Guide to the Human Genome
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Search of human proteins with 17149834

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|17149834 sortilin 1 preproprotein [Homo sapiens]
         (831 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|17149834 sortilin 1 preproprotein [Homo sapiens]                  1714   0.0  
gi|4507157 sortilin-related receptor containing LDLR class A rep...   250   3e-66
gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens]     237   4e-62
gi|61743975 SORCS receptor 1 isoform b [Homo sapiens]                 226   7e-59
gi|61743973 SORCS receptor 1 isoform a [Homo sapiens]                 226   7e-59
gi|18379346 VPS10 domain receptor protein SORCS 3 [Homo sapiens]      215   2e-55
gi|24025682 F-box and leucine-rich repeat protein 16 [Homo sapiens]    34   0.49 
gi|7705881 zinc finger protein 580 [Homo sapiens]                      34   0.49 
gi|46361970 zinc finger protein 580 [Homo sapiens]                     34   0.49 
gi|6631075 BCL2-associated athanogene 4 [Homo sapiens]                 33   0.83 
gi|169172087 PREDICTED: hypothetical protein [Homo sapiens]            33   1.1  
gi|113419362 PREDICTED: hypothetical protein [Homo sapiens]            33   1.1  
gi|113418886 PREDICTED: hypothetical protein [Homo sapiens]            33   1.1  
gi|113419893 PREDICTED: hypothetical protein [Homo sapiens]            33   1.1  
gi|33239445 eukaryotic translation initiation factor 3, subunit ...    32   1.9  
gi|83367072 eukaryotic translation initiation factor 3, subunit ...    32   1.9  
gi|148236531 hypothetical protein LOC339779 [Homo sapiens]             32   1.9  
gi|18426904 Werner helicase interacting protein isoform 2 [Homo ...    32   3.2  
gi|18426902 Werner helicase interacting protein isoform 1 [Homo ...    32   3.2  
gi|16753221 cadherin 22 precursor [Homo sapiens]                       32   3.2  
gi|113426467 PREDICTED: UPF0607 protein ENSP00000381418-like [Ho...    31   4.1  
gi|21217561 Shaw-related voltage-gated potassium channel protein...    31   4.1  
gi|21217563 Shaw-related voltage-gated potassium channel protein...    31   4.1  
gi|24497458 Shaw-related voltage-gated potassium channel protein...    31   4.1  
gi|113426153 PREDICTED: UPF0607 protein ENSP00000381418-like [Ho...    31   5.4  
gi|95147555 microtubule-associated protein 1A [Homo sapiens]           31   5.4  
gi|225735557 nuclear factor erythroid 2-like 3 [Homo sapiens]          31   5.4  
gi|226053185 paternally expressed 3 isoform 3 [Homo sapiens]           30   7.1  
gi|226053169 paternally expressed 3 isoform 1 [Homo sapiens]           30   7.1  
gi|226053148 paternally expressed 3 isoform 2 [Homo sapiens]           30   7.1  

>gi|17149834 sortilin 1 preproprotein [Homo sapiens]
          Length = 831

 Score = 1714 bits (4439), Expect = 0.0
 Identities = 831/831 (100%), Positives = 831/831 (100%)

Query: 1   MERPWGAADGLSRWPHGLGLLLLLQLLPPSTLSQDRLDAPPPPAAPLPRWSGPIGVSWGL 60
           MERPWGAADGLSRWPHGLGLLLLLQLLPPSTLSQDRLDAPPPPAAPLPRWSGPIGVSWGL
Sbjct: 1   MERPWGAADGLSRWPHGLGLLLLLQLLPPSTLSQDRLDAPPPPAAPLPRWSGPIGVSWGL 60

Query: 61  RAAAAGGAFPRGGRWRRSAPGEDEECGRVRDFVAKLANNTHQHVFDDLRGSVSLSWVGDS 120
           RAAAAGGAFPRGGRWRRSAPGEDEECGRVRDFVAKLANNTHQHVFDDLRGSVSLSWVGDS
Sbjct: 61  RAAAAGGAFPRGGRWRRSAPGEDEECGRVRDFVAKLANNTHQHVFDDLRGSVSLSWVGDS 120

Query: 121 TGVILVLTTFHVPLVIMTFGQSKLYRSEDYGKNFKDITDLINNTFIRTEFGMAIGPENSG 180
           TGVILVLTTFHVPLVIMTFGQSKLYRSEDYGKNFKDITDLINNTFIRTEFGMAIGPENSG
Sbjct: 121 TGVILVLTTFHVPLVIMTFGQSKLYRSEDYGKNFKDITDLINNTFIRTEFGMAIGPENSG 180

Query: 181 KVVLTAEVSGGSRGGRIFRSSDFAKNFVQTDLPFHPLTQMMYSPQNSDYLLALSTENGLW 240
           KVVLTAEVSGGSRGGRIFRSSDFAKNFVQTDLPFHPLTQMMYSPQNSDYLLALSTENGLW
Sbjct: 181 KVVLTAEVSGGSRGGRIFRSSDFAKNFVQTDLPFHPLTQMMYSPQNSDYLLALSTENGLW 240

Query: 241 VSKNFGGKWEEIHKAVCLAKWGSDNTIFFTTYANGSCKADLGALELWRTSDLGKSFKTIG 300
           VSKNFGGKWEEIHKAVCLAKWGSDNTIFFTTYANGSCKADLGALELWRTSDLGKSFKTIG
Sbjct: 241 VSKNFGGKWEEIHKAVCLAKWGSDNTIFFTTYANGSCKADLGALELWRTSDLGKSFKTIG 300

Query: 301 VKIYSFGLGGRFLFASVMADKDTTRRIHVSTDQGDTWSMAQLPSVGQEQFYSILAANDDM 360
           VKIYSFGLGGRFLFASVMADKDTTRRIHVSTDQGDTWSMAQLPSVGQEQFYSILAANDDM
Sbjct: 301 VKIYSFGLGGRFLFASVMADKDTTRRIHVSTDQGDTWSMAQLPSVGQEQFYSILAANDDM 360

Query: 361 VFMHVDEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGETDFTNVTSLRGVYITSVLS 420
           VFMHVDEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGETDFTNVTSLRGVYITSVLS
Sbjct: 361 VFMHVDEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGETDFTNVTSLRGVYITSVLS 420

Query: 421 EDNSIQTMITFDQGGRWTHLRKPENSECDATAKNKNECSLHIHASYSISQKLNVPMAPLS 480
           EDNSIQTMITFDQGGRWTHLRKPENSECDATAKNKNECSLHIHASYSISQKLNVPMAPLS
Sbjct: 421 EDNSIQTMITFDQGGRWTHLRKPENSECDATAKNKNECSLHIHASYSISQKLNVPMAPLS 480

Query: 481 EPNAVGIVIAHGSVGDAISVMVPDVYISDDGGYSWTKMLEGPHYYTILDSGGIIVAIEHS 540
           EPNAVGIVIAHGSVGDAISVMVPDVYISDDGGYSWTKMLEGPHYYTILDSGGIIVAIEHS
Sbjct: 481 EPNAVGIVIAHGSVGDAISVMVPDVYISDDGGYSWTKMLEGPHYYTILDSGGIIVAIEHS 540

Query: 541 SRPINVIKFSTDEGQCWQTYTFTRDPIYFTGLASEPGARSMNISIWGFTESFLTSQWVSY 600
           SRPINVIKFSTDEGQCWQTYTFTRDPIYFTGLASEPGARSMNISIWGFTESFLTSQWVSY
Sbjct: 541 SRPINVIKFSTDEGQCWQTYTFTRDPIYFTGLASEPGARSMNISIWGFTESFLTSQWVSY 600

Query: 601 TIDFKDILERNCEEKDYTIWLAHSTDPEDYEDGCILGYKEQFLRLRKSSVCQNGRDYVVT 660
           TIDFKDILERNCEEKDYTIWLAHSTDPEDYEDGCILGYKEQFLRLRKSSVCQNGRDYVVT
Sbjct: 601 TIDFKDILERNCEEKDYTIWLAHSTDPEDYEDGCILGYKEQFLRLRKSSVCQNGRDYVVT 660

Query: 661 KQPSICLCSLEDFLCDFGYYRPENDSKCVEQPELKGHDLEFCLYGREEHLTTNGYRKIPG 720
           KQPSICLCSLEDFLCDFGYYRPENDSKCVEQPELKGHDLEFCLYGREEHLTTNGYRKIPG
Sbjct: 661 KQPSICLCSLEDFLCDFGYYRPENDSKCVEQPELKGHDLEFCLYGREEHLTTNGYRKIPG 720

Query: 721 DKCQGGVNPVREVKDLKKKCTSNFLSPEKQNSKSNSVPIILAIVGLMLVTVVAGVLIVKK 780
           DKCQGGVNPVREVKDLKKKCTSNFLSPEKQNSKSNSVPIILAIVGLMLVTVVAGVLIVKK
Sbjct: 721 DKCQGGVNPVREVKDLKKKCTSNFLSPEKQNSKSNSVPIILAIVGLMLVTVVAGVLIVKK 780

Query: 781 YVCGGRFLVHRYSVLQQHAEANGVDGVDALDTASHTNKSGYHDDSDEDLLE 831
           YVCGGRFLVHRYSVLQQHAEANGVDGVDALDTASHTNKSGYHDDSDEDLLE
Sbjct: 781 YVCGGRFLVHRYSVLQQHAEANGVDGVDALDTASHTNKSGYHDDSDEDLLE 831


>gi|4507157 sortilin-related receptor containing LDLR class A
           repeats preproprotein [Homo sapiens]
          Length = 2214

 Score =  250 bits (639), Expect = 3e-66
 Identities = 224/766 (29%), Positives = 350/766 (45%), Gaps = 100/766 (13%)

Query: 20  LLLLLQLLPPSTLSQDRLDAPPPPAAPLPRWSGPIGVSWG---LRAAAAGGAFPRGGRWR 76
           L  L+ LLPP  L +         +APLP+  G + V      LR  A G A  RG    
Sbjct: 15  LFTLVALLPPGALCEVWTQRLHGGSAPLPQDRGFLVVQGDPRELRLWARGDA--RGASRA 72

Query: 77  RSAPGEDEECGRVRDFVAKLANNTHQHVFDDLRGSVSLSWVGDSTGVILVLTTFHVPLVI 136
              P   +    ++    K+     Q   +D    + + W G+ + VI+ L      L +
Sbjct: 73  DEKPLRRKRSAALQPEPIKVYG---QVSLNDSHNQMVVHWAGEKSNVIVALA--RDSLAL 127

Query: 137 MTFGQSKLYRSEDYGKNFKDITDLINNTFIRTEFGMAIGPENSGKVVLTAEVSGGSRGGR 196
                S +Y S DYGK+FK I+D +N       FG+      S  V+     S       
Sbjct: 128 ARPKSSDVYVSYDYGKSFKKISDKLN-------FGLG---NRSEAVIAQFYHSPADNKRY 177

Query: 197 IFRSS---------DFAKNFVQTDLPFHPLTQMMYSPQNSDYLLALSTENG---LWVSKN 244
           IF  +         DF        +PF     +++S + S+ LL     +    LW S +
Sbjct: 178 IFADAYAQYLWITFDFCNTLQGFSIPFRAADLLLHS-KASNLLLGFDRSHPNKQLWKSDD 236

Query: 245 FGGKWEEIHKAVCLAKWGSD-----NTIFFTTYANGSCKADLGALELWRTSDLGKSFKTI 299
           FG  W  I + V    WG D     NTI+   +         G   ++R++D  +S +  
Sbjct: 237 FGQTWIMIQEHVKSFSWGIDPYDKPNTIYIERHEPS------GYSTVFRSTDFFQSRENQ 290

Query: 300 GV---KIYSFGLGGRFLFASVM-----ADKDTTRRIHVSTDQGDTWSMAQLPSVGQEQFY 351
            V   ++  F L  +++FA+ +     +++ ++ ++ VS  +      AQ  +      Y
Sbjct: 291 EVILEEVRDFQLRDKYMFATKVVHLLGSEQQSSVQLWVSFGR-KPMRAAQFVTRHPINEY 349

Query: 352 SILAANDDMVFMHVDEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGE---------- 401
            I  A++D VF+ V    +     ++ S+  G+ +S SL+  LY + GG           
Sbjct: 350 YIADASEDQVFVCVSHSNNRT--NLYISEAEGLKFSLSLENVLYYSPGGAGSDTLVRYFA 407

Query: 402 ----TDFTNVTSLRGVYITSVLS---EDNSIQTMITFDQGGRWTHLRKP------ENSEC 448
                DF  V  L+GVYI ++++    + +++++ITFD+GG W  L+ P      E   C
Sbjct: 408 NEPFADFHRVEGLQGVYIATLINGSMNEENMRSVITFDKGGTWEFLQAPAFTGYGEKINC 467

Query: 449 DATAKNKNECSLHIHASYSISQKLNVP---MAPLSEPNAVGIVIAHGSVGDAISVMVPDV 505
           + +      CSLH+  +  +SQ LN+    M  LS+ +A G++IA GSVG  ++    +V
Sbjct: 468 ELS----QGCSLHL--AQRLSQLLNLQLRRMPILSKESAPGLIIATGSVGKNLASKT-NV 520

Query: 506 YISDDGGYSWTKMLEGPHYYTILDSGGIIVAIEHSSRPINVIKFSTDEGQCWQTYTFTRD 565
           YIS   G  W + L GPHYYT  D GGII AI       N +K+ST+EG+ W+T+ F+  
Sbjct: 521 YISSSAGARWREALPGPHYYTWGDHGGIITAIAQGMET-NELKYSTNEGETWKTFIFSEK 579

Query: 566 PIYFTGLASEPGARSMNISIWGFTESFLTSQWVSYTIDFKDILERNCEEKDYTIWLAHST 625
           P++  GL +EPG +S   +I+G  +  + S W+   ++  D L   C E DY +W    +
Sbjct: 580 PVFVYGLLTEPGEKSTVFTIFGSNKENVHS-WLILQVNATDALGVPCTENDYKLW----S 634

Query: 626 DPEDYEDGCILGYKEQFLRLRKSSVCQNGRDYVVTKQPSICLCSLEDFLCDFGYYRPEND 685
             ++  + C+LG+K  F R    + C NG D+      S C C+ ED+ CDFG+   E+ 
Sbjct: 635 PSDERGNECLLGHKTVFKRRTPHATCFNGEDFDRPVVVSNCSCTREDYECDFGFKMSEDL 694

Query: 686 S--KCVEQPELKGHDLE---FCLYGREEHLTTNGYRKIPGDKCQGG 726
           S   CV  PE  G        C  G   +  T GYRKI GD C GG
Sbjct: 695 SLEVCVPDPEFSGKSYSPPVPCPVG-STYRRTRGYRKISGDTCSGG 739


>gi|170014689 VPS10 domain receptor protein SORCS 2 [Homo sapiens]
          Length = 1159

 Score =  237 bits (604), Expect = 4e-62
 Identities = 190/722 (26%), Positives = 330/722 (45%), Gaps = 81/722 (11%)

Query: 39  APPPPAAPLPRWSGPIGVSWGLRAAAAGGAFPRGGRWRRSAPGEDEECGRVRDFVAKLAN 98
           AP P   P P   GP     G   A A G      RW R+AP      G        L +
Sbjct: 93  APGPSPGPAP---GP-----GEDGAPAAGY----RRWERAAP----LAGVASRAQVSLIS 136

Query: 99  NTHQHVFDDLRGSVSLSWVGDSTGVILVLTTFHVPLVIMTFGQSKLYRSEDYGKNFKDIT 158
            +     D       + W G+++ VIL+LT ++   +     +S L+RS D+G ++  +T
Sbjct: 137 TSFVLKGDATHNQAMVHWTGENSSVILILTKYYHADMGKVL-ESSLWRSSDFGTSYTKLT 195

Query: 159 DLINNTFIRTEFGMAIGPENSGKVVLTAEVSGGSRGGRIFRSSDFAKNFVQTDLPFHPLT 218
                T +   F   I P N  KV+L +  S   R   +F S+D    F +  +PF   T
Sbjct: 196 LQPGVTTVIDNF--YICPTNKRKVILVSS-SLSDRDQSLFLSADEGATFQKQPIPFFVET 252

Query: 219 QMMYSPQNSDYLLALSTENGLWVSKNFGGKWEEIHKAVCLAKWGSDNTIFFTTYANGSCK 278
            +++ P+  D +LA + E+ L+VS + G KW  + + V       D+   F + +     
Sbjct: 253 -LIFHPKEEDKVLAYTKESKLYVSSDLGKKWTLLQERVT-----KDHV--FWSVSGVDAD 304

Query: 279 ADLGALELWRTSDLGKSFKTIGVKIY------------------SFGLGGRFLFASVMAD 320
            DL  +E     DLG  F+ +   I+                  S  +   ++F    + 
Sbjct: 305 PDLVHVE---AQDLGGDFRYVTCAIHNCSEKMLTAPFAGPIDHGSLTVQDDYIFFKATSA 361

Query: 321 KDTTRRIHVSTDQGDTWSMAQLPSVGQEQFYSILAANDDMVFMHVDEPGDTGFGTIFTSD 380
             T  + +VS  + + + + +LP     +   I++ ++  VF+ V E        ++ SD
Sbjct: 362 NQT--KYYVSYRRNE-FVLMKLPKYALPKDLQIISTDESQVFVAVQEWYQMDTYNLYQSD 418

Query: 381 DRGIVYSKSLDRHLYTTTGGETDFTNVTSLRGVYITSVLSE--DNSIQTMITFDQGGRWT 438
            RG+ Y+  L     +    E+   ++  +RGV    + ++  D  + T+IT+++G  W 
Sbjct: 419 PRGVRYALVLQDVRSSRQAEESVLIDILEVRGVKGVFLANQKIDGKVMTLITYNKGRDWD 478

Query: 439 HLRKPENSECDATAKNKN----ECSLHIHASYSISQKLNVPMAPLSEPNAVGIVIAHGSV 494
           +LR P     D   K  N    +C LH+H  ++ +  ++  +   ++  A G+++  G++
Sbjct: 479 YLRPPS---MDMNGKPTNCKPPDCHLHLHLRWADNPYVSGTVH--TKDTAPGLIMGAGNL 533

Query: 495 GDAISVMVPDVYISDDGGYSWTKMLEGPHYYTILDSGGIIVAIEHSSRPINVIKFSTDEG 554
           G  +     ++YI+ D G++W ++ E  H+   LD GG+IVAI+ +S P+ ++KFS DEG
Sbjct: 534 GSQLVEYKEEMYITSDCGHTWRQVFEEEHHILYLDHGGVIVAIKDTSIPLKILKFSVDEG 593

Query: 555 QCWQTYTFTRDPIYFTGLASEPGARSMNISIWGFTESFLTSQWVSYTIDFKDILERNCEE 614
             W T+ FT   ++  GL SEPG  ++ ++++G       S W    +DF+    R C E
Sbjct: 594 LTWSTHNFTSTSVFVDGLLSEPGDETLVMTVFGHIS--FRSDWELVKVDFRPSFSRQCGE 651

Query: 615 KDYTIWLAHSTDPEDYEDGCILGYKEQFLRLRKSSVCQNGRDYVVTKQPSICLCSLEDFL 674
           +DY+ W   +       D CI+G +  F + + +S C  GR +       +C C   DFL
Sbjct: 652 EDYSSWELSNLQ----GDRCIMGQQRSFRKRKSTSWCIKGRSFTSALTSRVCECRDSDFL 707

Query: 675 CDFGYYRPEND----SKCVE----QPELKGHDLEFCLYGREEHLTTNGYRKIPGDKCQGG 726
           CD+G+ R  +     +KC       P     D   C  G + + ++ GYRK+  + C+GG
Sbjct: 708 CDYGFERSSSSESSTNKCSANFWFNPLSPPDD---CALG-QTYTSSLGYRKVVSNVCEGG 763

Query: 727 VN 728
           V+
Sbjct: 764 VD 765


>gi|61743975 SORCS receptor 1 isoform b [Homo sapiens]
          Length = 1198

 Score =  226 bits (576), Expect = 7e-59
 Identities = 169/678 (24%), Positives = 316/678 (46%), Gaps = 54/678 (7%)

Query: 82  EDEECGRVRDFVAKLANNTHQHVFDDLRGSVSLSWVGDSTGVILVLTTFHVPLVIMTFGQ 141
           + ++  R R    +L + T     D       + W G ++ VIL+LT  +    + +  +
Sbjct: 146 DPDKATRFRMEELRLTSTTFALTGDSAHNQAMVHWSGHNSSVILILTKLY-DYNLGSITE 204

Query: 142 SKLYRSEDYGKNFKDITDLINNTFIRTEFGMAIGPENSGKVVLTAEVSGGSRGGRIFRSS 201
           S L+RS DYG  ++ + D +    I +   + + P N  K++L  +    S    +  SS
Sbjct: 205 SSLWRSTDYGTTYEKLNDKVGLKTILSY--LYVCPTNKRKIMLLTDPEIESS---LLISS 259

Query: 202 DFAKNFVQTDLPFHPLTQMMYSPQNSDYLLALSTENGLWVSKNFGGKWEEIHKAVCLAKW 261
           D    + +  L F+ +  +++ P+  D++LA S +  L+ S  FG +W+ I + V   + 
Sbjct: 260 DEGATYQKYRLNFY-IQSLLFHPKQEDWILAYSQDQKLYSSAEFGRRWQLIQEGVVPNR- 317

Query: 262 GSDNTIFFTTYANGSCKADLGALELWRTSDLGKSFKTIGVKIY----------------S 305
                 F+ +    + + DL  LE  RT D    + T  ++                  S
Sbjct: 318 ------FYWSVMGSNKEPDLVHLEA-RTVDGHSHYLTCRMQNCTEANRNQPFPGYIDPDS 370

Query: 306 FGLGGRFLFASVMADKDTTRRIHVSTDQGDTWSMAQLPSVGQEQFYSILAANDDMVFMHV 365
             +   ++F  + +     R  +  + + + ++  +LP     +   +++ +++ VF  V
Sbjct: 371 LIVQDHYVFVQLTSGG---RPHYYVSYRRNAFAQMKLPKYALPKDMHVISTDENQVFAAV 427

Query: 366 DEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGE----TDFTNVTSLRGVYITSVLSE 421
            E        ++ SD RG+ ++ +L+ ++ ++ G E     D   V  ++G+++ +    
Sbjct: 428 QEWNQNDTYNLYISDTRGVYFTLALE-NVQSSRGPEGNIMIDLYEVAGIKGMFLANK-KI 485

Query: 422 DNSIQTMITFDQGGRWTHLRKPENS-ECDATAKNKNECSLHIHASYSISQKLNVPMAPLS 480
           DN ++T IT+++G  W  L+ P+     D        CSLH+H   S +   +  +A  S
Sbjct: 486 DNQVKTFITYNKGRDWRLLQAPDTDLRGDPVHCLLPYCSLHLHLKVSENPYTSGIIA--S 543

Query: 481 EPNAVGIVIAHGSVGDAISVMVPDVYISDDGGYSWTKMLEGPHYYTILDSGGIIVAIEHS 540
           +  A  I++A G++G  +S     +++S D G +W ++ E  H    LD GG++VA++H+
Sbjct: 544 KDTAPSIIVASGNIGSELSDTDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAMKHT 603

Query: 541 SRPINVIKFSTDEGQCWQTYTFTRDPIYFTGLASEPGARSMNISIWGFTESFLTSQWVSY 600
           S PI  +  S DEG+ W  Y+FT  P++  G+  EPG  ++ ++++G       S+W   
Sbjct: 604 SLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFGHFSH--RSEWQLV 661

Query: 601 TIDFKDILERNCEEKDYTIWLAHSTDPEDYEDGCILGYKEQFLRLRKSSVCQNGRDYVVT 660
            +D+K I +R C E+DY  W  HS       + CI+G K  + + +    C  G+ Y   
Sbjct: 662 KVDYKSIFDRRCAEEDYRPWQLHSQG-----EACIMGAKRIYKKRKSERKCMQGK-YAGA 715

Query: 661 KQPSICLCSLEDFLCDFGYYRPENDSKCVEQPELKGHDL-EFCLYGREEHLTTNGYRKIP 719
            +   C+C+  DF CD+GY R  N  +C+         L + C  G + +L + GYRK+ 
Sbjct: 716 MESEPCVCTEADFDCDYGYERHSN-GQCLPAFWFNPSSLSKDCSLG-QSYLNSTGYRKVV 773

Query: 720 GDKCQGGVNPVREVKDLK 737
            + C  GV      K  K
Sbjct: 774 SNNCTDGVREQYTAKPQK 791


>gi|61743973 SORCS receptor 1 isoform a [Homo sapiens]
          Length = 1168

 Score =  226 bits (576), Expect = 7e-59
 Identities = 169/678 (24%), Positives = 316/678 (46%), Gaps = 54/678 (7%)

Query: 82  EDEECGRVRDFVAKLANNTHQHVFDDLRGSVSLSWVGDSTGVILVLTTFHVPLVIMTFGQ 141
           + ++  R R    +L + T     D       + W G ++ VIL+LT  +    + +  +
Sbjct: 146 DPDKATRFRMEELRLTSTTFALTGDSAHNQAMVHWSGHNSSVILILTKLY-DYNLGSITE 204

Query: 142 SKLYRSEDYGKNFKDITDLINNTFIRTEFGMAIGPENSGKVVLTAEVSGGSRGGRIFRSS 201
           S L+RS DYG  ++ + D +    I +   + + P N  K++L  +    S    +  SS
Sbjct: 205 SSLWRSTDYGTTYEKLNDKVGLKTILSY--LYVCPTNKRKIMLLTDPEIESS---LLISS 259

Query: 202 DFAKNFVQTDLPFHPLTQMMYSPQNSDYLLALSTENGLWVSKNFGGKWEEIHKAVCLAKW 261
           D    + +  L F+ +  +++ P+  D++LA S +  L+ S  FG +W+ I + V   + 
Sbjct: 260 DEGATYQKYRLNFY-IQSLLFHPKQEDWILAYSQDQKLYSSAEFGRRWQLIQEGVVPNR- 317

Query: 262 GSDNTIFFTTYANGSCKADLGALELWRTSDLGKSFKTIGVKIY----------------S 305
                 F+ +    + + DL  LE  RT D    + T  ++                  S
Sbjct: 318 ------FYWSVMGSNKEPDLVHLEA-RTVDGHSHYLTCRMQNCTEANRNQPFPGYIDPDS 370

Query: 306 FGLGGRFLFASVMADKDTTRRIHVSTDQGDTWSMAQLPSVGQEQFYSILAANDDMVFMHV 365
             +   ++F  + +     R  +  + + + ++  +LP     +   +++ +++ VF  V
Sbjct: 371 LIVQDHYVFVQLTSGG---RPHYYVSYRRNAFAQMKLPKYALPKDMHVISTDENQVFAAV 427

Query: 366 DEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTTGGE----TDFTNVTSLRGVYITSVLSE 421
            E        ++ SD RG+ ++ +L+ ++ ++ G E     D   V  ++G+++ +    
Sbjct: 428 QEWNQNDTYNLYISDTRGVYFTLALE-NVQSSRGPEGNIMIDLYEVAGIKGMFLANK-KI 485

Query: 422 DNSIQTMITFDQGGRWTHLRKPENS-ECDATAKNKNECSLHIHASYSISQKLNVPMAPLS 480
           DN ++T IT+++G  W  L+ P+     D        CSLH+H   S +   +  +A  S
Sbjct: 486 DNQVKTFITYNKGRDWRLLQAPDTDLRGDPVHCLLPYCSLHLHLKVSENPYTSGIIA--S 543

Query: 481 EPNAVGIVIAHGSVGDAISVMVPDVYISDDGGYSWTKMLEGPHYYTILDSGGIIVAIEHS 540
           +  A  I++A G++G  +S     +++S D G +W ++ E  H    LD GG++VA++H+
Sbjct: 544 KDTAPSIIVASGNIGSELSDTDISMFVSSDAGNTWRQIFEEEHSVLYLDQGGVLVAMKHT 603

Query: 541 SRPINVIKFSTDEGQCWQTYTFTRDPIYFTGLASEPGARSMNISIWGFTESFLTSQWVSY 600
           S PI  +  S DEG+ W  Y+FT  P++  G+  EPG  ++ ++++G       S+W   
Sbjct: 604 SLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFGHFSH--RSEWQLV 661

Query: 601 TIDFKDILERNCEEKDYTIWLAHSTDPEDYEDGCILGYKEQFLRLRKSSVCQNGRDYVVT 660
            +D+K I +R C E+DY  W  HS       + CI+G K  + + +    C  G+ Y   
Sbjct: 662 KVDYKSIFDRRCAEEDYRPWQLHSQG-----EACIMGAKRIYKKRKSERKCMQGK-YAGA 715

Query: 661 KQPSICLCSLEDFLCDFGYYRPENDSKCVEQPELKGHDL-EFCLYGREEHLTTNGYRKIP 719
            +   C+C+  DF CD+GY R  N  +C+         L + C  G + +L + GYRK+ 
Sbjct: 716 MESEPCVCTEADFDCDYGYERHSN-GQCLPAFWFNPSSLSKDCSLG-QSYLNSTGYRKVV 773

Query: 720 GDKCQGGVNPVREVKDLK 737
            + C  GV      K  K
Sbjct: 774 SNNCTDGVREQYTAKPQK 791


>gi|18379346 VPS10 domain receptor protein SORCS 3 [Homo sapiens]
          Length = 1222

 Score =  215 bits (547), Expect = 2e-55
 Identities = 176/699 (25%), Positives = 333/699 (47%), Gaps = 62/699 (8%)

Query: 55  GVSWGLRAAAAGGAFPRGGRWRRSAPGEDEECGRVRDFVA---KLANNTHQHVFDDLRGS 111
           G +W    A A G+  RG R       E+ +  R     A   +L + +     D     
Sbjct: 143 GDAWA--TAPADGS--RGSRPLAKGSREEVKAPRAGGSAAEDLRLPSTSFALTGDSAHNQ 198

Query: 112 VSLSWVGDSTGVILVLTTFHVPLVIMTFGQSKLYRSEDYGKNFKDITDLINNTFIRTEFG 171
             + W G ++ VIL+LT  +    + +  +S L+RS DYG  ++ + D +    + +   
Sbjct: 199 AMVHWSGHNSSVILILTKLY-DFNLGSVTESSLWRSTDYGTTYEKLNDKVGLKTVLSY-- 255

Query: 172 MAIGPENSGKVVLTAEVSGGSRGGRIFRSSDFAKNFVQTDLPFHPLTQMMYSPQNSDYLL 231
           + + P N  K++L ++    S    I  SSD    + +  L F+ +  +++ P+  D++L
Sbjct: 256 LYVNPTNKRKIMLLSDPEMESS---ILISSDEGATYQKYRLTFY-IQSLLFHPKQEDWVL 311

Query: 232 ALSTENGLWVSKNFGGKWEEIHKAVCLAKWGSDNTIFFTTYANGSCKADLGALELWRTSD 291
           A S +  L+ S +FG +W+ +H+ +   +       F+ + A    +ADL  +E+ RT+D
Sbjct: 312 AYSLDQKLYSSMDFGRRWQLMHERITPNR-------FYWSVAGLDKEADLVHMEV-RTTD 363

Query: 292 LGKSFKTIGVKIYS----FGLGGRFLFASVMADKDTTRRIHVSTD---------QGDTWS 338
               + T  ++  +     G   R +  S +  +D    I V+T          + + ++
Sbjct: 364 GYAHYLTCRIQECAETTRSGPFARSIDISSLVVQDEYIFIQVTTSGRASYYVSYRREAFA 423

Query: 339 MAQLPSVGQEQFYSILAANDDMVFMHVDEPGDTGFGTIFTSDDRGIVYSKSLDRHLYTTT 398
             +LP     +   I++ +++ VF  V E        ++ SD RGI ++ +++ ++ ++ 
Sbjct: 424 QIKLPKYSLPKDMHIISTDENQVFAAVQEWNQNDTYNLYISDTRGIYFTLAME-NIKSSR 482

Query: 399 G--GET--DFTNVTSLRGVYITSVLSEDNSIQTMITFDQGGRWTHLRKPENSECDATAKN 454
           G  G    +   V  ++G+++ +    D+ ++T IT+++G  W  L+ P+     +    
Sbjct: 483 GLMGNIIIELYEVAGIKGIFLANK-KVDDQVKTYITYNKGRDWRLLQAPDVDLRGSPVHC 541

Query: 455 KNE-CSLHIHASYSISQKLNVPMAPLSEPNAVGIVIAHGSVGDAISVMVPDVYISDDGGY 513
               CSLH+H   S +   +  ++  S+  A G+V+A G++G  +S     V+IS DGG 
Sbjct: 542 LLPFCSLHLHLQLSENPYSSGRIS--SKETAPGLVVATGNIGPELSYTDIGVFISSDGGN 599

Query: 514 SWTKMLEGPHYYTILDSGGIIVAIEHSSRPINVIKFSTDEGQCWQTYTFTRDPIYFTGLA 573
           +W ++ +  +    LD GG +VA++H+  P+  +  S DEG  W  Y FT  P++  G  
Sbjct: 600 TWRQIFDEEYNVWFLDWGGALVAMKHTPLPVRHLWVSFDEGHSWDKYGFTSVPLFVDGAL 659

Query: 574 SEPGARSMNISIWGFTESFLTSQWVSYTIDFKDILERNCEEKDYTIW-LAHSTDPEDYED 632
            E G  +  ++++G     L S+W    +D+K I  R+C ++DY  W L +  +P     
Sbjct: 660 VEAGMETHIMTVFGHFS--LRSEWQLVKVDYKSIFSRHCTKEDYQTWHLLNQGEP----- 712

Query: 633 GCILGYKEQFLRLRKSSVCQNGRDYVVTKQPSICLCSLEDFLCDFGYYRPENDSKCVE-- 690
            C++G ++ F + +  + C  GRD+  +     C+C+  DF CD+GY R   +S+CV   
Sbjct: 713 -CVMGERKIFKKRKPGAQCALGRDHSGSVVSEPCVCANWDFECDYGYER-HGESQCVPAF 770

Query: 691 --QPELKGHDLEFCLYGREEHLTTNGYRKIPGDKCQGGV 727
              P     D   C  G + +L + GYR+I  + C  G+
Sbjct: 771 WYNPASPSKD---CSLG-QSYLNSTGYRRIVSNNCTDGL 805


>gi|24025682 F-box and leucine-rich repeat protein 16 [Homo
          sapiens]
          Length = 479

 Score = 34.3 bits (77), Expect = 0.49
 Identities = 25/72 (34%), Positives = 31/72 (43%), Gaps = 8/72 (11%)

Query: 15 PHGLGLLLLLQLLPPSTLSQDRLDAPPPPAAPLPRWSGPIGVSWGLRAAAAGG-AFPRGG 73
          P+GLG   + +  P +         PPPP  P P  + P+      RAA AGG   P GG
Sbjct: 27 PNGLGAASITKGTPAT--KNRPCQPPPPPTLPPPSLAAPLS-----RAALAGGPCTPAGG 79

Query: 74 RWRRSAPGEDEE 85
               APG   E
Sbjct: 80 PASALAPGHPAE 91


>gi|7705881 zinc finger protein 580 [Homo sapiens]
          Length = 172

 Score = 34.3 bits (77), Expect = 0.49
 Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 6/56 (10%)

Query: 21 LLLLQLLPPS--TLSQDRLDAPPPPAAPLPRWSGPIGVSWGLRAAAAGGAFPRGGR 74
          +LLL   PP   + S + +D PPP A P P+  GP        ++AAG   PR GR
Sbjct: 1  MLLLPPRPPHPRSSSPEAMDPPPPKAPPFPKAEGPSSTP----SSAAGPRPPRLGR 52


>gi|46361970 zinc finger protein 580 [Homo sapiens]
          Length = 172

 Score = 34.3 bits (77), Expect = 0.49
 Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 6/56 (10%)

Query: 21 LLLLQLLPPS--TLSQDRLDAPPPPAAPLPRWSGPIGVSWGLRAAAAGGAFPRGGR 74
          +LLL   PP   + S + +D PPP A P P+  GP        ++AAG   PR GR
Sbjct: 1  MLLLPPRPPHPRSSSPEAMDPPPPKAPPFPKAEGPSSTP----SSAAGPRPPRLGR 52


>gi|6631075 BCL2-associated athanogene 4 [Homo sapiens]
          Length = 457

 Score = 33.5 bits (75), Expect = 0.83
 Identities = 16/48 (33%), Positives = 20/48 (41%)

Query: 28 PPSTLSQDRLDAPPPPAAPLPRWSGPIGVSWGLRAAAAGGAFPRGGRW 75
          PP  L   R + P PP +   R  GP   +W        G +P GG W
Sbjct: 32 PPPPLYPLRPEPPQPPISWRVRGGGPAETTWLGEGGGGDGYYPSGGAW 79


>gi|169172087 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 278

 Score = 33.1 bits (74), Expect = 1.1
 Identities = 18/50 (36%), Positives = 21/50 (42%), Gaps = 11/50 (22%)

Query: 37  LDAPPPPAAPLPRWSGPIGVSWGLRAAA-----------AGGAFPRGGRW 75
           L++P     PLPR  GP G+ W L  AA            G   P G RW
Sbjct: 150 LESPAAAQDPLPRHVGPSGLGWSLEPAARVLSGLLVGAGVGPRLPCGARW 199


>gi|113419362 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 248

 Score = 33.1 bits (74), Expect = 1.1
 Identities = 18/50 (36%), Positives = 21/50 (42%), Gaps = 11/50 (22%)

Query: 37  LDAPPPPAAPLPRWSGPIGVSWGLRAAA-----------AGGAFPRGGRW 75
           L++P     PLPR  GP G+ W L  AA            G   P G RW
Sbjct: 120 LESPAAAQDPLPRHVGPSGLGWSLEPAARVLSGLLVGAGVGPRLPCGARW 169


>gi|113418886 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 248

 Score = 33.1 bits (74), Expect = 1.1
 Identities = 18/50 (36%), Positives = 21/50 (42%), Gaps = 11/50 (22%)

Query: 37  LDAPPPPAAPLPRWSGPIGVSWGLRAAA-----------AGGAFPRGGRW 75
           L++P     PLPR  GP G+ W L  AA            G   P G RW
Sbjct: 120 LESPAAAQDPLPRHVGPSGLGWSLEPAARVLSGLLVGAGVGPRLPCGARW 169


>gi|113419893 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 248

 Score = 33.1 bits (74), Expect = 1.1
 Identities = 18/50 (36%), Positives = 21/50 (42%), Gaps = 11/50 (22%)

Query: 37  LDAPPPPAAPLPRWSGPIGVSWGLRAAA-----------AGGAFPRGGRW 75
           L++P     PLPR  GP G+ W L  AA            G   P G RW
Sbjct: 120 LESPAAAQDPLPRHVGPSGLGWSLEPAARVLSGLLVGAGVGPRLPCGARW 169


>gi|33239445 eukaryotic translation initiation factor 3, subunit 9
           eta, 116kDa [Homo sapiens]
          Length = 814

 Score = 32.3 bits (72), Expect = 1.9
 Identities = 21/72 (29%), Positives = 30/72 (41%), Gaps = 12/72 (16%)

Query: 260 KWGSDNTIFFTTYANGSCKADLGALELWRTSDLG----KSFKTIGVKIYSFGLGGRFLFA 315
           KW  D   F         +  L  L ++ T  +G    KS K  G+K +S+  GG  +  
Sbjct: 430 KWSHDGKFF--------ARMTLDTLSIYETPSMGLLDKKSLKISGIKDFSWSPGGNIIAF 481

Query: 316 SVMADKDTTRRI 327
            V  DKD   R+
Sbjct: 482 WVPEDKDIPARV 493


>gi|83367072 eukaryotic translation initiation factor 3, subunit 9
           eta, 116kDa [Homo sapiens]
          Length = 814

 Score = 32.3 bits (72), Expect = 1.9
 Identities = 21/72 (29%), Positives = 30/72 (41%), Gaps = 12/72 (16%)

Query: 260 KWGSDNTIFFTTYANGSCKADLGALELWRTSDLG----KSFKTIGVKIYSFGLGGRFLFA 315
           KW  D   F         +  L  L ++ T  +G    KS K  G+K +S+  GG  +  
Sbjct: 430 KWSHDGKFF--------ARMTLDTLSIYETPSMGLLDKKSLKISGIKDFSWSPGGNIIAF 481

Query: 316 SVMADKDTTRRI 327
            V  DKD   R+
Sbjct: 482 WVPEDKDIPARV 493


>gi|148236531 hypothetical protein LOC339779 [Homo sapiens]
          Length = 412

 Score = 32.3 bits (72), Expect = 1.9
 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 4/48 (8%)

Query: 5  WGAADGLSRWPHGLGLLLLLQLLPPS----TLSQDRLDAPPPPAAPLP 48
          WG +  +   PH L  L   Q LPPS    + +Q R  + PPPA+P P
Sbjct: 22 WGFSQLVDSSPHNLQPLSPHQGLPPSQPPFSSTQSRRPSSPPPASPSP 69


>gi|18426904 Werner helicase interacting protein isoform 2 [Homo
           sapiens]
          Length = 640

 Score = 31.6 bits (70), Expect = 3.2
 Identities = 25/65 (38%), Positives = 31/65 (47%), Gaps = 12/65 (18%)

Query: 31  TLSQDRLDAPPPPAA-------PLPRWSGPIGVSWGLR---AAAAGGAFPRGGRWRRSAP 80
           T S++  DAPP P+        P+ R S P     G R   AAAAG A PR   W  +  
Sbjct: 105 TESRESYDAPPTPSGARLIPDFPVARSSSPGRKGSGKRPAAAAAAGSASPRS--WDEAEA 162

Query: 81  GEDEE 85
            E+EE
Sbjct: 163 QEEEE 167


>gi|18426902 Werner helicase interacting protein isoform 1 [Homo
           sapiens]
          Length = 665

 Score = 31.6 bits (70), Expect = 3.2
 Identities = 25/65 (38%), Positives = 31/65 (47%), Gaps = 12/65 (18%)

Query: 31  TLSQDRLDAPPPPAA-------PLPRWSGPIGVSWGLR---AAAAGGAFPRGGRWRRSAP 80
           T S++  DAPP P+        P+ R S P     G R   AAAAG A PR   W  +  
Sbjct: 105 TESRESYDAPPTPSGARLIPDFPVARSSSPGRKGSGKRPAAAAAAGSASPRS--WDEAEA 162

Query: 81  GEDEE 85
            E+EE
Sbjct: 163 QEEEE 167


>gi|16753221 cadherin 22 precursor [Homo sapiens]
          Length = 828

 Score = 31.6 bits (70), Expect = 3.2
 Identities = 36/124 (29%), Positives = 51/124 (41%), Gaps = 27/124 (21%)

Query: 15  PHGLGL---------LLLLQLLPPSTLSQDRLDA--PPPPAAPLPRWSGPIGVSWGLRAA 63
           P G GL         LLLL LLPP      RL A   P P+AP  R  G +G        
Sbjct: 5   PEGRGLRAGVALSPALLLLLLLPPPPTLLGRLWAAGTPSPSAPGARQDGALG-------- 56

Query: 64  AAGGAFPRGGRWRRSAPGEDEECGRVRDFVAKLANNTHQHVFDDLRGSVSLSWVGDSTGV 123
              G   RG  W +    E E  G    +V K+ +++     D+  G++  +  G+  G 
Sbjct: 57  --AGRVKRGWVWNQFFVVE-EYTGTEPLYVGKIHSDS-----DEGDGAIKYTISGEGAGT 108

Query: 124 ILVL 127
           I ++
Sbjct: 109 IFLI 112


>gi|113426467 PREDICTED: UPF0607 protein ENSP00000381418-like [Homo
           sapiens]
          Length = 415

 Score = 31.2 bits (69), Expect = 4.1
 Identities = 20/43 (46%), Positives = 21/43 (48%)

Query: 4   PWGAADGLSRWPHGLGLLLLLQLLPPSTLSQDRLDAPPPPAAP 46
           P  AA   SR     G LL LQL PP  L  DR + PPP   P
Sbjct: 313 PPRAAGHSSRKRKLSGPLLQLQLTPPLQLRWDRNEGPPPAKLP 355


>gi|21217561 Shaw-related voltage-gated potassium channel protein
          2 isoform KV3.2a [Homo sapiens]
          Length = 613

 Score = 31.2 bits (69), Expect = 4.1
 Identities = 22/61 (36%), Positives = 25/61 (40%), Gaps = 3/61 (4%)

Query: 17 GLGLLLLLQLLPPS---TLSQDRLDAPPPPAAPLPRWSGPIGVSWGLRAAAAGGAFPRGG 73
          G  L LL    PP    T + D+L   PPP +P PR         G     AG    RGG
Sbjct: 31 GTRLALLASSEPPGDCLTTAGDKLQPSPPPLSPPPRAPPLSPGPGGCFEGGAGNCSSRGG 90

Query: 74 R 74
          R
Sbjct: 91 R 91


>gi|21217563 Shaw-related voltage-gated potassium channel protein
          2 isoform KV3.2b [Homo sapiens]
          Length = 638

 Score = 31.2 bits (69), Expect = 4.1
 Identities = 22/61 (36%), Positives = 25/61 (40%), Gaps = 3/61 (4%)

Query: 17 GLGLLLLLQLLPPS---TLSQDRLDAPPPPAAPLPRWSGPIGVSWGLRAAAAGGAFPRGG 73
          G  L LL    PP    T + D+L   PPP +P PR         G     AG    RGG
Sbjct: 31 GTRLALLASSEPPGDCLTTAGDKLQPSPPPLSPPPRAPPLSPGPGGCFEGGAGNCSSRGG 90

Query: 74 R 74
          R
Sbjct: 91 R 91


>gi|24497458 Shaw-related voltage-gated potassium channel protein
          2 isoform KV3.2c [Homo sapiens]
          Length = 558

 Score = 31.2 bits (69), Expect = 4.1
 Identities = 22/61 (36%), Positives = 25/61 (40%), Gaps = 3/61 (4%)

Query: 17 GLGLLLLLQLLPPS---TLSQDRLDAPPPPAAPLPRWSGPIGVSWGLRAAAAGGAFPRGG 73
          G  L LL    PP    T + D+L   PPP +P PR         G     AG    RGG
Sbjct: 31 GTRLALLASSEPPGDCLTTAGDKLQPSPPPLSPPPRAPPLSPGPGGCFEGGAGNCSSRGG 90

Query: 74 R 74
          R
Sbjct: 91 R 91


>gi|113426153 PREDICTED: UPF0607 protein ENSP00000381418-like [Homo
           sapiens]
          Length = 415

 Score = 30.8 bits (68), Expect = 5.4
 Identities = 20/43 (46%), Positives = 21/43 (48%)

Query: 4   PWGAADGLSRWPHGLGLLLLLQLLPPSTLSQDRLDAPPPPAAP 46
           P  AA   SR     G LL LQL PP  L  DR + PPP   P
Sbjct: 313 PPRAAGHSSRKRKLSGPLLQLQLTPPLQLRWDRDEGPPPAKLP 355


>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
          Length = 2803

 Score = 30.8 bits (68), Expect = 5.4
 Identities = 25/75 (33%), Positives = 28/75 (37%), Gaps = 18/75 (24%)

Query: 27   LPPSTLSQDRLDAPPPPAAPLPRWSGPIGVSWGL-------------RAAAAGGAFPRGG 73
            LPP+ LS       P P  P P    P   SWG               A   GG +   G
Sbjct: 1852 LPPAPLSP-----APGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLG 1906

Query: 74   RWRRSAPGEDEECGR 88
            +  R A GE EE GR
Sbjct: 1907 KDYRKAEGEREEEGR 1921


>gi|225735557 nuclear factor erythroid 2-like 3 [Homo sapiens]
          Length = 694

 Score = 30.8 bits (68), Expect = 5.4
 Identities = 34/99 (34%), Positives = 40/99 (40%), Gaps = 15/99 (15%)

Query: 1  MERPWGAADGLSRWPHGLGL------LLLLQLLPPSTLSQDR---LDAPPPPAAPLPRWS 51
          ++R W A  GL      L L      L L  LLPP TL QD    L  P   A  L  +S
Sbjct: 4  LKRWWSAGGGLLHLTLLLSLAGLRVDLDLYLLLPPPTLLQDELLFLGGPASSAYALSPFS 63

Query: 52 GPIGVSWGLRAAAAGGAFPRGGRWRRSAPGEDEECGRVR 90
             G  WG     AG   P+G     +AP E +    VR
Sbjct: 64 ASGG--WG----RAGHLHPKGRELDPAAPPEGQLLREVR 96


>gi|226053185 paternally expressed 3 isoform 3 [Homo sapiens]
          Length = 1464

 Score = 30.4 bits (67), Expect = 7.1
 Identities = 18/75 (24%), Positives = 35/75 (46%), Gaps = 3/75 (4%)

Query: 143  KLYRSEDYGKNFKDITDLINNTFIRTEFGMAIGPENSGKVVLTAEVSGGSR---GGRIFR 199
            K+Y  ED G  F D+TDL ++  + +   +    E +  V+ T  +S   R   G +++ 
Sbjct: 981  KIYECEDCGLGFVDLTDLTDHQKVHSRKCLVDSREYTHSVIHTHSISEYQRDYTGEQLYE 1040

Query: 200  SSDFAKNFVQTDLPF 214
                 ++F+ +   F
Sbjct: 1041 CPKCGESFIHSSFLF 1055


>gi|226053169 paternally expressed 3 isoform 1 [Homo sapiens]
          Length = 1588

 Score = 30.4 bits (67), Expect = 7.1
 Identities = 18/75 (24%), Positives = 35/75 (46%), Gaps = 3/75 (4%)

Query: 143  KLYRSEDYGKNFKDITDLINNTFIRTEFGMAIGPENSGKVVLTAEVSGGSR---GGRIFR 199
            K+Y  ED G  F D+TDL ++  + +   +    E +  V+ T  +S   R   G +++ 
Sbjct: 1105 KIYECEDCGLGFVDLTDLTDHQKVHSRKCLVDSREYTHSVIHTHSISEYQRDYTGEQLYE 1164

Query: 200  SSDFAKNFVQTDLPF 214
                 ++F+ +   F
Sbjct: 1165 CPKCGESFIHSSFLF 1179


>gi|226053148 paternally expressed 3 isoform 2 [Homo sapiens]
          Length = 1462

 Score = 30.4 bits (67), Expect = 7.1
 Identities = 18/75 (24%), Positives = 35/75 (46%), Gaps = 3/75 (4%)

Query: 143  KLYRSEDYGKNFKDITDLINNTFIRTEFGMAIGPENSGKVVLTAEVSGGSR---GGRIFR 199
            K+Y  ED G  F D+TDL ++  + +   +    E +  V+ T  +S   R   G +++ 
Sbjct: 979  KIYECEDCGLGFVDLTDLTDHQKVHSRKCLVDSREYTHSVIHTHSISEYQRDYTGEQLYE 1038

Query: 200  SSDFAKNFVQTDLPF 214
                 ++F+ +   F
Sbjct: 1039 CPKCGESFIHSSFLF 1053


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,673,932
Number of Sequences: 37866
Number of extensions: 1686932
Number of successful extensions: 5440
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 5341
Number of HSP's gapped (non-prelim): 68
length of query: 831
length of database: 18,247,518
effective HSP length: 111
effective length of query: 720
effective length of database: 14,044,392
effective search space: 10111962240
effective search space used: 10111962240
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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