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Search of human proteins with 17978477
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|17978477 vacuolar protein sorting 11 [Homo sapiens]
(941 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|17978477 vacuolar protein sorting 11 [Homo sapiens] 1917 0.0
gi|17978485 vacuolar protein sorting 18 [Homo sapiens] 62 2e-09
gi|114199473 vacuolar protein sorting 41 isoform 2 [Homo sapiens] 48 5e-05
gi|114199475 vacuolar protein sorting 41 isoform 1 [Homo sapiens] 48 5e-05
gi|21071001 autocrine motility factor receptor [Homo sapiens] 42 0.003
gi|49640011 tetratricopeptide repeat domain 3 [Homo sapiens] 40 0.010
gi|49640009 tetratricopeptide repeat domain 3 [Homo sapiens] 40 0.010
gi|27436927 synoviolin 1 isoform b [Homo sapiens] 38 0.051
gi|27436925 synoviolin 1 isoform a [Homo sapiens] 38 0.051
gi|40805104 topoisomerase I binding, arginine/serine-rich [Homo ... 38 0.051
gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens] 37 0.066
gi|37655169 ring finger protein 135 isoform 2 [Homo sapiens] 37 0.087
gi|37655167 ring finger protein 135 isoform 1 [Homo sapiens] 37 0.087
gi|21389505 janus kinase and microtubule interacting protein 1 i... 37 0.087
gi|150456473 janus kinase and microtubule interacting protein 1 ... 37 0.087
gi|30348954 mindbomb homolog 1 [Homo sapiens] 37 0.087
gi|239048909 checkpoint with forkhead and ring finger domains is... 36 0.15
gi|239048905 checkpoint with forkhead and ring finger domains is... 36 0.15
gi|239048862 checkpoint with forkhead and ring finger domains is... 36 0.15
gi|239048792 checkpoint with forkhead and ring finger domains is... 36 0.15
gi|239048907 checkpoint with forkhead and ring finger domains is... 36 0.15
gi|114155158 Ras association (RalGDS/AF-6) domain family (N-term... 36 0.15
gi|8051636 tRNA exportin [Homo sapiens] 36 0.15
gi|22027627 TNF receptor-associated factor 5 [Homo sapiens] 35 0.25
gi|77404348 TNF receptor-associated factor 5 [Homo sapiens] 35 0.25
gi|11321603 TNF receptor-associated factor 5 [Homo sapiens] 35 0.25
gi|13569903 ring finger protein 32 [Homo sapiens] 35 0.33
gi|157266273 RANBP2-like and GRIP domain containing 1 [Homo sapi... 34 0.56
gi|7662244 DAZ interacting protein 3, zinc finger [Homo sapiens] 34 0.56
gi|14149631 ring finger protein 112 [Homo sapiens] 34 0.56
>gi|17978477 vacuolar protein sorting 11 [Homo sapiens]
Length = 941
Score = 1917 bits (4967), Expect = 0.0
Identities = 941/941 (100%), Positives = 941/941 (100%)
Query: 1 MAAYLQWRRFVFFDKELVKEPLSNDGAAPGATPASGSAASKFLCLPPGITVCDSGRGSLV 60
MAAYLQWRRFVFFDKELVKEPLSNDGAAPGATPASGSAASKFLCLPPGITVCDSGRGSLV
Sbjct: 1 MAAYLQWRRFVFFDKELVKEPLSNDGAAPGATPASGSAASKFLCLPPGITVCDSGRGSLV 60
Query: 61 FGDMEGQIWFLPRSLQLTGFQAYKLRVTHLYQLKQHNILASVGEDEEGINPLVKIWNLEK 120
FGDMEGQIWFLPRSLQLTGFQAYKLRVTHLYQLKQHNILASVGEDEEGINPLVKIWNLEK
Sbjct: 61 FGDMEGQIWFLPRSLQLTGFQAYKLRVTHLYQLKQHNILASVGEDEEGINPLVKIWNLEK 120
Query: 121 RDGGNPLCTRIFPAIPGTEPTVVSCLTVHENLNFMAIGFTDGSVTLNKGDITRDRHSKTQ 180
RDGGNPLCTRIFPAIPGTEPTVVSCLTVHENLNFMAIGFTDGSVTLNKGDITRDRHSKTQ
Sbjct: 121 RDGGNPLCTRIFPAIPGTEPTVVSCLTVHENLNFMAIGFTDGSVTLNKGDITRDRHSKTQ 180
Query: 181 ILHKGNYPVTGLAFRQAGKTTHLFVVTTENVQSYIVSGKDYPRVELDTHGCGLRCSALSD 240
ILHKGNYPVTGLAFRQAGKTTHLFVVTTENVQSYIVSGKDYPRVELDTHGCGLRCSALSD
Sbjct: 181 ILHKGNYPVTGLAFRQAGKTTHLFVVTTENVQSYIVSGKDYPRVELDTHGCGLRCSALSD 240
Query: 241 PSQDLQFIVAGDECVYLYQPDERGPCFAFEGHKLIAHWFRGYLIIVSRDRKVSPKSEFTS 300
PSQDLQFIVAGDECVYLYQPDERGPCFAFEGHKLIAHWFRGYLIIVSRDRKVSPKSEFTS
Sbjct: 241 PSQDLQFIVAGDECVYLYQPDERGPCFAFEGHKLIAHWFRGYLIIVSRDRKVSPKSEFTS 300
Query: 301 RDSQSSDKQILNIYDLCNKFIAYSTVFEDVVDVLAEWGSLYVLTRDGRVHALQEKDTQTK 360
RDSQSSDKQILNIYDLCNKFIAYSTVFEDVVDVLAEWGSLYVLTRDGRVHALQEKDTQTK
Sbjct: 301 RDSQSSDKQILNIYDLCNKFIAYSTVFEDVVDVLAEWGSLYVLTRDGRVHALQEKDTQTK 360
Query: 361 LEMLFKKNLFEMAINLAKSQHLDSDGLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEP 420
LEMLFKKNLFEMAINLAKSQHLDSDGLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEP
Sbjct: 361 LEMLFKKNLFEMAINLAKSQHLDSDGLAQIFMQYGDHLYSKGNHDGAVQQYIRTIGKLEP 420
Query: 421 SYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSES 480
SYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSES
Sbjct: 421 SYVIRKFLDAQRIHNLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSES 480
Query: 481 EVHFDVETAIKVLRQAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQ 540
EVHFDVETAIKVLRQAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQ
Sbjct: 481 EVHFDVETAIKVLRQAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQ 540
Query: 541 AESNMKRYGKILMHHIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANN 600
AESNMKRYGKILMHHIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANN
Sbjct: 541 AESNMKRYGKILMHHIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANN 600
Query: 601 PRELKAFLEHMSEVQPDSPQGIYDTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFC 660
PRELKAFLEHMSEVQPDSPQGIYDTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFC
Sbjct: 601 PRELKAFLEHMSEVQPDSPQGIYDTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFC 660
Query: 661 DVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVISVCERHGEQDPSLW 720
DVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVISVCERHGEQDPSLW
Sbjct: 661 DVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQYRQVISVCERHGEQDPSLW 720
Query: 721 EQALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQTLAHNSTATLSVIRDYLVQKLQ 780
EQALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQTLAHNSTATLSVIRDYLVQKLQ
Sbjct: 721 EQALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQTLAHNSTATLSVIRDYLVQKLQ 780
Query: 781 KQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGH 840
KQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGH
Sbjct: 781 KQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGH 840
Query: 841 SFHQHCFESYSESDADCPTCLPENRKVMDMIRAQEQKRDLHDQFQHQLKCSNDSFSVIAD 900
SFHQHCFESYSESDADCPTCLPENRKVMDMIRAQEQKRDLHDQFQHQLKCSNDSFSVIAD
Sbjct: 841 SFHQHCFESYSESDADCPTCLPENRKVMDMIRAQEQKRDLHDQFQHQLKCSNDSFSVIAD 900
Query: 901 YFGRGVFNKLTLLTDPPTARLTSSLEAGLQRDLLMHSRRGT 941
YFGRGVFNKLTLLTDPPTARLTSSLEAGLQRDLLMHSRRGT
Sbjct: 901 YFGRGVFNKLTLLTDPPTARLTSSLEAGLQRDLLMHSRRGT 941
>gi|17978485 vacuolar protein sorting 18 [Homo sapiens]
Length = 973
Score = 62.4 bits (150), Expect = 2e-09
Identities = 90/428 (21%), Positives = 168/428 (39%), Gaps = 57/428 (13%)
Query: 436 LTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSKLEEFIKKKSESEVHFDVETAI-KVLR 494
LT +L L+ L L Y + K+ + F+ E F +I ++L
Sbjct: 491 LTTWLTELYLSRLGALQGDPEALTLYRETKECFRT--FLSSPRHKEWLFASRASIHELLA 548
Query: 495 QAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMH 554
G H +Y A +E + + + Y+EAL + + Q ++ IL+
Sbjct: 549 SHGDTEHMVYFAVIMQDYERVVAYHCQH-EAYEEALAVLARHRDPQL---FYKFSPILIR 604
Query: 555 HIPEQTTQLLKGLCTDYRPSLEGRSDREAPGCRANSEEFIPIFANNPR--------ELKA 606
HIP Q + G R ++ + IP N + +
Sbjct: 605 HIPRQLVDAWIEM-----------------GSRLDARQLIPALVNYSQGGEVQQVSQAIR 647
Query: 607 FLEHMSEVQPDSPQGIYDTLLELRLQNWAHEKDPQVKEKLHAEAISLLKSGRFCDVFDKA 666
++E V ++ Q I++ LL L +A + + L S R A
Sbjct: 648 YMEFCVNVLGETEQAIHNYLLSL----YARGRPDSLLAYLEQAGAS---PHRVHYDLKYA 700
Query: 667 LVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHEQ--YRQVISVCERHGEQDPSLWEQAL 724
L LC H +++Y+ +L+++ + +Q + +Q + E E LW +
Sbjct: 701 LRLCAEHGHHRACVHVYKVLELYEEAVDLALQVDVDLAKQCADLPEEDEELRKKLWLKIA 760
Query: 725 SYFARKEEDCKEYVAAVLKH--IENKNLMPPLLVVQTLAHNSTATLSVIRDYL--VQKLQ 780
+ ++EED + +A + ++ ++++P T+ H A S ++ Y +Q+LQ
Sbjct: 761 RHVVQEEEDVQTAMACLASCPLLKIEDVLPFFPDFVTIDHFKEAICSSLKAYNHHIQELQ 820
Query: 781 KQSQQIAQDELRVRRYREETTRIRQEIQELKAS-PKIFQKTKCSICN-SALELPSVHFLC 838
++ ++ R+RR ++QEL+ + + KC+ C+ L P FLC
Sbjct: 821 REMEEATASAQRIRR----------DLQELRGRYGTVEPQDKCATCDFPLLNRPFYLFLC 870
Query: 839 GHSFHQHC 846
GH FH C
Sbjct: 871 GHMFHADC 878
>gi|114199473 vacuolar protein sorting 41 isoform 2 [Homo sapiens]
Length = 829
Score = 47.8 bits (112), Expect = 5e-05
Identities = 72/298 (24%), Positives = 126/298 (42%), Gaps = 38/298 (12%)
Query: 589 NSEEFIPIFANNPRELKAFLEHMSEVQPDSPQGIYDTLLELRLQNWAHEKDPQVKEK--- 645
+SE+ + + +N E K ++ + E D P+ + L +L ++ H K + EK
Sbjct: 538 DSEKAVDMLLDN--EDKISIKKVVEELEDRPELQHVYLHKLFKRD--HHKGQRYHEKQIS 593
Query: 646 LHAE-----AISLLKSGRFCDVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHE 700
L+AE + L+ C + +KAL +CQ +F + +YL ++ M E
Sbjct: 594 LYAEYDRPNLLPFLRDSTHCPL-EKALEICQQRNFVEETVYLL--SRMGNSRSALKMIME 650
Query: 701 QYRQVISVCERHGEQDP-SLWEQALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQT 759
+ V E EQD LWE + Y D ++ +L +I + P+L++
Sbjct: 651 ELHDVDKAIEFAKEQDDGELWEDLILY----SIDKPPFITGLLNNIGTH--VDPILLIHR 704
Query: 760 LAHNSTATLSVIRDYLVQKLQKQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQK 819
+ + +RD LV+ LQ + QI E + ++ + +++ + + +
Sbjct: 705 IKEG--MEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDE 762
Query: 820 TKCSICNSALE--LPS--------VHFLCGHSFHQHCFESYSESDAD--CPTCLPENR 865
+IC S L LPS V F C H FH+ C S + A C C +NR
Sbjct: 763 E--NICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKNR 818
Score = 37.4 bits (85), Expect = 0.066
Identities = 25/110 (22%), Positives = 55/110 (50%), Gaps = 4/110 (3%)
Query: 335 AEWGSLYVLTRDGRVHALQEKDTQTKLEMLFKKNLFEMAINLAK--SQHLDSDGLAQIFM 392
+E SL+ + V +E+D ++ L +K +E A+ A+ +++ + I +
Sbjct: 315 SEGESLFYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGL 374
Query: 393 QYGDHLYSKGNHDGAVQQYIRTIGKLEP--SYVIRKFLDAQRIHNLTAYL 440
Y +HL +G++D A ++ + +GK Y + KF + ++ ++ YL
Sbjct: 375 AYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYL 424
>gi|114199475 vacuolar protein sorting 41 isoform 1 [Homo sapiens]
Length = 854
Score = 47.8 bits (112), Expect = 5e-05
Identities = 72/298 (24%), Positives = 126/298 (42%), Gaps = 38/298 (12%)
Query: 589 NSEEFIPIFANNPRELKAFLEHMSEVQPDSPQGIYDTLLELRLQNWAHEKDPQVKEK--- 645
+SE+ + + +N E K ++ + E D P+ + L +L ++ H K + EK
Sbjct: 563 DSEKAVDMLLDN--EDKISIKKVVEELEDRPELQHVYLHKLFKRD--HHKGQRYHEKQIS 618
Query: 646 LHAE-----AISLLKSGRFCDVFDKALVLCQMHDFQDGVLYLYEQGKLFQQIMHYHMQHE 700
L+AE + L+ C + +KAL +CQ +F + +YL ++ M E
Sbjct: 619 LYAEYDRPNLLPFLRDSTHCPL-EKALEICQQRNFVEETVYLL--SRMGNSRSALKMIME 675
Query: 701 QYRQVISVCERHGEQDP-SLWEQALSYFARKEEDCKEYVAAVLKHIENKNLMPPLLVVQT 759
+ V E EQD LWE + Y D ++ +L +I + P+L++
Sbjct: 676 ELHDVDKAIEFAKEQDDGELWEDLILY----SIDKPPFITGLLNNIGTH--VDPILLIHR 729
Query: 760 LAHNSTATLSVIRDYLVQKLQKQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQK 819
+ + +RD LV+ LQ + QI E + ++ + +++ + + +
Sbjct: 730 IKEG--MEIPNLRDSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDE 787
Query: 820 TKCSICNSALE--LPS--------VHFLCGHSFHQHCFESYSESDAD--CPTCLPENR 865
+IC S L LPS V F C H FH+ C S + A C C +NR
Sbjct: 788 E--NICESCLSPILPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKNR 843
Score = 37.4 bits (85), Expect = 0.066
Identities = 25/110 (22%), Positives = 55/110 (50%), Gaps = 4/110 (3%)
Query: 335 AEWGSLYVLTRDGRVHALQEKDTQTKLEMLFKKNLFEMAINLAK--SQHLDSDGLAQIFM 392
+E SL+ + V +E+D ++ L +K +E A+ A+ +++ + I +
Sbjct: 340 SEGESLFYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISQKNIKRHKILDIGL 399
Query: 393 QYGDHLYSKGNHDGAVQQYIRTIGKLEP--SYVIRKFLDAQRIHNLTAYL 440
Y +HL +G++D A ++ + +GK Y + KF + ++ ++ YL
Sbjct: 400 AYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYL 449
>gi|21071001 autocrine motility factor receptor [Homo sapiens]
Length = 643
Score = 42.0 bits (97), Expect = 0.003
Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 13/99 (13%)
Query: 792 RVRRYREETTRI-RQEIQELKASPK--IFQKTKCSIC----NSALELPSVHFLCGHSFHQ 844
R+RR++ + E + A+P+ C+IC +A +LP CGH FH
Sbjct: 308 RIRRHKNYLRVVGNMEARFAVATPEELAVNNDDCAICWDSMQAARKLP-----CGHLFHN 362
Query: 845 HCFESYSESDADCPTC-LPENRKVMDMIRAQEQKRDLHD 882
C S+ E D CPTC + N + +R + Q +L +
Sbjct: 363 SCLRSWLEQDTSCPTCRMSLNIADNNRVREEHQGENLDE 401
>gi|49640011 tetratricopeptide repeat domain 3 [Homo sapiens]
Length = 2025
Score = 40.0 bits (92), Expect = 0.010
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Query: 820 TKCSICNSALELPSVHFL-CGHSFHQHCFESYSESDADCPTC 860
+ C IC+ + +V L CGH +H+ CF+ + + + CP C
Sbjct: 1955 SSCEICHEVFKSKNVRVLKCGHKYHKGCFKQWLKGQSACPAC 1996
>gi|49640009 tetratricopeptide repeat domain 3 [Homo sapiens]
Length = 2025
Score = 40.0 bits (92), Expect = 0.010
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Query: 820 TKCSICNSALELPSVHFL-CGHSFHQHCFESYSESDADCPTC 860
+ C IC+ + +V L CGH +H+ CF+ + + + CP C
Sbjct: 1955 SSCEICHEVFKSKNVRVLKCGHKYHKGCFKQWLKGQSACPAC 1996
>gi|27436927 synoviolin 1 isoform b [Homo sapiens]
Length = 617
Score = 37.7 bits (86), Expect = 0.051
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 11/66 (16%)
Query: 808 QELKASPKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKV 867
+EL+A + C IC + + C H FH C S+ + CPTC
Sbjct: 282 EELQAMDNV-----CIICREEMVTGAKRLPCNHIFHTSCLRSWFQRQQTCPTCR------ 330
Query: 868 MDMIRA 873
MD++RA
Sbjct: 331 MDVLRA 336
>gi|27436925 synoviolin 1 isoform a [Homo sapiens]
Length = 616
Score = 37.7 bits (86), Expect = 0.051
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 11/66 (16%)
Query: 808 QELKASPKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKV 867
+EL+A + C IC + + C H FH C S+ + CPTC
Sbjct: 282 EELQAMDNV-----CIICREEMVTGAKRLPCNHIFHTSCLRSWFQRQQTCPTCR------ 330
Query: 868 MDMIRA 873
MD++RA
Sbjct: 331 MDVLRA 336
>gi|40805104 topoisomerase I binding, arginine/serine-rich [Homo
sapiens]
Length = 1045
Score = 37.7 bits (86), Expect = 0.051
Identities = 21/80 (26%), Positives = 39/80 (48%), Gaps = 5/80 (6%)
Query: 800 TTRIRQEIQELKASPKIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPT 859
T++++Q + ASP +KC IC + S C H F C + +S++ A+CP
Sbjct: 86 TSKLQQTVPA-DASPD----SKCPICLDRFDNVSYLDRCLHKFCFRCVQEWSKNKAECPL 140
Query: 860 CLPENRKVMDMIRAQEQKRD 879
C + +RA++ ++
Sbjct: 141 CKQPFDSIFHSVRAEDDFKE 160
>gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens]
Length = 485
Score = 37.4 bits (85), Expect = 0.066
Identities = 18/86 (20%), Positives = 40/86 (46%), Gaps = 9/86 (10%)
Query: 775 LVQKLQKQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSICNSALELPSV 834
++Q K+ +Q +++ +++ +EE ++ E + +C IC+ + +V
Sbjct: 364 IIQAKNKELEQTKEEKEKMQAQKEEVLSHMNDVLE--------NELQCIICSEYF-IEAV 414
Query: 835 HFLCGHSFHQHCFESYSESDADCPTC 860
C HSF +C + + +CP C
Sbjct: 415 TLNCAHSFCSYCINEWMKRKIECPIC 440
>gi|37655169 ring finger protein 135 isoform 2 [Homo sapiens]
Length = 210
Score = 37.0 bits (84), Expect = 0.087
Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 6/68 (8%)
Query: 822 CSICNSALELPSVHFLCGHSFHQHCFES-YSESDA---DCPTCLPENRKVMDMIRAQEQK 877
C IC L+ P+ CGHSF +HC E+ + DA CPTC + +R
Sbjct: 21 CIICQGLLDWPAT-LPCGHSFCRHCLEALWGARDARRWACPTC-RQGAAQQPHLRKNTLL 78
Query: 878 RDLHDQFQ 885
+DL D+++
Sbjct: 79 QDLADKYR 86
>gi|37655167 ring finger protein 135 isoform 1 [Homo sapiens]
Length = 432
Score = 37.0 bits (84), Expect = 0.087
Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 6/68 (8%)
Query: 822 CSICNSALELPSVHFLCGHSFHQHCFES-YSESDA---DCPTCLPENRKVMDMIRAQEQK 877
C IC L+ P+ CGHSF +HC E+ + DA CPTC + +R
Sbjct: 21 CIICQGLLDWPAT-LPCGHSFCRHCLEALWGARDARRWACPTC-RQGAAQQPHLRKNTLL 78
Query: 878 RDLHDQFQ 885
+DL D+++
Sbjct: 79 QDLADKYR 86
>gi|21389505 janus kinase and microtubule interacting protein 1
isoform 2 [Homo sapiens]
Length = 626
Score = 37.0 bits (84), Expect = 0.087
Identities = 32/111 (28%), Positives = 54/111 (48%), Gaps = 8/111 (7%)
Query: 766 ATLSVIRDYLVQKLQKQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSIC 825
ATL+V+RD K++ A++E R R + E R++QEI ELKA+ K ++ S C
Sbjct: 115 ATLNVLRDGAADKVKTALLTEAREEAR-RAFDGERLRLQQEILELKAARKQAEEA-LSNC 172
Query: 826 NSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVMDMIRAQEQ 876
A + + + HQ E C + R++MD I+ +++
Sbjct: 173 MQADKTKAADLRAAYQAHQ------DEVHRIKRECERDIRRLMDEIKGKDR 217
>gi|150456473 janus kinase and microtubule interacting protein 1
isoform 1 [Homo sapiens]
Length = 831
Score = 37.0 bits (84), Expect = 0.087
Identities = 32/111 (28%), Positives = 54/111 (48%), Gaps = 8/111 (7%)
Query: 766 ATLSVIRDYLVQKLQKQSQQIAQDELRVRRYREETTRIRQEIQELKASPKIFQKTKCSIC 825
ATL+V+RD K++ A++E R R + E R++QEI ELKA+ K ++ S C
Sbjct: 115 ATLNVLRDGAADKVKTALLTEAREEAR-RAFDGERLRLQQEILELKAARKQAEEA-LSNC 172
Query: 826 NSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVMDMIRAQEQ 876
A + + + HQ E C + R++MD I+ +++
Sbjct: 173 MQADKTKAADLRAAYQAHQ------DEVHRIKRECERDIRRLMDEIKGKDR 217
>gi|30348954 mindbomb homolog 1 [Homo sapiens]
Length = 1006
Score = 37.0 bits (84), Expect = 0.087
Identities = 22/79 (27%), Positives = 41/79 (51%), Gaps = 7/79 (8%)
Query: 783 SQQIAQDELRVRRYREETTRIRQEIQELKASPK-IFQKTKCSICNSALELPSVHFLCGHS 841
+ I+ + V + ++ T + ++Q+L+ + I ++T C +C L+ ++ FLCGH
Sbjct: 923 TDDISSGNIPVLQKDKDNTNVNADVQKLQQQLQDIKEQTMCPVCLDRLK--NMIFLCGHG 980
Query: 842 FHQHCFESYSESDADCPTC 860
Q C + SE CP C
Sbjct: 981 TCQLCGDRMSE----CPIC 995
>gi|239048909 checkpoint with forkhead and ring finger domains
isoform 5 [Homo sapiens]
Length = 572
Score = 36.2 bits (82), Expect = 0.15
Identities = 36/148 (24%), Positives = 58/148 (39%), Gaps = 12/148 (8%)
Query: 790 ELRVRRYREETTRIRQEIQELKASPKIFQKT-KCSICNSALELPSVHFLCGHSFHQHCFE 848
+L V + R + ++++ P ++T C IC L C H+F C+
Sbjct: 179 QLLVAQPRRNAQTVHEDVRAAAGKPDKMEETLTCIICQDLLHDCVSLQPCMHTFCAACYS 238
Query: 849 SYSESDADCPTCLPENRKVMDMIRAQEQKRDLHDQF--QHQLKCSNDSFSVIADYFGRGV 906
+ E + CPTC R ++ I +L + + QH K ++ D
Sbjct: 239 GWMERSSLCPTC----RCPVERICKNHILNNLVEAYLIQHPDKSRSEE-----DVQSMDA 289
Query: 907 FNKLTLLTDPPTARLTSSLEAGLQRDLL 934
NK+T P R + S E G DLL
Sbjct: 290 RNKITQDMLQPKVRRSFSDEEGSSEDLL 317
>gi|239048905 checkpoint with forkhead and ring finger domains
isoform 3 [Homo sapiens]
Length = 652
Score = 36.2 bits (82), Expect = 0.15
Identities = 36/148 (24%), Positives = 58/148 (39%), Gaps = 12/148 (8%)
Query: 790 ELRVRRYREETTRIRQEIQELKASPKIFQKT-KCSICNSALELPSVHFLCGHSFHQHCFE 848
+L V + R + ++++ P ++T C IC L C H+F C+
Sbjct: 259 QLLVAQPRRNAQTVHEDVRAAAGKPDKMEETLTCIICQDLLHDCVSLQPCMHTFCAACYS 318
Query: 849 SYSESDADCPTCLPENRKVMDMIRAQEQKRDLHDQF--QHQLKCSNDSFSVIADYFGRGV 906
+ E + CPTC R ++ I +L + + QH K ++ D
Sbjct: 319 GWMERSSLCPTC----RCPVERICKNHILNNLVEAYLIQHPDKSRSEE-----DVQSMDA 369
Query: 907 FNKLTLLTDPPTARLTSSLEAGLQRDLL 934
NK+T P R + S E G DLL
Sbjct: 370 RNKITQDMLQPKVRRSFSDEEGSSEDLL 397
>gi|239048862 checkpoint with forkhead and ring finger domains
isoform 2 [Homo sapiens]
Length = 663
Score = 36.2 bits (82), Expect = 0.15
Identities = 36/148 (24%), Positives = 58/148 (39%), Gaps = 12/148 (8%)
Query: 790 ELRVRRYREETTRIRQEIQELKASPKIFQKT-KCSICNSALELPSVHFLCGHSFHQHCFE 848
+L V + R + ++++ P ++T C IC L C H+F C+
Sbjct: 271 QLLVAQPRRNAQTVHEDVRAAAGKPDKMEETLTCIICQDLLHDCVSLQPCMHTFCAACYS 330
Query: 849 SYSESDADCPTCLPENRKVMDMIRAQEQKRDLHDQF--QHQLKCSNDSFSVIADYFGRGV 906
+ E + CPTC R ++ I +L + + QH K ++ D
Sbjct: 331 GWMERSSLCPTC----RCPVERICKNHILNNLVEAYLIQHPDKSRSEE-----DVQSMDA 381
Query: 907 FNKLTLLTDPPTARLTSSLEAGLQRDLL 934
NK+T P R + S E G DLL
Sbjct: 382 RNKITQDMLQPKVRRSFSDEEGSSEDLL 409
>gi|239048792 checkpoint with forkhead and ring finger domains
isoform 1 [Homo sapiens]
Length = 664
Score = 36.2 bits (82), Expect = 0.15
Identities = 36/148 (24%), Positives = 58/148 (39%), Gaps = 12/148 (8%)
Query: 790 ELRVRRYREETTRIRQEIQELKASPKIFQKT-KCSICNSALELPSVHFLCGHSFHQHCFE 848
+L V + R + ++++ P ++T C IC L C H+F C+
Sbjct: 271 QLLVAQPRRNAQTVHEDVRAAAGKPDKMEETLTCIICQDLLHDCVSLQPCMHTFCAACYS 330
Query: 849 SYSESDADCPTCLPENRKVMDMIRAQEQKRDLHDQF--QHQLKCSNDSFSVIADYFGRGV 906
+ E + CPTC R ++ I +L + + QH K ++ D
Sbjct: 331 GWMERSSLCPTC----RCPVERICKNHILNNLVEAYLIQHPDKSRSEE-----DVQSMDA 381
Query: 907 FNKLTLLTDPPTARLTSSLEAGLQRDLL 934
NK+T P R + S E G DLL
Sbjct: 382 RNKITQDMLQPKVRRSFSDEEGSSEDLL 409
>gi|239048907 checkpoint with forkhead and ring finger domains
isoform 4 [Homo sapiens]
Length = 623
Score = 36.2 bits (82), Expect = 0.15
Identities = 36/148 (24%), Positives = 58/148 (39%), Gaps = 12/148 (8%)
Query: 790 ELRVRRYREETTRIRQEIQELKASPKIFQKT-KCSICNSALELPSVHFLCGHSFHQHCFE 848
+L V + R + ++++ P ++T C IC L C H+F C+
Sbjct: 230 QLLVAQPRRNAQTVHEDVRAAAGKPDKMEETLTCIICQDLLHDCVSLQPCMHTFCAACYS 289
Query: 849 SYSESDADCPTCLPENRKVMDMIRAQEQKRDLHDQF--QHQLKCSNDSFSVIADYFGRGV 906
+ E + CPTC R ++ I +L + + QH K ++ D
Sbjct: 290 GWMERSSLCPTC----RCPVERICKNHILNNLVEAYLIQHPDKSRSEE-----DVQSMDA 340
Query: 907 FNKLTLLTDPPTARLTSSLEAGLQRDLL 934
NK+T P R + S E G DLL
Sbjct: 341 RNKITQDMLQPKVRRSFSDEEGSSEDLL 368
>gi|114155158 Ras association (RalGDS/AF-6) domain family
(N-terminal) member 9 [Homo sapiens]
Length = 435
Score = 36.2 bits (82), Expect = 0.15
Identities = 42/190 (22%), Positives = 83/190 (43%), Gaps = 25/190 (13%)
Query: 448 LANADHTTLLLNCYTKLKDSSKLEEFIKKKSESEVHFDVETAIKVLRQAGYYSHALYLAE 507
+ + DHT + ++K +L+ I+K E++ H D +V Y YL
Sbjct: 190 IISQDHTI-----HQQVKRMKELDLEIEK-CEAKFHLD-----RVENDGENYVQDAYLMP 238
Query: 508 NHAHHEWYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMHHIPEQTTQLLKGL 567
+ + E L +Q E+ + ++ G EQ E +K Y +IL+ + + + +K +
Sbjct: 239 SFSEVEQNLDLQYEENQTLEDLSESDG---IEQLEERLKYY-RILIDKLSAEIEKEVKSV 294
Query: 568 CTDYRPSLEGRSDREAPGCRANSEEFIPIFANNPRELKAFLE---HMSEVQPDSPQGIYD 624
C D EG + E S + + + +KA L+ H+S +Q + D
Sbjct: 295 CIDINEDAEGEAASELESSNLES-----VKCDLEKSMKAGLKIHSHLSGIQKEIKYS--D 347
Query: 625 TLLELRLQNW 634
+LL+++ + +
Sbjct: 348 SLLQMKAKEY 357
>gi|8051636 tRNA exportin [Homo sapiens]
Length = 962
Score = 36.2 bits (82), Expect = 0.15
Identities = 43/185 (23%), Positives = 73/185 (39%), Gaps = 35/185 (18%)
Query: 514 WYLKIQLEDIKNYQEALRYIGKLPFEQAESNMKRYGKILMHHIPEQTTQLLKGLCTDYRP 573
W I+ DIKN QEAL+ I E+ + ++L+H + ++ ++ G C DY
Sbjct: 306 WSKLIKNGDIKNAQEALQAI--------ETKVALMLQLLIHEDDDISSNII-GFCYDYLH 356
Query: 574 SLEGR---SDREAPGCRA------------------NSEEFIPIFANNPRELKAFLEHMS 612
L+ SD++ A N E +F ++LK L+ ++
Sbjct: 357 ILKQLTVLSDQQKANVEAIMLAVMKKLTYDEEYNFENEGEDEAMFVEYRKQLKLLLDRLA 416
Query: 613 EVQPDSPQGIYDTLLELRLQNWAHEKDPQVKEKLH-----AEAISLLKSGRFCDVFDKAL 667
+V P+ + LQNW + +V+ + AEA+ + F KA
Sbjct: 417 QVSPELLLASVRRVFSSTLQNWQTTRFMEVEVAIRLLYMLAEALPVSHGAHFSGDVSKAS 476
Query: 668 VLCQM 672
L M
Sbjct: 477 ALQDM 481
>gi|22027627 TNF receptor-associated factor 5 [Homo sapiens]
Length = 557
Score = 35.4 bits (80), Expect = 0.25
Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 6/65 (9%)
Query: 815 KIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVMDMIRAQ 874
++ ++ KC+ C+S L P CGH F QHC S E + P C P +++V I++Q
Sbjct: 38 RLEERYKCAFCHSVLHNPH-QTGCGHRFCQHCILSLRELNT-VPIC-PVDKEV---IKSQ 91
Query: 875 EQKRD 879
E +D
Sbjct: 92 EVFKD 96
>gi|77404348 TNF receptor-associated factor 5 [Homo sapiens]
Length = 557
Score = 35.4 bits (80), Expect = 0.25
Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 6/65 (9%)
Query: 815 KIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVMDMIRAQ 874
++ ++ KC+ C+S L P CGH F QHC S E + P C P +++V I++Q
Sbjct: 38 RLEERYKCAFCHSVLHNPH-QTGCGHRFCQHCILSLRELNT-VPIC-PVDKEV---IKSQ 91
Query: 875 EQKRD 879
E +D
Sbjct: 92 EVFKD 96
>gi|11321603 TNF receptor-associated factor 5 [Homo sapiens]
Length = 557
Score = 35.4 bits (80), Expect = 0.25
Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 6/65 (9%)
Query: 815 KIFQKTKCSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVMDMIRAQ 874
++ ++ KC+ C+S L P CGH F QHC S E + P C P +++V I++Q
Sbjct: 38 RLEERYKCAFCHSVLHNPH-QTGCGHRFCQHCILSLRELNT-VPIC-PVDKEV---IKSQ 91
Query: 875 EQKRD 879
E +D
Sbjct: 92 EVFKD 96
>gi|13569903 ring finger protein 32 [Homo sapiens]
Length = 362
Score = 35.0 bits (79), Expect = 0.33
Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 14/73 (19%)
Query: 822 CSICNSALEL-PSVHFLCGHSFHQHCFESYSE--SDADCPTCLPENRKVMDMIRAQEQKR 878
C IC EL P V C H FH+ C +++ + + CP C + Q Q R
Sbjct: 127 CPICKEEFELRPQVLLSCSHVFHKACLQAFEKFTNKKTCPLCR----------KNQYQTR 176
Query: 879 DLHDQFQ-HQLKC 890
+HD + ++KC
Sbjct: 177 VIHDGARLFRIKC 189
>gi|157266273 RANBP2-like and GRIP domain containing 1 [Homo
sapiens]
Length = 1756
Score = 34.3 bits (77), Expect = 0.56
Identities = 62/266 (23%), Positives = 107/266 (40%), Gaps = 61/266 (22%)
Query: 332 DVLAEWGSLYVLTRDGRVHALQEKDTQTKLEMLFKKNLFEMAINLAKSQHLDSDGLAQIF 391
D+L + +L +LT L +D Q E+L F+ A+ AKS +D L+ F
Sbjct: 233 DLLLAYANLMLLT-------LSTRDVQESRELL---ESFDSALQSAKSSLGGNDELSATF 282
Query: 392 MQYGDHLY--------SKGNHDGAVQ-QYIRTIGKLEPSYVIR--------KFLDAQRIH 434
++ H Y G H VQ Q + + L YVI K + +
Sbjct: 283 LEMKGHFYMHAGSLLLKMGQHGNNVQWQALSELAAL--CYVIAFQVPRPKIKLIKGEAGQ 340
Query: 435 NLTAYLQTLHRQSLANADHTTLLLNCYTKLKDSSK--LEEFIKKKSESEVHFDVETAIKV 492
NL L+ + L+ + H +LLN +D K +E F K +S ++
Sbjct: 341 NL---LEMMACDRLSQSGH--MLLNLSRGKQDFLKEVVETFANKSGQSVLY-------NA 388
Query: 493 LRQAGYYSHALYLAENHAHHEWYLKIQLEDIKNYQ-----------EALRYIG----KLP 537
L + +L + + + +LED+ Y + L ++G LP
Sbjct: 389 LFSSQSSKDTSFLGSDDIGNIDVQEPELEDLARYDVGAIQAHNGSLQHLTWLGLQWNSLP 448
Query: 538 FEQAESNMKRYGKILMHHIPEQTTQL 563
A ++++ K L HH+P++T++L
Sbjct: 449 ---ALPGIRKWLKQLFHHLPQETSRL 471
>gi|7662244 DAZ interacting protein 3, zinc finger [Homo sapiens]
Length = 1208
Score = 34.3 bits (77), Expect = 0.56
Identities = 14/44 (31%), Positives = 20/44 (45%), Gaps = 1/44 (2%)
Query: 818 QKTKCSICNSALELPSVHFL-CGHSFHQHCFESYSESDADCPTC 860
++ C IC+ L ++ L C H FH C + CPTC
Sbjct: 1144 EEEPCVICHENLSPENLSVLPCAHKFHAQCIRPWLMQQGTCPTC 1187
>gi|14149631 ring finger protein 112 [Homo sapiens]
Length = 632
Score = 34.3 bits (77), Expect = 0.56
Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 8/59 (13%)
Query: 822 CSICNSALELPSVHFLCGHSFHQHCFESYSESDADCPTCLPENRKVMDMIRAQEQKRDL 880
CSIC L P + CGH F CF ++ + P C PE RK+ +QKR L
Sbjct: 57 CSICLERLRDP-ISLDCGHDFCIRCFSTHRLPGCE-PPCCPECRKIC------KQKRGL 107
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,262,462
Number of Sequences: 37866
Number of extensions: 1645728
Number of successful extensions: 5149
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 82
Number of HSP's that attempted gapping in prelim test: 5079
Number of HSP's gapped (non-prelim): 145
length of query: 941
length of database: 18,247,518
effective HSP length: 112
effective length of query: 829
effective length of database: 14,006,526
effective search space: 11611410054
effective search space used: 11611410054
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.