D+ +K +F  FGK  S  + RDP  GK KG
Sbjct: 177 KEREA---ELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPN-GKSKG 232

Query: 269 YGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 302
           +GF+ YEK + +  AV  MN  ++ G+ + VG+A
Sbjct: 233 FGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRA 266



 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 45/174 (25%), Positives = 88/174 (50%), Gaps = 11/174 (6%)

Query: 128 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 187
           M  +YVG ++ ++ E  + + F+P GP+ SI +  D +T +  G+A+V ++ P  A+ AL
Sbjct: 10  MASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69

Query: 188 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 247
           + MN  ++ G+ I++       Q  P +            +++ ++ + + +  +   F 
Sbjct: 70  DTMNFDVIKGKPIRI----MWSQRDPSL-----RKSGVGNVFIKNLDKSIDNKALYDTFS 120

Query: 248 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 301
           AFG I SC +  D      KGY F+ +E  +++  A+  MN   L  + + VG+
Sbjct: 121 AFGNILSCKVVCDENGS--KGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGR 172



 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 53/185 (28%), Positives = 92/185 (49%), Gaps = 22/185 (11%)

Query: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
           VY+ +   E+ ++++++ F+ FG   S+ +  D    K KGF FV YE  E A  A+E+M
Sbjct: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEM 251

Query: 191 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNR-------------IYVASVHQDL 237
           N   + G+ I VGR      AQ  +++ AE  R F +             +Y+ ++   +
Sbjct: 252 NGKEISGKIIFVGR------AQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTI 305

Query: 238 SDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYL 297
            D+ ++  F  FG I S  +  +   G+ KG+GF+ +   + +  AV+ MN   +G + L
Sbjct: 306 DDEKLRKEFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPL 363

Query: 298 RVGKA 302
            V  A
Sbjct: 364 YVALA 368


>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
           sapiens]
          Length = 660

 Score =  106 bits (265), Expect = 5e-23
 Identities = 68/214 (31%), Positives = 117/214 (54%), Gaps = 11/214 (5%)

Query: 93  QQLTNLQMAAVTMGFGDPLS--PLQSMAAQRQRAL--AIMCRVYVGSIYYELGEDTIRQA 148
           QQ  + + A  TM F D +   P++ M +QR  +L  + +  V++ ++   +    +   
Sbjct: 60  QQPADAERALDTMNF-DVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDT 118

Query: 149 FAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNI 208
           F+ FG I S  +  D      KG+AFV +E  EAA  A+E+MN ++L  R + VGR  + 
Sbjct: 119 FSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSR 176

Query: 209 GQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKG 268
            + +    +L  +A+ F  +Y+ +  +++ D+ +K +F  FGK  S  + RDP  GK KG
Sbjct: 177 KEREA---ELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDPN-GKSKG 232

Query: 269 YGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 302
           +GF+ YEK + +  AV  MN  ++ G+ + VG+A
Sbjct: 233 FGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRA 266



 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 45/174 (25%), Positives = 88/174 (50%), Gaps = 11/174 (6%)

Query: 128 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 187
           M  +YVG ++ ++ E  + + F+P GP+ SI +  D +T +  G+A+V ++ P  A+ AL
Sbjct: 10  MASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69

Query: 188 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 247
           + MN  ++ G+ I++       Q  P +            +++ ++ + + +  +   F 
Sbjct: 70  DTMNFDVIKGKPIRI----MWSQRDPSL-----RKSGVGNVFIKNLDKSIDNKALYDTFS 120

Query: 248 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 301
           AFG I SC +  D      KGY F+ +E  +++  A+  MN   L  + + VG+
Sbjct: 121 AFGNILSCKVVCDENGS--KGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGR 172



 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 53/185 (28%), Positives = 92/185 (49%), Gaps = 22/185 (11%)

Query: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
           VY+ +   E+ ++++++ F+ FG   S+ +  D    K KGF FV YE  E A  A+E+M
Sbjct: 193 VYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEM 251

Query: 191 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNR-------------IYVASVHQDL 237
           N   + G+ I VGR      AQ  +++ AE  R F +             +Y+ ++   +
Sbjct: 252 NGKEISGKIIFVGR------AQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTI 305

Query: 238 SDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYL 297
            D+ ++  F  FG I S  +  +   G+ KG+GF+ +   + +  AV+ MN   +G + L
Sbjct: 306 DDEKLRKEFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPL 363

Query: 298 RVGKA 302
            V  A
Sbjct: 364 YVALA 368


>gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens]
          Length = 530

 Score =  102 bits (254), Expect = 9e-22
 Identities = 98/437 (22%), Positives = 183/437 (41%), Gaps = 79/437 (18%)

Query: 113 PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGF 172
           P+ ++  + + A  + C      I        + + F+  G ++ + M  D  + + KG 
Sbjct: 141 PIDNLTPEERDARTVFCMQLAARIRPR----DLEEFFSTVGKVRDVRMISDRNSRRSKGI 196

Query: 173 AFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVAS 232
           A+VE+    +  LA+      +LG   I     +   +A  + + L + +    R+YV S
Sbjct: 197 AYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGS 256

Query: 233 VHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDL 292
           +H ++++D ++ +FE FG+I+S  L  D  TG+ KGYGFI +  ++ ++ A+  +N F+L
Sbjct: 257 LHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFEL 316

Query: 293 GGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPG 352
            G+ ++VG         +T  T           A++A++ + + E       LGT G   
Sbjct: 317 AGRPMKVGH--------VTERTD----------ASSASSFLDSDELERTGIDLGTTGRLQ 358

Query: 353 LVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGL 412
           L++  L     L   P A  A Q  G +     A     + + +                
Sbjct: 359 LMA-RLAEGTGLQIPPAAQQALQMSGSLAFGAVAEFSFVIDLQT---------------- 401

Query: 413 LEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDP 472
                                LS+Q   S   ++A        ++   +    L NM +P
Sbjct: 402 --------------------RLSQQTEASALAAAAS-------VQPLATQCFQLSNMFNP 434

Query: 473 K-----DIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHK 527
           +       D +++ +V EEC K G V  + IY +K   + +      ++V+    +    
Sbjct: 435 QTEEEVGWDTEIKDDVIEECNKHGGV--IHIYVDKNSAQGN------VYVKCPSIAAAIA 486

Query: 528 AIQALNGRWFAGRKVVA 544
           A+ AL+GRWFAG+ + A
Sbjct: 487 AVNALHGRWFAGKMITA 503


>gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens]
          Length = 524

 Score =  102 bits (253), Expect = 1e-21
 Identities = 99/437 (22%), Positives = 184/437 (42%), Gaps = 85/437 (19%)

Query: 113 PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGF 172
           P+ ++  + + A  + C      I        + + F+  G ++ + M  D  + + KG 
Sbjct: 141 PIDNLTPEERDARTVFCMQLAARIRPR----DLEEFFSTVGKVRDVRMISDRNSRRSKGI 196

Query: 173 AFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVAS 232
           A+VE+    +  LA+      +LG   I     +   +A  + + L + +    R+YV S
Sbjct: 197 AYVEFVDVSSVPLAIGLTGQRVLGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGS 256

Query: 233 VHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDL 292
           +H ++++D ++ +FE FG+I+S  L  D  TG+ KGYGFI +  ++ ++ A+  +N F+L
Sbjct: 257 LHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFEL 316

Query: 293 GGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPG 352
            G+ ++VG         +T  T           A++A++ + + E       LGT G   
Sbjct: 317 AGRPMKVGH--------VTERTD----------ASSASSFLDSDELERTGIDLGTTGRLQ 358

Query: 353 LVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGL 412
           L++  L     L   P A  A Q  G +               + G V            
Sbjct: 359 LMA-RLAEGTGLQIPPAAQQALQMSGSL---------------AFGAV------------ 390

Query: 413 LEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDP 472
                          ++    LS+Q   S   ++A        ++   +    L NM +P
Sbjct: 391 ---------------ADLQTRLSQQTEASALAAAAS-------VQPLATQCFQLSNMFNP 428

Query: 473 K-----DIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHK 527
           +       D +++ +V EEC K G V  + IY +K   + +      ++V+    +    
Sbjct: 429 QTEEEVGWDTEIKDDVIEECNKHGGV--IHIYVDKNSAQGN------VYVKCPSIAAAIA 480

Query: 528 AIQALNGRWFAGRKVVA 544
           A+ AL+GRWFAG+ + A
Sbjct: 481 AVNALHGRWFAGKMITA 497


>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
          Length = 636

 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 64/214 (29%), Positives = 115/214 (53%), Gaps = 11/214 (5%)

Query: 93  QQLTNLQMAAVTMGFGDPLS--PLQSMAAQRQRAL--AIMCRVYVGSIYYELGEDTIRQA 148
           QQ  + + A  TM F D +   P++ M +QR  +L  + +  +++ ++   +    +   
Sbjct: 60  QQPADAERALDTMNF-DVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDT 118

Query: 149 FAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNI 208
           F+ FG I S  +  D      KG+ FV +E  EAA+ A+E+MN ++L  R + VGR  + 
Sbjct: 119 FSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSR 176

Query: 209 GQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKG 268
            + +    +L   A+ F  +Y+ +  +D+ D+ +K +F  FG   S  +  D + GK KG
Sbjct: 177 KEREA---ELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDES-GKSKG 232

Query: 269 YGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 302
           +GF+ +E+ + +Q AV  MN  +L G+ + VG+A
Sbjct: 233 FGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRA 266



 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 47/174 (27%), Positives = 90/174 (51%), Gaps = 11/174 (6%)

Query: 128 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 187
           M  +YVG ++ ++ E  + + F+P GPI SI +  D +T +  G+A+V ++ P  A+ AL
Sbjct: 10  MASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69

Query: 188 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 247
           + MN  ++ G+ +++       Q  P +            I++ ++ + + +  +   F 
Sbjct: 70  DTMNFDVIKGKPVRI----MWSQRDPSL-----RKSGVGNIFIKNLDKSIDNKALYDTFS 120

Query: 248 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 301
           AFG I SC +  D      KGYGF+ +E  ++++ A+  MN   L  + + VG+
Sbjct: 121 AFGNILSCKVVCDENGS--KGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGR 172



 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 107/436 (24%), Positives = 170/436 (38%), Gaps = 112/436 (25%)

Query: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
           VY+ +   ++ ++ ++  F  FGP  S+ +  D  + K KGF FV +E  E AQ A+++M
Sbjct: 193 VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEM 251

Query: 191 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNR-------------IYVASVHQDL 237
           N   L G+ I VGR      AQ  +++  E  R F +             +YV ++   +
Sbjct: 252 NGKELNGKQIYVGR------AQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGI 305

Query: 238 SDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMN--------- 288
            D+ ++  F  FG I S  +  +   G+ KG+GF+ +   + +  AV+ MN         
Sbjct: 306 DDERLRKEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPL 363

Query: 289 -----------LFDLGGQYL-RVGKAVTPPMPLLT---PATPGG-----LP--------- 319
                         L  QY+ R+      P P++    PA P G     +P         
Sbjct: 364 YVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRAAYY 423

Query: 320 PAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGLVSPAL--------------------- 358
           P + +A    + + TAQ    GA        PG + PA                      
Sbjct: 424 PPSQIAQLRPSPRWTAQ----GARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMST 479

Query: 359 -----TLAQPLGTLPQAVMAAQAPGVIT--------GV------TPARPPIPVTIPSVGV 399
                T  Q +G  P A  AA  P V T        GV        A+P + +  P+V V
Sbjct: 480 QRVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHV 539

Query: 400 --VNPILASPPTLGLLEPKKEKEEEELFP--ESERPEMLSEQEHM--SISGSSARHMV-- 451
               P+ AS       + +K+   E LFP  ++  P +  +   M   I  S   HM+  
Sbjct: 540 QGQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLES 599

Query: 452 MQKLLRKQESTVMVLR 467
            + L  K +  V VL+
Sbjct: 600 PESLRSKVDEAVAVLQ 615



 Score = 30.4 bits (67), Expect = 4.5
 Identities = 21/86 (24%), Positives = 42/86 (48%), Gaps = 10/86 (11%)

Query: 457 RKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIF 516
           R +E T + ++N  +  D+DD+    + +  GKFG    V +  ++ G+ +        F
Sbjct: 186 RAKEFTNVYIKNFGE--DMDDE---RLKDLFGKFGPALSVKVMTDESGKSKGFG-----F 235

Query: 517 VEFSIASETHKAIQALNGRWFAGRKV 542
           V F    +  KA+  +NG+   G+++
Sbjct: 236 VSFERHEDAQKAVDEMNGKELNGKQI 261


>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
           sapiens]
          Length = 370

 Score = 95.5 bits (236), Expect = 1e-19
 Identities = 66/213 (30%), Positives = 113/213 (53%), Gaps = 11/213 (5%)

Query: 94  QLTNLQMAAVTMGFGDPLS--PLQSMAAQRQRAL--AIMCRVYVGSIYYELGEDTIRQAF 149
           QL + Q A  TM F D +    ++ M +QR   L  + +  V++ ++   +   T+ + F
Sbjct: 60  QLADAQKALDTMNF-DIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHF 118

Query: 150 APFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIG 209
           + FG I S  +  D      KG+AFV ++   AA  A+E+MN  +L G  + VGR  N  
Sbjct: 119 SAFGKILSSKVMSDD--QGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRK 176

Query: 210 QAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGY 269
             +    +L  +A  F  +Y+ +   D+ D+ +K VF  +GK  S  +  D ++GK KG+
Sbjct: 177 DREA---ELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTD-SSGKSKGF 232

Query: 270 GFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 302
           GF+ ++  ++++ AV  MN  D+ GQ + VG+A
Sbjct: 233 GFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRA 265



 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 46/179 (25%), Positives = 94/179 (52%), Gaps = 10/179 (5%)

Query: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
           VY+ +   ++ ++ ++  F+ +G   S+ +  DS + K KGF FV ++  EAA+ A+E+M
Sbjct: 192 VYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEEM 250

Query: 191 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFN-------RIYVASVHQDLSDDDIK 243
           N   + G+ I VGR     + Q  + Q+ E+ +          ++Y+ ++   + D+ ++
Sbjct: 251 NGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLR 310

Query: 244 SVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 302
           + F +FG I    + ++   G+ KG+G I +   + +  A++ MN   LG + L +  A
Sbjct: 311 NEFSSFGSISRVKVMQE--EGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALA 367



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 44/174 (25%), Positives = 84/174 (48%), Gaps = 11/174 (6%)

Query: 128 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 187
           M  +YVG ++ ++ ED + + F+  GP+ SI +  D VT +  G+A+V +     AQ AL
Sbjct: 9   MASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKAL 68

Query: 188 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 247
           + MN  ++ G++I++         +               +++ ++ + + +  +   F 
Sbjct: 69  DTMNFDIIKGKSIRLMWSQRDAYLR---------RSGIGNVFIKNLDKSIDNKTLYEHFS 119

Query: 248 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 301
           AFGKI S  +  D      KGY F+ ++   ++  A+  MN   L G  + VG+
Sbjct: 120 AFGKILSSKVMSDDQGS--KGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGR 171


>gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens]
          Length = 405

 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 76/277 (27%), Positives = 126/277 (45%), Gaps = 34/277 (12%)

Query: 113 PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGF 172
           P+ +++ + + A  + C      I     ED     F+  G ++ + +  D  + + KG 
Sbjct: 120 PVDNLSPEERDARTVFCMQLAARIRPRDLEDF----FSAVGKVRDVRIISDRNSRRSKGI 175

Query: 173 AFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVAS 232
           A+VE+   ++  LA+      +LG   I     +   +   + + L +      R+YV S
Sbjct: 176 AYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGS 235

Query: 233 VHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDL 292
           +H ++++D ++ +FE FGKI +  L +D  TG+ KGYGFI +  ++ ++ A+  +N F+L
Sbjct: 236 LHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFEL 295

Query: 293 GGQYLRVGKA---------VTPP-----------------MPLLTPATPGGLPPAAAVAA 326
            G+ +RVG           +T P                 M  L       LP  AA AA
Sbjct: 296 AGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEGAGIQLPSTAAAAA 355

Query: 327 AAATAKITAQEAVAGAAVLGTLGTPGL--VSPALTLA 361
           AAA      Q  + GA  LG L    L  +SPAL LA
Sbjct: 356 AAAAQAAALQ--LNGAVPLGALNPAALTALSPALNLA 390


>gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens]
          Length = 439

 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 76/277 (27%), Positives = 126/277 (45%), Gaps = 34/277 (12%)

Query: 113 PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGF 172
           P+ +++ + + A  + C      I     ED     F+  G ++ + +  D  + + KG 
Sbjct: 154 PVDNLSPEERDARTVFCMQLAARIRPRDLEDF----FSAVGKVRDVRIISDRNSRRSKGI 209

Query: 173 AFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVAS 232
           A+VE+   ++  LA+      +LG   I     +   +   + + L +      R+YV S
Sbjct: 210 AYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGS 269

Query: 233 VHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDL 292
           +H ++++D ++ +FE FGKI +  L +D  TG+ KGYGFI +  ++ ++ A+  +N F+L
Sbjct: 270 LHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFEL 329

Query: 293 GGQYLRVGKA---------VTPP-----------------MPLLTPATPGGLPPAAAVAA 326
            G+ +RVG           +T P                 M  L       LP  AA AA
Sbjct: 330 AGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEGAGIQLPSTAAAAA 389

Query: 327 AAATAKITAQEAVAGAAVLGTLGTPGL--VSPALTLA 361
           AAA      Q  + GA  LG L    L  +SPAL LA
Sbjct: 390 AAAAQAAALQ--LNGAVPLGALNPAALTALSPALNLA 424


>gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens]
          Length = 423

 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 76/277 (27%), Positives = 126/277 (45%), Gaps = 34/277 (12%)

Query: 113 PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGF 172
           P+ +++ + + A  + C      I     ED     F+  G ++ + +  D  + + KG 
Sbjct: 138 PVDNLSPEERDARTVFCMQLAARIRPRDLEDF----FSAVGKVRDVRIISDRNSRRSKGI 193

Query: 173 AFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVAS 232
           A+VE+   ++  LA+      +LG   I     +   +   + + L +      R+YV S
Sbjct: 194 AYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNGGPMRLYVGS 253

Query: 233 VHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDL 292
           +H ++++D ++ +FE FGKI +  L +D  TG+ KGYGFI +  ++ ++ A+  +N F+L
Sbjct: 254 LHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFEL 313

Query: 293 GGQYLRVGKA---------VTPP-----------------MPLLTPATPGGLPPAAAVAA 326
            G+ +RVG           +T P                 M  L       LP  AA AA
Sbjct: 314 AGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEGAGIQLPSTAAAAA 373

Query: 327 AAATAKITAQEAVAGAAVLGTLGTPGL--VSPALTLA 361
           AAA      Q  + GA  LG L    L  +SPAL LA
Sbjct: 374 AAAAQAAALQ--LNGAVPLGALNPAALTALSPALNLA 408


>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
          Length = 631

 Score = 93.6 bits (231), Expect = 4e-19
 Identities = 56/192 (29%), Positives = 106/192 (55%), Gaps = 8/192 (4%)

Query: 113 PLQSMAAQRQRAL--AIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHK 170
           P++ M +QR  +L  + +  ++V ++   +    +    + FG I S ++  D      K
Sbjct: 81  PVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFGNILSCNVVCDE--NGSK 138

Query: 171 GFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYV 230
           G+ FV +E  EAA+ A+++MN ++L GR + VG+  +  + +    +L   A+ F  +Y+
Sbjct: 139 GYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKEREA---ELGARAKEFPNVYI 195

Query: 231 ASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLF 290
            +  +D+ D+ +K +F  FG   S  +  D + GK KG+GF+ +E+ + +Q AV  MN  
Sbjct: 196 KNFGEDMDDERLKDLFGKFGPALSVKVMTDES-GKSKGFGFVSFERHEDAQKAVDEMNGK 254

Query: 291 DLGGQYLRVGKA 302
           +L G+ + VG+A
Sbjct: 255 ELNGKQIYVGRA 266



 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 49/171 (28%), Positives = 85/171 (49%), Gaps = 22/171 (12%)

Query: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
           VY+ +   ++ ++ ++  F  FGP  S+ +  D  + K KGF FV +E  E AQ A+++M
Sbjct: 193 VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEM 251

Query: 191 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNR-------------IYVASVHQDL 237
           N   L G+ I VGR      AQ  +++  E  R F +             +YV ++   +
Sbjct: 252 NGKELNGKQIYVGR------AQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGI 305

Query: 238 SDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMN 288
            D+ ++  F  FG I S  +  +   G+ KG+GF+ +   + +  AV+ MN
Sbjct: 306 DDERLRKAFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMN 354



 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 45/171 (26%), Positives = 88/171 (51%), Gaps = 11/171 (6%)

Query: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
           +YVG ++ ++ E  + + F+P GPI SI +  D +T     +A+V ++  + A+ AL+ M
Sbjct: 13  LYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTM 72

Query: 191 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 250
           N  ++ G+ +++       Q  P +            I+V ++ + +++  +     AFG
Sbjct: 73  NFDVIKGKPVRI----MWSQRDPSL-----RKSGVGNIFVKNLDKSINNKALYDTVSAFG 123

Query: 251 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 301
            I SC +  D      KGYGF+ +E  ++++ A+  MN   L G+ + VG+
Sbjct: 124 NILSCNVVCDENGS--KGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQ 172



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 22/72 (30%), Positives = 41/72 (56%), Gaps = 2/72 (2%)

Query: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
           +YV ++   + ++ +R+AF+PFG I S  +  +    + KGF FV +  PE A  A+ +M
Sbjct: 296 LYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEGG--RSKGFGFVCFSSPEEATKAVTEM 353

Query: 191 NSVMLGGRNIKV 202
           N  ++  + + V
Sbjct: 354 NGRIVATKPLYV 365



 Score = 29.3 bits (64), Expect = 10.0
 Identities = 17/71 (23%), Positives = 35/71 (49%), Gaps = 6/71 (8%)

Query: 473 KDIDDDLEGEVTEEC-GKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQA 531
           K+  +D++ E  ++  GKFG    V +  ++ G+ +        FV F    +  KA+  
Sbjct: 196 KNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFG-----FVSFERHEDAQKAVDE 250

Query: 532 LNGRWFAGRKV 542
           +NG+   G+++
Sbjct: 251 MNGKELNGKQI 261


>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
           sapiens]
          Length = 614

 Score = 90.5 bits (223), Expect = 4e-18
 Identities = 79/267 (29%), Positives = 134/267 (50%), Gaps = 27/267 (10%)

Query: 52  AKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQ---------QQLTNLQMAA 102
           A L +  L P+  EA+   +K++    I S+ V + +A ++         QQ  + + A 
Sbjct: 11  ASLYVGDLHPDVTEAMLY-EKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERAL 69

Query: 103 VTMGFGDPLS--PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQ-----AFAPFGPI 155
            TM F + L   P++ M +QR   L    +  VG+I+ +  ED+I        F+ FG I
Sbjct: 70  DTMNF-EMLKGQPIRIMWSQRDPGLR---KSGVGNIFIKNLEDSIDNKALYDTFSTFGNI 125

Query: 156 KSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPII 215
            S  ++ D      +GF FV +E  EAAQ A+  MN ++L  R + VG   +  + +   
Sbjct: 126 LSCKVACDE--HGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRREREA-- 181

Query: 216 DQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYE 275
            +L   A  F  IYV ++  D+ +  ++ +F  FGK+ S  + RD  +G  + +GF+ +E
Sbjct: 182 -ELGARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRD-NSGHSRCFGFVNFE 239

Query: 276 KAQSSQDAVSSMNLFDLGGQYLRVGKA 302
           K + +Q AV  MN  ++ G+ L  G+A
Sbjct: 240 KHEEAQKAVVHMNGKEVSGRLLYAGRA 266



 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 47/173 (27%), Positives = 89/173 (51%), Gaps = 11/173 (6%)

Query: 128 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 187
           +  +YVG ++ ++ E  + + F+P GPI SI +  D  T +  G+A++ ++ P  A+ AL
Sbjct: 10  LASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERAL 69

Query: 188 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 247
           + MN  ML G+ I++       Q  P +            I++ ++   + +  +   F 
Sbjct: 70  DTMNFEMLKGQPIRI----MWSQRDPGL-----RKSGVGNIFIKNLEDSIDNKALYDTFS 120

Query: 248 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVG 300
            FG I SC +A D      +G+GF+ +E  +++Q A+++MN   L  + + VG
Sbjct: 121 TFGNILSCKVACDEHGS--RGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVG 171



 Score = 63.5 bits (153), Expect = 5e-10
 Identities = 48/180 (26%), Positives = 87/180 (48%), Gaps = 12/180 (6%)

Query: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
           +YV ++  ++ E  ++  F+ FG + S+ +  D+ +   + F FV +E  E AQ A+  M
Sbjct: 193 IYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVVHM 251

Query: 191 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFN-------RIYVASVHQDLSDDDIK 243
           N   + GR +  GR     + Q  + +  E+ +           +YV ++   + DD ++
Sbjct: 252 NGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLR 311

Query: 244 SVFEAFGKIKSCTLARDPTTGKH-KGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 302
             F  +G I S   A+  T G H KG+GF+ +   + +  AV+ MN   +G + L V  A
Sbjct: 312 KEFSPYGVITS---AKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALA 368


>gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Homo
           sapiens]
          Length = 200

 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 51/174 (29%), Positives = 94/174 (54%), Gaps = 11/174 (6%)

Query: 128 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 187
           M  +YVG ++ E+ E  + + F+P GPI SI +  D +T +  G+A+V Y+ P  A+ AL
Sbjct: 1   MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60

Query: 188 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 247
           E +N  ++ GR +++       Q  P +            +++ ++ + + +  + ++F 
Sbjct: 61  ETLNFDVIKGRPVRI----MWSQRDPSL-----RKSGVGNVFIKNLGKTIDNKALYNIFS 111

Query: 248 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 301
           AFG I SC +A D      KGYGF+ ++K +S++ A+  MN   L  + + VG+
Sbjct: 112 AFGNILSCKVACDEK--GPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGR 163


>gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo
           sapiens]
          Length = 200

 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 51/174 (29%), Positives = 94/174 (54%), Gaps = 11/174 (6%)

Query: 128 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 187
           M  +YVG ++ E+ E  + + F+P GPI SI +  D +T +  G+A+V Y+ P  A+ AL
Sbjct: 1   MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60

Query: 188 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 247
           E +N  ++ GR +++       Q  P +            +++ ++ + + +  + ++F 
Sbjct: 61  ETLNFDVIKGRPVRI----MWSQRDPSL-----RKSGVGNVFIKNLGKTIDNKALYNIFS 111

Query: 248 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 301
           AFG I SC +A D      KGYGF+ ++K +S++ A+  MN   L  + + VG+
Sbjct: 112 AFGNILSCKVACDEK--GPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGR 163


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 85.9 bits (211), Expect = 9e-17
 Identities = 86/334 (25%), Positives = 135/334 (40%), Gaps = 53/334 (15%)

Query: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
           VYVG +  ++ E  + + F   GP+ +  M  D VT +H+G+ FVE+   E A  A++ M
Sbjct: 15  VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIM 74

Query: 191 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 250
           N + L G+ I+V + S   +   +             I++ ++  ++ +  +   F AFG
Sbjct: 75  NMIKLYGKPIRVNKASAHNKNLDV----------GANIFIGNLDPEIDEKLLYDTFSAFG 124

Query: 251 KI-KSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYL------------ 297
            I ++  + RDP TG  KGY FI +    +S  A+ +MN     GQYL            
Sbjct: 125 VILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMN-----GQYLCNRPITVSYAFK 179

Query: 298 ------RVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTP 351
                 R G A    +    P +    P      A    +        A   V+ +LG+ 
Sbjct: 180 KDSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPS--------APNPVVSSLGS- 230

Query: 352 GLVSPALTLAQPLGTLPQAVMAAQAPGVI-TGVTPARPPIPVTIPSVGVVNPILASPPTL 410
           GL  P +    P G+ P  V     PG +  G+ PA PP P+   + G   P   +P   
Sbjct: 231 GLPPPGM---PPPGSFPPPV---PPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTP--- 281

Query: 411 GLLEPKKEKEEEELFPESERPEMLSEQEHMSISG 444
           G   P         FP    P     Q  ++  G
Sbjct: 282 GAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHG 315



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 26/97 (26%), Positives = 49/97 (50%), Gaps = 3/97 (3%)

Query: 107 FGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPI-KSIDMSWDSV 165
           +G P+    + A+   + L +   +++G++  E+ E  +   F+ FG I ++  +  D  
Sbjct: 80  YGKPIRV--NKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPD 137

Query: 166 TMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKV 202
           T   KG+AF+ +   +A+  A+E MN   L  R I V
Sbjct: 138 TGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITV 174


>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
          Length = 375

 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 55/182 (30%), Positives = 90/182 (49%), Gaps = 10/182 (5%)

Query: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
           +YVG++  ++ E  I Q F+  GP K+  M  D  T  +  + FVE+     A  AL  M
Sbjct: 9   LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAAM 66

Query: 191 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 250
           N   + G+ +KV        A     Q  + +  F+ ++V  +  +++ +DIK+ F  FG
Sbjct: 67  NGRKIMGKEVKVN------WATTPSSQKKDTSNHFH-VFVGDLSPEITTEDIKAAFAPFG 119

Query: 251 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAV-TPPMPL 309
           +I    + +D  TGK KGYGF+ +     +++A+  M    LGG+ +R   A   PP P 
Sbjct: 120 RISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPK 179

Query: 310 LT 311
            T
Sbjct: 180 ST 181



 Score = 69.3 bits (168), Expect = 9e-12
 Identities = 49/179 (27%), Positives = 82/179 (45%), Gaps = 17/179 (9%)

Query: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
           V+VG +  E+  + I+ AFAPFG I    +  D  T K KG+ FV +     A+ A++QM
Sbjct: 97  VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 156

Query: 191 NSVMLGGRNIKVGRPSNIGQA----------QPIIDQLAEEARAFN-RIYVASVHQDLSD 239
               LGGR I+    +    A          Q   D++  ++   N  +Y   V   L++
Sbjct: 157 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 216

Query: 240 DDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLR 298
             ++  F  FG+I    +  D      KGY F+ +   +S+  A+ S+N   + G  ++
Sbjct: 217 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVK 269



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 6/73 (8%)

Query: 129 CRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALE 188
           C VY G +   L E  +RQ F+PFG I  I +  D      KG++FV +   E+A  A+ 
Sbjct: 203 CTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIV 256

Query: 189 QMNSVMLGGRNIK 201
            +N   + G  +K
Sbjct: 257 SVNGTTIEGHVVK 269


>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
          Length = 382

 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 58/200 (29%), Positives = 101/200 (50%), Gaps = 22/200 (11%)

Query: 113 PLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGF 172
           P +  A  R R  A    V+V +I  ++ ++ +++ F  +GP +S+ +  D+ + K KGF
Sbjct: 183 PEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA-SGKSKGF 241

Query: 173 AFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNR----- 227
            FV YE  EAAQ A+  ++   + G+ + VGR      AQ  I++LAE  R F R     
Sbjct: 242 GFVRYETHEAAQKAVLDLHGKSIDGKVLYVGR------AQKKIERLAELRRRFERLRLKE 295

Query: 228 --------IYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQS 279
                   IY+ ++ + ++D+ +K  F +FG I    +  +   G+ KG+G + +   + 
Sbjct: 296 KSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEE 353

Query: 280 SQDAVSSMNLFDLGGQYLRV 299
           +  AV  MN   +G + L V
Sbjct: 354 ATKAVDEMNGRIVGSKPLHV 373



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 56/208 (26%), Positives = 99/208 (47%), Gaps = 10/208 (4%)

Query: 99  QMAAVTMGF----GDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGP 154
           + A  TM F    G P   + S    R R   +   +++ ++   +    +   F+ FG 
Sbjct: 73  EWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVG-NIFIKNLDKSIDNRALFYLFSAFGN 131

Query: 155 IKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPI 214
           I S  +  D      KG+A+V ++   AA  A+  MN V L  R + VGR       +  
Sbjct: 132 ILSCKVVCDD--NGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKF--PEERA 187

Query: 215 IDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEY 274
            +    +   F  ++V ++  D+ D+ +K +F  +G  +S  + RD  +GK KG+GF+ Y
Sbjct: 188 AEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRD-ASGKSKGFGFVRY 246

Query: 275 EKAQSSQDAVSSMNLFDLGGQYLRVGKA 302
           E  +++Q AV  ++   + G+ L VG+A
Sbjct: 247 ETHEAAQKAVLDLHGKSIDGKVLYVGRA 274



 Score = 70.1 bits (170), Expect = 5e-12
 Identities = 51/201 (25%), Positives = 97/201 (48%), Gaps = 18/201 (8%)

Query: 105 MGFGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDS 164
           MG G+P     + A ++++ L     +YVG +  ++ ED + + F P GP++   +  D 
Sbjct: 1   MGSGEP-----NPAGKKKKYLK--AALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDP 53

Query: 165 VTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARA 224
           VT    G+ +V +  P  A+ AL  MN  ++       G+P  +  +QP  D+L +    
Sbjct: 54  VTRSPLGYGYVNFRFPADAEWALNTMNFDLIN------GKPFRLMWSQP-DDRLRKS--G 104

Query: 225 FNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAV 284
              I++ ++ + + +  +  +F AFG I SC +  D      KGY ++ ++   ++  A+
Sbjct: 105 VGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGS--KGYAYVHFDSLAAANRAI 162

Query: 285 SSMNLFDLGGQYLRVGKAVTP 305
             MN   L  + + VG+   P
Sbjct: 163 WHMNGVRLNNRQVYVGRFKFP 183


>gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]
          Length = 375

 Score = 83.2 bits (204), Expect = 6e-16
 Identities = 56/182 (30%), Positives = 90/182 (49%), Gaps = 10/182 (5%)

Query: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
           +YVG++  ++ E  I Q F+  GP KS  M  +  +  +  + FVE+     A  AL  M
Sbjct: 11  LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTS--NDPYCFVEFYEHRDAAAALAAM 68

Query: 191 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 250
           N   + G+ +KV        A     Q  + +  F+ ++V  +  +++ +DIKS F  FG
Sbjct: 69  NGRKILGKEVKVN------WATTPSSQKKDTSNHFH-VFVGDLSPEITTEDIKSAFAPFG 121

Query: 251 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAV-TPPMPL 309
           KI    + +D  TGK KGYGF+ +     +++A+  M    LGG+ +R   A   PP P 
Sbjct: 122 KISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPK 181

Query: 310 LT 311
            T
Sbjct: 182 ST 183



 Score = 63.5 bits (153), Expect = 5e-10
 Identities = 46/179 (25%), Positives = 79/179 (44%), Gaps = 17/179 (9%)

Query: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
           V+VG +  E+  + I+ AFAPFG I    +  D  T K KG+ FV +     A+ A+  M
Sbjct: 99  VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 158

Query: 191 NSVMLGGRNIKVGRPSNIGQA----------QPIIDQLAEEARAFN-RIYVASVHQDLSD 239
               LGGR I+    +    A          Q   + +  ++   N  +Y   +   L+D
Sbjct: 159 GGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTD 218

Query: 240 DDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLR 298
             ++  F  FG+I    +  +      KGY F+ +   +S+  A+ S+N   + G  ++
Sbjct: 219 QLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAIVSVNGTTIEGHVVK 271



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 6/73 (8%)

Query: 129 CRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALE 188
           C VY G I   L +  +RQ F+PFG I  I +         KG++FV +   E+A  A+ 
Sbjct: 205 CTVYCGGIASGLTDQLMRQTFSPFGQIMEIRV------FPEKGYSFVRFSTHESAAHAIV 258

Query: 189 QMNSVMLGGRNIK 201
            +N   + G  +K
Sbjct: 259 SVNGTTIEGHVVK 271


>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
          Length = 386

 Score = 82.8 bits (203), Expect = 8e-16
 Identities = 52/186 (27%), Positives = 89/186 (47%), Gaps = 7/186 (3%)

Query: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
           +YVG++  ++ E  I Q F+  GP K+  M  D  T  +  + FVE+     A  AL  M
Sbjct: 9   LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAAM 66

Query: 191 NSVMLGGRNIKVGRPSNIGQAQPIIDQLA----EEARAFNRIYVASVHQDLSDDDIKSVF 246
           N   + G+ +KV   +     +           + ++    ++V  +  +++ +DIK+ F
Sbjct: 67  NGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAF 126

Query: 247 EAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAV-TP 305
             FG+I    + +D  TGK KGYGF+ +     +++A+  M    LGG+ +R   A   P
Sbjct: 127 APFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKP 186

Query: 306 PMPLLT 311
           P P  T
Sbjct: 187 PAPKST 192



 Score = 69.3 bits (168), Expect = 9e-12
 Identities = 49/179 (27%), Positives = 82/179 (45%), Gaps = 17/179 (9%)

Query: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
           V+VG +  E+  + I+ AFAPFG I    +  D  T K KG+ FV +     A+ A++QM
Sbjct: 108 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 167

Query: 191 NSVMLGGRNIKVGRPSNIGQA----------QPIIDQLAEEARAFN-RIYVASVHQDLSD 239
               LGGR I+    +    A          Q   D++  ++   N  +Y   V   L++
Sbjct: 168 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 227

Query: 240 DDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLR 298
             ++  F  FG+I    +  D      KGY F+ +   +S+  A+ S+N   + G  ++
Sbjct: 228 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVK 280



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 6/73 (8%)

Query: 129 CRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALE 188
           C VY G +   L E  +RQ F+PFG I  I +  D      KG++FV +   E+A  A+ 
Sbjct: 214 CTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIV 267

Query: 189 QMNSVMLGGRNIK 201
            +N   + G  +K
Sbjct: 268 SVNGTTIEGHVVK 280


>gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]
          Length = 392

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 57/197 (28%), Positives = 91/197 (46%), Gaps = 23/197 (11%)

Query: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSV------------TMKHKG---FAFV 175
           +YVG++  ++ E  I Q F+  GP KS  M  +               ++H     + FV
Sbjct: 11  LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCFV 70

Query: 176 EYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQ 235
           E+     A  AL  MN   + G+ +KV        A     Q  + +  F+ ++V  +  
Sbjct: 71  EFYEHRDAAAALAAMNGRKILGKEVKVN------WATTPSSQKKDTSNHFH-VFVGDLSP 123

Query: 236 DLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQ 295
           +++ +DIKS F  FGKI    + +D  TGK KGYGF+ +     +++A+  M    LGG+
Sbjct: 124 EITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGR 183

Query: 296 YLRVGKAV-TPPMPLLT 311
            +R   A   PP P  T
Sbjct: 184 QIRTNWATRKPPAPKST 200



 Score = 63.5 bits (153), Expect = 5e-10
 Identities = 46/179 (25%), Positives = 79/179 (44%), Gaps = 17/179 (9%)

Query: 131 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 190
           V+VG +  E+  + I+ AFAPFG I    +  D  T K KG+ FV +     A+ A+  M
Sbjct: 116 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 175

Query: 191 NSVMLGGRNIKVGRPSNIGQA----------QPIIDQLAEEARAFN-RIYVASVHQDLSD 239
               LGGR I+    +    A          Q   + +  ++   N  +Y   +   L+D
Sbjct: 176 GGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTD 235

Query: 240 DDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLR 298
             ++  F  FG+I    +  +      KGY F+ +   +S+  A+ S+N   + G  ++
Sbjct: 236 QLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAIVSVNGTTIEGHVVK 288



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 6/73 (8%)

Query: 129 CRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALE 188
           C VY G I   L +  +RQ F+PFG I  I +         KG++FV +   E+A  A+ 
Sbjct: 222 CTVYCGGIASGLTDQLMRQTFSPFGQIMEIRV------FPEKGYSFVRFSTHESAAHAIV 275

Query: 189 QMNSVMLGGRNIK 201
            +N   + G  +K
Sbjct: 276 SVNGTTIEGHVVK 288


>gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo
           sapiens]
          Length = 486

 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 76/296 (25%), Positives = 126/296 (42%), Gaps = 21/296 (7%)

Query: 130 RVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAA---QLA 186
           ++++G I   L E  ++  F  FG I  + +  D  T  HKG AF+ Y   E+A   Q A
Sbjct: 55  KLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSA 114

Query: 187 LEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVF 246
           L +  ++    R I+V +P++  +++     L +      +++V  +++  S+DD++ +F
Sbjct: 115 LHEQKTLPGMNRPIQV-KPAD-SESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLF 172

Query: 247 EAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMN--------LFDLGGQYLR 298
           EAFG I+ CT+ R P  G  KG  F++Y     +Q A+++++           L  ++  
Sbjct: 173 EAFGNIEECTILRGP-DGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFAD 231

Query: 299 VGKAVTPPMPLLTPATPGGLPPAA---AVAAAAATAKITAQEAVAGAAVLGTLGTPGLVS 355
             K  T           G   P A       A A A +  Q A+  +   G    P    
Sbjct: 232 TDKERTMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAF 291

Query: 356 PALTLAQPLGTLPQAVMAAQAPGVITGVTP---ARPPIPVTIPSVGVVNPILASPP 408
            A  + Q        + AA       G TP     P +P +IPS   VN     PP
Sbjct: 292 AAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVP-SIPSPIGVNGFTGLPP 346



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 20/86 (23%)

Query: 117 MAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVE 176
           M  Q+QR     C +++  +  E G+  + Q F PFG                    FV 
Sbjct: 409 MIPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLPFG--------------------FVS 448

Query: 177 YEVPEAAQLALEQMNSVMLGGRNIKV 202
           ++ P +AQ A++ MN   +G + +KV
Sbjct: 449 FDNPASAQTAIQAMNGFQIGMKRLKV 474



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 20/90 (22%), Positives = 38/90 (42%), Gaps = 20/90 (22%)

Query: 210 QAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGY 269
           Q  P+I Q   E      +++  + Q+  D ++  +F  FG                   
Sbjct: 405 QPPPMIPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLPFG------------------- 445

Query: 270 GFIEYEKAQSSQDAVSSMNLFDLGGQYLRV 299
            F+ ++   S+Q A+ +MN F +G + L+V
Sbjct: 446 -FVSFDNPASAQTAIQAMNGFQIGMKRLKV 474


>gi|20373175 musashi 2 isoform a [Homo sapiens]
          Length = 328

 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 52/195 (26%), Positives = 94/195 (48%), Gaps = 17/195 (8%)

Query: 130 RVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQ 189
           ++++G + ++   D++R  F+ FG I+   +  D  T + +GF FV +  P +    L Q
Sbjct: 22  KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 81

Query: 190 MNSVMLGGRNI--KVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 247
            +   L  + I  KV  P    +AQP      +      +I+V  +  +   +D+K  FE
Sbjct: 82  PHHE-LDSKTIDPKVAFPR---RAQP------KMVTRTKKIFVGGLSANTVVEDVKQYFE 131

Query: 248 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPM 307
            FGK++   L  D TT +H+G+GF+ +E  +   + V  ++  ++  + +   KA  P  
Sbjct: 132 QFGKVEDAMLMFDKTTNRHRGFGFVTFEN-EDVVEKVCEIHFHEINNKMVECKKA-QPKE 189

Query: 308 PLLTPATPG---GLP 319
            +  P T G   GLP
Sbjct: 190 VMFPPGTRGRARGLP 204


>gi|25121993 musashi 2 isoform b [Homo sapiens]
          Length = 251

 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 52/195 (26%), Positives = 94/195 (48%), Gaps = 17/195 (8%)

Query: 130 RVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQ 189
           ++++G + ++   D++R  F+ FG I+   +  D  T + +GF FV +  P +    L Q
Sbjct: 18  KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 77

Query: 190 MNSVMLGGRNI--KVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 247
            +   L  + I  KV  P    +AQP      +      +I+V  +  +   +D+K  FE
Sbjct: 78  PHHE-LDSKTIDPKVAFPR---RAQP------KMVTRTKKIFVGGLSANTVVEDVKQYFE 127

Query: 248 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPM 307
            FGK++   L  D TT +H+G+GF+ +E  +   + V  ++  ++  + +   KA  P  
Sbjct: 128 QFGKVEDAMLMFDKTTNRHRGFGFVTFEN-EDVVEKVCEIHFHEINNKMVECKKA-QPKE 185

Query: 308 PLLTPATPG---GLP 319
            +  P T G   GLP
Sbjct: 186 VMFPPGTRGRARGLP 200



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 15/49 (30%), Positives = 31/49 (63%)

Query: 226 NRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEY 274
           +++++  +    S D ++  F  FG+I+ C + RDPTT + +G+GF+ +
Sbjct: 17  SKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTF 65


>gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo
           sapiens]
          Length = 448

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 78/296 (26%), Positives = 122/296 (41%), Gaps = 31/296 (10%)

Query: 130 RVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAA---QLA 186
           ++++G I   L E  ++  F  FG I  + +  D  T  HKG AF+ Y   E+A   Q A
Sbjct: 55  KLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSA 114

Query: 187 LEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVF 246
           L +  +  L G N  +       Q +P   +   E R   +++V  +++  S+DD++ +F
Sbjct: 115 LHEQKT--LPGMNRPI-------QVKPADSESRGEDR---KLFVGMLNKQQSEDDVRRLF 162

Query: 247 EAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMN--------LFDLGGQYLR 298
           EAFG I+ CT+ R P  G  KG  F++Y     +Q A+++++           L  ++  
Sbjct: 163 EAFGNIEECTILRGP-DGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFAD 221

Query: 299 VGKAVTPPMPLLTPATPGGLPPAA---AVAAAAATAKITAQEAVAGAAVLGTLGTPGLVS 355
             K  T           G   P A       A A A +  Q A+  +   G    P    
Sbjct: 222 TDKERTMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAF 281

Query: 356 PALTLAQPLGTLPQAVMAAQAPGVITGVTP---ARPPIPVTIPSVGVVNPILASPP 408
            A  + Q        + AA       G TP     P +P +IPS   VN     PP
Sbjct: 282 AAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVP-SIPSPIGVNGFTGLPP 336



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 15/52 (28%), Positives = 28/52 (53%)

Query: 248 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRV 299
           A+G+I        P   + +  GF+ ++   S+Q A+ +MN F +G + L+V
Sbjct: 385 AYGQISQAFPQPPPMIPQQQREGFVSFDNPASAQTAIQAMNGFQIGMKRLKV 436



 Score = 30.0 bits (66), Expect = 5.8
 Identities = 44/187 (23%), Positives = 66/187 (35%), Gaps = 14/187 (7%)

Query: 19  EPAAAAAVVAAGDKWKPPQGTDSIKMENGQSTAAK-LGLPPLTPEQQEALQKAKKYAMEQ 77
           + AA  A VA G    P     + +M+   +     L   P+TP    +           
Sbjct: 261 QQAALMASVAQGGYLNPMAAFAAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVP 320

Query: 78  SIKSVLVKQTIAHQQQQLTNLQMAAVTMGFGDPLSPLQSMAAQR--QRALAIMCRVYVGS 135
           SI S +          Q      A      G    P QS  A    Q+A A + + Y G 
Sbjct: 321 SIPSPIGVNGFTGLPPQANGQPAAEAVFANGIHPYPAQSPTAADPLQQAYAGV-QQYAGP 379

Query: 136 IYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVML 195
             Y      I QAF    P+            + +   FV ++ P +AQ A++ MN   +
Sbjct: 380 AAYPAAYGQISQAFPQPPPM----------IPQQQREGFVSFDNPASAQTAIQAMNGFQI 429

Query: 196 GGRNIKV 202
           G + +KV
Sbjct: 430 GMKRLKV 436


>gi|187761299 bruno-like 4, RNA binding protein isoform 2 [Homo
           sapiens]
          Length = 485

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 47/162 (29%), Positives = 88/162 (54%), Gaps = 6/162 (3%)

Query: 130 RVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAA---QLA 186
           ++++G I   L E  ++  F  FG I  + +  D  T  HKG AF+ Y   E+A   Q A
Sbjct: 55  KLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSA 114

Query: 187 LEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVF 246
           L +  ++    R I+V +P++  +++     L +      +++V  +++  S+DD++ +F
Sbjct: 115 LHEQKTLPGMNRPIQV-KPAD-SESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLF 172

Query: 247 EAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMN 288
           EAFG I+ CT+ R P  G  KG  F++Y     +Q A+++++
Sbjct: 173 EAFGNIEECTILRGP-DGNSKGCAFVKYSSHAEAQAAINALH 213



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 23/86 (26%), Positives = 38/86 (44%), Gaps = 20/86 (23%)

Query: 117 MAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVE 176
           M  Q+QR     C +++  +  E G+  + Q F PFG                    FV 
Sbjct: 408 MIPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLPFG--------------------FVS 447

Query: 177 YEVPEAAQLALEQMNSVMLGGRNIKV 202
           ++ P +AQ A++ MN   +G + +KV
Sbjct: 448 FDNPASAQTAIQAMNGFQIGMKRLKV 473



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 20/90 (22%), Positives = 38/90 (42%), Gaps = 20/90 (22%)

Query: 210 QAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGY 269
           Q  P+I Q   E      +++  + Q+  D ++  +F  FG                   
Sbjct: 404 QPPPMIPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLPFG------------------- 444

Query: 270 GFIEYEKAQSSQDAVSSMNLFDLGGQYLRV 299
            F+ ++   S+Q A+ +MN F +G + L+V
Sbjct: 445 -FVSFDNPASAQTAIQAMNGFQIGMKRLKV 473


>gi|224549005 RNA binding motif protein 17 [Homo sapiens]
          Length = 401

 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 40/101 (39%), Positives = 62/101 (61%), Gaps = 3/101 (2%)

Query: 458 KQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFV 517
           K  + V++LRNMV   ++D+DLE E  EEC K+G V + +I++     +++A   V+IF+
Sbjct: 301 KCPTKVVLLRNMVGAGEVDEDLEVETKEECEKYGKVGKCVIFEIPGAPDDEA---VRIFL 357

Query: 518 EFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLS 558
           EF       KA+  LNGR+F GR V A  Y+ ++F   DL+
Sbjct: 358 EFERVESAIKAVVDLNGRYFGGRVVKACFYNLDKFRVLDLA 398



 Score = 30.0 bits (66), Expect = 5.8
 Identities = 19/74 (25%), Positives = 36/74 (48%), Gaps = 2/74 (2%)

Query: 226 NRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYG-FIEYEKAQSSQDAV 284
           N +    V +DL + + K   E +GK+  C +   P     +    F+E+E+ +S+  AV
Sbjct: 311 NMVGAGEVDEDL-EVETKEECEKYGKVGKCVIFEIPGAPDDEAVRIFLEFERVESAIKAV 369

Query: 285 SSMNLFDLGGQYLR 298
             +N    GG+ ++
Sbjct: 370 VDLNGRYFGGRVVK 383


>gi|14249678 RNA binding motif protein 17 [Homo sapiens]
          Length = 401

 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 40/101 (39%), Positives = 62/101 (61%), Gaps = 3/101 (2%)

Query: 458 KQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFV 517
           K  + V++LRNMV   ++D+DLE E  EEC K+G V + +I++     +++A   V+IF+
Sbjct: 301 KCPTKVVLLRNMVGAGEVDEDLEVETKEECEKYGKVGKCVIFEIPGAPDDEA---VRIFL 357

Query: 518 EFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLS 558
           EF       KA+  LNGR+F GR V A  Y+ ++F   DL+
Sbjct: 358 EFERVESAIKAVVDLNGRYFGGRVVKACFYNLDKFRVLDLA 398



 Score = 30.0 bits (66), Expect = 5.8
 Identities = 19/74 (25%), Positives = 36/74 (48%), Gaps = 2/74 (2%)

Query: 226 NRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYG-FIEYEKAQSSQDAV 284
           N +    V +DL + + K   E +GK+  C +   P     +    F+E+E+ +S+  AV
Sbjct: 311 NMVGAGEVDEDL-EVETKEECEKYGKVGKCVIFEIPGAPDDEAVRIFLEFERVESAIKAV 369

Query: 285 SSMNLFDLGGQYLR 298
             +N    GG+ ++
Sbjct: 370 VDLNGRYFGGRVVK 383


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.130    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,554,190
Number of Sequences: 37866
Number of extensions: 1052677
Number of successful extensions: 7692
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 275
Number of HSP's successfully gapped in prelim test: 375
Number of HSP's that attempted gapping in prelim test: 5609
Number of HSP's gapped (non-prelim): 1829
length of query: 559
length of database: 18,247,518
effective HSP length: 107
effective length of query: 452
effective length of database: 14,195,856
effective search space: 6416526912
effective search space used: 6416526912
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.