BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|17318565 cyclin E2 [Homo sapiens] (404 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|17318565 cyclin E2 [Homo sapiens] 822 0.0 gi|17318559 cyclin E1 isoform 1 [Homo sapiens] 364 e-101 gi|17318561 cyclin E1 isoform 2 [Homo sapiens] 364 e-101 gi|161377472 cyclin A1 isoform c [Homo sapiens] 103 4e-22 gi|161377470 cyclin A1 isoform c [Homo sapiens] 103 4e-22 gi|161377468 cyclin A1 isoform b [Homo sapiens] 103 4e-22 gi|4502611 cyclin A1 isoform a [Homo sapiens] 103 4e-22 gi|4502613 cyclin A [Homo sapiens] 100 3e-21 gi|4757930 cyclin B2 [Homo sapiens] 99 7e-21 gi|14327896 cyclin B1 [Homo sapiens] 97 3e-20 gi|16950655 cyclin D1 [Homo sapiens] 93 4e-19 gi|4502617 cyclin D2 [Homo sapiens] 89 9e-18 gi|4502619 cyclin D3 isoform 2 [Homo sapiens] 86 5e-17 gi|90669307 cyclin B3 isoform 3 [Homo sapiens] 77 2e-14 gi|5802992 cyclin I [Homo sapiens] 74 2e-13 gi|153791755 cyclin domain containing [Homo sapiens] 62 9e-10 gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Ho... 61 2e-09 gi|89886237 cyclin I family, member 2 [Homo sapiens] 59 1e-08 gi|16306525 cyclin B3 isoform 1 [Homo sapiens] 56 7e-08 gi|4757936 cyclin G2 [Homo sapiens] 54 3e-07 gi|118572588 cyclin F [Homo sapiens] 52 1e-06 gi|197276674 cyclin J isoform 1 [Homo sapiens] 49 6e-06 gi|209862835 cyclin D3 isoform 1 [Homo sapiens] 48 1e-05 gi|40254889 cyclin J isoform 2 [Homo sapiens] 47 2e-05 gi|40805832 cyclin G1 [Homo sapiens] 47 4e-05 gi|4757934 cyclin G1 [Homo sapiens] 47 4e-05 gi|197276676 cyclin J isoform 3 [Homo sapiens] 47 4e-05 gi|94680985 cyclin J-like [Homo sapiens] 36 0.071 gi|209915553 cyclin D3 isoform 3 [Homo sapiens] 35 0.12 gi|187173292 troponin T1, skeletal, slow isoform c [Homo sapiens] 33 0.60 >gi|17318565 cyclin E2 [Homo sapiens] Length = 404 Score = 822 bits (2124), Expect = 0.0 Identities = 404/404 (100%), Positives = 404/404 (100%) Query: 1 MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDVKKRREEVTKKHQYEIRNCWPP 60 MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDVKKRREEVTKKHQYEIRNCWPP Sbjct: 1 MSRRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDVKKRREEVTKKHQYEIRNCWPP 60 Query: 61 VLSGGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWGCSKEVWLNMLKK 120 VLSGGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWGCSKEVWLNMLKK Sbjct: 61 VLSGGISPCIIIETPHKEIGTSDFSRFTNYRFKNLFINPSPLPDLSWGCSKEVWLNMLKK 120 Query: 121 ESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDI 180 ESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDI Sbjct: 121 ESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDI 180 Query: 181 NKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCP 240 NKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCP Sbjct: 181 NKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCP 240 Query: 241 VTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAA 300 VTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAA Sbjct: 241 VTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAA 300 Query: 301 LCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPMEDRHNIQTH 360 LCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPMEDRHNIQTH Sbjct: 301 LCHFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPMEDRHNIQTH 360 Query: 361 TNYLAMLEEVNYINTFRKGGQLSPVCNGGIMTPPKSTEKPPGKH 404 TNYLAMLEEVNYINTFRKGGQLSPVCNGGIMTPPKSTEKPPGKH Sbjct: 361 TNYLAMLEEVNYINTFRKGGQLSPVCNGGIMTPPKSTEKPPGKH 404 >gi|17318559 cyclin E1 isoform 1 [Homo sapiens] Length = 410 Score = 364 bits (935), Expect = e-101 Identities = 185/335 (55%), Positives = 235/335 (70%), Gaps = 6/335 (1%) Query: 68 PCIIIETPHKEIGTSDFSRFTNYRFKNLFINPS---PLPDLSWGCSKEVWLNMLKKESRY 124 PC +I TP KE D + N K I PS PLP LSW +EVW ML KE Y Sbjct: 71 PCSLIPTPDKE---DDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTY 127 Query: 125 VHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNM 184 + D+HF H L+P+MR+ILLDWL+EVCEVY LHRETFYLAQDFFDR+M TQ+++ K + Sbjct: 128 LRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTL 187 Query: 185 LQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTII 244 LQLIGI+SLFIA+KLEEIY PKL +FAYVTDGACS ++IL MEL+I+KALKW L P+TI+ Sbjct: 188 LQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIV 247 Query: 245 SWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAALCHF 304 SWLN+++QV L D +VLLPQY Q+ FIQIA+LLDLC+L +D LEF Y IL A+AL HF Sbjct: 248 SWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHF 307 Query: 305 TSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPMEDRHNIQTHTNYL 364 +S E+++K SG +W I CV WMVPF V++ T KLK F+ + ED HNIQTH + L Sbjct: 308 SSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSL 367 Query: 365 AMLEEVNYINTFRKGGQLSPVCNGGIMTPPKSTEK 399 +L++ + G++TPP+S +K Sbjct: 368 DLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKK 402 >gi|17318561 cyclin E1 isoform 2 [Homo sapiens] Length = 395 Score = 364 bits (935), Expect = e-101 Identities = 185/335 (55%), Positives = 235/335 (70%), Gaps = 6/335 (1%) Query: 68 PCIIIETPHKEIGTSDFSRFTNYRFKNLFINPS---PLPDLSWGCSKEVWLNMLKKESRY 124 PC +I TP KE D + N K I PS PLP LSW +EVW ML KE Y Sbjct: 56 PCSLIPTPDKE---DDDRVYPNSTCKPRIIAPSRGSPLPVLSWANREEVWKIMLNKEKTY 112 Query: 125 VHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNM 184 + D+HF H L+P+MR+ILLDWL+EVCEVY LHRETFYLAQDFFDR+M TQ+++ K + Sbjct: 113 LRDQHFLEQHPLLQPKMRAILLDWLMEVCEVYKLHRETFYLAQDFFDRYMATQENVVKTL 172 Query: 185 LQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTII 244 LQLIGI+SLFIA+KLEEIY PKL +FAYVTDGACS ++IL MEL+I+KALKW L P+TI+ Sbjct: 173 LQLIGISSLFIAAKLEEIYPPKLHQFAYVTDGACSGDEILTMELMIMKALKWRLSPLTIV 232 Query: 245 SWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAALCHF 304 SWLN+++QV L D +VLLPQY Q+ FIQIA+LLDLC+L +D LEF Y IL A+AL HF Sbjct: 233 SWLNVYMQVAYLNDLHEVLLPQYPQQIFIQIAELLDLCVLDVDCLEFPYGILAASALYHF 292 Query: 305 TSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPVKLKTFKKIPMEDRHNIQTHTNYL 364 +S E+++K SG +W I CV WMVPF V++ T KLK F+ + ED HNIQTH + L Sbjct: 293 SSSELMQKVSGYQWCDIENCVKWMVPFAMVIRETGSSKLKHFRGVADEDAHNIQTHRDSL 352 Query: 365 AMLEEVNYINTFRKGGQLSPVCNGGIMTPPKSTEK 399 +L++ + G++TPP+S +K Sbjct: 353 DLLDKARAKKAMLSEQNRASPLPSGLLTPPQSGKK 387 >gi|161377472 cyclin A1 isoform c [Homo sapiens] Length = 421 Score = 103 bits (256), Expect = 4e-22 Identities = 54/143 (37%), Positives = 88/143 (61%), Gaps = 1/143 (0%) Query: 110 SKEVWLNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDF 169 ++E++ + + E R+ H+ D+ MR+IL+DWL+EV E Y L ET YLA +F Sbjct: 168 AEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 227 Query: 170 FDRFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELI 229 DRF L+ + + LQL+G ++ +ASK EEIY P++ EF Y+TD ++ +L+ME + Sbjct: 228 LDRF-LSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHL 286 Query: 230 ILKALKWELCPVTIISWLNLFLQ 252 +LK L ++L T +L +L+ Sbjct: 287 LLKVLAFDLTVPTTNQFLLQYLR 309 >gi|161377470 cyclin A1 isoform c [Homo sapiens] Length = 421 Score = 103 bits (256), Expect = 4e-22 Identities = 54/143 (37%), Positives = 88/143 (61%), Gaps = 1/143 (0%) Query: 110 SKEVWLNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDF 169 ++E++ + + E R+ H+ D+ MR+IL+DWL+EV E Y L ET YLA +F Sbjct: 168 AEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 227 Query: 170 FDRFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELI 229 DRF L+ + + LQL+G ++ +ASK EEIY P++ EF Y+TD ++ +L+ME + Sbjct: 228 LDRF-LSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHL 286 Query: 230 ILKALKWELCPVTIISWLNLFLQ 252 +LK L ++L T +L +L+ Sbjct: 287 LLKVLAFDLTVPTTNQFLLQYLR 309 >gi|161377468 cyclin A1 isoform b [Homo sapiens] Length = 464 Score = 103 bits (256), Expect = 4e-22 Identities = 54/143 (37%), Positives = 88/143 (61%), Gaps = 1/143 (0%) Query: 110 SKEVWLNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDF 169 ++E++ + + E R+ H+ D+ MR+IL+DWL+EV E Y L ET YLA +F Sbjct: 211 AEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 270 Query: 170 FDRFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELI 229 DRF L+ + + LQL+G ++ +ASK EEIY P++ EF Y+TD ++ +L+ME + Sbjct: 271 LDRF-LSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHL 329 Query: 230 ILKALKWELCPVTIISWLNLFLQ 252 +LK L ++L T +L +L+ Sbjct: 330 LLKVLAFDLTVPTTNQFLLQYLR 352 >gi|4502611 cyclin A1 isoform a [Homo sapiens] Length = 465 Score = 103 bits (256), Expect = 4e-22 Identities = 54/143 (37%), Positives = 88/143 (61%), Gaps = 1/143 (0%) Query: 110 SKEVWLNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDF 169 ++E++ + + E R+ H+ D+ MR+IL+DWL+EV E Y L ET YLA +F Sbjct: 212 AEEIYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNF 271 Query: 170 FDRFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELI 229 DRF L+ + + LQL+G ++ +ASK EEIY P++ EF Y+TD ++ +L+ME + Sbjct: 272 LDRF-LSCMSVLRGKLQLVGTAAMLLASKYEEIYPPEVDEFVYITDDTYTKRQLLKMEHL 330 Query: 230 ILKALKWELCPVTIISWLNLFLQ 252 +LK L ++L T +L +L+ Sbjct: 331 LLKVLAFDLTVPTTNQFLLQYLR 353 >gi|4502613 cyclin A [Homo sapiens] Length = 432 Score = 100 bits (248), Expect = 3e-21 Identities = 48/115 (41%), Positives = 76/115 (66%), Gaps = 1/115 (0%) Query: 136 DLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFI 195 D+ MR+IL+DWL+EV E Y L ET +LA ++ DRF L+ + + LQL+G ++ + Sbjct: 205 DITNSMRAILVDWLVEVGEEYKLQNETLHLAVNYIDRF-LSSMSVLRGKLQLVGTAAMLL 263 Query: 196 ASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLF 250 ASK EEIY P++ EF Y+TD +++ +LRME ++LK L ++L T+ +L + Sbjct: 264 ASKFEEIYPPEVAEFVYITDDTYTKKQVLRMEHLVLKVLTFDLAAPTVNQFLTQY 318 >gi|4757930 cyclin B2 [Homo sapiens] Length = 398 Score = 99.0 bits (245), Expect = 7e-21 Identities = 63/188 (33%), Positives = 101/188 (53%), Gaps = 21/188 (11%) Query: 124 YVHDKHFEVLHS---------DLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFM 174 Y + + EVL S D+ +MR+IL+DWL++V + L +ET Y+ DRF+ Sbjct: 139 YQYLRQLEVLQSINPHFLDGRDINGRMRAILVDWLVQVHSKFRLLQETLYMCVGIMDRFL 198 Query: 175 LTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKAL 234 Q +++ LQL+GIT+L +ASK EE+++P +++F Y+TD A + I ME +ILK L Sbjct: 199 QVQP-VSRKKLQLVGITALLLASKYEEMFSPNIEDFVYITDNAYTSSQIREMETLILKEL 257 Query: 235 KWELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYR 294 K+E L L + L+ A K Q T + L++L ++ D + + Sbjct: 258 KFE---------LGRPLPLHFLRRASKAGEVDVEQHTLAK--YLMELTLIDYDMVHYHPS 306 Query: 295 ILTAAALC 302 + AAA C Sbjct: 307 KVAAAASC 314 >gi|14327896 cyclin B1 [Homo sapiens] Length = 433 Score = 96.7 bits (239), Expect = 3e-20 Identities = 63/183 (34%), Positives = 101/183 (55%), Gaps = 14/183 (7%) Query: 120 KESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKD 179 +E + V K+ +L ++ MR+IL+DWL++V + L +ET Y+ DRFM Sbjct: 182 EEEQAVRPKY--LLGREVTGNMRAILIDWLVQVQMKFRLLQETMYMTVSIIDRFM-QNNC 238 Query: 180 INKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELC 239 + K MLQL+G+T++FIASK EE+Y P++ +FA+VTD ++ I +ME+ IL+AL + Sbjct: 239 VPKKMLQLVGVTAMFIASKYEEMYPPEIGDFAFVTDNTYTKHQIRQMEMKILRALNF--- 295 Query: 240 PVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAA 299 L L + L+ A K+ Q T + L++L +L D + F + A Sbjct: 296 ------GLGRPLPLHFLRRASKIGEVDVEQHTLAK--YLMELTMLDYDMVHFPPSQIAAG 347 Query: 300 ALC 302 A C Sbjct: 348 AFC 350 >gi|16950655 cyclin D1 [Homo sapiens] Length = 295 Score = 93.2 bits (230), Expect = 4e-19 Identities = 52/160 (32%), Positives = 90/160 (56%), Gaps = 3/160 (1%) Query: 117 MLKKESRYVHD-KHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFML 175 MLK E +F+ + ++ P MR I+ W+LEVCE E F LA ++ DRF L Sbjct: 31 MLKAEETCAPSVSYFKCVQKEVLPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLDRF-L 89 Query: 176 TQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALK 235 + + + K+ LQL+G T +F+ASK++E ++ TD + E++L+MEL+++ LK Sbjct: 90 SLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPEELLQMELLLVNKLK 149 Query: 236 WELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQI 275 W L +T ++ FL + K ++ +++Q TF+ + Sbjct: 150 WNLAAMTPHDFIEHFLSKMPEAEENKQIIRKHAQ-TFVAL 188 >gi|4502617 cyclin D2 [Homo sapiens] Length = 289 Score = 88.6 bits (218), Expect = 9e-18 Identities = 53/161 (32%), Positives = 86/161 (53%), Gaps = 3/161 (1%) Query: 116 NMLKKESRYVHD-KHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFM 174 N+L E RY+ +F+ + D++P MR ++ W+LEVCE E F LA ++ DRF Sbjct: 29 NLLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRF- 87 Query: 175 LTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKAL 234 L K+ LQL+G +F+ASKL+E ++ TD + +++L EL++L L Sbjct: 88 LAGVPTPKSHLQLLGAVCMFLASKLKETSPLTAEKLCIYTDNSIKPQELLEWELVVLGKL 147 Query: 235 KWELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQI 275 KW L VT ++ L+ + K+ L + +TFI + Sbjct: 148 KWNLAAVTPHDFIEHILR-KLPQQREKLSLIRKHAQTFIAL 187 >gi|4502619 cyclin D3 isoform 2 [Homo sapiens] Length = 292 Score = 86.3 bits (212), Expect = 5e-17 Identities = 64/233 (27%), Positives = 111/233 (47%), Gaps = 9/233 (3%) Query: 99 PSPLPDLSWGCSKEVWLNMLKKESRYV-HDKHFEVLHSDLEPQMRSILLDWLLEVCEVYT 157 P PD + V ++L+ E RYV +F+ + +++P MR +L W+LEVCE Sbjct: 13 PRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLAYWMLEVCEEQR 72 Query: 158 LHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGA 217 E F LA ++ DR+ L+ K LQL+G + +ASKL E +++ TD A Sbjct: 73 CEEEVFPLAMNYLDRY-LSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHA 131 Query: 218 CSEEDILRMELIILKALKWELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIA- 276 S + E+++L LKW+L V +L L +L + L+ +++Q TF+ + Sbjct: 132 VSPRQLRDWEVLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQ-TFLALCA 190 Query: 277 -----QLLDLCILAIDSLEFQYRILTAAALCHFTSIEVVKKASGLEWDSISEC 324 + ++A S+ + L A ++ E++ +G E D + C Sbjct: 191 TDYTFAMYPPSMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRAC 243 >gi|90669307 cyclin B3 isoform 3 [Homo sapiens] Length = 1395 Score = 77.4 bits (189), Expect = 2e-14 Identities = 41/129 (31%), Positives = 75/129 (58%), Gaps = 2/129 (1%) Query: 110 SKEVWLNMLKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDF 169 +KE++ M ++E +++ + ++ MR+IL+DWL+EV + + ET YLA Sbjct: 1130 AKEIFSYMKEREEQFILTDYMN-RQIEITSDMRAILVDWLVEVQVSFEMTHETLYLAVKL 1188 Query: 170 FDRFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELI 229 D +++ + K+ LQL+G T+ IA+K EE +P++ +F Y+ D ++L ME+ Sbjct: 1189 VDLYLM-KAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICDDNYQRSEVLSMEIN 1247 Query: 230 ILKALKWEL 238 IL LK ++ Sbjct: 1248 ILNVLKCDI 1256 >gi|5802992 cyclin I [Homo sapiens] Length = 377 Score = 73.9 bits (180), Expect = 2e-13 Identities = 63/224 (28%), Positives = 112/224 (50%), Gaps = 20/224 (8%) Query: 134 HSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSL 193 + ++ P R ++ WL ++ + L+ ETF LA DRF+ T K + L I I+ Sbjct: 37 NQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVK-AHPKYLSCIAISCF 95 Query: 194 FIASKL--EEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLFL 251 F+A+K E+ P L+ A + CS +ILRME IIL L W+L T + +L++F Sbjct: 96 FLAAKTVEEDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFLHIFH 155 Query: 252 QVDALKDAPKVL--LPQY--SQETFIQIAQLLDLCILAIDSLEFQYRILTAAALC----- 302 + A+ P++L LP+ SQ + QLL C+ L+F+ +L A + Sbjct: 156 AI-AVSTRPQLLFSLPKLSPSQHLAVLTKQLLH-CMACNQLLQFRGSMLALAMVSLEMEK 213 Query: 303 -----HFTSIEVVKKASGLEWDSISECVDWMVPFVNVVKSTSPV 341 +IE+++KA ++ + C + + ++ ++S+ P+ Sbjct: 214 LIPDWLSLTIELLQKAQ-MDSSQLIHCRELVAHHLSTLQSSLPL 256 >gi|153791755 cyclin domain containing [Homo sapiens] Length = 350 Score = 62.0 bits (149), Expect = 9e-10 Identities = 39/132 (29%), Positives = 65/132 (49%), Gaps = 1/132 (0%) Query: 119 KKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQK 178 K + + H + + + R LL WL+ V + L E+ L + DRF LT Sbjct: 110 KAQESHFHPREALARQPQVTAESRCKLLSWLIPVHRQFGLSFESLCLTVNTLDRF-LTTT 168 Query: 179 DINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWEL 238 + + QL+G+TSL IA K E++ P++++ + GA S + + +E I+L L + L Sbjct: 169 PVAADCFQLLGVTSLLIACKQVEVHPPRVKQLLALCCGAFSRQQLCNLECIVLHKLHFTL 228 Query: 239 CPVTIISWLNLF 250 TI +L F Sbjct: 229 GAPTISFFLEHF 240 >gi|242247025 cyclin N-terminal domain containing 2 isoform 2 [Homo sapiens] Length = 307 Score = 61.2 bits (147), Expect = 2e-09 Identities = 33/100 (33%), Positives = 57/100 (57%), Gaps = 1/100 (1%) Query: 139 PQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASK 198 P+MR++++DWL++V E L +T YLA D ++ + + + LQL+G+ LF+A K Sbjct: 105 PEMRALVVDWLVQVHEYLGLAGDTLYLAVHLLDSYLSAGR-VRLHRLQLLGVACLFVACK 163 Query: 199 LEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWEL 238 +EE P+ ++ + S ++LR E IL L + L Sbjct: 164 MEECVLPEPAFLCLLSADSFSRAELLRAERRILSRLDFRL 203 >gi|89886237 cyclin I family, member 2 [Homo sapiens] Length = 369 Score = 58.5 bits (140), Expect = 1e-08 Identities = 46/150 (30%), Positives = 76/150 (50%), Gaps = 7/150 (4%) Query: 148 WLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKL--EEIYAP 205 WLL + + + TF LA F R +++ K + + L ITSL +A+K+ EE + P Sbjct: 156 WLLRLQNTFYFSQSTFNLALTIFGRLLISVK-VKEKYLHCATITSLRLAAKVNEEEEFIP 214 Query: 206 KLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLFLQVDALKDAPKV--L 263 ++++F S ++LRMEL IL L W+L T + +L +F + L P V L Sbjct: 215 QVKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFLTIFHALVVL-SWPHVLEL 273 Query: 264 LPQYSQETFI-QIAQLLDLCILAIDSLEFQ 292 LPQ + + + + L C+ L+F+ Sbjct: 274 LPQRNPSLHVASLTRQLQHCMAGHQLLQFK 303 >gi|16306525 cyclin B3 isoform 1 [Homo sapiens] Length = 291 Score = 55.8 bits (133), Expect = 7e-08 Identities = 28/83 (33%), Positives = 48/83 (57%), Gaps = 1/83 (1%) Query: 156 YTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTD 215 + + ET YLA D +++ + K+ LQL+G T+ IA+K EE +P++ +F Y+ D Sbjct: 71 FEMTHETLYLAVKLVDLYLM-KAVCKKDKLQLLGATAFMIAAKFEEHNSPRVDDFVYICD 129 Query: 216 GACSEEDILRMELIILKALKWEL 238 ++L ME+ IL LK ++ Sbjct: 130 DNYQRSEVLSMEINILNVLKCDI 152 >gi|4757936 cyclin G2 [Homo sapiens] Length = 344 Score = 53.5 bits (127), Expect = 3e-07 Identities = 33/114 (28%), Positives = 59/114 (51%), Gaps = 3/114 (2%) Query: 139 PQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASK 198 P +R+ ++ L + + ETF LA + DRF+ K + L IG+ S +A++ Sbjct: 53 PGLRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMK-VKPKHLSCIGVCSFLLAAR 111 Query: 199 L--EEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLF 250 + E+ P + ++ C+ DI RME II + L +EL T +++L+L+ Sbjct: 112 IVEEDCNIPSTHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLY 165 >gi|118572588 cyclin F [Homo sapiens] Length = 786 Score = 52.0 bits (123), Expect = 1e-06 Identities = 35/134 (26%), Positives = 67/134 (50%), Gaps = 1/134 (0%) Query: 118 LKKESRYVHDKHFEVLHSDLEPQMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQ 177 L + S+ V + + L MR IL+DWL+EV + +L + DR+ L + Sbjct: 286 LFQASQAVSKQQVFSVQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRY-LRR 344 Query: 178 KDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWE 237 + + + LQL+GI + I ++ ++E ++TD ED++RM I+ AL+ + Sbjct: 345 RLVPRYRLQLLGIACMVICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGK 404 Query: 238 LCPVTIISWLNLFL 251 + T++ + + L Sbjct: 405 IRVPTVVDYKEVLL 418 >gi|197276674 cyclin J isoform 1 [Homo sapiens] Length = 383 Score = 49.3 bits (116), Expect = 6e-06 Identities = 49/210 (23%), Positives = 93/210 (44%), Gaps = 29/210 (13%) Query: 141 MRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKLE 200 +R D + V +TL +LA D FM + DI+ L L+ ++ L +ASK E Sbjct: 39 LRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFM-DRYDISIQQLHLVALSCLLLASKFE 97 Query: 201 EIY--APKLQEFAYV-----TDGACSEEDILRMELIILKALKWELCPVTIISWLNLFL-- 251 E PKL++ + + +++++L MEL++L+ +W LC T ++ +L Sbjct: 98 EKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSE 157 Query: 252 ---QVDALKDAPKVLLPQYSQETFIQIAQLLD--LCILAIDSLEFQYRILTAAALCHFTS 306 + D P + L ++T + +A+ D L + D Y AA C +S Sbjct: 158 AVHETDLHDGWPMICL----EKTKLYMAKYADYFLEVSLQDYAFLNYAPSLVAAACVASS 213 Query: 307 IEVVK----------KASGLEWDSISECVD 326 +++ + + WD + +C++ Sbjct: 214 RIILRLSPTWPTRLHRLTAYSWDFLVQCIE 243 >gi|209862835 cyclin D3 isoform 1 [Homo sapiens] Length = 211 Score = 48.1 bits (113), Expect = 1e-05 Identities = 40/163 (24%), Positives = 75/163 (46%), Gaps = 8/163 (4%) Query: 168 DFFDRFMLTQKDINKNMLQLIGITSLFIASKLEEIYAPKLQEFAYVTDGACSEEDILRME 227 ++ DR+ L+ K LQL+G + +ASKL E +++ TD A S + E Sbjct: 2 NYLDRY-LSCVPTRKAQLQLLGAVCMLLASKLRETTPLTIEKLCIYTDHAVSPRQLRDWE 60 Query: 228 LIILKALKWELCPVTIISWLNLFLQVDALKDAPKVLLPQYSQETFIQIA------QLLDL 281 +++L LKW+L V +L L +L + L+ +++Q TF+ + + Sbjct: 61 VLVLGKLKWDLAAVIAHDFLAFILHRLSLPRDRQALVKKHAQ-TFLALCATDYTFAMYPP 119 Query: 282 CILAIDSLEFQYRILTAAALCHFTSIEVVKKASGLEWDSISEC 324 ++A S+ + L A ++ E++ +G E D + C Sbjct: 120 SMIATGSIGAAVQGLGACSMSGDELTELLAGITGTEVDCLRAC 162 >gi|40254889 cyclin J isoform 2 [Homo sapiens] Length = 372 Score = 47.4 bits (111), Expect = 2e-05 Identities = 48/208 (23%), Positives = 91/208 (43%), Gaps = 36/208 (17%) Query: 141 MRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKLE 200 +R D + V +TL +LA D FM + DI+ L L+ ++ L +ASK E Sbjct: 39 LRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFM-DRYDISIQQLHLVALSCLLLASKFE 97 Query: 201 EIY--APKLQEFAYV-----TDGACSEEDILRMELIILKALKWELCPVTIISWLNLFL-- 251 E PKL++ + + +++++L MEL++L+ +W LC T ++ +L Sbjct: 98 EKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYLSE 157 Query: 252 ---QVDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAALCHFTSIE 308 + D P + L ++T + +A+ D F L AA C +S Sbjct: 158 AVHETDLHDGWPMICL----EKTKLYMAKYADY---------FLEVSLQVAAACVASSRI 204 Query: 309 VVK----------KASGLEWDSISECVD 326 +++ + + WD + +C++ Sbjct: 205 ILRLSPTWPTRLHRLTAYSWDFLVQCIE 232 >gi|40805832 cyclin G1 [Homo sapiens] Length = 295 Score = 46.6 bits (109), Expect = 4e-05 Identities = 29/113 (25%), Positives = 56/113 (49%), Gaps = 3/113 (2%) Query: 140 QMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKL 199 ++R + LL + + + ETF LA + DRF+ K + L +G++ ++A K Sbjct: 50 RLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMK-VQPKHLGCVGLSCFYLAVKS 108 Query: 200 --EEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLF 250 EE P + ++ + D++RME I+L+ + W++ T +L L+ Sbjct: 109 IEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLY 161 >gi|4757934 cyclin G1 [Homo sapiens] Length = 295 Score = 46.6 bits (109), Expect = 4e-05 Identities = 29/113 (25%), Positives = 56/113 (49%), Gaps = 3/113 (2%) Query: 140 QMRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKL 199 ++R + LL + + + ETF LA + DRF+ K + L +G++ ++A K Sbjct: 50 RLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMK-VQPKHLGCVGLSCFYLAVKS 108 Query: 200 --EEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLF 250 EE P + ++ + D++RME I+L+ + W++ T +L L+ Sbjct: 109 IEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLY 161 >gi|197276676 cyclin J isoform 3 [Homo sapiens] Length = 371 Score = 46.6 bits (109), Expect = 4e-05 Identities = 33/118 (27%), Positives = 59/118 (50%), Gaps = 8/118 (6%) Query: 141 MRSILLDWLLEVCEVYTLHRETFYLAQDFFDRFMLTQKDINKNMLQLIGITSLFIASKLE 200 +R D + V +TL +LA D FM + DI+ L L+ ++ L +ASK E Sbjct: 39 LRRYFADLIAIVSNRFTLCPSARHLAVYLLDLFM-DRYDISIQQLHLVALSCLLLASKFE 97 Query: 201 EIY--APKLQEFAYV-----TDGACSEEDILRMELIILKALKWELCPVTIISWLNLFL 251 E PKL++ + + +++++L MEL++L+ +W LC T ++ +L Sbjct: 98 EKEDSVPKLEQLNSLGCMTNMNLVLTKQNLLHMELLLLETFQWNLCLPTAAHFIEYYL 155 >gi|94680985 cyclin J-like [Homo sapiens] Length = 435 Score = 35.8 bits (81), Expect = 0.071 Identities = 37/169 (21%), Positives = 74/169 (43%), Gaps = 20/169 (11%) Query: 198 KLEEIYAPKLQEFAYVTDGACSEEDILRMELIILKALKWELCPVTIISWLNLFL-----Q 252 KLE+I + ++ T +++++L EL++L+A W LC T +L+ +L Q Sbjct: 153 KLEQINSTRILSSQNFT---LTKKELLSTELLLLEAFSWNLCLPTPAHFLDYYLLASVSQ 209 Query: 253 VDALKDAPKVLLPQYSQETFIQIAQLLDLCILAIDSLEFQYRILTAAALCHFTS------ 306 D P+ ++E + A L + D + ++++ AA C S Sbjct: 210 KDHHCHTWPTTCPRKTKECLKEYAHYF-LEVTLQDHIFYKFQPSVVAAACVGASRICLQL 268 Query: 307 ----IEVVKKASGLEWDSISECVD-WMVPFVNVVKSTSPVKLKTFKKIP 350 +++ S + +S C++ +V + NV+K VK + +P Sbjct: 269 SPYWTRDLQRISSYSLEHLSTCIEILLVVYDNVLKDAVAVKSQALAMVP 317 >gi|209915553 cyclin D3 isoform 3 [Homo sapiens] Length = 220 Score = 35.0 bits (79), Expect = 0.12 Identities = 22/69 (31%), Positives = 36/69 (52%), Gaps = 1/69 (1%) Query: 99 PSPLPDLSWGCSKEVWLNMLKKESRYV-HDKHFEVLHSDLEPQMRSILLDWLLEVCEVYT 157 P PD + V ++L+ E RYV +F+ + +++P MR +L W+LE EV Sbjct: 13 PRAGPDPRLLGDQRVLQSLLRLEERYVPRASYFQCVQREIKPHMRKMLAYWMLEDWEVLV 72 Query: 158 LHRETFYLA 166 L + + LA Sbjct: 73 LGKLKWDLA 81 >gi|187173292 troponin T1, skeletal, slow isoform c [Homo sapiens] Length = 251 Score = 32.7 bits (73), Expect = 0.60 Identities = 18/47 (38%), Positives = 29/47 (61%), Gaps = 2/47 (4%) Query: 3 RRSSRLQAKQQPQPSQTESPQEAQIIQAKKRKTTQDVKKRREEVTKK 49 RRS R A+QQ ++ E ++A++ + K RK ++ KKR E+ KK Sbjct: 95 RRSER--AEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKK 139 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.135 0.410 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,892,732 Number of Sequences: 37866 Number of extensions: 691502 Number of successful extensions: 2357 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 32 Number of HSP's successfully gapped in prelim test: 8 Number of HSP's that attempted gapping in prelim test: 2301 Number of HSP's gapped (non-prelim): 42 length of query: 404 length of database: 18,247,518 effective HSP length: 105 effective length of query: 299 effective length of database: 14,271,588 effective search space: 4267204812 effective search space used: 4267204812 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.