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Search of human proteins with 17975763
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|17975763 myelin transcription factor 1 [Homo sapiens]
(1121 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|17975763 myelin transcription factor 1 [Homo sapiens] 2256 0.0
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 985 0.0
gi|7662168 suppression of tumorigenicity 18 [Homo sapiens] 836 0.0
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 90 1e-17
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 89 2e-17
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 89 3e-17
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] 82 3e-15
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 82 3e-15
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] 81 5e-15
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 79 2e-14
gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ... 78 4e-14
gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo ... 78 4e-14
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 78 4e-14
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 78 4e-14
gi|21735415 centromere protein B [Homo sapiens] 77 1e-13
gi|221219020 NYD-SP11 protein [Homo sapiens] 76 2e-13
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 76 2e-13
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 76 2e-13
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 76 2e-13
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 76 2e-13
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 76 2e-13
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 76 2e-13
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 76 2e-13
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 76 2e-13
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 76 2e-13
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 76 2e-13
gi|21361639 DIPB protein [Homo sapiens] 75 3e-13
gi|4503257 death-domain associated protein isoform a [Homo sapiens] 75 3e-13
gi|215422388 death-domain associated protein isoform a [Homo sap... 75 3e-13
gi|215422366 death-domain associated protein isoform b [Homo sap... 75 3e-13
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 2256 bits (5845), Expect = 0.0
Identities = 1121/1121 (100%), Positives = 1121/1121 (100%)
Query: 1 MSLENEDKRARTRSKALRGPPETTAADLSCPTPGCTGSGHVRGKYSRHRSLQSCPLAKKR 60
MSLENEDKRARTRSKALRGPPETTAADLSCPTPGCTGSGHVRGKYSRHRSLQSCPLAKKR
Sbjct: 1 MSLENEDKRARTRSKALRGPPETTAADLSCPTPGCTGSGHVRGKYSRHRSLQSCPLAKKR 60
Query: 61 KLEGAEAEHLVSKRKSHPLKLALDEGYGVDSDGSEDTEVKDASVSDESEGTLEGAEAETS 120
KLEGAEAEHLVSKRKSHPLKLALDEGYGVDSDGSEDTEVKDASVSDESEGTLEGAEAETS
Sbjct: 61 KLEGAEAEHLVSKRKSHPLKLALDEGYGVDSDGSEDTEVKDASVSDESEGTLEGAEAETS 120
Query: 121 GQDEIHRPETAEGRSPVKSHFGSNPIGSATASSKGSYSSYQGIIATSLLNLGQIAEETLV 180
GQDEIHRPETAEGRSPVKSHFGSNPIGSATASSKGSYSSYQGIIATSLLNLGQIAEETLV
Sbjct: 121 GQDEIHRPETAEGRSPVKSHFGSNPIGSATASSKGSYSSYQGIIATSLLNLGQIAEETLV 180
Query: 181 EEDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSL 240
EEDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSL
Sbjct: 181 EEDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSL 240
Query: 241 EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300
EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE
Sbjct: 241 EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300
Query: 301 EEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRK 360
EEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRK
Sbjct: 301 EEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRK 360
Query: 361 STVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEPGCPPAEQSQLGLGEPGKAAKPL 420
STVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEPGCPPAEQSQLGLGEPGKAAKPL
Sbjct: 361 STVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEPGCPPAEQSQLGLGEPGKAAKPL 420
Query: 421 DTVRKSYYSKDPSRAEKREIKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRIPPEILAMH 480
DTVRKSYYSKDPSRAEKREIKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRIPPEILAMH
Sbjct: 421 DTVRKSYYSKDPSRAEKREIKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRIPPEILAMH 480
Query: 481 ENVLKCPTPGCTGQGHVNSNRNTHRSLSGCPIAAAEKLAKSHEKQQPQTGDPSKSSSNSD 540
ENVLKCPTPGCTGQGHVNSNRNTHRSLSGCPIAAAEKLAKSHEKQQPQTGDPSKSSSNSD
Sbjct: 481 ENVLKCPTPGCTGQGHVNSNRNTHRSLSGCPIAAAEKLAKSHEKQQPQTGDPSKSSSNSD 540
Query: 541 RILRPMCFVKQLEVPPYGSYRPNVAPATPRANLAKELEKFSKVTFDYASFDAQVFGKRML 600
RILRPMCFVKQLEVPPYGSYRPNVAPATPRANLAKELEKFSKVTFDYASFDAQVFGKRML
Sbjct: 541 RILRPMCFVKQLEVPPYGSYRPNVAPATPRANLAKELEKFSKVTFDYASFDAQVFGKRML 600
Query: 601 APKIQTSETSPKAFQCFDYSQDAEAAHMAATAILNLSTRCWEMPENLSTKPQDLPSKSVD 660
APKIQTSETSPKAFQCFDYSQDAEAAHMAATAILNLSTRCWEMPENLSTKPQDLPSKSVD
Sbjct: 601 APKIQTSETSPKAFQCFDYSQDAEAAHMAATAILNLSTRCWEMPENLSTKPQDLPSKSVD 660
Query: 661 IEVDENGTLDLSMHKHRKRENAFPSSSSCSSSPGVKSPDASQRHSSTSAPSSSMTSPQSS 720
IEVDENGTLDLSMHKHRKRENAFPSSSSCSSSPGVKSPDASQRHSSTSAPSSSMTSPQSS
Sbjct: 661 IEVDENGTLDLSMHKHRKRENAFPSSSSCSSSPGVKSPDASQRHSSTSAPSSSMTSPQSS 720
Query: 721 QASRQDEWDRPLDYTKPSRLREEEPEESEPAAHSFASSEADDQEVSEENFEERKYPGEVT 780
QASRQDEWDRPLDYTKPSRLREEEPEESEPAAHSFASSEADDQEVSEENFEERKYPGEVT
Sbjct: 721 QASRQDEWDRPLDYTKPSRLREEEPEESEPAAHSFASSEADDQEVSEENFEERKYPGEVT 780
Query: 781 LTNFKLKFLSKDIKKELLTCPTPGCDGSGHITGNYASHRSLSGCPLADKSLRNLMAAHSA 840
LTNFKLKFLSKDIKKELLTCPTPGCDGSGHITGNYASHRSLSGCPLADKSLRNLMAAHSA
Sbjct: 781 LTNFKLKFLSKDIKKELLTCPTPGCDGSGHITGNYASHRSLSGCPLADKSLRNLMAAHSA 840
Query: 841 DLKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGVKVAPTKDDKEDPELMKCPVPGCVG 900
DLKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGVKVAPTKDDKEDPELMKCPVPGCVG
Sbjct: 841 DLKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGVKVAPTKDDKEDPELMKCPVPGCVG 900
Query: 901 LGHISGKYASHRSASGCPLAARRQKEGSLNGSSFSWKSLKNEGPTCPTPGCDGSGHANGS 960
LGHISGKYASHRSASGCPLAARRQKEGSLNGSSFSWKSLKNEGPTCPTPGCDGSGHANGS
Sbjct: 901 LGHISGKYASHRSASGCPLAARRQKEGSLNGSSFSWKSLKNEGPTCPTPGCDGSGHANGS 960
Query: 961 FLTHRSLSGCPRATFAGKKGKLSGDEVLSPKFKTSDVLENDEEIKQLNQEIRDLNESNSE 1020
FLTHRSLSGCPRATFAGKKGKLSGDEVLSPKFKTSDVLENDEEIKQLNQEIRDLNESNSE
Sbjct: 961 FLTHRSLSGCPRATFAGKKGKLSGDEVLSPKFKTSDVLENDEEIKQLNQEIRDLNESNSE 1020
Query: 1021 MEAAMVQLQSQISSMEKNLKNIEEENKLIEEQNEALFLELSGLSQALIQSLANIRLPHME 1080
MEAAMVQLQSQISSMEKNLKNIEEENKLIEEQNEALFLELSGLSQALIQSLANIRLPHME
Sbjct: 1021 MEAAMVQLQSQISSMEKNLKNIEEENKLIEEQNEALFLELSGLSQALIQSLANIRLPHME 1080
Query: 1081 PICEQNFDAYVSTLTDMYSNQDPENKDLLESIKQAVRGIQV 1121
PICEQNFDAYVSTLTDMYSNQDPENKDLLESIKQAVRGIQV
Sbjct: 1081 PICEQNFDAYVSTLTDMYSNQDPENKDLLESIKQAVRGIQV 1121
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 985 bits (2547), Expect = 0.0
Identities = 585/1244 (47%), Positives = 756/1244 (60%), Gaps = 183/1244 (14%)
Query: 1 MSLENEDKRARTRSKALRGPPETTAADL-SCPTPGCTGSGHVRGKYSRHRSLQSCPLAKK 59
M ++ E+KR RTRSK +R P E +L SCPTPGC GSGHV GKY+RHRS+ CPLAKK
Sbjct: 1 MEVDTEEKRHRTRSKGVRVPVEPAIQELFSCPTPGCDGSGHVSGKYARHRSVYGCPLAKK 60
Query: 60 RKLEGAEAEHLVSKRKSHPLKLAL--------------------DEG--YGVDSD--GSE 95
RK + + + KRK +K DEG Y D+D G E
Sbjct: 61 RKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDE 120
Query: 96 DTEVKDASVSDESEGTLEGAEAETSGQD---------EIHRPETAEGRSPVKSHFGSNPI 146
D E ++ +E E E + + G+D E E E + + + I
Sbjct: 121 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRI 180
Query: 147 GSATA---SSKGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKPGPGIVHLLQEAAE 203
T ++ Y +Y ++A SLLNLG+IAE+ ++ + L++ ++
Sbjct: 181 MQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRART--ESEMNSNTSNSLEDDSD 238
Query: 204 GAAS--EEGEKGLFIQPEDAEEVVEVT--------TERSQDLCPQSLEDAASEESSKQKG 253
+ + E L + + E V+ S+++ ++ D+ S++ S+
Sbjct: 239 KNENLGRKSELSLDLDSDVVRETVDSLKLLAQGHGVVLSENMNDRNYADSMSQQDSRNMN 298
Query: 254 ILSHEEEDEEEEEEEEEEEEDEE---------EEEEEEEEEEEEEEEEEEEEEEEEEEEE 304
+ + E+ EE DEE + + + E +E ++
Sbjct: 299 YVMLGKPMNNGLMEKMVEESDEEVCLSSLECLRNQCFDLARKLSETNPQERNPQQNMNIR 358
Query: 305 EEAAPDVIFQEDTSHTSAQKAPEL-RGPESPSPKPEYSVIVEVRSDD---DKDEDTHSRK 360
+ P+ F T + L R E SP+ V +D ++D+DT S
Sbjct: 359 QHVRPEEDFPGRTPDRNYSDMLNLMRLEEQLSPRSR--VFASCAKEDGCHERDDDTTSVN 416
Query: 361 STVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEPGCPPA----------EQSQLGL 410
S D SE MT+GNL LLE+AIAL+ E+ + + E A +QS L
Sbjct: 417 S---DRSEEVFDMTKGNLTLLEKAIALETERAKAMREKMAMEAGRRDNMRSYEDQSPRQL 473
Query: 411 GEPGKAAKPLDT---VRKSYYSKDPSRAEKREIKCPTPGCDGTGHVTGLYPHHRSLSGCP 467
PG+ KP + V+K YY DPSR EK+E KCPTPGCDGTGHVTGLYPHHRSLSGCP
Sbjct: 474 --PGEDRKPKSSDSHVKKPYY--DPSRTEKKESKCPTPGCDGTGHVTGLYPHHRSLSGCP 529
Query: 468 HKDRIPPEILAMHENVLKCPTPGCTGQGHVNSNRNTHRSLSGCPIAAAEKLAKSHEKQQP 527
HKDR+PPEILAMHE+VLKCPTPGCTG+GHVNSNRN+HRSLSGCPIAAAEKLAK+ EK Q
Sbjct: 530 HKDRVPPEILAMHESVLKCPTPGCTGRGHVNSNRNSHRSLSGCPIAAAEKLAKAQEKHQ- 588
Query: 528 QTGDPSKSSSNSDRILRPMCFVKQLEVPPYGSYRPNVAPATPRANLAKELEKFSKVTFDY 587
+ D SKSS SDR+LRPMCFVKQLE+P YG YR NV TPR+NLAKELEK+SK +F+Y
Sbjct: 589 -SCDVSKSSQASDRVLRPMCFVKQLEIPQYG-YRNNVPTTTPRSNLAKELEKYSKTSFEY 646
Query: 588 ASFDAQVFGKRMLAPKIQTSETSPKAFQ-------------------------------- 615
S+D +GKR +APK+QT + SPK +
Sbjct: 647 NSYDNHTYGKRAIAPKVQTRDISPKGYDDAKRYCKDPSPSSSSTSSYAPSSSSNLSCGGG 706
Query: 616 ----------CFDYSQDAEAAHMAATAILNLSTRCWEMPENLSTKPQDL-PSKSVDIEVD 664
FDY+ D EAAHMAATAILNLSTRC EMP+NLSTKPQDL +++ D+EVD
Sbjct: 707 SSASSTCSKSSFDYTHDMEAAHMAATAILNLSTRCREMPQNLSTKPQDLCATRNPDMEVD 766
Query: 665 ENGTLDLSMHKHRKRENAFPSSSSCSSSPGVKSPDASQRHSSTSAPSSSMTSPQSSQASR 724
ENGTLDLSM+K R R++ P + S ++ + + Q
Sbjct: 767 ENGTLDLSMNKQRPRDSCCPILTPLEPM---------------SPQQQAVMNNRCFQLGE 811
Query: 725 QDEWDRPLDYTK--PSRLREEEPEESEPAAHSFASSEADDQEVSEENFEERKYPGEVTLT 782
D WD P+DYTK P R+ E+E ++ P +D + +E EER+YPGEVT+
Sbjct: 812 GDCWDLPVDYTKMKPRRIDEDESKDITP----------EDLDPFQEALEERRYPGEVTIP 861
Query: 783 NFKLKFLS-KDIKKELLTCPTPGCDGSGHITGNYASHRSLSGCPLADKSLRNLMAAHSAD 841
+ K K+ K+ KK+L+T LSGCPLADKS+R+++A S +
Sbjct: 862 SPKPKYPQCKESKKDLIT---------------------LSGCPLADKSIRSMLATSSQE 900
Query: 842 LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGVKVAPTKDDKEDPELMKCPVPGCVGL 901
LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSG+++A +K+DKED E ++CPVPGC G
Sbjct: 901 LKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGIRIAQSKEDKEDQEPIRCPVPGCDGQ 960
Query: 902 GHISGKYASHRSASGCPLAARRQKEGSLNGSSFSWKSLKNEGPTCPTPGCDGSGHANGSF 961
GHI+GKYASHRSASGCPLAA+RQK+G LNGS FSWKS+K EG +CPTPGCDGSGH +GSF
Sbjct: 961 GHITGKYASHRSASGCPLAAKRQKDGYLNGSQFSWKSVKTEGMSCPTPGCDGSGHVSGSF 1020
Query: 962 LTHRSLSGCPRATFAGKKGKLSGDEVLSPKFKTSDVLENDEEIKQLNQEIRDLNESNSEM 1021
LTHRSLSGCPRAT A KK KLSG+++L+ K + S+ +ENDEEIKQL++EI++LNESNS+M
Sbjct: 1021 LTHRSLSGCPRATSAMKKAKLSGEQMLTIKQRASNGIENDEEIKQLDEEIKELNESNSQM 1080
Query: 1022 EAAMVQLQSQISSMEKNLKNIEEENKLIEEQNEALFLELSGLSQALIQSLANIRLPHMEP 1081
EA M++L++QI++ME NLK IEEENK+IE+QNE+L EL+ LSQ+LI SLANI+LPHM+P
Sbjct: 1081 EADMIKLRTQITTMESNLKTIEEENKVIEQQNESLLHELANLSQSLIHSLANIQLPHMDP 1140
Query: 1082 ICEQNFDAYVSTLTDMYSNQD----PENKDLLESIKQAVRGIQV 1121
I EQNFDAYV+TLT+MY+NQD PENK LLE+IKQAVRGIQV
Sbjct: 1141 INEQNFDAYVTTLTEMYTNQDRYQSPENKALLENIKQAVRGIQV 1184
>gi|7662168 suppression of tumorigenicity 18 [Homo sapiens]
Length = 1047
Score = 836 bits (2159), Expect = 0.0
Identities = 528/1163 (45%), Positives = 682/1163 (58%), Gaps = 158/1163 (13%)
Query: 1 MSLENEDKRARTRSKALRGPPETTAADLSCPTPGCTGSGHVRGKYSRHRSLQSCPLAKKR 60
M E EDK RTRSK P ++ +LS C +AKKR
Sbjct: 1 MDAEAEDKTLRTRSKGTEVPMDSLIQELSVA--------------------YDCSMAKKR 40
Query: 61 KLEGAEAEHLVSKRKSHPLKLALDEGYGVDSDGSEDTEVKDASVSDESEGTLEGAEAETS 120
E V+KRKS +K Y +D ED S E +G LE ++
Sbjct: 41 TAEDQALGVPVNKRKSLLMK---PRHYSPKADCQEDR-----SDRTEDDGPLE-THGHST 91
Query: 121 GQDEIHRPETAEGRSPVKSHFGSNPIGSATASSKGSYSSYQGIIATSLLNLGQIAEETLV 180
++ + +P S + + ++ + YS YQ ++ SL++LG+ + V
Sbjct: 92 AEEIMIKPMDESLLSTAQEN---------SSRKEDRYSCYQELMVKSLMHLGKFEKNVSV 142
Query: 181 E---EDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCP 237
+ E+L + GI L E S+E ++ I +D + ++ + C
Sbjct: 143 QTVSENLNDS-----GIQSLKAE------SDEADECFLIHSDDGRDKID---DSQPPFC- 187
Query: 238 QSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 297
S +D S S + G S EE + + + +++ E E + E ++
Sbjct: 188 -SSDDNESNSESAENGWDSGSNFSEETKPPRVPKYVLTDHKKDLLEVPEIKTEGDKFIPC 246
Query: 298 EEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTH 357
E + E E ++D + A+ P P D ++ED+
Sbjct: 247 ENRCDSETE-------RKDPQNALAEPLDGNAQPSFP---------------DVEEEDSE 284
Query: 358 SRKSTVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEPGCPPAEQSQLG-LGEPGKA 416
S + S+++ +GNL LLEQAIAL+AE+ V ++ L L +
Sbjct: 285 SLAVMTEEGSDLEK--AKGNLSLLEQAIALQAER-GCVFHNTYKELDRFLLEHLAGERRQ 341
Query: 417 AKPLDTV-RKSYYSKDPSRAEKREIKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRIPPE 475
K +D R+ + +K R EKRE KCP PGCDGTGHVTGLYPHHRSLSGCPHK R+P E
Sbjct: 342 TKVIDMGGRQIFNNKHSPRPEKRETKCPIPGCDGTGHVTGLYPHHRSLSGCPHKVRVPLE 401
Query: 476 ILAMHENVLKCPTPGCTGQGHVNSNRNTHRSLSGCPIAAAEKLAKSHEKQQ---PQTGD- 531
ILAMHENVLKCPTPGCTG+GHVNSNRNTHRSLSGCPIAAAEKLA S +K Q PQTG
Sbjct: 402 ILAMHENVLKCPTPGCTGRGHVNSNRNTHRSLSGCPIAAAEKLAMSQDKNQLDSPQTGQC 461
Query: 532 PSKSSSNSDRILRPMCFVKQLEVPPYGSYRPNVAPATPRANLAKELEKFSKVTFDYASFD 591
P ++ S VKQ+E P+ A +PRA ++KE EKF KV FDYASFD
Sbjct: 462 PDQAHRTS--------LVKQIEFN-----FPSQAITSPRATVSKEQEKFGKVPFDYASFD 508
Query: 592 AQVFGKRMLAPKIQTSET---------------------------SPKAFQCFDYSQDAE 624
AQVFGKR L +Q +T SP + Y Q +E
Sbjct: 509 AQVFGKRPLIQTVQGRKTPPFPESKHFPNPVKFPNRLPSAGAHTQSPGRASSYSYGQCSE 568
Query: 625 AAHMAATA-ILNLSTRCWEMPENLSTKPQDLPSKSVDIEVDENGTLDLSMHKHRKRENAF 683
H+AA A ILNLSTRC E + LS KPQ L +K +IEVDENGTLDLSM K+R + +
Sbjct: 569 DTHIAAAAAILNLSTRCREATDILSNKPQSLHAKGAEIEVDENGTLDLSMKKNRILDKSA 628
Query: 684 PSSSSCSSSPGVKSPDASQRHSSTSAPSSSMTSPQSSQA-SRQDEWDRPLDYTKPSRLRE 742
P +SS +S P +P SS SS + + QA Q+ WD P++Y+K E
Sbjct: 629 PLTSSNTSIP---TPS-----SSPFKTSSILVNAAFYQALCDQEGWDTPINYSKTHGKTE 680
Query: 743 EEPEESEPAAHSFASSEADDQEVSEENFEERKYPGEVTLTNFKLKFLSKDIKKELLTCPT 802
EE E+ D S EN EE+K+PGE ++ + K K ++D+KKEL+TCPT
Sbjct: 681 EEKEK--------------DPVSSLENLEEKKFPGEASIPSPKPKLHARDLKKELITCPT 726
Query: 803 PGCDGSGHITGNYASHRSLSGCPLADKSLRNLMAAHSADLKCPTPGCDGSGHITGNYASH 862
PGCDGSGH+TGNYASHRS+SGCPLADK+L++LMAA+S +LKCPTPGCDGSGH+TGNYASH
Sbjct: 727 PGCDGSGHVTGNYASHRSVSGCPLADKTLKSLMAANSQELKCPTPGCDGSGHVTGNYASH 786
Query: 863 RSLSGCPRAKKSGVKVAPTKDDKEDPELMKCPVPGCVGLGHISGKYASHRSASGCPLAAR 922
RSLSGCPRA+K GVK+ PTK++KEDPEL KCPV GC G GHISGKY SHR+ASGCPLAA+
Sbjct: 787 RSLSGCPRARKGGVKMTPTKEEKEDPEL-KCPVIGCDGQGHISGKYTSHRTASGCPLAAK 845
Query: 923 RQKEGSLNGSSFSWKSLKNEGPTCPTPGCDGSGHANGSFLTHRSLSGCPRATFAGKKGKL 982
RQKE LNG+S SWK K E P CP PGC+G GH N F+THRSLSGCP KKGK+
Sbjct: 846 RQKENPLNGASLSWKLNKQELPHCPLPGCNGLGHVNNVFVTHRSLSGCPLNAQVIKKGKV 905
Query: 983 SGDEVLSPKFKTSDVLENDEEIKQLNQEIRDLNESNSEMEAAMVQLQSQISSMEKNLKNI 1042
S +E+++ K K + +E+DEEI+ L++EI++LNESN ++EA M++LQ+QI+SME NLK I
Sbjct: 906 S-EELMTIKLKATGGIESDEEIRHLDEEIKELNESNLKIEADMMKLQTQITSMESNLKTI 964
Query: 1043 EEENKLIEEQNEALFLELSGLSQALIQSLANIRLPHMEPICEQNFDAYVSTLTDMYSNQD 1102
EEENKLIE+ NE+L EL+GLSQALI SLA+I+LP M PI EQNF+AYV+TLTDMYSN +
Sbjct: 965 EEENKLIEQNNESLLKELAGLSQALISSLADIQLPQMGPISEQNFEAYVNTLTDMYSNLE 1024
Query: 1103 ----PENKDLLESIKQAVRGIQV 1121
PE K LLESIKQAV+GI V
Sbjct: 1025 RDYSPECKALLESIKQAVKGIHV 1047
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 89.7 bits (221), Expect = 1e-17
Identities = 63/158 (39%), Positives = 80/158 (50%), Gaps = 34/158 (21%)
Query: 244 ASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEE------------- 290
A EE I S +EE+EEEEEEEEEEEE+EEEEE+ EEEEE+EEE
Sbjct: 873 ALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFE 932
Query: 291 ----------EEEEEEEEEEEEEEEEAAPDVIF------QEDTSHTSAQKAPELRGPES- 333
EEEEEEE+EEEEEE E D+ F E+ + P L PES
Sbjct: 933 EEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESP 992
Query: 334 ----PSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDES 367
P P+PE +++EV ++E T+ E+
Sbjct: 993 PKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEA 1030
Score = 39.7 bits (91), Expect = 0.016
Identities = 56/252 (22%), Positives = 86/252 (34%), Gaps = 13/252 (5%)
Query: 91 SDGSEDTEVKDASVSDESEGTLEGAEAETSGQDEIHRPETAEGRSPVKSHFGSNPIGSAT 150
SD E+ E ++ +E E E E E ++E E E + F
Sbjct: 886 SDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEE-EEEFEEEFEEEEGELEE 944
Query: 151 ASSKGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKPGPGIVHLL---QEAAEGAAS 207
+ + + L G E VEE A P P + L + +
Sbjct: 945 EEEEEDEEEEEELEEVEDLEFGTAGGE--VEE----GAPPPPTLPPALPPPESPPKVQPE 998
Query: 208 EEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEE 267
E E GL ++ E+ E + + L P++L E + ++ EEE
Sbjct: 999 PEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEP 1058
Query: 268 EEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPE 327
EEE E+ ++ + E EEE E E E E + Q+DT+ A
Sbjct: 1059 SAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKE---QDDTAAMLADFIDC 1115
Query: 328 LRGPESPSPKPE 339
E P P E
Sbjct: 1116 PPDDEKPPPPTE 1127
Score = 36.6 bits (83), Expect = 0.14
Identities = 51/221 (23%), Positives = 69/221 (31%), Gaps = 80/221 (36%)
Query: 199 QEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHE 258
+E E EE E+ + ED EE E E ++ EE +++G L E
Sbjct: 895 EEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEF---------EEEFEEEEGELEEE 945
Query: 259 EEDEEEEEEE-------------------------------------------------- 268
EE+E+EEEEE
Sbjct: 946 EEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGL 1005
Query: 269 --EEEEEDEEEEE---------------EEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDV 311
E EE EEE + E E E E +E EEE +AP
Sbjct: 1006 LLEVEEPGTEEERGADTAPTLAPEALPSQGEVE--REGESPAAGPPPQELVEEEPSAPPT 1063
Query: 312 IFQEDTSHTS--AQKAPELRGPESPSPKPEYSVIVEVRSDD 350
+ +E+T S Q PE E + E + E DD
Sbjct: 1064 LLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDD 1104
Score = 33.5 bits (75), Expect = 1.2
Identities = 37/161 (22%), Positives = 64/161 (39%), Gaps = 10/161 (6%)
Query: 296 EEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDED 355
+EEEEEEEEEE + +E+ ++ E E + E+ E + ++E+
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946
Query: 356 THSRKSTVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEPGCPPAEQSQ-------- 407
+ + E++D+ G +E+ + P PP Q +
Sbjct: 947 EEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLL 1006
Query: 408 LGLGEPG-KAAKPLDTVRKSYYSKDPSRAE-KREIKCPTPG 446
L + EPG + + DT PS+ E +RE + P G
Sbjct: 1007 LEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAG 1047
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 89.0 bits (219), Expect = 2e-17
Identities = 86/287 (29%), Positives = 121/287 (42%), Gaps = 19/287 (6%)
Query: 88 GVDSDGSEDTEVKDASVSDESEGTLEGAEAETSGQDEIHR--PETAEGRSPVKSHFGSNP 145
G + +G E E K +E EG EG E E G++E E EG+ + G
Sbjct: 811 GGEVEGGEVEEGKGEREEEEEEG--EGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGE 868
Query: 146 IGSATASSKGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKPGPGIVHLLQEAAEGA 205
+G +G G+ E EE+ G+ G +E EG
Sbjct: 869 EEGEEGEGEGEEEEGEGE--------GEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGK 920
Query: 206 ASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEE 265
EEGE+G + E EE E E + + E+ E +++G EEE E E
Sbjct: 921 GEEEGEEG---EGEGEEEEGEGEGEDGEG---EGEEEEGEWEGEEEEGEGEGEEEGEGEG 974
Query: 266 EEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKA 325
EE E E E+EE E E EEEE EEE EEE E EEE E E EE + E +
Sbjct: 975 EEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEG 1034
Query: 326 PELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSR-KSTVTDESEMQD 371
E G E + + E R + +++E+ + + T +E+E QD
Sbjct: 1035 EEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQD 1081
Score = 75.9 bits (185), Expect = 2e-13
Identities = 77/253 (30%), Positives = 103/253 (40%), Gaps = 18/253 (7%)
Query: 84 DEGYGVDSDGS---EDTEVKDASVSDESEGTLEGAEAETSGQDEIHRPE-TAEGRSPVKS 139
+EG G + +G E+ E K +E EG EG E E G++E E EG +
Sbjct: 838 EEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEE 897
Query: 140 HFGSNPIGSATASSKGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKPGPGIVHLLQ 199
G G +G +G G+ E EE+ + G G +
Sbjct: 898 EEGEGE-GEEEGEGEGEEEEGEGKGEEE----GEEGEGEGEEEEGEGEGEDGEGEGEEEE 952
Query: 200 -------EAAEGAASEEGE-KGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQ 251
E EG EEGE +G + E EE E E + + E+ EE +
Sbjct: 953 GEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGE-EEGEEEGEGEEEGEG 1011
Query: 252 KGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDV 311
+G E E E E E EE E E EEEE EEE EE E+E E EE EEEEEEE
Sbjct: 1012 EGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQE 1071
Query: 312 IFQEDTSHTSAQK 324
+E+ ++
Sbjct: 1072 TGEEENERQDGEE 1084
Score = 68.6 bits (166), Expect = 3e-11
Identities = 79/343 (23%), Positives = 132/343 (38%), Gaps = 43/343 (12%)
Query: 40 HVRGKYSRHRSLQSCPLAKKRKLEGAEAEHLVSKRKSHPLKLALDEGYGVDSDGSED-TE 98
H+ S +SL+ P+ K++K + + + D DSD E+ +E
Sbjct: 504 HIMSLNSNEKSLKLSPVQKQKK------QQTIGELTQDTALTEND-----DSDEYEEMSE 552
Query: 99 VKDASVSDE--SEG---TLEGAEAETSGQDEIHRPETAEGRSPVKSHFGSNPIGSATASS 153
+K+ + S+G T E +E+ PE EG K N I +
Sbjct: 553 MKEGKACKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAEDSKG----NGIEEQEVEA 608
Query: 154 KGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKPGPGIVHLLQEAAEG------AAS 207
G G+ + ++ +DL A+ G + EA +G
Sbjct: 609 NEENVKVHG---------GRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTC 659
Query: 208 EEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEE 267
EEG G ++ E E R + P E +E+ +K +E+ E E+
Sbjct: 660 EEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGH 719
Query: 268 EEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPE 327
++E ++ EE EEE E EEEE + EEEEE+E E +EE + + E +K E
Sbjct: 720 QKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEE 779
Query: 328 LRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQ 370
G E + E + ++E+T R + E++
Sbjct: 780 RAGKEEKGEE-------EGDQGEGEEEETEGRGEEKEEGGEVE 815
Score = 66.6 bits (161), Expect = 1e-10
Identities = 49/127 (38%), Positives = 64/127 (50%), Gaps = 1/127 (0%)
Query: 181 EEDLGQAAKPGPGI-VHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQS 239
EE G+ + G G V +E EG +E G + E+ + E E ++ +
Sbjct: 749 EEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEK 808
Query: 240 LEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEE 299
E E ++G EEE+EE E EEEE E +EEE E EEEE E + EEE EE E E
Sbjct: 809 EEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGE 868
Query: 300 EEEEEEE 306
EE EE E
Sbjct: 869 EEGEEGE 875
Score = 66.6 bits (161), Expect = 1e-10
Identities = 83/314 (26%), Positives = 112/314 (35%), Gaps = 32/314 (10%)
Query: 84 DEGYGVDSDGSEDTEVKDASVSDESEGTLEGAEAETSGQDEIHRPETAEGRSPVKSHFGS 143
+EG G + +G + E + + + +G E G+ E E EGR K G
Sbjct: 757 EEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGE---EEETEGRGEEKEE-GG 812
Query: 144 NPIGSATASSKGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKPGPGIVHLLQEAAE 203
G KG + G+ EE E+ + G +E E
Sbjct: 813 EVEGGEVEEGKGEREEEE--------EEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEE 864
Query: 204 GAASEEGEKGLFIQPEDAEEVV-------EVTTERSQDLCPQSLEDAASEESSKQKGILS 256
G EEGE+G E+ E E E + + E EE + KG
Sbjct: 865 GEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEE 924
Query: 257 HEEEDEEEEEEE-------------EEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303
EE + E EEEE EEE E E EEEE E E EEE E E EE E E EEE
Sbjct: 925 GEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEE 984
Query: 304 EEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTV 363
E E + E+ + E G + E VE + + E+ +
Sbjct: 985 EGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGE 1044
Query: 364 TDESEMQDMMTRGN 377
E E + R N
Sbjct: 1045 EREKEGEGEENRRN 1058
Score = 60.5 bits (145), Expect = 9e-09
Identities = 50/152 (32%), Positives = 71/152 (46%), Gaps = 2/152 (1%)
Query: 181 EEDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSL 240
+++ Q + G H E EG EE EK + ++ E EV ER ++ +
Sbjct: 720 QKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEG--EGKEEGEGEEVEGEREKEEGERKK 777
Query: 241 EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300
E+ A +E ++ E E+EE E EE+EE E E E EE + E EEEEEE E EE
Sbjct: 778 EERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEE 837
Query: 301 EEEEEEAAPDVIFQEDTSHTSAQKAPELRGPE 332
EE E E +E+ ++ E G E
Sbjct: 838 EEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEE 869
Score = 58.5 bits (140), Expect = 3e-08
Identities = 73/223 (32%), Positives = 90/223 (40%), Gaps = 46/223 (20%)
Query: 83 LDEGYGVDSDGSEDTEVKDASVSDESEGTLEGAEAETSGQDEIHRPETAEGRSPVKSHFG 142
++EG G + G + E D +E EG EG E E G++ E EG + G
Sbjct: 727 MEEG-GEEEHGEGEEEEGDREEEEEKEG--EGKE-EGEGEEVEGEREKEEGERKKEERAG 782
Query: 143 SNPIGSATASSKGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKPGPGIVHLLQEAA 202
KG QG G+ EET E G+ + G + E
Sbjct: 783 KE--------EKGEEEGDQGE--------GE-EEET---EGRGEEKEEGGEVEGGEVEEG 822
Query: 203 EGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDE 262
+G EE E+G E EE E E E EE + KG +E
Sbjct: 823 KGEREEEEEEG-----EGEEEEGEGEEE----------EGEGEEEEGEGKG-------EE 860
Query: 263 EEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305
E EE E EEE +E E E EEEE E E EEE E E EEEE E E
Sbjct: 861 EGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGE 903
Score = 57.4 bits (137), Expect = 8e-08
Identities = 67/294 (22%), Positives = 120/294 (40%), Gaps = 31/294 (10%)
Query: 90 DSDGSEDT-----EVKDASVSDESEGTLEGAEAETS--GQDEIHRPETAEGRSPVKSHFG 142
+ +G+ED+ E ++ ++E+ G + +T D + E +EG++
Sbjct: 589 EKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKAKSVGEAE 648
Query: 143 SNPIGSATASSKGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKPGPGIVHLLQEAA 202
P G + + S + Q E E+D G+ PG +
Sbjct: 649 DGPEGRGDGTCEEGSSGAEH---------WQDEEREKGEKDKGRGEMERPG-----EGEK 694
Query: 203 EGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDE 262
E A EE +K + E E ER+Q++ E+ E +++G + E+E
Sbjct: 695 ELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHG--EGEEEEG----DREEE 748
Query: 263 EEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSA 322
EE+E E +EE + EE E E E+EE E ++EE +EE+ EEE + + +
Sbjct: 749 EEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEK 808
Query: 323 QKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRG 376
++ E+ G E K E E ++ + E+ E E ++ +G
Sbjct: 809 EEGGEVEGGEVEEGKGER----EEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKG 858
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 88.6 bits (218), Expect = 3e-17
Identities = 71/205 (34%), Positives = 93/205 (45%), Gaps = 15/205 (7%)
Query: 107 ESEGTLEGAEAETSGQDEIHRPETAEGRSP-----------VKSHFGSNPIGS---ATAS 152
E E +GA A+ + E E + P +K NP G A A
Sbjct: 692 EEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAEAE 751
Query: 153 SKGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKPGPGIVHLLQEAAEGAASEEGEK 212
S G +G A + ET E + G+ G G + AEG EGE
Sbjct: 752 STGEMPGEEGETAGEGETEEKSGGETQPEGE-GETETQGKGEECEDENEAEGKGDNEGED 810
Query: 213 GLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEE 272
I ED E SQ+L ++ +A ++E + G S + EEEEEEEEE+E
Sbjct: 811 EGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQE 870
Query: 273 EDEEEEEEEEEEEEEEEEEEEEEEE 297
E+EEEEE+EEEEEEEEEEEE+ EE
Sbjct: 871 EEEEEEEQEEEEEEEEEEEEKGNEE 895
Score = 45.8 bits (107), Expect = 2e-04
Identities = 62/250 (24%), Positives = 86/250 (34%), Gaps = 86/250 (34%)
Query: 181 EEDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSL 240
EE L Q A+ P Q AE EE L V ++ ++ ++ P
Sbjct: 693 EESLNQGARAQP------QAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKEN--PGGQ 744
Query: 241 EDAASEESS------------------KQKGILSHEEEDEEEEEEEEEEEEDEEEEE--- 279
ED A ES+ K G E E E E + + EE EDE E E
Sbjct: 745 EDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKG 804
Query: 280 ----EEE-----------------------------------------------EEEEEE 288
E+E EEEEE
Sbjct: 805 DNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEE 864
Query: 289 EEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPES------PSPKPEYSV 342
EEEE+EEEEEEEE+EEEE + ++ + PE R ++ P P +
Sbjct: 865 EEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQAIYLFLLPIVFPLWLT 924
Query: 343 IVEVRSDDDK 352
+ +VR + +
Sbjct: 925 VPDVRRQESR 934
>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
Length = 185
Score = 82.0 bits (201), Expect = 3e-15
Identities = 40/62 (64%), Positives = 53/62 (85%)
Query: 245 SEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 304
+EE S Q+G+ EEE EEEEEE EEEE++EE+EE+EEEEE+EEE+EE+EEEEE+E ++
Sbjct: 107 AEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKM 166
Query: 305 EE 306
EE
Sbjct: 167 EE 168
Score = 63.9 bits (154), Expect = 8e-10
Identities = 34/64 (53%), Positives = 45/64 (70%)
Query: 243 AASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEE 302
A + S + L EE ++ EEEE +EEEEE EEEE+EEE+EE+EEEEE+EEE+
Sbjct: 93 AGNRLSVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEK 152
Query: 303 EEEE 306
EE+E
Sbjct: 153 EEDE 156
Score = 62.8 bits (151), Expect = 2e-09
Identities = 30/65 (46%), Positives = 47/65 (72%)
Query: 238 QSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 297
Q L E +++ + E+E+E+EE+EEEEE+E+E+EE+EEEEE+E ++ EEE+ EE
Sbjct: 114 QGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEE 173
Query: 298 EEEEE 302
E + E
Sbjct: 174 EIDTE 178
Score = 60.5 bits (145), Expect = 9e-09
Identities = 39/97 (40%), Positives = 55/97 (56%), Gaps = 21/97 (21%)
Query: 201 AAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEE 260
AA A ++GL ++ E+ EE E+ EE K++ +EE
Sbjct: 103 AALVAEECSAQQGLPVEEEEVEE-----------------EEEEVEEEEKEE----EKEE 141
Query: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 297
DEEEEE+EEE+EEDEEEEE+E ++ EEE+ EEE + E
Sbjct: 142 DEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
Score = 58.5 bits (140), Expect = 3e-08
Identities = 29/67 (43%), Positives = 45/67 (67%)
Query: 232 SQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEE 291
+Q P E+ EE ++ E+E++EEEEE+EEE+E++EEEEE+E ++ EEE+
Sbjct: 112 AQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKV 171
Query: 292 EEEEEEE 298
EEE + E
Sbjct: 172 EEEIDTE 178
Score = 42.7 bits (99), Expect = 0.002
Identities = 37/155 (23%), Positives = 70/155 (45%), Gaps = 21/155 (13%)
Query: 210 GEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEE 269
G +G ++P A ++ +T++R+++L P + + EE Q+ + +D + +
Sbjct: 30 GREGWRVKP--AHTLLAMTSQRNKELRPSTCLEV--EEKWLQRWAVGLPVKDSGVSQAKI 85
Query: 270 EEEED-----------------EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVI 312
+ D EE ++ EEEE EEEEEE EEEE+EEE+ +
Sbjct: 86 WGKNDLSAGNRLSVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEE 145
Query: 313 FQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVR 347
+++ ++ E G + K E + E++
Sbjct: 146 EEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQ 180
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 82.0 bits (201), Expect = 3e-15
Identities = 72/202 (35%), Positives = 94/202 (46%), Gaps = 35/202 (17%)
Query: 265 EEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQK 324
+EEEEEEEEDEEEEEE+EEEEEEEEEEEEEEEEEEEEEEE AA V E S
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAA--VALGEVLGPRSGSS 789
Query: 325 APELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQD------MMTRGNL 378
+ G E + + + + +DD K ++ R S + E ++ +++ G++
Sbjct: 790 S---EGSERSTDRSQEGAPSTLLADDQK--ESRGRASMADGDLEPEEGSKTLVLVSPGDM 844
Query: 379 GLLEQAIALKAEQVRTVCEPGCPPAEQ-----SQLGLGEPGKAAKPLDTVRKSYYSKDPS 433
L + P E+ SQL + EPG + L
Sbjct: 845 KKSPVTAELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSVL------------- 891
Query: 434 RAEKREIKCPTPGCD-GTGHVT 454
K E K P PG G G VT
Sbjct: 892 ---KSEPKPPGPGAGLGAGTVT 910
Score = 66.6 bits (161), Expect = 1e-10
Identities = 36/67 (53%), Positives = 45/67 (67%), Gaps = 4/67 (5%)
Query: 269 EEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPEL 328
+ + +EEEEEEEE+EEEEEE+EEEEEEEEEEEEEEE +E+ +A E+
Sbjct: 726 QPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEE----EEEEEAAAAVALGEV 781
Query: 329 RGPESPS 335
GP S S
Sbjct: 782 LGPRSGS 788
>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
Length = 587
Score = 81.3 bits (199), Expect = 5e-15
Identities = 54/134 (40%), Positives = 73/134 (54%), Gaps = 19/134 (14%)
Query: 236 CPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEE 295
C Q E +K LS ++EDEEEEEE EEEEE+ EEEEEE+EEEEEEEEEEEEE
Sbjct: 338 CEQLQEVLEGFNMAKVLASLS-DDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEE 396
Query: 296 EEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPES---------PSPK------PEY 340
E ++ + E+ A P ++ + + AP L P PSP+ P+
Sbjct: 397 EPQQRGQGEKSATPS---RKILDPNTGEPAPVLSSPPPADVSTFLAFPSPEKLLRLGPKS 453
Query: 341 SVIVEVRSDDDKDE 354
SV++ ++D E
Sbjct: 454 SVLIAQQTDTSDPE 467
Score = 52.8 bits (125), Expect = 2e-06
Identities = 29/71 (40%), Positives = 41/71 (57%)
Query: 219 EDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEE 278
E E++ EV + SL D EE ++ E E+EEEE+EEEEEEE+EEEE
Sbjct: 336 EGCEQLQEVLEGFNMAKVLASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEE 395
Query: 279 EEEEEEEEEEE 289
EE ++ + E+
Sbjct: 396 EEPQQRGQGEK 406
Score = 47.0 bits (110), Expect = 1e-04
Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 1/105 (0%)
Query: 239 SLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEE 298
++ +A ++++ +K L+ EE E+ +E E + ++E+EEEEEE EE
Sbjct: 312 AVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDDEDEEEEEEGEE 371
Query: 299 EEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVI 343
EEEE EEE D +E+ ++ P+ RG S P ++
Sbjct: 372 EEEEAEEEEEEDE-EEEEEEEEEEEEEPQQRGQGEKSATPSRKIL 415
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 79.3 bits (194), Expect = 2e-14
Identities = 59/155 (38%), Positives = 78/155 (50%), Gaps = 27/155 (17%)
Query: 205 AASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLED----AASEESSKQKGILSHEEE 260
AA E E+G+ PE E V E +D L+D A+ EE+ K +G H E
Sbjct: 471 AAVEVMEQGV---PEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEV 527
Query: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHT 320
E EEEEEEEEE+EE+EE EEEEEEE E E E +EE+E+ +E +D+ T
Sbjct: 528 KENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDE---------KDSGKT 578
Query: 321 SAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDED 355
+K P E S E SDDD+ ++
Sbjct: 579 LDKK-----------PSKEMSSDSEYDSDDDRTKE 602
Score = 45.8 bits (107), Expect = 2e-04
Identities = 49/241 (20%), Positives = 94/241 (39%), Gaps = 30/241 (12%)
Query: 92 DGSEDTE-----VKDAS-------VSDESEGTLEGAEAETSGQDEIHRPETAEGRSPVKS 139
DGSE+ E +K+ S DES+ L+ + + Q P G +
Sbjct: 162 DGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDA 221
Query: 140 HFGSNPIGSATASSKGSYSSYQGIIATSLLNLGQIAE---------------ETLVEEDL 184
F + A K + L L + E EE +
Sbjct: 222 SFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETV 281
Query: 185 GQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAA 244
G++ +E AE + E + + +D ++ E+ ++ + +
Sbjct: 282 KSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKE---KKKGPSK 338
Query: 245 SEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 304
+ + Q+ + +EE+E ++ EEEE + EE E + +EEE E+E+ E ++++E+E +
Sbjct: 339 ATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERK 398
Query: 305 E 305
E
Sbjct: 399 E 399
Score = 43.5 bits (101), Expect = 0.001
Identities = 29/127 (22%), Positives = 60/127 (47%), Gaps = 4/127 (3%)
Query: 205 AASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEE 264
A+ EE EK ++ V+ E ++ + ED SEE +++G S E +EE
Sbjct: 510 ASDEETEK---VEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGE-SEGSEGDEE 565
Query: 265 EEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQK 324
+E+ +E++ + +++ +E + E + +++ +EE + A I + H+
Sbjct: 566 DEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNVN 625
Query: 325 APELRGP 331
+LR P
Sbjct: 626 TEKLRAP 632
Score = 38.1 bits (87), Expect = 0.047
Identities = 69/343 (20%), Positives = 126/343 (36%), Gaps = 26/343 (7%)
Query: 44 KYSRHRSLQSCPLAKKRKLEGAEAEHLVSKRKSHPLKLALDEGYGVDSDGSEDTEVKDAS 103
K R R + AK RKL+ E E L + +K + + ++ S+ T D
Sbjct: 235 KKERERKKRDEEKAKLRKLK--EKEELETGKKDQSKQKESQRKFEEETVKSKVTV--DTG 290
Query: 104 VSDESEGTLEGAEAETSGQDEIHRPETAEGRSPVKSHFGSNPIGSATASSKGSYSSYQGI 163
V SE E AE T+ +D+ + + + K SK + + Q
Sbjct: 291 VIPASE---EKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEA 347
Query: 164 IATSLLNLGQIAEETLVEED-----LGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQP 218
+A L + E EE+ L + L QE E +E E+ ++
Sbjct: 348 LA----KLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKK 403
Query: 219 ED-----AEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEE 273
E ++ E + L + S++S +K + +++ ++ ++ E +E
Sbjct: 404 EGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEV 463
Query: 274 DEEEE-----EEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPEL 328
E E E E+ E+EE E EEEE+ E+ D T + ++
Sbjct: 464 SESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKV 523
Query: 329 RGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQD 371
+P+ E E D++ +E+ + E + +D
Sbjct: 524 HIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEED 566
>gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo
sapiens]
Length = 5033
Score = 78.2 bits (191), Expect = 4e-14
Identities = 55/148 (37%), Positives = 75/148 (50%), Gaps = 16/148 (10%)
Query: 259 EEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTS 318
EE+EEE+EEEE EEEDEEE+EE+EEE +E+E+EE+EEEE E E+EE + + Q
Sbjct: 1873 EEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEEGLLQ---- 1928
Query: 319 HTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRGNL 378
K PE S K + ++E D + S + + R
Sbjct: 1929 ----MKLPE-------SVKLQMCHLLEYFCDQELQHRVESLAAFAERYVDKLQANQRSRY 1977
Query: 379 GLLEQAIAL-KAEQVRTVCEPGCPPAEQ 405
GLL +A ++ AE R E PP EQ
Sbjct: 1978 GLLIKAFSMTAAETARRTREFRSPPQEQ 2005
Score = 58.2 bits (139), Expect = 4e-08
Identities = 30/61 (49%), Positives = 41/61 (67%), Gaps = 4/61 (6%)
Query: 237 PQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 296
P+ + EE +++G EEEDEEE+EE+EEE E+E+EE+EEEE E E+EE E
Sbjct: 1868 PEVFTEEEEEEDEEEEG----EEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLE 1923
Query: 297 E 297
E
Sbjct: 1924 E 1924
Score = 38.1 bits (87), Expect = 0.047
Identities = 40/131 (30%), Positives = 54/131 (41%), Gaps = 13/131 (9%)
Query: 185 GQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTT------ERSQDLCPQ 238
G+ A G G +AAEGA EE E P A+ V VT E + L
Sbjct: 4400 GEGASEGAG------DAAEGAGDEE-EAVHEAGPGGADGAVAVTDGGPFRPEGAGGLGDM 4452
Query: 239 SLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEE 298
A + + IL + + EEE E E E E E E E+ + E E+EE E
Sbjct: 4453 GDTTPAEPPTPEGSPILKRKLGVDGVEEELPPEPEPEPEPELEPEKADAENGEKEEVPEP 4512
Query: 299 EEEEEEEEAAP 309
E +++A P
Sbjct: 4513 TPEPPKKQAPP 4523
Score = 37.0 bits (84), Expect = 0.10
Identities = 22/68 (32%), Positives = 37/68 (54%), Gaps = 6/68 (8%)
Query: 219 EDAEEVVEV------TTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEE 272
ED ++++++ T E ++ + E+ EE + + + E+EDEE+EEEE E
Sbjct: 1857 EDVKQILKMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEG 1916
Query: 273 EDEEEEEE 280
E EE EE
Sbjct: 1917 EKEEGLEE 1924
Score = 34.3 bits (77), Expect = 0.68
Identities = 22/66 (33%), Positives = 29/66 (43%), Gaps = 14/66 (21%)
Query: 274 DEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPES 333
+EE E E E E E E E+ + E E+EE E P+ P+ + P S
Sbjct: 4479 EEELPPEPEPEPEPELEPEKADAENGEKEEVPEPTPE--------------PPKKQAPPS 4524
Query: 334 PSPKPE 339
P PK E
Sbjct: 4525 PPPKKE 4530
Score = 30.4 bits (67), Expect = 9.8
Identities = 25/70 (35%), Positives = 35/70 (50%), Gaps = 12/70 (17%)
Query: 274 DEEEEEEEEEEE---------EEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQK 324
D EEEE EEE E+ +++EE+ EEE EE+ P + QE SH +
Sbjct: 2047 DGEEEEPEEETTLGSRLMSLLEKVRLVKKKEEKPEEERSAEESKPRSL-QELVSHMVVRW 2105
Query: 325 APE--LRGPE 332
A E ++ PE
Sbjct: 2106 AQEDFVQSPE 2115
>gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo
sapiens]
Length = 5038
Score = 78.2 bits (191), Expect = 4e-14
Identities = 55/148 (37%), Positives = 75/148 (50%), Gaps = 16/148 (10%)
Query: 259 EEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTS 318
EE+EEE+EEEE EEEDEEE+EE+EEE +E+E+EE+EEEE E E+EE + + Q
Sbjct: 1873 EEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEEGLLQ---- 1928
Query: 319 HTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRGNL 378
K PE S K + ++E D + S + + R
Sbjct: 1929 ----MKLPE-------SVKLQMCHLLEYFCDQELQHRVESLAAFAERYVDKLQANQRSRY 1977
Query: 379 GLLEQAIAL-KAEQVRTVCEPGCPPAEQ 405
GLL +A ++ AE R E PP EQ
Sbjct: 1978 GLLIKAFSMTAAETARRTREFRSPPQEQ 2005
Score = 58.2 bits (139), Expect = 4e-08
Identities = 30/61 (49%), Positives = 41/61 (67%), Gaps = 4/61 (6%)
Query: 237 PQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 296
P+ + EE +++G EEEDEEE+EE+EEE E+E+EE+EEEE E E+EE E
Sbjct: 1868 PEVFTEEEEEEDEEEEG----EEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLE 1923
Query: 297 E 297
E
Sbjct: 1924 E 1924
Score = 38.1 bits (87), Expect = 0.047
Identities = 40/131 (30%), Positives = 54/131 (41%), Gaps = 13/131 (9%)
Query: 185 GQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTT------ERSQDLCPQ 238
G+ A G G +AAEGA EE E P A+ V VT E + L
Sbjct: 4405 GEGASEGAG------DAAEGAGDEE-EAVHEAGPGGADGAVAVTDGGPFRPEGAGGLGDM 4457
Query: 239 SLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEE 298
A + + IL + + EEE E E E E E E E+ + E E+EE E
Sbjct: 4458 GDTTPAEPPTPEGSPILKRKLGVDGVEEELPPEPEPEPEPELEPEKADAENGEKEEVPEP 4517
Query: 299 EEEEEEEEAAP 309
E +++A P
Sbjct: 4518 TPEPPKKQAPP 4528
Score = 37.0 bits (84), Expect = 0.10
Identities = 22/68 (32%), Positives = 37/68 (54%), Gaps = 6/68 (8%)
Query: 219 EDAEEVVEV------TTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEE 272
ED ++++++ T E ++ + E+ EE + + + E+EDEE+EEEE E
Sbjct: 1857 EDVKQILKMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEG 1916
Query: 273 EDEEEEEE 280
E EE EE
Sbjct: 1917 EKEEGLEE 1924
Score = 34.3 bits (77), Expect = 0.68
Identities = 22/66 (33%), Positives = 29/66 (43%), Gaps = 14/66 (21%)
Query: 274 DEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPES 333
+EE E E E E E E E+ + E E+EE E P+ P+ + P S
Sbjct: 4484 EEELPPEPEPEPEPELEPEKADAENGEKEEVPEPTPE--------------PPKKQAPPS 4529
Query: 334 PSPKPE 339
P PK E
Sbjct: 4530 PPPKKE 4535
Score = 30.4 bits (67), Expect = 9.8
Identities = 25/70 (35%), Positives = 35/70 (50%), Gaps = 12/70 (17%)
Query: 274 DEEEEEEEEEEE---------EEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQK 324
D EEEE EEE E+ +++EE+ EEE EE+ P + QE SH +
Sbjct: 2047 DGEEEEPEEETTLGSRLMSLLEKVRLVKKKEEKPEEERSAEESKPRSL-QELVSHMVVRW 2105
Query: 325 APE--LRGPE 332
A E ++ PE
Sbjct: 2106 AQEDFVQSPE 2115
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 78.2 bits (191), Expect = 4e-14
Identities = 52/131 (39%), Positives = 71/131 (54%), Gaps = 13/131 (9%)
Query: 218 PEDAEEVVEVTTERSQDLCPQSLEDAASEE-----------SSKQKGILSHEEED--EEE 264
P+ +E + R+ S E+ SEE SS ++G + EE+ EE+
Sbjct: 149 PDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEED 208
Query: 265 EEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQK 324
EE+EE EED EE+EE +E+ EEEEEEEEEEEEEEEEEEEE + +E+ + +
Sbjct: 209 VEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRS 268
Query: 325 APELRGPESPS 335
G ES S
Sbjct: 269 EASDSGSESVS 279
Score = 69.3 bits (168), Expect = 2e-11
Identities = 34/80 (42%), Positives = 50/80 (62%)
Query: 241 EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300
E+ E+ + + + EEDEE +E+ EEEEE+EEEEEEEEEEEEEE E++E +++EE
Sbjct: 202 EEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEG 261
Query: 301 EEEEEEAAPDVIFQEDTSHT 320
+ + + E S T
Sbjct: 262 NDYDTRSEASDSGSESVSFT 281
Score = 65.1 bits (157), Expect = 4e-10
Identities = 40/120 (33%), Positives = 65/120 (54%), Gaps = 19/120 (15%)
Query: 199 QEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHE 258
+ + G++ E+G E+ EE VE E +++ EDA +E E
Sbjct: 184 ETGSSGSSDEQGNN-----TENEEEGVEEDVEEDEEV----EEDAEEDE----------E 224
Query: 259 EEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTS 318
+++ EEEEEEEEEE+EEEEEEEEE E++E +++EE + + E ++ + + D S
Sbjct: 225 VDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGS 284
Score = 59.3 bits (142), Expect = 2e-08
Identities = 75/291 (25%), Positives = 110/291 (37%), Gaps = 33/291 (11%)
Query: 94 SEDTEVKDASVSDESEGTLEGAEAETSGQDEIHRPETAEGRSPVKSH-FGSNPIGSATAS 152
+E E D + ESE + D + +T + V S S P+ S+ ++
Sbjct: 21 TEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSN 80
Query: 153 SKGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKPGPGIVHLLQEAAEGAASEEGEK 212
+K S+ +G AT N E D + + L A+ + EK
Sbjct: 81 NKRIVST-KGKSATEYKNEEYQRSERNKRLDADRK-------IRLSSSASREPYKNQPEK 132
Query: 213 GLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEE------- 265
++ D E + T + ++ AS S K ++ EE + E
Sbjct: 133 TC-VRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSS 191
Query: 266 -EEEEEEEEDEEEEEEEEEEEEEEEEE-----------EEEEEEEEEEEEEEEAAPDVIF 313
E+ E +EE EE+ EE+EE EE+ EEEEEEEEEEEEEEE +
Sbjct: 192 DEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYE 251
Query: 314 QEDTSHTSAQKAPELRGPESPSPKPEYSVI-VEVRS---DDDKDEDTHSRK 360
Q++ + R S S S VRS D DE RK
Sbjct: 252 QDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERK 302
Score = 47.8 bits (112), Expect = 6e-05
Identities = 54/265 (20%), Positives = 99/265 (37%), Gaps = 35/265 (13%)
Query: 123 DEIHRPETAEGRSPVKSHFGSNPIGSATASSKGSYSSYQGIIATSLLNLGQIAEETLVEE 182
DE++ PE+ + ++ K + +T + + S + LV +
Sbjct: 28 DELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPS---------------VHSRQLVSK 72
Query: 183 DLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQD-------- 234
L + IV ++A +EE ++ + DA+ + +++ S++
Sbjct: 73 PLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEK 132
Query: 235 LC-----PQSLEDAASEESSKQKGI-----LSHEEEDEEEEEEEEEEEEDEEEEEEEEEE 284
C P+ + + + S++ G+ S + +EE EE D E +
Sbjct: 133 TCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSD 192
Query: 285 EEEEEEEEEEEEEEEEEEEEEEAAPDVIFQE--DTSHTSAQKAPELRGPESPSPKPEYSV 342
E+ E EEE EE+ EE+EE D E D ++ E E + EY
Sbjct: 193 EQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQ 252
Query: 343 IVEVRSDDDKDEDTHSRKSTVTDES 367
+ ++ D DT S S ES
Sbjct: 253 DERDQKEEGNDYDTRSEASDSGSES 277
Score = 32.7 bits (73), Expect = 2.0
Identities = 44/166 (26%), Positives = 64/166 (38%), Gaps = 14/166 (8%)
Query: 7 DKRARTRSKALRGP----PETTAADLSCP-----TPGCTGSGHVRGKYSRH--RSLQSCP 55
D++ R S A R P PE T P +P GS + + R RS QS
Sbjct: 112 DRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSK 171
Query: 56 LAKKRKLEGAEAEHLVSKRKSHPLKLALDEGYGVDSDGSEDTEVKDASVSDE---SEGTL 112
+ G++ E S +E GV+ D ED EV++ + DE +G
Sbjct: 172 EEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEE 231
Query: 113 EGAEAETSGQDEIHRPETAEGRSPVKSHFGSNPIGSATASSKGSYS 158
E E E ++E E E + G++ + AS GS S
Sbjct: 232 EEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSES 277
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 78.2 bits (191), Expect = 4e-14
Identities = 52/131 (39%), Positives = 71/131 (54%), Gaps = 13/131 (9%)
Query: 218 PEDAEEVVEVTTERSQDLCPQSLEDAASEE-----------SSKQKGILSHEEED--EEE 264
P+ +E + R+ S E+ SEE SS ++G + EE+ EE+
Sbjct: 149 PDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEED 208
Query: 265 EEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQK 324
EE+EE EED EE+EE +E+ EEEEEEEEEEEEEEEEEEEE + +E+ + +
Sbjct: 209 VEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRS 268
Query: 325 APELRGPESPS 335
G ES S
Sbjct: 269 EASDSGSESVS 279
Score = 69.3 bits (168), Expect = 2e-11
Identities = 34/80 (42%), Positives = 50/80 (62%)
Query: 241 EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300
E+ E+ + + + EEDEE +E+ EEEEE+EEEEEEEEEEEEEE E++E +++EE
Sbjct: 202 EEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEG 261
Query: 301 EEEEEEAAPDVIFQEDTSHT 320
+ + + E S T
Sbjct: 262 NDYDTRSEASDSGSESVSFT 281
Score = 65.1 bits (157), Expect = 4e-10
Identities = 40/120 (33%), Positives = 65/120 (54%), Gaps = 19/120 (15%)
Query: 199 QEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHE 258
+ + G++ E+G E+ EE VE E +++ EDA +E E
Sbjct: 184 ETGSSGSSDEQGNN-----TENEEEGVEEDVEEDEEV----EEDAEEDE----------E 224
Query: 259 EEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTS 318
+++ EEEEEEEEEE+EEEEEEEEE E++E +++EE + + E ++ + + D S
Sbjct: 225 VDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGS 284
Score = 59.3 bits (142), Expect = 2e-08
Identities = 75/291 (25%), Positives = 110/291 (37%), Gaps = 33/291 (11%)
Query: 94 SEDTEVKDASVSDESEGTLEGAEAETSGQDEIHRPETAEGRSPVKSH-FGSNPIGSATAS 152
+E E D + ESE + D + +T + V S S P+ S+ ++
Sbjct: 21 TEVPEQDDELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSN 80
Query: 153 SKGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKPGPGIVHLLQEAAEGAASEEGEK 212
+K S+ +G AT N E D + + L A+ + EK
Sbjct: 81 NKRIVST-KGKSATEYKNEEYQRSERNKRLDADRK-------IRLSSSASREPYKNQPEK 132
Query: 213 GLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEE------- 265
++ D E + T + ++ AS S K ++ EE + E
Sbjct: 133 TC-VRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSS 191
Query: 266 -EEEEEEEEDEEEEEEEEEEEEEEEEE-----------EEEEEEEEEEEEEEEAAPDVIF 313
E+ E +EE EE+ EE+EE EE+ EEEEEEEEEEEEEEE +
Sbjct: 192 DEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYE 251
Query: 314 QEDTSHTSAQKAPELRGPESPSPKPEYSVI-VEVRS---DDDKDEDTHSRK 360
Q++ + R S S S VRS D DE RK
Sbjct: 252 QDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDEKKKERK 302
Score = 47.8 bits (112), Expect = 6e-05
Identities = 54/265 (20%), Positives = 99/265 (37%), Gaps = 35/265 (13%)
Query: 123 DEIHRPETAEGRSPVKSHFGSNPIGSATASSKGSYSSYQGIIATSLLNLGQIAEETLVEE 182
DE++ PE+ + ++ K + +T + + S + LV +
Sbjct: 28 DELYNPESEQDKNEKKGSKRKSDRMESTDTKRQKPS---------------VHSRQLVSK 72
Query: 183 DLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQD-------- 234
L + IV ++A +EE ++ + DA+ + +++ S++
Sbjct: 73 PLSSSVSNNKRIVSTKGKSATEYKNEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEK 132
Query: 235 LC-----PQSLEDAASEESSKQKGI-----LSHEEEDEEEEEEEEEEEEDEEEEEEEEEE 284
C P+ + + + S++ G+ S + +EE EE D E +
Sbjct: 133 TCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSD 192
Query: 285 EEEEEEEEEEEEEEEEEEEEEEAAPDVIFQE--DTSHTSAQKAPELRGPESPSPKPEYSV 342
E+ E EEE EE+ EE+EE D E D ++ E E + EY
Sbjct: 193 EQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQ 252
Query: 343 IVEVRSDDDKDEDTHSRKSTVTDES 367
+ ++ D DT S S ES
Sbjct: 253 DERDQKEEGNDYDTRSEASDSGSES 277
Score = 32.7 bits (73), Expect = 2.0
Identities = 44/166 (26%), Positives = 64/166 (38%), Gaps = 14/166 (8%)
Query: 7 DKRARTRSKALRGP----PETTAADLSCP-----TPGCTGSGHVRGKYSRH--RSLQSCP 55
D++ R S A R P PE T P +P GS + + R RS QS
Sbjct: 112 DRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSK 171
Query: 56 LAKKRKLEGAEAEHLVSKRKSHPLKLALDEGYGVDSDGSEDTEVKDASVSDE---SEGTL 112
+ G++ E S +E GV+ D ED EV++ + DE +G
Sbjct: 172 EEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEE 231
Query: 113 EGAEAETSGQDEIHRPETAEGRSPVKSHFGSNPIGSATASSKGSYS 158
E E E ++E E E + G++ + AS GS S
Sbjct: 232 EEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSES 277
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 76.6 bits (187), Expect = 1e-13
Identities = 50/130 (38%), Positives = 67/130 (51%), Gaps = 14/130 (10%)
Query: 255 LSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEE--------EEEEEEEE-----EEEE 301
L E E+EEEEEEEEEEEE E EEEEEE EEEEEE EEEE EEE +EEE
Sbjct: 401 LKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEE 460
Query: 302 EEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKS 361
EE+EE++ + + ED + + G + + + + +D D D+
Sbjct: 461 EEDEESSSEGLEAEDWAQGVVEAGGSF-GAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDD 519
Query: 362 TVTDESEMQD 371
D+ + D
Sbjct: 520 EEEDDEDEDD 529
Score = 56.2 bits (134), Expect = 2e-07
Identities = 49/212 (23%), Positives = 88/212 (41%), Gaps = 41/212 (19%)
Query: 137 VKSHFGSNPIGSATASSKGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKP-----G 191
VK H+ + A A+ +G S + T L+ A + + D+ + G
Sbjct: 333 VKGHYRQAMLLKAMAALEGQDPSGLQLGLTEALHFVAAAWQAVEPSDIAACFREAGFGGG 392
Query: 192 PGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQ 251
P +EG EE E+ + + EE E E ++ E+ EE ++
Sbjct: 393 PNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEE--GGEGEELGEEEEVEE 450
Query: 252 KGILSHEEEDEEEEEEEEE--EEED--------------------------------EEE 277
+G + +EE+EE+EE E E ED E+
Sbjct: 451 EGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDS 510
Query: 278 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAP 309
+ + EEE++EEE++E+E+++++EE+ +E P
Sbjct: 511 DSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVP 542
Score = 33.5 bits (75), Expect = 1.2
Identities = 23/83 (27%), Positives = 37/83 (44%)
Query: 294 EEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKD 353
+ E EEEEEEEEE + E+ ++ E E + E +V SD++++
Sbjct: 402 KSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEE 461
Query: 354 EDTHSRKSTVTDESEMQDMMTRG 376
ED S + E Q ++ G
Sbjct: 462 EDEESSSEGLEAEDWAQGVVEAG 484
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 76.3 bits (186), Expect = 2e-13
Identities = 75/284 (26%), Positives = 127/284 (44%), Gaps = 46/284 (16%)
Query: 176 EETLVEEDLGQAAKPGPGIVHLLQEAAEGAASEE---------------GEKGLFIQPED 220
EE + EE+ A K I L + EG EE ++G + +
Sbjct: 2157 EEKMTEEESKLARKHSEVI---LDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKF 2213
Query: 221 AEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEE----EDEE 276
+ +V EV +E +SL D E KQ+ + S EEE+ EEEEE EEEE E+E
Sbjct: 2214 SSQVDEVESEEHFSEEMESLLD----ELEKQESLSSEEEEEREEEEEREEEEVREEEEER 2269
Query: 277 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSP 336
+EEEE EE++ E+EEEE++++++E+++EE + +F+E S ++ L
Sbjct: 2270 KEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESL-------- 2321
Query: 337 KPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVC 396
SD++++E++ S + V E E+ + L + E+V ++
Sbjct: 2322 -----------SDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRERVLSIL 2370
Query: 397 EPGCPPAEQSQLGLGEPGKAAKPLDTVRKSYYSKDPSRAEKREI 440
G P + + LG K L + K P +++I
Sbjct: 2371 R-GVPHGKGRAIRLGVLKSPLKKLMSTALEMKEKTPVPVPEKQI 2413
Score = 40.8 bits (94), Expect = 0.007
Identities = 34/127 (26%), Positives = 61/127 (48%), Gaps = 16/127 (12%)
Query: 197 LLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILS 256
LLQE E + GEK L + E +E ++ E + + L + E+ K + ++
Sbjct: 1489 LLQE--EEKLHQAGEK-LSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVT 1545
Query: 257 HEEEDEEEEEEEEEEEEDEEEEEEEE-------------EEEEEEEEEEEEEEEEEEEEE 303
EEE E EE+E++ +E+ +EE E++ +EE + +EEE+ +E
Sbjct: 1546 LEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQE 1605
Query: 304 EEEAAPD 310
E + A +
Sbjct: 1606 ERQLAQE 1612
Score = 38.5 bits (88), Expect = 0.036
Identities = 33/165 (20%), Positives = 68/165 (41%), Gaps = 18/165 (10%)
Query: 244 ASEESSKQKGILSHEEEDEEEE-----------EEEEEEEEDEEEEEEEEEEEEEEEEEE 292
A E+ S ++ +L +++ + EE + +E++ +DEEE EEE E EE+E
Sbjct: 1499 AGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKE 1558
Query: 293 EEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDK 352
++ EE+ +EE + H +A + R E E + + +
Sbjct: 1559 QQVTEEQRHIQEEHKWARI-------HRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQ 1611
Query: 353 DEDTHSRKSTVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCE 397
+E ++ + + + G E+ +A + E++ E
Sbjct: 1612 EERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAE 1656
Score = 37.4 bits (85), Expect = 0.080
Identities = 23/64 (35%), Positives = 39/64 (60%), Gaps = 3/64 (4%)
Query: 246 EESSKQKGILSHEEEDEEEEEEE---EEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEE 302
EE ++++G L E++ EEEE + E+ EEE + +EEE +E+E+ + +E+
Sbjct: 1733 EELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMP 1792
Query: 303 EEEE 306
EEEE
Sbjct: 1793 EEEE 1796
Score = 36.6 bits (83), Expect = 0.14
Identities = 57/229 (24%), Positives = 95/229 (41%), Gaps = 34/229 (14%)
Query: 100 KDASVSDESEGTLEGAEAETSGQDEIHRPETAEGRSPVKSHFGSNPIGSATASSKGSYSS 159
K+ DE E TLE E S + E + E + ++ I A ++ +
Sbjct: 1534 KEQQYKDEEEVTLE---EEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQ 1590
Query: 160 YQGIIATSLLNLGQIAEETLVEEDLGQAAKPGPGIVHLLQEAAEGAASE----EGEKGLF 215
+ +A L Q E L +E+ K V + Q+ E A +E + E+ L
Sbjct: 1591 EERKLAQEEEKLAQ-EERQLAQEE----RKLAQAYVKITQDDREMAQAEGKFAQKEETLA 1645
Query: 216 IQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKG--------ILSHEEED------ 261
+ E + E ++ + L + + A EE +KG IL+ + E+
Sbjct: 1646 QRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQ 1705
Query: 262 -----EEEEEEEEEEEEDEEEE---EEEEEEEEEEEEEEEEEEEEEEEE 302
E+E +E EE E + EE +EEE +EE + EE+++ EEEE
Sbjct: 1706 NLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEE 1754
Score = 36.2 bits (82), Expect = 0.18
Identities = 42/156 (26%), Positives = 74/156 (47%), Gaps = 7/156 (4%)
Query: 176 EETLVE--EDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQ 233
EETL + E L Q A+ L + E A EE + L + EV + ++ +
Sbjct: 1641 EETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEK--LAKKGGKLAEVKNILAQKVE 1698
Query: 234 DLCPQSLE--DAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEE 291
+L PQ + D +E +++ L + E+ +EEE +EE + EE+++ EEEE
Sbjct: 1699 EL-PQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALA 1757
Query: 292 EEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPE 327
+ E+ EEE + + +I +++ +K PE
Sbjct: 1758 WQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPE 1793
Score = 34.7 bits (78), Expect = 0.52
Identities = 29/92 (31%), Positives = 48/92 (52%), Gaps = 6/92 (6%)
Query: 211 EKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEE 270
EK L + E+ E +E + + ++L + E EE K L+ EEE + E+
Sbjct: 1711 EKELAQELEELEWDMEELSWKEEELNQE--EGKLVEEKKK----LAEEEEALAWQREKLS 1764
Query: 271 EEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEE 302
EEE + +EEE +E+E+ + +E+ EEEE
Sbjct: 1765 EEETKLAQEEELLIQEKEKLAQHKEKMPEEEE 1796
Score = 33.9 bits (76), Expect = 0.89
Identities = 49/210 (23%), Positives = 85/210 (40%), Gaps = 19/210 (9%)
Query: 238 QSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEE- 296
QS D + S+++ L+ +E+ ++ + + +EE+ EEE + + E
Sbjct: 2115 QSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEV 2174
Query: 297 ----EEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDK 352
EEE EEEE P + +K E + + P K S + EV S++
Sbjct: 2175 ILDDEEEGGIEEEEVIPFL-------KRRWRKRKEAKRGDKPKEKFS-SQVDEVESEEHF 2226
Query: 353 DEDTHSRKSTVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEPGC--PPAEQSQLGL 410
E+ S + DE E Q+ ++ E+ + E+VR E E+ Q+
Sbjct: 2227 SEEMES----LLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEK 2282
Query: 411 GEPGKAAKPLDTVRKSYYSKDPSRAEKREI 440
E K K + ++ K+ EK EI
Sbjct: 2283 EEEEKKKKKKEKKKEEVQEKEEVFEEKEEI 2312
Score = 31.6 bits (70), Expect = 4.4
Identities = 33/123 (26%), Positives = 42/123 (34%), Gaps = 15/123 (12%)
Query: 647 LSTKPQDLPSKSVDIEVDENGTLDLSMHKHRKRENAFPSSSSCSSS--PGVKSPDASQRH 704
L + DL S +E N L LS HR + AF S S +K P S+
Sbjct: 1016 LGMRATDLQILSTQVEQRLNENLTLS---HRDEKPAFSLDVSMPSELKSSLKPPTVSEES 1072
Query: 705 SSTSAPSSSMTSPQSSQASRQDEWDRPLDYTK----------PSRLREEEPEESEPAAHS 754
PS Q+ +W R L TK P L +E E+ P
Sbjct: 1073 EVAIKPSKGQRRGQAGVKKHSQKWLRGLKKTKERDSKQMSTEPGLLEDESGTEAAPIEME 1132
Query: 755 FAS 757
AS
Sbjct: 1133 EAS 1135
Score = 30.4 bits (67), Expect = 9.8
Identities = 25/122 (20%), Positives = 58/122 (47%), Gaps = 3/122 (2%)
Query: 251 QKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPD 310
+K +L EE+ + E+ EEE +E+++ + EE ++ E + +E++ ++E +
Sbjct: 1486 EKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEE--E 1543
Query: 311 VIFQEDTSHTSAQKAPELRGPESP-SPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEM 369
V +E+ S +K ++ + + +++ I R+ +K RK +E
Sbjct: 1544 VTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLA 1603
Query: 370 QD 371
Q+
Sbjct: 1604 QE 1605
Score = 30.4 bits (67), Expect = 9.8
Identities = 28/115 (24%), Positives = 49/115 (42%), Gaps = 3/115 (2%)
Query: 217 QPEDAEEVV---EVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEE 273
Q +D EEV EV+ E + + E +E K I E++ +EE +
Sbjct: 1537 QYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLA 1596
Query: 274 DEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPEL 328
EEE+ +EE + +EE + + + +++ E A T AQ+ +L
Sbjct: 1597 QEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKL 1651
Score = 30.4 bits (67), Expect = 9.8
Identities = 47/225 (20%), Positives = 92/225 (40%), Gaps = 20/225 (8%)
Query: 231 RSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEE------EEEEEEEE 284
+ ++ Q A EE + + ++D E + E + + EE E+ +E E
Sbjct: 1597 QEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAE 1656
Query: 285 EEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIV 344
+ ++ ++ ++ E+ EEE+ A + + AQK EL E E +
Sbjct: 1657 KLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQ 1716
Query: 345 EVRSDDDKDEDTHSRKSTVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEPGCPPAE 404
E+ + + D + S K ++ E + + + L E+A+A + E+ + E A+
Sbjct: 1717 EL-EELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREK---LSEEETKLAQ 1772
Query: 405 QSQLGLGEPGKAA----------KPLDTVRKSYYSKDPSRAEKRE 439
+ +L + E K A + L R+ K A+KRE
Sbjct: 1773 EEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRE 1817
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 76.3 bits (186), Expect = 2e-13
Identities = 49/119 (41%), Positives = 64/119 (53%), Gaps = 19/119 (15%)
Query: 233 QDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEE--- 289
QD+ + +++E SS + G S EEE+EEEEEEEE +E EEEEEEEEEEEEE
Sbjct: 255 QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGS 314
Query: 290 ----------EEEEEEEEEEEEEEEEE----AAPDVIFQEDTSHTSAQKAPELRGPESP 334
EE EEE E+EE E E P+ F D+ +++A E G +P
Sbjct: 315 NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSG--ESEEAEEEVGEGTP 371
Score = 71.2 bits (173), Expect = 5e-12
Identities = 50/158 (31%), Positives = 70/158 (44%), Gaps = 12/158 (7%)
Query: 220 DAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEE 279
D + V+ +DL + + SE + S E EEEEEEEEEE+EE
Sbjct: 235 DGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGST 294
Query: 280 EEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPE 339
EE EEEEEEEEEEEEE EE E + + + +E+ S E +
Sbjct: 295 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSE-----------DEERENENH 343
Query: 340 YSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRGN 377
V+ E R D D E + + V + + +T G+
Sbjct: 344 LLVVPESRFDRDSGESEEAEEE-VGEGTPQSSALTEGD 380
Score = 45.8 bits (107), Expect = 2e-04
Identities = 34/96 (35%), Positives = 44/96 (45%), Gaps = 19/96 (19%)
Query: 199 QEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHE 258
+E EG+ SEE E+ + E+ EE E T S++ QS E+ + EE S
Sbjct: 287 EEEEEGSTSEESEE----EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS--------- 333
Query: 259 EEDEEEEEEEE-----EEEEDEEEEEEEEEEEEEEE 289
EDEE E E E D + E EE EEE E
Sbjct: 334 -EDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 368
Score = 43.1 bits (100), Expect = 0.001
Identities = 28/103 (27%), Positives = 44/103 (42%)
Query: 201 AAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEE 260
+AE +++E G + E+ EE E +T + + E+ E S + E
Sbjct: 266 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 325
Query: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303
+ EEE E+EE + E E + + E EE EEE E
Sbjct: 326 EVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 368
Score = 37.7 bits (86), Expect = 0.062
Identities = 22/87 (25%), Positives = 36/87 (41%)
Query: 246 EESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305
+E K+K + +E E E + EE+D+ E E ++ E E E + E+ E
Sbjct: 102 DEKRKEKWKHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLER 161
Query: 306 EAAPDVIFQEDTSHTSAQKAPELRGPE 332
+ + +E QK E R E
Sbjct: 162 KRERERKMREQQKEQREQKERERRAEE 188
Score = 35.4 bits (80), Expect = 0.31
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
Query: 701 SQRHSSTSAPSSSMTSPQSSQASRQDEWDRPLDYTKPSRLREEEPEESEPAAHSFASSEA 760
S+R +S++ SS+ + S + ++E + T EEE EE E S EA
Sbjct: 260 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 319
Query: 761 DDQ---EVSEENFEE 772
+Q EVSEE E
Sbjct: 320 SEQSAEEVSEEEMSE 334
Score = 34.7 bits (78), Expect = 0.52
Identities = 41/209 (19%), Positives = 81/209 (38%), Gaps = 31/209 (14%)
Query: 222 EEVVEVTTERSQDLCPQSLEDAASEESS---KQKGILSHEEEDEEEEEEEEEE------- 271
+ +E+T S S+ED E+ S K +S +E+ ++E+ +E
Sbjct: 55 DHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARV 114
Query: 272 -EEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRG 330
E + E + EE+++ E E ++ E E D + Q + +K E +
Sbjct: 115 KEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQK 174
Query: 331 PESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRGNLGLLEQAIALKAE 390
+ + E R +++ ++ +R+ M++ + + +KA
Sbjct: 175 EQREQKERE-------RRAEERRKEREARREVSAHHRTMRE----------DYSDKVKAS 217
Query: 391 QVRTVCEPGCPPAEQSQLGLG-EPGKAAK 418
P PP E+ +LG G +P K K
Sbjct: 218 HWSR--SPPRPPRERFELGDGRKPVKEEK 244
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 76.3 bits (186), Expect = 2e-13
Identities = 49/119 (41%), Positives = 64/119 (53%), Gaps = 19/119 (15%)
Query: 233 QDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEE--- 289
QD+ + +++E SS + G S EEE+EEEEEEEE +E EEEEEEEEEEEEE
Sbjct: 265 QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGS 324
Query: 290 ----------EEEEEEEEEEEEEEEEE----AAPDVIFQEDTSHTSAQKAPELRGPESP 334
EE EEE E+EE E E P+ F D+ +++A E G +P
Sbjct: 325 NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSG--ESEEAEEEVGEGTP 381
Score = 71.2 bits (173), Expect = 5e-12
Identities = 50/158 (31%), Positives = 70/158 (44%), Gaps = 12/158 (7%)
Query: 220 DAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEE 279
D + V+ +DL + + SE + S E EEEEEEEEEE+EE
Sbjct: 245 DGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGST 304
Query: 280 EEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPE 339
EE EEEEEEEEEEEEE EE E + + + +E+ S E +
Sbjct: 305 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSE-----------DEERENENH 353
Query: 340 YSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRGN 377
V+ E R D D E + + V + + +T G+
Sbjct: 354 LLVVPESRFDRDSGESEEAEEE-VGEGTPQSSALTEGD 390
Score = 45.8 bits (107), Expect = 2e-04
Identities = 34/96 (35%), Positives = 44/96 (45%), Gaps = 19/96 (19%)
Query: 199 QEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHE 258
+E EG+ SEE E+ + E+ EE E T S++ QS E+ + EE S
Sbjct: 297 EEEEEGSTSEESEE----EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS--------- 343
Query: 259 EEDEEEEEEEE-----EEEEDEEEEEEEEEEEEEEE 289
EDEE E E E D + E EE EEE E
Sbjct: 344 -EDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 378
Score = 43.1 bits (100), Expect = 0.001
Identities = 28/103 (27%), Positives = 44/103 (42%)
Query: 201 AAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEE 260
+AE +++E G + E+ EE E +T + + E+ E S + E
Sbjct: 276 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 335
Query: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303
+ EEE E+EE + E E + + E EE EEE E
Sbjct: 336 EVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 378
Score = 35.4 bits (80), Expect = 0.31
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
Query: 701 SQRHSSTSAPSSSMTSPQSSQASRQDEWDRPLDYTKPSRLREEEPEESEPAAHSFASSEA 760
S+R +S++ SS+ + S + ++E + T EEE EE E S EA
Sbjct: 270 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 329
Query: 761 DDQ---EVSEENFEE 772
+Q EVSEE E
Sbjct: 330 SEQSAEEVSEEEMSE 344
Score = 34.3 bits (77), Expect = 0.68
Identities = 31/136 (22%), Positives = 52/136 (38%), Gaps = 13/136 (9%)
Query: 203 EGAASEEGEK--GLFIQPEDA----EEVVEVTTERSQDLCPQSLEDAASEESSKQKGILS 256
E + + GE+ L I+P E+V E+ ++ C A + ++ K
Sbjct: 70 EDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGKHARVKE-RE 128
Query: 257 HEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQED 316
HE EE+++ E E ++ E E E + E+ E + E E + +E
Sbjct: 129 HERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERK------MREQ 182
Query: 317 TSHTSAQKAPELRGPE 332
QK E R E
Sbjct: 183 QKEQREQKERERRAEE 198
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 76.3 bits (186), Expect = 2e-13
Identities = 49/119 (41%), Positives = 64/119 (53%), Gaps = 19/119 (15%)
Query: 233 QDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEE--- 289
QD+ + +++E SS + G S EEE+EEEEEEEE +E EEEEEEEEEEEEE
Sbjct: 256 QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGS 315
Query: 290 ----------EEEEEEEEEEEEEEEEE----AAPDVIFQEDTSHTSAQKAPELRGPESP 334
EE EEE E+EE E E P+ F D+ +++A E G +P
Sbjct: 316 NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSG--ESEEAEEEVGEGTP 372
Score = 71.2 bits (173), Expect = 5e-12
Identities = 50/158 (31%), Positives = 70/158 (44%), Gaps = 12/158 (7%)
Query: 220 DAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEE 279
D + V+ +DL + + SE + S E EEEEEEEEEE+EE
Sbjct: 236 DGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGST 295
Query: 280 EEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPE 339
EE EEEEEEEEEEEEE EE E + + + +E+ S E +
Sbjct: 296 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSE-----------DEERENENH 344
Query: 340 YSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRGN 377
V+ E R D D E + + V + + +T G+
Sbjct: 345 LLVVPESRFDRDSGESEEAEEE-VGEGTPQSSALTEGD 381
Score = 45.8 bits (107), Expect = 2e-04
Identities = 34/96 (35%), Positives = 44/96 (45%), Gaps = 19/96 (19%)
Query: 199 QEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHE 258
+E EG+ SEE E+ + E+ EE E T S++ QS E+ + EE S
Sbjct: 288 EEEEEGSTSEESEE----EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS--------- 334
Query: 259 EEDEEEEEEEE-----EEEEDEEEEEEEEEEEEEEE 289
EDEE E E E D + E EE EEE E
Sbjct: 335 -EDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 369
Score = 43.1 bits (100), Expect = 0.001
Identities = 28/103 (27%), Positives = 44/103 (42%)
Query: 201 AAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEE 260
+AE +++E G + E+ EE E +T + + E+ E S + E
Sbjct: 267 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 326
Query: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303
+ EEE E+EE + E E + + E EE EEE E
Sbjct: 327 EVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 369
Score = 38.9 bits (89), Expect = 0.028
Identities = 21/87 (24%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
Query: 222 EEVVEVTTERSQDLCPQSLEDAASEESS---KQKGILSHEEEDEEEEEEEEEEEEDEEEE 278
+ +E+T S S+ED E+ S K +S +E+ ++E+ +E++ +
Sbjct: 55 DHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVK 114
Query: 279 EEEEEEEEEEEEEEEEEEEEEEEEEEE 305
E+E E E + EE+++ E E ++
Sbjct: 115 EKEREHERRKRHREEQDKARREWERQK 141
Score = 37.7 bits (86), Expect = 0.062
Identities = 22/87 (25%), Positives = 36/87 (41%)
Query: 246 EESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305
E+ ++K E+E E E + EE+D+ E E ++ E E E + E+ E
Sbjct: 103 EKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLER 162
Query: 306 EAAPDVIFQEDTSHTSAQKAPELRGPE 332
+ + +E QK E R E
Sbjct: 163 KRERERKMREQQKEQREQKERERRAEE 189
Score = 35.4 bits (80), Expect = 0.31
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
Query: 701 SQRHSSTSAPSSSMTSPQSSQASRQDEWDRPLDYTKPSRLREEEPEESEPAAHSFASSEA 760
S+R +S++ SS+ + S + ++E + T EEE EE E S EA
Sbjct: 261 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 320
Query: 761 DDQ---EVSEENFEE 772
+Q EVSEE E
Sbjct: 321 SEQSAEEVSEEEMSE 335
Score = 31.6 bits (70), Expect = 4.4
Identities = 37/221 (16%), Positives = 81/221 (36%), Gaps = 19/221 (8%)
Query: 217 QPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEED-- 274
+ E+ E+ + +D SLE+ + + I + E+ E+ EE++
Sbjct: 25 EQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLA 84
Query: 275 ----------------EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTS 318
++E+ +E++ +E+E E E + EE+++A + Q+
Sbjct: 85 IKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRRE 144
Query: 319 HTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRGNL 378
E E K E + + + +++ R++ + +
Sbjct: 145 MAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHH 204
Query: 379 GLLEQAIALKAEQVRTVCEPGCPPAEQSQLGLG-EPGKAAK 418
+ + + K + P PP E+ +LG G +P K K
Sbjct: 205 RTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEK 245
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 76.3 bits (186), Expect = 2e-13
Identities = 49/119 (41%), Positives = 64/119 (53%), Gaps = 19/119 (15%)
Query: 233 QDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEE--- 289
QD+ + +++E SS + G S EEE+EEEEEEEE +E EEEEEEEEEEEEE
Sbjct: 265 QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGS 324
Query: 290 ----------EEEEEEEEEEEEEEEEE----AAPDVIFQEDTSHTSAQKAPELRGPESP 334
EE EEE E+EE E E P+ F D+ +++A E G +P
Sbjct: 325 NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSG--ESEEAEEEVGEGTP 381
Score = 71.2 bits (173), Expect = 5e-12
Identities = 50/158 (31%), Positives = 70/158 (44%), Gaps = 12/158 (7%)
Query: 220 DAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEE 279
D + V+ +DL + + SE + S E EEEEEEEEEE+EE
Sbjct: 245 DGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGST 304
Query: 280 EEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPE 339
EE EEEEEEEEEEEEE EE E + + + +E+ S E +
Sbjct: 305 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSE-----------DEERENENH 353
Query: 340 YSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRGN 377
V+ E R D D E + + V + + +T G+
Sbjct: 354 LLVVPESRFDRDSGESEEAEEE-VGEGTPQSSALTEGD 390
Score = 45.8 bits (107), Expect = 2e-04
Identities = 34/96 (35%), Positives = 44/96 (45%), Gaps = 19/96 (19%)
Query: 199 QEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHE 258
+E EG+ SEE E+ + E+ EE E T S++ QS E+ + EE S
Sbjct: 297 EEEEEGSTSEESEE----EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS--------- 343
Query: 259 EEDEEEEEEEE-----EEEEDEEEEEEEEEEEEEEE 289
EDEE E E E D + E EE EEE E
Sbjct: 344 -EDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 378
Score = 43.1 bits (100), Expect = 0.001
Identities = 28/103 (27%), Positives = 44/103 (42%)
Query: 201 AAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEE 260
+AE +++E G + E+ EE E +T + + E+ E S + E
Sbjct: 276 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 335
Query: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303
+ EEE E+EE + E E + + E EE EEE E
Sbjct: 336 EVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 378
Score = 37.0 bits (84), Expect = 0.10
Identities = 22/93 (23%), Positives = 42/93 (45%), Gaps = 14/93 (15%)
Query: 222 EEVVEVTTERSQDLCPQSLEDAASEESS-----------KQKGILSHEEEDEEEEEEEEE 270
+ +E+T S S+ED E+ S K+K H +DE+ +E++
Sbjct: 55 DHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEK---VHHRKDEKRKEKKHA 111
Query: 271 EEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303
+++E E E + EE+++ E E ++ E
Sbjct: 112 RVKEKEREHERRKRHREEQDKARREWERQKRRE 144
Score = 35.4 bits (80), Expect = 0.31
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
Query: 701 SQRHSSTSAPSSSMTSPQSSQASRQDEWDRPLDYTKPSRLREEEPEESEPAAHSFASSEA 760
S+R +S++ SS+ + S + ++E + T EEE EE E S EA
Sbjct: 270 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 329
Query: 761 DDQ---EVSEENFEE 772
+Q EVSEE E
Sbjct: 330 SEQSAEEVSEEEMSE 344
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 76.3 bits (186), Expect = 2e-13
Identities = 49/119 (41%), Positives = 64/119 (53%), Gaps = 19/119 (15%)
Query: 233 QDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEE--- 289
QD+ + +++E SS + G S EEE+EEEEEEEE +E EEEEEEEEEEEEE
Sbjct: 233 QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGS 292
Query: 290 ----------EEEEEEEEEEEEEEEEE----AAPDVIFQEDTSHTSAQKAPELRGPESP 334
EE EEE E+EE E E P+ F D+ +++A E G +P
Sbjct: 293 NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSG--ESEEAEEEVGEGTP 349
Score = 71.2 bits (173), Expect = 5e-12
Identities = 50/158 (31%), Positives = 70/158 (44%), Gaps = 12/158 (7%)
Query: 220 DAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEE 279
D + V+ +DL + + SE + S E EEEEEEEEEE+EE
Sbjct: 213 DGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGST 272
Query: 280 EEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPE 339
EE EEEEEEEEEEEEE EE E + + + +E+ S E +
Sbjct: 273 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSE-----------DEERENENH 321
Query: 340 YSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRGN 377
V+ E R D D E + + V + + +T G+
Sbjct: 322 LLVVPESRFDRDSGESEEAEEE-VGEGTPQSSALTEGD 358
Score = 45.8 bits (107), Expect = 2e-04
Identities = 34/96 (35%), Positives = 44/96 (45%), Gaps = 19/96 (19%)
Query: 199 QEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHE 258
+E EG+ SEE E+ + E+ EE E T S++ QS E+ + EE S
Sbjct: 265 EEEEEGSTSEESEE----EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS--------- 311
Query: 259 EEDEEEEEEEE-----EEEEDEEEEEEEEEEEEEEE 289
EDEE E E E D + E EE EEE E
Sbjct: 312 -EDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 346
Score = 43.1 bits (100), Expect = 0.001
Identities = 28/103 (27%), Positives = 44/103 (42%)
Query: 201 AAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEE 260
+AE +++E G + E+ EE E +T + + E+ E S + E
Sbjct: 244 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 303
Query: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303
+ EEE E+EE + E E + + E EE EEE E
Sbjct: 304 EVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 346
Score = 36.2 bits (82), Expect = 0.18
Identities = 20/75 (26%), Positives = 31/75 (41%)
Query: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDT 317
E+E E E + EE+D+ E E ++ E E E + E+ E + + +E
Sbjct: 92 EKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQ 151
Query: 318 SHTSAQKAPELRGPE 332
QK E R E
Sbjct: 152 KEQREQKERERRAEE 166
Score = 35.4 bits (80), Expect = 0.31
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
Query: 701 SQRHSSTSAPSSSMTSPQSSQASRQDEWDRPLDYTKPSRLREEEPEESEPAAHSFASSEA 760
S+R +S++ SS+ + S + ++E + T EEE EE E S EA
Sbjct: 238 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 297
Query: 761 DDQ---EVSEENFEE 772
+Q EVSEE E
Sbjct: 298 SEQSAEEVSEEEMSE 312
Score = 34.3 bits (77), Expect = 0.68
Identities = 43/214 (20%), Positives = 79/214 (36%), Gaps = 35/214 (16%)
Query: 225 VEVTTERSQDLCPQSLEDAASEESS-----------KQKGILSHEEEDEEEEEEEEEEEE 273
+E+T S S+ED E+ S K+K H +DE+ +E+
Sbjct: 24 MEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEK---VHHRKDEKRKEKRRHRSH 80
Query: 274 DEE--------EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKA 325
E E+E E E + EE+++ E E ++ E A + +E ++
Sbjct: 81 SAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERK 140
Query: 326 PELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRGNLGLLEQAI 385
E K + R +++ ++ +R+ M++ + +
Sbjct: 141 RERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRE----------DYSD 190
Query: 386 ALKAEQVRTVCEPGCPPAEQSQLGLG-EPGKAAK 418
+KA P PP E+ +LG G +P K K
Sbjct: 191 KVKASHWSR--SPPRPPRERFELGDGRKPVKEEK 222
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 76.3 bits (186), Expect = 2e-13
Identities = 49/119 (41%), Positives = 64/119 (53%), Gaps = 19/119 (15%)
Query: 233 QDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEE--- 289
QD+ + +++E SS + G S EEE+EEEEEEEE +E EEEEEEEEEEEEE
Sbjct: 222 QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGS 281
Query: 290 ----------EEEEEEEEEEEEEEEEE----AAPDVIFQEDTSHTSAQKAPELRGPESP 334
EE EEE E+EE E E P+ F D+ +++A E G +P
Sbjct: 282 NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSG--ESEEAEEEVGEGTP 338
Score = 71.2 bits (173), Expect = 5e-12
Identities = 50/158 (31%), Positives = 70/158 (44%), Gaps = 12/158 (7%)
Query: 220 DAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEE 279
D + V+ +DL + + SE + S E EEEEEEEEEE+EE
Sbjct: 202 DGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGST 261
Query: 280 EEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPE 339
EE EEEEEEEEEEEEE EE E + + + +E+ S E +
Sbjct: 262 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSE-----------DEERENENH 310
Query: 340 YSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRGN 377
V+ E R D D E + + V + + +T G+
Sbjct: 311 LLVVPESRFDRDSGESEEAEEE-VGEGTPQSSALTEGD 347
Score = 45.8 bits (107), Expect = 2e-04
Identities = 34/96 (35%), Positives = 44/96 (45%), Gaps = 19/96 (19%)
Query: 199 QEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHE 258
+E EG+ SEE E+ + E+ EE E T S++ QS E+ + EE S
Sbjct: 254 EEEEEGSTSEESEE----EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS--------- 300
Query: 259 EEDEEEEEEEE-----EEEEDEEEEEEEEEEEEEEE 289
EDEE E E E D + E EE EEE E
Sbjct: 301 -EDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 335
Score = 43.1 bits (100), Expect = 0.001
Identities = 28/103 (27%), Positives = 44/103 (42%)
Query: 201 AAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEE 260
+AE +++E G + E+ EE E +T + + E+ E S + E
Sbjct: 233 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 292
Query: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303
+ EEE E+EE + E E + + E EE EEE E
Sbjct: 293 EVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 335
Score = 38.5 bits (88), Expect = 0.036
Identities = 21/84 (25%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Query: 225 VEVTTERSQDLCPQSLEDAASEESS---KQKGILSHEEEDEEEEEEEEEEEEDEEEEEEE 281
+E+T S S+ED E+ S K +S +E+ ++E+ +E++ +E+E
Sbjct: 24 MEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKE 83
Query: 282 EEEEEEEEEEEEEEEEEEEEEEEE 305
E E + EE+++ E E ++
Sbjct: 84 REHERRKRHREEQDKARREWERQK 107
Score = 37.7 bits (86), Expect = 0.062
Identities = 22/87 (25%), Positives = 36/87 (41%)
Query: 246 EESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305
E+ ++K E+E E E + EE+D+ E E ++ E E E + E+ E
Sbjct: 69 EKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLER 128
Query: 306 EAAPDVIFQEDTSHTSAQKAPELRGPE 332
+ + +E QK E R E
Sbjct: 129 KRERERKMREQQKEQREQKERERRAEE 155
Score = 35.4 bits (80), Expect = 0.31
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
Query: 701 SQRHSSTSAPSSSMTSPQSSQASRQDEWDRPLDYTKPSRLREEEPEESEPAAHSFASSEA 760
S+R +S++ SS+ + S + ++E + T EEE EE E S EA
Sbjct: 227 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 286
Query: 761 DDQ---EVSEENFEE 772
+Q EVSEE E
Sbjct: 287 SEQSAEEVSEEEMSE 301
>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
3 [Homo sapiens]
Length = 526
Score = 76.3 bits (186), Expect = 2e-13
Identities = 49/119 (41%), Positives = 64/119 (53%), Gaps = 19/119 (15%)
Query: 233 QDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEE--- 289
QD+ + +++E SS + G S EEE+EEEEEEEE +E EEEEEEEEEEEEE
Sbjct: 11 QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGS 70
Query: 290 ----------EEEEEEEEEEEEEEEEE----AAPDVIFQEDTSHTSAQKAPELRGPESP 334
EE EEE E+EE E E P+ F D+ +++A E G +P
Sbjct: 71 NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSG--ESEEAEEEVGEGTP 127
Score = 68.9 bits (167), Expect = 2e-11
Identities = 47/139 (33%), Positives = 63/139 (45%), Gaps = 13/139 (9%)
Query: 240 LEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEE 299
L+D + E S E EEEEEEEEE+EEE EE EEEEEEEEEEEEE
Sbjct: 10 LQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETG 69
Query: 300 EEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDE-DTHS 358
EE S SA++ E E + E ++V S D+D ++
Sbjct: 70 SNSEE------------ASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEE 117
Query: 359 RKSTVTDESEMQDMMTRGN 377
+ V + + +T G+
Sbjct: 118 AEEEVGEGTPQSSALTEGD 136
Score = 49.7 bits (117), Expect = 2e-05
Identities = 37/111 (33%), Positives = 51/111 (45%), Gaps = 13/111 (11%)
Query: 201 AAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHE-- 258
A G+ SEE E + E+ EE T+E S++ E+ EE ++ G S E
Sbjct: 28 AESGSGSEEEE-----EEEEEEEEEGSTSEESEE------EEEEEEEEEEETGSNSEEAS 76
Query: 259 EEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAP 309
E+ EE EEE E++E E E E + + E EE EEE E P
Sbjct: 77 EQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTP 127
Score = 45.8 bits (107), Expect = 2e-04
Identities = 34/96 (35%), Positives = 44/96 (45%), Gaps = 19/96 (19%)
Query: 199 QEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHE 258
+E EG+ SEE E+ + E+ EE E T S++ QS E+ + EE S
Sbjct: 43 EEEEEGSTSEESEE----EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS--------- 89
Query: 259 EEDEEEEEEEE-----EEEEDEEEEEEEEEEEEEEE 289
EDEE E E E D + E EE EEE E
Sbjct: 90 -EDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 124
Score = 43.1 bits (100), Expect = 0.001
Identities = 28/103 (27%), Positives = 44/103 (42%)
Query: 201 AAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEE 260
+AE +++E G + E+ EE E +T + + E+ E S + E
Sbjct: 22 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 81
Query: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303
+ EEE E+EE + E E + + E EE EEE E
Sbjct: 82 EVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 124
Score = 35.0 bits (79), Expect = 0.40
Identities = 26/76 (34%), Positives = 38/76 (50%), Gaps = 5/76 (6%)
Query: 701 SQRHSSTSAPSSSMTSPQSSQASRQDEWDRPLDYTKPSRLREEE----PEESEPAAHSFA 756
S+R +S SA SSS S S+ ++E + + + EEE EE E ++S
Sbjct: 16 SERKTS-SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEE 74
Query: 757 SSEADDQEVSEENFEE 772
+SE +EVSEE E
Sbjct: 75 ASEQSAEEVSEEEMSE 90
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 76.3 bits (186), Expect = 2e-13
Identities = 49/119 (41%), Positives = 64/119 (53%), Gaps = 19/119 (15%)
Query: 233 QDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEE--- 289
QD+ + +++E SS + G S EEE+EEEEEEEE +E EEEEEEEEEEEEE
Sbjct: 267 QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGS 326
Query: 290 ----------EEEEEEEEEEEEEEEEE----AAPDVIFQEDTSHTSAQKAPELRGPESP 334
EE EEE E+EE E E P+ F D+ +++A E G +P
Sbjct: 327 NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSG--ESEEAEEEVGEGTP 383
Score = 71.2 bits (173), Expect = 5e-12
Identities = 50/158 (31%), Positives = 70/158 (44%), Gaps = 12/158 (7%)
Query: 220 DAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEE 279
D + V+ +DL + + SE + S E EEEEEEEEEE+EE
Sbjct: 247 DGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGST 306
Query: 280 EEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPE 339
EE EEEEEEEEEEEEE EE E + + + +E+ S E +
Sbjct: 307 SEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSE-----------DEERENENH 355
Query: 340 YSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRGN 377
V+ E R D D E + + V + + +T G+
Sbjct: 356 LLVVPESRFDRDSGESEEAEEE-VGEGTPQSSALTEGD 392
Score = 45.8 bits (107), Expect = 2e-04
Identities = 34/96 (35%), Positives = 44/96 (45%), Gaps = 19/96 (19%)
Query: 199 QEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHE 258
+E EG+ SEE E+ + E+ EE E T S++ QS E+ + EE S
Sbjct: 299 EEEEEGSTSEESEE----EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMS--------- 345
Query: 259 EEDEEEEEEEE-----EEEEDEEEEEEEEEEEEEEE 289
EDEE E E E D + E EE EEE E
Sbjct: 346 -EDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 380
Score = 43.1 bits (100), Expect = 0.001
Identities = 28/103 (27%), Positives = 44/103 (42%)
Query: 201 AAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEE 260
+AE +++E G + E+ EE E +T + + E+ E S + E
Sbjct: 278 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 337
Query: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303
+ EEE E+EE + E E + + E EE EEE E
Sbjct: 338 EVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 380
Score = 36.2 bits (82), Expect = 0.18
Identities = 20/75 (26%), Positives = 31/75 (41%)
Query: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDT 317
E+E E E + EE+D+ E E ++ E E E + E+ E + + +E
Sbjct: 126 EKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQ 185
Query: 318 SHTSAQKAPELRGPE 332
QK E R E
Sbjct: 186 KEQREQKERERRAEE 200
Score = 35.4 bits (80), Expect = 0.31
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
Query: 701 SQRHSSTSAPSSSMTSPQSSQASRQDEWDRPLDYTKPSRLREEEPEESEPAAHSFASSEA 760
S+R +S++ SS+ + S + ++E + T EEE EE E S EA
Sbjct: 272 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 331
Query: 761 DDQ---EVSEENFEE 772
+Q EVSEE E
Sbjct: 332 SEQSAEEVSEEEMSE 346
Score = 34.3 bits (77), Expect = 0.68
Identities = 43/214 (20%), Positives = 79/214 (36%), Gaps = 35/214 (16%)
Query: 225 VEVTTERSQDLCPQSLEDAASEESS-----------KQKGILSHEEEDEEEEEEEEEEEE 273
+E+T S S+ED E+ S K+K H +DE+ +E+
Sbjct: 58 MEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEK---VHHRKDEKRKEKRRHRSH 114
Query: 274 DEE--------EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKA 325
E E+E E E + EE+++ E E ++ E A + +E ++
Sbjct: 115 SAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERK 174
Query: 326 PELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRGNLGLLEQAI 385
E K + R +++ ++ +R+ M++ + +
Sbjct: 175 RERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRE----------DYSD 224
Query: 386 ALKAEQVRTVCEPGCPPAEQSQLGLG-EPGKAAK 418
+KA P PP E+ +LG G +P K K
Sbjct: 225 KVKASHWSR--SPPRPPRERFELGDGRKPVKEEK 256
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 76.3 bits (186), Expect = 2e-13
Identities = 70/254 (27%), Positives = 106/254 (41%), Gaps = 18/254 (7%)
Query: 94 SEDTEVKDASVSDESEGTLEGAEAETSGQDEIHRPETAEGRSPVKSHFGSNPIGSATASS 153
S ++ + SD +G EGAE E EI P +A + + TA+
Sbjct: 348 SSPSQTPSSHDSDTRDGPEEGAEEEPPQVLEIKPPPSAVTQRNKQPWHPDEDDEEFTANE 407
Query: 154 KGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKPGP-GIVHLLQEAAEGAASEEGEK 212
+ + I A Q+ E +L + A+ G + LLQ+ A A G
Sbjct: 408 EEAEDEEDTIAAEE-----QLEGEVDHAMELSELAREGELSMEELLQQYAGAYAPGSGSS 462
Query: 213 GLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEE 272
+ ED +EV + + + P E+ E+SS Q + EDEE+E EEEE
Sbjct: 463 ----EDEDEDEV-DANSSDCEPEGPVEAEEPPQEDSSSQSDSVEDRSEDEEDEHSEEEET 517
Query: 273 EDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE---EEEAAPDVIFQEDTSHTSAQKAPELR 329
EE E EE E+ + + + +EEEE+++ E A D E+ S A P
Sbjct: 518 SGSSASEESESEESEDAQSQSQADEEEEDDDFGVEYLLARD----EEQSEADAGSGPPTP 573
Query: 330 GPESPSPKPEYSVI 343
GP + PK E + I
Sbjct: 574 GPTTLGPKKEITDI 587
Score = 48.9 bits (115), Expect = 3e-05
Identities = 71/293 (24%), Positives = 115/293 (39%), Gaps = 41/293 (13%)
Query: 90 DSDGS---EDTEVKDASVSDESEGTLEGAEAETSGQD-EIHRPETAEGRSPVKSHFGSNP 145
D DG ++ E +D + E E EG +AE ++ E+ R EG P++ S P
Sbjct: 284 DEDGDFQPQEDEEEDDEETIEVEEQQEGNDAEAQRREIELLR---REGELPLEELLRSLP 340
Query: 146 IGSATASSKGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAA--KPGPGIV-------- 195
S S + T + E EE+ Q KP P V
Sbjct: 341 PQLLEGPSSPSQTPSSHDSDT------RDGPEEGAEEEPPQVLEIKPPPSAVTQRNKQPW 394
Query: 196 HLLQEAAEGAASEEGEKGLFIQPED---AEEVVEVTTERSQDLCPQSLEDAASEESSKQK 252
H ++ E A+EE + ED AEE +E + + +L + E S E Q+
Sbjct: 395 HPDEDDEEFTANEEEAE----DEEDTIAAEEQLEGEVDHAMELSELAREGELSMEELLQQ 450
Query: 253 -------GILSHEEEDEEEEEEE----EEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEE 301
G S E+EDE+E + E E E EE +E+ + + E+ E+EE+E
Sbjct: 451 YAGAYAPGSGSSEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDSVEDRSEDEEDE 510
Query: 302 EEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDE 354
EEE E++ ++ A + ++ V + D+++ E
Sbjct: 511 HSEEEETSGSSASEESESEESEDAQSQSQADEEEEDDDFGVEYLLARDEEQSE 563
Score = 44.7 bits (104), Expect = 5e-04
Identities = 46/176 (26%), Positives = 69/176 (39%), Gaps = 36/176 (20%)
Query: 229 TERSQDLCPQSLED--------------AASEESSKQKGILSHEEEDEEEEEEEEEEEED 274
TE+ DL QSL ++S SS ++ED + + +E+EEE+D
Sbjct: 240 TEKYSDLLSQSLNQPLTSSKAGSSPCLGSSSAASSPPPPASRLDDEDGDFQPQEDEEEDD 299
Query: 275 EEEEEEEEEEEEEEEEEEEEEEEEEEEEEE---EE----------AAPDVIFQEDTSHTS 321
EE E EE++E + E + E E E E EE P Q +SH S
Sbjct: 300 EETIEVEEQQEGNDAEAQRREIELLRREGELPLEELLRSLPPQLLEGPSSPSQTPSSHDS 359
Query: 322 AQKAPELRGPESPSP-----KPEYSVIVEVRSD----DDKDEDTHSRKSTVTDESE 368
+ G E P KP S + + D+ DE+ + + DE +
Sbjct: 360 DTRDGPEEGAEEEPPQVLEIKPPPSAVTQRNKQPWHPDEDDEEFTANEEEAEDEED 415
Score = 37.4 bits (85), Expect = 0.080
Identities = 60/270 (22%), Positives = 97/270 (35%), Gaps = 43/270 (15%)
Query: 199 QEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLED---AASEESSKQKGIL 255
++ E A EE + L I+P + VT Q P ++ A EE+ ++ +
Sbjct: 362 RDGPEEGAEEEPPQVLEIKPPPSA----VTQRNKQPWHPDEDDEEFTANEEEAEDEEDTI 417
Query: 256 SHEEEDEEEEEEEEEEEEDEEEEE--------------------EEEEEEEEEEEEEEEE 295
+ EE+ E E + E E E E E+E+E+E + +
Sbjct: 418 AAEEQLEGEVDHAMELSELAREGELSMEELLQQYAGAYAPGSGSSEDEDEDEVDANSSDC 477
Query: 296 EEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDED 355
E E E EE QED+S S E + E + + + +E
Sbjct: 478 EPEGPVEAEEPP------QEDSSSQSDSVEDRSEDEEDEHSEEEETSGSSASEESESEES 531
Query: 356 THSRKSTVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEPGCPPAEQSQLGLGEPGK 415
++ + DE E D + G +E +A EQ G P + LG P K
Sbjct: 532 EDAQSQSQADEEEEDD-----DFG-VEYLLARDEEQSEADAGSGPPTPGPTTLG---PKK 582
Query: 416 AAKPLDTVRKSYYSKDPSRAEKREIKCPTP 445
+ +S K + A ++K P P
Sbjct: 583 EITDIAAAAESLQPKGYTLA-TTQVKTPIP 611
Score = 32.3 bits (72), Expect = 2.6
Identities = 35/159 (22%), Positives = 63/159 (39%), Gaps = 20/159 (12%)
Query: 196 HLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGIL 255
H+L++A A EE + AE+V E+ D P + A ++ + +
Sbjct: 2239 HILEQALCRAEDEEDIRAA--TQAKAEQVAELAEFNENDGFPAGEGEEAGRPGAEDEEMS 2296
Query: 256 SHEEEDE-----------------EEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEE 298
E+E E EE EE ++ EE+ E ++ ++ +EE
Sbjct: 2297 RAEQEIAALVEQLTPIERYAMKFLEASLEEVSREELKQAEEQVEAARKDLDQAKEEVFRL 2356
Query: 299 EEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPK 337
+EEEE A D T + +++ + + PE P +
Sbjct: 2357 PQEEEEGPGAGDE-SSCGTGGGTHRRSKKAKAPERPGTR 2394
Score = 30.8 bits (68), Expect = 7.5
Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 8/84 (9%)
Query: 685 SSSSCSSSPGVKSPDASQRHSSTSAPSSSMTSPQSSQASRQDEWDRPLDYTKPSRLREEE 744
+SS C V++ + Q SS S S + +DE + + S E E
Sbjct: 473 NSSDCEPEGPVEAEEPPQEDSS-----SQSDSVEDRSEDEEDEHSEEEETSGSSASEESE 527
Query: 745 PEESEPAAHSFASSEADDQEVSEE 768
EESE A + S+AD++E ++
Sbjct: 528 SEESEDAQ---SQSQADEEEEDDD 548
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 75.9 bits (185), Expect = 2e-13
Identities = 49/127 (38%), Positives = 65/127 (51%), Gaps = 21/127 (16%)
Query: 197 LLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTT---ERSQDLCPQSLEDAASEESSKQKG 253
L+ AA E EK +AE ++E + + Q++ S + K
Sbjct: 991 LISNAAVSEEEREAEK-------EAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKN 1043
Query: 254 ILSHEEED-----------EEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEE 302
H E E +E EEEEE+E+EEEEEEEEEEEE+EEEEEEEEEEEEE
Sbjct: 1044 KYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEE 1103
Query: 303 EEEEAAP 309
E +++P
Sbjct: 1104 ENIQSSP 1110
Score = 72.4 bits (176), Expect = 2e-12
Identities = 35/59 (59%), Positives = 42/59 (71%)
Query: 254 ILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVI 312
+L +E EEEEEEE+EEE+EEEEEEEE+EEEEEEEEEEEEEE + P +
Sbjct: 1061 LLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSV 1119
Score = 66.6 bits (161), Expect = 1e-10
Identities = 48/153 (31%), Positives = 72/153 (47%), Gaps = 17/153 (11%)
Query: 199 QEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHE 258
+E +EG S + E E ++ R ++ C + + E + I E
Sbjct: 1293 KETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEE 1352
Query: 259 EEDEEEEEEEEEEEEDEEEEE--------------EEEEEEE---EEEEEEEEEEEEEEE 301
EE+EEEEEEEEEEEE+ EEEE +E+EE E E+E+ ++ EEEE
Sbjct: 1353 EEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEE 1412
Query: 302 EEEEEAAPDVIFQEDTSHTSAQKAPELRGPESP 334
EE+EE + + D S ++ E+ E P
Sbjct: 1413 EEDEEPSHNEDHDADDEDDSHMESAEVEKEELP 1445
Score = 65.1 bits (157), Expect = 4e-10
Identities = 45/145 (31%), Positives = 71/145 (48%), Gaps = 11/145 (7%)
Query: 224 VVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEE--EEEEEEEEEDEEEEEEE 281
+ E E + L PQ E+ E + S E+ E++ + EEEEEEE+EEEEEEE
Sbjct: 1307 IEEEVKETGEALLPQE-ENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEE 1365
Query: 282 EEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYS 341
EEE EEEE E++ + + +E+ P++ +++ S E E PS ++
Sbjct: 1366 EEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDH- 1424
Query: 342 VIVEVRSDDDKDEDTHSRKSTVTDE 366
D D ++D+H + V E
Sbjct: 1425 -------DADDEDDSHMESAEVEKE 1442
Score = 55.5 bits (132), Expect = 3e-07
Identities = 31/111 (27%), Positives = 56/111 (50%), Gaps = 9/111 (8%)
Query: 216 IQPEDAEEVVEVTTERSQDLCPQSLE---------DAASEESSKQKGILSHEEEDEEEEE 266
I+PE+ EE E E ++ + E D A + ++ I + +E+ ++
Sbjct: 1348 IKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDD 1407
Query: 267 EEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDT 317
EEEEEEDEE E+ + ++E++ E E E+EE E+ +V+ ++T
Sbjct: 1408 HEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQET 1458
Score = 55.1 bits (131), Expect = 4e-07
Identities = 42/129 (32%), Positives = 62/129 (48%), Gaps = 29/129 (22%)
Query: 264 EEEEEEEEEEDEEEEEEEEE-----------------------EEEEEEEEEEEEEEEEE 300
EEE +E E +EE E EEEEEEEEEEEEEEEEE
Sbjct: 1308 EEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEE 1367
Query: 301 EEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDED-THSR 359
E EEEE +V ++D +Q+ E PE + K + + + + ++++DE+ +H+
Sbjct: 1368 EGEEEEGGGNV--EKDPDGAKSQEKEE---PEISTEKEDSARLDDHEEEEEEDEEPSHNE 1422
Query: 360 KSTVTDESE 368
DE +
Sbjct: 1423 DHDADDEDD 1431
Score = 52.8 bits (125), Expect = 2e-06
Identities = 55/224 (24%), Positives = 85/224 (37%), Gaps = 31/224 (13%)
Query: 176 EETL--VEEDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQ 233
EET V + KP ++ +E E EE E+ + E EE E+
Sbjct: 1327 EETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEE----EEEGEEEEGGGNVEKDP 1382
Query: 234 D--LCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEE 291
D + E S E + HEEE+EE+EE E+ D ++E++ E E E+E
Sbjct: 1383 DGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKE 1442
Query: 292 EEEEEEEEEEEEEEEAAPDVIFQE-------------DTSHTSAQKAPELRGPESPSPKP 338
E E +E E +E D+ Q D + + + EL G P P
Sbjct: 1443 ELPRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAG--DPEAVP 1500
Query: 339 EYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRGNLGLLE 382
E SD++ ++K + E+ GN +E
Sbjct: 1501 E--------SDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATME 1536
Score = 47.0 bits (110), Expect = 1e-04
Identities = 40/127 (31%), Positives = 50/127 (39%), Gaps = 57/127 (44%)
Query: 265 EEEEEEEEEDE---------EEEEEE---------------------------------- 281
EEE E E+E E E+EE+E
Sbjct: 999 EEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGER 1058
Query: 282 -----------EEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRG 330
EEEEEEE+EEEEEEEEEEEE+EEEE + +E+ P L
Sbjct: 1059 GQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEE---EEEEEENIQSSPPRLTK 1115
Query: 331 PESPSPK 337
P+S + K
Sbjct: 1116 PQSVAIK 1122
Score = 40.4 bits (93), Expect = 0.009
Identities = 45/184 (24%), Positives = 68/184 (36%), Gaps = 52/184 (28%)
Query: 228 TTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEE 287
T R+ +L P SL ++S+ EEE E E+E E E+ E+EE+E
Sbjct: 973 TCSRANELDPDSLRWTPI--------LISNAAVSEEEREAEKEAERLMEQASCWEKEEQE 1024
Query: 288 -----------------------------------------EEEEEEEEEEEEEEEEEEE 306
+E EEEEEEE+EEEEEEE
Sbjct: 1025 ILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEE 1084
Query: 307 AAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRK---STV 363
+ +E+ ++ ++ KP+ I R K + R+ S+V
Sbjct: 1085 EEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSV 1144
Query: 364 TDES 367
T E+
Sbjct: 1145 TTET 1148
>gi|21361639 DIPB protein [Homo sapiens]
Length = 344
Score = 75.5 bits (184), Expect = 3e-13
Identities = 41/114 (35%), Positives = 66/114 (57%), Gaps = 6/114 (5%)
Query: 218 PEDAE----EVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEE 273
P D E E EV E+ +++ ++ E++ SEE S+ + EEE E+E +EE EE+
Sbjct: 70 PADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDS 129
Query: 274 DEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPE 327
+EE E+E+E E EE+ +EE E E E E E E E P++ + + + +K P+
Sbjct: 130 EEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEI--EMEAERVAKRKCPD 181
Score = 67.4 bits (163), Expect = 7e-11
Identities = 41/119 (34%), Positives = 61/119 (51%), Gaps = 1/119 (0%)
Query: 232 SQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEE 291
SQ P + + A +E ++ K E E E EE E EEE + EEE E EEE E+E +E
Sbjct: 64 SQAWTPPADGEGAGKEEAEVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDE 123
Query: 292 EEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDD 350
E EE+ EEE E+E+E+ + QE+ + A+ E P + E + + + D
Sbjct: 124 ESEEDSEEEMEDEQESEAEEDNQEE-GESEAEGETEAESEFDPEIEMEAERVAKRKCPD 181
Score = 61.2 bits (147), Expect = 5e-09
Identities = 38/106 (35%), Positives = 50/106 (47%), Gaps = 4/106 (3%)
Query: 203 EGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDE 262
EGA EE E ++ E E+ E S+ E+ + E + EED
Sbjct: 74 EGAGKEEAE----VKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDS 129
Query: 263 EEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAA 308
EEE E+E+E E EE+ +EE E E E E E E E + E E E E A
Sbjct: 130 EEEMEDEQESEAEEDNQEEGESEAEGETEAESEFDPEIEMEAERVA 175
Score = 48.9 bits (115), Expect = 3e-05
Identities = 40/145 (27%), Positives = 56/145 (38%), Gaps = 6/145 (4%)
Query: 217 QPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEE------DEEEEEEEEE 270
+P++A EV E C + E + S H + D E +EE
Sbjct: 22 EPDEAPGAEEVCRECGFCYCRRHAEAHRQKFLSHHLAEYVHGSQAWTPPADGEGAGKEEA 81
Query: 271 EEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRG 330
E + E+E E E E EE E EEE E EEE E EEE E+ S + E
Sbjct: 82 EVKVEQEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEA 141
Query: 331 PESPSPKPEYSVIVEVRSDDDKDED 355
E + E E ++ + D +
Sbjct: 142 EEDNQEEGESEAEGETEAESEFDPE 166
Score = 46.2 bits (108), Expect = 2e-04
Identities = 36/110 (32%), Positives = 53/110 (48%), Gaps = 9/110 (8%)
Query: 207 SEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEE 266
SE GE+ + ++EE E T E S+D D SEE S+++ +E++ E EE
Sbjct: 93 SEAGEESESEEESESEEESE-TEEESEDE-----SDEESEEDSEEE---MEDEQESEAEE 143
Query: 267 EEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQED 316
+ +EE E E E E E E E + E E E E + + + QED
Sbjct: 144 DNQEEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQED 193
Score = 30.8 bits (68), Expect = 7.5
Identities = 51/264 (19%), Positives = 93/264 (35%), Gaps = 30/264 (11%)
Query: 58 KKRKLEGAEAEHLVSKRKSHPLKLALDEGYGVDSDGSEDTEVKDASVSDESEGTLEG--- 114
++R++E E S+ +S + + E D E E + + DE E E
Sbjct: 87 QEREIESEAGEESESEEESESEEESETEEESEDESDEESEEDSEEEMEDEQESEAEEDNQ 146
Query: 115 ------AEAETSGQDEIHRPETAEGRSPVKSHFGSNPIGSATASSK------------GS 156
AE ET + E E K + + +T + G+
Sbjct: 147 EEGESEAEGETEAESEFDPEIEMEAERVAKRKCPDHGLDLSTYCQEDRQLICVLCPVIGA 206
Query: 157 YSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFI 216
+ +Q L L + EE L +D G +V L+ + + +FI
Sbjct: 207 HQGHQ------LSTLDEAFEE-LRSKDSGGLKAAMIELVERLKFKSSDPKVTRDQMKMFI 259
Query: 217 QPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQ--KGILSHEEEDEEEEEEEEEEEED 274
Q E + + E + L +++A + + I SH + + + +E+ +
Sbjct: 260 QQEFKKVQKVIADEEQKALHLVDIQEAMATAHVTEILADIQSHMDRLMTQMAQAKEQLDT 319
Query: 275 EEEEEEEEEEEEEEEEEEEEEEEE 298
E E + E +EE EEE+
Sbjct: 320 SNESAEPKAEGDEEGPSGASEEED 343
>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
Length = 740
Score = 75.1 bits (183), Expect = 3e-13
Identities = 44/108 (40%), Positives = 63/108 (58%), Gaps = 12/108 (11%)
Query: 207 SEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILS------HEEE 260
SEEGE+ + ++ T+ S D SL+ +G S +E+
Sbjct: 386 SEEGER------KKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDED 439
Query: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAA 308
DEE +EEEEEEEE+EEEE + EEEE+ E+ +E +E++EEE+EEEEAA
Sbjct: 440 DEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAA 487
Score = 40.0 bits (92), Expect = 0.012
Identities = 38/166 (22%), Positives = 72/166 (43%), Gaps = 12/166 (7%)
Query: 207 SEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEED-EEEE 265
S EG G+ Q + E E ++ E+ EE +++ S EEED E+ +
Sbjct: 415 SGEGPSGMASQGCPSASRAETDDEDDEE---SDEEEEEEEEEEEEEATDSEEEEDLEQMQ 471
Query: 266 EEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKA 325
E +E++EE++EEEE ++ ++ + E+ E + Q S Q
Sbjct: 472 EGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGK-------QISRSSGEQQNK 524
Query: 326 PELRGPESPSPKPEYSVIVEVRSDDDKDED-THSRKSTVTDESEMQ 370
+ P S +P ++ S+ ++ E+ T +S V+ E++
Sbjct: 525 GRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELE 570
Score = 39.7 bits (91), Expect = 0.016
Identities = 31/138 (22%), Positives = 56/138 (40%), Gaps = 24/138 (17%)
Query: 240 LEDAASEESSKQK-----GILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEE 294
L+D + E K++ G SH + E + E + E ++E++E
Sbjct: 382 LQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDE 441
Query: 295 EEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDE 354
E +EEEEEEEEE E+ T +++ +L + D+++DE
Sbjct: 442 ESDEEEEEEEEE--------EEEEATDSEEEEDLEQMQEGQ-----------EDDEEEDE 482
Query: 355 DTHSRKSTVTDESEMQDM 372
+ + D+S M +
Sbjct: 483 EEEAAAGKDGDKSPMSSL 500
Score = 35.8 bits (81), Expect = 0.23
Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 10/103 (9%)
Query: 670 DLSMHKHRKRENAFPSSSSCSSSPGVKSPDASQRHSSTSAPSSSMTSPQSSQASRQDEWD 729
D S RK+ A +S S+ +P+AS + +S P +S+A DE D
Sbjct: 384 DKSEEGERKKRRARLQGTSSHSAD---TPEASLDSGEGPSGMASQGCPSASRAETDDEDD 440
Query: 730 RPLDYTKPSRLREEEPEESEPAAHSFASSEADDQEVSEENFEE 772
D EEE EE E + S E +D E +E E+
Sbjct: 441 EESD-------EEEEEEEEEEEEEATDSEEEEDLEQMQEGQED 476
>gi|215422388 death-domain associated protein isoform a [Homo
sapiens]
Length = 740
Score = 75.1 bits (183), Expect = 3e-13
Identities = 44/108 (40%), Positives = 63/108 (58%), Gaps = 12/108 (11%)
Query: 207 SEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILS------HEEE 260
SEEGE+ + ++ T+ S D SL+ +G S +E+
Sbjct: 386 SEEGER------KKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDED 439
Query: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAA 308
DEE +EEEEEEEE+EEEE + EEEE+ E+ +E +E++EEE+EEEEAA
Sbjct: 440 DEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAA 487
Score = 40.0 bits (92), Expect = 0.012
Identities = 38/166 (22%), Positives = 72/166 (43%), Gaps = 12/166 (7%)
Query: 207 SEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEED-EEEE 265
S EG G+ Q + E E ++ E+ EE +++ S EEED E+ +
Sbjct: 415 SGEGPSGMASQGCPSASRAETDDEDDEE---SDEEEEEEEEEEEEEATDSEEEEDLEQMQ 471
Query: 266 EEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKA 325
E +E++EE++EEEE ++ ++ + E+ E + Q S Q
Sbjct: 472 EGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGK-------QISRSSGEQQNK 524
Query: 326 PELRGPESPSPKPEYSVIVEVRSDDDKDED-THSRKSTVTDESEMQ 370
+ P S +P ++ S+ ++ E+ T +S V+ E++
Sbjct: 525 GRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELE 570
Score = 39.7 bits (91), Expect = 0.016
Identities = 31/138 (22%), Positives = 56/138 (40%), Gaps = 24/138 (17%)
Query: 240 LEDAASEESSKQK-----GILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEE 294
L+D + E K++ G SH + E + E + E ++E++E
Sbjct: 382 LQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDE 441
Query: 295 EEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDE 354
E +EEEEEEEEE E+ T +++ +L + D+++DE
Sbjct: 442 ESDEEEEEEEEE--------EEEEATDSEEEEDLEQMQEGQ-----------EDDEEEDE 482
Query: 355 DTHSRKSTVTDESEMQDM 372
+ + D+S M +
Sbjct: 483 EEEAAAGKDGDKSPMSSL 500
Score = 35.8 bits (81), Expect = 0.23
Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 10/103 (9%)
Query: 670 DLSMHKHRKRENAFPSSSSCSSSPGVKSPDASQRHSSTSAPSSSMTSPQSSQASRQDEWD 729
D S RK+ A +S S+ +P+AS + +S P +S+A DE D
Sbjct: 384 DKSEEGERKKRRARLQGTSSHSAD---TPEASLDSGEGPSGMASQGCPSASRAETDDEDD 440
Query: 730 RPLDYTKPSRLREEEPEESEPAAHSFASSEADDQEVSEENFEE 772
D EEE EE E + S E +D E +E E+
Sbjct: 441 EESD-------EEEEEEEEEEEEEATDSEEEEDLEQMQEGQED 476
>gi|215422366 death-domain associated protein isoform b [Homo
sapiens]
Length = 752
Score = 75.1 bits (183), Expect = 3e-13
Identities = 44/108 (40%), Positives = 63/108 (58%), Gaps = 12/108 (11%)
Query: 207 SEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILS------HEEE 260
SEEGE+ + ++ T+ S D SL+ +G S +E+
Sbjct: 398 SEEGER------KKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDED 451
Query: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAA 308
DEE +EEEEEEEE+EEEE + EEEE+ E+ +E +E++EEE+EEEEAA
Sbjct: 452 DEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAA 499
Score = 40.0 bits (92), Expect = 0.012
Identities = 38/166 (22%), Positives = 72/166 (43%), Gaps = 12/166 (7%)
Query: 207 SEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEED-EEEE 265
S EG G+ Q + E E ++ E+ EE +++ S EEED E+ +
Sbjct: 427 SGEGPSGMASQGCPSASRAETDDEDDEE---SDEEEEEEEEEEEEEATDSEEEEDLEQMQ 483
Query: 266 EEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKA 325
E +E++EE++EEEE ++ ++ + E+ E + Q S Q
Sbjct: 484 EGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGK-------QISRSSGEQQNK 536
Query: 326 PELRGPESPSPKPEYSVIVEVRSDDDKDED-THSRKSTVTDESEMQ 370
+ P S +P ++ S+ ++ E+ T +S V+ E++
Sbjct: 537 GRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELE 582
Score = 39.7 bits (91), Expect = 0.016
Identities = 31/138 (22%), Positives = 56/138 (40%), Gaps = 24/138 (17%)
Query: 240 LEDAASEESSKQK-----GILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEE 294
L+D + E K++ G SH + E + E + E ++E++E
Sbjct: 394 LQDKSEEGERKKRRARLQGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDE 453
Query: 295 EEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDE 354
E +EEEEEEEEE E+ T +++ +L + D+++DE
Sbjct: 454 ESDEEEEEEEEE--------EEEEATDSEEEEDLEQMQEGQ-----------EDDEEEDE 494
Query: 355 DTHSRKSTVTDESEMQDM 372
+ + D+S M +
Sbjct: 495 EEEAAAGKDGDKSPMSSL 512
Score = 35.8 bits (81), Expect = 0.23
Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 10/103 (9%)
Query: 670 DLSMHKHRKRENAFPSSSSCSSSPGVKSPDASQRHSSTSAPSSSMTSPQSSQASRQDEWD 729
D S RK+ A +S S+ +P+AS + +S P +S+A DE D
Sbjct: 396 DKSEEGERKKRRARLQGTSSHSAD---TPEASLDSGEGPSGMASQGCPSASRAETDDEDD 452
Query: 730 RPLDYTKPSRLREEEPEESEPAAHSFASSEADDQEVSEENFEE 772
D EEE EE E + S E +D E +E E+
Sbjct: 453 EESD-------EEEEEEEEEEEEEATDSEEEEDLEQMQEGQED 488
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.125 0.353
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,095,670
Number of Sequences: 37866
Number of extensions: 2961495
Number of successful extensions: 177715
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1932
Number of HSP's successfully gapped in prelim test: 735
Number of HSP's that attempted gapping in prelim test: 35193
Number of HSP's gapped (non-prelim): 39866
length of query: 1121
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1008
effective length of database: 13,968,660
effective search space: 14080409280
effective search space used: 14080409280
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.