Guide to the Human Genome
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Search of human proteins with 169207312

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169207312 PREDICTED: hypothetical protein [Homo sapiens]
         (414 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169207312 PREDICTED: hypothetical protein [Homo sapiens]           860   0.0  
gi|239750650 PREDICTED: hypothetical protein [Homo sapiens]           860   0.0  
gi|89037350 PREDICTED: hypothetical protein [Homo sapiens]            860   0.0  
gi|163965366 nascent polypeptide-associated complex alpha subuni...    87   4e-17
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    76   5e-14
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    76   5e-14
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]       65   1e-10
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]       65   1e-10
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    64   2e-10
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     64   3e-10
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    62   7e-10
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             61   2e-09
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    61   2e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    60   3e-09
gi|169160903 PREDICTED: hypothetical protein [Homo sapiens]            60   3e-09
gi|48375167 microtubule-associated protein 6 isoform 2 [Homo sap...    60   4e-09
gi|48375173 microtubule-associated protein 6 isoform 1 [Homo sap...    60   4e-09
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    60   5e-09
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    60   5e-09
gi|160707881 formin 2 [Homo sapiens]                                   59   6e-09
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          57   2e-08
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          57   2e-08
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          57   2e-08
gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H...    57   2e-08
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         57   2e-08
gi|47132519 Ras association and pleckstrin homology domains 1 is...    57   3e-08
gi|153281158 dual specificity phosphatase 8 [Homo sapiens]             57   3e-08
gi|182507165 thymus expressed gene 3-like [Homo sapiens]               57   4e-08
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...    57   4e-08
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         57   4e-08

>gi|169207312 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 414

 Score =  860 bits (2222), Expect = 0.0
 Identities = 414/414 (100%), Positives = 414/414 (100%)

Query: 1   MSELESGEIRSEEGRPTTESRIRPRLAEALSQPTLRHSASALRPPRLSRGKDLKPRCGRG 60
           MSELESGEIRSEEGRPTTESRIRPRLAEALSQPTLRHSASALRPPRLSRGKDLKPRCGRG
Sbjct: 1   MSELESGEIRSEEGRPTTESRIRPRLAEALSQPTLRHSASALRPPRLSRGKDLKPRCGRG 60

Query: 61  PAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP 120
           PAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP
Sbjct: 61  PAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP 120

Query: 121 PRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPG 180
           PRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPG
Sbjct: 121 PRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPG 180

Query: 181 PQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRT 240
           PQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRT
Sbjct: 181 PQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRT 240

Query: 241 RPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPR 300
           RPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPR
Sbjct: 241 RPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPR 300

Query: 301 ADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDE 360
           ADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDE
Sbjct: 301 ADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDE 360

Query: 361 PRRVVIAARECGREGSELPPSGEETPGRRKSPSQSCKKGGESILHSVVCLVGDF 414
           PRRVVIAARECGREGSELPPSGEETPGRRKSPSQSCKKGGESILHSVVCLVGDF
Sbjct: 361 PRRVVIAARECGREGSELPPSGEETPGRRKSPSQSCKKGGESILHSVVCLVGDF 414


>gi|239750650 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 414

 Score =  860 bits (2222), Expect = 0.0
 Identities = 414/414 (100%), Positives = 414/414 (100%)

Query: 1   MSELESGEIRSEEGRPTTESRIRPRLAEALSQPTLRHSASALRPPRLSRGKDLKPRCGRG 60
           MSELESGEIRSEEGRPTTESRIRPRLAEALSQPTLRHSASALRPPRLSRGKDLKPRCGRG
Sbjct: 1   MSELESGEIRSEEGRPTTESRIRPRLAEALSQPTLRHSASALRPPRLSRGKDLKPRCGRG 60

Query: 61  PAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP 120
           PAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP
Sbjct: 61  PAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP 120

Query: 121 PRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPG 180
           PRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPG
Sbjct: 121 PRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPG 180

Query: 181 PQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRT 240
           PQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRT
Sbjct: 181 PQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRT 240

Query: 241 RPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPR 300
           RPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPR
Sbjct: 241 RPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPR 300

Query: 301 ADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDE 360
           ADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDE
Sbjct: 301 ADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDE 360

Query: 361 PRRVVIAARECGREGSELPPSGEETPGRRKSPSQSCKKGGESILHSVVCLVGDF 414
           PRRVVIAARECGREGSELPPSGEETPGRRKSPSQSCKKGGESILHSVVCLVGDF
Sbjct: 361 PRRVVIAARECGREGSELPPSGEETPGRRKSPSQSCKKGGESILHSVVCLVGDF 414


>gi|89037350 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 414

 Score =  860 bits (2222), Expect = 0.0
 Identities = 414/414 (100%), Positives = 414/414 (100%)

Query: 1   MSELESGEIRSEEGRPTTESRIRPRLAEALSQPTLRHSASALRPPRLSRGKDLKPRCGRG 60
           MSELESGEIRSEEGRPTTESRIRPRLAEALSQPTLRHSASALRPPRLSRGKDLKPRCGRG
Sbjct: 1   MSELESGEIRSEEGRPTTESRIRPRLAEALSQPTLRHSASALRPPRLSRGKDLKPRCGRG 60

Query: 61  PAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP 120
           PAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP
Sbjct: 61  PAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP 120

Query: 121 PRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPG 180
           PRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPG
Sbjct: 121 PRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPG 180

Query: 181 PQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRT 240
           PQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRT
Sbjct: 181 PQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRT 240

Query: 241 RPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPR 300
           RPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPR
Sbjct: 241 RPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPR 300

Query: 301 ADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDE 360
           ADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDE
Sbjct: 301 ADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDE 360

Query: 361 PRRVVIAARECGREGSELPPSGEETPGRRKSPSQSCKKGGESILHSVVCLVGDF 414
           PRRVVIAARECGREGSELPPSGEETPGRRKSPSQSCKKGGESILHSVVCLVGDF
Sbjct: 361 PRRVVIAARECGREGSELPPSGEETPGRRKSPSQSCKKGGESILHSVVCLVGDF 414


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 117/430 (27%), Positives = 153/430 (35%), Gaps = 70/430 (16%)

Query: 13   EGRPTTESRIRPRLAEALSQPTLRHSAS--ALRPPRLSRGKDLKPRCGRGP----AHSPD 66
            +G PTT +   P      + P+L+ + +  A  PP   +G    P     P    A  P 
Sbjct: 1054 KGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPS-PKGGPATPSPKGAPMPPAATPPS 1112

Query: 67   PGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVR-PPPRGRV 125
            P  G        A   P     SP+  LA+ P +       A  P P  G+  PPP+G  
Sbjct: 1113 PKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKG-- 1170

Query: 126  GLSQAPGRPLGACARAKGIRLVNPSP------PRPPEPIPASAAVTSGLTARGPNTSATP 179
                AP  P       KG  L  PSP      P    P P     T          +ATP
Sbjct: 1171 ----APTTPAATPPSPKG-GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1225

Query: 180  GPQKGRGSAERTNHIPKDKQRVAAPPPPER-PRVPFCRGSSGLSVPTPPEHAGGRRKKFT 238
               KG  +       P      A PP P+  P  P  +G+      TPP   GG      
Sbjct: 1226 PSPKGGLATPSPKGAPTTP--AATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPH 1283

Query: 239  RTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSP 298
            +  P P   +     PS +   ATS    AP P   +P   PSP+ +P     + G  +P
Sbjct: 1284 KGAPNPAVVT----PPSPKGGPATSPPKGAPTPPAATP---PSPKGSPGTPPPK-GAPTP 1335

Query: 299  PRAD------------TGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRR 346
            P               T  SS GG + P SK    P PPA T     G    P       
Sbjct: 1336 PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEG--PTPPAATPSHKGGPAMTP------- 1386

Query: 347  GPGPAQGP--PSRRDEPRRVVIA--------ARECGREGSELPPSGEETP------GRRK 390
             P P +GP  PS + +P    +         A    REG+  P  G+ TP        +K
Sbjct: 1387 -PSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKK 1445

Query: 391  SPSQSCKKGG 400
            +P+ S  KGG
Sbjct: 1446 APATSAPKGG 1455



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 104/369 (28%), Positives = 124/369 (33%), Gaps = 74/369 (20%)

Query: 61   PAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP 120
            PA +P   +G  A     A  +P+ AS  P A   S  G           P   +   P 
Sbjct: 1012 PAVTPPSPKGSPA-----ATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS 1066

Query: 121  PRG---RVGLSQAPGRPLGACARAKGIRLVNPSP---PRPPEPIPAS------------A 162
            P+G      L  AP  P       KG     PSP   P PP   P S            A
Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKG-GPATPSPKGAPMPPAATPPSPKGGLATPPHKGA 1125

Query: 163  AVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSS--- 219
              T   T   P       P KG  +       P  K  +A PPP   P  P     S   
Sbjct: 1126 PTTPAATPPSPKGGLATPPPKGAPTTPAATP-PSPKGGLATPPPKGAPTTPAATPPSPKG 1184

Query: 220  GLSVP-----------TPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSA 268
            GL+ P           TPP   GG      +  P    ++     PS +   AT S   A
Sbjct: 1185 GLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT----PPSPKGGLATPSPKGA 1240

Query: 269  PLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPA---PP 325
            P     +P   PSP+  PA    + G  +PP A T  S  GG + P  K    PA   PP
Sbjct: 1241 PTTPAATP---PSPKGGPATPPPK-GAPTPPAA-TPPSLKGGLATPPHKGAPNPAVVTPP 1295

Query: 326  APTAWPAAGAP-GAPNPAESRRGPGPAQGPPSRRDEPRRVVIAARECGREGSELPPSGEE 384
            +P   PA   P GAP P        PA  PPS +  P                 PP G  
Sbjct: 1296 SPKGGPATSPPKGAPTP--------PAATPPSPKGSP--------------GTPPPKGAP 1333

Query: 385  TPGRRKSPS 393
            TP     PS
Sbjct: 1334 TPPAVTPPS 1342



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 75/275 (27%), Positives = 98/275 (35%), Gaps = 19/275 (6%)

Query: 85   PASLSPRAALA-SAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACARAKG 143
            PA+ +P+ A A S     P+ AR    P+ +     P       +  P  P G  A    
Sbjct: 900  PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSP 959

Query: 144  IRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAA 203
                 P+PP    P P     T          +ATP   KG  +       P        
Sbjct: 960  KWA--PTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPP 1017

Query: 204  PPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPR--TSSFLSEVPSTRPLCA 261
             P       PF +G+S     TPP   G          PLP+   ++  + +PS +   A
Sbjct: 1018 SPKGSPAATPFPKGASTPPAATPPSPKGS-----PAATPLPKGAPTTPAATLPSPKGGPA 1072

Query: 262  TSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTL 321
            T S   AP P   +P   PSP+  PA    + G   PP A T  S  GG + P  K    
Sbjct: 1073 TPSLKGAPTPPAATP---PSPKGGPATPSPK-GAPMPPAA-TPPSPKGGLATPPHK---- 1123

Query: 322  PAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPS 356
             AP  P A P +   G   P        PA  PPS
Sbjct: 1124 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1158



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 98/452 (21%), Positives = 146/452 (32%), Gaps = 84/452 (18%)

Query: 11   SEEGRPTTESRI--RPRLAEALSQPTLRHSASALRPPRLSRGKDLKPRCGRGPAHSPDPG 68
            S +G PTT +     P+   A   P    +  A  PP L  G    P  G     +P+P 
Sbjct: 1236 SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKG-----APNPA 1290

Query: 69   EGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGL- 127
                   +      P   + +P AA   +P   P        P P +   P P+G   L 
Sbjct: 1291 VVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLP 1350

Query: 128  ---------------SQAPGRPLGACARAKGIRLVNPSPPRPPE-PIPASAAVTSGLTAR 171
                            + P  P    +   G  +  PSP R P  P P     +  +   
Sbjct: 1351 ATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPL 1410

Query: 172  GPNTS-ATPGPQKGRGSAERTNHIPKD------KQRVAAPPPPERPRVPFCRGSSGLSVP 224
             P  + ATP  ++G  +  + +  P        K+  A   P   P  P  +G   L   
Sbjct: 1411 SPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAV 1470

Query: 225  TPPEHAGGRRKKFTRTRPLPRTS-----------------SFLSEVPST-----RPLCAT 262
            TPP        K   T   P+ +                 S   EVP+T      P+  T
Sbjct: 1471 TPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPT 1530

Query: 263  SSSHSAPLPFFWSP--------LRNPSPRPAPACGELRLGRLSP-------PRADTGGSS 307
            ++  S   P   +P        +  PSP+  PA    +    +P       P A T  + 
Sbjct: 1531 ATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTY 1590

Query: 308  SGGCSGPDSKHRTLP----------APPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSR 357
             G    P  K   +P          AP  P   P +   G   PA       P   P S 
Sbjct: 1591 KG---APSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSL 1647

Query: 358  RDEPRRVVIAARECGREGSELPPSGEETPGRR 389
            +D P     A+  C + G+ +P + +  P ++
Sbjct: 1648 KDSPTSP--ASVTC-KMGATVPQASKGLPAKK 1676



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 61/247 (24%), Positives = 93/247 (37%), Gaps = 28/247 (11%)

Query: 154  PPEPIPASAAVTSGLTARG----PNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPP--- 206
            P  P+ AS    + L+ +G    P T+ +P P   +G+   +   P   + V  PP    
Sbjct: 827  PVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETP 886

Query: 207  -PERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSS 265
             P    +PF +   G + P P +         + T   P+ +      P+ + + A+ S 
Sbjct: 887  TPSVVNLPFPK--EGPATPAPKQAPA-----LSMTSSSPKKAR---ATPAPKGIPASPSP 936

Query: 266  HSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPP 325
              AP P   +P   PSP+  PA    +     P  A T  S  GG + P  K     AP 
Sbjct: 937  KGAPTPPAATP---PSPKGGPATPSPKWAPTPP--AATPPSPKGGPATPSPKG----APT 987

Query: 326  APTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDEPRRVVIAARECGREGSELPPSGEET 385
             P A P +   G   P+       PA  PPS +  P       +      +  PPS + +
Sbjct: 988  PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPF-PKGASTPPAATPPSPKGS 1046

Query: 386  PGRRKSP 392
            P     P
Sbjct: 1047 PAATPLP 1053



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 75/306 (24%), Positives = 108/306 (35%), Gaps = 30/306 (9%)

Query: 85   PASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGR------PLGAC 138
            PA+ +P+   A+ P  K  P   A  P   S   PP   +V  S +P +      P+GA 
Sbjct: 1447 PATSAPKGGPAT-PSSKGDPTLPAVTPP--SPKEPPAPKQVATSSSPKKAPATPAPMGAP 1503

Query: 139  ARAKGIRLVNPSPPRPPEPIPASAA--VTSGLTARGPNTSATPGPQKGRGSAERTNHIPK 196
                 +  V PS P+     P+S    +    T     T AT  P++       T  +P 
Sbjct: 1504 T----LPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMT--VPS 1557

Query: 197  DKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPST 256
             K+  A P P E P  P  + +S     TP  + G    K     P   TS    E P T
Sbjct: 1558 PKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAV-TSPSPKEAP-T 1615

Query: 257  RPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRL-SPPRADTGGSSSGGCSGPD 315
             P     S    P          P+P+  P    +    L   P +    +   G + P 
Sbjct: 1616 PPAVTPPSPEKGP--------ATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQ 1667

Query: 316  SKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDEPRRVVIAARECGREG 375
            +  + LPA   PTA        AP        P   +GP +++       I      + G
Sbjct: 1668 AS-KGLPAKKGPTALKEVLVAPAPESTPIITAP-TRKGPQTKKSSATSPPICPDPSAKNG 1725

Query: 376  SELPPS 381
            S+ P S
Sbjct: 1726 SKGPLS 1731



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 74/293 (25%), Positives = 95/293 (32%), Gaps = 39/293 (13%)

Query: 134 PLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLT--------ARGPNTSATP--GPQK 183
           PL     A  I    PSP  PP   P       G++        A  P    T   G   
Sbjct: 720 PLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASA 779

Query: 184 GRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSG-------LSVPTPPEHAGGRRKK 236
              S     ++      +     P+  R P  +GS+G       LS P  P  A      
Sbjct: 780 TASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEAS----- 834

Query: 237 FTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRN------PSPRPAPACGE 290
           F     L    S   + P+T       S   AP P   +PL        P   P P+   
Sbjct: 835 FLPENSLSFQGS--KDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVN 892

Query: 291 LRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAP-GAPNPAESRRGPG 349
           L   +  P  A      +   S   S  +   A PAP   PA+ +P GAP P  +   P 
Sbjct: 893 LPFPKEGP--ATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTP-PAATPPS 949

Query: 350 PAQGPPSRRDEPRRVVIAARECGREGSELPPS--GEETPGRRKSPSQSCKKGG 400
           P  GP +   +      AA     +G    PS  G  TP     PS    KGG
Sbjct: 950 PKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPS---PKGG 999


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 115/419 (27%), Positives = 145/419 (34%), Gaps = 90/419 (21%)

Query: 33  PTLRHSAS------ALRPPRLSRG------KDLKPRCGRGPAHSPDPGEGCEAWRRLSAD 80
           P LR +A+        RPP L  G      K   P  G G    P PG       R    
Sbjct: 109 PKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGH------RSGPP 162

Query: 81  RWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACAR 140
              R     PR  + S P   P P      PRP+      P  R G    PG P      
Sbjct: 163 EPQRNRMPPPRPDVGSKPDSIPPPVPST--PRPIQS---SPHNR-GSPPVPGGP------ 210

Query: 141 AKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATP-------GPQKGRGSAER--- 190
               R  +P P  PP P     A+  G   + P +S++P        P   R   ++   
Sbjct: 211 ----RQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPP 266

Query: 191 ----TNHIPKDKQRVAAPPPPER-----PRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTR 241
                 + P   +    PPPP+      P  P    SS    P PP    G         
Sbjct: 267 PPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPG-------PP 319

Query: 242 PLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRN------PSPRPAPACGEL--RL 293
           PLP +SS   E P       + SS + PLP   SP R+      PS RP P   +   R 
Sbjct: 320 PLPPSSSGNDETPRLPQRNLSLSSSTPPLP---SPGRSGPLPPPPSERPPPPVRDPPGRS 376

Query: 294 GRLSPPR-ADTGGSSSGGC---------SGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAE 343
           G L PP      GS+S            SG DS  R+ P PP P   P+AGAP  P P+ 
Sbjct: 377 GPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSP-RSGPRPPLPPDRPSAGAPPPPPPST 435

Query: 344 SRRGPGPAQGPPSRRDEPRRVVIAARECGREGSELPPSGEETPGRRKSPSQSCKKGGES 402
           S R           +D P      +R      S+LPP        +  PS+  +    S
Sbjct: 436 SIRN--------GFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRS 486


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 115/419 (27%), Positives = 145/419 (34%), Gaps = 90/419 (21%)

Query: 33  PTLRHSAS------ALRPPRLSRG------KDLKPRCGRGPAHSPDPGEGCEAWRRLSAD 80
           P LR +A+        RPP L  G      K   P  G G    P PG       R    
Sbjct: 109 PKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGH------RSGPP 162

Query: 81  RWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACAR 140
              R     PR  + S P   P P      PRP+      P  R G    PG P      
Sbjct: 163 EPQRNRMPPPRPDVGSKPDSIPPPVPST--PRPIQS---SPHNR-GSPPVPGGP------ 210

Query: 141 AKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATP-------GPQKGRGSAER--- 190
               R  +P P  PP P     A+  G   + P +S++P        P   R   ++   
Sbjct: 211 ----RQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPP 266

Query: 191 ----TNHIPKDKQRVAAPPPPER-----PRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTR 241
                 + P   +    PPPP+      P  P    SS    P PP    G         
Sbjct: 267 PPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPG-------PP 319

Query: 242 PLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRN------PSPRPAPACGEL--RL 293
           PLP +SS   E P       + SS + PLP   SP R+      PS RP P   +   R 
Sbjct: 320 PLPPSSSGNDETPRLPQRNLSLSSSTPPLP---SPGRSGPLPPPPSERPPPPVRDPPGRS 376

Query: 294 GRLSPPR-ADTGGSSSGGC---------SGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAE 343
           G L PP      GS+S            SG DS  R+ P PP P   P+AGAP  P P+ 
Sbjct: 377 GPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSP-RSGPRPPLPPDRPSAGAPPPPPPST 435

Query: 344 SRRGPGPAQGPPSRRDEPRRVVIAARECGREGSELPPSGEETPGRRKSPSQSCKKGGES 402
           S R           +D P      +R      S+LPP        +  PS+  +    S
Sbjct: 436 SIRN--------GFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRS 486


>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
          Length = 1120

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 92/356 (25%), Positives = 123/356 (34%), Gaps = 53/356 (14%)

Query: 25  RLAEALSQPTLRHSASALRPPRLSRGKDLKP----RCGRGPAHSPD---PGEGCEAWRRL 77
           RLAE L +  L+  A +    RL++G +L        G GPA +       +G E    L
Sbjct: 536 RLAE-LRRGLLQGEALSEGGRRLAKGPELMAIEGLENGEGPATAGPRLLTFQGSELSPEL 594

Query: 78  SA-------DRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQA 130
            A       +  P P + SP      A  +    +++   P+P  G   PP+ R  L + 
Sbjct: 595 QAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQER-NLPEG 653

Query: 131 PGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAER 190
             RP   C+   G       PP      P           +G  +S  PGP  G   A  
Sbjct: 654 TERPPKLCSSLPG-----QGPPPYVFMYP-----------QGSPSSPAPGPPPGAPWAFS 697

Query: 191 TNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEH---------AGGRRKKFTRTR 241
               P      A PP P RP+    R S  LS P P E           G     +    
Sbjct: 698 YLAGPP-----ATPPDPPRPK----RRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLT 748

Query: 242 PLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRA 301
             P  S+ +   PS  P  A  +  S       +  + P P P      +      PP  
Sbjct: 749 RRPGRSALVRTSPSVTPTPARGTPRSQSFALR-ARRKGPPPPPPKRLSSVSGPSPEPPPL 807

Query: 302 DTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSR 357
           D       G +GP  + RTL  P  P+  P   AP  P        PGP   PPSR
Sbjct: 808 DESPGPKEGATGP--RRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSR 861



 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 74/328 (22%), Positives = 105/328 (32%), Gaps = 57/328 (17%)

Query: 61   PAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP 120
            P+ +P P  G    +  +     +     P   L+S  G  P+P    + P P  G   P
Sbjct: 761  PSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGP 820

Query: 121  PRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPG 180
             R  +     P  P              P PP P  P   +     G     P+  ++  
Sbjct: 821  RRRTLSEPAGPSEP--------------PGPPAPAGPASDTEEEEPGPEGTPPSRGSS-- 864

Query: 181  PQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRT 240
              +G   AE  N   K + + A PPP E P  P      GL           RR K    
Sbjct: 865  -GEGLPFAEEGNLTIKQRPKPAGPPPRETPVPP------GLDFNLTESDTVKRRPKCRER 917

Query: 241  RPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPR 300
             PL +T+     V S  P        +APLP       +P+P  +P    L       P+
Sbjct: 918  EPL-QTALLAFGVASATP------GPAAPLP-------SPTPGESPPASSL-------PQ 956

Query: 301  ADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESR--------RGPGPAQ 352
             +     + G   P       P+P      P    PG  + A SR          P    
Sbjct: 957  PEPSSLPAQGVPTP-----LAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAALL 1011

Query: 353  GPPSRRDEPRRVVIAARECGREGSELPP 380
              P     P+ V +A  +    G +L P
Sbjct: 1012 KVPGAGTAPKPVSVACTQLAFSGPKLAP 1039



 Score = 30.0 bits (66), Expect = 4.0
 Identities = 43/137 (31%), Positives = 48/137 (35%), Gaps = 32/137 (23%)

Query: 24   PRLAEALSQPTLRHS--ASALRPPRLSR------GKDLKPRCGRGPAHSPDPGEGCEAWR 75
            P  A  L  PT   S  AS+L  P  S          L P     P   P PG G E+  
Sbjct: 934  PGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLES-- 991

Query: 76   RLSADRW-------PRPASLSPRAALASAPGQKPQPARQAQL------------PRPVSG 116
              +A RW         PA+L       +AP  KP      QL            PRPV  
Sbjct: 992  -SAASRWNGETEPPAAPAALLKVPGAGTAP--KPVSVACTQLAFSGPKLAPRLGPRPVPP 1048

Query: 117  VRPPPRGRVGLSQAPGR 133
             RP   G VG  QA  R
Sbjct: 1049 PRPESTGTVGPGQAQQR 1065


>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
          Length = 1202

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 92/356 (25%), Positives = 123/356 (34%), Gaps = 53/356 (14%)

Query: 25  RLAEALSQPTLRHSASALRPPRLSRGKDLKP----RCGRGPAHSPD---PGEGCEAWRRL 77
           RLAE L +  L+  A +    RL++G +L        G GPA +       +G E    L
Sbjct: 618 RLAE-LRRGLLQGEALSEGGRRLAKGPELMAIEGLENGEGPATAGPRLLTFQGSELSPEL 676

Query: 78  SA-------DRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQA 130
            A       +  P P + SP      A  +    +++   P+P  G   PP+ R  L + 
Sbjct: 677 QAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQER-NLPEG 735

Query: 131 PGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAER 190
             RP   C+   G       PP      P           +G  +S  PGP  G   A  
Sbjct: 736 TERPPKLCSSLPG-----QGPPPYVFMYP-----------QGSPSSPAPGPPPGAPWAFS 779

Query: 191 TNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEH---------AGGRRKKFTRTR 241
               P      A PP P RP+    R S  LS P P E           G     +    
Sbjct: 780 YLAGPP-----ATPPDPPRPK----RRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLT 830

Query: 242 PLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRA 301
             P  S+ +   PS  P  A  +  S       +  + P P P      +      PP  
Sbjct: 831 RRPGRSALVRTSPSVTPTPARGTPRSQSFALR-ARRKGPPPPPPKRLSSVSGPSPEPPPL 889

Query: 302 DTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSR 357
           D       G +GP  + RTL  P  P+  P   AP  P        PGP   PPSR
Sbjct: 890 DESPGPKEGATGP--RRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSR 943



 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 74/328 (22%), Positives = 105/328 (32%), Gaps = 57/328 (17%)

Query: 61   PAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP 120
            P+ +P P  G    +  +     +     P   L+S  G  P+P    + P P  G   P
Sbjct: 843  PSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGP 902

Query: 121  PRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPG 180
             R  +     P  P              P PP P  P   +     G     P+  ++  
Sbjct: 903  RRRTLSEPAGPSEP--------------PGPPAPAGPASDTEEEEPGPEGTPPSRGSS-- 946

Query: 181  PQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRT 240
              +G   AE  N   K + + A PPP E P  P      GL           RR K    
Sbjct: 947  -GEGLPFAEEGNLTIKQRPKPAGPPPRETPVPP------GLDFNLTESDTVKRRPKCRER 999

Query: 241  RPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPR 300
             PL +T+     V S  P        +APLP       +P+P  +P    L       P+
Sbjct: 1000 EPL-QTALLAFGVASATP------GPAAPLP-------SPTPGESPPASSL-------PQ 1038

Query: 301  ADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESR--------RGPGPAQ 352
             +     + G   P       P+P      P    PG  + A SR          P    
Sbjct: 1039 PEPSSLPAQGVPTP-----LAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAALL 1093

Query: 353  GPPSRRDEPRRVVIAARECGREGSELPP 380
              P     P+ V +A  +    G +L P
Sbjct: 1094 KVPGAGTAPKPVSVACTQLAFSGPKLAP 1121



 Score = 30.0 bits (66), Expect = 4.0
 Identities = 43/137 (31%), Positives = 48/137 (35%), Gaps = 32/137 (23%)

Query: 24   PRLAEALSQPTLRHS--ASALRPPRLSR------GKDLKPRCGRGPAHSPDPGEGCEAWR 75
            P  A  L  PT   S  AS+L  P  S          L P     P   P PG G E+  
Sbjct: 1016 PGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLES-- 1073

Query: 76   RLSADRW-------PRPASLSPRAALASAPGQKPQPARQAQL------------PRPVSG 116
              +A RW         PA+L       +AP  KP      QL            PRPV  
Sbjct: 1074 -SAASRWNGETEPPAAPAALLKVPGAGTAP--KPVSVACTQLAFSGPKLAPRLGPRPVPP 1130

Query: 117  VRPPPRGRVGLSQAPGR 133
             RP   G VG  QA  R
Sbjct: 1131 PRPESTGTVGPGQAQQR 1147


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 114/429 (26%), Positives = 144/429 (33%), Gaps = 92/429 (21%)

Query: 11  SEEGRPTTESRIRPRLAEALSQPTLRHSASALRPPRLSRG-KDLKPRCG---RGPAHSPD 66
           S   R    +R  PR     SQP  +    ALRPP+++   KD  P  G     P  +P 
Sbjct: 241 SSPARSGPSARGTPRAPAHPSQPKPK-GLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 299

Query: 67  PGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSG--VRPPPRGR 124
           P          S    P P +  P  A  S  G     A  + LP P       PPP+  
Sbjct: 300 PSAPPSPSAPPSLQTLPSPPATPPSQATTSL-GSPTLQATHSFLPSPPLSPLATPPPQAP 358

Query: 125 VGLS----QAPGRPLGA------------CARAKGIRLVN------PSPP-----RPPEP 157
             L+    QAP  P  +               A  + L+       PSPP      PP  
Sbjct: 359 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 418

Query: 158 IPASAAVTSGLTA----RGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPP------PP 207
            P S + T    A      P     P P      +      P+    +AAPP      PP
Sbjct: 419 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 478

Query: 208 ERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHS 267
           + P  P        ++P+PP    G+   F+ +  LP  S   +  P   P+ A      
Sbjct: 479 QAP--PALATPPLQALPSPPASFPGQAP-FSPSASLPM-SPLATPPPQAPPVLAAPLLQV 534

Query: 268 APLP----FFWSPLRNPSPRPAPACGELRL------GRLSPPRA---------DTGGSSS 308
            P P       +P R P+P P  +    RL      G   PP           D  G SS
Sbjct: 535 PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 594

Query: 309 ----------GGCSGPDSKHRTLPAPPA------PTAW------PAA--GAPGAPNPAES 344
                     G  SGP+      P P A      P AW      P A  GAPGAP P   
Sbjct: 595 SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP 654

Query: 345 RRGPGPAQG 353
             GPG A G
Sbjct: 655 ATGPGSADG 663



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 99/385 (25%), Positives = 136/385 (35%), Gaps = 89/385 (23%)

Query: 43  RPPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWR---------RLSADRW---------PR 84
           RPP   RG+   P     P     PG      R         R+SA+           P+
Sbjct: 84  RPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPK 143

Query: 85  PASLSP---RAALASAPGQ-KPQPARQAQ-------LPRPVSGVRPPPRGRVGLSQAPGR 133
            ++LS    R      PG   P  AR+++       LPRP    RP P      ++ P +
Sbjct: 144 RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP-----TEGPRK 198

Query: 134 PLGACARAKGIRLVNPSPPRPPEPI-------PASAAVTSGLTA------RGPNTSATPG 180
            + + +         PSP     P        PAS +++S  T        GP+   TP 
Sbjct: 199 SVSSASEHS---TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP- 254

Query: 181 PQKGRGSAERTNHIPKDKQRVAAPP--PPERPRVPFCR--GSSGLSVPTPPEHAGGRRKK 236
               R  A  +   PK  Q +  P   PP +   P      SS L+ P+P          
Sbjct: 255 ----RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310

Query: 237 FTRTRPLPRTSSFLSEVPSTRPLCATSS--------SHS-APLPFFWSPLRNPSPRPAPA 287
             +T P P         P+T P  AT+S        +HS  P P   SPL  P P+  PA
Sbjct: 311 SLQTLPSP---------PATPPSQATTSLGSPTLQATHSFLPSPPL-SPLATPPPQAPPA 360

Query: 288 CGELRLGRLSPPRADTGGSSSGGCSGPDSKH------RTLPAPPAPTAWPAAGAPGAP-- 339
              L L  L  P +          + P  +         L AP +P   P   AP +P  
Sbjct: 361 ---LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 417

Query: 340 NPAESRRGPGPAQGPPSRRDEPRRV 364
           +P  S     P+Q PPS    P +V
Sbjct: 418 SPPVSPSATPPSQAPPSLAAPPLQV 442



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 90/329 (27%), Positives = 119/329 (36%), Gaps = 42/329 (12%)

Query: 86  ASLSPRAALASAPGQ-KPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGR-PLGACARAKG 143
           A  + R   A APG   P+P      PRP   V P     +G + A GR PL   A   G
Sbjct: 10  AGAAARTPAARAPGLLTPRPPGS---PRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66

Query: 144 IRLVNPSPPRPPEPIPASAAVTSGLTARGP---NTSATPGPQKGRGSAE-RTNHIPKDKQ 199
              +  S PR   P   S    SG   R P   NTS  P    GR S   R   + +   
Sbjct: 67  GATIPESAPRAG-PTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 125

Query: 200 RVAAPPPPERPRVPFCRGSSGLSV--------PTP--PEHAGGRRKKFTRTRP-LPRTSS 248
           R++A     R +       S LS         PTP  P  A  RR +   T   LPR + 
Sbjct: 126 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 185

Query: 249 FLSEVPST---RPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGG 305
                P T   R   +++S HS   P       +P+ R  P+ G    G L  P + +  
Sbjct: 186 SARPRPPTEGPRKSVSSASEHSTTEP-------SPAARRRPSAG----GGLQRPASRSLS 234

Query: 306 SSSGGCSGPDSKHRTLPAPPAPTAWPAAGA-PGAPNPAESRRGPGPAQGPPSRRDEPRRV 364
           SS+   S P        + P+    P A A P  P P   +    P   PP +   P   
Sbjct: 235 SSATPLSSPAR------SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 288

Query: 365 VIAARECGREGSELPPSGEETPGRRKSPS 393
            +++          PPS    P  +  PS
Sbjct: 289 PLSSSPLATPSPSAPPSPSAPPSLQTLPS 317



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 85/303 (28%), Positives = 112/303 (36%), Gaps = 46/303 (15%)

Query: 83  PRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACARAK 142
           PR          AS  G++  PA+    P PVS       GR   +  PG PLG     K
Sbjct: 75  PRAGPTRTSRPPASGRGERAPPAKNTS-PGPVSSP-----GRASGTTRPG-PLGQ----K 123

Query: 143 GIRLVNPSPPRPPEPI--PASAAVTSGLT--ARGPNTSATPGPQKGRGSAERTNHI--PK 196
           G+R+         +    P  +A+++G      GP T  TP P   R S      +  P+
Sbjct: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGP-TPGTPSPAMARRSRAAGTEVGLPR 182

Query: 197 DKQRVAAPPPPERPRVPFCRGSS-GLSVPTP-----PEHAGGRRKKFTRTRPLPRT--SS 248
                   PP E PR      S    + P+P     P   GG ++  +R+     T  SS
Sbjct: 183 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 242

Query: 249 FLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRP-----APACGELRLGRLSPPRADT 303
                PS R      +  S P P     LR P   P     APA G L     S P A  
Sbjct: 243 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS----SSPLATP 298

Query: 304 GGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGA----------PNPAESRRGPGPAQG 353
             S+    S P S  +TLP+PPA     A  + G+          P+P  S     P Q 
Sbjct: 299 SPSAPPSPSAPPSL-QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 357

Query: 354 PPS 356
           PP+
Sbjct: 358 PPA 360



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 83/318 (26%), Positives = 115/318 (36%), Gaps = 69/318 (21%)

Query: 83  PRPASLSPRAALASA---------PGQKPQPARQAQLPRPVSG------------VRPPP 121
           PRP +  PR +++SA         P  + +P+    L RP S              R  P
Sbjct: 189 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 248

Query: 122 RGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPP--EPIPASAAVTSGLTARGPNTSATP 179
             R G  +AP  P  +  + KG++ + P    PP  +  PA   ++S   A  P+ SA P
Sbjct: 249 SAR-GTPRAPAHP--SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT-PSPSAPP 304

Query: 180 GPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLS-----VPTPPEHAGGRR 234
            P             P   Q + +PP     +     GS  L      +P+PP       
Sbjct: 305 SPSA-----------PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP---- 349

Query: 235 KKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRP--APACGELR 292
                  P P+    L+  P   P    S   S PL    SPL  PSP+   A A   L+
Sbjct: 350 ----LATPPPQAPPALALPPLQAP---PSPPASPPL----SPLATPSPQAPNALAVHLLQ 398

Query: 293 LGRLSPPRADTGGSSSGGCSGPDSKHRTLP--APPAPTA-------WPAAGAPGAPNPAE 343
                PP        S   S P S   T P  APP+  A        P A  P +P+   
Sbjct: 399 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 458

Query: 344 SRRGPGPAQGPPSRRDEP 361
             + P P   PP +  +P
Sbjct: 459 PPQAPPPLAAPPLQLAKP 476



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 95/362 (26%), Positives = 126/362 (34%), Gaps = 69/362 (19%)

Query: 16  PTTESRIRPRLAEALSQPTLRHSASALRP-PRLSRGKDLKPRCGRGPAHSPDPG-EGCEA 73
           P+  +R RP     L +P  R  +S+  P    +R         R PAH   P  +G +A
Sbjct: 211 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA 270

Query: 74  WR-------RLSADRWPRPASLSPRAALA-SAPGQKPQPARQAQLPRPVSGVRPPPRGRV 125
            R       R  A     P S SP A  + SAP     P     LP P +   PP +   
Sbjct: 271 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPA--TPPSQATT 328

Query: 126 GL---------SQAPGRPLGACARAKGIRLVNPSPPRPPE-PIPASAAVTSGLTARGPNT 175
            L         S  P  PL          L  P P  PP   +P   A  S   +   + 
Sbjct: 329 SLGSPTLQATHSFLPSPPLSP--------LATPPPQAPPALALPPLQAPPSPPASPPLSP 380

Query: 176 SATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVP--TPPEHAGGR 233
            ATP PQ     A      P       +PPP    + PF   +S    P  TPP  A   
Sbjct: 381 LATPSPQAPNALAVHLLQAP------FSPPPSPPVQAPFSPPASPPVSPSATPPSQAP-- 432

Query: 234 RKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRL 293
                     P  ++   +VP + P     S  + P P      + P P  AP    L+L
Sbjct: 433 ----------PSLAAPPLQVPPSPPASPPMSPSATPPP------QAPPPLAAPP---LQL 473

Query: 294 GRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQG 353
            +  PP+A    ++           + LP+PPA     A  +P A  P      P P Q 
Sbjct: 474 AK-PPPQAPPALATP--------PLQALPSPPASFPGQAPFSPSASLPMSPLATP-PPQA 523

Query: 354 PP 355
           PP
Sbjct: 524 PP 525



 Score = 35.4 bits (80), Expect = 0.096
 Identities = 42/150 (28%), Positives = 55/150 (36%), Gaps = 21/150 (14%)

Query: 261 ATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSP-------PRADTGGSSSGGCSG 313
           A + + +A  P   +P    SPRP P      L  L         P A+  G   GG + 
Sbjct: 12  AAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI-GGATI 70

Query: 314 PDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDEPRRVVIAARECGR 373
           P+S  R   A P  T+ P A   G   P      PGP   P       R         G+
Sbjct: 71  PESAPR---AGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR-----PGPLGQ 122

Query: 374 EGSELPPSGEETPGRRK---SPSQSCKKGG 400
           +G  +  S EET  R K   +P +S    G
Sbjct: 123 KGLRI--SAEETVARGKATEAPKRSALSAG 150


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 92/377 (24%), Positives = 127/377 (33%), Gaps = 68/377 (18%)

Query: 44  PPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLSADRWPRPA---SLSPRAALASAPGQ 100
           PP   + +   P+ G  P   P PG+           + P P    S SPR+      G 
Sbjct: 72  PPPPGKPQGPPPQGGNKPQGPPPPGK----------PQGPPPQGDKSRSPRSPPGKPQGP 121

Query: 101 KPQPARQAQLPRPVSGVR--PPPRG--RVGLSQAPGRPLGACARAKGIRLVNPSPPRPPE 156
            PQ   Q Q P P  G    PPP+G  +      PG+P G   +       + SPP  P+
Sbjct: 122 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQ 181

Query: 157 PIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCR 216
             P       G   +GP     P P K +G   +  + P+       PPPP +P+ P  +
Sbjct: 182 GPPPQG----GNQPQGP----PPPPGKPQGPPPQGGNKPQ------GPPPPGKPQGPPPQ 227

Query: 217 GSS-GLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWS 275
           G +   S  +PP    G         P P+  +   + P   P          P P   +
Sbjct: 228 GDNKSQSARSPPGKPQG---------PPPQGGN-QPQGPPPPP-----GKPQGPPPQGGN 272

Query: 276 PLRNPSPR-----PAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAW 330
             + P P      P P  G       SPP    G    GG             PP P   
Sbjct: 273 KPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGG--------NQPQGPPPPPGK 324

Query: 331 PAAGAPGAPNPAESRRGPGPAQGPP--------SRRDEPRRVVIAARECGREGSELPPSG 382
           P    P   N  +    PG  QGPP        S R  P +     ++ G      PP  
Sbjct: 325 PQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPA 384

Query: 383 EETPGRRKSPSQSCKKG 399
              P + ++P     +G
Sbjct: 385 GGNPQQPQAPPAGQPQG 401



 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 79/321 (24%), Positives = 108/321 (33%), Gaps = 56/321 (17%)

Query: 89  SPRAALASAPGQKPQPARQAQLPRPVSGVR--PPPRGR---VGLSQAPGRPLGACARAKG 143
           SP     +  G  PQ   + Q P    G    PPP+G     G    PG+P G   +  G
Sbjct: 28  SPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG-G 86

Query: 144 IRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAA 203
            +   P PP  P+  P       G  +R P +     P K +G   +  + P+       
Sbjct: 87  NKPQGPPPPGKPQGPPPQ-----GDKSRSPRSP----PGKPQGPPPQGGNQPQ-----GP 132

Query: 204 PPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATS 263
           PPPP +P+ P  +G +    P PP    G         P     S  S  P  +P     
Sbjct: 133 PPPPGKPQGPPPQGGNKPQGPPPPGKPQG-------PPPQGDNKSRSSRSPPGKP----- 180

Query: 264 SSHSAPLPFFWSPLRNPSPRPAPACGELRLG-------------RLSPPRADTGGSSS-- 308
                P P   +  + P P P    G    G             +  PP+ D    S+  
Sbjct: 181 ---QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARS 237

Query: 309 --GGCSGPDSKHRTLP-APPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDEPRRVV 365
             G   GP  +    P  PP P   P    P   N  +    PG  QGPP +     R  
Sbjct: 238 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSR-- 295

Query: 366 IAARECGREGSELPPSGEETP 386
            ++R    +    PP G   P
Sbjct: 296 -SSRSPPGKPQGPPPQGGNQP 315



 Score = 36.2 bits (82), Expect = 0.056
 Identities = 32/117 (27%), Positives = 39/117 (33%), Gaps = 12/117 (10%)

Query: 279 NPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGA 338
           NP   P P  G    G  SPP    G    GG             PP P   P    P  
Sbjct: 35  NPQGAP-PQGGNKPQGPPSPPGKPQGPPPQGG--------NQPQGPPPPPGKPQGPPPQG 85

Query: 339 PNPAESRRGPGPAQGPPSRRDE---PRRVVIAARECGREGSELPPSGEETPGRRKSP 392
            N  +    PG  QGPP + D+   PR      +    +G   P      PG+ + P
Sbjct: 86  GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 142


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 62.4 bits (150), Expect = 7e-10
 Identities = 83/322 (25%), Positives = 114/322 (35%), Gaps = 52/322 (16%)

Query: 44  PPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLSADRWPRPA---SLSPRAALASAPGQ 100
           PP   + +   P+ G  P   P PG+           + P P    S SPR+      G 
Sbjct: 51  PPPPGKPQGPPPQGGNKPQGPPPPGK----------PQGPPPQGDKSRSPRSPPGKPQGP 100

Query: 101 KPQPARQAQLPRPVSGVR--PPPRG--RVGLSQAPGRPLGACARAKGIRLVNPSPPRPPE 156
            PQ   Q Q P P  G    PPP+G  R      PG+P G   +    R     P +P  
Sbjct: 101 PPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG 160

Query: 157 PIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCR 216
           P P       G   +GP     P P K +G        P+  ++   PPPP +P+ P  +
Sbjct: 161 PPPQG-----GNQPQGP----PPPPGKPQGPP------PQGGKKPQGPPPPGKPQGPPPQ 205

Query: 217 GSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSP 276
           G    S  +PP    G         P P+  +   + P   P          P P   + 
Sbjct: 206 GDKSRSSQSPPGKPQG---------PPPQGGN-QPQGPPPPP-----GKPQGPPPQGGNK 250

Query: 277 LRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAP 336
            + P P   P     + G     ++ +  S  G   GP  +    P  P P A      P
Sbjct: 251 PQGPPPPGKPQGPPAQGGS----KSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP 306

Query: 337 GAPNPAESRRGPGPAQ-GPPSR 357
            AP   + +  P P Q G PSR
Sbjct: 307 QAPPAGQPQGPPRPPQGGRPSR 328



 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 81/327 (24%), Positives = 110/327 (33%), Gaps = 54/327 (16%)

Query: 89  SPRAALASAPGQKPQPARQAQLPRPVSGVR--PPPRG--RVGLSQAPGRPLGACARAKGI 144
           SP     +  G  PQ   + Q P P  G    PPP+G  +      PG+P G   +    
Sbjct: 28  SPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKS 87

Query: 145 RLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAP 204
           R     P +P  P P       G   +GP     P P K +G        P+   R   P
Sbjct: 88  RSPRSPPGKPQGPPPQG-----GNQPQGP----PPPPGKPQGPP------PQGGNRPQGP 132

Query: 205 PPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSS 264
           PPP +P+ P  +G    S  +PP    G         P P+  +   + P   P      
Sbjct: 133 PPPGKPQGPPPQGDKSRSPRSPPGKPQG---------PPPQGGN-QPQGPPPPP-----G 177

Query: 265 SHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSS---GGCSGPDSKHRTL 321
               P P      + P P   P        +  PP+ D   SS    G   GP  +    
Sbjct: 178 KPQGPPPQGGKKPQGPPPPGKP--------QGPPPQGDKSRSSQSPPGKPQGPPPQGGNQ 229

Query: 322 P-APPAPTAWPAAGAPGAPNPAESRRGPGPAQGPP--------SRRDEPRRVVIAARECG 372
           P  PP P   P    P   N  +    PG  QGPP        S R  P +     ++ G
Sbjct: 230 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEG 289

Query: 373 REGSELPPSGEETPGRRKSPSQSCKKG 399
                 PP     P + ++P     +G
Sbjct: 290 NNPQGPPPPAGGNPQQPQAPPAGQPQG 316


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 75/313 (23%), Positives = 112/313 (35%), Gaps = 27/313 (8%)

Query: 33  PTLRHSASALRPPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLSADRWPRPASLSPRA 92
           P +R  A+A  P   +RGK+  P     P+     G       R    R  R  S S  +
Sbjct: 343 PRVRDKAAAAAPTPPARGKE-SPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSAS 401

Query: 93  ALASAPGQKPQPARQAQLPRPVSGVRPPP-----RGRVGLSQAPGRPLGACARAKGIRLV 147
           A      ++P+PA      R +S  R        RG  G    PG   G     K  +  
Sbjct: 402 APRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAK-- 459

Query: 148 NPSPPRPPEPIPASAAVTSGLTAR-----GPNTSATPGPQKGRGSAERTNHIPKDKQRVA 202
                RPP   PAS + + G   R     G ++S +PGP     S+ R+    + +    
Sbjct: 460 ----ERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEK 515

Query: 203 APPPPER---PRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPL 259
            P  P R   P+ P  R   G       E    R ++  R+R          + PS    
Sbjct: 516 RPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARR--RSRSYSPIRKRRRDSPSFMEP 573

Query: 260 CATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHR 319
              +S+   P+P++      PSP  + +C        S  R+ + G S G  S      R
Sbjct: 574 RRITSARKRPIPYY-----RPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTR 628

Query: 320 TLPAPPAPTAWPA 332
           +    P+ T  P+
Sbjct: 629 SRTRSPSRTPSPS 641



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 74/292 (25%), Positives = 106/292 (36%), Gaps = 58/292 (19%)

Query: 150 SPPRPPEPIPASAAVTSGLTARGPNTSATPG---PQKGRGSAERTN---------HIP-- 195
           SP    E     +  +SG  +R P+ S   G   PQ+  GS +R+          H P  
Sbjct: 279 SPKHRDEGRKTGSQRSSG--SRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPPD 336

Query: 196 ---------KDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAG------GRRKKFTRT 240
                    +DK   AAP PP R +       S  S P+     G      GRR++  R 
Sbjct: 337 KPSSPSPRVRDKAAAAAPTPPARGK----ESPSPRSAPSSQGRGGRAAGGAGRRRRRRRR 392

Query: 241 RPLPRTSSFLSEV-----PSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELR--- 292
           R   R+S+          P   P   +S S S       S     +P P P  G  R   
Sbjct: 393 RRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHG 452

Query: 293 ----LGRLSPPRADTGGSSS-----GGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAE 343
                 +  PPRA    +S      G   GP+ K  +    P P +W ++ +P       
Sbjct: 453 GHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRS 512

Query: 344 SRRGPGPAQGPPSRRDEPRRVVIAARECGREGSELPPSGEETPGRRKSPSQS 395
           + + P      PSR   P++ +  +R+   EG       E T  RR+S S S
Sbjct: 513 AEKRP----HSPSRSPSPKKPL--SRDKDGEGRARHSEAEATRARRRSRSYS 558



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 62/254 (24%), Positives = 91/254 (35%), Gaps = 42/254 (16%)

Query: 187 SAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRT 246
           S  R +   +D+ R          R P   G SG      P+  GG  ++       P +
Sbjct: 274 SPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWG---SPQRNGGSGQRSGAHGGRPGS 330

Query: 247 SSFLSEVPST-RPLCATSSSHSAPLPFFWSPLR---NPSPRPAPACGELRLGRLSPP--- 299
           +    + PS+  P     ++ +AP P    P R   +PSPR AP+  + R GR +     
Sbjct: 331 AHSPPDKPSSPSPRVRDKAAAAAPTP----PARGKESPSPRSAPS-SQGRGGRAAGGAGR 385

Query: 300 -----RADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGP 354
                R      SS        + R  PAPP  ++   + A  + +    R  PGP   P
Sbjct: 386 RRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEP 445

Query: 355 PSRR----------DEPRRVVIAARE-----CGREGSELPPSGEETPG-------RRKSP 392
            S R          + P R   A+        GR G     S   +PG         +SP
Sbjct: 446 GSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSP 505

Query: 393 SQSCKKGGESILHS 406
           S+S  +  E   HS
Sbjct: 506 SKSRSRSAEKRPHS 519



 Score = 37.4 bits (85), Expect = 0.025
 Identities = 43/150 (28%), Positives = 57/150 (38%), Gaps = 33/150 (22%)

Query: 233 RRKKFTRTRPLPRTSSFLSEVPSTRPLCATS-SSHSAPLPFFWSPLRNPS---PR----- 283
           +RK+  + +  P T S     P  R    +S SSHS  L   +S  R+PS   P+     
Sbjct: 232 KRKEKNKEKKRPHTES-----PGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEG 286

Query: 284 -------------PAPACGELRLGRLSPPRADTGGSSSGGCSG-PDSKHRT--LPAPPAP 327
                        P+P+ G    G  SP R    G  SG   G P S H     P+ P+P
Sbjct: 287 RKTGSQRSSGSRSPSPSGGS---GWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSP 343

Query: 328 TAWPAAGAPGAPNPAESRRGPGPAQGPPSR 357
                A A     PA  +  P P   P S+
Sbjct: 344 RVRDKAAAAAPTPPARGKESPSPRSAPSSQ 373


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 91/318 (28%), Positives = 109/318 (34%), Gaps = 53/318 (16%)

Query: 63   HSPDPGEGCEAWRRLSADRWPRPA--SLSPRAALASA----PGQKPQPARQA--QLPRPV 114
            H   P    E   RL     P PA   L  RA L S     P   P   R    +LP   
Sbjct: 1393 HHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTA 1452

Query: 115  SGVRP--------PPRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTS 166
             GV P        PP    G+S    +P  + A  +  RL  P   R  E     A VTS
Sbjct: 1453 PGVGPLLLQLGTEPPAPHPGVS----KPWRSAAPEEPERL--PLHVRFLENCQPRAPVTS 1506

Query: 167  GLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTP 226
            G   RGP +   PG             +P    R + PP P  PR     G   L +P P
Sbjct: 1507 G---RGPPSEDGPG-------------VPPPSPRRSVPPSPTSPRASEENGLPLLVLPPP 1550

Query: 227  PEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAP 286
                     +F    PLP    F +              H  PLP   +P     P P P
Sbjct: 1551 APSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPH--PLPDTPAPATPLPPVPPP 1608

Query: 287  ACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLP----APPAPTAWPAAGAPGAPNPA 342
            A         +PP  D+  SS    +  DS+  TL     A P     P   AP AP PA
Sbjct: 1609 AVAA------APPTLDSTASS---LTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPA 1659

Query: 343  ESRRGPGPAQGPPSRRDE 360
              + GP P  G  S  +E
Sbjct: 1660 APQPGPDPPPGTDSGIEE 1677



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 70/293 (23%), Positives = 105/293 (35%), Gaps = 37/293 (12%)

Query: 120  PPRGRVGLSQ---APGRPLGACARAKGIRLVNPSP-PRPPEPIPASAAVTSGLTARGPNT 175
            PP    G S     P   LG     +G R   PSP P  P P    +A   G +++GP  
Sbjct: 1023 PPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPAL 1082

Query: 176  SATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRK 235
                 P +   +A    ++P    R    P  ++ +V              P+  GG   
Sbjct: 1083 RYFQLPPRAASAAM---YVPARSGRGRKGPLVKQTKVE-----------GEPQKGGG--- 1125

Query: 236  KFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGR 295
                  P P  +S  S  P    + A S  +S P+P     ++ PS   +    +     
Sbjct: 1126 ----LPPAPSPTSPASPQPPPA-VAAPSEKNSIPIPTII--IKAPSTSSSGRSSQGSSTE 1178

Query: 296  LSPP-RADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGP 354
              PP + +  G   GG S P       P PP+P+  P   +P  P   +     G A   
Sbjct: 1179 AEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVG 1238

Query: 355  PSRRD-----EPRR--VVIAARECGRE-GSELPPSGEETPGRRKSPSQSCKKG 399
             +RR+     E RR   +  + + G E G +        PG R   S+S  +G
Sbjct: 1239 AARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEG 1291



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 55/213 (25%), Positives = 78/213 (36%), Gaps = 37/213 (17%)

Query: 44   PPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLS-----ADRWP--RPASLSPRAALA- 95
            PPRL+ G     R  RG   SP PG    +    +     + + P  R   L PRAA A 
Sbjct: 1036 PPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAA 1095

Query: 96   ------SAPGQKPQPARQAQL---PRPVSGVRPPPRGRVGLSQAPGRPLGACARAKGIRL 146
                  S  G+K    +Q ++   P+   G+ P P      S  P   + A +    I  
Sbjct: 1096 MYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSI-- 1153

Query: 147  VNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQ-KGRGSAERTNHIPKDKQRVAAPP 205
                 P P   I A +  +SG +++G +T A P  Q +  G        P     ++  P
Sbjct: 1154 -----PIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVP 1208

Query: 206  PPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFT 238
            P   P            VPTP   +G     FT
Sbjct: 1209 PSPSP------------VPTPASPSGPATLDFT 1229



 Score = 37.4 bits (85), Expect = 0.025
 Identities = 62/249 (24%), Positives = 76/249 (30%), Gaps = 53/249 (21%)

Query: 120  PPRGRV----GLSQAPGRPLGACARAKGIRLVNPS--------PPRPPEPIPASAAVTSG 167
            PPR  V    G +  P  PLG    A+   L   S        PPRPP P          
Sbjct: 1334 PPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRPPSP---------- 1383

Query: 168  LTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPP 227
                       P P     S    +H P  +   A+PP P R  + +  G        P 
Sbjct: 1384 -------RYEAPPPTPHHHSPH-AHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPA 1435

Query: 228  EHAGGRRKKFTRTRPL-----PRTSSFLSEVPSTRPLCATSSSHSAP-----LPFFWSPL 277
                 RR    R  P      P      +E P+  P  +     +AP     LP     L
Sbjct: 1436 SPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFL 1495

Query: 278  RNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAP- 336
             N  PR     G        PP  D       G   P  +    P+P +P A    G P 
Sbjct: 1496 ENCQPRAPVTSGR------GPPSED-----GPGVPPPSPRRSVPPSPTSPRASEENGLPL 1544

Query: 337  -GAPNPAES 344
               P PA S
Sbjct: 1545 LVLPPPAPS 1553



 Score = 37.0 bits (84), Expect = 0.033
 Identities = 57/251 (22%), Positives = 73/251 (29%), Gaps = 46/251 (18%)

Query: 149  PSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPE 208
            P PP    P+P+S+               TP P+ G  +      +P         P P 
Sbjct: 929  PEPPYSTPPVPSSSG------------RLTPSPRGGPFNPGSGGPLPASSPASFDGPSPP 976

Query: 209  RPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSA 268
              RV     S   S P PP H            P P+     +  P    +    S    
Sbjct: 977  DTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPP-PQPHHHHAHPPHPPEMETGGSPDDP 1035

Query: 269  PLPFFWSP------LRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLP 322
            P      P       R   P P P       G  SP    + G   G   GP  ++  LP
Sbjct: 1036 PPRLALGPQPSLRGWRGGGPSPTP-------GAPSPSHHGSAGGGGGSSQGPALRYFQLP 1088

Query: 323  APPAPTAWPAAGAPGAPNPAESRRG-PGPAQGPPSRRDEPRRVVIAARECGREGSELPPS 381
                    P A +     PA S RG  GP         EP++           G  LPP+
Sbjct: 1089 --------PRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQK-----------GGGLPPA 1129

Query: 382  GEETPGRRKSP 392
               T      P
Sbjct: 1130 PSPTSPASPQP 1140



 Score = 32.3 bits (72), Expect = 0.81
 Identities = 50/194 (25%), Positives = 61/194 (31%), Gaps = 22/194 (11%)

Query: 179  PGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFT 238
            P    G   A R   + +  +   AP PP RP  P          PTP  H+        
Sbjct: 1349 PASPLGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPP----PTPHHHS-----PHA 1399

Query: 239  RTRPLPRTSSFLSEVPSTRP------LCATSSSHSAPLPFFWSPLRNPSPRPAPACGELR 292
               P+ R        P+ R       L +   S  A  P     L +  P  AP  G L 
Sbjct: 1400 HHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLL 1459

Query: 293  LG-RLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPA 351
            L     PP    G S     + P+   R     P    +     P A  P  S RGP   
Sbjct: 1460 LQLGTEPPAPHPGVSKPWRSAAPEEPERL----PLHVRFLENCQPRA--PVTSGRGPPSE 1513

Query: 352  QGPPSRRDEPRRVV 365
             GP      PRR V
Sbjct: 1514 DGPGVPPPSPRRSV 1527



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 39/149 (26%), Positives = 51/149 (34%), Gaps = 20/149 (13%)

Query: 205  PPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTS-----SFLSEVPSTRPL 259
            P P  P +P   G S  +   P   +       T TR L           L   PS  P 
Sbjct: 1945 PKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGVEFEMRPPLLRRAPS--PS 2002

Query: 260  CATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHR 319
               +S H            +P+PRP+ +   L  G L P   D  GS +GG  G      
Sbjct: 2003 LLPASEHKV----------SPAPRPS-SLPILPSGPLYPGLFDIRGSPTGGAGGSADPFA 2051

Query: 320  TLPAPPAPTAWPAAGAPGAPNPAESRRGP 348
             +  PP P    + G  GA + A     P
Sbjct: 2052 PVFVPPHPGI--SGGLGGALSGASRSLSP 2078



 Score = 30.0 bits (66), Expect = 4.0
 Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 2/60 (3%)

Query: 305 GSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQG--PPSRRDEPR 362
           G++S G  GP S  +    P APT   ++G   + +     R   P++G  P   + +PR
Sbjct: 455 GAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPR 514



 Score = 29.6 bits (65), Expect = 5.2
 Identities = 28/100 (28%), Positives = 39/100 (39%), Gaps = 10/100 (10%)

Query: 96  SAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPP 155
           SAPG     A  +  P P SG +   +     ++     L + +  +G R  +PS  R P
Sbjct: 452 SAPG-----AASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHP 506

Query: 156 EPI---PASAAVTSGLTARGP--NTSATPGPQKGRGSAER 190
           E     P     +SG    GP   T  + GP    GS  R
Sbjct: 507 EDAKRQPRGRPSSSGTPREGPAGGTGGSGGPGGSLGSRGR 546


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 94/364 (25%), Positives = 130/364 (35%), Gaps = 87/364 (23%)

Query: 41  ALRPPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWR---------RLSADRW--------- 82
           A RPP   RG+   P     P     PG      R         R+SA+           
Sbjct: 91  ASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEA 150

Query: 83  PRPASLSP---RAALASAPGQ-KPQPARQAQ-------LPRPVSGVRPPPRGRVGLSQAP 131
           P+ ++LS    R      PG   P  AR+++       LPRP    RP P      ++ P
Sbjct: 151 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP-----TEGP 205

Query: 132 GRPLGACARAKGIRLVNPSPPRPPEPI-------PASAAVTSGLTA------RGPNTSAT 178
            + + + +         PSP     P        PAS +++S  T        GP+   T
Sbjct: 206 RKSVSSASEHS---TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 262

Query: 179 PGPQKGRGSAERTNHIPKDKQRVAAPP--PPERPRVPFC--RGSSGLSVPTPPEHAGGRR 234
           P     R  A  +   PK  Q +  P   PP +   P      SS L+ P+P        
Sbjct: 263 P-----RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP-------- 309

Query: 235 KKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPL--PFFWSPLRNPSPRPAPACGELR 292
                      +++  S+ P T P    SSS +  L  P    PL  PSP   P+   L 
Sbjct: 310 -----------SAALQSQAPPTLPATPHSSSLTCQLATPL---PLAPPSPSAPPSLQTLP 355

Query: 293 LGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPP-APTAWPAAGAPGAPNPAESRRGPGPA 351
               +PP   T   +S G     + H  LP+PP +P A P   AP A      +  P P 
Sbjct: 356 SPPATPPSQAT---TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP 412

Query: 352 QGPP 355
             PP
Sbjct: 413 ASPP 416



 Score = 59.3 bits (142), Expect = 6e-09
 Identities = 102/374 (27%), Positives = 126/374 (33%), Gaps = 88/374 (23%)

Query: 29  ALSQPTLRHSASALRPPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLSADRWPRPASL 88
           +L  PTL+ + S L  P LS            P  +P P +   A         P P + 
Sbjct: 368 SLGSPTLQATHSFLPSPPLS------------PLATPPP-QAPPALALPPLQAPPSPPAS 414

Query: 89  SPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACARAKGIRLVN 148
            P + LA+   Q P       L  P S   PPP   V   QAP  P              
Sbjct: 415 PPLSPLATPSPQAPNALAVHLLQAPFS---PPPSPPV---QAPFSPPA------------ 456

Query: 149 PSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPP--- 205
            SPP  P   P S A  S      P     P P      +      P+    +AAPP   
Sbjct: 457 -SPPVSPSATPPSQAPPS---LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 512

Query: 206 ---PPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCAT 262
              PP+ P  P        ++P+PP    G+   F+ +  LP  S   +  P   P+ A 
Sbjct: 513 AKPPPQAP--PALATPPLQALPSPPASFPGQAP-FSPSASLPM-SPLATPPPQAPPVLAA 568

Query: 263 SSSHSAPLP----FFWSPLRNPSPRPAPACGELRL------GRLSPPRA---------DT 303
                 P P       +P R P+P P  +    RL      G   PP           D 
Sbjct: 569 PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDL 628

Query: 304 GGSSS----------GGCSGPDSKHRTLPAPPA------PTAW------PAA--GAPGAP 339
            G SS          G  SGP+      P P A      P AW      P A  GAPGAP
Sbjct: 629 AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP 688

Query: 340 NPAESRRGPGPAQG 353
            P     GPG A G
Sbjct: 689 LPWPPATGPGSADG 702



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 94/363 (25%), Positives = 128/363 (35%), Gaps = 66/363 (18%)

Query: 11  SEEGRPTTESRIRPRLAEALSQPTLRHSASALRPPRLSRG-KDLKPRCG---RGPAHSPD 66
           S   R    +R  PR     SQP  +    ALRPP+++   KD  P  G     P  +P 
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPK-GLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308

Query: 67  PGEGCEAWRRLSADRWPRPASLSPRAA--LASAPGQKPQPARQAQLPRPVSGVRPPPRGR 124
           P    ++    +    P  +SL+ + A  L  AP     P     LP P +   PP +  
Sbjct: 309 PSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPA--TPPSQAT 366

Query: 125 VGL---------SQAPGRPLGACARAKGIRLVNPSPPRPPE-PIPASAAVTSGLTARGPN 174
             L         S  P  PL          L  P P  PP   +P   A  S   +   +
Sbjct: 367 TSLGSPTLQATHSFLPSPPLSP--------LATPPPQAPPALALPPLQAPPSPPASPPLS 418

Query: 175 TSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVP--TPPEHAGG 232
             ATP PQ     A      P       +PPP    + PF   +S    P  TPP  A  
Sbjct: 419 PLATPSPQAPNALAVHLLQAP------FSPPPSPPVQAPFSPPASPPVSPSATPPSQAP- 471

Query: 233 RRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELR 292
                      P  ++   +VP + P     S  + P P      + P P  AP    L+
Sbjct: 472 -----------PSLAAPPLQVPPSPPASPPMSPSATPPP------QAPPPLAAPP---LQ 511

Query: 293 LGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQ 352
           L +  PP+A    ++           + LP+PPA     A  +P A  P      P P Q
Sbjct: 512 LAK-PPPQAPPALATP--------PLQALPSPPASFPGQAPFSPSASLPMSPLATP-PPQ 561

Query: 353 GPP 355
            PP
Sbjct: 562 APP 564



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 84/319 (26%), Positives = 112/319 (35%), Gaps = 41/319 (12%)

Query: 83  PRPASLSPRAALASAPGQ---KPQPARQAQLPRPVSGVRPPPRGRVGLSQAP-GRPL--G 136
           PRP +  PR +++SA      +P PA + + P    G++ P    +  S  P   P   G
Sbjct: 198 PRPPTEGPRKSVSSASEHSTTEPSPAARRR-PSAGGGLQRPASRSLSSSATPLSSPARSG 256

Query: 137 ACARAKGIRLVNPSPP--------RPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSA 188
             AR       +PS P        RPP+  P        L     +  ATP P     S 
Sbjct: 257 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQ 316

Query: 189 E-----RTNHIPKDKQRVAAPPP--PERPRVPFCRGSSGLSVPTPPEHA----GGRRKKF 237
                  T H      ++A P P  P  P  P    +      TPP  A    G    + 
Sbjct: 317 APPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA 376

Query: 238 TRT-RPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFF---WSPLRNPSPRP--APACGEL 291
           T +  P P  S   +  P   P  A     + P P      SPL  PSP+   A A   L
Sbjct: 377 THSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL 436

Query: 292 RLGRLSPPRADTGGSSSGGCSGPDSKHRTLP--APPAPTA-------WPAAGAPGAPNPA 342
           +     PP        S   S P S   T P  APP+  A        P A  P +P+  
Sbjct: 437 QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 496

Query: 343 ESRRGPGPAQGPPSRRDEP 361
              + P P   PP +  +P
Sbjct: 497 PPPQAPPPLAAPPLQLAKP 515



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 84/351 (23%), Positives = 115/351 (32%), Gaps = 43/351 (12%)

Query: 16  PTTESRIRPRLAEALSQPTLRHSASALRP-PRLSRGKDLKPRCGRGPAHSPDPG-EGCEA 73
           P+  +R RP     L +P  R  +S+  P    +R         R PAH   P  +G +A
Sbjct: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA 279

Query: 74  WRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGR 133
            R       PR  +      L+S+P   P P+   Q   P +           L   P  
Sbjct: 280 LRPPQVTP-PRKDAAPALGPLSSSPLATPSPSAALQSQAPPT-----------LPATPHS 327

Query: 134 PLGACARAKGIRLVNPSPPRPPE----PIPASAAVTSGLTARG-PNTSATPGPQKGRGSA 188
               C  A  + L  PSP  PP     P P +   +   T+ G P   AT         +
Sbjct: 328 SSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS 387

Query: 189 ERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSS 248
                 P+    +A PP    P  P     S L+ P+P   A           P     S
Sbjct: 388 PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP--QAPNALAVHLLQAPFSPPPS 445

Query: 249 FLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSS 308
              + P + P     S  + P      P + P   P+ A   L++    PP        S
Sbjct: 446 PPVQAPFSPPASPPVSPSATP------PSQAP---PSLAAPPLQV----PPSPPASPPMS 492

Query: 309 GGCSGPDSKHRTLPAPPAPTAWPAAGAPGA---------PNPAESRRGPGP 350
              + P      L APP   A P   AP A         P+P  S  G  P
Sbjct: 493 PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 543



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 78/272 (28%), Positives = 98/272 (36%), Gaps = 63/272 (23%)

Query: 136 GACARAKGIR---LVNPSPP---RPPEPI-PASAAVTSGLTARG---------------- 172
           GA AR    R   L+ P PP   RPP P+ PA+  V     A G                
Sbjct: 11  GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70

Query: 173 PNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPER-PRVPFCRGSSGLSVPTPPEHAG 231
           P ++   GP +  G++ R           + PP   R  R P  + +S   V +P     
Sbjct: 71  PESAPRAGPTRSAGTSSR--------NPASRPPASGRGERAPPAKNTSPGPVSSP----- 117

Query: 232 GRRKKFTRTRPLPRTSSFLS-----------EVPSTRPLCA-TSSSHSAPLPFFWSPLRN 279
           GR    TR  PL +    +S           E P    L A      S P P   SP   
Sbjct: 118 GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM- 176

Query: 280 PSPRPAPACGELRLGRLSP---PRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAP 336
            + R   A  E+ L R +P   PR  T G      S   S+H T    PA    P+AG  
Sbjct: 177 -ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA--SEHSTTEPSPAARRRPSAGG- 232

Query: 337 GAPNPA----ESRRGP--GPAQGPPSRRDEPR 362
           G   PA     S   P   PA+  PS R  PR
Sbjct: 233 GLQRPASRSLSSSATPLSSPARSGPSARGTPR 264


>gi|169160903 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 426

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 92/303 (30%), Positives = 111/303 (36%), Gaps = 47/303 (15%)

Query: 117 VRPPPRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPA--SAAVTSGLTARGPN 174
           V P P G    + APG P      A+    + P+P RPP        AA  +G T  G  
Sbjct: 21  VAPQPEG----TDAPG-PAVCSPTARAPPPILPAPQRPPTRAREWEGAAWAAGATGVGAA 75

Query: 175 TSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTP-----PEH 229
             A PG       + R   +P   +  +  P P  PR    RGS G   P P     P  
Sbjct: 76  LLALPG-------SRRLGRVPLTFREASPGPAPGAPRA---RGSCGRE-PGPRRRRAPSS 124

Query: 230 AGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSS-SHSAPLPFFWSPLR-----NPSPR 283
           AG R     R  P PR  S    +P +   C   S   S P        R      P P+
Sbjct: 125 AGKRPAAAARAAP-PRQRSLARCLPRSVGSCVRPSVGPSLPRRHCRRHCRCHCRRRPLPK 183

Query: 284 PAPACGELRLGRLSPPR--ADTGGSSSGGCSG-PDSKHRTLPAPPAPTAWPAAGAPGAPN 340
           P P   + RLG  SPPR  A   GS +   S  P    R     PA          G P 
Sbjct: 184 PPPL--QPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPA--------GHGLPL 233

Query: 341 PAESRRGPGPAQGPPSRRDEPRRVVIAARECGREGSELPPSGEETPGR---RKSPSQSCK 397
           P    RG G   G   RR    R V   R+    GS   P+G   PGR   R++  Q  K
Sbjct: 234 PRSLSRG-GEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRK 292

Query: 398 KGG 400
           +GG
Sbjct: 293 RGG 295



 Score = 36.2 bits (82), Expect = 0.056
 Identities = 69/295 (23%), Positives = 96/295 (32%), Gaps = 74/295 (25%)

Query: 83  PRPASLSPRA--ALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACAR 140
           P PA  +PRA  +    PG + + A  +   RP +  R  P  +  L++   R +G+C R
Sbjct: 97  PGPAPGAPRARGSCGREPGPRRRRAPSSAGKRPAAAARAAPPRQRSLARCLPRSVGSCVR 156

Query: 141 AKGIRLVNPSPPR-----------PPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAE 189
                 V PS PR              P+P    +   L +  P   A P          
Sbjct: 157 PS----VGPSLPRRHCRRHCRCHCRRRPLPKPPPLQPRLGSASPPRLAAP---------- 202

Query: 190 RTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTP------PEHAGGRRKKFTRTRPL 243
                    +  +  P P R R    R  +G  +P P       E  G RR++    R  
Sbjct: 203 -----LAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRRGGEER-- 255

Query: 244 PRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGR-------- 295
                    V   R  CA     S P+P          P      GE R  R        
Sbjct: 256 --------RVRGRRQGCALG---SPPIP--------AGPAAPGRAGERRAARQWRKRGGG 296

Query: 296 --LSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGP 348
             +SP     G    GG + P ++  +    P+P  W      GAP  A    GP
Sbjct: 297 PGVSPREGAQGEGVRGGVT-PRARGSSTCLRPSPATWQG----GAPYRAIFAAGP 346



 Score = 28.9 bits (63), Expect = 9.0
 Identities = 25/78 (32%), Positives = 28/78 (35%), Gaps = 7/78 (8%)

Query: 318 HRTLPAPPAPTAWPAAGAPGAPNPA---ESRRGPGP----AQGPPSRRDEPRRVVIAARE 370
           H   PAP  P   P      AP PA    + R P P     Q PP+R  E      AA  
Sbjct: 10  HPRTPAPGCPEVAPQPEGTDAPGPAVCSPTARAPPPILPAPQRPPTRAREWEGAAWAAGA 69

Query: 371 CGREGSELPPSGEETPGR 388
            G   + L   G    GR
Sbjct: 70  TGVGAALLALPGSRRLGR 87


>gi|48375167 microtubule-associated protein 6 isoform 2 [Homo
           sapiens]
          Length = 439

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 76/290 (26%), Positives = 101/290 (34%), Gaps = 33/290 (11%)

Query: 74  WRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGR 133
           W +L       P   +  +     PG  PQP    Q  +P   + PP    V +   P +
Sbjct: 16  WNQLDKADIAVPLVFTKYSEATEHPGAPPQPPPPQQQAQPA--LAPPSARAVAIETQPAQ 73

Query: 134 -PLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAER-T 191
             L A ARA G     P+P    E  PA+    SG           PGP  G GS     
Sbjct: 74  GELDAVARATG-----PAPGPTGEREPAAGPGRSG-----------PGPGLGSGSTSGPA 117

Query: 192 NHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLS 251
           + + +   R      PE    P CR  S       P     + +K  R  PLPR      
Sbjct: 118 DSVMRQDYRAWKVQRPE----PSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDH-- 171

Query: 252 EVPSTRPLCATSSSHSAPLPFFWSPLRNPSPR---PAPACGELRLGRLSPPRADTGGSSS 308
             P        S++  A  P   +P R P  +   P  A  E R    +P  A  GG ++
Sbjct: 172 --PWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPGGA--GGLAA 227

Query: 309 GGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRR 358
           G  SG D +     A PA     A G      P  + +    A GP + R
Sbjct: 228 GKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGR 277


>gi|48375173 microtubule-associated protein 6 isoform 1 [Homo
           sapiens]
          Length = 813

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 76/290 (26%), Positives = 101/290 (34%), Gaps = 33/290 (11%)

Query: 74  WRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGR 133
           W +L       P   +  +     PG  PQP    Q  +P   + PP    V +   P +
Sbjct: 16  WNQLDKADIAVPLVFTKYSEATEHPGAPPQPPPPQQQAQPA--LAPPSARAVAIETQPAQ 73

Query: 134 -PLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAER-T 191
             L A ARA G     P+P    E  PA+    SG           PGP  G GS     
Sbjct: 74  GELDAVARATG-----PAPGPTGEREPAAGPGRSG-----------PGPGLGSGSTSGPA 117

Query: 192 NHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLS 251
           + + +   R      PE    P CR  S       P     + +K  R  PLPR      
Sbjct: 118 DSVMRQDYRAWKVQRPE----PSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDH-- 171

Query: 252 EVPSTRPLCATSSSHSAPLPFFWSPLRNPSPR---PAPACGELRLGRLSPPRADTGGSSS 308
             P        S++  A  P   +P R P  +   P  A  E R    +P  A  GG ++
Sbjct: 172 --PWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPGGA--GGLAA 227

Query: 309 GGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRR 358
           G  SG D +     A PA     A G      P  + +    A GP + R
Sbjct: 228 GKASGADERDTRRKAGPAWIVRRAEGLGHEQTPLPAAQAQVQATGPEAGR 277


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 86/305 (28%), Positives = 113/305 (37%), Gaps = 46/305 (15%)

Query: 85  PASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACARAKGI 144
           PAS  P    AS  G++  PA+    P PVS       GR   +  PG PLG     KG+
Sbjct: 90  PASRPP----ASGRGERAPPAKNTS-PGPVSSP-----GRASGTTRPG-PLGQ----KGL 134

Query: 145 RLVNPSPPRPPEPI--PASAAVTSGLT--ARGPNTSATPGPQKGRGSAERTNHI--PKDK 198
           R+         +    P  +A+++G      GP T  TP P   R S      +  P+  
Sbjct: 135 RISAEETVARGKATEAPKRSALSAGARRDTSGP-TPGTPSPAMARRSRAAGTEVGLPRPA 193

Query: 199 QRVAAPPPPERPRVPFCRGSS-GLSVPTP-----PEHAGGRRKKFTRTRPLPRT--SSFL 250
                 PP E PR      S    + P+P     P   GG ++  +R+     T  SS  
Sbjct: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253

Query: 251 SEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRP-----APACGELRLGRLSPPRADTGG 305
              PS R      +  S P P     LR P   P     APA G L    L+ P     G
Sbjct: 254 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP--SPSG 311

Query: 306 SSSGGCSGPDSKHRTLPAP---------PAPTAWPAAGAPGAPNPAESRRGPGPAQGPPS 356
           + +     PD+    LPA          P P A P+  AP +     S     P+Q PPS
Sbjct: 312 TKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPS 371

Query: 357 RRDEP 361
               P
Sbjct: 372 MTTPP 376



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 107/404 (26%), Positives = 136/404 (33%), Gaps = 79/404 (19%)

Query: 16  PTTESRIR---PRLAEALSQPTLRHSASALRPPRLSRGKDLKPRCGRGPAHSPDPGEGCE 72
           P T S I    P+   AL+ P L+   S    P  +      P     P  +P       
Sbjct: 581 PETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP 640

Query: 73  AWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLP------RPVSGVRPPPRGRVG 126
               L+      P +L+    L  AP   P P+   Q P       PVS    PP     
Sbjct: 641 PLSPLATPSPQAPNALAVH--LLQAPFSPP-PSPPVQAPFSPPASPPVSPSATPP----- 692

Query: 127 LSQAP----GRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGP-----NTSA 177
            SQAP      PL           ++PS   PP+  P  AA    +    P     + SA
Sbjct: 693 -SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSA 751

Query: 178 TPGPQKGRGSAERTNHIPKDK-----QRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGG 232
           TP P+     A     +P            A PPP+ P  P        ++P+PP    G
Sbjct: 752 TPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAP--PALATPPLQALPSPPASFPG 809

Query: 233 RRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLP----FFWSPLRNPSPRPAPAC 288
           +   F+ +  LP  S   +  P   P+ A       P P       +P R P+P P  + 
Sbjct: 810 QAP-FSPSASLPM-SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 867

Query: 289 GELRL------GRLSPPRA---------DTGGSSS----------GGCSGPDSKHRTLPA 323
              RL      G   PP           D  G SS          G  SGP+      P 
Sbjct: 868 SGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 927

Query: 324 PPA------PTAW------PAA--GAPGAPNPAESRRGPGPAQG 353
           P A      P AW      P A  GAPGAP P     GPG A G
Sbjct: 928 PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 971



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 86/347 (24%), Positives = 127/347 (36%), Gaps = 77/347 (22%)

Query: 41  ALRPPRLSRGKDLKP--RCGRGPAHSPD-------PGEGCEAWRRLSADRW--------- 82
           A RPP   RG+   P      GP  SP        PG   +   R+SA+           
Sbjct: 91  ASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEA 150

Query: 83  PRPASLSP---RAALASAPG-QKPQPARQAQ-------LPRPVSGVRPPPRGRVGLSQAP 131
           P+ ++LS    R      PG   P  AR+++       LPRP    RP P      ++ P
Sbjct: 151 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP-----TEGP 205

Query: 132 GRPLGACARAKGIRLVNPSPPRPPEPI-------PASAAVTSGLT------ARGPNTSAT 178
            + + + +         PSP     P        PAS +++S  T        GP+   T
Sbjct: 206 RKSVSSASEHS---TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 262

Query: 179 PGPQKGRGSAERTNHIPKDKQRVAAP--PPPERPRVPFC--RGSSGLSVPTPPEHAGGRR 234
           P     R  A  +   PK  Q +  P   PP +   P      SS L+ P+P        
Sbjct: 263 P-----RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP-------- 309

Query: 235 KKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLG 294
              T+ RP+P   +  + +P+T P    S   + PL     PL  PSP   P+   L   
Sbjct: 310 -SGTKARPVPPPDNAATPLPATLP---PSPPLATPL-----PLAPPSPSAPPSLQTLPSP 360

Query: 295 RLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNP 341
             +PP       ++     P S  +T+P    P +  +      P+P
Sbjct: 361 PATPPSQAPPSMTTPPMQAPPSL-QTIPPIQVPHSLTSPSLQAPPSP 406



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 109/427 (25%), Positives = 151/427 (35%), Gaps = 87/427 (20%)

Query: 11  SEEGRPTTESRIRPRLAEALSQPTLRHSASALRPPRLSRG-KDLKPRCG---RGPAHSPD 66
           S   R    +R  PR     SQP  +    ALRPP+++   KD  P  G     P  +P 
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPK-GLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308

Query: 67  PGEGCEAWRRLSADR--WPRPASLSPRAALAS----APGQKPQPARQAQLPRPVSGVRPP 120
           P  G +A      D    P PA+L P   LA+    AP     P     LP P +   PP
Sbjct: 309 PS-GTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPA--TPP 365

Query: 121 PRGRVGLSQAPGRPLGACARAKGIR----LVNPSPPRPPEPIPASA--AVTS--GLTARG 172
            +    ++  P +   +      I+    L +PS   PP P+  S+  A TS    T + 
Sbjct: 366 SQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQA 425

Query: 173 PNTSATPGPQKGRGSA---ERTNHIPKDKQRVAAP------PP----------------- 206
            ++  T  P++ + S     R    P D   + AP      PP                 
Sbjct: 426 THSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLT 485

Query: 207 --------------PERPR----VPFCRGSSGLSVP----------TPP-EHAGGRRKKF 237
                         P+ P     +P     S L+ P          TPP E+        
Sbjct: 486 IHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPP 545

Query: 238 TRTRPLPRTSSFLSE--VPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRL-G 294
            +T   P T+  L     P+  PL A  S  + P P   S +  P P+  PA     L G
Sbjct: 546 LQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQG 605

Query: 295 RLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWP-----AAGAPGAPNPAESRRGPG 349
             SPP +    ++    + P      L APP+P A P     A  +P APN         
Sbjct: 606 LPSPPLSPL--ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQA 663

Query: 350 PAQGPPS 356
           P   PPS
Sbjct: 664 PFSPPPS 670



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 88/355 (24%), Positives = 120/355 (33%), Gaps = 50/355 (14%)

Query: 16  PTTESRIRPRLAEALSQPTLRHSASALRP-PRLSRGKDLKPRCGRGPAHSPDPG-EGCEA 73
           P+  +R RP     L +P  R  +S+  P    +R         R PAH   P  +G +A
Sbjct: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA 279

Query: 74  WRRLSADRWPRPASLSPRAALASAPGQKPQPA--RQAQLPRPVSGVRPPPRGRVGLSQAP 131
            R       PR  +      L+S+P   P P+  +   +P P +   P P      +  P
Sbjct: 280 LRPPQVTP-PRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPA-----TLPP 333

Query: 132 GRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERT 191
             PL     A  + L  PSP  PP                 P+  ATP  Q         
Sbjct: 334 SPPL-----ATPLPLAPPSPSAPPS------------LQTLPSPPATPPSQAPPSMTTPP 376

Query: 192 NHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRP-LPRTSSFL 250
              P   Q +   PP +   VP    S  L  P  P      +   +   P L  T SFL
Sbjct: 377 MQAPPSLQTI---PPIQ---VPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFL 430

Query: 251 SEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGG 310
           +  P       TS S  A  P    PL+ P   PA           SPP   +   +   
Sbjct: 431 TMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPA-----------SPPLQTSLSPAVSP 479

Query: 311 CSGPDSKH----RTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDEP 361
            S P + H     +  A  +P A P +     P   +S   P   Q PP+    P
Sbjct: 480 LSSPLTIHPLQALSSLASHSPQA-PLSSLIMPPLETQSSLAPPSLQTPPASLTTP 533



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 78/272 (28%), Positives = 98/272 (36%), Gaps = 63/272 (23%)

Query: 136 GACARAKGIR---LVNPSPP---RPPEPI-PASAAVTSGLTARG---------------- 172
           GA AR    R   L+ P PP   RPP P+ PA+  V     A G                
Sbjct: 11  GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70

Query: 173 PNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPER-PRVPFCRGSSGLSVPTPPEHAG 231
           P ++   GP +  G++ R           + PP   R  R P  + +S   V +P     
Sbjct: 71  PESAPRAGPTRSAGTSSR--------NPASRPPASGRGERAPPAKNTSPGPVSSP----- 117

Query: 232 GRRKKFTRTRPLPRTSSFLS-----------EVPSTRPLCA-TSSSHSAPLPFFWSPLRN 279
           GR    TR  PL +    +S           E P    L A      S P P   SP   
Sbjct: 118 GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM- 176

Query: 280 PSPRPAPACGELRLGRLSP---PRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAP 336
            + R   A  E+ L R +P   PR  T G      S   S+H T    PA    P+AG  
Sbjct: 177 -ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA--SEHSTTEPSPAARRRPSAGG- 232

Query: 337 GAPNPA----ESRRGP--GPAQGPPSRRDEPR 362
           G   PA     S   P   PA+  PS R  PR
Sbjct: 233 GLQRPASRSLSSSATPLSSPARSGPSARGTPR 264


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 89/327 (27%), Positives = 113/327 (34%), Gaps = 60/327 (18%)

Query: 58  GRGPAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGV 117
           G GPA +P  G    A     A R  RP    P+     +P +   PA  A    P + +
Sbjct: 72  GAGPA-APAEGAPGAAPEPPPAGR-ARPGGGGPQRPGPPSPRRPLVPAGPAP---PAAKL 126

Query: 118 RPPPRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSA 177
           RPPP G  G S AP     A A         P+ P  P  + A A    G    GP    
Sbjct: 127 RPPPEGSAG-SCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPG-PGPGPGPGP 184

Query: 178 TPGPQKGRGSAERTNHIPK--DKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRK 235
            PG   G G+A+  N      +    AAP       V          +P P   A G   
Sbjct: 185 GPGKPAGPGAAQTLNGSAALLNSHHAAAPA------VSLVNNGPAALLPLPKPAAPGT-- 236

Query: 236 KFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGR 295
                  + +T  F+       P   +  +  AP     +P   P P PAPA      G 
Sbjct: 237 -------VIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAP---PPPPPAPATLARPPGH 286

Query: 296 ----------LSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAP----GAPNP 341
                     + PP A   G S+G             A PAP   PAAG P    G P P
Sbjct: 287 PAGPPTAAPAVPPPAAAQNGGSAG-------------AAPAPA--PAAGGPAGVSGQPGP 331

Query: 342 AESRRGPGPAQGPPSRRDEPRRVVIAA 368
             +   P P      + + P+RVV AA
Sbjct: 332 GAAAAAPAPG----VKAESPKRVVQAA 354



 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 75/296 (25%), Positives = 94/296 (31%), Gaps = 68/296 (22%)

Query: 86  ASLSPRAALASAPGQKPQP-----ARQA----QLPRPVSGVRP-------PPRGRVGLSQ 129
           A   P A    APG  P+P     AR      Q P P S  RP       PP  +  L  
Sbjct: 71  AGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAK--LRP 128

Query: 130 APGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAE 189
            P    G+CA       V   P    EP PA  A  +G  A        PGP  G G   
Sbjct: 129 PPEGSAGSCAPVPAAAAVAAGP----EPAPAGPAKPAGPAALAARAGPGPGPGPGPGPG- 183

Query: 190 RTNHIPKDKQRVAAPPPPERPRVPFCRGS-SGLSVPTPPEHAGGRRKKFTRTRPLPRTSS 248
                          P P +P  P    + +G +      HA           P      
Sbjct: 184 ---------------PGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPA----- 223

Query: 249 FLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSS 308
             + +P  +P    +   + P     +P       PAPA         SPP A    + +
Sbjct: 224 --ALLPLPKPAAPGTVIQTPPFVGAAAP-------PAPAAP-------SPPAAPAPAAPA 267

Query: 309 GGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRG--------PGPAQGPPS 356
                P     TL  PP   A P   AP  P PA ++ G        P PA G P+
Sbjct: 268 AAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPA 323



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 73/280 (26%), Positives = 88/280 (31%), Gaps = 40/280 (14%)

Query: 85  PASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACARAKGI 144
           P +   RAA A A G           P   +G  P          AP  P    AR  G 
Sbjct: 45  PRTPEVRAAAAGALGNHVVSGS----PAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGG 100

Query: 145 RLVNPSPPRPPEP-IPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAA 203
               P PP P  P +PA  A         P     P P+   GSA     +P      A 
Sbjct: 101 GPQRPGPPSPRRPLVPAGPAP--------PAAKLRPPPE---GSAGSCAPVPAAAAVAAG 149

Query: 204 PPP----PERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPL 259
           P P    P +P  P    +     P P    G          P P   +      +    
Sbjct: 150 PEPAPAGPAKPAGPAALAARAGPGPGPGPGPG--------PGPGPGKPAGPGAAQTLNGS 201

Query: 260 CATSSSHSAPLPFFWSPLRNPS---PRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDS 316
            A  +SH A  P        P+   P P PA     +   +PP        +     P  
Sbjct: 202 AALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQ--TPPFVGAAAPPAPAAPSP-- 257

Query: 317 KHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPS 356
                PA PAP A  AA  P  P PA   R PG   GPP+
Sbjct: 258 -----PAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPT 292



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 80/320 (25%), Positives = 108/320 (33%), Gaps = 49/320 (15%)

Query: 53  LKPRCGRGPAHSPDPGEGCEAWRRL---SADRWPRPASL--SPRAALASAPGQKPQPARQ 107
           L  R G GP   P PG G    +     +A      A+L  S  AA  +       PA  
Sbjct: 166 LAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAAL 225

Query: 108 AQLPRPVSG---VRPPPRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAV 164
             LP+P +    ++ PP        AP  P    A A        + P PP P PA+ A 
Sbjct: 226 LPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPA---APAAAPPPPPPAPATLAR 282

Query: 165 TSGLTARGPNTSA----TPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSG 220
             G  A GP T+A     P   +  GSA             AAP P      P   G +G
Sbjct: 283 PPGHPA-GPPTAAPAVPPPAAAQNGGSAG------------AAPAP-----APAAGGPAG 324

Query: 221 LSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNP 280
           +S    P  A        +     R     +  P+ + L A+  + +A        ++  
Sbjct: 325 VSGQPGPGAAAAAPAPGVKAESPKRVVQ--AAPPAAQTLAASGPASTAASMVIGPTMQGA 382

Query: 281 SPRPAPACGELRLGRLSPPRADTGGSSSGGCSG--PDSKHRTLPAPPA---PTAWPAAGA 335
            P PA          + PP   T      G +G    S  RT  A  +    T  P   A
Sbjct: 383 LPSPA---------AVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLA 433

Query: 336 PGAPNPAESRRGPGPAQGPP 355
           P  P P ++       Q PP
Sbjct: 434 PRLPQPPQNPTNIQNFQLPP 453



 Score = 37.4 bits (85), Expect = 0.025
 Identities = 47/161 (29%), Positives = 57/161 (35%), Gaps = 23/161 (14%)

Query: 251 SEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGG 310
           + V S  P  A  +  +AP     +P   P P PA   G  R G   P R          
Sbjct: 60  NHVVSGSPAGAAGAGPAAPAE--GAPGAAPEPPPA---GRARPGGGGPQRP--------- 105

Query: 311 CSGPDSKHRTL-PAPPAPTAW----PAAGAPG--APNPAESRRGPGPAQGPPSRRDEPRR 363
             GP S  R L PA PAP A     P  G+ G  AP PA +    GP   P         
Sbjct: 106 --GPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGP 163

Query: 364 VVIAARECGREGSELPPSGEETPGRRKSPSQSCKKGGESIL 404
             +AAR     G    P     PG+   P  +    G + L
Sbjct: 164 AALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAAL 204



 Score = 33.9 bits (76), Expect = 0.28
 Identities = 48/171 (28%), Positives = 60/171 (35%), Gaps = 24/171 (14%)

Query: 15  RPTTESRIRPRLAEALSQPTLRH---SASALRPPRLSRGKDLKPRCGRGP---AHSPDPG 68
           RP       P  A A+  P       SA A   P  + G         GP   A +P PG
Sbjct: 282 RPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPG 341

Query: 69  EGCEAWRRLSADRWPRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLS 128
              E+ +R+     P   +L+     ++A      P  Q  LP P +   PPP       
Sbjct: 342 VKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAA--VPPP------- 392

Query: 129 QAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATP 179
            APG P G    A G   V  S  R P       A TSG+ A    T   P
Sbjct: 393 -APGTPTGLPKGAAG--AVTQSLSRTP------TATTSGIRATLTPTVLAP 434



 Score = 31.2 bits (69), Expect = 1.8
 Identities = 30/91 (32%), Positives = 38/91 (41%), Gaps = 10/91 (10%)

Query: 296 LSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGA---PNPAESRR--GPGP 350
           L+P   +   +++G             A  A  A PA GAPGA   P PA   R  G GP
Sbjct: 43  LAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGP 102

Query: 351 AQ-GPPSRRDEPRRVVIAARECGREGSELPP 380
            + GPPS    PRR ++ A          PP
Sbjct: 103 QRPGPPS----PRRPLVPAGPAPPAAKLRPP 129


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 59.3 bits (142), Expect = 6e-09
 Identities = 106/387 (27%), Positives = 123/387 (31%), Gaps = 63/387 (16%)

Query: 33   PTLRHSASALRPPRLSRGKDLKPRC-GRG-PAHSPDPGEGCEAWRRLSADRWPRPASLSP 90
            P L  +A    PP    G  L P   G G P   P PG G      L     P P  L P
Sbjct: 946  PPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL-P 1004

Query: 91   RAALASAPGQKPQPARQAQLPRPVSGVR-PPPRGRVGLSQAPGRPLGACARAKGIRLVNP 149
             A +   P   P P      P P+ G   PPP    G    P  PL           + P
Sbjct: 1005 GAGIPPPP---PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG-------IPP 1054

Query: 150  SPPRPPEPIPASAAVT-SGLTARGPNTSA---TPGPQKGRGSAERTNHIPKDKQRVAAPP 205
             PP P   IP    +  +G+    P   A    P P  G G        P     V  PP
Sbjct: 1055 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-----PPPLPGVGIPP 1109

Query: 206  PPERPR--VPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATS 263
            PP  P   +P      G  +P PP   G          PLPR       +P   PL    
Sbjct: 1110 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAG---IPPPPPLPRVG-----IPPPPPLPGAG 1161

Query: 264  SSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPA 323
                 PLP        P P P P  G      + PP    G    G    P      +P 
Sbjct: 1162 IPPPPPLP----GAGIPPPPPLPGVG------IPPPPPLPG---VGIPPPPPLPGAGIPP 1208

Query: 324  PPAPTAWPAAGAPGAPNPAESRRGPG-------PAQGPPSRRDEPRRVVIAARECGREGS 376
            PP     P  G P AP P     G G       P  GPP         +   + CG    
Sbjct: 1209 PPP---LPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPP 1265

Query: 377  ELPPSG------EETPGRRKSPSQSCK 397
             L PSG       +  G RK P + C+
Sbjct: 1266 PL-PSGLFGLGMNQDKGSRKQPIEPCR 1291



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 67/259 (25%), Positives = 82/259 (31%), Gaps = 35/259 (13%)

Query: 98   PGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEP 157
            P   P P  ++    P  G+ PPP   +     P  P  A  +   ++     PP PP P
Sbjct: 856  PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPP-PPPP 914

Query: 158  IPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERP--RVPFC 215
            +P  A +       G      P P  G G        P      A PPPP  P   +P  
Sbjct: 915  LP-GAGIPPPPPLPGAGILPLP-PLPGAGIPP-----PPPLPGAAIPPPPPLPGAGIPLP 967

Query: 216  RGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWS 275
                G  +P PP   G          PLP        +P   PL         PLP    
Sbjct: 968  PPLPGAGIPPPPPLPGA---GIPPPPPLPGAG-----IPPPPPLPGAGIPPPPPLP---- 1015

Query: 276  PLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGA 335
                P P P P  G      + PP    G   +G    P      +P PP     P AG 
Sbjct: 1016 GAGIPPPPPLPGAG------IPPPPPLPG---AGIPPPPPLPGAGIPPPP---PLPGAGI 1063

Query: 336  PGAPN-PAESRRGPGPAQG 353
            P  P  P      P P  G
Sbjct: 1064 PPPPPLPGAGIPPPPPLPG 1082


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 87/354 (24%), Positives = 118/354 (33%), Gaps = 51/354 (14%)

Query: 29  ALSQPTLRHSASALRPPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLSADRWPR-PAS 87
           AL  PT    A +  PP    G    P  G  P+ +  P +G     +  A   P+ P +
Sbjct: 186 ALQAPTGVTPAPSSAPP----GTPQLPTPGPTPSATAVPPQGSPTASQ--APNQPQAPTA 239

Query: 88  LSPRAALASAPGQKPQPARQAQLPRPVSGVRP--PPRGRVGLSQAPGR---------PLG 136
             P   +  AP   PQ       P   S   P  P  G  G   AP           P G
Sbjct: 240 PVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPG 299

Query: 137 ACARAKGIRLVNPSPPRP----PEPIPASAAVTSGLTARGPNTSAT-PGPQKGRGSAERT 191
             +   G  L +P PP+P    P+     A + +   A  P+TS   P  Q    S +  
Sbjct: 300 PHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP 359

Query: 192 NHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLS 251
              P     +A P     P  P  +  +  +   PP  +G          P P       
Sbjct: 360 REQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPP------- 412

Query: 252 EVPSTRPLCATSSSH---SAPLPFFWSPLRNPSPR-PAPACGELRLGRLSPPRADTGGSS 307
             P+ +PL + S+ H   + P P    P   P P  PA   G  +   L PP A      
Sbjct: 413 --PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS----- 465

Query: 308 SGGCSGPDSKHRTLPAPP------APTAWPAAGAPGAPNPAESRRGPGPAQGPP 355
                 P   H+  P PP       P   P    P  P+ +    GPG +  PP
Sbjct: 466 ----HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPP 515



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 50/176 (28%), Positives = 68/176 (38%), Gaps = 40/176 (22%)

Query: 83  PRPASLSPRAALAS--APGQKPQPAR---QAQLPRPVSGVRPPPRGRVGLSQAPGRPLGA 137
           P P +L P ++L++   P   P P +   Q+Q P P S  +PP     GL+Q+   P   
Sbjct: 410 PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ-PLPSSPAQPP-----GLTQSQNLPPPP 463

Query: 138 CARAK-GIRLVNPSPPRP--------PEPIPASAAVTSGLTARGPNTSATP---GPQKGR 185
            +    G+  V P PP          P PI      ++     GP TSA P   G     
Sbjct: 464 ASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASG 523

Query: 186 GSAERTNHIP-----------KDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHA 230
           GS    +  P            D +   +PPPP  PR P    S   +V   P HA
Sbjct: 524 GSIAGGSSCPLPTVQIKEEALDDAEEPESPPPP--PRSP----SPEPTVVDTPSHA 573



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 28/143 (19%), Positives = 51/143 (35%), Gaps = 5/143 (3%)

Query: 218 SSGLSVPTPPEH-----AGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPF 272
           S+  S+P+P ++     +  +++      P  +  + ++  PS+ P          P P 
Sbjct: 156 STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPS 215

Query: 273 FWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPA 332
             +     SP  + A  + +      P      + +     P S H      P P   P 
Sbjct: 216 ATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPL 275

Query: 333 AGAPGAPNPAESRRGPGPAQGPP 355
            G+ G P+     + P   QGPP
Sbjct: 276 TGSAGQPSAPSHAQPPLHGQGPP 298


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 87/354 (24%), Positives = 118/354 (33%), Gaps = 51/354 (14%)

Query: 29   ALSQPTLRHSASALRPPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLSADRWPR-PAS 87
            AL  PT    A +  PP    G    P  G  P+ +  P +G     +  A   P+ P +
Sbjct: 740  ALQAPTGVTPAPSSAPP----GTPQLPTPGPTPSATAVPPQGSPTASQ--APNQPQAPTA 793

Query: 88   LSPRAALASAPGQKPQPARQAQLPRPVSGVRP--PPRGRVGLSQAPGR---------PLG 136
              P   +  AP   PQ       P   S   P  P  G  G   AP           P G
Sbjct: 794  PVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPG 853

Query: 137  ACARAKGIRLVNPSPPRP----PEPIPASAAVTSGLTARGPNTSAT-PGPQKGRGSAERT 191
              +   G  L +P PP+P    P+     A + +   A  P+TS   P  Q    S +  
Sbjct: 854  PHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP 913

Query: 192  NHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLS 251
               P     +A P     P  P  +  +  +   PP  +G          P P       
Sbjct: 914  REQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPP------- 966

Query: 252  EVPSTRPLCATSSSH---SAPLPFFWSPLRNPSPR-PAPACGELRLGRLSPPRADTGGSS 307
              P+ +PL + S+ H   + P P    P   P P  PA   G  +   L PP A      
Sbjct: 967  --PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS----- 1019

Query: 308  SGGCSGPDSKHRTLPAPP------APTAWPAAGAPGAPNPAESRRGPGPAQGPP 355
                  P   H+  P PP       P   P    P  P+ +    GPG +  PP
Sbjct: 1020 ----HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPP 1069



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 50/176 (28%), Positives = 68/176 (38%), Gaps = 40/176 (22%)

Query: 83   PRPASLSPRAALAS--APGQKPQPAR---QAQLPRPVSGVRPPPRGRVGLSQAPGRPLGA 137
            P P +L P ++L++   P   P P +   Q+Q P P S  +PP     GL+Q+   P   
Sbjct: 964  PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ-PLPSSPAQPP-----GLTQSQNLPPPP 1017

Query: 138  CARAK-GIRLVNPSPPRP--------PEPIPASAAVTSGLTARGPNTSATP---GPQKGR 185
             +    G+  V P PP          P PI      ++     GP TSA P   G     
Sbjct: 1018 ASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASG 1077

Query: 186  GSAERTNHIP-----------KDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHA 230
            GS    +  P            D +   +PPPP  PR P    S   +V   P HA
Sbjct: 1078 GSIAGGSSCPLPTVQIKEEALDDAEEPESPPPP--PRSP----SPEPTVVDTPSHA 1127



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 28/143 (19%), Positives = 51/143 (35%), Gaps = 5/143 (3%)

Query: 218 SSGLSVPTPPEH-----AGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPF 272
           S+  S+P+P ++     +  +++      P  +  + ++  PS+ P          P P 
Sbjct: 710 STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPS 769

Query: 273 FWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPA 332
             +     SP  + A  + +      P      + +     P S H      P P   P 
Sbjct: 770 ATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPL 829

Query: 333 AGAPGAPNPAESRRGPGPAQGPP 355
            G+ G P+     + P   QGPP
Sbjct: 830 TGSAGQPSAPSHAQPPLHGQGPP 852


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 87/354 (24%), Positives = 118/354 (33%), Gaps = 51/354 (14%)

Query: 29   ALSQPTLRHSASALRPPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLSADRWPR-PAS 87
            AL  PT    A +  PP    G    P  G  P+ +  P +G     +  A   P+ P +
Sbjct: 740  ALQAPTGVTPAPSSAPP----GTPQLPTPGPTPSATAVPPQGSPTASQ--APNQPQAPTA 793

Query: 88   LSPRAALASAPGQKPQPARQAQLPRPVSGVRP--PPRGRVGLSQAPGR---------PLG 136
              P   +  AP   PQ       P   S   P  P  G  G   AP           P G
Sbjct: 794  PVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPG 853

Query: 137  ACARAKGIRLVNPSPPRP----PEPIPASAAVTSGLTARGPNTSAT-PGPQKGRGSAERT 191
              +   G  L +P PP+P    P+     A + +   A  P+TS   P  Q    S +  
Sbjct: 854  PHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPP 913

Query: 192  NHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLS 251
               P     +A P     P  P  +  +  +   PP  +G          P P       
Sbjct: 914  REQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPP------- 966

Query: 252  EVPSTRPLCATSSSH---SAPLPFFWSPLRNPSPR-PAPACGELRLGRLSPPRADTGGSS 307
              P+ +PL + S+ H   + P P    P   P P  PA   G  +   L PP A      
Sbjct: 967  --PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPAS----- 1019

Query: 308  SGGCSGPDSKHRTLPAPP------APTAWPAAGAPGAPNPAESRRGPGPAQGPP 355
                  P   H+  P PP       P   P    P  P+ +    GPG +  PP
Sbjct: 1020 ----HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPP 1069



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 50/176 (28%), Positives = 68/176 (38%), Gaps = 40/176 (22%)

Query: 83   PRPASLSPRAALAS--APGQKPQPAR---QAQLPRPVSGVRPPPRGRVGLSQAPGRPLGA 137
            P P +L P ++L++   P   P P +   Q+Q P P S  +PP     GL+Q+   P   
Sbjct: 964  PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQ-PLPSSPAQPP-----GLTQSQNLPPPP 1017

Query: 138  CARAK-GIRLVNPSPPRP--------PEPIPASAAVTSGLTARGPNTSATP---GPQKGR 185
             +    G+  V P PP          P PI      ++     GP TSA P   G     
Sbjct: 1018 ASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASG 1077

Query: 186  GSAERTNHIP-----------KDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHA 230
            GS    +  P            D +   +PPPP  PR P    S   +V   P HA
Sbjct: 1078 GSIAGGSSCPLPTVQIKEEALDDAEEPESPPPP--PRSP----SPEPTVVDTPSHA 1127



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 28/143 (19%), Positives = 51/143 (35%), Gaps = 5/143 (3%)

Query: 218 SSGLSVPTPPEH-----AGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPF 272
           S+  S+P+P ++     +  +++      P  +  + ++  PS+ P          P P 
Sbjct: 710 STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPS 769

Query: 273 FWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPA 332
             +     SP  + A  + +      P      + +     P S H      P P   P 
Sbjct: 770 ATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPL 829

Query: 333 AGAPGAPNPAESRRGPGPAQGPP 355
            G+ G P+     + P   QGPP
Sbjct: 830 TGSAGQPSAPSHAQPPLHGQGPP 852


>gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo
           sapiens]
          Length = 309

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 88/325 (27%), Positives = 114/325 (35%), Gaps = 67/325 (20%)

Query: 89  SPRAALASAPGQKPQPARQAQLPRPVSGV---RPPPRGRV--GLSQAPGRPLGACARAKG 143
           SP        G++PQ   Q Q   P  G    RPP  G    G    PG+P G   +  G
Sbjct: 28  SPSVISGKPEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQSQGPPPRPGKPEGPPPQG-G 86

Query: 144 IRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAA 203
            +   P PPRP +P         G   +G N S  P P+ G+         P+   +   
Sbjct: 87  NQSQGP-PPRPGKP--------EGQPPQGGNQSQGPPPRPGKPEGPP----PQGGNQSQG 133

Query: 204 PPP-PERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCAT 262
           PPP P +P  P  +G  G     PP   G       +    P      S+ P   P    
Sbjct: 134 PPPRPGKPEGPPPQG--GNQSQGPPPRPG-------KPEGPPPQGGNQSQGPPPHP---- 180

Query: 263 SSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGC-------SGPD 315
                 P P   +  + P PRP    G        PP+   GG+ S G         GP 
Sbjct: 181 -GKPEGPPPQGGNQSQGPPPRPGKPEGP-------PPQ---GGNQSQGPPPRPGKPEGPP 229

Query: 316 SKHRTLPAPPAPTAWPAAGAPGAPNPAESRRG-----PGPAQGPPSRRDEPRRVVIAARE 370
           S+    P  P P      G P  P P E  +      PG  QGPP     P++ +     
Sbjct: 230 SQGGNKPQGPPPHP----GKPQGPPPQEGNKPQRPPPPGRPQGPPPPGGNPQQPL--PPP 283

Query: 371 CGR-EGSELPPSGEETPGRRKSPSQ 394
            G+ +G   PP G    GR   P Q
Sbjct: 284 AGKPQGPPPPPQG----GRPHRPPQ 304



 Score = 55.5 bits (132), Expect = 9e-08
 Identities = 74/275 (26%), Positives = 96/275 (34%), Gaps = 44/275 (16%)

Query: 99  GQKPQPARQAQ--LPRPVSGVRPPPRG---RVGLSQAPGRPLGACARAKGIRLVNPSPPR 153
           G+ PQ   Q+Q   PRP     PPP+G     G    PG+P G   +  G +   P PPR
Sbjct: 59  GRPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQG-GNQSQGP-PPR 116

Query: 154 PPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPP-PERPRV 212
           P +P         G   +G N S  P P+ G+         P+   +   PPP P +P  
Sbjct: 117 PGKP--------EGPPPQGGNQSQGPPPRPGKPEGPP----PQGGNQSQGPPPRPGKPEG 164

Query: 213 PFCRGSSGLSVPTP-------PEHAGGRRKKFTRTRP-----LPRTSSFLSEVPSTRPLC 260
           P  +G +    P P       P   GG + +    RP      P      S+ P  RP  
Sbjct: 165 PPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRP-- 222

Query: 261 ATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRT 320
                   P     +  + P P P    G        P R    G   G    P   +  
Sbjct: 223 ---GKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGNKPQRPPPPGRPQG--PPPPGGNPQ 277

Query: 321 LPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPP 355
            P PP     PA    G P P +  R   P QG P
Sbjct: 278 QPLPP-----PAGKPQGPPPPPQGGRPHRPPQGQP 307



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 65/240 (27%), Positives = 88/240 (36%), Gaps = 47/240 (19%)

Query: 24  PRLAEALSQPTLRHSASALRPPRLSRGKDLKPRCG---RGPAHSPDPGEGCEAWRRLSAD 80
           PR  +   QP    + S   PPR  + +   P+ G   +GP   P   EG          
Sbjct: 94  PRPGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEG---------- 143

Query: 81  RWPRPA----SLSPRAALASAPGQKPQPARQAQLPRPVSGVR--PPPRG---RVGLSQAP 131
             P P     S  P        G  PQ   Q+Q P P  G    PPP+G     G    P
Sbjct: 144 --PPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKPEGPPPQGGNQSQGPPPRP 201

Query: 132 GRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERT 191
           G+P G   +  G +   P PPRP +P         G  ++G N    P P  G+      
Sbjct: 202 GKPEGPPPQG-GNQSQGP-PPRPGKP--------EGPPSQGGNKPQGPPPHPGKPQGPP- 250

Query: 192 NHIPKDKQRVAAPPPPERPRVPFCRGS---------SGLSVPTPPEHAGGRRKKFTRTRP 242
              P++  +   PPPP RP+ P   G          +G     PP   GGR  +  + +P
Sbjct: 251 ---PQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGRPHRPPQGQP 307


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 90/372 (24%), Positives = 126/372 (33%), Gaps = 70/372 (18%)

Query: 31  SQPTLRHSAS----ALRPPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLSADRWPRPA 86
           + P + H+ S    + RPP   R     P  G   +  P+P    +A+  L+      P 
Sbjct: 130 ASPQMFHTVSPGPPSARPP--CRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPP 187

Query: 87  SLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACARAKGIRL 146
            L+    + S     P+   +   P P     PPP   + L+ AP    GA  R+  +  
Sbjct: 188 RLAD--PVPSGGSSSPRFLPRGNAPSPA----PPPPPAISLN-APSYNWGAALRSSLVPS 240

Query: 147 VNPSPPRP---------PEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKD 197
              SPP P         P     S A+T        N  A PGP      +  T H+P  
Sbjct: 241 DLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLV 300

Query: 198 KQRVAAPPPPERPRVPFCRGSSGLSVPT--------PPEHAGGRRKKF------------ 237
              +   P  E P  P    SS LS           PP    GRR +             
Sbjct: 301 LGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLR 360

Query: 238 -TRTRP----------------LPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNP 280
            ++ RP                 PR S   +  P  +P      S    LP   S L  P
Sbjct: 361 PSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPI-LPSVLSLLGLP 419

Query: 281 SPRPAPACGELRL----GRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAP 336
           +P P+ + G   L      L PP   + GS       P  +H   P+ P  T+   +  P
Sbjct: 420 TPGPSHSDGSFNLLGSDAHLPPPPTLSSGSP------PQPRHPIQPSLPGTTSGSLSSVP 473

Query: 337 GAPNPAESRRGP 348
           GAP P  + + P
Sbjct: 474 GAPAPPAASKAP 485



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 95/376 (25%), Positives = 125/376 (33%), Gaps = 84/376 (22%)

Query: 31  SQPTLRHSASALRPPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLSADRWPRPASLSP 90
           S P L H + AL PP L    +L      GPA  P           +S+     P  L P
Sbjct: 256 SDPPLFHCSDALTPPPLPPSNNLPAH--PGPASQPP----------VSSATMHLPLVLGP 303

Query: 91  RAALASAPGQKPQPARQAQLPRPVSGVRPPP-------RGRVGLSQAPGRPLGACARAKG 143
                +  G    P   + L    +  + PP       +GR   +QAP     + + +  
Sbjct: 304 LGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAP-----SASHSSS 358

Query: 144 IRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAA 203
           +R     P RPP        V   L  RGP T     P++ R  A      P    +  +
Sbjct: 359 LRPSQRRPRRPP-------TVFRLLEGRGPQT-----PRRSRPRA------PAPVPQPFS 400

Query: 204 PPPPERPRVPFCRGSSGLSVPTP-PEHAGGRRKKF-------------TRTRPLPR---- 245
            P P +P +P      GL  PTP P H+ G                  + + P PR    
Sbjct: 401 LPEPSQPILPSVLSLLGL--PTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQ 458

Query: 246 ------TSSFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPAC--GELRLGRLS 297
                 TS  LS VP      A S +   P P   SP         PAC    L  G   
Sbjct: 459 PSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAF 518

Query: 298 P-PRADTGGSSSGGCSGPDSKHRTLP-------APPAP----TAWPAAGAPGAPNPAESR 345
           P P  + G + SG  +G       LP        PP+P    + +      G   P E  
Sbjct: 519 PFPSPEQGLALSG--AGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPL 576

Query: 346 RGPGPAQGPPSRRDEP 361
             P    GPP    EP
Sbjct: 577 LPPPGGPGPPLAPGEP 592



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 87/356 (24%), Positives = 117/356 (32%), Gaps = 49/356 (13%)

Query: 83  PRPASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACARAK 142
           P P+ L   +      G   QP  +  LP P  G  PP         APG P G      
Sbjct: 550 PPPSPLLNHSLFGVLTGGGGQPPPEPLLPPP-GGPGPP--------LAPGEPEGPSLLVA 600

Query: 143 GIRLVNPSPPRPPEPIPASAAVTS--GLTARGPNTSATPGPQKGRG--SAERTNHIPKDK 198
            +    PS   PP   P S  + S   L A GP      G  +G G  S E  + +  D 
Sbjct: 601 SLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGL-GDL 659

Query: 199 QRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEV--PST 256
             +  PP    P +     +   +   PP     +    +  +P P TSS  +    P  
Sbjct: 660 SPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGA 719

Query: 257 RPLCATSSSHSAPLPFFWSPL-----------RNPSPRPAPAC----GELRLGRLSPPRA 301
             L    S+   P P   SPL              SP   P+     G L  G+L     
Sbjct: 720 SSLGKAPSNSGRP-PQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLL 778

Query: 302 DTGGSS---SGGCSGPDSKHRTLPAPPAPTAWPA--AGAPGAPNPAESRRGPGPAQGPP- 355
             GG+    S   S      ++L  PP     P     +P +    E  R P  A  PP 
Sbjct: 779 PGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPH 838

Query: 356 SRRDEPRRVVIAARECGREG-----------SELPPSGEETPGRRKSPSQSCKKGG 400
              D P   ++  R  G+ G            E  P+    PG R+ P +   K G
Sbjct: 839 GSPDPPVPELLTGRGSGKRGRRGGGGLRGINGEARPARGRKPGSRREPGRLALKWG 894


>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
            1 [Homo sapiens]
          Length = 1250

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 95/387 (24%), Positives = 138/387 (35%), Gaps = 57/387 (14%)

Query: 32   QPTLRHSASALRPPR--LSRGKDLKPRC-----GRGPAHSPDPGEGCEAWRRLSADRWPR 84
            Q   +HS +  +PP   + + + +KP+      G  P   P P          SA    +
Sbjct: 674  QNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPG----SAMAQLK 729

Query: 85   PASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACARAKGI 144
            PA  +P     SAP   P P +  Q+   ++ V PP       +  P  P+ A       
Sbjct: 730  PAPCAPSLPQFSAP---PPPLKIHQVQH-ITQVAPP-------TPPPPPPIPA------- 771

Query: 145  RLVNPSPPRPPEPIPASAA---VTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRV 201
             L   +PP+P   IPA  +   V   +T   P T   P P   +  A   ++IP      
Sbjct: 772  PLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTP 831

Query: 202  AAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCA 261
              P PP  P +P  +       P+P        K+     P P T   +   P  +P+ A
Sbjct: 832  PVPVPP--PTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQP-LKPVPA 888

Query: 262  TSSSHSAPLPFF---WSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKH 318
              +  S P       W P   P P P             PP  +   SS      P S  
Sbjct: 889  NVAPQSPPAVKAKPKWQPSSIPVPSPD----------FPPPPPE---SSLVFPPPPPSPV 935

Query: 319  RTLPAPPAPTAWPAAGAPGAPNPAESR-RGPGPAQGPPSRRDEPRRVVIAARECGREGSE 377
               P PP PTA P     G+P    S+   PG  + PP+    P+R        G E  E
Sbjct: 936  PAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPT----PQRNSSIKSSSGAEHPE 991

Query: 378  -LPPSGEETPGRRKSPSQSCKKGGESI 403
               PS +    +   P++S     E++
Sbjct: 992  PKRPSVDSLVSKFTPPAESGSPSKETL 1018



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 68/284 (23%), Positives = 93/284 (32%), Gaps = 61/284 (21%)

Query: 83   PRPASLSPRAALASAPGQKPQPARQ-AQLPRPVSGVRPPPRGRVGLSQAPGRPLGACARA 141
            P PA+++P+    S P  K +P  Q + +P P     PPP         P   L      
Sbjct: 885  PVPANVAPQ----SPPAVKAKPKWQPSSIPVPSPDFPPPP---------PESSL------ 925

Query: 142  KGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQR- 200
                     PP PP P+PA         +  P+ S +PG +  + S+      P   QR 
Sbjct: 926  -------VFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRN 978

Query: 201  -------VAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEV 253
                    A  P P+RP V      S +S  TPP  +G   K+       P     L+  
Sbjct: 979  SSIKSSSGAEHPEPKRPSV-----DSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLS 1033

Query: 254  PSTRPLCATSSSHSAPLPF-----------FWSPLRNPSPRPAPACGELRLGRLSPPRAD 302
                P        SA  P            F SP  +    P P   EL L  +  P   
Sbjct: 1034 GVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVF 1093

Query: 303  TGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRR 346
            +G +S           +     P P  W       AP P   +R
Sbjct: 1094 SGNTSP----------KVAVVNPQPQQWSKMSVKKAPPPTRPKR 1127



 Score = 33.1 bits (74), Expect = 0.47
 Identities = 73/320 (22%), Positives = 96/320 (30%), Gaps = 80/320 (25%)

Query: 72  EAWRR---LSADRWPRPASLSPRAALASAPGQKPQPA----RQAQLPRPVSGVRPPPRGR 124
           EAW+R   L      R  S++ R   +  P   PQP       A  P P     PPP   
Sbjct: 579 EAWKRGTQLEESSKARMESMN-RPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPP--- 634

Query: 125 VGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTA----------RGPN 174
                 P  P              P PP PP P+P+ +A ++G  A          R  N
Sbjct: 635 -----PPPPP--------------PPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQN 675

Query: 175 TS-------ATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPF----------CRG 217
            S         P P   +  + +   +      V  PPPP  P  P           C  
Sbjct: 676 ASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAP 735

Query: 218 S-SGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFFWSP 276
           S    S P PP      +       P P         P   P+ A     + P P    P
Sbjct: 736 SLPQFSAPPPPLKIHQVQHITQVAPPTP---------PPPPPIPAPLPPQAPPKPLVTIP 786

Query: 277 LRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGAP 336
               +   AP   +      +PP              P  K    PA   P + P    P
Sbjct: 787 APTSTKTVAPVVTQAAPPTPTPP------------VPPAKKQPAFPASYIPPSPPTPPVP 834

Query: 337 GAPNPAESRRGPGPAQGPPS 356
             P P   ++    A+ PPS
Sbjct: 835 -VPPPTLPKQQSFCAKPPPS 853


>gi|153281158 dual specificity phosphatase 8 [Homo sapiens]
          Length = 625

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 97/333 (29%), Positives = 121/333 (36%), Gaps = 56/333 (16%)

Query: 87  SLSPRAALASAPGQK-------PQPARQAQLPRPVSGVRPPPRGRVGLSQAPGRPLGACA 139
           SL   AAL   PG         P PA  A LPR      PPP      S A G    A A
Sbjct: 299 SLKLLAALQGDPGTPSGTPEPPPSPAAGAPLPR-----LPPPTSE---SAATGN---AAA 347

Query: 140 RAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPK--- 196
           R  G+      PP PP P PA++A+  GL  RG + S+       R     +  I     
Sbjct: 348 REGGLS-AGGEPPAPPTP-PATSALQQGL--RGLHLSSDRLQDTNRLKRSFSLDIKSAYA 403

Query: 197 DKQRVAAPPPPERPRVP-FCRGSS------GLSVPTP--PEHAGGRRKKFTRTRPLPRTS 247
             +R   P PP+    P  C+  S      GLS P+P  P+ A   R +  R RP P   
Sbjct: 404 PSRRPDGPGPPDPGEAPKLCKLDSPSGAALGLSSPSPDSPDAAPEARPR-PRRRPRP--- 459

Query: 248 SFLSEVPSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSS 307
                 P+  P  A S +HS  L F        + R  P  G   L  LS P     G  
Sbjct: 460 ------PAGSP--ARSPAHSLGLNF------GDAARQTPRHG---LSALSAPGLPGPGQP 502

Query: 308 SG-GCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDEPRRVVI 366
           +G G   P       P+P  P  +   GA GA     +  G   A GP    D  RR   
Sbjct: 503 AGPGAWAPPLDSPGTPSPDGPWCFSPEGAQGAGGVLFAPFGRAGAPGPGGGSDLRRREAA 562

Query: 367 AARECGREGSELPPSGEETPGRRKSPSQSCKKG 399
            A               ET  +R+S     ++G
Sbjct: 563 RAEPRDARTGWPEEPAPETQFKRRSCQMEFEEG 595


>gi|182507165 thymus expressed gene 3-like [Homo sapiens]
          Length = 629

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 105/407 (25%), Positives = 133/407 (32%), Gaps = 63/407 (15%)

Query: 39  ASALRPPRLSRGKDLKPRCGRGPAHSPDPGEG---CEAWRRLSADRWPRPASLSPRAALA 95
           A A+R PR          CGR P  SPD G      + +      R  R  +  PR +  
Sbjct: 223 AVAMRSPR---------PCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPG 273

Query: 96  SAPGQKPQPARQAQLP---RPVSGVRPPPRGRVGLSQAPGRPLG--ACARAKGIRLVNPS 150
            A G   +     Q P    P  G   P R    L +  G P    A +RA      + +
Sbjct: 274 GADGGPRRQNSVRQRPPDASPSPGSARPAR-EPSLERVGGHPTSPAALSRAWASSWESEA 332

Query: 151 PPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGR----GSAERTNHIPKDKQR-VAAPP 205
            P P  P  A +   S    R       PG Q       G A R    P  + R V   P
Sbjct: 333 APEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSVEQSP 392

Query: 206 PPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSS 265
           P ERPR     G  G            R +K +R++         S VPS  P   T+  
Sbjct: 393 PRERPRAA---GRRGRMAEASGRRGSPRARKASRSQSETSLLGRASAVPSGPPKYPTAER 449

Query: 266 HSAPLPFFWSPLRNPSPR-PAPACGELRL-----------GRLSPPRADT------GGSS 307
                P    P R P+P   A A G  R            GR   PRA        G S 
Sbjct: 450 EEPRPP---RPRRGPAPTLAAQAAGSCRRWRSTAEIDAADGRRVRPRAPAARVPGPGPSP 506

Query: 308 SG-------GCSGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAES--RRGPGPAQGPPSRR 358
           S        GC+G DS+       P     PA G  G    +ES    G  PA    S  
Sbjct: 507 SAPQRRLLYGCAGSDSECSAGRLGPLGRRGPAGGVGGGYGESESSASEGESPAFSSASSD 566

Query: 359 DE-------PRRVVIAARECGREGSELPPSGEETPGRRKSPSQSCKK 398
            +       P+++V A    G       P+G      +   S + KK
Sbjct: 567 SDGSGGLVWPQQLVAATAASGGGAGAGAPAGPAKVFVKIKASHALKK 613



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 80/307 (26%), Positives = 104/307 (33%), Gaps = 63/307 (20%)

Query: 123 GRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQ 182
           GR+G S+  G  + A  R K +   +PS P   E + A AAV    +A  P    + GP+
Sbjct: 147 GRLGPSEPRG--IYASERPKSLGDASPSAP---EVVGARAAVPRSFSAPYPTAGGSAGPE 201

Query: 183 KGRGSAER------------TNHIPKDKQRVAAPPPPERPRVPFC--------------R 216
               SAER             + +     R    PP + P                   R
Sbjct: 202 -ACSSAERRARAGPFLTPSPLHAVAMRSPRPCGRPPTDSPDAGGAGRPLDGYISALLRRR 260

Query: 217 GSSGLSVP-TPPEHAGG--RRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSH---SAPL 270
              G   P T P  A G  RR+   R RP   + S  S  P+  P       H    A L
Sbjct: 261 RRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAAL 320

Query: 271 PFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDS--KHRTLPAPPAPT 328
              W+        P PA         +PP A          S PDS  + R + A   P 
Sbjct: 321 SRAWASSWESEAAPEPA---------APPAAP---------SPPDSPAEGRLVKAQYIPG 362

Query: 329 AWPAAGAPGAPNPAESRRGPGPAQGPPSRRDEPRRVVIAARECGREGSELPPSGEETPGR 388
           A   A   G P  A  R+ P   +G    +  PR      R  GR G     SG     R
Sbjct: 363 A--QAATRGLPGRAARRKPPPLTRGRSVEQSPPRE---RPRAAGRRGRMAEASGRRGSPR 417

Query: 389 RKSPSQS 395
            +  S+S
Sbjct: 418 ARKASRS 424


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
           sapiens]
          Length = 247

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 75/267 (28%), Positives = 89/267 (33%), Gaps = 68/267 (25%)

Query: 99  GQKPQPARQAQLPRPVSGVR--PPPRG---RVGLSQAPGRPLGACARAKGIRLVNPSPPR 153
           G++PQ   Q Q P P  G    PPP+G     G    PG+P G   +        P  P 
Sbjct: 38  GRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPG 97

Query: 154 PPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVP 213
            PE  P      S  T   P     P PQ G  S     H P        PPPP +P  P
Sbjct: 98  KPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQS-----HRP--------PPPPGKPERP 144

Query: 214 FCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPSTRPLCATSSSHSAPLPFF 273
             +G  G     PP H G                      P   P    + S SA     
Sbjct: 145 PPQG--GNQSQGPPPHPGK---------------------PEGPPPQEGNKSRSA----- 176

Query: 274 WSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKHRTLPA---PPAPTAW 330
               R+P  +P             PP+ +  G+   G   P       PA   P  P A 
Sbjct: 177 ----RSPPGKPQ-----------GPPQQE--GNKPQGPPPPGKPQGPPPAGGNPQQPQAP 219

Query: 331 PAAGAPGAPNPAESRRGPGPAQG--PP 355
           PA    G P P +  R P PAQG  PP
Sbjct: 220 PAGKPQGPPPPPQGGRPPRPAQGQQPP 246



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 26/86 (30%), Positives = 34/86 (39%), Gaps = 15/86 (17%)

Query: 38  SASALRPPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLSADRWPRPAS---LSPRAAL 94
           S SA  PP   +G   +   G  P   P PG+           + P PA      P+A  
Sbjct: 173 SRSARSPPGKPQGPPQQE--GNKPQGPPPPGK----------PQGPPPAGGNPQQPQAPP 220

Query: 95  ASAPGQKPQPARQAQLPRPVSGVRPP 120
           A  P   P P +  + PRP  G +PP
Sbjct: 221 AGKPQGPPPPPQGGRPPRPAQGQQPP 246


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 113/449 (25%), Positives = 154/449 (34%), Gaps = 99/449 (22%)

Query: 2   SELESGEIRSEEGRPTTESRIRPR----LAEALSQPTLRHSAS--ALRPPRLSRG----- 50
           S   S   RS   +P   +   PR    L+ + S P  RH  S  A  PP+         
Sbjct: 360 SSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQ 419

Query: 51  --KDLKPRCGRGPAHSPDP---GEGCEAWRRLSADRWPRPASLSP-------RAALASAP 98
             +  K R    P  +       +G E     S    PR   LS        + A A + 
Sbjct: 420 SNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSV 479

Query: 99  GQKPQPARQAQLPRPVSGV-------RPP----PRGRVGLSQ--APGRPLGACARAK--- 142
            Q+ Q  RQ Q     SG        RP       G VG  +  +P R      R +   
Sbjct: 480 QQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKE 539

Query: 143 ----GIRLVNPSPP-----RPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNH 193
               G R  +PSPP     R P P P         T   P    TP P   R S     +
Sbjct: 540 TSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRR---TPTPPPRRRTPSPPPRRRSPSPRRY 596

Query: 194 IPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEV 253
            P  ++R +  PPP+R            S P PP+          R  P P         
Sbjct: 597 SPPIQRRYSPSPPPKRRTA---------SPPPPPKR---------RASPSP--------- 629

Query: 254 PSTRPLCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSG 313
           P  R +     SHS P     SP+   + R +P+         SP R+     S      
Sbjct: 630 PPKRRV-----SHSPPPKQRSSPV---TKRRSPSLSSKHRKGSSPSRSTREARS----PQ 677

Query: 314 PDSKHRTLPAPPAP--TAWPAAGAPGAPNPAESRRGPGPAQGP---PSRRDEPRRVVIAA 368
           P+ +H   P P AP  ++ P     GA +  + R+ P P+  P    SR  EP+++  AA
Sbjct: 678 PNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAA 737

Query: 369 ----RECGREGSELPPSGEETPGRRKSPS 393
               +   R  S    SG   P  +K P+
Sbjct: 738 SPSPQSVRRVSSSRSVSGSPEPAAKKPPA 766



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 68/266 (25%), Positives = 98/266 (36%), Gaps = 48/266 (18%)

Query: 148 NPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPP 207
           +PSP R   P+      +   + R    S +P P   +   E+T  +P+   +V  P   
Sbjct: 179 SPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEK--KEKTPELPEPSVKVKEPSVQ 236

Query: 208 ERPRVPFCRGSSGLSVPTP----------PEHAGGRRKKFTRTRPLPRTSSFLSEVPSTR 257
           E         S  L VP P          PE    + K+  +TRP  R+ S       +R
Sbjct: 237 EATST-----SDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSR 291

Query: 258 PLCATSSSHSAPLPFF------WSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGC 311
                S SH+ P          +SP R PSPR  P+       R +PPR           
Sbjct: 292 -----SPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPR-----RRTPPRR---------- 331

Query: 312 SGPDSKHRTLPAPPAPTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRDEP----RRVVIA 367
             P  +HR   +P       +A   G+ + + S R   P + PP R   P    RR+  +
Sbjct: 332 MPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPS 391

Query: 368 ARECGREGSELPPSGEETPGRRKSPS 393
           A    R     PP+    P  R SP+
Sbjct: 392 ASPPRRRHRPSPPA-TPPPKTRHSPT 416



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 93/387 (24%), Positives = 127/387 (32%), Gaps = 59/387 (15%)

Query: 43  RPPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLSADRWPRPASLSPRAALASAPGQKP 102
           RP   SR K       R P+H+                   RP       + + +P ++P
Sbjct: 275 RPRSRSRSKSRSRTRSRSPSHT-------------------RPRRRHRSRSRSYSPRRRP 315

Query: 103 QPARQAQLPR--PVSGVRPPPRGRVGLSQAPGRPLGACARAKGIRLVNPSPPRPPEPIPA 160
            P R+    R  P   + PPPR R   S    R   + + +      + S  R P   P 
Sbjct: 316 SPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPP 375

Query: 161 SAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQRVAAPPPPERPRVPFCRGSSG 220
               +     R  + SA+P  ++ R S   T   P   +    P    R R      S G
Sbjct: 376 KRTSSPPRKTRRLSPSASPPRRRHRPSPPATP--PPKTRHSPTPQQSNRTRKSRVSVSPG 433

Query: 221 LSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSE--------------VPSTRPLCATSSSH 266
            +     +H G  +++     P PR    LSE              V   R     +   
Sbjct: 434 RTSGKVTKHKGTEKRESPSPAPKPRKVE-LSESEEDKGGKMAAADSVQQRRQYRRQNQQS 492

Query: 267 SAPLPFFWSPLRNPSPRPAPACGEL-RLGRLSPPR-ADTGGSSSGGCSGPDSKHRTLPAP 324
           S+      S       R     GE+ R  R SP R A          + P  + R  P+P
Sbjct: 493 SSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSP 552

Query: 325 P------APTAWPAAGAPGAPNPAESRRGPGPAQGPPSRRD-EPRRVVIAARECGREGSE 377
           P      +P+  P       P P   RR P P   PP RR   PRR    +    R  S 
Sbjct: 553 PPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSP---PPRRRSPSPRRY---SPPIQRRYSP 606

Query: 378 LPPSGEET------PGRRKSPSQSCKK 398
            PP    T      P RR SPS   K+
Sbjct: 607 SPPPKRRTASPPPPPKRRASPSPPPKR 633



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 52/227 (22%), Positives = 79/227 (34%), Gaps = 42/227 (18%)

Query: 31  SQPTLRHSASALRPPRLSRGKDLKPRCGRGPAHSPDPGEGCEAWRRLSADRWPRPASLSP 90
           S P  R +AS   PP+        P+  R  +HSP P +      R S     R  SLS 
Sbjct: 607 SPPPKRRTASPPPPPKRRASPSPPPK--RRVSHSPPPKQ------RSSPVTKRRSPSLSS 658

Query: 91  RAALASAPGQKPQPARQAQ---------LPRPVSGVRPPPRGRVGLSQAPGRPLGACARA 141
           +    S+P +  + AR  Q          PR       PP  R G S +P R        
Sbjct: 659 KHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPST 718

Query: 142 KGIRLVNPSP------------PRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAE 189
           + IR V+ +P            P+    + +S +V+           A P P + +  + 
Sbjct: 719 RPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPST 778

Query: 190 RTNHIPKDKQRVAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKK 236
             +     K+  +  P P  PR                +  GG++KK
Sbjct: 779 NWSPAVPVKKAKSPTPSPSPPR-------------NSDQEGGGKKKK 812


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.132    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,967,489
Number of Sequences: 37866
Number of extensions: 2011408
Number of successful extensions: 20725
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 283
Number of HSP's successfully gapped in prelim test: 2076
Number of HSP's that attempted gapping in prelim test: 11105
Number of HSP's gapped (non-prelim): 8270
length of query: 414
length of database: 18,247,518
effective HSP length: 105
effective length of query: 309
effective length of database: 14,271,588
effective search space: 4409920692
effective search space used: 4409920692
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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