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Search of human proteins with 17402886
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|17402886 HEAT-like repeat-containing protein isoform 1 [Homo
sapiens]
(873 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|17402886 HEAT-like repeat-containing protein isoform 1 [Homo ... 1721 0.0
gi|17402884 HEAT-like repeat-containing protein isoform 2 [Homo ... 194 2e-49
gi|21361399 alpha isoform of regulatory subunit A, protein phosp... 71 5e-12
gi|32455246 beta isoform of regulatory subunit A, protein phosph... 65 2e-10
gi|32455244 beta isoform of regulatory subunit A, protein phosph... 65 2e-10
gi|4826934 protein phosphatase 4, regulatory subunit 1 isoform b... 47 6e-05
gi|108936953 protein phosphatase 4, regulatory subunit 1 isoform... 47 6e-05
gi|150456424 RW1 protein [Homo sapiens] 43 0.001
gi|239755778 PREDICTED: mucin 19, oligomeric [Homo sapiens] 40 0.007
gi|239750280 PREDICTED: mucin 19, oligomeric [Homo sapiens] 40 0.007
gi|239744589 PREDICTED: mucin 19 [Homo sapiens] 40 0.007
gi|122937227 U2-associated SR140 protein [Homo sapiens] 40 0.009
gi|33457330 tetratricopeptide repeat domain 14 isoform a [Homo s... 39 0.016
gi|219842214 protein phosphatase 1, regulatory (inhibitor) subun... 38 0.036
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun... 38 0.036
gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit... 38 0.036
gi|28376658 hypothetical protein LOC285172 [Homo sapiens] 38 0.036
gi|40805104 topoisomerase I binding, arginine/serine-rich [Homo ... 37 0.080
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] 37 0.080
gi|189011568 adenomatous polyposis coli [Homo sapiens] 37 0.10
gi|189011566 adenomatous polyposis coli [Homo sapiens] 37 0.10
gi|53759122 adenomatous polyposis coli [Homo sapiens] 37 0.10
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 36 0.14
gi|47578107 delangin isoform B [Homo sapiens] 36 0.14
gi|47578105 delangin isoform A [Homo sapiens] 36 0.14
gi|115430243 SCY1-like 1 isoform B [Homo sapiens] 36 0.18
gi|115430241 SCY1-like 1 isoform A [Homo sapiens] 36 0.18
gi|164419758 bromodomain containing 2 [Homo sapiens] 36 0.18
gi|4826806 bromodomain containing 2 [Homo sapiens] 36 0.18
gi|11067749 bromodomain containing protein 3 [Homo sapiens] 36 0.18
>gi|17402886 HEAT-like repeat-containing protein isoform 1 [Homo
sapiens]
Length = 873
Score = 1721 bits (4458), Expect = 0.0
Identities = 873/873 (100%), Positives = 873/873 (100%)
Query: 1 MHPPPPAAAMDFSQNSLFGYMEDLQELTIIERPVRRSLKTPEEIERLTVDEDLSDIERAV 60
MHPPPPAAAMDFSQNSLFGYMEDLQELTIIERPVRRSLKTPEEIERLTVDEDLSDIERAV
Sbjct: 1 MHPPPPAAAMDFSQNSLFGYMEDLQELTIIERPVRRSLKTPEEIERLTVDEDLSDIERAV 60
Query: 61 YLLSAGQDVQGTSVIANLPFLMRQNPTETLRRVLPKVREALHVAGVEMQLTAAMSFLTIL 120
YLLSAGQDVQGTSVIANLPFLMRQNPTETLRRVLPKVREALHVAGVEMQLTAAMSFLTIL
Sbjct: 61 YLLSAGQDVQGTSVIANLPFLMRQNPTETLRRVLPKVREALHVAGVEMQLTAAMSFLTIL 120
Query: 121 QDESVSIHAYTHSFLQVILLHLEHRDTGVSNAWLETLLSVIEVLPKETLRHEILNPLVSK 180
QDESVSIHAYTHSFLQVILLHLEHRDTGVSNAWLETLLSVIEVLPKETLRHEILNPLVSK
Sbjct: 121 QDESVSIHAYTHSFLQVILLHLEHRDTGVSNAWLETLLSVIEVLPKETLRHEILNPLVSK 180
Query: 181 AQLSQTVQSRLVSCKILGKLTNKFDAHTIKREILPLVKSLCQDVEYEVRSCMCRQLENIA 240
AQLSQTVQSRLVSCKILGKLTNKFDAHTIKREILPLVKSLCQDVEYEVRSCMCRQLENIA
Sbjct: 181 AQLSQTVQSRLVSCKILGKLTNKFDAHTIKREILPLVKSLCQDVEYEVRSCMCRQLENIA 240
Query: 241 QGIGTELTKSVVLPELIELSRDEGSSVRLAAFETLVNLLDIFDTDDRSQTILPLVKSFCE 300
QGIGTELTKSVVLPELIELSRDEGSSVRLAAFETLVNLLDIFDTDDRSQTILPLVKSFCE
Sbjct: 241 QGIGTELTKSVVLPELIELSRDEGSSVRLAAFETLVNLLDIFDTDDRSQTILPLVKSFCE 300
Query: 301 KSFKADESILISLSFHLGKLCHGLYGIFTPDQHLRFLEFYKKLCTLGLQQENGHNENQIP 360
KSFKADESILISLSFHLGKLCHGLYGIFTPDQHLRFLEFYKKLCTLGLQQENGHNENQIP
Sbjct: 301 KSFKADESILISLSFHLGKLCHGLYGIFTPDQHLRFLEFYKKLCTLGLQQENGHNENQIP 360
Query: 361 PQILEQEKKYISVRKNCAYNFPAMIVFVDPKNFHMELYSTFFCLCHDPEVPVRYTIAICF 420
PQILEQEKKYISVRKNCAYNFPAMIVFVDPKNFHMELYSTFFCLCHDPEVPVRYTIAICF
Sbjct: 361 PQILEQEKKYISVRKNCAYNFPAMIVFVDPKNFHMELYSTFFCLCHDPEVPVRYTIAICF 420
Query: 421 YEVSKLLNSGVYLIHKELITLLQDESLEVLDALIDHLPEILELMSTGGESSVQENKLSSL 480
YEVSKLLNSGVYLIHKELITLLQDESLEVLDALIDHLPEILELMSTGGESSVQENKLSSL
Sbjct: 421 YEVSKLLNSGVYLIHKELITLLQDESLEVLDALIDHLPEILELMSTGGESSVQENKLSSL 480
Query: 481 PDLIPALTAAEQRAAASLKWRTHEKLLQKYACLPHVISSDQIYYRFLQRMFTIMMTNNVL 540
PDLIPALTAAEQRAAASLKWRTHEKLLQKYACLPHVISSDQIYYRFLQRMFTIMMTNNVL
Sbjct: 481 PDLIPALTAAEQRAAASLKWRTHEKLLQKYACLPHVISSDQIYYRFLQRMFTIMMTNNVL 540
Query: 541 PVQKAASRTLCIFLRYNRKQEQRHEVIQKLIEQLGQGKSYWNRLRFLDTCEFIIEIFSKS 600
PVQKAASRTLCIFLRYNRKQEQRHEVIQKLIEQLGQGKSYWNRLRFLDTCEFIIEIFSKS
Sbjct: 541 PVQKAASRTLCIFLRYNRKQEQRHEVIQKLIEQLGQGKSYWNRLRFLDTCEFIIEIFSKS 600
Query: 601 FFCKYFFLPAIELTHDPVANVRMKLCYLLPKVKSTLKIPADKHLLQQLEMCVRKLLCQEK 660
FFCKYFFLPAIELTHDPVANVRMKLCYLLPKVKSTLKIPADKHLLQQLEMCVRKLLCQEK
Sbjct: 601 FFCKYFFLPAIELTHDPVANVRMKLCYLLPKVKSTLKIPADKHLLQQLEMCVRKLLCQEK 660
Query: 661 DKDVLAIVKRTVLELDRMEMSMDAFQKKFYEKDLLDQEKEREELLLLEMEQLEKEKQQND 720
DKDVLAIVKRTVLELDRMEMSMDAFQKKFYEKDLLDQEKEREELLLLEMEQLEKEKQQND
Sbjct: 661 DKDVLAIVKRTVLELDRMEMSMDAFQKKFYEKDLLDQEKEREELLLLEMEQLEKEKQQND 720
Query: 721 GRPMSDKMFEKKRRDTKTPTQSLPKNIPISVPGPSSVTPSTSKEIKKSKLIRSQSFNNQA 780
GRPMSDKMFEKKRRDTKTPTQSLPKNIPISVPGPSSVTPSTSKEIKKSKLIRSQSFNNQA
Sbjct: 721 GRPMSDKMFEKKRRDTKTPTQSLPKNIPISVPGPSSVTPSTSKEIKKSKLIRSQSFNNQA 780
Query: 781 FHAKYGNLEKCASKSSTTGYTTSVSGLGKTSVLSLADDSFRTRNASSVPSSFSPNTPLPS 840
FHAKYGNLEKCASKSSTTGYTTSVSGLGKTSVLSLADDSFRTRNASSVPSSFSPNTPLPS
Sbjct: 781 FHAKYGNLEKCASKSSTTGYTTSVSGLGKTSVLSLADDSFRTRNASSVPSSFSPNTPLPS 840
Query: 841 TSRGTGNSVDPKSSGSKDTQPRKATLKSRKSNP 873
TSRGTGNSVDPKSSGSKDTQPRKATLKSRKSNP
Sbjct: 841 TSRGTGNSVDPKSSGSKDTQPRKATLKSRKSNP 873
>gi|17402884 HEAT-like repeat-containing protein isoform 2 [Homo
sapiens]
Length = 120
Score = 194 bits (494), Expect = 2e-49
Identities = 98/98 (100%), Positives = 98/98 (100%)
Query: 1 MHPPPPAAAMDFSQNSLFGYMEDLQELTIIERPVRRSLKTPEEIERLTVDEDLSDIERAV 60
MHPPPPAAAMDFSQNSLFGYMEDLQELTIIERPVRRSLKTPEEIERLTVDEDLSDIERAV
Sbjct: 1 MHPPPPAAAMDFSQNSLFGYMEDLQELTIIERPVRRSLKTPEEIERLTVDEDLSDIERAV 60
Query: 61 YLLSAGQDVQGTSVIANLPFLMRQNPTETLRRVLPKVR 98
YLLSAGQDVQGTSVIANLPFLMRQNPTETLRRVLPKVR
Sbjct: 61 YLLSAGQDVQGTSVIANLPFLMRQNPTETLRRVLPKVR 98
>gi|21361399 alpha isoform of regulatory subunit A, protein
phosphatase 2 [Homo sapiens]
Length = 589
Score = 70.9 bits (172), Expect = 5e-12
Identities = 110/552 (19%), Positives = 213/552 (38%), Gaps = 54/552 (9%)
Query: 130 YTHSFLQVILLHLEHRDTGVSNAWLETLLSVI-EVLPKETLRHEILNPLVSKAQLSQTVQ 188
Y H L + +T V + +E+L ++ E P + H + PLV +
Sbjct: 85 YVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFV--PLVKRLAGGDWFT 142
Query: 189 SRLVSCKILGKLTNKFDAHTIKREILPLVKSLCQDVEYEVRSCMCRQLENIAQGIGTELT 248
SR +C + + + +K E+ ++LC D VR +L A+ + +
Sbjct: 143 SRTSACGLFSVCYPRVSS-AVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDNV 201
Query: 249 KSVVLPELIELSRDEGSSVRLAAFETLVNLLDIFDTDDRSQTILPLVKSFCE-KSFKADE 307
KS ++P L+ DE SVRL A E VN+ + +D ++P ++ E KS++
Sbjct: 202 KSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWR--- 258
Query: 308 SILISLSFHLGKLCHGLYGIFTPDQHLRFLEFYKKLCTLGLQQENGHNENQIPPQILEQE 367
+ ++ +L + T + + K C ++ H + +
Sbjct: 259 -VRYMVADKFTELQKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADC 317
Query: 368 KKYISVRKNCAYNFPAMIVFVDPKNFHMELYSTFFCLCHDPEVPVRYTIAICFYEVSKLL 427
++ + + + P + V N H V+ +A +S +L
Sbjct: 318 RENVIM----SQILPCIKELVSDANQH-----------------VKSALASVIMGLSPIL 356
Query: 428 NSGVYLIH--KELITLLQDESLEVLDALIDHLPEILELMSTGGESSVQENKLSSLPDLIP 485
+ H + L+DE EV +I +L + E++ +++ S LP ++
Sbjct: 357 GKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVI------GIRQLSQSLLPAIV- 409
Query: 486 ALTAAEQRAAASLKWRTHEKLLQKYACLPHVISSDQIYYRFLQRMFTIMMTNNVLPVQKA 545
A KWR +++ L + + + L + + ++V +++A
Sbjct: 410 -------ELAEDAKWRVRLAIIEYMPLLAGQLGV-EFFDEKLNSLCMAWLVDHVYAIREA 461
Query: 546 ASRTLCIFLRYNRKQEQRHEVIQKLIEQLGQGKSYWNRLRFLDTCEFIIEIFSKSFFCKY 605
A+ L + K+ +I K++ G +Y +R+ L + E+ + K+
Sbjct: 462 ATSNLKKLVEKFGKEWAHATIIPKVLAMSGD-PNYLHRMTTLFCINVLSEVCGQDITTKH 520
Query: 606 FFLPAIELTHDPVANVRMKLCYLLPKVKSTLKIPADKHLLQQLEMCVRKLLCQEKDKDVL 665
+ + DPVANVR + L K+ L D LQ + + L Q++D DV
Sbjct: 521 MLPTVLRMAGDPVANVRFNVAKSLQKIGPIL----DNSTLQSEVKPILEKLTQDQDVDVK 576
Query: 666 AIVKR--TVLEL 675
+ TVL L
Sbjct: 577 YFAQEALTVLSL 588
Score = 39.7 bits (91), Expect = 0.012
Identities = 51/229 (22%), Positives = 91/229 (39%), Gaps = 7/229 (3%)
Query: 73 SVIANL-PFLMRQNPTETLRRVLPKVREALHVAGVEMQLTAAMSFLTILQDESVSIHAYT 131
SVI L P L + N T+ +LP L E++L + + +E + I +
Sbjct: 347 SVIMGLSPILGKDN---TIEHLLPLFLAQLKDECPEVRLNIISNLDCV--NEVIGIRQLS 401
Query: 132 HSFLQVILLHLEHRDTGVSNAWLETLLSVIEVLPKETLRHEILNPLVSKAQLSQTVQSRL 191
S L I+ E V A +E + + L E E LN L + R
Sbjct: 402 QSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFF-DEKLNSLCMAWLVDHVYAIRE 460
Query: 192 VSCKILGKLTNKFDAHTIKREILPLVKSLCQDVEYEVRSCMCRQLENIAQGIGTELTKSV 251
+ L KL KF I+P V ++ D Y R + +++ G ++T
Sbjct: 461 AATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKH 520
Query: 252 VLPELIELSRDEGSSVRLAAFETLVNLLDIFDTDDRSQTILPLVKSFCE 300
+LP ++ ++ D ++VR ++L + I D + P+++ +
Sbjct: 521 MLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQ 569
Score = 30.0 bits (66), Expect = 9.8
Identities = 25/90 (27%), Positives = 44/90 (48%), Gaps = 5/90 (5%)
Query: 222 QDVEYEVRSCMCRQLENIAQGIGTELTKSVVLPELIELSRDEGSSVRLAAFETLVNLLDI 281
+DV+ + S ++L IA +G E T+S +LP L + DE V LA E L +
Sbjct: 23 EDVQLRLNSI--KKLSTIALALGVERTRSELLPFLTDTIYDE-DEVLLALAEQLGTFTTL 79
Query: 282 FDTDDRSQTILPLVKSFC--EKSFKADESI 309
+ +LP ++S E++ D+++
Sbjct: 80 VGGPEYVHCLLPPLESLATVEETVVRDKAV 109
>gi|32455246 beta isoform of regulatory subunit A, protein
phosphatase 2 isoform a [Homo sapiens]
Length = 601
Score = 65.5 bits (158), Expect = 2e-10
Identities = 96/492 (19%), Positives = 195/492 (39%), Gaps = 49/492 (9%)
Query: 176 PLVSKAQLSQTVQSRLVSCKILGKLTNKFDAHTIKREILPLVKSLCQDVEYEVRSCMCRQ 235
PLV + SR +C + + ++ +K EI +SLC D VR +
Sbjct: 142 PLVKRLASGDWFTSRTSACGLFSVCYPRA-SNAVKAEIRQQFRSLCSDDTPMVRRAAASK 200
Query: 236 LENIAQGIGTELTKSVVLPELIELSRDEGSSVRLAAFETLVNLLDIFDTDDRSQTILPLV 295
L A+ + + KS ++P L+ DE SVRL A E V++ + DD ++P +
Sbjct: 201 LGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTL 260
Query: 296 KSFCE-KSFKADESILISLSFHLGKLCHGLYGIFTPDQHLRFLEFYKKLCTLGLQQENGH 354
+ E KS++ + ++ +L + T + + + K C ++ H
Sbjct: 261 RQAAEDKSWR----VRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAAAH 316
Query: 355 NENQIPPQILEQEKKYISVRKNCAYNFPAMIVFVDPKNFHMELYSTFFCLCHDPEVPVRY 414
++ + ++++ I + + Y EL S D V+
Sbjct: 317 KVKELGENLPIEDRETIIMNQILPY--------------IKELVS-------DTNQHVKS 355
Query: 415 TIAICFYEVSKLLNSGVYLIH--KELITLLQDESLEVLDALIDHLPEILELMSTGGESSV 472
+A +S +L + H + L+DE +V +I +L + E++ +
Sbjct: 356 ALASVIMGLSTILGKENTIEHLLPLFLAQLKDECPDVRLNIISNLDCVNEVI------GI 409
Query: 473 QENKLSSLPDLIPALTAAEQRAAASLKWRTHEKLLQKYACLPHVISSDQIYYRFLQRMFT 532
++ S LP ++ A KWR +++ L + + + L +
Sbjct: 410 RQLSQSLLPAIV--------ELAEDAKWRVRLAIIEYMPLLAGQLGV-EFFDEKLNSLCM 460
Query: 533 IMMTNNVLPVQKAASRTLCIFLRYNRKQEQRHEVIQKLIEQLGQGKSYWNRLRFLDTCEF 592
+ ++V +++AA+ L ++ + ++ ++ K++ + +Y +R+ L
Sbjct: 461 AWLVDHVYAIREAATNNLMKLVQKFGTEWAQNTIVPKVL-VMANDPNYLHRMTTLFCINA 519
Query: 593 IIEIFSKSFFCKYFFLPAIELTHDPVANVRMKLCYLLPKVKSTLKIPADKHLLQQLEMCV 652
+ E + K +++ D VANVR + L K+ L D + LQ V
Sbjct: 520 LSEACGQEITTKQMLPIVLKMAGDQVANVRFNVAKSLQKIGPIL----DTNALQGEVKPV 575
Query: 653 RKLLCQEKDKDV 664
+ L Q++D DV
Sbjct: 576 LQKLGQDEDMDV 587
Score = 42.7 bits (99), Expect = 0.001
Identities = 40/175 (22%), Positives = 74/175 (42%), Gaps = 1/175 (0%)
Query: 122 DESVSIHAYTHSFLQVILLHLEHRDTGVSNAWLETLLSVIEVLPKETLRHEILNPLVSKA 181
+E + I + S L I+ E V A +E + + L E E LN L
Sbjct: 404 NEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFF-DEKLNSLCMAW 462
Query: 182 QLSQTVQSRLVSCKILGKLTNKFDAHTIKREILPLVKSLCQDVEYEVRSCMCRQLENIAQ 241
+ R + L KL KF + I+P V + D Y R + +++
Sbjct: 463 LVDHVYAIREAATNNLMKLVQKFGTEWAQNTIVPKVLVMANDPNYLHRMTTLFCINALSE 522
Query: 242 GIGTELTKSVVLPELIELSRDEGSSVRLAAFETLVNLLDIFDTDDRSQTILPLVK 296
G E+T +LP +++++ D+ ++VR ++L + I DT+ + P+++
Sbjct: 523 ACGQEITTKQMLPIVLKMAGDQVANVRFNVAKSLQKIGPILDTNALQGEVKPVLQ 577
Score = 37.7 bits (86), Expect = 0.047
Identities = 49/197 (24%), Positives = 90/197 (45%), Gaps = 9/197 (4%)
Query: 81 LMRQNPTETLRRVLPKVREALHVAGVEMQLTAAMSF--LTILQDESVSIHAYTHSFLQVI 138
L+ Q+ ETL V+P +R+A ++ A F L ++++ +F Q +
Sbjct: 246 LLSQDDLETL--VMPTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAF-QNL 302
Query: 139 LLHLEHRDTGVSNAWLETLLSVIEVLPKETLRHEILNPLVSK--AQLSQTVQSRLVSCKI 196
L E + ++ L + + +ET+ + P + + + +Q V+S L S I
Sbjct: 303 LKDCEAEVRAAAAHKVKELGENLPIEDRETIIMNQILPYIKELVSDTNQHVKSALASV-I 361
Query: 197 LGKLTNKFDAHTIKREILPLVKSLCQDVEYEVRSCMCRQLENIAQGIGTELTKSVVLPEL 256
+G T +TI+ +LPL + +D +VR + L+ + + IG +LP +
Sbjct: 362 MGLSTILGKENTIEH-LLPLFLAQLKDECPDVRLNIISNLDCVNEVIGIRQLSQSLLPAI 420
Query: 257 IELSRDEGSSVRLAAFE 273
+EL+ D VRLA E
Sbjct: 421 VELAEDAKWRVRLAIIE 437
Score = 34.3 bits (77), Expect = 0.52
Identities = 68/296 (22%), Positives = 115/296 (38%), Gaps = 31/296 (10%)
Query: 222 QDVEYEVRSCMCRQLENIAQGIGTELTKSVVLPELIELSRDEGSSVRLAAFETLVNLLDI 281
+DV+ + S ++L IA +G E T+S +LP L + DE V LA E L N +
Sbjct: 35 EDVQLRLNSI--KKLSTIALALGVERTRSELLPFLTDTIYDE-DEVLLALAEQLGNFTGL 91
Query: 282 FDTDDRSQTILPLVKSFC--EKSFKADESI--LISLSFHLGKLCHGLYGIFTPDQHLRFL 337
D + +LP +++ E++ D+++ L +S + Y + +
Sbjct: 92 VGGPDFAHCLLPPLENLATVEETVVRDKAVESLRQISQEHTPVALEAYFVPLVKRLASGD 151
Query: 338 EFYKKLCTLGLQQE-NGHNENQIPPQILEQEKKYIS-----VRKNCAYNFPAMIVFVDPK 391
F + GL N + +I +Q + S VR+ A ++
Sbjct: 152 WFTSRTSACGLFSVCYPRASNAVKAEIRQQFRSLCSDDTPMVRRAAASKLGEFAKVLELD 211
Query: 392 NFHMELYSTFFCLCHDPEVPVRYTIAICFYEVSKLLNSG--VYLIHKELITLLQDESLEV 449
+ E+ F L D + VR +++LL+ L+ L +D+S V
Sbjct: 212 SVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAEDKSWRV 271
Query: 450 LDALIDHLPEILELMSTGGESSVQENKLSSLPDLIPAL------TAAEQRAAASLK 499
+ D E+ + M +L DLIPA AE RAAA+ K
Sbjct: 272 RYMVADRFSELQKAM----------GPKITLNDLIPAFQNLLKDCEAEVRAAAAHK 317
>gi|32455244 beta isoform of regulatory subunit A, protein
phosphatase 2 isoform b [Homo sapiens]
Length = 667
Score = 65.5 bits (158), Expect = 2e-10
Identities = 96/492 (19%), Positives = 195/492 (39%), Gaps = 49/492 (9%)
Query: 176 PLVSKAQLSQTVQSRLVSCKILGKLTNKFDAHTIKREILPLVKSLCQDVEYEVRSCMCRQ 235
PLV + SR +C + + ++ +K EI +SLC D VR +
Sbjct: 142 PLVKRLASGDWFTSRTSACGLFSVCYPRA-SNAVKAEIRQQFRSLCSDDTPMVRRAAASK 200
Query: 236 LENIAQGIGTELTKSVVLPELIELSRDEGSSVRLAAFETLVNLLDIFDTDDRSQTILPLV 295
L A+ + + KS ++P L+ DE SVRL A E V++ + DD ++P +
Sbjct: 201 LGEFAKVLELDSVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTL 260
Query: 296 KSFCE-KSFKADESILISLSFHLGKLCHGLYGIFTPDQHLRFLEFYKKLCTLGLQQENGH 354
+ E KS++ + ++ +L + T + + + K C ++ H
Sbjct: 261 RQAAEDKSWR----VRYMVADRFSELQKAMGPKITLNDLIPAFQNLLKDCEAEVRAAAAH 316
Query: 355 NENQIPPQILEQEKKYISVRKNCAYNFPAMIVFVDPKNFHMELYSTFFCLCHDPEVPVRY 414
++ + ++++ I + + Y EL S D V+
Sbjct: 317 KVKELGENLPIEDRETIIMNQILPY--------------IKELVS-------DTNQHVKS 355
Query: 415 TIAICFYEVSKLLNSGVYLIH--KELITLLQDESLEVLDALIDHLPEILELMSTGGESSV 472
+A +S +L + H + L+DE +V +I +L + E++ +
Sbjct: 356 ALASVIMGLSTILGKENTIEHLLPLFLAQLKDECPDVRLNIISNLDCVNEVI------GI 409
Query: 473 QENKLSSLPDLIPALTAAEQRAAASLKWRTHEKLLQKYACLPHVISSDQIYYRFLQRMFT 532
++ S LP ++ A KWR +++ L + + + L +
Sbjct: 410 RQLSQSLLPAIV--------ELAEDAKWRVRLAIIEYMPLLAGQLGV-EFFDEKLNSLCM 460
Query: 533 IMMTNNVLPVQKAASRTLCIFLRYNRKQEQRHEVIQKLIEQLGQGKSYWNRLRFLDTCEF 592
+ ++V +++AA+ L ++ + ++ ++ K++ + +Y +R+ L
Sbjct: 461 AWLVDHVYAIREAATNNLMKLVQKFGTEWAQNTIVPKVL-VMANDPNYLHRMTTLFCINA 519
Query: 593 IIEIFSKSFFCKYFFLPAIELTHDPVANVRMKLCYLLPKVKSTLKIPADKHLLQQLEMCV 652
+ E + K +++ D VANVR + L K+ L D + LQ V
Sbjct: 520 LSEACGQEITTKQMLPIVLKMAGDQVANVRFNVAKSLQKIGPIL----DTNALQGEVKPV 575
Query: 653 RKLLCQEKDKDV 664
+ L Q++D DV
Sbjct: 576 LQKLGQDEDMDV 587
Score = 42.7 bits (99), Expect = 0.001
Identities = 40/175 (22%), Positives = 74/175 (42%), Gaps = 1/175 (0%)
Query: 122 DESVSIHAYTHSFLQVILLHLEHRDTGVSNAWLETLLSVIEVLPKETLRHEILNPLVSKA 181
+E + I + S L I+ E V A +E + + L E E LN L
Sbjct: 404 NEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFF-DEKLNSLCMAW 462
Query: 182 QLSQTVQSRLVSCKILGKLTNKFDAHTIKREILPLVKSLCQDVEYEVRSCMCRQLENIAQ 241
+ R + L KL KF + I+P V + D Y R + +++
Sbjct: 463 LVDHVYAIREAATNNLMKLVQKFGTEWAQNTIVPKVLVMANDPNYLHRMTTLFCINALSE 522
Query: 242 GIGTELTKSVVLPELIELSRDEGSSVRLAAFETLVNLLDIFDTDDRSQTILPLVK 296
G E+T +LP +++++ D+ ++VR ++L + I DT+ + P+++
Sbjct: 523 ACGQEITTKQMLPIVLKMAGDQVANVRFNVAKSLQKIGPILDTNALQGEVKPVLQ 577
Score = 37.7 bits (86), Expect = 0.047
Identities = 49/197 (24%), Positives = 90/197 (45%), Gaps = 9/197 (4%)
Query: 81 LMRQNPTETLRRVLPKVREALHVAGVEMQLTAAMSF--LTILQDESVSIHAYTHSFLQVI 138
L+ Q+ ETL V+P +R+A ++ A F L ++++ +F Q +
Sbjct: 246 LLSQDDLETL--VMPTLRQAAEDKSWRVRYMVADRFSELQKAMGPKITLNDLIPAF-QNL 302
Query: 139 LLHLEHRDTGVSNAWLETLLSVIEVLPKETLRHEILNPLVSK--AQLSQTVQSRLVSCKI 196
L E + ++ L + + +ET+ + P + + + +Q V+S L S I
Sbjct: 303 LKDCEAEVRAAAAHKVKELGENLPIEDRETIIMNQILPYIKELVSDTNQHVKSALASV-I 361
Query: 197 LGKLTNKFDAHTIKREILPLVKSLCQDVEYEVRSCMCRQLENIAQGIGTELTKSVVLPEL 256
+G T +TI+ +LPL + +D +VR + L+ + + IG +LP +
Sbjct: 362 MGLSTILGKENTIEH-LLPLFLAQLKDECPDVRLNIISNLDCVNEVIGIRQLSQSLLPAI 420
Query: 257 IELSRDEGSSVRLAAFE 273
+EL+ D VRLA E
Sbjct: 421 VELAEDAKWRVRLAIIE 437
Score = 34.3 bits (77), Expect = 0.52
Identities = 68/296 (22%), Positives = 115/296 (38%), Gaps = 31/296 (10%)
Query: 222 QDVEYEVRSCMCRQLENIAQGIGTELTKSVVLPELIELSRDEGSSVRLAAFETLVNLLDI 281
+DV+ + S ++L IA +G E T+S +LP L + DE V LA E L N +
Sbjct: 35 EDVQLRLNSI--KKLSTIALALGVERTRSELLPFLTDTIYDE-DEVLLALAEQLGNFTGL 91
Query: 282 FDTDDRSQTILPLVKSFC--EKSFKADESI--LISLSFHLGKLCHGLYGIFTPDQHLRFL 337
D + +LP +++ E++ D+++ L +S + Y + +
Sbjct: 92 VGGPDFAHCLLPPLENLATVEETVVRDKAVESLRQISQEHTPVALEAYFVPLVKRLASGD 151
Query: 338 EFYKKLCTLGLQQE-NGHNENQIPPQILEQEKKYIS-----VRKNCAYNFPAMIVFVDPK 391
F + GL N + +I +Q + S VR+ A ++
Sbjct: 152 WFTSRTSACGLFSVCYPRASNAVKAEIRQQFRSLCSDDTPMVRRAAASKLGEFAKVLELD 211
Query: 392 NFHMELYSTFFCLCHDPEVPVRYTIAICFYEVSKLLNSG--VYLIHKELITLLQDESLEV 449
+ E+ F L D + VR +++LL+ L+ L +D+S V
Sbjct: 212 SVKSEIVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAEDKSWRV 271
Query: 450 LDALIDHLPEILELMSTGGESSVQENKLSSLPDLIPAL------TAAEQRAAASLK 499
+ D E+ + M +L DLIPA AE RAAA+ K
Sbjct: 272 RYMVADRFSELQKAM----------GPKITLNDLIPAFQNLLKDCEAEVRAAAAHK 317
>gi|4826934 protein phosphatase 4, regulatory subunit 1 isoform b
[Homo sapiens]
Length = 933
Score = 47.4 bits (111), Expect = 6e-05
Identities = 57/265 (21%), Positives = 112/265 (42%), Gaps = 24/265 (9%)
Query: 373 VRKNCAYNFPAMIVFVDPKNFHMELYSTFFCLCHDPEVPVRYTIAICFYEVSKLLNSGVY 432
+ K+CAY+ P + + + +N+H L T+ L D + VR T+A +E++ +L G
Sbjct: 624 IAKHCAYSLPGVALTLGRQNWHC-LRETYETLASDMQWKVRRTLAFSIHELAVIL--GDQ 680
Query: 433 LIHKELITLLQ---DESLEVLDALIDHLPEILELMSTGGESSVQENKLSSLPDLIPALTA 489
L +L+ + + EV ++ HL + L+L+ + + L L L
Sbjct: 681 LTAADLVPIFNGFLKDLDEVRIGVLKHLHDFLKLLHI-------DKRREYLYQLQEFLVT 733
Query: 490 AEQRAAASLKWRTHEKLLQKYACLPHVISSDQIYYRFLQRMFTIMMTNNVLPVQKAASRT 549
R WR +L ++ L + S + Y +L+ + + + V V+ + +
Sbjct: 734 DNSR-----NWRFRAELAEQLILLLELYSPRDV-YDYLRPIALNLCADKVSSVRWISYKL 787
Query: 550 LCIFLRYNRKQEQRH---EVIQKLIEQLGQGKSYWNRLRFLDTCEFIIE--IFSKSFFCK 604
+ ++ ++I +L+E G+ + R F+ C+ +IE F
Sbjct: 788 VSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAV 847
Query: 605 YFFLPAIELTHDPVANVRMKLCYLL 629
+ + L +D V NVR+ L L
Sbjct: 848 HLMPHLLTLANDRVPNVRVLLAKTL 872
Score = 38.5 bits (88), Expect = 0.027
Identities = 76/325 (23%), Positives = 121/325 (37%), Gaps = 46/325 (14%)
Query: 172 EILNPL--VSKAQLSQTVQSR-LVSCKILGKLTNKFDAHTIKREILPLVKSLCQDVEYEV 228
E+L PL + K S+ + +R +V+ +L L D +L + L D E V
Sbjct: 26 EMLTPLGRLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTV 85
Query: 229 RSCMCRQLENIA-------QGIGTELTKSVVLPELIELSRDEGSSVRLAAFETLVNLLDI 281
R+ + Q+ +IA I +K +LP ++ D+ + VR + L+ LL+
Sbjct: 86 RAELMEQVPHIALFCQENRPSIPYAFSK-FLLPIVVRYLADQNNQVRKTSQAALLALLE- 143
Query: 282 FDTDDRSQTILPLVKSFCEKSFKADESILISLSFHLGKLCHGLYGIFTPDQHLRF-LEFY 340
L++ F ++ K+C L + PD + E
Sbjct: 144 ----------QELIERFDVET----------------KVCPVLIELTAPDSNDDVKTEAV 177
Query: 341 KKLCTLGLQQENGHNENQIPPQILEQ--EKKYISVRKNCAYNFPAMIVFVDPKNFHMELY 398
+C + E I P+ E + + VRK CA NF + V + L
Sbjct: 178 AIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATEEMLL 237
Query: 399 STFFCLCHDPEVPVRYTIAICFYEVSKLLNSGV--YLIHKELITLLQDESLEVLDALIDH 456
FF LC D VR A CF VS + + I L+ D S V A
Sbjct: 238 PRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQAAFQS 297
Query: 457 LPEILELM---STGGESSVQENKLS 478
L + S+ G+ +E+K S
Sbjct: 298 LGPFISTFANPSSSGQYFKEESKSS 322
>gi|108936953 protein phosphatase 4, regulatory subunit 1 isoform a
[Homo sapiens]
Length = 950
Score = 47.4 bits (111), Expect = 6e-05
Identities = 57/265 (21%), Positives = 112/265 (42%), Gaps = 24/265 (9%)
Query: 373 VRKNCAYNFPAMIVFVDPKNFHMELYSTFFCLCHDPEVPVRYTIAICFYEVSKLLNSGVY 432
+ K+CAY+ P + + + +N+H L T+ L D + VR T+A +E++ +L G
Sbjct: 641 IAKHCAYSLPGVALTLGRQNWHC-LRETYETLASDMQWKVRRTLAFSIHELAVIL--GDQ 697
Query: 433 LIHKELITLLQ---DESLEVLDALIDHLPEILELMSTGGESSVQENKLSSLPDLIPALTA 489
L +L+ + + EV ++ HL + L+L+ + + L L L
Sbjct: 698 LTAADLVPIFNGFLKDLDEVRIGVLKHLHDFLKLLHI-------DKRREYLYQLQEFLVT 750
Query: 490 AEQRAAASLKWRTHEKLLQKYACLPHVISSDQIYYRFLQRMFTIMMTNNVLPVQKAASRT 549
R WR +L ++ L + S + Y +L+ + + + V V+ + +
Sbjct: 751 DNSR-----NWRFRAELAEQLILLLELYSPRDV-YDYLRPIALNLCADKVSSVRWISYKL 804
Query: 550 LCIFLRYNRKQEQRH---EVIQKLIEQLGQGKSYWNRLRFLDTCEFIIE--IFSKSFFCK 604
+ ++ ++I +L+E G+ + R F+ C+ +IE F
Sbjct: 805 VSEMVKKLHAATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAV 864
Query: 605 YFFLPAIELTHDPVANVRMKLCYLL 629
+ + L +D V NVR+ L L
Sbjct: 865 HLMPHLLTLANDRVPNVRVLLAKTL 889
Score = 38.5 bits (88), Expect = 0.027
Identities = 76/325 (23%), Positives = 121/325 (37%), Gaps = 46/325 (14%)
Query: 172 EILNPL--VSKAQLSQTVQSR-LVSCKILGKLTNKFDAHTIKREILPLVKSLCQDVEYEV 228
E+L PL + K S+ + +R +V+ +L L D +L + L D E V
Sbjct: 43 EMLTPLGRLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTV 102
Query: 229 RSCMCRQLENIA-------QGIGTELTKSVVLPELIELSRDEGSSVRLAAFETLVNLLDI 281
R+ + Q+ +IA I +K +LP ++ D+ + VR + L+ LL+
Sbjct: 103 RAELMEQVPHIALFCQENRPSIPYAFSK-FLLPIVVRYLADQNNQVRKTSQAALLALLE- 160
Query: 282 FDTDDRSQTILPLVKSFCEKSFKADESILISLSFHLGKLCHGLYGIFTPDQHLRF-LEFY 340
L++ F ++ K+C L + PD + E
Sbjct: 161 ----------QELIERFDVET----------------KVCPVLIELTAPDSNDDVKTEAV 194
Query: 341 KKLCTLGLQQENGHNENQIPPQILEQ--EKKYISVRKNCAYNFPAMIVFVDPKNFHMELY 398
+C + E I P+ E + + VRK CA NF + V + L
Sbjct: 195 AIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATEEMLL 254
Query: 399 STFFCLCHDPEVPVRYTIAICFYEVSKLLNSGV--YLIHKELITLLQDESLEVLDALIDH 456
FF LC D VR A CF VS + + I L+ D S V A
Sbjct: 255 PRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQAAFQS 314
Query: 457 LPEILELM---STGGESSVQENKLS 478
L + S+ G+ +E+K S
Sbjct: 315 LGPFISTFANPSSSGQYFKEESKSS 339
>gi|150456424 RW1 protein [Homo sapiens]
Length = 1883
Score = 42.7 bits (99), Expect = 0.001
Identities = 56/221 (25%), Positives = 94/221 (42%), Gaps = 47/221 (21%)
Query: 696 DQEKEREELLLLEMEQLEKEKQQNDGRPMSDKMFEKKRR---DTKTPTQSLP-------- 744
D EK++ + + E + E + + + S K+ K+ D K + LP
Sbjct: 1441 DTEKQKGKQAMPE----KHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLESK 1496
Query: 745 --KNIPISVPGPSSVTP-STSKEIKKSKLIRSQSFNNQAFHAKY-GNLEKCASKSSTTGY 800
+N+P +P P+++T S S+ +K+K N AK+ N ++ + SS+ G
Sbjct: 1497 QRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNSQELGNTSSSEGE 1556
Query: 801 T----------------TSVSGLGKTSVLSLADDSF-RTRNASSVPSSFSPNT-PLPSTS 842
+S L K S+ +L D F + R S P+S SP P P +
Sbjct: 1557 KDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPAAPCPFVA 1616
Query: 843 RGTGNSV-------DPK---SSGSKDTQPRKATLKSRKSNP 873
RG+ +S+ DPK +GSK + A+L + NP
Sbjct: 1617 RGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASLPGKNGNP 1657
>gi|239755778 PREDICTED: mucin 19, oligomeric [Homo sapiens]
Length = 598
Score = 40.4 bits (93), Expect = 0.007
Identities = 33/129 (25%), Positives = 61/129 (47%), Gaps = 6/129 (4%)
Query: 736 TKTPTQSLPKNIPISVPGPSSVTPSTSKEIKKSKLIRSQSFNNQAFHAKYGNLEKCASKS 795
+KT T + + ++ PG SS +TS + ++ ++ ++ AK G + +
Sbjct: 49 SKTGTTGVALSTTVA-PGSSSTEATTSTGVHRTTVVGQKTGATTRGSAKQGTRSTIEATT 107
Query: 796 STTGYTTSVSGL--GKTSVLS---LADDSFRTRNASSVPSSFSPNTPLPSTSRGTGNSVD 850
S G T+ SG+ G T V+S ++ SF T S +P + + +T +G +V
Sbjct: 108 SFRGTGTTGSGMNTGTTGVVSGNTISPSSFNTEATSGTSERPNPGSEIGTTGIVSGTTVA 167
Query: 851 PKSSGSKDT 859
P SS ++ T
Sbjct: 168 PGSSNTEAT 176
>gi|239750280 PREDICTED: mucin 19, oligomeric [Homo sapiens]
Length = 598
Score = 40.4 bits (93), Expect = 0.007
Identities = 33/129 (25%), Positives = 61/129 (47%), Gaps = 6/129 (4%)
Query: 736 TKTPTQSLPKNIPISVPGPSSVTPSTSKEIKKSKLIRSQSFNNQAFHAKYGNLEKCASKS 795
+KT T + + ++ PG SS +TS + ++ ++ ++ AK G + +
Sbjct: 49 SKTGTTGVALSTTVA-PGSSSTEATTSTGVHRTTVVGQKTGATTRGSAKQGTRSTIEATT 107
Query: 796 STTGYTTSVSGL--GKTSVLS---LADDSFRTRNASSVPSSFSPNTPLPSTSRGTGNSVD 850
S G T+ SG+ G T V+S ++ SF T S +P + + +T +G +V
Sbjct: 108 SFRGTGTTGSGMNTGTTGVVSGNTISPSSFNTEATSGTSERPNPGSEIGTTGIVSGTTVA 167
Query: 851 PKSSGSKDT 859
P SS ++ T
Sbjct: 168 PGSSNTEAT 176
>gi|239744589 PREDICTED: mucin 19 [Homo sapiens]
Length = 598
Score = 40.4 bits (93), Expect = 0.007
Identities = 33/129 (25%), Positives = 61/129 (47%), Gaps = 6/129 (4%)
Query: 736 TKTPTQSLPKNIPISVPGPSSVTPSTSKEIKKSKLIRSQSFNNQAFHAKYGNLEKCASKS 795
+KT T + + ++ PG SS +TS + ++ ++ ++ AK G + +
Sbjct: 49 SKTGTTGVALSTTVA-PGSSSTEATTSTGVHRTTVVGQKTGATTRGSAKQGTRSTIEATT 107
Query: 796 STTGYTTSVSGL--GKTSVLS---LADDSFRTRNASSVPSSFSPNTPLPSTSRGTGNSVD 850
S G T+ SG+ G T V+S ++ SF T S +P + + +T +G +V
Sbjct: 108 SFRGTGTTGSGMNTGTTGVVSGNTISPSSFNTEATSGTSERPNPGSEIGTTGIVSGTTVA 167
Query: 851 PKSSGSKDT 859
P SS ++ T
Sbjct: 168 PGSSNTEAT 176
>gi|122937227 U2-associated SR140 protein [Homo sapiens]
Length = 1029
Score = 40.0 bits (92), Expect = 0.009
Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 34/187 (18%)
Query: 686 QKKFYEKDLLDQEKEREELLLLEMEQLEKEKQQNDGRPMSDKMFEKKRRDTKTPTQSLPK 745
Q + Y LL +EKE+E + E+E+ + D + + +KK +D TPT+ K
Sbjct: 874 QVEHYRDKLLQREKEKEL-------ERERERDKKDKEKLESRSKDKKEKDECTPTRKERK 926
Query: 746 NIPISVPGPSSVTPSTSKEIKKSKLIRSQSFNNQAFHAKYGNLEKCASKSSTTGYTTSVS 805
+ P PS S+ + +K +S ++ H E S+SS VS
Sbjct: 927 RRHSTSPSPS--RSSSGRRVKSPSPKSERSERSERSHK-----ESSRSRSSHKDSPRDVS 979
Query: 806 GLGKTSVLSLADDSFRTRNASSVPS-SFSPNTPLPSTSRGTGNSVDPKSSGSKDTQPRKA 864
K S PS S +P S SR S K S S+ P ++
Sbjct: 980 KKAKRS-----------------PSGSRTPKRSRRSRSRSPKKS--GKKSRSQSRSPHRS 1020
Query: 865 TLKSRKS 871
KS+K+
Sbjct: 1021 HKKSKKN 1027
>gi|33457330 tetratricopeptide repeat domain 14 isoform a [Homo
sapiens]
Length = 770
Score = 39.3 bits (90), Expect = 0.016
Identities = 40/146 (27%), Positives = 70/146 (47%), Gaps = 4/146 (2%)
Query: 640 ADKHLLQQLEMCVRKLLCQEKDKDVLAIVKRTVLELDRMEMSMDAFQK--KFYEKDLLDQ 697
A K+L Q L +L +EK + + K+ + + + + DA QK K+ +K L +
Sbjct: 377 ARKYLCQTLVERGGQLEEEEKFLNAESYYKKALALDETFKDAEDALQKLHKYMQKSLELR 436
Query: 698 EKEREELLLLEMEQLEKEKQQNDGRPMSDKMFEKKRRDTKTPTQSLPKNIPISVPGPSSV 757
EK+ E+ + +++E ++ +K +KKRR K+ + S + SV SS
Sbjct: 437 EKQAEKEEKQKTKKIETSAEKLRKLLKEEKRLKKKRR--KSTSSSSVSSADESVSSSSSS 494
Query: 758 TPSTSKEIKKSKLIRSQSFNNQAFHA 783
+ S K KK K RS+S + H+
Sbjct: 495 SSSGHKRHKKHKRNRSESSRSSRRHS 520
>gi|219842214 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform b [Homo sapiens]
Length = 943
Score = 38.1 bits (87), Expect = 0.036
Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Query: 697 QEKEREELLLLEMEQLEKEKQQNDGRPMSDKMFEKKRRDTKTPTQSLPKNIPISVPGPSS 756
+E+E EE E E+ +KEKQ+ + + E K++ ++T ++ + P+S SS
Sbjct: 633 REQENEEKEKEEKEKQDKEKQEEKKESETSREDEYKQKYSRTYDETYQRYRPVST--SSS 690
Query: 757 VTPSTSKEIKKSKLIRSQSFN 777
TPS+S S L S N
Sbjct: 691 TTPSSSLSTMSSSLYASSQLN 711
>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 38.1 bits (87), Expect = 0.036
Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Query: 697 QEKEREELLLLEMEQLEKEKQQNDGRPMSDKMFEKKRRDTKTPTQSLPKNIPISVPGPSS 756
+E+E EE E E+ +KEKQ+ + + E K++ ++T ++ + P+S SS
Sbjct: 720 REQENEEKEKEEKEKQDKEKQEEKKESETSREDEYKQKYSRTYDETYQRYRPVST--SSS 777
Query: 757 VTPSTSKEIKKSKLIRSQSFN 777
TPS+S S L S N
Sbjct: 778 TTPSSSLSTMSSSLYASSQLN 798
>gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 38.1 bits (87), Expect = 0.036
Identities = 25/81 (30%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Query: 697 QEKEREELLLLEMEQLEKEKQQNDGRPMSDKMFEKKRRDTKTPTQSLPKNIPISVPGPSS 756
+E+E EE E E+ +KEKQ+ + + E K++ ++T ++ + P+S SS
Sbjct: 720 REQENEEKEKEEKEKQDKEKQEEKKESETSREDEYKQKYSRTYDETYQRYRPVST--SSS 777
Query: 757 VTPSTSKEIKKSKLIRSQSFN 777
TPS+S S L S N
Sbjct: 778 TTPSSSLSTMSSSLYASSQLN 798
>gi|28376658 hypothetical protein LOC285172 [Homo sapiens]
Length = 530
Score = 38.1 bits (87), Expect = 0.036
Identities = 33/133 (24%), Positives = 60/133 (45%), Gaps = 9/133 (6%)
Query: 210 KREILPLVKSLCQDVEYEVRSCMCRQLENIAQGIGTELTKSVV--LPEL------IELSR 261
K+ ++P + + QD E+ +C QL + + L + + LPEL + +SR
Sbjct: 34 KKTLVPALYKVIQDSNNELLEPVCHQLFELYRSSEVRLKRFTLQFLPELMWVYLRLTVSR 93
Query: 262 DEGSSVRLAAFETLVNLLDIFDTDDRSQTILPLVKSFCEKSFKADESILISLSFHLGKLC 321
D S+ + A + L+I D D ++ + + S + S + S + S++ G LC
Sbjct: 94 DRQSNGCIEALLLGIYNLEIADKDGNNKVLSFTIPSLSKPSIYHEPSTIGSMALTEGALC 153
Query: 322 -HGLYGIFTPDQH 333
H L + D H
Sbjct: 154 QHDLIRVVYSDLH 166
>gi|40805104 topoisomerase I binding, arginine/serine-rich [Homo
sapiens]
Length = 1045
Score = 37.0 bits (84), Expect = 0.080
Identities = 35/145 (24%), Positives = 62/145 (42%), Gaps = 13/145 (8%)
Query: 712 LEKEKQQNDGRPMSDKMFEKKRRDTKTPTQSLPKNIPISVPGPSSVTPSTSKEIKKSK-- 769
L K++Q N G S + K+ + ++ + S P+N+ SV G +P + K+ +
Sbjct: 539 LGKDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSR 598
Query: 770 ----LIRSQSFNNQAFHAKYGNLEKCASKSSTTGYTTSVSGLGKTSVLSLADDSFRTRNA 825
+S+S ++Q H K+ ++ SK S + ++ G D S+ R+
Sbjct: 599 SSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQ 658
Query: 826 SSVPSSFSPNTPLPSTSRGTGNSVD 850
+ SS STSR S D
Sbjct: 659 TLSLSS-------ESTSRSRSRSSD 676
>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
Length = 4377
Score = 37.0 bits (84), Expect = 0.080
Identities = 40/146 (27%), Positives = 58/146 (39%), Gaps = 28/146 (19%)
Query: 723 PMSDKMFEKKRRDTKTPTQSLPKNIPISVPGPSSVTPSTSK-EIKKSKLIRSQSFNNQAF 781
P F K+ + TK Q+ N+ I++P T S EI+K+ R QSF + A
Sbjct: 1408 PCGRLSFLKEPKTTKGLPQTAVCNLNITLPAHKKETESDQDDEIEKTD--RRQSFASLAL 1465
Query: 782 HAKYGNLEKCASKSSTTGYTTS-------------------------VSGLGKTSVLSLA 816
+Y L + +TG T S V G K+ SL+
Sbjct: 1466 RKRYSYLTEPGMIERSTGATRSLPTTYSYKPFFSTRPYQSWTTAPITVPGPAKSGFTSLS 1525
Query: 817 DDSFRTRNASSVPSSFSPNTPLPSTS 842
S T +AS + S +S +TP P S
Sbjct: 1526 SSSSNTPSASPLKSIWSVSTPSPIKS 1551
>gi|189011568 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 36.6 bits (83), Expect = 0.10
Identities = 41/170 (24%), Positives = 69/170 (40%), Gaps = 24/170 (14%)
Query: 708 EMEQLEKEKQQNDGRPMSDKMFEKKRRDTKTPTQSLPKNIPISVPGPSSVTPST---SKE 764
E+ + ++ Q G + + P Q P + PI PG +S++P S
Sbjct: 2281 ELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQ-PLSRPIQSPGRNSISPGRNGISPP 2339
Query: 765 IKKSKLIRSQSFNNQAFHAKYGNLEKCASKSSTTGYTTSVSGLGKTSVLSLADDSFRTRN 824
K S+L R+ S + ++KSS +G + S + S +L + ++N
Sbjct: 2340 NKLSQLPRTSSPST------------ASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKN 2387
Query: 825 ASSVPSSFSPNTPLPSTSRGTG--------NSVDPKSSGSKDTQPRKATL 866
ASS+P S S + L + G G KSSGS+ + + L
Sbjct: 2388 ASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVL 2437
Score = 34.3 bits (77), Expect = 0.52
Identities = 51/241 (21%), Positives = 85/241 (35%), Gaps = 33/241 (13%)
Query: 632 VKSTLKIPADKHLLQQLEMCVRKLLCQEKDKDVLAIVKRTVLELDRMEMSMDAFQ--KKF 689
+KS + + + HL E K K +L +++ LE ++E + KK
Sbjct: 2138 LKSGISLGSPFHLTPDQE---EKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKV 2194
Query: 690 YEKDLLDQEKEREELLLLEMEQLEKEKQQ-NDGRPM-----------SDKMFEKKRRDTK 737
Y+ + + + E+ + L+ + GR M S KK K
Sbjct: 2195 YKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLK 2254
Query: 738 TPTQSLPKNIPISVPGPSSVTPSTSKEIKKSKLIRSQSFNNQAFHAKYGNLEKCASKSST 797
TP P + P PS E+ SQ + ++ G+ + S+ +
Sbjct: 2255 TPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQ 2314
Query: 798 TGYTTSVSGLGKTSVLSLADDSFRTRNASSVPSSFS--PNTPLPSTSRGTGNSVDPKSSG 855
+ + G+ S+ RN S P+ S P T PST+ KSSG
Sbjct: 2315 QPLSRPIQSPGRNSISP-------GRNGISPPNKLSQLPRTSSPSTA-------STKSSG 2360
Query: 856 S 856
S
Sbjct: 2361 S 2361
Score = 32.0 bits (71), Expect = 2.6
Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
Query: 800 YTTSVSGLGKTSVLSLADDSFRTRNASSVPSSFSPNTPLPSTSRGTGNSVDPKSSGSKDT 859
Y T + K S S + S + + SS S NT PS++ N + P S+ S+
Sbjct: 1183 YATDIPSSQKQS-FSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSG 1241
Query: 860 QPRKA 864
QP+KA
Sbjct: 1242 QPQKA 1246
>gi|189011566 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 36.6 bits (83), Expect = 0.10
Identities = 41/170 (24%), Positives = 69/170 (40%), Gaps = 24/170 (14%)
Query: 708 EMEQLEKEKQQNDGRPMSDKMFEKKRRDTKTPTQSLPKNIPISVPGPSSVTPST---SKE 764
E+ + ++ Q G + + P Q P + PI PG +S++P S
Sbjct: 2281 ELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQ-PLSRPIQSPGRNSISPGRNGISPP 2339
Query: 765 IKKSKLIRSQSFNNQAFHAKYGNLEKCASKSSTTGYTTSVSGLGKTSVLSLADDSFRTRN 824
K S+L R+ S + ++KSS +G + S + S +L + ++N
Sbjct: 2340 NKLSQLPRTSSPST------------ASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKN 2387
Query: 825 ASSVPSSFSPNTPLPSTSRGTG--------NSVDPKSSGSKDTQPRKATL 866
ASS+P S S + L + G G KSSGS+ + + L
Sbjct: 2388 ASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVL 2437
Score = 34.3 bits (77), Expect = 0.52
Identities = 51/241 (21%), Positives = 85/241 (35%), Gaps = 33/241 (13%)
Query: 632 VKSTLKIPADKHLLQQLEMCVRKLLCQEKDKDVLAIVKRTVLELDRMEMSMDAFQ--KKF 689
+KS + + + HL E K K +L +++ LE ++E + KK
Sbjct: 2138 LKSGISLGSPFHLTPDQE---EKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKV 2194
Query: 690 YEKDLLDQEKEREELLLLEMEQLEKEKQQ-NDGRPM-----------SDKMFEKKRRDTK 737
Y+ + + + E+ + L+ + GR M S KK K
Sbjct: 2195 YKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLK 2254
Query: 738 TPTQSLPKNIPISVPGPSSVTPSTSKEIKKSKLIRSQSFNNQAFHAKYGNLEKCASKSST 797
TP P + P PS E+ SQ + ++ G+ + S+ +
Sbjct: 2255 TPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQ 2314
Query: 798 TGYTTSVSGLGKTSVLSLADDSFRTRNASSVPSSFS--PNTPLPSTSRGTGNSVDPKSSG 855
+ + G+ S+ RN S P+ S P T PST+ KSSG
Sbjct: 2315 QPLSRPIQSPGRNSISP-------GRNGISPPNKLSQLPRTSSPSTA-------STKSSG 2360
Query: 856 S 856
S
Sbjct: 2361 S 2361
Score = 32.0 bits (71), Expect = 2.6
Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
Query: 800 YTTSVSGLGKTSVLSLADDSFRTRNASSVPSSFSPNTPLPSTSRGTGNSVDPKSSGSKDT 859
Y T + K S S + S + + SS S NT PS++ N + P S+ S+
Sbjct: 1183 YATDIPSSQKQS-FSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSG 1241
Query: 860 QPRKA 864
QP+KA
Sbjct: 1242 QPQKA 1246
>gi|53759122 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 36.6 bits (83), Expect = 0.10
Identities = 41/170 (24%), Positives = 69/170 (40%), Gaps = 24/170 (14%)
Query: 708 EMEQLEKEKQQNDGRPMSDKMFEKKRRDTKTPTQSLPKNIPISVPGPSSVTPST---SKE 764
E+ + ++ Q G + + P Q P + PI PG +S++P S
Sbjct: 2281 ELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQQ-PLSRPIQSPGRNSISPGRNGISPP 2339
Query: 765 IKKSKLIRSQSFNNQAFHAKYGNLEKCASKSSTTGYTTSVSGLGKTSVLSLADDSFRTRN 824
K S+L R+ S + ++KSS +G + S + S +L + ++N
Sbjct: 2340 NKLSQLPRTSSPST------------ASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKN 2387
Query: 825 ASSVPSSFSPNTPLPSTSRGTG--------NSVDPKSSGSKDTQPRKATL 866
ASS+P S S + L + G G KSSGS+ + + L
Sbjct: 2388 ASSIPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVL 2437
Score = 34.3 bits (77), Expect = 0.52
Identities = 51/241 (21%), Positives = 85/241 (35%), Gaps = 33/241 (13%)
Query: 632 VKSTLKIPADKHLLQQLEMCVRKLLCQEKDKDVLAIVKRTVLELDRMEMSMDAFQ--KKF 689
+KS + + + HL E K K +L +++ LE ++E + KK
Sbjct: 2138 LKSGISLGSPFHLTPDQE---EKPFTSNKGPRILKPGEKSTLETKKIESESKGIKGGKKV 2194
Query: 690 YEKDLLDQEKEREELLLLEMEQLEKEKQQ-NDGRPM-----------SDKMFEKKRRDTK 737
Y+ + + + E+ + L+ + GR M S KK K
Sbjct: 2195 YKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLK 2254
Query: 738 TPTQSLPKNIPISVPGPSSVTPSTSKEIKKSKLIRSQSFNNQAFHAKYGNLEKCASKSST 797
TP P + P PS E+ SQ + ++ G+ + S+ +
Sbjct: 2255 TPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTSQIGGSSKAPSRSGSRDSTPSRPAQ 2314
Query: 798 TGYTTSVSGLGKTSVLSLADDSFRTRNASSVPSSFS--PNTPLPSTSRGTGNSVDPKSSG 855
+ + G+ S+ RN S P+ S P T PST+ KSSG
Sbjct: 2315 QPLSRPIQSPGRNSISP-------GRNGISPPNKLSQLPRTSSPSTA-------STKSSG 2360
Query: 856 S 856
S
Sbjct: 2361 S 2361
Score = 32.0 bits (71), Expect = 2.6
Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
Query: 800 YTTSVSGLGKTSVLSLADDSFRTRNASSVPSSFSPNTPLPSTSRGTGNSVDPKSSGSKDT 859
Y T + K S S + S + + SS S NT PS++ N + P S+ S+
Sbjct: 1183 YATDIPSSQKQS-FSFSKSSSGQSSKTEHMSSSSENTSTPSSNAKRQNQLHPSSAQSRSG 1241
Query: 860 QPRKA 864
QP+KA
Sbjct: 1242 QPQKA 1246
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 36.2 bits (82), Expect = 0.14
Identities = 28/102 (27%), Positives = 55/102 (53%), Gaps = 13/102 (12%)
Query: 673 LELDRMEMSMDAFQKKFYEKDL--LDQEKEREELLLLEMEQLEKEKQQNDGRP--MSDKM 728
L+ ++ ++ D KK ++ + L+++K++E+ E+++ KE ++++GR D
Sbjct: 388 LKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKK---EIKKERKELKKDEGRKEEKKDAK 444
Query: 729 FEKKRRDTKTPTQSLPKNIPISVPGPSSVTPSTSKEIKKSKL 770
E+KR+DTK P+ IS P TP K + K+K+
Sbjct: 445 KEEKRKDTK------PELKKISKPDLKPFTPEVRKTLYKAKV 480
>gi|47578107 delangin isoform B [Homo sapiens]
Length = 2697
Score = 36.2 bits (82), Expect = 0.14
Identities = 35/162 (21%), Positives = 65/162 (40%), Gaps = 7/162 (4%)
Query: 713 EKEKQQNDGRPMSDKMFEKKRRDTKTPTQSLPKNIPISVPGPSSVTPSTSKEIKKSKLIR 772
E KQ+N+GRP + K RRD+ P+ + S +P E ++ R
Sbjct: 745 ETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVSKHKQDTKSDSPRLKSERAEALKQR 804
Query: 773 SQSFN-NQAFHAKYGNLEKCASKSSTTGYTTSVSGLGKTSVLSLADDSFRTRNASSVPSS 831
+ +++ + N +K + + + S + + L + +RN + S
Sbjct: 805 PDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRVRRPETLRSS-----SRNEHGIKSD 859
Query: 832 FSPNTPLPSTSR-GTGNSVDPKSSGSKDTQPRKATLKSRKSN 872
S L R +G+S + SSG + ++P +K SN
Sbjct: 860 SSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDSN 901
>gi|47578105 delangin isoform A [Homo sapiens]
Length = 2804
Score = 36.2 bits (82), Expect = 0.14
Identities = 35/162 (21%), Positives = 65/162 (40%), Gaps = 7/162 (4%)
Query: 713 EKEKQQNDGRPMSDKMFEKKRRDTKTPTQSLPKNIPISVPGPSSVTPSTSKEIKKSKLIR 772
E KQ+N+GRP + K RRD+ P+ + S +P E ++ R
Sbjct: 745 ETPKQKNEGRPETPKHRHDNRRDSGKPSTEKKPEVSKHKQDTKSDSPRLKSERAEALKQR 804
Query: 773 SQSFN-NQAFHAKYGNLEKCASKSSTTGYTTSVSGLGKTSVLSLADDSFRTRNASSVPSS 831
+ +++ + N +K + + + S + + L + +RN + S
Sbjct: 805 PDGRSVSESLRRDHDNKQKSDDRGESERHRGDQSRVRRPETLRSS-----SRNEHGIKSD 859
Query: 832 FSPNTPLPSTSR-GTGNSVDPKSSGSKDTQPRKATLKSRKSN 872
S L R +G+S + SSG + ++P +K SN
Sbjct: 860 SSKTDKLERKHRHESGDSRERPSSGEQKSRPDSPRVKQGDSN 901
>gi|115430243 SCY1-like 1 isoform B [Homo sapiens]
Length = 791
Score = 35.8 bits (81), Expect = 0.18
Identities = 31/185 (16%), Positives = 81/185 (43%), Gaps = 7/185 (3%)
Query: 137 VILLHLEHRDTGVSNAWLETLLSVIEVLPKETLRHEILNPLVSKAQLSQTVQSRLVSCKI 196
+ L ++ ++ + + L ++ P++ RH++L L++ + L
Sbjct: 277 LFLEEIQIKEPAEKQKFFQELSKSLDAFPEDFCRHKVLPQLLTAFEFGNAGAVVLTPLFK 336
Query: 197 LGKLTNKFDAHTIKREILPLVKSLCQDVEYEVRSCMCRQLENIAQGIGTELTKSVVLPEL 256
+GK + A +++I+P+V + + +R + +Q+E Q + + + P +
Sbjct: 337 VGKFLS---AEEYQQKIIPVVVKMFSSTDRAMRIRLLQQMEQFIQYLDEPTVNTQIFPHV 393
Query: 257 IELSRDEGSSVRLAAFETLVNLLDIFDTDDRSQTILPLVKSFCEKSFKADES-ILISLSF 315
+ D ++R +T+ ++L + + + + L+K F K ++ I + +
Sbjct: 394 VHGFLDTNPAIR---EQTVKSMLLLAPKLNEANLNVELMKHFARLQAKDEQGPIRCNTTV 450
Query: 316 HLGKL 320
LGK+
Sbjct: 451 CLGKI 455
>gi|115430241 SCY1-like 1 isoform A [Homo sapiens]
Length = 808
Score = 35.8 bits (81), Expect = 0.18
Identities = 31/185 (16%), Positives = 81/185 (43%), Gaps = 7/185 (3%)
Query: 137 VILLHLEHRDTGVSNAWLETLLSVIEVLPKETLRHEILNPLVSKAQLSQTVQSRLVSCKI 196
+ L ++ ++ + + L ++ P++ RH++L L++ + L
Sbjct: 277 LFLEEIQIKEPAEKQKFFQELSKSLDAFPEDFCRHKVLPQLLTAFEFGNAGAVVLTPLFK 336
Query: 197 LGKLTNKFDAHTIKREILPLVKSLCQDVEYEVRSCMCRQLENIAQGIGTELTKSVVLPEL 256
+GK + A +++I+P+V + + +R + +Q+E Q + + + P +
Sbjct: 337 VGKFLS---AEEYQQKIIPVVVKMFSSTDRAMRIRLLQQMEQFIQYLDEPTVNTQIFPHV 393
Query: 257 IELSRDEGSSVRLAAFETLVNLLDIFDTDDRSQTILPLVKSFCEKSFKADES-ILISLSF 315
+ D ++R +T+ ++L + + + + L+K F K ++ I + +
Sbjct: 394 VHGFLDTNPAIR---EQTVKSMLLLAPKLNEANLNVELMKHFARLQAKDEQGPIRCNTTV 450
Query: 316 HLGKL 320
LGK+
Sbjct: 451 CLGKI 455
>gi|164419758 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 35.8 bits (81), Expect = 0.18
Identities = 40/146 (27%), Positives = 65/146 (44%), Gaps = 10/146 (6%)
Query: 637 KIPADK-----HLLQQLEMCVRKLLCQEKDKDVLAIVKRTVLELDRMEMSMDAFQKKFYE 691
K+P +K H++Q E +R +E + D + T+ EL+R +S +KK +
Sbjct: 656 KLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLS--CLRKKPRK 713
Query: 692 KDLLDQE--KEREELLLLEMEQLEKEKQQNDGRPMSDKMFEKKRRDTKTPTQSLPKNIPI 749
+ + K +EEL L + +LEK Q G+ S K KK + KT + S +
Sbjct: 714 PYTIKKPVGKTKEELALEKKRELEKRLQDVSGQLNSTKKPPKKANE-KTESSSAQQVAVS 772
Query: 750 SVPGPSSVTPSTSKEIKKSKLIRSQS 775
+ SS + S+S S S S
Sbjct: 773 RLSASSSSSDSSSSSSSSSSSDTSDS 798
>gi|4826806 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 35.8 bits (81), Expect = 0.18
Identities = 40/146 (27%), Positives = 65/146 (44%), Gaps = 10/146 (6%)
Query: 637 KIPADK-----HLLQQLEMCVRKLLCQEKDKDVLAIVKRTVLELDRMEMSMDAFQKKFYE 691
K+P +K H++Q E +R +E + D + T+ EL+R +S +KK +
Sbjct: 656 KLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRELERYVLS--CLRKKPRK 713
Query: 692 KDLLDQE--KEREELLLLEMEQLEKEKQQNDGRPMSDKMFEKKRRDTKTPTQSLPKNIPI 749
+ + K +EEL L + +LEK Q G+ S K KK + KT + S +
Sbjct: 714 PYTIKKPVGKTKEELALEKKRELEKRLQDVSGQLNSTKKPPKKANE-KTESSSAQQVAVS 772
Query: 750 SVPGPSSVTPSTSKEIKKSKLIRSQS 775
+ SS + S+S S S S
Sbjct: 773 RLSASSSSSDSSSSSSSSSSSDTSDS 798
>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
Length = 726
Score = 35.8 bits (81), Expect = 0.18
Identities = 39/148 (26%), Positives = 60/148 (40%), Gaps = 22/148 (14%)
Query: 637 KIPADK-----HLLQQLEMCVRKLLCQEKDKDVLAIVKRTVLELDRMEMSMDAFQKK--- 688
++P +K H++Q E +R E + D + T+ EL+R S QKK
Sbjct: 586 RLPGEKLGRVVHIIQSREPSLRDSNPDEIEIDFETLKPTTLRELERYVKS--CLQKKQRK 643
Query: 689 -FYEKDLLDQEKEREELLLLEMEQLEKEKQQNDGRPMSDKMFEKKRRDTKTPTQSLPKNI 747
F K +EEL + ++LEK Q G+ S K +K + P+
Sbjct: 644 PFSASGKKQAAKSKEELAQEKKKELEKRLQDVSGQLSSSKKPARKEKPGSAPS------- 696
Query: 748 PISVPGPSSVTPSTSKEIKKSKLIRSQS 775
GPS ++ S+S E S S S
Sbjct: 697 ----GGPSRLSSSSSSESGSSSSSGSSS 720
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,335,853
Number of Sequences: 37866
Number of extensions: 1464743
Number of successful extensions: 7603
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 173
Number of HSP's that attempted gapping in prelim test: 7107
Number of HSP's gapped (non-prelim): 604
length of query: 873
length of database: 18,247,518
effective HSP length: 111
effective length of query: 762
effective length of database: 14,044,392
effective search space: 10701826704
effective search space used: 10701826704
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.