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Search of human proteins with 11141861
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11141861 claudin 9 [Homo sapiens]
(217 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11141861 claudin 9 [Homo sapiens] 434 e-122
gi|153792768 claudin 6 [Homo sapiens] 321 3e-88
gi|4502875 claudin 3 [Homo sapiens] 295 2e-80
gi|4502877 claudin 4 [Homo sapiens] 291 4e-79
gi|195947374 claudin 5 [Homo sapiens] 243 9e-65
gi|195947372 claudin 5 [Homo sapiens] 243 9e-65
gi|10863887 claudin 1 [Homo sapiens] 210 9e-55
gi|153792186 claudin 7 [Homo sapiens] 205 2e-53
gi|40788011 claudin 8 [Homo sapiens] 201 3e-52
gi|6912316 claudin 17 [Homo sapiens] 200 7e-52
gi|183979975 claudin 19 isoform b [Homo sapiens] 194 6e-50
gi|183979973 claudin 19 isoform a [Homo sapiens] 192 1e-49
gi|225703142 claudin 14 [Homo sapiens] 187 6e-48
gi|21536294 claudin 14 [Homo sapiens] 187 6e-48
gi|225703138 claudin 14 [Homo sapiens] 187 6e-48
gi|6912314 claudin 14 [Homo sapiens] 187 6e-48
gi|225703140 claudin 14 [Homo sapiens] 187 6e-48
gi|9966781 claudin 2 [Homo sapiens] 174 5e-44
gi|47716519 claudin 20 [Homo sapiens] 134 5e-32
gi|5921465 claudin 10 isoform b [Homo sapiens] 129 2e-30
gi|7656981 claudin 15 [Homo sapiens] 129 2e-30
gi|169166402 PREDICTED: claudin-24-like [Homo sapiens] 124 8e-29
gi|169167239 PREDICTED: claudin-24-like [Homo sapiens] 123 1e-28
gi|169166931 PREDICTED: claudin-24-like [Homo sapiens] 123 1e-28
gi|162417973 claudin 22 [Homo sapiens] 120 1e-27
gi|7705961 claudin 18 isoform 1 [Homo sapiens] 112 3e-25
gi|157820127 claudin-like [Homo sapiens] 111 4e-25
gi|50345279 claudin 18 isoform 2 [Homo sapiens] 110 9e-25
gi|33598916 claudin 10 isoform a [Homo sapiens] 107 6e-24
gi|231569235 claudin 10 isoform a_i1 [Homo sapiens] 92 4e-19
>gi|11141861 claudin 9 [Homo sapiens]
Length = 217
Score = 434 bits (1116), Expect = e-122
Identities = 217/217 (100%), Positives = 217/217 (100%)
Query: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG
Sbjct: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLT 120
QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLT
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLT 120
Query: 121 AGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGL 180
AGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGL
Sbjct: 121 AGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGL 180
Query: 181 LCCTCPPPQVERPRGPRLGYSIPSRSGASGLDKRDYV 217
LCCTCPPPQVERPRGPRLGYSIPSRSGASGLDKRDYV
Sbjct: 181 LCCTCPPPQVERPRGPRLGYSIPSRSGASGLDKRDYV 217
>gi|153792768 claudin 6 [Homo sapiens]
Length = 220
Score = 321 bits (822), Expect = 3e-88
Identities = 156/220 (70%), Positives = 185/220 (84%), Gaps = 3/220 (1%)
Query: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MAS G+++LG+ L +LGW+ LVSCALP+WKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG
Sbjct: 1 MASAGMQILGVVLTLLGWVNGLVSCALPMWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLT 120
QMQCKVYDSLLALPQDLQAARALCVIALL+AL GLLV + GA+CTTCVE++ +KAR+VLT
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLVLT 120
Query: 121 AGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGL 180
+G++ +++G+L LIPVCWTAHAII+DFYNPLVAEA KRELGASLYLGWAA+ LL+LGGGL
Sbjct: 121 SGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGGGL 180
Query: 181 LCCTCPPPQVERPRGPRLGYSIPSRS---GASGLDKRDYV 217
LCCTCP + P YS + + G S ++YV
Sbjct: 181 LCCTCPSGGSQGPSHYMARYSTSAPAISRGPSEYPTKNYV 220
>gi|4502875 claudin 3 [Homo sapiens]
Length = 220
Score = 295 bits (755), Expect = 2e-80
Identities = 140/220 (63%), Positives = 178/220 (80%), Gaps = 6/220 (2%)
Query: 3 STGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQM 62
S GLE+ G LAVLGWLGT+V CALP+W+V+AFIG++I+ +Q +WEGLWM+CVVQSTGQM
Sbjct: 2 SMGLEITGTALAVLGWLGTIVCCALPMWRVSAFIGSNIITSQNIWEGLWMNCVVQSTGQM 61
Query: 63 QCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLTAG 122
QCKVYDSLLALPQDLQAARAL V+A+LLA GLLVA+ GAQCT CV+D+ AKA+I + AG
Sbjct: 62 QCKVYDSLLALPQDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAG 121
Query: 123 VILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGLLC 182
V+ LLA +L L+PV W+A+ II+DFYNP+V EA KRE+GA LY+GWAAAAL +LGG LLC
Sbjct: 122 VLFLLAALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLC 181
Query: 183 CTCPPPQVERPRGPRLGYSIPSRSG-----ASGLDKRDYV 217
C+CPP + ++ ++ YS P +G +G D++DYV
Sbjct: 182 CSCPPRE-KKYTATKVVYSAPRSTGPGASLGTGYDRKDYV 220
>gi|4502877 claudin 4 [Homo sapiens]
Length = 209
Score = 291 bits (744), Expect = 4e-79
Identities = 133/209 (63%), Positives = 174/209 (83%), Gaps = 3/209 (1%)
Query: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MAS GL+++G+ LAVLGWL ++ CALP+W+VTAFIG++IV +Q +WEGLWM+CVVQSTG
Sbjct: 1 MASMGLQVMGIALAVLGWLAVMLCCALPMWRVTAFIGSNIVTSQTIWEGLWMNCVVQSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLT 120
QMQCKVYDSLLALPQDLQAARAL +I++++A LG+L+++ G +CT C+EDE AKA+ ++
Sbjct: 61 QMQCKVYDSLLALPQDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIV 120
Query: 121 AGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGL 180
AGV+ LLAG++V++PV WTAH IIQDFYNPLVA KRE+GASLY+GWAA+ LL+LGGGL
Sbjct: 121 AGVVFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGL 180
Query: 181 LCCTCPPPQVERPRGPRLGYSIPSRSGAS 209
LCC C PP+ ++P + YS + AS
Sbjct: 181 LCCNC-PPRTDKPYSAK--YSAARSAAAS 206
>gi|195947374 claudin 5 [Homo sapiens]
Length = 303
Score = 243 bits (620), Expect = 9e-65
Identities = 121/222 (54%), Positives = 160/222 (72%), Gaps = 9/222 (4%)
Query: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
M S LE+LG+ L ++GW G +++C LP+W+VTAF+ ++IV AQ W+GLWMSCVVQSTG
Sbjct: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLT 120
MQCKVYDS+LAL ++QAARAL V A+LLA + L V + GAQCTTCV AKAR+ LT
Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205
Query: 121 AGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGL 180
GV+ L G+L L+P+CW A+ ++++FY+P V + K ELGA+LY+GWAA ALLM+GG L
Sbjct: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265
Query: 181 LCC---TCP-PPQVERPRGPRLGYSIPSRSGASG-LDKRDYV 217
LCC C P + P + YS P R A+G DK++YV
Sbjct: 266 LCCGAWVCTGRPDLSFP----VKYSAPRRPTATGDYDKKNYV 303
>gi|195947372 claudin 5 [Homo sapiens]
Length = 303
Score = 243 bits (620), Expect = 9e-65
Identities = 121/222 (54%), Positives = 160/222 (72%), Gaps = 9/222 (4%)
Query: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
M S LE+LG+ L ++GW G +++C LP+W+VTAF+ ++IV AQ W+GLWMSCVVQSTG
Sbjct: 86 MGSAALEILGLVLCLVGWGGLILACGLPMWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTG 145
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLT 120
MQCKVYDS+LAL ++QAARAL V A+LLA + L V + GAQCTTCV AKAR+ LT
Sbjct: 146 HMQCKVYDSVLALSTEVQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALT 205
Query: 121 AGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGL 180
GV+ L G+L L+P+CW A+ ++++FY+P V + K ELGA+LY+GWAA ALLM+GG L
Sbjct: 206 GGVLYLFCGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGGCL 265
Query: 181 LCC---TCP-PPQVERPRGPRLGYSIPSRSGASG-LDKRDYV 217
LCC C P + P + YS P R A+G DK++YV
Sbjct: 266 LCCGAWVCTGRPDLSFP----VKYSAPRRPTATGDYDKKNYV 303
>gi|10863887 claudin 1 [Homo sapiens]
Length = 211
Score = 210 bits (534), Expect = 9e-55
Identities = 105/218 (48%), Positives = 145/218 (66%), Gaps = 8/218 (3%)
Query: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MA+ GL+LLG LA LGW+G +VS ALP W++ ++ G++IV AQ ++EGLWMSCV QSTG
Sbjct: 1 MANAGLQLLGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVE-DEGAKARIVL 119
Q+QCKV+DSLL L LQA RAL V+ +LL ++ + VA G +C C+E DE K R+ +
Sbjct: 61 QIQCKVFDSLLNLSSTLQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAV 120
Query: 120 TAGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGG 179
G I LLAG+ +L+ W + I+Q+FY+P+ + E G +L+ GWAAA+L +LGG
Sbjct: 121 IGGAIFLLAGLAILVATAWYGNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGA 180
Query: 180 LLCCTCPPPQVERPRGPRLGYSIPSRSGASGLDKRDYV 217
LLCC+CP P PR P + +SG +DYV
Sbjct: 181 LLCCSCPRKTTSYPT-PR---PYPKPAPSSG---KDYV 211
>gi|153792186 claudin 7 [Homo sapiens]
Length = 211
Score = 205 bits (522), Expect = 2e-53
Identities = 96/218 (44%), Positives = 147/218 (67%), Gaps = 8/218 (3%)
Query: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MA++GL+LLG ++A+LGW+G + A+P W+++++ G++I+ AQ +++GLWM CV QSTG
Sbjct: 1 MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTC-VEDEGAKARIVL 119
M CK+YDS+LAL LQA RAL V++L+L L + VA G +CT C +D+ KARI +
Sbjct: 61 MMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAM 120
Query: 120 TAGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGG 179
G+I ++AG+ L+ W H I+ DFYNPL+ +K E G ++++GWA +AL++LGG
Sbjct: 121 GGGIIFIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGA 180
Query: 180 LLCCTCPPPQVERPRGPRLGYSIPSRSGASGLDKRDYV 217
LL C+CP + + GY +P RS ++YV
Sbjct: 181 LLSCSCPGNE------SKAGYRVP-RSYPKSNSSKEYV 211
>gi|40788011 claudin 8 [Homo sapiens]
Length = 225
Score = 201 bits (512), Expect = 3e-52
Identities = 104/207 (50%), Positives = 139/207 (67%), Gaps = 9/207 (4%)
Query: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MA+ LE+ G+ L +G +GT+ +P W+V+AFI N+IVV + WEGLWM+CV Q+
Sbjct: 1 MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANI 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVED-EGAKARIVL 119
+MQCK+YDSLLAL DLQAAR L A +++ L ++AI G +CT C D E KA I+L
Sbjct: 61 RMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILL 120
Query: 120 TAGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGG 179
TAG+I ++ G++VLIPV W A+AII+DFYN +V A KRELG +LYLGW A +L++GG
Sbjct: 121 TAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGA 180
Query: 180 LLCCT--CPPPQVERPRGPRLGYSIPS 204
L CC C + YSIPS
Sbjct: 181 LFCCVFCC------NEKSSSYRYSIPS 201
>gi|6912316 claudin 17 [Homo sapiens]
Length = 224
Score = 200 bits (509), Expect = 7e-52
Identities = 102/206 (49%), Positives = 144/206 (69%), Gaps = 4/206 (1%)
Query: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MA L++ G+ L LG +GTL + LP W+V+AF+G++I+V + +WEGLWM+C+ Q+
Sbjct: 1 MAFYPLQIAGLVLGFLGMVGTLATTLLPQWRVSAFVGSNIIVFERLWEGLWMNCIRQARV 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCV-EDEGAKARIVL 119
++QCK Y SLLALP L+ ARAL +A+ L+L+ LL+ I G + C +E AKA ++
Sbjct: 61 RLQCKFYSSLLALPPALETARALMCVAVALSLIALLIGICGMKQVQCTGSNERAKAYLLG 120
Query: 120 TAGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGG 179
T+GV+ +L GI VLIPV WTA+ II+DFYNP + KRELGA+L+LGWA+AA+L +GGG
Sbjct: 121 TSGVLFILTGIFVLIPVSWTANIIIRDFYNPAIHIGQKRELGAALFLGWASAAVLFIGGG 180
Query: 180 LLC--CTCPPPQVERPRGPRLGYSIP 203
LLC C C + + R P GY +P
Sbjct: 181 LLCGFCCCNRKK-QGYRYPVPGYRVP 205
>gi|183979975 claudin 19 isoform b [Homo sapiens]
Length = 211
Score = 194 bits (492), Expect = 6e-50
Identities = 98/218 (44%), Positives = 142/218 (65%), Gaps = 8/218 (3%)
Query: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MA++GL+LLG LA+ GW+G + S ALP WK +++ G++I+ A ++EGLWMSC QSTG
Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEG-AKARIVL 119
Q+QCK+YDSLLAL +Q+ARAL V+A+LL + +++++ G +CT + AK R+ +
Sbjct: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
Query: 120 TAGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGG 179
G + +LAG+ L V W A + Q+F+NP + E G +L++GWA+A L +LGG
Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
Query: 180 LLCCTCPPPQVERPRGPRLGYSIPSRSGASGLDKRDYV 217
LCCTCP P ERP Y P S A+ R+YV
Sbjct: 181 FLCCTCPEP--ERPNSSPQPYR-PGPSAAA----REYV 211
>gi|183979973 claudin 19 isoform a [Homo sapiens]
Length = 224
Score = 192 bits (489), Expect = 1e-49
Identities = 95/210 (45%), Positives = 138/210 (65%), Gaps = 4/210 (1%)
Query: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MA++GL+LLG LA+ GW+G + S ALP WK +++ G++I+ A ++EGLWMSC QSTG
Sbjct: 1 MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEG-AKARIVL 119
Q+QCK+YDSLLAL +Q+ARAL V+A+LL + +++++ G +CT + AK R+ +
Sbjct: 61 QVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAI 120
Query: 120 TAGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGG 179
G + +LAG+ L V W A + Q+F+NP + E G +L++GWA+A L +LGG
Sbjct: 121 AGGALFILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGS 180
Query: 180 LLCCTCPPPQVERPRGPRLGYSIPSRSGAS 209
LCCTCP P ERP Y P S A+
Sbjct: 181 FLCCTCPEP--ERPNSSPQPYR-PGPSAAA 207
>gi|225703142 claudin 14 [Homo sapiens]
Length = 239
Score = 187 bits (475), Expect = 6e-48
Identities = 94/206 (45%), Positives = 135/206 (65%), Gaps = 6/206 (2%)
Query: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MAST ++LLG L+ LG +GTL++ LP W+ TA +G +I+ A +GLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLT 120
QC++Y SLLALPQDLQAARAL VI+ LL+ + A+ G +CT C + AK +
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 AGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGL 180
G + +LAG+L ++ V WT + ++Q+FYNPL+ +K E+G +LYLG+ +++L ++GG L
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCCTCPPPQVERPRGPRLGYSIPSRS 206
LC +C Q E P P Y P R+
Sbjct: 181 LCLSC---QDEAPYRP---YQAPPRA 200
>gi|21536294 claudin 14 [Homo sapiens]
Length = 239
Score = 187 bits (475), Expect = 6e-48
Identities = 94/206 (45%), Positives = 135/206 (65%), Gaps = 6/206 (2%)
Query: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MAST ++LLG L+ LG +GTL++ LP W+ TA +G +I+ A +GLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLT 120
QC++Y SLLALPQDLQAARAL VI+ LL+ + A+ G +CT C + AK +
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 AGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGL 180
G + +LAG+L ++ V WT + ++Q+FYNPL+ +K E+G +LYLG+ +++L ++GG L
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCCTCPPPQVERPRGPRLGYSIPSRS 206
LC +C Q E P P Y P R+
Sbjct: 181 LCLSC---QDEAPYRP---YQAPPRA 200
>gi|225703138 claudin 14 [Homo sapiens]
Length = 239
Score = 187 bits (475), Expect = 6e-48
Identities = 94/206 (45%), Positives = 135/206 (65%), Gaps = 6/206 (2%)
Query: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MAST ++LLG L+ LG +GTL++ LP W+ TA +G +I+ A +GLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLT 120
QC++Y SLLALPQDLQAARAL VI+ LL+ + A+ G +CT C + AK +
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 AGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGL 180
G + +LAG+L ++ V WT + ++Q+FYNPL+ +K E+G +LYLG+ +++L ++GG L
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCCTCPPPQVERPRGPRLGYSIPSRS 206
LC +C Q E P P Y P R+
Sbjct: 181 LCLSC---QDEAPYRP---YQAPPRA 200
>gi|6912314 claudin 14 [Homo sapiens]
Length = 239
Score = 187 bits (475), Expect = 6e-48
Identities = 94/206 (45%), Positives = 135/206 (65%), Gaps = 6/206 (2%)
Query: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MAST ++LLG L+ LG +GTL++ LP W+ TA +G +I+ A +GLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLT 120
QC++Y SLLALPQDLQAARAL VI+ LL+ + A+ G +CT C + AK +
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 AGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGL 180
G + +LAG+L ++ V WT + ++Q+FYNPL+ +K E+G +LYLG+ +++L ++GG L
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCCTCPPPQVERPRGPRLGYSIPSRS 206
LC +C Q E P P Y P R+
Sbjct: 181 LCLSC---QDEAPYRP---YQAPPRA 200
>gi|225703140 claudin 14 [Homo sapiens]
Length = 239
Score = 187 bits (475), Expect = 6e-48
Identities = 94/206 (45%), Positives = 135/206 (65%), Gaps = 6/206 (2%)
Query: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MAST ++LLG L+ LG +GTL++ LP W+ TA +G +I+ A +GLWM CV STG
Sbjct: 1 MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLT 120
QC++Y SLLALPQDLQAARAL VI+ LL+ + A+ G +CT C + AK +
Sbjct: 61 IYQCQIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAIL 120
Query: 121 AGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGL 180
G + +LAG+L ++ V WT + ++Q+FYNPL+ +K E+G +LYLG+ +++L ++GG L
Sbjct: 121 GGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGTL 180
Query: 181 LCCTCPPPQVERPRGPRLGYSIPSRS 206
LC +C Q E P P Y P R+
Sbjct: 181 LCLSC---QDEAPYRP---YQAPPRA 200
>gi|9966781 claudin 2 [Homo sapiens]
Length = 230
Score = 174 bits (441), Expect = 5e-44
Identities = 80/185 (43%), Positives = 122/185 (65%)
Query: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MAS GL+L+G L +LG LGTLV+ LP WK ++++G SIV A +GLWM C STG
Sbjct: 1 MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLT 120
QC +Y +LL LP D+QAA+A+ V + ++ L ++++ G +CT ++ AK R+ +
Sbjct: 61 ITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVA 120
Query: 121 AGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGL 180
GV +L G+L IPV W H I++DFY+PLV +++K E+G +LYLG ++ ++ G +
Sbjct: 121 GGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGII 180
Query: 181 LCCTC 185
LC +C
Sbjct: 181 LCFSC 185
>gi|47716519 claudin 20 [Homo sapiens]
Length = 219
Score = 134 bits (338), Expect = 5e-32
Identities = 72/185 (38%), Positives = 102/185 (55%)
Query: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MAS GL+LL LA+ G G L + LP WKV + ++I+ A V GLWM C STG
Sbjct: 1 MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTG 60
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLT 120
C + S+L+LP +QAARA V+A +L+ LG+ + G +CT D K+
Sbjct: 61 MFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFA 120
Query: 121 AGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGL 180
GV + AGI LI W II +F + V E+ K E G ++Y+G+ +A LL + G +
Sbjct: 121 GGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMI 180
Query: 181 LCCTC 185
C +C
Sbjct: 181 FCTSC 185
>gi|5921465 claudin 10 isoform b [Homo sapiens]
Length = 228
Score = 129 bits (324), Expect = 2e-30
Identities = 71/184 (38%), Positives = 106/184 (57%), Gaps = 6/184 (3%)
Query: 1 MASTGLELLGMTLAVLGWLGTLVSCALPL--WKVTAFIGNSIVVAQVVWEGLWMSCVVQS 58
MAST E++ +++ GW+ LVS LP WKV+ G I A W LW +CV S
Sbjct: 1 MASTASEIIAFMVSISGWV--LVSSTLPTDYWKVSTIDGTVITTA-TYWANLWKACVTDS 57
Query: 59 TGQMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIV 118
TG CK + S+LAL +QA R L + A+ L G + A+ G +CT + AKA+I
Sbjct: 58 TGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIA 117
Query: 119 LTAGVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGG 178
AG++ +L+G+ + A+ I +F++PL E K ELGA+L++GWA A+L ++GG
Sbjct: 118 CLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQ-KYELGAALFIGWAGASLCIIGG 176
Query: 179 GLLC 182
+ C
Sbjct: 177 VIFC 180
>gi|7656981 claudin 15 [Homo sapiens]
Length = 228
Score = 129 bits (324), Expect = 2e-30
Identities = 72/184 (39%), Positives = 104/184 (56%), Gaps = 3/184 (1%)
Query: 3 STGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQM 62
S +E G +A +G L V+ W+V+ GN ++ ++E LW SC S G
Sbjct: 2 SMAVETFGFFMATVGLLMLGVTLPNSYWRVSTVHGN-VITTNTIFENLWFSCATDSLGVY 60
Query: 63 QCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDE-GAKARIVLTA 121
C + S+LAL +QA RAL + A+LL LGLL+ I G +CT E KA++ TA
Sbjct: 61 NCWEFPSMLALSGYIQACRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLAATA 120
Query: 122 GVILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGLL 181
G + +LAGI ++ + W A I +DF++PL K ELG +LYLGW+A+ + +LGG L
Sbjct: 121 GALHILAGICGMVAISWYAFNITRDFFDPLY-PGTKYELGPALYLGWSASLISILGGLCL 179
Query: 182 CCTC 185
C C
Sbjct: 180 CSAC 183
>gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 124 bits (310), Expect = 8e-29
Identities = 68/182 (37%), Positives = 107/182 (58%), Gaps = 5/182 (2%)
Query: 4 TGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQ 63
T ++ +G+ L++LGW+ ++++ LP WK N + + GLW +CV+Q MQ
Sbjct: 7 TAMQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWTM---GLWQTCVIQEEVGMQ 63
Query: 64 CKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDE-GAKARIVLTAG 122
CK +DS LALP +L+ +R L ++ L LGLLV+ G C E + K R+++ G
Sbjct: 64 CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
Query: 123 VILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKR-ELGASLYLGWAAAALLMLGGGLL 181
++ +GI L+PV W AH +Q+F++ V + + R E G +L+LGW A L+LGG LL
Sbjct: 124 ILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
Query: 182 CC 183
C
Sbjct: 184 NC 185
>gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 123 bits (308), Expect = 1e-28
Identities = 68/182 (37%), Positives = 106/182 (58%), Gaps = 5/182 (2%)
Query: 4 TGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQ 63
T ++ +G+ L+ LGW+ ++++ LP WK N + + GLW +CV+Q MQ
Sbjct: 7 TAMQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWTM---GLWQTCVIQEEVGMQ 63
Query: 64 CKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDE-GAKARIVLTAG 122
CK +DS LALP +L+ +R L ++ L LGLLV+ G C E + K R+++ G
Sbjct: 64 CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
Query: 123 VILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKR-ELGASLYLGWAAAALLMLGGGLL 181
++ +GI L+PV W AH +Q+F++ V + + R E G +L+LGW A L+LGG LL
Sbjct: 124 ILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
Query: 182 CC 183
C
Sbjct: 184 NC 185
>gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]
Length = 220
Score = 123 bits (308), Expect = 1e-28
Identities = 68/182 (37%), Positives = 106/182 (58%), Gaps = 5/182 (2%)
Query: 4 TGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQ 63
T ++ +G+ L+ LGW+ ++++ LP WK N + + GLW +CV+Q MQ
Sbjct: 7 TAMQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWTM---GLWQTCVIQEEVGMQ 63
Query: 64 CKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDE-GAKARIVLTAG 122
CK +DS LALP +L+ +R L ++ L LGLLV+ G C E + K R+++ G
Sbjct: 64 CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
Query: 123 VILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKR-ELGASLYLGWAAAALLMLGGGLL 181
++ +GI L+PV W AH +Q+F++ V + + R E G +L+LGW A L+LGG LL
Sbjct: 124 ILSWASGITALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
Query: 182 CC 183
C
Sbjct: 184 NC 185
>gi|162417973 claudin 22 [Homo sapiens]
Length = 220
Score = 120 bits (300), Expect = 1e-27
Identities = 68/182 (37%), Positives = 106/182 (58%), Gaps = 5/182 (2%)
Query: 4 TGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQ 63
T +L G++L++LGW+ + ++ LP WK N + + GLW +CV+Q MQ
Sbjct: 7 TVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTM---GLWQTCVIQEEVGMQ 63
Query: 64 CKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDE-GAKARIVLTAG 122
CK +DS LALP +L+ +R L ++ L LGLLV+ G C E + K R+++ G
Sbjct: 64 CKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGG 123
Query: 123 VILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKR-ELGASLYLGWAAAALLMLGGGLL 181
++ +G+ L+PV W AH +Q+F++ V + + R E G +L+LGW A L+LGG LL
Sbjct: 124 ILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLL 183
Query: 182 CC 183
C
Sbjct: 184 HC 185
>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
Length = 261
Score = 112 bits (279), Expect = 3e-25
Identities = 58/197 (29%), Positives = 108/197 (54%), Gaps = 13/197 (6%)
Query: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
M++T +++ L++LG G + + + +W N V + +EGLW SCV QS+G
Sbjct: 1 MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNP-VTSVFQYEGLWRSCVRQSSG 59
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVE-DEGAKARIVL 119
+C+ Y ++L LP LQA RAL ++ ++L +GLLV+I +C ++ AKA + L
Sbjct: 60 FTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
Query: 120 TAGVILLLAGILVLIPVCWTAHAIIQDFY-----------NPLVAEALKRELGASLYLGW 168
T+G++ +++G+ + V A+ ++ +F+ + + GA+L++GW
Sbjct: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
Query: 169 AAAALLMLGGGLLCCTC 185
A L ++GG ++C C
Sbjct: 180 VAGGLTLIGGVMMCIAC 196
>gi|157820127 claudin-like [Homo sapiens]
Length = 229
Score = 111 bits (278), Expect = 4e-25
Identities = 69/179 (38%), Positives = 97/179 (54%), Gaps = 7/179 (3%)
Query: 6 LELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVW-EGLWMSCVVQSTGQMQC 64
++L G+ L++LGW+ + V+ LP WK N + W G+W CV + C
Sbjct: 9 VQLGGLLLSLLGWVCSCVTTILPQWKTLNLELNEMET----WIMGIWEVCVDREEVATVC 64
Query: 65 KVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGA-KARIVLTAGV 123
K ++S L+LPQ+LQ AR L V + L LLGLL+ G++C K R+ L
Sbjct: 65 KAFESFLSLPQELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRT 124
Query: 124 ILLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKR-ELGASLYLGWAAAALLMLGGGLL 181
+ A L+PV W AHA IQDF++ + + + R E G +LYLGWAA L LGG LL
Sbjct: 125 LEASASATTLLPVSWVAHATIQDFWDDSIPDIIPRWEFGGALYLGWAAGIFLALGGLLL 183
>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
Length = 261
Score = 110 bits (275), Expect = 9e-25
Identities = 60/197 (30%), Positives = 109/197 (55%), Gaps = 13/197 (6%)
Query: 1 MASTGLELLGMTLAVLGWLGTLVSCALPLWKVTAFIGNSIVVAQVVWEGLWMSCVVQSTG 60
MA T + LG ++++G G + + + W T + N+ V A ++GLW SCV +S+G
Sbjct: 1 MAVTACQGLGFVVSLIGIAGIIAATCMDQWS-TQDLYNNPVTAVFNYQGLWRSCVRESSG 59
Query: 61 QMQCKVYDSLLALPQDLQAARALCVIALLLALLGLLVAITGAQCTTCVE-DEGAKARIVL 119
+C+ Y +LL LP LQA RAL ++ ++L +GLLV+I +C ++ AKA + L
Sbjct: 60 FTECRGYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTL 119
Query: 120 TAGVILLLAGILVLIPVCWTAHAIIQDFY-----------NPLVAEALKRELGASLYLGW 168
T+G++ +++G+ + V A+ ++ +F+ + + GA+L++GW
Sbjct: 120 TSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGW 179
Query: 169 AAAALLMLGGGLLCCTC 185
A L ++GG ++C C
Sbjct: 180 VAGGLTLIGGVMMCIAC 196
>gi|33598916 claudin 10 isoform a [Homo sapiens]
Length = 226
Score = 107 bits (268), Expect = 6e-24
Identities = 57/168 (33%), Positives = 96/168 (57%), Gaps = 3/168 (1%)
Query: 16 LGWLGTLVSCALPL-WKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQCKVYDSLLALP 74
+G G LV+ WKVT +S++ A V++GLWM+C + G C+ + ++ +
Sbjct: 13 VGGFGALVAATTSNEWKVTTR-ASSVITATWVYQGLWMNCAGNALGSFHCRPHFTIFKVA 71
Query: 75 QDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLTAGVILLLAGILVLI 134
+QA R L + A+ L G + A+ G +CT + AKA+I AG++ +L+G+ +
Sbjct: 72 GYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMT 131
Query: 135 PVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGLLC 182
A+ I +F++PL E K ELGA+L++GWA A+L ++GG + C
Sbjct: 132 GCSLYANKITTEFFDPLFVEQ-KYELGAALFIGWAGASLCIIGGVIFC 178
>gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]
Length = 207
Score = 91.7 bits (226), Expect = 4e-19
Identities = 55/168 (32%), Positives = 88/168 (52%), Gaps = 22/168 (13%)
Query: 16 LGWLGTLVSCALPL-WKVTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQCKVYDSLLALP 74
+G G LV+ WKVT +S++ A V++GLWM+C
Sbjct: 13 VGGFGALVAATTSNEWKVTTR-ASSVITATWVYQGLWMNCAGY----------------- 54
Query: 75 QDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLTAGVILLLAGILVLI 134
+QA R L + A+ L G + A+ G +CT + AKA+I AG++ +L+G+ +
Sbjct: 55 --IQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMT 112
Query: 135 PVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGLLC 182
A+ I +F++PL E K ELGA+L++GWA A+L ++GG + C
Sbjct: 113 GCSLYANKITTEFFDPLFVEQ-KYELGAALFIGWAGASLCIIGGVIFC 159
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.139 0.442
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,267,977
Number of Sequences: 37866
Number of extensions: 342103
Number of successful extensions: 1524
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 1444
Number of HSP's gapped (non-prelim): 53
length of query: 217
length of database: 18,247,518
effective HSP length: 98
effective length of query: 119
effective length of database: 14,536,650
effective search space: 1729861350
effective search space used: 1729861350
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.