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Search of human proteins with 17298690
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|17298690 poly-U binding splicing factor 60KDa isoform b
[Homo sapiens]
(542 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo... 1056 0.0
gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo... 1046 0.0
gi|209862867 poly-U binding splicing factor 60KDa isoform c [Hom... 962 0.0
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 102 9e-22
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 102 9e-22
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 102 9e-22
gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens] 100 3e-21
gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens] 100 3e-21
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 94 2e-19
gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo s... 94 4e-19
gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens] 92 9e-19
gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens] 92 9e-19
gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens] 92 9e-19
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 92 2e-18
gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Hom... 88 2e-17
gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo... 88 2e-17
gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo s... 86 9e-17
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 86 9e-17
gi|188219593 TIA1 protein isoform 1 [Homo sapiens] 85 2e-16
gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens] 83 6e-16
gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens] 83 6e-16
gi|188219591 TIA1 protein isoform 2 [Homo sapiens] 83 7e-16
gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens] 78 2e-14
gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo sa... 75 2e-13
gi|20373175 musashi 2 isoform a [Homo sapiens] 75 2e-13
gi|25121993 musashi 2 isoform b [Homo sapiens] 75 2e-13
gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo s... 75 2e-13
gi|187761299 bruno-like 4, RNA binding protein isoform 2 [Homo s... 75 2e-13
gi|224549005 RNA binding motif protein 17 [Homo sapiens] 74 3e-13
gi|14249678 RNA binding motif protein 17 [Homo sapiens] 74 3e-13
>gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo
sapiens]
Length = 542
Score = 1056 bits (2732), Expect = 0.0
Identities = 542/542 (100%), Positives = 542/542 (100%)
Query: 1 MATATIALQVNGQQGGGSEPAAAAAVVAAGDKWKPPQGTDSIKMENGQSTAAKLGLPPLT 60
MATATIALQVNGQQGGGSEPAAAAAVVAAGDKWKPPQGTDSIKMENGQSTAAKLGLPPLT
Sbjct: 1 MATATIALQVNGQQGGGSEPAAAAAVVAAGDKWKPPQGTDSIKMENGQSTAAKLGLPPLT 60
Query: 61 PEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAQRQRALAIMCRVYVGSIY 120
PEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAQRQRALAIMCRVYVGSIY
Sbjct: 61 PEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAQRQRALAIMCRVYVGSIY 120
Query: 121 YELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGG 180
YELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGG
Sbjct: 121 YELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGG 180
Query: 181 RNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTL 240
RNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTL
Sbjct: 181 RNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTL 240
Query: 241 ARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGG 300
ARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGG
Sbjct: 241 ARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGG 300
Query: 301 LPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAP 360
LPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAP
Sbjct: 301 LPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAP 360
Query: 361 GVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQ 420
GVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQ
Sbjct: 361 GVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQ 420
Query: 421 EHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVI 480
EHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVI
Sbjct: 421 EHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVI 480
Query: 481 IYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDL 540
IYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDL
Sbjct: 481 IYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDL 540
Query: 541 SA 542
SA
Sbjct: 541 SA 542
>gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo
sapiens]
Length = 559
Score = 1046 bits (2704), Expect = 0.0
Identities = 542/559 (96%), Positives = 542/559 (96%), Gaps = 17/559 (3%)
Query: 1 MATATIALQVNGQQGGGSEPAAAAAVVAAGDKWKPPQGTDSIKMENGQSTAAKLGLPPLT 60
MATATIALQVNGQQGGGSEPAAAAAVVAAGDKWKPPQGTDSIKMENGQSTAAKLGLPPLT
Sbjct: 1 MATATIALQVNGQQGGGSEPAAAAAVVAAGDKWKPPQGTDSIKMENGQSTAAKLGLPPLT 60
Query: 61 PEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAA-----------------Q 103
PEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAA Q
Sbjct: 61 PEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAVTMGFGDPLSPLQSMAAQ 120
Query: 104 RQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVP 163
RQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVP
Sbjct: 121 RQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVP 180
Query: 164 EAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDD 223
EAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDD
Sbjct: 181 EAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDD 240
Query: 224 DIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVG 283
DIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVG
Sbjct: 241 DIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVG 300
Query: 284 KAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGLVSPALTL 343
KAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGLVSPALTL
Sbjct: 301 KAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGLVSPALTL 360
Query: 344 AQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKE 403
AQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKE
Sbjct: 361 AQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKE 420
Query: 404 EEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLE 463
EEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLE
Sbjct: 421 EEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTVMVLRNMVDPKDIDDDLE 480
Query: 464 GEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGR 523
GEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGR
Sbjct: 481 GEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGR 540
Query: 524 KVVAEVYDQERFDNSDLSA 542
KVVAEVYDQERFDNSDLSA
Sbjct: 541 KVVAEVYDQERFDNSDLSA 559
>gi|209862867 poly-U binding splicing factor 60KDa isoform c [Homo
sapiens]
Length = 516
Score = 962 bits (2486), Expect = 0.0
Identities = 499/516 (96%), Positives = 499/516 (96%), Gaps = 17/516 (3%)
Query: 44 MENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAA- 102
MENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAA
Sbjct: 1 MENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAV 60
Query: 103 ----------------QRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWD 146
QRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWD
Sbjct: 61 TMGFGDPLSPLQSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWD 120
Query: 147 SVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEAR 206
SVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEAR
Sbjct: 121 SVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEAR 180
Query: 207 AFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDA 266
AFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDA
Sbjct: 181 AFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDA 240
Query: 267 VSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAA 326
VSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAA
Sbjct: 241 VSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAA 300
Query: 327 VLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPI 386
VLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPI
Sbjct: 301 VLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPI 360
Query: 387 LASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTV 446
LASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTV
Sbjct: 361 LASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISGSSARHMVMQKLLRKQESTV 420
Query: 447 MVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIAS 506
MVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIAS
Sbjct: 421 MVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIAS 480
Query: 507 ETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA 542
ETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA
Sbjct: 481 ETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLSA 516
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 102 bits (254), Expect = 9e-22
Identities = 56/172 (32%), Positives = 96/172 (55%), Gaps = 6/172 (3%)
Query: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
V++ ++ + + F+ FG I S + D KG+AFV +E EAA A+E+M
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEKM 158
Query: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 233
N ++L R + VGR + + + +L +A+ F +Y+ + +++ D+ +K +F FG
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREA---ELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFG 215
Query: 234 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 285
K S + RDP GK KG+GF+ YEK + + AV MN ++ G+ + VG+A
Sbjct: 216 KTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRA 266
Score = 79.3 bits (194), Expect = 8e-15
Identities = 45/174 (25%), Positives = 88/174 (50%), Gaps = 11/174 (6%)
Query: 111 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 170
M +YVG ++ ++ E + + F+P GP+ SI + D +T + G+A+V ++ P A+ AL
Sbjct: 10 MASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
Query: 171 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 230
+ MN ++ G+ I++ Q P + +++ ++ + + + + F
Sbjct: 70 DTMNFDVIKGKPIRI----MWSQRDPSL-----RKSGVGNVFIKNLDKSIDNKALYDTFS 120
Query: 231 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 284
AFG I SC + D KGY F+ +E +++ A+ MN L + + VG+
Sbjct: 121 AFGNILSCKVVCDENGS--KGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGR 172
Score = 78.2 bits (191), Expect = 2e-14
Identities = 64/239 (26%), Positives = 115/239 (48%), Gaps = 31/239 (12%)
Query: 62 EQQEALQKA--KKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAQRQRALAIMCRVYVGSI 119
E QEA KA K M + + V V + + ++++ ++ A+ + VY+ +
Sbjct: 146 ETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREA---ELGAKAKE----FTNVYIKNF 198
Query: 120 YYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLG 179
E+ ++++++ F+ FG S+ + D K KGF FV YE E A A+E+MN +
Sbjct: 199 GEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEMNGKEIS 257
Query: 180 GRNIKVGRPSNIGQAQPIIDQLAEEARAFNR-------------IYVASVHQDLSDDDIK 226
G+ I VGR AQ +++ AE R F + +Y+ ++ + D+ ++
Sbjct: 258 GKIIFVGR------AQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLR 311
Query: 227 SVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 285
F FG I S + + G+ KG+GF+ + + + AV+ MN +G + L V A
Sbjct: 312 KEFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALA 368
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 102 bits (254), Expect = 9e-22
Identities = 56/172 (32%), Positives = 96/172 (55%), Gaps = 6/172 (3%)
Query: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
V++ ++ + + F+ FG I S + D KG+AFV +E EAA A+E+M
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEKM 158
Query: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 233
N ++L R + VGR + + + +L +A+ F +Y+ + +++ D+ +K +F FG
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREA---ELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFG 215
Query: 234 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 285
K S + RDP GK KG+GF+ YEK + + AV MN ++ G+ + VG+A
Sbjct: 216 KTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRA 266
Score = 79.3 bits (194), Expect = 8e-15
Identities = 45/174 (25%), Positives = 88/174 (50%), Gaps = 11/174 (6%)
Query: 111 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 170
M +YVG ++ ++ E + + F+P GP+ SI + D +T + G+A+V ++ P A+ AL
Sbjct: 10 MASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
Query: 171 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 230
+ MN ++ G+ I++ Q P + +++ ++ + + + + F
Sbjct: 70 DTMNFDVIKGKPIRI----MWSQRDPSL-----RKSGVGNVFIKNLDKSIDNKALYDTFS 120
Query: 231 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 284
AFG I SC + D KGY F+ +E +++ A+ MN L + + VG+
Sbjct: 121 AFGNILSCKVVCDENGS--KGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGR 172
Score = 78.2 bits (191), Expect = 2e-14
Identities = 64/239 (26%), Positives = 115/239 (48%), Gaps = 31/239 (12%)
Query: 62 EQQEALQKA--KKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAQRQRALAIMCRVYVGSI 119
E QEA KA K M + + V V + + ++++ ++ A+ + VY+ +
Sbjct: 146 ETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREA---ELGAKAKE----FTNVYIKNF 198
Query: 120 YYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLG 179
E+ ++++++ F+ FG S+ + D K KGF FV YE E A A+E+MN +
Sbjct: 199 GEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEMNGKEIS 257
Query: 180 GRNIKVGRPSNIGQAQPIIDQLAEEARAFNR-------------IYVASVHQDLSDDDIK 226
G+ I VGR AQ +++ AE R F + +Y+ ++ + D+ ++
Sbjct: 258 GKIIFVGR------AQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLR 311
Query: 227 SVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 285
F FG I S + + G+ KG+GF+ + + + AV+ MN +G + L V A
Sbjct: 312 KEFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALA 368
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 102 bits (254), Expect = 9e-22
Identities = 56/172 (32%), Positives = 96/172 (55%), Gaps = 6/172 (3%)
Query: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
V++ ++ + + F+ FG I S + D KG+AFV +E EAA A+E+M
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYAFVHFETQEAADKAIEKM 158
Query: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 233
N ++L R + VGR + + + +L +A+ F +Y+ + +++ D+ +K +F FG
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREA---ELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFG 215
Query: 234 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 285
K S + RDP GK KG+GF+ YEK + + AV MN ++ G+ + VG+A
Sbjct: 216 KTLSVKVMRDPN-GKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRA 266
Score = 79.3 bits (194), Expect = 8e-15
Identities = 45/174 (25%), Positives = 88/174 (50%), Gaps = 11/174 (6%)
Query: 111 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 170
M +YVG ++ ++ E + + F+P GP+ SI + D +T + G+A+V ++ P A+ AL
Sbjct: 10 MASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
Query: 171 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 230
+ MN ++ G+ I++ Q P + +++ ++ + + + + F
Sbjct: 70 DTMNFDVIKGKPIRI----MWSQRDPSL-----RKSGVGNVFIKNLDKSIDNKALYDTFS 120
Query: 231 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 284
AFG I SC + D KGY F+ +E +++ A+ MN L + + VG+
Sbjct: 121 AFGNILSCKVVCDENGS--KGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGR 172
Score = 78.2 bits (191), Expect = 2e-14
Identities = 64/239 (26%), Positives = 115/239 (48%), Gaps = 31/239 (12%)
Query: 62 EQQEALQKA--KKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAQRQRALAIMCRVYVGSI 119
E QEA KA K M + + V V + + ++++ ++ A+ + VY+ +
Sbjct: 146 ETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREA---ELGAKAKE----FTNVYIKNF 198
Query: 120 YYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLG 179
E+ ++++++ F+ FG S+ + D K KGF FV YE E A A+E+MN +
Sbjct: 199 GEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEKHEDANKAVEEMNGKEIS 257
Query: 180 GRNIKVGRPSNIGQAQPIIDQLAEEARAFNR-------------IYVASVHQDLSDDDIK 226
G+ I VGR AQ +++ AE R F + +Y+ ++ + D+ ++
Sbjct: 258 GKIIFVGR------AQKKVERQAELKRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLR 311
Query: 227 SVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 285
F FG I S + + G+ KG+GF+ + + + AV+ MN +G + L V A
Sbjct: 312 KEFSPFGSITSAKVMLE--DGRSKGFGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALA 368
>gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens]
Length = 530
Score = 100 bits (250), Expect = 3e-21
Identities = 94/405 (23%), Positives = 173/405 (42%), Gaps = 75/405 (18%)
Query: 128 IRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGR 187
+ + F+ G ++ + M D + + KG A+VE+ + LA+ +LG I
Sbjct: 169 LEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQAS 228
Query: 188 PSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTG 247
+ +A + + L + + R+YV S+H ++++D ++ +FE FG+I+S L D TG
Sbjct: 229 QAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETG 288
Query: 248 KHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAV 307
+ KGYGFI + ++ ++ A+ +N F+L G+ ++VG +T T
Sbjct: 289 RSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGH--------VTERTD--------- 331
Query: 308 AAAAATAKITAQEAVAGAAVLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVT 367
A++A++ + + E LGT G L++ L L P A A Q G +
Sbjct: 332 -ASSASSFLDSDELERTGIDLGTTGRLQLMA-RLAEGTGLQIPPAAQQALQMSGSLAFGA 389
Query: 368 PARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISG 427
A + + + LS+Q S
Sbjct: 390 VAEFSFVIDLQT------------------------------------RLSQQTEASALA 413
Query: 428 SSARHMVMQKLLRKQESTVMVLRNMVDPK-----DIDDDLEGEVTEECGKFGAVNRVIIY 482
++A ++ + L NM +P+ D +++ +V EEC K G V + IY
Sbjct: 414 AAAS-------VQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGV--IHIY 464
Query: 483 QEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGRKVVA 527
+K + + ++V+ + A+ AL+GRWFAG+ + A
Sbjct: 465 VDKNSAQGN------VYVKCPSIAAAIAAVNALHGRWFAGKMITA 503
Score = 75.5 bits (184), Expect = 1e-13
Identities = 40/98 (40%), Positives = 58/98 (59%)
Query: 89 AHQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSV 148
A Q ++ MA Q+ A R+YVGS+++ + ED +R F PFG I+SI + DS
Sbjct: 227 ASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSE 286
Query: 149 TMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVG 186
T + KG+ F+ + E A+ ALEQ+N L GR +KVG
Sbjct: 287 TGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVG 324
Score = 32.0 bits (71), Expect = 1.5
Identities = 14/65 (21%), Positives = 28/65 (43%)
Query: 198 IDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEY 257
ID L E R ++ + + D++ F GK++ + D + + KG ++E+
Sbjct: 142 IDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEF 201
Query: 258 EKAQS 262
S
Sbjct: 202 VDVSS 206
>gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens]
Length = 524
Score = 100 bits (249), Expect = 3e-21
Identities = 95/405 (23%), Positives = 174/405 (42%), Gaps = 81/405 (20%)
Query: 128 IRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGR 187
+ + F+ G ++ + M D + + KG A+VE+ + LA+ +LG I
Sbjct: 169 LEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRVLGVPIIVQAS 228
Query: 188 PSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTG 247
+ +A + + L + + R+YV S+H ++++D ++ +FE FG+I+S L D TG
Sbjct: 229 QAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETG 288
Query: 248 KHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAV 307
+ KGYGFI + ++ ++ A+ +N F+L G+ ++VG +T T
Sbjct: 289 RSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGH--------VTERTD--------- 331
Query: 308 AAAAATAKITAQEAVAGAAVLGTLGTPGLVSPALTLAQPLGTLPQAVMAAQAPGVITGVT 367
A++A++ + + E LGT G L++ L L P A A Q G +
Sbjct: 332 -ASSASSFLDSDELERTGIDLGTTGRLQLMA-RLAEGTGLQIPPAAQQALQMSGSL---- 385
Query: 368 PARPPIPVTIPSVGVVNPILASPPTLGLLEPKKEKEEEELFPESERPEMLSEQEHMSISG 427
+ G V ++ LS+Q S
Sbjct: 386 -----------AFGAV---------------------------ADLQTRLSQQTEASALA 407
Query: 428 SSARHMVMQKLLRKQESTVMVLRNMVDPK-----DIDDDLEGEVTEECGKFGAVNRVIIY 482
++A ++ + L NM +P+ D +++ +V EEC K G V + IY
Sbjct: 408 AAAS-------VQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDVIEECNKHGGV--IHIY 458
Query: 483 QEKQGEEEDAEIIVKIFVEFSIASETHKAIQALNGRWFAGRKVVA 527
+K + + ++V+ + A+ AL+GRWFAG+ + A
Sbjct: 459 VDKNSAQGN------VYVKCPSIAAAIAAVNALHGRWFAGKMITA 497
Score = 75.5 bits (184), Expect = 1e-13
Identities = 40/98 (40%), Positives = 58/98 (59%)
Query: 89 AHQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSV 148
A Q ++ MA Q+ A R+YVGS+++ + ED +R F PFG I+SI + DS
Sbjct: 227 ASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSE 286
Query: 149 TMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVG 186
T + KG+ F+ + E A+ ALEQ+N L GR +KVG
Sbjct: 287 TGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVG 324
Score = 32.0 bits (71), Expect = 1.5
Identities = 14/65 (21%), Positives = 28/65 (43%)
Query: 198 IDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEY 257
ID L E R ++ + + D++ F GK++ + D + + KG ++E+
Sbjct: 142 IDNLTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEF 201
Query: 258 EKAQS 262
S
Sbjct: 202 VDVSS 206
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 94.4 bits (233), Expect = 2e-19
Identities = 52/172 (30%), Positives = 94/172 (54%), Gaps = 6/172 (3%)
Query: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
+++ ++ + + F+ FG I S + D KG+ FV +E EAA+ A+E+M
Sbjct: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDE--NGSKGYGFVHFETQEAAERAIEKM 158
Query: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 233
N ++L R + VGR + + + +L A+ F +Y+ + +D+ D+ +K +F FG
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREA---ELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFG 215
Query: 234 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 285
S + D + GK KG+GF+ +E+ + +Q AV MN +L G+ + VG+A
Sbjct: 216 PALSVKVMTDES-GKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRA 266
Score = 82.0 bits (201), Expect = 1e-15
Identities = 47/174 (27%), Positives = 90/174 (51%), Gaps = 11/174 (6%)
Query: 111 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 170
M +YVG ++ ++ E + + F+P GPI SI + D +T + G+A+V ++ P A+ AL
Sbjct: 10 MASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
Query: 171 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 230
+ MN ++ G+ +++ Q P + I++ ++ + + + + F
Sbjct: 70 DTMNFDVIKGKPVRI----MWSQRDPSL-----RKSGVGNIFIKNLDKSIDNKALYDTFS 120
Query: 231 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 284
AFG I SC + D KGYGF+ +E ++++ A+ MN L + + VG+
Sbjct: 121 AFGNILSCKVVCDENGS--KGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGR 172
Score = 82.0 bits (201), Expect = 1e-15
Identities = 117/490 (23%), Positives = 194/490 (39%), Gaps = 121/490 (24%)
Query: 62 EQQEALQKA--KKYAMEQSIKSVLVKQTIAHQQQQLTNLQMAAQRQRALAIMCRVYVGSI 119
E QEA ++A K M + + V V + + ++++ ++ A+ + VY+ +
Sbjct: 146 ETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREA---ELGARAKE----FTNVYIKNF 198
Query: 120 YYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLG 179
++ ++ ++ F FGP S+ + D + K KGF FV +E E AQ A+++MN L
Sbjct: 199 GEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEMNGKELN 257
Query: 180 GRNIKVGRPSNIGQAQPIIDQLAEEARAFNR-------------IYVASVHQDLSDDDIK 226
G+ I VGR AQ +++ E R F + +YV ++ + D+ ++
Sbjct: 258 GKQIYVGR------AQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLR 311
Query: 227 SVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMN--------------- 271
F FG I S + + G+ KG+GF+ + + + AV+ MN
Sbjct: 312 KEFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQ 369
Query: 272 -----LFDLGGQYL-RVGKAVTPPMPLLT---PATPGG-----LP---------PAAAVA 308
L QY+ R+ P P++ PA P G +P P + +A
Sbjct: 370 RKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRAAYYPPSQIA 429
Query: 309 AAAATAKITAQEAVAGAAVLGTLGTPGLVSPAL--------------------------T 342
+ + TAQ GA PG + PA T
Sbjct: 430 QLRPSPRWTAQ----GARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQRVANT 485
Query: 343 LAQPLGTLPQAVMAAQAPGVIT--------GV------TPARPPIPVTIPSVGV--VNPI 386
Q +G P A AA P V T GV A+P + + P+V V P+
Sbjct: 486 STQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQGQEPL 545
Query: 387 LASPPTLGLLEPKKEKEEEELFP--ESERPEMLSEQEHM--SISGSSARHMV--MQKLLR 440
AS + +K+ E LFP ++ P + + M I S HM+ + L
Sbjct: 546 TASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESPESLRS 605
Query: 441 KQESTVMVLR 450
K + V VL+
Sbjct: 606 KVDEAVAVLQ 615
Score = 30.4 bits (67), Expect = 4.3
Identities = 21/86 (24%), Positives = 42/86 (48%), Gaps = 10/86 (11%)
Query: 440 RKQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIF 499
R +E T + ++N + D+DD+ + + GKFG V + ++ G+ + F
Sbjct: 186 RAKEFTNVYIKNFGE--DMDDE---RLKDLFGKFGPALSVKVMTDESGKSKGFG-----F 235
Query: 500 VEFSIASETHKAIQALNGRWFAGRKV 525
V F + KA+ +NG+ G+++
Sbjct: 236 VSFERHEDAQKAVDEMNGKELNGKQI 261
>gi|168229150 poly(A) binding protein, cytoplasmic 4-like [Homo
sapiens]
Length = 370
Score = 93.6 bits (231), Expect = 4e-19
Identities = 54/172 (31%), Positives = 94/172 (54%), Gaps = 6/172 (3%)
Query: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
V++ ++ + T+ + F+ FG I S + D KG+AFV ++ AA A+E+M
Sbjct: 100 VFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDD--QGSKGYAFVHFQNQSAADRAIEEM 157
Query: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 233
N +L G + VGR N + +L +A F +Y+ + D+ D+ +K VF +G
Sbjct: 158 NGKLLKGCKVFVGRFKNRKDREA---ELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYG 214
Query: 234 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 285
K S + D ++GK KG+GF+ ++ ++++ AV MN D+ GQ + VG+A
Sbjct: 215 KTLSVKVMTD-SSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRA 265
Score = 75.5 bits (184), Expect = 1e-13
Identities = 46/179 (25%), Positives = 94/179 (52%), Gaps = 10/179 (5%)
Query: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
VY+ + ++ ++ ++ F+ +G S+ + DS + K KGF FV ++ EAA+ A+E+M
Sbjct: 192 VYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDS-SGKSKGFGFVSFDSHEAAKKAVEEM 250
Query: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFN-------RIYVASVHQDLSDDDIK 226
N + G+ I VGR + Q + Q+ E+ + ++Y+ ++ + D+ ++
Sbjct: 251 NGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLR 310
Query: 227 SVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 285
+ F +FG I + ++ G+ KG+G I + + + A++ MN LG + L + A
Sbjct: 311 NEFSSFGSISRVKVMQE--EGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALA 367
Score = 68.2 bits (165), Expect = 2e-11
Identities = 44/174 (25%), Positives = 84/174 (48%), Gaps = 11/174 (6%)
Query: 111 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 170
M +YVG ++ ++ ED + + F+ GP+ SI + D VT + G+A+V + AQ AL
Sbjct: 9 MASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKAL 68
Query: 171 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 230
+ MN ++ G++I++ + +++ ++ + + + + F
Sbjct: 69 DTMNFDIIKGKSIRLMWSQRDAYLR---------RSGIGNVFIKNLDKSIDNKTLYEHFS 119
Query: 231 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 284
AFGKI S + D KGY F+ ++ ++ A+ MN L G + VG+
Sbjct: 120 AFGKILSSKVMSDDQGS--KGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGR 171
>gi|116734698 RNA binding motif protein 23 isoform 3 [Homo sapiens]
Length = 405
Score = 92.4 bits (228), Expect = 9e-19
Identities = 70/241 (29%), Positives = 113/241 (46%), Gaps = 30/241 (12%)
Query: 132 FAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNI 191
F+ G ++ + + D + + KG A+VE+ ++ LA+ +LG I +
Sbjct: 152 FSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEK 211
Query: 192 GQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKG 251
+ + + L + R+YV S+H ++++D ++ +FE FGKI + L +D TG+ KG
Sbjct: 212 NRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKG 271
Query: 252 YGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA---------VTPP------------- 289
YGFI + ++ ++ A+ +N F+L G+ +RVG +T P
Sbjct: 272 YGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGG 331
Query: 290 ----MPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGL--VSPALTL 343
M L LP AA AAAAA Q + GA LG L L +SPAL L
Sbjct: 332 RFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQ--LNGAVPLGALNPAALTALSPALNL 389
Query: 344 A 344
A
Sbjct: 390 A 390
Score = 68.2 bits (165), Expect = 2e-11
Identities = 37/98 (37%), Positives = 56/98 (57%)
Query: 89 AHQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSV 148
A Q ++ MA Q+ R+YVGS+++ + ED +R F PFG I +I + DS
Sbjct: 206 ASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSD 265
Query: 149 TMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVG 186
T + KG+ F+ + E A+ ALEQ+N L GR ++VG
Sbjct: 266 TGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVG 303
Score = 35.0 bits (79), Expect = 0.17
Identities = 15/65 (23%), Positives = 32/65 (49%)
Query: 198 IDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEY 257
+D L+ E R ++ + + D++ F A GK++ + D + + KG ++E+
Sbjct: 121 VDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEF 180
Query: 258 EKAQS 262
+ QS
Sbjct: 181 CEIQS 185
>gi|116734696 RNA binding motif protein 23 isoform 1 [Homo sapiens]
Length = 439
Score = 92.4 bits (228), Expect = 9e-19
Identities = 70/241 (29%), Positives = 113/241 (46%), Gaps = 30/241 (12%)
Query: 132 FAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNI 191
F+ G ++ + + D + + KG A+VE+ ++ LA+ +LG I +
Sbjct: 186 FSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEK 245
Query: 192 GQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKG 251
+ + + L + R+YV S+H ++++D ++ +FE FGKI + L +D TG+ KG
Sbjct: 246 NRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKG 305
Query: 252 YGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA---------VTPP------------- 289
YGFI + ++ ++ A+ +N F+L G+ +RVG +T P
Sbjct: 306 YGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGG 365
Query: 290 ----MPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGL--VSPALTL 343
M L LP AA AAAAA Q + GA LG L L +SPAL L
Sbjct: 366 RFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQ--LNGAVPLGALNPAALTALSPALNL 423
Query: 344 A 344
A
Sbjct: 424 A 424
Score = 68.2 bits (165), Expect = 2e-11
Identities = 37/98 (37%), Positives = 56/98 (57%)
Query: 89 AHQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSV 148
A Q ++ MA Q+ R+YVGS+++ + ED +R F PFG I +I + DS
Sbjct: 240 ASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSD 299
Query: 149 TMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVG 186
T + KG+ F+ + E A+ ALEQ+N L GR ++VG
Sbjct: 300 TGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVG 337
Score = 35.0 bits (79), Expect = 0.17
Identities = 15/65 (23%), Positives = 32/65 (49%)
Query: 198 IDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEY 257
+D L+ E R ++ + + D++ F A GK++ + D + + KG ++E+
Sbjct: 155 VDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEF 214
Query: 258 EKAQS 262
+ QS
Sbjct: 215 CEIQS 219
>gi|116734694 RNA binding motif protein 23 isoform 2 [Homo sapiens]
Length = 423
Score = 92.4 bits (228), Expect = 9e-19
Identities = 70/241 (29%), Positives = 113/241 (46%), Gaps = 30/241 (12%)
Query: 132 FAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNI 191
F+ G ++ + + D + + KG A+VE+ ++ LA+ +LG I +
Sbjct: 170 FSAVGKVRDVRIISDRNSRRSKGIAYVEFCEIQSVPLAIGLTGQRLLGVPIIVQASQAEK 229
Query: 192 GQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKG 251
+ + + L + R+YV S+H ++++D ++ +FE FGKI + L +D TG+ KG
Sbjct: 230 NRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKG 289
Query: 252 YGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA---------VTPP------------- 289
YGFI + ++ ++ A+ +N F+L G+ +RVG +T P
Sbjct: 290 YGFITFSDSECARRALEQLNGFELAGRPMRVGHVTERLDGGTDITFPDGDQELDLGSAGG 349
Query: 290 ----MPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTPGL--VSPALTL 343
M L LP AA AAAAA Q + GA LG L L +SPAL L
Sbjct: 350 RFQLMAKLAEGAGIQLPSTAAAAAAAAAQAAALQ--LNGAVPLGALNPAALTALSPALNL 407
Query: 344 A 344
A
Sbjct: 408 A 408
Score = 68.2 bits (165), Expect = 2e-11
Identities = 37/98 (37%), Positives = 56/98 (57%)
Query: 89 AHQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSV 148
A Q ++ MA Q+ R+YVGS+++ + ED +R F PFG I +I + DS
Sbjct: 224 ASQAEKNRLAAMANNLQKGNGGPMRLYVGSLHFNITEDMLRGIFEPFGKIDNIVLMKDSD 283
Query: 149 TMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVG 186
T + KG+ F+ + E A+ ALEQ+N L GR ++VG
Sbjct: 284 TGRSKGYGFITFSDSECARRALEQLNGFELAGRPMRVG 321
Score = 35.0 bits (79), Expect = 0.17
Identities = 15/65 (23%), Positives = 32/65 (49%)
Query: 198 IDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEY 257
+D L+ E R ++ + + D++ F A GK++ + D + + KG ++E+
Sbjct: 139 VDNLSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEF 198
Query: 258 EKAQS 262
+ QS
Sbjct: 199 CEIQS 203
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 91.7 bits (226), Expect = 2e-18
Identities = 51/172 (29%), Positives = 95/172 (55%), Gaps = 6/172 (3%)
Query: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
++V ++ + + + FG I S ++ D KG+ FV +E EAA+ A+++M
Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDE--NGSKGYGFVHFETHEAAERAIKKM 158
Query: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 233
N ++L GR + VG+ + + + +L A+ F +Y+ + +D+ D+ +K +F FG
Sbjct: 159 NGMLLNGRKVFVGQFKSRKEREA---ELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFG 215
Query: 234 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 285
S + D + GK KG+GF+ +E+ + +Q AV MN +L G+ + VG+A
Sbjct: 216 PALSVKVMTDES-GKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRA 266
Score = 78.2 bits (191), Expect = 2e-14
Identities = 49/171 (28%), Positives = 85/171 (49%), Gaps = 22/171 (12%)
Query: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
VY+ + ++ ++ ++ F FGP S+ + D + K KGF FV +E E AQ A+++M
Sbjct: 193 VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDE-SGKSKGFGFVSFERHEDAQKAVDEM 251
Query: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNR-------------IYVASVHQDL 220
N L G+ I VGR AQ +++ E R F + +YV ++ +
Sbjct: 252 NGKELNGKQIYVGR------AQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGI 305
Query: 221 SDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMN 271
D+ ++ F FG I S + + G+ KG+GF+ + + + AV+ MN
Sbjct: 306 DDERLRKAFSPFGTITSAKVMME--GGRSKGFGFVCFSSPEEATKAVTEMN 354
Score = 74.3 bits (181), Expect = 3e-13
Identities = 45/171 (26%), Positives = 88/171 (51%), Gaps = 11/171 (6%)
Query: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
+YVG ++ ++ E + + F+P GPI SI + D +T +A+V ++ + A+ AL+ M
Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTM 72
Query: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 233
N ++ G+ +++ Q P + I+V ++ + +++ + AFG
Sbjct: 73 NFDVIKGKPVRI----MWSQRDPSL-----RKSGVGNIFVKNLDKSINNKALYDTVSAFG 123
Query: 234 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 284
I SC + D KGYGF+ +E ++++ A+ MN L G+ + VG+
Sbjct: 124 NILSCNVVCDENGS--KGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQ 172
Score = 42.0 bits (97), Expect = 0.001
Identities = 37/150 (24%), Positives = 73/150 (48%), Gaps = 8/150 (5%)
Query: 41 SIKMENGQSTAAKLGLPPLTPEQQEALQKA--KKYAMEQSIKSVLV---KQTIAHQQQQL 95
S+K+ +S +K G ++ E+ E QKA + E + K + V ++ + Q +
Sbjct: 219 SVKVMTDESGKSK-GFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELK 277
Query: 96 TNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGF 155
+ Q + + +YV ++ + ++ +R+AF+PFG I S + + + KGF
Sbjct: 278 RTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRKAFSPFGTITSAKVMMEGG--RSKGF 335
Query: 156 AFVEYEVPEAAQLALEQMNSVMLGGRNIKV 185
FV + PE A A+ +MN ++ + + V
Sbjct: 336 GFVCFSSPEEATKAVTEMNGRIVATKPLYV 365
Score = 29.3 bits (64), Expect = 9.6
Identities = 17/71 (23%), Positives = 35/71 (49%), Gaps = 6/71 (8%)
Query: 456 KDIDDDLEGEVTEEC-GKFGAVNRVIIYQEKQGEEEDAEIIVKIFVEFSIASETHKAIQA 514
K+ +D++ E ++ GKFG V + ++ G+ + FV F + KA+
Sbjct: 196 KNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFG-----FVSFERHEDAQKAVDE 250
Query: 515 LNGRWFAGRKV 525
+NG+ G+++
Sbjct: 251 MNGKELNGKQI 261
>gi|109948285 poly(A) binding protein, cytoplasmic 1-like 2B [Homo
sapiens]
Length = 200
Score = 87.8 bits (216), Expect = 2e-17
Identities = 51/174 (29%), Positives = 94/174 (54%), Gaps = 11/174 (6%)
Query: 111 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 170
M +YVG ++ E+ E + + F+P GPI SI + D +T + G+A+V Y+ P A+ AL
Sbjct: 1 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60
Query: 171 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 230
E +N ++ GR +++ Q P + +++ ++ + + + + ++F
Sbjct: 61 ETLNFDVIKGRPVRI----MWSQRDPSL-----RKSGVGNVFIKNLGKTIDNKALYNIFS 111
Query: 231 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 284
AFG I SC +A D KGYGF+ ++K +S++ A+ MN L + + VG+
Sbjct: 112 AFGNILSCKVACDEK--GPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGR 163
>gi|61175237 poly(A) binding protein, cytoplasmic 1-like 2A [Homo
sapiens]
Length = 200
Score = 87.8 bits (216), Expect = 2e-17
Identities = 51/174 (29%), Positives = 94/174 (54%), Gaps = 11/174 (6%)
Query: 111 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 170
M +YVG ++ E+ E + + F+P GPI SI + D +T + G+A+V Y+ P A+ AL
Sbjct: 1 MASLYVGDLHPEVTEAMLYEKFSPAGPILSIRICRDKITRRSLGYAYVNYQQPVDAKRAL 60
Query: 171 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 230
E +N ++ GR +++ Q P + +++ ++ + + + + ++F
Sbjct: 61 ETLNFDVIKGRPVRI----MWSQRDPSL-----RKSGVGNVFIKNLGKTIDNKALYNIFS 111
Query: 231 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGK 284
AFG I SC +A D KGYGF+ ++K +S++ A+ MN L + + VG+
Sbjct: 112 AFGNILSCKVACDEK--GPKGYGFVHFQKQESAERAIDVMNGMFLNYRKIFVGR 163
>gi|185135971 poly(A)-binding protein, cytoplasmic 1-like [Homo
sapiens]
Length = 614
Score = 85.9 bits (211), Expect = 9e-17
Identities = 75/263 (28%), Positives = 125/263 (47%), Gaps = 36/263 (13%)
Query: 52 AKLGLPPLTPEQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQ---QLTNLQMAAQRQRAL 108
A L + L P+ EA+ +K++ I S+ V + +A ++ N Q A +RAL
Sbjct: 11 ASLYVGDLHPDVTEAMLY-EKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERAL 69
Query: 109 AIM---------CRVY------------VGSIYYELGEDTIRQ-----AFAPFGPIKSID 142
M R+ VG+I+ + ED+I F+ FG I S
Sbjct: 70 DTMNFEMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCK 129
Query: 143 MSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLA 202
++ D +GF FV +E EAAQ A+ MN ++L R + VG + + + +L
Sbjct: 130 VACDE--HGSRGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRREREA---ELG 184
Query: 203 EEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQS 262
A F IYV ++ D+ + ++ +F FGK+ S + RD +G + +GF+ +EK +
Sbjct: 185 ARALEFTNIYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRD-NSGHSRCFGFVNFEKHEE 243
Query: 263 SQDAVSSMNLFDLGGQYLRVGKA 285
+Q AV MN ++ G+ L G+A
Sbjct: 244 AQKAVVHMNGKEVSGRLLYAGRA 266
Score = 79.0 bits (193), Expect = 1e-14
Identities = 47/173 (27%), Positives = 89/173 (51%), Gaps = 11/173 (6%)
Query: 111 MCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLAL 170
+ +YVG ++ ++ E + + F+P GPI SI + D T + G+A++ ++ P A+ AL
Sbjct: 10 LASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERAL 69
Query: 171 EQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 230
+ MN ML G+ I++ Q P + I++ ++ + + + F
Sbjct: 70 DTMNFEMLKGQPIRI----MWSQRDPGL-----RKSGVGNIFIKNLEDSIDNKALYDTFS 120
Query: 231 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVG 283
FG I SC +A D +G+GF+ +E +++Q A+++MN L + + VG
Sbjct: 121 TFGNILSCKVACDEHGS--RGFGFVHFETHEAAQQAINTMNGMLLNDRKVFVG 171
Score = 63.5 bits (153), Expect = 5e-10
Identities = 48/180 (26%), Positives = 87/180 (48%), Gaps = 12/180 (6%)
Query: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
+YV ++ ++ E ++ F+ FG + S+ + D+ + + F FV +E E AQ A+ M
Sbjct: 193 IYVKNLPVDVDEQGLQDLFSQFGKMLSVKVMRDN-SGHSRCFGFVNFEKHEEAQKAVVHM 251
Query: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFN-------RIYVASVHQDLSDDDIK 226
N + GR + GR + Q + + E+ + +YV ++ + DD ++
Sbjct: 252 NGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLR 311
Query: 227 SVFEAFGKIKSCTLARDPTTGKH-KGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 285
F +G I S A+ T G H KG+GF+ + + + AV+ MN +G + L V A
Sbjct: 312 KEFSPYGVITS---AKVMTEGGHSKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALA 368
Score = 39.7 bits (91), Expect = 0.007
Identities = 34/130 (26%), Positives = 61/130 (46%), Gaps = 9/130 (6%)
Query: 62 EQQEALQKAKKYAMEQSIKSVLVKQTIAHQQQQLTNL------QMAAQRQRALAIMCRVY 115
E+ E QKA + + + L+ A ++ + N QM R R + +Y
Sbjct: 239 EKHEEAQKAVVHMNGKEVSGRLLYAGRAQKRVERQNELKRRFEQMKQDRLRRYQGV-NLY 297
Query: 116 VGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQMNS 175
V ++ + +D +R+ F+P+G I S + + KGF FV + PE A A+ +MN
Sbjct: 298 VKNLDDSIDDDKLRKEFSPYGVITSAKVMTEGG--HSKGFGFVCFSSPEEATKAVTEMNG 355
Query: 176 VMLGGRNIKV 185
++G + + V
Sbjct: 356 RIVGTKPLYV 365
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 85.9 bits (211), Expect = 9e-17
Identities = 86/334 (25%), Positives = 135/334 (40%), Gaps = 53/334 (15%)
Query: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
VYVG + ++ E + + F GP+ + M D VT +H+G+ FVE+ E A A++ M
Sbjct: 15 VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDADYAIKIM 74
Query: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 233
N + L G+ I+V + S + + I++ ++ ++ + + F AFG
Sbjct: 75 NMIKLYGKPIRVNKASAHNKNLDV----------GANIFIGNLDPEIDEKLLYDTFSAFG 124
Query: 234 KI-KSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYL------------ 280
I ++ + RDP TG KGY FI + +S A+ +MN GQYL
Sbjct: 125 VILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMN-----GQYLCNRPITVSYAFK 179
Query: 281 ------RVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTP 334
R G A + P + P A + A V+ +LG+
Sbjct: 180 KDSKGERHGSAAERLLAAQNPLSQADRPHQLFADAPPPPS--------APNPVVSSLGS- 230
Query: 335 GLVSPALTLAQPLGTLPQAVMAAQAPGVI-TGVTPARPPIPVTIPSVGVVNPILASPPTL 393
GL P + P G+ P V PG + G+ PA PP P+ + G P +P
Sbjct: 231 GLPPPGM---PPPGSFPPPV---PPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTP--- 281
Query: 394 GLLEPKKEKEEEELFPESERPEMLSEQEHMSISG 427
G P FP P Q ++ G
Sbjct: 282 GAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHG 315
Score = 39.7 bits (91), Expect = 0.007
Identities = 24/86 (27%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Query: 101 AAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPI-KSIDMSWDSVTMKHKGFAFVE 159
A+ + L + +++G++ E+ E + F+ FG I ++ + D T KG+AF+
Sbjct: 89 ASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFIN 148
Query: 160 YEVPEAAQLALEQMNSVMLGGRNIKV 185
+ +A+ A+E MN L R I V
Sbjct: 149 FASFDASDAAIEAMNGQYLCNRPITV 174
>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
Length = 375
Score = 84.7 bits (208), Expect = 2e-16
Identities = 55/182 (30%), Positives = 90/182 (49%), Gaps = 10/182 (5%)
Query: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
+YVG++ ++ E I Q F+ GP K+ M D T + + FVE+ A AL M
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAAM 66
Query: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 233
N + G+ +KV A Q + + F+ ++V + +++ +DIK+ F FG
Sbjct: 67 NGRKIMGKEVKVN------WATTPSSQKKDTSNHFH-VFVGDLSPEITTEDIKAAFAPFG 119
Query: 234 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAV-TPPMPL 292
+I + +D TGK KGYGF+ + +++A+ M LGG+ +R A PP P
Sbjct: 120 RISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPK 179
Query: 293 LT 294
T
Sbjct: 180 ST 181
Score = 69.3 bits (168), Expect = 8e-12
Identities = 49/179 (27%), Positives = 82/179 (45%), Gaps = 17/179 (9%)
Query: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
V+VG + E+ + I+ AFAPFG I + D T K KG+ FV + A+ A++QM
Sbjct: 97 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 156
Query: 174 NSVMLGGRNIKVGRPSNIGQA----------QPIIDQLAEEARAFN-RIYVASVHQDLSD 222
LGGR I+ + A Q D++ ++ N +Y V L++
Sbjct: 157 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 216
Query: 223 DDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLR 281
++ F FG+I + D KGY F+ + +S+ A+ S+N + G ++
Sbjct: 217 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVK 269
Score = 44.3 bits (103), Expect = 3e-04
Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 6/73 (8%)
Query: 112 CRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALE 171
C VY G + L E +RQ F+PFG I I + D KG++FV + E+A A+
Sbjct: 203 CTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIV 256
Query: 172 QMNSVMLGGRNIK 184
+N + G +K
Sbjct: 257 SVNGTTIEGHVVK 269
>gi|4507499 TIA-1 related protein isoform 1 [Homo sapiens]
Length = 375
Score = 83.2 bits (204), Expect = 6e-16
Identities = 56/182 (30%), Positives = 90/182 (49%), Gaps = 10/182 (5%)
Query: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
+YVG++ ++ E I Q F+ GP KS M + + + + FVE+ A AL M
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTS--NDPYCFVEFYEHRDAAAALAAM 68
Query: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 233
N + G+ +KV A Q + + F+ ++V + +++ +DIKS F FG
Sbjct: 69 NGRKILGKEVKVN------WATTPSSQKKDTSNHFH-VFVGDLSPEITTEDIKSAFAPFG 121
Query: 234 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAV-TPPMPL 292
KI + +D TGK KGYGF+ + +++A+ M LGG+ +R A PP P
Sbjct: 122 KISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPK 181
Query: 293 LT 294
T
Sbjct: 182 ST 183
Score = 63.5 bits (153), Expect = 5e-10
Identities = 46/179 (25%), Positives = 79/179 (44%), Gaps = 17/179 (9%)
Query: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
V+VG + E+ + I+ AFAPFG I + D T K KG+ FV + A+ A+ M
Sbjct: 99 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 158
Query: 174 NSVMLGGRNIKVGRPSNIGQA----------QPIIDQLAEEARAFN-RIYVASVHQDLSD 222
LGGR I+ + A Q + + ++ N +Y + L+D
Sbjct: 159 GGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTD 218
Query: 223 DDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLR 281
++ F FG+I + + KGY F+ + +S+ A+ S+N + G ++
Sbjct: 219 QLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAIVSVNGTTIEGHVVK 271
Score = 43.9 bits (102), Expect = 4e-04
Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 6/73 (8%)
Query: 112 CRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALE 171
C VY G I L + +RQ F+PFG I I + KG++FV + E+A A+
Sbjct: 205 CTVYCGGIASGLTDQLMRQTFSPFGQIMEIRV------FPEKGYSFVRFSTHESAAHAIV 258
Query: 172 QMNSVMLGGRNIK 184
+N + G +K
Sbjct: 259 SVNGTTIEGHVVK 271
>gi|18201888 poly(A) binding protein, cytoplasmic 5 [Homo sapiens]
Length = 382
Score = 83.2 bits (204), Expect = 6e-16
Identities = 57/195 (29%), Positives = 99/195 (50%), Gaps = 22/195 (11%)
Query: 101 AAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEY 160
A R R A V+V +I ++ ++ +++ F +GP +S+ + D+ + K KGF FV Y
Sbjct: 188 AEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDA-SGKSKGFGFVRY 246
Query: 161 EVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNR---------- 210
E EAAQ A+ ++ + G+ + VGR AQ I++LAE R F R
Sbjct: 247 ETHEAAQKAVLDLHGKSIDGKVLYVGR------AQKKIERLAELRRRFERLRLKEKSRPP 300
Query: 211 ---IYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAV 267
IY+ ++ + ++D+ +K F +FG I + + G+ KG+G + + + + AV
Sbjct: 301 GVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMME--VGQGKGFGVVCFSSFEEATKAV 358
Query: 268 SSMNLFDLGGQYLRV 282
MN +G + L V
Sbjct: 359 DEMNGRIVGSKPLHV 373
Score = 76.3 bits (186), Expect = 7e-14
Identities = 47/172 (27%), Positives = 87/172 (50%), Gaps = 5/172 (2%)
Query: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
+++ ++ + + F+ FG I S + D KG+A+V ++ AA A+ M
Sbjct: 108 IFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDD--NGSKGYAYVHFDSLAAANRAIWHM 165
Query: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 233
N V L R + VGR + + + F ++V ++ D+ D+ +K +F +G
Sbjct: 166 NGVRLNNRQVYVGRFKF--PEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYG 223
Query: 234 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKA 285
+S + RD +GK KG+GF+ YE +++Q AV ++ + G+ L VG+A
Sbjct: 224 PTESVKVIRD-ASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRA 274
Score = 68.6 bits (166), Expect = 1e-11
Identities = 45/175 (25%), Positives = 85/175 (48%), Gaps = 11/175 (6%)
Query: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
+YVG + ++ ED + + F P GP++ + D VT G+ +V + P A+ AL M
Sbjct: 20 LYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTM 79
Query: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFG 233
N ++ G+P + +QP D+L + I++ ++ + + + + +F AFG
Sbjct: 80 NFDLIN------GKPFRLMWSQP-DDRLRKS--GVGNIFIKNLDKSIDNRALFYLFSAFG 130
Query: 234 KIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTP 288
I SC + D KGY ++ ++ ++ A+ MN L + + VG+ P
Sbjct: 131 NILSCKVVCDDNGS--KGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFP 183
>gi|188219591 TIA1 protein isoform 2 [Homo sapiens]
Length = 386
Score = 82.8 bits (203), Expect = 7e-16
Identities = 52/186 (27%), Positives = 89/186 (47%), Gaps = 7/186 (3%)
Query: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
+YVG++ ++ E I Q F+ GP K+ M D T + + FVE+ A AL M
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMD--TAGNDPYCFVEFHEHRHAAAALAAM 66
Query: 174 NSVMLGGRNIKVGRPSNIGQAQPIIDQLA----EEARAFNRIYVASVHQDLSDDDIKSVF 229
N + G+ +KV + + + ++ ++V + +++ +DIK+ F
Sbjct: 67 NGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAF 126
Query: 230 EAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAV-TP 288
FG+I + +D TGK KGYGF+ + +++A+ M LGG+ +R A P
Sbjct: 127 APFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKP 186
Query: 289 PMPLLT 294
P P T
Sbjct: 187 PAPKST 192
Score = 69.3 bits (168), Expect = 8e-12
Identities = 49/179 (27%), Positives = 82/179 (45%), Gaps = 17/179 (9%)
Query: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
V+VG + E+ + I+ AFAPFG I + D T K KG+ FV + A+ A++QM
Sbjct: 108 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 167
Query: 174 NSVMLGGRNIKVGRPSNIGQA----------QPIIDQLAEEARAFN-RIYVASVHQDLSD 222
LGGR I+ + A Q D++ ++ N +Y V L++
Sbjct: 168 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 227
Query: 223 DDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLR 281
++ F FG+I + D KGY F+ + +S+ A+ S+N + G ++
Sbjct: 228 QLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIVSVNGTTIEGHVVK 280
Score = 44.3 bits (103), Expect = 3e-04
Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 6/73 (8%)
Query: 112 CRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALE 171
C VY G + L E +RQ F+PFG I I + D KG++FV + E+A A+
Sbjct: 214 CTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPD------KGYSFVRFNSHESAAHAIV 267
Query: 172 QMNSVMLGGRNIK 184
+N + G +K
Sbjct: 268 SVNGTTIEGHVVK 280
>gi|77695912 TIA-1 related protein isoform 2 [Homo sapiens]
Length = 392
Score = 77.8 bits (190), Expect = 2e-14
Identities = 57/197 (28%), Positives = 91/197 (46%), Gaps = 23/197 (11%)
Query: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSV------------TMKHKG---FAFV 158
+YVG++ ++ E I Q F+ GP KS M + ++H + FV
Sbjct: 11 LYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCFV 70
Query: 159 EYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQ 218
E+ A AL MN + G+ +KV A Q + + F+ ++V +
Sbjct: 71 EFYEHRDAAAALAAMNGRKILGKEVKVN------WATTPSSQKKDTSNHFH-VFVGDLSP 123
Query: 219 DLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQ 278
+++ +DIKS F FGKI + +D TGK KGYGF+ + +++A+ M LGG+
Sbjct: 124 EITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGR 183
Query: 279 YLRVGKAV-TPPMPLLT 294
+R A PP P T
Sbjct: 184 QIRTNWATRKPPAPKST 200
Score = 63.5 bits (153), Expect = 5e-10
Identities = 46/179 (25%), Positives = 79/179 (44%), Gaps = 17/179 (9%)
Query: 114 VYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQM 173
V+VG + E+ + I+ AFAPFG I + D T K KG+ FV + A+ A+ M
Sbjct: 116 VFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHM 175
Query: 174 NSVMLGGRNIKVGRPSNIGQA----------QPIIDQLAEEARAFN-RIYVASVHQDLSD 222
LGGR I+ + A Q + + ++ N +Y + L+D
Sbjct: 176 GGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTD 235
Query: 223 DDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLR 281
++ F FG+I + + KGY F+ + +S+ A+ S+N + G ++
Sbjct: 236 QLMRQTFSPFGQIMEIRVFPE------KGYSFVRFSTHESAAHAIVSVNGTTIEGHVVK 288
Score = 43.9 bits (102), Expect = 4e-04
Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 6/73 (8%)
Query: 112 CRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALE 171
C VY G I L + +RQ F+PFG I I + KG++FV + E+A A+
Sbjct: 222 CTVYCGGIASGLTDQLMRQTFSPFGQIMEIRV------FPEKGYSFVRFSTHESAAHAIV 275
Query: 172 QMNSVMLGGRNIK 184
+N + G +K
Sbjct: 276 SVNGTTIEGHVVK 288
>gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo
sapiens]
Length = 486
Score = 75.1 bits (183), Expect = 2e-13
Identities = 76/296 (25%), Positives = 126/296 (42%), Gaps = 21/296 (7%)
Query: 113 RVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAA---QLA 169
++++G I L E ++ F FG I + + D T HKG AF+ Y E+A Q A
Sbjct: 55 KLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSA 114
Query: 170 LEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVF 229
L + ++ R I+V +P++ +++ L + +++V +++ S+DD++ +F
Sbjct: 115 LHEQKTLPGMNRPIQV-KPAD-SESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLF 172
Query: 230 EAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMN--------LFDLGGQYLR 281
EAFG I+ CT+ R P G KG F++Y +Q A+++++ L ++
Sbjct: 173 EAFGNIEECTILRGP-DGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFAD 231
Query: 282 VGKAVTPPMPLLTPATPGGLPPAA---AVAAAAATAKITAQEAVAGAAVLGTLGTPGLVS 338
K T G P A A A A + Q A+ + G P
Sbjct: 232 TDKERTMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAF 291
Query: 339 PALTLAQPLGTLPQAVMAAQAPGVITGVTP---ARPPIPVTIPSVGVVNPILASPP 391
A + Q + AA G TP P +P +IPS VN PP
Sbjct: 292 AAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVP-SIPSPIGVNGFTGLPP 346
Score = 39.3 bits (90), Expect = 0.009
Identities = 49/205 (23%), Positives = 77/205 (37%), Gaps = 57/205 (27%)
Query: 7 ALQVNG--------QQGGGSEPAAAAAVVAA--------GDKWKPPQGTDSIKMENGQST 50
AL +NG GG + P A V + G PPQ NGQ
Sbjct: 301 ALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQA-------NGQPA 353
Query: 51 AAKL------GLPPLTPEQQEALQKA----KKYAMEQSIKSVLVKQTIAHQQQQLTNLQM 100
A + P +P + LQ+A ++YA + + + + A Q M
Sbjct: 354 AEAVFANGIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPP----PM 409
Query: 101 AAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEY 160
Q+QR C +++ + E G+ + Q F PFG FV +
Sbjct: 410 IPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLPFG--------------------FVSF 449
Query: 161 EVPEAAQLALEQMNSVMLGGRNIKV 185
+ P +AQ A++ MN +G + +KV
Sbjct: 450 DNPASAQTAIQAMNGFQIGMKRLKV 474
Score = 31.6 bits (70), Expect = 1.9
Identities = 20/90 (22%), Positives = 38/90 (42%), Gaps = 20/90 (22%)
Query: 193 QAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGY 252
Q P+I Q E +++ + Q+ D ++ +F FG
Sbjct: 405 QPPPMIPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLPFG------------------- 445
Query: 253 GFIEYEKAQSSQDAVSSMNLFDLGGQYLRV 282
F+ ++ S+Q A+ +MN F +G + L+V
Sbjct: 446 -FVSFDNPASAQTAIQAMNGFQIGMKRLKV 474
>gi|20373175 musashi 2 isoform a [Homo sapiens]
Length = 328
Score = 75.1 bits (183), Expect = 2e-13
Identities = 52/195 (26%), Positives = 94/195 (48%), Gaps = 17/195 (8%)
Query: 113 RVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQ 172
++++G + ++ D++R F+ FG I+ + D T + +GF FV + P + L Q
Sbjct: 22 KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 81
Query: 173 MNSVMLGGRNI--KVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 230
+ L + I KV P +AQP + +I+V + + +D+K FE
Sbjct: 82 PHHE-LDSKTIDPKVAFPR---RAQP------KMVTRTKKIFVGGLSANTVVEDVKQYFE 131
Query: 231 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPM 290
FGK++ L D TT +H+G+GF+ +E + + V ++ ++ + + KA P
Sbjct: 132 QFGKVEDAMLMFDKTTNRHRGFGFVTFEN-EDVVEKVCEIHFHEINNKMVECKKA-QPKE 189
Query: 291 PLLTPATPG---GLP 302
+ P T G GLP
Sbjct: 190 VMFPPGTRGRARGLP 204
>gi|25121993 musashi 2 isoform b [Homo sapiens]
Length = 251
Score = 75.1 bits (183), Expect = 2e-13
Identities = 52/195 (26%), Positives = 94/195 (48%), Gaps = 17/195 (8%)
Query: 113 RVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAAQLALEQ 172
++++G + ++ D++R F+ FG I+ + D T + +GF FV + P + L Q
Sbjct: 18 KMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQ 77
Query: 173 MNSVMLGGRNI--KVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFE 230
+ L + I KV P +AQP + +I+V + + +D+K FE
Sbjct: 78 PHHE-LDSKTIDPKVAFPR---RAQP------KMVTRTKKIFVGGLSANTVVEDVKQYFE 127
Query: 231 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPM 290
FGK++ L D TT +H+G+GF+ +E + + V ++ ++ + + KA P
Sbjct: 128 QFGKVEDAMLMFDKTTNRHRGFGFVTFEN-EDVVEKVCEIHFHEINNKMVECKKA-QPKE 185
Query: 291 PLLTPATPG---GLP 302
+ P T G GLP
Sbjct: 186 VMFPPGTRGRARGLP 200
Score = 45.4 bits (106), Expect = 1e-04
Identities = 15/49 (30%), Positives = 31/49 (63%)
Query: 209 NRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEY 257
+++++ + S D ++ F FG+I+ C + RDPTT + +G+GF+ +
Sbjct: 17 SKMFIGGLSWQTSPDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTF 65
>gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo
sapiens]
Length = 448
Score = 74.7 bits (182), Expect = 2e-13
Identities = 78/296 (26%), Positives = 122/296 (41%), Gaps = 31/296 (10%)
Query: 113 RVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAA---QLA 169
++++G I L E ++ F FG I + + D T HKG AF+ Y E+A Q A
Sbjct: 55 KLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSA 114
Query: 170 LEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVF 229
L + + L G N + Q +P + E R +++V +++ S+DD++ +F
Sbjct: 115 LHEQKT--LPGMNRPI-------QVKPADSESRGEDR---KLFVGMLNKQQSEDDVRRLF 162
Query: 230 EAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMN--------LFDLGGQYLR 281
EAFG I+ CT+ R P G KG F++Y +Q A+++++ L ++
Sbjct: 163 EAFGNIEECTILRGP-DGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFAD 221
Query: 282 VGKAVTPPMPLLTPATPGGLPPAA---AVAAAAATAKITAQEAVAGAAVLGTLGTPGLVS 338
K T G P A A A A + Q A+ + G P
Sbjct: 222 TDKERTMRRMQQMAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAF 281
Query: 339 PALTLAQPLGTLPQAVMAAQAPGVITGVTP---ARPPIPVTIPSVGVVNPILASPP 391
A + Q + AA G TP P +P +IPS VN PP
Sbjct: 282 AAAQMQQMAALNMNGLAAAPMTPTSGGSTPPGITAPAVP-SIPSPIGVNGFTGLPP 336
Score = 32.3 bits (72), Expect = 1.1
Identities = 15/52 (28%), Positives = 28/52 (53%)
Query: 231 AFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRV 282
A+G+I P + + GF+ ++ S+Q A+ +MN F +G + L+V
Sbjct: 385 AYGQISQAFPQPPPMIPQQQREGFVSFDNPASAQTAIQAMNGFQIGMKRLKV 436
>gi|187761299 bruno-like 4, RNA binding protein isoform 2 [Homo
sapiens]
Length = 485
Score = 74.7 bits (182), Expect = 2e-13
Identities = 47/162 (29%), Positives = 88/162 (54%), Gaps = 6/162 (3%)
Query: 113 RVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEYEVPEAA---QLA 169
++++G I L E ++ F FG I + + D T HKG AF+ Y E+A Q A
Sbjct: 55 KLFIGQIPRNLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSA 114
Query: 170 LEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVF 229
L + ++ R I+V +P++ +++ L + +++V +++ S+DD++ +F
Sbjct: 115 LHEQKTLPGMNRPIQV-KPAD-SESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLF 172
Query: 230 EAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMN 271
EAFG I+ CT+ R P G KG F++Y +Q A+++++
Sbjct: 173 EAFGNIEECTILRGP-DGNSKGCAFVKYSSHAEAQAAINALH 213
Score = 39.3 bits (90), Expect = 0.009
Identities = 49/205 (23%), Positives = 77/205 (37%), Gaps = 57/205 (27%)
Query: 7 ALQVNG--------QQGGGSEPAAAAAVVAA--------GDKWKPPQGTDSIKMENGQST 50
AL +NG GG + P A V + G PPQ NGQ
Sbjct: 300 ALNMNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQA-------NGQPA 352
Query: 51 AAKL------GLPPLTPEQQEALQKA----KKYAMEQSIKSVLVKQTIAHQQQQLTNLQM 100
A + P +P + LQ+A ++YA + + + + A Q M
Sbjct: 353 AEAVFANGIHPYPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPP----PM 408
Query: 101 AAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAFVEY 160
Q+QR C +++ + E G+ + Q F PFG FV +
Sbjct: 409 IPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLPFG--------------------FVSF 448
Query: 161 EVPEAAQLALEQMNSVMLGGRNIKV 185
+ P +AQ A++ MN +G + +KV
Sbjct: 449 DNPASAQTAIQAMNGFQIGMKRLKV 473
Score = 31.6 bits (70), Expect = 1.9
Identities = 20/90 (22%), Positives = 38/90 (42%), Gaps = 20/90 (22%)
Query: 193 QAQPIIDQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGY 252
Q P+I Q E +++ + Q+ D ++ +F FG
Sbjct: 404 QPPPMIPQQQREGPEGCNLFIYHLPQEFGDAELMQMFLPFG------------------- 444
Query: 253 GFIEYEKAQSSQDAVSSMNLFDLGGQYLRV 282
F+ ++ S+Q A+ +MN F +G + L+V
Sbjct: 445 -FVSFDNPASAQTAIQAMNGFQIGMKRLKV 473
>gi|224549005 RNA binding motif protein 17 [Homo sapiens]
Length = 401
Score = 74.3 bits (181), Expect = 3e-13
Identities = 40/101 (39%), Positives = 62/101 (61%), Gaps = 3/101 (2%)
Query: 441 KQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFV 500
K + V++LRNMV ++D+DLE E EEC K+G V + +I++ +++A V+IF+
Sbjct: 301 KCPTKVVLLRNMVGAGEVDEDLEVETKEECEKYGKVGKCVIFEIPGAPDDEA---VRIFL 357
Query: 501 EFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLS 541
EF KA+ LNGR+F GR V A Y+ ++F DL+
Sbjct: 358 EFERVESAIKAVVDLNGRYFGGRVVKACFYNLDKFRVLDLA 398
Score = 30.0 bits (66), Expect = 5.6
Identities = 19/74 (25%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 209 NRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYG-FIEYEKAQSSQDAV 267
N + V +DL + + K E +GK+ C + P + F+E+E+ +S+ AV
Sbjct: 311 NMVGAGEVDEDL-EVETKEECEKYGKVGKCVIFEIPGAPDDEAVRIFLEFERVESAIKAV 369
Query: 268 SSMNLFDLGGQYLR 281
+N GG+ ++
Sbjct: 370 VDLNGRYFGGRVVK 383
>gi|14249678 RNA binding motif protein 17 [Homo sapiens]
Length = 401
Score = 74.3 bits (181), Expect = 3e-13
Identities = 40/101 (39%), Positives = 62/101 (61%), Gaps = 3/101 (2%)
Query: 441 KQESTVMVLRNMVDPKDIDDDLEGEVTEECGKFGAVNRVIIYQEKQGEEEDAEIIVKIFV 500
K + V++LRNMV ++D+DLE E EEC K+G V + +I++ +++A V+IF+
Sbjct: 301 KCPTKVVLLRNMVGAGEVDEDLEVETKEECEKYGKVGKCVIFEIPGAPDDEA---VRIFL 357
Query: 501 EFSIASETHKAIQALNGRWFAGRKVVAEVYDQERFDNSDLS 541
EF KA+ LNGR+F GR V A Y+ ++F DL+
Sbjct: 358 EFERVESAIKAVVDLNGRYFGGRVVKACFYNLDKFRVLDLA 398
Score = 30.0 bits (66), Expect = 5.6
Identities = 19/74 (25%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 209 NRIYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYG-FIEYEKAQSSQDAV 267
N + V +DL + + K E +GK+ C + P + F+E+E+ +S+ AV
Sbjct: 311 NMVGAGEVDEDL-EVETKEECEKYGKVGKCVIFEIPGAPDDEAVRIFLEFERVESAIKAV 369
Query: 268 SSMNLFDLGGQYLR 281
+N GG+ ++
Sbjct: 370 VDLNGRYFGGRVVK 383
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,887,608
Number of Sequences: 37866
Number of extensions: 1024702
Number of successful extensions: 7713
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 273
Number of HSP's successfully gapped in prelim test: 376
Number of HSP's that attempted gapping in prelim test: 5621
Number of HSP's gapped (non-prelim): 1850
length of query: 542
length of database: 18,247,518
effective HSP length: 107
effective length of query: 435
effective length of database: 14,195,856
effective search space: 6175197360
effective search space used: 6175197360
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.