Guide to the Human Genome
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Search of human proteins with 111120318

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|111120318 NK6 transcription factor related, locus 1 [Homo
sapiens]
         (367 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|111120318 NK6 transcription factor related, locus 1 [Homo sap...   729   0.0  
gi|28912912 NK6 transcription factor related, locus 2 [Homo sapi...   331   6e-91
gi|89257348 homeo box HB9 [Homo sapiens]                              102   7e-22
gi|50355978 T-cell leukemia homeobox 3 [Homo sapiens]                 100   2e-21
gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens]                   91   2e-18
gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens]                   87   2e-17
gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]                86   5e-17
gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]                  85   1e-16
gi|116805350 homeo box (H6 family) 1 [Homo sapiens]                    84   2e-16
gi|126090909 engrailed homeobox 1 [Homo sapiens]                       84   3e-16
gi|157743259 H6 family homeobox 3 [Homo sapiens]                       82   6e-16
gi|4506049 hematopoietically expressed homeobox [Homo sapiens]         82   1e-15
gi|14149611 empty spiracles homeobox 2 [Homo sapiens]                  82   1e-15
gi|157426823 NK2 homeobox 4 [Homo sapiens]                             81   2e-15
gi|116174748 developing brain homeobox 2 [Homo sapiens]                81   2e-15
gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]                  80   4e-15
gi|70608170 H6 family homeobox 2 [Homo sapiens]                        79   8e-15
gi|94536800 empty spiracles homolog 1 [Homo sapiens]                   78   1e-14
gi|118582284 msh homeobox 1 [Homo sapiens]                             78   1e-14
gi|22749179 NK6 homeobox 3 [Homo sapiens]                              77   2e-14
gi|64225290 distal-less homeobox 1 isoform 1 [Homo sapiens]            77   2e-14
gi|11386181 H2.0-like homeobox [Homo sapiens]                          77   2e-14
gi|121114296 caudal type homeobox 1 [Homo sapiens]                     77   2e-14
gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  77   3e-14
gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  77   3e-14
gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  77   3e-14
gi|197333837 notochord homeobox [Homo sapiens]                         76   5e-14
gi|226437602 NK1 homeobox 2 [Homo sapiens]                             75   7e-14
gi|153218470 BarH-like homeobox 1 [Homo sapiens]                       75   9e-14
gi|13273315 homeobox B4 [Homo sapiens]                                 74   2e-13

>gi|111120318 NK6 transcription factor related, locus 1 [Homo
           sapiens]
          Length = 367

 Score =  729 bits (1883), Expect = 0.0
 Identities = 367/367 (100%), Positives = 367/367 (100%)

Query: 1   MLAVGAMEGTRQSAFLLSSPPLAALHSMAEMKTPLYPAAYPPLPAGPPSSSSSSSSSSSP 60
           MLAVGAMEGTRQSAFLLSSPPLAALHSMAEMKTPLYPAAYPPLPAGPPSSSSSSSSSSSP
Sbjct: 1   MLAVGAMEGTRQSAFLLSSPPLAALHSMAEMKTPLYPAAYPPLPAGPPSSSSSSSSSSSP 60

Query: 61  SPPLGTHNPGGLKPPATGGLSSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASP 120
           SPPLGTHNPGGLKPPATGGLSSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASP
Sbjct: 61  SPPLGTHNPGGLKPPATGGLSSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASP 120

Query: 121 SGSSSSSSSSASASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPS 180
           SGSSSSSSSSASASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPS
Sbjct: 121 SGSSSSSSSSASASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPS 180

Query: 181 AAAVAAVGRYPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTR 240
           AAAVAAVGRYPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTR
Sbjct: 181 AAAVAAVGRYPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTR 240

Query: 241 PTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMA 300
           PTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMA
Sbjct: 241 PTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMA 300

Query: 301 TAKKKQDSETERLKGASENEEEDDDYNKPLDPNSDDEKITQLLKKHKSSSGGGGGLLLHA 360
           TAKKKQDSETERLKGASENEEEDDDYNKPLDPNSDDEKITQLLKKHKSSSGGGGGLLLHA
Sbjct: 301 TAKKKQDSETERLKGASENEEEDDDYNKPLDPNSDDEKITQLLKKHKSSSGGGGGLLLHA 360

Query: 361 SEPESSS 367
           SEPESSS
Sbjct: 361 SEPESSS 367


>gi|28912912 NK6 transcription factor related, locus 2 [Homo
           sapiens]
          Length = 277

 Score =  331 bits (849), Expect = 6e-91
 Identities = 189/356 (53%), Positives = 215/356 (60%), Gaps = 89/356 (25%)

Query: 7   MEGTRQSAFLLSSPPLAALHSMAEMKTPLYPAAYPPLPAGPPSSSSSSSSSSSPSPPLGT 66
           M+  R  AF+LSS PLAALH+MAEMKT L+P A                           
Sbjct: 1   MDTNRPGAFVLSSAPLAALHNMAEMKTSLFPYAL-------------------------- 34

Query: 67  HNPGGLKPPATGGLSSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASPSGSSSS 126
             P G K PA GGL +      QL   TPHGI+DIL RP                     
Sbjct: 35  QGPAGFKAPALGGLGA------QLPLGTPHGISDILGRP--------------------- 67

Query: 127 SSSSASASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAA 186
                                   ++  GLL GLPR + L+      G+YF P+AA    
Sbjct: 68  ----------------------VGAAGGGLLGGLPRLNGLASSA---GVYFGPAAAVARG 102

Query: 187 VGRYPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQ 246
              YPKPLAELPGR PIFWPGV+Q  PWRD RLA     G +L DKDGK+KH+RPTFSGQ
Sbjct: 103 ---YPKPLAELPGRPPIFWPGVVQGAPWRDPRLAGPAPAGGVL-DKDGKKKHSRPTFSGQ 158

Query: 247 QIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMATAKKKQ 306
           QIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRK+HAAEMA+AKKKQ
Sbjct: 159 QIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQ 218

Query: 307 DSETERLKGASENEEEDDDYNKPLDPNSDDEKITQLLKKHKSSS-------GGGGG 355
           DS+ E+LK    + E+DD+YN+PLDPNSDDEKIT+LLKKHK S+       GGG G
Sbjct: 219 DSDAEKLKVGGSDAEDDDEYNRPLDPNSDDEKITRLLKKHKPSNLALVSPCGGGAG 274


>gi|89257348 homeo box HB9 [Homo sapiens]
          Length = 401

 Score =  102 bits (253), Expect = 7e-22
 Identities = 104/356 (29%), Positives = 149/356 (41%), Gaps = 49/356 (13%)

Query: 11  RQSAFLLSSPPLAALHSMAEMKTPLYPAAYPPLPAGPPSSSSSSSSSSSPSPPLGTHNPG 70
           R  A L   PP AA    A +      AA      G      +S  +S    P  +  P 
Sbjct: 8   RIDALLAVDPPRAASAQSAPLALVTSLAAAASGTGGGGGGGGASGGTSGSCSPASSEPPA 67

Query: 71  GLKPPATGGLSSLGSPPQQLSAATPHGINDILSRPS-MPVASGAALPSASPSGSSSSSSS 129
               PA    +   SPP+ L+A        +L +P  +    G         G    +  
Sbjct: 68  A---PADRLRAESPSPPRLLAAHCA-----LLPKPGFLGAGGGGGGTGGGHGGPHHHAHP 119

Query: 130 SASASSASAAAAAAAAAAAAASSPAGLL--AGLPRFSSLSPPPPPPGLY-FSPSAAAVAA 186
            A+A++A+AAAAAAA   A    P G    AGLP  ++L   P    +Y +S +AAA A 
Sbjct: 120 GAAAAAAAAAAAAAAGGLALGLHPGGAQGGAGLPAQAALYGHP----VYGYSAAAAAAAL 175

Query: 187 VGRYPKPLAELP---GRTPI-------FWPGVMQSPPWRDARLAC----------TPHQG 226
            G++P      P   G  P           G  Q   W  A  A           +  Q 
Sbjct: 176 AGQHPALSYSYPQVQGAHPAHPADPIKLGAGTFQLDQWLRASTAGMILPKMPDFNSQAQS 235

Query: 227 SILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQN 286
           ++L    GK +  R  F+ QQ+  LE  F+  KYL+ P+R  +A SL +TE+QVK+WFQN
Sbjct: 236 NLL----GKCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQN 291

Query: 287 RRTKWRKKHAAEMATAKKKQDSETERLK----GASENEEEDDDYNKPLDPNSDDEK 338
           RR KW++        AK++   E E+ K    GA +   E+    + L P +  +K
Sbjct: 292 RRMKWKRS-----KKAKEQAAQEAEKQKGGGGGAGKGGAEEPGAEELLGPPAPGDK 342


>gi|50355978 T-cell leukemia homeobox 3 [Homo sapiens]
          Length = 291

 Score =  100 bits (249), Expect = 2e-21
 Identities = 86/263 (32%), Positives = 119/263 (45%), Gaps = 29/263 (11%)

Query: 91  SAATPH-------GINDILSRPSMPVA------SGAALPSASPSGSSSSSSSSASASSAS 137
           SA TPH       GI+ IL+ P    A       GA+     P G   ++  S  AS A 
Sbjct: 6   SAQTPHPHEPISFGIDQILNSPDQDSAPAPRGPDGASYLGGPPGGRPGATYPSLPASFAG 65

Query: 138 AAAAAAAAAAAAAS---SPAGLLAGLPRFSSLS---PPPPPPGLYFSPSAAAVAAVGRYP 191
             A    A + + +   +PAG++  +P    L    PPP P  L   PS   V+++G   
Sbjct: 66  LGAPFEDAGSYSVNLSLAPAGVIR-VPAHRPLPGAVPPPLPSALPAMPSVPTVSSLGGLN 124

Query: 192 KPLAELPGR-TPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIFA 250
            P  E   R     +       P+   R    P+Q         KRK  R +FS  QI  
Sbjct: 125 FPWMESSRRFVKDRFTAAAALTPFTVTRRIGHPYQNRT----PPKRKKPRTSFSRVQICE 180

Query: 251 LEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMATAKKKQDSET 310
           LEK F + KYLA  ERA LA SL MT++QVK WFQNRRTKWR++ A E    ++ +  + 
Sbjct: 181 LEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAEE----REAERQQA 236

Query: 311 ERLKGASENEEEDDDYNKPLDPN 333
            RL    +++      N  + P+
Sbjct: 237 SRLMLQLQHDAFQKSLNDSIQPD 259


>gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens]
          Length = 284

 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 73/210 (34%), Positives = 96/210 (45%), Gaps = 18/210 (8%)

Query: 97  GINDILSRPSMPVASGAALPSASPSGSSSSSSSSASASSASAAAAAAAAAAAAASSPAGL 156
           GI+ ILS P  P   G         G   + + S     AS    A + A    SS  G 
Sbjct: 20  GIDQILSGPETP--GGGLGLGRGGQGHGENGAFSGGYHGASGYGPAGSLAPLPGSSGVGP 77

Query: 157 LAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRYPKPLAELPGRTPIFWPGVMQSPPWRD 216
             G+ R  +  P P PP     P+  A A  G  P  L    G   + +P +     +  
Sbjct: 78  -GGVIRVPAHRPLPVPP-----PAGGAPAVPG--PSGLGGAGGLAGLTFPWMDSGRRFAK 129

Query: 217 ARL--ACTPHQGSILLDKD------GKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERAR 268
            RL  A +P  G+  +          KRK  R +FS  Q+  LE+ F + KYLA  ERA 
Sbjct: 130 DRLTAALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLASAERAA 189

Query: 269 LAYSLGMTESQVKVWFQNRRTKWRKKHAAE 298
           LA +L MT++QVK WFQNRRTKWR++ A E
Sbjct: 190 LAKALRMTDAQVKTWFQNRRTKWRRQTAEE 219


>gi|5031757 T-cell leukemia homeobox 1 [Homo sapiens]
          Length = 330

 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 75/255 (29%), Positives = 109/255 (42%), Gaps = 47/255 (18%)

Query: 52  SSSSSSSSPSPPLGTHNPGGLKPPATGGLSSLGSPPQQLSAATPHGINDILSRPSMPVAS 111
           S++++ +  +   GT  PGG   PA GG +    P         + +N       M +A 
Sbjct: 62  SAAATGAGGAGAYGTGGPGGPGGPAGGGGACSMGP-----LTGSYNVN-------MALAG 109

Query: 112 GAALPSASPSGSSSSSSSSASASSASAAAAAA-AAAAAAASSPAGLLAGLPRFSSLSPPP 170
           G       P G   SS  + + S+A      A    A A + P  L  GLP   S+   P
Sbjct: 110 GPG-----PGGGGGSSGGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSV---P 161

Query: 171 PPPGLYFSPSAAAVAAVGRYPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILL 230
             PG+                         T + +P +  +  +   R    P+Q     
Sbjct: 162 AMPGVN----------------------NLTGLTFPWMESNRRYTKDRFTGHPYQNRT-- 197

Query: 231 DKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTK 290
               K+K  R +F+  QI  LEK F + KYLA  ERA LA +L MT++QVK WFQNRRTK
Sbjct: 198 --PPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTK 255

Query: 291 WRKKHAAEMATAKKK 305
           WR++ A E    +++
Sbjct: 256 WRRQTAEEREAERQQ 270


>gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]
          Length = 411

 Score = 85.9 bits (211), Expect = 5e-17
 Identities = 73/262 (27%), Positives = 109/262 (41%), Gaps = 11/262 (4%)

Query: 34  PLYPAAYPPLPAGPPSSSSSSSSSSSPSPPLGTHNPGGLKPPATGGLSSLGSPPQQLSAA 93
           P+ PAA  P  + P + + ++S     +  L      G      GG+ + G+ P   +A 
Sbjct: 68  PVAPAACAPCASAPCAPAPAASGRPPRAEELERRALAG-----AGGVGAAGAEPP--NAG 120

Query: 94  TPHGINDILSRPSMPVASGAALPSASPSGSSSSSSSSASASSASAAAAAAAAAAAAASSP 153
            P    +  +  +   +SG    S S                 +    AA  A  A    
Sbjct: 121 DPFKAGEAETNDTNGYSSGGGGHSPSADSGDEVPDDEDDDEDEAPETEAARGAEEARGGG 180

Query: 154 AGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRYPKPLAELPGRTPIFWPGVMQSPP 213
            GL A        +     PG     +AA      R   P+A+ P       PG   + P
Sbjct: 181 GGLGARGSGCQGAAETDASPGATVDEAAAPGP---RENSPVAQGPPGGAAA-PGGAGTTP 236

Query: 214 WRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSL 273
              A  A    + +    K GK +  R  F+ +Q+ ALE  F+ T+YL+  ER  LA SL
Sbjct: 237 QGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSL 296

Query: 274 GMTESQVKVWFQNRRTKWRKKH 295
            +TE+QVK+WFQNRRTKW+K++
Sbjct: 297 SLTETQVKIWFQNRRTKWKKQN 318



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 20/56 (35%), Positives = 22/56 (39%), Gaps = 4/56 (7%)

Query: 29  AEMKTPLYPAAYPPLPAGPPSSSSSSSSSSSPSPP----LGTHNPGGLKPPATGGL 80
           A+   P      P   AGP +      S  SPSPP    LG H P G      GGL
Sbjct: 321 ADTSAPTGGGGGPGPGAGPGTGLPGGLSPLSPSPPMGAPLGMHGPAGYPAHGPGGL 376


>gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]
          Length = 814

 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 73/262 (27%), Positives = 108/262 (41%), Gaps = 11/262 (4%)

Query: 34  PLYPAAYPPLPAGPPSSSSSSSSSSSPSPPLGTHNPGGLKPPATGGLSSLGSPPQQLSAA 93
           P+ PAA  P  + P + + ++S     +  L      G      GG+ + G+ P   +A 
Sbjct: 471 PVAPAACAPCASAPCAPAPAASGRPPRAEELERRALAG-----AGGVGAAGAEPP--NAG 523

Query: 94  TPHGINDILSRPSMPVASGAALPSASPSGSSSSSSSSASASSASAAAAAAAAAAAAASSP 153
            P    +  +  +   +SG    S S                 +    AA  A  A    
Sbjct: 524 DPFKAGEAETNDTNGYSSGGGGHSPSADSGDEVPDDEDDDEDEAPETEAARGAEEARGGG 583

Query: 154 AGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRYPKPLAELPGRTPIFWPGVMQSPP 213
            GL A        +     PG     +AA      R   P+A  P       PG   + P
Sbjct: 584 GGLGARGSGCQGAAETDASPGATVDEAAAPGP---RENSPVAPGPPGGAAA-PGGAGTTP 639

Query: 214 WRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSL 273
              A  A    + +    K GK +  R  F+ +Q+ ALE  F+ T+YL+  ER  LA SL
Sbjct: 640 QGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSL 699

Query: 274 GMTESQVKVWFQNRRTKWRKKH 295
            +TE+QVK+WFQNRRTKW+K++
Sbjct: 700 SLTETQVKIWFQNRRTKWKKQN 721



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 20/56 (35%), Positives = 22/56 (39%), Gaps = 4/56 (7%)

Query: 29  AEMKTPLYPAAYPPLPAGPPSSSSSSSSSSSPSPP----LGTHNPGGLKPPATGGL 80
           A+   P      P   AGP +      S  SPSPP    LG H P G      GGL
Sbjct: 724 ADTSAPTGGGGGPGPGAGPGTGLPGGLSPLSPSPPMGAPLGMHGPAGYPAHGPGGL 779


>gi|116805350 homeo box (H6 family) 1 [Homo sapiens]
          Length = 348

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 47/115 (40%), Positives = 67/115 (58%), Gaps = 3/115 (2%)

Query: 188 GRYPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQ 247
           G   +  AEL  R P    G  ++    +   A    +G + +   G++K TR  FS  Q
Sbjct: 158 GAVQREAAELAARGPA--AGTEEASELAEVPAAAGETRGGVGVG-GGRKKKTRTVFSRSQ 214

Query: 248 IFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMATA 302
           +F LE TF+  +YL+  ERA LA SL +TE+QVK+WFQNRR KW+++ AAE+  A
Sbjct: 215 VFQLESTFDLKRYLSSAERAGLAASLQLTETQVKIWFQNRRNKWKRQLAAELEAA 269



 Score = 30.4 bits (67), Expect = 2.6
 Identities = 24/58 (41%), Positives = 29/58 (50%), Gaps = 7/58 (12%)

Query: 146 AAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPS----AAAVAAVGRYPKPLAELPG 199
           AAAAA  PA L   L   +  +P PPPP L FS +     AA  A    P   A++PG
Sbjct: 292 AAAAAGPPATLPFPL---APAAPAPPPPLLGFSGALAYPLAAFPAAASVPFLRAQMPG 346


>gi|126090909 engrailed homeobox 1 [Homo sapiens]
          Length = 392

 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 64/227 (28%), Positives = 103/227 (45%), Gaps = 7/227 (3%)

Query: 70  GGLKPPATGGLSSLGSPPQQLSAATPHGINDILSRPSMPVAS-GAALPSASPSGSSSSSS 128
           GG +     G ++ G  P         G   +L  P         + P+A+ +G+S + +
Sbjct: 138 GGGRVERDRGQTAAGRDPVHPLGTRAPGAASLLCAPDANCGPPDGSQPAAAGAGASKAGN 197

Query: 129 SSASASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVG 188
            +A+A++A+AA AAAAAAAAA  S  G   G         P      Y      A+  +G
Sbjct: 198 PAAAAAAAAAAVAAAAAAAAAKPSDTG---GGGSGGGAGSPGAQGTKYPEHGNPAILLMG 254

Query: 189 RYPK-PLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKR-KHTRPTFSGQ 246
                P+ +   + P+ WP  +    + D R +  P    +   K+ K  K  R  F+ +
Sbjct: 255 SANGGPVVKTDSQQPLVWPAWVYCTRYSD-RPSSGPRTRKLKKKKNEKEDKRPRTAFTAE 313

Query: 247 QIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRK 293
           Q+  L+  F+  +Y+    R  LA  L + ESQ+K+WFQN+R K +K
Sbjct: 314 QLQRLKAEFQANRYITEQRRQTLAQELSLNESQIKIWFQNKRAKIKK 360



 Score = 37.7 bits (86), Expect = 0.016
 Identities = 33/105 (31%), Positives = 45/105 (42%), Gaps = 11/105 (10%)

Query: 110 ASGAALPSASPSGSSSSSSSSASASSASAAAAAAAAAAAAASSP----AGLLAGLPRFSS 165
           A GAA  +A+P G S S S  AS SS S +   +   +   + P    A  L  L     
Sbjct: 15  ALGAAA-AATPGGLSLSLSPGASGSSGSGSDGDSVPVSPQPAPPSPPAAPCLPPLAHHPH 73

Query: 166 LSPPPPPPGLYFSPSAAAVAAVGRYPKPLAELPGRTPIFWPGVMQ 210
           L P PPP      P    +AA    P+P A+L   T  F   +++
Sbjct: 74  LPPHPPP------PPPQHLAAPAHQPQPAAQLHRTTNFFIDNILR 112


>gi|157743259 H6 family homeobox 3 [Homo sapiens]
          Length = 357

 Score = 82.4 bits (202), Expect = 6e-16
 Identities = 80/280 (28%), Positives = 113/280 (40%), Gaps = 49/280 (17%)

Query: 41  PPLPAGPPSSS-SSSSSSSSPSPPLGTHNPGGLKPPATGGLSSLGSP-------PQQLSA 92
           PP P  PP +  + +S++++ +        G L+  A   LS +G         P Q  A
Sbjct: 45  PPKPQPPPRTLFAPASAAAAAAAAAAAAAKGALEGAAGFALSQVGDLAFPRFEIPAQRFA 104

Query: 93  ATPHGINDILS--RPSMPVASGAALPSASPSGSSSSSSSSASASSASAAAAAAAAAAAAA 150
              H +    +   P     +G  LP    S  +    SS              A+    
Sbjct: 105 LPAHYLERSPAWWYPYTLTPAGGHLPRPEASEKALLRDSSP-------------ASGTDR 151

Query: 151 SSPAGLLAGLPRFSSLSPPPPPPGLYFSPSA--------AAVAAVGRYPKPLAELPGRTP 202
            SP  LL   P    L    P   +     +        AA  A G      A  PG   
Sbjct: 152 DSPEPLLKADPDHKELDSKSPDEIILEESDSEESKKEGEAAPGAAGASVGAAAATPGAED 211

Query: 203 IFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLA 262
             W    +SP   + + AC             ++K TR  FS  Q+F LE TF+  +YL+
Sbjct: 212 --WKKGAESP---EKKPAC-------------RKKKTRTVFSRSQVFQLESTFDMKRYLS 253

Query: 263 GPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMATA 302
             ERA LA SL +TE+QVK+WFQNRR KW+++ AAE+  A
Sbjct: 254 SSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELEAA 293



 Score = 33.5 bits (75), Expect = 0.31
 Identities = 43/137 (31%), Positives = 55/137 (40%), Gaps = 23/137 (16%)

Query: 74  PPATGGLSSLGSPPQQLSAA---TPHGINDILSRPSMPVASGAALPSASPSGSSSSSSSS 130
           P A G  S+   PP     A   +P  I ++L+            P   P     +  + 
Sbjct: 6   PDAAGTASAQPQPPPPPPPAPKESPFSIKNLLN-------GDHHRPPPKPQPPPRTLFAP 58

Query: 131 ASASSASAAAAAAAA------AAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAA-- 182
           ASA++A+AAAAAAAA      AA  A S  G LA  PRF   +     P  Y   S A  
Sbjct: 59  ASAAAAAAAAAAAAAKGALEGAAGFALSQVGDLA-FPRFEIPAQRFALPAHYLERSPAWW 117

Query: 183 ----AVAAVGRYPKPLA 195
                  A G  P+P A
Sbjct: 118 YPYTLTPAGGHLPRPEA 134


>gi|4506049 hematopoietically expressed homeobox [Homo sapiens]
          Length = 270

 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 86/288 (29%), Positives = 119/288 (41%), Gaps = 63/288 (21%)

Query: 75  PATGGLS-SLGSPPQQLSAA--TPHGINDILSRPSMPVASGAALPSASPSGSSSSSSSSA 131
           PA G +   L +P   L  A  TP  I DIL R       G A P+ +P+  S +SS ++
Sbjct: 8   PAAGAVGVPLYAPTPLLQPAHPTPFYIEDILGR-------GPAAPTPAPTLPSPNSSFTS 60

Query: 132 SASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAV---G 188
             S                          P  + +  P P    +   SAAA+AA    G
Sbjct: 61  LVS--------------------------PYRTPVYEPTPIHPAFSHHSAAALAAAYGPG 94

Query: 189 RYPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQI 248
            +  PL   P     +   +++  P     L     Q  +      KRK  +  FS  Q 
Sbjct: 95  GFGGPLYPFPRTVNDYTHALLRHDPLGKPLLWSPFLQRPL-----HKRKGGQVRFSNDQT 149

Query: 249 FALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWR----------KKHAAE 298
             LEK FE  KYL+ PER RLA  L ++E QVK WFQNRR KWR          KK   E
Sbjct: 150 IELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENPQSNKKEELE 209

Query: 299 M--ATAKKKQDSETERLKGASENEEE-------DDDYNKPLDPNSDDE 337
              ++  ++QD  +E+ KGAS +  +        +D    +  +SD E
Sbjct: 210 SLDSSCDQRQDLPSEQNKGASLDSSQCSPSPASQEDLESEISEDSDQE 257


>gi|14149611 empty spiracles homeobox 2 [Homo sapiens]
          Length = 252

 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 81/256 (31%), Positives = 119/256 (46%), Gaps = 32/256 (12%)

Query: 98  INDILSRPSMPVASGAALPSASPSGSSSSSSSSASASSASAAAAAAAAAAAAASSPAGLL 157
           I  ++++ S   AS +  P    + S ++SS      +   +AAAAAA     S+P  + 
Sbjct: 12  IESLVAKDSPLPASRSEDPIRPAALSYANSSPINPFLNGFHSAAAAAAGRGVYSNPDLVF 71

Query: 158 AGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRYPKPLAELPGRTPIFWPGVMQSP----P 213
           A     +   PP P   ++  P   A+AA   +P P +  P   P+F     + P    P
Sbjct: 72  AE----AVSHPPNPAVPVHPVPPPHALAA---HPLPSSHSPH--PLF-ASQQRDPSTFYP 121

Query: 214 WRDARLACTPH--QG------SILLDKD--GKRKHTRPTFSGQQIFALEKTFEQTKYLAG 263
           W   R     H  QG      S LL      K K  R  FS  Q+  LE  FE+  Y+ G
Sbjct: 122 WLIHRYRYLGHRFQGNDTSPESFLLHNALARKPKRIRTAFSPSQLLRLEHAFEKNHYVVG 181

Query: 264 PERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMAT---AKKKQDSETERLKGASENE 320
            ER +LA+SL +TE+QVKVWFQNRRTK++++   E  +    KKK      R + A++  
Sbjct: 182 AERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQQKKKGTHHINRWRIATKQA 241

Query: 321 EEDDDYNKPLDPNSDD 336
             ++     +D  SDD
Sbjct: 242 SPEE-----IDVTSDD 252


>gi|157426823 NK2 homeobox 4 [Homo sapiens]
          Length = 354

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 77/260 (29%), Positives = 109/260 (41%), Gaps = 55/260 (21%)

Query: 94  TPHGINDILS------------RPSMPVASGAALPSAS-----PSGSSSSSS-------S 129
           TP  ++DILS                P   GA L +A+     P G SS ++       S
Sbjct: 9   TPFSVSDILSPIEETYKKFSGAMDGAPPGLGAPLGAAAAYRAPPPGPSSQAATVAGMQPS 68

Query: 130 SASASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGR 189
            A A   +AAAAAAAAAAAAA++   +  G+ +F        P G   S     +  +G 
Sbjct: 69  HAMAGHNAAAAAAAAAAAAAAAATYHMPPGVSQF--------PHGAMGSYCNGGLGNMGE 120

Query: 190 YPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPH-------QGSILLDKDGK------- 235
            P     + G     W G    P +        P         GS+    D         
Sbjct: 121 LPAYTDGMRGGAATGWYGANPDPRYSSISRFMGPSAGVNVAGMGSLTGIADAAKSLGPLH 180

Query: 236 --------RKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNR 287
                   R+  R  FS  Q++ LE+ F+Q KYL+ PER  LA  + +T +QVK+WFQN 
Sbjct: 181 AAAAAAAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNH 240

Query: 288 RTKWRKKHAAEMATAKKKQD 307
           R K  K+ A + A  + +Q+
Sbjct: 241 RYK-MKRQAKDKAAQQLQQE 259


>gi|116174748 developing brain homeobox 2 [Homo sapiens]
          Length = 339

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 66/196 (33%), Positives = 90/196 (45%), Gaps = 25/196 (12%)

Query: 136 ASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYF-----SPSAAAVAAVGRY 190
           A+A A A A      +SP  L    P    +SP   P G  +     SPSA +    GR 
Sbjct: 63  ATALATAGAQLRPLPASPVPLKL-CPAAEQVSPAGAPYGTRWAFQVLSPSADSARLPGRA 121

Query: 191 P-------KPLAELPGR-----TPIFWPGVMQSPPWRDARLACTPHQGSIL--LDKDGKR 236
           P       +P A  P +     TP F+         R A     P + S+L  L +D   
Sbjct: 122 PGDRDCTFQPSAPAPSKPFLLSTPPFYSACCGGSCRRPASSTAFPREESMLPLLTQDSNS 181

Query: 237 KHTR-----PTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKW 291
           K  R       FS  Q  ALEK F++ KY++  +R +LA +LG+ ESQVK+WFQNRR KW
Sbjct: 182 KARRGILRRAVFSEDQRKALEKMFQKQKYISKTDRKKLAINLGLKESQVKIWFQNRRMKW 241

Query: 292 RKKHAAEMATAKKKQD 307
           R     E+ + +  Q+
Sbjct: 242 RNSKEKEVLSNRCIQE 257


>gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]
          Length = 653

 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 59/166 (35%), Positives = 79/166 (47%), Gaps = 14/166 (8%)

Query: 132 SASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSP--PPPPPGLYFSPSAAAVAAVGR 189
           S  S SA  A     A    +PA      P ++ L P  PP PP     P         R
Sbjct: 3   SCCSDSADRAFRPRGATPTCTPAQ-----PSWARLRPTRPPEPPSTRQRPPGP------R 51

Query: 190 YPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIF 249
              P+A  P       PG   + P   A  A    + +    K GK +  R  F+ +Q+ 
Sbjct: 52  ENSPVAPGPPGGAAA-PGGAGTTPQGTATAAKPKRKRTGSDSKSGKPRRARTAFTYEQLV 110

Query: 250 ALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKH 295
           ALE  F+ T+YL+  ER  LA SL +TE+QVK+WFQNRRTKW+K++
Sbjct: 111 ALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQN 156



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 20/56 (35%), Positives = 22/56 (39%), Gaps = 4/56 (7%)

Query: 29  AEMKTPLYPAAYPPLPAGPPSSSSSSSSSSSPSPP----LGTHNPGGLKPPATGGL 80
           A+   P      P   AGP +      S  SPSPP    LG H P G      GGL
Sbjct: 159 ADTSAPTGGGGGPGPGAGPGTGLPGGLSPLSPSPPMGAPLGMHGPAGYPAHGPGGL 214


>gi|70608170 H6 family homeobox 2 [Homo sapiens]
          Length = 273

 Score = 78.6 bits (192), Expect = 8e-15
 Identities = 37/80 (46%), Positives = 50/80 (62%)

Query: 223 PHQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKV 282
           P  G         +K TR  FS  Q++ LE TF+  +YL+  ERA LA SL +TE+QVK 
Sbjct: 136 PRDGGAERQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKT 195

Query: 283 WFQNRRTKWRKKHAAEMATA 302
           WFQNRR KW+++ +AE+  A
Sbjct: 196 WFQNRRNKWKRQLSAELEAA 215


>gi|94536800 empty spiracles homolog 1 [Homo sapiens]
          Length = 290

 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 71/234 (30%), Positives = 108/234 (46%), Gaps = 18/234 (7%)

Query: 109 VASGAALPSASPSGSSSSSSSSASASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSP 168
           +A+ A+     P+  +    S+A A+  S   AAAAA A  +      L G P       
Sbjct: 69  LAAAASEEPLRPTALNYPHPSAAEAAFVSGFPAAAAAGAGRS------LYGGPELV-FPE 121

Query: 169 PPPPPGLYFSPSAAAVAAVGRYPKPLAELPGRTPI-FWPGVMQSPPWRDARLACTPHQGS 227
               P L   P+    A+  + P        R P+ F+P V+++  +     A    Q  
Sbjct: 122 AMNHPALTVHPAHQLGASPLQPPHSFFGAQHRDPLHFYPWVLRNRFFGHRFQASDVPQDG 181

Query: 228 ILLDKDGKRK--HTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQ 285
           +LL     RK    R  FS  Q+  LE+ FE+  Y+ G ER +LA SL ++E+QVKVWFQ
Sbjct: 182 LLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGSLSLSETQVKVWFQ 241

Query: 286 NRRTKWRKKHAAE---MATAKKKQDSETERLKGASENEEEDDDYNKPLDPNSDD 336
           NRRTK++++   E    +  KKK      R + A++    +D     +D  S+D
Sbjct: 242 NRRTKYKRQKLEEEGPESEQKKKGSHHINRWRIATKQANGED-----IDVTSND 290


>gi|118582284 msh homeobox 1 [Homo sapiens]
          Length = 303

 Score = 77.8 bits (190), Expect = 1e-14
 Identities = 85/266 (31%), Positives = 115/266 (43%), Gaps = 39/266 (14%)

Query: 61  SPPLGTH-NPGGLKPPATGGLSSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSAS 119
           S PLG          PA GG     +P    + A   G ++  ++P +   S + LP + 
Sbjct: 9   SLPLGVKVEDSAFGKPAGGGAGQ--APSAAAATAAAMGADEEGAKPKV---SPSLLPFSV 63

Query: 120 PSGSSSSSSSSA--SASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPP----PPP 173
            +  +      A  SA + S    AA  +A     P G L G P   S SP P       
Sbjct: 64  EALMADHRKPGAKESALAPSEGVQAAGGSAQPLGVPPGSL-GAPDAPS-SPRPLGHFSVG 121

Query: 174 GLYFSPSAAAVAAVGRYPKPLAELPGRTPIFWPGVMQSPPWRD-ARLACTPHQGSILLDK 232
           GL   P  A V A         E P RTP         PP R  +  ACT       L K
Sbjct: 122 GLLKLPEDALVKAES------PEKPERTPWMQSPRFSPPPARRLSPPACT-------LRK 168

Query: 233 DGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWR 292
               +  R  F+  Q+ ALE+ F Q +YL+  ERA  + SL +TE+QVK+WFQNRR K  
Sbjct: 169 HKTNRKPRTPFTTAQLLALERKFRQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAK-- 226

Query: 293 KKHAAEMATAKKKQDSETERLKGASE 318
                    AK+ Q++E E+LK A++
Sbjct: 227 ---------AKRLQEAELEKLKMAAK 243


>gi|22749179 NK6 homeobox 3 [Homo sapiens]
          Length = 135

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 37/70 (52%), Positives = 48/70 (68%), Gaps = 2/70 (2%)

Query: 282 VWFQNRRTKWRKKHAAEMATAKKKQDSETERLKGASE--NEEEDDDYNKPLDPNSDDEKI 339
           VWFQNRRTKWRKK A E +++  +         G     +E EDD+YNKPLDP+SDDEKI
Sbjct: 55  VWFQNRRTKWRKKSALEPSSSTPRAPGGAGAGAGGDRAPSENEDDEYNKPLDPDSDDEKI 114

Query: 340 TQLLKKHKSS 349
             LL+KH+++
Sbjct: 115 RLLLRKHRAA 124


>gi|64225290 distal-less homeobox 1 isoform 1 [Homo sapiens]
          Length = 255

 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 59/200 (29%), Positives = 94/200 (47%), Gaps = 22/200 (11%)

Query: 95  PHGINDILSRPSMPVASGAALPSASPSGSSSSSSSSASASSASAAAAAAAAAAAAASSPA 154
           P  +N  +S  ++ +  G      SPS  S    S     SA  +    A ++A++ S  
Sbjct: 7   PESLNSPVSGKAVFMEFGPPNQQMSPSPMSHGHYSMHCLHSAGHSQPDGAYSSASSFSRP 66

Query: 155 GLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRYPKPLAELPGRTPIFWPGVMQSPPW 214
               G P  +S+S     P          +++V  YP   +    R            P 
Sbjct: 67  ---LGYPYVNSVSSHASSP---------YISSVQSYPGSASLAQSRL---------EDPG 105

Query: 215 RDARLACTPHQGSILLDKDGKR-KHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSL 273
            D+  +     G +  +  GK+ +  R  +S  Q+ AL + F+QT+YLA PERA LA SL
Sbjct: 106 ADSEKSTVVEGGEVRFNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASL 165

Query: 274 GMTESQVKVWFQNRRTKWRK 293
           G+T++QVK+WFQN+R+K++K
Sbjct: 166 GLTQTQVKIWFQNKRSKFKK 185


>gi|11386181 H2.0-like homeobox [Homo sapiens]
          Length = 488

 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 41/95 (43%), Positives = 53/95 (55%), Gaps = 2/95 (2%)

Query: 235 KRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKK 294
           KR  +R  FS  Q   LEK FE  KY+  P+R +LA  LG+T++QVKVWFQNRR KWR  
Sbjct: 275 KRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWR-- 332

Query: 295 HAAEMATAKKKQDSETERLKGASENEEEDDDYNKP 329
           H+ E    K K     E+  G +   + + D   P
Sbjct: 333 HSKEAQAQKDKDKEAGEKPSGGAPAADGEQDERSP 367



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 4/61 (6%)

Query: 117 SASPSGSSSSSSSSASASSASAAAAAAAAAAAAASSPAG----LLAGLPRFSSLSPPPPP 172
           SA   GSS    +S S SSAS+ ++++ +A  A+S   G    LL      +S +P  P 
Sbjct: 420 SAGSGGSSGGGGNSFSFSSASSLSSSSTSAGCASSLGGGGASELLPATQPTASSAPKSPE 479

Query: 173 P 173
           P
Sbjct: 480 P 480


>gi|121114296 caudal type homeobox 1 [Homo sapiens]
          Length = 265

 Score = 77.0 bits (188), Expect = 2e-14
 Identities = 77/241 (31%), Positives = 101/241 (41%), Gaps = 46/241 (19%)

Query: 71  GLKPPATGGLSSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASPSGSSSSSSSS 130
           GL P A G  +   +PPQ    ++    + +   P+ P A GA  P              
Sbjct: 24  GLGPQAYGPPAPPPAPPQYPDFSS---YSHVEPAPAPPTAWGAPFP-------------- 66

Query: 131 ASASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRY 190
             A     AAA     AA A+SPA L  G P   S  P PP PG             G  
Sbjct: 67  --APKDDWAAAYGPGPAAPAASPASLAFGPPPDFSPVPAPPGPG------------PGLL 112

Query: 191 PKPLAELPGRTPIFWPGVMQSPP--WRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQI 248
            +PL   PG TP   PG  +  P  W    +A     GS    K   +   R  ++  Q 
Sbjct: 113 AQPLGG-PG-TPSS-PGAQRPTPYEWMRRSVAAGGGGGS---GKTRTKDKYRVVYTDHQR 166

Query: 249 FALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMATAKKKQDS 308
             LEK F  ++Y+    ++ LA +LG+TE QVK+WFQNRR K RK +       KKKQ  
Sbjct: 167 LELEKEFHYSRYITIRRKSELAANLGLTERQVKIWFQNRRAKERKVN-------KKKQQQ 219

Query: 309 E 309
           +
Sbjct: 220 Q 220



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 27/100 (27%), Positives = 35/100 (35%), Gaps = 19/100 (19%)

Query: 37  PAAYPPLPAGPPSSSSSSSSSSSPSPP--------------LGTHNPGGLKPPATGGLSS 82
           P A PP P   P  SS S    +P+PP                 + PG   P A+    +
Sbjct: 32  PPAPPPAPPQYPDFSSYSHVEPAPAPPTAWGAPFPAPKDDWAAAYGPGPAAPAASPASLA 91

Query: 83  LGSPPQQLSAATPHG-----INDILSRPSMPVASGAALPS 117
            G PP       P G     +   L  P  P + GA  P+
Sbjct: 92  FGPPPDFSPVPAPPGPGPGLLAQPLGGPGTPSSPGAQRPT 131


>gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 67/215 (31%), Positives = 89/215 (41%), Gaps = 29/215 (13%)

Query: 81  SSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASPSGSSSSSSSSASASSASAAA 140
           +S   P +QL          +L+R + P  S  A  +A P    +S    + A     A 
Sbjct: 59  ASSRDPVRQLETPGQGFAASLLTRQAHPHHSSDARDAAGPGAGQASPLEGSEAEEEEDAE 118

Query: 141 AAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRYPKPLAELPGR 200
                     +  A LL GL R      P  P G   S         G         P R
Sbjct: 119 DPRRPRLRERA--ARLLPGLAR-----SPDAPAGALASGEPCEDGGGG---------PVR 162

Query: 201 TPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKY 260
           +P   PG   SP  R  RL               K +  R  F+ +Q+ ALE  F  T+Y
Sbjct: 163 SP---PGSPGSPRPRRRRLE----------PNCAKPRRARTAFTYEQLVALENKFRATRY 209

Query: 261 LAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKH 295
           L+  ER  LA SL +TE+QVK+WFQNRRTKW+K++
Sbjct: 210 LSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQN 244


>gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 67/215 (31%), Positives = 89/215 (41%), Gaps = 29/215 (13%)

Query: 81  SSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASPSGSSSSSSSSASASSASAAA 140
           +S   P +QL          +L+R + P  S  A  +A P    +S    + A     A 
Sbjct: 59  ASSRDPVRQLETPGQGFAASLLTRQAHPHHSSDARDAAGPGAGQASPLEGSEAEEEEDAE 118

Query: 141 AAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRYPKPLAELPGR 200
                     +  A LL GL R      P  P G   S         G         P R
Sbjct: 119 DPRRPRLRERA--ARLLPGLAR-----SPDAPAGALASGEPCEDGGGG---------PVR 162

Query: 201 TPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKY 260
           +P   PG   SP  R  RL               K +  R  F+ +Q+ ALE  F  T+Y
Sbjct: 163 SP---PGSPGSPRPRRRRLE----------PNCAKPRRARTAFTYEQLVALENKFRATRY 209

Query: 261 LAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKH 295
           L+  ER  LA SL +TE+QVK+WFQNRRTKW+K++
Sbjct: 210 LSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQN 244


>gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 76.6 bits (187), Expect = 3e-14
 Identities = 67/215 (31%), Positives = 89/215 (41%), Gaps = 29/215 (13%)

Query: 81  SSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASPSGSSSSSSSSASASSASAAA 140
           +S   P +QL          +L+R + P  S  A  +A P    +S    + A     A 
Sbjct: 59  ASSRDPVRQLETPGQGFAASLLTRQAHPHHSSDARDAAGPGAGQASPLEGSEAEEEEDAE 118

Query: 141 AAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRYPKPLAELPGR 200
                     +  A LL GL R      P  P G   S         G         P R
Sbjct: 119 DPRRPRLRERA--ARLLPGLAR-----SPDAPAGALASGEPCEDGGGG---------PVR 162

Query: 201 TPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKY 260
           +P   PG   SP  R  RL               K +  R  F+ +Q+ ALE  F  T+Y
Sbjct: 163 SP---PGSPGSPRPRRRRLE----------PNCAKPRRARTAFTYEQLVALENKFRATRY 209

Query: 261 LAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKH 295
           L+  ER  LA SL +TE+QVK+WFQNRRTKW+K++
Sbjct: 210 LSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQN 244


>gi|197333837 notochord homeobox [Homo sapiens]
          Length = 251

 Score = 75.9 bits (185), Expect = 5e-14
 Identities = 80/294 (27%), Positives = 114/294 (38%), Gaps = 50/294 (17%)

Query: 31  MKTPLYPAAYPPLPAGPPSSSSSSSSSSSPSPPLGTHNPGGLKPPATGGLSSLGSPPQQL 90
           M +P    + PP P+G       S  S +P  P G +      P A G   S        
Sbjct: 1   MPSPRPRGSPPPAPSGSRVRPPRSGRSPAPRSPTGPNT-----PRAPGRFES-------- 47

Query: 91  SAATPHGINDILSRPSMPVASGAALPSASPSGSSSSSSSSASASSASAAAAAAAAAAAAA 150
               P  +  IL+RP  P A  A+ P             S SA    A   AA+  A   
Sbjct: 48  ----PFSVEAILARPD-PCAPAASQP-------------SGSACVHPAFWTAASLCATGG 89

Query: 151 SSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRYPKPLAELPGRTPIFWPGVMQ 210
              A   + LP + S+   P P      P  A V  +  +     EL         G+  
Sbjct: 90  LPWACPTSWLPAYLSVGFYPVP-----GPRVAPVCGLLGFGVTGLEL-----AHCSGLWA 139

Query: 211 SPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLA 270
            P W              L D + ++K  R  F+ +Q+  LEK F +   L G +RA+LA
Sbjct: 140 FPDWAPT---------EDLQDTERQQKRVRTMFNLEQLEELEKVFAKQHNLVGKKRAQLA 190

Query: 271 YSLGMTESQVKVWFQNRRTKWRKKHAAEMATAKKKQDSETERLKGASENEEEDD 324
             L +TE+QV+VWFQNRR K++K+     A    +  S  E    +  + + DD
Sbjct: 191 ARLKLTENQVRVWFQNRRVKYQKQQKLRAAVTSAEAASLDEPSSSSIASIQSDD 244


>gi|226437602 NK1 homeobox 2 [Homo sapiens]
          Length = 310

 Score = 75.5 bits (184), Expect = 7e-14
 Identities = 51/124 (41%), Positives = 65/124 (52%), Gaps = 14/124 (11%)

Query: 173 PGLYFSPSAAAVAAVGRYP-KPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLD 231
           PGL  SP A A A     P +     P R+P   PG   SP  R  RL            
Sbjct: 112 PGLARSPDAPAGALASGEPCEDGGGGPVRSP---PGSPGSPRPRRRRLE----------P 158

Query: 232 KDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKW 291
              K +  R  F+ +Q+ ALE  F  T+YL+  ER  LA SL +TE+QVK+WFQNRRTKW
Sbjct: 159 NCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKW 218

Query: 292 RKKH 295
           +K++
Sbjct: 219 KKQN 222


>gi|153218470 BarH-like homeobox 1 [Homo sapiens]
          Length = 254

 Score = 75.1 bits (183), Expect = 9e-14
 Identities = 58/164 (35%), Positives = 75/164 (45%), Gaps = 14/164 (8%)

Query: 136 ASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRYPKPLA 195
           A+ AAAAAAA          LLA  P  S L+         F    A +   G     LA
Sbjct: 44  AAPAAAAAAAGELLKFGVQALLAARPFHSHLAVLKAEQAAVFKFPLAPLGCSGLSSALLA 103

Query: 196 ELPGRTPIFWPGVMQSP------PWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIF 249
             PG      PG   +P        R    A  P +      K  K + +R  F+  Q+ 
Sbjct: 104 AGPGL-----PGAAGAPHLPLELQLRGKLEAAGPGEPGT---KAKKGRRSRTVFTELQLM 155

Query: 250 ALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRK 293
            LEK FE+ KYL+ P+R  LA SLG+++ QVK W+QNRR KW+K
Sbjct: 156 GLEKRFEKQKYLSTPDRIDLAESLGLSQLQVKTWYQNRRMKWKK 199


>gi|13273315 homeobox B4 [Homo sapiens]
          Length = 251

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 49/146 (33%), Positives = 68/146 (46%), Gaps = 24/146 (16%)

Query: 168 PPPPPPGLYFSPSAAAVAAVGRY-PKP------LAELPGRTPIFWPGVMQSP-------- 212
           PPPPPPGL  SP A A    G   P+P      ++  P   P     +  SP        
Sbjct: 82  PPPPPPGL--SPRAPAPPPAGALLPEPGQRCEAVSSSPPPPPCAQNPLHPSPSHSACKEP 139

Query: 213 ---PWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARL 269
              PW       T +         G+ K +R  ++ QQ+  LEK F   +YL    R  +
Sbjct: 140 VVYPWMRKVHVSTVNPNYA----GGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEI 195

Query: 270 AYSLGMTESQVKVWFQNRRTKWRKKH 295
           A++L ++E Q+K+WFQNRR KW+K H
Sbjct: 196 AHALCLSERQIKIWFQNRRMKWKKDH 221


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.123    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,305,417
Number of Sequences: 37866
Number of extensions: 1176997
Number of successful extensions: 35496
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1079
Number of HSP's successfully gapped in prelim test: 1805
Number of HSP's that attempted gapping in prelim test: 13644
Number of HSP's gapped (non-prelim): 13244
length of query: 367
length of database: 18,247,518
effective HSP length: 104
effective length of query: 263
effective length of database: 14,309,454
effective search space: 3763386402
effective search space used: 3763386402
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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