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Search of human proteins with 169210053
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
(185 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] 367 e-102
gi|17975763 myelin transcription factor 1 [Homo sapiens] 82 3e-16
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 72 2e-13
gi|221219020 NYD-SP11 protein [Homo sapiens] 72 4e-13
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 66 1e-11
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 66 1e-11
gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ... 66 1e-11
gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo ... 66 1e-11
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 66 1e-11
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 66 1e-11
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 66 1e-11
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 66 1e-11
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 66 1e-11
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 66 1e-11
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 66 1e-11
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] 65 3e-11
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 65 3e-11
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 65 3e-11
gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Hom... 64 7e-11
gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Hom... 64 7e-11
gi|28274705 family with sequence similarity 9, member A [Homo sa... 64 7e-11
gi|22749303 hypothetical protein LOC196477 [Homo sapiens] 63 1e-10
gi|21735415 centromere protein B [Homo sapiens] 63 2e-10
gi|55741661 hypothetical protein LOC57653 [Homo sapiens] 62 3e-10
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 62 3e-10
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 62 4e-10
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi... 61 5e-10
gi|21735569 claspin [Homo sapiens] 61 5e-10
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 61 5e-10
gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo ... 61 6e-10
>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
Length = 185
Score = 367 bits (943), Expect = e-102
Identities = 185/185 (100%), Positives = 185/185 (100%)
Query: 1 MAARLKVLGLRKPPPSHATGVSTQSFQILGREGWRVKPAHTLLAMTSQRNKELRPSTCLE 60
MAARLKVLGLRKPPPSHATGVSTQSFQILGREGWRVKPAHTLLAMTSQRNKELRPSTCLE
Sbjct: 1 MAARLKVLGLRKPPPSHATGVSTQSFQILGREGWRVKPAHTLLAMTSQRNKELRPSTCLE 60
Query: 61 VEEKWLQRWAVGLPVKDSGVSQAKIWGKNDLSAGNRLSVARTAALVAEECSAQQGLPVEE 120
VEEKWLQRWAVGLPVKDSGVSQAKIWGKNDLSAGNRLSVARTAALVAEECSAQQGLPVEE
Sbjct: 61 VEEKWLQRWAVGLPVKDSGVSQAKIWGKNDLSAGNRLSVARTAALVAEECSAQQGLPVEE 120
Query: 121 EEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQ 180
EEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQ
Sbjct: 121 EEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQ 180
Query: 181 RTQYL 185
RTQYL
Sbjct: 181 RTQYL 185
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 82.0 bits (201), Expect = 3e-16
Identities = 40/62 (64%), Positives = 53/62 (85%)
Query: 107 AEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKM 166
+EE S Q+G+ EEE EEEEEE EEEE++EE+EE+EEEEE+EEE+EE+EEEEE+E ++
Sbjct: 245 SEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 304
Query: 167 EE 168
EE
Sbjct: 305 EE 306
Score = 63.9 bits (154), Expect = 7e-11
Identities = 34/64 (53%), Positives = 45/64 (70%)
Query: 93 AGNRLSVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEK 152
A + S + L EE ++ EEEE +EEEEE EEEE+EEE+EE+EEEEE+EEE+
Sbjct: 243 AASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEE 302
Query: 153 EEDE 156
EE+E
Sbjct: 303 EEEE 306
Score = 62.8 bits (151), Expect = 2e-10
Identities = 30/65 (46%), Positives = 47/65 (72%)
Query: 114 QGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEE 173
Q L E +++ + E+E+E+EE+EEEEE+E+E+EE+EEEEE+E ++ EEE+ EE
Sbjct: 238 QSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 297
Query: 174 EIDTE 178
E + E
Sbjct: 298 EEEEE 302
Score = 60.5 bits (145), Expect = 8e-10
Identities = 39/97 (40%), Positives = 55/97 (56%), Gaps = 21/97 (21%)
Query: 103 AALVAEECSAQQGLPVEEEEVEE-----------------EEEEVEEEEKEE----EKEE 141
AA A ++GL ++ E+ EE E+ EE K++ +EE
Sbjct: 201 AAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEE 260
Query: 142 DEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
DEEEEE+EEE+EEDEEEEE+E ++ EEE+ EEE + E
Sbjct: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 297
Score = 58.5 bits (140), Expect = 3e-09
Identities = 29/67 (43%), Positives = 45/67 (67%)
Query: 112 AQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKV 171
+Q P E+ EE ++ E+E++EEEEE+EEE+E++EEEEE+E ++ EEE+
Sbjct: 232 SQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEE 291
Query: 172 EEEIDTE 178
EEE + E
Sbjct: 292 EEEEEEE 298
Score = 42.7 bits (99), Expect = 2e-04
Identities = 37/155 (23%), Positives = 70/155 (45%), Gaps = 21/155 (13%)
Query: 30 GREGWRVKP--AHTLLAMTSQRNKELRPSTCLEV--EEKWLQRWAVGLPVKDSGVSQAKI 85
G +G ++P A ++ +T++R+++L P + + EE Q+ + +D + +
Sbjct: 210 GEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEE 269
Query: 86 WGKNDLSAGNRLSVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEE 145
+ D EE ++ EEEE EEEEEE EEEE+EEE+ +
Sbjct: 270 EEEED-----------------EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVI 312
Query: 146 EEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQ 180
+++ ++ E G + K E + E++
Sbjct: 313 FQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVR 347
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 72.4 bits (176), Expect = 2e-13
Identities = 40/62 (64%), Positives = 49/62 (79%), Gaps = 2/62 (3%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEE--EEKEEEKEEDEEEEEKEGKKMEEEKVEEEID 176
EEEE EEEEEE EEEE EE+EEDEEE EE+EEE+EE EEE E+E ++EEE+ EE+ +
Sbjct: 893 EEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEE 952
Query: 177 TE 178
E
Sbjct: 953 EE 954
Score = 70.1 bits (170), Expect = 1e-12
Identities = 36/60 (60%), Positives = 48/60 (80%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
EEEE EEEEEE EEEE+EEE++ +EEEE++EE EE+EEEEE+ ++ EEE+ E E + E
Sbjct: 888 EEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEE 947
Score = 69.3 bits (168), Expect = 2e-12
Identities = 42/77 (54%), Positives = 54/77 (70%), Gaps = 6/77 (7%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEE---KEEDEEEEEKEEEKEEDE---EEEEK 161
EE ++ EEEE EEEEE+ EEEE++EE +EE+EEEEE EEE EE+E EEEE+
Sbjct: 888 EEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEE 947
Query: 162 EGKKMEEEKVEEEIDTE 178
E + EEE++EE D E
Sbjct: 948 EEDEEEEEELEEVEDLE 964
Score = 68.2 bits (165), Expect = 4e-12
Identities = 34/61 (55%), Positives = 47/61 (77%)
Query: 118 VEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDT 177
+ + EEEEEE EEEE+EEE+EE+E+ EE+EE++EE EEEE+E ++ EEE EEE +
Sbjct: 883 INSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGEL 942
Query: 178 E 178
E
Sbjct: 943 E 943
Score = 66.6 bits (161), Expect = 1e-11
Identities = 35/67 (52%), Positives = 50/67 (74%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
EEEE EEEEEE + EE+EE++EE EEEE+EEE+ E+E EEE+ + EEE+ +EE + E
Sbjct: 897 EEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEE 956
Query: 179 IQRTQYL 185
++ + L
Sbjct: 957 LEEVEDL 963
Score = 65.9 bits (159), Expect = 2e-11
Identities = 37/77 (48%), Positives = 52/77 (67%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKME 167
EE ++ EEEE EEEE+ EEEE EEE E+EEEEE+E E+E +EEE E E ++ E
Sbjct: 889 EEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEE 948
Query: 168 EEKVEEEIDTEIQRTQY 184
E++ EEE E++ ++
Sbjct: 949 EDEEEEEELEEVEDLEF 965
Score = 52.8 bits (125), Expect = 2e-07
Identities = 31/62 (50%), Positives = 42/62 (67%), Gaps = 1/62 (1%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKE-EEKEEDEEEEEKEEEKEEDEEEEEKEGKKM 166
EE ++ EEEE EE EEE EEEE E EE+EE+E+EEE+EE +E ++ E G ++
Sbjct: 913 EEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEV 972
Query: 167 EE 168
EE
Sbjct: 973 EE 974
Score = 46.2 bits (108), Expect = 2e-05
Identities = 24/44 (54%), Positives = 32/44 (72%)
Query: 120 EEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEG 163
EEE EEEE E+EEEE+EE++EE+EE EE E+ + E +EG
Sbjct: 932 EEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEG 975
Score = 33.9 bits (76), Expect = 0.082
Identities = 21/52 (40%), Positives = 28/52 (53%)
Query: 105 LVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDE 156
LV EE SA L EE E ++ + E EE+ E E E E +EKE+D+
Sbjct: 1053 LVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDD 1104
Score = 31.6 bits (70), Expect = 0.41
Identities = 14/34 (41%), Positives = 24/34 (70%)
Query: 151 EKEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQY 184
++EE+EEEEE+E ++ EEE+ E+ + E +Y
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEY 920
Score = 29.6 bits (65), Expect = 1.5
Identities = 22/85 (25%), Positives = 38/85 (44%), Gaps = 11/85 (12%)
Query: 100 ARTAALVAEECSAQQGL-----------PVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEK 148
A TA +A E QG P +E VEEE +EE ++ ++ +
Sbjct: 1020 ADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPP 1079
Query: 149 EEEKEEDEEEEEKEGKKMEEEKVEE 173
E E+E E E E + ++E++ ++
Sbjct: 1080 PETPAEEEMETETEAEALQEKEQDD 1104
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 71.6 bits (174), Expect = 4e-13
Identities = 38/74 (51%), Positives = 54/74 (72%), Gaps = 3/74 (4%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEE---EKEEEKEEDEEEEEKEEEKEEDEEEEEKEGK 164
+E Q+ L EEEE EEEEE EEE E+EEE++E+EE EEK+ EKEE+E++++K+ K
Sbjct: 2235 DELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEK 2294
Query: 165 KMEEEKVEEEIDTE 178
K EE + +EE+ E
Sbjct: 2295 KKEEVQEKEEVFEE 2308
Score = 62.4 bits (150), Expect = 2e-10
Identities = 33/60 (55%), Positives = 49/60 (81%), Gaps = 2/60 (3%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
EEEEV EEEEE +EEE+ EEK+ ++EEEEK+++K+E ++EE +E +++ EEK EEI +E
Sbjct: 2258 EEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEK--EEIMSE 2315
Score = 60.5 bits (145), Expect = 8e-10
Identities = 33/65 (50%), Positives = 47/65 (72%), Gaps = 5/65 (7%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEK-----VEE 173
EE++VE+EEEE ++++KE++KEE +E+EE EEKEE EEE E EEE+ +EE
Sbjct: 2276 EEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEE 2335
Query: 174 EIDTE 178
E+D E
Sbjct: 2336 EVDRE 2340
Score = 58.5 bits (140), Expect = 3e-09
Identities = 32/77 (41%), Positives = 51/77 (66%), Gaps = 1/77 (1%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEE-EEKEEEKEEDEEEEEKEGKKM 166
E S + ++E E +E EEEE+EEE+E +EEE E+EEE++E+EE EEK+ +K
Sbjct: 2224 EHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKE 2283
Query: 167 EEEKVEEEIDTEIQRTQ 183
EEEK +++ + + + Q
Sbjct: 2284 EEEKKKKKKEKKKEEVQ 2300
Score = 56.2 bits (134), Expect = 2e-08
Identities = 30/69 (43%), Positives = 45/69 (65%), Gaps = 2/69 (2%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEE--EEKEGKK 165
+E +++ E E + +E E+ E EEE+E +EEEE +EEE E+EEE EE+EG++
Sbjct: 2218 DEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEE 2277
Query: 166 MEEEKVEEE 174
+ EK EEE
Sbjct: 2278 KQVEKEEEE 2286
Score = 55.8 bits (133), Expect = 2e-08
Identities = 31/73 (42%), Positives = 47/73 (64%), Gaps = 2/73 (2%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEE--EEKEGKK 165
E+ S+Q EE EE E + +E +++E EEEEE+EEE+E +EEE EE+E +K
Sbjct: 2211 EKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERK 2270
Query: 166 MEEEKVEEEIDTE 178
EEE E++++ E
Sbjct: 2271 EEEEGEEKQVEKE 2283
Score = 55.1 bits (131), Expect = 3e-08
Identities = 30/70 (42%), Positives = 50/70 (71%), Gaps = 1/70 (1%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKME 167
EE ++ V EEE E +EEE E EEK+ EKEE+E++++K+E+K+E+ +E+E+ ++ E
Sbjct: 2252 EEEEEREEEEVREEEEERKEEE-EGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKE 2310
Query: 168 EEKVEEEIDT 177
E EEE ++
Sbjct: 2311 EIMSEEETES 2320
Score = 50.8 bits (120), Expect = 6e-07
Identities = 32/63 (50%), Positives = 41/63 (65%), Gaps = 4/63 (6%)
Query: 121 EEVEEEE---EEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDT 177
+EVE EE EE+E E EK+E EE EEE+EE+EE EE+E ++ EEE+ EEE
Sbjct: 2218 DEVESEEHFSEEMESLLDELEKQESLSSEE-EEEREEEEEREEEEVREEEEERKEEEEGE 2276
Query: 178 EIQ 180
E Q
Sbjct: 2277 EKQ 2279
Score = 43.9 bits (102), Expect = 8e-05
Identities = 24/56 (42%), Positives = 35/56 (62%), Gaps = 1/56 (1%)
Query: 120 EEEVEEEEEEVEEEEK-EEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEE 174
+E+ + +EVE EE EE E +E EK+E +EEEE +E ++ EEE+V EE
Sbjct: 2210 KEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREE 2265
Score = 43.5 bits (101), Expect = 1e-04
Identities = 34/89 (38%), Positives = 50/89 (56%), Gaps = 11/89 (12%)
Query: 108 EECSAQQGLPVEEEEV-----EEEEEEVEE-EEKEEEKEEDEEEEEKEEEKEEDEEE--- 158
EE ++ + EEEE E+++EEV+E EE EEKEE EEE E +E+EEE
Sbjct: 2272 EEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESC 2331
Query: 159 --EEKEGKKMEEEKVEEEIDTEIQRTQYL 185
EE+ ++ E K E++ + QR + L
Sbjct: 2332 SLEEEVDREKEILKKEKQFKLQEQRRKSL 2360
Score = 41.6 bits (96), Expect = 4e-04
Identities = 29/89 (32%), Positives = 52/89 (58%), Gaps = 12/89 (13%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEV---------EEEEKEEEKEE--DEEEEEKEEEKEEDE 156
EE + ++G VEE++ EEEE EEE K ++EE +E+E+ + KE+
Sbjct: 1733 EELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMP 1792
Query: 157 EEEEKEGKKMEEEKVEEEIDTEIQRTQYL 185
EEEE+ G+K E+ +E+++ +R +++
Sbjct: 1793 EEEERLGRK-REQLIEKKMKLAQKRERWI 1820
Score = 40.8 bits (94), Expect = 7e-04
Identities = 32/91 (35%), Positives = 50/91 (54%), Gaps = 8/91 (8%)
Query: 103 AALVAEECSAQQGLPVEEEEVEEEEEEVE---EEEKEEEKEEDEEEEEKEEEKEEDEEEE 159
A V E +Q L +E+E+ +E EE+E EE +E+E ++EE + EEK++ EEE
Sbjct: 1694 AQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEE 1753
Query: 160 E-----KEGKKMEEEKVEEEIDTEIQRTQYL 185
E +E EE K+ +E + IQ + L
Sbjct: 1754 EALAWQREKLSEEETKLAQEEELLIQEKEKL 1784
Score = 36.6 bits (83), Expect = 0.013
Identities = 26/63 (41%), Positives = 36/63 (57%), Gaps = 7/63 (11%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEE----DEEEEEKEEEKEEDEEE---EEKEGKKMEEEKV 171
EEE +EE + VEE++K E+EE E+ +EE K EEE +EKE +EK+
Sbjct: 1732 EEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKM 1791
Query: 172 EEE 174
EE
Sbjct: 1792 PEE 1794
Score = 35.4 bits (80), Expect = 0.028
Identities = 26/89 (29%), Positives = 46/89 (51%), Gaps = 2/89 (2%)
Query: 86 WGKNDLSAGNRLSVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEE 145
W K L +L A L EE Q+ ++ EE ++ E + + +E++ +DEEE
Sbjct: 1485 WEKRLLQEEEKLHQAGEK-LSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEE 1543
Query: 146 EEKEEEKEEDEEEEEKEGKKMEEEKVEEE 174
EEE + EE+E++ + E+ ++EE
Sbjct: 1544 VTLEEEVSREGEEKEQQVTE-EQRHIQEE 1571
Score = 35.4 bits (80), Expect = 0.028
Identities = 19/59 (32%), Positives = 32/59 (54%), Gaps = 4/59 (6%)
Query: 120 EEEVEEEEEEVEEEEKEEEKEEDEEEE----EKEEEKEEDEEEEEKEGKKMEEEKVEEE 174
EEEV E EE E++ EE++ EE + ++ + E + +E+ EEEK+ +E
Sbjct: 1547 EEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQE 1605
Score = 34.3 bits (77), Expect = 0.063
Identities = 16/56 (28%), Positives = 30/56 (53%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEE 174
+E++V EE+ ++EE K EK+ +EE + +E+E EE ++ +E
Sbjct: 1557 KEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQE 1612
Score = 33.9 bits (76), Expect = 0.082
Identities = 17/68 (25%), Positives = 39/68 (57%)
Query: 103 AALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKE 162
A + + A++ EE ++ +EEE++ +EE++ +EE + + + ++D E + E
Sbjct: 1575 ARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAE 1634
Query: 163 GKKMEEEK 170
GK ++E+
Sbjct: 1635 GKFAQKEE 1642
Score = 32.7 bits (73), Expect = 0.18
Identities = 17/58 (29%), Positives = 34/58 (58%), Gaps = 2/58 (3%)
Query: 119 EEEEVEEEEEEVEEE--EKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEE 174
E++ +EEE +EEE + EEKE+ EE++ ++E ++ + E+++ +EE
Sbjct: 1535 EQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEE 1592
Score = 32.3 bits (72), Expect = 0.24
Identities = 26/75 (34%), Positives = 38/75 (50%), Gaps = 14/75 (18%)
Query: 118 VEEEEVE-------EEEEEVEEEEKEEEK-----EEDEEEEEKEEEKEE--DEEEEEKEG 163
+EEEEV + +E + +K +EK +E E EE EE E DE E+++
Sbjct: 2184 IEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESL 2243
Query: 164 KKMEEEKVEEEIDTE 178
EEE+ EEE + E
Sbjct: 2244 SSEEEEEREEEEERE 2258
Score = 32.0 bits (71), Expect = 0.31
Identities = 20/62 (32%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEK-EEEKEEDEEEEEKEEEKEEDEEEEEKEGKKM 166
EE ++ + EEE E +E EEEE E+E D E+E ++EK+ +E+ ++ +
Sbjct: 2303 EEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRG 2362
Query: 167 EE 168
E
Sbjct: 2363 RE 2364
Score = 31.6 bits (70), Expect = 0.41
Identities = 19/63 (30%), Positives = 34/63 (53%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKME 167
EE Q P + + ++E +V + ++E KEE + EE EE +E+ ++EGK +
Sbjct: 1391 EEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLVM 1450
Query: 168 EEK 170
E+
Sbjct: 1451 IER 1453
Score = 29.3 bits (64), Expect = 2.0
Identities = 18/72 (25%), Positives = 36/72 (50%), Gaps = 6/72 (8%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEE------KEEEKEEDEEEEEKEEEKEEDEEEEEK 161
EE +++G E++ EE+ EE + K E+ +EE++ +EE++ +E+
Sbjct: 1547 EEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEE 1606
Query: 162 EGKKMEEEKVEE 173
EE K+ +
Sbjct: 1607 RQLAQEERKLAQ 1618
Score = 29.3 bits (64), Expect = 2.0
Identities = 15/57 (26%), Positives = 29/57 (50%)
Query: 118 VEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEE 174
V E E+E++ EE+ +E+ + K E+ +EE++ + EE+ +EE
Sbjct: 1550 VSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEE 1606
Score = 29.3 bits (64), Expect = 2.0
Identities = 20/79 (25%), Positives = 42/79 (53%), Gaps = 2/79 (2%)
Query: 109 ECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEE 168
E + +G ++EE + E +E E+ ++ ++ +K E+ +EE+ K+G K+ E
Sbjct: 1629 EMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAE 1688
Query: 169 EK--VEEEIDTEIQRTQYL 185
K + ++++ QR Q L
Sbjct: 1689 VKNILAQKVEELPQREQNL 1707
Score = 28.9 bits (63), Expect = 2.6
Identities = 21/82 (25%), Positives = 44/82 (53%), Gaps = 3/82 (3%)
Query: 107 AEECSAQQG--LPVEEEEVEEEEEEV-EEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEG 163
AE+ AQ+ L EEE++ +EE ++ +EE K + ++++E + E + +++E
Sbjct: 1584 AEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEET 1643
Query: 164 KKMEEEKVEEEIDTEIQRTQYL 185
EK+ +E + Q+ + L
Sbjct: 1644 LAQRGEKLSQEAEKLAQKRKKL 1665
Score = 28.5 bits (62), Expect = 3.4
Identities = 15/55 (27%), Positives = 32/55 (58%)
Query: 118 VEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVE 172
VEE+ +E+E ++++EK E E+ + E K++++ +EK +E+ V+
Sbjct: 1891 VEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQ 1945
Score = 27.7 bits (60), Expect = 5.9
Identities = 17/57 (29%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEE-DEEEEEKEGKKMEEEKVEEE 174
++EE + ++ ++ K +KE + ++E KEE D EE +E +EE+ V++E
Sbjct: 1389 KKEEKKTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQE 1445
Score = 27.7 bits (60), Expect = 5.9
Identities = 23/70 (32%), Positives = 35/70 (50%), Gaps = 15/70 (21%)
Query: 124 EEEEEEVEEEEKEE---EKEEDEEEEEKEEEKEEDEE------------EEEKEGKKMEE 168
E E+ ++EEEK EK EEE +E++K + EE +E++ K EE
Sbjct: 1484 EWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEE 1543
Query: 169 EKVEEEIDTE 178
+EEE+ E
Sbjct: 1544 VTLEEEVSRE 1553
Score = 27.7 bits (60), Expect = 5.9
Identities = 22/79 (27%), Positives = 38/79 (48%), Gaps = 12/79 (15%)
Query: 108 EECSAQQGLPVEEEE----------VEEEEEEVEEEEKEEEKEED--EEEEEKEEEKEED 155
EE AQ+ + +EE +++ E + E K +KEE + E+ +E E+
Sbjct: 1599 EEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKL 1658
Query: 156 EEEEEKEGKKMEEEKVEEE 174
++ +K KK E+ EEE
Sbjct: 1659 AQKRKKLAKKWEKVAREEE 1677
Score = 27.7 bits (60), Expect = 5.9
Identities = 21/66 (31%), Positives = 37/66 (56%), Gaps = 7/66 (10%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKME 167
EE AQ+G E++ +E E++ ++ K+ K+ E+ +EEEK + + E K +
Sbjct: 1641 EETLAQRG-----EKLSQEAEKLAQKRKKLAKKW--EKVAREEEKLAKKGGKLAEVKNIL 1693
Query: 168 EEKVEE 173
+KVEE
Sbjct: 1694 AQKVEE 1699
Score = 27.3 bits (59), Expect = 7.7
Identities = 29/124 (23%), Positives = 55/124 (44%), Gaps = 5/124 (4%)
Query: 60 EVEEKWLQRWAVGLPVKDS-GVSQAKIWGKNDLSAGNRLSVARTAALVAEECSAQQGLPV 118
+VEEK Q + K+ ++ K+ D A + +A+ +A E + QG
Sbjct: 1890 QVEEKLTQEKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKR 1949
Query: 119 EEEEVEEEEEE----VEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEE 174
E++ +EE +E + EEK E +E + E E +++ ++E+E E +
Sbjct: 1950 LRGELDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERK 2009
Query: 175 IDTE 178
+ E
Sbjct: 2010 LSLE 2013
Score = 27.3 bits (59), Expect = 7.7
Identities = 16/76 (21%), Positives = 40/76 (52%), Gaps = 3/76 (3%)
Query: 113 QQGLPVEEEEVEEEEEEVEEEEKE---EEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEE 169
Q L ++E + E+ E+ ++EK+ ++++ + ++E+ EEE K +K E
Sbjct: 2115 QSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEV 2174
Query: 170 KVEEEIDTEIQRTQYL 185
+++E + I+ + +
Sbjct: 2175 ILDDEEEGGIEEEEVI 2190
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 66.2 bits (160), Expect = 1e-11
Identities = 40/100 (40%), Positives = 58/100 (58%), Gaps = 1/100 (1%)
Query: 80 VSQAKIWGKNDLSAGNRLSVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEK 139
V + K+ ++ LS +S + AE SA+ G EEEE EEEEEE E EE +
Sbjct: 240 VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE 299
Query: 140 EEDEEEEEKEEEK-EEDEEEEEKEGKKMEEEKVEEEIDTE 178
EE+EEEEE+EEE EE E+ +++ EE++ E+ + E
Sbjct: 300 EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 339
Score = 54.7 bits (130), Expect = 4e-08
Identities = 35/92 (38%), Positives = 46/92 (50%), Gaps = 30/92 (32%)
Query: 117 PVEEEEVEEEE----------------------------EEVEEEEKEEEKEEDEEEEEK 148
PV+EE++EE + E EEEE+EEE+EE EE
Sbjct: 239 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 298
Query: 149 EEEKEEDEEEEEKEGKKMEE--EKVEEEIDTE 178
EEE+EE+EEEEE+ G EE E+ EE+ E
Sbjct: 299 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEE 330
Score = 44.3 bits (103), Expect = 6e-05
Identities = 29/68 (42%), Positives = 33/68 (48%), Gaps = 12/68 (17%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEK-----------EGKKME 167
EEEE EEEEEE E EE E EE EEE EDEE E + + E
Sbjct: 300 EEEEEEEEEEE-ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 358
Query: 168 EEKVEEEI 175
E+ EEE+
Sbjct: 359 SEEAEEEV 366
Score = 38.1 bits (87), Expect = 0.004
Identities = 18/76 (23%), Positives = 36/76 (47%)
Query: 109 ECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEE 168
E Q+ + E E + +E+ E++ E+E E++KE+ ++++ E +E +K E
Sbjct: 135 EWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKERE 194
Query: 169 EKVEEEIDTEIQRTQY 184
+ E R Y
Sbjct: 195 ARREVSAHHRTMREDY 210
Score = 32.0 bits (71), Expect = 0.31
Identities = 19/53 (35%), Positives = 26/53 (49%), Gaps = 6/53 (11%)
Query: 107 AEECSAQQGLPVEEEEVEEEEEEVEEE------EKEEEKEEDEEEEEKEEEKE 153
+EE S Q V EEE+ E+EE E E +++ E EE +EE E
Sbjct: 316 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 368
Score = 29.6 bits (65), Expect = 1.5
Identities = 14/59 (23%), Positives = 31/59 (52%)
Query: 125 EEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQ 183
+E+ ++EK +EK + +E+E E+ + EE+ + ++ E + E+ E R +
Sbjct: 94 KEKVHHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 152
Score = 28.1 bits (61), Expect = 4.5
Identities = 16/57 (28%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Query: 117 PVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEE 173
P + E+ +E+ KE+ K +E E E K EE++K ++ E +K E
Sbjct: 88 PQQMSRKEKVHHRKDEKRKEKWKHARVKEREHERRKRH-REEQDKARREWERQKRRE 143
Score = 28.1 bits (61), Expect = 4.5
Identities = 19/72 (26%), Positives = 36/72 (50%), Gaps = 5/72 (6%)
Query: 106 VAEECSAQQGLPVEE-EEVEEEEEEVEEEEKE----EEKEEDEEEEEKEEEKEEDEEEEE 160
+A E S ++ +E+ E E E ++ E++KE +E+E EE KE E +
Sbjct: 144 MAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHH 203
Query: 161 KEGKKMEEEKVE 172
+ ++ +KV+
Sbjct: 204 RTMREDYSDKVK 215
Score = 27.7 bits (60), Expect = 5.9
Identities = 12/53 (22%), Positives = 28/53 (52%)
Query: 124 EEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEID 176
+E+ +E + + +E+E + + +EE+ + E E ++ ++M E E D
Sbjct: 102 DEKRKEKWKHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERD 154
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 66.2 bits (160), Expect = 1e-11
Identities = 40/100 (40%), Positives = 58/100 (58%), Gaps = 1/100 (1%)
Query: 80 VSQAKIWGKNDLSAGNRLSVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEK 139
V + K+ ++ LS +S + AE SA+ G EEEE EEEEEE E EE +
Sbjct: 250 VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE 309
Query: 140 EEDEEEEEKEEEK-EEDEEEEEKEGKKMEEEKVEEEIDTE 178
EE+EEEEE+EEE EE E+ +++ EE++ E+ + E
Sbjct: 310 EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 349
Score = 54.7 bits (130), Expect = 4e-08
Identities = 35/92 (38%), Positives = 46/92 (50%), Gaps = 30/92 (32%)
Query: 117 PVEEEEVEEEE----------------------------EEVEEEEKEEEKEEDEEEEEK 148
PV+EE++EE + E EEEE+EEE+EE EE
Sbjct: 249 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 308
Query: 149 EEEKEEDEEEEEKEGKKMEE--EKVEEEIDTE 178
EEE+EE+EEEEE+ G EE E+ EE+ E
Sbjct: 309 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEE 340
Score = 44.3 bits (103), Expect = 6e-05
Identities = 29/68 (42%), Positives = 33/68 (48%), Gaps = 12/68 (17%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEK-----------EGKKME 167
EEEE EEEEEE E EE E EE EEE EDEE E + + E
Sbjct: 310 EEEEEEEEEEE-ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 368
Query: 168 EEKVEEEI 175
E+ EEE+
Sbjct: 369 SEEAEEEV 376
Score = 38.1 bits (87), Expect = 0.004
Identities = 18/76 (23%), Positives = 36/76 (47%)
Query: 109 ECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEE 168
E Q+ + E E + +E+ E++ E+E E++KE+ ++++ E +E +K E
Sbjct: 145 EWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKERE 204
Query: 169 EKVEEEIDTEIQRTQY 184
+ E R Y
Sbjct: 205 ARREVSAHHRTMREDY 220
Score = 32.0 bits (71), Expect = 0.31
Identities = 19/53 (35%), Positives = 26/53 (49%), Gaps = 6/53 (11%)
Query: 107 AEECSAQQGLPVEEEEVEEEEEEVEEE------EKEEEKEEDEEEEEKEEEKE 153
+EE S Q V EEE+ E+EE E E +++ E EE +EE E
Sbjct: 326 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGE 378
Score = 28.1 bits (61), Expect = 4.5
Identities = 19/72 (26%), Positives = 36/72 (50%), Gaps = 5/72 (6%)
Query: 106 VAEECSAQQGLPVEE-EEVEEEEEEVEEEEKE----EEKEEDEEEEEKEEEKEEDEEEEE 160
+A E S ++ +E+ E E E ++ E++KE +E+E EE KE E +
Sbjct: 154 MAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHH 213
Query: 161 KEGKKMEEEKVE 172
+ ++ +KV+
Sbjct: 214 RTMREDYSDKVK 225
>gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo
sapiens]
Length = 5033
Score = 66.2 bits (160), Expect = 1e-11
Identities = 36/54 (66%), Positives = 41/54 (75%), Gaps = 2/54 (3%)
Query: 120 EEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEE 173
EEE EE+EEE EEE EEEKEEDEEE +E+E EE EEEE EG+K EE +EE
Sbjct: 1873 EEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEK--EEGLEE 1924
Score = 59.7 bits (143), Expect = 1e-09
Identities = 30/64 (46%), Positives = 47/64 (73%)
Query: 113 QQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVE 172
+Q L + E EV EEEE E+EE+E E+E++EE+EE EEE +++E+EEKE ++ E + E
Sbjct: 1860 KQILKMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKE 1919
Query: 173 EEID 176
E ++
Sbjct: 1920 EGLE 1923
Score = 54.7 bits (130), Expect = 4e-08
Identities = 29/67 (43%), Positives = 48/67 (71%), Gaps = 1/67 (1%)
Query: 120 EEEVEEEEEEVEEEE-KEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
+E+V++ + +E E EEE+EEDEEEE +EE++EE EE+EE+ ++ E+E+ EEE E
Sbjct: 1856 DEDVKQILKMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAE 1915
Query: 179 IQRTQYL 185
++ + L
Sbjct: 1916 GEKEEGL 1922
Score = 49.7 bits (117), Expect = 1e-06
Identities = 30/65 (46%), Positives = 40/65 (61%), Gaps = 3/65 (4%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKME 167
EE ++G EEE+ EE+EE+ EE +E+E EE EEEE E EKEE EE + K E
Sbjct: 1877 EEDEEEEG---EEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEEGLLQMKLPE 1933
Query: 168 EEKVE 172
K++
Sbjct: 1934 SVKLQ 1938
Score = 35.0 bits (79), Expect = 0.037
Identities = 27/76 (35%), Positives = 35/76 (46%), Gaps = 6/76 (7%)
Query: 115 GLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEE 174
G+ EEE+ E E E E E EK D E EKEE E E +K+ K EE
Sbjct: 4474 GVDGVEEELPPEPEPEPEPELEPEKA-DAENGEKEEVPEPTPEPPKKQAPPSPPPKKEEA 4532
Query: 175 I-----DTEIQRTQYL 185
+ E+QR ++L
Sbjct: 4533 GGEFWGELEVQRVKFL 4548
Score = 28.9 bits (63), Expect = 2.6
Identities = 15/60 (25%), Positives = 33/60 (55%)
Query: 122 EVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQR 181
+++ EEEE EEE + E+ + +K+E++ EEE+ ++ + ++E + + R
Sbjct: 2045 QLDGEEEEPEEETTLGSRLMSLLEKVRLVKKKEEKPEEERSAEESKPRSLQELVSHMVVR 2104
>gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo
sapiens]
Length = 5038
Score = 66.2 bits (160), Expect = 1e-11
Identities = 36/54 (66%), Positives = 41/54 (75%), Gaps = 2/54 (3%)
Query: 120 EEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEE 173
EEE EE+EEE EEE EEEKEEDEEE +E+E EE EEEE EG+K EE +EE
Sbjct: 1873 EEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEK--EEGLEE 1924
Score = 59.7 bits (143), Expect = 1e-09
Identities = 30/64 (46%), Positives = 47/64 (73%)
Query: 113 QQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVE 172
+Q L + E EV EEEE E+EE+E E+E++EE+EE EEE +++E+EEKE ++ E + E
Sbjct: 1860 KQILKMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKE 1919
Query: 173 EEID 176
E ++
Sbjct: 1920 EGLE 1923
Score = 54.7 bits (130), Expect = 4e-08
Identities = 29/67 (43%), Positives = 48/67 (71%), Gaps = 1/67 (1%)
Query: 120 EEEVEEEEEEVEEEE-KEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
+E+V++ + +E E EEE+EEDEEEE +EE++EE EE+EE+ ++ E+E+ EEE E
Sbjct: 1856 DEDVKQILKMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAE 1915
Query: 179 IQRTQYL 185
++ + L
Sbjct: 1916 GEKEEGL 1922
Score = 49.7 bits (117), Expect = 1e-06
Identities = 30/65 (46%), Positives = 40/65 (61%), Gaps = 3/65 (4%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKME 167
EE ++G EEE+ EE+EE+ EE +E+E EE EEEE E EKEE EE + K E
Sbjct: 1877 EEDEEEEG---EEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEEGLLQMKLPE 1933
Query: 168 EEKVE 172
K++
Sbjct: 1934 SVKLQ 1938
Score = 35.0 bits (79), Expect = 0.037
Identities = 27/76 (35%), Positives = 35/76 (46%), Gaps = 6/76 (7%)
Query: 115 GLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEE 174
G+ EEE+ E E E E E EK D E EKEE E E +K+ K EE
Sbjct: 4479 GVDGVEEELPPEPEPEPEPELEPEKA-DAENGEKEEVPEPTPEPPKKQAPPSPPPKKEEA 4537
Query: 175 I-----DTEIQRTQYL 185
+ E+QR ++L
Sbjct: 4538 GGEFWGELEVQRVKFL 4553
Score = 28.9 bits (63), Expect = 2.6
Identities = 15/60 (25%), Positives = 33/60 (55%)
Query: 122 EVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQR 181
+++ EEEE EEE + E+ + +K+E++ EEE+ ++ + ++E + + R
Sbjct: 2045 QLDGEEEEPEEETTLGSRLMSLLEKVRLVKKKEEKPEEERSAEESKPRSLQELVSHMVVR 2104
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 66.2 bits (160), Expect = 1e-11
Identities = 40/100 (40%), Positives = 58/100 (58%), Gaps = 1/100 (1%)
Query: 80 VSQAKIWGKNDLSAGNRLSVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEK 139
V + K+ ++ LS +S + AE SA+ G EEEE EEEEEE E EE +
Sbjct: 241 VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE 300
Query: 140 EEDEEEEEKEEEK-EEDEEEEEKEGKKMEEEKVEEEIDTE 178
EE+EEEEE+EEE EE E+ +++ EE++ E+ + E
Sbjct: 301 EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 340
Score = 54.7 bits (130), Expect = 4e-08
Identities = 35/92 (38%), Positives = 46/92 (50%), Gaps = 30/92 (32%)
Query: 117 PVEEEEVEEEE----------------------------EEVEEEEKEEEKEEDEEEEEK 148
PV+EE++EE + E EEEE+EEE+EE EE
Sbjct: 240 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 299
Query: 149 EEEKEEDEEEEEKEGKKMEE--EKVEEEIDTE 178
EEE+EE+EEEEE+ G EE E+ EE+ E
Sbjct: 300 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEE 331
Score = 44.3 bits (103), Expect = 6e-05
Identities = 29/68 (42%), Positives = 33/68 (48%), Gaps = 12/68 (17%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEK-----------EGKKME 167
EEEE EEEEEE E EE E EE EEE EDEE E + + E
Sbjct: 301 EEEEEEEEEEE-ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 359
Query: 168 EEKVEEEI 175
E+ EEE+
Sbjct: 360 SEEAEEEV 367
Score = 38.1 bits (87), Expect = 0.004
Identities = 18/76 (23%), Positives = 36/76 (47%)
Query: 109 ECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEE 168
E Q+ + E E + +E+ E++ E+E E++KE+ ++++ E +E +K E
Sbjct: 136 EWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKERE 195
Query: 169 EKVEEEIDTEIQRTQY 184
+ E R Y
Sbjct: 196 ARREVSAHHRTMREDY 211
Score = 34.3 bits (77), Expect = 0.063
Identities = 18/61 (29%), Positives = 33/61 (54%), Gaps = 4/61 (6%)
Query: 118 VEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEE----EEKEGKKMEEEKVEE 173
V+E+E E E + EE+++ + E E ++ +E +E E E+ E K+ E K+ E
Sbjct: 113 VKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMRE 172
Query: 174 E 174
+
Sbjct: 173 Q 173
Score = 33.5 bits (75), Expect = 0.11
Identities = 15/67 (22%), Positives = 37/67 (55%)
Query: 117 PVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEID 176
P ++ +E+ ++E+++E+K +E+E+E E+ + EE+ + ++ E + E+
Sbjct: 87 PPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMA 146
Query: 177 TEIQRTQ 183
E R +
Sbjct: 147 REHSRRE 153
Score = 33.1 bits (74), Expect = 0.14
Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 7/86 (8%)
Query: 107 AEECSAQQGLPVEEEEVEEEEEEVEEE------EKEEEKEEDEEEEEKEEEKEEDEEEEE 160
+EE S Q V EEE+ E+EE E E +++ E EE +EE E +
Sbjct: 317 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSA 376
Query: 161 -KEGKKMEEEKVEEEIDTEIQRTQYL 185
EG + + I+ + + +YL
Sbjct: 377 LTEGDYVPDSPALSPIELKQELPKYL 402
Score = 32.0 bits (71), Expect = 0.31
Identities = 15/59 (25%), Positives = 30/59 (50%)
Query: 118 VEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEID 176
V + E+ +E+ KE+E+E + + +EE+ + E E ++ ++M E E D
Sbjct: 97 VHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERD 155
Score = 31.2 bits (69), Expect = 0.53
Identities = 14/74 (18%), Positives = 37/74 (50%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKME 167
E+ +G + ++ ++ +E+ K+E +E++ KE++ E E ++ + E
Sbjct: 70 EDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREE 129
Query: 168 EEKVEEEIDTEIQR 181
++K E + + +R
Sbjct: 130 QDKARREWERQKRR 143
Score = 31.2 bits (69), Expect = 0.53
Identities = 16/67 (23%), Positives = 33/67 (49%), Gaps = 1/67 (1%)
Query: 120 EEEVEEEEEEVEEEEKEEE-KEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
+E+V ++E +E+K KE++ E E ++ +EE ++ + ++ E E E
Sbjct: 94 KEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 153
Query: 179 IQRTQYL 185
R + L
Sbjct: 154 RDRLEQL 160
Score = 31.2 bits (69), Expect = 0.53
Identities = 16/73 (21%), Positives = 40/73 (54%), Gaps = 8/73 (10%)
Query: 119 EEEEVEEEEEEVEEEEKE--------EEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEK 170
+E+ E++ V+E+E+E EE+++ E E+++ +E E +E ++E+ +
Sbjct: 102 DEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLE 161
Query: 171 VEEEIDTEIQRTQ 183
+ E + +++ Q
Sbjct: 162 RKRERERKMREQQ 174
Score = 28.1 bits (61), Expect = 4.5
Identities = 19/72 (26%), Positives = 36/72 (50%), Gaps = 5/72 (6%)
Query: 106 VAEECSAQQGLPVEE-EEVEEEEEEVEEEEKE----EEKEEDEEEEEKEEEKEEDEEEEE 160
+A E S ++ +E+ E E E ++ E++KE +E+E EE KE E +
Sbjct: 145 MAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHH 204
Query: 161 KEGKKMEEEKVE 172
+ ++ +KV+
Sbjct: 205 RTMREDYSDKVK 216
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 66.2 bits (160), Expect = 1e-11
Identities = 40/100 (40%), Positives = 58/100 (58%), Gaps = 1/100 (1%)
Query: 80 VSQAKIWGKNDLSAGNRLSVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEK 139
V + K+ ++ LS +S + AE SA+ G EEEE EEEEEE E EE +
Sbjct: 250 VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE 309
Query: 140 EEDEEEEEKEEEK-EEDEEEEEKEGKKMEEEKVEEEIDTE 178
EE+EEEEE+EEE EE E+ +++ EE++ E+ + E
Sbjct: 310 EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 349
Score = 54.7 bits (130), Expect = 4e-08
Identities = 35/92 (38%), Positives = 46/92 (50%), Gaps = 30/92 (32%)
Query: 117 PVEEEEVEEEE----------------------------EEVEEEEKEEEKEEDEEEEEK 148
PV+EE++EE + E EEEE+EEE+EE EE
Sbjct: 249 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 308
Query: 149 EEEKEEDEEEEEKEGKKMEE--EKVEEEIDTE 178
EEE+EE+EEEEE+ G EE E+ EE+ E
Sbjct: 309 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEE 340
Score = 44.3 bits (103), Expect = 6e-05
Identities = 29/68 (42%), Positives = 33/68 (48%), Gaps = 12/68 (17%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEK-----------EGKKME 167
EEEE EEEEEE E EE E EE EEE EDEE E + + E
Sbjct: 310 EEEEEEEEEEE-ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 368
Query: 168 EEKVEEEI 175
E+ EEE+
Sbjct: 369 SEEAEEEV 376
Score = 33.9 bits (76), Expect = 0.082
Identities = 14/57 (24%), Positives = 30/57 (52%)
Query: 128 EEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQY 184
+ +E+ E++ E+E E++KE+ ++++ E +E +K E + E R Y
Sbjct: 164 DRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDY 220
Score = 33.9 bits (76), Expect = 0.082
Identities = 12/41 (29%), Positives = 26/41 (63%)
Query: 125 EEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKK 165
E+ E E E++ +++ E+ E+KE E+ +E +E+E ++
Sbjct: 167 EQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR 207
Score = 33.5 bits (75), Expect = 0.11
Identities = 15/67 (22%), Positives = 37/67 (55%)
Query: 117 PVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEID 176
P ++ +E+ ++E+++E+K +E+E+E E+ + EE+ + ++ E + E+
Sbjct: 87 PPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMA 146
Query: 177 TEIQRTQ 183
E R +
Sbjct: 147 REHSRRE 153
Score = 33.1 bits (74), Expect = 0.14
Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 7/86 (8%)
Query: 107 AEECSAQQGLPVEEEEVEEEEEEVEEE------EKEEEKEEDEEEEEKEEEKEEDEEEEE 160
+EE S Q V EEE+ E+EE E E +++ E EE +EE E +
Sbjct: 326 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSA 385
Query: 161 -KEGKKMEEEKVEEEIDTEIQRTQYL 185
EG + + I+ + + +YL
Sbjct: 386 LTEGDYVPDSPALSPIELKQELPKYL 411
Score = 32.7 bits (73), Expect = 0.18
Identities = 14/56 (25%), Positives = 31/56 (55%)
Query: 118 VEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEE 173
V+E+E E E + EE+++ + E E ++ +E +E E +G + +++E+
Sbjct: 113 VKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQ 168
Score = 31.2 bits (69), Expect = 0.53
Identities = 14/74 (18%), Positives = 37/74 (50%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKME 167
E+ +G + ++ ++ +E+ K+E +E++ KE++ E E ++ + E
Sbjct: 70 EDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREE 129
Query: 168 EEKVEEEIDTEIQR 181
++K E + + +R
Sbjct: 130 QDKARREWERQKRR 143
Score = 30.0 bits (66), Expect = 1.2
Identities = 14/39 (35%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
Query: 121 EEVEEEEEEVEEEEKE--EEKEEDEEEEEKEEEKEEDEE 157
E E E ++ E++KE E+KE + EE+ +E+E E
Sbjct: 170 ERKRERERKMREQQKEQREQKERERRAEERRKEREARRE 208
Score = 29.6 bits (65), Expect = 1.5
Identities = 12/42 (28%), Positives = 24/42 (57%)
Query: 127 EEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEE 168
E+ + E+E + E ++E+ +++E+E EE KE + E
Sbjct: 167 EQLERKRERERKMREQQKEQREQKERERRAEERRKEREARRE 208
Score = 29.6 bits (65), Expect = 1.5
Identities = 11/35 (31%), Positives = 21/35 (60%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKE 153
E E E+++ + E+KE E+ +E +E+E +E
Sbjct: 174 ERERKMREQQKEQREQKERERRAEERRKEREARRE 208
Score = 27.3 bits (59), Expect = 7.7
Identities = 13/53 (24%), Positives = 29/53 (54%), Gaps = 1/53 (1%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEE-DEEEEEKEEEKEEDEEEEEKEGKKMEEEK 170
+E+ E++ V+E+E+E E+ + EE++K + E ++ E + E+
Sbjct: 102 DEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRER 154
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 66.2 bits (160), Expect = 1e-11
Identities = 40/100 (40%), Positives = 58/100 (58%), Gaps = 1/100 (1%)
Query: 80 VSQAKIWGKNDLSAGNRLSVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEK 139
V + K+ ++ LS +S + AE SA+ G EEEE EEEEEE E EE +
Sbjct: 218 VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE 277
Query: 140 EEDEEEEEKEEEK-EEDEEEEEKEGKKMEEEKVEEEIDTE 178
EE+EEEEE+EEE EE E+ +++ EE++ E+ + E
Sbjct: 278 EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 317
Score = 54.7 bits (130), Expect = 4e-08
Identities = 35/92 (38%), Positives = 46/92 (50%), Gaps = 30/92 (32%)
Query: 117 PVEEEEVEEEE----------------------------EEVEEEEKEEEKEEDEEEEEK 148
PV+EE++EE + E EEEE+EEE+EE EE
Sbjct: 217 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 276
Query: 149 EEEKEEDEEEEEKEGKKMEE--EKVEEEIDTE 178
EEE+EE+EEEEE+ G EE E+ EE+ E
Sbjct: 277 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEE 308
Score = 44.3 bits (103), Expect = 6e-05
Identities = 29/68 (42%), Positives = 33/68 (48%), Gaps = 12/68 (17%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEK-----------EGKKME 167
EEEE EEEEEE E EE E EE EEE EDEE E + + E
Sbjct: 278 EEEEEEEEEEE-ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 336
Query: 168 EEKVEEEI 175
E+ EEE+
Sbjct: 337 SEEAEEEV 344
Score = 38.1 bits (87), Expect = 0.004
Identities = 18/76 (23%), Positives = 36/76 (47%)
Query: 109 ECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEE 168
E Q+ + E E + +E+ E++ E+E E++KE+ ++++ E +E +K E
Sbjct: 113 EWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKERE 172
Query: 169 EKVEEEIDTEIQRTQY 184
+ E R Y
Sbjct: 173 ARREVSAHHRTMREDY 188
Score = 34.3 bits (77), Expect = 0.063
Identities = 18/61 (29%), Positives = 33/61 (54%), Gaps = 4/61 (6%)
Query: 118 VEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEE----EEKEGKKMEEEKVEE 173
V+E+E E E + EE+++ + E E ++ +E +E E E+ E K+ E K+ E
Sbjct: 90 VKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMRE 149
Query: 174 E 174
+
Sbjct: 150 Q 150
Score = 33.1 bits (74), Expect = 0.14
Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 7/86 (8%)
Query: 107 AEECSAQQGLPVEEEEVEEEEEEVEEE------EKEEEKEEDEEEEEKEEEKEEDEEEEE 160
+EE S Q V EEE+ E+EE E E +++ E EE +EE E +
Sbjct: 294 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSA 353
Query: 161 -KEGKKMEEEKVEEEIDTEIQRTQYL 185
EG + + I+ + + +YL
Sbjct: 354 LTEGDYVPDSPALSPIELKQELPKYL 379
Score = 30.4 bits (67), Expect = 0.91
Identities = 13/60 (21%), Positives = 32/60 (53%)
Query: 124 EEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQ 183
E+E E + EE+++ E E+++ +E E +E ++E+ + + E + +++ Q
Sbjct: 92 EKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQ 151
Score = 29.3 bits (64), Expect = 2.0
Identities = 15/76 (19%), Positives = 36/76 (47%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKME 167
++ S ++ + ++E +E+ E K +E+E+E E+ + EE+ + ++
Sbjct: 55 QQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREW 114
Query: 168 EEKVEEEIDTEIQRTQ 183
E + E+ E R +
Sbjct: 115 ERQKRREMAREHSRRE 130
Score = 28.9 bits (63), Expect = 2.6
Identities = 13/54 (24%), Positives = 26/54 (48%)
Query: 125 EEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
+E+E E K +E+D+ E E +K + E ++ E++E + + E
Sbjct: 91 KEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERE 144
Score = 28.1 bits (61), Expect = 4.5
Identities = 19/72 (26%), Positives = 36/72 (50%), Gaps = 5/72 (6%)
Query: 106 VAEECSAQQGLPVEE-EEVEEEEEEVEEEEKE----EEKEEDEEEEEKEEEKEEDEEEEE 160
+A E S ++ +E+ E E E ++ E++KE +E+E EE KE E +
Sbjct: 122 MAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHH 181
Query: 161 KEGKKMEEEKVE 172
+ ++ +KV+
Sbjct: 182 RTMREDYSDKVK 193
Score = 27.3 bits (59), Expect = 7.7
Identities = 14/67 (20%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Query: 117 PVEEEEVEEEEEEVEEEEKEEEKEEDEEEE--EKEEEKEEDEEEEEKEGKKMEEEKVEEE 174
P + E+ +E+ KE+ + E + KE++ E E ++ + E++K E
Sbjct: 54 PQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARRE 113
Query: 175 IDTEIQR 181
+ + +R
Sbjct: 114 WERQKRR 120
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 66.2 bits (160), Expect = 1e-11
Identities = 40/100 (40%), Positives = 58/100 (58%), Gaps = 1/100 (1%)
Query: 80 VSQAKIWGKNDLSAGNRLSVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEK 139
V + K+ ++ LS +S + AE SA+ G EEEE EEEEEE E EE +
Sbjct: 207 VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE 266
Query: 140 EEDEEEEEKEEEK-EEDEEEEEKEGKKMEEEKVEEEIDTE 178
EE+EEEEE+EEE EE E+ +++ EE++ E+ + E
Sbjct: 267 EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 306
Score = 54.7 bits (130), Expect = 4e-08
Identities = 35/92 (38%), Positives = 46/92 (50%), Gaps = 30/92 (32%)
Query: 117 PVEEEEVEEEE----------------------------EEVEEEEKEEEKEEDEEEEEK 148
PV+EE++EE + E EEEE+EEE+EE EE
Sbjct: 206 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 265
Query: 149 EEEKEEDEEEEEKEGKKMEE--EKVEEEIDTE 178
EEE+EE+EEEEE+ G EE E+ EE+ E
Sbjct: 266 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEE 297
Score = 44.3 bits (103), Expect = 6e-05
Identities = 29/68 (42%), Positives = 33/68 (48%), Gaps = 12/68 (17%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEK-----------EGKKME 167
EEEE EEEEEE E EE E EE EEE EDEE E + + E
Sbjct: 267 EEEEEEEEEEE-ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 325
Query: 168 EEKVEEEI 175
E+ EEE+
Sbjct: 326 SEEAEEEV 333
Score = 38.1 bits (87), Expect = 0.004
Identities = 18/76 (23%), Positives = 36/76 (47%)
Query: 109 ECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEE 168
E Q+ + E E + +E+ E++ E+E E++KE+ ++++ E +E +K E
Sbjct: 102 EWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKERE 161
Query: 169 EKVEEEIDTEIQRTQY 184
+ E R Y
Sbjct: 162 ARREVSAHHRTMREDY 177
Score = 34.3 bits (77), Expect = 0.063
Identities = 18/61 (29%), Positives = 33/61 (54%), Gaps = 4/61 (6%)
Query: 118 VEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEE----EEKEGKKMEEEKVEE 173
V+E+E E E + EE+++ + E E ++ +E +E E E+ E K+ E K+ E
Sbjct: 79 VKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMRE 138
Query: 174 E 174
+
Sbjct: 139 Q 139
Score = 33.5 bits (75), Expect = 0.11
Identities = 15/67 (22%), Positives = 37/67 (55%)
Query: 117 PVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEID 176
P ++ +E+ ++E+++E+K +E+E+E E+ + EE+ + ++ E + E+
Sbjct: 53 PPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMA 112
Query: 177 TEIQRTQ 183
E R +
Sbjct: 113 REHSRRE 119
Score = 33.1 bits (74), Expect = 0.14
Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 7/86 (8%)
Query: 107 AEECSAQQGLPVEEEEVEEEEEEVEEE------EKEEEKEEDEEEEEKEEEKEEDEEEEE 160
+EE S Q V EEE+ E+EE E E +++ E EE +EE E +
Sbjct: 283 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSA 342
Query: 161 -KEGKKMEEEKVEEEIDTEIQRTQYL 185
EG + + I+ + + +YL
Sbjct: 343 LTEGDYVPDSPALSPIELKQELPKYL 368
Score = 32.0 bits (71), Expect = 0.31
Identities = 15/59 (25%), Positives = 30/59 (50%)
Query: 118 VEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEID 176
V + E+ +E+ KE+E+E + + +EE+ + E E ++ ++M E E D
Sbjct: 63 VHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERD 121
Score = 31.2 bits (69), Expect = 0.53
Identities = 14/74 (18%), Positives = 37/74 (50%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKME 167
E+ +G + ++ ++ +E+ K+E +E++ KE++ E E ++ + E
Sbjct: 36 EDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREE 95
Query: 168 EEKVEEEIDTEIQR 181
++K E + + +R
Sbjct: 96 QDKARREWERQKRR 109
Score = 31.2 bits (69), Expect = 0.53
Identities = 16/67 (23%), Positives = 33/67 (49%), Gaps = 1/67 (1%)
Query: 120 EEEVEEEEEEVEEEEKEEE-KEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
+E+V ++E +E+K KE++ E E ++ +EE ++ + ++ E E E
Sbjct: 60 KEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRE 119
Query: 179 IQRTQYL 185
R + L
Sbjct: 120 RDRLEQL 126
Score = 31.2 bits (69), Expect = 0.53
Identities = 16/73 (21%), Positives = 40/73 (54%), Gaps = 8/73 (10%)
Query: 119 EEEEVEEEEEEVEEEEKE--------EEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEK 170
+E+ E++ V+E+E+E EE+++ E E+++ +E E +E ++E+ +
Sbjct: 68 DEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLE 127
Query: 171 VEEEIDTEIQRTQ 183
+ E + +++ Q
Sbjct: 128 RKRERERKMREQQ 140
Score = 28.1 bits (61), Expect = 4.5
Identities = 19/72 (26%), Positives = 36/72 (50%), Gaps = 5/72 (6%)
Query: 106 VAEECSAQQGLPVEE-EEVEEEEEEVEEEEKE----EEKEEDEEEEEKEEEKEEDEEEEE 160
+A E S ++ +E+ E E E ++ E++KE +E+E EE KE E +
Sbjct: 111 MAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHH 170
Query: 161 KEGKKMEEEKVE 172
+ ++ +KV+
Sbjct: 171 RTMREDYSDKVK 182
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 66.2 bits (160), Expect = 1e-11
Identities = 40/100 (40%), Positives = 58/100 (58%), Gaps = 1/100 (1%)
Query: 80 VSQAKIWGKNDLSAGNRLSVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEK 139
V + K+ ++ LS +S + AE SA+ G EEEE EEEEEE E EE +
Sbjct: 252 VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE 311
Query: 140 EEDEEEEEKEEEK-EEDEEEEEKEGKKMEEEKVEEEIDTE 178
EE+EEEEE+EEE EE E+ +++ EE++ E+ + E
Sbjct: 312 EEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 351
Score = 54.7 bits (130), Expect = 4e-08
Identities = 35/92 (38%), Positives = 46/92 (50%), Gaps = 30/92 (32%)
Query: 117 PVEEEEVEEEE----------------------------EEVEEEEKEEEKEEDEEEEEK 148
PV+EE++EE + E EEEE+EEE+EE EE
Sbjct: 251 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES 310
Query: 149 EEEKEEDEEEEEKEGKKMEE--EKVEEEIDTE 178
EEE+EE+EEEEE+ G EE E+ EE+ E
Sbjct: 311 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEE 342
Score = 44.3 bits (103), Expect = 6e-05
Identities = 29/68 (42%), Positives = 33/68 (48%), Gaps = 12/68 (17%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEK-----------EGKKME 167
EEEE EEEEEE E EE E EE EEE EDEE E + + E
Sbjct: 312 EEEEEEEEEEE-ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 370
Query: 168 EEKVEEEI 175
E+ EEE+
Sbjct: 371 SEEAEEEV 378
Score = 38.1 bits (87), Expect = 0.004
Identities = 18/76 (23%), Positives = 36/76 (47%)
Query: 109 ECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEE 168
E Q+ + E E + +E+ E++ E+E E++KE+ ++++ E +E +K E
Sbjct: 147 EWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKERE 206
Query: 169 EKVEEEIDTEIQRTQY 184
+ E R Y
Sbjct: 207 ARREVSAHHRTMREDY 222
Score = 34.3 bits (77), Expect = 0.063
Identities = 18/61 (29%), Positives = 33/61 (54%), Gaps = 4/61 (6%)
Query: 118 VEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEE----EEKEGKKMEEEKVEE 173
V+E+E E E + EE+++ + E E ++ +E +E E E+ E K+ E K+ E
Sbjct: 124 VKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMRE 183
Query: 174 E 174
+
Sbjct: 184 Q 184
Score = 33.1 bits (74), Expect = 0.14
Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 7/86 (8%)
Query: 107 AEECSAQQGLPVEEEEVEEEEEEVEEE------EKEEEKEEDEEEEEKEEEKEEDEEEEE 160
+EE S Q V EEE+ E+EE E E +++ E EE +EE E +
Sbjct: 328 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSA 387
Query: 161 -KEGKKMEEEKVEEEIDTEIQRTQYL 185
EG + + I+ + + +YL
Sbjct: 388 LTEGDYVPDSPALSPIELKQELPKYL 413
Score = 30.4 bits (67), Expect = 0.91
Identities = 13/60 (21%), Positives = 32/60 (53%)
Query: 124 EEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQ 183
E+E E + EE+++ E E+++ +E E +E ++E+ + + E + +++ Q
Sbjct: 126 EKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQ 185
Score = 29.3 bits (64), Expect = 2.0
Identities = 15/76 (19%), Positives = 36/76 (47%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKME 167
++ S ++ + ++E +E+ E K +E+E+E E+ + EE+ + ++
Sbjct: 89 QQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREW 148
Query: 168 EEKVEEEIDTEIQRTQ 183
E + E+ E R +
Sbjct: 149 ERQKRREMAREHSRRE 164
Score = 28.9 bits (63), Expect = 2.6
Identities = 13/54 (24%), Positives = 26/54 (48%)
Query: 125 EEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
+E+E E K +E+D+ E E +K + E ++ E++E + + E
Sbjct: 125 KEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERE 178
Score = 28.1 bits (61), Expect = 4.5
Identities = 19/72 (26%), Positives = 36/72 (50%), Gaps = 5/72 (6%)
Query: 106 VAEECSAQQGLPVEE-EEVEEEEEEVEEEEKE----EEKEEDEEEEEKEEEKEEDEEEEE 160
+A E S ++ +E+ E E E ++ E++KE +E+E EE KE E +
Sbjct: 156 MAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHH 215
Query: 161 KEGKKMEEEKVE 172
+ ++ +KV+
Sbjct: 216 RTMREDYSDKVK 227
Score = 27.3 bits (59), Expect = 7.7
Identities = 14/67 (20%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Query: 117 PVEEEEVEEEEEEVEEEEKEEEKEEDEEEE--EKEEEKEEDEEEEEKEGKKMEEEKVEEE 174
P + E+ +E+ KE+ + E + KE++ E E ++ + E++K E
Sbjct: 88 PQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARRE 147
Query: 175 IDTEIQR 181
+ + +R
Sbjct: 148 WERQKRR 154
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 66.2 bits (160), Expect = 1e-11
Identities = 35/74 (47%), Positives = 49/74 (66%)
Query: 111 SAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEK 170
S +QG E EE EE+ E+EE EE+ EEDEE +E EE+EE+EEEEE+E ++ EEE
Sbjct: 191 SDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEY 250
Query: 171 VEEEIDTEIQRTQY 184
++E D + + Y
Sbjct: 251 EQDERDQKEEGNDY 264
Score = 64.3 bits (155), Expect = 6e-11
Identities = 30/65 (46%), Positives = 48/65 (73%)
Query: 113 QQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVE 172
++G+ + EE EE EE+ EE+E+ +E E+EEEEE+EEE+EE+EEEEE E + ++++
Sbjct: 202 EEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEG 261
Query: 173 EEIDT 177
+ DT
Sbjct: 262 NDYDT 266
Score = 60.8 bits (146), Expect = 6e-10
Identities = 31/66 (46%), Positives = 45/66 (68%), Gaps = 6/66 (9%)
Query: 119 EEEEVEEEEEEVEE------EEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVE 172
E+EEVEE+ EE EE EE+EEE+EE+EEEEE+EEE E+DE ++++EG +
Sbjct: 211 EDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEA 270
Query: 173 EEIDTE 178
+ +E
Sbjct: 271 SDSGSE 276
Score = 56.2 bits (134), Expect = 2e-08
Identities = 31/73 (42%), Positives = 45/73 (61%)
Query: 111 SAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEK 170
+ G E+ E EEE EE+ EE++E +E+ EE EE E+ EEEEE+E ++ EEE+
Sbjct: 185 TGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEE 244
Query: 171 VEEEIDTEIQRTQ 183
EEE + +R Q
Sbjct: 245 EEEEEYEQDERDQ 257
Score = 53.5 bits (127), Expect = 1e-07
Identities = 25/58 (43%), Positives = 42/58 (72%), Gaps = 1/58 (1%)
Query: 119 EEEEVEEE-EEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEI 175
E+EEV+E+ EEE EEEE+EEE+EE+EEEE +++E+++ EE + + + + E +
Sbjct: 221 EDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESV 278
Score = 52.8 bits (125), Expect = 2e-07
Identities = 25/63 (39%), Positives = 42/63 (66%)
Query: 109 ECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEE 168
E A++ V+E+ EEEEEE EEEE+EEE+EE+ E++E+++++E ++ + E
Sbjct: 216 EEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGS 275
Query: 169 EKV 171
E V
Sbjct: 276 ESV 278
Score = 47.4 bits (111), Expect = 7e-06
Identities = 27/87 (31%), Positives = 53/87 (60%), Gaps = 2/87 (2%)
Query: 100 ARTAALVAEECSAQQ-GLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEE 158
+R++ EE ++++ G E +E+ E EEE E++ EE++E E++ +E+E
Sbjct: 164 SRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDE 223
Query: 159 E-EKEGKKMEEEKVEEEIDTEIQRTQY 184
E +++G++ EEE+ EEE + E + +Y
Sbjct: 224 EVDEDGEEEEEEEEEEEEEEEEEEEEY 250
Score = 45.1 bits (105), Expect = 4e-05
Identities = 23/66 (34%), Positives = 34/66 (51%)
Query: 113 QQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVE 172
+ G EEEE EEEEEE EEEE+ E+ E D++EE + + + + E + V
Sbjct: 227 EDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVR 286
Query: 173 EEIDTE 178
T+
Sbjct: 287 SGSGTD 292
Score = 28.1 bits (61), Expect = 4.5
Identities = 16/66 (24%), Positives = 28/66 (42%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKME 167
EE ++ EEEE E++E + +EE + + + + E D G
Sbjct: 235 EEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGS 294
Query: 168 EEKVEE 173
+EK +E
Sbjct: 295 DEKKKE 300
Score = 27.7 bits (60), Expect = 5.9
Identities = 14/56 (25%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Query: 126 EEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQR 181
EE++ E ++ E E++++ E ++++ EK+G K + +++ E DT+ Q+
Sbjct: 7 EEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRM-ESTDTKRQK 61
Score = 27.7 bits (60), Expect = 5.9
Identities = 18/72 (25%), Positives = 29/72 (40%), Gaps = 2/72 (2%)
Query: 109 ECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEE--EKEEEKEEDEEEEEKEGKKM 166
E A+ P E + E + + KEE EE E +E+ +
Sbjct: 141 ERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTEN 200
Query: 167 EEEKVEEEIDTE 178
EEE VEE+++ +
Sbjct: 201 EEEGVEEDVEED 212
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 66.2 bits (160), Expect = 1e-11
Identities = 35/74 (47%), Positives = 49/74 (66%)
Query: 111 SAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEK 170
S +QG E EE EE+ E+EE EE+ EEDEE +E EE+EE+EEEEE+E ++ EEE
Sbjct: 191 SDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEY 250
Query: 171 VEEEIDTEIQRTQY 184
++E D + + Y
Sbjct: 251 EQDERDQKEEGNDY 264
Score = 64.3 bits (155), Expect = 6e-11
Identities = 30/65 (46%), Positives = 48/65 (73%)
Query: 113 QQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVE 172
++G+ + EE EE EE+ EE+E+ +E E+EEEEE+EEE+EE+EEEEE E + ++++
Sbjct: 202 EEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEG 261
Query: 173 EEIDT 177
+ DT
Sbjct: 262 NDYDT 266
Score = 60.8 bits (146), Expect = 6e-10
Identities = 31/66 (46%), Positives = 45/66 (68%), Gaps = 6/66 (9%)
Query: 119 EEEEVEEEEEEVEE------EEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVE 172
E+EEVEE+ EE EE EE+EEE+EE+EEEEE+EEE E+DE ++++EG +
Sbjct: 211 EDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEA 270
Query: 173 EEIDTE 178
+ +E
Sbjct: 271 SDSGSE 276
Score = 56.2 bits (134), Expect = 2e-08
Identities = 31/73 (42%), Positives = 45/73 (61%)
Query: 111 SAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEK 170
+ G E+ E EEE EE+ EE++E +E+ EE EE E+ EEEEE+E ++ EEE+
Sbjct: 185 TGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEE 244
Query: 171 VEEEIDTEIQRTQ 183
EEE + +R Q
Sbjct: 245 EEEEEYEQDERDQ 257
Score = 53.5 bits (127), Expect = 1e-07
Identities = 25/58 (43%), Positives = 42/58 (72%), Gaps = 1/58 (1%)
Query: 119 EEEEVEEE-EEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEI 175
E+EEV+E+ EEE EEEE+EEE+EE+EEEE +++E+++ EE + + + + E +
Sbjct: 221 EDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESV 278
Score = 52.8 bits (125), Expect = 2e-07
Identities = 25/63 (39%), Positives = 42/63 (66%)
Query: 109 ECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEE 168
E A++ V+E+ EEEEEE EEEE+EEE+EE+ E++E+++++E ++ + E
Sbjct: 216 EEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGS 275
Query: 169 EKV 171
E V
Sbjct: 276 ESV 278
Score = 47.4 bits (111), Expect = 7e-06
Identities = 27/87 (31%), Positives = 53/87 (60%), Gaps = 2/87 (2%)
Query: 100 ARTAALVAEECSAQQ-GLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEE 158
+R++ EE ++++ G E +E+ E EEE E++ EE++E E++ +E+E
Sbjct: 164 SRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDE 223
Query: 159 E-EKEGKKMEEEKVEEEIDTEIQRTQY 184
E +++G++ EEE+ EEE + E + +Y
Sbjct: 224 EVDEDGEEEEEEEEEEEEEEEEEEEEY 250
Score = 45.1 bits (105), Expect = 4e-05
Identities = 23/66 (34%), Positives = 34/66 (51%)
Query: 113 QQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVE 172
+ G EEEE EEEEEE EEEE+ E+ E D++EE + + + + E + V
Sbjct: 227 EDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVR 286
Query: 173 EEIDTE 178
T+
Sbjct: 287 SGSGTD 292
Score = 28.1 bits (61), Expect = 4.5
Identities = 16/66 (24%), Positives = 28/66 (42%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKME 167
EE ++ EEEE E++E + +EE + + + + E D G
Sbjct: 235 EEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGS 294
Query: 168 EEKVEE 173
+EK +E
Sbjct: 295 DEKKKE 300
Score = 27.7 bits (60), Expect = 5.9
Identities = 14/56 (25%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Query: 126 EEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQR 181
EE++ E ++ E E++++ E ++++ EK+G K + +++ E DT+ Q+
Sbjct: 7 EEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRM-ESTDTKRQK 61
Score = 27.7 bits (60), Expect = 5.9
Identities = 18/72 (25%), Positives = 29/72 (40%), Gaps = 2/72 (2%)
Query: 109 ECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEE--EKEEEKEEDEEEEEKEGKKM 166
E A+ P E + E + + KEE EE E +E+ +
Sbjct: 141 ERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTEN 200
Query: 167 EEEKVEEEIDTE 178
EEE VEE+++ +
Sbjct: 201 EEEGVEEDVEED 212
>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
Length = 587
Score = 65.5 bits (158), Expect = 3e-11
Identities = 30/47 (63%), Positives = 40/47 (85%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKK 165
+E+E EEEE E EEEE EEE+EEDEEEEE+EEE+EE+E ++ +G+K
Sbjct: 360 DEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEK 406
Score = 63.2 bits (152), Expect = 1e-10
Identities = 28/47 (59%), Positives = 41/47 (87%)
Query: 118 VEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGK 164
+ ++E EEEEEE EEEE+E E+EE+E+EEE+EEE+EE+EEE ++ G+
Sbjct: 357 LSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQ 403
Score = 60.1 bits (144), Expect = 1e-09
Identities = 28/46 (60%), Positives = 38/46 (82%)
Query: 124 EEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEE 169
E+EEEE E EE+EEE EE+EEE+E+EEE+EE+EEEEE + + E+
Sbjct: 361 EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEK 406
Score = 59.3 bits (142), Expect = 2e-09
Identities = 27/47 (57%), Positives = 40/47 (85%)
Query: 124 EEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEK 170
+E+EEE EE E+EEE+ E+EEEE++EEE+EE+EEEEE+ ++ + EK
Sbjct: 360 DEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEK 406
Score = 57.4 bits (137), Expect = 7e-09
Identities = 27/53 (50%), Positives = 38/53 (71%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKV 171
+EEE EE EEE EE E+EEE++E+EEEEE+EEE+EE ++ + E K+
Sbjct: 362 DEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKI 414
Score = 57.0 bits (136), Expect = 9e-09
Identities = 37/93 (39%), Positives = 52/93 (55%), Gaps = 22/93 (23%)
Query: 99 VARTAALVAEECSAQQ---------GLPVEEEEVEEEEEEVE-------------EEEKE 136
+ R AAL E A + G + EE E+ +E +E +E++E
Sbjct: 305 IKRDAALAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDDEDEE 364
Query: 137 EEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEE 169
EE+E +EEEEE EEE+EEDEEEEE+E ++ EEE
Sbjct: 365 EEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEE 397
Score = 54.3 bits (129), Expect = 6e-08
Identities = 24/48 (50%), Positives = 39/48 (81%)
Query: 126 EEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEE 173
++E+ EEEE+ EE+EE+ EEEE+E+E+EE+EEEEE+E + + + E+
Sbjct: 359 DDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEK 406
Score = 53.5 bits (127), Expect = 1e-07
Identities = 25/51 (49%), Positives = 40/51 (78%)
Query: 127 EEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDT 177
++E EEEE+E E+EE+E EEE+EE++EE+EEEEE+E ++ ++ E+ T
Sbjct: 359 DDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSAT 409
Score = 52.4 bits (124), Expect = 2e-07
Identities = 28/57 (49%), Positives = 38/57 (66%), Gaps = 2/57 (3%)
Query: 119 EEEEVEEEEEEVEEEEKE--EEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEE 173
EEEE EEEEEE EEEE+E EE+EE+EEEEE+E ++ E+ +K+ + E
Sbjct: 365 EEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTGE 421
Score = 48.9 bits (115), Expect = 2e-06
Identities = 24/57 (42%), Positives = 40/57 (70%)
Query: 98 SVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEE 154
++A+ A ++++ ++ EEEE E EEEE E+EE+EEE+EE+EEEE ++ + E
Sbjct: 349 NMAKVLASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGE 405
Score = 47.8 bits (112), Expect = 5e-06
Identities = 25/59 (42%), Positives = 37/59 (62%)
Query: 103 AALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEK 161
A+L +E ++ EEEE EEEEE +EEE+EEE+EE+EEE ++ + E+ K
Sbjct: 355 ASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRK 413
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 65.1 bits (157), Expect = 3e-11
Identities = 30/39 (76%), Positives = 37/39 (94%)
Query: 124 EEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKE 162
EEEEEE E+EE+EEE EE+EEEEE+EEE+EE+EEEEE+E
Sbjct: 733 EEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 64.7 bits (156), Expect = 4e-11
Identities = 30/40 (75%), Positives = 38/40 (95%)
Query: 121 EEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEE 160
+E EEEEEE EEEE+E+E+EE+EEEEE+EEE+EE+EEEEE
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 64.3 bits (155), Expect = 6e-11
Identities = 29/46 (63%), Positives = 41/46 (89%)
Query: 117 PVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKE 162
PV+ + +EEEE EEE++EEE+E++EEEEE+EEE+EE+EEEEE+E
Sbjct: 724 PVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEE 769
Score = 64.3 bits (155), Expect = 6e-11
Identities = 30/40 (75%), Positives = 37/40 (92%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEE 158
+EEE EEEE+E EEEE EEE+EE+EEEEE+EEE+EE+EEE
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 63.9 bits (154), Expect = 7e-11
Identities = 29/40 (72%), Positives = 38/40 (95%)
Query: 120 EEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEE 159
+EE EEEEE+ EEEE++EE+EE+EEEEE+EEE+EE+EEEE
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 63.2 bits (152), Expect = 1e-10
Identities = 29/45 (64%), Positives = 39/45 (86%)
Query: 117 PVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEK 161
P + EEEEEE +EEE+EE++EE+EEEEE+EEE+EE+EEEEE+
Sbjct: 727 PQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 63.2 bits (152), Expect = 1e-10
Identities = 28/39 (71%), Positives = 38/39 (97%)
Query: 124 EEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKE 162
+EEEEE EE+E+EEE++E+EEEEE+EEE+EE+EEEEE+E
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 770
Score = 60.1 bits (144), Expect = 1e-09
Identities = 28/47 (59%), Positives = 39/47 (82%)
Query: 123 VEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEE 169
V+ + EEEE+EEE EE+EEE+E+EEE+EE+EEEEE+E ++ EEE
Sbjct: 725 VQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 60.1 bits (144), Expect = 1e-09
Identities = 28/41 (68%), Positives = 36/41 (87%)
Query: 115 GLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEED 155
G EEEE E+EEEE E+EE+EEE+EE+EEEEE+EEE+EE+
Sbjct: 731 GKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 58.2 bits (139), Expect = 4e-09
Identities = 26/52 (50%), Positives = 42/52 (80%)
Query: 116 LPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKME 167
+P+ + + +E EEEE+E+E+EE+E+EEE+EEE+EE+EEEEE+E ++ E
Sbjct: 720 VPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 58.2 bits (139), Expect = 4e-09
Identities = 26/46 (56%), Positives = 39/46 (84%)
Query: 127 EEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVE 172
+ + +E+EEE+EEDEEEEE++EE+EE+EEEEE+E ++ EEE+ E
Sbjct: 726 QPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 58.2 bits (139), Expect = 4e-09
Identities = 26/40 (65%), Positives = 37/40 (92%)
Query: 135 KEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEE 174
KEEE+EE+E+EEE+EE++EE+EEEEE+E ++ EEE+ EEE
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 56.2 bits (134), Expect = 2e-08
Identities = 27/40 (67%), Positives = 34/40 (85%)
Query: 139 KEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
KEE+EEEEE EEE+EEDEEEEE+E ++ EEE+ EEE + E
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 55.5 bits (132), Expect = 3e-08
Identities = 27/49 (55%), Positives = 38/49 (77%)
Query: 104 ALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEK 152
A V + + ++ EEE+ EEEEE+ EEEE+EEE+EE+EEEEE+EEE+
Sbjct: 723 APVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 55.1 bits (131), Expect = 3e-08
Identities = 24/40 (60%), Positives = 37/40 (92%)
Query: 134 EKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEE 173
++EEE+EE++EEEE+E+E+EE+EEEEE+E ++ EEE+ EE
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 54.3 bits (129), Expect = 6e-08
Identities = 24/45 (53%), Positives = 38/45 (84%)
Query: 130 VEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEE 174
V+ + +E+EE+EEE+E+EEE++E+EEEEE+E ++ EEE+ EEE
Sbjct: 725 VQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEE 769
Score = 43.5 bits (101), Expect = 1e-04
Identities = 19/41 (46%), Positives = 33/41 (80%)
Query: 138 EKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
+ + + +EEE+EEE++E+EEEE++E ++ EEE+ EEE + E
Sbjct: 726 QPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEE 766
>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
3 [Homo sapiens]
Length = 526
Score = 65.1 bits (157), Expect = 3e-11
Identities = 35/73 (47%), Positives = 47/73 (64%), Gaps = 1/73 (1%)
Query: 107 AEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEK-EEDEEEEEKEGKK 165
AE SA+ G EEEE EEEEEE E EE +EE+EEEEE+EEE EE E+ ++
Sbjct: 23 AESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 82
Query: 166 MEEEKVEEEIDTE 178
+ EE++ E+ + E
Sbjct: 83 VSEEEMSEDEERE 95
Score = 58.9 bits (141), Expect = 2e-09
Identities = 31/77 (40%), Positives = 44/77 (57%)
Query: 98 SVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEE 157
S +T++ + + G EEEE EEEEEE E+ EE+EE+EEEEE+E +E
Sbjct: 16 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEA 75
Query: 158 EEEKEGKKMEEEKVEEE 174
E+ + EEE E+E
Sbjct: 76 SEQSAEEVSEEEMSEDE 92
Score = 46.6 bits (109), Expect = 1e-05
Identities = 29/76 (38%), Positives = 39/76 (51%), Gaps = 11/76 (14%)
Query: 114 QGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEK---------EEEKEEDEEEEEKEGK 164
Q + E + E E E+EE+EEEEE+ EEE+EE+EEEEE+ G
Sbjct: 11 QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGS 70
Query: 165 KMEE--EKVEEEIDTE 178
EE E+ EE+ E
Sbjct: 71 NSEEASEQSAEEVSEE 86
Score = 44.3 bits (103), Expect = 6e-05
Identities = 29/68 (42%), Positives = 33/68 (48%), Gaps = 12/68 (17%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEK-----------EGKKME 167
EEEE EEEEEE E EE E EE EEE EDEE E + + E
Sbjct: 56 EEEEEEEEEEE-ETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 114
Query: 168 EEKVEEEI 175
E+ EEE+
Sbjct: 115 SEEAEEEV 122
Score = 43.1 bits (100), Expect = 1e-04
Identities = 22/68 (32%), Positives = 38/68 (55%), Gaps = 3/68 (4%)
Query: 118 VEEEEVEEEEEEVEEEEKEEEKEEDEEEEE---KEEEKEEDEEEEEKEGKKMEEEKVEEE 174
+EE ++ + +++ + E++ E E EEE+EE+EEEEE+ E E+ EEE
Sbjct: 1 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 60
Query: 175 IDTEIQRT 182
+ E + T
Sbjct: 61 EEEEEEET 68
Score = 33.1 bits (74), Expect = 0.14
Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 7/86 (8%)
Query: 107 AEECSAQQGLPVEEEEVEEEEEEVEEE------EKEEEKEEDEEEEEKEEEKEEDEEEEE 160
+EE S Q V EEE+ E+EE E E +++ E EE +EE E +
Sbjct: 72 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSA 131
Query: 161 -KEGKKMEEEKVEEEIDTEIQRTQYL 185
EG + + I+ + + +YL
Sbjct: 132 LTEGDYVPDSPALSPIELKQELPKYL 157
>gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Homo
sapiens]
Length = 1108
Score = 63.9 bits (154), Expect = 7e-11
Identities = 38/82 (46%), Positives = 56/82 (68%), Gaps = 2/82 (2%)
Query: 106 VAEECSAQQGLPVEEEEV-EEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGK 164
V S QG E E + EE+E+ E+EE+EE+KE +E +EEKE EK + +EEEE+E +
Sbjct: 995 VGARASPSQGDSDERESLTREEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEE 1054
Query: 165 KMEEEKVEE-EIDTEIQRTQYL 185
++EEE+VEE E + E +T+ L
Sbjct: 1055 EVEEEEVEEAENEGEEAKTEGL 1076
Score = 56.2 bits (134), Expect = 2e-08
Identities = 31/68 (45%), Positives = 45/68 (66%), Gaps = 6/68 (8%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKE------EDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVE 172
E+ E EEEEE+ E EE +EEKE ++EEEEE+EE +EE+ EE E EG++ + E +
Sbjct: 1018 EDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAKTEGLM 1077
Query: 173 EEIDTEIQ 180
++ E Q
Sbjct: 1078 KDDRAESQ 1085
Score = 47.8 bits (112), Expect = 5e-06
Identities = 32/74 (43%), Positives = 43/74 (58%), Gaps = 7/74 (9%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKE-GKKM 166
+EC QG +EE EEEEEEVEEEE EE + E EE + + K++ E + G+K+
Sbjct: 1038 KECEKPQG----DEEEEEEEEEVEEEEVEEAENEGEEAKTEGLMKDDRAESQASSLGQKV 1093
Query: 167 EE--EKVEEEIDTE 178
E E+V EE E
Sbjct: 1094 GESSEQVSEEKTNE 1107
Score = 31.6 bits (70), Expect = 0.41
Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 2/61 (3%)
Query: 125 EEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEE--EKVEEEIDTEIQRT 182
EE + E+EE E +E + + D +E E ++ +E EK EEE D E++
Sbjct: 975 EERDSTEQEEAGPEILSNEHVGARASPSQGDSDERESLTREEDEDSEKEEEEEDKEMEEL 1034
Query: 183 Q 183
Q
Sbjct: 1035 Q 1035
>gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Homo
sapiens]
Length = 1124
Score = 63.9 bits (154), Expect = 7e-11
Identities = 38/82 (46%), Positives = 56/82 (68%), Gaps = 2/82 (2%)
Query: 106 VAEECSAQQGLPVEEEEV-EEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGK 164
V S QG E E + EE+E+ E+EE+EE+KE +E +EEKE EK + +EEEE+E +
Sbjct: 1011 VGARASPSQGDSDERESLTREEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEE 1070
Query: 165 KMEEEKVEE-EIDTEIQRTQYL 185
++EEE+VEE E + E +T+ L
Sbjct: 1071 EVEEEEVEEAENEGEEAKTEGL 1092
Score = 56.2 bits (134), Expect = 2e-08
Identities = 31/68 (45%), Positives = 45/68 (66%), Gaps = 6/68 (8%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKE------EDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVE 172
E+ E EEEEE+ E EE +EEKE ++EEEEE+EE +EE+ EE E EG++ + E +
Sbjct: 1034 EDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAKTEGLM 1093
Query: 173 EEIDTEIQ 180
++ E Q
Sbjct: 1094 KDDRAESQ 1101
Score = 47.8 bits (112), Expect = 5e-06
Identities = 32/74 (43%), Positives = 43/74 (58%), Gaps = 7/74 (9%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKE-GKKM 166
+EC QG +EE EEEEEEVEEEE EE + E EE + + K++ E + G+K+
Sbjct: 1054 KECEKPQG----DEEEEEEEEEVEEEEVEEAENEGEEAKTEGLMKDDRAESQASSLGQKV 1109
Query: 167 EE--EKVEEEIDTE 178
E E+V EE E
Sbjct: 1110 GESSEQVSEEKTNE 1123
Score = 31.6 bits (70), Expect = 0.41
Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 2/61 (3%)
Query: 125 EEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEE--EKVEEEIDTEIQRT 182
EE + E+EE E +E + + D +E E ++ +E EK EEE D E++
Sbjct: 991 EERDSTEQEEAGPEILSNEHVGARASPSQGDSDERESLTREEDEDSEKEEEEEDKEMEEL 1050
Query: 183 Q 183
Q
Sbjct: 1051 Q 1051
>gi|28274705 family with sequence similarity 9, member A [Homo
sapiens]
Length = 332
Score = 63.9 bits (154), Expect = 7e-11
Identities = 37/80 (46%), Positives = 52/80 (65%), Gaps = 5/80 (6%)
Query: 98 SVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEE-----EK 152
+ A AA +A + + VE+EE EE+EEE E+EE+EEE EE+ EE EE E
Sbjct: 199 AAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEG 258
Query: 153 EEDEEEEEKEGKKMEEEKVE 172
EE EEEEE+E ++ EEE+++
Sbjct: 259 EETEEEEEEEEEEEEEEQIK 278
Score = 63.2 bits (152), Expect = 1e-10
Identities = 42/90 (46%), Positives = 50/90 (55%), Gaps = 19/90 (21%)
Query: 100 ARTAALVAEECSAQQGLPVEEE----EVEEEEEEVEEEEKEEEKEEDEEE---------- 145
A AA AE +A + E E EEEEE+ EEEEKEEE+EE EEE
Sbjct: 194 AEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGG 253
Query: 146 -----EEKEEEKEEDEEEEEKEGKKMEEEK 170
EE EEE+EE+EEEEE+E K +EK
Sbjct: 254 GGGEGEETEEEEEEEEEEEEEEQIKAFQEK 283
Score = 39.3 bits (90), Expect = 0.002
Identities = 21/60 (35%), Positives = 37/60 (61%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
E EE EEEEEE EEEE+EE+ + +E++++ ++ +E K + E+ ++ DT+
Sbjct: 257 EGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLREMKPLLEQLLKAAKDTK 316
Score = 34.7 bits (78), Expect = 0.048
Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 2/69 (2%)
Query: 106 VAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKK 165
V +E A++ E EE E E E E E+E+EE++EEEE+ K+
Sbjct: 177 VLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEE--KE 234
Query: 166 MEEEKVEEE 174
EEE+ EEE
Sbjct: 235 EEEEEGEEE 243
Score = 33.9 bits (76), Expect = 0.082
Identities = 25/66 (37%), Positives = 32/66 (48%), Gaps = 17/66 (25%)
Query: 127 EEEVEEEEKEEEKEEDEEEEEKEEEKE--------------EDEEEEEKEGKKMEEEKVE 172
+E + E++K++E EE E E EDEEEEEKE EEEK E
Sbjct: 179 KEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKE---EEEEKEE 235
Query: 173 EEIDTE 178
EE + E
Sbjct: 236 EEEEGE 241
>gi|22749303 hypothetical protein LOC196477 [Homo sapiens]
Length = 406
Score = 63.2 bits (152), Expect = 1e-10
Identities = 38/66 (57%), Positives = 47/66 (71%), Gaps = 2/66 (3%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKME 167
E C A++ EEEEVE+EEEEVE+EE EEE EE E EE EEE EE+E EEE+E +
Sbjct: 293 EVCDAKEASE-EEEEVEDEEEEVEDEE-EEEVEEAEYVEEGEEELEEEELEEEEEVLEEN 350
Query: 168 EEKVEE 173
E++ EE
Sbjct: 351 EQRGEE 356
Score = 56.2 bits (134), Expect = 2e-08
Identities = 34/58 (58%), Positives = 41/58 (70%), Gaps = 6/58 (10%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKE--EEKEEDEEEEEKEGKKMEEEKVEEE 174
+ +E EEEEEVE+EE+E E EE+EE EE E EE EE+ EEEE E EEE+V EE
Sbjct: 296 DAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELE----EEEEVLEE 349
Score = 55.5 bits (132), Expect = 3e-08
Identities = 53/185 (28%), Positives = 87/185 (47%), Gaps = 18/185 (9%)
Query: 11 RKPPPSHATGVSTQSFQILGREGWRVKPAHTLLAMTSQRNKELRPSTCLEVEEKWLQRWA 70
R PP +T G R P T M +Q +++R +E +++ L+
Sbjct: 160 RSPPADVSTLPRPVKLYEWREPGMRAPPNTTQFIM-NQIYEDMRQQEKVERQQEALRAQK 218
Query: 71 VGL-----PVKDSGVS-----QAKIWGKNDLSAGNRLSVARTAALVAEECSAQQGLPVEE 120
+ P + SG + WG + G + + + EE + L VEE
Sbjct: 219 ATVSGEASPARSSGNDAPPGGSKETWGLQETLYGFVQNPSLAFSPNPEENQSLAPLLVEE 278
Query: 121 EEVE--EEEEEVEEE-----EKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEE 173
EE + ++EEE ++E E EE+EE E+EEE+ E++EE+E EE + ++ EEE EE
Sbjct: 279 EEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEE 338
Query: 174 EIDTE 178
E++ E
Sbjct: 339 ELEEE 343
Score = 49.3 bits (116), Expect = 2e-06
Identities = 30/57 (52%), Positives = 38/57 (66%), Gaps = 2/57 (3%)
Query: 107 AEECSAQQGLPVEEEEVE--EEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEK 161
A+E S ++ +EEE EEEEEVEE E EE EE+ EEEE EEE+E EE E++
Sbjct: 297 AKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQR 353
Score = 48.1 bits (113), Expect = 4e-06
Identities = 22/52 (42%), Positives = 36/52 (69%)
Query: 134 EKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQYL 185
E+EEEK+ D+EEE +E + E EE+E + EEE+VE+E + E++ +Y+
Sbjct: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYV 328
Score = 43.5 bits (101), Expect = 1e-04
Identities = 29/60 (48%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 100 ARTAALVAEECSAQQGLPVEEEEVE-EEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEE 158
A+ A+ EE ++ +EEE E EE E VEE E+E E+EE EEEEE EE E+ EE
Sbjct: 297 AKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEE 356
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 62.8 bits (151), Expect = 2e-10
Identities = 37/64 (57%), Positives = 44/64 (68%), Gaps = 4/64 (6%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEK----EEEKEEDEEEEEKEGKKMEEEKVEEE 174
EEEE EEEEEE EE E EEE+EE EEEEE+ EE EE+E EEE + EEE+ +EE
Sbjct: 406 EEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEE 465
Query: 175 IDTE 178
+E
Sbjct: 466 SSSE 469
Score = 58.2 bits (139), Expect = 4e-09
Identities = 36/59 (61%), Positives = 42/59 (71%), Gaps = 5/59 (8%)
Query: 120 EEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
+ E EEEEEE EEEE+EEE E +EEEEE EEE+EE E EE EEE+VEEE D +
Sbjct: 402 KSEGEEEEEE-EEEEEEEEGEGEEEEEEGEEEEEEGGEGEELG----EEEEVEEEGDVD 455
Score = 53.5 bits (127), Expect = 1e-07
Identities = 34/77 (44%), Positives = 46/77 (59%), Gaps = 4/77 (5%)
Query: 102 TAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEK----EEDEEEEEKEEEKEEDEE 157
T +L +E ++ EEEE E EEE EE E+EEE+ EE EEEE EEE + D +
Sbjct: 398 TTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSD 457
Query: 158 EEEKEGKKMEEEKVEEE 174
EEE+E ++ E +E E
Sbjct: 458 EEEEEDEESSSEGLEAE 474
Score = 37.0 bits (84), Expect = 0.010
Identities = 22/73 (30%), Positives = 38/73 (52%), Gaps = 6/73 (8%)
Query: 82 QAKIWGKNDLSAGNRLSVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEE 141
+A+ W + + AG S A +C L E E+ + + EEE+ EEE +E
Sbjct: 472 EAEDWAQGVVEAGG--SFGAYGAQEEAQCPTLHFL----EGGEDSDSDSEEEDDEEEDDE 525
Query: 142 DEEEEEKEEEKEE 154
DE++++ EE+ +E
Sbjct: 526 DEDDDDDEEDGDE 538
Score = 36.6 bits (83), Expect = 0.013
Identities = 33/127 (25%), Positives = 50/127 (39%), Gaps = 55/127 (43%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEV--------EEEEKEEEKEEDEEEEEKEEEK------- 152
EE ++G EEEE EEEEE EEEE EEE + D +EEE+E+E+
Sbjct: 413 EEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLE 472
Query: 153 ----------------------------------------EEDEEEEEKEGKKMEEEKVE 172
+ +EE++E+E + E++ +
Sbjct: 473 AEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDD 532
Query: 173 EEIDTEI 179
EE E+
Sbjct: 533 EEDGDEV 539
Score = 35.8 bits (81), Expect = 0.022
Identities = 13/41 (31%), Positives = 29/41 (70%)
Query: 126 EEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKM 166
E+ + + EE+++E+E+DE+E++ ++E++ DE G+ M
Sbjct: 508 EDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGEAM 548
>gi|55741661 hypothetical protein LOC57653 [Homo sapiens]
Length = 1646
Score = 62.0 bits (149), Expect = 3e-10
Identities = 30/57 (52%), Positives = 43/57 (75%)
Query: 118 VEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEE 174
+ EE V+ + E+ EE E+E+EKEE+EEEE+ EEEKEE E +EE+E + EE+ +EE
Sbjct: 891 LNEENVKGQGEKKEESEEEDEKEEEEEEEKLEEEKEEKEAQEEQESLSVGEEEDKEE 947
Score = 54.7 bits (130), Expect = 4e-08
Identities = 36/75 (48%), Positives = 48/75 (64%), Gaps = 12/75 (16%)
Query: 114 QGLPVEEEEVEEE--------EEEV--EEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEG 163
QGL EE +VE E EE V + E+KEE +EEDE+EEE+EEEK E+E+EE++
Sbjct: 874 QGL--EEMQVEREGSLNPSLNEENVKGQGEKKEESEEEDEKEEEEEEEKLEEEKEEKEAQ 931
Query: 164 KKMEEEKVEEEIDTE 178
++ E V EE D E
Sbjct: 932 EEQESLSVGEEEDKE 946
Score = 53.9 bits (128), Expect = 8e-08
Identities = 25/52 (48%), Positives = 41/52 (78%)
Query: 124 EEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEI 175
E++EE EE+EKEEE+EE++ EEEKEE++ ++E+E G++ ++E+ EEI
Sbjct: 901 EKKEESEEEDEKEEEEEEEKLEEEKEEKEAQEEQESLSVGEEEDKEEGLEEI 952
Score = 53.5 bits (127), Expect = 1e-07
Identities = 27/56 (48%), Positives = 39/56 (69%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEG 163
EE QG EE E E+E+EE EEEEK EE++E++E +E++E EEE+++EG
Sbjct: 893 EENVKGQGEKKEESEEEDEKEEEEEEEKLEEEKEEKEAQEEQESLSVGEEEDKEEG 948
Score = 44.3 bits (103), Expect = 6e-05
Identities = 27/82 (32%), Positives = 48/82 (58%), Gaps = 1/82 (1%)
Query: 97 LSVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDE 156
L + + L A+ +++G EE++ E E EE + + E+++E E+E+++
Sbjct: 853 LGQQKKSPLHAKMDESKEGSIQGLEEMQVEREGSLNPSLNEENVKGQGEKKEESEEEDEK 912
Query: 157 EEEEKEGKKMEEEKVEEEIDTE 178
EEEE+E +K+EEEK E+E E
Sbjct: 913 EEEEEE-EKLEEEKEEKEAQEE 933
Score = 42.4 bits (98), Expect = 2e-04
Identities = 23/58 (39%), Positives = 34/58 (58%)
Query: 126 EEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQ 183
EE +VE E +E + + E+KEE EEE+EKE ++ EE+ EE+ + E Q Q
Sbjct: 877 EEMQVEREGSLNPSLNEENVKGQGEKKEESEEEDEKEEEEEEEKLEEEKEEKEAQEEQ 934
Score = 32.0 bits (71), Expect = 0.31
Identities = 28/117 (23%), Positives = 54/117 (46%), Gaps = 14/117 (11%)
Query: 76 KDSGVSQAKIWGKNDLSAGNRLSVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEK 135
K G + + +S+G S AR+ V EE + + EE + ++++ +
Sbjct: 808 KKQGSKEDMTRSEESISSGT--STARSVEEVEEENDQEMESFITEEVLGQQKKSPLHAKM 865
Query: 136 EEEKEE-----DEEEEEKE-------EEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQ 180
+E KE +E + E+E E+ + E+KE + E+EK EEE + +++
Sbjct: 866 DESKEGSIQGLEEMQVEREGSLNPSLNEENVKGQGEKKEESEEEDEKEEEEEEEKLE 922
Score = 31.2 bits (69), Expect = 0.53
Identities = 16/58 (27%), Positives = 31/58 (53%)
Query: 123 VEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQ 180
V+E + EE++K EK +D+ ++ +E E + EE+ +EE+D+ I+
Sbjct: 1421 VKEIRGQFEEQQKRLEKRKDKNAQKLHLNLGHPVHFQEMESLHLSEEERQEELDSMIR 1478
Score = 30.8 bits (68), Expect = 0.69
Identities = 20/42 (47%), Positives = 28/42 (66%), Gaps = 3/42 (7%)
Query: 119 EEEEVEEEEEE-VEEEEKEEEK--EEDEEEEEKEEEKEEDEE 157
EEE++EEE+EE +EE+E EE+++EE EE ED E
Sbjct: 917 EEEKLEEEKEEKEAQEEQESLSVGEEEDKEEGLEEIYYEDME 958
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 62.0 bits (149), Expect = 3e-10
Identities = 29/45 (64%), Positives = 39/45 (86%)
Query: 114 QGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEE 158
Q L + +E EEEEEE +EEE+EEE+EE+E+EEE+EEE+EE+EEE
Sbjct: 1060 QLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEE 1104
Score = 61.2 bits (147), Expect = 5e-10
Identities = 28/50 (56%), Positives = 41/50 (82%)
Query: 111 SAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEE 160
+ ++G +E + EEEE EE+E+EEE+EE+EEE+E+EEE+EE+EEEEE
Sbjct: 1055 TGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEE 1104
Score = 61.2 bits (147), Expect = 5e-10
Identities = 30/56 (53%), Positives = 40/56 (71%)
Query: 116 LPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKV 171
L E E EEEEE+ EEEE+EEE+EEDEEEEE+EEE+EE+E + + + + V
Sbjct: 1064 LSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSV 1119
Score = 61.2 bits (147), Expect = 5e-10
Identities = 30/58 (51%), Positives = 41/58 (70%)
Query: 124 EEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQR 181
+E EE EEEE EEE+EE+EEEEE EEE+EE+EEEEE+E + ++ + I+R
Sbjct: 1066 KESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKR 1123
Score = 60.5 bits (145), Expect = 8e-10
Identities = 37/92 (40%), Positives = 55/92 (59%), Gaps = 9/92 (9%)
Query: 80 VSQAKIWGKNDLS-----AGNRLSVARTAA----LVAEECSAQQGLPVEEEEVEEEEEEV 130
+ QA W K + A +R S A+ + L + E G + E+ +E E
Sbjct: 1012 MEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEE 1071
Query: 131 EEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKE 162
EEEE++EE+EE+EEEEE++EE+EE+EEEEE+E
Sbjct: 1072 EEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEE 1103
Score = 55.5 bits (132), Expect = 3e-08
Identities = 33/68 (48%), Positives = 43/68 (63%), Gaps = 6/68 (8%)
Query: 117 PVEEEEVEEEEEEVEEEEKEEEKE-----EDEEEEEKEEEKEEDEEEEEKE-GKKMEEEK 170
P EEEE EEEEEE EEEE+ EE+E E + + K +EKEE E EKE ++++ +
Sbjct: 1350 PEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHE 1409
Query: 171 VEEEIDTE 178
EEE D E
Sbjct: 1410 EEEEEDEE 1417
Score = 52.8 bits (125), Expect = 2e-07
Identities = 32/81 (39%), Positives = 45/81 (55%), Gaps = 16/81 (19%)
Query: 119 EEEEVEEEEEEVEEEE------------KEEEKEEDEEEEEKEE----EKEEDEEEEEKE 162
EEEE EEEEEE EEEE K +EKEE E EKE+ + E+EEEE++E
Sbjct: 1358 EEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEE 1417
Query: 163 GKKMEEEKVEEEIDTEIQRTQ 183
E+ ++E D+ ++ +
Sbjct: 1418 PSHNEDHDADDEDDSHMESAE 1438
Score = 50.8 bits (120), Expect = 6e-07
Identities = 27/58 (46%), Positives = 38/58 (65%)
Query: 121 EEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
E+ E++ + EEEE+EEE+EE+EEEEE+ EE+E E+ +EK E EI TE
Sbjct: 1341 EKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTE 1398
Score = 45.1 bits (105), Expect = 4e-05
Identities = 24/58 (41%), Positives = 36/58 (62%)
Query: 126 EEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQ 183
E V E + + E EE+EEE++E+EEEEE+E ++ EEE+ EEE + E + Q
Sbjct: 1050 ESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQ 1107
Score = 41.2 bits (95), Expect = 5e-04
Identities = 23/72 (31%), Positives = 37/72 (51%)
Query: 109 ECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEE 168
E S ++ ++ EEEEEE EE E+ + D+E++ E E ++EE +E K
Sbjct: 1394 EISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVL 1453
Query: 169 EKVEEEIDTEIQ 180
E E +D +Q
Sbjct: 1454 ENQETFLDLNVQ 1465
Score = 40.4 bits (93), Expect = 9e-04
Identities = 29/68 (42%), Positives = 40/68 (58%), Gaps = 16/68 (23%)
Query: 120 EEEVEEEEEEV--EEEEKEEEK-----------EEDEEEEEKEEEKEEDEEEEEKEGKKM 166
EEEV+E E + +EE + EE E+ E++ K EE+EE+EEEEE+E
Sbjct: 1308 EEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEE---E 1364
Query: 167 EEEKVEEE 174
EEE+ EEE
Sbjct: 1365 EEEEGEEE 1372
Score = 32.3 bits (72), Expect = 0.24
Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKME 167
+E SA+ EEEE +EE E+ + ++ E+D E E EKEE E KE + +
Sbjct: 1399 KEDSARLDDHEEEEEEDEEPSHNEDHDADD--EDDSHMESAEVEKEELPRESFKEVLENQ 1456
Query: 168 E 168
E
Sbjct: 1457 E 1457
Score = 29.3 bits (64), Expect = 2.0
Identities = 27/93 (29%), Positives = 38/93 (40%), Gaps = 31/93 (33%)
Query: 117 PVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEE-------------------------- 150
P+E +E EE+ E E + EEE +E
Sbjct: 1280 PMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSP 1339
Query: 151 -EKEEDE----EEEEKEGKKMEEEKVEEEIDTE 178
EK ED+ EEEE+E ++ EEE+ EEE + E
Sbjct: 1340 GEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEE 1372
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 61.6 bits (148), Expect = 4e-10
Identities = 36/78 (46%), Positives = 46/78 (58%), Gaps = 7/78 (8%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEE-------EEEKEEEKEEDEEEEE 160
EE S P +E+E +EE + EEEE EEE E+D+E EEE+EEE+EE+EEEEE
Sbjct: 108 EEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEE 167
Query: 161 KEGKKMEEEKVEEEIDTE 178
E +M DTE
Sbjct: 168 NEDHQMNCHNTRIMQDTE 185
Score = 58.5 bits (140), Expect = 3e-09
Identities = 30/74 (40%), Positives = 50/74 (67%), Gaps = 3/74 (4%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKE--EEKEEDEE-EEEKEEEKEEDEEEEEKEGK 164
+EC G +E+ E+E EE E+ E +E EEDEE + E+EEE EE++E+++++G+
Sbjct: 88 DECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGE 147
Query: 165 KMEEEKVEEEIDTE 178
+E+E+ EEE + E
Sbjct: 148 DVEDEEEEEEEEEE 161
Score = 57.0 bits (136), Expect = 9e-09
Identities = 26/61 (42%), Positives = 46/61 (75%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
+ +E +E+EE EE ++EEE+E +EE+E+ +E+ E+ E+EEE+E ++ EEE+ EE D +
Sbjct: 113 DNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQ 172
Query: 179 I 179
+
Sbjct: 173 M 173
Score = 53.9 bits (128), Expect = 8e-08
Identities = 29/68 (42%), Positives = 45/68 (66%), Gaps = 1/68 (1%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKE-EEKEEDEEEEEKEEEKEEDEEEEEKEGKKM 166
+E +G E+ E +E+ E+EE + EE+EE EEE+E ++E ED E+EE+E ++
Sbjct: 100 DEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEE 159
Query: 167 EEEKVEEE 174
EEE+ EEE
Sbjct: 160 EEEEEEEE 167
Score = 52.8 bits (125), Expect = 2e-07
Identities = 28/79 (35%), Positives = 49/79 (62%), Gaps = 1/79 (1%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEE-EKEEDEEEEEKEGKKM 166
EE ++ +E +E+EE+ E + +EEE+ E+E+E++ E+ E EDEEEEE+E ++
Sbjct: 103 EEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEE 162
Query: 167 EEEKVEEEIDTEIQRTQYL 185
EEE+ E+ T+ +
Sbjct: 163 EEEEENEDHQMNCHNTRIM 181
Score = 52.4 bits (124), Expect = 2e-07
Identities = 27/74 (36%), Positives = 49/74 (66%), Gaps = 3/74 (4%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKE---EEKEEDEEEEEKEEEKEEDEEEEEKEGK 164
E+ ++G EEEE+EEE+E+ +E+ ++ EE+EE+EEEEE+EEE+ ED + +
Sbjct: 120 EDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTR 179
Query: 165 KMEEEKVEEEIDTE 178
M++ + ++ + E
Sbjct: 180 IMQDTEKDDNNNDE 193
Score = 47.0 bits (110), Expect = 9e-06
Identities = 21/61 (34%), Positives = 42/61 (68%)
Query: 118 VEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDT 177
V+E + + E+++E+E++E +E E+ +E +E EEDEE + +E +++EEE +++ D
Sbjct: 87 VDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDG 146
Query: 178 E 178
E
Sbjct: 147 E 147
Score = 42.4 bits (98), Expect = 2e-04
Identities = 20/53 (37%), Positives = 33/53 (62%)
Query: 121 EEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEE 173
E+VE+EEEE EEEE+EEE+EE+E+ + ++ E+ + E + +E
Sbjct: 147 EDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199
Score = 36.2 bits (82), Expect = 0.017
Identities = 22/60 (36%), Positives = 34/60 (56%), Gaps = 3/60 (5%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKME 167
+E + G VE+EE EEEEEE EEE+EEE+ ED + +D E+++ + +
Sbjct: 139 DEDDDEDGEDVEDEE-EEEEEE--EEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYD 195
>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
sapiens]
Length = 631
Score = 61.2 bits (147), Expect = 5e-10
Identities = 31/60 (51%), Positives = 44/60 (73%), Gaps = 4/60 (6%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEE----EEKEGKKMEEEKVEEE 174
EE E EEE+EE++EE EEE+EE+EEEEE+EEE+EE+EE+ + G E+ +EE+
Sbjct: 109 EETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEED 168
Score = 50.8 bits (120), Expect = 6e-07
Identities = 30/77 (38%), Positives = 48/77 (62%), Gaps = 6/77 (7%)
Query: 105 LVAEECSAQQGLPVEEEEVEEE---EEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEK 161
LV EE + ++ E+EE++EE EEE EEEE+EEE+EE+EEEEE+ + +
Sbjct: 105 LVGEEETEREE---EDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHE 161
Query: 162 EGKKMEEEKVEEEIDTE 178
+ E++ +EE + +E
Sbjct: 162 QYSLEEDQALEEWVSSE 178
Score = 43.5 bits (101), Expect = 1e-04
Identities = 23/43 (53%), Positives = 30/43 (69%)
Query: 139 KEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQR 181
+EE E EEE EE +EE EEEE+E ++ EEE+ EEE + E R
Sbjct: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPR 150
Score = 38.9 bits (89), Expect = 0.003
Identities = 20/41 (48%), Positives = 28/41 (68%)
Query: 143 EEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQ 183
EEE E+EEE EE +EE +E ++ EEE+ EEE + E + Q
Sbjct: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQ 148
>gi|21735569 claspin [Homo sapiens]
Length = 1339
Score = 61.2 bits (147), Expect = 5e-10
Identities = 35/65 (53%), Positives = 45/65 (69%), Gaps = 2/65 (3%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKV--EEEID 176
EEEE EEEE E EE EEK E EE+EE+ EE+EE EEEEE+EG + E + EEI+
Sbjct: 629 EEEEEEEEEMTDESEEDGEEKVEKEEKEEELEEEEEKEEEEEEEGNQETAEFLLSSEEIE 688
Query: 177 TEIQR 181
T+ ++
Sbjct: 689 TKDEK 693
Score = 55.8 bits (133), Expect = 2e-08
Identities = 33/64 (51%), Positives = 44/64 (68%), Gaps = 4/64 (6%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEED-EEEEEKEEEKEEDEEEEEKEGKKMEEE---KVEEE 174
EEE +E EE+ EE+ ++EEKEE+ EEEEEKEEE+EE+ +E E EE K E+E
Sbjct: 635 EEEMTDESEEDGEEKVEKEEKEEELEEEEEKEEEEEEEGNQETAEFLLSSEEIETKDEKE 694
Query: 175 IDTE 178
+D E
Sbjct: 695 MDKE 698
Score = 51.2 bits (121), Expect = 5e-07
Identities = 34/69 (49%), Positives = 44/69 (63%), Gaps = 18/69 (26%)
Query: 119 EEEEVEEE---------EEEVEEEEKEEEKEEDEE-EEEKEEEKEED--------EEEEE 160
EEEE EEE EE+VE+EEKEEE EE+EE EEE+EEE ++ EE E
Sbjct: 630 EEEEEEEEMTDESEEDGEEKVEKEEKEEELEEEEEKEEEEEEEGNQETAEFLLSSEEIET 689
Query: 161 KEGKKMEEE 169
K+ K+M++E
Sbjct: 690 KDEKEMDKE 698
Score = 45.8 bits (107), Expect = 2e-05
Identities = 26/56 (46%), Positives = 35/56 (62%)
Query: 118 VEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEE 173
VE+EE EEE EE EE+E+EEE+E ++E E EE E ++EKE K + E
Sbjct: 650 VEKEEKEEELEEEEEKEEEEEEEGNQETAEFLLSSEEIETKDEKEMDKENNDGSSE 705
Score = 42.7 bits (99), Expect = 2e-04
Identities = 35/120 (29%), Positives = 62/120 (51%), Gaps = 12/120 (10%)
Query: 71 VGLPVKDSGVSQAKIWGKNDLSAGN-RLSVARTAALVAEECSAQQGLPVEEEEVEEEEEE 129
V + VKD G GK +L A +++A A + L V + +++E +
Sbjct: 553 VNVIVKDMGTD-----GKEELKADVVPVTLAPKKLDGASHTKPGEKLQVLKAKLQEAMKL 607
Query: 130 VEEEEKEEEK------EEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQ 183
EE+++ + ED EEE+EEE+E +E EE +K+E+E+ EEE++ E ++ +
Sbjct: 608 RRFEERQKRQALFKLDNEDGFEEEEEEEEEMTDESEEDGEEKVEKEEKEEELEEEEEKEE 667
Score = 41.2 bits (95), Expect = 5e-04
Identities = 25/60 (41%), Positives = 35/60 (58%), Gaps = 6/60 (10%)
Query: 107 AEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEE------DEEEEEKEEEKEEDEEEEE 160
+EE ++ E+EE EEEEE EEEE+EE +E EE E ++EKE D+E +
Sbjct: 642 SEEDGEEKVEKEEKEEELEEEEEKEEEEEEEGNQETAEFLLSSEEIETKDEKEMDKENND 701
Score = 37.0 bits (84), Expect = 0.010
Identities = 22/55 (40%), Positives = 32/55 (58%), Gaps = 2/55 (3%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKE--EEKEEDEEEEEKEEEKEEDEEEEE 160
E+ ++ L EEE+ EEEEEE +E E EE E ++EKE +KE ++ E
Sbjct: 651 EKEEKEEELEEEEEKEEEEEEEGNQETAEFLLSSEEIETKDEKEMDKENNDGSSE 705
Score = 35.0 bits (79), Expect = 0.037
Identities = 17/63 (26%), Positives = 34/63 (53%), Gaps = 4/63 (6%)
Query: 117 PVEEEEVEEEEE----EVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVE 172
P ++EE +EEEE + + E + +EDE + + ED E++++E EK++
Sbjct: 986 PTDKEEEDEEEEFGDFRLVSNDNEFDSDEDEHSDSGNDLALEDHEDDDEEELLKRSEKLK 1045
Query: 173 EEI 175
++
Sbjct: 1046 RQM 1048
Score = 30.0 bits (66), Expect = 1.2
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 2/84 (2%)
Query: 98 SVARTAALVAEECSAQQGLPVEEEEV--EEEEEEVEEEEKEEEKEEDEEEEEKEEEKEED 155
S ++ L +E + G P+EE +EEE EEE+ D + E + D
Sbjct: 954 STPASSELNKQEKESSMGDPMEEALALCSGSFPTDKEEEDEEEEFGDFRLVSNDNEFDSD 1013
Query: 156 EEEEEKEGKKMEEEKVEEEIDTEI 179
E+E G + E E++ + E+
Sbjct: 1014 EDEHSDSGNDLALEDHEDDDEEEL 1037
Score = 30.0 bits (66), Expect = 1.2
Identities = 19/74 (25%), Positives = 40/74 (54%), Gaps = 4/74 (5%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEE--EEEKEEEKEEDEEEEEKEGKK 165
E + L +E+ E ++EEE ++ EK + + + E+E E + E+E +G++
Sbjct: 1016 EHSDSGNDLALEDHEDDDEEELLKRSEKLKRQMRLRKYLEDEAEVSGSDVGSEDEYDGEE 1075
Query: 166 MEEEKVEEEIDTEI 179
++E EE++ E+
Sbjct: 1076 IDE--YEEDVIDEV 1087
Score = 29.3 bits (64), Expect = 2.0
Identities = 16/64 (25%), Positives = 35/64 (54%)
Query: 120 EEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEI 179
E+E E +V E++ + +E DE EE+ +E +EE + + KK+ + + ++ ++
Sbjct: 1055 EDEAEVSGSDVGSEDEYDGEEIDEYEEDVIDEVLPSDEELQSQIKKIHMKTMLDDDKRQL 1114
Query: 180 QRTQ 183
+ Q
Sbjct: 1115 RLYQ 1118
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 61.2 bits (147), Expect = 5e-10
Identities = 57/173 (32%), Positives = 77/173 (44%), Gaps = 42/173 (24%)
Query: 43 LAMTSQRNKELRPSTCLEVEEKWLQRWAVGLPVKDSGVSQAKIWGKNDLSAGNRLSVART 102
L SQR R L K LQ V +P KDS + I+ + ++
Sbjct: 407 LLTKSQREARARAEATL----KLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKE 462
Query: 103 AALVAEECSA----QQGLPVEEEE---VEEEEEEVEEE---------------------- 133
+ E C+A +QG+P +EE VE EEEE E+
Sbjct: 463 VSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNK 522
Query: 134 ---EKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKK------MEEEKVEEEIDT 177
E +E EE+EEEEE+EEE EE EEEEE+EG+ E+EKV +E D+
Sbjct: 523 VHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDS 575
Score = 57.8 bits (138), Expect = 5e-09
Identities = 33/77 (42%), Positives = 49/77 (63%), Gaps = 11/77 (14%)
Query: 118 VEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEK------EGKKMEEEKV 171
+E +E EEEEE EEEE+E+E+ E+EEEEE E E E +EE+EK GK ++++
Sbjct: 525 IEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPS 584
Query: 172 EE-----EIDTEIQRTQ 183
+E E D++ RT+
Sbjct: 585 KEMSSDSEYDSDDDRTK 601
Score = 45.4 bits (106), Expect = 3e-05
Identities = 23/60 (38%), Positives = 38/60 (63%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
EEEE + EE+E + KEEE+ E E+ E K+++++E +E +KEGK + + + E E
Sbjct: 361 EEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAE 420
Score = 43.5 bits (101), Expect = 1e-04
Identities = 23/74 (31%), Positives = 45/74 (60%), Gaps = 18/74 (24%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEE------------------DEEEEEKEEEKEEDEEEEE 160
++++ ++++++ E+EEKE+EK++ +EEE +K EE+E + EE
Sbjct: 312 DKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEE 371
Query: 161 KEGKKMEEEKVEEE 174
E K+ EEE++E+E
Sbjct: 372 LEAKRKEEERLEQE 385
Score = 43.1 bits (100), Expect = 1e-04
Identities = 24/69 (34%), Positives = 42/69 (60%)
Query: 113 QQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVE 172
Q+ L +EE E ++ E EE K E+ E + +EE+ E+E+ E +++KE ++ E K E
Sbjct: 345 QEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKE 404
Query: 173 EEIDTEIQR 181
++ T+ QR
Sbjct: 405 GKLLTKSQR 413
Score = 40.4 bits (93), Expect = 9e-04
Identities = 20/61 (32%), Positives = 40/61 (65%)
Query: 118 VEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDT 177
++E + +EEE ++ +EEE+ + EE E + ++EE E+E++E KK +E++ +E +
Sbjct: 344 MQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKK 403
Query: 178 E 178
E
Sbjct: 404 E 404
Score = 40.0 bits (92), Expect = 0.001
Identities = 21/67 (31%), Positives = 36/67 (53%)
Query: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKME 167
EE ++ EEEE EE E E E ++E+EK DE++ K +K+ +E +
Sbjct: 537 EEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSD 596
Query: 168 EEKVEEE 174
+++ +EE
Sbjct: 597 DDRTKEE 603
Score = 37.4 bits (85), Expect = 0.007
Identities = 15/61 (24%), Positives = 40/61 (65%)
Query: 118 VEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDT 177
V +++ E++E E ++ ++E+ K +E+E+ E ++D+ ++++ +K EEE V+ ++
Sbjct: 228 VAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTV 287
Query: 178 E 178
+
Sbjct: 288 D 288
Score = 37.4 bits (85), Expect = 0.007
Identities = 23/85 (27%), Positives = 46/85 (54%), Gaps = 18/85 (21%)
Query: 119 EEEEVEEEEEEVEEEEKE------------------EEKEEDEEEEEKEEEKEEDEEEEE 160
++++ + E+EE E+E+K+ EE+E + EEE+ ++ E+ E +
Sbjct: 317 DKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKR 376
Query: 161 KEGKKMEEEKVEEEIDTEIQRTQYL 185
KE +++E+EK E + E +R + L
Sbjct: 377 KEEERLEQEKRERKKQKEKERKERL 401
Score = 37.4 bits (85), Expect = 0.007
Identities = 21/80 (26%), Positives = 40/80 (50%), Gaps = 17/80 (21%)
Query: 119 EEEEVEEEEEEVEEEEKE-----------------EEKEEDEEEEEKEEEKEEDEEEEEK 161
EEEE EEE+EE EEEE+E +EK+ + ++K ++ + E +
Sbjct: 536 EEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDS 595
Query: 162 EGKKMEEEKVEEEIDTEIQR 181
+ + +EE+ ++ I++
Sbjct: 596 DDDRTKEERAYDKAKRRIEK 615
Score = 36.2 bits (82), Expect = 0.017
Identities = 28/121 (23%), Positives = 57/121 (47%), Gaps = 19/121 (15%)
Query: 84 KIWGKNDLSAGNR-LSVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEED 142
K+ K +L G + S + + EE + + + V+ + EE+ E E+ E
Sbjct: 252 KLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEG 311
Query: 143 EEEEEKEEEKEEDEEEEEKEGK------------------KMEEEKVEEEIDTEIQRTQY 184
+++++ +++K+ ++EE+EKE K K EEE+ + E + I+R +
Sbjct: 312 DKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEE 371
Query: 185 L 185
L
Sbjct: 372 L 372
Score = 32.3 bits (72), Expect = 0.24
Identities = 21/71 (29%), Positives = 40/71 (56%), Gaps = 7/71 (9%)
Query: 108 EECSAQ-QGLPVEEEEV-----EEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEK 161
EE S + QG+ + E V E EEE ++K+++ ++ +++ + + EE E+++ K
Sbjct: 63 EELSLEAQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSK 122
Query: 162 EGKKMEEEKVE 172
KK + KVE
Sbjct: 123 -SKKTAKPKVE 132
Score = 30.8 bits (68), Expect = 0.69
Identities = 14/47 (29%), Positives = 28/47 (59%)
Query: 118 VEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGK 164
+E + EEE E E+ E++++KE++ +E K+E K + + E +
Sbjct: 372 LEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARAR 418
Score = 30.4 bits (67), Expect = 0.91
Identities = 23/97 (23%), Positives = 48/97 (49%), Gaps = 2/97 (2%)
Query: 74 PVKDSGVSQAKIWGKNDLSAGNRLSVARTAALVAEECSA-QQGLPVEEEEVEEEEEEVEE 132
P K G + K K D + L +L A+ A ++ + V+ E EEE ++
Sbjct: 37 PQKSKG-KKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKD 95
Query: 133 EEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEE 169
++K+ +K + + ++ + E+ ED++ + K+ K + E
Sbjct: 96 KKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVE 132
Score = 28.9 bits (63), Expect = 2.6
Identities = 26/101 (25%), Positives = 43/101 (42%), Gaps = 4/101 (3%)
Query: 76 KDSGVSQAKIWGKNDLSAGNRLSVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEK 135
K G S+A + + A + R E + L + +E E E+E E +K
Sbjct: 332 KKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKK 391
Query: 136 EEEKEEDE--EEEEKEEEKEEDEEEEEKEG--KKMEEEKVE 172
++EKE E ++E K K + E E K ++ + VE
Sbjct: 392 QKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVE 432
Score = 28.5 bits (62), Expect = 3.4
Identities = 16/81 (19%), Positives = 44/81 (54%), Gaps = 9/81 (11%)
Query: 107 AEECSAQQGLPVEEEEVEEEEEEVEE-------EEKEEEKEEDEEEEEKEEEKEEDEEEE 159
+EE ++G E EE+E+ +E ++K ++ + E + ++++ ++E
Sbjct: 547 SEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAY 606
Query: 160 EKEGKKMEEEKVE--EEIDTE 178
+K +++E+ ++E + ++TE
Sbjct: 607 DKAKRRIEKRRLEHSKNVNTE 627
Score = 27.7 bits (60), Expect = 5.9
Identities = 13/69 (18%), Positives = 39/69 (56%)
Query: 109 ECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEE 168
E S + + ++ E E +E++ ++ + +++E+K+++ +ED+ +E E +E
Sbjct: 10 EDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEA 69
Query: 169 EKVEEEIDT 177
+ ++ + +T
Sbjct: 70 QGIKADRET 78
Score = 27.3 bits (59), Expect = 7.7
Identities = 16/63 (25%), Positives = 33/63 (52%), Gaps = 4/63 (6%)
Query: 123 VEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEE----KEGKKMEEEKVEEEIDTE 178
+E E+ + K + + + E+++ E K+ DEE+ + KE +++E K ++ E
Sbjct: 212 IESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKE 271
Query: 179 IQR 181
QR
Sbjct: 272 SQR 274
>gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo
sapiens]
Length = 142
Score = 60.8 bits (146), Expect = 6e-10
Identities = 33/63 (52%), Positives = 43/63 (68%), Gaps = 3/63 (4%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
EE+ EE+ E + EKEEEKEE+EEEEE+EEE+EE+EEEEE E+ E +TE
Sbjct: 79 EEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRER---ETETE 135
Query: 179 IQR 181
+R
Sbjct: 136 EKR 138
Score = 57.8 bits (138), Expect = 5e-09
Identities = 27/55 (49%), Positives = 39/55 (70%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEE 173
+ E + EE+ EE++ EEK + + EKEEEKEE+EEEEE+E ++ EEE+ EE
Sbjct: 66 QRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120
Score = 55.5 bits (132), Expect = 3e-08
Identities = 30/65 (46%), Positives = 42/65 (64%), Gaps = 1/65 (1%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
E+ E+ EE EEK E + E+EEEKEEE EE+EEEEE+E ++ EEE+V + T
Sbjct: 70 EKRREEKRREEKRREEKRREGKRREKEEEKEEE-EEEEEEEEEEEEEEEEEEVSFSLATR 128
Query: 179 IQRTQ 183
+ T+
Sbjct: 129 ERETE 133
Score = 53.9 bits (128), Expect = 8e-08
Identities = 25/67 (37%), Positives = 44/67 (65%)
Query: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
EE+ EE+ E + E + ++E+E+EEE+EEE+EE+EEEEE+E +++ E +TE
Sbjct: 74 EEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETE 133
Query: 179 IQRTQYL 185
+ + +
Sbjct: 134 TEEKRLI 140
Score = 46.6 bits (109), Expect = 1e-05
Identities = 24/53 (45%), Positives = 37/53 (69%), Gaps = 2/53 (3%)
Query: 126 EEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
EE+ EE+ +EE++ E++ E K EKEE E+EE+E ++ EEE+ EEE + E
Sbjct: 69 EEKRREEKRREEKRREEKRREGKRREKEE--EKEEEEEEEEEEEEEEEEEEEE 119
Score = 44.7 bits (104), Expect = 5e-05
Identities = 21/55 (38%), Positives = 37/55 (67%), Gaps = 1/55 (1%)
Query: 131 EEEEKEEEKEEDEEEEEKEEE-KEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQY 184
EE+ +EE++ E++ EEK E K ++EEE++E ++ EEE+ EEE + E + +
Sbjct: 69 EEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSF 123
Score = 43.9 bits (102), Expect = 8e-05
Identities = 23/76 (30%), Positives = 37/76 (48%)
Query: 103 AALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKE 162
A L S ++ P + + +E+ +EE EE++ EEK + + EKE
Sbjct: 37 AGLTNSTSSVKEEPPTLRHSMAGTSARKSQRREEKRREEKRREEKRREEKRREGKRREKE 96
Query: 163 GKKMEEEKVEEEIDTE 178
+K EEE+ EEE + E
Sbjct: 97 EEKEEEEEEEEEEEEE 112
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.301 0.122 0.328
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,251,467
Number of Sequences: 37866
Number of extensions: 635485
Number of successful extensions: 107252
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2285
Number of HSP's successfully gapped in prelim test: 436
Number of HSP's that attempted gapping in prelim test: 10701
Number of HSP's gapped (non-prelim): 37978
length of query: 185
length of database: 18,247,518
effective HSP length: 96
effective length of query: 89
effective length of database: 14,612,382
effective search space: 1300501998
effective search space used: 1300501998
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.